LOCUS       DAZUJR010000001        97409 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.001, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000001 DAZUJR010000000
VERSION     DAZUJR010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 97409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 97409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..97409
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.001"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            102..1226
                     /locus_tag="ACG804_000001"
     CDS             102..1226
                     /locus_tag="ACG804_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFS4830973.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            1453..2370
                     /locus_tag="ACG804_000002"
     CDS             1453..2370
                     /locus_tag="ACG804_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4830974.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            2363..3196
                     /locus_tag="ACG804_000003"
     CDS             2363..3196
                     /locus_tag="ACG804_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4830975.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            3279..4397
                     /locus_tag="ACG804_000004"
     CDS             3279..4397
                     /locus_tag="ACG804_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFS4830976.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            4418..6289
                     /locus_tag="ACG804_000005"
     CDS             4418..6289
                     /locus_tag="ACG804_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HFS4830977.1"
                     /translation="MKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQIDYIHQGVG
                     YGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYWGEIHERDQR
                     MVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQFFKIIVGTII
                     QKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYGLIYSVLEPE
                     KPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAMLWADLLPFKL
                     GEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLWLNKIFLLLA
                     LPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPNFHTLTNEKY
                     LKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKTYGQFIVRNN
                     VRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLYETGFAIECS
                     PEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLMTWENTFIPG
                     LEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKNNKKRLKLC"
     gene            6283..7506
                     /locus_tag="ACG804_000006"
     CDS             6283..7506
                     /locus_tag="ACG804_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFS4830978.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(7592..9526)
                     /locus_tag="ACG804_000007"
     CDS             complement(7592..9526)
                     /locus_tag="ACG804_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFS4830979.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            9752..10408
                     /locus_tag="ACG804_000008"
     CDS             9752..10408
                     /locus_tag="ACG804_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HFS4830980.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            complement(10482..10835)
                     /locus_tag="ACG804_000009"
     CDS             complement(10482..10835)
                     /locus_tag="ACG804_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HFS4830981.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            11027..11956
                     /locus_tag="ACG804_000010"
     CDS             11027..11956
                     /locus_tag="ACG804_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HFS4830982.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            11967..12803
                     /locus_tag="ACG804_000011"
     CDS             11967..12803
                     /locus_tag="ACG804_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HFS4830983.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            13051..13827
                     /locus_tag="ACG804_000012"
     CDS             13051..13827
                     /locus_tag="ACG804_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFS4830984.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            14003..14746
                     /locus_tag="ACG804_000013"
     CDS             14003..14746
                     /locus_tag="ACG804_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4830985.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            14739..16319
                     /locus_tag="ACG804_000014"
     CDS             14739..16319
                     /locus_tag="ACG804_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HFS4830986.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(16570..17049)
                     /locus_tag="ACG804_000015"
     CDS             complement(16570..17049)
                     /locus_tag="ACG804_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFS4830987.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(17065..17817)
                     /locus_tag="ACG804_000016"
     CDS             complement(17065..17817)
                     /locus_tag="ACG804_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFS4830988.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNNLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            17934..18004
                     /locus_tag="ACG804_000017"
     tRNA            17934..18004
                     /locus_tag="ACG804_000017"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17966..17968,aa:Gly,seq:ccc)
     gene            18365..19090
                     /locus_tag="ACG804_000018"
     CDS             18365..19090
                     /locus_tag="ACG804_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HFS4830989.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            19345..19611
                     /locus_tag="ACG804_000019"
     CDS             19345..19611
                     /locus_tag="ACG804_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HFS4830990.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPSYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            19608..20039
                     /gene="ruvX"
                     /locus_tag="ACG804_000020"
     CDS             19608..20039
                     /gene="ruvX"
                     /locus_tag="ACG804_000020"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HFS4830991.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            20064..20369
                     /locus_tag="ACG804_000021"
     CDS             20064..20369
                     /locus_tag="ACG804_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HFS4830992.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(20450..21595)
                     /locus_tag="ACG804_000022"
     CDS             complement(20450..21595)
                     /locus_tag="ACG804_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4830993.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(21656..22303)
                     /locus_tag="ACG804_000023"
     CDS             complement(21656..22303)
                     /locus_tag="ACG804_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4830994.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            22497..22790
                     /locus_tag="ACG804_000024"
     CDS             22497..22790
                     /locus_tag="ACG804_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4830995.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            22834..23145
                     /locus_tag="ACG804_000025"
     CDS             22834..23145
                     /locus_tag="ACG804_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4830996.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            23142..23766
                     /locus_tag="ACG804_000026"
                     /pseudo
     CDS             23142..23766
                     /locus_tag="ACG804_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            23907..24065
                     /locus_tag="ACG804_000027"
     CDS             23907..24065
                     /locus_tag="ACG804_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4830997.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            24066..24428
                     /locus_tag="ACG804_000028"
     CDS             24066..24428
                     /locus_tag="ACG804_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4830998.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            24465..25313
                     /locus_tag="ACG804_000029"
     CDS             24465..25313
                     /locus_tag="ACG804_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HFS4830999.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            25303..26778
                     /locus_tag="ACG804_000030"
     CDS             25303..26778
                     /locus_tag="ACG804_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VapE domain-containing protein"
                     /protein_id="HFS4831000.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            27044..27451
                     /locus_tag="ACG804_000031"
     CDS             27044..27451
                     /locus_tag="ACG804_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HFS4831001.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            27454..27669
                     /locus_tag="ACG804_000032"
     CDS             27454..27669
                     /locus_tag="ACG804_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831002.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            27673..28053
                     /locus_tag="ACG804_000033"
     CDS             27673..28053
                     /locus_tag="ACG804_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HFS4831003.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            28187..28342
                     /locus_tag="ACG804_000034"
     CDS             28187..28342
                     /locus_tag="ACG804_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HFS4831004.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            28411..28884
                     /locus_tag="ACG804_000035"
     CDS             28411..28884
                     /locus_tag="ACG804_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HFS4831005.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            28881..30575
                     /locus_tag="ACG804_000036"
     CDS             28881..30575
                     /locus_tag="ACG804_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HFS4831006.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            30541..30726
                     /locus_tag="ACG804_000037"
     CDS             30541..30726
                     /locus_tag="ACG804_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831007.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            30730..31905
                     /locus_tag="ACG804_000038"
     CDS             30730..31905
                     /locus_tag="ACG804_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFS4831008.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            31898..33421
                     /locus_tag="ACG804_000039"
     CDS             31898..33421
                     /locus_tag="ACG804_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFS4831009.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            33477..33761
                     /locus_tag="ACG804_000040"
     CDS             33477..33761
                     /locus_tag="ACG804_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail connector protein"
                     /protein_id="HFS4831010.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            33748..34083
                     /locus_tag="ACG804_000041"
     CDS             33748..34083
                     /locus_tag="ACG804_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HFS4831011.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            34378..35004
                     /locus_tag="ACG804_000042"
     CDS             34378..35004
                     /locus_tag="ACG804_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831012.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            35746..36582
                     /locus_tag="ACG804_000043"
     CDS             35746..36582
                     /locus_tag="ACG804_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HFS4831013.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLINLYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            36646..37077
                     /locus_tag="ACG804_000044"
     CDS             36646..37077
                     /locus_tag="ACG804_000044"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4831014.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(37139..38461)
                     /locus_tag="ACG804_000045"
     CDS             complement(37139..38461)
                     /locus_tag="ACG804_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HFS4831015.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(38615..40255)
                     /locus_tag="ACG804_000046"
     CDS             complement(38615..40255)
                     /locus_tag="ACG804_000046"
                     /EC_number="4.1.1.101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043883 - malolactic enzyme activity
                     [Evidence IEA];
                     GO_process: GO:0043464 - malolactic fermentation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malolactic enzyme"
                     /protein_id="HFS4831016.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            40588..41058
                     /locus_tag="ACG804_000047"
     CDS             40588..41058
                     /locus_tag="ACG804_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HFS4831017.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            41280..42383
                     /locus_tag="ACG804_000048"
     CDS             41280..42383
                     /locus_tag="ACG804_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HFS4831018.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLKDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            42667..43347
                     /locus_tag="ACG804_000049"
     CDS             42667..43347
                     /locus_tag="ACG804_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFS4831019.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            43437..44471
                     /locus_tag="ACG804_000050"
     CDS             43437..44471
                     /locus_tag="ACG804_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HFS4831020.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            44485..44820
                     /locus_tag="ACG804_000051"
     CDS             44485..44820
                     /locus_tag="ACG804_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831021.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            44804..47284
                     /locus_tag="ACG804_000052"
     CDS             44804..47284
                     /locus_tag="ACG804_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831022.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWKLTAGPTS"
     gene            47340..48899
                     /locus_tag="ACG804_000053"
     CDS             47340..48899
                     /locus_tag="ACG804_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4831023.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            48896..50260
                     /locus_tag="ACG804_000054"
     CDS             48896..50260
                     /locus_tag="ACG804_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding oxidoreductase"
                     /protein_id="HFS4831024.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            50431..51501
                     /locus_tag="ACG804_000055"
     CDS             50431..51501
                     /locus_tag="ACG804_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4831025.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            51516..52184
                     /locus_tag="ACG804_000056"
     CDS             51516..52184
                     /locus_tag="ACG804_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4831026.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            52204..52782
                     /locus_tag="ACG804_000057"
     CDS             52204..52782
                     /locus_tag="ACG804_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFS4831027.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            53183..54094
                     /locus_tag="ACG804_000058"
     CDS             53183..54094
                     /locus_tag="ACG804_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFS4831028.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(54182..55099)
                     /gene="rnhC"
                     /locus_tag="ACG804_000059"
     CDS             complement(54182..55099)
                     /gene="rnhC"
                     /locus_tag="ACG804_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HFS4831029.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            55301..55738
                     /gene="zapA"
                     /locus_tag="ACG804_000060"
     CDS             55301..55738
                     /gene="zapA"
                     /locus_tag="ACG804_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HFS4831030.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            55797..56345
                     /locus_tag="ACG804_000061"
     CDS             55797..56345
                     /locus_tag="ACG804_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HFS4831031.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            56460..58820
                     /locus_tag="ACG804_000062"
     CDS             56460..58820
                     /locus_tag="ACG804_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HFS4831032.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEEQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLYDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            58907..59221
                     /gene="trxA"
                     /locus_tag="ACG804_000063"
     CDS             58907..59221
                     /gene="trxA"
                     /locus_tag="ACG804_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HFS4831033.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            59403..61181
                     /gene="uvrC"
                     /locus_tag="ACG804_000064"
     CDS             59403..61181
                     /gene="uvrC"
                     /locus_tag="ACG804_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HFS4831034.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            61326..62225
                     /locus_tag="ACG804_000065"
     CDS             61326..62225
                     /locus_tag="ACG804_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4831035.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            62218..63480
                     /locus_tag="ACG804_000066"
     CDS             62218..63480
                     /locus_tag="ACG804_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4831036.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            63641..65539
                     /locus_tag="ACG804_000067"
     CDS             63641..65539
                     /locus_tag="ACG804_000067"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042132 - fructose 1,6-bisphosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HFS4831037.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(65869..66588)
                     /locus_tag="ACG804_000068"
     CDS             complement(65869..66588)
                     /locus_tag="ACG804_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HFS4831038.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     misc_feature    66778..66825
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF03071"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="sodium ion sensor (DUF1646 type); this
                     cis-regulatory element may regulate processes involved in
                     with the transportation of sodium ions; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF03071"
     gene            66925..67257
                     /locus_tag="ACG804_000069"
     CDS             66925..67257
                     /locus_tag="ACG804_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831039.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            67244..69247
                     /locus_tag="ACG804_000070"
     CDS             67244..69247
                     /locus_tag="ACG804_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HFS4831040.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            69266..69736
                     /locus_tag="ACG804_000071"
     CDS             69266..69736
                     /locus_tag="ACG804_000071"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HFS4831041.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            69757..70341
                     /locus_tag="ACG804_000072"
     CDS             69757..70341
                     /locus_tag="ACG804_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HFS4831042.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            70356..71342
                     /locus_tag="ACG804_000073"
     CDS             70356..71342
                     /locus_tag="ACG804_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046961 - proton-transporting ATPase
                     activity, rotational mechanism [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HFS4831043.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            71332..71643
                     /locus_tag="ACG804_000074"
     CDS             71332..71643
                     /locus_tag="ACG804_000074"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HFS4831044.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            71665..73446
                     /locus_tag="ACG804_000075"
     CDS             71665..73446
                     /locus_tag="ACG804_000075"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HFS4831045.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            73439..74815
                     /locus_tag="ACG804_000076"
     CDS             73439..74815
                     /locus_tag="ACG804_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HFS4831046.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            74822..75457
                     /locus_tag="ACG804_000077"
     CDS             74822..75457
                     /locus_tag="ACG804_000077"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HFS4831047.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            75487..76842
                     /locus_tag="ACG804_000078"
     CDS             75487..76842
                     /locus_tag="ACG804_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HFS4831048.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(77034..78428)
                     /locus_tag="ACG804_000079"
     CDS             complement(77034..78428)
                     /locus_tag="ACG804_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFS4831049.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRTQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            78520..79491
                     /locus_tag="ACG804_000080"
     CDS             78520..79491
                     /locus_tag="ACG804_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HFS4831050.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            79488..80270
                     /locus_tag="ACG804_000081"
     CDS             79488..80270
                     /locus_tag="ACG804_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HFS4831051.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(80439..80810)
                     /locus_tag="ACG804_000082"
     CDS             complement(80439..80810)
                     /locus_tag="ACG804_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFS4831052.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            80944..81387
                     /locus_tag="ACG804_000083"
     CDS             80944..81387
                     /locus_tag="ACG804_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFS4831053.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(81430..82239)
                     /gene="yidA"
                     /locus_tag="ACG804_000084"
     CDS             complement(81430..82239)
                     /gene="yidA"
                     /locus_tag="ACG804_000084"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HFS4831054.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(82258..83625)
                     /locus_tag="ACG804_000085"
     CDS             complement(82258..83625)
                     /locus_tag="ACG804_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFS4831055.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(83609..84439)
                     /locus_tag="ACG804_000086"
     CDS             complement(83609..84439)
                     /locus_tag="ACG804_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HFS4831056.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            84602..85039
                     /locus_tag="ACG804_000087"
     CDS             84602..85039
                     /locus_tag="ACG804_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HFS4831057.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            85115..85735
                     /gene="rpoE"
                     /locus_tag="ACG804_000088"
     CDS             85115..85735
                     /gene="rpoE"
                     /locus_tag="ACG804_000088"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HFS4831058.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            85924..86430
                     /locus_tag="ACG804_000089"
     CDS             85924..86430
                     /locus_tag="ACG804_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HFS4831059.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            86447..87346
                     /locus_tag="ACG804_000090"
     CDS             86447..87346
                     /locus_tag="ACG804_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsiV family protein"
                     /protein_id="HFS4831060.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            87433..88317
                     /locus_tag="ACG804_000091"
     CDS             87433..88317
                     /locus_tag="ACG804_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFS4831061.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(88509..88580)
                     /locus_tag="ACG804_000092"
     tRNA            complement(88509..88580)
                     /locus_tag="ACG804_000092"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(88545..88547),aa:Arg,seq:ccg)
     gene            88640..89974
                     /gene="rpoN"
                     /locus_tag="ACG804_000093"
     CDS             88640..89974
                     /gene="rpoN"
                     /locus_tag="ACG804_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HFS4831062.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            90123..91214
                     /locus_tag="ACG804_000094"
     CDS             90123..91214
                     /locus_tag="ACG804_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HFS4831063.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            91255..92256
                     /gene="gap"
                     /locus_tag="ACG804_000095"
     CDS             91255..92256
                     /gene="gap"
                     /locus_tag="ACG804_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFS4831064.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            92366..93556
                     /gene="pgk"
                     /locus_tag="ACG804_000096"
     CDS             92366..93556
                     /gene="pgk"
                     /locus_tag="ACG804_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HFS4831065.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            93660..94415
                     /gene="tpiA"
                     /locus_tag="ACG804_000097"
     CDS             93660..94415
                     /gene="tpiA"
                     /locus_tag="ACG804_000097"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HFS4831066.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            94531..95829
                     /gene="eno"
                     /locus_tag="ACG804_000098"
     CDS             94531..95829
                     /gene="eno"
                     /locus_tag="ACG804_000098"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000015 - phosphopyruvate hydratase
                     complex [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HFS4831067.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            96228..97367
                     /locus_tag="ACG804_000099"
     CDS             96228..97367
                     /locus_tag="ACG804_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HFS4831068.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
BASE COUNT        32334 a        16640 c        20204 g        28231 t
ORIGIN      
        1 gtaaaatatt tttttatata aatatttgtg ttactaattc cgttaatata cataagtgaa
       61 agcgttttat ataagaactt gaaaagaaag aagggataga catgaaaaaa agatacaaat
      121 tggtgatagc tttgctaaac attaccctat tattcagctt aagtgcatgt ggaaaaacta
      181 acgaagaagt aacagcaaac atcgcagatc caatgataaa aaaagccact acattagaag
      241 tatatgtcgc aaacggcaaa ctgacaaact atgttgaaaa tgctgcaaaa atctataacc
      301 gcaaaactgg agcaaatatt gacttaaaaa ttgtgaatgt agcttcggga acagcaacag
      361 tacaaatgat caccccaaaa ttggtaacac acgaagatat gccggatatt atctccatgg
      421 cagacacttc agcagcaggt gtgctggaaa aatttcaaga tgctttttat agtgctgatg
      481 aatatggatt ttatgacaaa tatggcgatc agttttatga tcaaaaattg aatattttgc
      541 gtcaacaaac gagtaatgaa acgattattc cttgggctag tgattttacc ccagcacttt
      601 gttattatca accaaaaaaa tttgctgaaa taggtgtaga ttttgaagaa atcagttctt
      661 gggaagaata tatccaggtg gcaaaagcat taaaagaaaa aactggtagt tttggaattg
      721 ccttgccaga atctggggac caagaattgt ttatcaacat gctagcccag cagaatcaat
      781 ctttgcttga tgaagaagga aatatccgtc tgaatactaa agaagcgaaa catgctgcaa
      841 agttaatcaa agaaatgatc gactcagata ttgtacattt ctacggtgca caagatgctg
      901 agaaagcatt tcaagaatct gcaatgtttg ttgctggcgg ctggtatgct acgaatatgt
      961 ctttgaattt tcctgatgca tctgacaaat ggcgcatggc tccactgatt cctttttcaa
     1021 aagaaaatcc aggaaaaggt gcagtatcag gaggatcaag tttttatgtc cctaaagatg
     1081 caaaaaatcc acaagtggca caacaatttc ttacatttat gctgacagat gaagaatgct
     1141 tagccaacgc actggagctg ggcgtggcta catctaactc attggcctat caaacagaag
     1201 cagctgagaa aaagtttgac tactaaggag gacaaaaata ctatgaacta ttgaataaaa
     1261 tcaatgaaaa tacatcaaat actgttttac cagccactta ttcagatgct acgtcttatt
     1321 tgactaccgc tgcatataac tattggcaaa caggtgattt tgaaaattca tatctaaaag
     1381 aagcagaaaa ttttgctcat aagtacggcg taaaattaac tggtgattaa aaaatattag
     1441 gaggacttaa cgatgatgca atcttcgtta ccaagcaaga caataaagaa cagcaagaaa
     1501 aaagcaacag atacgtctca taaaaaaagt gcttatggat tggtcacacc ttttgttatt
     1561 ttctttattg tgacgatttt gattcccatc attatctcgt ttgcttttag ttttatgaaa
     1621 attggctact catttgaatt tgttggattt gacaattatc tagctatctt ccgagatcca
     1681 ttgtttatta aatcttacac gaatgttttg attatcatgg caggatcaat tccaataacg
     1741 atgctattag ctatttactt tgctgtttta ttgaattcag cacagttaaa aggaaaagga
     1801 ttttttagaa ctgtctatta tattccaacc attacatcaa cggtggctgt agcttccgta
     1861 ttcatgactt ttttcaatcc gactgggtta ttcaatggat ttttgaatgc gctaggaatt
     1921 aacggtgtac agtggttaac aaatcctttt tggatacgaa tatcaatgat catcacgatg
     1981 atttggctta gtgtaggata taacactatt ttatttttag ctggtcttca agggatttct
     2041 aaagagatat acgaaagtgc tgaaatagat ggagcatcga aatttcggca attcttttta
     2101 ttaacgatcc ccatgctaaa gccaatcatt ttaatggcca cagttttagc cactatcaat
     2161 ggcttgggta atttcaatat cccaaatata ttctttggga cttccaatgg accagaaaat
     2221 tcagctttgg tcgtaggagt caatttatat aaaacaagtt ttgaaatggt tgattttgga
     2281 aaagcctctg ctattgcctg gacgatggtg tttgtatctg ttatattatc ggctattcaa
     2341 tttaaattcg gaggtgataa aaatgactaa acaaaagata caaagcagaa tttttacgta
     2401 cgtcattatt gtgtttggtg ccttaatatt tttgatgcca tatttatata tgattgtagc
     2461 ttcaacgcaa agtaatcaag aaattttaag tggcggaatc aatttcaagt ttggggatat
     2521 gctattaaaa aactggcaag ccatcatggc gagatataat tatcccttga ttatttggaa
     2581 ttcgattgtt attgctgtaa tcagtacagt tttagctaca gccagttcta caatggcggg
     2641 ttatgcatta gcaaagtatc gttttatggg gaataaactg ttgttcaata cagttatgct
     2701 atctaggatg gtgccttttt ttaccacatt gattccttta ttttacatta tgagtcgttt
     2761 aggattatcg aatacttatg caggtgtgat catcccttcg attgccagta caacttcagt
     2821 gtttatgatg cgacaatata gcagtcaatt tcctacagca ctgatggagg ctgccagaat
     2881 cgatggtgcc aatgagtggg tgatttttac gaaaatcgct gtaccgattt tatcacctac
     2941 gattattact agtggtttac ttatctttat gggaagttgg aatcaatatc tatttccatt
     3001 agtcatgctt tcagataaag ataaatatac ggttccctta attatcaaaa atatgacggt
     3061 ttctagtaca ggtgagccaa ttaattatgg cgcaattatg ctaattttag caacttcagt
     3121 gatcccaatg gtcttgattt atgtgtgggc gcagtctaaa tttaaggaga atgacattgg
     3181 agctgcaaat aagtaaaaaa aataacgaat gttaaccatc tagttcgttc taggagcaac
     3241 tccacattca taaaaattaa aagaatggcg ggatatccat gaatgaacag acgaaggaat
     3301 ggtcaagaaa aattttgaat gtagcttctg aaaagataga tgcggaatta gacagaatgg
     3361 ggaataaaat tccatatatt tcttacaacg gaaaatatac agacgtaata aaggacagag
     3421 gaatcgactg gtggaccaat ggtttttgga gtggtatttt atggcagctc tttcacaaga
     3481 caaaacgaga aaagttcaaa gaggcagcaa tacaacaaga acaattatta gaatctgccc
     3541 tgtaccattt ttcagacgtt catcatgatg taggtttttt attcttacca tcggctattg
     3601 cacattatca acagtctcaa aacaaacata gtcgacaact agggttacat gcagctacgg
     3661 tacttgctgg acgctataat atttcaggga actatttagt agcatggaat gaccataaac
     3721 ctggttggat gattattgat agtatgatga atttaccatt actgtattgg gcttcgaggg
     3781 aaactggtga tccgaggttc tctaaaattg ctcggcagca tgcagataca acagctaagt
     3841 atctagtgag gaaagatgga tcaaccgggc atatcgcaga atttgatgca gaatcaggga
     3901 aatatattcg gttacttggc gggcaaggat acaatgagaa ttcttgttgg agcagaggaa
     3961 atgcatgggc tttatatgga ttcgcgttaa gttatcgtta cacaaaaaat ccgtactatc
     4021 tagctatagc agaaaagata gcagtaaatt ttattcagaa aatcgaaaaa actggttata
     4081 ttcctctcat tgattttgct gtaaaagatt cgaatattga taccagtgct ggagtatgcg
     4141 ctgcatgcgg tcttctggaa ttagcaggat atgtttcctc tgtacgatca aaaatgtatc
     4201 atgaagctgc tatcaatata ctccaaaaga cagaaaagca ctatgcaaat tggaatatgg
     4261 atgaagatgg gatcattgga ggcggagcag aagcatacca tagagaactg acttataatg
     4321 tgccactgat ctattctgat tattttttta ttgaaggctt acttcgatta gaacagtcgg
     4381 aattagctat ttggtagtaa aaagaggaga aaatacaatg aaacatccag taccactatt
     4441 aaggaccaga caggattact ttgacttatt taaaaagata aatcaaccac tccagccgtt
     4501 ttatcgagca agtggcgcac aaattgatta tatacatcaa ggggtaggat atggaaataa
     4561 aattgcagga atggaaggat tctctcgggt tttatgggga gcggggcccg caattgacca
     4621 attagatgaa cgatggttga aattaattct atcaggaata aaagctggaa cagatccttc
     4681 ccatcccgat tattggggag aaatacatga aagagaccag cgtatggtag aaatgcccgc
     4741 aatgttatta gcgttatatc atcatgaaca attattatgg aaaaaattag atacaggaga
     4801 aaaaagccag attattcatt ggttctcgca aatttttgaa tatgaatgtg cagatggtaa
     4861 ttggcaattt tttaagataa ttgtcggaac aattatccaa aaatttggtt atccagttaa
     4921 agaatcagca ctgaaagaag catttgataa tatagaaaat tgttatcttc aaaatggctg
     4981 gtatcgagac agttcaagag gtcgccaaga ttattataat ccttttgcat ttcattatta
     5041 tggtttgatt tatagcgtac tagaaccaga aaagcccatt agccagatat ataagaaccg
     5101 agctattgat ttttctagag actatattca tttttttgcg gaagatggtg caaatgtgcc
     5161 ttttggtcga agcatgattt atcgttttgc agtttcaagc ttttggtcag ctatgttgtg
     5221 ggccgatctt ttgcctttta aattaggtga aatcaagggg ttagtcaatc ggaatataag
     5281 atggtggatg caaaaagaaa tatttgatga aaaaggtatc ctgaatattg gttataccta
     5341 ccctcaattg acattgactg aaccctataa tagtacgtta tctccattat ggctgaataa
     5401 gattttttta ttgttggcgc tacctgaaga ccatgagtat tggacggcta aagaaatgcc
     5461 tatgcctatt cgtgaaggaa ctaaacttct ttcagaagcc aatttgctca tacaacatga
     5521 taatggacat acattttttt tgaatgcggg acaattaggg ccaaatttcc atacattgac
     5581 caatgaaaaa tatttaaaat ttgcttattc tagtcaattt ggtttttcga taccgcgagc
     5641 gaatcaattg aaagcagaaa tggcaatgga ttcaatgcta gggattcagc gagcggacac
     5701 atatatcacg accagtttta agaatgagag catcaaaacc tatggacagt tcatcgttcg
     5761 aaataatgta cgagacattg tatgtaagaa agaggtactt gcctctacat gggaacctac
     5821 tttacaggca aaaatcagaa cttggcttat tccttttgaa ggctggcaga ttcgcgtaca
     5881 caaagtagaa ttagatacag aatatgttct atatgagaca gggtttgcta ttgaatgttc
     5941 tcctgagaaa gaaggaataa tcatagaaga agacaaggaa aactataggg tgagtgaagc
     6001 tggcttttca ggtattatct gtttaagtga cgatactatt aaacgaaaat ccacagctat
     6061 tatgggtttg cccaatacaa acttgatgac atgggaaaac acttttattc ctggattaga
     6121 gggtacattt ggaaaaggaa cccattggct cggaacagga gtggttgctc atcaagatcg
     6181 ggattatagt ttagaagtat ggaacaatcg tcccaaaatt gattttgatg ggacaaccgg
     6241 gctaactatc caaaataaaa acaataaaaa aagactaaaa ttatgctaaa ggctggtggg
     6301 gaaatgcttg ataaagtgat gtttgaagag ataatacatc cagaaaaatg gataaatgaa
     6361 tgttataaag aattaatgga aaaagaatgg aataatgaga tcgagcgttg tcgcagacac
     6421 acggagaggt taatcaaacg tatcagtaac agtcagtatc aattcccaag cgagtgtcct
     6481 ataaaaggac gttatccatt aagagacaat attggttgga cagaaggatt ttggacagga
     6541 attaattggt tgttatttga gaagacgggt gatcctttat ttcaacaaac agctgaaaaa
     6601 gcagatatag attttatcca caggattgac tgtcaaatta tcactaatca tcacgatctt
     6661 ggttttttgt attctttatc aaccgtagca gattataaaa taacgggaaa tcgaaaaatg
     6721 aaggaagctt caattgatgc tgcagaaaca ttacttcagc gtttttggga gaaggcagga
     6781 gttatacaag cttggggaga tcctagtgat ccttcacaac aaggtagaat gatcatggat
     6841 tgttgcatga atcttccatt attgtattgg gcgagtgaag aaactggaaa tcaaaaatat
     6901 aaaaaagctg ctcaggctca tattcaaaat gcagcagatt atttagtaag agaagatggt
     6961 tcaacttatc atacatttta tatggatgtc aaagatggaa aaccaagata tggaagtacg
     7021 catcaaggtt atagtgataa ttcctgttgg gctagaggcc aagcatgggg gatttacggt
     7081 tttgcattaa gttatcgtta tttgaaagaa caaaaatatt ttgatttaag caaaatatta
     7141 gccaattatt ttatgaatcg gttgccagaa gataccattt gttattggga tttgatcttt
     7201 gatgattcta gcagagaaga aaaagataca tctagtatgg tgatcatggt ttgtggatta
     7261 ttagaattaa tagaatcagg tctattagac aaaacagaaa agaacttata ccagtctgct
     7321 gtttggaaaa ttatgcgaca attgaaagaa agatatgcta caacggaaga agaagatggc
     7381 tttttaacac agtctgttta taataagccc aaaaataatg gggtaaatac accttgtatt
     7441 tggggtgatt actattattt agaagcttta gtgagaatga ctagtaattg gtcttcttat
     7501 tggtgaaaaa ggtaaatatg gaatttttgt ttgataaaat aaaaaaagaa aaaccaaaac
     7561 agcatgaatg gtttctgttt tggttttttc gttaattttc atattcttct aattccaagc
     7621 ttagttcttc ccattccgtc aattttgttt cttgatcttg tctagcagct tctaaatctt
     7681 ggttcagctc attgagtttt acgtgatctt ccaggttttc tggcgcgacc atttcttgtt
     7741 ccaactgatc gatccattca tcgatccgcg ccatttcttc ttcaacctga gtaatttttc
     7801 gttgaaggct acggataagc ttttgctgtt ctttgctttg gtaataatca gatttgttcg
     7861 tgggagcagg agcagattct ggctcatctt gtgccaacaa ttcggcgatt tcttcttctt
     7921 cctgcttttt ctctaaataa taatcatagt ctcctagata gactttgctg ccattttcag
     7981 agagttcgac gacttttgtc gcgatccgat tgatgaaata tcggtcatgg gaaacaaaaa
     8041 gcagtgtgcc gtcataatcg atcaatgcat tttctaatac ttctttgttg tcaatatcta
     8101 aatggtttgt tggttcatcc aaaatcaaaa aattttcttt gttcatcgct aacttggcta
     8161 aagcaacccg tgctttttca ccgccactta gcagagggat tggtttttct acatcttcgc
     8221 cagaaaataa gaaagcacct aaagcacttc ggatctcttt ttctggagtg gtaggatgct
     8281 catcccacaa ttctgctagg atcgtcttgt ttgtatgcag atcagcttga ccttgatcgt
     8341 aatagccgat ggtgacattt gtccctagcg tttcttttcc acggataaaa gggatctggt
     8401 gaatgattga tttcagcaac gtcgatttcc cgataccatt cggacctact agagcaatcg
     8461 cttcttgacg acggatatct agattgattg gttcagataa ggtgacatta tcatatccga
     8521 tagcggcatc ttcgatttgc aagactacat ttccagaagg cttttctata ctgaatagaa
     8581 agtttgcttg tttttcatcc ccttgaggac gatccagccg gtccattttt tctaatgtct
     8641 ttctgcggct ttgcgctcgt tttgtggtag aggcgcgaac aaggttccga gcaacgaagt
     8701 cttctaattt atggatttct gtttgctgct tttcataagc cttccattca cttgctaact
     8761 gttctgcttt caaatctaga tatttcgaat agttaccttt gtaatggcgc atttttcttc
     8821 tgcttaattc atagacttca ttgactactt tatctaaaaa ataacggtca tgggaaacaa
     8881 tcaataatgc accagtatag ctttgcagat aattctcaag ccaggaaagt gtctcgatat
     8941 ctaaatggtt cgttggttca tctagaatca aaatgtcagg gtgttgcaaa agcatgcgag
     9001 ctaaagctaa acgtgtgcgc tgtccgcctg ataaagtatc gattttctga tcataaaatg
     9061 aagaatcgaa tttaaaccca tgcaatacgg aacgaatttc attttcataa ccatagccgt
     9121 ttcgatctga aaaatcgtgt tgcagccggt cgtattcttt taaataagaa ctataagcag
     9181 gtgtgtctgg cgtaccttcg ctaatgaaaa tctctagctc gcgcatccgc tcttccattt
     9241 gtctaacttg ttcaaaagct ttcagcatct cgttccaaac tgtttcattg gaatcaagtc
     9301 ctgtgtcctg agcgaggtat ccgagagtcg ctgttttatt tttagcgatc tttccttcat
     9361 caggtgcttc aattccagca atgatcttta ataaagtcga ttttccagcg ccatttctgc
     9421 caactaaagc gacacgagcg cctgtactga tttctaaatg tatgttttca aataagactt
     9481 ctgcaccaaa atggcgagca atctgattgg cttgtaataa tatcatggaa tcctcttttc
     9541 tactttgtga attctcctca aataaaaaac tatttttcaa ttagtagtct accataaatt
     9601 ccattatact gcgagatttg cagaaatgat aaataaatga ataaagaata aaatttcaca
     9661 atatctgagc aatggaattg attttttcct ataaatactg ctatgatgga gaaatcaaag
     9721 atgtaattag acaatacgtg gaggtcattt cgtgaaagat catattattc caaaggcgac
     9781 agctaaaaga ctgcctttgt attatcgcta tttaaggatt ttaaataatg ctggaaagaa
     9841 aaaagtgtct tcaactgaat taagtgaagc cgttcaagta gatagtgcaa cgatccgtcg
     9901 agatttttct tattttggcg aattaggaaa acgtgggtat ggttatgatg tagaagatct
     9961 tatgcacttt tttgcaaaga cattaaacga cgatcaattg acaaatgttg cgctgatcgg
    10021 tgtagggaac ttgggaagtg ctttactaaa atacaaattc catcaaagta atagcatacg
    10081 tatcagttgt gcttttgatg tgaatgagga aatcgttggg cgcatcgtag acggtatccc
    10141 cgtttatcca atggaagata tgtcagaaca aatcaagatc caacaaatcg aagtagcaat
    10201 tttaacgata cccgctgaaa gagcacaaga agtagtcaat cagttaacgg aagcaggaat
    10261 caaaggaatc ttgaacttta ccgctgctcg attgaatgct ccgtcagatg tattgatcca
    10321 aaatgttgat ttgacgaatg aattgcaaac cttgatctat ttcttgcatt ctgacgcaaa
    10381 tgcgcattcc gaaaatacag cagaataaaa ataaaaagcg attgaacaaa tgaaggcaaa
    10441 actttcactt gttcaatcgc ttttttctgt ttggacaacg attattttgt tcggaagatt
    10501 tcttcataag aaagggaatc atcttctgct gtcagttcat ctagtagata acggattttt
    10561 ttaaagtcga tgaaccgtgc ttgccgaaag acttcttttc cttgatgaaa aatcaggaca
    10621 actggcgcag tcagcacttc aaatttacta gctacttctg gtgtttcaaa tgcatccaaa
    10681 tgaagtgccg gaatatcata atgtgtgaga agttcctcta gtcgtggacg aacagcgtga
    10741 caaacactgc aattaggcat cgaaagataa atgacggcaa cggatgactg ttgcagtatg
    10801 tcttgaactt cagtcaagtt agtggtttgt ttcattttta ttctcccttt tatgatagaa
    10861 gtgatatgta tgagacctta atttaatggg aataacagaa aaagtcaatt gaagtgcttt
    10921 ggtaaaaaat aagagttgtg taaaaattta cagagcaact tgtttttttt gaataaaagc
    10981 gtatatttgc aaagcgaatg aactagaaat aaaaaggagg aaactcatgt tttcttttat
    11041 tccaaattcg gttttgcaga tgagtacgat tttcttatcg atcgttattg aagcattacc
    11101 tttcgtatta ttaggctgtc ttatctcagg cgccttacaa gtatttttga ccccagaacg
    11161 tgtgaagaga tggcttcctg aaaatcgtat cttctctatt tttactggtt cgatcttagg
    11221 atttttcttt ccttcatgtg aatgcggcat cgtaccgatc gttcatcaat ttgttaaaaa
    11281 aggcgtacca gttcacacag cgtttgcttt tatgctgact gctccgatca tcaatccaat
    11341 cgtgattttt tccactttta tcgcatttgg caattcttgg cagatggcaa gctggcgggt
    11401 gataggcagc ttttttgttg cccttgtgat tggtgtctgg cttgcctatt ttcaaaaaga
    11461 cgctgtattg aaagaaaaaa tcacgtctaa agtagcagaa aatcaccatc atcatgtcca
    11521 tgaagaagaa caaagtgaga agaatgaacc aaaaaatcag ctgatccatc aaactgggca
    11581 tgtgttgaca cattcaatcg acgaattttt tgatacaggt cgttatttga tcattggcgg
    11641 attaatcgca gctgcgatgc agacttattt accaactaga attatgctaa cgctcggctc
    11701 aacaaagatt ttagccatta tcatcatgct gttattggcc tttacgatgt ctctttgctc
    11761 agaagcagat gcgtttatag gatcttcttt gttaagtctg ttcggcacag cacctgtagc
    11821 tgcctttttg gtctttggcc caatggtcga tatcaaaaat ctactgatga tgaaacgata
    11881 ttttacagga cgctttattt tatcgctgat cggactgatt gcccttagcg ttattggatt
    11941 cacattattt atttaggagg gaaaatatgc tgcggttttt gattttatct gggtatttcg
    12001 aattgatgat gtacttgcaa gtttctggca aactcgatca atatatcaat gtccattatc
    12061 gctacttagc tattctttca atgattttat ctgctctttt ggctttagtt cagctgtatt
    12121 tgtgggtcaa aaacggaaaa gcagaagaaa aggcacacga gcacgatcat gaccatgggt
    12181 tgtcaaaacc ttatcaacgt ggaatcgctt atgtactgct agctttgcca gtaatcgtgg
    12241 ggacgttgtt tccaacagtt agtctcgaca ctacgatcgt agaagccaaa ggatttaatt
    12301 tcccagtaag taaagaatca gtaggggatc cggagatgca gacacaatac ttaaagccgg
    12361 ataccagtat ttatttcaac aaatcagact acttagacca aatgaatgag ttgaaagaaa
    12421 agtatgggga taagcaaact atcaagatca cagatgaaaa ctatttagaa gttatggagc
    12481 taatttataa ttaccctagc gaattcattg gcaaaaaaat cagctatgaa ggatttgttt
    12541 accaaacacc gaacgatagc aatacagata tcttcttgtt ccgattcggc attatccatt
    12601 gtgtggcaga ttcaggagtc tttggtttgt tgacgcatat gccggaagga gtaacggtta
    12661 aaaatgatga atggtataaa atagaaggaa ccatccaatc agactattat caaccattca
    12721 agcgtgaaat cccatctgta gttgttacaa acgctgagaa agtctctgct ccgaaaaatc
    12781 agtatgtgta tcgttctttt taaaagaaca aaataaataa acatagctca gacagctgac
    12841 acgcaaggac gtcggttgtc tggctttttt tgcatgatgt attcatttgt ttgatattta
    12901 ttttagaagc agcatcctga aagtatttga tatcggtttc aaaggtgttg gaaaagattg
    12961 tgaagagaat tacaatttat tcctaacatg tatgttgaaa agttgtatga aatgattttg
    13021 atagtaaaat atcgagtgga ggtacttttt atggtaacgc gtatatttat tttggatgat
    13081 agtttggttt ttgaaaaaat gctagtagaa attttggaag aatccagaat tttattaagt
    13141 ccttggaaat ttgagatcgt tcagggattg aacgttatac aatttgttga attcattaaa
    13201 aataatgaaa tctattcctc agatattttt ttcctagaca tcgatttgaa cgcctattat
    13261 agcggtatcg aactaggcga aatgcttaga gaaaagaatg aaaagtgtaa aattgtttat
    13321 ctaacgtctc atccgaataa agcaataact gttattaatc gaaagattac gcctagtggt
    13381 tatttgataa aagaattcac ttatgaaaaa aataaaaaaa gcatccaaag ttacttattg
    13441 aaagaaaaag aaaactatcc tgttcaacat gctacgaaaa aaaggtggac aactgtccgt
    13501 tatggtaata gcgatcacta tatccattac gatgaaatcc tttatctaat gagcatgcca
    13561 ggttataaaa ataaaatagg cctagtattg aaagatgaag agattctcgt aaacggcaca
    13621 attaaaaaat ataaaaaatc actcgaatat gagtatttat gtaaagattt aaaagcttat
    13681 atcattaata ctgaaaacat tacatctatt agcagagtaa acgaaatagt aacatttgca
    13741 aatggagaac aactagagat gggaaagaga agtattgata aactaaagaa ttttatgcaa
    13801 gaaaagatag aaaatgaatc attttaaaga aaacaaagac tcatatctta cctgttagaa
    13861 gagtgttttc ctgtagaaga gaacaaccca agtagcagcc tagtcgtttc tatccttttt
    13921 tgttatgcac tctttttgac atttactcca ccaataacga agggtacaat aaaaagtaat
    13981 aacaaacaaa aggagtacag aaatgattga attcatcaat gtaagtaaaa gttacgggaa
    14041 aaaacaagca ttaaaagact tgtctctctc gataagacaa ggggaaattt ttggattttt
    14101 aggacataat ggtgccggaa aatcaactac gattaaaagt ttagttagta ttattgaacc
    14161 atcatcggga acgattttag tagatggaat gaaattgacg gaaaatcgat tgagtatcaa
    14221 acaaaaaatc ggttatgtgc ctgattcccc agatattttt ttacaattga cggctggaga
    14281 atattgggac ttgatttcag ctgcctatga attagacaca caaaaaaaag aaaagcgttt
    14341 agcagaattg acagcgcttt ttgatatgta tagtcatcaa aatgaaacaa tcgcaagttt
    14401 ttcacatgga atgcgtcaaa aaacgatttt gatcggcacg ttgctgccag atccagatat
    14461 ttgggtattg gatgaacctt tgcaaggact tgatcctcaa gcagcatttg atttgaaaga
    14521 aatgatgaag gctcatgccg caaaaggaaa aacagtcatt ttttctacac atgtattgga
    14581 taccgcacaa cagttatgcg ataaactggc tattttgaag aaaggtgaat tgatttatca
    14641 gggggcagtt agtgaattat tgaatggctc acctgatgaa acgctagaaa agatttattt
    14701 gaaaatggct ggaaggcaag cgacaggaga tggaccgtat gtataagcga caattattag
    14761 aattaattcg agttaatctt ttatatgtta atccacagct cacgaataaa gcaagagaga
    14821 aaggaaaaaa gggaaagcga ttaactatct atcttttgtc tcaaaatctt ttttcagggc
    14881 tgattttttt actgatttac ggatttgcta tgtttgctat gaactttgtt aaattgccag
    14941 gtttctttac ttattacgtg gcactttttg gtatgttagg tttaactcaa agtatatcag
    15001 tcatttataa tatctttttt gaaggaaatg acctgcaagt atttttgcct ctgccttttg
    15061 gacaagaaca ggttttttca gcaaagattt tggtagttgc tttgaccatc attccttttg
    15121 tttttccgct tctagtcatg tttattttaa ccggatggcg agctgatcta gggattttgc
    15181 ttactatcat tatctcaatc cttttgtttt ctctattttt gattattctt ttttgtctgg
    15241 ctagtttgat tgtttttggt ttggctcgaa cagcagtgtt taaaaaacat agaaaaacag
    15301 tttctagtat cttgcttggc agctcgatgc tgatcgcatt tgctggaatc atgtggatga
    15361 atcatcaaac ggggactatt gaaaatgagt taacagatcg gcatccgatt tcgatattat
    15421 tgccattcta tgatgctgcc agtcagccac tttctcaaca aggtttattg ggttggggaa
    15481 tactagctat cacggctctg ggatttttcc ttgctgtaaa acagctgata gtaccaaagc
    15541 ttacagagca actgactgat tcaaacagtg agttcaaaat aaaaagaacc cataaaaaga
    15601 accaaaatgt gcatcagctt ttatttagtt acaatgctca attagtaaaa gaacctaatt
    15661 tgattatgca agttctttct tcttccttgt taactccaat catttttatt cttgcttttg
    15721 ccctaggagg cgaaataaaa ttaactgatt tagataataa gttaatcggt gttgttttcc
    15781 tggtagggat cgcattggct ttcttaacag ttaatcagac ttcttttatc agcaatctta
    15841 tttctttgga tcaagaaaat tttctgttta tccgttcttt gccaatctct atgaaccaat
    15901 atttaaaaga aaagttcaga ttcggatgga tattgcagag ttttttaact ggtgggatcg
    15961 cattattaag cggactgtct tttcagctgc ctttgttttt tatccctagc ttgctatttg
    16021 gttctttatt cggctgctac ttattgtcac tacgttattt cgctagagat tatcggttgc
    16081 tgctgctgaa ctggaccaat attaaccaat tatttaacag aggttcagga agtttgggtt
    16141 tagtcgcaac tatgatgggt tcattgatca tcagtattat tcttatcgtc ttatacggaa
    16201 tgttggcttt gttttatcca ttttggttag tgaatattcc tgtgatcggt ttagttctaa
    16261 tactttccgc tctatggatc gtttattatc aacgaacgtt ttggaaaaaa tttgaataaa
    16321 gaagaggggc cgtgacaaaa atcatgtcgc agcccctttt ttacagatag agggtgttca
    16381 aaagtcagtt tctcagtatt aagtcaattt tatgtaaaaa tgtgagaagc tatttttaca
    16441 aaactttttt taatactcat aattacttct tattgctcct gcggttactt gtcgcaatgt
    16501 ttgtgagata ttttgtcatc gctcaaggct gaacgtctct ttcacaacct tttctttgtt
    16561 acacttcgtt tatttaaaaa gccgtttttt tcgtttcatc atgattgcgt cacgctttac
    16621 tttgaaatta cggatgttat ggttaaagac ttctgataat acaagaccta aagcgattgc
    16681 tccagcaatc ataattgctt ggaccgcata atgagccgct tctcgatagg attcagtaac
    16741 gagatttcga accgcttgat aagctaaacc accagggact agaggaacca tcccgggaat
    16801 attgaaaatc gttacgggca ttttcaaacg tttagagaaa agatcgctga tgaatgctac
    16861 tcctaaagaa ccaagcaatg aaccaaaagc agcagatccg cctatttgaa cacagatcca
    16921 gtagatcatc cagccaaaag caccagaaag accacaacaa atcaatgaac gcctaggtac
    16981 atttgtaata acggcaaatg ccgcagtcgc taaaaaacta aaagaaaact gaataaatat
    17041 cgtccccata cttgtgttcc tttcctaata aaaaagctgg aaaataaaag caatcgcaaa
    17101 accgatcatc gtagcagtca tcatcgcttc tgttccgcga gaaactcctg agacataatg
    17161 tccagctagc aaatcacgga tagcgttcgt aatttgaact ccaggaacta aaggcatcac
    17221 acatccgata atgattagat cctgattgct tcctaagcca aaacgtacgc tgtagatagc
    17281 ggctatgcca atcaataaag aagataaaaa ttccgataaa aatttgattc taaaaaattt
    17341 caaactatat agataagctg cgtatcccaa tcctccaatg actaaagtca caggtaaatc
    17401 ggtcatcttt ccgccaaata acaccataat tgttccactg atcactgccg cgctaacgat
    17461 ttgcaaccag acaggaaaga aagaacggtc tcggtcgatt gcttgcagtt cgcagtaaag
    17521 ttcttctaat gttagctctg aagcaacata tttacgtgaa agattattta cttttactac
    17581 tttttctaaa ttaatcgaac ggttggtaat ttgttccatt cggatggtcg aggtacgatc
    17641 aagaccaata aagagaccgg tttgagtgac atagctgacc aaacggaaat ttccagaagc
    17701 taaagcaatt cgactcatcg tatcttctac ccgatacatc tccgcattgc tttccatcat
    17761 gattttccca gcgagtaaac aagtgtccag caacagatct aattcttttc ccgtcatagc
    17821 atcttctcca ataattgatt gattagtttt attttactac aaaacatacc agaagcgtaa
    17881 agaataaaaa aacttgagga aggaataaaa gaggcgtata ctgtttttgt attgcgggtg
    17941 tagtttagtg gtaaaatccc agcttcccaa gctgatgtcg cgggttcgat tcccgtcacc
    18001 cgcttaaaat aggttgtgaa aaagctgctc tgcaacaagt aataagaaca gccaagcaaa
    18061 aacaacttct tatgttttta acttggatgg acttattacc gcagatgcaa gcttttgcgc
    18121 accgtttacc aagcggttgt gaaatcagtg tattgtcttg agtatgaaga aaatttttga
    18181 ataataataa ataccttaca gatagagtgg tgactgatta gagacgagga atccgtctct
    18241 tttttgtatt tttaagccat cttaaaacag gttttatttt ttgctgtttc tatttctttc
    18301 tagtatttat ttatagggga acatatgtta agatttaggg agctgttagt aaaggagtaa
    18361 agaaatgagc aaaaaaacaa ccaaggcgat cgtggggatc gtcgctgctg tgattgcagg
    18421 ggcattcggt gtttccacca cacaaaaaga ttcagatatc tttcagcaga ttacaactat
    18481 ttttgattcc acaccacaag cttctcaagt agcggatgtg ccagaatatg atggaaaaca
    18541 tcaagaaata gaaatcaatg ggaatcagcc ggaatttaca aaagaggatc ttagcctttc
    18601 caaaggaaca tgggaaagct attcaaatat tgataaattg aacagagtag gacaagccaa
    18661 tgctatgctt ggaaaagatt tgttccctac tgaaaagaga gagcctttgt atattgaccc
    18721 gacaggttgg aaacaaaaga aattaagtga cgggcaatgg ttatataatc gcagccattt
    18781 aattggtttc cagctgactg gtcaaaataa caacattaaa aacttgatga cagggacacg
    18841 ttcgttgaat gctccataca tgcttgctca cgaaaatgat attgcggcat atatcaaaga
    18901 aacaaatcat catgtacgct accgtgtcac tcctcatttt gaggggaatg aactggtagc
    18961 caggggagtg caattggaag cagaaagcat tgaagacaaa aaaattgaat tcaatgtctt
    19021 tatctacaat gttcaagatg gctacacgat caattatgag acaggacaag caacaaaaac
    19081 aaaaaattag tagcagctat tcgaattttt tatgaatatt atgaaaaaat tgtgtaaaaa
    19141 catacattca aagaaatata gcgtatactt tatgaaaaga gtacttttga taaagctaca
    19201 gaaaaaagga aaaaaacata caaatagtgt ttcttaattt attcggaagt ttggaatatt
    19261 tgtttgtagt tttccctttc ttcgagtaaa ataaggttgt agaaggtaag ctggaattac
    19321 cttgcgggaa agaggtgtag aatcatgggt tttacagatg aaaccgtacg ttttggtttt
    19381 gacgatagtc gcaaaaaaga agtgagcgaa acattagcga ttgtttatcg ggctttggaa
    19441 gaaaaaggct acaatccaat caatcagatt gtcggctact tgctttctgg agacccgtcc
    19501 tacattcctc gttatcgtga tgctcgaaat ttgattcgcc gtcacgaacg cgatgagatc
    19561 atggaagtaa ttgtcaagga ctacctctca aatcatggag tgaatttatg agagtaatgg
    19621 gcttggatgt cggttctaag acagtaggtg ttgctatcag tgaccccttt ggctggacag
    19681 ctcaaggagt agagatcatt cggatcaatg aagcagaaga agagtttggc tttgatcggt
    19741 tgaaggaatt agtagcacaa tatgaagtag accggtttgt agttggatta cctaaaaata
    19801 tgaacaattc catcggacca agggcagaag cttccatgtc atacggagaa aagatcaaag
    19861 aactattctc cttgccagtt gattatcaag atgaacgatt aaccactgtt caggcagaac
    19921 gtatgctagt agagcaggca aatacttcaa gagccaaacg aaaaaaagtc atcgataaat
    19981 tagcagctgt gatgatctta caaaattatt tagacggctc aggtaagcaa ttattttaat
    20041 aataaaagaa aagaggtaat cttatgacag aacataacca ttcccacgac catgaaggac
    20101 acgaacacat cacattggtg gatgaccaag gaaatgaaac attatatgaa atcctactaa
    20161 cagttgacgg acaagaagaa tttggacgta actatgttct tttatatcct gctggtgttt
    20221 cagaagatga agatgtagaa ttacaagctt atgcatacat cgaaaacgaa gatggaacag
    20281 aaggcgagtt agaacaaatc gaaacagacg cagaatggga catgattgaa gaagtattca
    20341 atacattcat ggcggaagaa gaagaataga ctataaagct aggagaaacc ttgatatgat
    20401 agggtttctc ctttttttat tttttactgt atgccatatt gtatgccatc tagtcaatat
    20461 ttaagtgttg tactaatttt tcaacagtct tttctttcgt ttcttttgcc aagtgaccgt
    20521 aacaatcgat cgtctgacta atttttgtat gccgtaatct agtttgaact tctaccatag
    20581 tagctccagc gtccaagagc attgaagcat gagtgtgtct tgctacatgc acaccgagaa
    20641 atggaaccat agctttttca caaatagtaa tcaatcttgc ataaatagcg tggtgtgtga
    20701 ttagttcttt atagatacca caaaaaatca tagtcggatc agttacacca agtgtcagca
    20761 tatatttccg ctgattaatc tgccattttt ttaatataga aattgttctt tcatctagtg
    20821 gaagaacccc agcactacaa tcagttttag gatcactgat tttatagcca tttttggatt
    20881 ggcttagtgt tttattgatg gtgaccgtat tttcttgaaa atcaatgtct gaccaattca
    20941 atgcaagggc ttcactgatc ctaaccccgc tataaaagag aaagcgtagt aacgttttat
    21001 caaagtcgtt tcgataagtt tcaggtttgc tgtttaggta atcaaacaag gtgatcagtt
    21061 gttctttact gtaaactttg accttttctt tatgcttagt ggtggttctt ttaggcatta
    21121 atacgttgtc tagtggatta gtctcaataa tcccaagatt gatagcgtag ctaaaaatac
    21181 gcttagaagt tgaatgaagt accttgtatt ggtcagtagt ttcagcccag ctatttacaa
    21241 tttgttgggc tttttttacc gtgacttcat tcacacgaag atttccatat tttggaagaa
    21301 tccactttct aaacttgatt tcagttttca tgaaggtggc ttctcggaca gtggttttat
    21361 atgtttctag ccacaagtca taaacttctt taaacgtttc gttgttcgct tttttaatac
    21421 cgtttttatc gtagtccact tgcaagcgtg acaaggcaag ctgggcttct ttttttgttt
    21481 tgtaacctcg tctacgaacc ttatcaggtt tgccagtcat tttgttcatt ccaagatagg
    21541 cttcatagag ccaaaattta ccttttttag tttcatattg cttgaatgtt gccataatag
    21601 ttttccctcc atagtgtagc aagccgtggg ggcggttgga ggaggcagtt tattattatt
    21661 ttgaatagtg tttatttagc tcagtaacaa gagctgtgaa ctcttttaga agatcatttt
    21721 cataaaattc ttgatactct tttttctcat ctgtattttt ttctgaatca ttaattaatg
    21781 agtcatatcg taaaagcgta tttagaagag ctgcgagata agcaattggg gtactcccgt
    21841 caggaaattc aattcgagat cctgttttaa gatattttat tgcgtttgtt aaataaatct
    21901 tctgtgagac agtcaggtta tcttcttcga tgttattgat agcattagaa agattagaat
    21961 caattataga gttatttttt tcaatagttt ttttcaattg cttttcaagc acatttcgct
    22021 taatttcggg catcatatgc atatctctta atgtataaga tccgtttaat agataggtag
    22081 tggatacatc taataccttt gaaagttgtt taagcctggt gttattggga agattatagc
    22141 cattttccca attactaacg gcacctttac tggccggtgg ggataattta cctccaagtt
    22201 gttccattga gagtcccttt tcaattctag ccagtctaat tctttgtcct gtctccactg
    22261 cttcggggta tttttttcta gccacatttt caccaccatt catatatttt ctctactata
    22321 tcacgattta aatatgtgtg aaacataaaa gttcaaaaaa gtatgttaaa attcttgcaa
    22381 atgaaaaggt atgatggtat attgagttta taagaggtat agaaatgtat tcaagagcct
    22441 cttgcatttt tttaaaatct ttgtatagaa atgtatgcta acgagggggg ataaatatgg
    22501 aattaaaaat tgacaaactc acgcttgatg atccagcttt taaaattatt gacgatcgag
    22561 ttgttcaaca agtagagcaa actcaaggaa cgttactttc attattagaa aaaaagtacc
    22621 agtttccaaa atatatgaac aaggcacaag ctgctaagta tatgaacgtt tcatacaata
    22681 ctatgatgca gaaatatgtt cctaacggtt taaagttgat tatagttgat ggagtcgtaa
    22741 gaatttcaca agatgaatgt gatcgcttta tggaagaata ccaaaaataa acgcaagccg
    22801 tgggggcaaa gggattaata ggaggaaata ataatggaat cgacacaaaa taaagcaatc
    22861 gaaaaagtat tatcaacaat tcttacagaa gacacagcgg cagaattagc aaacttggaa
    22921 ggcaaagcgc tagaagaaac gtttgaatgt ttgtacgaac aaatggacta tcaaaaattg
    22981 ctaccacaag aaccaacggt aagcggagta ttgcgtggct tgaacgattt agtacaagca
    23041 gagtttaaag aacgactttc tattgaagag tatcaagaaa ttttgtatca gcaagttgag
    23101 ttgttagcga gcttgctagg gcttgaactg gaggacgttg aatgaaaact gaaatttgga
    23161 acggacacat tataagattt gtcgatatta atgatgaatg gtgggcagtg gcgaaagatg
    23221 ttgcggaagc gttaggtctt aaacaggtta ctagagccat tcactctttg cctaaagatg
    23281 gggttactac tagtaaggtc atcgattcat tgggcagaac acaagatgta aacatcatca
    23341 acgaaaaaaa atatttaccg catggcattc aaaagccgta aaaaagaagc cgaggcattt
    23401 caagactgga ttttcgacat catcaaagaa ctacgccagt ccacaggact tgaaggcttt
    23461 caagtattcc gcatgctaga caaagaacac caaaaagaag caatgactaa attaagccac
    23521 gctattactg aaccaaaacc agtagactac attaaagcga atgtgatagc caataaagct
    23581 gtatcaacta tttatggtca ttccaaaatg gtaaaaaaga aagatatgac tcctgaaatg
    23641 ttggttgatc gtgaacctat tttagatgag acagtagaat taatgactgt taaagaaaaa
    23701 tatgggttgc agttttcagt gagtgagaaa atttataatc gttctgctga attgcagaca
    23761 acttaggagc attaacatga tcgagaacaa agaaaaagcc ttatccataa cagtcttggc
    23821 ggacaggata aaggcaactt aattgggata aaacccgata ttctttgttc cgattatacc
    23881 atattaaaaa atcggaggga accattatga aacgaaactt aattatagga agcattttaa
    23941 tcggcggaat tttcggctta ttaccattaa ttgcaaaaat agctatcttt gcaggattag
    24001 cgttatatct cttcactgct tatgacgagt acgactatca attaagaact ggagggcata
    24061 agtagatgta caaaacaaaa ctattaaacc aactcgatag ccttgaatta gaggaaatta
    24121 atcaagggat cgctgaacta gaaaataata tcgggaaaac ctactttgga aattcattca
    24181 atgaaaaact aacagttttg tatgtactca aaaaacatgc agaacacaaa ataatttgtc
    24241 gagaaatcaa cgagctaaaa aatcagattt taaccgcatg gttaaacatt actgatatgc
    24301 aagaagcaag ggtgaaaaca tttaatacat gggtaaagta tcagaatcaa ttaaaaggtg
    24361 ctgaatttgt tcgggatggg ttgaaatacg aacttgagca gttgaagctc atggaggtgt
    24421 ctgaatgatt tataccagta ttttgaaaaa ggaggagagg tttattggca aataattatc
    24481 aagcagcaac ggaattacaa aagtcgggat ggtcaattta tcccttatct cctggaacta
    24541 aaattccaat aaaaggctct agtggttgga atgatgcaac taacgattct aatcaaatta
    24601 atgaatggtg gacggaagat gcaactagaa atattgggtt aatgcttgaa gatcatcaaa
    24661 tggtggtagt tgacctagat caacattctg aaacacgaaa cggcgttgag aattataaaa
    24721 aacttgcttc aatgtatgat ccatttcctt ctacttatac ggaaatcaca ccaggtaaag
    24781 gaatccattt cttctttaaa attcctgatg gtgtaattat ccaacaagaa acaggtgcat
    24841 ttgctgatat cttcgggcgt gatgataaag gtaaaagttt aagcgggatt gatattatca
    24901 ctaaaggagt tccaatagcg ccaactatga ttatttcaag aagtgttggg agagcatatg
    24961 aacctattga aaacgtatct ctaaataata ttgcaccagc tcccgattgg ctagtgaacc
    25021 tactgctaaa aaaaccgcaa gaaataaaga ctcaataccg acccgtagca aaaacaggga
    25081 cagcaaaaaa attagatatg attgttcaag gcgctggcga aggtagtaga aacgatcatt
    25141 taactaagtt atgcggttgg ttactatggc acggtgtaga taatcaaact ttagcagaat
    25201 tgatttatac agcaaatgcg tacaatgaac caccgctaaa agataaagaa gtgaatcaaa
    25261 ttattcgatc gatgattaaa aaagatttga gggggaaagc tcatggctca taagcataaa
    25321 ttagatagta ttttagactt tcccgaagcc agcgagcgtg aagacaatat cattgaattg
    25381 aaaacctgga tgtcacgatt aagatgcaat aaagacgatc agattaaaag taacagtgtt
    25441 gtgaatgcag aattgatttt aaccaatgat agcaatttag ctggaacaat tgcttataac
    25501 gaatttagcg gatacattca cctattaaaa gattctcctt ggatcaatcg taccgctgga
    25561 gaatgggaag acagttttga ggatgcctta acggcatata ttgaagaaaa ctacaatgta
    25621 gtttttgatg acaacaaaat acacaaagca gtagtaaatg tggctagaaa gaatgttttc
    25681 aacccagtaa aagaacgtat cgaaaaagtt aaatgggatc aacagcctag actggaaaca
    25741 ctgtttattg accttttagg ggtagacgac aacctttaca cacgagaagt aacaaaacgt
    25801 tggatagtcg gatcagtcgc acgtatctat aaaccaggaa taaagtttga gatcgttcca
    25861 gttttggatg gaccgcaagg gattggtaag agtaccgttc cagcattact ttacacggat
    25921 gattttttca ccgattcatt agattcgcta ggtgaaaaga aagatgatta tatgcagctt
    25981 caaggcaatg taattattga acttggagaa ttatcttcaa tgaacaaaac taaaattgaa
    26041 cagataaaaa acttcatcag tgccaagatc gataaaatta gacctcctta tggtcggaat
    26101 gtcatagctt gggcaaggca atgtgtattt attggaacgt cgaatgatgg gcagtatttg
    26161 aaagatgata caggaaaccg ccgtttttat cctttgcctt gtaagaataa gccaaagatg
    26221 aatccgttta aaacaaagga tgaatatttt cttcaagtgt tagctgaagc aaaggtgctt
    26281 tttgataaag gacaacgaat ctattttagt cccgatgaag ataaagaagt cttagaaatt
    26341 gcaaaagact atcaagagga tgccaagatg gagaatccaa ttaaagaagc aatcactaaa
    26401 tatttggaaa tggaaatccc gtataaatgg gaagaagctc cagcgtgggc gagacgttct
    26461 tattatcaga actatcctga cagtaaatgt aatgagaaaa atttacagca tttctataat
    26521 ggagctacta tgcaacaaga gttttattta gttgatagcg tactcaccgc tgatattttg
    26581 gaagctgttt ttgataaaca agcaaaggat ttattgaatg gtcgatcaga tgcagaaact
    26641 aaaaagattg ccttgattat tagcagtatt cctggttggg aacggaagca actgccaaaa
    26701 agaaataaac gacgaggatt ttacaataag tcaaatgcct atgaaaataa aaatcgagct
    26761 ggaaagtaca aaaagtaacg ggtagtaacg ggtcagtaac acctagcccg ttactagttt
    26821 acccttactg ccccaaggga tacagcaatt tggtaacggg gtaacacctt atttccttaa
    26881 aacttttgaa atagttagct aatatgctgg ggaataatgt tactggattt tacccgttac
    26941 ctgttaccaa aacgctagaa cccttgtccc cgttgggatt gagtggtaac gggtacctgt
    27001 tacgtaggtg ttaccacgtg ttacgaatca aggaggaaag taaatgctca atattatttc
    27061 aacaaacaaa gcaccgaact ttcaatatac agatgaaatg gatcggtttc taatgaacac
    27121 gctggcattt agtgtgggat tggtaacaga agattattcc acatttgatc cagaagtatt
    27181 aaagataatg gaagaagaac ctgattggct gcaggagtca gtagcgtggt gtcaatcgct
    27241 agtagtggga tcattggtag atagtggcaa ctatgatgat acaggtgagc taatggatga
    27301 atttaattgt ctgcttaacc tatatgatcg agcgagacaa cgagagctta catcgaatga
    27361 ggataatttg tttttaaaca tccatgataa gttcttggct ttgctactaa cagatgatga
    27421 attgataact aatttattgg aggtagaata attatgcata tggaaagtat tagatacttc
    27481 gatggtgaga aacacattga gtattcaaac actcaagaag atgtagactt tattagtttt
    27541 gaggaagata aaatcactaa agttaatttt aaagacggaa cgtgcttgaa gatagtttcg
    27601 ccttatattg aatacaaatc aaaatgggaa caagatgatt ctgacgaacg agatcgcttt
    27661 ggttggtaat ctatggcagt taaaaaacaa tgtaatcatg ctggatgtaa aacattgatt
    27721 gattataggc agaagtattg tgggaagcat aaagcaaagc aaacggcaat taagcgtgaa
    27781 gaaagaaagc aaagcgaagg taaatatttt caattctatc aaagtagaac atggcgaaag
    27841 gcttcatact tgtatcggtt aaatcatcca gtatgtgagg attgcctaga agaaggcttg
    27901 ataaggaaag ctgatgttgt agatcacaaa attgaactaa aagatgattg gaatagacgg
    27961 ttagatgaaa ctaattttcg ttctttatgc catgcacacc ataattccaa gacagccaat
    28021 gaaagacaaa gacgagaaaa gagtaccctt tgagttaagg gggcatagtg tgaaacttac
    28081 tgacaatcga tgcctactca ttttggtaca aataaccgtt gtgaaaaggc ataagggtaa
    28141 ttacaaataa cgattacact tgtaatcaca agtgaaaaag tatataatga aagtaggaga
    28201 tttattgaaa aatacaattg ttattactga taaaacaggg aaacagcgca ccattgagtt
    28261 acctcatttt ggtcaagtga ccattcaaat gcagaacgga aaaatcattt atatagataa
    28321 attagataaa gaaaaattct gatcgaaaaa cgaaggaatg tgagcttaat tgcttacgtt
    28381 cctttttctt ttgtctgaaa ggaggacaac atgggacacc ctaaaatatt acacgataca
    28441 aaaggcaata tatcaagtga agaaaaagca atccgtgtgg acgctagaga agaattgttc
    28501 aagcagcaac cattaataaa tatcacgccc cctgactgga tggcagcgag cgctagaagt
    28561 gaatggaatc gtatcgtacc aacattaaaa aaagattatc cattgagtga agcagattat
    28621 ggttcattgg tagcctattg tttagccttt gctcgaatga aaacagccga agccgagata
    28681 agaaaatcag gtacgtttat cacatgcgaa aacggagtaa agaaagccaa tccagcggtt
    28741 cgggttcaat cacaagctat gagtgatttg aaaaaacaag ccacctcact aggtatgacc
    28801 ttagaatcac gatcaaaact agctttgaac aaggttaaaa atgatgaacc cgaagacccg
    28861 ttcaaagagt tgatgaattc atgaatgatt acattgagaa agtcctatca ggtaagctga
    28921 ttgcacccaa gaaaattatc caagcgtgtg agcgtcatat aagcgatttg gagcgttcta
    28981 agtcagatag cttcccttat gtgttcgatg aagaacaagc caccaaagcg attaaattca
    29041 ttgagttgct accatctacg gacggtaaag caatcaagat gttaggattt caaaaattca
    29101 ttctaggcag tctttatggc tggcgtacta aagaagggaa ttacaggcga ttcaatcgag
    29161 cgtttaccag tatgagccgt aagaatggga aaacgtatat cgcaagtggc atggctgcca
    29221 atgcgttgat tatggaacaa gaaccagcag aagcaaggca agtattgttt gtaagtaacg
    29281 ctttgaaaca agctaaattg ggctatgata tgctgtctaa ttcacttaga aacgtggtca
    29341 agtctagtaa gtttttaaga ccacaactga aaattatgaa ctctaagatt cagcacttgc
    29401 cctctaattc gttcgctatg gcactggcta gtgaaaccag cacgctagat gggtttgcac
    29461 caacaaccgc aattcttgac gagtggcacg aagcaaaaac tcgtaaaacg tacaacgtca
    29521 ttaagtcagg aatgacccaa caaaagaacg gcttattgtg tgttattagt accgctgggc
    29581 ttgatttaaa cgttcctatg tacgaggaat acttattgtt agatcgtgtg ctaaaaggcg
    29641 aagaacaagc cgacaggtac tttatagcga tatgggaatt ggacgatccc gaagaaattc
    29701 acgatcaaga gaaatggatc aaagccaatc cgatttttga aagtgaagaa atcaaaaaag
    29761 taatgattcc aaccattcaa gatgatgtga accttgcttt gaaacaaaat aaccttaatt
    29821 ctgtattggt gaaaaacttc aatttatgga gacaagcgag tgaggacagc tatatgattg
    29881 ctgaagactg gcaggcaacc gaagtagaac cacaagatat tacaggcaag cccgtttata
    29941 tcggagtgga tttatctaaa acagatgatt taactagcgt ttcatggatc gtaccgctag
    30001 ataacggcga actttattgt gattcacata gctttgtagc caccaaatat gggcttcaag
    30061 acaaagaaaa gcgcgacggt ttgccttatc gagaactaga aaaagctggt gagtgttcca
    30121 ttactcaatt agaaagtgga atcgtggact atgaccaagt atttcagttt attcaagatt
    30181 tgattcaaga aaatgatttg gaatgtatgg ggatttgtta tgacccgtat aacgctaatt
    30241 cgcttatcag taaagctgaa aaagccaact acccaatgtt agaagtaaga caaggaacga
    30301 ttactctaaa cgttccgacc cgaactttta gagaacaagt ttatgaaggc aacgttattc
    30361 acaataaaaa tacgattctc acccatgcag tgaacaacgc tattttaaaa acggataaca
    30421 acggcattca gattaataaa tcaaagaaca gtaacaaaat tgatccaata gctgcattaa
    30481 tcaatgccta tgtgtttgca atggattact tcaccacaac ggaaggagcg aaagcagaca
    30541 atgaatttta tacaagtgaa gaattttctt tctaattaca ttcataccgt tcttttactt
    30601 cttggattgg tgtgtgtgtt ggttgctatc accttactaa caaatgtcta ctatggcttg
    30661 ttagcgctgg gcatagtgct tattggggta gcggtcatgc taaatacaga acagaaggga
    30721 ggttaaaaga tggcattttt taaagcgaga caaaatacaa cgggagatcc tttcctacaa
    30781 catgtggtat caatccaatc ggatgattac accaccagct ttacaagcgt tcgtgcatta
    30841 agaaatagtg atgtgtttgc agccgttcga attattgcta gtgatattgc ttcaagtccg
    30901 attcaattgg tcaaaaacaa tatgccacaa gctgataatg aactggtgaa gttactaaac
    30961 gagaaaccta attcagaaat ggatggttgg catttaaagt ttgctttggc ggtcaatatg
    31021 ttgctaaacg gtaatagctt tgcagagatt aaacgcaacg gtgaaaaggt agaagaaatt
    31081 cacttattac ctaactcaag tgtaacggtt actcaattag ataatggtac gttgtcttat
    31141 cagattggtg ataaaaaaag acgtgtgaag tctagcgata ttttgcactt caaatatttc
    31201 acccaagatg gtttaacagg attaccacca ctttatgcgt tacgtgatga actgaaaatt
    31261 caacaagctg gcaaccgcac attgcacaat ttctttactc gtggtgtcag tgggtcaggt
    31321 attttgaagg ttcataagtc agatttagac ggatcagcaa agaacgcaat tcgtgaaaag
    31381 tttgaagaag ccaacggttc aagtagtgga gataatgctc ttagaacgat cattcttgat
    31441 gaaacaatgg actacaaaac attagaaata aacaccgatg ttttgaagct tatcaattcc
    31501 aatgattgga acacaaaaca aattgccaag gcgtttggtg taccgattga gcgtttaggc
    31561 gttgaaaatg aacattctag caccgttcaa agtaatctcc agtatatcca aagtacgctg
    31621 attcattact ttaatgtgtt tgtgagtgaa ttagatacga aacttgaaac caatatccgc
    31681 tttaattccg atcagttact agagactgat cctgaaacaa aagtaaaaaa tgtattggat
    31741 caggtcaaag ggtcacttct cacgattaat gaggggcggt cgaaaatggg gctacccccc
    31801 atggatggtg gcgatcgttt actagcaagt ttgaacttta cgtatttaga tacgttggag
    31861 aaatatcaat taaaagaaca ggaaggagtt acaccagttg aataatgaag aagaaaagga
    31921 aaaacggctg acagaagaag ctgagctaac agccgattct cccaaagtag agaaagaaaa
    31981 tgaaaaacaa ccaacagacg gcaaaactat ttcaggctat gcgttgaaat tcgggcaacc
    32041 gtcaaaagat ttaggcggct ttgtagaagt gattacaccc gaagcattaa aagaggtgga
    32101 tttatcaaat gtgttcttat tatatggaca cgattattca aagccactag ctagtgtcaa
    32161 agcaggtacg ttgaaattga atgtcgatga tacaggatta cattttgaag cagagctaac
    32221 cgacacgacc tattcaaatg atgtgtatga gaatatctca aaaggggttg ttgattctat
    32281 gtcctttggg ttcgtgcttg gattagattc attcgacaaa aaagaagatg gcacaattga
    32341 acgatcaata gataaaatca aagcacttaa tgaaattagt gtcgtgaccg ttcccgctta
    32401 tgattcatca aatgtccaag taaataagcg ttcttacgaa tcgtttatga gtaacaacca
    32461 agcaaaacaa acaaacaata gcttagaatc cacttctaaa gcacaaaagg agagtaataa
    32521 catggaaaaa actttaatcg ataacgaaaa aacagaattg cgtgggtatg aagaatatat
    32581 ccgttcacaa ggcgaagtgc gtgatggagt cactactgta aatgcagcgg cagttgttcc
    32641 cgaagaagta atcggtgaag tctttgattt gaaacgttca aattataact tagctcaata
    32701 tgcaacagta aaaacagtat caaatggaca aggtaaatat ccagtagcaa ctaaccaaca
    32761 agcagtgtta gcaacaaaag ctgaacttgc tgaaattggt gatattgacg ctgaaatgtt
    32821 tacttcagtt gattataaag tagaaactcg tgctggtaag attgccttat caaatgaggt
    32881 tgtggaagat tcagcagtga atattgtaca agaggtcaaa gatcagttag cgaaattggt
    32941 agaaaacact gacaataagc atatcatgga tttattaaaa acattcacta agaaaacggc
    33001 tgctacgttg gacgatttga aacaactata caatgtggca ttagacccag cattaaataa
    33061 aatggtaatt ctaaaccaaa gcggatatta ccacctagat acattgaaag attcagatgg
    33121 acgttacatt ttacaacccg atgtgacagc acctagtggt aaatcattat tcggtatgcc
    33181 agtagtattg attgcagata cattgtttgc caatcctaaa gctggaacat tccctatgat
    33241 tatgggggat attgcacaat ctatctttgt tgctcgtaga aatcaagtaa cgactcaatg
    33301 ggaaaaattc gattactact cacaaggact tgcagtgatc gttcgcaacg attataagaa
    33361 aattgatcaa aatgcttcag tgtatattga gtttacgcca gttgtaacac caaaagtata
    33421 gaaaaatatt gggcggcggt ttatcccact gccttttttt cattaggaga gataaaatgg
    33481 taattttgga tagcataaaa aaaagtatgc ggatcgatca cactattgat gatgacttta
    33541 ttcaacaatt gattgataca gcaggcgaat atataaaaag tgctattgat agtagcgcaa
    33601 cggataaaga tatggataat tatcagcaat ttgatttggc ggtgtcatta cttactcaac
    33661 attggtattt gaaccgtcaa gaagccagca gcgaacggat accagtaacg gtacaagcat
    33721 tagtacaaca aatgagaggt gcttattatg ccaatcatta agaatgtaaa tgaattgact
    33781 gagagagtca agtttaaaaa gacaaaacgg gtaaaagatg aagatgggca gatggtggat
    33841 agtgaagaaa ctgtatttga atgttgggct aatgtgcgtt cacaaatgct aaaagacgtg
    33901 cttgctagtg taggtaccat tcttgaagga acgttgacgt ttattattcg atacgatcaa
    33961 gattatgaac taacaaacga tatgaaagta gcttggaaaa acaagagtta taaaattatt
    34021 tcaatcaatg aaggaacggc gtttaaagat tatacaacga tcatagctaa acagatttct
    34081 tagaatgatt acacttgtaa acgttgtggg tatttagtat aattaaggta gtaaatgaag
    34141 ggttagctgc ctgaattttg caagacttag ctagtcgaaa tctattgttg gactgaaaat
    34201 tgtaggtgtg gttgcaaaca tgctggacta agaaagatga tagatgatga acgttcaatt
    34261 ttaatacagg catgctagga ctgattggat ggttttggca agctgattgt gtagaaatca
    34321 aagaacacgt ctgttgtgga cgtgtttttt ttgttataat tcaaaagagg tgatttaatg
    34381 gacaaagcag agtttacaaa tttttattgg aagtattatc tacatttaga aaatgagttt
    34441 attaatacca cagattttgt gatgctcgat gagaataatt tcaaaacatt ctctattgaa
    34501 tatcaaaaac tactactagc gattggttcg gagtgtgaga ttattttcaa agaactttgc
    34561 ggatttgata gcagtagcaa taaaagcata actgatttta aagctgttat taaatctagc
    34621 gaattaatgt gtttggataa tggtgttagg gttatgaatt ctttaacatt gacttcacta
    34681 aaaccttttg gagatgggtg gcctgaagat acaccagatt ggtggaaaat atataacaga
    34741 gtaaaacatg gtcgttcttc aaattataag gaagcaaatt tggaaaatgt gttgtatgct
    34801 ttagcaagtc tatatttatt agaggaatat ttgcataaga aagtaatact agaaggtgaa
    34861 gtagacttta taagtccaga gtcaaatcta tttacgttat cttgggaaag aaaacattcg
    34921 tcgatgcaaa aagtgacgtt tgaaaaagtg gattcaaatt atgtagctcc actcattgat
    34981 tttaaagaac aagaagaaat ttaaaaaccc ccacggctta ttgaagtttt tgtatgccat
    35041 attgtatgcc atttggttta aatcgcttga aaaatagtga tagataactc taattcattt
    35101 agtcataaac gctgttttga taacctttat agttctttga tatgggtttc tcattcatgg
    35161 cggaagaaga agaatagaac aaaagaatga attaataaga tataaaaaaa gggattgtga
    35221 caaacgtctt gtcacaatcc ctttttccaa ataaacgatg ttcaatcagc tgcccctcgg
    35281 cattcgctcg aaaaacggcg aaatatgaag aactattttg ccatttgttt ctctaataat
    35341 caggtcaaaa cgttgacttc acagtctctt ccttaaacgg tgttctcctg ccaactcctc
    35401 ggtcacaagt cacaatattc aacaaacatg agaagctgtt ttttgaaatt gttccttgtg
    35461 actcggagct gaacggcagg ctcacgacct ctttcttaaa cggtgttcaa aagcttgcat
    35521 ctgcggtaat aagttcaacc aaacgaaaat tatgaggagc tatttttgtt tggctgttct
    35581 tattacttga tgcaggacag ctttttcaca acctcttttc gtttagcact aaatttcctt
    35641 aaaaagtaga aaagctttcg aagcctcgtt tgtttctttt actgtataat aaaagaaaag
    35701 agtaacaatc gctaaaagat ataaacaaga gaaaggaaat acaagatgat tggtctgatt
    35761 tattttgtgg tgatcgttct ggcgaacaca gttggcgcta tttccgggat gggtggaggc
    35821 gtgttgatca aaccgattct tgatcttatc ggcgcccatt ctgttgcagg gatttctttt
    35881 tactcaacag ttgcggtatt cacgatgtcc attgtttcga ctgtgcgaca agtatcaagc
    35941 gggaaatcac tgaattggca gattgtcggt tgggtatcta gtggagctgt tgttggagga
    36001 gtagtcggca acattgtatt cgaagttttt ttacagttat ttgaaaacga gaagcatgtg
    36061 cagctgatcc aaattttttt gacggtattg accttggttt ttgcgttctt ctacaccaag
    36121 catcatcagc caaaatttca tttgacgtca tggacttggt accttatatg tgggggggtt
    36181 ctgggctttt tagctagttt tttaggtatt ggtggtggac cagtcaatgt ttctttgttg
    36241 atgctgatgt ttgcattgcc aataaaagaa gcaacactat attctctatc tacgattttc
    36301 ttttctcaac tggcaaaatt ggtaacgatt gctttaacaa gtagctttat gcgctttgat
    36361 ttatctatgt tgttttatgt tatccccgct gctgttattg gaggtttgtg gggagcaaga
    36421 tttagcaggg ttttgtctcc aaaaaaagtg acctttattt ttcaagtaat tgtcctcgtg
    36481 gttcttttga tcaatcttta caatgctttc gtcatcttac aaacattagg agaatctaga
    36541 ctaacgcaag tcaaaatcac tgaaacatat tgttctaaat gaaaaaagga gtatactgtg
    36601 ataaaaaaat tcatttaaaa aaataaaaat tggctggtga tttggatgtt gcgggaaatg
    36661 cgtttaggag atgcagaagc actacgagaa atcaatgcgg aacaattagg atatgatgta
    36721 ccattaaccg ttacggtgag acaaatgaag aaactgttga aggagccaga aaaaaatttt
    36781 ttcttggtct atgaagatcc tacttctaaa aaagcagctg gctatgtaca agcggagtcc
    36841 tatgaatcga ttttcagcga tccgatgttc aatattatgg cacttgctgt gtctaaacat
    36901 gctgaaaaaa gaggaatcgg aaaggccttg atgactggcg tagaagaagc gaaaagacga
    36961 ggaatatcag caataagact taattctgca gaatacagag tagaagcaca ccgattttat
    37021 gaacgcatcg gttatcattc cgataaaatg caaaaaagat ttttgaaaat cctgtaaatt
    37081 tttatcaaaa aatacctggt catcaagccg atacttgatg atcaggtatt ttttttgact
    37141 aagaaagtaa ttgcatcaag aaacctgaga tgatcaaaac gatggcacca ccaagccgat
    37201 tgcccatttg agcaaaagca ataagttcca tccgattagc tgcagataag acagctacat
    37261 ttcctgtacc acccatcgag ttgttgcata agccagcagt aatagttgat tcgattggat
    37321 ataaaccaaa caaacgaccg acaaatcctg aaactactga aatcgcgata acacttgtca
    37381 aacataagac aacaaattgc catgtcaaag cagaagccaa tacatttaga ttcaataacg
    37441 caataccgat accggcaaga acagctgctg tcaagttttt gacaatcaag ttgttgaaca
    37501 tgatagctgc atcttcgtaa tattctggta ataggtttgc gattttacag ataacaacga
    37561 taatgatcat gaatgcgtaa gcatggactt taggaacaaa atagttacag atttgtccta
    37621 agatgaagaa agtcaatgat accatcaaac cgacacctaa ttgtggaatg gaaggtttta
    37681 catttctagg ttttccatcg ccaaggtcgc ctttttccat taatttacca ttaccgttga
    37741 attttggcat tgattgtccc gcacgagcaa ctaacgctgc accaatgata gctaggacat
    37801 ttgtcattgc tgtcgcagga atcaggcggg aaatgataga agaagcgtcc gtacctaaaa
    37861 catttgcata aatcgttgat aaaggtacag ctccggctcc aacaccacca gccattgcgg
    37921 gcaatgagat atataaaacg gaatttgcaa aaccatttcc gataagcata cctacgagtc
    37981 ctacggcaaa aaaggagacg accattgaaa taagtgcaac gggaataaaa cgaacagaag
    38041 ctttcatcaa tagattacgg ttcataccaa ggatgctacc agtaatcaag gcagcaatat
    38101 aaaagtctaa aaagcccata ttgctgacaa agttttctgt ggattttact acatactcag
    38161 gtaagatccc aaatgtagca atcgcggcag aggcaaagat cgcaaaaacg gagccaccac
    38221 ctaaataact tttgacgata gggatttttg ttccgataaa atgaaataaa ttaccgaaaa
    38281 tgaccaaaac agcgattggg ccaatcatat tcgtcggtaa ttttcctaaa gccattgcaa
    38341 tgatcaggac aaggaccatg atcaaataaa ggggcaaact tacgccggta atttttgttg
    38401 accaaaaccc ttcttttttc ttttcctcaa ctgcagttgc ggttgttgtt ttttgtgcca
    38461 tttttacaga tcctttctta ttctgtatcg tatgaaaaaa gccaaagaga agcggcaaaa
    38521 gagcagtagt tggctggctg ctgttttgcc gcagtcgctt ttttcttttt agacgtcata
    38581 caaagtttct gtatgttctt ttactataac aatcttaatc ttctaaagat ttatattcag
    38641 gaacccattt agcagattca acagcttctt tgatatccgt gatttcttca cgattcaatt
    38701 tttgtgcaac aactgatttt gcgacagttt cagcaatcgt ttgagagaat tcagtgattt
    38761 ttgctactgg aggcaagata gctgctcctg gttttgttac atcaacgatt ccgcctaatg
    38821 ctcgactagc ttgagaaatg atttcagcat ttactcgtgt agctgttgaa gcaatcaaac
    38881 caagccctaa acctgggtac atcaacgcat tatttgcttg accgatttgg taagttacac
    38941 cgttatattc cacatcagca gcagggatac ctgttccaac taaagctttt ccgtccgtcc
    39001 attcaatcaa atcttttgct tttgcttctg ccaattttgt tggattagac aaaggcatga
    39061 tgattggacg tggggtatga gccgccattt ctttcacgat ttcttcagtg aatgctccag
    39121 gttgggtaga agtaccgatc atgatcgttg gatggattgc ttttacaact gcttctaagt
    39181 ttgtcaattc atcagcatta gtgaattctg agcgtttacg agcgaatggg atttgaccag
    39241 gagtcaatcc ttttgtatct tcaaacaata aaccctgttt atctacttga tagaaatgtt
    39301 ggcgtgcttc ttcttcaggt acaccttgac ggatcatttc atctaaaagg atgtttgcga
    39361 tacctacacc agcagtacca gcaccaaatg tcaagatcgt ttgatctttc aattgctcac
    39421 ctgatatatt caatccacct aatacaccag ctagtacaac gattcctgtg ccttggatat
    39481 catcattgaa agtagtgatt ttatcttcgt atttttctaa gatcgttgca gcatttcctc
    39541 gtccaaaatc ttcccaatgt aataacaatt ctgggaataa ttcagtagct gattgaacga
    39601 attgatcaat gaattcgtag taagtttcgc cttctacacg agcatgacga ttccctaagt
    39661 ataatggatt attcaataat tcttcgttat tagtaccagc gtcgattgat acaggcaaga
    39721 cttgtgcagg attgatacca gccgcagcag tgtagaccat caatttaccg atagcgatgt
    39781 caacaccgtt cacaccccag tcacccatac ctaagattcc ttctgcatct gtcacaacga
    39841 tcaaacgaat gtcgcgtcca tctgctgcgt ttttcaaact tgctttgata ttttctggtt
    39901 cgtcgattga aagaaatgca gcatcttgtg gtttcaagaa aatttcgttg tattgttcga
    39961 ttgaatccgc aacgacagga tcataaacga caggcatgaa ttcaactaaa tgttcgccca
    40021 tcaatttata aaacaatgtc cggttcgtat tgaatagatt cattaagaag atacgttttt
    40081 ccaaatcggt ctgtttgctt aagtattgac cgtaagcttg gacagattgt tgttccaatg
    40141 tttggacagt acttggaagc ataccagtga ttccgtattt tgcccgttct tcttttgtaa
    40201 aagctgttcc tttatttaga aaaggattat ttaataagtt tagccctgta agcatgaatg
    40261 attcctccta agttttaata caaacgaagt ataggagtca gatgaggata tagtcaaaaa
    40321 gagcaggtat aataaatttt atttatatga gtaatagagt caaaagaaat caaaatagcg
    40381 gtatttgttc tttttatatc aacaatcctt gcttgattac tatgcgtatc tcttatatgc
    40441 taaagaaaga aaagtagaag aataaaggat atgttagata gataaataga atctctgaag
    40501 aataaatcac gtgatcgtga cgataaaata cacttacgtc aggtgataaa aaatacataa
    40561 gtagaaaact aagaggagga acagaaaatg aaagaagttc aattgatcag aaaaagcgaa
    40621 ctatcagaag gtggttgcaa tgcatgcggc gtagtagaag caacaagcta tacattaaag
    40681 cttggtgcca acaaagcgat aatctctgag ttgacagtag gcggtcttgt ggacagtctg
    40741 gcgcttgctg aaggttttat tggagaagat atttatgaga tgttttcaga aatccgtcag
    40801 ttaaaaaaag gggaaaactg catagaggtt catcatgaga gcccgaatgt gagattcaaa
    40861 cgtggtgata atgagatgat cttcaataat catgtgtccg atcacaccga gctatatgga
    40921 atcgtgaatc aaatactaac tgagcttttt ggattgggac cttatgcgtt caaggaagaa
    40981 aacggtaatc caaaattaaa cgaagaatgg caagaaacga ttgaaataca aagaaacaac
    41041 ccgcacttat ttcaataggc atccacagta tttcgtaaaa gggactttga cacgactttt
    41101 gtcaaagtcc catcgttttt tatctatttg tgttctaaac atttctttca gagtagtaac
    41161 aactggaatg actgaaatgt aaacagatta tttgcctgta tcaatacgga agagtaatat
    41221 aaagtgtgta aacgctatca tattattcat tcaatttttt atagagggaa ggcattgaaa
    41281 tggaaaaaac gtatcaagca ggtacaaatg aaggaatagt ggattttatc aatatggaag
    41341 atttagaaat agccgcttca caagtgattc cagctggtgg ttatggttac atcagcagtg
    41401 gtgctggcga cttatttact tatcaagaaa atgaacgggc attcaatcat cagctgatta
    41461 ttcctcatgt attaaaagat gtagaattac ccgatacaac tacacatttt gacaaagaaa
    41521 cgctgactgc accaatcatc atggcaccag ttgctgctca tggcttagct catgtgaagg
    41581 cggagaaagc ttctgcaaaa ggtgtagcag attttgggac gatctataca gcaagttctt
    41641 acgcttcttg tacattagaa gagataagag aagcaggcgg ggagaaagca ccgcaatggt
    41701 ttcaatttta tatgagcaaa gatgatggga tcaatttgga tattcttgaa gtggccaagc
    41761 gtaatggagc aaaagcaatc gtattgacag cggatgcaac agttggcgga aaccgtgaaa
    41821 cagaccgcag aaatgggttt accttcccac tgccaatgcc gatcgttcag gcttatcaat
    41881 caggagtagg ccaaacgatg gatgctgtgt acaaatcttc caaacagaag cttagtccaa
    41941 aagatgtaga atttattgct gctcattctg atttgccagt ctatgtgaaa ggtgtccagt
    42001 cagaagaaga tgtctatcgt tcattagaat ctggtgctgg cggaatctgg gtatctaatc
    42061 atggtggccg tcaactagat ggtggtccag cagcgtttga ttcgttgcaa tatgtggcag
    42121 aagcagtaga taaacgtgta ccaatcgtgt ttgacagcgg tgtacgacgc ggacagcatg
    42181 ttttcaaagc aatcgcatca ggtgcagatc ttgttgctat tggcagaccc gttatttatg
    42241 gattgtcttt aggaggaagt acaggagtcc atcaagtgtt tgatttcttt aaaacagaat
    42301 tggaaatggt catgcaatta gctggaacac aaacagtaga agatatcaaa aaaataaaat
    42361 tgcgtgagaa tcgttttatt taagaaacaa atgacgaaaa aaataggagt gcggcagatg
    42421 atgccgtact cctattttta tagttcaagg atgtcactaa tagaataatt tgaaacgaaa
    42481 aaataaaatt gaaatatttt ttcatactta ataaaaaagg aagaatattc atgtaaacga
    42541 ttttattgtt tttttctctt ttatacaaaa agggtcataa tttcaagtaa gcggatgaat
    42601 tcatgaggat tttttgcata ctgtctctac tatacttagg tcactaagaa aaaggagtga
    42661 tttattatga aaaagaacat gattgggaca ttattacttt caacacttct tctaggcggc
    42721 ttggcaacac cagcttttgc tgagggtcaa gcgacttcaa aaggagatat tacctttact
    42781 gaaccaacaa ataccgtgga gcctcttaac cctactgatc cttcaaaacc agtagagcca
    42841 gcagatccgg aaaatccagc aactggccag acaggtcctt taacactgga tgtagttccc
    42901 gaattgccat ttggtacaca cgagattgaa agcggaacaa aaacgtatca agtagacgct
    42961 tcaaaaaacg atacacctta tctccaagta tcagatcgtc gaggtgtagg tgcagatggc
    43021 caagcacaag ggtggaacgt gacagtttcg gtttcagatt ttgtaaacgg ttcacaagtt
    43081 ttgcaaggcg ctgaattaga ttttggaaca tccactgtta aaagtacgtc agataacgaa
    43141 tccactggac caactagtca aactgtaact gggttgagta aagcaagtgc agcgacacca
    43201 atatttacag cagcaaaaga tcaaggtctg ggaacatggc tttctgttta tgatccagca
    43261 aatatcacac tgaaagtgcc gaaagcagca gctggaacat tcacggctga tttgacttgg
    43321 aacctcgtgg ctggcccagt agcatagagt atgaaataaa ttcaacaaac tgcggtgaaa
    43381 atactatagg tgaaggattt tttaccgcag tttttgttga aaggatgtgg tggacaatga
    43441 atcaaagtaa acgactgttt gtttcgtttt tttctatttt aagtctattt ttcatttttc
    43501 cgtcaatcag ccaagcaaag gattcagcag gagactttgg aatcaaaccg gtatttccag
    43561 agaaccaaat agataaagca atcggttatt ttgatttatt agtggcaccg gaacaaaatc
    43621 agacactaga agtaattatc agcaattctt cagatgaaga acgaacattt gaggtctctg
    43681 tcaatccggc ggtaacgagt gatggtggaa cgatcgatta tagtcaaaaa aacccaacgt
    43741 tagatgagac attgccgttt gatgtccgtg acgttttgct cattgcgaaa aaggaaatca
    43801 atgtatcagc acatgcagaa acaactgtac ctatagaagt gaaaatccca gcaaaaagct
    43861 ttaagggacg tgtattagcg ggtattcatg tttcacctaa agaagaagct gaaacagaaa
    43921 atgctacaga aggagcacaa atcaaaaatc gtattgctta taatctcgca gtcgttttac
    43981 aagaaagtca agagacgata gaaccggatc tgaaactttt atcaggagat ttggacgagg
    44041 tcaacgcaaa gccaactgtt cagcttcgtt tccaaaatcc tcagcctagg attatcagca
    44101 atttgatatt tacgagcaag atcttttatg aaaatcagct ttatattgaa aatacgtcta
    44161 atgcattttt agttgcacca aattcgaatt ttcacttgaa tcttgattta gctggtgata
    44221 aagcaaaagc cggcgattac cgcgcagaaa tcatagcaaa atcaggcgac agtaatgaat
    44281 ggcgatttac acaaaacttt acgatcaaaa aagaaaaagc acaaaaagta aatgaaaatt
    44341 ccgtttttgc agtacaagaa caatctttcc catggcttta tgcaggattg gttgctgcag
    44401 ttctagtgtt atggttgatt ttgctgtttt tgtgggtcca caagaaaaag aaaaaaggag
    44461 aaacaacatg atgaggtgat ttcgttgaaa acatcgatct tattgggagg gattattgca
    44521 agtttgctgt tcttcagctg gcaagagcca gtccaagcag ataccaaaag ttcaggtacg
    44581 attacatttt atgatctaag tccaattccg catccaagtg gttcagtcaa tggcgcatca
    44641 aaacagcaga cacagctacc gatttataaa gaatctaatc aacatggcgt attcccggag
    44701 acgaatgaac aaaagatccg ttttctttat ttgatcattg gtatagaatt atggcttctt
    44761 gcgtggttgt tgttatggag aagaaaggaa aaggaggatg aacatgttgc tacaaaataa
    44821 attttcattt tttcgctcct tcttttttac ttcgcttttt gttttaagta tatttatctt
    44881 ttcaccttcg gcagaagctg ttggagcaac gcctcctgcc atttcttatg atccatacac
    44941 gtatgaaaat atcgtacctc caaatggtgg acgtagtgca gtcaatggcg ggaagcttgt
    45001 ccaactaact ggggctaacc aattgcctaa attgactgct acttatttga acgatggttc
    45061 aaatgatcct tggaaaggtg gcacggtccg ttttcattgg gaaagccatg tgaaactaac
    45121 aaatgtactt gatttggtga atatcactgc acaaggattt gcatttgtgg cgatcatcaa
    45181 tttgccggaa catgtatcaa gcagtgatgt attaaaagca attgactgga acaacgccta
    45241 cttgtatatt gccggtgccc ccatcaaggt tactagcgga agtttattat cagcaggaag
    45301 ccataccttg cgttttggga tggggtcgtg ggatacaaat actctattga cagatattat
    45361 tgctattatt acgcgaggcg aattcaacgt ggacgatatc ccgcttcaat ttgatgttac
    45421 agctaatgtc gcgaagatga cagaaaacgg agataaatat gatacgagtc caaacaaaat
    45481 tttgaccaag ggtaaattac aaccttctat gtctaaaaag gccgtttttt ctgttgattt
    45541 ttatgattcg aataatatta tccaagatcg tatgttcaat tcgattttag ctccagctgc
    45601 aggtagattt tatcctaaat taactggcgg aaacttgaat ccaggagcat atgcattttc
    45661 tgcaagtgca gagataaata cgtggaatag ttacatctca ccaagtgatt caacaggaaa
    45721 atataataca tttgctgata ccacagaata cgtggatgga aataaccaga accttccagg
    45781 ctctaccaat agtcggacat tgacgatggg gctgactgaa ggacgttttg atcagttgcc
    45841 atttagtcgc tttgatcgcg tagtcaacta ttttacagga aaaaacgtta cacaaggagc
    45901 aatactgact catactccag caagcacaag tggattgaat cagacagcca atatcgtgta
    45961 cagtgggaaa gatgcgcaag gcggattgct ttctcctgtt gctttaaagg tattggagca
    46021 gtacaagcta gacggaacgg ttttaccaac aaacttaaca gccgatagtc agtggggaaa
    46081 gctcctttct tctgcatcgt accaagtcac ggccaattgg tcagcaactg aactaaaaaa
    46141 gggttcgatc cattacaggc tttattcgaa aggaacccaa aaattagcga caggatggac
    46201 agatcaactt ttccaaacga tccaatcaaa taacgggggt gtaaatacag ctacttctac
    46261 actacctgca ttggcttcag ggcaatatta ttttgattat cgcttggtgg acgatgtact
    46321 tactaacatg tatccgtctt ttgcgtacaa atggcagtct gaacaagctg gaatcaccac
    46381 tcttcctcaa ataacagtgg ctaattttcc atctgtgagt gcagatagtc agctaaaaaa
    46441 ccttagcaga caacctgaga caggagatcc cctgtctgct ctatcaggag atacgattca
    46501 agaaaatgtg acattcacgt taacaaaatc tggggatgcg ataaccgaca aaaaaatcac
    46561 gatctcactt cctgaaaata ctacttatat caatggttcc ttaaaattaa atggtacaac
    46621 tatcgcagat accggcattc aacaaggagt ttctgtccca gcagatctat tgagcaaaat
    46681 aggagatacc attcatctta cttacaacta tcaattaaat actgtagata cttctttaca
    46741 atccgtcagc atactgacaa aggcagctgt actttccagc aatattacat tagcagatgg
    46801 tgctaagctt cctaacccag ttgtccaaac atctgctaaa acaattcttg tccccaaaca
    46861 agaattaaca ttagttaatg taccagatga ttttacattt ggtaacgatc tccccaaacc
    46921 gttgaagaca agttattatg aatcaaaagg cgatttttct tttgatgtgc gggatactcg
    46981 gcttccaagc acgtctcctt ggcaactgac aggtacattg acttctttat ttaagaatga
    47041 tcaaggtcaa gaattaagcg gaacaaaatt atacttcaat cattctggat caaagcaatt
    47101 gattcagcaa ggtcaaaaca cgttgattta tgagagtgat ggaacagcta aaggagaggt
    47161 tctcgttgac tttcccgata ccgatggttt actcttagag gtaaatagca gtacgaatgc
    47221 tcaacctggc gcaacgtatc aaggcatggt cacatggaaa ctgacagctg ggccaaccag
    47281 ctaagtgatt agaatttgta tggatctgtg ataactgtca cagatcctct ttttcaagga
    47341 tgagaaggaa acttctgctg ttaaaatcag aaatgcttga aggagtggac ttggaacttt
    47401 tcagtttgct tgaaaaaaat gaacaacggc aaatcaaact tttccaactt ttattagagg
    47461 aaaaaggaga ggtttccgtt aataacgtac ttacccgctt atcagttgat cgggctacct
    47521 tgaaagaaga tctgttttat ttacaagcta acttggaaaa tatcaaacaa ttggaaattg
    47581 ttatccaaga agggaatatt ttattaatca gacatggaaa tatagcagca gtcgatgttt
    47641 attatcattg ttacttgcgc tattctacaa aatatcagat acttctttat ctgttggaaa
    47701 atggctcatt tgatcggcag aaacttgtca tggaacttaa tatcagttcg gctactttgt
    47761 ctcgcagagt gaaggaatta aatgattctt taaatgagtt tcatctgaaa ataaaaagcg
    47821 ggcggctgac cggtccagaa agtcaaattc gttattttta tttccaatta ttttggtttg
    47881 gacgtcccta tcttgaaaac aaaaaagaat acagtgattt atcaggaaac acttttttag
    47941 atctgctgca aaaagagttt agttttgcta ttacagaaga aggacgattg aaatttgaaa
    48001 tatggctttc cattatgaag aagcgaatgc gctgtacgaa aaaatccaaa ccagattata
    48061 gcaatcttcc tgttggattg tttcaaacga cacaattttt attggacctc catacatttt
    48121 tgacccgtta cttctttcaa tatgcctttc cttggaatca aaatgaaacg ttggtttttt
    48181 atcttttcat gatcagtaac tttacattag atacacataa ctcgcatgtc caggagtttt
    48241 tgataagcga aaaatacaaa gacgacgtag tagctcaatt gaatcgaacg tttaaacaat
    48301 cgatagaaga atatttctct ttttatgttt ttccagaaga gatttcgcaa aagattgcgt
    48361 tgacagtgat gcaaaatcac gctcattttg cctattttag aggatggatg aatatttttg
    48421 gccaagaagg attaaaacag cggttaactg aagtagaaga taaacaattc ctggttttat
    48481 gtgaaagatt ggtcagacaa acatttgcta ttgttgattt tactgaagta gacgaggaaa
    48541 atgcccgctt tgaattattt gctcgctatg catctatttt acggacgctg atcaagcagt
    48601 tagaattacg tctgcaaatt gcttatgatc ttccttatga aaggctaatg gcggatatcg
    48661 tgaaagaaat catccaggaa caattgctga atacgatcaa atatgattta gtcgaatacg
    48721 agaaagaaaa gcagtatgat atcattttga ctagccaatt gaaagagtac ccgtcacaga
    48781 agtccgctaa agtttttgta ttcactagca acgaatataa ttatgatttc ccctatttga
    48841 accaattttt aaaagaatgt tatttagaaa aattgaattt aaggatgaat aaaacatgaa
    48901 aatcgtgatc attggtgctt cccatgcagg catcacagct gccctaaatc taagaaaact
    48961 tcaaccgaaa gcagaagttt tactgatcga tgaagatcat aaagatggac taggctatgt
    49021 ttcaaatgga atcaaccttt atttaaaagg aaagatacgt agtttagctg aagttgccca
    49081 taacatgcgg actcttcaag aaagtggggc aaaactgatc accgaatgga gagtaactga
    49141 acttgatcca gacaaacatc agctcatcct cgcatccaaa gaaggaaaaa acgagaccat
    49201 aacctatgat aaattaatcg tagcgacagg ttcctctcct gtcaccttgt ataaacaaat
    49261 tgaagctgaa aatgtctaca cctataaaaa tctagtgcaa tctaagcaag tacttgccgc
    49321 tttaaaagaa gcaaaagaag tagtgatctt cggtgctggt tacattggat tggaattagc
    49381 agatgctttg agaaataaag gatacattat tcatctagtt gattatatgc cgaatgtttt
    49441 atcaagatat ttcgataagg atatgatcaa cagttttcaa aatcagctgc aaactaagca
    49501 aataaatttt tatccaaatg aattcttgat cgattggaaa aaatcagaag agaaagtagt
    49561 atccgtacaa cttctgtctc aaacaataaa ggcagatatg gtcatttttt ctgcccaaac
    49621 tcgtcctaat acgacattgt taaaagaaaa agtggctttg tatgaggatg agactgtgat
    49681 agtcaatgaa tatctgcaga caagtgatcc ggacatctat gcgattggag atatcgtccc
    49741 agtcagtttt gacaaaaata aacggcatct ctttttacct ttagttactc gagctgtaca
    49801 tatggcaaga gcagtagcgc taactttgag tggtcagcca accgcttacg acctcagaca
    49861 aaagataaca gcagcagtca ttatagacta ctttttagga actgtagggc tgacagaaga
    49921 tgaagcgcca ttcttggaac aaaataccgg ttcgtgttca ggagaatttg atctatttcc
    49981 acaatacgac gaagaaaaca aaacagtaaa tgcaaagctg atctaccatc cggatacatt
    50041 agaaataatt ggcggacagc tgataagcca agaattctta ttatcagatt tgaacctgct
    50101 tgcggatatc gtgaaacaca aaactacgat tccacagcta gcagttgagg attttggatt
    50161 tctgtctgaa tacacctctc gttttcacta cctcaatgag ttagctttta aagtactagc
    50221 taagagagca aatagcaata gagtagataa aagactgtga gaaatatcac ggtcttttat
    50281 tgtgtgggga tataataaat attaatcaat cgagaataaa aaattcatat aatgaaatag
    50341 cggaagaatt ttttgagcat aatattcgcc aaaaatttat caagtgataa aattgttgta
    50401 taaaatgatt atttcaggag gaggagttaa atgtttttag cattaaatga aattatgcat
    50461 tcaaagttac gttatgcgtt agttgcaggg gtgatgtttt tgatcgccta cctggtattt
    50521 tttttgactg ggttagctta tggcttagct caagataatc gaacagcagt cgacaagtgg
    50581 gaggcagatt cgattgtgct ttcgaaagat gcaaattcaa atctagggat gtccatgatt
    50641 actaagaaga tagcagaaga agtcgaaggt gggaaagtgg cgtatcttgc ccaaacacct
    50701 ggagtcgtga ctagtaaaga cagtacagaa gaaggaaaaa tcaatgttag cttcttcggt
    50761 atcgataaaa atcaattcat catgcccaat cttgttgaag gaaaagcttt tgataacgat
    50821 gatgaggcag taggcgatat tagtttgaaa gaagaatatg gtctagccat aggagataca
    50881 gttaagttat ctggtagtga caagacgttt aaactaactg gctttacgga tcatgccaaa
    50941 ttcaatgtct caccagttct ctatacaacc atcaatgctt accaagaaat ccgcttcgaa
    51001 aaagaagata caagtgaaaa tgcacggatt aacgcaatag ttgtcagagg taaaatcagt
    51061 aatttacctg aagatttaga acagatcaaa atttctaaat tcatcaatga attacctgga
    51121 tataatgcgc aagtattgac ttttggattt atgatcggat ttttgatcgt tattgcggct
    51181 attgtgatcg ggattttcat ttatgtactg acgatgcaaa agattaatat ctttggtgta
    51241 atgaaagcac aagggatcac aggaggattt attgcgcgtt ctgtagtggc acaaacattc
    51301 attttatcat ttgttggtat tcttcttggt ctattaggaa cagtgggaac atcccttgtt
    51361 ctacctgatg cggttccatt ccaaagcaat tggctgtttt ttggcgtcat tagcttgttg
    51421 atgttagtag tagctgtgtt aggcgcacta ttttctgttc ggacaatcgt aaaaatcgat
    51481 ccgttgaagg caattggata agaaggagga agaacatgaa agcaatagaa tttaaagaag
    51541 tagaaaaaag tttccaagat ggcgaccaag tagttaaagc attgaaagaa acaaccatga
    51601 gtatcgataa aggggaattt gttgcaatca tcggtccttc tggttcaggt aaaagtactt
    51661 ttttgacttt ggcaggcgga ttgcagacgc ctagcagtgg ctctgtattt atcaatgatc
    51721 aagaattcag taatcaaaaa gaaagcgaac gcgttaaact acgttttaaa gaaattggct
    51781 ttattttgca agcttccaat ctggttcctt ttctgacagt aaaaaagcag ttattattag
    51841 tagataagat taaacatgaa catcgtcaaa aagaagcaaa cgaattattt gagcagcttg
    51901 gcgtggataa gttgatcaac aagtatccag aagaactatc tggtggagaa cggcaaaggg
    51961 tcgcaatcgc tcgtgcattg tacaatgatc cgtccattat tctagcagat gaaccaactg
    52021 ctagtttgga ttcagaaaag gcacgagaag tagtcgatat cttggcaaaa gaatcaaaag
    52081 acaaaaataa agcaacgatc atggttactc acgatacacg gctgattgac aaatgcgata
    52141 gaatatttat gatggaagat ggtgtattga aagaaaaaga ataaccaaaa agcaggtgga
    52201 aaaatggtcc atcgatacaa caaagataca cagcaaaaaa ttttgaaaga agcgactgac
    52261 ttgtttatgt ccaagggata tctcggcact tcaacaagag aaatcgcaca aaaagttggg
    52321 atcacccagc ccaatctcta tcattatttc ggtgataaag aaaaactata tacggcagtt
    52381 ttagaaaacc acttaaaaga tgttggaaaa gctttgagag aaatcgttca aacaagcgaa
    52441 acgggatttc aagtaacctt gacaaaaatg gcgcagtttt tgattgagac acatctggtc
    52501 gatttgtttc tgatgcttca cgatcttgaa agcaatcttt caaaggaaac aagagatcat
    52561 cttttctttc tatggaagaa aaattatcgt gaaccttttg aagaaatctt ttcagcaaac
    52621 caatctgtgc taagaaatgg gatttcaaaa gaaatcgcag caaggcattt tttcttagtg
    52681 ttagcacctt acatcactcg gtcgaaaaga cctgtggaag aaccgctaaa tgtggcgcaa
    52741 ttgatcgatt tatatttgaa tggtgtatta ggagaagcgt aaagctgtta tatagggaga
    52801 aaatagttag gtgaagaagc aagatatgac gaagatcgtt atatcttgct tctttatata
    52861 ggtagttttt cataaagaca aatttgttat tctctcatga ttatcagggt atatttttat
    52921 ttattatgtc ggtgttccag gaagtgtttt aatttaataa cgaagaaatt aattgtttgt
    52981 agaatgaagg aaactattta ttgggtagat gaatcaccac gaatagtcaa aaggagattt
    53041 caggatatgc caaaaatgaa aaaaatcatt ttagcagtaa tgttattttc tacggttata
    53101 tcttttacag cccctttttt gcttacttaa gctgatttta agttttggcc cttagtctgg
    53161 atctacgagg tgagagtcaa gaatgaaaaa aataattgga gcttttgtat ttgcaatcat
    53221 tatcattatt atctgttttc aaatagatgt ttttggtcaa aaaaagatag ttggacaaac
    53281 ggtcagcagt acgaacagta cggttacaaa gacaaaggaa tcatttgatg atacagaaca
    53341 agagacatta atcaaaatcg gaaaaaatga ccgtacacta tatacagatg actcgctaac
    53401 taccccactt gcaactataa acggcggaga gctggcggag tttctttctg aaacaaaaaa
    53461 tgcttatcag atcaagacaa atgatggcta tactggatat ttagccctcg aagatggaac
    53521 caaagtcaca aagaatatac aaacaaaacc ggaagagcta tctgatgcag tgattgtatt
    53581 agatcctggg catggcggaa atgatactgg ggcattaagc aatgatgaac aaacagaaga
    53641 aaaagatata acattaagta cagccataaa agtaaaaaag gcgctagagg atgctggagc
    53701 aacggtttat ttgacccata ctacagatga attagtacag cttggagata tatgcgacta
    53761 cagtgaagaa aaaaaggcag atgtctttat cagtttacac gcagactcta cggaatatgc
    53821 gaatgaagca actggaatca cgacatatta ttactatgga caagaggaaa cattagcaca
    53881 gacaattgct gactccttca ctgatctgcc tctggattca agaggaatct ccactgggaa
    53941 ctatcaagtt cttcgagaaa atcttcaacc ttctatttta atcgagatgg gttatatgaa
    54001 taatgatagt gatttaaagg aattagtaac agacagttat cagcagcaga ttgctgcaag
    54061 tttgacacaa gcattgacca cttattttca gtaataaata agcccagcca aacaaaaata
    54121 gctcctcata tttttcgttt ggccgggctt attatcgcag atgcaagctt ttgaacaccg
    54181 tttatttttt tagtagcttc aaagcttttt ctgtatttgc aaagtgaagt ttggcatatt
    54241 tttcaagcat aggcatgccg cctttctcca atagttttgc cgctacttgg tcagatttcg
    54301 ttccagctcc tgatggaagg gtgattccag cttcagctga tgctttgtgt aactcttcca
    54361 aaaagctggc acgactgatg atagaagcag cagcaacagc taaatgatat tgttctcctt
    54421 tagtaacgaa gtacagtttt tcttgtaatt gatttttttc taaacgcgca tattttttaa
    54481 aatttgcttc cggcgtaaac tgatcgatca aaatcgcttc tggtttttct ggctcgattt
    54541 tttttagcag caaatggatc gcttgattgt gcaaagcgac tttcatccga acggcattgt
    54601 attttggttg gatctcattg tatttttctg gagataagac aagcagttta taggggatgg
    54661 ttttttttaa gatgtcagca agctggatga tttggctatc ttttaactct tttgaatctc
    54721 taacaccaag tttacgtaat tctgcaagct gatcacgttt cacataagca gcacatactg
    54781 ttagcggacc gaaatagctg ccatttccga cctcatcact acctaaaacg gataattgac
    54841 tgatattttt tggcaaagaa gaggctgttt ttgctggctt ggcttgttta tcctgtgcct
    54901 ccccccattt atcagcttct attgctgcat tcgtaccttg aaacatcact tttccggatg
    54961 tataagcggt aatggtcgtc ccgtcttttt ttgcagcaaa gctagtataa ggaatctgtt
    55021 tatttaacaa ataagagcga tagtatgctt tcatttgact aagttggtcg tttgttgctt
    55081 tgataatgac gttgctcata aaattctcct cgtttttata cataaaacta taccgcaact
    55141 cacgactttt cgttttctaa gagattgcga gacatagcat ttttttaaag tttatcatat
    55201 aatagttaag tatgtgaaaa atatttgtgg agaacggtga aagaaccaac ttcatggtac
    55261 actaaataaa actttcatca aataggagga aatgattcgt atggcgcacg aaaaaacacg
    55321 ctacaaagcg gtgattgcca accaaacata tactattatc ggacgggaaa ccaagcatca
    55381 tatggatatc gtaacgaagc tgatcaatga acagttagca gaattgaaac aattatcacc
    55441 acaaatggat aatgaacaag cagcaatctt gatggctgtc aatgcgcttt cggatcaatt
    55501 gaagaaacaa gaaagaatct tggagctgga agaagaaaca gcagaattaa agaaaaaaat
    55561 gatcaaattt acagagcttg aaaatcgtgt gaaacgcatt gaagcaatcg agaacgaagc
    55621 tcgggaagta ttgaaagaaa atggtcaagc agatcatacc attaaaaatc atgtggaagc
    55681 acaacagatt ttaaacgaga aacgaaaagg acaaattaaa caaaaatctt ctaattaaga
    55741 tccttttatc aaaataagaa aaatttaaaa aaagttagaa gagaaaggaa cgtagcatgc
    55801 tgagtttgct gattttattt ttattgctaa ttgcgttttt ttctggagca cgtcgcgggt
    55861 ttgctttgca aatcatattc gcgattggat atgtattgtc atttattgct gcccagcatt
    55921 tttacaaacc attagcaagt catttggaat tatacattcc atacccagct gtcacgccaa
    55981 catcaaagtt agcatttttt gatcaggtat ttgcctttca cctagatgaa gctttttatg
    56041 caggaactgc ttttctgatt attttgctaa ttggctggct gcttacccga tttgtggggg
    56101 tttttgtcca tggattgacg tatgtgccga tcttgagaca ggtagactgg attgcaggag
    56161 gcatcctgtc actaatcatg gcttacgtta ctatattttt gattttgcag ttacttgcct
    56221 ttgttccatt agatgtggtc caaaatcaat tcggcgagca tagtttcgct cgctttatcg
    56281 ttgagagaac gccatttctt accaacaaga tgtatgagct ttgggtaacg aatattttga
    56341 attaaggaaa atagtgctgg aaaatatttc gttttttgta cagagtagat tatttaagaa
    56401 ggctgcgtag cgtatgtccg gcacagctct tttttcatag tgaaagataa ggtgataaaa
    56461 tgaataaccg aatccttgaa acattggaat ttgaaaaagt caaacagatg gtcagacaat
    56521 ttgtagtgac tgcacaagga aaagaagaac tggcagaatt ggtaccagtg agcgaggaac
    56581 aaacgatcac aaactggctt caagaaactg aggatggatt gaaagtgcaa cgtctgcgag
    56641 gcgggatccc tatacctaaa cttgaaaata tccgtcccca tatgaaacgg attgagatcg
    56701 gagcagactt gaatggagtg gagcttgcac aagtttccag agtattgtct acgacaagcg
    56761 aattgaatcg tttcattgat gatctttatg acagtgaaat cgaatttgca cgtttgtata
    56821 tgtgggcaga tcagttagtc acgatccctg ttttgagccg ccgtttaaag gaagcaatcg
    56881 atgaagacgg acgcgtgact gatgacgctt ctcctgagtt aaagagcata agacagaaca
    56941 ttcggcgaag tgaacaagct gttcgtgaac agttagatgg gatcgtccgt gggaaaaatg
    57001 caaagtattt aagtgatgcg atcatcacca tgcgaaatga ccgctacgtt atcccagtca
    57061 aacaagaata ccgcggtgta tttggcggtg tagtccacga tcaaagtgct tcaggacaga
    57121 ctttatttat tgaaccaaaa caagtggtgg atttgaataa tcgtttgcgt caataccaaa
    57181 tcgctgaacg aaatgagatt caacgtattt taagtgaact ttctgctgaa cttgttcccc
    57241 atcgtcaaga aatcatccac aatgcttatg tgattggtaa aatggatctg atgaatgcaa
    57301 aagcacgatt tggtaaagaa gtaaaagcta tcgtgccggg aatcagtgaa gacaatcatg
    57361 tcgtcttgaa acaagcaaga catccactga tcgatcagga aaaagtagtt tctaatgaca
    57421 tcacaatcgg aaaagactat caagccatcg tcattacagg acctaacaca ggtgggaaaa
    57481 cgatcacgtt gaagacttta ggtctgttac aactgatggg gcaagcagga ttaccgattc
    57541 ctgcaggtga agaaagtcaa atcggtattt ttgaggaagt atttgcggat ataggagacg
    57601 aacagtcgat tgagcaaagt ctatcgacct tttcttctca tatgacgaac actgtagata
    57661 ttttatcaaa agtcaatgaa aaaagtctgg tattatttga cgagctcggt gcaggaacag
    57721 atccgcaaga aggtgctgct ctagcaatcg caatcttaga tgatcttggt aaaaagtctg
    57781 cttatgtgat ggcaacaacg cattatcctg aattgaaagt ttatggatat aatcgggcaa
    57841 atacgattaa tgccagcatg gagtttgatg tggatacatt aagtccaacg tatcgtttgc
    57901 tgattggcgt tcctggacga agcaatgcgt ttgaaatctc tagccgatta ggtcttgata
    57961 cagaagttat tgatgaagcg aagcagttga tgaatgatga gagccaagat ttaaacgaaa
    58021 tgatcacaga tttagagaat cgccggaaaa tggcagagac cgaatatctg gaaatgcgtc
    58081 attttgtttc tgaggcacaa gaacttcacg atgatttgaa agaagcttac agctatttct
    58141 ttgaagaacg tgaaaaagaa atggaaaaag caaagaaaaa agcaaatgaa gtcgtgtcag
    58201 aggcggaaga aaaagcagaa aaaatcattg ctgatattcg taaaatgcaa cagcagattg
    58261 ggcaaggaaa tgtgaaagag catcagttga tcgatgcaaa gacccaatta gcaaatctac
    58321 atcaagaaga aactttgaag aaaaataaag tattgaagaa ggcgaaagaa caaaaaacgt
    58381 tgaaaccggg agacgaagtg ttggttacga cttacggcca aagagggacg cttttacgta
    58441 aaaacgggaa tcagtggcaa gtagaaatcg gtatattaaa aatgaatgtg tccgaagacg
    58501 agctgacgcc tgttgctcct caaaaagagc cgacacaacg agttatccat gctgtacgat
    58561 ctgaatctag tagtcacgtg ccgaatcaat tggaccttcg aggaaaacga tacgaagaag
    58621 cgctaagtga ggtagatcaa tatttggatt ctgccattct agctggttat cctcaagtga
    58681 ctattgtcca cggaaaagga acaggcgcac ttcgcaaggg aattactgat tatcttaaaa
    58741 accatcggag cgtcaaaagc tttgagtttg caccggcaaa ccaaggcgga aatggtgcga
    58801 caattgttaa atttaagtaa agcttactaa aggtaagcag atggttcgct atccaagtat
    58861 agaaatgcta tactagtcat agattttaaa aatggaggtc tttgatatgt cacaagtaat
    58921 tacagataag acatttaatg aagaaacaga taaaggactt gtattgattg atttttgggc
    58981 aacttggtgt ggtccatgtc gtatgcaagc accgattttg gatcagttgg aacaagaata
    59041 tgatgaagaa gaattcagaa ttgctaaaat ggatgtggat gaaaatccag aaactcctca
    59101 acaattcggt atcatgagca ttccaacatt aatgttgaaa aaagatggtc aagtagtaga
    59161 aaaagctgtt ggtgttcatt caaaagaaca actacgtcaa atgatcgatc aatatttata
    59221 aaaacttaca gcaaaaataa gctgagggtg ggactgaatc cagttccgtc ctcggttttt
    59281 ttgcggttga gttaaggtta ttcaaattaa tattttttga gtataattac gttgtcaggc
    59341 tggattgttt ttttgacaga catgctataa taactttaat tgaatatgaa ggggagtacc
    59401 agatgaacga acgaatcaaa aacaaattag ctttacttcc tgatcagccc ggctgttact
    59461 tgatgaaaga taaaaatgga acgatcattt atgtcggcaa agccaaaata ttaaaaaatc
    59521 gtgtccgctc atattttact ggtagccata atacgaaaac ggaacggctt gttagtgaaa
    59581 tcgaagactt tgaatacatc gttacagaat cgaatatcga agcattgctc ttagagatca
    59641 atctgataaa gaaaaatgat cctaaataca acattatgtt aaaggatgat aaaacctatc
    59701 ctttccttaa gataacgaat gaaaaatatc cccgtttggt gattactcgt aaggtactaa
    59761 aagacaaagc actgtatttt ggaccatatc ccgatgtcgg tgcggcgaat gagacaaaga
    59821 agatcctcga tcgattattt cctctgagaa aatgcaaacc tagtcagacg aaggagcctt
    59881 gtctttacta tcatttggga caatgtctgt gtccttatta tttcgacgta gatccgaaag
    59941 tctatacgaa aatcgttgat gaagtgaaaa actttttaaa cggaggacac gaaaaaatcg
    60001 agtcagagat ccatcagaaa atggaaaaag ctgctgaaaa catggagttt gaaaaagctg
    60061 cagaataccg agaccagatc cgtgccattg agacaatcat gactcgccaa aaaatgacaa
    60121 atactgattt actggatcga gatgtatttg gttatgcgat tgataaagga tggatgtgtg
    60181 tccaagtgtt tttcgtaaga caaggaaagc taattgaacg agatgtttca atgtttcctt
    60241 tctataacga agcagaagaa gatttcttga cttacctcgg tcagttttat caggaaaatg
    60301 agcatttcat tcctaaagaa gtcttgattc ctgatacgat cgacaagccc agtgtagaag
    60361 ctttgttagc tacgaaagtg ctgcaaccaa aacgaggaga aaagaaaaaa ttagttgaat
    60421 tggcgagtaa gaatgcctca gttgctttga atgaacggtt tgatctgatt gccagaaaac
    60481 aggaacggac gatcggagca gttgaacgtt taggaaacgc gatgaatatc ccgaccccaa
    60541 tacgtatcga gtcttttgat aactctaata tcatggggac gaatcctgtg gctgcgatgg
    60601 tcgtattcat tgatggaaaa ccggcaagaa aagaatatcg gaaatataaa ataaaaacag
    60661 tcaacggacc ggatgattat gcatcaatga gagaagtcat ctatcgcaga tattcgcgag
    60721 tgattcgcga agggttgcct ttacctgatt tgatcttgat cgatggagga aaaggacaag
    60781 tagatgtggc aaaagatgtc ttagaaaatc aattaggaat cgatattcct attgctggca
    60841 tggcaaaaaa cgataaacat aaaacaaatg agttgctatt cggtacagat ttggctgtag
    60901 taccgcttga gcgaaattca ccagagtttt tcttactcca gcgaatccaa gatgaagtcc
    60961 atcgattcgc aatcactttc catcggcagc tacgcagtaa aaacagtttt gcttcccgat
    61021 tagatgaaat tgaagggtta ggaccaaaac gaaaaaaaat gctgcttaaa gagttcaaat
    61081 cgttgaaaaa tatcacagca gccacgacag aagaattaca agaaatcgga ctgccgaaaa
    61141 atgtcgcaca aaacgtattt gataaattac atcaggaatg aggaaagggc actttacaaa
    61201 gaaagtaaag tgtcctatca ttttatgtac aacaaaaaga gcgtttacgt tttgttggta
    61261 aataataaat cgcttacgtc tggtgtctaa ggatatatgt gatttcttga agaaggagtg
    61321 aagaaatgtt agaagtcaag gatcttgtta aaacttttgg gaactacaca gctgtcgatc
    61381 atgtctcttt ccaaatcccc gatggaaaaa tcatggggct aattggccaa aacggggctg
    61441 ggaagacaac gacttttcgt ttgatcttgg attttttgac acaagaccaa ggagaagtgt
    61501 tatggaatgg ccatcatctt ggggagaaag attatgatgt catcggttat cttccggagg
    61561 aacggggact ttatccgaaa gtaacgattc aagaccaact gctttatttt gcagaactta
    61621 gagggaaatc aagaaaagag attgaaccaa aaatcgactt ttggatggaa aaatttcagg
    61681 taaaagggaa aaagacggat aaagtaaaat ctttgtctaa aggaaatcag caaaaagtcc
    61741 agctgatcgc cacgttaatc catgaaccta aattgatcat tttggatgag ccattcagcg
    61801 ggttagatcc ggtaaatgct gaattgctaa aagatggaat attggaattg aaaaaacatg
    61861 gttcatgtgt cattttttct agccacaata tggataatgt agaaaaaatc tgcgatcatt
    61921 tgatcatgtt gcgaaacgga aaaatggttt tgaatggaaa agtacatgag attcgtgaat
    61981 catttggccg tacgaagtta ttcttggaat ctggtttaag ccaacaggaa gtagaagaaa
    62041 tcgaaggcgt gaaaaaagtg atccttcatg aagacaatac gttagagatt accttagaag
    62101 atcctgaagc tgggaaagaa atctttactc gtgcgactca gttcggctac attcctatgt
    62161 ttaaccagca accgccaact ttggaagaga ttttcaaatt gaaagcaggt gaaatcgatg
    62221 cgtaagtttt ggattattac caaagatgtc tatttaaaaa atgttaagtc gatttctttc
    62281 ttgatcatga tattagtccc ttttatcatg ctgggtatca tttatgtagc aggaaacttt
    62341 gctcaacaaa atagtgatgt caataaaatc ggcgtattgg ctgataatga gcaaatcagt
    62401 cagcaaatga gccaagtcaa aacagatgat tttgagttca aagcagttga ttctgaagaa
    62461 aaagcacaaa aagagctttc ggaagaaaaa atcgatgcgt atttagtagt ctcaactgag
    62521 aatgataaga taaatgggat gctttatagc gaaaattcat taggacaaag tacacaacta
    62581 ctgatacaac aacaactgac tggcttgcaa tcgatgcttc gagcgagtca attaggcatt
    62641 tcaccagaag aagtagctag cttgagccaa caagcaagtt tgactcgaca aaaagtcaat
    62701 tttgattcaa aaggaaaaat gacagtcgga gaagataact cgacagtcca atacgtcgta
    62761 agttatgtag caacgattgt cttgttcatt attattttga cgtatgcgca gatcattgca
    62821 caagagatcg cttctgaaaa aggcacgcgg atcatggaag tgatcctgtc cagtacgact
    62881 gcacaaaagc atttttacgg aaaattaaca ggtgttttac ttgttgcatt aacgcaaatg
    62941 gcattatacg gtattatttt tggtatagga tacagtcaat tcaaagatat ggaaatggtc
    63001 aaaaatatat tagacggtat ctcattggat aacttgattg gaccattctt gtggtattct
    63061 cttctattca tgatctttgg cattttgatt ttttctgttt tagcagcttt atgtggctct
    63121 ttggtcaaca aagcagaaga tacagcaaaa gcaattttgc cagtgactta tctatctcta
    63181 ggcggataca tgcttggatt gatactagga gcttcagatc caaacaatat cgttattcgg
    63241 atcacttcgt atattccatt cttatcttca tatattatgc cggttcgctt agcaaatgag
    63301 acagtcggta tgggtggagc attgatttcc ttgttggtac ttgtagccgt aacattctta
    63361 ttgatgatct tgtctgcaaa catgtacaaa tcgaatgtac tcgtttatag cgaaggcgga
    63421 ttatggagtt cattgaaaca atcgatttca attatgagga atgaacgaaa aaaagcataa
    63481 aacaatccta aaatacagaa ggaagctgga catctattgt tcccagcttc tttttgtata
    63541 gacctatttt atttatttta ctatattgga tatatattca ttgaaaatag tgtataacaa
    63601 ctttataata ttgagtatac caatttttgg aggcgtttta atggaccgtt atttagattt
    63661 actttcagaa aaattcccct caacggagga tgtcatcacg gaaatcatca atctcgaagc
    63721 aattttgcag cttccaaaag gaacagagtt atttttgagt gatatacatg gcgaatttcc
    63781 tgcttttgat catattctgc gtatcggttc aggaaatctt aaagaaaaga tcaaagacct
    63841 tttttctgaa caaatgacgg aaacggatat cagccaattc actattttta cggcttatcc
    63901 agaatatgca ttaacgactg attggtacaa agaacaagat aaatcgcagc tgatccatca
    63961 tttgatcgat cttttacggt ttacgacagt caaatatacc cggtcaaaag ttcgaaaagg
    64021 attgccgaaa gaatatagct atatcattga ggaactcttg tatatcgatg accgtatcaa
    64081 tggaaaaaaa gactatgtaa aaaaaatcat tgaacaactt gttttgatga aggaagaaga
    64141 aaaattttta acgaaacttg cacagacgat ccaaaaatct gtcatcgatc atttgcatat
    64201 cgttggagat atttttgacc gaggaactca agcagccaaa gtgatggatc gaatcatgga
    64261 tttttcttct gtagatatcc aatggggaaa tcatgatatt ttgtggattg gtgcgtattg
    64321 cggctctgag gcatgtttac tgacactttt acggattgca gcacgctata attatttatt
    64381 tgaattagag aaagaatatg ggttgaattt acgtccattg ttttcttttg ctcatcaaac
    64441 ttatcagaag aatccagtat ttgcgcctaa aaacagtaaa aatctatccg aaagagagca
    64501 agaagaatta gaaaaaatcc atcaggcact ttctatcctt caattcaaat cagaacatca
    64561 gttattggat cgtcgacctg aatttaaaat ggacgatcgt aaattgctgg aaaaaatcga
    64621 ctatgaagca tcaacgattg atttagaagg tcagctctat gagttgaaag gaacttgttt
    64681 tcaaacgatc cagccagatg atccaaaaaa attcttggaa gaggaacaaa aagtgattga
    64741 tagtttgatg tattcattcc agcactcttt gagaatgcaa aaacatatga cgtttttgat
    64801 cgaaaaaggg ggaatgtatc tcacgaacaa tcagcatgtg ctgtttcatg gctgtatacc
    64861 tgtagacgag aagggacagc tcttagcatt tgaattagac caatcttatc gcggaaaaga
    64921 actgctgggc ttttttgaaa aacagataac tgaaagcgca aaagatctga ctgcaaaaga
    64981 agatttagca accgatttga tttggtatgc gtggagtggg ccattttcgc ctttattcgg
    65041 caagagtaaa atggcgactt ttgaacgtta ttttctcaca gagcctcata cgcacgtcga
    65101 gaaaagcaat ccttattatc acttgcgaga tgaagagtgg ttcagtgaaa aaattttagc
    65161 agaattcgac acaaaagaag aagggtcagc aatcattaat gggcacacgc cagtaaaagt
    65221 aaaaaaaggg gagtcaccga tcaaagcaaa tggaaaagta tttgtcattg acggaggttt
    65281 atccaaagct tatcaaaaaa cgacaggaat tgccggttat tcactattat gcaattctta
    65341 tggtttccaa atcgtgacac attatccgtt tttgcctatt gaacaacaat ttgcaaaaaa
    65401 atccgaccaa acaaatgtga aaaaagtaat cgaacagcaa ctaccacgca aactcaatcg
    65461 tgatacaaca aaaggtatgg aactgcagca gcagattacc cagctcaaaa ggctgttgga
    65521 ctatcgaaag gacgattgag aagaattcca gtgaacattg ttccatagac tggagactga
    65581 gacaaaagtc gtgtcgcagt ctctttttcc ggataaacgg tgttcttctg ccaactcctc
    65641 ggtcacaagt cacactattc aacaaacatg aaaagctgtt ttttgaaatt gctccttgtg
    65701 actcagagtt gaacggcagg ctcacgacct cttggtataa acggtgttca aaagccagtt
    65761 tctcggtatt aagccaaatt tatgcaaaaa tgtgaaaagc cattttcaca aaatttttct
    65821 taatactcga aactaaacag ctttttcaca accccctcag aaagtctatt aaaattcatt
    65881 cacaaagaaa tcgaataagc gctgttcaga tggatgtaca cggtgggtaa gttccggatg
    65941 ccattgaaca ccgaggattt tatgcatatc atctttgctt tgaaccgctt caatgagtcc
    66001 atcgttagaa aaagcgatgg cttttaataa aggtgaaaga tctttgactg cctgatgatg
    66061 gtaagaattc acaaaatatg gatcggggag aaggttgctt aacaaactgt ctgaaacaat
    66121 cttgacttcg tgagtcgtaa attgcggggc agtgggctgt tgttcatgtt ttactgacca
    66181 ctttggatat aatgaaagat cttgataaag tgtaccttcc aaaacgacat tcaatagttg
    66241 gagtccccgg cagactgcaa aaattggttt tctttgtttc aatgcttcca agatcagtgc
    66301 ctgttcaaat tggtctcgtt gaatatttgt ttccgttagc tttggatgag gatcttccat
    66361 gtaaagttgt ggactgacat cttgaccacc tgcaagaata agtttgtcga tttgtccaat
    66421 cagttgagga gctgaatctg gagacatgac tggcagaata agaggcaatc cttgagcatc
    66481 taaaactgca tccacgaatc cttgcggtgt atagctcact tgatttcctt ggaaagtatc
    66541 tgttgctcga atcagttgat ttccggcaat gccgatgatt ggtttcattt gtattccccc
    66601 taaagtagac ttattgtaac aaggatttaa aaaaaattaa actatgtaag acttgcccct
    66661 atacttatct gttcttgctg tgttactatc tgtaaagaga aatttcgtgt gaaattcatg
    66721 acgatagttg aaaatattgc ttaatttgtt ataataaaaa gtaagcagaa ataaaaaggt
    66781 tgggcgtaag cttcaaggat ctagttcttc aaggggtgag aaggacattt tattgaaggg
    66841 gcctgcctat actaagttat ctttagaggt acatactttc aatgaaaaaa gaaagcatgt
    66901 acctcttttt taaatcgaaa ggaagtgaag caagtgttag aagctttgga acaaatccga
    66961 aaagcagaag aagaaaatga aaagcgtgct caaacactgc ggcagcagct gaagatctat
    67021 gcaacagaaa aagagcagga attggaaacg atccaaacaa actatcgaca acaactaaaa
    67081 cagttggtgg aagaaaaaga acaatttgaa atacaagaat tagaaaaaga aaaaatgaaa
    67141 ttgaaagcag aagcagacaa ggtgcaagca actttgaaag atcaatatca aaagcatcag
    67201 agtcaagcga tcggtgcgat cattgaaagg gtgaaagaaa cttatggccg tcactaagat
    67261 ggaaaaagtg accctcattt cagataaaag aaatcaggag aggattttac aagcagtaca
    67321 aggaatccaa aacgttgaaa tccgggatct gtatcaaaat agaacaaaca accagtgggt
    67381 ggagaagtat tttccagata ccacgattat tgataaagaa gcaaaattaa gcgctttagg
    67441 taatcggttg aaagacatcc aagaagctat ccaattcata caacaccacg gcgatagccg
    67501 tcaaaagaaa ctccatttga aacgtcaaga actttcctta caagatttgg aagccaatta
    67561 ttccgaagaa aatttcataa ataaattgaa agaagtcctt gatttaaaag aaaagtggga
    67621 acaactaact gaagaacgtg atcgtttaga agaagaggaa gaatggcttc ttcattggca
    67681 acagctggat attgctccaa gtatgtatgc aagtaagacg accatttttg agatggggac
    67741 tgtgagtgca gcaaattttg aaagtttcaa ggaagaactg agtaagcttg atgacgttta
    67801 tatggaagaa atagattata cgccaaaaca agtttatctt tcgtatgttg ctttaaaaaa
    67861 atcagttgct gttatagaag aaattgctgg gaaatacggg ttcaataaag aaacgtatcc
    67921 ttatgaacaa aatcctaaag aaaaactgca agagaccaag cagcaattat ccattgttca
    67981 cgagcagcaa aagaagataa cgacagcgtt aggtcagtgc agtggctata tccaagaatt
    68041 tgaatgggta gaagaagtca cacttgccgt tgcagaacga gaaaaaataa aagaacggtt
    68101 tatccatgcg acttatctga tcgttttgca aggttgggta gatgcagaag aaaaacagaa
    68161 tttgctgcat gtgttaaacg aaaccgtatc agaagaagat atatacgtca gtttcgaaac
    68221 accaaactca gaagagattc agcaggaagt ccctactaaa ttgaaaaacc atccgcttgt
    68281 cgaacctttt gaattgctga ctgaaatgta cagtctgcca aaatatgaag aagtagatcc
    68341 aacaccttgg atgacaccat tttatcttgt cttcttcggg atgatggtcg cagatgttgg
    68401 ttatggtttg ctgatgctca ttgggacaat actagctcaa aaactacttg ttctaccacg
    68461 cgggatgaaa cgtttcgtaa aattctttga gattctctcg ataccatcga tcatctgggg
    68521 attgatctac agttcatttt tcggacagtc attaccaaaa gaactgtttg gcatccgctt
    68581 gcctttccca atcctatcta cgacggatga cgtcaatacg attttgattt tatccgtgat
    68641 tttcggtctg atacagattt tggttggatt atttgtggca gcaaaggaaa atatcaggag
    68701 aaaagattac ttgagtgctg tcagtgatgg atttgcctgg caagggatcc taattgggat
    68761 cgttattgcg ttggttggtg ccatgttgat aaaaaataca gcatttgttt accttggcgc
    68821 tgggctatcg atcattgctg ccttatgtat cttgatcgtt ccgattatcc aaacgccgtc
    68881 taaagtcaaa ggtgctgcca aaggtgcgta taatctttac ggactgaccg gctatatcgg
    68941 tgatttagtc agttatacac gtttgatggc attgggtatt tcaggcggaa gtattggagc
    69001 ggcattcaat atgctagttg ctttcatgcc gccagctgct cgattcagtg tagggatcct
    69061 tttgatcatc gctttacacg cactgaatat gtttttgaca ctgctaagtg cctatgtcca
    69121 tggcgcacga ttgcagtatg tcgaattttt tgggaagttt tatacaggag gcggacgtgc
    69181 ctttgatccg ctgaaaacgg cggaaaaata cgtcaacatc aatcacaaga aaaaaaacaa
    69241 taaataattg gaggattttt atataatgat ggattactta attagtcaaa atggtggaat
    69301 ggtatttgcg gtattagcga tggcaacagc gacgattttt tcagggatcg gttcagctaa
    69361 aggtgttgga atgacaggtg aggcagcagc agcattgaca acaagtcaac ccgaaaaatt
    69421 cgggcaggct ctgattctgc aattgcttcc aggtacgcaa ggtttgtatg gattcgttat
    69481 tgcctttttg atttttatca acttaggaaa tgacatgtca gttgtacaag gactgaactt
    69541 tctaggtgct tctctgccga ttgcttttac aggcttgttt tcaggtattg cccaaggaaa
    69601 agtcgcagcg gcaggtattc aaattttagc gaaaaaacct gaacatgcta caaaaggaat
    69661 catttttgct gcgatggttg aaacatacgc gattttaggt ttcgttattt ccttcctatt
    69721 agtgttgaat gcctaagcat aaaggaggaa aagcagatga acgccattga aaaaatcatc
    69781 tctcagatga acgaagcagc agagcaggaa agagcggcgt tagaacaaga agagcgaatg
    69841 aagatcgatc aaaactttga acaaaaacgt acgcaagttg aaacagaaca tcaaaaacaa
    69901 aaagaaaaac aaatcgaatt actcgaaaaa aaataccgtc agctaaggaa tcgccagcaa
    69961 gtagaagtac gacaagaaaa tttgaatgcg aagcaggaat ttttaagacg attgtttgca
    70021 gatgcggtaa ctgaaatgga aaattgggat gaatctgaac aaatccagtt tatcaaaaat
    70081 gcattgtatt cattaccttt gacaggaaaa gtagcattca ttgctggaga aaaatcagca
    70141 gcctatcttt ctcagacgtt gttggatgaa tggaacaatg aacttccctt tatgatggtt
    70201 ttaagtgatg aaactgttgc tgatcaagcg ggttttctga taaacgatca aggagttcag
    70261 tataattttc ttttcagcag ccttgtacaa gatatccaag gaacgatgag ttttgagatt
    70321 gccaatcaat tattcgaata aggagggatc agtgtatgga ataccacgaa ctaaatccct
    70381 tgattcgcgg aagagagctt gaacttttgt ccaatgagac atttgaacgg atgattcaaa
    70441 caaattctgt cgaagcactt ggtgaaatat tgaaatccac gatttacagt ccatatattt
    70501 atgacggata tgaatatgac ttcgaacaga atcttttaaa ggagcagagc cgtctatttc
    70561 gctggttaaa ggaatcagca ccggagcctg aaatcgtttg gatctatacg atgcgttata
    70621 ctttccataa tctgaaggtt ttgacaaaag ctgagatgac aaatcaaaat ctggaccatt
    70681 tgtatatcga cgatggattt tattcattag aaaccttgaa ggatgccatt catacgcaag
    70741 tttcaaatga acttcctgaa agcattatgg acagtatacg agaagtacgt gattattttg
    70801 aagagtctac cattcttcag ggaattgacg tgatttatga tcgacagttt ttgacagagc
    70861 agcgacggct tgccgataag ctaggatatc aagaattgct gacagaagtc attgctttta
    70921 ttgacttgac caatatcaca acgatggctc gaggaatatt gcagaaaaga acatatgggt
    70981 tcatgacgac ggtactttcc agctcgggaa gtatcgaaaa agaagtattt ttgaactttg
    71041 tagataaaga tatggaagat tacacgaatt ttctattaga gacagattat gctgattttc
    71101 tgcgccctgt catccgtgag ggaaatattg atctcgtaaa gcttgaacag ttgaaagatg
    71161 attatctaag ttcattgtat caagaagcac aaacccaggc tttcggacca ctgccactac
    71221 tagccttttt gaacgcaaaa gaggtagaaa gcaaaaacct tcgtttactg gttatcggca
    71281 aaagaagcca tttcgaatca gaaacaatca gaaagcgggt gagacaagtc tatgacgcat
    71341 aagatcggtg tagttggcga caaagattct gttttgccat tcaaattgtt tggctttgat
    71401 gttcgttatg gtacaaccaa gcaaaccgtt cgtcaggcaa ttgaagaaat ggcaaagaat
    71461 gagtatggcg tgatttatgt cacagagcaa tgtgcagcat tgagcccaga aacgatcgaa
    71521 cgttacaagg aacaaatgat acctgctatc gtattgattc ccaatcatca aggatcatta
    71581 gggatagggc tggaagaaat tcaaaaaaac gtagaaaaag cagtaggtca aaatatctta
    71641 tagtatgaaa aggagataga aattttgcaa attggaaaaa tcataaaagt ctccggacct
    71701 cttgtaatgg ctgagaacat gtctgatgcc agtatccaag acatgtgtct agtgggagat
    71761 ctaggagtta tcggagaaat tatcgagatg cgtggcgatg tggcgtctat tcaagtatat
    71821 gaagagactt ctggaattgg tccaggcgaa ccggttcgct ctactggtga agctttatct
    71881 gttgaattag gaccagggat catttcacaa atgtttgacg gaatccaacg gccattagat
    71941 acctttatgg aaatcacaca aagtaatttc ttagggcgcg gagttcaatt gcccgcattg
    72001 gaccatgaga aaaaatggtg gttcgaacca acagtagaag ccggagaaac ggtgagtgct
    72061 ggagatgtta tcgggatcgt agaagaaaca aaagttataa aacataaaat catggtgcca
    72121 aatgggataa aaggaacgat caaaacaatc gaaaaaggtt cattcactat tgatgaaaca
    72181 gtatgtgtca ttgaaaccga aaatggtgac aaaaatttga cgatgcttca aaaatggcca
    72241 gtaagacgta gtcggccaat caaagaaaaa ttaaacccgg atgcacccat gatcactgga
    72301 cagcgagtga ttgatacatt cttcccagtg acaaaaggag gagcagcagc tgtacctggt
    72361 ccttttggtg cagggaaaac agtcgttcag catcaaattg caaaatgggc cgatgtggac
    72421 atggttgtct atgtgggatg tggcgagcgt ggaaatgaga tgacggatgt tttaaatgaa
    72481 ttccctgaat tgattgaccc taatacagga gaatcgttga tggaacgtac ggtattgatt
    72541 gctaatacat caaacatgcc agtagcagct cgagaagctt ctatctatac gggaatcaca
    72601 attgcggaat atttccgtga catgggttat gacgttgcta tcatggcaga ctccacttca
    72661 cgatgggcag aagcacttcg tgagatgagc ggacgtttgg aagaaatgcc tggtgatgaa
    72721 ggttatccag cttatcttgg ttcacggctt gcggaatact atgaacgatc tggaagagtc
    72781 attgcattag gatcagaagg tcgcgaagga agtataaccg caatcagtgc tgtatccccg
    72841 tctggagggg atatttcgga accagtcaca caaaatacat tgcgggtcgt aaaagtattc
    72901 tggggtcttg attccagttt agcccaaaaa agacattttc cttcgatcga ttggatacaa
    72961 agctattctc tttattcaac agaagtaggg aagtatatgg atcatatcct tcaagctgac
    73021 tgggcatcca tggtcaccga gggcatgcgt attttgcagg aagaacagca gctgaatgaa
    73081 atcgtgcgtt tggtagggat tgattccctt tcagataatg accgtctgac attagaagtg
    73141 gcaaaatcca ttcgtgaaga ttatttgcag caaaatgctt ttgatgatgt cgatacattc
    73201 acttcaagag agaaacaatt caaaatgttg aagatgatct tgacctttgg tgaagaagga
    73261 cgccgtgcgt tgtcgttagg tgcttattta agtgagatca tggacggtac cgtatcgatt
    73321 cgtgaaagga tcggacgaag caaatatatc ccggaaacag aattagaaaa actagatcaa
    73381 attattggtg aaatcaagca aacgatgcaa acgatcgttt cagaaggagg catgagcaat
    73441 gattaaagaa tatcgtacga tcggtgaagt cgtcggtcca ttgatggcgg ttgaaaaagt
    73501 tgctggtgtc aaatatgaag aattaatcga agtccgtatg caaaatggcg agattcgtcg
    73561 tggacaagta ttggaagtcc aagaagataa agcaatggtc caaatattcg aaggaacaag
    73621 tggtatcaat ttacgtgact cttctgtacg atttttaggc catcctttag aactaggtgt
    73681 atcggaagac atgatcggtc gagtattcga tggtttggga cgaccgaaag ataacggacc
    73741 agagatcctg cctgaaaagc atttggatat taacggagaa gtaatcaatc cagtagctcg
    73801 ggattatcca gatgagttta tccaaacagg tatctctgca atcgatcatt tgaatacatt
    73861 agttcgtggg caaaaattac cagtattttc tggctctggt cttcctcata aagaattagc
    73921 tgctcagatc gcgcgacaag caacggtact cgattcatca gatgatttcg ccgtagtctt
    73981 tgctgctatt ggaatcactt ttgaagaagc tgaatttttc atggaagatt ttcgtcaaac
    74041 gggcgcaatc gaccgttctg tcatgtttat gaatttagca aacgaccctg caatcgaacg
    74101 tatcgctact cctcgtatgg ctttgactgc tgcagaatat cttgcttatg aaaagggaat
    74161 gcatgttttg gttatcatga cagacatgac caactatgca gaggcattgc gagagatttc
    74221 tgcagcacgg cgagaagttc caggaagaag aggatatcct gggtatcttt acacgaactt
    74281 agctacttta ttcgaacgag caggaagaat ccgcggacta aaaggatcgg ttactcaaat
    74341 tccgattcta acaatgccag aagacgataa aactcatcca atccctgact tgactggtta
    74401 tattacagaa ggacagatca tcttgactag agagctttac aagagtggga ttcagccacc
    74461 aattgatgta ctcccgtctc tttcgcggtt aaaagataag ggaactggac ccggaaagac
    74521 aagagaagac catgcagcta cgatgaatca gctttttgca gcctatgcac aaggaaaaca
    74581 ggcaaaagaa ttagccgtag ttttaggtga atctgcttta tctgatgtag acaagatcta
    74641 tgcgaagttt gctgagcggt ttgaaaaaga atatgtcaat caaggattct acacgaaccg
    74701 ttcgattact gaaacacttg atctagggtg ggaactgcta tcgatgttgc caagaaccga
    74761 attaaaacga atcaaagacg acatgctgga caaatatctg ccagaaggga agtgagttct
    74821 gatggcacga ttgaatgtga atccgacccg catggaattg actcgattga aaaaacagtt
    74881 gacaactgcc acaagagggc ataaattatt aaaagataag caagatgaac tgatgcgtca
    74941 attcatcctg ttgattcgaa agaacaacca gctgcgtcaa gaaatggaag agtctatgac
    75001 agaagcaatg tctgattttg tattggcaaa tgcttcgatc acggaacctt tcatcgaaga
    75061 attatttgtt ttgccggcgg aaaacgttga tttgtctatc gtagacaaaa atatcatgag
    75121 tgtaaaagta cctgtgatga attttgaata tgatgaacag ctgacagaca cacctttgga
    75181 atacgggtat ttgaattcca gtgccgaact ggatcggtca atcgatcggt ttactaccct
    75241 gcttccaaaa cttttggaac tgacagaaat cgaaaaaact tgtcaactga tggcgagtga
    75301 aatcgaaaag acacgtcggc gagtcaatgc attagaatat atgacgatcc ctcaattaga
    75361 agaaacgatc tattatattc gtatgaagct ggaagaaaac gagcgcgcag aagtaacaag
    75421 gttgatcaaa gtaaaaaata tgggtaccac tgactaagtg gtatcttttt ttaaaagagg
    75481 aaaacgatga ttaaacaaag caaacaaata aagaaacgtt tgccggctgt tcagcttctc
    75541 gcattaggat tttttctcct gattttagtt ggcggcggcc tacttaccct accatttttt
    75601 agtaatagtg ggcatgggac aaattttatc gatgcgcttt tcactgcaac ttctgctgtc
    75661 tgtgtaacgg gattgacaac attgaataca gcagagcatt ggaacagtgc tggtcaattt
    75721 ttgatcatgc ttttgattga gatcggcggt cttggtttta tgatggttcc gattctatgc
    75781 tttgcattga taaagaagaa agtcagtctc agcacacgta ttatattaaa agaagcgctg
    75841 aatctagaag aagtatcagg tgtgatgaag ctcatgcttt acatcctaaa attggccttt
    75901 gtgatccaat tgattggtac ggttgcttta tcttttgtat ttgtgcctga atttggctgg
    75961 ttgaaaggta tctggtacag tttgttccat gcaatctcta gtttttgtaa tgcagggttt
    76021 gatttgttag gagacagttt agccaatcac cagcaaaatg tttatttgat catggtggta
    76081 tctgctttga tcatttctgg tgggttaggc ttcatcgtat ggcgtgattt actggaatat
    76141 catcagaaaa agaagatgac gattcattca aaaatcgcat taaccgttac aggtaccctt
    76201 ttattaggcg gattcgttgt gttctttttc acagagcgca atggggcaac gctagtggaa
    76261 gggaatatgt ttcaacgatt ggcaaacacc ttttttatga gtgtgacacc tagaacggct
    76321 ggatattatt cagttgatta cctccatatg agccatgcag gtctgatttt aacgatgttt
    76381 ttgatgtaca tcggcggaac atctgggtcg acggccggcg gattgaaaac aactacgtta
    76441 ggtgtgttgc tgatccagat gcgttcgatg ttgaaaggac gtacgagagc ggaagcattt
    76501 ggccgtacca tccgacaagg cgcagtgttg cgggcactta ctttattttt tgttacgttg
    76561 acgttgtgtg tagtcgccat catgatttta tcggtgactg aaacgatacc taaaacttct
    76621 ggcatcgaat atattgcttt tgaggtcttc tctgcgtttg gtacagtagg tcttacgatg
    76681 ggattgacgc cagacttgac tgcaataggg aaattgatca ttatagcgct tatgtacatt
    76741 ggacgagttg gtgtattgac tgtggtcttc tctctgatga caaaagcaca aagaacacaa
    76801 tcaaaataca aatatccaga agaaagtgtc atgattggat aatttcatct tctgacagaa
    76861 acctagtgat ttagtaaaat aagaaaataa aataattttt cttgcttctt ggatacttta
    76921 agtgcaaaat gttcgtttat tttttgaggc actacccgtt gttgaacctc gggtagtgcc
    76981 tcttttttat tgaaaggaat caataagatt tgattccttt atttatcaat aggttataat
    77041 tcatattttt ttattttttc ttttacgata cttagtccag aagctaaaat ttcaaggtta
    77101 ttagaggata gggaaattcg aacgaatgca tctggttgcg tacgtgtagt aaagcgtctg
    77161 gaatgataaa gtcggatacc gttagcaaga aagtcattct caattatctt agggtcaatc
    77221 tcaggatcaa ctggaagaat tcgatagtaa gggacacgat tcgttggttt ttctactttg
    77281 aaaagagaat caaaaagctg attggctctt tttgtaagac ttaatttagt ttctaagatc
    77341 ctatttgctt catttgaatg gaggatttga gtgatgactt ccacatctaa tccagaagtt
    77401 ttcacattta tattaaaaat tgcttgttct atcttgcttt ggacatgtac tggaactaca
    77461 agataagcaa ctcgcaatcc agaacaaata aattttgtca ttccagctaa gtagattgtt
    77521 tggttaggta ataaattttg gaaaggagga atgatcgtat gttgatagta agttgttaaa
    77581 aatgaatgga tatcatcttc aataacccat agaccttctt tttcaatcac ttcggctaat
    77641 tgctctcgtc ttttgtgaga gatttgaaac cctataggat tattacaaga aggcataaga
    77701 aagacaccat gaatcttctt ttttctacat tcctgaatca atatatcagg tcgcattcct
    77761 tgctcgtcaa aatcaattgg aacgatctct aaatgatata actgagccaa ttcaatgaaa
    77821 ttagcgtatg tatatcggtc tgttgctatt ctatcacctg gagagaaaag tgcagaaagt
    77881 gtgatagcca atccattttg aacaccggaa acaatagata gagattctaa ggacggaatg
    77941 actccttgag tttttaacca atttgctgca gtagtcaatt gaaaatttgt gcctttggga
    78001 tcttggtaat taagcaaacc aacaagattt gggttattac tagttgattg aataaacggg
    78061 acaacgaatt tattacattc ttcaaaagaa ctaaccagac caaaatcaat gatatgttcg
    78121 gttacttcat tggtagagat ggtgatggac tcaaagacat tgggagaaat aaatgtgcca
    78181 cttccaatat tcgtatacag caaacctttc tcaattccat atttataagc cttgccaacg
    78241 gtagtaaaat ttaaatctaa ataatcagct agctctcttt gggagggtaa ctgagtgttt
    78301 ttctgtaatt tattctttaa aatatcttgt tctaattgtt gaatcaacga tcgataataa
    78361 ggacgcttca atttttgttt gtctggtcgc caagttaacg ggtaattgtc ataagaatta
    78421 ataggcattt tctccactcc ttaaaattgt ataccataca attttaccat tgattgtatt
    78481 gattttagaa gttaatcttt tgtgaggagg gaattgtcta tgaaaattat taattttgag
    78541 gaagtagtag cttcttttag ttttgaagaa gcgattcaag taatgaaaaa atgttttttt
    78601 gattatgaaa gtggtaaaat cagccaaaat cctcgattgg tggaaatttt acctgacgga
    78661 aaaggcaaaa atatgtttgc gatgatgcct gcttatttgg gggagaacag atattttggc
    78721 acaaaagtca ttaccgcttt tccggataat catcagtatc atttaccttc tcatttagga
    78781 gagattttct tgtttgatgc tcaaaacgga ctacccaaag cattgataaa cgcaaatgca
    78841 gtcacctgga ttcgaacagc tgctgtatct gcgctggcaa cagattactt agcaaatccg
    78901 catgcagaaa cacttgcttt aattggagct ggtcaacaag cattgtcgca tttgactgcg
    78961 atttctacca ttcgtcccat cactacagtg tttgtttacg atattttaga agaaagacga
    79021 aatactttta tcgctaaagc taaaaaacag tatcctaaaa taacgtttat aaatgcaata
    79081 tcagtagaag atgcagtacg tccagcggaa atcatttgta cgttgacctc tagtaaagag
    79141 gcatttcttc aaaaagagtg ggtaagggaa gacgcacata tcaatgctgt gggcacattt
    79201 actcctgata caagagagat aagtacatcg ttgatggaaa cttctcaaat ctatgtagat
    79261 gattactcag ctgccttaac agaaagcggg gacctgctta tagccatggc agaaggagat
    79321 ttagaggaat cttgtattgt tggtacatta ggcgaattag tttctgagaa aaaaacattt
    79381 tataaaggag aatcgaggcc gacgattttc gacgcagttg gtctagctat tgaagatctt
    79441 tgttgtgcag aatatattta taacaaatta gagaaagggg ctttaaaatg aacttagatt
    79501 attacgtagt tgatgcattt gcagatgagg tgttcaaagg aaatccagca gcggtttatg
    79561 tgctagaaga atggctgcca gaaggtacga tgcaaaaaat tgccattgaa aacaatttat
    79621 ctgaaacagc atttacagtg aagaaaaacc aagaatttga gcttagatgg tttacgccag
    79681 atcgagaaat cgatctttgt ggtcacgcga cattagcaac agcatttgtt ttatttaact
    79741 attacaaaat acctgatgaa acgattaaat tttctactca aagcggtaat ctatttgtga
    79801 caagaattaa agattattat tacatggatt ttcctagtat tatgccgaaa aaagtgccga
    79861 tattgtctga atatgaagaa gcgattgggg ctaagattaa agaagcctac ttagcacgtg
    79921 atttattttt cgtattagaa gatgaaaaaa cggtggctaa attgcagcca gattttacag
    79981 ctatcaaaaa ttttgaatta ggaataggag tcatcgtgac agcagaaagt gtgcaaaaag
    80041 actttgtttc tagaaccttc tttccaaaat taacaatcaa tgaagatcca gtatgtggat
    80101 cagcacattc taatcttatt ccttattggg cagaaagaat gaataaaaca aaattgtcag
    80161 cttatcaaat gtcatcaagg ggcggggatc tagaatgtga attaaaagaa gatcgtgtga
    80221 taataggagg aaaagcagtt ttgttttcta aaggtacctc gtttatttga tttctttcaa
    80281 atgaattaaa aataaattgg tggagagtgg caaccttata gctacaatgg ttgttaaaaa
    80341 aagacgcaaa ctttttcaat ttaatgaaaa gtttgcgtct cattttaatt attggtgttt
    80401 gttttttatt caatcaagag taaaatgccc catactaact atcctcggat gacttcgatt
    80461 ttataaccat cagggtcaat gacaaagtag taagaaggcg cagtgccagg taatcctttt
    80521 aagtcagtaa tctcaagacc agcagcttta tgttgctcgt gtaatttttc tagatcatca
    80581 gctgctatag cgatatgacc atagccgtct cctagatcat acgcaccatg atcatagttg
    80641 taagtcaact ctaattcata gtcatcccca ggaagtgtca aataaacaag tgtaaatttg
    80701 ttttctggaa aatcacggcg gcggctttct tcaaaaccaa atgccttttg ataaaattcg
    80761 attgatgctt caagatcttt cactcgaaca catgtgtgag ccattttcat agattcatct
    80821 ctccttttcc ttttactcaa tcataacaaa aagaagtaag gaaatagttg atttgtgctt
    80881 gttcatgaga aatttctcat gtaaaatgga tagaaaataa aactgttaag gtggaaacta
    80941 ttcatggata aaccaatttt tggtgaaaaa aagcaatttg ctgattatca aacccgttat
    81001 gcagcatata ttgtcataga aagagatcag cagattgcag taatcgaggc tccaaatggt
    81061 gctttttttc ttcctggcgg ggaaattgaa ggagaagaga cgaaagaaga agcgattgtc
    81121 cgtgagctga tagaagaaat gggaattgtg gcagaaattt cttcttatct gggagaagct
    81181 gatgagtatt tttactcgaa ttatcgtgca acttattatt ataatccagg atatttcttt
    81241 gttgctgatt cttggaagcg tataggagaa ccaactgaaa agaccaataa aatttggtgg
    81301 gtgagccctc aagaagcgct tgtgaaattg aaacgtggta gccaccgatg ggcagtcgag
    81361 agatggatcg aaaaaaataa aaactgaaag aaagcgagta gatcagcttt ctctcagttt
    81421 ttttatttat tacagtacat attttttgat tgcttcagct acaccgtgct cgtcgtttga
    81481 tgaagtgatg acatttgctg cttctttgac aagagaaacg gcatttccca ttgctactcc
    81541 tagaccagca tattcaatca tggataagtc gttctcgtta tctccgatag ccatgatttc
    81601 atcttgatca ataccaaggt gctgtgcgag attcgcaact gccgcacctt tacttgcttc
    81661 tttatttagt acttcgaagt aatagggcgc acttttgacc gttgtgtatt tatcacggaa
    81721 agtttgcggt aaacgcgcaa ttgctgcatc taaaatttct ggttcgtcga tcatcatcat
    81781 tttgacgatg ttcatgtctg gtgtcatttc ttcaggtgtt cgatatttta gcggcatctt
    81841 gactaaactt gcttcgtgga tcgtataagc gctgatatct cgattaggcg tgtagatcgc
    81901 tttgtcatcg atcgaatgga gatgactgcc gacacggcgt gccatcactt cgatctctag
    81961 gaaatcttca tgtgtcagtc cgtgacgggc gatgatttta cctgatttcg tttgttgtac
    82021 gagtgccccg ttataagtaa taacgtaatc attatcttga aaaaggttca actcgtttaa
    82081 ctgttcctgg acacctggta agggacggcc agtgcataaa acgatcgaaa caccttttgc
    82141 aacagcagcg gcaatcgctt cttttacttc ttttgttact tctcttttct catttaataa
    82201 agtaccatcg atgtcgatag cgactagttt gatagacata atttcctcca atatatttta
    82261 atttatttca atcaatgcgc cattacggat atggctggca aattcttgat aagtttcgtc
    82321 aaataaatca taatgatcac gcaaggacgg atcaaccatt tcttttggaa agaaaaatcg
    82381 ctcatctcct tgttcttgtc ccgctaatgc agcaacaagc tgactaacct gtgataattc
    82441 tatcaaagtt ccgtcatttc gcaaaatctc gatttgtgtg cgatgtctgc cttgttctgg
    82501 gcgataaaaa tcataaggta gatcgtagct agaattcaca gcagtgtaat aaacaggatt
    82561 atatccgacc ttttctacta acaaagtgag ttcttggact aattttgaat cccggttgcc
    82621 agaaaaagta gcagatttca gtggtttacg attcaaaaaa cgtttagcta aatcatttaa
    82681 aataggatca gcagattcag accattgagt aaagtaagtg cccaagaccc catcatcaag
    82741 tttgaggtat tcttctaaag taaagcttcc gtcaagaaat ggcagaagta attgagaatg
    82801 gagttcaaaa ctgctggcat cttcttgata caactcgtgt gcgcgatgaa gcagatgctc
    82861 caaaattact tccataccac gggaaacagg atggaagtac acttgcacat acatttgata
    82921 tcggctaacg atataatctt ccactgcatg catgccactc atggaaaaag cgatcccgcc
    82981 ttcataagga cgaatcacac gtaatattcg ggtaagatca aatgttccat attctgttcc
    83041 agtgaaataa gcatcccgaa gcaaatagtc cattcgatct gcatcgatct gactagaaat
    83101 catttggaca acttgtgggt tggggtaagt tttttggatc acactagcta ccttttcagg
    83161 aaaaccttct tctactcggt taagaatctg atacacttct gtttctggag aagtgatgat
    83221 ctctacagtg atggcttcat gattcgtatg gaagatatgt tcaaatgtat gagagtaagg
    83281 accatgaccg acatcatgca acagtgccgc acataaagtc accagccgtt cctgatcatc
    83341 ccagcctccg ttgcctattt tttcttttga aaaatttcga gaaaagatat cgcagattcg
    83401 tcttgaaatc tcataaacgc ctaatgaatg agtaaaacgg ctatgttctg ctccgtgaaa
    83461 agtgaaagaa gaagtgccta attgtttaat gcgtcgtaga cgttggactt ctttcgaatt
    83521 gatcaaatct aagattactt gatgctggac atggatatag ttatggactg gatcacgaaa
    83581 aactttttcc ataggcagca tttgatattt ataaggggtt gtcataatgt agctccttta
    83641 tgttattacg ttgttccatt ctctggattt ggttgttcca ttgctccagc tggatttctt
    83701 tttttagcca gtcggtagaa tcctgtaaat cacttgcaga atacagcttt tcaaaagctt
    83761 ttgcaaatgc ttctttgact tcttttacaa aaaggggttg gtcaagcagt tcttcaagtg
    83821 ttgccattgt agcaggatcc actgcaggat agccatttgt accaaagtct tcttttaaag
    83881 cagattgata aaatcgcttc atgacttgcc cgcgtttttc ctgattaccg ttgacactta
    83941 agtacatcat aacagaaatc ccatttttga tccgacgctg agcgataccg gcaaattttt
    84001 tgccatggat gcttaaatca taagttccag gacaataaga atgggtgatt tcgaatgctt
    84061 gtatcggtgc ctttggaaaa gcgtatttag tcaataggag catttgctcg taagcgtcat
    84121 ctatggttat tttttttgtg tcactttggg ggaaaatcaa agaaatattc aaaattcctt
    84181 catctgatac gatccctaat ccacctgaat ttctgatcac tggagcgtaa cctgcatctt
    84241 tcagtgtttg gatcccgtca cttagaaaag gagttcgaac atccttcata cctaagatga
    84301 ctgtgcagtc atattgccag aaatgtaaaa agatttgctg gtgttcttta gaatattccg
    84361 ttaatatatc tgttaatgca aaaggggaaa agtcgttttt ttgataaatg tgctgatcta
    84421 gtcgaatcgc agggttcatt caaccggctc ctttgtataa attcatattt tctacaatat
    84481 tatactctaa aatcaaagag ttgttttgga aaaaaggttt tctgtaaaaa tggacaagtt
    84541 ggttgacaaa acaaaagaaa ctaggaacaa tgtagctatg agaagtaaag gagaatgaat
    84601 aatggaatta tcacaaggaa caccgatttc aatcaaattg cgtacaaaag taaaacagca
    84661 aggggaagtg caagattttt attttgattt gaaagggcaa atggtgacaa ttggcgatac
    84721 gctgtacata cgttataaag agattcagga ggagacgggc gatgagattc ctgtaacgat
    84781 caaattagtt ccagatggtc atgtacagct gatccgtgca ggagaaatgc ggatgcgttt
    84841 gaaatttggc tataaagaac ggttagaaac atcctatcga acaccatacg gtatgatcca
    84901 gattgctact tttacgaaag aactgcatgt tagtttgaaa gaccgtccca cagcagggaa
    84961 ggttcgaatc gattatgatc tgttcatggg accggaaaaa atcggcgaat attatttgac
    85021 cttggatttt acagcgtaaa tataaaagaa aagtttgatt ttttgtgtct gattttgtat
    85081 gataaggagt agactgtgaa aggacgtgtc ctgattggaa attagtgtat ttgaaggtgc
    85141 aaacaaaagc gaattatcaa tgatcgaagt agcacacgcg atcttagaac aacgtggcga
    85201 tgtcatggat ttttctgatt tagctaacca gatccaaaac tatcttggga aatcagacag
    85261 tgaaattcgt gattcactcg cacaatttta tactgacttg aatattgacg gcagctttat
    85321 ctcattaggg gataatcgtt ggggcttgcg ttcatggtat gctatcgatt cgatcgatga
    85381 agaagtaaac catggaatgg acgaagagga tgaagatact ccacgtcgcc gtaaacgcaa
    85441 gaaagtcaac gcctttatca atgatgatga agacgcgatc gattacaatg acgatgaccc
    85501 agaagataca gatctgacag aagaagatga cgatgatctg tttgatgacg atgatgatga
    85561 agatgaagaa atcgctgctt ataattctga cttgcaagaa atcggagcag atgacccgac
    85621 agatgatgaa gaagacttgc caggaaatat cgaagaagat ttaagtatca tagacgaaga
    85681 cgatgatgat gaagattatg aagaggaaga attttctgac tctgaaaaag aataaacatt
    85741 attttcttac gagaggttgt gacagagacg atcagcctat cagaataagg aggtgtgaca
    85801 cgatttttgt cacaccttct tttttgtata taaaaatccc aagtaaatac ataaaaaata
    85861 aaaaaattga aacttttagc gcaccttgta cgtcatatta agtgaggcag aaaggagtgg
    85921 agaatgattt ttactggata taagaaaaaa cggcagatcg aaaaataccg tcacctgctg
    85981 aatggactca tcgaaactga ttatcaaaaa atgttccgta tcacgatgaa ttacgtacat
    86041 gataaagaag aggccttaga tgtgatgcaa gatagttttc ataaagccct gaactatttt
    86101 gaaaaagaaa aagagatcga gcattttagt gcatggtttt atcggatatt gatccgcacg
    86161 gcattagata gttggcgcag acaaaaaagg acgcctgtgg acttatttga aattcaagat
    86221 atcccccaac agttaccttt agaaacttcc gttgcagagc tccatatgat tttagataaa
    86281 atagacagtc cggaaaaaga gattctgatc ctctactttt ttgaaggatt tcgtttgaaa
    86341 gaaattgcga ctatcttgga tatgaatgaa aacacagtta aaacgaaaat gtaccgctca
    86401 ttgaatgctt tacgtcaaat cctagaatga aggagagaag agtgccatgt attcccaaaa
    86461 agaaaattta aaaaaactaa agaaaactta taaagaacaa gcaattccca aagggcttaa
    86521 agaggagatc cgccagcgtt ttattatcga agagcaatca tttataaaag caaagcggag
    86581 aaagagacgt ctccaagggt tcggagtatc tttggctatc gtaatgatta caacaagtag
    86641 ccttcttttt aatagtcaag ttcgaagctt tgcagaagat ttacccatct taggatcagt
    86701 cattgaattg atcttaggcg aacgctttac tgatcgatct gaaaaaatcg atattcaggt
    86761 accgaagatc aatacacaaa atgagaaaga aaataaaaca attcatggat taaatcaaaa
    86821 atactttcgc gaaggacaag cagattttga aaaagctgaa aaagaatatg gaaattttga
    86881 aacggatcat taccaagttt tgggagatta tcagaaaatc gtagacgata accggtttct
    86941 cgtgattgaa aggcagatca cccaaacagc agcagatagc catgttgaaa aaagatacga
    87001 cacaatcgac aagaaaaaca gtgtccagct ctcacttcca cttttattca aagatgacac
    87061 ctatctatct gttttgacaa aagaagtcaa acggcagatg gccgaacaag tcaaggaaga
    87121 tccatctaag tactattgga ctgagcaaga tattcaagaa gggacgatag aaaaaccaac
    87181 acttgttacg cctacacgaa gtttttattt gaacaaagag catcaattag ttttgacttt
    87241 ttctcaatac gaaattgctc ctggttatat gggtacacca gaatttgtca ttcctaagtc
    87301 cgtgacaaaa acgattttgg catcggaaga ttatttggat cattagacga gaagtagttg
    87361 cgactagcag tttcaatttt caagtaagta caagtaaata ataagaagag aaaaagagaa
    87421 agaagagata tagtgaaaag aaattattta gttatcagta ttattgcttt atccgtgctt
    87481 ttgtttttcg aaattacttc ggtggcctcc ttgatcaccg aagtaaaagg acaaacacac
    87541 tcttcggagc attcgtcaca atctttcaaa caatcagaac aatcaaccat taaaagccaa
    87601 tcaactgaaa cagctaacgt caaagaagcc attcaagaat cagcggaaaa ggtacaaagt
    87661 cagtcatcac aatcaacaca agacagtaca aaaacgagcc gagatccggc tgtcaaaagc
    87721 gtcgcaatca gctttgatga tggaccagga gcgaccacaa caccgcagct tctgcgaatc
    87781 ttaaaagaaa aaaacgtgca tgccactttt ttcgtcttag gagaaaatac ggcgcagcat
    87841 cctgaaatcg tgaagcagac agctgaagca gggcacgaga ttggcaatca cacatacgat
    87901 catcagaatc tggccactct ttctgcccag tcgatgacgg aggaagtgac gaaagcagac
    87961 actgagatca aaaaagtcac tggcaaaacc cccacttttg ttcgtccgcc ctatggttct
    88021 gtcacgaatg taggagcaac gatcatccag cgaccgatca tcgaatggtc tgttgattca
    88081 gaagattgga agacaagaaa tcctgatttg attttgcaga agatccaagc aacagtatac
    88141 gatggggcaa ttattttatt ccatgatatc tatcctgaaa cgattcgtgc cgttcctcaa
    88201 gtgatcgatt atctgaaaga gcaagggtat cgcatcacga cagttgggga tttattaggg
    88261 catccaacgg ctgtcgagaa ctattatggc agaaacgatc atcggccagt tcagtaagtg
    88321 agacaagtat ctttaataaa taacacattt taataagtag ttgaacacat aactacctta
    88381 cttgcaaagg cttaacaata tctatacagg tacaacaaaa aactgtccac caattttctt
    88441 tggcggacag ttttcactta aaaataaaga agcaactatt cgtaaattat gctaaaatag
    88501 cagtagaacg cgtcctgagg gaatcgaacc cccgtctcaa gaaccggaat cttacgtgat
    88561 atccactaca ctaaggacgc aagcactggg ataattgtaa ctaaacagat aaaaaattac
    88621 aaggggattg gacaaaaaaa tgaaatttga gcaaaatttt tcacaaaaac agcagcagac
    88681 acagaaacta gccatgacgc aacagttgca acagtccatc caagttttac aatataacag
    88741 tgaggagctg ttggcattcg ttgagaatca agcaatggaa aatccattgg tggaagttgt
    88801 tgagccggaa tggcagccag attacataaa agcttcttca tcttcttatg aaggagaaga
    88861 gacaaattac ctaaatcaga ttcctgatac aaaagggtct ttatttgatt cattgatcga
    88921 acaagtccat ttgaattacc gagatacttt tttgaggaaa atcgttcttt atcttgtaga
    88981 atacatcgat ttgaacggat ttttgacgat tagtttagaa gaagccggaa aagagattgg
    89041 agctacgcct atccaaatgc tcgatgcgtt gactctgatt cagcaattag aaccagctgg
    89101 agtaggtgca cgtagtttgc aagaatgtct catgcttcaa acagaacgag atgattatgc
    89161 gccggaatta gcttatatcg tgttggaaga atgttttgag gaactggtgg agcgaaaatg
    89221 gaaagaaatc gcacaacgtt tttctgttga tctacatgct gttcagcaga tattcgacta
    89281 tttacaaacg ttgagtccaa gccctggccg gattttcgac cgtagcagcg aattgtacat
    89341 tattcctgat gtccgggtat tagtggacga cgataaaaat gtacaagtta tctcaaaccg
    89401 aaaaaatcag ccaaatatac gctttcaaga gagttacttc aaacaaatgt cacaacaagc
    89461 agataaagaa actgaaaatt atttaaaaga acggaaacag gaattcgaat ggttgaagaa
    89521 aacgatccta caacgtgggg atacaatttt gcgggttgct caagtcattg tttcccggca
    89581 aaaagctttc tttatcgaca aggaacgtcc aatcaagcct cttacgttaa aggaagttgc
    89641 aactgagata gatgtgcatg aatccacggt cagtcgtgca gtcaacggga aatatttgga
    89701 aacagacttc ggtgtatttg aattaaaaaa atttttcact acacgaattc ctacgaatag
    89761 tacagaacag acagaagacc tttcagcaga tacagcgaag aaaaagctgc aggaattagt
    89821 cgatcaagaa gacaaaaaca agccgttgtc tgaccagaaa ttggttgaat tgctgaaaaa
    89881 agatgagata gcgatctcaa gacgaacagt agcaaaatat cgtgatttat taggaatccc
    89941 gagttcatca aaaagaaaac gttatgataa ctaatcagtc aaaagactag aaaaagtatt
    90001 tcactttttc tagtcttttt agttgaaaaa cgagagcaaa actgttagac ttacagtcgt
    90061 gaggttgaga tttcccttta ttgatgtgaa attcgaatag ttaatttctt tttttatcgt
    90121 atatgggtcg ttttaagtct acattggacg taaagtgtcc aactaaggag atcgctatgc
    90181 tggatgaaat aaaaatgatt gaatctgttg caccagatat tatcgaagtg ttgcaagaac
    90241 gctataaaat tttacgaaat atctattgga tgcagccgat tggacgtcga agtttatcgg
    90301 aaagtatggg gatcacagaa cgagtattgc gaacagaaac agatcttttg aaaaatctga
    90361 atttgatcga cacctcaaaa agcggtatga cgctgacaac taagggcgaa gaagtttatc
    90421 aaagccttga aaacttcatg gatcagcttt taggtacgca tcaaaccgaa caacagttgg
    90481 cagaatattt tggtaaccaa cgctgtatcg ttgtttcagg aaacagcgaa gagcagacca
    90541 aagtggctga tgcattcggc gaagcgctga gcgaagccct agaccgacta cttccagaag
    90601 gcgagaatat catcgctgtg atgggaggaa ctactatggc tgtggtagcc gaacaattgt
    90661 ctaatctgga aaataagaaa cggcataacc tgtttgtccc tgcaagaggc gggattggtg
    90721 aagcgataac tgtacaggca aattctgtca gtgcaagaat ggctgctaaa gcaaacggta
    90781 accaccgtgc actttatgtt ccggaacaat taagtctggc aacttacaat tctttactca
    90841 atgagccatc tatccaagaa gtcttaaact tgattagtga agcgaattgt gttattcata
    90901 gtattgggcg tgcattacac atggcagcac gtcgtaagat gactgaaaaa gaattagtca
    90961 tgctgaaaca agcaaatgct gttgcggaat cttttggcta ctttttcaat gaaaaaggtg
    91021 aagtcgttta taaggtccct agaatcggca tagaattgca agatttggaa aaagtcccga
    91081 tcatcatggc aatcgcgggc ggaaaatcaa aagctaaagc aattcgagct tatatgaaaa
    91141 atgcaccaaa acaaacgtgg ctcatcactg atgaagctgc tgcaaatgag attttaaaag
    91201 gggtaaccct ttaaaataaa tatttttttg attttcataa ggaggaaatc ttaaatgaca
    91261 gttaaagtag gtattaatgg ttttggacgt attggacgtc tagcattccg tcgtatccaa
    91321 gatgtagatg gaatcgaagt agtagcaatc aacgacttga cagatgctaa aatgttggca
    91381 cacttgttaa aatacgacac aactcaagga cgtttcaacg gaacagttga agttcatgaa
    91441 ggttcattca acgtaaacgg aaaagaagtt aaagtattag ctaaccgcaa cccagaagaa
    91501 ttaccatggg gcgaactagg cgtagatatc gttctagaat gtactggttt cttcacttct
    91561 aaatcagcag ctgaaaaaca tttaacagct ggtgctaaac gcgttgttat ctctgctcct
    91621 ggcggaaacg atgttccaac aatcgtttat aacacaaacc acgaaacatt aactggtaaa
    91681 gaaacagtta tctcaggtgc ttcatgtact actaactgtt tagctcctat ggctaaaaca
    91741 ttgaacgaca aatttggtgt tgttgaagga ttaatgacaa ctatccacgc ttacacaggt
    91801 gaccaaatga ctctagacgg acctcatcct aaaggtgact tccgccgtgc acgcgctgct
    91861 gctgcaaaca tcgttcctaa ctcaacaggt gctgctaaag ctatcggttt agtaattcct
    91921 gaattgaacg gtaaattaga cggagctgct caacgtgttc ctgtaccaac aggttcatta
    91981 acagaattag taacagttct tgaaaaagaa gtaactgttg acgaaatcaa tgcagcaatg
    92041 aaagaagctt caaacgaatc ttacggatac aacacagacg aaatcgtttc ttcagatatc
    92101 gttggtatga cttacggttc attatttgat gctacacaaa ctaaagtaat gacagttggc
    92161 gacaaacaat tagttaaaac tgttgcttgg tacgacaacg aaatgtcata cactgcacaa
    92221 ttagtacgta ctttagaata cttcgctaac ttataagata gacaaacgta caagtgtaaa
    92281 ttatagacat gtacatttaa aagcggggaa gcaatcgcgc ttcttccgct ttttttgata
    92341 ataagtttat tcaggaggaa ataaaatggc taagaaaaca gtgaaagata tcgatttaaa
    92401 agacaaaaaa gttcttgtcc gtgttgactt caacgttcct ttgaaagacg gcgtgatcac
    92461 tgacgacact cgtatcaaag cagcattgcc aacaatcaac tacgttctag aacaaggcgg
    92521 aaaagcaatc cttttctctc accttggacg tgtaaaaaca gaagaagata aagaaggaaa
    92581 atctttagct ccagttgcaa aacgtctagg cgaattatta ggtaaagaag taacattcgt
    92641 acctgaaact cgcggagaac aattagaaga agcaatccgc aacatgaatg acggcgacgt
    92701 tgtcgtattc gaaaatacac gatttgaaga tattgacggt aaaaaagaaa gcaaaaatga
    92761 tacagaacta ggtaaatact gggcttcatt aggcgatgta tttgttaacg atgctttcgg
    92821 tacagctcac cgtgcacatg cttctaacgt aggtatcgct tcaactggta tcccaacagt
    92881 tgctggattc ttgatggaaa aagaaatcaa gttcatcggt gaagcagtag aagaaccaaa
    92941 acgaccaatg attgcaatcc ttggtggcgc aaaagtttct gataaaatcg gcgtaatcga
    93001 aaacttgatt cctaaagcag ataaaatctt gatcggtggc ggaatgactt acacattcta
    93061 cgaagcaaaa ggaatcaaga tcggtaactc tctagtagaa gctgataaag tggaactagc
    93121 aaaagaatta atcgaaaaag caggcgacaa acttgtcttg ccaatcgaca atgtctgtgc
    93181 accagaattt tcaaatgatg ttgaaacaca agtaatcgaa ggagacattc ctgatggttt
    93241 gatggcttta gacatcggcc cagcatcagt aaaattattt gctgatacat tacaaggtgc
    93301 aaaaacagtt gtttggaacg gacctatggg tgtatttgaa atgagtaact ttgctaaagg
    93361 tacaatcggt gtttgtgaag caatcgctaa cttagaaggc gcaacaacaa tcatcggtgg
    93421 cggagactca gccgcagcag cagaacaatt aggatttgct gacaaattca cacacatctc
    93481 aacaggtggc ggcgcaagct tggaattgct tgaaggtaaa gaattaccag gactagcagc
    93541 aatcaacgat aaataaacga ccaagtttgc tcaattctga cgagtaatcg aacaaaaggt
    93601 gaagggagtt ttcatgactc cctagccatt tttcaataaa ttaaggagtg tgttcctcaa
    93661 tgcgtaaacc tattatcgca ggtaactgga aaatgaacaa aactgcatca gaagcaaaag
    93721 aatttgctga agcagtaaaa aacaaaatcc cttcaaatga caaagttgat tcagtcatcg
    93781 gatctcctgc attattctta caagaattaa tgacatcagc tgaaggtaca gaactaaaaa
    93841 tctcagcaca aaactgctac tgggaaaact caggtgcgtt cactggtgaa acttcaccag
    93901 cagctcttgc tgatctaggt gttcattatg tgatcatcgg acattcagaa cgtcgtgaat
    93961 atttccatga aacagacgaa gacatcaata aaaaagcgaa agctatcttt gcaaatggta
    94021 tgacaccaat cctatgctgt ggcgaatctt tagaaaccta tgaagcaggc aaaactgctg
    94081 aatggatcga aggacaaatt acagctggtt tagctgatct ttcagctgaa caggtgtcaa
    94141 acatggttat tgcttatgaa ccaatctggg caatcggtac tggtaaatca gctgacgcac
    94201 aaatcgctga cgaaatttgt ggagttgtac gtcaaacagt tgaaaaactt tatggaaaag
    94261 aagtatcaga agcagttcgt atccaatacg gcggttctgt aaaaccagaa aatattgctg
    94321 aatacatggc aaaagaaaat gttgacggtg ctttagtcgg tggcgcaagc ttgcaagcag
    94381 attcattctt gtcattgtta gacgctgtaa aataattgtt gaaaatttgc gaaaaatgca
    94441 agaaatgttt gcactaatga gcaaaattaa ctaaaatcgt atatgaggga aatcccttag
    94501 gaaaaaacaa actcaaagga gagacaaaac atgtcaatta ttactgatgt ttacgctcgc
    94561 gagatcttag actcacgtgg taacccaaca atcgaagtag aagtatacac agaaagcgga
    94621 gcttttggcc gcggaatggt tccttcaggt gcttcaactg gtgaatacga agcagttgaa
    94681 ttacgtgacg gagacaaagc tcgttatggc ggtaaaggtg taactaaagc tgtcgacaac
    94741 gtaaacaaca tcattgctga agcaatcatt ggctacgatg ttcgtgacca aatggctatc
    94801 gacaaagcta tgatcgcttt agacggaact cctaacaaag gtaaattagg tgcgaacgct
    94861 attttaggtg tttctatcgc tgttgcacgt gcagctgctg actacctaga agtaccttta
    94921 taccactacc taggcggatt caacacaaaa gtattgccaa caccaatgat gaacatcatc
    94981 aacggcggat cacatgctga taactcaatc gacttccaag aattcatgat catgcctgtt
    95041 ggcgctccaa cattcaaaga agctctacgt atgggtgctg aagtattcca cgcattagct
    95101 tcaatcttga aagctcgcgg attagcaact tctgttggtg acgaaggtgg atttgctcca
    95161 aaccttggtt caaacgaaga aggttttgaa gtaatcatcg aagcaatcga aaaagctggc
    95221 tatgtacctg gtaaagacgt tgttcttgct atggatgctg cttcttcaga attctacgac
    95281 aaagaaaaag gtgtttacgt actagctgat tcaggcgaag gcgaaaaaac aactgacgaa
    95341 atgatcaaat tctacgaaga attagtttct aaatatccaa tcatctcaat cgaagacgga
    95401 ttagacgaaa acgactggga cggattcaag aaattaactg acgtattagg cgacaaagtt
    95461 caattagttg gtgacgactt gttcgtaaca aacactcaaa aattatctga aggtatcgaa
    95521 aaaggaattg ctaactcaat ccttatcaaa gtgaaccaaa tcggtacatt aacagaaact
    95581 ttcgaagcta tcgaaatggc taaagaagct ggctacacag cagttgtatc tcaccgttct
    95641 ggtgaaacag aagattcaac aatctctgat atcgctgttg caacaaacgc tggccaaatc
    95701 aaaactggtt ctctatcacg tactgaccgt attgctaaat acaaccaatt actacgtatc
    95761 gaagaccaac ttggtgaagt tgcagaatac aaaggtttga aatctttcta caacttaaaa
    95821 aacaaataat tcttttctaa tgaagataca tgatcgacta ttgaaagata gtcgagtatg
    95881 atcacttagt taagtaatcg aactctctac ttgctgaaat atcagcaggt agagagtttt
    95941 tttgcaacta gcttctgtat atgatgttta caaagaatgg tacaagaaaa gatcatcctt
    96001 gaaaaaggaa agctaacaat aactagcatc atataagagc ttttaaggat agaacagtag
    96061 aataggaatc tatgagcaag tcctctcgta taaataaaat aggagggaag tagcagcata
    96121 tttttcataa agtggctctc tttcttcatt tttactttgg ttgctcctat ttgaaaattc
    96181 gagcacactc aaatacaata aaaagaaatg gcaagggaga ggattagatg aaaaaagaag
    96241 aaaaaatcgc gattttacaa gagatcatcc gaattaaatc agtgaatgga aacgaaggtg
    96301 aagtagcagc ctatttgaat aagcttttgg caaagcatga cataacagga gagattgttt
    96361 cttacagaga tggtagagat aatttgattg ctcgttacca aaagggccaa tcaggaaaag
    96421 tgttaggcct atctgggcat atggatgtcg tggcggctgg tgatgaatcg tcttggacct
    96481 atgcaccctt tgcagcagaa atccatggga accgtttgta cggacgtggt gctacagata
    96541 tgaagagtgg cttggcagca atggtgattg ccatgatcga actgaaagag tcaggaaaac
    96601 catttaacgg aacagtcaaa ttattagcca ctgtcggaga agaagtgggt gaactaggtg
    96661 gggaacagct cacgaaagca ggctatgtag atgacttaga tgccttgatc atcggagagc
    96721 caaccaatta cagtttgatg tatacgcaca tgggatcaat caactataca gtcacctcgc
    96781 acggaaaaga agcgcatagc tctatgccag accaaggtta taatgcaatc aatcacctaa
    96841 atgaattcat tacgaaagca aatgctgaaa tgaatcacct cgctgaaaca atcgagaatc
    96901 ctgtcctagg aaaaacaatc cataatgtta cattgatcag tggcgggaat caagtcaaca
    96961 gcatcccaag ccatgcgcag ctccaaggga acattcgatc gattccagaa tacccaaatg
    97021 ataaaatcat tgcattgctg caatcaatcg tcaatgaatt gaatcaagag acagactatc
    97081 atttggaatt gatgatcgat tacaacaaaa tacctgtcaa agctgatcca gattctcctt
    97141 tgattcattg cattcagcaa caattcagcc agccattacc tttagttgga gcggcagcaa
    97201 caacggatgc agccgaattt acgaaagcta accattcctt cgactttgtc gtctttgggc
    97261 ctggtgtcgt tactttgcct catcaagtag atgagtatgt tgaaatcgat aattatttgg
    97321 atatgatcga aaaatatcaa ggaattattt tatcctactt agcgtaagat ttttttaata
    97381 aatgaaaaaa cagagccaga ttagcatta
//
LOCUS       DAZUJR010000002        84650 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.002, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000002 DAZUJR010000000
VERSION     DAZUJR010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 84650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 84650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..84650
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.002"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(59..187)
                     /locus_tag="ACG804_000100"
     CDS             complement(59..187)
                     /locus_tag="ACG804_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFS4831069.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="ACG804_000101"
     CDS             complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="ACG804_000101"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFS4831070.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(1674..2729)
                     /locus_tag="ACG804_000102"
     CDS             complement(1674..2729)
                     /locus_tag="ACG804_000102"
                     /EC_number="2.7.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HFS4831071.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="ACG804_000103"
     CDS             complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="ACG804_000103"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HFS4831072.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="ACG804_000104"
     CDS             complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="ACG804_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HFS4831073.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKATFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="ACG804_000105"
     CDS             complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="ACG804_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HFS4831074.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="ACG804_000106"
     CDS             complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="ACG804_000106"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HFS4831075.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTVKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="ACG804_000107"
     CDS             complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="ACG804_000107"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HFS4831076.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLANPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            10491..12050
                     /locus_tag="ACG804_000108"
     CDS             10491..12050
                     /locus_tag="ACG804_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HFS4831077.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQKVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(12161..14092)
                     /locus_tag="ACG804_000109"
     CDS             complement(12161..14092)
                     /locus_tag="ACG804_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HFS4831078.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAAAEA"
     gene            complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="ACG804_000110"
     CDS             complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="ACG804_000110"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HFS4831079.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(15021..15773)
                     /locus_tag="ACG804_000111"
     CDS             complement(15021..15773)
                     /locus_tag="ACG804_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFS4831080.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLFNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(15932..16141)
                     /locus_tag="ACG804_000112"
     CDS             complement(15932..16141)
                     /locus_tag="ACG804_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831081.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(16152..17480)
                     /locus_tag="ACG804_000113"
     CDS             complement(16152..17480)
                     /locus_tag="ACG804_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831082.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            17616..17771
                     /locus_tag="ACG804_000114"
     CDS             17616..17771
                     /locus_tag="ACG804_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HFS4831083.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(17845..18432)
                     /gene="yihA"
                     /locus_tag="ACG804_000115"
     CDS             complement(17845..18432)
                     /gene="yihA"
                     /locus_tag="ACG804_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HFS4831084.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="ACG804_000116"
     CDS             complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="ACG804_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HFS4831085.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVERAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(20012..21301)
                     /gene="tig"
                     /locus_tag="ACG804_000117"
     CDS             complement(20012..21301)
                     /gene="tig"
                     /locus_tag="ACG804_000117"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HFS4831086.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(21455..22387)
                     /locus_tag="ACG804_000118"
     CDS             complement(21455..22387)
                     /locus_tag="ACG804_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831087.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLNEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(22544..23203)
                     /locus_tag="ACG804_000119"
     CDS             complement(22544..23203)
                     /locus_tag="ACG804_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HFS4831088.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSIYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAIFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="ACG804_000120"
     CDS             complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="ACG804_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HFS4831089.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELASNVLEEGDSTQKIVKLSVDGTIAAGGASGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAMR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(24244..24534)
                     /locus_tag="ACG804_000121"
     CDS             complement(24244..24534)
                     /locus_tag="ACG804_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831090.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAEAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            24944..26749
                     /gene="glmS"
                     /locus_tag="ACG804_000122"
     CDS             24944..26749
                     /gene="glmS"
                     /locus_tag="ACG804_000122"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HFS4831091.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDSSDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(26821..28176)
                     /gene="glmM"
                     /locus_tag="ACG804_000123"
     CDS             complement(26821..28176)
                     /gene="glmM"
                     /locus_tag="ACG804_000123"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HFS4831092.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(28200..29369)
                     /locus_tag="ACG804_000124"
     CDS             complement(28200..29369)
                     /locus_tag="ACG804_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HFS4831093.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(29366..30253)
                     /gene="cdaA"
                     /locus_tag="ACG804_000125"
     CDS             complement(29366..30253)
                     /gene="cdaA"
                     /locus_tag="ACG804_000125"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HFS4831094.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="ACG804_000126"
     CDS             complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="ACG804_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HFS4831095.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIVPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPAMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLENANPN
                     LAKALFEKTIQDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARAERRKKMEQATKEKKEK"
     gene            34320..34841
                     /locus_tag="ACG804_000127"
     CDS             34320..34841
                     /locus_tag="ACG804_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HFS4831096.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLSCPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(35540..36105)
                     /locus_tag="ACG804_000128"
                     /pseudo
     CDS             complement(35540..36105)
                     /locus_tag="ACG804_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(36284..36940)
                     /locus_tag="ACG804_000129"
     CDS             complement(36284..36940)
                     /locus_tag="ACG804_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831097.1"
                     /translation="MRFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLRAGLITFIS
                     IVGFFLFTVIVFIWRTPAPPLPEITYGEFPFRLEYELNEELHVIEDTLIVEFDGFGMN
                     EGIGRYRRWTSRLASGEDLVLLLEVSDNKQIFYFPGPANYYMGDRLNGYNHTFPSASF
                     IERERGITRRDILHDKELLEQFGPLDQNTINEEELLNQYNIRLVNWEISEPIVNNFGD
                     "
     gene            complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="ACG804_000130"
     CDS             complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="ACG804_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HFS4831098.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(38477..39475)
                     /gene="yvcK"
                     /locus_tag="ACG804_000131"
     CDS             complement(38477..39475)
                     /gene="yvcK"
                     /locus_tag="ACG804_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine diphosphate-N-acetylglucosamine-binding
                     protein YvcK"
                     /protein_id="HFS4831099.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAIDR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="ACG804_000132"
     CDS             complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="ACG804_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HFS4831100.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(40491..41222)
                     /locus_tag="ACG804_000133"
     CDS             complement(40491..41222)
                     /locus_tag="ACG804_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HFS4831101.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLQPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTVLQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSKALDTASEK"
     gene            complement(41226..42491)
                     /locus_tag="ACG804_000134"
     CDS             complement(41226..42491)
                     /locus_tag="ACG804_000134"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HFS4831102.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="ACG804_000135"
     CDS             complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="ACG804_000135"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HFS4831103.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQDIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="ACG804_000136"
     CDS             complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="ACG804_000136"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HFS4831104.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKNAAKALDFETAANVRDMILELKASK"
     gene            47833..49335
                     /locus_tag="ACG804_000137"
     CDS             47833..49335
                     /locus_tag="ACG804_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HFS4831105.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            49337..50074
                     /locus_tag="ACG804_000138"
     CDS             49337..50074
                     /locus_tag="ACG804_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFS4831106.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(50119..50292)
                     /locus_tag="ACG804_000139"
     CDS             complement(50119..50292)
                     /locus_tag="ACG804_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831107.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            50304..50933
                     /locus_tag="ACG804_000140"
     CDS             50304..50933
                     /locus_tag="ACG804_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4831108.1"
                     /translation="MGQLSDNQQLCQERINPLLELLERVFSYYGQALLTVHRQQIIIL
                     VNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSFLHAKQVCEWIAF
                     HQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLFKKTLACFSKNNG
                     SIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLLVQT"
     gene            complement(51015..52181)
                     /gene="dnaJ"
                     /locus_tag="ACG804_000141"
     CDS             complement(51015..52181)
                     /gene="dnaJ"
                     /locus_tag="ACG804_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HFS4831109.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(52332..54161)
                     /gene="dnaK"
                     /locus_tag="ACG804_000142"
     CDS             complement(52332..54161)
                     /gene="dnaK"
                     /locus_tag="ACG804_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HFS4831110.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            complement(54212..54775)
                     /gene="grpE"
                     /locus_tag="ACG804_000143"
     CDS             complement(54212..54775)
                     /gene="grpE"
                     /locus_tag="ACG804_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HFS4831111.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            complement(54869..55912)
                     /gene="hrcA"
                     /locus_tag="ACG804_000144"
     CDS             complement(54869..55912)
                     /gene="hrcA"
                     /locus_tag="ACG804_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HFS4831112.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            complement(56146..57312)
                     /gene="hemW"
                     /locus_tag="ACG804_000145"
     CDS             complement(56146..57312)
                     /gene="hemW"
                     /locus_tag="ACG804_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HFS4831113.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNAHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            complement(57328..57555)
                     /locus_tag="ACG804_000146"
     CDS             complement(57328..57555)
                     /locus_tag="ACG804_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HFS4831114.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            58039..58646
                     /locus_tag="ACG804_000147"
                     /pseudo
     CDS             58039..58646
                     /locus_tag="ACG804_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313657.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase family
                     protein"
     gene            58819..59532
                     /locus_tag="ACG804_000148"
     CDS             58819..59532
                     /locus_tag="ACG804_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831115.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(59647..60657)
                     /locus_tag="ACG804_000149"
     CDS             complement(59647..60657)
                     /locus_tag="ACG804_000149"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="HFS4831116.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(60694..61176)
                     /locus_tag="ACG804_000150"
     CDS             complement(60694..61176)
                     /locus_tag="ACG804_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HFS4831117.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            61326..61694
                     /locus_tag="ACG804_000151"
     CDS             61326..61694
                     /locus_tag="ACG804_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HFS4831118.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            62159..62611
                     /locus_tag="ACG804_000152"
     CDS             62159..62611
                     /locus_tag="ACG804_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4831119.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(62735..63586)
                     /locus_tag="ACG804_000153"
     CDS             complement(62735..63586)
                     /locus_tag="ACG804_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HFS4831120.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(63599..64384)
                     /locus_tag="ACG804_000154"
     CDS             complement(63599..64384)
                     /locus_tag="ACG804_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFS4831121.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            complement(64736..65677)
                     /gene="ribF"
                     /locus_tag="ACG804_000155"
     CDS             complement(64736..65677)
                     /gene="ribF"
                     /locus_tag="ACG804_000155"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006747 - FAD biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009398 - FMN biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HFS4831122.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            complement(65681..66604)
                     /gene="truB"
                     /locus_tag="ACG804_000156"
     CDS             complement(65681..66604)
                     /gene="truB"
                     /locus_tag="ACG804_000156"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HFS4831123.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            complement(66972..69334)
                     /locus_tag="ACG804_000157"
                     /pseudo
     CDS             complement(66972..69334)
                     /locus_tag="ACG804_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase"
     gene            69499..69955
                     /locus_tag="ACG804_000158"
                     /pseudo
     CDS             69499..69955
                     /locus_tag="ACG804_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035543.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
     gene            complement(70112..70459)
                     /gene="rbfA"
                     /locus_tag="ACG804_000159"
     CDS             complement(70112..70459)
                     /gene="rbfA"
                     /locus_tag="ACG804_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HFS4831124.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(70486..72792)
                     /gene="infB"
                     /locus_tag="ACG804_000160"
     CDS             complement(70486..72792)
                     /gene="infB"
                     /locus_tag="ACG804_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HFS4831125.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(72805..73116)
                     /locus_tag="ACG804_000161"
     CDS             complement(72805..73116)
                     /locus_tag="ACG804_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HFS4831126.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(73113..73406)
                     /locus_tag="ACG804_000162"
     CDS             complement(73113..73406)
                     /locus_tag="ACG804_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HFS4831127.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(73428..74603)
                     /gene="nusA"
                     /locus_tag="ACG804_000163"
     CDS             complement(73428..74603)
                     /gene="nusA"
                     /locus_tag="ACG804_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HFS4831128.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(74626..75099)
                     /gene="rimP"
                     /locus_tag="ACG804_000164"
     CDS             complement(74626..75099)
                     /gene="rimP"
                     /locus_tag="ACG804_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HFS4831129.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(75244..79602)
                     /locus_tag="ACG804_000165"
     CDS             complement(75244..79602)
                     /locus_tag="ACG804_000165"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HFS4831130.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            complement(79814..81523)
                     /locus_tag="ACG804_000166"
     CDS             complement(79814..81523)
                     /locus_tag="ACG804_000166"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HFS4831131.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTNLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELVNTLPILLN
                     QGE"
     gene            complement(81591..82859)
                     /gene="rseP"
                     /locus_tag="ACG804_000167"
     CDS             complement(81591..82859)
                     /gene="rseP"
                     /locus_tag="ACG804_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HFS4831132.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAILLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPDKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(83020..83820)
                     /locus_tag="ACG804_000168"
     CDS             complement(83020..83820)
                     /locus_tag="ACG804_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HFS4831133.1"
                     /translation="MKQRVVTAAVALVLFIPIIWIGGIAVELTAAILAVIGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(83817..84629)
                     /locus_tag="ACG804_000169"
     CDS             complement(83817..84629)
                     /locus_tag="ACG804_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HFS4831134.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
BASE COUNT        23254 a        18313 c        14778 g        28305 t
ORIGIN      
        1 taaaaagact aagaaacaat aacaaaagtt aacacttctt agtctttctt tagcacgtct
       61 atttattaaa gattttaggg ccttttctca tgtttttacg atcattctta ggtgtttcca
      121 tttgtttgga tcggcctcca ccttgtttct ttttgatcaa ttctttcatt ttttcttttt
      181 ggtccatttt tattctcctt taacgaatga agcgactaat tcgatatgat gggtttgcgg
      241 gaaaagatct acaggctgaa ctttcttcac ggcataacct gcttctgcaa ataacttagc
      301 atctcttgca aaagttgccg gattacatga gatatagacg attcgttctg gtgacatttc
      361 gattgctgat tcaataaaat gatgatctaa tccttttcgt ggagggtcaa ctacgatcac
      421 agatggtttg atcccttttt cttgccattt tttcataact ttttctgctt ttccgacttc
      481 ataatgaaca ttttcgattt tattatttaa agcattgaac tgtgcatctt caattgcttc
      541 tggaataact tccatcccat acaccttatc cactctgtct gctaaagaca agccaatcgt
      601 acctattcct gaataagcgt cgatcacaat gtctttttta tctaactcgg caaactcgat
      661 ggctgtttgg tacagatact ctgcttgttg agtatttact tgataaaatg actttgctga
      721 gattcgatag gtttttccta atagctgatc ttcgatatag tctctgccat ataaaacttt
      781 ttctttgtct cctaaaatca catttgtttt ttcttcattg atattttgga tgaccgaaac
      841 cacttctggc aattcttcat gaatagcttc agcaatttcc ttggatttaa agaatttttc
      901 tttacgagta actaaaacga ccatcatttc atgggaataa tgaccacgac ggataatgat
      961 gtgacgaagc tgtccttcat ttttttcttc attatatcct cgtacttgga accgttgcaa
     1021 gatatctctg actactttga ttgcttgatc gatgacagga tcttggatat aaaaatcttc
     1081 gatagggact agatcatggc tattcttttt gtaaaaaccg gtggctaact gtccatcgat
     1141 acggcgaaca gggatctgtg ctttattacg gtagccgaat ggttctgcca ttccgaccgt
     1201 tggaagtaca ggaacttctg gcatcttagc aatcttcgcc attacatgct ctacttgttt
     1261 ttgtttgaag acaagctgtt gttcatactt caaatgggct aaaggtgcga tacctatgcg
     1321 aagtaatgca ttgttttcta caggctgacg atcaggtgat tgtgtaataa atgtttcgac
     1381 ttttccatat ccaaacttat tgcctgcttt tactactagt atttctactt cttctccagg
     1441 gagtgcattt tcgataaata atggataacc atcgattttt gctaccccca ttccttcata
     1501 actcaagtcg acgatttcga ctgtatatcg ttcgtttttc tttactattt gctgttctgt
     1561 catattttgc tcctttaagc ctatttttca atcctactga actctactat aaatcagcta
     1621 attacacaac taaaaccggc actgacctta ctacgttcag caccggcttt tgattaattc
     1681 ttttgattag gtgtttcgtc tgctattttt ccgtcaccgt cgatatcttc atccgttaaa
     1741 cgttcgactt cttttacgaa ttctttgctg acaacctcta attcttcttc atctgtacct
     1801 gtgattgctt catcaggaat ctgatcggta ttggcaaaga actcaatgtg ttgatgaaga
     1861 ttttggaaat gcatcggtgc ttccccgccg tattcaccat ctaagttgat cattactggt
     1921 cgattgatat catcttctgt ttcaacgaac aaactgcttg ttttggtata gattattctt
     1981 ggatcatcga catgtcgacc gccattcagc atgagtgctg caatatgcaa gatctcaaag
     2041 atatttgctg tcttcacaat gattaaagaa aacttcccat catccaattt ggcatctggc
     2101 gcgatctgtt cgaatcctcc aacagagttc gtcagcccta ggaaaaacat cgaagcattt
     2161 ccgatatatt ccccttcatc atacttcaag cgcattttga ttggctttac tcgagggagc
     2221 atctctgctc ctttcgcaag ataagcaaga taaccaaaaa tactctttag ttctgatgga
     2281 acttcataag tcaattctgt caaatagcca cctgcagcga tattgatgaa gtaactgtta
     2341 tcagaaaggc cgatgtccat ttttacggtt tggtgttttt ttatcacttc tgctgctgct
     2401 ttaatattat ctctaggaat ttttaatgct cgagcatagt cgttcgttgt accagctggg
     2461 atgatggcca ttttaggacg gtgttcaagc ggagcgattc cattaaccac ttcgttgatt
     2521 gtgccatcgc caccagctgc cactactaga tcaaaaccta gttctgcgac tctacatgct
     2581 tcattcttgg ctgaatctgg ttctggtgta gttgcatagg cgctggcttc aaatcctgct
     2641 tcttctaatg cctgtaggat atccgccaaa ttttttttca ataattcttt tcccgaggtg
     2701 gggttataaa ttacgcgtgc ttttttcatt ttcagcctct atcgtttcgc taattcatct
     2761 ttaagtagct tattcacgac accaggattt gcttgtcctt tagttgcttt catgatttga
     2821 ccgactagga agccaaccgc acgatctttt ccatttttga aatcatcgac agattgttgg
     2881 ttgttatcca aaatttcatt aatgattggc agtagtttgt tcggatcaga taattgcacc
     2941 caaccatttt tttcaactac ttcttgggct tctccgccat ttgtgatcaa ttcacggaag
     3001 acttttttgg cgatttttga gctgatcgtt ccatcggcga tcaaacgaat cattcctgct
     3061 aagttctcag gtgtcaattt tgtctcagct aattccagtt tctcactgtt caagtaagca
     3121 gaaacttcac ccatcaacca gttagatgct tgcttggcat ctgcaccatt ttccaaaaca
     3181 gcttcaaaaa aatcagacat ttcttttgta agtgtcaata ccattgcgtc atactctgga
     3241 agtccaaact cacggatata gcgttcgcga cgagaagctg gcatctcagg caaactagct
     3301 tttacttttt gaatccattc gtcatcgatc acgaatttcg ggatatcagg ctctgggaag
     3361 taacgataat cactagaccc ttctttgaca cgcatcaaaa ctgttttatt cgttgtttcg
     3421 tcaaaacggc gtgtttcttg ttggatttct cctcctgaaa gaagaacttt tgcttgacgt
     3481 ttttcttcaa aagctaaacc ttttttcacg aaagataaag agttcaagtt tttcaattct
     3541 gctttcgtac cgaactcttc ttgtccataa gggcgaagag aaatattggc atcacagcgc
     3601 atagagcctt cttccatttt cacatcgctg acttctgtaa attggataat tgatcgcaat
     3661 gcttctagat aagcgtatgc ttcttctggt gaacgcatat cagcttcaga aacgatttcg
     3721 atcaaaggcg tgccttgtcg gttcaaatca acgtaagaat aaccgccaat accatgcatg
     3781 ttttttccag catcttcttc taaatggaca cgttcgatcc ggattttttt ctttttacct
     3841 tctacttcga tttcgatcca tccgtcatga ccgattggtt gatcaaattg ggaaatttga
     3901 tatgcttttg gattatctgg gtaaaagtaa tttttccggt caaaatgagt atctttagag
     3961 atttcacagt ttaatgccaa agctgctttc atcccgaatt ccagcgcagc tttattcatt
     4021 actggcagca cgcctggata accccagtcg atcacgtttg tattgctgtt tggttctgca
     4081 ccaaaatgag ctggcgctgg agagaaaatt tttgagttgg tttttaactc gacgtggact
     4141 tctagtccaa tgactgtttc aaaattcatt cgtctttccc tcctaaaata gctggttgtt
     4201 gtttatggaa ttctgttgct tgttcaaacg catatgccgc ttgatacatc gttttttcat
     4261 caaaataatt accgatgatc tgcaatccaa ctggtaatcc ttctgataaa cctgccggta
     4321 cagacatacc tggaagtcca gccaagttga cagggatcgt taagatgtca ctcatgtaca
     4381 ttgtgattgg atcgttaatg ttctcaccga ttccgaatgc aactgttggt gaagatggcc
     4441 cgatgatcaa gtcataatct gcaaagactt tttcaaaatc tcgtttgatc aatgtacgga
     4501 cttgtcccgc ttttttgaag taagcgtcat aataaccagc acttaaggag aatgtaccta
     4561 acatgatacg gcgttttact tcttcaccga atccttctga acgtgagttg acatatacat
     4621 catctaatga tttcacattt tctgagcgat aaccgtagcg gataccatcg aatcgttgca
     4681 agttggaact tgcttctgat gaggcaatga tataataaac agccacaccg tattttgaat
     4741 gaggcaagct gacttcttcc acaacagcac ctaatgaacg gaatgtttct gctgctttca
     4801 atacagcttc ttttacgcca ggggccacac cttcgcctaa gtattcttta ggtaaagcaa
     4861 tcttcattcc tttgatgtcg cctgtcagtc cctctgcaaa atcaggaact gaaacgcctg
     4921 aagaagtacc gtctttttcg tcataaccgc tgatagctgt caatgctaat gcattatctt
     4981 tcaccgtacg ggtcattggt ccgatttggt caagagatga agcaaaggca atcaaaccaa
     5041 aacgtgagac acggccataa gtaggtttca tccctacgat gccgttaaaa gctgctggtt
     5101 ggcggatact tcccccagta tcactaccta aagaaactgg aatttgtcca gctgcaactg
     5161 ctgctgcaga accaccagaa gagccaccag gtacttttgt tgggtcccaa gcattttttg
     5221 ttttcttgaa ataagaagtt tctgtacttc cacccatagc aaattcatcc atgtttagct
     5281 taccaacagg gatcatatct gcttgataga ttttatccat gaccgttgca tcataaattg
     5341 gttcaaaatt gtaaaggatc ttagatgcag cggttgtcaa gatatctttt gttacgatat
     5401 tatccttgat accaattgga ataccagcaa ggacgttgct ttcatcaatc cctttttcat
     5461 ctaaagcttt tgcctgttcc aatgcttttt cttcgttcaa tgtaatgaat gcttcgacct
     5521 caggctctgt ttctttgatt cgttcaaatg ttgcttttgt caaatcttgt acagtgattt
     5581 ctttcgatac aagcatatga tgcagttctt ctagagaacg attgtgtaat tctgtcatta
     5641 tgcgccagcc tccccattat cgatgattgc gggtactttg ataaagccgt cttctgtttc
     5701 cggcacattt ttcaataatt catcgcggtt ccatccagct tgcgcccgat cttgtcgcat
     5761 cacgtttact gtttcaacca cattcgacgt aaatggaaca ccttctgtat ctacttcttc
     5821 cagcatttca accatatcga tgattttacc taattggtcg gtaaaacttg caagttcttc
     5881 atctgcgaac gcaagttttg ctaatttggc aacgtgtttc acttgttctt cactaatcgc
     5941 catactaccc cttctttcta aacgagttaa aaactttgct ctctatttta acacaagagt
     6001 gccgtgtctg aaattgttta ttgaaatttg tctgaaaaaa ctcatttttc attcttctac
     6061 tgagcgactt ttagccaatg catctgccat ttgatcttct gtccaaactt cgattcctaa
     6121 ttcttgtgct ttggtcagct tgctgccagc atcttctcct gctaccacga tatccgtttt
     6181 tttcgatacg ctaccagtca ctttcccgcc aagattttcg atcgtctctt ttgcttcttc
     6241 acgagtaaat cgtgttagtt taccagtaag gactactgtt ttttctttaa aaggagactc
     6301 gacttcttgc aattgggcat ttcgaagccc tttgtattcg aaattgacgc ctgcttgttt
     6361 taattcattc atcaattcat ggacttcttc gttactgaaa taagtgacta cactgtcggc
     6421 aatgatatca ccgatcgtat caagcgcaat aatcgactca tagtcacttt tactcaatgt
     6481 ttctagatca ccgaaatgtt ctgctaaaat ttttgctgct ttcgctccga catgtcggat
     6541 tcctaacccg aaaatcaacc gctcgaccga attatctttg ctgttgtcga ttgctgtcaa
     6601 aatattattt gctgattttt cttttatttt gtccaacgtc aataactctt cttctgtcaa
     6661 tttgtaaaga tcagcaacat ctgctactag ttttttatca tacatctgtt ctagtacgcg
     6721 cggccccaac ccatcgatat tcatcgcatt tcttgaaaca aagtggttca aaccttcttt
     6781 catttgagca gggcatttag gattgatgca ccgtaaggct acttcttcat ccaaatggac
     6841 aagttcactt ccacaaactg gacaatgtgt aggcaattgg tattcttcgc tgtctttagg
     6901 tcgtttatct aacacgactt gcgaaacttc tgggatgatg tctcccgctt tataaatcag
     6961 aactgtatct ttcaagcgga tatccttcaa cttaatataa tcaccgttat gcaggctggc
     7021 acggcttact gtcgttcctg ctactcggac tggtgtcatg atagctgttg gcgttactac
     7081 ccctgttcga ccgactgtcc attcgatgtt ttcgattagc gtttcaactt cttctggcgg
     7141 aaacttgtaa gctgctgccc atctcggtgc tttgacagta aaaccaagtt gatcttgtag
     7201 cgagaattca ttcactttga tgacgattcc atcgatttca tagggcaaat ccacacgttt
     7261 gtcatgatat tcttcaatgt atgaccacac ttcatcaatc gaatgacata gacgtttttc
     7321 ccgattcgtg tggaatccaa ttttttctag ctcttctagc gcatcatact gggtttttgc
     7381 ttgcatagga ccgaaatcag ctactgtgta taaaaaagtg tccagatttc ttttcgctgt
     7441 gattttagaa tctaactgac gcaaagaacc agctgcggcg ttccgaggat tcgcaaagat
     7501 atcttttccc tctgcttctc tgtcttggtt caattggaca aatgaccgtt ttggcatgaa
     7561 acattcgcct cttacttcga tgttcattgg ttcttttaat ttgattggga ccgaccggac
     7621 agtttttagg ttttcagtga tgttttctcc tacagttcca tccccgcgag tcgcacctct
     7681 cacgaaattt ccatcttcat aacgcaaaga aacggaaagt ccatctattt ttagttcaca
     7741 gcaatagtca actacacgtc ccactgcttt ttgtacacgt tgatcaaaag ctatcagctc
     7801 ttctttgctg aaaacgtcgt tcaaactgta aagcggaata tcatgagtga ctttttcaaa
     7861 accttctaat acttttccgc ctactcgttg agtgggagaa tcagacgtga tcaaatcagg
     7921 atattgttcc tcaattgcta ctaattctgc gtattcttta tcataaacat agtcttccac
     7981 tgttggttta tcttctacgt agtattcgcg agaccattgg ttcagtcttg tacgaagttc
     8041 ttctgctcgt ttagcagctt cgtcaatcgt catttcatgt tccatcattt accctccact
     8101 actaagcttt ttcaattggc gcaaaggcag ccaaaagacg ttttactcct tgacttggga
     8161 aagccacatc tagttctaga tccttcgacg tcccgcttac tcggacgact gttcctagac
     8221 cccatttttt gtgtttgact ttatctccag gtttccagct gttattttcc cctccagtag
     8281 cacttttaga gggaacaacc gctgtctctg gctgtttata gctatatgct gtttttttag
     8341 cgaatacagg tgttttttta ggcgtaggac gcatgccttc gatttccagt aactcctgat
     8401 cgatttcttc tacaaaacga gaaggtcggt tatattgcgt ccgtccatat aatgttctgg
     8461 agaaagcatt tgttaaatac aacgcttctt ctgctcgcgt gatccccaca tatgcgagac
     8521 ggcgttcttc ttccagttcg ctttcttcca tcaatgctcg agataaagga aaaaccccct
     8581 cttctagacc aatcaggaat acaactggga attctaatcc tttggctgca tgcaaagtca
     8641 tcaatgtcac ttgggaagca tcttcttcta aattgtcaat atcggaaaca agtgccagat
     8701 catttaagaa gaccgttagt ttttcttctg gtgcatcagc gtcttcttca ttttgctgtt
     8761 cgaattgttt gtcgaattct tgtgtgaccg ttaaaaattc ctccaagttt tcgatgcgtg
     8821 cttgtgcttc taatgtattt tggattttta agtcttctag atatccgcta cgatccaaaa
     8881 cctctttcgt caattctgtc actgtcaagt atgggatcat ctgagtgact tcttggatca
     8941 tctctccaaa tgcacctaat tgctgtcctg cttttccacc gatatttgcc agatccacat
     9001 tttgcgctgc ttcaagcagt ggccattcat gaagagaagc aaaactgcgt agtttttcga
     9061 tagatcctgg tccgatgcct cgtttgggcg aattaacgat acgctcaaaa ctgattgaat
     9121 cttgaggatt tgccagcaca ttcaaatacg ctaaaatatc tttgatttct ttacgatcgt
     9181 agaacttgtg ccctccaacc attttataag gaatatttgc tttcaacaga gtttcttcca
     9241 ttacacgaga ttgtgcgttc gtccggtaca agatggcaaa gtcgccgtaa ttccgatgat
     9301 tgcttcgaat ctcttcttgc atccgatcta cgataaaacg ggtttcgtct cgttcattat
     9361 ctgcacggta gtaagtgatc ttgtttcctt ctttgttttc tgtccacaag ttttttggtt
     9421 ttcgattgct attgttttca atgacttggt ttgctgcgct aaggatgttt ttcgtggagc
     9481 gatagttttg ttctagcaaa attactgcag catctggata atctttttca aaatccaaga
     9541 tgttctgcat atctgcaccg cgccagccgt aaatactttg atctgcatct cccacgacgc
     9601 acaggttcct aaatctacct gccaataaat tgactagcgt atactgtgcg tgatttgtat
     9661 cttggtactc atctacatga atataatgga atttgttttg ataatatgtg agtgaatcag
     9721 gatgttcttc aaataatcga atcgtattca tgatcaggtc gtcaaagtcc atacattgat
     9781 tatattgaag ctctttttgg taagcagcat aacattttgc cgcaatctct tcgtaataac
     9841 tgccttgcat ttttgcaaaa tcctgagggg tctgcaggct gttttttgct tgagagattg
     9901 ttcctaatat acttcgagga tcatattttt tcggatcaat gttcagttct tttagtatcc
     9961 gtttcatcaa ggtcagctgt tcagaagaat cgatgattgt aaagttccgg ttatacccga
    10021 taaaatcaac atctcttctt aaaatacgca cacacatcga gtgaaaagtc gatacccaga
    10081 catcttcgcc tccagatgcg agaatcgcat tgacacgttc tttcatttct tttgcagcct
    10141 tattggtaaa agtaatcgct aggatgttcc aaggattgac ttctttttcc tcaatcaaat
    10201 aggcaatgcg gtgtgtcagc actctcgtct ttccacttcc tgcacctgcc attagcagta
    10261 atggtccgtc agtgtgaaga acagcttctt tctgacgggg gttcatcccg tttaataatt
    10321 cagctttgga tgacattaac aacatccttt cttttatcaa tcttgttaat tatagcattt
    10381 tcttggcttt cattaaacta gctagttcaa aatcatttgt ttctttttat ggatttttcc
    10441 ttgtcaattc gttgatttcg cgctaaatta aaagaaagcg aggcgtttga atggaaaaaa
    10501 aaggaaaaat caagaaatta gataagactc agatatattt tattctaaaa ggaatatttg
    10561 ttggactgct gacaggaatc gtcgttagcc tgtttcgatt atctatcgaa aagctaagcg
    10621 atttagttcg aagtatctat gaaatgagtc gggaacagcc gatttactta attggcctag
    10681 ctatttgctg catccttgca gcatttttcg tgggttatct ggtcaaaaat gaaccggata
    10741 tcaagggaag cgggattcca caagtagagg gacagcttcg cggggaatta tcaatgaact
    10801 ggttctctgt tttatggaaa aagttcattg gcggtgtact ttcagttggt gcgggccttt
    10861 ttctaggtag agaaggacct tctatacagc ttggcgcatc cattggacaa ggagctggac
    10921 aattgtttcg gagtccatct tcagaagaaa agattttaat ttctagcggt gcaagtagcg
    10981 gacttgcagc agcattcaat gctcctatcg caggattact ctttgtttta gaagaaatcc
    11041 atcactcctt ttctccactt gtttggctga catcatttgc ttcagcaatc actgctaact
    11101 tcgtctctct ttactttttc ggcttgagac ctgttttata tctaggtgac cttccttctt
    11161 tgccgttgaa atattatggt tccttagtga tcttaggagt acttctaggc atcttaggtt
    11221 ttatttatca gaaggtcttg ctggctttgc caaaatttta caaccgattg cctttaccag
    11281 cttattttca cgggttcgtt cctttcttgc tgattttgcc aattggttat ttatggccta
    11341 gtactctagg cggaggcaat caaatcgttt tagcttttgg acatgcttcc ttgccaatca
    11401 ttatgattat cggtttgttt gttcttcgat tcgttttttc catgatttct tacggtggtg
    11461 gtcttccagg ggggattttc cttccgatat tgacattggg ggctttaatc ggtagctttt
    11521 atggaaacat tatggttgat ttcgggatgg atccaatcta catcaaggat tttgtcgtta
    11581 ttgccatggc tggttatttc acagcgattg gaaaagcacc gctgacagca attattttag
    11641 tgacagaaat ggttggctct cttaatcatc tgatgccttt aggattggct gctcttgttg
    11701 cttatatcgt caatgacctt ctcggcggta atccaattta cgaatcatta ttggaacgtc
    11761 tacttggaaa tactcagacc gcctcactaa aaggtgcaag gacaactttt gattttccag
    11821 taacggcaga gagttcttta gacggattaa tggtacgaga cttcaattgg cctaaaaata
    11881 tgctgctaat ctctatacgc agaggaaatc aggaaatctt gactcacggt gatacgatca
    11941 tgaatgtagg agatattttg gttatcttga ctgatgaagc aaacttgcca agaatcaagc
    12001 aggaaatcga ggctaaatct tctatcacaa atttgaagca atcattttaa cgaacatgga
    12061 aaaactattt tacaacaact attcatctac actacttgat tctatatgat tctataaaaa
    12121 aagaagagac tgggaaaaac cagcctcttc ttttttattt ctatgcttct gctgctgcag
    12181 gagcttttct caataaacca taaatcacac cagatacgac tgctccgata gcaataaaca
    12241 ccaaatacat gaccgggtga ctcagtaaga atacaacgaa aatcccgcca tgaggagcca
    12301 gtaatttgat cccgaaagct ccgactaatc cgccagttaa agcagaacca ataataaaac
    12361 ttggaatggc acgaatcggg tcagctgctg caaatggaat cgatccttcc gtgacaaacg
    12421 atagtcccat cacgatgttc gtcaaaccag catcttgatc tgttttgctg aatttattct
    12481 taaacaaacg tgtagcaacg aaaattgcca atggaggtac cattcctcca gccataacag
    12541 aagccatcac gacacttccg ccagttgcaa cagtcgtagc taaagttgct gtaccaaaca
    12601 cataagcggc tttgttgatt ggaccgccta aatctgccgc catcattcca gctaataatg
    12661 caccaagtaa agcagcattc gaaccactca tacttgtcaa gaaaccgttc aatgcatcat
    12721 tgattgcttt catagggaca ttgaccagca acatcaagaa accagtaatc agtaagccaa
    12781 acactggata aaagaggatc gttttaattc catccaatga ttttggtaag ttcttgaata
    12841 atttacgtaa aaatacgatg acataaccag ctaagaatcc accaatcagt gcacctaaga
    12901 atcctgcacc gcctgtatta gctaatgcac cagcagcaaa tccaacgatc aaaccagggc
    12961 ggtcaccgat acttgaagca ataaatcctg ctaataccgg cagcatgaaa ccaaatgcag
    13021 cttgtccgat ttggttgaac cagctagcag cttgattgta attccctaga tttgataatt
    13081 gatcatgtgg cacgccaata aattggtcga tcatgaaaga aagcgcaata gcgattcctc
    13141 caccaataac gaaaggtaac atgtgtgata cgccgttcat caaatctttg taaattcttt
    13201 gtccgatagt accatccgca tttccttctt ctgaactgct ttcttttcca tcaccatgga
    13261 atactggtgc agtaccacta agggctagat tgatcagctc ttctggttta cggataccat
    13321 cactgacagg acgattgatc agttcttttc cgtcaaagcg attcatctct acttttttgt
    13381 ctgctgcaac gattacacct tctgcacggg cgatgtcttc agcagtcaat cggtttttga
    13441 ttccttctga accgttcgtt tcgactttga tctccacacc catttctttc gcttttttct
    13501 tcagagcatc ttctgccatg taagtgtgag cgatccctgt tggacaagct gtaacggcaa
    13561 caacgaattt tctttctgga tgagcagaag cttctgcagc ttgtgtttct tgttctgctt
    13621 tttcttctgc ttctttttgc tcttcagctg tttggaacaa gtcttggact tcttctggtg
    13681 tatttgcttc ttttaatttt cctacgaaat ctgcatcaat cagcaatcga gatagtgctg
    13741 ctaatgcttg caaatgtgtg tcgtttgcgc cttctggagc tgcgatcatg aaaaacagat
    13801 aagttggctg tccgtctaag gcttcataat ctactccttt ttggcttttt gcgaataaaa
    13861 ctgttgcttc tttaactgca ctgtttttcg cgtgaggcat ggcgattcca tcaccaagac
    13921 ctgtagaagt ttgtgcttcg cgggctagaa ttccttcttt atatgtttcg atatcggaaa
    13981 tccggccggc atcaaacatt ttttggacca tttcatcgat tgcgcctttt ttatcagtcg
    14041 cttgcaaatc catgatcatc gcttctttga ccattaaatc cttgatattc atgattatcc
    14101 tccttgaaac taatcaattt ttgtgatttc aacttctggc agcaactcat caatcaattc
    14161 gcgagctgcc aagtcatcag aaaaagctgt tgcgcttccg caagcaactc cccatttaaa
    14221 ggcttcgatt ggatctttcg tacggctgta agccccaata aagccggcaa tcattgaatc
    14281 ccctgcacct actgaatttt tcaatgggcg aactaataca ttcgttttat aagttccttg
    14341 ttccgtgaag agcaaagcac cgtctccagc cattgagatc agcacattct gtgccccttc
    14401 agctagcaat tttttaccat acggaatgat ttcttctaca gattggaagg ttgtattgta
    14461 aagctcagct aattcgtgat tgtttggttt gatcaacaat ggtttcttaa caagtgcatt
    14521 ttttaggtca tcacctgttg tatcaatcac gaaatctgca cctttttctc gaatgatatc
    14581 aatcagttct tgataaaatc cttttcgcag gctagccggc gcgcttcctg acaatacgac
    14641 gatatctcct tgtcctactg ttcctaatgc ttgcttcaac tcatcgattt cttcatctga
    14701 aatagatggg cccaaaccgt taatttcagt ttcagtatct gattttagtt tgatattgat
    14761 tcttgtatct tcttttacgg ttgtgaacaa agactggatt tgttcttttt caagccactt
    14821 cgaaataaat tcgccagtga accctcctaa aaaccctagt gctgtagatt gagaatcgat
    14881 ccgtttcaaa atacgggaaa cattgatccc ttttcctcca ggtaacttga agtcttcctt
    14941 cattcggttc aaatcgccta gttttaaccc atctacgcgt acgatataat caattgatgg
    15001 attaagtgtt actgtgtaaa tcattgtatt gcctccttaa ttgttgtctt ttcacggaat
    15061 tcattaacga attctaatgg acaacgctcg gttatgatcg tggctgcttc caaaggtgca
    15121 acagaggtga aggacaactg gttgaatttg gtatgatcaa tcaatacaaa tgtctcttcg
    15181 gaatttttca tggctaaacg tttaacagct gcctcttctg ggtccggagt cgtgaatcct
    15241 tgttcaagat gggcaccgtt cattcccata aatgctttat taaaatgaaa attttttagt
    15301 tgttctatcg cattagatcc taaaacagca ttagttgcca gctttatcgt tccacctaaa
    15361 ataatggtag caagctccaa atcaactaaa tttgccgcat gttgaacgga atttgtcact
    15421 actgtgatct gttttccttg cagaaaagga atcatttcta acgtagtaga gccagcgtct
    15481 aaataaatga catcttcgtc attaatggtt tcagctgccg atttggcgat ttgctgtttt
    15541 tcgtgaacgt ttttgagtga tttttcactc atattctgct caaaattcaa taattgctct
    15601 ttcttagctc cgccatgaac tctttctaga aacccactat tctccagctc ttgtaaatca
    15661 cgtcttatcg ttgattcaga agcattaaaa aggtttacaa gatcttgtga tttcacgatt
    15721 ttctgctgtt caagcaagtc taggattttt tgtctacgtt cctctgtaag cattttcacg
    15781 atcacctcaa tacaaataat agcatatttt ttttctactc gcaatataaa tcagtcaaaa
    15841 acgttcataa aaattataaa tcagtcaaaa aaaaataaaa aaccagtcaa aaagactggt
    15901 tttttatttt tttgtctatc atcaagccgt tttatcgttt tttattttcg cttcttgttt
    15961 ttttcatata aacagaagca ggttttcttt ccttatgaag aagataataa taaagtccca
    16021 tcccgccaaa catgaccaaa aaaccgatga ctgatcgaat aggaaaatta ggaacaaaaa
    16081 agagacagac ggataataat gatgccggaa ccattattcg ataatagagt tgtttatcca
    16141 ttttcttcac ctcatatttt ttgtaaagta atcaattgtt ctaattctcg gtaatctaaa
    16201 aattgcacac gcagatgctg ctcacctttc ttgacatcga attggatact tcgccgcttt
    16261 ttctttattc gtttgaaggt aacatcagag agtctatgtt tgatttcctt taacggtaat
    16321 tctgacaggg attctgaagg aacatagatt cttaaggata aaagatactc ttgatatttt
    16381 tcatctgtta cctctacttc tagatattcc ctaatataat aacaataagc ttcgattcca
    16441 ttatccaaag caacagtcgg atcgataact ttatagcaca tcatgcgcga gcgattctcg
    16501 tcaacccaag gaaaatacgc ctgagcattt agtgttccgc gaacacgcct ttctttataa
    16561 tctccttgtt gaatatcata actttttgtt acaaaaaatg aagcattctt tttaggaaca
    16621 ggttgcattt gtgcattctg atactggaca gattggatcg tatggtcagt gtaaatgtat
    16681 tcaacgaatg gcggtttcaa taaaccgaca ccattgtccc aagcaagatg atcaaaccca
    16741 agctggtccc taaaatagga ttgaaacatt tgattgtttg gcttttgcca gttaaagggg
    16801 tctcgataaa gctggataca tatgacttcg ttttctaatt ccttcacttt ttctacttgt
    16861 tggatgtcga gaaaaatcgg tttagggatg atttgatgat aatagcgact ataatacatt
    16921 tcccaacacg aagtgaaaca taaaccttgg taaaaaagat cgtatcctgg aaattggttg
    16981 caatcgacta ctacttcccc gttttgttgt ttcattttag gtaaatgttc gatttcatcc
    17041 tttttctcaa acaatagccg ttgagagatc tgttttgtat tgtgatagat aaactcgcta
    17101 taagctcgca tataggcgaa caccccatga gcaatcattt ttttctgaat gaagtctcga
    17161 atcaaaaatt gcttttcttt gaaaacagag atagacaata cattttttat caataattga
    17221 ttatcttcca agcgaaaact acattcgttc tcgtcatttc ctacaactaa ccaactttcg
    17281 tctcttaccg atgctagcat tattttttct tgaagctttc gaagatcata cggatccgct
    17341 tgttgtgtga aagagcggat aaatgttggc tggatcaaca gacgtgtcaa aatagcccaa
    17401 tcgcttattt cctgtttttt ttcttcttca tttaagtctg tgagctggat agtcatcaat
    17461 aatttatctt cgccaatcat tttctcacct ctttaaaatc tttttataat ttaattataa
    17521 ccaacgataa agaaaaacta aaactttatg tcttagaaac caatttggac gattacatga
    17581 tagactaagt aaaaagaaac aaagaggtgt ttacaatggg gttgaaattt gaacgtacag
    17641 ataatttaga taaacttttc gaatcatttg ctgtcgatcc ggaaaaaaca gttgcaccaa
    17701 aagaagagat cgatcgattt ctaaaaccac agccacaaaa tgaaaagaaa aaagacaaga
    17761 aacaaaagta agttaagctc aaaaaaagac ttaccagcca aacttttatg aaagagtttg
    17821 actggtaagt cttttttatt ctttttatga ttcaattgct tgttcgattg ctgcccacgc
    17881 ttcttctttt ccctgttttg taacggaaga aaagagaata aacgtgtcat tgcgatcaaa
    17941 atccaacgct tttttgattt cgctctcatg cttgttccat ttaccacgag ggatcttatc
    18001 tgccttagtg gcaacaacaa ttacagggat atcataatac ttcaaaaatt gatacatctg
    18061 gatatcttct tgagaaggct tatgacgcaa atctactaaa gaaacgaccg cacgtagctg
    18121 gtctctagtc gttaaatatg tctcgatcat ctttccccat tttgctcgct cagttttgga
    18181 tacttttgca tacccatatc ccggaacatc gacaaaatgt aatgcgttct cgatcaaata
    18241 aaaattcaat gtctgggtct ttcctggctt accggaagta cgggctaaat tctttcgatc
    18301 aatcaatgtg ttgataaaag aagatttccc tacatttgat cgtcctgcca gagctatttc
    18361 tggcaattgt gtatctggat attgttttgg tgccactgca cttatgataa tttcagcttg
    18421 atggactttc atggtctctc tccttaacaa ggtgatgaat aaagcaagcg gctgtcgcaa
    18481 aagccaaaat gacttttacg gcagcctctt ttcatcaacc cgcttttttc tctgaatctt
    18541 tatagattac tgttggctca ccagacaatt cagctgcttc ttttgtgata atcacttttt
    18601 cgatgttttc atttgaaggg atatcaaaca tcacatccat catgatttct tcaatgatgg
    18661 aacgaagtcc tcgagcaccg gtattgcgtt cgattgcttt tttcgcaatg gctctcaacg
    18721 cttcaggttc gaattcaagt tcggtattat ctagagaaag aagtttttga tattgtttga
    18781 ctagcgcatt tttcggctca gtcaagatcc gtaccagatc atctgttgtc aatttctcta
    18841 aagctgccat aacaggtaat cgtccgataa actcagggat caatccgaat tttagtaaat
    18901 cttcaggaat gatatgctgc atgacacttt cgtcttcaga aagtttttgg ttttgtgtac
    18961 caaatccaat cgtcttttcg cccatacgat tcttcacaat cgtttcgatg ccatcaaatg
    19021 caccacctac gatgaacaat atgttcgtcg tatcaatctg aataaattct tgatgtggat
    19081 gtttacgtcc tccctgaggt ggcacgcttg caacagttcc ttctagaatt ttcagcaagg
    19141 cttgttggac accttcgccg gaaacgtcac gagtaataga tacattttcg cttttacgcg
    19201 caattttatc gatctcatca atatagatga tccctttttc tgcacgttcc acattgtaat
    19261 cagcagattg aagcaattta agcaaaatgt tttctacatc ttcccccaca taaccagctt
    19321 ctgtcaaact tgtcgcatct gcgattgcaa aaggtacatt caatgttttt gctaatgttt
    19381 gtgctaaaaa tgttttacca gaccctgtag gtccgatcaa gcagatattg cttttttgca
    19441 gttcaacatc atctgtgttt tcttgtgctt gctgattgac acgtttatag tgattgtata
    19501 cggcaacagc taacgagcgt tttgcgcgat cttgtccaat cacgtagtta ttcaatactt
    19561 caagaatttc tagtggttta gggacttcag tgaattcgcg tacagcttct tcataaaatt
    19621 cttcatcaat gatttcttta cataggtcga tacattcatt acagatgtag acccctggac
    19681 cagctacgat ctttttcact tcttcttggg ttttcccgca aaaagaacag cgtacggtct
    19741 cattgctact tggattgtca tacatggtct tcacccctta acttgcaaaa agtatgcaag
    19801 aaactatcaa agactttaca gtcttttact atcataacat agtttagtaa aaagaaaaag
    19861 tgtttaacaa aggatcaact gacctatacc tttgcatttt ttactcttaa caaaaaataa
    19921 ggaactgtga caaaatcgtg tcacagtccc ttatttcgaa taaacaattt tctagaagta
    19981 gcttcttcag aaatgattta ttacttgatt tctattcttt cgcttctgtc gctgtacctg
    20041 tgatcaattc gattgctttt ttcattgtca catcatgttc cagcatatct tctgtcaaca
    20101 cgcgtttgat ttgttcgatt ggcatgttgt atgtttctga taattcttgg atttctgcat
    20161 tgatttcttc ttctgttgct tgaagatttt cagcagctgc aattgcttcg atcacaagat
    20221 ttgttcttgt gcgcatttct gcttcacctt cgaattgttt atgcaagtct tcttctgtag
    20281 aaccagttaa ttgatagtac atttcaggag agataccttg acgttgcatg ttgttcaaga
    20341 attcgtccat tgaacgatgt acttcatcat gaaccatcac gtgtggcaat tcaacgattt
    20401 ctgcgttttc aacagccata cggatcgctg cttcatcttt tgcatcgtcc gctgcttttt
    20461 cttttgtttc tactaattct ttgcgatatt tttctttcaa ttcgtctaat gttgatactt
    20521 cgtcatcaac atcttttgcg aattcgtcat ctaattcagg cacttctttt gcttttactt
    20581 catggattgt cactttgaag actgcttctt ttccagcaag atcttctgct tgataatctt
    20641 ctgggaaagt tacatttaca tctagacttt cacctgattt atgaccaact aattgatctt
    20701 caaaacctgg aatgaatgag cctgaaccta attcaagtga gtaattttcg ccttttccgc
    20761 catcaaacgc ttcgccatct acaaagcctt cgaagtcgat tactactgta tcgccatttt
    20821 cagctgcagc atcttctttg ataactaatt cagcttgtgc ttcttgttca cgtttgatac
    20881 gtgcatccac gtcagcatct gttacttcac ggtcttgttt ttcaacaact agatctttat
    20941 attgtcctaa ttttacttct ggtttcactg ttacttcagc agtgattacc cagtcttgac
    21001 ctttttccat gctttcaaca tcgatttttg gttgagaaac aggatcgatg ccagcttctt
    21061 tgacagcagc ttcataagct tctggtaata cagcattcaa tgcatcttca tataaagctt
    21121 cttcaccgta catacggttg aatacttgac gagaaacttt ccctttacgg aatccaggta
    21181 cgttcaagct ttttttcact ttattaaacg cagttgttaa tcctttttgg atttcgtctt
    21241 gcgcaatcgt aaattttaaa acaccatcat tcgtgccttt tttttcaaat gttgcagtca
    21301 tttaattccc tccgagttta gaaattcatt ttatacatca aaaacgtttc atgcatacct
    21361 ttaaatagta cactaaccct ttcaaattgt aaacatattg aatggataga atccttgttt
    21421 ttcataacat ttttatcttt ttcactgata aaatctaatg gaagaagatc atttgctgca
    21481 aaattttttc tctttttttt aaaaaatctt gtttttcatc ttctgtacct tcatacatcg
    21541 tttttcctgt acacgcctct acagtcagtt gaaaccagcg cttcgggtct tcgatgtatg
    21601 tatcatagac aggataaaca attgcagatt gcaacgtgaa ttcttcattt aacacggaac
    21661 taagcagcgc atcttcatta ccgtaacgat ctgaaaatac acataattgc tggtaacttg
    21721 cctgctgctg cggctttggc agatcttttg gtatgacttt gactaacttt tcttcaatcg
    21781 tcaaatagaa aacaggatgg cattcgttca attgcctaag tgtctccagt aattttgccc
    21841 ttgctaaaat atggacctct ggcgatacaa taagtttact cgctgtttgg ataaactcat
    21901 gataaggaag ctgttcgatc tcatcaatag acgcaagctg acgtgcaggt tccaacgaag
    21961 gaagttcctc cgatttattg tggagtgcct tgatcttctg cctctccatt tgtccggata
    22021 attcttctgc aaattggatt ttttcaatga cccgctgctc gaaagcttca taaaaatctg
    22081 tacttgctat caattttcta gcatataaaa aatcttgtgt actgattaac aagtcaaaat
    22141 aaaattcagc aaactcctca ttttgaagat actgtttttc atgcaagagt gcttgcttca
    22201 atgcttcttt tttctcgtcc aactcgtaaa gacaaaaaac aagcaggcta ttagcctcaa
    22261 agctttcttt caactcgtaa gctcgttgaa ataattcttt tgcctgctga tattgctggt
    22321 ttgctagtgc ttgttgtgct actcgcatta aattctcata tttttctgga aaatcaatcg
    22381 gcttcacgca gtgtcctcct cttgctcatg ttcagctcat gttcaatagt agcaaaacaa
    22441 aaaaagcatg acaattaaaa ataactgaag caccctctaa aagctagatt ttagatctga
    22501 cttttagaag gtgctttcaa ctgttactgc tttttattgc tcatcagctg ttgacttcct
    22561 ggttgaatgc tttgatcaga ttgatcgtaa caacacttgt attagtgaaa aaatcgccta
    22621 gatgttgctt tttctgatta aagattgctg gaagataccc taacatcagc aaaggaaatt
    22681 ttagaatgaa ccggcaagca ccttctctaa ctaaaacggt tgaccagcta agttcttctt
    22741 catcaaagct gatgactcga ataccaaaga tcattttccc aatcgtttga ccatgattga
    22801 atttcgtcaa taaaataaaa tacgctagat aaataagtaa ggctgtgaat ccgtagatac
    22861 tcagataaga atctgaaaaa ttaagccaac ctagattttt ggcaatacca agtgttaaac
    22921 gcgtaatagc tccgatacac aaaagatcga ccaagaaagc aaacattcgg ataaaaaaac
    22981 ctgcatagaa atacttagga aaatcatttg cttttggcgg ttcatttctt gtgtccgtat
    23041 actttttcca tttacgttgt ttctttttga tttcttcggg cgtcaaaggc tctctttcaa
    23101 aagagctcag taccttttgg gaaaagttgg agtcaggtcc tacagcaggc tgctgttgct
    23161 tatctttttc ttgttcctta ttttcatttg aaagctctga catgcttact cacctccgta
    23221 ataatacatt gcttttggtg attccgctgt ccctagattc tcaagaacgg ataagatctg
    23281 actagtctca gaaggcttca atccctggaa ttctgctagt ttacttccta accatgtact
    23341 agcaaaccca gatggcgtgg aagaatattc tactagttcc gcatcttcaa gctgttgttc
    23401 ctttcgcata gcttttaaag catcttcagg aaatcccaat tcatcgacta aacctacttc
    23461 ttttgcttgg acaccatcat aaatccttcc atcagcaatt tttttgactt cttcttcaga
    23521 tttattccgt ccctcgctga cgattgctac aaaacgacta tatgcgctgt cgatatatgc
    23581 ttgaagcacc gcttcttctt cttttgtctc tggtcgcgtt cctgaaccca tatctttcaa
    23641 cgctccgctt ttaactgttg tatcttccac acccagtttt tctagaagtc ctgaataatt
    23701 caatcctgac atgatcacac caattgagcc ggtcactgtt tcttctgttg caaagatttt
    23761 atctgcttga gcagaaatat agtagccacc gctagctgcc atgtttttca tgctgacata
    23821 cattgggata tcatgttctt tacgaatcgt atccaatttc ttagcgattt ccgcactttc
    23881 gtagacaccg ccaccaggag aatttacttc taaaaagata cctttgactg ttggatcttc
    23941 ttcaatcgcc ttcagttgtt ccataaaatt tttatgattg taaccttcag aagcaaataa
    24001 acctgaagcc cctcccgcag caatcgttcc atctactgat aattttacga ttttttgcgt
    24061 actgtctccc tcttccaaca catttgaagc tagttcttca tccccatata accaactgtt
    24121 caatccctca atttgatcgt tttcctgagg cttagtcaaa ctagctgaaa ctaacgaaac
    24181 cacaaataat cctgcagcaa tcagaactgc tgcccaacgt ctcttattca ttctttctcc
    24241 tttctaatac aagtttttta tgacgatcac agtttctgac tgctcagaag tgtcgaaccg
    24301 ctctgctttt tcttcccgcg catacccgga aaacgactct tttgtcaatt catcttctac
    24361 cgtaaactca cgagcttcag caacttccaa ggcatcaggt gcgatttctt ggatgctatc
    24421 ccagccagta tctaaaaata ttttcgtatc atctgataca ccagctgatg cttcgaattt
    24481 ggacaattgt ttttttaaca ttcccagtgt catgatctca atttttgaat ccatttttac
    24541 tcctcctcta tccgattact ttctattgta ccgaactcct gaaaaagatg atagataaaa
    24601 acccattatt ttttgacata aaaagagcat ttgacaaagc atttgatata taccaattta
    24661 ttttttattc tttttttgtt gacaagaaca ttcgcaaaag gttatgattt taaatgtttc
    24721 cagataaaaa acaaaagagg aggatagtta taccttttag gatagcgcca ggtctgtgta
    24781 aacagatgac gaggagaggg tttatcgaaa gattcggcgg atggccctag ggactgcact
    24841 ctacagaaaa tccacaaaaa atatctgcaa agataaaaca aaaggatttt cctgcagctg
    24901 gaagcattca tacgaattca ttatagaaag taggatgttt tttatgtgcg gaattgttgg
    24961 aatgattgga ttaaaaaatg taacaccagg attgattgac ggtctagaaa aattagaata
    25021 ccgtggttat gattcagctg gtatctttgt ctcagatggc acaactgatt atctggtcaa
    25081 agcacaaggc agaattcaaa atttgaaaaa caaaataaat attgatacta caggaaatat
    25141 aggtattggt catacacgct gggcaactca cgggcaacct tctgaagaaa acgcccatcc
    25201 acatacttcc caaagtggac gcttcgtgct cgttcacaat ggcgtaatcg aaaactttga
    25261 agaacttaaa attgcttatt tagcaaatga ccactttatt ggtgagaccg atactgagat
    25321 tatcgctcat ctaattgaaa ctttcgcgaa ggatactaca acgcaagagg cgtttttaaa
    25381 agctttgcgg gtcatcaaag gttcttacgc tttcgctttg attgatcgga cagcacctga
    25441 tgttatttac gtcgctaaaa ataaaagtcc actattaatc ggactcggcg atggattcaa
    25501 tgtgattgcc agcgatgcaa tggctatgct tgctcatacg aaggaattcg ttgagattga
    25561 agatgaagag atggttaccg tcacatcaga aaaagttatt attcaaaatt ttgcaggtga
    25621 catcgtagaa cgttcttcat tcgaagcaca agtagattct tcagatatcg agaaaggtac
    25681 ctatcctttt tatatgctga aagaaatcga cgaacagcct attatcatgc gtcgtatcgc
    25741 tcaaaaatac gtaacagaag acaatcgtgt ctctcttgat caaaagctgg tcgatacatt
    25801 gtctgatagc gatcgaatct atatcgttgc ttgcggaact agttaccatg cggggttagc
    25861 aggtaaacag actctggaaa aattgacaca gatccctgtt gaggttcatt tagccagtga
    25921 atttggctat aacacacctc ttctttcaaa aaaaccattc tttattttct tgagtcaaag
    25981 tggcgaaaca gcagatagcc gccaagttct ggtaaaaatc aaccgtctcg gctacccttc
    26041 acttacgatt acaaatgttg ctggttctac tctttcgcgg gaagcatcct ttacactgct
    26101 attgcatgct ggacccgaaa tcgcagtagc atcaacgaaa gcttatactg cacaaatagc
    26161 tgtactaact ttattagcca aagctatcgg tgataaaaaa gaatttgaaa cttctcttgt
    26221 attcgatatc actcatgaat tgagtttagt tgctaatgcg atggaatcgg tcatcgccca
    26281 aaaagattat ttagaagagt tggcagaagt atatctcagc gatacaagaa atgcctttta
    26341 cattggacgt ggcgctgact acaacgtttc tcttgaagct gctttgaaat tgaaagaaat
    26401 cagttatatc caggcagaag gttttgccgc tggcgaattg aaacatggaa cgattgcttt
    26461 gatcgaagaa ggaacaccag tgattggaat catcagtgaa gaagtgactg gtgcgcatac
    26521 tcgaggaaac ctgaaagaag tcgaaagccg tggcgctaaa acactagtta ttgtctcaga
    26581 gggattagaa aaggaaagtg accagctggt gctaccaact gtccaccctt atctaactac
    26641 tctaaccaca gtcgtaccga ctcaattact tgcatattac gcaacgctat tacggggatt
    26701 cgacgttgac aaaccacgta atttagcgaa atcagtgaca gtagaataat aaaagaacaa
    26761 ggaccagtgt cagacatctg acactggtcc ttgttctttt attttttatg aaaatatctc
    26821 ttaatccagt ccgatttctt ctttgactac tgccgcgatt ttatcgacat agtaattaac
    26881 tttctcatca gtaggcgctt ctgccatcac tcgaagtaat ggttctgtac cggaaggacg
    26941 aactaggatt cttccttctg atcccatttc agcttctgcc tcttcaatca cttttttgat
    27001 tgccggaaca tccatcgcac cgtttttatc acttactcgg atattcacta atttttgcgg
    27061 atagattgtt acctctgctg caagctctga taatttctta cctgtctgtt tcatgatatt
    27121 cagtaactga attcctgaaa gcatcccatc tccagttgtg ttaaaatcta agaaaatcat
    27181 gtgcccagac tgctcgccgc caaagttata atcgtttttg cgcatttctt ctacaacgta
    27241 acgatcacca acttgtgtaa cgacatcttt caaaccgatt ccttccaccg ctttgtggaa
    27301 tcctaagtta ctcatgacag tcgtaacgat cgtatctttt ttcaatcgat ttttttctgc
    27361 caagtattta gcacagataa acatgatttt atcaccgtcg acaatgtttc caagttcatc
    27421 caccgcaata atacgatcgc catcgccatc gaaagctagt ccagcatctg ctcctttttc
    27481 aacgaccatc tcagctaaac gttctggatg ggtagagcct acgccatcat tgatatttaa
    27541 cccgtctgga tttgtgccca tggtataaaa atctgtttca agatcggcaa acaaacgatt
    27601 aacacttgtt gaagttgctc cgtttgctgc atcgacacaa atggtcaaac cggaaaggtc
    27661 accgttgatc gtttgtacaa ggaattgaga atatttcaat aagccttctg gaaattcttc
    27721 tacagttccc aatccttcag ctgatggacg aggcaattca tccacttcag catctaataa
    27781 tgcttcaatt tctagctctt ggtcatctac tagtttaaaa ccatctgcac cgaaaaattt
    27841 gattccatta tcttgtgctg gattatgaga agcagaaatc atgacccctg cgcttgcttt
    27901 ttgcaaacgt gtcagataag caacacctgg tgtagagatc acacctagct ggaacacttc
    27961 gatacccacc gataaaagtc ctgaaatcag cgcttcttct aacatttgac ctgagattct
    28021 tgtatcccgc cctactaaca cgcgtgggcg ttttccttct tcttcatgct ggcttaggac
    28081 ataacctccg caccgtccca gcttaaatgc aagttctggc gtaagttcct tgttggcttc
    28141 accgcgtacg ccgtctgttc caaaatattt acccatagtt gtaaaattac tcctttaact
    28201 taattttctg aggaatttgt tctgctcatt tgtgttgatt cgcttgtttc tgatgtttct
    28261 tctgtacttg tggtcgagct gcttgtccca gattccgaac tggaagaaat ggttgttgtc
    28321 gatggttccg ttcctgaatc agcagatgaa atacttctac tcgtacttgt attttcttgt
    28381 gtccgactgc tcgtcgaagc agagctactg cttgacgttt gcaacacggg tgtaatctcc
    28441 acactaactg attcgggctt gatacttaac ccctcttcta ctggtatttc aattttacga
    28501 gttgttcgat gattgatacc tgagacattg atcggtacag caatactgtc accgatcgat
    28561 gcaagcaaat cgctagagcc gcttacttct gcttccagtt ttgaaaaact gaaatcatag
    28621 ctttctaccc cggcagctgg tgttccttgc tgtatcccat aaagtcgtac cgacttgctt
    28681 ggcttgatcg aatcagctct cactgttact tgcactggat cagagacgat acttaatact
    28741 tcccctgctg cattcagcgc ctgtattggg acctcactat taatcccatc atctgtgacc
    28801 atcgaagcgt ccacatcagc tactactcgt ttgatttctg ccaatgtttt gtcacctgta
    28861 gtgatagaga cttttttagg actaacggaa gtatcatcaa gttcatatcc agatggtgtg
    28921 aacgttgaag gaatcaacgt ttccacatcg aaatctttta ttaccttttt ctcaaccgtt
    28981 actgtaatag tcgatggttc gatctttgct gtgacagcac tgctcaaatt ttgaattttt
    29041 agcggaacct catgtgttcc ttcgcccagc ttagtgatat ctgctgtgac gcggaacatc
    29101 cgtgtatctt cgtttgcctc tgcattcaac tgaactcggt ttgcactgga aagtttgaca
    29161 gtcactgcat tttcatatcc atggatatag tagcgctttg aatcataaga aatcttgatt
    29221 ggcaccccag taactgtttg attatacgct tcatttccag aaagcgtatt tggaacggac
    29281 tggccatttg cattgaagta cagcgcaata ctgaacagca atgcaataaa actgtaaaga
    29341 atgcttgtcc gtttctcttt tgagatcatt tgcgatcccc tcccttagtc ataccgtcta
    29401 ggaaagattg aatcacgttt ttcttgtttt ttgttttctc ttcagcaatc agttctctac
    29461 gcaaaattgc caaatattct tgctgggata agccagccat cagttcatta tctaatgtaa
    29521 tgctgacatc cccagtttct tcagagacaa cgatggtaat cgcgtcgctg acttcgctta
    29581 taccgacagc tgcccggtgt cgagtcccga attcttttgg aatcaacata ctttctgata
    29641 gaggaagata ggcgcttgct actgcgatct ttccttcttt tacaataact gcaccgtcat
    29701 gcagcggtgt attaggaata aagatattga tcagcagctc tccagtgata tctgcatcta
    29761 atgcaattcc tgtctcaata tactcatcta atccagtatg ccgttcgata gtaattagcg
    29821 caccgatttt tcgcttggac atatattgga tggctttgtc aaaagacaag atcatcttct
    29881 catcttcctg ctgttcgctt tttgattgtt tgaaaagcga actgcgtcca agatgttcca
    29941 gtcctctccg gatttccggc tgaaaaatca cgatagcagc tatcaccccg tacgtaatga
    30001 cttggttcat cagccaagac aaggtgtgca gaccaatgat ttccgctacg attcggataa
    30061 caataaaaat agctacacct ttcagaagct gaatcgcttt tgtgcctcgc agcagttgga
    30121 tcagtttgta tacaagatac cagacaacca gaatatcaag tatgttcacc aaaaaattca
    30181 gagagaacaa gtcaccggaa aacatttgct gccaatagtc caaattaaaa agttccccga
    30241 tttgaaatga cataaaaagc ctctcttctc ttttgagatt tcctctctag tatatcatat
    30301 gttttaattt tagaggctga tctgctcgta tttttcttga gaaaaacgca taattttcag
    30361 gaaaattgca agtatgcgtt ttatttttct ctgcaataaa tatttttaaa cttcagagaa
    30421 ttattcatta tattttttct gttatttttc ctttttttct tttgtagctt gttccatttt
    30481 tttacgtcgt tctgctctgg cagctcttct ttcttctgct tcaaggtccg tcgttttttc
    30541 ttttctagtc ttaacgggta catcgataga ttcctctggt tcaagtcgtt tcttgatttt
    30601 ttctaattct cccgtcagtg cagcatagtt gtaaaaacgt gttttagcgt cttggatagt
    30661 cttttcaaat aaagcttttg caagatttgg atttgcgttc tctagcgagg aaaagcgaac
    30721 ttgtttcctc atgaaatcag gcatagcaga gaaatcaggt tttttgtagt ccaaagtcat
    30781 tgggttcttg tttttttcga ccattgcagg gttatatcga tataatgacc aatagccaga
    30841 agaaacagct tcttttgctt ctttaagcga ttctttcatt ccaccaagca aaccatgtgt
    30901 gatacaaggc gtataggcaa tgattaaaga aggtccagga tacttttctg cttcttcaaa
    30961 agcctttatc gtctgcattt gattggcacc tgaagcaatt tgcgccacat aaacatttcc
    31021 atatgtcatc gccatcattc ctagatcttt ctttgaagca tactttccac tagccgaaaa
    31081 tttagcgatt gccgaagctg gtgttgcttt tgaggtttga ccgccagtat tggaatagac
    31141 ttcgttatcc aaaacaagaa tattcacgtc tgctccgctg gcaagtacat gatcgatccc
    31201 gccaaaacca atgtcgtaag cccatccgtc tccaccaatc atccattggc tgttttttac
    31261 gaatagatcc tttctcttgt atatatcctc cagttcaggg acaattgatc gttcgctttc
    31321 gatcgcagct tgcagttttg ctgctctttg ctgcgttcct tcgctctcaa acatgtgtac
    31381 caaccagtct tccatcaatt ctcgtagttc ttctgatact tttggcaata cttctttgat
    31441 tgaacttgcc aaagcctcgc gacgagtctg tgccgctaga agcataccat aaccaaattc
    31501 agcattatct tccaataaag aatttgacca tgcaggccct tgaccacatt cattggtcgt
    31561 ataaggagaa gcaggagaag caccgcccca aatagaagaa cagcctgtcg cattcgcgat
    31621 catcattcga tcaccgaaca tttgtgtcaa taattttaca taaggtgttt cgccacagcc
    31681 tgagcaagcg cccgagaatt caagaagcgg ttgattgaat tgtgtagaca agacagtatt
    31741 ctttcctttg actggatttg ctttttgtct taatgtcatt gcaaaagccc aattcacagc
    31801 ttgttctttc tgttcttcat aaggcttcat cactaaagct ttttcttttg cgggacaagc
    31861 ctctacacac agaccacaac ctgtacagtc ttccactgaa acttggatac ggtattttac
    31921 gccgtctgcg cctcgcattt ctctcacgat aaatccttct ggcgcttctt ccatttcctc
    31981 ttcatctgct aaaaatggac ggatggcagc atgaggacaa acaaaggcac attcattaca
    32041 catcgtacag cgatcactaa tccactcagg tacttctaaa gcgacgcccc gcttttccat
    32101 agaagccgtt cctaaaggca tttcgccagt tgtcattcca tttgctacaa gtgtaccaac
    32161 agagagttga tttccttcct gtgcattcac tggttcaagt atttcttgta tataaccagt
    32221 gttcctttta ttgatttttt caggcatctc caacgttctc caatggtctg ggatcgcgac
    32281 ttgatgaagc agttcggtcg tccgatcgat tgcttgtatg tttttttcta cgatagccat
    32341 tgatttatgt ccatagcttt tcagggcttc ttcttttagc agcggaagca cctcatcaaa
    32401 aggaatgatg tcagctaatt taaaaaaagc cgtttccatt gccgtattga tccggcgtcc
    32461 caaaccgact tcttgggcca atctcatggc attgatcgta tagaatctaa tgttattttc
    32521 agccaagtaa cgttttaatt ttaagggcag atgcgtttct aattgttcgt cgctccaaag
    32581 agtattcaat aaaaaaatgc cacctggctt caatcctttg accaagtcat agctatgcag
    32641 gtaagctggt gtgtgacagg caacaaggtc cgcatgctcg acaagatacg ctgaacgtat
    32701 cggcgtatct ccaaaacgaa gatgagagac agtcagaccg ccagattttt tcgaatcata
    32761 ataaaaatag ccttgcgcat atttatcggt gtgatctcca ataatcttga tagctgattt
    32821 atttgctcca actgttccgt cagatccaaa tccccaaaac ttggcctgga atgtttgcgg
    32881 ttctgtcaaa tccagacttt cctttggttc caaagattga taagtcacat catccacgat
    32941 ccctatggta aaccgttttt tgcgtatgct tgggtctttt ttcaattcat caaaaactgc
    33001 tgagatttgg tcgggagtca catctttaga ccccaatccg tagcgaccac caataacagc
    33061 cgggcgaagt tcagaatcat ataacgcact ttgaacgtct aataagagag gttctccacc
    33121 tgcccctggt tctttacttc gatcaagaac agcaattgtt tttactgtat gaggcaactt
    33181 ttgcacgaat gtttccactg gaaaaggacg ataaagatgg atattcaaaa aacctgtttt
    33241 ccgtccgttt gcattcaagt aatcaatcgt ttgttcaatc gtctgtgcaa ctgatcccat
    33301 agaaacaatg acttcttccg catcgtctgc tccgtaataa gtcaccaagt cataagaagt
    33361 tcctcgtaat cggttgatct ctttcatata tttttgaacg atttcaggta atttatcata
    33421 ataggggttg atcgtttccc gttgttgaaa atggatgtct ggattctggt tcgtaccact
    33481 aacagtcgga tgattgggat tcatccctcg tttacgaaat gaagctaatt tctcctgatt
    33541 gatcagagga gctaattctt catattccaa aacttcgatt ttttgaatct cgtgactcgt
    33601 acggaatcca tcaaagaaat tcaaaaaagg tacttctcct tcaatagaag caagatgggc
    33661 aacaggtgct aaatccatca cttcttgtac actgctttca gctaacatag caaatcctgt
    33721 ttgtcttgca gccatcacgt ctccgtgatc tccgaaaata ttcaacgcat ttgtcgtcac
    33781 tgcccgacta gcaacatgga aaacacttgg cagtagttcc ccagcaatct tgtacatatt
    33841 cggtatcatc aaaagcagcc cttgagaagc ggtatatgta gttgtcagtg caccagtttt
    33901 caatgatcca tggaccacac cagctgctcc tgcttcggat tgcatttcta ctacttttac
    33961 tggttgaccg aatacatttt cttttcctgc tgctgaccat tgatctacta attcagccat
    34021 ggtcgaactg ggtgttattg gatatattgc agcaatctcg gtaaatgcat aagaaatata
    34081 tgcggctgcc gtattgccat ccattgtttt catttttcgc atgattcatc atccttgttc
    34141 atattctctc ttattatctg ttccattata acgtaaaaca ttccattttt tcttttattt
    34201 ataaaaatat ttcacatatg tctatttgaa ttggtcatct aatttttaga caaacagtct
    34261 aaatcgttgc ctttttttgt cagacatgta taaactataa gcgaaagagg tgttttaaca
    34321 tggatatatc agtgattgat gcaacgaaaa caaatacaca aaaaggaatc ctttatggtt
    34381 catcgaatgc tcctaaaaaa atggtcgaat tcatcaacct atcttgtccg tattgccgac
    34441 aatggtttga agaatcttat gagctattag aagaagcagt ccaaagcggg caattgcagc
    34501 gagtgatcaa attgttcgat aaagaaaaag aaagcttgca gcgaggaaac gtgatgcacc
    34561 ggtatctcac aatcagcgat ggtcaaaaag cgatcaaaga gatcaaacaa atattcgata
    34621 ctcaagacga gtggaaacat ctttctctcc aagaagtagc ggattttgca gtagataaac
    34681 taaagctgac agaacaaaaa gacgaacagc tgagccaagc tgtcatcaac gaagctgagc
    34741 aagcacatat tcgatttgtt ccgactgtca tcttgggtaa agaaatcttt gatgaatcta
    34801 tttcaataga ggaattaaaa gaattgatcc aaacaaaata aaaaaataag gagcgtagga
    34861 caaaagtaaa gaacactttt gtctcacgct ctaaacacct ataaacggcg gaagcagaag
    34921 caactccttc ttatttcttg gagttaaacg cttctgtccc agcctcctta ttccgaataa
    34981 atggtgtcca aaagcttgca tctgccagat tatctcattt cttatgacaa gctgagcaaa
    35041 ttatctccac caaataattt attcatattt ttgacttgcg catactaact aattcttaaa
    35101 ttttcataca aaatttctca aattccctta acgagtaata tttatgtacg gtgattcaca
    35161 ctagtatccc aatcactttt taagttatcc cgatttcaat tctacttcaa aaatagttgc
    35221 ttttatgtat gctgttagtt gattagatgg tcgtttgttg agctaggtcg tttattttaa
    35281 acaagttgtt tctttagctt atacctatct cgtctaccaa acgcaagatg gcaaacacaa
    35341 atgcatacgc atctgtattt gccactttga ttcgtataaa gctaacaact cctaactcct
    35401 ctcatttaat agttgctctc ttttttattc agatacattt ttgctgatca cagcctagta
    35461 tttcaatggt tttgaacact aaaccaaatt gttccattac aacattcact ggctgatgaa
    35521 atggattaat agatttcgat tattcaaagc gattttctat tggtggattg tgttcccaac
    35581 taacaagacg gattccaaag tcattatata actcttcaag agttaaccct ttcctgttcc
    35641 caatagatgt atctctccca cgctcgatat aaaatatgga gtttcgaatg ccaagacctg
    35701 gcaaatcttt ccttgttaca gttacactgc tactaacttc cccatataaa atccagctcc
    35761 tccaaaatga taatatattt ttcgaccatc atctaactca tgtaacaata attgttgtgc
    35821 cctcttgtca ctcgccaaat gcaaacgcca cgtgcgatac catgccatgc tacctgcatc
    35881 tgcagaaaat ccatcaaata atgcaacaat tgtatcttct atcacaatcc tttccccatc
    35941 tacttcatat tctaatctaa aatcaaactc ccctcgggta atcgcaggtc ttggtggctt
    36001 aggacccaat attattctac ttaaaaccgc attcgttccc agatgaaaca cagctataac
    36061 aacaataatg attaatattt tgtttctatt tgataaattt ctcattattc gcaaatcacc
    36121 tctacattct cacatactag ttcgtaatac tcctttaata tcaaaatatc tactgatcgt
    36181 aataatattc gctatgaatt cctactactc gtataagaaa ggccaaatca tcagctttta
    36241 cttgctgatg atttggcttg tttctattta tcgtaattgt tttctaatca ccaaaattgt
    36301 taacaatcgg ttcagatatt tcccaattca ctagccttat attatattga tttaacaatt
    36361 cttcttcatt tattgtattt tgatcaagcg gaccaaattg ttctaataat tctttgtcat
    36421 gtaaaatatc ccttctagta atgcctcttt ccctttcaat gaaagaagca ctaggaaaag
    36481 tatgattata accattcaac ctatctccca tgtaataatt agcaggtcct ggaaaataaa
    36541 atatttgctt attatcacta acttctaaca gcaacactaa atcttctccg ctggctaaac
    36601 gacttgtcca tctacgatat ctccctatgc cttcgttcat tccaaatcca tcaaattcaa
    36661 ctattaacgt gtcttctatc acatgtaatt cttcattcaa ttcatactca agtctaaaag
    36721 gaaattctcc atatgtaatc tctggcaatg gtggtgctgg agttctccaa ataaatacaa
    36781 taactgtgaa tagaaaaaat ccaacgatcg atataaatgt tatgagacct gctcgaagta
    36841 aaacccgata taataaaaat gctgtatttc gctttgctat atctagaaaa ataaaaagta
    36901 ctgcaatcat aatgatagta aaagttgtaa aaaaacgcat ttttgccctc cctttataaa
    36961 catcgattct caaattctaa accaaatctt ggtagttcaa gttcaggtat aacgtattcc
    37021 aaccatacat ctcaattact atttatgaac ttatgattat cactgaataa atcactccat
    37081 ccccttgtta aaacttctac attaattaca cctggttgtt ttcgactagc taatccaatg
    37141 aacttatcaa ccatccttat ccaccaacca cgagaatctt gaccagaagt aagaagagca
    37201 gttctcaagg atgatcgagc agttccttcc agttttttaa ttaatcaggc cagttataga
    37261 taaatacttg atcttatcta tatcaggact tctatattaa gcaaaaattt atgtacaaaa
    37321 ctaaaatctt cattcagttg tctccccgct ttttatacga ttgtattaaa aacaatagaa
    37381 gcctttccaa attatgttac tccagtaaag atggaattat agtttgacgg aagaaaagca
    37441 agtataactt ttaaaaaaaa ctgatacatt cgcatctcct gcttcatgta tcagtttttt
    37501 ctttggatta aactgcttct tcacgcagtt tttccgcaaa ttcatttatt ttgcgaattc
    37561 ggtgattaat tcccgatttt gatatcgcac ctgagggaat catttcccct aattctttca
    37621 agctgacctc tggatgttga agccgaagtt ctgcgatttc ctgaagtttt tcaggaaggg
    37681 catgtagacc gacctttgct tcgatcaatt cgatgttttc gatttgttta gaagccgcat
    37741 caatcgtctt gttcagattt gctgtctcac aattgactag acgattgacc gaatttctca
    37801 tatcccgtac gattcgaaca tcttcaaatc ggagcattga gttggttgca ccaatcaatg
    37861 ttaagaaatc agcaattttt tctgctcctt ttaaataaga aatatagcca ttgcgccgtt
    37921 caagcgttcg agcatgtaga ccgtaataat ttaacatatc gcaaatgtct tggttatgct
    37981 gttcataaat agaaaatatt tccaaatgat aacggctcgt ttccggatta ttgactgaac
    38041 ctgaggccat aaaagcacca cgtaagtaag aacgcatttt ttgcgaattt cccataatct
    38101 cgtccgaaac gtgtccattg aacatcatac catccatgat atcaagatcc atcaacacat
    38161 cttttgtgcc ttgcttcaac cggacgatat agacattgtt cttttttaat ttcatttttt
    38221 tacgaacgag tagctcactt cgtacctgat aatgatcttt caaaagagaa tagatacgtc
    38281 tggcaattgc agcattttct gtttggacgt tcaaaataaa ctgctggttc acaataccta
    38341 aagagccgtt cattcgcagc aaagcagcta attccgcttt cgcatgttct cgatgaactt
    38401 ccaaaccagt tagttctttc ttcacatctg cagcaaatga catcctattc tcctcctttc
    38461 tccaacaata aattgcttaa tattttgaac cgaaaactaa acggaacaat tcttctacta
    38521 ctttgtctcc atcgtggaag acaccaccat ctttcaattc caaaaagtcg gtggaaatca
    38581 ctcgacatcc ttcatttctc aatccgttga agtcgtgtgc gacttgtact agatactcat
    38641 catagatctc tgggtccata taatcttcag gcactttttc cgtattgacc aatactgtat
    38701 cgataaaagg ctgattcaaa tgcttgtgta aaacacgtat atgatcggca tctgtgaaat
    38761 gttccgtttc ccctttttgg gtcatgatat tacagatata gacggtttca gcagttgtct
    38821 tgagcattgc ttcgccgatt tctggtatca ctaaatttgg aaggatactg gtgaataaac
    38881 ttccgggtcc caaaacgacc atgtcggcgt ccataattgc tgaaacgact tttcgagccg
    38941 ctttggcttc acttttatca tttgtgttgc agacatacac acggtcaatg gttttacggt
    39001 cgatcgcgat tttagattct cctactgcag tcgttccgtc tttaaagaca gcatgcaagg
    39061 tcaaaggagt ttctgaagaa ggataaacat gtccatctac atgcatcatt tttgctaata
    39121 attgaatcgc ctcataagtg cttccccgca tctcggaaac tgcggcaatg atcagattac
    39181 cgatcgtatg attggctaaa aactgatctt cctttttgaa acggtattgg aaaatatctt
    39241 catagaattg tggcatatcc gataacgcca ctaagacatt tctcaagtca ccaggaggag
    39301 ccatagcgat cgattctctg attgcaccgc tgcttccccc atcatctgca acagtcacta
    39361 ctgctgtgat atctgctcct tgatttcgca aacttttcag gataactggc agaccagtgc
    39421 caccgccgac cactacgatc tttggttttc ttatccggta ggttttcatt ttcacgaccg
    39481 gttcaccgtc tctttccttt tatccttgtc ccgatgtgtc acattgactt tatagttttt
    39541 ccctaaagca tttgccaaac gttcagtcaa tgccacagaa cggtgttgac cgcctgtaca
    39601 gccgattgca actgtcaagc tgctttttcc ttctttaatg tatccaggca atacagtttc
    39661 cagaagatcc aaaaatttat ggtagaatga ttgcgtttca tcaaaggaca tcacataatc
    39721 atagactggc tgatcttttc cggtcaatgg tcttagttcc gggatataat gagggttggg
    39781 caaaaaacgc acatccatca caatatccga atcgatcggc aacccgtatt taaaaccaaa
    39841 tgatacaaat tcgatccgaa atccttggtc tccctttgat ttgaatgact cattgatttt
    39901 ttcacgtaat tgtcgtggtg tcaatgtcgt cgtatcaatg atcacggaag cttgggcttt
    39961 caagtcgtct agtatcgccc gttctttacg tatcccttca gtgatcaaac cgtccatcgc
    40021 cattggatgt gctcgtcttg tttctttgta gcgagccact agttcttcgt ctgaagcatc
    40081 taaaaataag atagaagtgt cgatgaagtt cgtattttcg atttcgatca gcatgttttg
    40141 gatttcttca aagaaggaac gagaacgtaa atccactcct aaagccattt ttgtgacttt
    40201 gcctgattct ttgattaatt cccagaattt tggaatcaat cgaggcggca tattatcgat
    40261 acaaaaatag cccatatctt caaaactttg gatagctact gttttccctg caccgctcat
    40321 acctgttatg atgactaatt gcaaattatc tgtcataatt acgaactcct ctcacattgt
    40381 gcatagtaaa attatatcat tccgggcgta tcattaccag ttttcttttt cttttacaaa
    40441 aagatttgga ccaaatatct tttaggatat ttgccccaaa tccaattttt ttacttttcc
    40501 gatgctgtat ccaatgcctt gcttctttca gctagcgctc gttcaatcgt ccgatctgct
    40561 aaaatagatt gggcatcgat cactggataa tggttatctt cagcaaattc atgcatcaat
    40621 gacaattctg tgcaacctaa gataactttt tcacagttta ggcgctctac cgcttcttct
    40681 aagatttcgt aatatagctc ttgattcaaa taatccgatt ccttgatctc atgatagatc
    40741 agataattga ttttttcttg aagaacagta tcaggaatca ctgtttcgaa tccaagattt
    40801 ttgacttcgc gttcatagat tccagctttc atacttcctt ctgttcctag aatcgctact
    40861 ctccctgtcg tatgctgacg gacaagttca tttgctgctt ctcttggcat atgaaggata
    40921 ggaatatccg ttgccgcttg taattcttca aaaaagtagt gtgcggtgtt acaagtcaac
    40981 acaatgaagt tcggctgcaa taaattttgt ttctcaatat catccagcag aaacggcatt
    41041 ggattttctt ctgatcgatc taaaatataa gctgtacgat caggaactgt tgcatgattg
    41101 aataagacat aattcaaata ttcttgatct tttgtagctt tcgttcggtg gttgatcaag
    41161 cgaacaaaac tttctgtcgc catcgtgccc attccgccta aaatactgaa aaaattctcc
    41221 atgaactagc cttctttcac atgaaaatac tttttgaatc ttggaatata gttatggaac
    41281 atatatttca tcaacaacca gcgcttgatt gaccggtctt tttcataaaa cacagtagta
    41341 ccgtaacgat tttctttgat catttgctca gctagttttt tgtcttcatt ttcccgagca
    41401 tattctaaaa agattttttt gggcacaccc atccataatc ttgctttatc tgattgattc
    41461 gttccatagg tcgtttcaac aaagggtttg ttaaacactc gatcttctgt gacgaaacga
    41521 gccagattca agccgttcaa tgtcacaaag aaactgctac gaccttgtct caaattgatt
    41581 tcaaataatt tatattctcc atctctagga tcatacttca tatcgaaatt ggcaaagcct
    41641 gtatattcga ttttttccaa aaatgcctta atggtttgat agattttttc gttataatct
    41701 ggcatgatca caacgtaatt accaatcgat gctggtgtag gatcttctaa cagtggatga
    41761 ccaagacaca tcatccgaac ttgatgatct tcatctacat acgcatttag cacacgcata
    41821 ttactatcat cacccgggat aaaatcttgt acaatcattt cacttttata accggcttcg
    41881 tatatccggc ctaaaattaa atcgaactct tctctagtct ctaaaataaa agcttttttt
    41941 cttccttcaa attggacaga aagatactcc acactgtttg caggtttcaa agcaactggg
    42001 aattcaaaag gcaattcctg ttccaaatgt ccatttacta acatttcttc tctgacgatc
    42061 aatgttttag gatacggaag atcatattct tcacaaactt cataaaagct tactttattg
    42121 atcagtcttt caaataaaga ataatcaata tatggacaga taaaatattc tgacagctct
    42181 tgtttatgtt gggagatcaa ttctgcatat ccatcaccac aagcaatcaa aagatatttt
    42241 ttactcttat cagaatatct ttcttttgcc aaacgaagca tcgtctcgat aaacacaggg
    42301 tctttatcaa atcctggaat aacttctaca ttgacaattt tactgtagcg ggtaggggct
    42361 aactgatccg aagcatatgc ttggcagatt ttgccgtatg cttcattaaa agaacgtgcc
    42421 ataccataaa cgttcatgtc gcttcctaat aatataggga taaattcttc attttcaata
    42481 ctgttcatca ttatctctca cttactcata atctcttgtt tttcttttcc aactacacaa
    42541 ggaatatcat accataaaga aaaaagcaat caaaggaaac tcctccgatt gctcaattct
    42601 tttttgaacg gattgaactt ataggaagtt tttgtctata ccaatcagtg tagaaagaac
    42661 taccatgtaa tgattctaga acactgatat taataaaaca agcaaaaatt cattttttta
    42721 tgttttttta actatctcag ctatctatcc tctttatacc attatttttt tcaaatagtg
    42781 acctgtataa ctttctttta cgttaatgat ttcttctggt gttccagtcg caaggatcgt
    42841 tcctccacct tctccacctt ctggtcctaa atcaatgata taatctgctg ttttgattac
    42901 atctagattg tgttcaatca ctaaaactgt gttaccagca tctactaatc tttgtaatac
    42961 atgcaacaag cgggcgatgt catcgctatg aagtcctgtc gttggttcat ctagtatata
    43021 gaaattcttt ccattagaga ttttgtgcaa ttcactggca agtttcatcc gttgtgcctc
    43081 accaccggac aatgtcgttg ctggttgccc catcgtcaca taacctaagc caacatcaac
    43141 aatcgtttgc agtttgcgat gaatctttgg aatgtgcttg aagaattcta cagcatcttc
    43201 tactgtcatt tccaaaatat cagcaatgct ttttcctttg taatgcactt ctaatgtttc
    43261 agagttatat cgtttgccat gacatacttc acaaggaaca tagacatcag gcaaaaagtg
    43321 catttcgatc ttaataattc catccccgcg acaagcttca caacgaccgc cttttacgtt
    43381 gaaactaaaa cgccctttct tataaccccg catttttgcc tcgttcgttt gagcaaataa
    43441 cccacggata tcatcaaata cacttgtata agtcgctgga ttacttctcg gcgtccggcc
    43501 gattgggctt tgatcgatat cgatgatctt ttcgatactt tcgtagccgg aaattgtctt
    43561 gaatttacct ggcttagcag aattcttatt taatttttgc gctaacgatt tctttaagat
    43621 actattgacc aatgtactct ttccagaacc agacacacct gtgactgcta caaattctcc
    43681 taatggaaat tcaacactaa tatttttcag attgttttct gaagcaccag tgatcttgat
    43741 tgctttccca ttacctttac ggcgttcttt tggtacaggg attgattttt tccctgaaag
    43801 atatttccct gtcaaagaat tttcatcatt agctacttct tcaggagtgc ctgcagccac
    43861 gatttgtccg ccttgttctc cggccccagg tccgacgtca atcagataat ctgctgccca
    43921 catcgtatct tcatcatgtt cgactacaac gagggtgttg ccaagatcac gcattttctt
    43981 taatgagcca atcagtcgat cgttgtcgcg ttgatgcaat ccgatcgatg gttcatctaa
    44041 aatatacaaa actccagaaa gattcgatcc aatttgtgta gccaatctga ttcgctgcgc
    44101 ttctccccca gataatgttc cggaagcgcg actcaaagtt agatagtcta gtcccacatt
    44161 ttccaagaat gaaagtctgt catttacttc ttttaaaatc ggtttggcaa ttactttctc
    44221 ttgttcagat aacgttaagt ttgagaagaa atctactgct ttttgaatag acaactcatt
    44281 tgtttgcccg atattcgttc cattgatttg aacagataga gcttggggat tcaatcgata
    44341 acctttacat gtctgacaag ttaattctgt catataaaga cgcatttgct cacgcgtgaa
    44401 atcactgttc gtatcatgat aacgacgctc gatattcttc aatacccctt cgaaagtcgt
    44461 ttctacatcg cgaacgccac caaaatcatt ttcataatgg aaatggaaaa gatcatctgt
    44521 cccattcaag atgatatcct gatgctcttc cggtaattct tcgaatggtg tatctaaatc
    44581 gataccgaaa ctttcacaag cctgcgctaa catttgagga taatactgag agctgattgg
    44641 attccatgga acgatagcac cttgactaag tgtcttcgtt ctatctggaa tcactaaatc
    44701 ttgatcgact tctaatttga cacctaaacc atcacagtct ggacaagctc caaaaggcgc
    44761 attgaatgag aacagtcttg gttctagttc gccaacagta aatccgcaat aaggacaggc
    44821 atagtgttcg ctaaacaaca tttcttcttc accgatcacg tcaaccagag catagccgtc
    44881 tgccaatcgc agagccgcct ctaaagaatc aaatagacga gaacgaatcc cttctttcac
    44941 aatgatccgg tcgatgacga tcgcgatatc atgttttttg tttttctcca gctcaggcac
    45001 ttcacttaaa tcatagatct caccatcgac tcgaacgcgg acgtatccct ctttttggat
    45061 tcgttcgaat atttttttat gttgtccttt tttctttacc acgatcggtg ccaacacttg
    45121 gatctttgtg cgctcaggca aagccattac ttgatctgcc atttgatcta ctgattgact
    45181 ggtaatctcg atatgatcgt tgggacaaat cggatgtcct acacgtgcaa acaacaagcg
    45241 taaatagtca ttgatttccg tcacagtacc tactgtcgac cgaggatttt tacttgttgt
    45301 tttctgatca atagaaatcg ccggactcaa tccgtcgatg ctatctacgt ccggcttatc
    45361 catttgtcct aaaaactgac gagcataagc agaaaggctc tctacgtatc tccgctgccc
    45421 ttcagcgtac agcgtatcaa atgctaggga actttttcca gaaccggaca aacctgtaac
    45481 gaccacgaat ttatctcgtg gaatcgttac atctatattt ttcaagttat gggcacgtgc
    45541 accgtgaatc gtaattttat cgttagccat gttgtcctcc tactttgaag cttttaattc
    45601 taaaatcata tctcgcacat tagcggctgt ttcaaaatcc aatgctttcg ccgcattttt
    45661 catttctttt tctaatttca tcaataacgt atctttttct tctttcgtca tttcttcata
    45721 cgagacttgt accgcttctt ttgtatcatc ttccgattct ttcgtaatag aaatcaaatc
    45781 tcggatttct ttaatgatcg tttttggaac gatcccatgt tcttcattgt acttctgctg
    45841 aatcgtacga cgtcttgacg tttcatccat cgctagacgc atagaatctg ttactttgtc
    45901 tgcgtacatg attactttac cttcttcatt ccgagcagct cgtccaatcg tttggactaa
    45961 ggaacgttca ctacgtaaaa agccttcttt atccgcatcc aagatagcaa caagggaaac
    46021 ttcaggtacg tctaatcctt cacgaagcaa attgattcca actaacacat caaattcacc
    46081 taatcgaaga tctcgaatga tttctgttcg ttccagcgtt ttgatatcac tatgcaaata
    46141 tttgactttg atccctaatt ctttgaaata atctgtgagg tcttctgcca tttttttcgt
    46201 caatgtcgtt acaaacaccc gctggtcttt ttcgactcgt tcatttattt cgcctactag
    46261 atcatcgatt tgtcccatga ttggacgaac ttcgatcact gggtcaagca gccctgtcgg
    46321 acggatgatt tgttggataa cggtatctgt ttgttcatgt tcatatggtc ctggcgtcgc
    46381 agagacataa atgatctgat tgacatgttt ttcaaactct tctaaccgaa gtggccgatt
    46441 gtctaaagca gatggcaaac ggaaaccgta atctactagc atctgttttc tcgctcggtc
    46501 accattatac attcctctga tttgaggcat ggttacgtgc gattcgtccg ccacgatcaa
    46561 aaaatcttca ggaaagaaat ccaatagcgt ataaggcggt tcaccttctt tacgtccgtc
    46621 catatgccga gaataatttt caattcccga cgtgtagccc atttctaaca tcatttcaat
    46681 atcgtaattg gttcgctgtt ctaaacgttg agcttccaga agtttgtttt catttcgcaa
    46741 gacagttaaa cgctgttcta attccgcttt gatattcgct acggcatgct ccatatgttc
    46801 atcattcgtc acaaagtgag tcgccgggaa gattgctacg tgttccgttt ctcctaaaac
    46861 ttcacctgtc agtgcattga cttctcggat acgttcgacc tcatctccaa aaaactccac
    46921 acgtaaggca cgttcatctc ttgaagccgg aaaaatctcc acgacatcac cgcgcactcg
    46981 aaaacgaccg cgctgaaaat ctatatcatt tctttcgaat tggatactga ctaagtcacg
    47041 aatcaactga ttgcgatcta gttctgctcc ctgtcgaatc gaaactactt gtttttggta
    47101 ctcaaaaggc gagcctaatc caaaaataca tgaaacggat gcaatgacga tcacatcatt
    47161 tctttctaat aatgaactag tagccgaatg tcgtaatttg tcgatctcat catttacact
    47221 tgaatctttt tcgatatacg tatcgcttga aggcacataa gcttcaggct gataataatc
    47281 ataataagaa acaaaatatt caacagcatt gttagggaaa aattccttga attccccgta
    47341 cagctgacca gccaatgttt tgttatgggc aataatcagt gttggtttat tcactttctc
    47401 aataagattg gaaatcgtat atgttttccc tgttccagtc gcacctaata agatttgtgc
    47461 ttttttcccg ccgactacgc catccactaa ttggttaatc gcttcaggct gatcaccagc
    47521 cggttggtat ttcgagacaa gctcaaagtg tcgggaggta tctctctcaa tcattcttcg
    47581 tcctcctttt cattcattcc ttttcatttt acgaccaata aaaagaaaag gaaagcaaag
    47641 gcattcctta ctaaaaaatt ataccacacc gaacatactt tcgccacttt tttatcttat
    47701 tatacatgtt atgttttata acataaaatg ttagaaactc gcattttttt cattttttcg
    47761 agcttacagt cttgtctgat tcagcacttt tcgcctataa taataaaata ttggaaattt
    47821 aggaggttga ttatgaaaag aaagcattta tttcactcat ttgttttctt aatgacagga
    47881 cttgtgacac ttgcgtttgg tcatgttgca caagctgaca acactacaac ggcagagtca
    47941 agcacaagcg agacaatgca aaaaatagag cccaaaaaag acgtatacgt aattgccagt
    48001 gactctgctt ttgctccatt tgaatttcaa aacgcaaagg gcgagtacga aggcatcgat
    48061 gtaaaattga tggaaaacat cgccaaactg caaggattta acatccgaat ggactaccgt
    48121 ggtttctctg ctgctttgca agctttggaa tcaggacaag cagacggaat gattgccgga
    48181 atgactgtaa cagatgaacg aaagaaaagc tatgattttt ctgattctta ctttgatagc
    48241 gggatccaat tagctgtcaa aaaaggagat acttcgatca agtcttatga agatttgaaa
    48301 ggaaaaacag tcggagcaaa agttggtacc gaaagtgctg aatttttaag cgaccatgaa
    48361 tctgaatatg gctattctat caaatatttt gatgctgctg atcaattgta cgacgggtta
    48421 aaagttggcg caatcgatgc aatgatggat gattatccgg taatcggtta tgcgatcaaa
    48481 caaggacaag aattggaaac accgatcaaa aaagaatctg gcggaaaata tgcatttgcc
    48541 gttaaaaaag gacaaaatcc tgagcttctt aatatgttca atgaaggatt gaaagaatta
    48601 aaaagaacag gcgaatacga taagattatt aaagaatatg tagcggatgg ttcagaaact
    48661 tccagtgagt cttccactgc tgatgaatca acatttcttg gacttatcca aaacaactat
    48721 caagcattgt tgaaaggact ttggagaaca attctcctaa ctttgatctc ctttgctttg
    48781 gctatagtaa tcggtgtgat ttttggatta ttcagtgtag caccaatacg cgctcttcgc
    48841 acaattgcta gtatttatgt cgatatcatc cgaggaattc caatgatggt tcttgcgttc
    48901 tttattttct ttgggttgcc tggtatcgtt ggatttacga ttcctgactt ccttgctggt
    48961 gttatcacct tgactcttaa cgcaagtgct tatatcgcag agattgttcg aggcgggatc
    49021 aacgccgttc ctgtcggaca aatggaagct tccagaagtt taggtctttc ttataatcgg
    49081 acaatgcaaa aaatcatttt gccgcaagcg atacgcatca tgatcccatc attcgtcaat
    49141 cagttcgtta tctcattaaa agacacaacg atcatttccg caatcggtgt agtcgaattg
    49201 ctgcaaactg gtaagatcat tgttgcacgt acaacacaaa gtacgtatgt ttacttgatc
    49261 attgcgatca tgtacttgat tttgatcaca gcattgacaa aattagcaaa agttttagaa
    49321 aagaaggtga agtaagatgg cagaaaaaat cttagttgag catttagtca aaaaatacgg
    49381 cgataacaca gtattaaacg acatcaatgt atccatcaac gaaggagatg tcgtctgtat
    49441 cattggccct tcaggttcag gaaaaagtac attcttgcgt tgcttgaatc gtttagaaga
    49501 accttctgac ggtgaaatta ttattgacgg cgcccacttg atggataaaa gcacagatat
    49561 caacttggtg agacaacata tcggaatggt attccaacac tttaacctat tccctcatct
    49621 ttctattttg gaaaacatca ttttagcacc gatggacctg aagaaagaat ctagagaaga
    49681 agcagagaaa aaagcaatca aattactgca gacagttggt ctagaagata aaaaagatat
    49741 gtatcctgaa atgctttctg gtggacaaaa acagcgtgtg gctattgctc gtgctctagc
    49801 gatgaaccct gacatcatgc tttttgatga gcctacttct gcactcgatc ctgaaatggt
    49861 cggtgatgtc ttgaacgtca tgaaaaagtt agcagaacaa ggtatgacga tggttatcgt
    49921 tacgcacgaa atggggttcg ctaaagaagt ggccaatcgc gtcatgttca ttgacgacgg
    49981 aaacttttta gaagatggaa cgcctcaaca aatctttgaa aatccgcaaa atgaacggac
    50041 aaaagatttc ttgaataaag tattaaatat ttaataaaaa ccaaaaatgc acggtcgcca
    50101 tgaagggacc gtgtattttt atcttcttat tttctcacct aatcgtatca gccgcatcgc
    50161 ttgttttcct gcacaaacaa gcaatcgctc tacctgttcc atcgcataag aaagtaccat
    50221 cggttcattg atgatatcaa gtacatagtc gataccaccc tcacttaatt gagcttgatt
    50281 tttcttctcc atattatgta gttgtgggac aactttctga caatcagcaa ttgtgtcaag
    50341 aacggatcaa tcctttattg gagttgctcg aaagggtctt ctcttattac ggacaggctt
    50401 tgctcactgt acatagacaa caaatcatta tcctagtcaa tcggatttcc agagcctcat
    50461 tgctatcatt gcttgataaa atccagacaa agtttaataa aatgtatcag ttacagctaa
    50521 actttggaat tgggtcgctt tgttatacag agcaagagac accgcaatct ttccttcatg
    50581 ccaaacaagt ttgcgaatgg atagctttcc atcaatctgt gaacgagatc cgcttttttg
    50641 aagatttaga cctcgggatc gttttaccag caatcccgtc agatcaacga acattatatg
    50701 taaaacgtat tttgaaaagc ctgacagaag aagaagtaca tttgttcaag aagactttgg
    50761 catgcttcag taaaaataac ggaagcatca aaaattgctc agaagaatta tttattcata
    50821 aaaacacctt gcaatatcga ttgaacaagt tccattctct cactggttat acccctagaa
    50881 actatgacga ttatcatatt ctaaagctgg cttttttgtt ggtacaaaca tgacaactac
    50941 aaaaaaacca ggcgaacata tgattgttcg tctggttttt aattattaat gacttagcgt
    51001 ttttactaga aaaactactt ccgctttttc ccgccaaaag catctttaaa cttatcgaag
    51061 aaaccgtctt cttgctgttc ttcaactttg atgccgccag cttcagcgaa tgcacgtaat
    51121 gcttctcttt gttgttcatt tagatttttc ggtgtgatca gttttacttt gacatgttgg
    51181 tcgcctgttg caccaccacg taacttcgga gcgccttttc cacgtaaacg gaagttcgta
    51241 cctgtctgtg ttccagcagg gatcttcaat ttcacatctc catggacagt tggtacttgg
    51301 acttcatccc ccaaagctgc ttgtacaaaa cttaaaggca attcatagta aatttcagaa
    51361 ccttcacgat caaagatatc actttcttct acacggaaga ccacatacaa atcaccaaat
    51421 ggtccgccgt tttctccagc ttctccttga ccagctaaac gcatttgttg tccttcttct
    51481 acaccagctg gtacattcac tttaactgaa tgtgctttct tctcatgtcc tgagccatga
    51541 caggttggac aaggttcttt gatttctttc cctgtcccat gacaaacatc acaagtttga
    51601 cggctcatca ctcgtccaag tggtgtttgg cgttctacat taatcgtacc tgcaccatga
    51661 catttatgac aagtagttgg ttgtgtgcct ggttttgcac cgttcccacc acaagtatga
    51721 cagatttctt cccgattata cttgatttct ttttctacac caaaaatcgc ttcttcaaaa
    51781 gacaagtcga ccgtatattg caaatcagca ccttgacgag gcgcatttgg atcgactgac
    51841 cgaccgcctc ctccaaagaa agagtcgaag atatcttcaa aaccaccgaa gccgccacca
    51901 gagaagccgc cgaatccacc aaatccgcca ccagctccac cagcaccgta atttggatct
    51961 gtgcctgcat gcccgtattg gtcatatgca gcgcgttttt gcgggtcact taaaatctca
    52021 tatgcttctg atacttcttt gaatttttct tccgcatcag gttctttatt gatgtcagga
    52081 tggtattttt tcgaaagctt acgataagct ttctttattt catcttctga tgctcctttt
    52141 gagagcccta agacttcata ataatcacgt tttgttgcca taggctttcc tcctattggt
    52201 tctcatcatt ttcacgtcgc ttgttatcat atcatatttt gtttgaaaca aaaaccgata
    52261 cttcaaacta tttttcaaaa gaaaaagcca aagtagcaac tttggccttc tctcgaaatt
    52321 cagtgaactg attatttatc gtcgccatcg acttcttcaa aatcagcatc aacgacatca
    52381 tctgctccgc cttgagctgc ttctgggttt tcttgagctt gttgttgtgc cgcttgttcg
    52441 tatagtttaa cagtcaagtt ttgaacgatt tcgttcaatg catcgcgttt agttttcatt
    52501 tcttcgatgt tgtttgcttc aacagcggct ttcaattcat cgcgagctgt ttctgctttt
    52561 ttcacttctt cttcgtccac tttgccttct aattctttca atgttttgtc cacagagaat
    52621 agcaatgcat ctacatcatt acgtaggtca acttcctctt tacgagcttt atctgcttct
    52681 gcatttgctt ctgcatcttt taccatacgt tcgatttctt cgtctgttag acctgaagaa
    52741 gatttgatcg tgattttttg ttctttttgt gtacctagat ctttcgcaga tacatttaca
    52801 atcccgtttt tatcaatatc gaatgttact tcgatttgtg gaataccacg aggagctgct
    52861 ggaatatctg tcaattggaa tcttcctaga gttttgttgt cagcagccat tgggcgttca
    52921 ccttgtaata catggatgtc tactgctggt tgattatctg ccgcagttga gaatacttgt
    52981 gatttacttg ttggaatcgt tgtattgcgg tcaatcaatt tagtgaacac tccacccatt
    53041 gtttcgatac ctaatgacaa tggtgtaacg tcaagtaaaa caacatcttt cacatcacca
    53101 gtgatcacgc caccttggat agcagcaccc atagcaacta cttcatcagg gttaactgat
    53161 ttgtttggtt cttttcctgt ttctttacgt actgcttcta caactgcagg gatacgagta
    53221 gatccaccga ctaaaataac ttcgtcgatt tctgattgtg ataaacctgc atcttttagc
    53281 gcttgacgta ctggtacttt tgtacgttct actaagtcag ctgttaattc atcaaatttt
    53341 gcacgtgtca atgtcatttc caaatgcaat ggtccagatt ctcctgctgt gataaatggc
    53401 aagctgattt gtgtgcttga tacgccagat aaatcttttt tcgctttttc agcagcgtct
    53461 ttcaagcgtt gtaaagccat tttgtcttga gacaagtcaa tgctgttttc ttttttgaat
    53521 tctgctacca tgtagtcgat gattttgtta tcaaagtcgt ccccacctag atggttgtcg
    53581 ccagctgttg acaatacatc aaagacaccg tctcctagtt caaggataga tacgtcaaaa
    53641 gtaccgccac caaggtcgaa tactaagatt ttttcgtcgc gatctgtttt atctaaacca
    53701 taggcaagag cagctgcagt tggttcattg acgatacgtt ctacttctag accagcgatc
    53761 ttaccagcat cttttgttgc ttgacgttgt gcatcattaa agtaagctgg cacagtgata
    53821 actgcttttt cgactttttc acctaaatag tcttctgcga atcctttgat atattgaagg
    53881 atcattgctg agatttcttg tggtgtatat gatttacctt ctacatctac tttgtaacct
    53941 gcttcaccga tatggcgttt gattgatgaa atcgtatttg ggtttgtcac agcttgacgt
    54001 tttgcaactt cccctacttg gatttctcca tttttgaatg atacaacaga aggtgttgta
    54061 cggtttcctt ctgggttagc gatgattttt gcttcgtttc cttccaatac tgctactgca
    54121 gagttagtcg tacctaagtc aataccgata attttactca taattaacgt ctccttcttt
    54181 aattgaaagt gtaagtttta tatccgcaca attattgtgc aacaatgacc atggttggtc
    54241 ttaacacgcg atcatgtaat ttgtagcctt cttgtagtac ttctacaatc gtatcggctg
    54301 gtgtatcttc agtcgctgga acagtttgta ctgcttgatg aagattagga tcaaaggctt
    54361 ctcctttagc agggattttt tcaattcctt cttcttccag tgcgttacgc aaactttcca
    54421 agaccatttc cacgcctttt ttcaaacctg ccccttgatc atctgacact tctgtggcta
    54481 atgcacgttc caggttgtca attgatggaa gtaatttttt ggctaaatct tgtgaacggt
    54541 atttttgtaa ttgctcacgc tcattttttc ctcgatttgc catatttgcg atttcagcac
    54601 gagcccgcaa gtatttatct tccatttctt ctaactcagc ttttaatttc gctgtttcga
    54661 attcttccgc ttcagcttct gaaatacccg aatcttctgc agcttcgaca tcgatttccg
    54721 gttctggctg agcatctgtc atttctttat ctagttcttc ttgattttct ttcacgatac
    54781 agtcttcctt tcattattca gtcagctgtt tgattgctct tactaagaaa gagagaacga
    54841 tcagctgcaa atagcttcgt tattcacatt acgagtttga caagtcaagc gaacggtagt
    54901 aatcagcaag tttagctgct agttctcttc gataaacatc gactagaccg aacatccgag
    54961 aataaggcat actagtaggc cctaacaagg ctattgtacc tcttccatga ccatctatct
    55021 cgtaacttgc ttgaatcata ctcatattct gcaataaatc attgcctaat tcagcaccaa
    55081 tcttgatatg aatattgcta tccatcggag tgatcatttg tgtaagtccg tctgagtctt
    55141 tcataaaaga aaacatcgat ttgaactgat caagatcttg acggggctca taatccaaga
    55201 gattcatttg tccactgaca taaaccttat cttcaaaaac atgaccaaga acggtgtcaa
    55261 ataactgaga catcccttct gtcgtttgga aatatttatg aagaatcatc ggaatctccg
    55321 tacgaagttt atggtacacc gtcatcagag gatctccgac tagacggtcg tttacaatct
    55381 gtaccatttt ttctagttcc tgacttccca tatattcggg aagagtgaac acttggcttt
    55441 ctacattccc catatctgtt acgacgatag caataatctg tcgattattc aagggtacga
    55501 tacgaaagcc agtcagtcgg cggtctttta tttcaggtcc caatgaaaaa gtcgtatagc
    55561 ttgtcagctc agataatatc tcagcagatt gcttaataat ctcattgatt tcatgaaatt
    55621 ctctgcctag agactgacga atcagcagca aatcatcttc tgctacgcga gcaggtttta
    55681 acaaatgatc cacgtaataa cgatagccta aagcagatgg aatccgccca gaagaagagt
    55741 gagtcttcaa cagcaatcct tcatcttcta atgctttcat atcattgcga atcgttgctg
    55801 agctggcctt gactccctca gacatcaatg ttttggaacc aacgggcacg ccactactcg
    55861 tatagtgttg gatgatcaga cgtaaaatgt cgttttgtcg ctttgttaac atcttcctca
    55921 cctctcatta gcactcatat attctaagtg ctaatccact tataaatata gcaagaagcc
    55981 cttctcctgt caagagaaag actccatttt ttagcactct aaacacaaga gtgctaattc
    56041 taaataattg atgtaaatcc agttatatca acgtttcaat agtcctttat tgtatttttg
    56101 aacttttttt atttaaattc agataaaaaa caaatattct ttaaactatt tttcaaacaa
    56161 aaagcgctca aacacattgt tccccaaaaa ggtccctctt ggtgtcaaat aaacacggtc
    56221 ttcttcatta acaagtaacc cttcttgctc taattccctt agcacatcac cgtacaccga
    56281 ttcaattgtt ttttgatagc gatcatagaa atgtttttta gtaatccctg ttttttttct
    56341 tagtcctaag aacatttctt cttctatttg attttttcgt gtcaattttt cttcttccaa
    56401 taccgggcgt tcatttgctc gtaatgggcg taaatagtgt tggattggtc ctttgttgcg
    56461 gtaacgaata tctccaagat aaccgctagc accagctcca aacccaaaat agtgggcatt
    56521 gttccagtac atgaggttat gttgagattc atgtccggag agcccaaagt tacttatttc
    56581 atattggtga cgtccatgct tttccattgc ttcaatcgtc tcttcaaaca ttctggtttc
    56641 cgtttcctga tcaggcagtt cgagtcttcc ttgtcgtacc cagttcatga acattgtttt
    56701 gttttcgagg atcaatgagt acaaagaata gtgaggcaga tccaaagcca aagctttttc
    56761 caaagtatcc agatatcctt ctagtgtttg tcccggtaat gcataaatca aatcgatgct
    56821 tacattggta aaattttctg cttctaaaaa ttgcatagtt tgatacacat cttctgcggt
    56881 gtgtttacgt ccaatttttt tcaataagcg attatcaaat gtctgcactc ccatggataa
    56941 acgattgacg ccatagtttt tcattacttg aagtttttca cgggtcaaat cacctggatt
    57001 cgcttctaca gtaaactcat taccattttg aaaaggcagg atctctctag cacctgataa
    57061 cagtcgatca agttgtttag cagataaaga agttggtgtc ccgcccccta cgtaaagtgt
    57121 ttctaaattc gctgtcggat gactttctag cattattttc atttcattca gcagcatttc
    57181 cacatactca tctactggct gcccttctaa aaaaacttta ttaaaatcac agtaatagca
    57241 gatatgctcg caaaatggga tatgaatgta cgcagaaacc ttgttttctg cgggatttat
    57301 tgtttctatc attgaaattc tttctcctta cgtcgaaaag tcgtgcctgt tttcgacctt
    57361 cttaaaatcg cgttcaagca ccaactcatt gaaataagcc gcatatttag aatcaaggaa
    57421 acctagctct aaaaatgctt gcttattgtc atcggagcta cacggtgctt ttacagcctc
    57481 tcgataaacg gtaatcgcaa agctgacctt cggcattaag tcaaaatctg caaaaatatg
    57541 aaaagctatt ttcacagatt cctccttaag tgctcagacc acaacgcttt gcttacaacc
    57601 tctcatatac gcatactaaa cgtatttggc gaacaaatcc actaaaaaat ccaagaatcg
    57661 acttcttgga tgattttttc tttcattaaa ctggttacct agttatatat ctctagggtt
    57721 gttttcatgt ctgagtgccc gatatgattt atttttcgtt tctataatta ctttttgcct
    57781 tccagtttct tttaatattg tactcaagca agtgggaatt ggttcttttg tcatccatgt
    57841 atgcaaaatg ttataatgct ggtaaacaaa aatgattacc tgtcattttt atttagttcg
    57901 tatttaatta agttgactat ctgtatactc tgtctaaaac ttaagaattg ttgttttcgc
    57961 tgtcgctacc caattttaat gaatgtctgt aggttaaaac tgttgtcctt gttatagata
    58021 gtaaaggaga gcttgaaaat gaaaactgcg attacgtttc tattagagga atatgccgat
    58081 tgggaaggtg cttatattac tagcacacta aaccaaaatg agaaatggca aaacaaaact
    58141 gcttctatcc aatcagaggt cacttccatt ggaggattaa aaacaaaaat cgattactta
    58201 atcgaacaaa tacctgaaaa agttgacctt tttattatga tcggtggcaa ttcatgggac
    58261 ataaaaaatc atcatttata tcaaataatc gataaattgt taaaaacaga cgtaccagta
    58321 gctgctattt gtggggcagt tgattattta gctcagagcg gattattgca aggttacaaa
    58381 cacaccggaa atgcgcaatt tccttggtta gaatcggaaa attatcagaa taaagaagat
    58441 tttatagaac aacaagctgt gaaagatcgt aatttgatta ctgcgaatgg aacagctcct
    58501 atagaattca cagacttgat tcttcaagca gtccattttg aaacagaaga aataagagaa
    58561 aaaacgattc gtctatacaa acttggattc tatgattact ataaaaagta cggagatcct
    58621 ttctcctaat cattctcttc aattaaatac tccttatcaa tagtgtgaca agtaatttta
    58681 ctgatgatta tttgtcacac tttttctgac atttatcaaa gaagatacac tctatttata
    58741 ttcatagaca aggttttacg gattcaaaaa ttcaggatta tgctatactg gtattaaaaa
    58801 aataatgagg tattttatat gaaaaagtta ggttttattt tattgttggt ctctttattc
    58861 cttgtaggat gtacgtctcc tagtaaagaa aatagtgatc catctgcgac cacagacaaa
    58921 agttcaatca gacaaaccag ttcagctgaa aaatcaagta ctcagaaatc agcttctact
    58981 gaaacgaata catcttcaac aagcagtaaa gtctcagagc ccaatacttc ttctacatct
    59041 agtagtacag ttgagacaaa tatttcttct tcaacaatag acacaacctc ctcacagtct
    59101 tctcagtcaa tagatccgtt agcaggatat tctgatctac aaattgagta cgcacgtgtt
    59161 tggctagcta ttagaggtaa tacttttaga gatacatcgg gtgatttcga attacatgtt
    59221 attcattatc ctgcaggaac acctatcgcc ccttatgatg cagggagtgc agtctatccg
    59281 aaagatgtgg ttatgctcac tgggaaatac agttaccagg gagttttagt gtattcaagt
    59341 aaccatgacg ggacaatcac tagttatcca gttccttcac attggcaaat gcctgcagat
    59401 caaacatctt atccagcgtt cattagagaa acaactcaag aaatcattga taatgcatct
    59461 gtagtagcta ttcctacagg aaatcccaat gacgtgaaac agttaatcga tgtgacagtt
    59521 atagataatt agactttcta atatgttata caaaaagaag ctgacagcat tttgtcagct
    59581 tctttcactt tcttttctat ttagatttat tggtctttga tagactccaa ggcaggaaaa
    59641 aattttttaa ataaacgttt gcaaaacagt cgcttttcta tcttctaccg ctacttctgc
    59701 ataggcacca ttaatcaatg tcagttgtgg cggtacatga ccacaatcaa tatcatacaa
    59761 gatcggtagt tttaattcct ttgacagatc ttcgtataca tccttcattt tataatctaa
    59821 caaatcctct gccgcacttc taccgaacat gatccccgag ctgccatcaa accagcctgc
    59881 cagtttcatc tgaacaagtg atcttcttaa atcaactgac gatagctcac agttttctag
    59941 aaaccacaag atcggctttc catcattata ctttctttta aaagattgga catctccata
    60001 aggagtaccg attaaatgcc tgatcgtatc aatacaacca cctaataatc gtcccttcat
    60061 ccttactgca tctccgctga ctgattgcca atttgttggt tcagtgagat ggaaaacaga
    60121 agatgatgaa tgctcatggg gccacacttt ttgatacttt tcagaagatt gctgtagaat
    60181 cgattctcct tctcttgttt tcagtacact ttcccacatt gctgtcgttt catccaagta
    60241 ctctcctctt aaatcaataa ggttagttcc atgtgcagtg gctatccctg tttttaatgt
    60301 gacagcaagt agcaacgtac taatatctga ataacctact atccattttg gttgtagagc
    60361 atcaaaatcg acaaaatcga gaatctcaat caataattct cctccccaag tcggaaagat
    60421 catttggata ttttcatctt gcatcatttg attgaattca tctgctcgtt ttcttgctgg
    60481 acctgatttt tccttatctt gcgtccaaag cgtctttcca gtaactactt ggaaagattt
    60541 ttcttccatt ctctttaaag ctgattcgag taacgaatgg tgttcctctg atacgcctga
    60601 ggatggtgca gtaaccccaa tcgttgcatt tctttctaat aatggataac ttatcatgtt
    60661 gcttcacctc caagtatgca ctattttact tggttaattg tttttttcgt ttgccggcat
    60721 caaaaatatc ggcatctcaa gtagctggat gattttgttt aagtcaaccg tttggatgac
    60781 catcgtttga tctggtctac ctggtgcaaa aacaagtttt tcatttgata agagctcttc
    60841 atcaataata atcggaatct gtttttcata accaaacgga gaaacagcgc cctgcttttg
    60901 tcccgtttgt tcttccatgc gttctgatga aacaatagaa agccttttac cgacgatctt
    60961 ccctaatgct ttgaaatccg tttgtttcgt agtaaaagtc agatatacgt agttattatc
    61021 ttttttatct tttaagaata agcttttggt ctctgtacct gtaaatcctt gttctttctt
    61081 tattaccaaa gcatcttcat ttgtataaat ggctcgatga tgatacaact caaaatatat
    61141 attttcgtgt aagaatttct ttgccaagtc aatcattttt atgtctcttt tctattttat
    61201 tatttgagac atcttatcat ataaatatag cggttacaac attacttgtg ttttgttcgt
    61261 tttttataca taactattgt ttttctggta aaataaatca aaccacttaa tggaggcgtt
    61321 ttagaatgga aaaatttcag ccgatcatca atcaaatcaa agaaaaagaa catcaacaaa
    61381 agatcaaaga cctttttgct aagataacag aaacgtatcc ccagctagac acaactgtaa
    61441 aatggaacca acctatgttt actgaccatg gtacctttat tattgcattt agttttgcta
    61501 aaaatcattt ttctatcgca ccggaaaaag cagcgattcg tgcccttgaa aaaaatatcc
    61561 aagaagcagg ctacgtatat acggataacg tcatcaaagt tccttggaaa agtgtaatca
    61621 actgggaatt gattgaacaa ttgatttcat ttaatattga agataaaaaa ggtcatgata
    61681 aattttggcg ataaagcttt atacgaataa accttttact ggcgaggaaa ctattcatca
    61741 ccttatacag gttttgttca atcctatcct ttttatcatc cctggttaaa cacttaattg
    61801 acaaagtatc tgctattttt ataaggagtc tttcttgtgc tgaaaaaaat cactgattga
    61861 atggctttga attttctact tagtaaaatt attttttcag caattttcct gcaaaacttt
    61921 tgaataagga aaaaatacga gaaaatatca gtgatctttc ataatactgc ccattatttt
    61981 caggtatatt taaatataat atcactttag gagagaacga atttctttag agaaataaaa
    62041 gttagaattt tctgacttga tttttacaat gaccttaatt aaaatcgttc tttctacatt
    62101 tcgtgattaa gcaaatatca actaagtcag tagaaccatt cacataggag ggtgaacatt
    62161 gaaagatttt tactcagtaa atgaattagc cgaacaatta ggtgttacta cacgttctat
    62221 cagaaattat cttcatgaag gaaaactaaa aggaacaaag gttggcgggc aatggaaatt
    62281 ttctgaacgt aatctttttg agttcctata cggagatcaa gcagaggaag cagcaaaaga
    62341 aatgcagcga ttcatgctaa atgcaccaat cacgatgcgt ttcaaccttc aatatcgtga
    62401 ttttacagca atcaatcaat tccgagaaca attagtccag taccataacg atgtttacgc
    62461 aaataaaaaa gaccgtcttt tacaatacga tctttataaa gacaatcatg cggagatact
    62521 aatcggtggt aacttcaatt atgtcgtaaa ctttagtcaa tggatcaatg aaaaattatt
    62581 gatccagaca gatatttccc ttgtatctta aacaattaaa aagcgctaga aattccagag
    62641 atgttggaaa ttctagcgct atttttttat aagtacttac tgtttggttc aaacaaatat
    62701 ttttttaata aatgaaattt taccatcttt atcctcaaat aaagaccgtg accatgcttc
    62761 ctactacgat cagcaataat ccgataatcg ttaatttttt ttcttttggt gtcttatttt
    62821 catgcaggat gtacataccg cctaatgtag agataactac gtttagctgt gtaatgatat
    62881 atgcagtagc aaccccattt tcatttgctg aaaaaatata agccaatgct gacacactaa
    62941 agatggctcc aacgatcgtt gctttccaac tcttgtcttc agaaaatgcg gttggtttac
    63001 ggaaaatcac ataaatcact gcccctaaaa agacaccgat catttgcgga aagaaaatgg
    63061 aaagtccgct tgcatcaact agtttaggca atgcactgta tacccaataa ccaatacttg
    63121 ttgatgctaa tagactaatt ccttttgtga taccgccttt ttttccagga tcatcactga
    63181 ttgccgttaa agcagaacca aatacaagaa gaatgattgc tgctgctcca atgattttcc
    63241 ccatacttcc agaccattct ccaaaagcga agacaccaat caacgaggtt ccgactaact
    63301 gtaatgcagt cgaaattggc atcgttttag aaacaccaat caagttgaaa gatgtatact
    63361 gtcctgtttg tccaataacc caaaatgcac cagaaagtaa actaatcaaa aatgtagtca
    63421 ctgaaatacc agctggagaa gcgaataatt gaacgagtaa gccgacaagc accgctccaa
    63481 taccagttcc taatatctca tttgttggtc tgccaccaat ctttttcaaa atcagtggct
    63541 ggatccccca gccaactgcc gggatcaatg caatcaataa acccattttt attcaccctt
    63601 atccttttcc accttggaaa gaaggatata aagtcatccc accatctgca aatagtgtaa
    63661 tacctgtaac ataactggat tcgtctgaag ccaaccatgc agctgtcgcc gctatttctt
    63721 ttggttcacc tacgcgtcct agtgggatca tactttccaa gagttctttt tgttcaggat
    63781 catcaaattt tgccgcatta ataggtgtac ggatagcacc agggcctata ctattgattc
    63841 tgattccctt cggtgcatac tccattgcta ccgtttcggt aaataatttt accccgcctt
    63901 ttgaagcagc gtaatgagca aacgttggcc atgggatctg ttcatgaaca gaagacatat
    63961 tgatgatatt tcctttttta ttattctctg taaagtaatt taaagccgct ttcgttccga
    64021 taaaaacgcc agtcaaattg acttttaaca ctctttccca atcttcaagg ctaagttcat
    64081 gggttggatg ctgattttcc atcccagcat tattaaccca aacgtccagt gtcccaaaat
    64141 tttctaaagc cgtatcaagt aaacgctgta ttccttcttc agaactgaca tctgcttgta
    64201 cagagactgc ttttccgcct gcctcttcga ttgctttgac tgctttttct gctccttctt
    64261 tatccgagtt atagttgaca actacattca ttttttcttt cccgaatcgt tgagcaatcg
    64321 ctgttccaat cccctttgag ccaccagtta ctactgcgac tttgttttct aattccttgt
    64381 acatagtacc cactcctttt tcatacctaa acctgttatt acggataact tttatttccg
    64441 ccttaaagtg agtgtacacc aagatatata gtctaaagca aatgatacgc tctagcaatc
    64501 gttttcatga attgctagtg tccttttatt tctataaaga aagaggttgt gacagaagtg
    64561 gtcagcttca agaaatttcg gcttatttcc gaagaagcta cttctgaaaa accatttatt
    64621 tggaaaaaaa ggctgtgaca agacttttgt cacagcccct ttcctgggct tatttatcac
    64681 ccattttatt gtaattgcta gttatacata aacaagagat tttatgcata atgttttatt
    64741 gctgagaaaa atattcagct gttgcttgtt catcctcctt gagttgttca atcaattcct
    64801 ctacactaga aaatttcact tgatctctta aaaattgatt ccagcgtacc gcgacatgtt
    64861 caccatagat atcttgatta aagtccaaaa tatacaactc tacagtcagc tcccgtcctt
    64921 caccgaatgt atcattatgt ccaattgaac ccatggctgg ataccatgtt tccccaattt
    64981 ttatttccga cacataaaca ccttctttag gcaaatgaac cgtgctcttt actttgacat
    65041 ttgctgtagg gaatcctagt agtctgcctc gtgcatcgcc atggacaact accccttcta
    65101 cctcatatgt gcaacctaat agttttgctg cttcttttac ttgtccgctg tctagtaatc
    65161 cacgaatacg ggtagagctg attttttcac cttgttcttc ttctttagaa actgtgacga
    65221 ttttgaatct tcctttggca tattcaggaa aatgagcgac atctgcaatg tcttttggtc
    65281 catacgtata atcaaaaccg gaaacagcat attttgcatg taaccctacg atgtattgat
    65341 caacaaattc ctgcggtgct aaatgagcaa aagaagaagt aaaatcaact tcatataaat
    65401 aatctatacc caaagcggcc attttttctt ctttttgctt aaggctagtc aaatatttca
    65461 cgctgctagg atcgatcttt ttaaagacaa tagatggatg ctgattgaaa gtcatcaatg
    65521 ctaatttcaa tccttctttt tgtgcaattt ccatacctgt ctttatgact ttctggtgtc
    65581 cgatatgcac gccgtcgaaa aatcccagca ctaaaacgac atcgtcttct ggaatttgtt
    65641 ctgattggta aggatgtctg atcttgatga tattcattcg ttattcctca tttctcaata
    65701 ctttactagg ttttaatttg tttttttctt tcgggtttgg ctgataaata ctgacaactt
    65761 ttcctttata aaacaaagca atttcttctg acggcatttc tgggagcgca aatacagtat
    65821 aatcaagtct cataccgttt tttactttct gccatacttc atcagtaata tctactcgtt
    65881 tgaaccgttc cactcctttt tctattggca gcaaacaatc atcgattgtc ccatttttca
    65941 cagcttgagc tacttcttct aatgtcagag catccttctg ggacataccg gcacttgctg
    66001 ttcgggtcag atcagacatg tgcgcagggt aaccaagttt cttgcctgta tctacagcta
    66061 atgtgcggac ataggttcct ttcccgcatt ctacttcgaa gcgccaagaa atggttcctg
    66121 tcacttcgtc tcttgtcaat tcacttgtcc ggataaaacg gtaaatctga gcctttctaa
    66181 caggacgctc cactgtttca ttattgcggg catattcata taaccgctta ccgttgactt
    66241 ttaccgctga gtacattggt ggtatctggg tgatctcacc aataaatgaa gccatcactt
    66301 catctatttt tttttcagat aaagacatat ctactggttt tgtttctacc cgttctccgg
    66361 atcgatcttc cgtcgttgta ctgaaaccta gagttatctc gcctacatag attttcccag
    66421 aatctgtcaa atattcgata acttttgtgg cttttccaat acaaatgggc aacacaccgt
    66481 ctacgtctgg gtcaagcgta cccccatgtc cgattttttt cgtatgtaag atttttctta
    66541 atttgaatac gcaatcatga cttgtcattc cgcgttcttt ccataaaggt aataacccgt
    66601 ccatgtcttt tctccatttc atttttgatt taactgaatt attataacac attgcatcaa
    66661 ttactgacga atttgacatc ataatgaacg gtttttattt ttcggcaata aaaacgtaac
    66721 aaaattcatg ctcacgtaaa tagaaatcat gttatgcttt tttaaaggag ggaatagaat
    66781 ggaagatttt ttctttgcac catttgattg gatttatggg tggcttacag gtaaatagtt
    66841 tggttttcac ttcccaaaaa cgaaaaaaaa gactggccat tcttccagtc ttttttccgt
    66901 tttttttatt tattttttca gtttcttaat caatgtaaaa aattctattt tgcgggatcg
    66961 attttatcat tttattggtc aagatttttc catttccaat ccaatacttc tggcagatca
    67021 ataccatttt cacgaatata gttttgatgt tcttgtaatt tctgatccat ttttttcgca
    67081 aaatcttctg cttgacttcc tttgattttt aaagctgcgt cttttgccaa atgataacga
    67141 tcaagttcat ttactacacg catgtcaaat ggtgtcgtga tatctccatt ttctttgtag
    67201 ccatgaatca ttaaatgatg gttatgacga tcaaagaaaa tcgtgcggac caatgtttca
    67261 taaccgtgga aagcaaataa gatcggtttg tcttttgtaa aatattgatc aaattcttca
    67321 tcgctcaacc cacgcggatc ttgacttgga tgacgtaatt tcaataaatc tacgacattg
    67381 atgaaccgaa tttttagttt tgggaattct tccagcagca aagttacagc tgctaatgct
    67441 tctaagttag attccgttcc tgcagcagca atgaccaatt caggttcctc ctcttttgct
    67501 gtcgaagccc aatcaatgat tttcaagcct tcattcacta agacggctgc ttcttctgct
    67561 gagtaaaatt gagcacgcgg atgtttggaa gagatgatca aattgatttt ttctgacgag
    67621 cggaatgctt tatccatgac tgcgagcaat gtatttgcat ccgcaggcag atattcacgg
    67681 atgaactccg ccttcttttc tgccaaatgt gtcaatattc ctggatcttg gtggctatat
    67741 ccattgtgat cttgctggaa gactgttgag cttgcaatga gatttagcga aggataatca
    67801 tttcgccaag aaaggtcatg tgatttccgc atccatttga agtgctgagt caacatagag
    67861 tcaaccactc gcaagaatga ttcgtaactt gcaaaaaacc atgccgtcca gtcagaacgt
    67921 acccttctaa gaacccttca tcttggtgtt ccgataattg actgtcgatg acgcgaccag
    67981 atggcgaaag ccattcatca ttttctggtt cgattttttc catccattgg cgatttgtcg
    68041 ttttgaaaac ttgattcaat cggtttgatt ttgtttcatc tggtccaaat atacggaaat
    68101 tttctggatt tttctcaatg atctcgcgaa cgaatttacc aagttcggtc atatcttctg
    68161 ctttaacgga gcctggtttt tcaaattgca aagtatattt tttccaatct ggcataataa
    68221 gcggtcttgg atcgattcca ccattggtga taggattttt tgccattctt tggtcaccag
    68281 taggcgcgat ttctctgatt tcttctaaaa tacgtccttg tgcatcaaat aatttttctg
    68341 gttcatagga tttcagccaa cggagtaaag catctgcatg atccatatgt tcttgatcta
    68401 caggaatcgg tacttggtgt gctcggaagg ttccttcaat tggttccccg tcccattctt
    68461 ttggaccggt ccatcctttt ggtgtgcgta cgatcaatac tggccatttt ggcatcacga
    68521 catctgttgc tgtcttcagg cgagcttctt tttggatgga tttaattttc tcgattgctt
    68581 gatccatttt ttcagccata acaggattta atttttctga atcatttcct tcaataaaga
    68641 aaggttccca gccaagtccg ttaaagtaat ttgctaattc tccatctgat ttacgtgcca
    68701 agatcgttgg gttggctatt tttgcaccat ttaaatgaag gatcggtaaa acagctccat
    68761 ctatcactgg attgataaag acatttgaga accagcttcc agctaaagga ccggtttctg
    68821 cttcaccatc accaatcacg acagcagaga ttacttcagg attgtctaat acagctccga
    68881 ctgcatgtga aagagagtat ccaagctctc cgccttcatg gatagaacct ggtgtttctg
    68941 gtgctgcatg agaagcaatg cctccaggaa atgaaaatcg tttgaataat ttttgcattc
    69001 ctgtctcatc ttccgttact tctggataga tctctgtgta acttccatct aaataagcat
    69061 tcgataccat gacttgtccg ccgtgtcctg gcccttcaat ataaaacatg ttcaaatcat
    69121 atttattgat gactcggttc aaatggacat aaataaaatt ttggccagga atcgttcccc
    69181 aatgaccgat tggatgtttt ttgacatctt cgggtttcag tgtacgtctc agtaaggggt
    69241 tatctttaag ataaagttgc ccaacagaaa gataattagc agcacgccac caagccgtca
    69301 ttttatcaaa gtattcttta ctagaataat ccatacataa cactcctttt cattattact
    69361 cttattctag cgcagatact cccaattgaa acctaataag cacttctgtt catttgtttg
    69421 gattttatat ctagccaaat gaacaggtat aaaaaaccac gaaatttttc ctttcgctga
    69481 cgttttttac attgatccaa aaaacttgtc gttatcacaa tggctgttcc gcagttcatt
    69541 tcgctcctca tcatgcataa tttgctgaat gacgctgggc cagttaacac attgctggaa
    69601 aactggggct ggatcgagca attcctttcc tgattgatcc gttttatgta aaagtctctg
    69661 ttatctttgt caatatgtga attggtatcc cagctactat gctaatttct acagggatta
    69721 tccaaaattt ggatcgtgac caaatcgaag cggcgtaatc ggaaatatca ataacttcaa
    69781 cgtgattttt cttttaactg tcaacggacc gacaaactca aacttttatg gtgcaggttc
    69841 cactgatctt ctagttactt ggctatacct gactgtcact aaaatagatt acaatctagc
    69901 ttccgttatc ggtatcttga tctttatcta tatgcaaaaa tttatatact actagaaaaa
    69961 agaaagtcga attttttact tttctttttc tcttttttgg ttagctgaca cgccgcaaga
    70021 ctaaagtcat ggaactctta ggtaatacgt cttaatgaaa acaaaaaaat cccgcaaccc
    70081 ctgatttcac aggatttgcg ggagtttttg attagtcttt gttcaagtcg cgaagcaatt
    70141 catcgatatg gttgccatag acaactgatt catcaagttc aaagaacaat tcaggtgtct
    70201 tataaatact tagattgtgc cctaactctc gacgaatcaa tcctgatgct ttattcaatc
    70261 catcttgtgc tgttttctta tctgatgcta agtcagataa aatgctgtaa tagatcgttg
    70321 cttgctgtaa gtcccccgta actttcacat ctgtgatcgt tacgttctcc acacgagggt
    70381 cacggacctt tttgcgcaaa atatcattga cttcttttaa gatttcttga ccgactcggc
    70441 ggtcacggta gttagccata atgattggcc tccttttatc agtttttagt catttttgac
    70501 ttcttccatg ataaatcctt caattacgtc atctactttg atgtcattga atttttcaat
    70561 cattgcacca cattcataac ccattttgac ttctttcacg tcatctttga atcgtttcag
    70621 acttgcaagt tggccttcat agattacgat tccgtcacgg attacacgga caccgctatc
    70681 tctacgaata tatccttctg ttacataggc acctgcaatc gtaccaactt tagaaacttt
    70741 gaaggtttca cgaacgatca tttgaccggt gattttttct tcaaattcag ggtctagcat
    70801 ccctttcatc gcagtttcga tttcttcgat ggctttatag atgatacggt gaagacgaat
    70861 atcgacttct tcagtatcag cttgcacttt tgcctgcggt gtaggacgaa cgttgaaacc
    70921 gatgataata gcgttgctgg ctgctgctaa ggttacatca ctttcattga ttgctccgac
    70981 agctgaatgg acgattttta cacggacacc ttccacatca atcttcttca atgatgcagc
    71041 cagtgcttct gctgaacctt gtacatctgc tttgatgatt acgttaactt ctttcaattc
    71101 gccttctttc aggctttcaa ataagttatc caaagtcaca cggcttgtgg cagcacggtt
    71161 ttctaataat gcacgtttcg cgcgttcttc acccgctgca cgtgctgtct tttcgtcttc
    71221 gaagactacg aaacggtcac ctgcttgagg tacatcattc aagccagtga tttctactgg
    71281 cgttgcaggt cctgcttctt tatcgcgacg gccaagatcg tttgtcatta cacggacacg
    71341 tccgtaagta ttaccgacaa cgattgggtc accaacatga agtgttcctt cttggacaag
    71401 taaggttgac acaggacctt tacctttatc aagacgtgct tcgatcactg ttccgattgc
    71461 gcgttgtgtt ggatctgctt ttaaatcttc tacttctgcg actaacagga tcatttccag
    71521 caattcttcg atgttttggc cgaatttcgc tgagatctca acaaagatcg tttctccacc
    71581 ccatgcttca ggaattaact catactcact taattcttgc ataacatgtt gagggtttgc
    71641 acctggttta tcaattttat ttacagcgac gatgattgga acgcctgcag ctttggcatg
    71701 gttgattgct tcaactgttt gtggcatgac gccatcatct gcagcaacaa ctaagatcgt
    71761 gatatctgtg atacttgctc cacgtgcacg catacttgta aaggccgcat gtcctggtgt
    71821 atccaagaaa gtgattggtt taccatcaat atcgatctgg taggcaccga tatgctgtgt
    71881 gattccgccg gcttcgccgc ttgttacacg tgaatggcgt aatgtatcca ataaagttgt
    71941 tttcccatgg tctacgtgtc ccataatcgt tacgactggc ggacgtgaga ctaatttatc
    72001 tggatcgact tcttctgcct cgaagaattt atcgatatca gcaatgtcaa cttggacttt
    72061 ttcttgtggt tccatgccat agtccgtcgc taacagttca atcgtatctt tatccagtgc
    72121 ttggttttga ttgaccatga caccaagcat aaataatttt ttaatgattt ctgctggctc
    72181 acgatgaatt tttttcgcaa tatctgctac gttcatacct tcagtatact ctaatacatc
    72241 tggcaattca cggaatttgc gtggtggtac agctggttta gttgattgtt gctgtttgcc
    72301 ttttttacct tttttattat aacgattacg gttattatta ttaaatttgc cgcgattgtt
    72361 attgtttggt ttgttgttat tgttagtacg gttttgattg ccgccttggc tcgttccttg
    72421 acgattttgg ctgctggtat ttcccgtatt attttggttt gttgttggtt tttttccttg
    72481 attcacttga ccgctccctt gaccgcgatc ttgataactg cggttatttt tatttttttg
    72541 ttgattgttc gttgtttctt ttttacgttg atcgttcggc tgttgattgg ctggttttct
    72601 gcttgcttgt tgtgcagctt gttgtttcgt gcttgggttt ttgaacgctt gttgcaattt
    72661 cttctcatca ttgctagtaa tcgcacccat atggtttttc acatcgatgc caagttgttg
    72721 tgctttttcc acgacgtctt tactagattt tttgagttct tttgctaatt catagattct
    72781 tttgttgccc atgcaatcac cttcctaacc ttcaattagc tccttggtct tcttcgcaaa
    72841 tccggcatcc attattccga ataccttgcg aggttttccg atcatctgcg tgatttctgc
    72901 ttcagaaaat agctcaaagc aaggaacttc ataatatgaa ctcttatctt ttatcttttt
    72961 tcttgtattc tcgcttgcat cggttgccac aaacaccaat tttgcttttt gtttgcggat
    73021 ttcagcaatg gtcagttctt cacccgtgat tagttttccc gcgcgcatcg ctagaccgat
    73081 gagattcatg gctttttgcc gattaactgt attcattttc caaataactc tttacgtgct
    73141 ttttggtgag tgacatagtc aagaagttct tgataaaact catctgttaa tgttgtttcg
    73201 agtactcgat cgagaatttt tttatcccaa gcttgttgta cttcttccgg ctcaagtgag
    73261 acatacgctc ctcgtccagg catttttcca gttggatcga tcgatacttc cccttctttt
    73321 gaacgggtga ttcggaccat ctctttttta ggtttcattt cacctgaaac cacggatttg
    73381 cgtaaaggaa ttttcctttg tttcatctct ttgcctcctt actaaagtta agcttctggt
    73441 ttttcttcga ccgtttcatt gttgaatgca attgtttcat attcatcgtc tgttaaatct
    73501 gactgaacga ttgcttcatc atgcagttct tctgtttctt tttgttgttc ttgattttca
    73561 taaaattccg tcatgtcaga ttctgatttg atatcgattt tatggttagt caatttagca
    73621 gctaaacgtg cgttttgtcc gcgtttaccg attgctagcg ataattggta gtctggaacg
    73681 acaactgtgc aggcctttgg atttgtctca tcgaagatca catccatgac ttgtgcagga
    73741 ttcaatgcat ttgcaatgaa tacagctgga tcttcattcc attcgacgat atccatgttt
    73801 tcgcctttta attcattgac gattgcttga actcgttgtc cctttggccc gacacatgta
    73861 ccgactgcat cgatatttgg atcatttgag cgaactgcca cttttgaacg atcgccagct
    73921 tcacgggcga tgctgacaat ttcaacgatt ccatcataga cttctggtac ttcttgctca
    73981 aataagcggc gcaataggtc tggatggctg cggctaacaa atacttgcgg acctttagac
    74041 gtattttcta ctcgggaaac ataaactttg attcgatcat gtggttgata aaattcattt
    74101 ggcatttgat cttgtttaga aagaactgcc tcaattttac caagattgac ataaatataa
    74161 cgtttatcct ggcgttcgac gattccttgc atgatgtctt tttcataagc actgaattcg
    74221 ttataaataa tcgttctttc tgcttcacgt acacgctgta aaataacttg tttagccgtt
    74281 tgcgcagcga tccgcccaaa atcttttggt gttacttcaa aacggatcgt atcaccgatc
    74341 tcatatgctg gattgattaa aagtgcatct ttcaatgaga cttccaactg tgaatccatc
    74401 acttcttccg ttacttcttt taccgcatag acatggatct ttcctttttt ctgatcaaat
    74461 tccacttcga cgttttgtgc ttggccatag tgacgtttgt atgcagaaac caatgctgct
    74521 tctaaagcat cgatcacgat ttcttttgag atcccttttt cagcttctaa agcgtctaac
    74581 gcatttaaca tttctttact cattttttct gattcctctc cgtgattaaa attggatagc
    74641 taagcgagct tttgcaatat tttttcggtc aaaagtcaat tctttttctc gtgtttttat
    74701 gcgtattttc aatgtaagct gttcagcatc aaatgattga agaaatcctt catattgttt
    74761 ttcgccatct actggttggt ataaggagac atggacataa tcaccaagtg ccttttcata
    74821 gtcgctttct tttttcaatg gccgctctgc tcccggggag gatacctcca ggaaataagc
    74881 ttgaggaatc ggatctggat ctgctgcatc aagtttttca ctcagtttct cactgacaaa
    74941 ggcgcattct tcgatatcga taccgccttc tttgtcaata aatactcgta agaaccagct
    75001 ttttccttct tttacaaatt cgacttcgac aagttcaaaa ttttgttcat ctaaaatcgg
    75061 tgtcaccatt tctgtgactg tttcaacgac gctactcaaa agtttcgcct ccttaaaaaa
    75121 ttaagtgcgt aattccatta aaaagagtga gcgaaaaatc cgctcactca cagttagtat
    75181 cattacctat aagaactata ccatactctg cttaaaatta caagcagaca ggaaaacaga
    75241 tgcttatagc atatcgaata acgataattg attttcatct ggtagatctt tcaatacgcc
    75301 attgtcgttc atatattcga tcaatgtttt tgaaacttta ccgcgggtgg caagatcttc
    75361 tttggataaa aatggaccgt cttttcttgc ttcaacgatt tgttttgcca cgttggttcc
    75421 caaacttggg acagctctaa atggtgcgat caacgtatca ccttcaataa caaagttaac
    75481 ggcatccgat ttatacaaat caatcattcc aaatttgaat cctcgttcca gcatttcatt
    75541 ggctaactcc agcactgtca gttgattctt ttcttttacg gaagcatcta atcctttgtc
    75601 cgtgatttct ttcattgctt gtttcacagc atcttttcct ttgcacatgg agactagatc
    75661 aaagtcgtct gcacgtacag aaaagtatgc acagtaatac aaaataggga aataaacctt
    75721 gaaataagcg acacgaagag ccatcaatac gtaagctgca gcatgggctt tcggaaacat
    75781 atatttgatt tttgaacaag aatcgatata ccagtcgggc acattatttt ctttcatcgc
    75841 cgatagatag gtttctcgca attcatcagg gatcttgttc cattgtcctt tacgaacagt
    75901 ttccatgatt ttaaatgcca tcccgctatc taatccagca tggatcaaat aaaccataat
    75961 atcatcacga cagccgatta cttccgccag tgtcgcatct cctcgtcgaa tcaattcttc
    76021 cgcatttcct aaccatacgt ctgtaccatg agatagtccg gaaatttgca gtagttctgc
    76081 aaaagttgta ggatgcgttt cttctagcat ccctcgaaca aaacgagtgc cgaattctgg
    76141 aatacctaat gtccctgttt tggaataaat ttgttcctga cttactccaa gtacttcagg
    76201 accggcaaat atccgcatca cttccgggtc atccgtaggg atcgtttgtg gatcgatccc
    76261 tgataaatct tgaagcatcc gaataacagt tgggtcatca tgccctagaa tatctaattt
    76321 caatacatta tcgtgaatcg agtgaaaatc aaaatgagtc gttttccatt ccgaattttg
    76381 atcgtctgct ggatattgga tcggcgtaaa atcatagaca tccatataat cgggaataac
    76441 gatgatcccc cctggatgct ggccggttgt ccgtttgact ccagtagcgc cttttgctaa
    76501 tctgtcgact tctgcacttc gaaactgcag attattgtcc ctttcgtatc cttttacata
    76561 gccatatgct gttttgtcgg cgactgtacc aatcgttccg gcacggtaaa catagtcttc
    76621 gccaaacaat actttcgtat agttatgggc ttctgcttga taatcacctg agaagttcaa
    76681 atcaatatcg ggcactttgt ctccatggaa tcctaaaaat gtctcaaatg gaatatcatg
    76741 accgtctttg tttaagcgtg caccacattt tggacattgt ttttctggca tgtcaaatcc
    76801 agaaccatac gtaccatctt caaaaaactc ggaatattgg cactctggac aataataatg
    76861 aggggctaac ggattaactt cagtgattcc tgtcatcgtc gcaacaaagc tagagccaac
    76921 agagccacgt gaacctacta gatagccatc ttcattactt ttatgcacta gtttttgggc
    76981 gatcagataa ataaccgaga agccattacc attaatagaa ttcaactctt tttttaatcg
    77041 tttttgaatg atctcaggta acggatctcc gtacatttgt tttgcttttg tgtaactcaa
    77101 ttctgatatt tcatcttctg aacctggaat cttcggtgta taaagttcat ctttgactgg
    77161 aatcacttct tcgcagatat ctgcgatttt attcgtattt tctactacga tctctttcgc
    77221 tgtttcttcc cctaaaaagt gaaatgcagt tagcatctca tcggttgttc ggaaatggac
    77281 atccggcaaa ctatgacgat tcaacggatt cgctccgccc atagaattga tcaaaatttt
    77341 tcggtaaatg gcatcttctt cgttcagata atgtacatta cctgttgcaa caacgatttt
    77401 atccaaactt tttccgattt ctaccaaatt ttggataatt tcttccaaat catgttcatt
    77461 ttttaccaat tcttgctcga tcaaaggcgc atagaccgct tttggcataa cttcaatata
    77521 atcgtagaat tttgctcggt ttcttgcctc ttctacccct ttttgcatca tggcttcgaa
    77581 tatttctccc ttatcacaag ctgagccgat caatagattt tcacgcatct ttttcaattg
    77641 ggagcgtggt attcgtggga cgcgttcgaa gtattcgaca ttcgacattg aaatcagttt
    77701 gaacaaatct ttcagtcctg cctgattttt tgctaaaatc gttacatgga aaggtcgagc
    77761 ccttttgtaa gaatctcctt ctccgatatg ctcatttagc tgatcatgat aaagcatgtt
    77821 atgattgtcc attgcctctt tcacaaagat ccatgctaag tgaccagttg cttcagcatc
    77881 atagattgct cggtgatgct gttccaagct gacaccaaat tttttagata acacacctaa
    77941 tccgaaacgt ttgaattgag gatacagata tctagctaat tccaacgtat caatgactgg
    78001 attggccgct tcaggaatac cataccttgc gtagctagta ttcaagaacc ccatatcaaa
    78061 agccgcgttg tgggctacca aaattgtatc ttttgaaaat tcaaggaaca tccgcaatac
    78121 ttcttcttcc gactttgatc ctcgaaccat tccatccgtg ataccagtca gatctaccgt
    78181 tgttcgtgac aaaggatgtc ctggatcgat aaattcatca aagctttcga tcacatttcc
    78241 tttatacatt ttgactgcgg ctagctcgat gatcgtgtca tatactgcag acaatcctgt
    78301 cgtttccacg tcaaatacga catatgtggc ttcactcaat gcttcatgtg catcattata
    78361 agcaattggg acaccatcat ctacgacatt cgcttccacg ccgtataaga ttttcacacc
    78421 tgcttttttt ccagcactat gtgcttccgg aaaggcttgc gcaccaccgt ggtctgtaat
    78481 ggcgatagct cggtgtcccc atttccctgc ttgtgccaca agatcagaga tgctgtttgt
    78541 tgcatccatc gtactcatat tgctatgaac atgaagctct actcgttttt ccccttcagg
    78601 agcataatct ttgcgaggtg tatgtttgac ttctatgata tcttgcgcat tcatgaccaa
    78661 atcacggaca aacgtatctt cttgaatact tcctcgtacc tttaaccagc taccgacact
    78721 gatcgcatca aatacttgtt catctttttc gccgttcgag aattttttga cgataaatga
    78781 tgaagtataa tctgtgattt tcaaagtcaa gatcttgcgt tttgaacgta gttctctgac
    78841 ttctttgtcg aatacgtacc cctcaagtgt gactcttcgt tcttcttcaa cgatactgat
    78901 cattggtgtc gttggttcat cggctggaat atttcgtcct agctggatgt ggatgggtcc
    78961 ttcaagagct ggcgattgct cttttctttc ctttttcttt tgttcgtgga caactagact
    79021 ttcagctgct tgcttcataa aggcttctgc ctgttcttgt ttgcgttctt caaaaagttt
    79081 caatactcgt tccgcttgct gctcatccac ttctggttcg atacgaaatt ttgggaatcc
    79141 gtaactgacg aacaactctt ctactaatgg caagtattgt tgcttcaaat aagaaatagc
    79201 tcctgtactg tcgattggca agatgacttt acgatctttt atcacaggta cctgcgtttt
    79261 cagtacttgc tgtgctagtg gtgtatcgca ttgctgattt tccaaagctt gggcccagta
    79321 atcttgcaag agctgttcat cgaatgtctg gtcatctgct aagatattca gtttgacttg
    79381 tgcaatatct ttaaaagcga tagtcagatg ctgagtcaat gaccgatata gcataatagg
    79441 caaaattttg gaaaaatgca gcgtaaattc ccataaacgc gatttacgat ggaccactac
    79501 actatccatt tcaccagcag taagcagtgg atgatttttt tctgcttcct ctagttggat
    79561 ttgttccaac agtttttcaa ataaatctcg tttttctgac aaagatatac gccctttctg
    79621 atgagaaaca atgcaattga tcgcatctta tcctcttctt tttcagtacc ttttagtata
    79681 ctcgtttttt ctgagtttta cattaaaaaa ttggaactgc gattcaaatc gcagttccaa
    79741 ttttaaaagc gaatcatcag attgtcaaaa acagctgatt cagctatttt tattttctgt
    79801 gttttaacgc ttattattcg ccttggttca agaggattgg taaagtattc accaattctt
    79861 ctttacgtac ttcaaccatt tcgccagttt tcttgatttt cacttctacg attccatcca
    79921 ctgctttttt accgacagtg attctgattg gacagccaat caaatcagaa tccgcgaatt
    79981 tcactcctgc gcgttcattt ctgtcatcaa ccagtacttc atagccagct tttgtcatcg
    80041 cttcttctag ttcattcgtc aggtttgttt ggtattcgtc ttttagattc atttggacga
    80101 tatgcaaatc aaatggcgca attccttttg gccagttgat tccttgttca tctgaatgtt
    80161 gttctacgat tgctgataat aaacgactta caccgatacc ataacagccc ataatcacaa
    80221 atttttctcg tccattttcg tctagtacag ttgctcccat agattcactg taacgagtgc
    80281 cgattttgaa gatatgtccg atttcgattc ctcgagtaaa ggcaagaaca ccattgttgt
    80341 ctggtgaagg atctccttct tgtacaaaac gaagatcttc ataagaaagt acagtgaaat
    80401 cgcgttctgg attcacattt ttatagtgga atcctgtttc gttcgctcca gtaatggcat
    80461 tcgctaaatc ttggacataa cggtctgcat atacttttac gtcatctgaa acaccgactg
    80521 gtccgacaga accaaactca gcacctagat atttttgtgc ttcttcttct gttgcttctt
    80581 ctaaaaagtc agcagataaa aagtttttca gttttacgtc attgacttca tggtctccgc
    80641 gtaccaaaac aaggacaggt tgttcatccg caatgaacaa tacagacttg atgatttttt
    80701 gaggttcaac agaaaagaaa tctgctactt cgtcaattga ttttacgtta ggtgtagcta
    80761 ctttctccaa ttcaagctgt gtttcatgcg atttttttga tacatagtag cttgtagcca
    80821 tctccaagtt tgcagcataa tcactttcag tcgaataaca gatcgtatcc tccccgattt
    80881 ctgagatcgc catgaattct tttgagtctt tcccgcccat tgcgccaccg tctccgataa
    80941 tcgagcgaaa ttctaagcca caacgcttga atacttcggt gtaggctttt tcgtaatctt
    81001 tatatgtctc gtccaaactt tcttccgttg catggaaaga atacgcatct ttcatgataa
    81061 actctcttcc gcgaagcaaa ccgaagcgag gtcgtttttc gtcacgatat ttaggttgga
    81121 tttgataaag atttaaaggt aatttcttat atgaattgat ttcattacgc atcaaatcag
    81181 taaaagtttc ttcgtgagtt ggtccaagga tcatttttcg atcattgcgg tctttgaaac
    81241 gatacaagtt tggtccatat gtttcgtaac gcccggattc ttcccaaagt tctgctggca
    81301 agatggcagg catcagcatt tctaccgctc cgattttttc aaattcttcc cgcataatgc
    81361 gtttcagttt ttccaataca cgatttgcta atggcagata tgaataaata cccgctgata
    81421 cttggcggat atatccagct cttagcaaga tttgatggct taatacttct gcatcatttg
    81481 gaacttcgcg taatgttgga atcaacattt ttgattgtct cattctatat actcctttat
    81541 ttcctcaaaa tagttatcgt ttgttattat accctatttg tcaacttttt ctagaaaaag
    81601 aatcgttgaa tatcgttcca tgtaactagc accatcaaca acattaaaaa tccaaagcca
    81661 gctaatgtca atattccttc tttttcttga cttaatggtt tcccgcgaat cccttcaaaa
    81721 atattcaaga ctaatttccc gccatctaag gcaggaatcg gaagcagatt gacgattccg
    81781 agattcattg aaagaagcgc catcaaacta ataacagttg ttacaccttg atttgctgct
    81841 tctgaagaca attggtacat catgacaggt ccgcctaatt tatctaaact gaaacctgta
    81901 aatagtgatc ctaaggcttt gaaaatttcc aatgaaccgc tgaaagcttg acgcgtccct
    81961 ccaatgatct tatccataaa acctgtattc attggggctt ttataccaag ttggccaact
    82021 ttttcgccat ttgactctac agatttcggt gtcacgtcga cagattgcac ctgaccttct
    82081 cgttcgatct taaagtctaa tgttttatcc ggatttttcg taatgactgt tgtcagatca
    82141 ttccatgaat ggatttcttt tccgtccaca ctgactacct catcattttc ttttaagcct
    82201 gcttctgccg cagctccatt aggcatgatc tctcctacgc gattagtgtt cgtcacttga
    82261 acaccacctt gcataaatgc cagaatgatg aataacagga ttgccaaaat aaagttattc
    82321 atgggtccag caaagttggt cagcatacgc tgccacaatt tagccgattg gaactgtacg
    82381 tcttttggcg caattctgat ttctgttccg tcgttttcaa taatcgtcgc atcgtgatca
    82441 acagggtagg ttactacttc tgtttcgtct ccattcacat aaccagtgat agtcagctca
    82501 tcttctaaat cataacggct caattccatc gggatagcat ttgtcaattg gattttctta
    82561 cttaaattta tcttctctac gatgccgtca gaatttagta aaagagaaag aggcattcct
    82621 ggtgccattt ctgtttcatc atccccattg cctgccattc gaacataacc gccaataggt
    82681 aataggcgaa gcgtatatgt tgtcccgtct tttgcttgat gcccataaat tttcggaccc
    82741 ataccgatag caaattcgcg aacgaggatt cctgatcgtt tcgcaaagaa gaaatgacca
    82801 aactcatgaa caatcactaa tataccaaaa acgatgataa atgtcagaat cgttttcata
    82861 gcttttttct cctttacttg ttttttgtgt tttttataaa acaacgataa aacactataa
    82921 ttttaccata gtataccaaa gacaccaata gtatcaatat aatgaaaaat aaaaacctgc
    82981 gtcttttatg aaattcacaa agaaacgcag gtatacttac taaataatgc caaataaatg
    83041 catgatagga aatacaaaca gcaaactgtc gaaacggtct aagattccac catggcctgg
    83101 taagatattt cccgagtctt tcacatcata atgacgtttg attgcagatt cgaccaaatc
    83161 accaaattgt ccgactgctg aaaaaataat cgtcatcaga agcatgacaa acataccatg
    83221 attaaatagt tcttttgctg ggtatagcaa taaataaaga aatgcgacta caacagcact
    83281 accaatacca ccgagcgcac cttcaatcgt tttgttgggc gaaatatcag gacttaactt
    83341 atgctgacca taacgtcgac caaccatata tgctccgata tcagttgccc aaacaataaa
    83401 tagaccaaat atcaaaacag ccaagctttc tgttcgtgca ttgacaaaat tctggaaacc
    83461 tattcccaca tacaagctga caagcacagg aaaacctgct tcatcaatcg tatacgtatt
    83521 tttagaaata actgatgttc ctaaaagaat cataactata agataaaata acataaatgt
    83581 acttacattc tctggaagaa agaaaaacca tctttctttt ggcaaaacaa gtaacactgc
    83641 accaacggcg gataaaactc cttcaaaact taagagtgtc aatcctttca tccgaaacag
    83701 ctcgtaaact cctattactg ctaagattgc tgctgtaagc tcaaccgcta tgcctccgat
    83761 ccatataatc ggaataaaca agactagcgc cacggctgct gtgaccacac gttgtttcat
    83821 gactgatccc ctttctcatc ttctgttttt tttacaccgc cgaatcgacg gtctcgattt
    83881 tgataagagg cgattgcttc ttcaagatgc gcaccatcaa aatcaggcca aagcgctttt
    83941 gtaaaataca gctcactata tgcgatctgc cataacagaa aattactaat tcgctcttct
    84001 ccacttgtac ggatcatcag ctcaggatct tgtaactctt taggcaagaa acctgtcatt
    84061 aaatgcttag caatcaattc atcatcgatt tcttctgcgt gtatttctcc ttttgctact
    84121 tcttcggcaa tttcttggac agcagtcacg atctctgctc tgcttccata attcaaagca
    84181 aaattcaata ccattccagt attgtttttt gtttgctcaa ttgcacgtct tacagcatct
    84241 tgcgtatgtt ctggcaatac gttttcataa cccatgacat gaactttgac attttcttta
    84301 atcaattctg gtacgaacgt atcaaagaag tcgacaggta gttgcatgag aaaacttact
    84361 tcatcttttg gtcgcttcca gttttcagtc gaaaaggcat aaagcgtcaa cactttcact
    84421 ccaagccttg atgctttttt tgtgactttc tttactgttt ccatgccttc tttatggcca
    84481 gcaactcgtg gcaaacgacg gttttgcgcc caacgaccat tgccgtccat gatgatggca
    84541 atgtgctgag gaattggtcc atcggtatta aattgaaatt cgcttttttc ttgaatatat
    84601 ttgttttttt gcggaaaaaa acgtaacatt ctttttcctc ctatacttaa
//
LOCUS       DAZUJR010000003        64952 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.003, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000003 DAZUJR010000000
VERSION     DAZUJR010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 64952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64952
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.003"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(61..726)
                     /locus_tag="ACG804_000170"
     CDS             complement(61..726)
                     /locus_tag="ACG804_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HFS4831135.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(873..1478)
                     /gene="dhaL"
                     /locus_tag="ACG804_000171"
     CDS             complement(873..1478)
                     /gene="dhaL"
                     /locus_tag="ACG804_000171"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaL"
                     /protein_id="HFS4831136.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(1506..2516)
                     /gene="dhaK"
                     /locus_tag="ACG804_000172"
     CDS             complement(1506..2516)
                     /gene="dhaK"
                     /locus_tag="ACG804_000172"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004371 - glycerone kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HFS4831137.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(2491..2886)
                     /gene="dhaM"
                     /locus_tag="ACG804_000173"
     CDS             complement(2491..2886)
                     /gene="dhaM"
                     /locus_tag="ACG804_000173"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="HFS4831138.1"
                     /translation="MKKSILLISHSQKVTDGIKEMIEQMQKSEEVQIFSLGGINGEIG
                     SDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEEEQQQRYHLVDAPLVEGA
                     FAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            3040..3360
                     /locus_tag="ACG804_000174"
     CDS             3040..3360
                     /locus_tag="ACG804_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HFS4831139.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(3472..4329)
                     /locus_tag="ACG804_000175"
     CDS             complement(3472..4329)
                     /locus_tag="ACG804_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFS4831140.1"
                     /translation="MKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTISSSG
                     AENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELEEALE
                     AAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQQAKE
                     FNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAASFQRI
                     KDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGVLVAA
                     AYGIIRKKK"
     gene            complement(4437..5741)
                     /locus_tag="ACG804_000176"
     CDS             complement(4437..5741)
                     /locus_tag="ACG804_000176"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFS4831141.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(5738..6247)
                     /locus_tag="ACG804_000177"
     CDS             complement(5738..6247)
                     /locus_tag="ACG804_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831142.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(6422..8557)
                     /locus_tag="ACG804_000178"
     CDS             complement(6422..8557)
                     /locus_tag="ACG804_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HFS4831143.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(8640..10295)
                     /locus_tag="ACG804_000179"
     CDS             complement(8640..10295)
                     /locus_tag="ACG804_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFS4831144.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(10297..10611)
                     /locus_tag="ACG804_000180"
     CDS             complement(10297..10611)
                     /locus_tag="ACG804_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFS4831145.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            10781..11041
                     /locus_tag="ACG804_000181"
     CDS             10781..11041
                     /locus_tag="ACG804_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HFS4831146.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            11055..11369
                     /locus_tag="ACG804_000182"
     CDS             11055..11369
                     /locus_tag="ACG804_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HFS4831147.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(12099..12653)
                     /locus_tag="ACG804_000183"
     CDS             complement(12099..12653)
                     /locus_tag="ACG804_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HFS4831148.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(12779..14708)
                     /locus_tag="ACG804_000184"
                     /pseudo
     CDS             complement(12779..14708)
                     /locus_tag="ACG804_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(15014..15730)
                     /locus_tag="ACG804_000185"
     CDS             complement(15014..15730)
                     /locus_tag="ACG804_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HFS4831149.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(15731..17554)
                     /gene="glpO"
                     /locus_tag="ACG804_000186"
     CDS             complement(15731..17554)
                     /gene="glpO"
                     /locus_tag="ACG804_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HFS4831150.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(17568..19064)
                     /gene="glpK"
                     /locus_tag="ACG804_000187"
     CDS             complement(17568..19064)
                     /gene="glpK"
                     /locus_tag="ACG804_000187"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HFS4831151.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(19200..20660)
                     /locus_tag="ACG804_000188"
     CDS             complement(19200..20660)
                     /locus_tag="ACG804_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4831152.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(20650..21945)
                     /locus_tag="ACG804_000189"
     CDS             complement(20650..21945)
                     /locus_tag="ACG804_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFS4831153.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(22277..22954)
                     /locus_tag="ACG804_000190"
     CDS             complement(22277..22954)
                     /locus_tag="ACG804_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HFS4831154.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(22984..24075)
                     /locus_tag="ACG804_000191"
     CDS             complement(22984..24075)
                     /locus_tag="ACG804_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HFS4831155.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(24176..24610)
                     /locus_tag="ACG804_000192"
     CDS             complement(24176..24610)
                     /locus_tag="ACG804_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFS4831156.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(25194..26651)
                     /locus_tag="ACG804_000193"
     CDS             complement(25194..26651)
                     /locus_tag="ACG804_000193"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFS4831157.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(26648..28543)
                     /locus_tag="ACG804_000194"
     CDS             complement(26648..28543)
                     /locus_tag="ACG804_000194"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFS4831158.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(28601..30376)
                     /locus_tag="ACG804_000195"
     CDS             complement(28601..30376)
                     /locus_tag="ACG804_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFS4831159.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(30426..31922)
                     /locus_tag="ACG804_000196"
     CDS             complement(30426..31922)
                     /locus_tag="ACG804_000196"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFS4831160.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(32116..33738)
                     /locus_tag="ACG804_000197"
     CDS             complement(32116..33738)
                     /locus_tag="ACG804_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFS4831161.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(34066..35379)
                     /locus_tag="ACG804_000198"
     CDS             complement(34066..35379)
                     /locus_tag="ACG804_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFS4831162.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(35624..35848)
                     /locus_tag="ACG804_000199"
     CDS             complement(35624..35848)
                     /locus_tag="ACG804_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831163.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(35868..36290)
                     /locus_tag="ACG804_000200"
     CDS             complement(35868..36290)
                     /locus_tag="ACG804_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFS4831164.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(36432..37142)
                     /locus_tag="ACG804_000201"
     CDS             complement(36432..37142)
                     /locus_tag="ACG804_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase beta subunit-related
                     protein"
                     /protein_id="HFS4831165.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(37160..37657)
                     /locus_tag="ACG804_000202"
     CDS             complement(37160..37657)
                     /locus_tag="ACG804_000202"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4831166.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(37694..38146)
                     /locus_tag="ACG804_000203"
     CDS             complement(37694..38146)
                     /locus_tag="ACG804_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFS4831167.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(38281..38886)
                     /locus_tag="ACG804_000204"
     CDS             complement(38281..38886)
                     /locus_tag="ACG804_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFS4831168.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(39336..39956)
                     /locus_tag="ACG804_000205"
     CDS             complement(39336..39956)
                     /locus_tag="ACG804_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFS4831169.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(39958..40827)
                     /locus_tag="ACG804_000206"
     CDS             complement(39958..40827)
                     /locus_tag="ACG804_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HFS4831170.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(40850..41257)
                     /locus_tag="ACG804_000207"
     CDS             complement(40850..41257)
                     /locus_tag="ACG804_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFS4831171.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(41276..42565)
                     /locus_tag="ACG804_000208"
     CDS             complement(41276..42565)
                     /locus_tag="ACG804_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFS4831172.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(42592..42894)
                     /locus_tag="ACG804_000209"
     CDS             complement(42592..42894)
                     /locus_tag="ACG804_000209"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFS4831173.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(42919..45012)
                     /locus_tag="ACG804_000210"
     CDS             complement(42919..45012)
                     /locus_tag="ACG804_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFS4831174.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(45501..46265)
                     /locus_tag="ACG804_000211"
     CDS             complement(45501..46265)
                     /locus_tag="ACG804_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HFS4831175.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(46376..47245)
                     /gene="mdcB"
                     /locus_tag="ACG804_000212"
     CDS             complement(46376..47245)
                     /gene="mdcB"
                     /locus_tag="ACG804_000212"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046917 - triphosphoribosyl-dephospho-CoA
                     synthase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0019361 -
                     2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HFS4831176.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(47270..48346)
                     /locus_tag="ACG804_000213"
     CDS             complement(47270..48346)
                     /locus_tag="ACG804_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFS4831177.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(48370..48963)
                     /locus_tag="ACG804_000214"
     CDS             complement(48370..48963)
                     /locus_tag="ACG804_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HFS4831178.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(48967..50643)
                     /gene="mdcD"
                     /locus_tag="ACG804_000215"
     CDS             complement(48967..50643)
                     /gene="mdcD"
                     /locus_tag="ACG804_000215"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HFS4831179.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(50633..50932)
                     /locus_tag="ACG804_000216"
     CDS             complement(50633..50932)
                     /locus_tag="ACG804_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HFS4831180.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(51034..52680)
                     /gene="mdcA"
                     /locus_tag="ACG804_000217"
     CDS             complement(51034..52680)
                     /gene="mdcA"
                     /locus_tag="ACG804_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015451 - decarboxylation-driven active
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HFS4831181.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(52687..53598)
                     /locus_tag="ACG804_000218"
     CDS             complement(52687..53598)
                     /locus_tag="ACG804_000218"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HFS4831182.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            53718..54575
                     /locus_tag="ACG804_000219"
     CDS             53718..54575
                     /locus_tag="ACG804_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFS4831183.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(54762..55124)
                     /locus_tag="ACG804_000220"
     CDS             complement(54762..55124)
                     /locus_tag="ACG804_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HFS4831184.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            complement(55313..55495)
                     /locus_tag="ACG804_000221"
     CDS             complement(55313..55495)
                     /locus_tag="ACG804_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831185.1"
                     /translation="MIFFISEYINQTPFYSKNTEKINGGQVSTDFSIIVYFSGAFTDD
                     KNFIMNLKNDTTKIKK"
     gene            55470..56909
                     /locus_tag="ACG804_000222"
     CDS             55470..56909
                     /locus_tag="ACG804_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4831186.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(56916..59468)
                     /locus_tag="ACG804_000223"
     CDS             complement(56916..59468)
                     /locus_tag="ACG804_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HFS4831187.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(59582..60913)
                     /locus_tag="ACG804_000224"
     CDS             complement(59582..60913)
                     /locus_tag="ACG804_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFS4831188.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(60879..62357)
                     /locus_tag="ACG804_000225"
     CDS             complement(60879..62357)
                     /locus_tag="ACG804_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFS4831189.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(62662..64497)
                     /gene="tdc"
                     /locus_tag="ACG804_000226"
     CDS             complement(62662..64497)
                     /gene="tdc"
                     /locus_tag="ACG804_000226"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HFS4831190.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
BASE COUNT        18529 a        13911 c        10994 g        21518 t
ORIGIN      
        1 aaaccttcac tcgcaagccg agagtaaggt ttgtttttcg cattgcttat ttcgtgttgt
       61 ctattgaaat ttttccgcac ctagcttttg atatagtggt gctagttctt gtaaggtttc
      121 agcggttatt tgctcaacgt gttcgatttc ttgcggatag aagaatagtt tacccatttg
      181 aaaggttcgg tctctcatcg cttttttcaa ctcttcttgt ttctttgtat cggacaaata
      241 gtcagacaaa gctaagtggt cgtcaagttc atgttctggt tgcggccata tgtaataatc
      301 cttgatatcg actgttttgc tccactcttt cagtatcgca agcaactggt tatacgctgc
      361 aatgctacca tatcgttctt cgcttttata atgttggtac atcaaataga tttggtattg
      421 tttttgattc aacaaaactg ctagacaggc attctcgtct tgacgagatt cgcttcggta
      481 cgcgctccaa aaatgactgc gtaaattcca gccattcgtc cagctttcga ttttaggttt
      541 gctcatgccg tacatatcag gcaaaagtgc agctgtctgg agctgaatct ctttccattt
      601 ttgccagtgt tctttatatt ctttcttgat ttgttcaatc ttatctgttg gatggctctc
      661 tttgagctgt ttgaatgcgt agattggtcg atcaaacaac tgataatctg attttccaag
      721 ttccattgtt tcgcctcttt ccgttatctt ttgtattcta cctgaatttt gcgatatgga
      781 caaatagagg ttgtgaaaaa gctgttctgc atcaagtcat aagaacagcc aaacaaaaaa
      841 ctgcgatgag catcaccgca gttttattga acttaaggtt gattgatcac atctaaaagc
      901 gttgaaaata aaatggcact agaagcagct cctgggtcga tatgtccgat tgcacgctct
      961 cctagatagg aagctcgtcc ttttttagct accaagactt tggtgtgttc ttttgcctgg
     1021 tcaatgattt cttttgttaa attccctgcc ttcaatgcct ctgtgactgg cagccaaaca
     1081 tctaacatcg ttttatcgtc agcttctgcc tttcctcggc tttgaatacc cgctgttccc
     1141 tgctcgatca cttcgcctaa tttttcttga gaatcaatag aatcgacctc ttttgtcgct
     1201 ttcatcatgt tcatgaatgc agatccgtat aacggaccag aagccccacc gactttcgat
     1261 atcatcgcca tagagaatac tttgaatgta tcgctgattg tttcaggatg atcggcttga
     1321 aaagcttctt cataagctga aacccctctt cccatgttat ttccatggtc tccatcgcca
     1381 atcggggtat ctagatcact gagatattgt ttgttctgat tgattgcctc tgcaaattgc
     1441 gtgagccatt cttggatttc ttgaacggtt agtttcatat tatcaccctt ttatcttgag
     1501 attttttacc atgaaatcgt ctgtacattg ctttctaaag aatctttcca ttgtgtctcc
     1561 gtcaagtcga tcagtgttag agaaagacct tgcatatcta gtgaggtcat aaaattaccg
     1621 acttttcgga aaactacatt gacgcctctt tcttccaaca gagctaaaac atcattcatg
     1681 aacacgaact gttccatcaa aggcgtcccg cccattccgt tgactagtac acctgcttct
     1741 tttggtaaat tcgagtaatc atctaaaatc ttagtaacaa gttcctttgc cagtacttta
     1801 gaaggctgca tcttttctcg acgatagcct ggctcaccgt ggataccaac accatactcg
     1861 atctcatctt ctcctagttc gaatcctggt ttccctactt ctggtacagt tgctgctcga
     1921 agcgctagac cgatcgtctt agttgcctgt acgacctttt ctcccagttc tttcaactca
     1981 gctagggaag caccgtttct tgctgcatcg cccacgattt tgtgtacaag gacagtacct
     2041 gcaactccgc gttttccagc agtatacgta ctattttcaa cggcgatatc atcatctacg
     2101 atcacacttt ctacttcaat atcgtccata gcagctaatt cctttgccat atcgaagttc
     2161 aatgcatccc ctgtataatt cttaacgatc agcaaaactc cttttccact atcggcttcc
     2221 ttaatagccg tctgaatctg atctggagtt ggagaagtaa acacatcacc aagcaccgct
     2281 gcacttaaca tcccttcccc tacaaacccg gcatgggatg gttcatgtcc gcttcctcca
     2341 ccagaaacca aaccaacttg ttccgctttc tgattcttgg ctacaacacg ggaagattct
     2401 acacgatgaa caagttctgg atagcttttt actaatcctt ccagcatttc ttcgacaata
     2461 ttgcttggat cattcatgat ttttttcaat ttattcccat cctttctttc cggcattttg
     2521 tgcttctgtt aagatttgct gagtatcatc tgttataccg gcagtgatgg ctgctgcaaa
     2581 agctccttcc actaaaggcg catccaccag atgataacgt tgctgctgct cttcttccaa
     2641 catgtctttt gccagttccg agttcaatac cgcgctaccg atatccgcaa aaacaaaata
     2701 actagctgca tcgcttgatt cattgactgc ttctacgatt ttcatcgggt ctgatccgat
     2761 ctcgccattt attccgccga gagaaaaaat ttgcacctct tcggattttt gcatctgctc
     2821 aatcatttct ttaataccat ctgttacttt ttgactatga gaaataagca aaatactttt
     2881 tttcacaaga atcttccttt cttttacata gttgctaacg attggtttcg ctttcattaa
     2941 tgaacaattc aagtatataa taaatttcta attttgggaa aatatgtgta gtgcttcttg
     3001 aagtttgtta tactttaatt aaaagagagg agtgatcgaa tgattacaac aacaacgaac
     3061 agtgtagagg gaaaagccgt agtagcttat aaagggatcg tttttggtga ggtcattact
     3121 gggatccatg catttaaaga cttggaggcg gggttgcgaa atatctttgg cggccgctca
     3181 aaaagctatg aaaacgaact aatgggtgca agagaagaag cacttgccga aatggccgaa
     3241 cgtgcaaaag cattaggagc tgatgcgatc attggcgtaa aaatggacta tgaagtatta
     3301 ggcagcgaca atggcatgct gatggtcaca tgtagtggaa cagctgtctc cacgagataa
     3361 gtaggggaca tctgttttaa taactaaaga gagatgggac atgtagtggc actcaagaat
     3421 tagatttttc agtctaactt cgaggtactc taccttccca tcctctcttt tttatttctt
     3481 tttgcggatg attccgtaag ctgctgcgac taacacaccc gcccctgcta aggaataact
     3541 gacagaagct gttttttcat ttgtttttgg caaagtctga cttgttgatt tggatggctc
     3601 tgtcgtttgc tgaactgttt ctgtcgtgct tccagaggtc actgattttt ctcctgccga
     3661 atgcaaaata tcttttattc gttggaaact agctgctaag tcagcttttt ttgcttcaaa
     3721 atcattagca actgtttgtg cttcgctgat ctttccgtgg attgcttgac tggccgctgt
     3781 gatatccgct tgagtttgac ttagctttcc agaagctgtt tgagcaacct gatttaattg
     3841 ctgattgaat tcttttgctt gttggatctt cccgtcaaga tctgtttgga cagcttccgc
     3901 ttttgctttc gcttcggcaa gctttttctc aagttgtgca cggtcatttc ccactttatt
     3961 tttaagatca gctaaatctt gatcgattgc tgcttggtct tctttcaatt tgttttttgc
     4021 agcttctaat gcttcttcga gttcttttct tttattttcc aagtcttgca aatgatcgat
     4081 ttggtcagaa gaggtagaac tatttattga tgtatcttct gaagatgaaa tcgtttctcc
     4141 tgaattatct gtcggtacat tggaagtcat ttctgtttcc gaggcaccgt tttcagcacc
     4201 agaagagctt atggttgttg aaggttctgt ttgagcaggt tcagaagttt ccgcaaaagc
     4261 tgtctgtccc aataagaaaa tactggaaac agcaattggc cagattaacg gcttcattct
     4321 ttttttcatc acttttccca tccttactac tttttaacta atttcttatt ataagcaaaa
     4381 atgtttggaa gaaccataaa cacaacaggc tgtttgtcta aaaaacggtg catcttttat
     4441 ttttttgtac gttccgggct tttccatgtc ccgcttccat aacctaaaat cgttttgact
     4501 gctggaatga aagtcgtcac gatcgttatc gcgttcacta tccagaacaa aagcatatat
     4561 agtggtgcga aaagaaggta tttcaatttt cttcgtcgat catctacaat cagcgaagct
     4621 agcaactgga aaaatcctgc gaccatttca aagcagatga acacaaaact gaatgtaaaa
     4681 gtaatataaa tctgttcgta gtttccttga tatacataat gcccgattaa tccagcaaaa
     4741 agaactacgg aaatacaaaa gaatattgac cagacaatac tcaatgtttg atcaatgaag
     4801 atgatcgttc ttccaatatg tttaaaagga tggagcatca cttttttgaa attcgtcagc
     4861 cagacttctg ttccaccttt tgcccaacgt tttctgtgtc gatatagcat cttcaacgtc
     4921 acaggtactt ccatgaaaaa gataatctca ggagcaaaaa cagataacca gtcatttaac
     4981 tgatgatccc aagcaatact gatgtcttct gtcgctcgat cttgtctgaa tccgcccaca
     5041 tcgatcaagg cttcttttcg atacatcgta tttgctccac tgtacgcata aagaccaccg
     5101 aaaacagctg actgtgttcg tttaatgatg cccacgatac ttgagaattc aaccgtttga
     5161 gattttgcaa tcaatttggt acgattttgg acatccatat ttgcagtgac cgcagcaata
     5221 tgtcttgcac cagggcgaat gaaataattc acatacctaa tcagtgcatc tggctccggt
     5281 accgtgtctg catcattgct taaaatcaat ttcccttttg caaaggcaag tccgatatta
     5341 aacgcgtggg cttttccttt atttttttcg atccgaacca cacgaagatt agcgtatttt
     5401 ttcatcagtc tagctaatat ttctggtgtt tggtccgttg aaccatcgtc tgtcactaat
     5461 acctcatagt tgtgataatt caatttcgtc atcaaatact cgattgtata ttcgatcaca
     5521 atttcttcat tatgggctgg caccatgatc gtgatgaacg gttcgacact caagggaaca
     5581 tctacccatt ctttttgctt atgtttgtat aaaaacacat aacaccagac accaataaac
     5641 catacaaatc cgcctaaaat cggataagaa acgagaaaaa aatacataat agacaaacaa
     5701 gtatctaaga ataaattacc tgtatgggtg attgagatca tttcagttcc accccatttt
     5761 ctttatacaa atctgcaatg aatgtcgtat ctagattttt ctcttcggag acagaataaa
     5821 aacggaccgt ttctctctct tcttttgttc caaaacgttc cgtatacact tcttcaagta
     5881 attcttgtct ttttttcaat ttttcatctt catattcaaa agatttattt acttttttgt
     5941 atagatttcg attgttccac ctagtcaata caaatgaggt aatcaggaaa ctgaaaaaaa
     6001 tcaatacaaa aaagccgatt aagaaataca gcattttctt ttctgataaa aaagcgtaca
     6061 aggaaaaatc cttggctctt tctggtctcg ttaatgggaa aaagacccat ataaaaggaa
     6121 gaacaacgat catccatcct aaaagagcca ctaacgtttg ccaaatcttt aaccagtaat
     6181 taccttttga aaaatactta tctttcacca aaattgatgc aacttcttct cttgttactt
     6241 ttttcatatc ctcacctcac gtttttttgt tacgacgtag gagtttacca tacatttcat
     6301 ttcttttcac ataaagtgtt cctaaatttt tcctaagaaa aagaacaaaa catttctcat
     6361 cagcaaatga aaaatatttt gttcttttta tcagttgttc tttttatttt ttatctctta
     6421 attatgttgc tctttccaat acgacaatgc ttttcattcc tctagatatc gccgtgtaca
     6481 tttgtctgcg tcttctttgc tcatctccat cgttttcaaa tggatataag attacatgat
     6541 caaattccag tccttttgct agactcaaag gaatgatttg gcagttttct aatccatatg
     6601 aatttttttt aatcgattct tgtagcgttt gggtttcctc ttctgtttgg gtgataactg
     6661 ccgctttttc tccttttaga gaaaccaaaa tctcagctag tattttcaac aattcttcag
     6721 aggatcgaaa agagcggtat tcgggttctt ttccttgcgg tcggatcgat acgatgtcga
     6781 tcttctcttg atccacagca taggttttga aaagctctgt gattgctccg ctagaacggt
     6841 aactatttct aagatcatac cgatggatcg gcagatggta gtcgtcgaaa caacgcataa
     6901 tatcagcaaa agtagtggaa gaattaaaga ttgcctgatt ctcgtcacct actaaagtaa
     6961 agtgagtttt tggaaataat tcgatcaata gacctaattg tgccagggta taatcttgta
     7021 cttcatcaat caatagatag cgaaatgctg gtacatttac cttttcaaca agtaaatgac
     7081 gaatagctaa tataatgact gcttcatcaa cagtacgtgt gggttgccaa gcataagctg
     7141 agccatatcg tttttcataa attctttcaa acaactgatg ctcatccacc catgccattt
     7201 cttcgatttg tctggttatt tttcgatatt ttttttgtaa aagtttcctt gcataagcta
     7261 caatactttg ttccgaatca tcagaaatca atttaccgaa taattccaac tgcctatctt
     7321 ctgtcaacga gagtacctga ttctgcacag caggactttt tgcttgtttc aaaagatgat
     7381 tcttccattc gctcatcagt gcctttttcg ttgcttgaag cctatcgatc aatttaggat
     7441 gagcaggaac tttctcatat attttttcga tcgttttttt agaaaggact gtttttccat
     7501 ttttagtaag tccacggata aaattcggat gatctaaaaa caaaggatct gattgtttta
     7561 gattatcgat aaactttttg ctacgcaaac gttctgtctg ctccgataca ttttctcccg
     7621 tgatacgttt gaaataagcc tcttcacctt ctatttcctc tgctgaaagc tgtgaaacca
     7681 gctgtatgat ggttagattc agtggatttc tttcacctaa tgatggtagg acattcgaaa
     7741 tatagtcgat aaaccgatga ttaggtgata gaatcagcaa gtcatcggat gtcatcgtat
     7801 ctcgatataa atagagcaga tacgcaatac gctgcatgat agcagaggtt ttaccacttc
     7861 ctgctacgcc atttaccaag atattttgac ttttcacatc ccgaatgatt gtgttttgtt
     7921 ccgattggat cgtagcagtg atagccttca tttcattggt ctcatcttgg cctaagactt
     7981 ctaataatac gtcatcttga atagctacag acgtatcaaa aaacttgacc aaacgatctc
     8041 tttccaaaag aaattgtcgt ctttctttaa taaccgtatc gattttattt tgacgaaccg
     8101 tataagaaga tggaccaatc atgttattgt aaaaaagttc ggcaattggt gaacgccaat
     8161 cataaacaag attttcatct gcatcatctg tgaaatttgc tgtaccgata taaaaggatt
     8221 cttttggctc attatccaga aagtctacaa cgacttttcc aaagtaggga cttttcaata
     8281 aacgttcgat ctttgctagc tgattttctg cgtttttctg tttgatattc atctgatcga
     8341 tttctctatt tttcatttca atcatcgaaa aagtatccag gttatctaag taactgtcaa
     8401 aattcaatcg aagctcgcca gccatttctt tcaacgactg gtttccttct atttttgccg
     8461 tatccatcga ttcccgcagt tcgttttttt tatcaattag cttttgatac acgttcttca
     8521 gatatgcttc ttctaactgt ttttgtgtgt tgaccataca cattctcctc tttttttaaa
     8581 gtggtggaac cgattagttt acctctttta agagtcgaat gcaagctttt taacgagtat
     8641 catttgttag gatatatcag ttcttcaggt cggacagttt gatataaaga aaatgcacca
     8701 tcaaggtttt ttacgtggta gccagactgc ttcaagattc tttccgctag atagctacgt
     8761 aatccgctat gacagctgac gatatattct tgttggctgt ctaattcatt taatcggtcc
     8821 cgaagttcat tcaaagggat atgtttggct tccttgaatt tgcccttttc caattcttct
     8881 gctgttcgca catctaataa aatttttcct tttgctagtt ctgtcggcaa ttcatgccat
     8941 tgtacggttt cactaagccc ttctgcaatg ttcattgctg catatcctag catgtttact
     9001 ggatctttgg ctgagccaaa tggcggtgca tacgtcaatt ctaattccgg taaatcgaag
     9061 atcgtcaaat gccctttgat tgctgttgct aaaatatcga tccgtttatc cacacctttt
     9121 gccccaacac cttgtgcacc ataaatctcg ccagtctctg gatggaagat caacttcagt
     9181 aaaatatctg ttgcttctgg ataatagctt gcatgatctt ttcctgatac atgaatgact
     9241 tcaaaagaca gttcgttttc tttggctgtt ctttcactta aaccggtgga tgcggcagtc
     9301 attccaaacg ttcgtataat tgctgttcca ataccgcctt gatttcttcg agaaattccg
     9361 gaaatcgtgt ccgcaacttg tctaccttga cgattggctg gtgaagcaag agaaataagt
     9421 gcatcttttc cagtgatttg ctgttttaca acgatagcat cccccaccgc ataaatatca
     9481 ggaatattcg tttgataacg ttcgtctact aggatacccc cgcgtatgcc taattcgatt
     9541 ccagcggtca ctgctagctg gttatcagga cgaacaccaa tggataaaat aactaaatca
     9601 gcagggatgg tacgcccatc atccagtcgc aatcgtttcc cgtggtcttc aaatccagcg
     9661 acagcatgag aagtaatcac ttctactcct tgatgagaca attctttttc tataaaagct
     9721 gccatttctt catccagtgt tggaagaata tgtggtgctt gttcgatcac catgacttct
     9781 aaacctcttc tttttaggtt ttctgccatt tccaatccga tgaatcctgc accaacgatc
     9841 acggcacgct ttggctgttt ttctaatgca tgcatcactt tatcgatatc tggtacattt
     9901 ctaatagaaa aaacattgtc ggcttctgtt atccctggaa tcgatggaac aactggtttt
     9961 gcaccaggag ataaaaccaa tgcatcgtac tgttcaatgt gtttttgacc ctcatgtacg
    10021 acttctaccg ttttgttttc gggaaagatg gctgtcactt catgatttgg acgcacatct
    10081 aaacaaaaac gagcggataa tgattctggc gtttggacaa gaagattttc ccgttcactg
    10141 atttctcccg aaagataata aggcaagccg caatttgcaa aagaaacata cggtcctttt
    10201 tcaaaaacaa cgatttctgc atcttccatt aatcggcgaa gccgtgtagc agcagacatt
    10261 ccacctgcta cacctccgac aataacgatt ttcatcttat ttccctccta ctgttcgatc
    10321 aaaccattga ttcatgccac cacgtacatt cactacatca taaccagatt tctttaattc
    10381 tttagctgct tgtttactcc tcatccctga ttgacaaatc acatagacgg tcttttcttt
    10441 gtctccatca tatctgttta tactttgtaa tggaacattt ttagctcctt ttatatgccc
    10501 gccccggtat tctgcaggtg ttctaacatc aagtaacgct ggattttcca aaagcttttc
    10561 ctttaattct gggactgtta tcgattttat tgattgaaat agcaaattca ttttctgcac
    10621 ctcatttaca tttttataaa tacctcatgg ggtatattaa acaggagctt tattaatatg
    10681 tcaaccagaa tgactcttca tttttttcac tactttttat atttgcataa aataccgata
    10741 aggggtatta tctaattata aaaatagagg agaatgtgtt atggagattg ataataaaaa
    10801 tatcctgaac cgtttgaaac gtacagaggg acaaattcgt ggtatccaaa aaatgatcga
    10861 agacgaaaaa gaatgtatgg atgtcatcac tcaattaagc gctgttcgtt ctagtattga
    10921 tcgcgtaatg ggcatgatcg ttgcagataa tctgaaaaat tgctttgaga aacctgatag
    10981 taatccagaa gaacaagcgg ctaaactaga acaagcgatc aagatgatta ttaaaaagta
    11041 aaggaatgat ttcaatgaaa gtcgttttcc atattgatga attagaaaaa tggtcagaaa
    11101 cagggaaaaa cgtaaaaaac ctgataaaag cttctccaga aacgacgatt gtcgtatctg
    11161 taaatggcat cgcgattacc ggttatctag actctgccaa tgcagaattc ttagatttgc
    11221 aaggagtcgt ttttcacgct tgcgccaatg ctatgcgtgc taatcatatt tcagaaagtt
    11281 ctttacctga acaagtaatc gttgtaccag caggtgtcct tgatttagtt gaactgcaat
    11341 cccaaggtta tgcttatatc aagccttagt cagtagaggt tgcgacagaa gtgatcagct
    11401 tcaagaaatt tcggcttatt tttcgaagaa gctacttctg gaaaaccgtg aatcaaaggt
    11461 tgtgaaaacg ctgtcctgca tcaagtaata agaacagcca aacaaaaata gcttctcata
    11521 tttttcgttt ggttgggctt attaccgcag atgcaagctt ttgaacaccg tttaaggaag
    11581 aggttgtgaa atcagcggtt tgacctaagt attagagaaa aaaacgggaa aatagctcct
    11641 catattttgc cgttttttga gctaataccg aaggtcagct gattgaacac cgtttaagga
    11701 agagattgtg aaaaagtcgc ttagtttcga gtattaagaa aaattttgtg aaaatggatt
    11761 tctacatttt tgcataaatt tggcttaata ccgagaaact ggcttttgaa taccgtttaa
    11821 ggaagaggtt gtaaaatcag cggtttgacc tgagtattag agaaacaaac ggaaaaatag
    11881 ctgctcatat tttgccgttt tttgagctaa taccgaaggt cagctgattg aacaccgttt
    11941 accaagaggt tgtgagccta ccatttaact ccgaatcaca agaaataatt tcaaaaacaa
    12001 cttctcctgt ttttggttcg gttggcttat tatcgagaag tagctactgg gagtctattt
    12061 atcaaaaaaa ggaatgcgac ataggtcaca cccctttttt attttctttg aaacatcttt
    12121 cggtactcga cagcatacaa gacaaaagat tgtaaaagac cgtaagtgat gacggcaaaa
    12181 atgactctca cccacagcgt tggtaattct gggaaaagca gcaaaaggat catgccaaca
    12241 tagatgacag cagtcgctac tttgccatac cacttcgctc cacttaattt gatattttta
    12301 gatagcccga ttaatccagc tacaaacata aagccttctt ttatcaagaa tagaccaaac
    12361 aacagccaaa gccacggtcg ataccatgcc atagacaaaa tcagaaaaag ttgtgtcaat
    12421 ttatctgcaa acggatcaag caccttccct aagtctgtta cctgattata tctccgagca
    12481 atgaccccgt ctagataatc agacaaacct gagacaacaa tgaccgctcc tgctatataa
    12541 aatgactgtc tcagcacaaa ataaagataa atcggcagca aaaaaatacg gaatatcgat
    12601 aaaagattcg gaatcgtttg tatttcttta cgccagtctg tgcttaattt cattttatcg
    12661 ccctacctcc tcagcactct tttcttttta ttttagctta cacggggaat aaaaccaatg
    12721 atttcactgt ttttattttt ctttacagac actgatatta tgagctaatt tgagataatc
    12781 acttgctgtt ttcatcgttt actcttcttt cttcctgtcg tttgcgcatt tcttttacta
    12841 gtactttatg agcttttttt gatcctcgct ctaggtcacg ctgccgttta cgtgttttat
    12901 aatcgataaa cagactgtct aaatcgtaac ctgtcgggta cagatcttct gctgaacgca
    12961 ccagacgaac acgctgacga ggcacgtgga ttattttttt gtctaaatat acatcaatcg
    13021 tatcttcacc tatatcttca taaactaacg cttctttttg gtattcattg acaaatatcc
    13081 gatcaccttt tgcaaagagc tgacgttctt ttttattctc cttcctattt gtaactgctg
    13141 tcttaggaag aaattctttt ttctgtgtcc gataggcttt ttccgccaag taacgctctg
    13201 cttgatggat caatttcatc gacatatcca ttttatgagc aatccacaaa gcttggcttt
    13261 ctcctgtttc ttccaacccg caactgatat ttaggacgaa gtgcttcccg atcgaaagcc
    13321 atagcagccg gcacaaaatc ttcatgatct ccggcgaatt tcttgatttc tccataatgg
    13381 gtcgtggcaa tgatcaatgc cccttgctca tacatagatt ccatgattgc gatcgctagt
    13441 gcagcccctt catttggctc tgttccactg ccaatctcat ctaaaagtac caacgtattc
    13501 ctttttatct ttttcaaaat agcagcgatg ttttgcatat gaccagaaaa tgtactcaac
    13561 gcattttcta aattttggtg gtcaccgaca tcgacgaaaa tctcatcaaa gacagcaagc
    13621 tctgtccctt cttttgccgg aacttgcata ccgaacatcg ccatcaaagt caataaaccg
    13681 actgtcttca acacgactgt tttgcctccg gcatttgctc cggtgataat caagcctcga
    13741 tagtctttac cgatttcaac atccaatggt accgcatgct caggtaaaaa tggatgtctg
    13801 ccttgcttga taatgatatg ttccgattta ttgattctag gtgtgcttcc attgatttct
    13861 cggctaaatt ttgcccgagc aaagatgata tctaacaccg tgatcgtttc gatcaataaa
    13921 tcgatcactt cttcgttttc tgcgatagca ccagtcaatg ccgccaggac ttgatattct
    13981 tcactgattt cttcagcttt taacaactga tagtgttcat tcaatttaga aatcacagtt
    14041 ggttcaataa aaaccgtcgt tcttttattt gattcatcga taatcgttcc atctatttta
    14101 tttttatagc tggctttgat aggaatcgta tagtattcgc ctttttgaac aatcattgct
    14161 tcttggatca tttctttgtt tttcggatga cgcaagaatt tcagtaattt tgactggatt
    14221 tctttttcga ttagttgtaa ttgtttgcgt actttacgca aattacgtga cgcgtcgtca
    14281 ctgactttat tattttttat tttctggtca atcaactctt ctacatttat caaatcagga
    14341 agatgtttgc tataagcaaa caacaagggt gtctggtatt gattcttatc aaaaaacttt
    14401 gtgatcatcc gactgcttct aagaaaatcc gcatattcga tcaaatcggt tggctgcaga
    14461 atcaaccctt ttttgacttg ttctgtcagt gcatcgatcc tcggcaaccc cataaatgga
    14521 acatgctgac tgctttctaa gatcaagcgt gcttctcttg tttcttcttg acgatccaag
    14581 acagtttgta ggtttgtcga gaccgtcata tcgctgattc gttttttgct atagtttcca
    14641 attgctcttg cttggatttc ctttttgatc cgatcaaatt gtaattgact aatcatttcg
    14701 ttgtccatat tctctccttt tcttgaagag atacctgtcc caaaataaat aagggcctag
    14761 agataaataa aaggatagaa cacagcttaa aaaagtcatg tcctatcctt attagaatac
    14821 aaagatattg ttttcctgac aggtaccgtt tcataagcac accaaataaa ctttgtttat
    14881 tggctattcg acttactgat tagataccag ctacactcac aaaacatacc ccattcttct
    14941 aggtcttatt tattttccac ttaactatag caagacacat tttggttgtc aaactttagt
    15001 atgttttata gatttacacc attaatgaat agacacctac cgcgataatt gctccgatca
    15061 ttggacctgc gattggtacc catgaatatg cccaatctga agttccttta ttagctattg
    15121 gcaataccgc atgtgctaat cgaggaccaa agtcccgagc agggttgatt gcatatcctg
    15181 ttggccctcc taatgaaaga ccgatggcta agatcaatcc acctacagcg aatacgttcg
    15241 ttccaggtgc aaattcgttt tgtccaaaag ctagcaaccc aagaactaat acaaatgtac
    15301 caattaattc tgtgatcaca tttgctggat aattccgtat agcaggacct gttgcaaacg
    15361 ttcctaaaat cgcgctttca tctttcgttg cattccaatg tggcaaataa gaaagccaaa
    15421 caagaatggc ccctgcaaaa gctcctaaaa cttgcgcaat gatgaaagga acgacaagat
    15481 tccaactaat tgcccctgtc atcgccatag ctagagagac tgcaggattc aaatgagctg
    15541 ggcccatgaa tccagaaata tagacagcca ttgttacagc gagtccccaa ccaaatgcga
    15601 tgacaatcca gccagaagcc tgtgctttac ttttgtttaa attcacagcc gcacacacac
    15661 catctccaag caaaactagg atcagtgtcc caataaactc ccccatgatt tgagtcatat
    15721 cactgttcat ttatttctcc ccctttagtt cccgcagatc tgattctgca atcaatgctt
    15781 ctaaacgttt agtctgttgc gccttctcct cttctgtcca ttcaaaatat ccagcaattg
    15841 catcgatcac aggttgcttg atctcatcaa gctgatctcg ttcaaacaac agatgatttg
    15901 tacgacgaat gagataatcg cctggggcca aaaccatttc ttcttctaaa ccataacgta
    15961 accgagctga ctcagcgaga ctcaaaccag gataaggtgc catttctttt gctaattcaa
    16021 agatacgtcg ggcattagtc ccgtaaaaat cagcgatata agtagcatct tcttcctcta
    16081 aaccggctgc tactccttct tttgctaatt ctgtcactgt ttcttctaat ttagttggat
    16141 cgaagtttcc acctgaaatc tgatattttt tagagtcgat ttctttcgtc tctattccgt
    16201 attcttcttt taataattgg cgtatcaatc gcaaagctcc ttctgccatc ttacggtaat
    16261 cggtgatttt cccaccagat aaagtcagca aaccatctgg ttctctttct aaagaactac
    16321 ctctggaaat cgtagaaggt gctttttcat cacggctgtt ttccaaatgg ttcaacacgt
    16381 cttctacttc agcacgagaa actttgtttt ccttatattc acttactgta tcgacaactt
    16441 tattgaagct cttgtctgaa atcgatccat tatctccacc attgtaatca gaaccagaat
    16501 taccaatcaa cagtggacga agtcctgccc agcttgcttc gatatcattc aatgtgatat
    16561 ttgcttctgg atagcgatga ttgatcacat ccaatagata atctacatct tcttgtgtga
    16621 ctttcggatc cgtaaaatct ccttggtaat ccgtatctgt cgtaccaaag taagtcttgt
    16681 tttctcttgg aatagcaaaa accatccgcc catcttgctt tcctgtatcg aagtatgtgg
    16741 gttgcggtac aggcagtttt ttcgcatcta caactaaatg gatcccttta gttggacgca
    16801 ttttaggaga gactggacgc gtaaaattca agtttcgtac tttatctacc caaggaccac
    16861 tcgtattgat cactaatttt gctttgattt cgatcacttc atctgtcagc aggtcacgag
    16921 ctttgacgcc aacgatttga tcgccatcat ataaaaagcc aaccgctttc attttactta
    16981 ctagataagc cccatcttcg gcagcctttt tgatattatc aatcactaaa cgggcatcat
    17041 tgttgcggaa atctagatag acacccgcgc cttttagccc ttcttttttc aaaaacggtt
    17101 ctctttccaa tacttcttct ggtgtcagcg tataattctc atatttggtt cctgtcacat
    17161 ttgccagttt gtcataaagg tccattgcta ctttgaccga gaacatattg aaggttgttg
    17221 ctccttcgcc ctcatagatt ggcaaaagca ttggatctgg ttttgggatg tgtggggcaa
    17281 tactttgtac gactgcacgt tcaccaactg tgtcagctac tacttccaca tcaaatgtct
    17341 tcagataacg aataccgcca tgaacaagtt tggtcgagcg agaggaagtc ccttctgcaa
    17401 aatcctgcat ttcgatcaat cctgttttga ttcctgatgc tgctgactgg actgccacac
    17461 cggcaccagt gattccgcca ccgatgatca acagatccaa ttcttcttgc tgcatttttt
    17521 gaatgctatc ttgtcttgtc ttgtttgaaa acatatggat ttcctcctta ttcaaatgct
    17581 tgggtagctt ttactgcttt tttccaaccg ttgtaaagtt tttctcggcg ctcttcctcc
    17641 atttgaactt caaatagctt gccagcttca taaaattcgc ggatctcgtc tgtatctttc
    17701 caataaccga cagctaatcc tgctaaaaat gctgccccta gcgccgttgt ttccaagttt
    17761 tctgctcgtt ggatcggtac attcaagata tctgtttgga attgcatcag atattcattg
    17821 tttgctgcac cgccatctac tttcaataca ggaatcttga ttccagtgtc atcttgcatc
    17881 gtatcgatga tatctctcac ttgataagca atcgactgta aagtagcttt aatgatatct
    17941 tcttttgtcg taccacgtgt caagccaaac atagcccctc gtgctgcctg atcccaataa
    18001 ggagcaccta gcccaacgaa tgcaggaaca acataaacct catcttcgct tgtagagcgt
    18061 ttcgctgcgt cttctgaatc gctagctttt tgcaacattt gaagtccatc tctcagccat
    18121 tgaatcgaag aaccagccac aaaaatactt ccttctaaag catagtaaac ctttccattt
    18181 atgccgtaac caattgtcgt caataaatta tttttggata attgcggttt ttcaccggta
    18241 ttcatgacaa taaatgaacc tgtaccataa gtattcttga ccatgcctgg ttcgaatgcc
    18301 atttgtccga ataatgcggc ttgctggtct cctgccatcc ctgaaattgg tgcttcgctt
    18361 ccataaaaat gataaccttg cgtataacca taaacttctg agttagaagt gacttttggt
    18421 aacatcactc gaggaatatt tagtaaatct aaaatctcct gatcccaatc tagctgatgg
    18481 atattgaaca acatcgtccg actggcattc gagtaatcag taacatgtgc ttgtccatcg
    18541 gtcagtttcc atactaacca agaatcgatc gttccaaaca tcaattcgcc tttttcagct
    18601 cgttcttgcg cgccttctac atgatcaaga atccagcgta tcttcgttgc tgagaaatag
    18661 gcatcgatca ctaaccctgt tttttcgtgg aaaaattctt gatagccttc attttttaag
    18721 ttatctgcaa ttccagctga ctgtctggat tgccaaacaa ctgcatgata gattggacgt
    18781 cctgtatctt tttcccatat tactgttgtt tcacgctggt tcgttatgcc aatcccagca
    18841 atctgatttg gtttgatccc tgattcgatg aacgctccgg caataactga ctgtacagaa
    18901 ttccagattt catttgcatc atgttccacc caactttctt gcgggaaata ttgcgtgaac
    18961 tctttttgag aactgccgat gtgtcttcct ttcttgtcaa agataattgc tcgtgagcta
    19021 gttgtacctt ggtcaatcgc catgatatac gttgattctg tcattgtgat tccctccatt
    19081 atatgcaaac gctttcttta actactctta tcatactact gttttaaaaa aagaaactgt
    19141 caaaatttta ttcttttttt ctttttttga cagtttttta ttatgaagct attttttaat
    19201 caattctttt cttttttcag cgtctctatt cttcttttca atcgaataat gtcgtaaggt
    19261 gacgcaaatt ctgacagata atattcacac tgttttttgt ttctctggca aaatgtgatc
    19321 accaaatcat attctttacc ttcttcataa cttccaatct caataccgcc gattcccctc
    19381 agttctctga tcagatattg ttgaaaagca atacgataaa tcggcagact ttctaaatcg
    19441 attccaatca ctactggttt tgcaatataa aaatcgatca tcaaaagaac attggcatac
    19501 tggatcatca ggtaactaag ctcactatct tcagctcttt tcctcggcaa ttgctgcacc
    19561 gctgtttcct gtaatttcgc cagtaactgt gttaaggaat gcccgagcat tttctgctgc
    19621 tgttccaaaa gccgatcacg ctcatagact tcgatctttc caacaaagaa aaaccattca
    19681 ttgttgatct gggaaatttg gtagcctact gccttttctt ctttgatttt caaacgacga
    19741 ggacgataat gccataacat cgtttcccga atgtaagtat ctaaaacagc ggttggtaac
    19801 tttttgctcc gtgtcaaatc atactgataa aatatttctt cgtctactat cgaaaaagaa
    19861 acaaaaaagc tgtaaaacat cattgtttcg tatacattca gttctgctgc tgttcgacta
    19921 agatgcatca cgatgattgg atcgattgct tgataaagcc ggtccgactg atagagtaat
    19981 ttcttttctt tcaaagttgc gtacgtactt ttttcattca atagtctttt tttcgtaatc
    20041 ccgagccagc aagcaatctg tgcttctgct gatgccgtaa acgttgtttc taatacacgg
    20101 tccaatccta gaatgaacgg tcttttttct ggtgtatttt gcaaaaaaag cggtcgctga
    20161 tcttccggga tatattggaa tagttcataa taaaaatatc gtatctgtag ctcttctccg
    20221 tataattgac cgtttttgat ttgtaatcca aattcctcta agagctggtt caattctttg
    20281 atctttcgaa aaacagaaga ctcactgata ttaaacgctg tcgctaatcg aacgatggat
    20341 acttgctgat gttctaataa atagacgagc atcttaaact tcaagctttc ctgcaataaa
    20401 aacaatagaa ttttttccaa acttacatct tcgtccaaca caagcagcgc ctgatactca
    20461 tttcgctgta cttctacttt tttttccatc attcggccaa tcaattcaat atcttccaaa
    20521 tattgatcaa acgaggcttt tgacagttgg acatgctctc tcaaaccatt gatagaggct
    20581 gttccccctt gcagaacaag gtttcgcaaa atcaggatct gtaactgctc ttttctttct
    20641 aataatgctt caatcttcat aggcagtatt cgccaccttt gaccacacca tatctggcac
    20701 acggtattct ggctggaaaa atagctcatg ttcttctaac tgttcaaacg tccatccttc
    20761 ttctactgca attgtcagtt ggtcaagaag gtggaacatc tcttttttgc tttggagctg
    20821 tgctccaaga atcttttttt cagaatcaaa tagaaatttg agtttaactt tgctttgatt
    20881 tattgctgta agcttgtagt ctacgtatcc tgtttcaatt ttttggggat aaaaaatgct
    20941 ctcttcttct gtcaaaccta cgcttcctaa gaaatagcca aaccactgat tgccgactgg
    21001 acgataggtt ccctgatcct ttgtctgtga gccactaatt gtcttgctga catttcgtgc
    21061 tgtacggaca gcgttattta ctagagaaac atacattttt tcatttgttg gacgaaaagt
    21121 tacttggatc gcatcgccaa tcgcataaac gtctttttga gacgtttgca agtagtcatc
    21181 tacccagatc gttccatcat cattcaatgt taattgttct tcccacatct gattgtcggg
    21241 acgagaatga ttagccagca aaacaagatc atagttctcc tttctttttt ccgtctctac
    21301 aatagcggtt tcattttcgg tcaaagacac aacttgttct tctaaaaaaa gtgaaagccc
    21361 ttgatttttc atttccttta ctaacggttc tgtcatttca ggatctagat aacgaaaaag
    21421 aattgacttt cggctttcgt aaagatggat ttgttttttt cttgatgcca acccttcagc
    21481 tatttcgatt cctgcttgtc ctgcaccaat aattgcaatt ttctttgcat tcatgatctt
    21541 ttgctgaaga gccgttacgt tttgtatctt tttaactggg tgaataagcg ttgattctgc
    21601 agaaatattt cgaaactttt gatttgaacc agtcgctaga atcaaacgat caaaatccaa
    21661 tttttttcct cctgctaaaa cgactttttt ttctttcaat cctattactg tcttttctgt
    21721 gtaaacatgg attcgatagc ggtcagtcag ttcttctttc gtgatccaag aaagttgttt
    21781 ttcactggta acctttcctt ttaatatcaa attgaacccg ctgggaatcc atcctaactt
    21841 cgattgcttt tcaatcaaat atatttcact tgttggcatc aattggcgaa gataaatagc
    21901 cgcatgaatc cctgcaaacg acccgccgac aattacaatg ttcatctgca ttcctctttc
    21961 ttataaggtg ttctactgct aacttctcaa tcagaaaaca cagtattcat aactcgcttt
    22021 caaccttatg atacatagcg atgcagcaga atcaaccctc tccatcatac cgtgttctag
    22081 gtctgcttct caataatgta ctagtggacc taattgaaga gtatcatttc tgaagagatg
    22141 tttcaaaaaa tgtactctta taaaagaaaa aaactcgcct tttacgtacc tctgtccaaa
    22201 taggaaacag aaaagaacga aaagacgagt tttagcgtgt gtaatgtaat agttagaata
    22261 gacacatcat ttatttttaa ttctttaatg cttcaacaac tgcttcgcct aattgatgag
    22321 cagattgagg attttgccct gtaagaagcc gcccatcaat ttgaaccact tctgaaaaag
    22381 ctgctccaga ctgatagttt gctccttttt ctttcaaagc atcttctgct aagaatggta
    22441 cttcattcgt tgtaccattt gcttcctctt cttcattact gaacccagtc actgtacgtc
    22501 cagctaaaat agattttcca gactcatctg taactggcaa caatcctaca acaccgtgac
    22561 aaacagctga gaccagccct tcatttcgat agatttgtga agcgactttc ccaagatcta
    22621 ttgcttctgg aaaatcccac attgttccgt ggccaccagc ataataaacc gctgcataat
    22681 catttgcatc cacatcatca ggacgtaagg tatttcccaa ggcccgattt ctgaaatctt
    22741 catcttcata ataggcccaa tcgatttcat ccatattcaa aacactttgc ggttctaaag
    22801 gtacatatcc gcctttagga ctgacaaaat ctgcatcgat cccatttttt actaatacat
    22861 cataaaaatg agtcagttca cttaaccaca aacctgtagg acgctcgatc ttttcgtact
    22921 tttctacatt tgttaatacg atcaatactt tcattttccc atcctctttc tataaaaatt
    22981 gcgttattga taacgtgctt tcaagaaatt atataatggg cttggcaaat aaagctcttt
    23041 atatgcttct tcaaaaggtt tcgttacaaa ttcatcctca cggttttcca ataatttctc
    23101 tgcccagtca ggatcgacga tcatttgctg tccaattgct gcaagttctg catatttcaa
    23161 tacctgctct acatcttcgc gattgcggat cccaccgaca ccaactaaag ggatctttcc
    23221 ttgaatcgtg ttatggacca cttcaagaat cgatttatcg ttgtatttat cagaacgagc
    23281 tattcgatca tacatattta atgaaacatg cagataatct agttttgact cacgtaatcg
    23341 ttcaagaagc cagatcgtgt cttcaaaacg gatacctggt gtttcatatt cttctggtga
    23401 gaaacgatac cctacgatga atggtttttt agcatattgt tcaaccgctg agaaaaccgt
    23461 tgttaataat tcttcaataa aacgataacg attttccaag ctaccgcccc attgatcctc
    23521 tcgtctattc gaatgcggag agaaaaattg ttggatcaaa tacgtatttg ctccatgcaa
    23581 ctcgattcca tcaaatcctg attcaatcgc tctacgtgtg gctttgccaa atgcttggat
    23641 tgtttcaacg atttcttctt cactcattgc tcgtggtgtt tccgcatcag gacgttttgc
    23701 tgcaactgca cttgcagata caggctgttc tccagataaa gttgctcgac ttgtcattcg
    23761 tccaccgtgg aaaatctgaa taatcgcttt tgcgccttct ccttggattg ctttcgctag
    23821 ctcacttaat cgaggaatca tttcatcatg agcgatgctg agttcacctg gccagccttt
    23881 tccgatatct tggacatttg cagcaccagt aataacagca ccaagacctt tagaacgttg
    23941 tttataataa gtgatctcat cttcggtgat cactccattg aaaaagctga gttgtgtcgt
    24001 cataggcgac agcatcaatc ggttcttcaa ttgaactcct gaaggtaaag taattgattg
    24061 atcaaattgt gacattgtca ttcctcccat aattcgctct gattaaccta tcgagaatca
    24121 tctatcatta aaccactcga ttagttgtac atgcaactaa tttgcttaaa aaattttatt
    24181 ttttttgtaa cttatctgtt gcatcattca ttgtctgggc taattcttta cttgcttcat
    24241 ttcccaaaac tgctttgtat gactgatgaa gttcttccca gctaccatcg acttccttag
    24301 caaattggcg tccttgttct gtaagataaa ctaatgacaa gcgaccttcg ctaactgttt
    24361 tgacgtatcc tttatattct aatttttcaa caaaacgagc aatcgttgat ggggcggaat
    24421 agagcatttg tgcaatatct ttttgtggta ttccatcttt ttcttttaat atcaataaaa
    24481 taaaaccata agttggtgcc agacctgtcc ttctaaacgc ttcatcagct aatttattca
    24541 acatgcgatc tagctttttc acgctaaaga aaagacattc atctaacgct ttttcaattg
    24601 gcttttccat ttcatcccct ccattggcgt acatatcata gtatgatttt tattttttgt
    24661 caaaaaacac ggaataatgt ccgcctcctc tgtctagatt tgaaaaaaag aagtagccat
    24721 cttcaaagaa tttcggcttg ttttcgacaa aactccttct ggaacaccgt gaatcagagg
    24781 ttgtgaaaaa gtcgtttagt tttgagtatg aagaaaaatt ttgtgaaaat ggctttccac
    24841 atttttgcat aaatttggct taataccgaa aaactggctt ttgaacaccg tttatatcag
    24901 aggttgtgaa aaagccgtcc tgcatcaagt aataagaaca gccaaacaaa aatagttcct
    24961 catattttgt cgttttttga gctaatgccg atggtcagct gattgtacac cgtttattga
    25021 gaggtcgtga gcctgccgtt gaactccgag tcacaaggag caatttcaaa aaacagcttc
    25081 tcatgtttta tgactatggt gacttgtgat cgaggagttg gcaggagaat actgtttatt
    25141 cgtaaagaag gggctgtgac aagacttttg tcacagtccc ttatttcctt ttattatagg
    25201 atttcgccat ttgattggat gacttgtctg taccaatcaa atgatttttt ctttaaccgt
    25261 ttctttgtgc cattcccttc gtcatcttga tcaacataga tatatccata acgttttgac
    25321 atttgtgaag tagaagcgct gacgatatca atgcagcccc acgacgtata accaaataaa
    25381 tctactccat ctttgatagc ttccttcatc tgctcaatat gctgcttcaa atagtcaatg
    25441 cggtaatcgt cttgaacggt tccatcttct tctactttgt ctatagctcc gagtccgttt
    25501 tcagctatga acagtggttt ttgataccta tcatataatt gattcaaagc aattctcaaa
    25561 cccttaggat caatctgcca gccccattca cttgatggaa gatacggatt tttaattcct
    25621 ccagttatta agtttccttg gaccccttcc caattttctg gatgagcact gactgcacta
    25681 gacatgtagt agctaaaaga aacaaaatca acagggtagg ctgctaagat ttcttcatca
    25741 cctacttcta tttttaagtt gacacctttt tcttcaaaca ttcgttgcgt atacgctgga
    25801 taatatcctc ttgcttgaac atcactaaag aacaaagaag ttctttgctg ctcaattgtt
    25861 ttttgaatat catccggatc acaagaatac ggaacaagaa gctgatagct gatcatacaa
    25921 ccgacttgtg aacctttgat aatttcatga caagcttttg tagctaaagc acttgctata
    25981 aactgatggt gtgcaccttg gtatttcgct tgttccaaat ggggatggtt ttcttcaatt
    26041 actcctacgc taacaaaagg gtgatgtttt acacagttga tctcattgaa agtcatccaa
    26101 tattttactt tatttttata gcgtttgaat actgtttcag cgaaacgaac gtaaaactga
    26161 ataagctttc gattaggcca tccaccatat tctgtaacca aatataacgg catttcataa
    26221 tgggaaagag aaacgactgg ctcaatccca tattttagac attcgtcaaa cacttgatca
    26281 taaaaaaata atcccgcttc attgggtgtt tcttcatcac catgaggaaa aattcttgtc
    26341 catgcgatag acatccgata gcatttaaaa cccatttcag caaataaacg gatgtcttct
    26401 ttaaagtgat gatagaaatc atttccgtgt cttttaggat aataatactt gctgttggga
    26461 tcctgcgccg cttttacttg ctgatgcgtc atcatatgcc attgatctgt ccatttttct
    26521 ttaggtaaat cgctgtcgaa tgtatacaca tcagacacag ataatccttt ttcatctaca
    26581 tcccatgcac cttcacattg attggccgct gtcgctccgc cccataaaaa tccttctgga
    26641 aattttttca tatcgatccc cctaaacttg ctagttttct tgtttgatta tttttcttat
    26701 gactagtaat gatatttttg aatctactac tatttgtaac aataaccatt gtggtcggat
    26761 catatccctc tttgattaat tcttgcaaat ctacttccat caataaatcg cctttacgta
    26821 ctttttttcc atcagatact gcactttgaa agtatttgcc atttaaattc actgtatcaa
    26881 taccgatatg gatcagtatc tctgctcctt cttcactgac taccccaatt gcatgtttcg
    26941 ttggaaaaac tgttgaaact tccccgttta cagaactgta gatttttccg tccgttggaa
    27001 tgatcgcaaa cccttctcct aaagatccac tagcaaatgt tggatcgttt acttcagata
    27061 aatcaattat ttcacctgct gcaggagtac ttaacactat atcctttgag gattcttctt
    27121 cgatttcatc cttgtagccg aaaagaaaag ttagcataca ggaactgatc atcgctaaga
    27181 aataactagc aactagccaa acaaatcctt caccaatata aatcgggaaa gacaaaatac
    27241 ttcttgtagc aactgccaaa gcaccggctc ctgcggcacc agctactcca ccaaatatag
    27301 ctccacatat acaagcaatg taaaatggtc gtttatattt aagagtcaca ccataaacag
    27361 caggttcagt gattccaaat aatgctgtga taaatgcaga taaagataaa ctttttactt
    27421 tcttattttt cgttttcaaa aataccccaa gtactgctcc tgcttgcgca gctacggcag
    27481 tcatacatgc tggacctagc gtatcacgac cgtagaaaga aagattgttg gtcattactg
    27541 gtacaagtcc ccaatgtaac ccaaaaatca ctaacacttg ccaaaatccg ccgataacag
    27601 caccagataa aacagggcta aagttataaa cagctaaata tccagctgca atcagctgac
    27661 ttgcataatc tgcaattgga cctacaacta ataaaataat tgggaccatc acgatgatac
    27721 aaatgaatgg tgtcaataaa tttcgaatac tttcgtgcaa gcttttgcga atcttaggct
    27781 caatataaga aagaacccat acagctaaaa ttgctggaat aaccgtactt gtataccttg
    27841 ctagaatcac gggcatccct agaaatcgca aggttatgct atcactatat gcactgacaa
    27901 tcgtaggata aacgagagct gctgcaataa ccatagcgat gaaacgatct gtattgaact
    27961 tttttgcagc agtatatgcc aaaaatatag gcaagaaata gaaaaatgca tcagctgctg
    28021 cattcaaaat gatataagtt cctgattcag tagttaataa attcaaactc gtacataagg
    28081 cgagtactcc tttgatcaaa ccacttcctg ccaagacgcc taaagtcggg gcaaaaacag
    28141 cggcgatcat gtctataaaa gagtttaaaa tgcctttttt ctcagttcct ctctttccac
    28201 tagatgcatc atcttctagt ttcatttgtt tggataatac gtcatacact tcatttactg
    28261 catttcctac tacgacttga aacattcctc cagcttcgac tacagtgatc acaccttcta
    28321 gttgctctac cttctcctta tctgccttct tattatcttt tagggtaaag cgtaaccttg
    28381 ttgcacaatg gtaaacattg ctgacatttt cttcgcctcc gacaaatcgg acaatatctt
    28441 tcgctaattg tgaatagtcc atttttactt cccccttgtt aattaatgcc gtagcaatcc
    28501 ttcttacaag ataagtatag ttcttagaaa acggtttctc cattcaatta gtaccccttc
    28561 taatagcgaa cgaaactgta caatagtgtg tatggtttac ttagccgagc aaatcactca
    28621 ctgcttgaaa gaaaacaagt atatcgtttc tcttatagtc aaaggagaca aaaaaaacac
    28681 gcttgatctt cctttgctga tgtataagtg gtatctcaag ctgatactct gtgatttttg
    28741 tttctacttg gcttttgata agacagcaca acaaagtctc ggcatttaac ggaagcataa
    28801 ctaggtcaga actaggagag attagttgct gaatggaatc tatcttttta tggattttta
    28861 tttgattttc ttctttgtag taatgatcaa gcagttttgt tttctttttt tcttcaacta
    28921 tggtcagctt ttcacgcaaa atctgataaa tctcccaaga ttcaaactca tctagaacac
    28981 taggtagata aatcaaatca tcccactcaa aaataagctc ttgctcagta gtcaaaattg
    29041 catcatattc cgttattttg tttgattgat ttttgaaaag atacactggt tctatccggc
    29101 attctttgat ccacatgttc atactttgtt gaatctgttt ttttagtgta ttcaaaatac
    29161 taattggctg gttactaaca atcagtatct ccccttgttt tcgaaaagga ttcaacgctt
    29221 cggcaagata caaaacaaaa taagcgcttt cagctaaatt gggacgtaat tgaaaatgta
    29281 ttgggaagaa acgccgaatt aaataaattt ctaaaggata acgggagatg atcttttgta
    29341 caaaatgatt catggtatta tgtccggcat ccatcctcgt tttcatttgt ttgatatggg
    29401 ttagcaaaaa ttctgtttca tggaacaata acgaaacagg aagatctaaa aaacgaataa
    29461 tcgtttgctc aaatgctctt agattcttct ctatttcttt gtttttttca tcattaatca
    29521 tcaaataatt taactctaat agtcgatttt caattgcttg tttttcttga ttggaaaaag
    29581 aatagggtag ttctgatgat aacttttttg tgagggtctc taccatcgga ataaataatg
    29641 tatacctgtt tgttttttct aaaagttctt ctcttcgaag aatggtcaaa acgagatacc
    29701 gagaaaatcg tatgaagtcc tctcctgaaa caatataatt atatgatata agaacctctt
    29761 ttaatgtctt ttggacagtc ggcatgatat tggaaaaaat tgtactgatt tgttgaggaa
    29821 accttgcgtg ttggatcacc gtttctgttc caacaagaga taagaaaatt ctttttgaat
    29881 tttcttcagc aatgattttt agtccttttg tcgacgaaac ttccagttct aatttaggat
    29941 tgcgctcgat ccaacgcaaa atcgttttta tttgtaatga tacggctgtt tttgaaagaa
    30001 agaaaatgtc tgctatcttt tgcatactga catacccttt ttgaaacaat aagtacgtca
    30061 caatagttga agctcggaaa tccatgctgg aatagatttt atgtttcgtc acctcttgta
    30121 tgatttgctg tttagtttca gattcaattg attctaaaaa ataacctgaa cgtttatttg
    30181 actggataat gattttcttc tcgtagatag caagcatatt tttgatttca gtttggatcg
    30241 ttttcttgtt ggtacctaaa gcttcagcta attcttcgct tgttatccaa tgattcttat
    30301 ttcttaatac tacaagaatt tggagttgtc gtttatttaa gtccatttgc ttacacctcc
    30361 tctttgttat aaacatacag gaaaaacctc tcaaatgaca atagtcactt gcagaggttt
    30421 aaaaatcatt tgaagaaaga tctatattca aggtttttac cattagactg gataatttgt
    30481 ttataatatt caaaactatc ttttttcaat ctcctaaagc ttccgctccc atcattttgt
    30541 ctatccacat aaataaagcc atatcgcttc ctcatttccc ctgttcctgc cgatacgata
    30601 tcgattggtc cccaccataa gtaaccaatg atttggcaac catcttttat tgcctcagca
    30661 atttcctgaa gatgtatttt tagatactca caacgttttg gatcgtggat tcgattcaat
    30721 tcatctggtg cttcatctag tccaatgcca ttttcaacta tgaataatgg taattcataa
    30781 cggtctgtca attcattcat gacataacga aaccctagag gatcaattgg ccaactccaa
    30841 ggttcgggag atttttcctt caaaaaggga ttatcgaaac catttgctcc gccagtatct
    30901 acgcgcattt ctgcttcttt tttatagaca gcgctacgat aataactaaa tgcaatataa
    30961 tctgccgtgt tagcttgcaa gcactgttcg tctccatcta acattactgg tgcacagtct
    31021 tcttccttcc atgtcctgta aatataagct ggataatgcc ctcggcacat gacatcggag
    31081 aaaaaccatg aattgcgttt aaattgcagt gaaccaaata cattctctgg atcacagtca
    31141 tatgcataag tcgctaatgc agaaaagcta cacataatac ccatcttagc atttggatcg
    31201 attttcttta ataattgagt agcacgggcg ttcgctagaa acatatgatg acaggcttga
    31261 taaatcactt tttttgttag tgtagcaatg ggttcaagtt tatctctagc agggaatgta
    31321 accaatccag cagctgcata aggcatacga aaagcattat tgatctcatt aaaggtcatc
    31381 caatatttca ctttcccttg gtagcgttca aagacggtct gcgcataaaa ttcaaaaaag
    31441 tcgattaatt ttcgattttg ccacccccca tactctccta ccaatgctaa gggggtttca
    31501 taatgactaa gagtaattac tggctcgata tcatatcgat ttaatgtatt gattagtctg
    31561 tcataaaata cgagaccagc ctcatttggc ttctgttcgt ctcctcttgg aaatattcgt
    31621 gcccatgaga tgcttgttcg aaaagctttt aaacctaact ccttcagtaa acgaatatcc
    31681 tcttcaaatc gatgataaaa atcaatcgct tcatgagaaa gataatggag tgattcgtct
    31741 aaagcaatct cccaaatctt tttttcttca ttccactgaa tactaggatg ctggttcatg
    31801 atcccgataa gcgtatctgt cacattaggt aatttgccgt cttccaacca tgcaccttca
    31861 cattgattag cagctactgc tccgccccat aaaaaatttt ctggaaatat ttcctgatcc
    31921 ataactatct ctcctcgcta tcaacaattt cttacttgaa gtatagctcg attcatcaaa
    31981 acaagatatt ctaactattt cggcagaaga gaagaaaaaa attgaatgct actcttcatt
    32041 tttaatattt atatataaca aatacataag acgatccccg aaagaaaaca ctcgttaacc
    32101 atctaagcaa acgatttatt ttacttccaa cacaaatgct tcataaggtc gtaaatcaac
    32161 tttgccgtct ggtaactgtt tcagaggata atttgacaca ataaccctta aagcttcacg
    32221 tggaatagtg aacgtctgct tttcactgga catattacaa ataacgagcc attgctggtc
    32281 ttcatatatg cgagaatagg caaagacatg ctcaggcgtc ttttccacta attcatagtc
    32341 tccccagacg atgatgtcat gttttctacg caaatcgatc aatttcttgt acatataaaa
    32401 aacagaatct tgatctgcta acgcttcttc tgcattgatt tctttataat ttggattgac
    32461 tcgaagccat ggaattccag tagtaaaccc agcatgttca cgggcgttcc attgcatagg
    32521 cgtcctagca ttgtctcttc ctttcgcctt gattgattcc aagatttcct cttttgtaaa
    32581 tccagaagaa atcctttcgt tatacatatt gattgtctca atatcttttg cttccgcgat
    32641 atcatcgatt gggcaattcg tcatgcctaa ctcttctcct tgatagatat aaggggtgcc
    32701 tttcatcata tggagcaaga tagcaaacat cttggcactt tcttttcgat acacatcgtc
    32761 atttccccaa cgagaaacaa ttcgcggaag atcgtgatta ttccaaaata aactattcca
    32821 tccttcatca cctaaagatg tttgccattt ggataatact tttttcagtt cagagatact
    32881 caagggtttc aaatcccatt tgtctttgcc ttcttgctga tctaatccta tgtgttcgaa
    32941 ttggaagacc atggataatt catttctttt aggattggaa taaagtttag cgatttcggt
    33001 agttgctccc catgtttcgc caacagtcat cagatttttg tcaccaaaag ttgcttgatt
    33061 catttcctga agatactcat gcagtttagg tccattactt gtgatttctt tatccggttc
    33121 tttgccaatc atatcgatca cgtccatacg aaagccccca atacctttat cgatccagaa
    33181 attcatcatt tgataaatct cttggcgaac ctgtttattt ttccaattca aatcaggttg
    33241 acgcttgcta tacaagtgca gaaaatattg ccccgttttt tcatccaact gccaagcaga
    33301 accactgaat attgagcgca atctattagg ctcttttcca ttgaccggat cacgccaaat
    33361 ataatagtcc cgataaggat tttctttatt tttacgggcc tcaatgaacc acggatgttc
    33421 atcagaagta tgattcacca ccagatccat gatgatacgg atatttcttt tctttgcttc
    33481 ttcaatcagt tcttccattt cttccatcgt accgaattct gccatgattg cttgataatt
    33541 actgatatca tacccattgt catcattcgg agactcgtat actggagaaa gccaaattgc
    33601 atcaatacct aaatacgcca gataatccaa cctggaaata atcccccgca aatctccaat
    33661 accatcttga tttgaatctt gaaaacttct tggatagatt tgataaacaa ctgaatggtg
    33721 ccaccatttt tgttccatga ttttcctcct ataaatggat gtttctattt tttgcttaat
    33781 catttatttt agtctctctc actaaaaatt gtaacgcttt caaatagcta ttgcaccttg
    33841 ttatcggtaa cagaataaaa caaaaaaaca gctgaggaaa ttccctcaac tgttttttga
    33901 aaggattgat ttatgcaggg aagaatgctg atttcacaac ttctttataa acggtgttca
    33961 ctcagctgtc ccttggtatt agctcaaaaa acggcaaaat ataagaaact attttttcgt
    34021 ttttttctct aatactcagg ccagaacgct gatttcacaa cctctttatt tcacattcaa
    34081 tatccacatg aatcccacaa atacaaagaa cagaccatac atgattggag atacttcttt
    34141 tcctctttta gctgctaaca tggtaattgg atagaagata aaacctaatg caatcccatc
    34201 tgaaatacta taagtcaaag gcatgccgat caagatcaag aatgaaggga tcgcaatctc
    34261 taagtttccc cattcgattt gtcgcaaaga ttgtgccatc aatactccta ccataatcaa
    34321 tgctggtgca gttacttgtg aagtaacaac tgatagtaat ggagaaaaga acaagcctaa
    34381 caagaagaaa atccctgtag taatagctgt gatacctgaa cgtcctccaa cggcgatacc
    34441 agctgatgat tctacaaatg caccaacagg agaagtacca aataaggaac ccgcaagcat
    34501 agctgttgaa tcagaagcta aagctttccc tacacgaggc atcttgttgt ctttcatgaa
    34561 acctgcttgg tttgctaatc caactaaagt tcctgctgta tcaaagaaag tcacaagcaa
    34621 gaatgtcagc actacgaccc acatttgaag agaattgatg tcccctacat gttttaatgc
    34681 aactaaaaat gttggtttca aacttggtgc tgcggcaaca atttcagaag gcattggaat
    34741 caaacctgtg accagaccta aaatcgttgt agctgccatc ccgatgaaga tgccacctgg
    34801 tacacgccga acaagcaaga tagcagttac gactaatcca aaaatcgtca accaagtaga
    34861 accaacgttg agtgatccta atcctactaa tgtagattca ttcgaaacga tgatcccacc
    34921 ttcgctcaga ccaaggaaag cgataaatag accgataccg ccagaaatcg catatttcaa
    34981 atctgctggg atcgcatcaa tgatcatttc ccgcagcttg aagattgtga tcaaaataaa
    35041 aatcaaagaa gcaacgaata cgccggctaa tgctgtttcc catggaatcc ccattcctaa
    35101 acaaacagaa taagcaaaaa aagcattgat cccaagagca ggtgccgttc caattggata
    35161 acgggctaat acccccatta aaacacagcc gatcgcactg gctaatgcag tcgcagtaaa
    35221 cactgctcct tcatccattc cagaagcacc taatacagtt ggatttacaa ataagatata
    35281 agccattgag ataaatgttg taaatcctgc cagtacctca cgttttaccg tggtgttcaa
    35341 tttttctatt tcgaagtagg aaagtatttt ttccttcatc ttccatcccc ctaaatccga
    35401 acattataaa taaagtccgt taaaatttcg atttattaat aaaacaacgt gttttatcat
    35461 atactaaaac aaaacataag taaacaaaaa attcggattt taagcaaaat ccgaacgttc
    35521 catctgatta aatcccttta tctcaaagtt catgaacatt cactttggat tacaagaatt
    35581 tctttattgt gttaataaag tttcttcatt ctagtctcaa aaatcaatag tgtgatttga
    35641 ttttaccatt tcgtttctgt tcttctttga tgaattcttt tgtatcgaca ggattcagat
    35701 tatttagtcc gccaaaacct gtatcgacca tttttcccca gccttttgtc ttcttttttc
    35761 ctgatttgag attctttgct cgaagcttct cactatgttt tgctcgccga tacttcaaat
    35821 aaccttctaa tcttcccatt agatccactg tttttcctcc tttttattca atcagacgac
    35881 tcagcttttc ctataacaaa ataattgcct tcagggtcag aaaaattgaa agtcaagatg
    35941 ccattgttat ctgtgatttc tcctggttct tccatgttct cgtagatagt ttcaaattca
    36001 tccgtaaaaa atactaaaga aggcggtggt cctaatacct ctggtgaaaa cttctgcaca
    36061 aatacttttg ggaatacgcc taattctaat tcttttgaga tgctgagtac aatactctta
    36121 aattcttctg gcaattcgat tgtttcagaa atttctgcac caattttttc tacaaagaat
    36181 cggcaaatca tctctacgtc attgacataa agcatcacac gtgttttttg tatcatcatt
    36241 tgacccttct ttctatttga ttttctttcc tgtctataaa ctgattccat tatatcacga
    36301 aagcgcaaac accttgtgtt tgatactatt caagaaaaat aaagcaatag tttctaggat
    36361 tgctttcctc cacaaacttt ttttacaaaa aaaaaacggc aatgaatgcc gctcttctta
    36421 tttcgattct tttataattc tgcttctgat tcatctttgg ttagtgtgtg tctaacacta
    36481 gttacgccaa atgtttgatc gattttttcc ttcaacgctt cgattgcctg tgcgccacgt
    36541 gccgcttgtt cagcattgat ggattcaatg accagcaccg ctgcttgtgt ttcttccgtc
    36601 agcatcgttc tttgggcttc acgccagttg agacagcgac agatcgctcc ttgttcatca
    36661 tagtagatga tttcttccgg aagtgccgga gcatcggaat ctgcacctaa aggcaggaat
    36721 gattcgccac cttgggcttt tcctaaatgc agatttcctg cgatcttttc gatatcttct
    36781 ccgccgcaag gtacgccaaa agacaaggaa atactattat agatatctac aagcggattg
    36841 attgggaaaa attcccgttc ttgatttgca cgtttcagta aagcttcaat agaagaacgt
    36901 gcaccttttt tagtcttgaa tgtggtaaat gcctgacgcc actgagcaat gacttcgttt
    36961 tggctgaatg tttcttctgt aaggtaattt cttgcttctt ttgctgcctc attcaataat
    37021 tgatgatacg tttcttcact ttcttttgtt acgtggttat cgataccatt tacggataag
    37081 atttcgatgg ttgcttcagg aaatacttcc cagaaattgg tatccactat tacttttttc
    37141 atctgttcac acctcttgat tagaataatt gcttgatgaa tagatagtct gtttggggat
    37201 catctcccat ataaaaaaca tgttcgctgt atttgataaa tcctttttta cgataaaaag
    37261 cgagcgcaac atcgttgtgt tcccaaacac cgagccaaat ggctgttttt tgcttttctt
    37321 ttgctttttc aatagctgta tctagtaaaa atgtaccgat accttgatgt ttaaattttt
    37381 ttcgtacata gattcgctcg atttctaaaa aatgatcagc catttcctca gattgactcg
    37441 ttcctgtatt tagtttcagg taacccgcag gctcttgatc gatactcact aggaaaaaat
    37501 cggtttcttt atcttttagc tcttctgtaa gtttttctag tgcataagct tgtgtcaagt
    37561 aatcagctaa atgctccggt gaattatctt ttccaaatgt atctgtaaat gtttcgatac
    37621 taatttgttg tagtaagtct acatctgaag gcgtcatttt tcgaatttcg tatttattca
    37681 cggcttcttc ctttcaatag atccttttat tgcctttttt gacaaaattc caatcttcgc
    37741 taacattctt gcatacttta tttaaaagat attccaattg ttttgcttct tcgtcagaaa
    37801 gaccatttaa tgcgactgca ttggagtagt tgttttctcg aatgatgaaa ggatagattt
    37861 ctgctccttt tttagtcgga tagagtttct tgattttttt attttcttta tcttccaaac
    37921 gttcgatcat cccattggat tctaatttct tgattgctcg ggcagtcgtt gtacgatcta
    37981 ctttgatcat ttctgctagt ttttcttgga tgattccagg attttcgcaa atacgtacta
    38041 aataaagata ctgtcctctt gttaaatcga cttctttgaa ttcgatattg ctaatagaat
    38101 ctagcgctcg ggcaatcatt ccgatgtctc gaaggatttc agccatttca tcccaccttt
    38161 attttgtttg taagactagt tcacctcttt ttgttgcaaa tgcaactatt ttcaataaaa
    38221 aaatcaagtt cttttttaat aactagtaaa gtatattctt ttcttctttt acgaaaaagc
    38281 tcaatcacaa tagatctggt ttttgttttc taaaataagt aactgtttct tcgttgttcg
    38341 cttttctgat agctttggca actcttctat actaaaaaat cccatgttgg aagtttcatt
    38401 attctcaata aacttggcct cttcaccgtg gatcgcacaa gcaaaaacaa gtttataata
    38461 ctgaaaaagc tgtggaatat ctttttgttt attcgtatca aaaactgctc gcaactgagt
    38521 agtttctact gttaatcctg tttcttcata gacttcttta cgcacatttt cttcaggaga
    38581 caatcctatt tcagcaaatc caccaggaag tgaccattct ttcgtccgtt tatcttcgat
    38641 tagtaggacc ttgccatctt ttttgatata ggcacgaaca tctacttttg gtgttggatg
    38701 tccttctcca atcgttgtga gcgcttttat ttcttcgaaa gtttcttttc ctatttcact
    38761 gatcagttcc aatgaaatcg tccggatctc ctcaaaacgc tctttatcaa atacatcttt
    38821 tccataatat agaccagctt gagaaagtgc gagtagtctt ttgtattgag ccaacttctt
    38881 gttcattctc ttcccttctt ttttagcaaa tgtatgacta tgtaatcaag tatagaagac
    38941 tggtttaatt acggcaaata aatataatga aatctgcaat aaataaaaga atgttaaaaa
    39001 actcgagaac aaaagacatt cgacttctct ggggctgtga ataaatggcg ttcaaaagct
    39061 tgcatctgcg gtaataagcc ccaccaaacg aaaaatatga cgagctattc ttgtctggct
    39121 gttcttatta attgaggcag gacagctttt tcacaacctc cccactaaac ggtgttctcc
    39181 taccaactcc tcggtcacaa gtcacaatat tcatcaaaca tgagaagctg tttttttgaa
    39241 attgctcctt gtgactcgga gctgaacgac aggctcacga cctctcggta aacagcgttc
    39301 aaaagccaat ttttcgatat taagccattt ctttgttact tattgtcatt gatttctttt
    39361 tctaatttat ccaatagtgg agtgtaatcc acttgagtat agtctgttac atcaaattca
    39421 tatagtgttc ctaactggaa tttgtcatat tttcggtcgg cgatgatctt tttgaatgct
    39481 tctttcgtaa tatgattggt ccctttcgtt cgatcttcca atacgtcacc atagtgataa
    39541 tgatccatga tatagctcaa atgacgatct gattcacgat cacgtttgta ccgacgttgc
    39601 cataacactt caaagtctgc tgttaggcga atcgtgatca cctgatatcc gtatctatct
    39661 gctaattctt ggagtcgtgc tttttgctta tcactaaaag gatactcgga cacaatcact
    39721 ttctttcctg cttccatata caaatcaagt gctttgtaat agaaaggata aactttcgtc
    39781 ctttcttgtt ccgcccgttc ttccaaattg ttaaacccga tggattctgc atagtattcc
    39841 ttgatttcat cgagcgtgat ggcatacata tctggaaatc gttcccgtag tttattcata
    39901 agatatgttt ttcctgtacc aggactacca gccagaagaa tgaaatactt tttcatctca
    39961 tttatttcct aagttaattg gactttccaa gttcataaac agtccaatct tatgcttgac
    40021 aatttctttt actgcttcat ttgctggaat cacattatgg cgaagagact tgttgatttc
    40081 tgtttcacta aaggtttctt tagctacttt cgtccagttg actaaaagct ccgttccaac
    40141 attgaatttg cggatcccgt tattgatcaa ttcaggataa tcttcttctt tcacacctgt
    40201 tcctccatgg ataactaggg ggacatcaac tactgcatcg atttctttca gcaagggaat
    40261 gtttacttct gtttttgatt tgaattgtcc atgattcgta ccgatagcaa tagctaatgc
    40321 atccacgcct gtagcttcta caaatttcac tgcgtcttcc ggtcttgtat ataccttgtc
    40381 attttcagcg acatggattc cttcttctgt accgccgatt gttccaagtt ctccttctac
    40441 ggaaacaccg tgcgcatggg catattctac tactgctttt gtcttcagga tattttcttt
    40501 gaaaggcaga tgggacccat catacatgac agaagtatat ccgctgtcga ttgcttcttt
    40561 gatatcatca aagtctcggg cgtggtctaa gtgcaagact gcatcaacca tttcttcttc
    40621 tgcaatagct gtcattacat tgactaacac atgcatgccg atatatttag cggtatcgac
    40681 acttgtttga ataatgatcg gcgaacccat ttcttttgct gcgcctagca tagcaggaag
    40741 catttctagg ttatgcgtat taaaagctcc aactgtaaaa ttcaactctt ctgctgtttt
    40801 tgttacttct ttcaatgttg tatacatctt ttattgccac cttatctttt tatttgtttc
    40861 ctttgatcgt tacttgtttt gcaatttgtc gcatctcatc cattttgccc atgtagtaat
    40921 cgatcccttg atcatcacca gcacgagcag catctgcacg cttctggtta tagaggctca
    40981 tcagtttttt atacccatct ccgatcgtct gtttattttc caaactcttt tctaaatatt
    41041 ggatggcttg atcgttcaca tacaattcag aaaatttaag tccaacttgt tcataaagtt
    41101 tcgctaattt atgcttatct tgggtagtgg aaatctcttg tttcaattgt gtaatctctg
    41161 attgaatctt ttcggtcgct tctggcgata gggctttttc ttcttttgcc agaacttttt
    41221 tcggttcttt ttcttttttc ttaaaaaatc caaacatcat tttccctact ttcaattaaa
    41281 atgctttcaa aactgggctt aagatccagg catataagag tgctgcggct actgtatcta
    41341 catcggttgc tgtagcattg ttgaatccca tcgaattaaa gatcgttact agcaaagcgg
    41401 gcaataatgt aataaagaaa ccatgagcaa taccgccaat gatcgctcct cggcgtccgc
    41461 caactgcgtt gccaaatatc cctgctgtcc ctccggcaaa gaaattggtt agcataccag
    41521 gtaaaatcat cgctaagccg aacatgggca aagtaaacat ggcaataatc gtaccaatcg
    41581 ttgtcgtaat gaaacctaaa atgacagcat ttgggctata aggaaagaaa actggacaat
    41641 ctaaggcagg gatcgcatca ggaactaatt tcatagctat ccctcgaaat gccggcacga
    41701 tttcacctaa cagtagacgt acaccagcta gcaatacata cacacccact acgaattgga
    41761 tggcttgtaa aaaggcaaac atgatatagt tttgatctcc tgataattca gaagcgaatg
    41821 gttcgcctgc aaataaaaca gtgatgatat atagcgggac catcacgacc atgacagaca
    41881 aataagtatc ttgcagaaat tcgaaatgtg tcggcaactt gatatcttcg atcgactttt
    41941 tattttcgcc tttctcacca aaaagcttag caacaccggc ttcaaataag tacccgatcg
    42001 tacaaaaatg acctaaagca atatcatttg atccagtgat tttacgaatg atcggttgcg
    42061 ctactgccgg catagcaatg gcgaaacaag ctccgataaa accaccgacc aagatcaata
    42121 cgatccctcg cagaccggca aaatagccaa agactgtcgt catcgttgcc atccataaaa
    42181 ttgcttgacc agttaaaaaa atgtacttcc attttgtgaa acgagccaaa ataatattga
    42241 atacaaaaat ggctaagaac gtcagtgcaa tatctctacc taaacccaaa tcattcattg
    42301 cttgaccatt gatagattca atagaaggga tgatcccttg catatgaaat ccttcagtaa
    42361 agattttccc gaaataagtt aaacttccaa cgatgatgct cgaaccggca ctcaacactt
    42421 gaaatcctag gagtgtcttt aacgtgccag agatgacttg tcctgctgat ttcttctgca
    42481 gtagtagacc caacatagca atcaatgcaa tggtgatcga tgcctgagtc aaaatatttt
    42541 cgatgataaa attgataacg cccatgtttt taccctcttt tctttttgta tttagataac
    42601 tcccttatct tgcagaactg gggtgatttt ttcttcaatt tcattttttg aaacaatatt
    42661 tttcaaatag atcatcgccg ttttaggatc aactgcgaac ttttcgaact gcgaacgaaa
    42721 attttctgct gtgatgatca catctggttt catggaaact gcggaagaaa tatcacaatg
    42781 gtccagtttg gcttctactc ctaatttgtt caaaacatcc tcagcagaca tctgtgctgc
    42841 aaaactactt cctaaacctg caccgcatac gaataaaatg ttcaatttgt tcatctttgt
    42901 tctcccccgt atcatttatt atttctcaac tactgaaaaa agcagttgtt tgaaatcttc
    42961 gatatttgtg cattcaatca atcgatccaa cttctcttcg ttgttgatca attcaattag
    43021 ttctttcatg atgttcagat gcgagtagga gtctactgct gccaaacaaa aaataatctt
    43081 tactggatcc atttcaggat taccgaaatc gattggttgc tcaatcgtag ctacgctgac
    43141 tcctaattta ttgaccccat cttctggtcg ggcatgggct agtgccatgt gtttgccaat
    43201 cacgatatac ggtccgtaat cattcactgc acgaatcatc gcttcgacat agcgctcttc
    43261 gacaatgttt tctttaacca atggtctagc agctagttca atcgattcct cccaagtagt
    43321 ggctttttct ttgatcatga tattgctgtc cgtcaaaata tcttttaaca taggctggat
    43381 ctcccttttg ttgatttcta aattgtttgt ttcgaataat ttttctaact tgccatagat
    43441 gattcgatct actcggccac cactttcttt catgacatct attatttgag tgaataactc
    43501 cgtcgattca tgactgttag gctctaaccg ctgtagttct tcatttcttt tcaaaaagtc
    43561 ttctataacc aagatattcg tctcagttaa aatcggatcg acaactaaaa gcggcttatt
    43621 tcgataattc aattgaaagg tgctgaaaac cagattgaca tccaatttat ctactaattc
    43681 gatttctttt gaacttaaaa ctgcagtaat ctcgatctga ggaaactttt ctttcagatt
    43741 ctctgctaac agatttccag tagccatccc atggttacag acaacgactg atttataaac
    43801 ataattcaag tctcgcttga ttacactggc gatcgtcgaa aagtggatga caagaaaagc
    43861 tatctcgtcc tccagtatct tgccaccaat tacttcttcg atcgtaggaa caaaatgagt
    43921 gactgcgcgg tagattggga aataatttgt tcggatgttt tctttcaatg gattcatgac
    43981 ttggatatga ttcttgattc ttacaatcag tgcagccatg tgcttataga gattttcgaa
    44041 taaagcttct tcctttagat ggaaaggtac gtgtgtctcg ttctctacaa attggatcaa
    44101 ttggatcgtt agtaattgag cttgtaccca ctcgattgaa ttggagatat ctctagcatt
    44161 gaacgtctca atagtgaaac gaagataatt tctttctact tgcgggacat tgtccaattg
    44221 aaattcctcg atcatgtggt caataaatgc agaaaagcta ctgtctttta tttctgtatt
    44281 tttccaatta atggcagaga taaattcatg tttcctgatt cgctggatcc agatcaatgt
    44341 aaaaagcagg atttgttttt tataaatatc atcttcttgt ttcaacaact tattggaata
    44401 gatctcctgt atttttttga tttccaccaa aggaaaataa tggagaaaga ttttttgagc
    44461 cggtgttaat tgtgcatctt gattcataaa gaagtcggtc attcccagat tctgattgat
    44521 aaaatcatag atcatcgtac ggatagatcg ttctgaacct ttataaacca gtccttgctt
    44581 tccataactg acgatctcta tcccataact gaccagtgtt gctcgtaacc gtctcatatc
    44641 ttcatctaat gtacttttag agatttgaaa ttcttcttct tttttgttta gatggatcgg
    44701 gattcggctg taagcaacgg ctaaaactag atcaaaaata cgttcgcgcc gattcaaaaa
    44761 gccgtctttc acatctttta tttcagtttc taatcgagct tgcttttcct tttccagctt
    44821 caacaaaaaa cctttgttgc gaattgtacg gatctccgga agctttttac tgctcaacca
    44881 gatattcgct tcaagaactt cctgacggat cgtccgctga ctgacattga actcacttgc
    44941 tagatgtttt gcttttactg gatattgggc tgtcatgatt ctgtgaagta tttcaattgt
    45001 tcttgttttc atagaaatga tctccttctg atttcaagta tatggttccg cttacataat
    45061 aaaaagtaga tatttctgcc acttgaagtg gaaagaaagt aagcaaagca aacaaaaaat
    45121 aagccatatg ctttttcatc tcctcaacga aaaagacata cgcctattat tacaaaaatt
    45181 ttgcccatct atacaaaaaa gaggttgtga aaaagctgtc ctgcatcaag taataagaac
    45241 aactaaacta aaatagtgct tcctattttt cgtttggttg ttcttattat cgcagatgca
    45301 agcttttaaa caccatttag tggagaggtt gtgacagaga tgttcagcct tgagcgataa
    45361 gaagcgattt tgaaaaatcg cttcccatat tttacaaaat cgtgccttat tgccgatagg
    45421 ctatctctgg cacaccgttt attcagaaaa aggagctgcg acaaggcttt tgtcacaact
    45481 ccgttcataa atatttcctg tcaatccagc ataatcggct gaataaaatc ggcttgccat
    45541 cttttttctt tctcagaaaa atcaaaatac catatctgag aaaaatactg tcgttgtgtc
    45601 ttacttcctg agatcaatcg cccatctttt cgatcgactg aataatcaca gcatctgaaa
    45661 tcaattcgga tggcaaaact attttcgtgg atctgtcgat aatttcctac ttcctgaata
    45721 gttatttttt tagtatgatt tcttacaccg tctgctttgt ttttttgcag aactttctga
    45781 tgttcggcaa acagcttgtc tgtataacag cttctggctt tttcaggagt ttcttcttcc
    45841 caagcggatt ggatcttcat gaatatcttt tggatttcca gaaactgtgc tttcttttct
    45901 ttagccgttc ctgacatgcg ggacaatatc tccgctttca gccttttctt ttgtctttta
    45961 ttcttgacga tagaaaaagc agaaacccct cctactgaca aaacagctaa tgcaagaaat
    46021 cccgtttgct cataactaga aggacctgta cctggaccat aatacccata agaatctctg
    46081 ccgtaagaac gactgccaaa ataactgccc ccatatgaac gaccaccaaa tgaacctctg
    46141 cccgaacttc gaccgctaga tgtacctcca ccatgaccac ccgcgacagc gaatccttgg
    46201 gtcggcagag caaacaaaca taggcccact aacaaaatga ttgctaaata attgattttt
    46261 ttcattgtct tcctcgttat cttttattac aaaaaactat ttttatgata gccttgctaa
    46321 aaggaagagt caataaccag atgcataaac tgttttttta gcaattttgt cttatttagt
    46381 cattgagtaa catcggacaa atgtatgtgt cggcagtcca taattcctct atcttcagca
    46441 tgaacaagct tgcagacaag agatctgcgc ttcctccagg agagatttgg ttttcctgac
    46501 aaaagtgcaa cagtgctgta aatggacgat ttggtaaagc actttgacta gcagcatgag
    46561 caagtttttg catttccact aacgttttct gatcactgcg atgcaatacg catgtgtcat
    46621 ctagcgaact catcaaaact aacaacatat gcatttgttt ctgtacatat gaatcattat
    46681 ctagctcctt agctgcttga attgcaagcc tgatatgcgg ataccctaat atcgcttctt
    46741 catatgcacc atttacgcca tatttttgct tcaccctatg accatgagtg gtttttttat
    46801 gacgatattt tgtatcagga aaagcagcaa gcttgctgac atcatcaagt attttcgata
    46861 aagaaaaagg ctgttccata ctgatttttt gtgcaatgac actgatcaat agccccattg
    46921 cccaaatcgc tcctttatgg gtattgatgc catttgtagc aatcagcatt gccttttccg
    46981 cttttcgccc aatctcagca attctttctc ttaactcctg atcaatagca tgatgccatg
    47041 ctatttgagc catttcttca aaaaaaggag ttagcgtctt agcagactta agaaataaag
    47101 catagtccat atcggaatgt gcacccgcat ccagtgcatc cactaatcca ggttttggac
    47161 ttaatgttac ttctgcgatc aatgcttcct ctaccaacgc agcgagttgc tgagtcactg
    47221 ctttttttcg ttcgtcattt atcatgacac tcactccttc ttcctactat tacttgctga
    47281 aacctttttt gatagctacc caaatgatat gaagtaacca gcttaaagca aatgcacaac
    47341 ttgccgtcat tagataagct acaagaatca tgactcctga aggtaactgc agccaactat
    47401 ctttaaacaa taataacagt acttggaaaa caaatacatt ggctaaatac gtacgataag
    47461 cataaacaga caaccatttg aacaatggca attttggcga atcgtttaca atcattttgg
    47521 aagcgcctat gaagacagca aagatgatga ctaaactgta taaactttgg atcgtattca
    47581 agtaaggtgc attcgcaaag ctcaagtctc ctggatgtgc gagcaatgaa cggacagaaa
    47641 agaacgcgat aactaaggca acaggtaaga aaagataacg tactctgtcc aaatattgat
    47701 agactttttc gtgataaaca aatgcggcta ccccataaat catgaaacta gcaacaaacc
    47761 gatctaataa gtaccagctg tcatgataag gcccagtcaa tacttgtgtt tgatagaaca
    47821 gataccatgc gacatataaa atcgttgaac caatcaatac tggccataca tattttttat
    47881 tagcaaatac tttgtaaccg agccaaacaa aaaacggcat gaacaattgg atctgcagca
    47941 tcataacggt ataccataaa tgaggcgctc catcacctgt gacatatttc agtaaaaagc
    48001 ttgcagtatc cgtatacgga gtttgttgtt ggactgctgg aaatagccaa agataagccg
    48061 tcgtccatag aagatacgga acgactagtt caaaaaactt ttctttcaaa aattcccaat
    48121 aagacaaatg ctgacttgtt tttaccatat tataaacaat tgcaaaaata aacattggtg
    48181 ctgtgtattt aacgatgacg taaaaggtac caagaaaagc tgtatttgtt gcgctgtggc
    48241 tgtttgccaa agcaaagctc aatatcgttt gcatcataac agccgttaca gctgatactt
    48301 tctggaagtc acttacgttg attttgattt ttttgttttc aaacatctct ttctctctct
    48361 ttttctttat taccaaagtt ctttggttaa tttaggtcct tcgactgttt tcaatagaat
    48421 ttttttctct ggctctctca aatactcttt tagtgaaaaa ccgccttgcc gagtcactac
    48481 ttgggtatcg aattgctcaa aaaaagcagg atgcgattga attacctgaa ttggcaattc
    48541 aatcggtgaa tttgcgtaca gcagcaaatc aaaatcactg gtttctttta ctgccggaat
    48601 cccagtcgat aattcaaatc ctaagctgcc gccgattccc catttacatc ctgataatat
    48661 gtttctagca gcatgaaatt gctgataaac aggataatcc atgattttct cttgtctata
    48721 cgattcttgt tcgatgatgt cccacggatg aatgacttgt ttgacggcat gttttgagat
    48781 ttctgttgac catctctgat tgcgggcagg tccacgtaaa ccaatcggta gtatttctgc
    48841 gtgatccgtc gacgcacgac gaactgttcc gaacatcttt tcagttagaa cgacccattc
    48901 aggcaaggtg aacccttcta tttcatgttt atcaaaaagg acaatatcat gtgcttgaat
    48961 cattttttat gcatcccatt cttcgtccat tttggcacgg actttatttg tttcgacacg
    49021 tccgaatgtt ttggctgttt cgtttgtgta tcgatttgtc agcatcgtgt catttgtatt
    49081 gcggacatct tgaatggctt cattgattgc ttcgatgact ttgctgacat tttgttctga
    49141 agcagcttgg tcggtgatat cttctaggaa atgatagatc gctcctagtt ttgtataatt
    49201 attgatatcg taagcgatag ctggaacttt ttcagcagct gcttcgattt cagcaaccga
    49261 acgttttgtc acacgtgcag cactttcttt agacatcgct tggacggtaa tttctttatt
    49321 gtttaaagca atcaagcggc ttgattgtaa tccatgtgct aaaaatgcac ctgaaatagc
    49381 atttcctgca atcaatccaa taactggatg tccagcttga cggagttttg cataagcagc
    49441 agcactatta gccaaagcca catggatacc gatcaattct tcgttatagc cgtatgcttg
    49501 gcttggtaca tcgatcacaa cgatgattgg ccgtttcact tttttgtctt tatcttcttc
    49561 gtaaacgtga tccaaaattt gtcccatgcg gaaaccttca actaaaccaa cttcaccgtt
    49621 tcgtacacgg tacatcgggt ttttaggatc aggtacgatt gatgtcacga tggcttcttc
    49681 tatgaattta cttgatttac cataatacac agtactaata gaagaagttg gatttttcat
    49741 gccagttagt gccgcaaacc aatcgtaacc aacacttgct gcagctggtt catttccttc
    49801 tgctacttct ggtaagtcaa ttgattttgc ttgatggtta gcaattgctt cattgtaatc
    49861 gtcaatggcc attggttttg aaagatctaa agaatcaagt aatgataaat aaaatgctga
    49921 gctttcactg cgatgcgtgt cttttcgttc gtccattgct gcgatgacag cagctttgat
    49981 tgcttctaca ctatcagtca ctaattcatc aatgattttt gattctaccc gttgacgaga
    50041 tcctaatgta ttccaaatca agtctttgtc actagaatca aattctcgaa cgcctgcttc
    50101 ttgttcaata acttctggtc cattcaaacc gactctcgct ttttttgttg cgattaaata
    50161 actcattaat gctgaagtaa tcgacatacc gccaaatgat cctacacgtc ctggaatcaa
    50221 accgatgact ggtacatatt gttttagagc aatgattaca tttccgattt ctgaaataga
    50281 taacagtccg tagtttgctt cttgcaaacg aacaccacct gtatctagta caatgactgg
    50341 aaagatctca tttccttttt tattttcttc taacacatgt tcaagtgcag caacgatttt
    50401 tgcaccggaa acttcaccga taccgccacc ttggaatttt ccttccatag cgattactac
    50461 tgcttgtttg ccattgatcg tgccacggct gacaacgatc ccgtcatcac tttcagggac
    50521 gattccttgt gctggtaaac ttggcgcgat gatttgatcg aatggatcaa tcaattcacg
    50581 tccattgtca agtagagcgt tcactcgttc tctggcgttt aattctacaa aactattttt
    50641 catctgaaag ttcctccatt gcttgcgtca atcgtaggta cacaactcct ggtgtagcac
    50701 cgaagtcatt gatcacgata tctgctgaaa ttggataacg atcaaaaaat ctcgttaata
    50761 cattgttcca tacttcgccg aagccatcgc ttcctgtaca aatttttaca gtagattctg
    50821 ttttttctgt tggaaacatc aagatttcca aatctcctga accgaccact cctacatgga
    50881 ttttcttatt gatcggctgt ttcgttggat atttataagc taattgttcc atggatctct
    50941 cccctttttg taaaacagag catacacgtt ctgcttattc gtctttcttc ttccatctgg
    51001 gtaaatggcg acaaaaggtt tttctcgcca attttatgac caagttctga atttcattgg
    51061 tggttcatac aggccatctg accattcgat caaatcatcg atggtttgtg cagctaataa
    51121 tgaacgtttc gcttcactac gtttgatgcc tagatcttct ggtaatttca cgatgccggc
    51181 tgcacgcaag ctatctagtg attctttcgt gctagtcatt ccaagaggtg taacaccgcc
    51241 aattgctgca attgctgctt gtcgttcttc ttttgttttt gctttgtaca aataagcaat
    51301 tccttcttct gtcacgatat gtgtagtatc ttcgctataa atcatcactg gtgcattggc
    51361 taagcctgct tgtttttgaa cagctagtgc atctaattct tcgacaaaga ctggtttttt
    51421 atttgaacca tatgtttcaa ccatttgaac aactaatttt tggcctttcc ctaatggatc
    51481 atcattgtcg cgaagtgatt gccatgctgg tgtagaatga cgacgaccgc caggattatg
    51541 tcccatgtta ggcgcaccgc caaaaccaga taaacgtcct tttgttacgg tagaagagtt
    51601 tccttcgtaa tctaattgca aggttgaacc gataaacata tcgatggcat attgtcctgc
    51661 agcttgtgat aatgttcggt tactgcgcat cgtgccgtct ttaccgacaa aaaagacatc
    51721 tgggcgagca gcaatatatt tttccatacc aacttcgcca ccaaaactat ggatgctttc
    51781 aacccaacct gattcgatgg ctggaatcat cgttggatgt gggttcaata cccagttctt
    51841 cgcgattttc ccttttaacc ctagtgattc accataagtt ggcagtaaca attcgatagc
    51901 tgctgtattg aatccaatac cgtgattcaa agattgtacg ccgtgttctg cgtagattcc
    51961 tttgattgcc atcattgcca ttagaatttg caattctgtg atgttttgag gatctcgtgt
    52021 gaataaagct tctaattgat aaggtttatc tgctttcacg acaacgtcta cccagtcacc
    52081 agggatatct acacgtggta aagaatcgac aacttcgtta acttgaacga tcacgatacc
    52141 atctttgaaa gctgcagctt cgatgattgt tggtgtttct tccgtattga aacctgtgta
    52201 caagttgccg tctttatctg ctttatctgc agctactaaa acaacatttg gaatcaaatc
    52261 gatgaataag cgtccataaa gttccaaata agtatggata tcacctaatt tcattgtgcc
    52321 gtcttcaatc atttgggcga cacgcaagct ttgtgcacca gcataagaga aatcgatctt
    52381 gcttgcgatt cctttttcaa aaatattcaa atgttctggt cgtgagatac tagacatgat
    52441 caaatgcaga tcattcactt tttctgcatc tactttttca agactttctg aaagaaaact
    52501 tgcttgtttt tgattgtcgc cttctaatac aactttgtcg ccgggagcaa tcagtttttc
    52561 cattacttct acgatttttt cagtttctac atacttgcca ttgagcaagt tgctgatttt
    52621 ttccaatcgc tgcgcttttt tttcgcgttt agaagcccag ttgcggtttg gtttttccat
    52681 aattagtcat ctccattttt gatatagaaa cgtggcgtca tcaataccat gttggtctag
    52741 attgatcgta cggatccctt tatctacacc aaattttgta tgaatcagct ttgtcaaagt
    52801 attgccgggg ggaaattcaa tcgtcagatc cattcctaat tcttttgcca agtccatcat
    52861 ttggttccac tgcacaggga aagctaggtt ttccaacaaa tctttacgaa tctcttctgc
    52921 gtcctgagtg gctcttccat ccgtattttt tatatacaaa catctagcat cagatagatg
    52981 gacagactgc atatacggct tgaatttctt gaccgtatca ttcatcaaga gacagtgaga
    53041 tggcacaggg actttcagca gcttcgctgt ttgcgcttgg tgccgtttgg cttctgccaa
    53101 cgtaacggat aaaccttcga tactcccaga taacgtatgt tgcatcggac aattttcatt
    53161 tgacagataa actggatggt caggatcaaa tgtttttgct acaatttcct cagcttcgct
    53221 tctcgtcaca cctactacta cgcccattgc ataaccgctt ggataagctt ctttcattaa
    53281 gactgcgcgg tgatagacta gttccgctgc attctcaaat ctcaaagatc gacaagcaac
    53341 agctgcacaa aaagcaccaa tcgaatgtcc tgctgcaata tcaggctgaa taccgttttt
    53401 ttccatttca tctaaataaa atactgcttt tgtcagtaat gctagctgga taaaaaccgt
    53461 atcttgatag ttttcttctt tatcaactaa ccgatacccc gtcacatttt ctaaacgttc
    53521 catgtacatt tcagggatat ccgctaacat ccctaacttc tgactgcctt gtccaggaaa
    53581 taagaaacct gtactcatga gcctcgcctc ctcagcactt actttttcca ctgctatctt
    53641 agtcaatttc tgctataata aaaaatgcca aaaaaagaaa aaaccataac aaaaaggtat
    53701 ggatgggatg gataattatg aaattgcttc atctgcagta ttttaaaaaa gtattcgaaa
    53761 caaaaaatgt tacccaagca gccaaagaat tatttatttc tcaacctgcc ttgagccgtg
    53821 cgatcaaaca tttggaaaac gaattaggtg tccctttgtt ttaccatagc ggcagaaaca
    53881 ttgagacgac cgtttatgca gaagaatttt atccatatgc agtcaagaca ttagacacat
    53941 tagaagaagg aatcaaatta ttgtcttcgg tcaatgagaa gatcgttact tccgtcatat
    54001 tgtatttaga ggtagcctct gtttctattc cgaacttggt ccgaattttt atggaaaagc
    54061 atcctgatat ccaattaacg atcatgcaac atcatttacc agatgatatt accgatcctg
    54121 tactgtacat cacttcggag atgaagcctg gcatgaccaa tattcctatc atgaaagaac
    54181 ctgtttatgt cgccattcct aagaaacatc ctcttgctaa aaaagaacat ctgcaattag
    54241 aagatatcca acgcaccccc atcttgatgc tgtcaaagag caacgccttc cgtcatacac
    54301 tggatgcagc acttgaagcg aaaagtatcg aattgacgat cagttcgacg acagatgatc
    54361 ctgcgacatt acgttctatt gtcaagcaag gattagctgt tagctttttc ccaaaagttt
    54421 cttggtctta cgataaaaat gatcctttcg tcttgcggga aatcaaagat ttgcccttga
    54481 cacgaacaat ttatttatct tctagcttca cagaagatca tcctttgatc aaaatgattg
    54541 caaaaacgat gcgggaattt tatttaggaa aataaaaaaa aaagagctgg gacaaaattc
    54601 ttgtcgcagc tcttttttcg aacaaacggt gttccagaag taatttctta gaaaataagc
    54661 cgaaatttcc caaaaatttg agaagcaatt ttcgtaaatt ccttcttatt tcttgaagct
    54721 aaacatttct gtcacaacct cttctctatt gtcctagaca ttcattgcgt tgatttaaaa
    54781 cttccatcaa tcaaatctgc tagttcatct agcttttcta ttttacgtag atcaatagag
    54841 atccaatgtt ctttattcat gtgataggct ggaaaatacc cctcttttcc tcgcaaaatt
    54901 ccgccaagtt caggatcgac cttcaaatca agaatattga tgatcctatg gtcacttgca
    54961 tcatcataga ttttttcttc tggaacagac atcaggaccc caaaccattt tttgcttttt
    55021 tgatgtctga atacgcaata atcaggaaat tttttaaaaa tatattctgg agacaaattg
    55081 tatgtttcat tgatgtgatc gattagttct tttttcgtta gcatctgctt ccatctcttt
    55141 cttattgatt cgctttattc aaagatacca cgtaagaata gaaaaatgaa tacaagtagt
    55201 tgctaatcaa atacttcgat atttttcttt tttatcaact cttaaatgtt caatccgcct
    55261 gtgttggtct tgctaccatc tactattaaa atgtttatta ttgtttgccc acctattttt
    55321 tgattttagt ggtatcattt ttcaagttca tgatgaaatt cttatcatca gtaaatgctc
    55381 cagaaaaata aacaatgatt gaaaaatcag ttgaaacttg accaccgttt attttctccg
    55441 tattcttaga atagaaggga gtctgattga tgtattcact aatgaaaaaa atcattaccg
    55501 aaaaagatat tcgacgtcat gtttctttag tagaacaatt gctgaatcat acaaagataa
    55561 ccgtaaatga attagctgaa atcataggga caaccgaacg aacgattttt tctgaccttc
    55621 aatctattcg ctctcagctg cccgaaggct gggacatcat cagcgatcaa gcaggaatca
    55681 gtttgcaaaa ccagcaaaat ttattaacaa atgacctttg ggagattttt ttcaaacaat
    55741 cagtcagtgt cgaactgctg aaaaatctgc tttttacaaa aaaagttgct gtccctgatt
    55801 ttctagccga ccatgggctt tcttatggga cattgaaaag acatgtgact aaaatcaatc
    55861 agcgtttagc aagttacgac ttgcagatcg atttgacgaa atatacagct tgtattcttg
    55921 gaaaagagcg tgcgattcgt actttttatc atcgattgct gattcctttc actcataaca
    55981 actatttttt cgaggattat tcgatccatg aatcccatta ttttcaattt ttaagaaacc
    56041 tcagtcaaac tgaactagcg gttgaaacag aagagatttt cggaacatgt tggttcttta
    56101 tcaatacgat ccgtataaaa gcgaattgcc gattagattc ttctatccat accaacagca
    56161 cactctcctc cctgtatgac tctgcattga aaaaattgta tttaacggaa ggtatttatc
    56221 ttaaagacac tgagctttct tttgcttctt tctgctttct ggaaagttgg aattacaaca
    56281 ataactatgg acaagaaacc gctcgctgcc tgcatcattc tccattttta gaggtcctcg
    56341 aaacgtttgt agaggaacta gcttcagagc tgtctcttga tcaactaaaa aaaacatctc
    56401 tgactgataa cttggctctc ctcatattaa aatatcatga atcgccgata ttgattgaag
    56461 cattggaccg tcaataccat cgttttttag aaacatatga tcagcaatat gcacacttgt
    56521 atcaacagaa agagaattta ctgaacgatc taaaaaaaga aatagaaatc aatgaaccaa
    56581 attactttct ccaactcttg tctctactga tccaacaaac gattttttct atcaaaccga
    56641 atttgttcaa tgtctatttt attttccaag gagaaccttc atggaaggcg ttcttgcagc
    56701 aggaattaaa agattactta ggaaaacgtg tctgcttctt acctatcgaa ctaaccgatc
    56761 tttccactat ttcttttgaa aaaacagata tcttgatttc caatttccct ctagattctc
    56821 tagatatccc tattgtatac atttcttcta ttccaacgaa aaatgagctc aatcgtttga
    56881 ctgaactcac tttcaaaact tttttatagt aacggctagc gactgtattc tctagctgtt
    56941 ttttcttttt tgcgaaacag tttgttcatg atcccttttt ctatttctac aactaagaat
    57001 agaagaatca catttgctcc aatcaataac tgttgtgtca tcgttaaact tactgtaccg
    57061 atcagctgct ggccgactgg tagaaaaata accatccctt gcaataaagc aaggatacct
    57121 aatgaaagaa aaagcgcttt gttttgcaaa agaccttggt tcaatgacgg cttggacaac
    57181 tctctgcaat tgatcatgta aacagcttga gctaagacga tattttgcag aagaatggtt
    57241 tgctgtaagc tttgcccttc aaactgcata gccaataaat aggcaggaac catgatcagt
    57301 agggagacat agatgatccg aaacaaatga taaccagata ggattccttg ctttggatct
    57361 cttggtgggc gcttcatgat ttctggatct ggcgactcga accctagtgc ataagataaa
    57421 gtgattgtcg ttaccatatt gacccataaa atctgtactg gggacaaagg tagcgggcga
    57481 ttcagcataa gtgcccaaat caagatcaat ccttgagcta atgcagttgg caagaagaaa
    57541 ttgatggttt tttgcaaatt atccaaaatc cgccggccct cttttacggc ttttgcaatc
    57601 gtatggaaat tatcatctcc taaaaccata tcagctgcct gtttgcttac ttcactacct
    57661 ttgattccca tagcaattcc tacatcggat cttttcaaag caggtgcatc atttacgccg
    57721 tctccggtca ttccgacgat ttctccattt ttctgcaaag ctttaacaat tcgcagttta
    57781 tgttctggtg tcgttcgagc aaagacatcg actattggca cttgctgaat caactcttca
    57841 tcagacataa gatccaaatc gatcccttct aaaactttgg cagtatgttt taagccaatt
    57901 tgttccgcaa tcgcttttgc tgtgtctttg tgatcccctg taatcatttt cactgagatc
    57961 cctgcttgtt ggcattcctt tacagctttg actgcacttt cttttggcgg atcgatcaat
    58021 ccggcgatcc ctgcaaaagt taattgggtt aaagtctcat gcgtgagttc ctgtttcgaa
    58081 tctacttttt tataagcaaa tcctaaaaca cgctgacctt ttctcgcaaa ttctgcagct
    58141 gtctgactcc atgcttcttg ttctgcagaa gaaagagttg atttagcaaa taatacttct
    58201 ggtgcacctt tgacgtaaat caccgctcct ttttcctccg catgcatcgt tgccatatat
    58261 ttgtattcag aactgaacgg aatctttgct tctatttttt tcaaaggtag attggctgtt
    58321 tctgtgtgtc gaatcagcgc aacttctgtc ggattgccac ttaaattttc tgttttctgt
    58381 tcttcttttg tttttaattc ctgacagttt ttcataatgg acaacacgca ggcttcttct
    58441 tttgcagcta catccacaac tgtcatttca ttttttgtca atgttcctgt cttatctgaa
    58501 cagatcactg tcatagaacc taatgtttct accgaaggaa gtcctttgat gatcgccttt
    58561 tcttttgcca tttcatgtac tccaacggat agaatcatgg tcaaaacagc tggcaatcct
    58621 tcgggtacca ttgacaccac caaagcaatc gtagccgaaa gaagaatatg ccaatccata
    58681 ccatatcgaa atgtcgtaaa aataactaag aataggctca aacaaagaat gccttgaaaa
    58741 atttgtttgt ttaatcggtt gattttttta atcagaggcg tcgtttgttg ttcgaccgat
    58801 tgcaatgctt gattgatttt accgatttct gtcgtgtttc ctgtttctac aacgacaccg
    58861 actgcagaac cagattgtac aagcgttcct gaaaaaccca tatttttctg gtcgccgatc
    58921 gattcttctt ctgtcaaaac ggcatgactt ttttcagatg cttctgattc tcccgtcaaa
    58981 atcgattctt ccactaataa atcatgtgct tcgattaatc ggatatctgc tggaacgaca
    59041 tctccggcac gtaagacaat gacatctcct tttaccagtt ctttcgcagg gattttttct
    59101 tgcatcccgt ttgatagtac tatcgcttct tgtcccatca gctgcttcaa accattcaat
    59161 gattcttccg cttttctttc ttgccagtaa ctaacgagtc cattgacgat cactacgaat
    59221 aaaataatac ttccttcaat atattcacta gaagcaaatt tcaaaaaaga ggcaatgatc
    59281 aacacgatca tcagcagatc agtaaaatgc tttgctattt ttttccatcg ttttgtctgc
    59341 tgccttgctt ttatttcatt atatccttga tcagtcaggc gtttctgtcg ttcttcttgc
    59401 gacaagcctt ctgttgatgt ttgatagttt ttcaatacat cttctaccgt caatctgtac
    59461 cagttcatcc tatcccctcc tgtttaattg atactgttat tatacgcagg gaagtttttt
    59521 caggcgtatc gattatttca ggggggtctg aaataattcg ttttgcaaaa tgtatctggg
    59581 cctaactgat atttctattg cttattcttt tatatacaaa atttaagaat acaaaccaga
    59641 taaccaataa aaaaggaata aagcgtgtcg tgctttcgaa taacaagctg aaagcaattg
    59701 aagtaaaaaa caccaacaaa gcaagatctt tatatctttg tgtagtgttc cgtttctttt
    59761 ctttaataaa ttgaacatgt gcacacaaga tcgaagacca cacaaataga aaacaactcg
    59821 ttgtcatgcc tgccaaaagc tgaaaaaaca atcgactatc agctacaaaa aaatgtagac
    59881 aaagaccggc aaaaaataac attcctgtaa ttaaaatacc gtgtaaaggt acgcctttct
    59941 tagaaagcgc acaaaaccaa tggggcaaac ttttttcttt tgctgtttga tataaaatcc
    60001 tgctagtact gtagactgca ctatttgctg aggacaaaga agcaaccaaa atcattagat
    60061 tgacaattgc tgctccgcct tggcaatgga tcacttgcag catagtcact aaaggacttt
    60121 cttttaaatc taaacaatgc catggaacaa caaataaaat cgacaaaatc gttcctatat
    60181 agaaaaagag aatacgccaa ggcagacagt tgattgcttt tttcaaattc ttttgcggat
    60241 cacttgtctc gccaacggtt aagccgatca tttcaattcc agcaaaactg aataaaacca
    60301 taggaaatga gactaccatt ccagcaaagc caaacggtag taattcatcg atctgtccaa
    60361 aattttcttt gattccgata gactgggtat gaaaatctga gacactcaat cctataccca
    60421 ataagataaa aaggaaaatc cccaagatct tgatgattga gaaaaaagat tccaattcac
    60481 caaaccactt gactgcaaca aggttgactg ccattaagat cattagtgcg ctacctccgc
    60541 ttatcaaagc tggtacatgt acaaaccaga aatggatata caatcctatt gctgttaatt
    60601 ccgcaagtcc agctccaagc cagcaaagcc aataagtcca attgacaaaa aatgcccact
    60661 ttttgcctaa ataatagtca acgaaatcac tgatagagtt aaatgtacta tttgctaaaa
    60721 ataaatcacc catggcccgc atcaaaccat aaatagccaa accgcatatc aaataaacga
    60781 gaataacagc tggccctgct gatgcaattg cctttgctga acctaaaaat aatcctgttc
    60841 caattgcgcc acctaatgcg attaactgga tatttcgatt agttagagtc cgtttcattg
    60901 ccggtttttc catcaagttc acctttttct ttttcaagca gcatggcgac ttcctgttcc
    60961 caagaaggtt tctttatttt ttcaatacag agtggtacta caaacaaaat gacactgatg
    61021 gctgtgactg caattagatt gatccatgtt ccagctttca tcgtcagtcc gacagaaaat
    61081 ccgattgccg caaataaaac aataacgaca gtccaaactc caagattgct ctttttctct
    61141 ttttttccaa ttctaaatgg tcgattcaac tttgcatgtg tataacgcaa tctcaaaact
    61201 gcgatcccca tgatgacata gacgatacag tagataacag tagttgaatt tacgagcatc
    61261 aaaaatgctt gattgacgcc aggaatcagc aaataaaaaa gtgcaaagat tgagataatg
    61321 acagactgag tcaaaataac ggatttggat acgtcaaatt gattcgtctt ccaaaaattg
    61381 aattttggtg gatacgcacc ttttctagca ctttctgtca ctgtctttgc tggtcctgag
    61441 gcccaagcag ataattggac tgctacacca atgaagacaa gtaaactaaa cagattcaca
    61501 ataagatgtg gcaaaccaag aatttggcaa taaatcgaaa tagattgcgc gatattattc
    61561 aattccattt gtccttttgg tacgacattt gctacaacta aagcattcaa aatattgacg
    61621 aaaaatataa aaattaacgc ggcaaatact ccgcgaatat acgttttaac tggattttcc
    61681 aatcgagtga tatacacaga ggacatttcg ataccagtaa aaataaacat gatcggcgca
    61741 aaataaacaa atgaggatgc agtcgtagta tctggtatta atttgtccca tgaaaaactg
    61801 cctaatgttc cggttggtac gatcccaact ttgatccacg cagcaaaccc taataagagc
    61861 atcatcgtca aaggcacgta caatcctaac caaacaccga cttttccgcc gatttttgcc
    61921 atatcaaatt tcaaattcaa aaaagtgatg atccaataaa cgactaaaat gacaactaat
    61981 gtaaatttgc tgttcaaacc aagcggcaca ttatcgataa tattaccaaa caacggagcg
    62041 agtgctgaag cgaccatcac catcccagga aacatttgga cccataacag ccatgagaca
    62101 acgaaccccc atttttttcc tagagcattc gatacccaaa gttctggacc acctttttgg
    62161 ggaaacattc cagcaaattc accagagatc aatgagattg gaaaagcgta caataatact
    62221 gcaaccagca tgtaaaaaat catcgtccag ctcgttgctg ctacatctgg aatatttcgt
    62281 acacttgcta caagggcgca ggtcattccg ataaaggtca tggtcgtgat ttgctttgat
    62341 gaaccagtat ctttcatctt tattccttct ttcaatagcg acatatgttt ttgttttctt
    62401 ttatttttgt tcaagaacag aaatgacaag gtttcatcga ttcagtacaa aacccagtat
    62461 caccgaaaca tccattgaac gatcttagtg aactgggttt gatacatgaa acgaacgatc
    62521 caacttatag aacgttttat aaaaaagaat atcttggcga ggaatatatg aaaaacaggg
    62581 ggaaatacaa ttgttttgat gaagcaaata attgtctgtt ctccatatgt ctcttgttat
    62641 tctttcacac aaaaatcagt tctattggat gatttcgttt agtttctttt ccattgcttt
    62701 ggcgattttt tttgtataaa aattgaaaat tcgatcatca ttcaaataag gagtcatgat
    62761 agccgcacgt agcagagtga ttttctgttc ttttttccat tcttctttcg ttagacccat
    62821 tctttcaaca aaacgaatcg gagaatcacc gtaatcttct tgtgtaaatg tagtatgaga
    62881 agtaataaac cgttcaccat aaacatcgcc atccatataa gaagaccgat cgaacatttt
    62941 ttcatttaat tcattgatag cgttcaaatc tgtacagcct tgttctttga atacccaatt
    63001 gaccatatta aaatcaggat gattcaatgg atagacttcg attgtttttc ctttaacagt
    63061 aaaagtcaga tgatcgagaa attctctgaa tctttgagct gcctcgattg aagccccaat
    63121 caattgacca tatccggtca cattcaatgg caatacacga tgtgctgtcc agactgcggc
    63181 ggcggttgct ccagcttttg atccttccaa aatataagct cctaacatat ctggagcctt
    63241 tactgatttt tcaaacacat atggcgcgaa ataagaaatg atatttctca tatttttatg
    63301 tttgattacg attcctccag cagcataagg gacatagccc atcttatgag gatctatcgt
    63361 gacagaatcc gcttctgaaa tagctctgaa cccttcatat acctctttgt caatcgttac
    63421 gcagtggtgg aaaacatgat gttcttcaaa gaattcagct aaggaagcat acggcacaaa
    63481 ttctcctgct tcgtttagaa acagtgaacg cgcatagccg ccatatgcgg catcaacatg
    63541 taaatagaaa tagatccctt catcttttaa cctttctctt aattggacga ttttatctac
    63601 actgtctact tgaccttctt ctgtcgttcc tacgacagca accacaccta gaattgggat
    63661 tttttgtcca gctaattcac gaattgtttt ttccaaagca ttaatatcca ttcgataatc
    63721 ctcttgaact gggatagcaa ccatctgatc taagccgact ccgcaaatat ctaacgcctt
    63781 catccaagaa tagtgttttg tttgagggac cagccatttc cctaatcttt ggatattttt
    63841 tccgctacgg gaagaagctg ctttgacctc atccatttct tcgtccgtaa agctttcggt
    63901 catttccaaa atttcttcaa cagataaatt caaaagttcc cactcagaca tttttttcac
    63961 tttttcaggc agcacttcct tgacagctaa aggaatcgat ttgatgcaac gggcgtacca
    64021 taatccttca agattagcaa tagaaccatc tgctgcaatg tgtccccatc cgtctgtcat
    64081 attgaataat gaagcaaaat cctgtcctac ttctgcttcc atttgcgaag ttgccataga
    64141 agattccaat gcaacattat ttgggttcca cagcatcgca tagttgtaag ctaataaagc
    64201 aggcatcaat gtttcagcat tcatttgtcc ccagtaacgg cctgctgaat gccatgggat
    64261 cgatcctgcg cgtaatcgct gactgacttc atccaagacc tctatcatat ggtcgcgggt
    64321 ggctagataa tctggagtga gcttatctcc ttcgctaatt gcaggcatat ctgaaggaat
    64381 ataattttct ctccatccaa gatgttcatc taccatcttg ttcaacaaca ttttataaac
    64441 tggtccattt tcagctttgt cgcctataaa gacggccttg atatccatat ctttcatttt
    64501 tcttccctcc atattttgtt ggtcaatgtc ttgcagatac atgtgtttat ctgtaacacc
    64561 tcttcactat agcgccaaaa atgagaattt tttttttata acatcaaatc cacgtagatt
    64621 tttacaaaca aaaataaata aagtcggatt tttctgataa ttcaacgcaa aaaagcgaac
    64681 aatttttcaa taaatcagtc ttctaaaata gataacctaa aaaaagcgaa caaacaaata
    64741 aaatgactgt ccttcattca ctaaacatat ttttattttt ttatattgtt aaaaattcgc
    64801 aatttatttt ttaatagaat tatctgtttt ccaaatttta taacataaaa aacctttttt
    64861 aacggcattt atatgctttt tcagaaatta actgatgatt tcaaaaagaa aacatgtcat
    64921 aatatttccc atattgtgca aaaaaataca ag
//
LOCUS       DAZUJR010000004        61702 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.004, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000004 DAZUJR010000000
VERSION     DAZUJR010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 61702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61702
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.004"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(122..499)
                     /locus_tag="ACG804_000227"
     CDS             complement(122..499)
                     /locus_tag="ACG804_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831191.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            755..1483
                     /gene="purC"
                     /locus_tag="ACG804_000228"
     CDS             755..1483
                     /gene="purC"
                     /locus_tag="ACG804_000228"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HFS4831192.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            1483..1737
                     /gene="purS"
                     /locus_tag="ACG804_000229"
     CDS             1483..1737
                     /gene="purS"
                     /locus_tag="ACG804_000229"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HFS4831193.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            1739..2410
                     /gene="purQ"
                     /locus_tag="ACG804_000230"
     CDS             1739..2410
                     /gene="purQ"
                     /locus_tag="ACG804_000230"
                     /EC_number="3.5.1.2"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HFS4831194.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            2411..4633
                     /gene="purL"
                     /locus_tag="ACG804_000231"
     CDS             2411..4633
                     /gene="purL"
                     /locus_tag="ACG804_000231"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HFS4831195.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            4618..6057
                     /gene="purF"
                     /locus_tag="ACG804_000232"
     CDS             4618..6057
                     /gene="purF"
                     /locus_tag="ACG804_000232"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HFS4831196.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            6080..7132
                     /gene="purM"
                     /locus_tag="ACG804_000233"
     CDS             6080..7132
                     /gene="purM"
                     /locus_tag="ACG804_000233"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HFS4831197.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVQESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            7129..7707
                     /gene="purN"
                     /locus_tag="ACG804_000234"
     CDS             7129..7707
                     /gene="purN"
                     /locus_tag="ACG804_000234"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HFS4831198.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            7704..9239
                     /gene="purH"
                     /locus_tag="ACG804_000235"
     CDS             7704..9239
                     /gene="purH"
                     /locus_tag="ACG804_000235"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HFS4831199.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            9255..10529
                     /gene="purD"
                     /locus_tag="ACG804_000236"
     CDS             9255..10529
                     /gene="purD"
                     /locus_tag="ACG804_000236"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HFS4831200.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            10651..11565
                     /locus_tag="ACG804_000237"
     CDS             10651..11565
                     /locus_tag="ACG804_000237"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HFS4831201.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(11698..13263)
                     /locus_tag="ACG804_000238"
     CDS             complement(11698..13263)
                     /locus_tag="ACG804_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4831202.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(13256..14707)
                     /locus_tag="ACG804_000239"
     CDS             complement(13256..14707)
                     /locus_tag="ACG804_000239"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFS4831203.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(14721..15737)
                     /locus_tag="ACG804_000240"
     CDS             complement(14721..15737)
                     /locus_tag="ACG804_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFS4831204.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            15957..17045
                     /gene="chvE"
                     /locus_tag="ACG804_000241"
     CDS             15957..17045
                     /gene="chvE"
                     /locus_tag="ACG804_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     substrate-binding protein"
                     /protein_id="HFS4831205.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            17099..18625
                     /gene="mmsA"
                     /locus_tag="ACG804_000242"
     CDS             17099..18625
                     /gene="mmsA"
                     /locus_tag="ACG804_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     ATP-binding protein"
                     /protein_id="HFS4831206.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            18627..19832
                     /gene="mmsB"
                     /locus_tag="ACG804_000243"
     CDS             18627..19832
                     /gene="mmsB"
                     /locus_tag="ACG804_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     permease"
                     /protein_id="HFS4831207.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            20089..21066
                     /gene="guaC"
                     /locus_tag="ACG804_000244"
     CDS             20089..21066
                     /gene="guaC"
                     /locus_tag="ACG804_000244"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HFS4831208.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            21330..22754
                     /locus_tag="ACG804_000245"
     CDS             21330..22754
                     /locus_tag="ACG804_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFS4831209.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            complement(22796..23053)
                     /locus_tag="ACG804_000246"
     CDS             complement(22796..23053)
                     /locus_tag="ACG804_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831210.1"
                     /translation="MPIRILTALVNKITIRKAFYISSAFFLFSNQTYNHLFLFKNVGV
                     IQFCCKHLFYLHIVNGRTNNGFFLVSLYRILFPKKKKQLEI"
     gene            23215..24324
                     /gene="pdhA"
                     /locus_tag="ACG804_000247"
     CDS             23215..24324
                     /gene="pdhA"
                     /locus_tag="ACG804_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0004739 - pyruvate dehydrogenase
                     (acetyl-transferring) activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HFS4831211.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            24327..25304
                     /locus_tag="ACG804_000248"
     CDS             24327..25304
                     /locus_tag="ACG804_000248"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HFS4831212.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            25329..26972
                     /locus_tag="ACG804_000249"
     CDS             25329..26972
                     /locus_tag="ACG804_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HFS4831213.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            26980..28386
                     /gene="lpdA"
                     /locus_tag="ACG804_000250"
     CDS             26980..28386
                     /gene="lpdA"
                     /locus_tag="ACG804_000250"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HFS4831214.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            28548..28823
                     /locus_tag="ACG804_000251"
     CDS             28548..28823
                     /locus_tag="ACG804_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HFS4831215.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            28829..29596
                     /locus_tag="ACG804_000252"
     CDS             28829..29596
                     /locus_tag="ACG804_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HFS4831216.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            29764..31593
                     /gene="typA"
                     /locus_tag="ACG804_000253"
     CDS             29764..31593
                     /gene="typA"
                     /locus_tag="ACG804_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HFS4831217.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            31854..33626
                     /gene="recQ"
                     /locus_tag="ACG804_000254"
     CDS             31854..33626
                     /gene="recQ"
                     /locus_tag="ACG804_000254"
                     /EC_number="5.6.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HFS4831218.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            33740..34042
                     /locus_tag="ACG804_000255"
     CDS             33740..34042
                     /locus_tag="ACG804_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HFS4831219.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            34045..35208
                     /locus_tag="ACG804_000256"
     CDS             34045..35208
                     /locus_tag="ACG804_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFS4831220.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            35234..38662
                     /locus_tag="ACG804_000257"
     CDS             35234..38662
                     /locus_tag="ACG804_000257"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004736 - pyruvate carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009374 - biotin binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HFS4831221.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            38683..39807
                     /locus_tag="ACG804_000258"
     CDS             38683..39807
                     /locus_tag="ACG804_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP-associated domain-containing protein"
                     /protein_id="HFS4831222.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            39788..40234
                     /locus_tag="ACG804_000259"
     CDS             39788..40234
                     /locus_tag="ACG804_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFS4831223.1"
                     /translation="MIAVIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESA
                     KVCQLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQ
                     LQSLLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            40218..40556
                     /locus_tag="ACG804_000260"
     CDS             40218..40556
                     /locus_tag="ACG804_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HFS4831224.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            40675..41235
                     /gene="rsmD"
                     /locus_tag="ACG804_000261"
     CDS             40675..41235
                     /gene="rsmD"
                     /locus_tag="ACG804_000261"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HFS4831225.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            41232..41723
                     /gene="coaD"
                     /locus_tag="ACG804_000262"
     CDS             41232..41723
                     /gene="coaD"
                     /locus_tag="ACG804_000262"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HFS4831226.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            41713..42756
                     /locus_tag="ACG804_000263"
     CDS             41713..42756
                     /locus_tag="ACG804_000263"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HFS4831227.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            42915..43643
                     /locus_tag="ACG804_000264"
     CDS             42915..43643
                     /locus_tag="ACG804_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HFS4831228.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            43759..44004
                     /locus_tag="ACG804_000265"
     CDS             43759..44004
                     /locus_tag="ACG804_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFS4831229.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            44001..44219
                     /locus_tag="ACG804_000266"
     CDS             44001..44219
                     /locus_tag="ACG804_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HFS4831230.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            44355..44894
                     /locus_tag="ACG804_000267"
     CDS             44355..44894
                     /locus_tag="ACG804_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HFS4831231.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            44887..47160
                     /locus_tag="ACG804_000268"
     CDS             44887..47160
                     /locus_tag="ACG804_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HFS4831232.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            47198..48244
                     /gene="holA"
                     /locus_tag="ACG804_000269"
     CDS             47198..48244
                     /gene="holA"
                     /locus_tag="ACG804_000269"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HFS4831233.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(48333..48587)
                     /gene="rpsT"
                     /locus_tag="ACG804_000270"
     CDS             complement(48333..48587)
                     /gene="rpsT"
                     /locus_tag="ACG804_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HFS4831234.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(48987..49256)
                     /locus_tag="ACG804_000271"
     CDS             complement(48987..49256)
                     /locus_tag="ACG804_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831235.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(49518..49646)
                     /locus_tag="ACG804_000272"
     CDS             complement(49518..49646)
                     /locus_tag="ACG804_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831236.1"
                     /translation="MFEKLKYFIGTIGWFLLAVLLILGLAYLLFPDLIQNVFDTAF"
     gene            complement(49726..50181)
                     /locus_tag="ACG804_000273"
     CDS             complement(49726..50181)
                     /locus_tag="ACG804_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HFS4831237.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(50319..52247)
                     /locus_tag="ACG804_000274"
     CDS             complement(50319..52247)
                     /locus_tag="ACG804_000274"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFS4831238.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(52444..53277)
                     /locus_tag="ACG804_000275"
     CDS             complement(52444..53277)
                     /locus_tag="ACG804_000275"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HFS4831239.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(53469..54173)
                     /locus_tag="ACG804_000276"
     CDS             complement(53469..54173)
                     /locus_tag="ACG804_000276"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFS4831240.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(54196..54822)
                     /locus_tag="ACG804_000277"
     CDS             complement(54196..54822)
                     /locus_tag="ACG804_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFS4831241.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            55148..57523
                     /locus_tag="ACG804_000278"
     CDS             55148..57523
                     /locus_tag="ACG804_000278"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HFS4831242.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(57547..58038)
                     /locus_tag="ACG804_000279"
     CDS             complement(57547..58038)
                     /locus_tag="ACG804_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HFS4831243.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            58225..59145
                     /locus_tag="ACG804_000280"
     CDS             58225..59145
                     /locus_tag="ACG804_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFS4831244.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            59299..59643
                     /locus_tag="ACG804_000281"
     CDS             59299..59643
                     /locus_tag="ACG804_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HFS4831245.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(59833..60333)
                     /locus_tag="ACG804_000282"
     CDS             complement(59833..60333)
                     /locus_tag="ACG804_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4831246.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            60861..60944
                     /locus_tag="ACG804_000283"
     tRNA            60861..60944
                     /locus_tag="ACG804_000283"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:60895..60897,aa:Leu,seq:cag)
     gene            complement(61268..>61702)
                     /locus_tag="ACG804_000284"
     CDS             complement(61268..>61702)
                     /locus_tag="ACG804_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HFS4831247.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT        20233 a        10662 c        13216 g        17591 t
ORIGIN      
        1 gcagatccgt tagcggttct gcttctttta gtttattata ttttcttatc aataatagga
       61 acctgatttt aaaagcggct acctctttac cgtgcctctt tacatacaaa aaatagagga
      121 attaagcgta aatggcttgg ctattataac taaaatgctg gttatggaga tgttgcagca
      181 agttttcgag aaaagcgtat tccatctctt gtccattgaa taagatctgg atacgataat
      241 gatttttgaa acgcttctgt tcatgaatct gactgattga aagttcgcct ttgtgttctg
      301 tctgataaag aaaagtcctt ttacggcatt cagcacagcg cttggttgct cggcggattt
      361 ttcggaatgt ataaaaacta gtatctttat tgcataaata aacgtctttg atcgacagca
      421 aatcattata tagacaggaa cgttcttcag ctgttaattc tgataaaaaa agctgacctt
      481 gttttattgc atcttccatc ggcaagtgcc tcctcgaacc cattatccaa atttttagtt
      541 aattctaata taccatcatt aagtataaat gtaaacgctt gttgatggta taagattttc
      601 gtttctgata aaacacgaac attaaaagaa tctaatgcct taaatgtaca tatttttgtt
      661 gatttataaa aagatgattg ctaaaattta aagtgaaaaa acgaacaaaa aacgatgtat
      721 ttgcttttaa tgtaaataaa aaggagagac gtacatggag aagaaagaac ttttgtatga
      781 aggaaaagcc aaaaaaatat atcttacttc tgatgagaac ttgatttgga tagaatattt
      841 agatcaagca actgcgttga atggcgcgag gaaagaccag ataagtggaa aaggagaatt
      901 gaataatcaa atcacaagtg caattttccg ttatctgact caaagaggaa taaaaaatca
      961 ttttattgaa caattgtcta aaaccgaaca attagcaaaa aaagtacaaa ttatccctct
     1021 ggaagtggtt atccgaaata ttgcagcagg aagtttctca aaacgtctag gtgttcccga
     1081 aggtaaagaa ttcatcaaac caatcattga attctactat aaggatgacc agttggatga
     1141 tccatttatc aatgaagagc atatctattt cttacaactt gcaaagccgg aagaaatcag
     1201 tgagctgaaa gcccaagcgt tggctattaa tgaaattttg accgaattat ttgctaaggt
     1261 cggtttggtt ttagtagatt tcaagctaga atttggccgg tcgaatggac aaattttgct
     1321 tgcggatgaa gtaacaccgg atacttgccg attatgggat gaacgtacga atgaacatat
     1381 ggacaaagac gtttaccgca gagatctagg tgatttgatc ccagtctatc aagaagtata
     1441 taaccgtcta tcggaactaa ctgaagaaaa ggagcgagta tgatgtattt cgtaaaagta
     1501 tatgtaacct ataaagattc agtgttagat cctcaagggg aggcagtaaa aaaagcagtc
     1561 catcgtatgg gatatgaaac aatcgaagat atccgaatag gaaaatactt tgagatacaa
     1621 cttgctgatg cagaagaacc aatcgataca gtgattgaaa cgatttgtga caagctgctt
     1681 gcaaatgtaa atatggaaac ataccgatat gaaatcaaaa aaatggagga agtataacat
     1741 gaaatttgcg gtcatcgttt ttccaggttc aaattgtgac gcagatatgt tatgggcagt
     1801 tcgcgagatc atgggcgctg atgccgaatt tgtacggcat gatgagtcct ctttagaagg
     1861 atttgatggg gttttactgc cgggaggatt ctcctatggt gactatttga gatgcggtgc
     1921 gattgctcgg ttttctacaa tcatggaaga agtgattcgt tttgctgaag aagggaaacc
     1981 agtattcggt acatgcaatg gattccagat attgacagaa gcaggacttt tgccaggtgt
     2041 actgagacga aatgagtctt tgcattttat ttgcaaaact gtaccattga aagtcaaccc
     2101 caagacggcc tttacttcag agtatgaagc cgacgaaata atctatcttc cagttgctca
     2161 tggggaagga aattatttct gtgacgaaga aacacttcaa gaactaaaaa aaaataatca
     2221 gattgccttt acttataatg acaacatcaa cggcagcgtg gaaaacattg cagggattac
     2281 gaacaaagca gggaatgtgt taggaatgat gcctcatcca gaacgtgcag tagaagactt
     2341 gctaggatca gaagatggga aacggttctt tgcttccatt ttaaaaaact tcggaaaggt
     2401 gaccgtatag atgaaaacat tgaaagaacc gacagctgaa gagatcaaga aaaaaagaat
     2461 ctatgccgaa tggggattga ctgatgaaga atatcgaatg atcgaagaag atatcttagg
     2521 aagaatgcct aattatacgg aaactggact gttttctgtt atgtggagcg aacattgttc
     2581 ctataaaaat tctaaaccgg ttctacgcaa atttcctact agtggacctc atgtgttgca
     2641 aggccctgga gaaggcgcag gcatcgtcga catcggtgat ggactagcag ttgtcttcaa
     2701 agcagaaagt cacaatcatc cttcagccgt ggagccttat gaaggagctg cgacaggagt
     2761 tggcggaatc atcagagata ttttcagcat gggggctcgt ccaattgcgt tgctagattc
     2821 attgaggttc ggcgaattag ataatccaag aacgaaatat ttactagaag aagtagttgc
     2881 aggtatcggc ggatacggca attgtatcgg cataccgact gtaggcggcg aaattgcatt
     2941 tgatccttgt tatgaaggaa acccattagt caatgcaatg tgcgtaggtt tgattgaaca
     3001 caaacatatc cagaaagggc aagccgctgg cgtcggtaat tcgatcatgt atgtaggtgc
     3061 aaaaacaggt cgcgacggta tccacggagc aacttttgcc tcagaagaat ttaatcaaga
     3121 agaagaacag caacgttctg ctgtacaagt aggcgatcct tttatggaaa agctgctgct
     3181 tgaagcgtgt ttggaattaa tcttgcatca ttcggattct ctaataggta tacaggatat
     3241 gggagcagca ggacttgttt catctagtgc ggaaatggct tcaaaagctg gctcaggact
     3301 tatattgaca ttagatgaag tcccacaaag agaaactggg atgacacctt atgaaatgat
     3361 gttatcggaa tcacaagaac ggatgttgat ttgtgttaaa tcaggagagg aagaaaaaat
     3421 ccaagaacta tttcagaagt atgatctaga tgcagtcact atcggtaaag taacagacga
     3481 cgggcaatat cggctatatc atcaaggaga agaagtagca aatctgccag tcgatgcatt
     3541 agctgaagat gcaccagttt atcataaaga aatgaaagaa ccagctcgaa tcgtagaatt
     3601 tcagcagtta gctccttatc agccagttat cgaagaacct ggacaagtat tgcttgatct
     3661 gctgcagcaa ccgacgattg cttcaaaacg ttcaatctac gaaacttatg attcacaagt
     3721 acaaaccaat acagttgtcc gtccaggaag cgatgctgct gtgatgaggg ttagagggac
     3781 gaataaagcg ttagctatga ccacagactg caacgcgcgc tatctgtatt tggatccaaa
     3841 aatcggagga caaatagcag tggcagaagc tgctagaaat attattgcta gcggtggtaa
     3901 gcccttggcg atcaccgact gcctgaacta tggttctcct gataaaccag aagttttttg
     3961 ggaattatcg acttcagctg acggaattgc tgctgcgtgt gaaacgttag gaactcctgt
     4021 tatttcagga aatgtctctt tatataatga aacggatggt caagcaatct atccaacacc
     4081 aatgattggt atggtcggat tgattgagga tcataaacat atcactactc aggaattcaa
     4141 aaaatcaggg gatctaatct atatattagg taagacgttt gcagattttg atggcagtga
     4201 attacaaaag atgcagcttg gaagaatcga aggtgtgatc cgaaactttg atctatccat
     4261 tgaaaagaga aaccaagagt tagtattgac agccatccaa aacggattga ttgaaagtgc
     4321 tcatgactgt tcagaaggtg gcttggcaat tgcactggca gaatcagctt tcaaacatca
     4381 gctagggata tctgtacagt ttgaattgtc ctctgctcaa ttatttgcag aaactcaatc
     4441 aagatttgtg ttgacagtcg caccggaaaa taagacacga ttcgaagaaa tgatgggaga
     4501 tgctgctgtt ttagcaggta aggtgacgga tgaagcgata atcgaaattt cagcaactga
     4561 cggtcagatc aaaatagaaa ctgcagtagc aagaaagtgc tgggaggatg caatcgtatg
     4621 tcttatgaag tgaagagttt aaatgaagaa tgcgggatct tcggtgtttg gggtcatcca
     4681 gacgccgcta gtgtggcata cttcgggctc catagtcttc agcatcgagg acaagaaggt
     4741 gcaggtatcg tgtccaatga tcgaggaaag cttaaggggc atcgagattt ggggctgctt
     4801 tctgaggtat tcaaagatca aagaaaattg cagcagttaa caggagaagc tgcaatcgga
     4861 catgtacgtt atgcaacagc aggcaatgga agtgtggaca atattcagcc ttttctattc
     4921 aaatttcatg atcagtcgat cggcttagcg cataatggta acttgatcaa tgctcgttcc
     4981 cttagaaaag agttagagga aaatggggcg atcttccatt ctaactccga tacggagata
     5041 ttgatgcatt tgatccgacg aagtgaagaa acagattttt taaataaatt aaaaagtgct
     5101 ttgaatgaag tcaaaggtgg ctttgcctat ttattaatga cagaaacggc aatgattgcc
     5161 gctttggacc caaatggttt tcgtccatta gcaatcggac aaatgaaaaa cggagcatac
     5221 gtgattgcct cggaaacttg tgcattagaa gttattgggg cacgttttat aagagatgtc
     5281 cagcctggtg agatagtgat catcaatgac gaaggaatcc agattgattg ctttacgaag
     5341 gacacgcagc tttctatttg ttcgatggaa tatatctatt ttgccagacc agattcaaac
     5401 atcgcaggga tcaatgtgca tactgcacgg aaaaatatgg gacggaattt agcgaaagaa
     5461 tcgccagtaa aagcagatat ggtcgttggc gtacctaatt cttctttgtc agccgcaagc
     5521 ggttatgcgg aagctagtgg aatcccttat gaaatcggat tagtaaaaaa tcaatacatt
     5581 gcccgaacat ttatccagcc aacgcctgag ctaagagagc aaggtgttcg aatgaaatta
     5641 tctgctgtac gaggagtagt ggaaggtaaa aaggtgatta tggtcgatga ttcaattgtt
     5701 cggggtacga caagcagacg gatcgtccat cttttgaaag aagcaggggc aaaagaagtc
     5761 catgtgagga ttgcttctcc tcctttgaaa tatccatgtt tttacgggat tgatattcaa
     5821 acgcgtaaag aactcattgc ggcaaatcac acgattgatg aaatcaaaga atgtatcggt
     5881 gcagattctt taggtttttt aagtgaagag ggtctgatcg aatcgatcgg tctggaaaaa
     5941 gatgctccgt attcaggatt gtgtatggct tatttcaacg gagattatcc gacgccgtta
     6001 tatgactatg aagaaaaata tcaggaatca ctaaaagaaa aagtatcgtt cttttaaaag
     6061 cagaccaaga agggagtata tgaattcaat ggcaaatgca tacgcaaaag ctggcgtaga
     6121 tgtcgaagct ggatatgaag tagtagaacg gatcaagaag catgtcaaaa aaacggaacg
     6181 tttaggtatg atgggcgcta taggaggatt cggcggttgt tttgatttat cggtctttca
     6241 attaaaagag ccagtccttg tctcggggac cgatggcgtg gggacgaaat tagcagtggc
     6301 aatcgaagca gacaaacacg atacaatcgg gatcgactgc gtagcgatgt gtgtcaatga
     6361 tatcttagca caaggcgcag agccgttata tttcttagac tacttagcaa cggggaaaaa
     6421 tgatccgtta cgtttggaaa atgtagtaaa aggtgtagca gatggatgtg ttcaaggaaa
     6481 tatggcgctg attggcggag aaacagctga aatgcctggt atgtactcag gtaatgatta
     6541 tgatctagcc ggatttgctg tagggatagc tgaaaaatct caattattga caggagaaac
     6601 gatcaaccca ggagatgtgt tgcttggaat agcatctagc gggattcatt caaatgggta
     6661 ctctcttgtt cgcaaaattt tctttgagca gcagcagttt tctttatcat caaaactgcc
     6721 agaattgaaa aaaacacttg gcgaagaatt gcttgagcca acgaaaatct atgtttcttc
     6781 cttgcttccg ctgatcaaag aaaagaaaat aaaaggagct gcacatatca ctggtggagg
     6841 gtttgtagaa aatatcccgc gaatgttacc agaatctatg gctgcacaaa tcaaacttgg
     6901 ctcatggccg attcttccaa tattcggctg tttacaaaaa tatggtgaaa ttcctgagat
     6961 ggagatgtat gaaatcttca atatgggcat cggtatggtc ctggcagtcc aagaatcgaa
     7021 agtaaaagaa atagtacacg aaattgagca agctggcgaa aaagtttatg aaatcgggaa
     7081 agtgatcgcc aaagaaaaac atcgtgtggt gtttatagga gaagaacgat gagaatcgct
     7141 gtttttgctt ctggaaacgg aagcaacttt caagcgctag ccgattatct atcgaaaaaa
     7201 ggattggaat cttcgattga ctggttgttt tgtgatcagc ctgaagcata tgttttgaaa
     7261 cgtgcaactg cgttgagtgt accggcagat tgtttttcac ctaaagaatt tgattcaaaa
     7321 aaagagtatg aagaagcaat tttgcataaa ttgaaagaaa aaaagatcga tttgatcgta
     7381 ttagctggat atatgcgaat cattggaccg gtattgctga aaaattatga taaaagaatc
     7441 atcaatatcc atccgtctct tttacctgcc ttccctggtt tgcatggcat acgtgatgcc
     7501 tttgaagctg gagtaaaaga aacgggtgtc acaattcatt atatcgacca aggtgtagat
     7561 actggaccaa tcatccggca ggaaaaagtg agaattgaac aggaggacac gttcgattct
     7621 ttagaagaaa aaatccatag agtagagcat cgaatctatc cagaagtgat tagtgaaatt
     7681 attgaaaatg gaggctatct gaaatgacaa gagcattgat cagtgtatca gataaaactg
     7741 ggattgtagc attcgcccaa ggtttgattg aacaaggagt agaaatcatt tcaacaggag
     7801 gaacaaagca tgcgttggat aaagctggga tcaaaacgct ttcgatcgaa gaagtgacag
     7861 ggtttcctga aatgatggat ggccgtgtca aaacacttca tcctaaaatc catggtggtc
     7921 ttttaggaag acgcgatctc cctagccata tggaggcaat ggaaacggaa aatatccaac
     7981 caatcgactt tgtttgtgtc aatttatatc ctttcaaaga aacgattatg aaaccagatg
     8041 tcgaaatagc agaagctatt gaaaacattg atatcggtgg tcctagtatg ctccgtagtg
     8101 cagcaaaaaa ccatgaattt gtcacctctg ttgttgatcc atctgactat gaagaagtac
     8161 tttcagaatt acgtcagtat gggcatactt cactttcttt cagacaaaaa ctagcggcaa
     8221 aagtctttcg tcatactgcg gcatatgatg cactgatcgc tcaatactta acggattggg
     8281 tggaagaaaa agaaccggaa aaattgacac ttacgtatga acgaaaacaa acgcttcgtt
     8341 acggtgaaaa tagccatcaa gccgctgcct tttatcagtc cgctcttctg gaaaaatatt
     8401 cgatcgcagc agcaaaacaa ctccatggga aagaactttc ttataataat atccgagatg
     8461 cagatgctgc gctacggatc atgaaggaat atgacgagcc aacggtagtc gccttgaaac
     8521 acatgaatcc ttgtggtatt gggacagcat ctacgatttt agaagcgtgg gaagcagcgt
     8581 atgaagcaga tcctgtttca atctttggtg ggatcatcgt tttgaatcga gaagtagatc
     8641 tgccaacagc agaacagatg cataagctgt ttctagaaat catcattgcc ccttcttata
     8701 cacaagaagc tttggaatta ctgcaaaaaa agaaaaacat ccgattactg acagtagact
     8761 ttgcgcagga agaaaatcaa aatcgagaag aaacggtctc agtcttaggt ggacttcttg
     8821 tacaagatca agatctggca atagaaaatg aagaagagtg gaaagtcgtg acaaaacgta
     8881 agccgactcc agcagaagca aaagcattag cgtttgcttg gagagctgtc aaacatgtga
     8941 aatctaatgc gatcgtactg gcaaacgaac gtcagacagt aggaatcgga gccgggcaga
     9001 tgaatcgagt cggttcagta aaaattgcga ttgaacaagc gcaagagaaa atggaaggtg
     9061 cagttttagc tagcgatgct tattttccaa tggatgattc ggttgaatat gcagccaaac
     9121 atggtataaa agcaatcatt cagccaggag gaagcatcaa agaccaagat tctattgata
     9181 tggcgaataa atacgatcta gcaatggtct ttactgatgt tcggcatttt agacattaga
     9241 gaggagtcgg ataaatgaac attttggtga tcggtgcagg tggtcgtgaa catgcaataa
     9301 gtaaaaaact tttagccagt ccgaaggtgg atacggtgta ttgtgcgcca ggaaatccgg
     9361 ggatgacaaa agatggtatc aattgtgtcg ctatcagtga gcgagatcat tcagcgttaa
     9421 tccattttgt taagaaagag gctattgatt ggagtatcgt tggtcctgaa gttcctttgt
     9481 taaatgggat cgtcgatgat tttatggcgg aaggattgaa aatcttcggt ccgacaaaag
     9541 cagcagctct gatcgaaggt tcgaaaagtt ttgctaaaca attaatggat acttatcaaa
     9601 tcccgacagc taaatccaga agttttgaat gttacgaaaa agcagcagcg tatatcaaag
     9661 aaaatggtgc gccaatcgta gtgaaagcgg acggcttagc agctgggaaa ggtgtagtcg
     9721 tggctaccac agtgaaggaa gcgctggatg cggcagaaca aatgttgaac cagcatcgat
     9781 ttggggatag tagcaaaaaa atcgtcgtag aagagttttt ggcaggagaa gaattctccc
     9841 ttttggcgtt tgtccgtaat accaaggtgt atccgatggt catttcgcaa gatcataagc
     9901 gggcatttga taacgataaa gggccaaata caggcggaat gggtgcttat tcaccagtac
     9961 cgcaaatttc aaaaaagatg attgaaaaag ctgtggaaga agttttaaaa ccagcggctt
    10021 tgggaatgaa agaactagga cgctctttca cgggtgtttt atatgcgggt ttgattgcta
    10081 cgaaggaagg accaaaagtg atcgaattca atgcgcgttt cggtgatcct gaaacgcaag
    10141 tcgttctttc tcggttgaag agtgactttg cgcaagtaat cgatgattta ttagagaatc
    10201 gtacagtaga gttaaagtgg cagcaagaag gatacaatgt aggcgttgtg gttgcagctg
    10261 ccggttaccc cgaagaatat gagacaggaa tggttctacc agattttctg gaagaagagc
    10321 tttctgttta ctatgctgga gtttcctcaa ataacggcaa actagttgga gcaggaggac
    10381 gtctttattt agtagaagca tacggtgaga cgatcaaaga agcacagaaa aaaatttaca
    10441 ccgcgttaat ggataaaacg acagatggaa cattttatcg tacagatatt ggagaaaaag
    10501 ctgccaatag cgaactgatc gtgaagtaaa tcagctgctt ccatttataa aaaatacaac
    10561 aaacataatc ggaagcgccg attttagtga agccttttca taaagagtgt ggtacacttt
    10621 tgttgtgtat ataaataagg aggagttcag atgaaaaaaa ttcaattagg tacttctgat
    10681 cagaaagcag ctgcagtgat cttaggctgt atgcgtatca acaatgcgga agatccagta
    10741 aaagtgattg agacagctta tgaaaacggc attgattttt ttgaccatgc agatatttat
    10801 ggaaacggtg aatgtgaaga aatctttgca gatgctctag caaaaacatc aatcaaacga
    10861 gaagatcttt ttattcaaac aaaatgtgga atcgttccag gtgtgatgtt tgatttttct
    10921 aaaaaacata tcattgaatc tgtagaaaaa agtttgaccc gtctgaaaat ggattatgtg
    10981 gatgctttac ttcttcatcg tccagataca ttggtagaac cagaggaagt agctgaagcg
    11041 tttgatgaat tggaacggtc aggaaaagtt cgttattttg gcgtcagcaa tcaaaaacca
    11101 atgcaaatcg aattgctgaa aaaatatgtt cgtcaaccat tagtagctaa tcagctgcaa
    11161 tttggcttga aacatactgg aatgatcgat caagggattc atgtcaatat gacagatgaa
    11221 gcaagtatcg atcatgacgg tagtgtactt gattattccc gattgcatga tatgacgatc
    11281 caagcatggt caccatacca gtatggattt tttgaaggtg tatttatcgg gaacgaaaaa
    11341 ttccctgaat taaaccaaac attagaagaa ctagcagcta aatatcaaac gacaccaact
    11401 ggcttggctt ctgcttggat tttacgccat ccagccaata tgcaagtgat cgccggtacg
    11461 atgaacgtag ggcgaatcaa ggaaatcgct caagcttcag aaattaatat gtctcgggaa
    11521 gattggtacg aattgtaccg tgctgctgga aacattttac cttaaagatt gtcataagca
    11581 ggtcaaaagg gctataaatt aaaaagacag aataacttga aagctgtttt cagcttcgag
    11641 atattctgtc tttttttatt gcaaatggaa agagtatcat tgtacggatt tcgtttatta
    11701 gttatttttg tttttaagga aaagctgtgt ccgatattct tttggagaaa tcccttgttt
    11761 tttcttaaat aaataactga aatagttagg gtcattataa ccaatttcaa aagcaatatc
    11821 tgaaatacga tagtctgatt gctgcaataa tttttttgct aattcgattc tttgttctgt
    11881 cagataatcg atgaatgttt ggttaaacga ttgagaaaaa atcgtactga aatgagaggg
    11941 acttaatgca acttgttgag cgacccaagt taaggacata tctggatcgg taaaattttc
    12001 tttgataaaa tccaatgcat ggttcaaaat tggctgatat ttgttccttg aaggctgtga
    12061 gggcagagca gttaagaaag aaatgaacat ataaactgtc gaacggtaaa gcgagtcgtc
    12121 ggcgctgatt gctaagcgtt gactggtgga tgtgcaatga accatttctt gcgggatttt
    12181 cttttctttc aggcagacat gctggagtag cttagtcaag acaaataaac gatataatcg
    12241 tgttcgagtt ggtgtgcctt gtggtttcgt caagtgttcg atgtacttag atacttcgtt
    12301 tttcgataat gaagacaaat caagtgagag gtcaaagtaa aagacagaat caactggaag
    12361 tttcgcttct tgaatcaaat cctcatagct gataatttgt tctttaaggg aactggcggt
    12421 ttcaagtatc atctgcgtga tctcaaaaga tgcaggtaat tcgctgattc tttctgcgac
    12481 aggaccaatg gcgacagaaa aattattttt ttgtcccttt tctaattcat ggaccaacgt
    12541 ttgggctacc tgataactgg tctcgatcac attttcttca agagaatcaa ctattaaaaa
    12601 tttgatgaat cgagaggaaa cagcagagaa gatcacttgt tgattctccc taaataaaaa
    12661 cttcaaataa tcactgagat gagcgtaatc ttcaaagtct gtactgactt ggtttgctgc
    12721 taataatacg gtcatttttt tccctgctaa agagcgattg aaagattcag caagtttcaa
    12781 tgtttcactg atcgtaagtg agcctttgaa caaaccgttc aagaaatgat tttttttcaa
    12841 ttcgaaaaca agatcagaag aagtgtgcgt ttctttttgc tgcaaatcta aagcagttac
    12901 tgctttttct attgcttgtt tcaattcgct acttttaatc ggtttaagca gataatcatc
    12961 tgcctgtacc tggattgctc ctttcatata atcgaaatcg tcgaatccac taataaatat
    13021 gagacgagtc caaggaagta gtttccttgc ttcttttgaa aaagtcaacc cgtccatgaa
    13081 aggcatttgg atatcagtca gaatgatgtc gggctgtaag tcgataattg aagacagtgc
    13141 catctcacca tctccagctt cgccgacata agtgattgga taataagaac caaggacagt
    13201 tatttgttcc cgcaagttat tgcgaatgag gtattcgtct tcgatgataa aaactttata
    13261 catgtttgtt tcctccaatt gttttgggag atagagggat catcagtgtg acagttgttc
    13321 cttctcggta tttgctgtca atcgtgatag gtttttgatc atttccgtaa taaagaagga
    13381 gacgcttgtt tacgttgtaa agtccgtagc cgatactgaa atctgaatcg atccctttgg
    13441 ctaactcttt acgtatttct gccagttttt ctgcagggat gccaatcccg ttgtctataa
    13501 ctttgaattg gatcatctca tcaattttgc atgtggtaat acgaataaat cctttgtgac
    13561 ggacgtactt cgttccatgg tatacagcat tttcaatcaa tggctgcaag atcattttta
    13621 aaatagaaac aggaaaaagt gtttctggta tatcgatctt atagtcaagc atatggccgt
    13681 atcttatttt taagatgact agataatcat tgatatggct aatttctttt tcaagaggaa
    13741 tccagtcttg tcctttgctt aaagacgtac gaaaaaagcc ggaaagtgca tgggtcatag
    13801 tcagagcttc ttcaaagcag tcttgttcga tcaaagaaat aatggcatcc aaactgttat
    13861 aaataaaatg gggagtaatc tgagcttgca atacacgaac ttcactttgt gctaaatggt
    13921 attgtttcaa agcgttctcc cgtaaagact ggtttagatc ttccgccatt ttattcatgc
    13981 tagcggtaag tgtttgtaat tccagtgttt ccggcagggt taaacgaaag ccaaggttcc
    14041 ctgaagaaag ttgttctgac atctcgatca gctgattgat cggttcttgg acctttctct
    14101 ctaaaaagcg acgattcttt ttcgcataga aaaaaatggt actaagaact ccaagttcca
    14161 ctattgttaa tagaatgagc gagcggacaa gtgtcgtatt ttttttgctt gctaagtcga
    14221 tctccacacg aacaaaatct tgtaagatat ctgacagcag ttgagtgaca gaatctacct
    14281 gattgatgat ctcttcattg gtatccataa aatcttttgc caagatatta ttgatcagct
    14341 cgttttgata atcttccagt gtatcgatcg tacgtagcga tacatctaac gtactaattt
    14401 ctttaagtgt atttgtatta tttttgatct ctcgaatatc attcctaagt tcttctagga
    14461 tattttcctc attgaactca tctacggtta cttggccaga aatcaagtcc cacatacttt
    14521 ccaaaacttt ttgatcaacc ttcaaagcaa ttgcatctgc tttttggata tttgcgatcg
    14581 tctgttgata aatcaaaagc tgttgcgaat ataacagtat gctcagtagc aaagggataa
    14641 cagcaaatag aagcatggct ttgtttgctt gggcaaaaat ctgttttatg cttaaatttt
    14701 ttgtcatgat acttctccag tcaataattt ctggttggga tgttagctat attctgctgg
    14761 gaaaagacag tctcggaaat aaaaatatct ttaggtaatg tttttcctgt ttgaatattt
    14821 ccaaaataac gagtaacggt attggctaca taccagccga catcaggttt acactcgact
    14881 acacaattga cgattcctga gcgtagcttc tcgatcatat cttcttgtcc atcaatagtt
    14941 acaatgatca aatcttctcc aggtttgatt gatgtttctt ttatcgcagc taaagcaccg
    15001 tgagtcattt catcactatg gctgtataat acatcgattt cggataaatc atttgtttct
    15061 aaatatcgtt tcatctggtc ttttcctttc atccgaataa aatcaccgac aattcggtga
    15121 acaatagtca tcggaggttt atggtcgatg gttccatctt tttttagggt tggtttacga
    15181 ttgattgatt ccaaaaatcc ttcggagcgt agcttggtcg gtgtggagtt ctctgaacca
    15241 gcaagttcta ggattctgat ttcctgtttc tttgaatttg tgaagtgatt gctgacaaat
    15301 aaacccgccc gatttccttc tgctttgaaa ctggggccaa tgtgggtgac gaaaagctcg
    15361 ggatcattcg tttgaatatg tctgtcgaca agtatgacag ggatccctgc tcgctttgct
    15421 tcttttaata cagagtccca cccggattct tgcaaaggag taaaaatgat catatccact
    15481 ttataggcaa tgaacgtccg tatatcttgg atttgccgtt cctgattcat gtagccattt
    15541 cggtagagaa cttggtaatc ttctttttca agcgcagtga taattgattc agtatgcttt
    15601 ttccgccagc tactctccgt tcctgattgc gaaaaaccaa cgactagtgg gtcaggtgct
    15661 tcctttgtat taggtgtaca ccccatcatt tggtaagcga ttacaacaag ggctaaaaaa
    15721 aataaaacac gtttcacttt aaatcactcc atctggattt gttagtacta tcttatcaga
    15781 taaaagggaa aatcaaagtc aaaaggaatc aatcgaaaaa aatccaagaa acttaaaaaa
    15841 atccaagaca aaaaaagtac acctaaaaaa tttaaagtaa atcccataaa aaaatcaatg
    15901 ttaacgcttt ctttattagc tatactcggt gtatcaattg aaatggggga taaaaaatga
    15961 aaaacaaatt tagaaagatt gttgggacta tcgctatttt gaccgcaagc attctattaa
    16021 gtgcgtgtgg caattcagga tctgcagatg atagtacggg gtatgtagga atcgctatgc
    16081 cgaccaaatc agcagaaaga tggatcgctg atgggaacaa catggtctcg gaattagaaa
    16141 aactgggtta taaaacagat cttcaatatg gagaagataa agtagaaaat caagtagcac
    16201 aaatagaaaa tatgattaca aaaggggtag atacacttgt gattgcttct atcgatggtt
    16261 cggctttaac tgatgtgtta gctaaagcaa aagaagcaga tatcaaggtg atcgcctatg
    16321 atcgtttact gatgaattca gaaaatgtcg attattacgc gacttttgat aattttggag
    16381 taggtgtatc gcaagcagct tatattgaag agcacttagg attgaaagaa ggaaaaggac
    16441 cattcacgat tgaattattt ggtggctcgc ctgacgacaa caacgcacta atcaattaca
    16501 acggagtgat gtctgtttta caaccatata tggacaacgg tcagttggtc gtgccatctg
    16561 gacagacgag tttcagtcaa atcgctacgc ttcgctggga tggttctacg gcgcaagcaa
    16621 ggatggataa tctgttaagc gcaaattata ctgaccaaac attggatgct gttttgtcgc
    16681 catatgatcc aataagttta ggaatcattt cgtcattaaa aggcgtgggg tatgggagtg
    16741 aaagtaaacc tttacctgtg attactggac aagatgcgac agttgctggc gttaaatcga
    16801 tcattgccgg ggaacaaaca caaacgatct ttaaagacac acgtatctta gcaaaaaata
    16861 cgattgaaat gatcaaagca atcagtgatg gagaagaggt tccggtcaat gatactgaaa
    16921 cttatgataa tggggtgaaa actgtcccta cgtatttagc aaatacagta tctgtcgata
    16981 aagataatta tcaagcagag ctgatcgaca ccgattatta taaagaatcc gatctgaaaa
    17041 attaagagga accaaacaag gaactaaaga gatctaagtc agagagagga taagaattat
    17101 ggcggattgt attttaaaaa tggcagatat caccaaaaaa ttttctggaa tccgagcgtt
    17161 agattgcgtg aatctgatga ttgaacgtgg ggaaatccat gcattgtgcg gagaaaacgg
    17221 agcgggaaaa tcaacattga tgaatgtctt gagcggcttg tatccatatg gctcctatga
    17281 cggggaaatc ttttatgatg gaaagctgtg tcaatttaaa gatttgaaag atagtgaaga
    17341 aaaaggcatc gtcatcattc atcaagaatt agcactaagt ccttatcttt caataaaaga
    17401 gaatattttt ctcggaaatg aacaagcaga aagaggcgtg attgattggg aactgacaga
    17461 aaagaaaaca tatgaactgc tgaataaagt cggtttgtct atcgacccga atcttctagt
    17521 atcccagatt ggcgtagggc aacagcaact agttgaaata gctaaagcat tatcaaaatc
    17581 cgtccgtctg ttgattttgg atgagcctac cgctgcattg aatgaagaag aaagcgcgaa
    17641 tttgctgaga ttgatccgag agttgaaaga gcaaggtgta acctccatca ttatttcaca
    17701 taagctgaat gaaatcgtgg atatcgcaga tcgaatcacc attttacggg atggacagac
    17761 gattgagaca ctagaaaatg aaatgatcag cgaagagcat attattcgcg gaatggtggg
    17821 cagagattta gttgatcgtt atcctgaaag aaaaccggat attggagaag tttattttaa
    17881 agtagaagac tggacggtct atcaccctct tgatcacgag cgaatcataa acgaccacat
    17941 caacttgcat ttgaaaaaag gagagattgt aggaatagct ggactgatgg gagcgggcag
    18001 aactgaattc gctatgagtc tatttggaca ttcttatgga agcaagatat ccggacgtat
    18061 attaaaggaa ggggcagaga tatcagttaa gaccgttcct tcagccattg caaacggact
    18121 cgcttatgtc tcggaggacc gaaaatcttt aggactgaat ctgctgatgg atattcggga
    18181 aaacgtgacg ctgagcagtt tggataaaat aagtcaaaaa ggagtattag ataaagaaaa
    18241 agaagtaact gaggcagaaa atttccggaa aaagatgcgt ataaaaacaa actccatcca
    18301 tcaaattgtc agtagtctta gtggtgggaa tcaacaaaaa gtcgttttat ccaagtggct
    18361 gatgacacaa cccgatattc tttttttgga tgagccaacc cgtgggatag atgttggggc
    18421 aaaatatgag atctacacga ttatcgaaga aatggcagca aatggcaaag ctgtctgtct
    18481 tatctcttct gaacttcctg aaatattagg gatgtgtgat cgaatctata cgatgaacga
    18541 aggacgtatt acaggagaag tctcgcgaga agatgcagat caggaagtct tgatgaaatt
    18601 aatgacgaaa gaagaggtgg gttaagttgg aacaggcaaa aaatcttacg gataaaaaag
    18661 agaaaaaact aaatttgaaa agtagagcag ctgatctttt tggtcgctac agcatggtga
    18721 tcattttagc gggactactt attgcgtttc aattgatgac ggatggtatt ttctggcgtc
    18781 cattgaatat aactaacctt gttctgcaaa atagccatat attagtacta gctgcaggga
    18841 tgttattagt tgtgctctta ggtcatgtgg atttgtcggt agggtcagtg atggcgtttg
    18901 ttggtgcaat tgcgggcatg atgatggtca atcgccaaat gaacccgtgg atgacagtta
    18961 tcgcatgtct tgcagtaggc gggctgatcg gcgcatggca aggtttttgg gtagcttatg
    19021 cagggatacc ggcgtttatc gtgactttag caggattgct gatgtttcgt ggactgacac
    19081 aagttgttct aggaggccaa tctctagcac cttttccagc tgttttccaa aaaatgtcta
    19141 cgggttattt accagactta agcgaaggaa gcagccttca cttcttgaca ttgattttag
    19201 gaatgatcat cacgatcgtg ttagttgttg gtcaatggcg aacaagaaat cgtcggaaaa
    19261 atcatttatt tgaagtggaa tctccaacag ctttcttggt aaaggcggta tttacagcag
    19321 tcgttgtact aggaataact tatatctttg cctcttatca agggtatccg attattttga
    19381 tcattcttgg tttgatcgtt gcagcatatg ggtttttgac aaataaaaca gtagcaggtc
    19441 gacagattta tgcgacgggc ggaaatcgaa aagcggctga actatcaggg atcaaaacaa
    19501 agcgaatcac gttctgggta ttcgtcaaca tgggagtcat ggcagcttta gctggattag
    19561 ttttagctgc tcgattgaat gcggcaacac ctcaagcagg tacatcgatg gaactggatg
    19621 caatggcggc agtatatttt ggtggtgctt cgacttccgg cggcattgga acaatcatgg
    19681 gtgcgattgt cggtggcttg gtcatgggtg tattgaacaa tggcatgtcg attttaggcg
    19741 tcggggtaga ctggcagcag gcaatcaaag gattgatctt gcttttagcc gttgtgctag
    19801 acttgtataa taagaaaaaa cgaacaacgt aggagaacgc cggttattca gaaaaaagac
    19861 tgtgacaaga catttgtcac agtctttttt tcgctaaaag cgaacattca ttgtttcgtt
    19921 tgtatagact aaaaataata tatgtttttt taccattcgt ataaattctc tttttgctct
    19981 tgattttttt gcttaattga gttaaattac atagggcgct aaaaaaagcc ttgattaaat
    20041 taataatgtt cgtgttttgc tggatgtgaa catcaggagg ataatgtaat gaaagtattt
    20101 gattacgaag atattcaatt aattcctaat aaatgtatcg taaatagccg ttctgaatgt
    20161 gatacaacgg tcacattagg taaacataca ttcaaaatgc cagtagtgcc tgccaacatg
    20221 cagacgatta ttgatgaaac aatcgcagaa ttcttagcgg aaaatggtta tttctatatc
    20281 atgcatcggt ttgatgaagc agctcgaatt ccgtttatca aaaaaatgaa aaagcgtgga
    20341 ttgattacct cgatcagtgt tggcgtcaag aaagaggaat attcctttat agagaagttg
    20401 gcagaagaat cgctaaatcc tgattatatc actatcgaca tcgcgcatgg acatgctaac
    20461 tcagttattg atatgattca gcatattaaa aaatatttgc ctgaaacttt tgtgattgcc
    20521 ggtaatgttg gtacaccgga agccgtccgt gaattggaaa atgcgggcgc agatgcaaca
    20581 aaagtcggga ttggtccagg aaaagtatgt attacaaaaa tcaagacagg ctttgggact
    20641 ggaggctggc aactggcagc tcttagatgg tgtgcgaaag cagctcgcaa gccgatcatc
    20701 gctgacggtg ggatcagaac acatggcgat attgcaaaat ctgtccgttt tggtgcgaca
    20761 atggtcatga ttggttcatt gtttgccggt cacgaggaat ctcctggcga aacaaaagtc
    20821 gaaaatggaa tcgtgtataa agaatacttt ggttctgctt cagaattcca aaaaggcgaa
    20881 aaacgaaatg ttgaaggaaa gaaaatctgg atccaacaca aaggatcttt gaaagataca
    20941 ctagtggaaa tgcaacaaga ccttcaatca tctatttctt atgctggagg aagagatctg
    21001 gaagccattc gaaaagttga ctatgtcatc gtgaaaaatt cgatttttaa tggagacaca
    21061 atctaaaaaa taaataaaat attaggatgt tgtgaaaaag ttgtcctgca ttaagtaata
    21121 agaacagcca aacaaaaata gttctttata tgttttgttt ggctggaatt attatcgcag
    21181 atacaagctt ttgaacatca ttattcagaa taagggactg tgataagatt tttgtcacag
    21241 tcccttatgt tttgcaaaaa aagtttttct tttttctcgt aaattcggta aaatcaaaag
    21301 aaaaaataga caatagaaaa gagaagctta tgtgggaaaa agtagagaaa aaacaaggac
    21361 cgatttatcg tcaaattatg gaacagatta tgagagaaat cgaaaacgga aggatcaatc
    21421 ctggaagtca acttgaatca gaacgaaaac tagggcaact ttttggtgtg aatcgttcca
    21481 ccgttgtcca tgcattggaa gagcttaggg agcttggggt actaacgagc aaacgtggca
    21541 gcggatggtt tgttaatcag actgaatggg ggaaattcgc tgttccaaga atcgattggc
    21601 ggcaaatgat ctctcctcgt tatgagcaga cggactggta tgagcaaaaa ataagagaag
    21661 caaagcagat ccaaaaaaca tcgtttcttg atttatacgc tagcgagatg ccagatgagc
    21721 ttttgccgaa ttttgagttt ccttcttatt ctcttgaaga aatcttagcg gaagaaaaag
    21781 aaatggatct tttaggctat actccgttac gtaacaaaat caaacggtat ttggaaagta
    21841 aatttgaatt ggcattttcc cccaaccagc ttcttgtgac tggtggcggt cagcaagcaa
    21901 tctttttgat tttacaaacg attctttcag ctggagaggg gatagctgta gagtcacctt
    21961 ctttttttta ccgattacct cttttcaaag cttcaggaac gcgtttattt gggataccga
    22021 tggatgaaga agggatcgac ttagaaaaac tgaaagaatc gatccataaa aataaattga
    22081 aagcagtgct tatcaacccg aattttcaaa accctacagg aaaagtgatg agtcaaaaac
    22141 gacgagaaaa gctagtagaa ttgtgtcgac agtatcggct tccaattatt gaagacgatg
    22201 tatttacgga tctttcattt ctaaaccaag aagaagtcct tcctatacga acgattgatc
    22261 cggataatgt gttatacgtc ggttcgttat ctagggtttt aggaaaaaca acgaaaatcg
    22321 gttgggtgat aggacctgag acttttatct cgcaactagc tcaagcgcaa gaaatgatgg
    22381 agttttcgat gaatatcctt acacaaatca cagtggctaa tgtatttaat gaagcaattg
    22441 atttgaaaat gcaagatgta agaaaaaagt tgaaagaaaa aagccgactg ataagcgctt
    22501 ggggagattc acaatcgttt ttcaagcttc attcaatttt aggtggttac tatgcctgga
    22561 ttacttggga tgggaaaaaa ctagaccccg aactagcaga aaaagtagta gatatgggtc
    22621 ttggaattgc accaagtcta ctttttgggc aagatataaa tggaatcaga atcaattaca
    22681 gtaggctgga tgaaaaccaa ataccgttgt tttattcaaa gatgaaaatt ctagaaaagt
    22741 ggttaacaga ataatttcac aaagtaaata gattaaagaa tataacagct tggatttaaa
    22801 tttcaagctg tttctttttt ttcggaaaaa gaatacgata taaagaaact aagaaaaaac
    22861 cattatttgt acgtccgttc acgatgtgta aataaaataa atgtttgcaa caaaactgta
    22921 taacaccaac gtttttaaat agaaacagat ggttgtaagt ttgattagaa aatagaaaaa
    22981 atgcagatga aatataaaac gctttcctta ttgtgatttt attcactaat gctgttaata
    23041 tgcggattgg cataatttcc tttcatcgtg aaaatttgtg cttttagctt gtatttctca
    23101 taaatccatg ataatttatt aatgaagacg gttaaatagt gatacagttt tattcactgt
    23161 ttcaatcgca gaatgaagag attttcttat agatgagaga ggaatgtgtg acaaatggca
    23221 aacaaaaaag caccgatcga cttccaagca ctgctagatg aagtcaatgc agatttccca
    23281 gtatatcaag cacttgatca agatggaaac gtagttaaca aagatttagt acctgattta
    23341 tccgatgatg aactcgttga attaatgact catatggtat ggtctcgtgt attagaccaa
    23401 cgttcaacag cgctgaaccg ccaaggacgc ctaggctttt ttgcaccaac tgctggacaa
    23461 gaggcaagtc agctggctag tgcttacgca tttgataaag aagatgttct tcttccaggt
    23521 tatcgggatg tacctcaact agtaaaacat ggtttacctt tatctcaagc ttttttatgg
    23581 tctcgaggac atgctgcagg taattcttat ccggaagaat tgaaagctct accaccacaa
    23641 attatcatcg gtgcacaata tgtacaagca gccggtgttg cattaggttt gaagaaacga
    23701 aacaagaaaa atgtcgtctt cacttatact ggtgatggcg gttcatcaca aggtgatttt
    23761 tacgaagcaa tcaatttcgc tggcgcttac catgcaaatg ccgtatttta tatccaaaac
    23821 aacgggtatg cgatctctac acctcgtgaa aaacaaactg cagcaaaaac acttgcacaa
    23881 aaagctgtcg cagctgggat tcctggtatt caagtcgatg gaatggatcc gcttgcagta
    23941 tatactgtat ctaaaatggc acgggaatgg gcgatcagtg gaaatggacc agtcctaatc
    24001 gaaacactga cttatcgtta tggaccacat acactatctg gtgacgatcc aacccgctac
    24061 cgtacaaaag acacagatga cgattggcag aaaaaagatc cattgatccg cttccgtaaa
    24121 tatttgacgg aaaaaggact ttggtctgaa gaaaaagaag aacaagtcat cgaagcaact
    24181 aaagaagaaa tcaaagcagc tattgctgaa gccgacaaag taccaaaaca aaaggtttca
    24241 gatttcttga aaaacatgtt cgaagtatct ccacaatcaa tcaaagaaca aattgcaatt
    24301 tatgaagcga aggagtcgaa ataatcatgg cacaaaaaac aatgatccaa gcaatcacag
    24361 atgccttagc acttgaacta gaaaatgacg agaatgtcgt tgtttttggt gaagatgttg
    24421 ggaaaaacgg aggagttttc cgggcaactg aaggattgca ggaaaagttc ggagaagacc
    24481 gagtattcga tactccttta gctgaatctg gaatcgcagg attgagtttc ggtcttgcgt
    24541 tagaaggatt tcgtccagtt cctgaaatcc aattctttgg ttttattttc gaagcaatgg
    24601 acgaagtagt agctcaaatg gctcgtacaa gatatcgaat gagcggcact agaaatctac
    24661 ccatcacaat tcgttcgcca tttggtggcg gtgttcatac accagaattg cattcggata
    24721 atttagaagg tttgatcgct cagtctcctg gtattcgagt agtgattcct tccaaccctt
    24781 atgatgcaaa aggactattg atttcttcta ttagaagtaa cgatccggtt gttttcctag
    24841 aacacatgaa actatatcgc tcattccgag aagaagtgcc ggatgaagct tacgaagttc
    24901 ctttggataa agcagcagtt actcgtgagg gaacagatgt atctattatc acatacggag
    24961 caatggtgcg tgaagcaatc aaagcagcag acaatcttgc aaaagaaaat atatctgttg
    25021 aaatcattga tcttcgtaca gttgcgccat tagatgtaga aacgatcatt caatccgtgg
    25081 aaaaaactgg tcgcgtagtt gttgtccaag aagcacaacg acaagcgggc gttgccgcgc
    25141 aagtagtttc tgagatctca gaacgcgcta tcctttcatt agaagcccca atcggacgag
    25201 tttctgcacc tgatacagtc ttcccatttg gacaagcaga aaatgtctgg ttgccaaatg
    25261 caaaagatat cgaagacaaa gtaaaagaaa tcgcggaatt ttaagaaaag aagggacgaa
    25321 acaaagtcat ggcttatcaa tttaaattgc cggatatcgg tgaaggaatc gcagaaggtg
    25381 aaatcgtcaa atggttcgtc aaaccaggag atacgatcaa tgaagatgat acattactag
    25441 aagttcaaaa tgacaaatca gtagaagaaa tcccgtcacc tgttacagga acggttaaaa
    25501 atgtgattgt tccagaaggt accgtagcaa atgttgggga tgtattagta gaaatcgatg
    25561 caccaggaca cgaagacaat gaaggggaca gtggtgtagc cgcagaatcc caaactccag
    25621 ctaaaccggc tgctgaaccc actgttgata cagaatcagc tggatcgtca agcgaaggag
    25681 tcttccaatt taagttaccg gatatcggtg aaggaatcgc agaaggtgaa atcgtcaaat
    25741 ggttcgtcaa accaggagat acgatcaatg aagatgatac attactagaa gttcaaaatg
    25801 acaaatcagt agaagaaatt ccgtcacctg tcacagggac agttaaaaac gtgattgttc
    25861 cagaaggcac tgtagcaaat gttggggatg tattagtaga aatcgatgct cctggacaca
    25921 atagtgcacc gtcaactagt gcgccatcag ctgaagcacc aaaagaaaaa gtggaaacat
    25981 caggttcagc aagtgtcgtt gaagctgccg atccaaataa acgtgtattg gctatgccat
    26041 ctgttcgtca atttgcccgt gaaaaagatg tagatatctc acaagtaact gcaactggaa
    26101 aaggtggcag agtaacaaaa gaggacatcg aaaacttctt ggcaggtggt ccaagcagtg
    26161 caccagcgaa atcagaagcg ccagaagcgg cagcaccgaa agaagcagct cctgcagcag
    26221 aaagcaaacc agctgcacca gcaaaaccat tcaagtccaa cttaggagac ttggaagaac
    26281 gtgtagcaat gacgccaaca cgtaaagcta tcgctaaagc aatggtcaac agtaagcata
    26341 cagctccaca cgtgacattg catgatgaag tagaagtgtc taaactatgg gataatcgga
    26401 aacgatttaa agaagttgct gctgcaaatg gtacgaaact tactttcttg ccatatgtcg
    26461 tgaaagcttt aacagcgact gttaagaaat acccagtatt gaatgcatct atcgacgatg
    26521 caaaccaaga aatcgtttat aaacattact acaatatcgg tattgcaact gatacggatc
    26581 acggactata tgtaccaaat gtgaaagatg cagaccgcaa aggaatgttt gctattgcag
    26641 acgaaatcaa tgagaaagca aaattagctc atgacggcaa actatctgca gaagatatgc
    26701 gcaatggaac aattacgatc agcaatatcg gatctgtagg tggcggttgg tttacaccag
    26761 tcatcaacta tccagaagta gctattttag gtgtaggaac gattgcacaa caaccaatcg
    26821 taaatgctga aggcgaaatc gttgtcggtc gtgtgatgaa actgtcatta agtttcgatc
    26881 accgtatcgt agatggagca actgcgcaac aagcaatgaa taatatcaaa cgtcttttag
    26941 ctgatccaga gctattaatg atggaaggat gataaacaaa tggtagttgg agattttgct
    27001 gtagaattag atacagttgt aattggtgcg ggacctggtg gctatgtagc tgccatccgc
    27061 gctgctgaaa tgggacaaaa agtagcaatc attgaaagag agtatattgg cggtgtttgt
    27121 ttgaatgtcg gctgtattcc ttcaaaagca ctgatagctg caggacacca ttatcaagag
    27181 tcactagatt ctgaaatgtt tggagtaact agtgaaaacg tcaaactaga ttttgcaaaa
    27241 acacaagaat ggaaagaaaa caaagttgtc catacgttga cttctggtgt tggtttccta
    27301 ttaaaaaaac ataaggttga aacaatcgaa ggagaagcgt tcttcgtaga tgatcacaca
    27361 ctacgcgtca ttcatccaga ttcagctcaa acttattcgt tcaataacgc aatcatcgca
    27421 acaggttccc gtccaatcga gattccagga tttaaattcg gaggacgtgt gttagattct
    27481 actggcggat tagcattgaa agaagtacct aagaaatttg tgatcatcgg tggcggtgtg
    27541 attggtgccg aattgggcgg agcgtacgca aacttaggag cagaagtaac gattcttgaa
    27601 ggctcaccac aaattttacc aacttacgaa aaagatctag taaaattagt agaagatgat
    27661 ttcaagaaaa aaggcgtaac agtcgtaacg aatgcaatgg cgaaagaagc agtcgataac
    27721 ggtgacagcg tgacagtgaa atatgcagtg gacgggaaag aagaatccgt tactgctgat
    27781 tatgtgatgg tcactgtagg tcgtcgtccg aatacagatg atatgggctt agaacaagcg
    27841 ggtgtcgaag taggagaacg aggattgatc acggtggata aacaaggacg tacgaacgta
    27901 cctaacatct atgccatcgg tgatatcgtt ccaggggcgg cattagcaca caaagccagt
    27961 tatgaagcaa aaatcgctgc tgaagcaatc tctggcaaaa aagtagctgt agattataaa
    28021 gcaatgccgg cagtagcctt cactgatcct gaattggctt ctgtaggtat gacgatcaaa
    28081 gaagcaaaag atgctggtat cgaagcaaaa gcatataaat tcccattttc agggaacggt
    28141 cgggcattat cgcttggtaa aacagaagga ttcatccgtc tagttacgac gatcgaagat
    28201 aacgtgctta ttggcgcgca aatcggtgga gtcggcgcaa gtgatatggt ctctgaatta
    28261 gctttagcaa tcgaatcagg aatgaatgct gaagatatcg ccttgacgat tcatcctcat
    28321 ccatctcttg gcgaaatcgt catggatgct tcggaattag cattaggttt accaatccat
    28381 atttgatttg aataatacag gcgaaacgca actgaaaaat cagttgcgtt ttgtttttta
    28441 gaattatcaa taatattatt atgtaaactt aaaaatatga caacttcttg gtttattacc
    28501 acttcctatg ctacactgaa gaggaatatg aaataggaga gttgaagatg caagaatatc
    28561 agtatccact tgatttagat tggacaacag acgaaatggt cattgtaatg aagatgtggg
    28621 aagatctgga acgtgcgaat gaaaaaggga taaacaatga agcttttttg aagacttatc
    28681 agcagtttaa aactgttgtc aaatccattg gtgaggaaaa acgattggga cgggaatttg
    28741 aaaaagcttc cggttattct ttatatcgta cagtgcagca agcaaaaaaa aatccaaaca
    28801 aaactttgag aatgaacggg tgagataaat ggaacagatg attgatcata tcaagtcctg
    28861 gcttgaagaa gctggtgaga aaatcaaatc ttctcaacaa acattaacaa tctcgcaaaa
    28921 atcaaatcga acggatctag taacaaatgt cgatcgaaac atccagaatt ttctaatcga
    28981 aaaaatccat tcctttgatc cagaggcgaa aatattggca gaagaagaag ggtgtaatca
    29041 attatcggat ctcgatggaa gagtctttat catcgatcct attgatggca ccttgaattt
    29101 tgtgattgaa ggggaaaatt tttgtattat gctcgctgtt tatgaatccg gcgttggaaa
    29161 gcttggtttc atttatgacg tgatgagaaa tgaacttttt tggggtggaa aaggaatagg
    29221 cgtgtataaa aatgatgagc cattgcctag accagcaaat aaatccttat cggaaggctt
    29281 acttggtgtg aatagttatc ttttcggtca taataaatat ggaatccgag aaattgcgga
    29341 aagcagcatg gggacacgta tgtacggatg cgctggtctt gaactagtgg caatcttgaa
    29401 aggaaaccac attgcttata tttcaaacct tagcccttgg gattatgcag cgggaaatgt
    29461 cttattggaa gagtttggta tggtaacaag cggtcttttt ggtactcctt tgacatttga
    29521 aaaaagggaa tactatttag cagggacttc ttgtgcatat gcagaaatcg cagacctttt
    29581 gaaaaaagaa ggctgaaaaa aaggtagaaa tcattcacaa aaatgataaa aacgagcaaa
    29641 agattaattt tctcgaaaaa atgaaaacat tttactatat ttcatgaaaa aagtctgcta
    29701 taattagcag tcgagtaaaa tttgccctgt cataaagaac caataaaaaa ggagttagtt
    29761 acattgaatt atagaaacga tatccgtaac gtcgcaatta ttgcccacgt tgaccacgga
    29821 aaaacaacat tagttgatga actattaaaa caatcagata cattagacgc acatacgcaa
    29881 ttgcaagaac gtgcgatgga ctcaaatgcg ctagaaaaag aacgtggtat cacgatttta
    29941 gccaaaaaca cagctgtaga ctataaaggt attcgcgtaa acatcatgga tactccagga
    30001 cacgcggact tcggtggcga agtagaacgg atcatgaaaa tggttgacgg cgttgtgttg
    30061 gtcgtagatg cgtatgaagg aacaatgcct caaacacgtt ttgtattgaa aaaagcactg
    30121 gaacaacata tcacaccaat cgttgtcgta aacaagattg acaaaccttc tgctcgtcct
    30181 gagcatgtcg tagatgaagt tcttgaacta ttcatcgaat taggagcaga tgatgatcag
    30241 ttagactttc ctgtgattta tgcatctgca ctaaatggta cgtcaagctt gtcagatgat
    30301 ccagcagatc aagaaccaac catggcacct atttttgata caattattga aaaaatccct
    30361 gctcctgtcg ataacagcga cgaaccatta caattccaag tttcattact tgactacaac
    30421 gattatgtag gtcgtatcgg aatcggacgt gtatttagag gaacaatcaa agtaggagac
    30481 caagtagcat taattaaatt agacggaaca gttaagaaat tccgtgtaac gaaattattt
    30541 ggtttctttg gactaaaacg tctagagatt caagaagcaa aagctggaga cttgattgct
    30601 gtctcaggta tggaagatat ctttgtcggt gaaacagtta ctcctgtgga tcatcaagat
    30661 gcgttaccta tccttcacat tgacgaacca acattgcaaa tgactttctt agttaataat
    30721 tcaccatttg ccggtcgaga aggtaaattc gtaaccgctc gtaagattga agaacgtttg
    30781 atggcagaac ttcaaacaga tgtatcctta cgagttgaac caacaaactc tccagatgca
    30841 tggacagttt ctggtcgtgg agaattgcat ttgtctatct tgattgaaaa catgcgccgt
    30901 gagggatacg aattgcaagt atctcgtcca gaagttattg aaaaagaaat cgacggtgta
    30961 aaatgcgaac cgtttgaacg cgtgcaaatc gatacaccag aagaatatat gggtagtgtt
    31021 atcgagtcct tgagcttacg taaaggtgaa atgcaagata tggtccatac aggaaacgga
    31081 caaatccgtt tgacattctt aacacctgcc cgcggtttga ttggttattc aactgaattc
    31141 ctttcaatga cacgtggtta cggaatcatg aaccatactt ttgaccaata tctgccaatg
    31201 cttcctggtc aaattggcgg acgtcaccaa ggggcgcttg tttcgatcga tacaggaaaa
    31261 gcaacgactt attctatcat gagtatcgaa gaacgcggta cagtcttcgt agaaccaggt
    31321 acagaagtat atgaaggaat gattatcggg gaaaacagcc gtgataatga tttgactgtc
    31381 aacatcacga aagcaaaaca aatgacaaac gtacggtctg ctactaaaga ccaaacatct
    31441 gtcatcaaaa aaccaaaaca attgacgttg gaagaatctt tggaattctt gaatgatgat
    31501 gaatattgcg aagtaacacc agaaagcatt cgcttgagaa aacaaatttt agagaaaaat
    31561 gctcgtgaaa aagcatctaa aaagaaaaaa taatctgtaa aaggatgaag agagaaacca
    31621 gcttgttata aaaaatagct ggtttctttt tttgtccaac tcttttctgt ggagaagtca
    31681 tctttgtcaa tggacataaa ttcagaaaat acgccgaaag acgtttaaaa gacttttaaa
    31741 aaacttattt ctagagagtt tttgtttcat aataagataa tgtttcacga aaggagatca
    31801 acttgtcctt cgaagaaaat cgaagtaaaa tggcaagaga aaggagcggg aagatgaacg
    31861 acttattaaa acaatacttt ggctatgatg agtttagacc tggtcaaaaa gaaattatcc
    31921 agaaagtcat tgatcaggaa aatgtattag gaatcatgcc taccggaagt gggaaatcaa
    31981 tctgttacca gcttccagct ttactattag atgggcttac tgtggttgtg tcccctttaa
    32041 tctctttgat gaaggatcag gtggacgcgg cgaatcaatt aggtataccc gccactttta
    32101 tcaatagctc gttagatggt tacgaaacag ctagacgctt ccaagaaatc gatagacagc
    32161 agtaccgttt actttatatc gctcctgaac gttttatcat gccggatttt atccaagcaa
    32221 tgaagcgatg gaacgtccgt atgatcgcta ttgacgaggc acattgtatc tctcagtggg
    32281 ggcatgattt ccgcccaagt tatttacaga tggcgaacca gctagatcaa ctgccaaatc
    32341 gtcctgtaat tgttgctttg acagctacag cgactgtgca agtagctgct gacataaaaa
    32401 gacttttaaa aattccagaa aacaaccata ttcagactgg ttttgaacga gaaaatctac
    32461 gatttcaagt aattaaagat caaaaaaaag aacaatatct aatcgaatat ttaaagatca
    32521 acaaaaatca atctggtatc atttatgcag caacgagaaa agaagtagac cgtctctatc
    32581 atttgcttaa aaaattcgat ttttccgtgg gtagatatca tggtggtcta aatgagaatg
    32641 agcgaacaga aatgcaagaa gcctttttat acgatcgctt gcagctgatt gtagcgacaa
    32701 atgcatttgg tatgggtata aataaaagca atgtccgttt tgttatccat tatcaaattc
    32761 ctggctctct agaagcatac tatcaggaag ctggtcgggc gggaagagat ggtctttcca
    32821 gtgaagccat cctgcttttc tctcctcaag atatccaagt ccaaaagttt tttatccagc
    32881 agtcccaaag agaagaaggg caaaagcaaa aagaatatga aaaattaaaa gcgatgacag
    32941 aatacgtgta tattgagtcc tgtcttcagc aatacatcct aaactatttt ggcgagacaa
    33001 gcagtccgtg caaccgttgt ggtaactgtt tagatgacag agaaatagta gaagtaacga
    33061 cagaagcaca gatggttctt tcttgcttaa aacgtatggg tgagaactat ggtaaacaaa
    33121 tgctgatgaa agtcttagca ggatcgaaag aacaaaagct gcaagcttta ggttttggac
    33181 atttatctac ctatggactg atgaaaaacc aatcgcaaaa agaaacgatg cagttaattg
    33241 aatatttgat atcgaatggc tatcttctga ccatcaatgg tgagtatcct gttttgaaag
    33301 taacagaaag agggatacaa gtattgaaag gacaagaatc tgtttatcga aaggaaccca
    33361 agaaagtcca gcagctatcg gatgaagaaa ccgatacact atttgaagtg ctgcgggaac
    33421 tgcgaacgga tctagcatca gaagcaggcg ttcccccgta tgtcgtattt tcagattcca
    33481 cattgaaaga aatgagccga atacgtccat caagcagatt ggagatgctt cagataaaag
    33541 gagttggcca aagcaagctt gataaatatg gcgaagcctt tttatctcgg ataaaaaatg
    33601 cggactctaa cgttctggat aagtagaaag aacgaatacg taaaaatgaa taaaaacaac
    33661 tggttaaatc tgtttttttt gctccttatg aaaatcaaat atgttataat taaggaatta
    33721 gaatgggagg taagcacaga tggattcttt gtcgaaaaaa cttgcgatcc aagtattaaa
    33781 tgatgaagca gaacggatca aacgattaat ccgaaatcaa aacaacagtc tctgtatctc
    33841 acaatgcaaa gccttcgaag aagtggtaga tacacagatg tacggctttt cccggcaagt
    33901 cggttttgct gtccgtatag gagtaatcgg aaagaacgag ggccagctga tgttaagtga
    33961 gctagaacga gaattgaatc agttatatag tgaggtttac caagaaattt atgataaaaa
    34021 agaagttggc aaggaggaat agacttgcct aagaaagtga aaaaaaggca tctattagac
    34081 tatagcatct tgattcccta tttaatttta tgtgtattgg gattgatcat ggtatatagt
    34141 tctacgtcgt atctattatt agaaaacgga caaaatccgt ccgcatcagt cattaaccag
    34201 agtatttttt gggtgcttag cttgattgct atcgcactac tttataaaat gaaaacagat
    34261 gttttgaaaa accagcgttt gatcatggca gccatcgcag ttttgacgat tttgctgctg
    34321 attgttgtgt tttttggtaa ggagatcaat ggggcgaaag gttggctgca aattgcagga
    34381 ttctcgatcc aacctgccga atacctaaaa atcatttcta tctggtacct gtctctgact
    34441 ttatctaaaa gacaaaacag tgtacaaaaa gattttcttg ggactgtgaa acgtccactt
    34501 gcaatggtta tcggacttac tgcattagtc gctattcttc ccgattttgg taatgcggca
    34561 gttatctttt tgattatttt ggttctgctt ttagccagcg gagtcaatta tgtgtatact
    34621 ttgattgtag gagtaggagg cttttgtcta agtactttta cgatctggct gatcaatatc
    34681 acaaacggaa agatcttacc cggacgttta cagtatatct ataatcgatt tgctatttac
    34741 caaaatcctt tctcagacga attaaataaa gggcatcaac tagtcaacgg ctactatgcc
    34801 atgttcaacg gaggactatt tggcagggga ttaggtaaca gtatccagaa aaaaggattt
    34861 ttacaagaag cacaaaccga ttttatttat gcaatcgtag tggaagaact gggagtgatt
    34921 atggggattt tgatattagc gttgctattc tttatgattg tgcgcattgt ccttgtaggt
    34981 atccgttcaa aagatccgtt caattcgctt ttgtgcattg ggatcggcgc aatgtttttg
    35041 atccaagtat ttgtcaatct tggaggaatt actggcgtta ttcctttgac agggatcacg
    35101 ttcccatttt taagtcaagg aggctccagt ttgctgatgc tttcgatttg tgtcggcttt
    35161 gtcctcaaca tcagtgcgga tgaaaaacgc aagagcttag gtttataata aaaaaagatg
    35221 taggagtggt tcgatgaaaa aagttttagt tgctaacagg ggtgaaatcg ctgtacgtgt
    35281 atttcgtgct tgtacagaat taggaattaa aactgttgga atctatgcag aagaagatga
    35341 atattccgta caccgtttca aagcggatga agcatattta gtaggacaag gaaaaaaacc
    35401 gattgatgcg tatctagata ttgaagggat catttctatc gcgaaagaat gcggagctga
    35461 cgctattcat ccgggttacg gtcttttgtc ggaaaacttg aattttgcgc aacggtgcga
    35521 agaagaaggc atcatttttg ttggacccaa actgcatcat ttagatattt ttggagataa
    35581 aatcaaagca aaagctgcag ctatcgaagc ggggattgct tcgattccag gcacagatgg
    35641 accaatcgct tctatagacg atgccttgga gtttgcgaaa caatacggtt atccgattat
    35701 gatcaaggca gctctaggcg gcggcggacg cggcatgcgt gtagctcacg atgaaaagag
    35761 tgcaagagag ggctacgaac gtgcgaaaag cgaagcaaaa gcagcctttg gtagtgatga
    35821 agtgtatgtt gaaaaataca tcgctaatcc taagcatatc gaagtacaga ttctcgggga
    35881 tacgcatgga aacgtcatcc atctttttga aagagattgt tctgttcagc gccgtcacca
    35941 aaaagtagta gaagtagcgc cttgtgtctc tatgaatgaa cagcaacgtc aaaaaatctg
    36001 ccaggcagct gtccaattga tgaaatatgt cgggtatgtc aacgcaggta cagtagaatt
    36061 tcttgttgaa ggagatgatt tttactttat cgaagtcaac cctcgcgtcc aagtggaaca
    36121 tacgatcaca gaaatgatta cagatattga tatcgtaaca acgcaactgt tgattgctca
    36181 aggtttggat ctgcataaag aaatcggatt gcctcagcaa gaaggaatta aattaaatgg
    36241 ttcagccatt caatgccgaa tcactacaga agacccgttg aataactttt taccagacac
    36301 agggaaaatc gatacgtatc gttcacctgg tggttttggc gtacgtctgg atgtcggaaa
    36361 tgcttacgcg ggctatgtag tgacaccgta ttttgattca ttgctagtaa aagtatgtac
    36421 gcatggtgct acctttgaaa cagccattca gaaaatggaa cgttgcttga aagaatttag
    36481 aatccgtgga gtgaaaacaa acattccatt tatgctcaat gtcatcacac atcctgaatt
    36541 ccaatcagga aatgcaaaaa caaccttcat tgatagtaca gcaacattat ttgaatttcc
    36601 tcgactacga gaccgcggaa acaaaacgat gaaatatatc ggtgaaatta ctgtgaatgg
    36661 ttttccaggt atcgaaagtg gcgaaaaacc attttatgaa gaaccacgta tgcctaaaga
    36721 tctaatcaca agaactgatt acgtaacggc taagaatgta ttagatgcga agggtgccga
    36781 tgctttggtc gaatggatca aaggacagga aaatttgttg ttgacggata cgacatttag
    36841 agacgcccat caaagtctgc tagcaactcg tgttcggaca aaggatttca agcagattgc
    36901 acgtttgact ggagaaggtc ttcctgaact cttttcaagt gagatgtggg ggggagcaac
    36961 atttgatgtg gcttaccgct ttttgaatga agatccttgg caacggttga gaaaaattcg
    37021 ttctttaatg cctaatacgt tgctgcaaat gcttttcaga ggttcaaatg ccgttgggta
    37081 ttctaattat cctgacaatg tattggtgga atttgtcaaa gaagcagcag cgcaaggaat
    37141 cgatgtattt cgaatctttg atagtttgaa ctggactcca caaatggaaa aaagtatcca
    37201 agctgtacgg gatactggta aaatcgcaga ggcagctatt tgctatactg gcgatatcaa
    37261 cgatccaagt cgggcaaaat acaatgttca gtattataaa gacatggcaa aggaactaga
    37321 acaactgggt gcgcatatca ttgcaatcaa agatatggct gggctgctta aaccgcaggc
    37381 agcttatcgt ttgattagtg aattgaaaga aacgacagat ctgccaatcc atctgcatac
    37441 tcatgatacc agcgggaatg gaatcatcac ttattctgct gcttcaaaag caggagtaga
    37501 catcgttgac gtggcaatga gtgcaatgag tgggaatact agtcagccta gcatgagcag
    37561 cttgtattat gcactggtca atggtccacg gctgccagaa atcacgattg aaaatgcaca
    37621 gaaattaaac cattattggg aagatgtgcg catgtattac aaaccgtttg aaaacggctt
    37681 gaatgctcct gaaacagaag tatatatgca tgaaatgcca ggaggacagt attcgaatct
    37741 acagcaacag gcaaaagctg tcggattagg tcatcgctgg gatgaaatca aacaaatgta
    37801 tcatactgtc aacttgatgt ttggcgatat cgttaaagta actccatcat ctaaagtagt
    37861 tggagatatg gcactattta tggtccaaaa tgatcttaca gaagaagata tttatgaaaa
    37921 aggcgaaaca ctaagtttcc ctgaatctgt tgtgactttc ttccaaggag aactagggca
    37981 acccgttggc ggatttccta aaaaattgca aaagattatt cttaaaggca gacctgcatt
    38041 gaatgaacgt ccaggtcttt tggctgaatc agtcgacttc aacgaagtaa aaaaagaatt
    38101 ggcagaaaaa attggctatg aaccaaaaca agacgaagta ttaagctatt tgatgtatcc
    38161 gcaagtcttt ttggactatc aaaaagcata taatcaattt ggcgatgtta cattactgga
    38221 cacaccaaca tttttccaag gtatacgttt gggtgaaaca atcaatgtac aaatcgaacg
    38281 cggaaaaacg cttatcattc gtttagatga aatcggagaa cccgatatcg aagggaatcg
    38341 cgtactgttc ttcaatttga atggacaaag acgtgaaatc actatcaaag ataattcgat
    38401 catcagtacg gtccaaaccc gattgaaagc tgaaccgaca aaccgagaac aaattggagc
    38461 aacgatgtct ggttctgttt tggatgtatt agtgaaaaaa ggcgataacg ttaaaaaagg
    38521 tgatacgttg atgattactg aagcgatgaa aatggaaacg gccatcgaag cacgttttga
    38581 cggagaagtc gcacatgtat atgtgtcttc aggagacact atttcgtctg gtgacctttt
    38641 gattgaagtg actgagaaat aataagcgaa aggtggggaa acatgaaaag actgggtttg
    38701 ttttggctga ttctgctatt agttattgtg gcattctaca tggaaccagt cttgtttccg
    38761 ccaaaacttg aagtgaagga aaactctgat caacaaatat caaaccaaat gacaacgtgg
    38821 aaataccagg agcttaaagc aactggtttt tctacttata tcggaaaacc gatcgatcag
    38881 ctggaaaagg attttggcca agcctatgat cgattaacta gcggatttgg ttttgaaaca
    38941 agatattatg aaaataaagc tagtcatctc acatttgaag cgaacatcca agacagcaga
    39001 gtcacaactg ttaaagtact gcaaacaggg cctgctgata tcgcgccgtt ttatttaggg
    39061 atgacgatgc aagatcttac gaaaatcact actatctata ctaatttcac ttttgagtac
    39121 catgatacag aagttggaat cgaactaatg gaagaggata tgaattatcg tccgctaatt
    39181 gcttttgata acgacacttt tgctatttta ttttttgatc aaacaacaaa cggcctattt
    39241 tcagttgtgt atttagataa agatagtctt ttgaaactat tgccatatca agtgtttggt
    39301 gaaggccttc cacattatca agcagataaa tcggctgatt gggaatcaat caatcgcgtt
    39361 aaagaacgaa aaagtacgac tttattaaat atgcttagaa gagaagacga acttcccata
    39421 tacaatcaaa cacttgcctt tcaaaaccac agtcagctgc tactacatga ttttttgaca
    39481 aggcctgagg aaatattgtc agaggaacgt atggctgatt ggcaaaaatc gctaggcagt
    39541 gctcaaacga cagtgaaatt ctcactgacg aatgatgaat tggagaagtt aatcagtaaa
    39601 caaaaattag aaaatactag tgggctattt attcatccgg cgattgacgc tactttttcg
    39661 tttttatatt ggtacagcga tccttacaac catgaccgtt tcatggaccc gggaacggat
    39721 tctgtaggca ttgctttttc taaagaaaat atgttagtct tattgcaaga agaaaacgga
    39781 gaaagtagtg atagcagtga tcgttaacga agagctgttt caactggagg atcaatgcct
    39841 ccaagtcgct gaaatgataa aaaagagtaa aacgatggct tcttatcttg aacataaaca
    39901 gtcaatggaa gaatctgcaa aagtttgcca gttgaaagaa gcgttcttgt ctaagaaaga
    39961 agcatttgaa aatgtagcgg catatggtga gtatgcacct gattatcgtg aaaaaaaacg
    40021 agctgttcga aaagcaaaaa gacagcttga tatggatgag catgttgcag ctttccgata
    40081 tagtgaaaca cagctgcaaa gtctgttgga tcaaattgtc caagtacttg ccgaagaagt
    40141 ttctaatgaa atcaaagtag atgcaggtag cccgtttttt gaaacgaaaa aacactttgg
    40201 atgcggaggt aattgtcatg caattagaca atagtgaatt tgaaataaca aaacgacgcg
    40261 ggctgatcgt atgggtctac agcttaaaac aattaaagaa tctgaaaaag ttcggcttgt
    40321 tgcattatgt ctcaagaaga atgaaatatg tcgtgcttta cttaaatgaa gagacattgg
    40381 aagaaacaga agaacgaatc cgtaaattac attttgttcg aaacgtagaa cgttcttacc
    40441 gaccggatat cgaaatgaat tttgccgaaa aaataggaaa caaaacagta ttaaaagacg
    40501 aaggtttcga aattgaagag ctaaatacag aaatccgatt agctgaacat ctttaaaaat
    40561 ctcttatgag cagtttttaa ataaaaaata acttggataa cgatcgattt ttgatcattg
    40621 tccaagtatt tttttggtat actagtacca gtaccatttc taaggagtga gtagatgcgg
    40681 ataatatcag gaaattatgg cgggcgccgt ttaaaaagtt tagcaggggc gaacaccaga
    40741 ccaactacag ataaagtaaa agaatccata ttcaatatga ttggaccata ttttgatgga
    40801 gagacagtat tggatctgtt tgcaggaagc ggtggtttag ctatcgaagc agtatctaga
    40861 ggctgcagtc atgcggtatg cgtagacaaa aattaccaag cgctaaaaat catcaaagaa
    40921 aacatcgaaa ttacgaaaga accagagaaa tttaccacaa taaaacttga tgcggacaaa
    40981 gcaatcgaac ggctagcagc ggagaaacaa caattcgact acttgtttct tgatccgcca
    41041 tatgcaaaac aaaaaataat cgatcaaatc cataaaatgg aagaactggg acttttttct
    41101 aaaaccgcag ttatcgtatg cgaaacggat aaaacagtcg aattgccaga aactgtggct
    41161 ggattccatc aaataagaaa acagatttat ggcataacgg ccgtaactat ctatagaaaa
    41221 gagggaaatc aatgaaacgt gcattattcc caggaagttt tgatcctttt acaaaaggtc
    41281 acttagatac ggtggaacgt gcggctaaat tattcgatga ggtagtaatt ggtgttttta
    41341 tcaatacttc aaagaaaagt ttgtttcccc cagaagaaag aatgacattg atcacaaaag
    41401 ctgtttctca tcttcctaat gtaaaagtca tgcatcaaga aaatcaattg acggtagaaa
    41461 cagcaaaaga gattggtgca gatgcgttga tcagaggcat acgaagtatc aaagactttg
    41521 aatatgaacg agagattgct cagatgaatc atcatctata tgatgaattg gaaactgtct
    41581 tcttattagc aaaaccagaa tatagtcacg tgagttccag tattttaaaa gaagtactgc
    41641 actttggcgg agatgtgagc agctacttac cgccagtgat caacgaagct ttagctggaa
    41701 agcgtgaatc aaatgaaagc taaacaatgg ttgaaaacag tactgattat catatttgga
    41761 atgttgatca ttggatttgt agtagttccc ttgccgtatt atgtagaatc accgggagcc
    41821 acgatcgatc tgaaagaact aattacggtc aatgataagg aagataaagg ttctgggtct
    41881 ttctctctta cctctgttgg tatcaggcaa gctacaggtt tcttagcttt aaaagctaaa
    41941 atgacccctt ttgaagaatt gatcagtgaa gaagaattga ctggtggggc gacaaatgaa
    42001 gaatataatc aaatgcaaca gtattatatg gattcttccc aaaatgcagc aatcgaacaa
    42061 gcgttaaaac ttgcagacaa gccttataaa atggaattca aaggcgtata tgtcatgagt
    42121 gtagagaaaa catcgaattt ctttggcaag ctttcagttg gagatacagt aacaaaagta
    42181 gacgggaaaa gctttcaaag tacagaagca tttatggatt atgtaaaaag ccaaaaagtt
    42241 ggacaaacaa tcgaaatcag ttatttgcat aatggtgaag aaaaaacagc ttctggtgat
    42301 ctgatcgagt taccaacaga taaaaaggca ggaataggta tcacgcttac tgaccatacc
    42361 gagatcgaat cagatacaga tgttcgtatt aattctggct ctatcggtgg gccatcagcg
    42421 ggattgatgt tcactttaga aatctatgaa caagtcactg gtaaaaactt gcgacatggt
    42481 aagcaaattg caggaactgg aacgatcaac agtgaaggag aagttggccg aatcggagga
    42541 atcgataaaa aagtggcaag tgcggataaa gctggcgtag agattttctt tgcaccagat
    42601 gatacgattt cagacgatgt taagaaagaa tatcctgaaa taaaaaccaa ctacgaagaa
    42661 gcaaaagctg ccgctaaaaa attgaattcc tcaatgaaaa tcgtaccagt aaaaacagta
    42721 caagaagcgc ttgactatct agagaaaatg aaatgaaact aaataattaa agaggggttg
    42781 tgacacgagt tctgtcacaa cccctctttt tcgtcaaaaa tcttcacgat aaaaataaaa
    42841 acaaaagaaa aaattgacgt aattagatgt tgaagggacg attttgccag agctcactgt
    42901 ttcttcaatt ttaaatgaaa ggagtaatga atgattttta ctggtcattc tttgaaaaaa
    42961 gaacaatgat agaaaaaatc agcaagaaaa tactagcttc acccaaattg atcatttgga
    43021 tgtctatgat agttcttatc ttttgtatcg caagtggttt tttattatca aatttgctat
    43081 tttatagaga aacagaagag actgctgcaa aagaaatact ttcttcgttt agttccagtg
    43141 gagaagatcc atcagctgaa ggaaacgatg tagaagagga tgctcgtcca aaggtcatgt
    43201 acaccgatat caaaggaagt gtgaaggagc ctggtatcta ttccttttct tcagaagaac
    43261 gggtctatga tgtactaaag cgtgcaggtg gattattaga agaagcggat agcgatcgaa
    43321 tcaacttttc tgcgaagata gaagatcagc aagtcctata tatccctgct gtaggtgaag
    43381 agctgccaga acatcttgat cagttggcat cctcggaagg aaaacagcct acagcagatt
    43441 ccgagcctcc caaaataaat atcaatacag ccactccatc agaacttcag cagattcctg
    43501 ggatcggatc agtcaaagcg caagaaatca ttcgatttag agaagaaaac ggatccttcc
    43561 agaaagtgga agacctgcag gagatttctg gtatcggtga aaagacagtt gaaaaactaa
    43621 aaaacttcgt tacaattaaa tagaatgatt caaaatcgac tggcacgagc aataaatgga
    43681 cgctaatgga tactaagaat aatccaattc taagagcttg gcaggacgag gaggtagtat
    43741 ttttggatag gaaatagctt gattgttcgc aaagaaacat taaaaaaacc aatgctgaat
    43801 gtctatctcc aaaataaaat atctgggatt catattatga atacggctgt cagcggcaat
    43861 aacagtcaag ctctacgaga acgctttgcc aaagatgtac ttagctatac agcagataaa
    43921 gtatttattc tcattgggac gaatgatcta gcagagcata aacaactttc taaagaaacg
    43981 taccaaaaaa tctgcagtgg atgatagttc agctgaaaaa agactatagt tctgatcatg
    44041 ctttctttat cacgccacca gcagtcgatg agacaaaaca aaaatatcgg aataacaagt
    44101 tgatcaaaga atatatctct gttctcacag aagtagcaaa acgccatgat tgtgaagtat
    44161 cgatttttat acggaatttc ttgaacaaat ggattcgaag aatttttata atgggctaat
    44221 ggatgacgga cttcatttcg gcagtgaagg gtaggatctt ttgtcagaca ggatgattcg
    44281 ttatatttaa agaatatttt gtttaagcaa tgagtacttt ttaatcaact tgaaaaaacg
    44341 gaggaatata aaacatgtta gaaaaatctt caaaagcatg cgatacgaat aaagaaaaag
    44401 ttactgataa gtcacataat gaacgcattc cttgggacca gtactttatg gctcaggcag
    44461 tactgttatc tttacgtagt acgtgtacac gtttagaagt aggagcgaca ctcgttcgag
    44521 aaaaaaggat cattgctggc ggctataatg gagcagtcag tggagatgtc cactgcatag
    44581 atgaagggtg ttacgtcgtg gatggacact gcttgcgaac gatccatgca gagatgaatg
    44641 cactcctaca gtgtgcaaaa cttggtatcc cgacggaagg ttcagaaatc tatgtcacac
    44701 attttccatg tttggcctgt acaaaggctt tgttgcaagc tggtgtgaaa gggatcaatt
    44761 atctccatga ctatcgaaat gatccttatg cccaagcgtt gatcgaacaa ttaggtgtat
    44821 ctgtacacca agttgcttta gactcacagc atttttcaaa acttcaaaat gaattaacag
    44881 gaaaacatgt ctagcgtttt agaaaggcat gttcgaaatc ggttgatttt tccggcaatt
    44941 acgtcgatga ttatctgttt gttgtattac actgacaatt ggggttatcg tttgcttctt
    45001 gccggaattt ttttatggtt ttcgctaaaa gaaggacgtt ttatcgcgta cttgtgtatt
    45061 ttgtgtagca taacggtatc catttcttat aggctacaag agtattcatt tttagaggaa
    45121 aaaacaacat ctgcgcaaat tactgtattt acagatacga ttcgtgcaaa tggtaatttt
    45181 ttgacaatgg aaggaaggtt atcagagaat aaacaaaagc tccagctttc ttatcaagta
    45241 aacacagaag cagaattgaa aacatggctt aacttccgag gaaagggaat agaattgact
    45301 gctgaaggcg agttcatctc tccagcaaaa aagcggaatc tttataattt tgaccaagaa
    45361 gcttacttca ggaaccatag aatttctgga cggttccaaa ttcaaaagat tgaacagatc
    45421 accatgcaaa atcactggcg aaactggctt cagagaaaaa gaggatcttt tatctccttt
    45481 gtccaatctg aatttccgca aaaaacaagt gtatatatta attctttatt atggggctat
    45541 aaagatgcag gattcagaga accagaagaa atttttaggg agagtggttt gctgcatctg
    45601 ttcagtctat cgggtctaca catccaattt tatttagggt ggctgtatta tttgtttcga
    45661 cgtatcggat ggccactaca cgtcagtatt attccgttga gtctactaac tatctgttat
    45721 gtttctattg caggaagttc tatttctgtt ttgcgtgcta gtttgctgtt tttattgcga
    45781 ttgctagtca aattgctgaa taagcattat tccaccatgg acttatttgc agttgtcttt
    45841 tggcttcttt tactatttga tcctcgattt ctttttcatg cgggtggaca gcttagtttt
    45901 ttcatgagtt ttttgtttat cctgatttct tttgatggag attggttgaa aaaaacggcc
    45961 tctcacgtcc tgtttactat gatcacgatg ccgttgattg tatggcattt ttatgagtgg
    46021 cctattttag gtagtctttt tacattactg attgcaccgg tattcaagtt tctttttctt
    46081 cctggtgtgt tatttctcac actcttcaat cgctggctgc cggaaacttt acttttgctg
    46141 atagaagagg gattaatctt atttgagcga ataatcgatt tttcttcagg gtcgtctctc
    46201 attataggac gtttgcccct tgtgctatct gggatgtata ttttcggatt actgatttgt
    46261 atggataggt tgaaagaaca acctgtgaaa cacttgtttt atgttggtct tttttctttt
    46321 atttttttga ctttgccatt tttacgcttt tcttcaacga tcgcttttat cgatgtcggt
    46381 caaggagaca gtatcttttt gcaaagtcct tttcgaaaag aaacgatttt gatcgatact
    46441 ggaggtcagt tacactttga aagagaaaag tgggcgcaag gtatgatacg tcctcctgct
    46501 gaaagaaata tcgttccata tctaaaaggt caggggataa gtgtaatcga taaactcatc
    46561 ttgacacacg acgatacgga tcatgtggga gaattaccca cgttatctca gcattttact
    46621 atcaaaaaaa tttatatcgg ttggggcgct ggacgaaatg agccattaca aaggcattta
    46681 tctgaagctc aaaaaaatgg tactgagatc attgaaatca aacatgggga caggatcagc
    46741 ggttattatg atctttatgt attgactcct tttgaaaagg gagagggaag aaatgaagat
    46801 tcgattggtc tatggatgga atataacaat aggcgctttt tatttttagg agatttgaat
    46861 caagcaatgg aaaaacaatt gcttttgatt tatcctaatc tgaaagccga tgtagtcaaa
    46921 ttaggtcatc acggtagccg tacgtcaagt aacacagatt ttctttccca tattgaagca
    46981 aaacatggga ttatatcctg cggcgtaaat aatcgttatg gtcacccgca cagcgaagta
    47041 ttggagacac tagaagaaaa tcagataaaa acatggcgaa cggatcaaca aggaatgatc
    47101 acctatcgct ggcatccagt ttttcatcct catgggctag tggaaacaat gatagactag
    47161 taattctcat ctgctcatgg taggataatt tttgaaagtg gtgagtaatt tgagtataca
    47221 agcagagtta caaaaaatac gtaaagaaaa acttgcatct tgttacttga ttttaggaac
    47281 agaaaagttt ctccaagatc aagttcggac agaaattgtc aaaaaaatcc aattagaggg
    47341 cgaagatgac ttaaattttt taagttttga catggaaaat gcaagtttag atgaggtagt
    47401 agctgaagca gagacgttgc cgtttttcgg agatcaacgg ttagtattcg tagagaatcc
    47461 ttatttttta acaggtgaaa aagtaaacaa tggaatcgaa caaaatactg atttattgac
    47521 ggcttatttg aaagaaccat tagaatcgac tgtattagta ttctttgcgc catatgaaaa
    47581 gttggatgaa cggaaaaaag taacgaaaca attgaaaaaa acagcaatta tcatcaatgt
    47641 ccaacagttg aatgaaaaag aagtacgtca atatctgatg aataccttag agaattcctc
    47701 aatcaaaatg gaacgaagtg caattgattt attcttgagg ttgaccgact tagatttatc
    47761 caaaatgatg agagagttac agaaattggt cctttatgga caaaatcaac agcaaatcac
    47821 ggtaagagaa gtagaagaat tagttcctaa aacgttagaa cataatattt ttgacatgac
    47881 ccaatatatt ttaaaaggga agacggaaca agctttgcgt ttatacgaag atttagttat
    47941 gcaaggggaa gaaacaatca aaattaatgc gattttgctt tctcaattac gtttattttt
    48001 acagacaaaa tttcttgtaa agattggtta tcagcaggca aatattgctg aaacattgaa
    48061 aatccatcca tatcgtgtaa aacttgccat gcaggaagta aaaaaattcg atgaacattt
    48121 gctggtacag ttgtttgatc aattagttga gatggattat caaatcaaaa cgggacaaat
    48181 cgaaaaagaa ttaagttttc aactattcgt tttgcgcaca gggcagttgt taagaaatcg
    48241 ataagaagaa agacgagggc aaagcatgcg ggaaggtcgt ttgtttttgt cctttttttg
    48301 acaaataaaa aaatcggccg aagccgattc ttttatttag cgattttttt gcttaaacga
    48361 gatttgtcgc ggttagcttt gtttttgtgg attagacctt ttgattcagc catatcaata
    48421 gctttaacag cttctttata taacgcatct acgttgtcag cacctgaagc tacagcatct
    48481 tcaaattttt tgattgcagt acgcatagcg cttgtttgag atgaattttt cacattagcg
    48541 ttttcgcttg tacgaacacg tttgattgca gattcaatgt ttggcattag tttcacctcc
    48601 gataacttaa gttcttacgc gtgttaccgc ataattcaac attcattatt atacctaaag
    48661 gcagcgtgct ttgcaatatg aacatgacaa gtttttttcc ttaacagtct tttattagga
    48721 ttttttttca gtaaaaacgg atagtacaag ctgaaaaaaa tcaaaaagac gctattgtgg
    48781 gaggcaatag cgtcaaacca aactagattt ttatttatct atttaaacaa agtttgaatg
    48841 ggaatgtttg gtactaagtt attatataac aaagagaacc gtttgcaaag ttttttttga
    48901 aaagggatac gattccctgt tgttctttgt ttttctatta agaaactgca gttattttat
    48961 aaccagtatc ctttgatcag taaaggctat tctggtgtac cgattatttt aatgtattca
    49021 tcgatatttt ttatcaacat tttttttatg accaactggt tccgacggtt ccatttgcca
    49081 cttacttcca gcacatattt atttaggggc aaacgtaaga tatattttgc caaatagcga
    49141 tctttaagca ggccattgat cacacggtcc tcaagctgca agttgatccc agtcagcatc
    49201 attggctgtt cttgtaaaac gtacgtatca attaaaagac cttcaaaagt ttccacaagc
    49261 gtcttccttt cttttcaaag taacctgaaa acaggcacta attcttccat tttgatattc
    49321 gttgaagtgg atgcgatcat tctttctttt gtccactgta atctagtata acaaaaaaga
    49381 gcagaagagc caaaaagaaa aaagagcatc gaattctata ggaagtctca ttggcacggc
    49441 ctaaattatt acaaaacatt gattaaaaaa agcccctgca tcgcaggagc atcccctata
    49501 tcgttttaat aggtcaatca aaaagcagta tcaaacacat tttgtatcaa atcaggaaat
    49561 aatagataag ctaagcccag aatcaaaagt accgctagaa gaaaccagcc gattgttcct
    49621 atgaaatact ttaatttttc gaacattgta tcacctcgtt gtcagtatat cacggatcag
    49681 taaattgggg gtgttaagaa tctcctaaaa tagacaaaat ttgttctatt ttcctaaagc
    49741 aaatacttgt aagatacagt aagtgatacc agaagcaatg accggtccgg cggcgattcc
    49801 tcttaagaag acaacaccta aaatcgtgcc gaaaacaagt gcaacagtga tttgtggatc
    49861 agaagcaatc aatcctacac ccttggaaga taagacagcc actagcccac cgcaaaaaac
    49921 agctacccag ccaatagggg atttaaaggc ttctaataga tcacgtagac cgatttctcc
    49981 tgttgcgata gggattagaa tagccgctgt gatgatcgtc accccaatat tgattccttt
    50041 gccttgaagc caagggaaaa aggaacggga ggctggtatg agcttcataa tcaaaacaaa
    50101 agctgccgct atcatcagac tttgattttt agctaaaatt gctacaagta aaataattcc
    50161 taaaaaaagc caactttcca tgaaatatat tcctcacttt cttcgaaaca atcataacat
    50221 gtttttagaa agttacaaaa gtaggaattc atccttcaag acctattcat aagctgtttt
    50281 tttcataaaa taaacaaaat cataaaaaaa cactttgctt atttgacaga agacagccgc
    50341 gctttgtata gtggacaaga cttacatttt tttgaagaat cagaaagatc aggtaaaggt
    50401 cttagtaaac gcaagccatt cagaataacc aatattgtgc ttccttcgtg tcctacaact
    50461 ccaagaggta gatttaaaaa ttgcaggaag ttagaagcaa tcaacaagag aataacaaga
    50521 atcgaaaaaa taatattttg tttgatgatc cgccgcattt ttaaagatag ccgatgactg
    50581 tagacaaatt tatttaagtc gcttttcatt aagacgatgt ctgcgatatc catagcggca
    50641 tctgtccctt gccccatagc gacacctaaa gaagcggctg ctaaagcagg cgcatcattg
    50701 actccatcac caaccatcgc atttacttgg taaagttcat tctctttttt gactagttgt
    50761 gttttttctt ccggagtaca gcttgcatag taatgttcaa tccctacttg ttcagcaatg
    50821 gcctttgctg tgccagaatg gtcgccggtt atcatacttg tatggatgtt ttgggattta
    50881 aagtaggaaa ttacttgttg ggtatttgct tttggaatat ctagcagacc taaaacagca
    50941 attaactgct gatctttaga aagataaatc acggttttgc cttgattttc caaacgttcg
    51001 atcatttccg caatctcttt gctgattatc atcgtctcag gatcatatgc gtgcttgcca
    51061 actttccatt gcgcacctaa ataggtagtt tgtaatccaa aaccagtaat ttcttctatt
    51121 ggtaagtatt ggatttcttc aggtattgtg caatcgaaat attgcaaaat cgcatgagca
    51181 agtggatgcg tcgttttttg ttccatagca acaagaagtt gttgtgccaa atccttttca
    51241 tcaaagaaaa agctgtcagt tacaactggt tttcctttag tgagcgttcc tgttttatca
    51301 aaggcaatcg cttttaattc agaaagcttt tctaaatgga taccgccttt gattaaaatc
    51361 ccattttttg cagaatttga aagagcagct agagaagctg gtgtagcaga tgcgacaagc
    51421 gcacaaggag aagccacaac taataatacc attcctcgat aaaagctttc atcccaactc
    51481 caacctagga aaaagtgggg gagaaggatc attagaggaa cagcaagcaa aatcaatttt
    51541 acataattat tttcgattcg ttcgataaat gaagctgttt gagttggcgt attctgcgct
    51601 tcttctacta attggataat cttagcaaag acagtttcgg aactcgtttt tgttactcga
    51661 atcgtgatgg gatttccttg attcagcgtt cctgcataca tctcatcgcc taaatatttt
    51721 tctacaggca cagattcacc gcttaatgca gactcatcga tcgttgcctg tgtgctttct
    51781 aaaaagccat ctatcggaac agctgctcct ttagcgacaa ataccaagtt atccaccttt
    51841 agttgagaaa catctacttc ttgcatttgt ccattttctt ttaataattg ggctttttgt
    51901 ggttgaagat tcatcaaagc agtaatttct ttttgacttt tattagttgt gtattcctct
    51961 aatgcaccgc ttaaacaaaa gatgaatgtc aacattgctc cttcaaagta attaccgatc
    52021 aaacaggcac caatagcagc taaagccatc aataaatcca cattcagtgt ccgatcattc
    52081 cacaattctt tcaagccttc cgatgtttgt ttatatccac cgatgataat ggcactgata
    52141 taaaaaagtg gggtgatggt aagagagaat cggtcgaaga taaaaccgaa gatcataaat
    52201 aaaaggcagc cgattgttgc tgcaaaagct tttttctgat tagtcatcgt tattagacct
    52261 ccttgtcaaa acaaggatag cataataaaa atgtaattga taataataac agctaaatga
    52321 gaacgataat ggttatcatt tggtgattaa gcttgatgtt gtttttatta tttataatga
    52381 ttattattaa agaaaataaa aaaccagaac atttctcaaa taagagaagt gttctggttt
    52441 tttctacatt gcaataaacc aataaccaat caaaatgata ccaaggataa tacgatacca
    52501 gccaaaagcg gtaaagtcgt ttttcttcaa atagcttagt aagaatttga tagctaagac
    52561 ggaaaccaca aaagatacga atgttcctac aagaagaaca acagtttctt ccattttgaa
    52621 tgaattccct tcagctaaat atttgacgat cttcaagccg cttgcgccaa acatgacagg
    52681 aatccctaag aaaaatgaaa actctgtagc gacaaaacgc gaagcaccaa tcaagataga
    52741 tcctaggatc gttgcgccag aacgggatgt tccgggaaca agtgccaaga cttggaataa
    52801 cccaacaaga agagctgctt ggtacgtaaa gtcattcaga gaagtccaac gaggtgtttt
    52861 gtttttgttg cgtttttcga caataataaa ggcaataccg taaacgatca aaacaatggc
    52921 aactggtaag aacttgtgga aatttgcttc taaccaatca tccaaaggca aaccaatgat
    52981 gatggctggt atgcaagcaa cgatcacttt aaaccaaagt gtccacgtat cttttttttc
    53041 taccgttgat ttacttggag aaaatgggtt taacttgtga aaataaagaa cgacgacagc
    53101 caagatcgcc cctaattgga taacgacatt gaacatcgac ataaattgtg aactggcatc
    53161 cagtttgatg aattcatctg ctaggatcaa atgaccagta ctactgatgg gcagccattc
    53221 cgttattcct tcaataatac cgagaatcac tgctttgata atatttgcaa aaaacataaa
    53281 ttccttcctt cccaattaag atacatctta tagtataccg ttattttttg agaaacccaa
    53341 tctgtttttt aatattaaga aaaacttgag aaataaagca gataagtaca cgaagagaaa
    53401 aaagaagaca aagccctcgt tcagactttg ccttttatga ttctctggta aaaattaaaa
    53461 tatccccatt atagaaacga gtcgcgacta tgtgttttcc cgttatcgat ataagacgta
    53521 tcattgatgc cgtggataga aaatcgaccg tttgcataag tgacctttgt tacgctgcca
    53581 tttaaaagcc cagcacgaac aggctgttta ggatcgatca gattaagcaa aaaggcgatc
    53641 gtcaaaccat gagatacgac taaaacattt ccaccaccat ttttttcgca gtgatgggcg
    53701 atatcttcaa atcctgtcca tacacggtct cgcaatgttt cataagtttc cgcccaccca
    53761 gcggtatcta agttgtatac agcattagca atttgttcaa aagaaacttc tgtggtaaac
    53821 atttcatcat atgttttaaa attcaataca cgagggatca caccccacat ttccatgtca
    53881 tatccacctt caagagaccc gaaacaccat tctctaatcc ttttttcaat aaaataagga
    53941 atttcttttc ccttagaatg ttctcctaga ataatacggg cagtttcgat tgcacgacca
    54001 ctgtcactag aataagcaaa tgaaaagtcg acatttttta acccgcgacc taaataatga
    54061 atgccttctt gtccttgctt tgtgaggggt gtatcacacc agccttgtac tcgttcaatt
    54121 gtattgaaca tcgtttttcc gtgtcgtacg atataaagtg tagtttctgt cattttattc
    54181 tcctcctaag tcgttttaac gattgaaaaa aggatttgtc cttttttcct gttcaatcgt
    54241 cgttgcatcg ccatgtcctg gatagactgc aaattcatca ggtaatacaa acagctgggt
    54301 ccgaatacta tgaagtaatt gttctaaatt ccctgtatac agatcggttc taccgatact
    54361 tcctctaaac agggcgtcgc cagaaacgac aaaatcatca aaaataaagc tgacgcttcc
    54421 tatagaatgc cctggggtag ggacgacgcg aaaagacatg tttcctaaag tataagtttt
    54481 catttcaaat tcatattctg caggcgagac aataacatca gcaatatcat catgtctacc
    54541 gagtccagaa agattcaaaa tcggatcacc tagccatttt tgctctagtg ggctgacata
    54601 aactgggatt tgataatacg cgcgtaaagg ttccactgca ccgatatgat cgtagtgagt
    54661 atgggtaagc aaaatcgcta ccggctgttg gtttgttttt ttgatttctt gtttgattcg
    54721 ttccgcatct tctccagggt caatgatcaa aagtgcttct tcgttgtaga ccaaataaca
    54781 gttttcttca atcattcctg tttttaatct ttcgatatgc atgtgcattc ctccttgata
    54841 gccaaaactt ctttcatcca ttagtataac gcattcattg ctaggaaaca aaaacaggta
    54901 cttatttctc tttacttatc tgaattatca gactatatga aaagtatttg gatattctaa
    54961 agagaaggaa agtaagtttt catagcattt taatatgtcc ttgttacatt agattcatcc
    55021 aaaaatccaa attctatatc ctatatccct gcctaatcag cagggtgttt ttttatgttt
    55081 ggaaagagag ctctttttgc taaactaggt tttttcaggt aatcttagag agaaagaggt
    55141 ggtggaaatg atcaaacagt caaaaatatc tgtgcggcac ttagtagaat ttattttgcg
    55201 acgtggaagt atcgacaatc gtaaaaaaag taaccatact gcattagaag gagcgagaat
    55261 ccaccgcaag ctccaaaaag atgcgggaga aaactatgaa aaagaagtct ttttaaaaac
    55321 aacagttcaa ttagatgaat attacctgat cgttgaaggc cgtgcagacg gtattttcaa
    55381 aagagacggt atttattata tagatgaaat caaaacctcc gaaccacgat ttgaagattt
    55441 agaaccagaa caagtggaac ttttctttca tcaagcaagg gtgtatgcct atatctatag
    55501 tcaagaacat gatttacaag aaataaatct gcaattgact tacttccaga cggcagaaga
    55561 agtgatcacg agaaaggttg aacatcagac aagagagcag ttagaaactt tttttaaaaa
    55621 gctgactgaa gattataaag aatggcttgt ttttcaagaa aactggcgca ctgtacgcaa
    55681 tgcctctttg atggctttga aattccccca tgatgagtat aggaaaggtc agcgtgaact
    55741 agcggtagct gcttataaaa cgatccgtac gaaacagaaa ttgtttgtag aagcacctac
    55801 cggaacagga aaaacaatct ctacgttatt ccccgctttg aaagctgtag gggaagaaga
    55861 gggagaaaag atcttttatc taacggctaa aacaataact agacaagtag ctgaagatgc
    55921 tatgacagca ttaaaagata caggagctga agtaaaaagt gtcactttga cggcgaaaga
    55981 caagatctgc tttttagatg agacgacctg taatccagat cagtgcccat atgccaatgg
    56041 ttattacaat cggattaatg aaggtttatg ggatcttttg aatcatgaga atcagatcac
    56101 tcgtgaagtc atcgaaactt atgcaagaaa gcatacactt tgtcctttcg aactatcatt
    56161 agatgtcagt atctggtgtg acgtaatcat tggggattac aattatttat ttgatccaac
    56221 tgtttattta agacgttttt ttgaagatga aaaaaacgag gactatctgt ttttgattga
    56281 cgaagcacat aatttggtga atcgttcccg agagatgtat tcggcagaac tatcttatga
    56341 aaaaacgaaa cgaagtaagg aagctatacc aaaggaattc aaaaaacttc atcgccgttt
    56401 caacaaacta ttaaaagaat ttgattcgat ccgagaaata gcaaaagaag atcattggga
    56461 ttatcatcat caaaaagcac cggctgaatc tttagtaaag gcaggttatc aattaagcga
    56521 aaaaattaaa gaatggctgg cagaatttcc tgagcaccca tcacaagaac aattgcttcc
    56581 ttattatttt gatttgcttc attttttgaa ggtcagtgaa ttttatgatg atcactacga
    56641 aacaacagtc gaaaaaacgt atcgcgatct gatagtaaaa gagttttgta ttgatccaag
    56701 cttgtttctt gagcagtcgt tggataaagg aaaaagcagt attctttttt ctgctagttt
    56761 ttcaccactc tcttattatc aggaaacact ggggggacaa aaaagtctgg cttacaaact
    56821 gccgagtcct ttcccagaag gaaaccagca agttttcatc gcaaattacc tagagacgac
    56881 ttatcgaaaa agggaacaca gtctggcaaa attagtagag acgattcatg cttttgctga
    56941 tggaaaggtc gggaattatt tcgttttctt tccttcttat caatatttag atcttgcggt
    57001 ggaagcattc agacagcaat atcccgacag caatgtgcta atccaagaaa cggacatgaa
    57061 tgaggaagaa cgcgaacgat ttttaacaaa atttcaaaca aatcccgctg aaacattgat
    57121 tggattttgc gtacttggcg ggattttttc agaaggaatc gatttgagag gggaccgatt
    57181 gatcggcagt atgatcgtag gtgtaggttt gccgcagatg aatcatgagc aggaactgat
    57241 caaatcatat tatgatgaga aggaacacct tggatttgct tacgcttatc agcttcctgg
    57301 aatgaacaaa gtcttgcaag ctggtggtcg agtgattcgt ggcatggcgg atcaaggaat
    57361 cgttgtattg gcagatcaac gattttctag tttttcttat cgacgtttat tcccacaaca
    57421 ttggcaaaca gcaagagaag tacgaagtgt tggggaattg gaagaaggaa tacagcgttt
    57481 ttggttatca aaagaagcag taaatcaaaa aaacgaggaa tgacagacgt cagcctcgtt
    57541 ttttgattaa cgatagttag tgaattgcaa ctcgattggt aagtcaagtt tacgtaataa
    57601 agcaatcaca gcttgtagat catcacggtt cttacctgtc actctaatct gatcttcttg
    57661 gatttgtgct tttactttca gtttttcatt tttgatagct gtagtgattt tcttcgcgtt
    57721 ttcacgatcg attccgttga ccaaatcggc agtttgtcga gctttgccac ctagagcgtg
    57781 ttctgattcg gaaaaatgga tatttttgat tggcacattt cttttgatca gcttaccaaa
    57841 taatacatct ttgatctgtt cgattttgaa atcatcatcg ctcaatacaa ctagattgct
    57901 gttctctaat ttgatttcta ctgtagaatc cttgaagtca aagcgattgg acaattcttt
    57961 tgttgtttgc tgaatcgcat tttttacttc ttctgtattg acttctgata caatgtcgaa
    58021 gctagcatct tttgccatag gaaccctcct gatatacata taaatattta ccatacatct
    58081 atcttatcat aggattaggg cagattctta cctgtttgct aaaattcttc tcatttgagt
    58141 tcgaagtatt ttattttaat agataaactg ttattcttac atttggaata ccaaagtagg
    58201 ggagaggtgc ttgtgagtaa aattatgact gcgtatcata aaaatgaaag attaaagaaa
    58261 atagtggtta ttttgataac cggattgacc gctgcggtcg ctttaaatta ttttttgatt
    58321 ccagccaatg tcttttctgc agggatgaat gggatcgctc aaatcatttc ctcgctttta
    58381 tatgaatggt ttcatatcaa gatagacaca ggaacattta tttttctttt gaatatccct
    58441 gtgtttgtat tagggtttct caaagtagga aaacgagcaa cgatccttag ttttgtgaat
    58501 gttgtatgtg tatcggtgat gacgatgctg cttccagtcg gacagatcac tgataatatt
    58561 ttgatgaatg ccctagtagg cggtgtttta ttaggtcttg gcgtaggatt atctttaaaa
    58621 atgggcttta caactggtgg gatggatatc atctctcttg tactttcaca aacaactgga
    58681 aaaacagtcg gaaactacat gctgattcta aatggtatca ttgtagtcat cgcaggcttc
    58741 ttctttaact gggaaagtgc cttgtatacg attatttcca tttatgcaat gactcaagta
    58801 attgatgcca tccacacgag tcatcaaaaa gtaacagcaa tgatcgttac cgtcaagcca
    58861 gaagaggtaa cagaagaact agcaaaacgg atggtacgtg gaatgacatt actgccgtct
    58921 gtcggtggct attcaaaaaa acaagggaac atgatcatga tggtcatcac ccgctacgaa
    58981 atgtatgatc ttgatcagat cgttcatgaa atcgacgacg atgcatttat caatatttta
    59041 ccaactcatt cagtatttgg ccggtttgca aatgaaaacg aacaaaaaat gtatcgaaca
    59101 actggcgtat tgccagaaat aaaaaatcgt tcacaaaaaa aatgaggaat caggtttatt
    59161 ttagaataaa tttaatctat tacatctaat aagaacattt ttataaattt aaacgagaat
    59221 cttacttcta aattctcatt tacaagcagc taaaaaaaga gtatgataaa taaaaatcgt
    59281 gttaaggagt gtcgtacgat gagcgaagca aaccaagaac ggtctggaca agaaatagaa
    59341 ctaatcaaag aacgtattct tgctgccttg gaaatggtga ttgatcctga attaggaatc
    59401 gacatcgtca atttaggctt gatttatgat atagaattca atcctgaaaa tggagaaaca
    59461 gtcattaaga tgactctaac aactatgggc tgtccattag cagatatttt aacagaatct
    59521 atccatgacg cattaaaaga agtgccagaa gtaacgaaag cagaagtcaa actagtctgg
    59581 tatccagcat ggacgacaga taagatgagc cgttatgcac ggattgcgtt ggggatacga
    59641 tagaaatctt ggctgactag ctatgagaag caaataggaa aaacaaaaaa gccttttatc
    59701 ctttctagaa gaaaagagat aaaaggtttc tttgtttata aaattttgtc tgctatatta
    59761 taagttaatt aaataaatgt gttctattga taaaggacat tcaaatccct ttccttttgg
    59821 aatccttctt ttttacatca gtttgatttt cgtatagtat tctttctcat cttcacgata
    59881 aatcgcagcc ccattttttt gttgtgcttt aagactgcca agattttttt tatttacaga
    59941 caaaagtgcc tcatcaatgc cgattttttt tgcctcttgt agtactaatg ctaatccttg
    60001 tgtggcatat ccttttttac gataattagg ggagatgccg taaccaatat ggccagcgcc
    60061 gtttcttaat gtttcgttca gtttatggcg caaattaaaa attcctacat actcatgttc
    60121 atcactttct aaaataaaga cggttgcggg aacgtaactc tcaggaagat cgattcctaa
    60181 agacgttttt tcgcattttt ttacataatc taaaaattca gcaaatgtat agccataagc
    60241 attgttgata aatccactct catttggtcc aaagctagtt tgtagctgat aagctttctt
    60301 taaatctgct tcccatagtt tgatcagttt catcgtattc acctctttaa gtaaccttat
    60361 tcatttgttt tctactatag cactattgtt gtaaatagcc atgcctattt ttatttattg
    60421 tgtcatatcg tattaagaat catcgaacaa tacaaatatg aattacaata aaaaaattat
    60481 ttgaagttcg ttcattcgtt acttatgatc tctagaagaa agaaaacgtg aattacttca
    60541 gcgtctagaa ttccagaagg atagtaatca acagaagaaa taatcaatat ccaaatgaaa
    60601 gaagatagct gaatcgagaa aaagaggaaa aaagaaatga agaaaaaaat aaaatagtta
    60661 ctaatcccag agtcgttcgt ttaacattga aatcgatcat atggataaaa cagatttttt
    60721 caccaaccct caatagatga tggagttgct cggatgaatt atttgtgtag atggcataag
    60781 ggagggcgta cagaaatgaa aaagaacaaa aatatgttct tgacaaaaaa cacatgtaat
    60841 cctaaactaa aagatgtgat gcggctatgg cggaattggc agacgcgcta gcttcaggcg
    60901 ctagtgaggg tgacctcgtg gaagttcgag tcttcttagc cgcataattt gtttttttat
    60961 aaagagaagg tacacctgga gcgatgagaa agaaaataac atattatcta aaagaatata
    61021 ggaaaaattt taaacaacgg aaccagattc aaataaatca aaaaaaattt gtgtgaaggt
    61081 gggacagttt aaaacctaat agattgattc aaatagtaga tttatagatt ctgatacaag
    61141 aaatactggc aaacgatagt taaggaataa agactaaact taaactcaaa aagaggtcat
    61201 gcgaaagaat aaatcgcatg acctcttact atattttgaa tgtgtttaaa cgttcaaata
    61261 atgaatctta gtaccaaccg tttgcttccc agaatgcttt cgccgcttcc caagaaccat
    61321 aacgtgaagt aacatattgt tctgctactc tttcttggtt tgcagcagag tagtcaccat
    61381 ttaagtaaga agaatctaat tggtaacggc cgatgtaacg tccgttcgtt gctgtgtaag
    61441 aaccgcttga ttctttttgt gcgatccatt cttttgcaga gcttgtactt gctggagtag
    61501 cagcagtttc tgttacagca ggagcaggtt gtgtttcagc aacaggcgct gcttgtgttt
    61561 ccgtttgaac cgtttcttgt acaacaggtt gttcagcttg aacaggttca gcttggactg
    61621 gtgcttcttg aacggctgct tgaggttcag cagctgcttg tgcagagcct tctgttggga
    61681 ttgttaattg ttgtcctgag ta
//
LOCUS       DAZUJR010000005        60150 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.005, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000005 DAZUJR010000000
VERSION     DAZUJR010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 60150)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60150)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60150
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.005"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(33..1076)
                     /locus_tag="ACG804_000285"
     CDS             complement(33..1076)
                     /locus_tag="ACG804_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HFS4831248.1"
                     /translation="MKKILVSLLFLVSLVTLVGCSQSQGEKQSEKEKSKIALVLGFGG
                     VDDRSFNQAGWEGLEAWGKEKKLTAKKDFTYIETNNPEDNSTNIDQAIRNGFTTIISL
                     SYLQAEELENAAKDNPKLKFALVDGEITGKKNISSATFKDQESAYLAGLAAAYTTKSD
                     QVGFIGGMEGPVIQRFQSGFEAGVKAGATALNKEITVNVQYAASYDSLDKGKAIAASM
                     YKEGVDILYQAAGSTGAGVFQEAKARNENDYSRKVWVIGVDRDQADEGDYKMENGETG
                     NFTLTSTKKNVGAEVKEFAETSHNDKFPGGKHLTFGLKEEGVDLTKGQLSEEAYQAVS
                     DAKEKIISGDFRL"
     gene            complement(1237..1920)
                     /locus_tag="ACG804_000286"
     CDS             complement(1237..1920)
                     /locus_tag="ACG804_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HFS4831249.1"
                     /translation="MKKIHDTKQLTAYVEKHNLQDYMDSDILAMASLLFFEKEEHLIQ
                     TGKTSDYLYFLVDGTVMVYSYSSDTQNICIDYAKPATPLGEASSLWELSPKSSVKAVT
                     KCICISIPLNQYRTQLQKDVRFLQNICQLLSYRLNSGINLANSLTEPVETRLAKFILT
                     HHENERFSFRLTTCASILNVSYRHLLRTITNFREENIIEKKKNYYLIHDIEALEDLAE
                     NISSPVKAE"
     gene            2115..3044
                     /locus_tag="ACG804_000287"
     CDS             2115..3044
                     /locus_tag="ACG804_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate/phosphite/phosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HFS4831250.1"
                     /translation="MQFKQLAKGFIGVMLLTTLAACGSGNTSSSSEKESKEKLVVQFV
                     PTNNDGSMEAKAKPFAKYLSKKLDREVEVTLATDYSTIVEAMSSGQVDVGIMPPAAYV
                     QAKDAGAADAILTSQLGDYDQETGLPLKDKLTNTFKGEVLVRADSGLNKLTDLKGKNI
                     ATLSPNSASGYIYPVAELKDAGIDPTADTKMTTVNDIPSEITAVLNKQMDAAFVFEGA
                     RNVFASNFPDNDLFKDLKVLYLTKGDIPNDAIAVQPDMSKDLKAKIKETFLNMKDDKD
                     GKEAMALWGHQGYEEAADSAYDTIRDYTKKAAE"
     gene            3105..3896
                     /gene="phnC"
                     /locus_tag="ACG804_000288"
     CDS             3105..3896
                     /gene="phnC"
                     /locus_tag="ACG804_000288"
                     /EC_number="7.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015416 - ABC-type phosphonate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015716 - organic phosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter ATP-binding protein"
                     /protein_id="HFS4831251.1"
                     /translation="MIIFDNVSKVYPNGVVGLKDIDLTIEDGEFVSIIGLSGAGKSTL
                     LRSINRLAETTKGDIRINGTSITKANKKELRQIRRQIGLISQSFNLVKRSTVQKNVLS
                     GRLGYYSTWKSILGLFTKEDYQQTKEALEKVGLSDKLQTRSDELSGGQQQRVSIARAL
                     VQQAPIILADEPVASLDPITTQKVMMDLKNINQTMDKTVIVNLHSVPLAREFSTRVLA
                     LKAAQVVFDGRPDDLTDERLEQIYGNAIFEEKAGEIDELERNRSL"
     gene            3868..4647
                     /gene="phnE"
                     /locus_tag="ACG804_000289"
     CDS             3868..4647
                     /gene="phnE"
                     /locus_tag="ACG804_000289"
                     /EC_number="7.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015416 - ABC-type phosphonate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015716 - organic phosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HFS4831252.1"
                     /translation="MSLKETVHFKWYKHLLILLFLIVCFQGSAWITSADFSQVFQNSN
                     QMTVFLSRFIHPDFSYLPKLVEPMVKTLQMSLLGTVIGLILAIPVSFLATTVVTENRL
                     LSTIFRFLLGLVRTIPTLLLAALFVAVFGIGEATGVLTIAVFTFGMVSQLMFQAIETI
                     DFGPIEAAAAVGANKMQIAIWSIAPQVLSQFASYAFYAFEVNVRASTVLGYVGAGGIG
                     VILNSSLALLNYERVSIIILTILVTVAIVDKLSERVRRSLL"
     gene            4644..5426
                     /gene="phnE"
                     /locus_tag="ACG804_000290"
     CDS             4644..5426
                     /gene="phnE"
                     /locus_tag="ACG804_000290"
                     /EC_number="7.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005233297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015416 - ABC-type phosphonate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015716 - organic phosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HFS4831253.1"
                     /translation="MMLREMNRRTLLSLVALVILVILSAATLDYSGLSTFSPSMGMDV
                     LRGLGQPDWQFLYDGSGEDLISLLLLTIGIACLGTMIATVLAIPITLISAVNLWQAHP
                     WVTKIGKLICNVLRAFPELVFAIIFVKVVGPGPFAGVMAIGVHQIGMLGKLFTEEMEA
                     MDERLVEEMHAVGANFWQTIFFVRIPYLMPIYCSLALNHFEIAVRSAATLGLVGAGGI
                     GAPLIFAIQTRSWSKVSIILIGVVVTVFILDQITGIIRKRLR"
     gene            5429..6232
                     /locus_tag="ACG804_000291"
     CDS             5429..6232
                     /locus_tag="ACG804_000291"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFS4831254.1"
                     /translation="MNILHISDIHFRREYEACEEGYKGMLATMQNPLIPLEQCIHHLL
                     QQTPLDLVIISGDLTEDGEIDDYRYLKTWLENALGETTILVTLGNHDIKEHFWVGWCD
                     EAASSAPYNQIVKYPEFTVISFDNSSYGYADGIVDDQQFQWLKKALEQEKDQPIFLVT
                     HHHLLSHQSSIPKWPGTERFLKLIAPYDIRCILNGHTHHTFTDEINGIPYFTVSSMSF
                     VGEDEGDGFVRFEERHGYNLYHLDQGRIVRQTTENFIPGNILKTLQMKD"
     gene            6316..7863
                     /locus_tag="ACG804_000292"
     CDS             6316..7863
                     /locus_tag="ACG804_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-sugar
                     hydrolase/5'-nucleotidase"
                     /protein_id="HFS4831255.1"
                     /translation="MNITFLETSDMHGYVSPTDYSGRTDLALGTAKVSSKLKELRAKA
                     DGPVITIENGDFIQGSPLSYYLAKEYGSAKELTDLINQMSYDVQVLGNHEFNYGVDYL
                     EEAIKNYQAPILGANMVNKNDQPYFGNAYKIIEKVGVKIAILGLTTQYIPHWEKPETL
                     AGITFKSIVETAKEYVPLLRKQADLVIVSYHGGFEKDLLTGEDTEALTGENEGYELLQ
                     QVEGIDALFTGHQHRKIAETVHGVPVVQPGYRGEFIGEIRLTVEKKEGQVVVTDHQVA
                     LHSVEKSEPDPEILAAIVPVEEKLEKWLDQPLGKVNGNMRINDPMQARLEEHPYVEFI
                     NRVQLFASGSEISGTALFNNEGKGFGETITMRDVITNYIYPNTLAVIQINGADLRAAL
                     EQTANYLAVENNQIVFNPAFIQPKPQYYNYDMYEGIQYTIDMKQPVGQRITELRFKGH
                     PVLPQQMLEVVTNQYRAIGGGNYAMFGAEKIVREIQIDMTELIADYLNIHPRIEAKVN
                     HNFQVIL"
     gene            complement(8160..8357)
                     /locus_tag="ACG804_000293"
     CDS             complement(8160..8357)
                     /locus_tag="ACG804_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831256.1"
                     /translation="MVECLKNKKMEANFVKAVISGSIVFQEEYRDMEKDFSKKGIELI
                     DYPRSCPILDKEYPEILTTFF"
     gene            complement(8433..8633)
                     /locus_tag="ACG804_000294"
     CDS             complement(8433..8633)
                     /locus_tag="ACG804_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFS4831257.1"
                     /translation="MIEEEQKNIWDRYYKADPSSKNTKIGESGLGLSIVKELVRLHHG
                     SIEVTSRKNEGTTFLIQFPKEK"
     gene            complement(8753..9940)
                     /locus_tag="ACG804_000295"
                     /pseudo
     CDS             complement(8753..9940)
                     /locus_tag="ACG804_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(9985..11111)
                     /locus_tag="ACG804_000296"
     CDS             complement(join(9985..10883,10883..11111))
                     /locus_tag="ACG804_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFS4831258.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYL
                     PDQSTGLTGKEVAELRKENARLNEELEILKKAGSHILSENLNSLVQFIEKWCKDYTVS
                     LLCRLLEIPRSVYYFYKNKPLTATEIRNNKLKKKISTIFFTNKQRYGATKIHQVLLKE
                     GISVSLKHVQKLMKQLNLRSIVVKKYRPQRSNKPIISKENLLNQDFSTETICEKWAAD
                     ITYIPTKKNGWCYLSSIMDLHTKKIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMIL
                     HTDLGSQYTAREVEQWLKTNKIRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDF
                     EEANRALFSYIEGFYNRNRIHSSIHYLTPQEFEELAKEKMA"
     gene            complement(11515..12297)
                     /locus_tag="ACG804_000297"
     CDS             complement(11515..12297)
                     /locus_tag="ACG804_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831259.1"
                     /translation="MENSSNSAEVNVSTSTSEVVKCSQETTSLPEELLGDWQINNKDA
                     GIEISDSKAVFRIGRSQVESKDYYVDVNNKMLLHVYFSFEYDSVKYIEVSIERTGYSE
                     FISKSVGILTMHTKDGQYISLGVKRVSGENNETEAVTEQTMDERIDSSKSNETEVDTG
                     KTIDERIDSFIETYTAIPPTWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNA
                     VTEQVGKDIPLRLLENGKKDYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(12362..13198)
                     /locus_tag="ACG804_000298"
     CDS             complement(12362..13198)
                     /locus_tag="ACG804_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFS4831260.1"
                     /translation="MRVIKTLNNSLILCLDKQGKEVILMGKGIGFQLKKGDLVPADKI
                     QKVFKLDSLSDALKKDYIKLFEAAPDDLIICVKRIIDYANAKFDFKLNKSLFFTLVDH
                     LKHAIERSQKGIVFQNRLLIEIQKYYPKEFEIGCYAIQLINKKMNVQLPEEEAGNIAF
                     HIVNAQSEQANMEETMLSVRALKDILAMLGYLFPEKKVDKDSMLYLRFVTHLQFFIAR
                     MIKKEELPEKDDFLLASVKQRFPKEYRAALKIKEYVQEEMGASANQDELLYLTLHISR
                     VY"
     gene            complement(13216..14625)
                     /locus_tag="ACG804_000299"
     CDS             complement(13216..14625)
                     /locus_tag="ACG804_000299"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFS4831261.1"
                     /translation="MQYKQLSAFPEKFLWGASISAYQAEGAYQEDGKQPSIIDKYQHT
                     EGVANFEVASDFYHHYKEDIQLFKELGLKAFRFSIAWTRIMDIENNKTNQKGISFYHQ
                     VIDECLNQGIEPIVTMYHFDLPYFLEEQGGWLNRATIDYFVDYVQVLLTEYGDKVNYW
                     LTINEQNTMILHPGAIGLPPSGELPSKKELFQINHHVLLAQARVIHLYHQLNLKGKIG
                     PAINLTAMYQATSSPEDAIAAHNWETLRGWSFLDVAVRGKYNYLFENYLNDRGLYPKI
                     EAEDQAILSSGKPDFIAINYYSTATIAASKNDGSDVSARAGDQQIMLGEEGVYRAAEN
                     PYVDKTPYGWVVDPTGLRLTLRKLYDRYDLPILITENGYGAPDIVEEDRRINDQDRID
                     YLAKHILAIQAALTDGVDVFGYLPWSAIDVVSTHQGFNKRYGFIYVDRTDENLKELKR
                     IKKESFFWYQKVIARNGLA"
     gene            complement(14639..16462)
                     /locus_tag="ACG804_000300"
     CDS             complement(14639..16462)
                     /locus_tag="ACG804_000300"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFS4831262.1"
                     /translation="MDYREVGRNVLQQVGGKENVVSLTHCATRLRFELKDKRKADTKA
                     LEKTLGVISVVDSGGQYQVVIGNEVQTAFKEIQKEVGTSIKKGPSSDNQESIISRLIS
                     VISTTFTPMIPAITGAGMVKAILAVLTLTGVLSDSSQTYIILNTIADAAFYFMPVLLA
                     YGAAIKFDVNPILAITVAGILLHPNISQLFSTGDAVSFLGIPVLAADYAGSVLPIIFT
                     VWIMSYVEPFADRISPSFIKFFTKPMLVFLIMGPLALVVIGPFGTLLNDLIAMGAEWI
                     NGKAAWLIPFLMGGLQPFLVVTGTAWAMTPIATMQLSSTGSEMINGPGMLASNIAQSG
                     ATFAVAAKTKNKELKQLAVSTGITALMGITEPSLYGVTLKLKKPLVASMIGGAIAGLY
                     AGLSGLVRYAFVSPGLAALPAFIGENPMNIVHAIITCVIAFVATFIIAYLIGFDDTSD
                     ESEQTAIAEAVIVENPVKGTVCPISEVNDAVFSKGLLGKGVAIHPEENSIYSPVEGEV
                     ITILESKHAIGLRSKEGIELLIHVGIDTVNLKGEPFEVFVKAGDQVSAGQLLINADFA
                     AIRNAGYDDTVIVVVTNSENYAGISEASGSLKEHEPLMQIS"
     gene            complement(17305..17631)
                     /locus_tag="ACG804_000301"
     CDS             complement(17305..17631)
                     /locus_tag="ACG804_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831263.1"
                     /translation="MNKVNMNKKFIIIVIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKAILDNGSAININIEYYPKKDRIYVEIPYA
                     EVLMLN"
     gene            complement(17677..18039)
                     /locus_tag="ACG804_000302"
     CDS             complement(17677..18039)
                     /locus_tag="ACG804_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HFS4831264.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGADAVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVALAFIPVVFGAVAVIMGYLYRDKDEQMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            complement(18076..18290)
                     /locus_tag="ACG804_000303"
                     /pseudo
     CDS             complement(18076..18290)
                     /locus_tag="ACG804_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            18418..18753
                     /locus_tag="ACG804_000304"
     CDS             18418..18753
                     /locus_tag="ACG804_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4831265.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(18829..20826)
                     /locus_tag="ACG804_000305"
     CDS             complement(18829..20826)
                     /locus_tag="ACG804_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831266.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSFYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELTNTVC
                     ERLRNVGNNSVENALKENRGYFVKQGFTLERASKDIKRLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(20924..21199)
                     /locus_tag="ACG804_000306"
     CDS             complement(20924..21199)
                     /locus_tag="ACG804_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4831267.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            21431..22165
                     /locus_tag="ACG804_000307"
     CDS             21431..22165
                     /locus_tag="ACG804_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4831268.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            22204..23346
                     /locus_tag="ACG804_000308"
     CDS             22204..23346
                     /locus_tag="ACG804_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4831269.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(23441..24832)
                     /gene="sufB"
                     /locus_tag="ACG804_000309"
     CDS             complement(23441..24832)
                     /gene="sufB"
                     /locus_tag="ACG804_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HFS4831270.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(24837..25307)
                     /gene="sufU"
                     /locus_tag="ACG804_000310"
     CDS             complement(24837..25307)
                     /gene="sufU"
                     /locus_tag="ACG804_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HFS4831271.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(25294..26529)
                     /locus_tag="ACG804_000311"
     CDS             complement(25294..26529)
                     /locus_tag="ACG804_000311"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HFS4831272.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(26526..27812)
                     /gene="sufD"
                     /locus_tag="ACG804_000312"
     CDS             complement(26526..27812)
                     /gene="sufD"
                     /locus_tag="ACG804_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HFS4831273.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(27825..28598)
                     /gene="sufC"
                     /locus_tag="ACG804_000313"
     CDS             complement(27825..28598)
                     /gene="sufC"
                     /locus_tag="ACG804_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HFS4831274.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(28795..29643)
                     /locus_tag="ACG804_000314"
     CDS             complement(28795..29643)
                     /locus_tag="ACG804_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFS4831275.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(29667..30353)
                     /locus_tag="ACG804_000315"
     CDS             complement(29667..30353)
                     /locus_tag="ACG804_000315"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HFS4831276.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(30346..31380)
                     /locus_tag="ACG804_000316"
     CDS             complement(30346..31380)
                     /locus_tag="ACG804_000316"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HFS4831277.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     misc_binding    complement(31443..31699)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(31775..32113)
                     /locus_tag="ACG804_000317"
     CDS             complement(31775..32113)
                     /locus_tag="ACG804_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HFS4831278.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(32115..32471)
                     /locus_tag="ACG804_000318"
     CDS             complement(32115..32471)
                     /locus_tag="ACG804_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HFS4831279.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(32477..33664)
                     /locus_tag="ACG804_000319"
     CDS             complement(32477..33664)
                     /locus_tag="ACG804_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFS4831280.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(33855..34700)
                     /locus_tag="ACG804_000320"
     CDS             complement(33855..34700)
                     /locus_tag="ACG804_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFS4831281.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            34934..35899
                     /locus_tag="ACG804_000321"
     CDS             34934..35899
                     /locus_tag="ACG804_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HFS4831282.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            36276..37319
                     /locus_tag="ACG804_000322"
     CDS             36276..37319
                     /locus_tag="ACG804_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HFS4831283.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(37381..37845)
                     /locus_tag="ACG804_000323"
     CDS             complement(37381..37845)
                     /locus_tag="ACG804_000323"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HFS4831284.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            38091..39038
                     /locus_tag="ACG804_000324"
     CDS             38091..39038
                     /locus_tag="ACG804_000324"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFS4831285.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(39249..41321)
                     /locus_tag="ACG804_000325"
     CDS             complement(39249..41321)
                     /locus_tag="ACG804_000325"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_function: GO:0098847 - sequence-specific single
                     stranded DNA binding [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0051304 - chromosome separation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFS4831286.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(41254..41631)
                     /locus_tag="ACG804_000326"
     CDS             complement(41254..41631)
                     /locus_tag="ACG804_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HFS4831287.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(41760..42320)
                     /locus_tag="ACG804_000327"
     CDS             complement(41760..42320)
                     /locus_tag="ACG804_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFS4831288.1"
                     /translation="MKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDIKAPSLY
                     NHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSNQAVYEL
                     LISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYLSLRFLG
                     YFTKEPTIDPEDSYFWMINNFIATLP"
     gene            42470..43762
                     /locus_tag="ACG804_000328"
     CDS             42470..43762
                     /locus_tag="ACG804_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HFS4831289.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(43822..44940)
                     /locus_tag="ACG804_000329"
     CDS             complement(43822..44940)
                     /locus_tag="ACG804_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HFS4831290.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(44954..46375)
                     /gene="arcD"
                     /locus_tag="ACG804_000330"
     CDS             complement(44954..46375)
                     /gene="arcD"
                     /locus_tag="ACG804_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0043858 - arginine:ornithine antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006527 - arginine catabolic process
                     [Evidence IEA];
                     GO_process: GO:1903826 - L-arginine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HFS4831291.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(46621..47742)
                     /gene="mnmA"
                     /locus_tag="ACG804_000331"
     CDS             complement(46621..47742)
                     /gene="mnmA"
                     /locus_tag="ACG804_000331"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HFS4831292.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            48146..48745
                     /locus_tag="ACG804_000332"
     CDS             48146..48745
                     /locus_tag="ACG804_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFS4831293.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(48883..50169)
                     /gene="efmA"
                     /locus_tag="ACG804_000333"
     CDS             complement(48883..50169)
                     /gene="efmA"
                     /locus_tag="ACG804_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HFS4831294.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(50440..50784)
                     /locus_tag="ACG804_000334"
     CDS             complement(50440..50784)
                     /locus_tag="ACG804_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HFS4831295.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(50921..52066)
                     /locus_tag="ACG804_000335"
     CDS             complement(50921..52066)
                     /locus_tag="ACG804_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HFS4831296.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(52246..53220)
                     /locus_tag="ACG804_000336"
     CDS             complement(52246..53220)
                     /locus_tag="ACG804_000336"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFS4831297.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(53300..54175)
                     /locus_tag="ACG804_000337"
     CDS             complement(53300..54175)
                     /locus_tag="ACG804_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HFS4831298.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            54305..56212
                     /locus_tag="ACG804_000338"
     CDS             54305..56212
                     /locus_tag="ACG804_000338"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M13-type metalloendopeptidase"
                     /protein_id="HFS4831299.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(56753..60031)
                     /locus_tag="ACG804_000339"
     CDS             complement(56753..60031)
                     /locus_tag="ACG804_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="HFS4831300.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
BASE COUNT        17302 a        12492 c        10878 g        19478 t
ORIGIN      
        1 actgtagaca tcatccataa aatggacttt gtctacagtc tgaaatcacc actgatgatt
       61 ttctcttttg cgtctgaaac tgcctgatag gcttcctctg ataattgtcc ttttgtcaga
      121 tctacccctt cttctttcaa accaaaggtc aaatgcttgc cgccaggaaa tttatcgtta
      181 tgagaagttt ctgcaaattc tttgacttct gcaccgacat ttttctttgt agaagtcaac
      241 gtgaaattcc ctgtctcgcc gttctccatt ttataatccc cttcatccgc ttgatcgcga
      301 tctacaccaa tcacccatac ttttctgcta tagtcgtttt cattgcgggc ttttgcttct
      361 tggaacaccc cagctccagt acttcctgcc gcctgataaa gaatatcgac tccctctttg
      421 tacatagaag cagcaatagc ttttccttta tctagcgaat cataggatgc agcatattgt
      481 acgttaacag taatttcctt gttcagtgct gtggcccctg ccttaacgcc agcttcaaat
      541 ccgctttgga aacgttggat cacgggccct tccattccac caataaagcc tacttgatca
      601 ctttttgtcg tatatgcggc agctagtcct gctaaatacg cactttcttg atctttaaag
      661 gttgctgatg agatattctt tttcccagta atctcaccat ctaccaaggc aaatttcaac
      721 tttggattat ctttagcagc attttccagt tcctctgctt gcaagtagct caagctaata
      781 atggtggtaa agccgtttct gattgcctga tcgatattgg tactgttatc ctctggattg
      841 ttcgtttcta tatacgtaaa atcttttttt gctgtcagct ttttctcttt tccccaagcc
      901 tctaatcctt cccagccagc ttgattgaag gagcggtcat caaccccgcc aaatccaaga
      961 accaaagcga ttttactttt ctctttttca ctttgcttct ccccctgaga ctgactacag
     1021 ccgactaacg ttactaatga caccaaaaac aacaatgaaa caagtatttt cttcaaaatt
     1081 tttctcccct ttttatgtgt cttgacacat tgaactttta aaagtatagc ataccaatat
     1141 atagaacact actcttcaac gaagattttc cgtttcccaa tttctccact atcaaaaaac
     1201 cagcaatcac ttctgactgc tgttttttta tagctgttat tctgctttta ctggactact
     1261 tatattctca gctaagtcct ctaaagcttc gatatcatga atcaagtaat aattcttttt
     1321 cttttcgata atattctcct cacgaaaatt cgtgattgtt cgtaaaagat gtcgataact
     1381 gacatttaag attgaggcgc aggtggttaa ccgaaatgag aaacgttcgt tttcgtgatg
     1441 ggtcaaaata aactttgcta aacgagtttc aacaggttct gtcagtgagt tcgccaaatt
     1501 tatcccggaa tttaaacgat aacttagtaa ctggcaaata ttctgcaaaa agcgaacatc
     1561 tttttgaagc tgtgttcgat attgatttag cggaatgctg atacagatgc acttagtcac
     1621 tgctttaacg ctgcttttcg gcgataattc ccacaatgaa gaggcttcgc cgagtggtgt
     1681 agcgggcttt gcgtaatcga tgcaaatatt ttgtgtatca gaagaatacg agtacaccat
     1741 taccgtccca tccactaaaa aatacaaata atctgaggtt tttcccgttt gaatgaggtg
     1801 ctcttccttt tcaaaaaaaa gtaaagaagc cattgccaat atatctgaat ccatataatc
     1861 ctgcaggttg tgcttctcaa cgtaagcagt taattgcttc gtatcatgga tttttttcat
     1921 gaaatcgtca cctctaagaa gtttttcttt attatagctt agattgtttt tcggctcaat
     1981 acgaataatt atttataatt gtttgtaaat tgtatgtaaa agttgtgtaa aataggacgt
     2041 gcgtcacttc attgattttg attccctgct atgatttaga cgtattagaa attatatcca
     2101 acaggaggag aaaaatgcag ttcaaacagt tagcaaaagg gttcatcgga gtcatgttat
     2161 tgaccacttt ggcggcctgc ggttctggga atacaagtag cagctcagaa aaagagagca
     2221 aagaaaaatt agttgttcaa ttcgttccaa caaacaatga tggtagtatg gaggcaaaag
     2281 caaaaccatt tgctaagtat ttatcgaaaa agttagatcg tgaggtagaa gtgacgttag
     2341 ctactgatta ttcaacgatc gtcgaagcga tgtcttctgg tcaagtcgat gtcggaatta
     2401 tgccgcctgc agcctatgtt caagcaaagg atgctggagc tgcagatgca atcctgactt
     2461 ctcagctcgg cgattatgat caagaaactg gcttgccatt aaaggacaaa cttacgaaca
     2521 cctttaaagg agaagtattg gttcgtgccg atagcggatt gaataagtta actgatttaa
     2581 aaggaaaaaa tatcgcaacc ttaagtccta actctgctag cggctacatc tatcctgtcg
     2641 ctgaattgaa agatgctggg attgatccta ctgcagatac aaagatgacc actgtgaatg
     2701 atattccgag tgagattacc gcagtgttga acaagcaaat ggatgcggcg tttgtttttg
     2761 aaggcgcgcg aaatgttttt gcttcgaatt tcccagataa tgatttattt aaggatttaa
     2821 aagtcctgta cctgacaaaa ggcgatattc cgaatgacgc aatcgctgta cagcctgaca
     2881 tgtcaaaaga tttaaaagcg aaaattaaag agaccttctt aaatatgaag gatgataaag
     2941 atggcaaaga agcaatggct ttgtgggggc atcagggcta tgaagaagct gctgattctg
     3001 cctatgacac gatcagagac tacacgaaaa aagcagcaga ataaaacatc agtaagtgtc
     3061 agcaagcttt tttttgctta cacttaaaaa aatggagaag gataatgatt atttttgaca
     3121 atgtttcgaa ggtctatccc aatggcgttg ttggcttgaa ggatattgac ttaacaattg
     3181 aagatggaga atttgtttcc atcatagggt tgagtggtgc tggaaagagc actctgctgc
     3241 gcagtatcaa tcgcttggca gaaaccacca aaggagatat tcgcattaat ggaacctcta
     3301 ttacaaaagc gaataaaaaa gagctgcgac agattcgccg ccagattggt ctaatctcgc
     3361 aaagcttcaa tctggtaaag cgtagtacgg ttcagaaaaa tgtgctatct ggacgtttgg
     3421 gctattactc cacttggaaa agtattttag gtctttttac gaaggaagac taccagcaga
     3481 caaaggaagc actggaaaaa gttggtttgt ctgataaatt gcagacacgc agtgatgagc
     3541 tcagtggtgg gcaacaacag cgagtatcca ttgcgcgagc actcgtgcag caagccccca
     3601 ttattttagc ggatgaaccc gttgcatcat tagatccaat cacgactcaa aaggttatga
     3661 tggacctaaa aaatatcaat caaacgatgg ataaaacagt cattgtcaat ctgcattcag
     3721 tccctctggc tcgtgagttt tctacgcgtg tgctcgcgtt aaaagctgct caggttgtct
     3781 ttgatggtcg tccagacgac ttaaccgatg aacgcttaga gcaaatttat ggcaatgcaa
     3841 tctttgaaga aaaggcaggc gaaatcgatg agcttgaaag aaaccgttca ctttaaatgg
     3901 tataaacacc tgcttattct tctgttctta attgtttgtt ttcaaggaag tgcctggatc
     3961 acgtcagctg atttttctca ggtttttcaa aactccaatc aaatgactgt ctttttatca
     4021 cgcttcattc atccagactt tagctattta cctaaattag tcgagcctat ggtgaaaaca
     4081 cttcaaatgt ctttgcttgg aacggtcatt ggcttaattt tagcgatccc tgttagtttt
     4141 ttagcgacca ctgtagtgac agaaaaccgt cttctttcta ccatctttcg ttttctttta
     4201 ggtttagtac ggaccatccc taccctgctt ttagccgcgc tttttgttgc tgtgtttgga
     4261 attggtgaag cgactggcgt gttgactatc gctgtcttta cttttggtat ggtgtcacaa
     4321 ttaatgtttc aagcaattga aaccattgac tttggcccga ttgaagccgc tgcggctgtt
     4381 ggagcaaata aaatgcaaat cgctatttgg tcgatcgctc cacaagtttt gagtcagttt
     4441 gcgagctatg ctttttacgc gtttgaggtg aatgttcgtg cttctactgt ccttggatat
     4501 gtcggagctg gtggtattgg cgttattcta aattcctcac ttgcgctttt gaattatgaa
     4561 cgagtttcaa tcattattct aacgatccta gtaactgtcg cgatcgttga taaattaagt
     4621 gaacgtgtca ggaggtccct gttatgatgc ttcgtgaaat gaacagaaga acccttttat
     4681 cattagttgc tttagtgatt ctcgttattt tgtcggccgc tactctggat tactctggat
     4741 taagcacctt ctctccttcc atgggaatgg acgttttgag agggttaggt cagcctgatt
     4801 ggcagtttct atatgatggc agcggcgagg atttgattag tttgctatta ttaaccattg
     4861 gaatcgcctg tttagggaca atgatcgcta cggtattagc gattcccatt accttgatca
     4921 gtgcggttaa cctctggcaa gcacatccat gggtaacaaa aattggcaag cttatctgta
     4981 atgttttacg agcttttcct gaactagttt ttgcaattat ttttgtgaaa gtcgtcggac
     5041 ctggcccctt tgctggtgtt atggcgattg gcgtccatca gatcggaatg cttggcaaac
     5101 tttttacaga agaaatggaa gcgatggatg agcgacttgt tgaagaaatg catgcggtag
     5161 gagcaaattt ttggcaaacg attttctttg ttcgcatccc ctatttgatg ccgatttatt
     5221 gttctttagc attaaatcat tttgaaatag cggttcgtag tgcggctacc ttaggcttag
     5281 ttggcgctgg cggaatcggt gctccattga tattcgcgat tcaaactcgg tcttggagca
     5341 aagtgagtat tattttgatt ggcgtagtcg taaccgtgtt tattttagat caaataaccg
     5401 gaattataag aaagagattg agataagaat gaatatattg catatatcag atatacactt
     5461 tcgcagagag tatgaggctt gtgaagaagg ctataaggga atgctggcta cgatgcagaa
     5521 tccccttatc cctctggagc aatgcattca tcatctcctg cagcaaacac ccttggacct
     5581 tgtgattatc agcggagatt taaccgaaga tggcgaaata gacgattatc gatacttgaa
     5641 gacttggctg gaaaatgcgc taggagaaac gacgattctt gttactctag gcaatcacga
     5701 tatcaaagaa catttttggg taggctggtg cgatgaagcc gcctcttctg ccccgtacaa
     5761 ccagatagtc aaatatcctg agtttacagt gatttccttt gataattcaa gctatggata
     5821 cgcagatggt atagtggacg atcagcaatt tcaatggctg aaaaaagcct tagagcaaga
     5881 aaaagaccaa ccgattttct tggtcaccca tcatcatcta ctgtctcacc aaagcagtat
     5941 accaaaatgg cctggtaccg aacgtttctt gaagctaatc gcaccttacg atattcgctg
     6001 tatcctaaac ggtcataccc atcacacatt tactgatgaa attaatggga tcccctattt
     6061 tactgtatcg agtatgtcct ttgttggtga agatgaaggc gatggcttcg tacgctttga
     6121 agaacgtcat gggtataacc tttatcatct cgatcaagga aggattgttc gccagacaac
     6181 agaaaacttt attccaggca acattttaaa aacacttcaa atgaaggatt aaggcattat
     6241 aaatcaaaaa aagagaccga acagctgaat acgcttcggt ttttctattt tgagtcagct
     6301 aaaggagcac gcagaatgaa cattacgttt ttagagacaa gtgatatgca tggctatgtt
     6361 tcaccaacag actattccgg cagaaccgat ctggccttag gaacggctaa agtatcgtcg
     6421 aaactgaagg aattacgggc aaaagcagat ggaccggtaa ttacgatcga aaatggtgat
     6481 ttcatccaag ggtctccttt gagttattat cttgctaaag aatatggttc agccaaagag
     6541 cttacagact tgattaacca aatgagctat gatgttcaag tgttgggaaa tcatgagttt
     6601 aactatggtg tggattatct cgaggaagcg attaagaatt atcaagcgcc tatattagga
     6661 gccaatatgg tgaacaaaaa tgaccaacca tactttggaa acgcctataa gattatcgaa
     6721 aaggtgggtg taaaaattgc tatcttggga ttaacgacac aatacattcc tcactgggaa
     6781 aagccagaaa ccttagcagg aattacgttt aagagtatcg tcgaaacagc aaaagaatat
     6841 gttcctctat taaggaaaca agcagacttg gtaatcgtta gttaccacgg cggatttgaa
     6901 aaagacttgt taaccggtga ggacacagaa gcgctaactg gagagaatga aggctacgag
     6961 ctattgcagc aggttgaagg cattgacgcc cttttcaccg gtcatcagca ccggaaaatt
     7021 gctgaaacgg ttcatggagt tcccgttgtt caaccaggct atcgtggcga gttcatcggt
     7081 gaaattcgtc ttaccgtcga gaaaaaagag gggcaagtgg ttgttacaga tcaccaggtt
     7141 gctttacact cagttgaaaa atcagagcct gatccagaaa ttcttgcagc gatcgtaccg
     7201 gtagaagaaa aactagagaa atggttggat caacccttag gtaaagtgaa cggaaatatg
     7261 cgtattaatg atccgatgca ggctcgtctt gaggaacatc cctatgtaga gtttattaat
     7321 cgtgtacaat tatttgccag cggctcagag atttctggaa ctgcgttatt caataatgaa
     7381 ggaaaaggct ttggtgagac gatcacgatg cgggacgtca tcaccaacta tatttatccg
     7441 aatactctgg cagtgattca aataaatggt gcagatttga gagcggcgtt ggagcagacc
     7501 gcaaattatt tagctgtaga aaataaccaa atcgtattca atccagcctt tattcagcct
     7561 aagccccagt actacaatta tgacatgtat gaagggattc agtacactat tgatatgaaa
     7621 cagcctgttg gacaacggat taccgaactt cgttttaaag gtcaccccgt tcttccgcaa
     7681 caaatgctgg aagtggtgac aaatcaatat cgggcaatcg gcggaggaaa ttatgcgatg
     7741 tttggtgcgg agaaaattgt ccgagaaatc caaatcgaca tgaccgaatt aattgccgac
     7801 tatttgaata ttcacccacg catcgaagca aaagtgaatc ataattttca agtgattttg
     7861 tagtatataa ataaaaaatt caaaaaggtg tgagcagttt tttgcccaca cctttgttat
     7921 gccaaattgt taggctgtct gatttccatc cagccattct ttagccagcg atctacctca
     7981 tcaaaacaaa aaattttcct ctgatggttc cttaaataag actattttga tcctttttcc
     8041 atgaataaga ttttgcatca gacaatactt catttctgaa aaagttgcgg caccaatata
     8101 gcctaatacc cctttccgat cttgattaaa tacaaaaaat aaatccgctg ctgcgatatt
     8161 taaaaaaaag tcgtcaagat ttctggatac tctttgtcta ggatcggaca tgagcgagga
     8221 taatcaatta attcaatgcc ttttttactg aaatcttttt ccatatctcg atattcttct
     8281 tggaaaacaa tacttccaga aataacagct ttcacaaaat tggcctccat ttttttattt
     8341 ttcagacact ccaccatacc ggatacctct caaagaaaag acatagcaaa aatcaatagc
     8401 agctatctct ccacggtttt ttactggtaa ttttattttt cttttggaaa ttgtatcagg
     8461 aaggtcgttc cttcattttt tcggctggtc acttcaattg aaccgtggtg caggcgcact
     8521 agttccttca cgattgataa tccaagacct gactcgccta tctttgtatt tttacttgac
     8581 ggatcggctt tataatagcg atcccaaatg tttttttgtt cctcttcaat catgccgatg
     8641 ccattgtcct cgacagtaat aaatacaggc tctttgtcaa atgatgttgg taaagagaaa
     8701 tcttagaata atttggacag aacagaaaga agaaactctc tttctgttct gtttatttgg
     8761 ttaaaaatgt tttgccatga cgaatcatga tccgtagttt gaaattgtaa aagctgcgaa
     8821 agccgtacgc attgcgtttt aatactttga tgtggttgtt taaacattcc aatggtccat
     8881 ttgaatagct gtagtgaagc gcattttgga tctgtggcag aaacttttta aacgttcgta
     8941 aagtggttgt ataggtttca ggaagaccgc tgacttctct gtttaaacag tcctcaaata
     9001 atgactgatc tcttttcttt accgcataaa gaatgtcttg gtataactga tagccttggc
     9061 gcaggttggg acaagcagat aacagtcgat cgacaatctc actttcagtc aaataatctt
     9121 taaaactggc acgccaaacc cttttttcgt agtttaactt tgcttcttct ttttgtagga
     9181 gtttccaata gcgtttcaat tttttcccta accctcgttg agagtgggaa gttcctttaa
     9241 gccgtgccgt ggtttctttc actcgatgat tcaagaaggt tctgccaata tgttggacga
     9301 tgtggaaacg gtcgatgatc aactgagcat tcgggaaaag ctttttcacc aatgaaacat
     9361 aaggcgcata catatcaata acaatccatt gaacggcttc acgagtcgct aatgaaaacc
     9421 gagaaaaata gcattctaaa taaggcaagc gtcgattttc gacaatatcc aataatgcat
     9481 ggctttgtcc gtccatcatg ataaaactca ttgcactggc aacacttcga accgatttga
     9541 attcatcaaa gcataagacc tttggcaaag cctgtttgaa aggattcaat gggcggtaga
     9601 atcgcttcat gacacgatag accgaagaag tggaaatatt tttctgacga gcgatttccg
     9661 tcatggaagt attctctttt aagcgagcaa tgacagacca acgaactttt tgactaatga
     9721 aacagtgttt ttcagcaaca gaggtatccg ctacgaatgt tctttggcaa gacttacatt
     9781 taaatcgttg tttcttcaac tccagataag tgcgatactc agacgcatca ttcagtaaca
     9841 accgaacggt tgtcgtcccc caacgaatga tcctagaggg gacgacacaa agacaatggg
     9901 aacactcttc tggcttgtac agaagagttc ctttgtaaat catggatttg agtcaatatc
     9961 ttggacacat tttagtagag acggttaagc cattttttct tttgctaatt cttcaaattc
    10021 ctgtggggtt agatagtgaa tcgagctatg gattcgattt cggttataaa atccttcaat
    10081 gtagctaaat agcgctcgat ttgcttcttc aaaatctgag tagctagtcg tgtagacttc
    10141 ttcttttttc aatgaggcat ggaaagattc gattccagca ttatcataag gtgttccttt
    10201 tctactataa gaatgcctta ttttgttggt tttaagccat tgttccactt ctcttgctgt
    10261 gtattggctg cccaagtcag tgtgtagaat cattccttct ggaatgtgat aatgtatttt
    10321 tgctttattc aatgtttgaa tgacacaatc cacagtcatt cgttttgaaa atgtataact
    10381 aataattttt ttcgtgtgta aatccatgat tgaagataag taacaccaac catttttctt
    10441 agtaggaatg tacgtaatgt cagctgccca tttctcacag atcgtttcag tagaaaagtc
    10501 ctgatttaag agattctctt ttgaaatgat cggtttatta gacctttgag gtctatattt
    10561 tttaactaca atcgacctta aatttaattg tttcattagc ttttggacat gtttaagaga
    10621 tactgaaatc ccttctttta ataaaacttg atggatcttt gtggcaccat agcgttgttt
    10681 attcgtaaaa aaaattgttg aaatcttctt tttcaactta ttatttctga tttctgtagc
    10741 tgtcaacggt ttattcttat aaaaataata gacacttcta gggatttcta ataaccgaca
    10801 taacaaagaa acagtgtaat ccttacacca tttttcaata aattgaacaa gcgaatttag
    10861 gttttccgag agaatatggc tgcggctttt tttaagattt caagttcctc atttaaacga
    10921 gcattttctt ttctcagttc agctacttct tttccagtca gtcctgtgga ctgatcaggt
    10981 aaatataaat tcttccattt gtaaatcgtt gcttcagata agccatattc tttcgctaac
    11041 cctcgaacag aacgtccagt ttgattcagt tcaacaatca tttgtttaaa attttcttca
    11101 tatcgggtca taaaaattca tcctctcgta gataagttta atttattctt gtctctacga
    11161 aaagctgtct aagatttgat actaacacca agttatcttt agaaccattt cagatacata
    11221 tgaaacaatt acatatgatt ttttcataaa aaaacagtac tgtctagtag tataaaatat
    11281 acaaatttct taaaaatttt ttcactaaaa tcactacctg aaacagtcta aaacacttat
    11341 atatcaacgt ttaatgaaac tatctccgtt tcatttcaga tacaaataaa tatagtcggg
    11401 ctccaaatcc gaaaaaaaat acccccagta gcttatccta agctactgga gatgtataag
    11461 tacggtcata taacaacggg gtagggtaaa taaatgaaaa agatggaaga atcattattc
    11521 aataactttt ttaaatactt cgttgtaatc agttacctgt ccgttcttaa ataccacaga
    11581 ataatctttt ttcccatttt caagtaaccg aagtggaatg tctttaccaa cttgctctgt
    11641 cactgcatta ctgatacctg ttagattagc taataaatct gataaagatt gagcatctgt
    11701 agaaatctct gtatcagtat ttatcgtgat tcctttatct tcatttacaa gcttccaagt
    11761 aggtggtata gctgtgtatg tttcgatgaa tgaatcaatt ctttcatcta tcgtcttccc
    11821 agtatctact tctgtctcat tactcttaga tgaatcgatt ctttcatcca tcgtctgctc
    11881 cgtaactgct tctgtctcat tattctcacc ggaaactctc ttcacaccca aacttatata
    11941 ttgtccatct ttagtgtgca tagttaaaat tcccacgctt ttactaataa attcactata
    12001 accagttctt tcaatagaga cttcaatgta tttcacacta tcatactcaa aagaaaaata
    12061 gacatgtaaa agcattttgt tgtttacatc tacataataa tcctttgact ctacttgaga
    12121 ccttcctata cggaatacag ctttactgtc tgatatctct ataccagcat ccttattatt
    12181 aatctgccaa tctccaagta gctcttctgg caagctagta gtttcttgtg aacactttac
    12241 cacttcactg gtagaggtcg aaacattcac ctccgcactg ttagaagaat tttccaagga
    12301 atcaggagcc ttagcacaac caacaagtct ttatatattg tgcagccgat attttcttca
    12361 ttcagtacac ccttgaaata tgcagtgtta gataaagcag ttcgtcctga tttgctgagg
    12421 cacccatctc ttcttgaacg tactccttga ttttcaaggc cgcccgatac tctttcggaa
    12481 aacgctgctt cactgaagcc agcaaaaaat catccttctc cggcaactct tccttcttaa
    12541 tcattcgggc aataaaaaac tgtaaatgcg tcacaaatct taagtaaagc atcgaatctt
    12601 tatcaacctt tttttcggga aacagatatc ctagcatagc caagatatcc tttagtgctc
    12661 ttaccgagag catggtttct tccatatttg cttgttcact ttgggcattt acaatgtgaa
    12721 acgcaatgtt tccagcctcc tcttctggca actgaacatt catttttttg ttgatcaatt
    12781 ggatagcata gcagccgatc tcaaattctt ttgggtaata cttttgaatt tcaatcagca
    12841 ggcgattttg aaaaacaatg cctttttgac tgcgttcaat ggcatgcttc aagtgatcaa
    12901 ccaaggtaaa aaatagactt ttattcagct taaagtcaaa cttggcgttg gcataatcga
    12961 taattcgctt gacgcaaata attagatcat ccggagcagc ctcaaacagt ttaatgtaat
    13021 ccttttttag agcatcagaa agtgaatcta atttaaatac tttttggatt ttgtcagccg
    13081 gaaccaaatc gcctttcttt agttgaaatc caatcccttt ccccatcaaa attacttctt
    13141 tgccttgctt atctaagcaa agaattaaac tgttgtttaa cgttttaatt actctcatta
    13201 gattcaccgt tctctctaag ctaagccatt tcttgcgatt actttttgat accaaaagaa
    13261 gctttctttt tttattcgtt ttaattcttt aagattctca tcggttcggt caacatatat
    13321 aaaaccataa cgcttattga agccttgatg ggtactaaca acatcaatcg ctgaccaagg
    13381 taaataacca aaaacatcta caccatctgt taaagctgct tgaatagcca gaatatgttt
    13441 ggctagataa tcaattcgat cctggtcatt aattcgtcta tcttcctcaa ctatgtcggg
    13501 tgccccatag ccattttcag taattaaaat aggtaaatca tagcgatcgt acaatttcct
    13561 caatgttaat cgtagtccag tagggtcaac tacccagcca tatggcgttt tatctacata
    13621 aggattttca gctgcccggt agacaccttc ttctcccaac atgatctgtt gatcccccgc
    13681 tctagcggaa acatctgatc cgtcattttt gctggcagcg atggtggcag ttgaataata
    13741 attaatcgca ataaaatcgg gtttaccgga ggataaaatt gcctgatcct ctgcctcaat
    13801 tttaggatat aatccacgat cattcaaata gttttcaaac aaataattgt attttccccg
    13861 aactgctaca tctaagaaag accagcctct caatgtttcc caattatggg ctgcaattgc
    13921 atcttctgga ctggaggtag cttgatacat agccgttaaa ttgattgctg gaccgatttt
    13981 tcctttaaga ttcaactgat gatacaagtg aattactcta gcttgagcta ataaaacatg
    14041 gtgattaatt tgaaagagtt ctttttttga aggcagctct ccacttggtg gcaaaccaat
    14101 cgctccagga tgaaggatca tcgtgttttg ctcattaatt gtcagccaat agttcacctt
    14161 gtcaccatac tcagtaagca atacctgtac atagtccaca aaataatcga tagttgctcg
    14221 atttaaccaa ccgccctgct cctctagaaa ataaggtaaa tcgaaatggt acatggtgac
    14281 aatcggttcg attccctgat tcaggcattc atcaattact tgatgataaa aagaaattcc
    14341 cttttgattg gttttattat tttcaatatc cataattcgc gtccaagcga tggaaaagcg
    14401 aaaagctttt aagcctaatt ctttaaacag ctgtatatct tctttatagt gatggtaaaa
    14461 atccgaggca acttcaaaat tagctacccc ttctgtatgc tgatacttgt caataataga
    14521 cggttgtttc ccatcctcct gataggcacc ctctgcctgg taggcactaa tggaggcacc
    14581 ccataaaaac ttctctggaa atgctgaaag ctgtttgtat tgcacaaaaa tcctctcctt
    14641 aactaatttg catcaatggt tcgtgttcct ttaagcttcc gcttgcttca ctaattcctg
    14701 cgtaattttc actgttggtc actaccacaa tcactgtatc atcgtagcca gcgtttctaa
    14761 tggcagcgaa atcggcgttg attaataatt gtcctgctga cacctgatct cctgctttta
    14821 caaatacttc aaagggttcc ccttttaaat tcacggtgtc gatccccaca tggatcaata
    14881 attcaatacc ttctttagaa cgtagaccaa tcgcatgttt agattctaaa atagtaatga
    14941 cttctccctc aacaggtgaa taaatgctgt tttcttctgg atgaatggct acgccctttc
    15001 ccaatagtcc cttagaaaag acagcatcgt tcacttcaga aataggacac acggttcctt
    15061 ttaccggatt ttcaacaatg actgcttcgg ctattgccgt ttgctctgat tcatcagaag
    15121 tatcgtcaaa tccaattaga taagcaatga taaaggttgc aacaaaggcg attacacacg
    15181 taataattgc gtgaacaata ttcattggat tttctccaat aaaggctggt aaggctgcta
    15241 agccagggga aacaaaggca tatctgacta aaccgctcaa gccagcatac aaaccagcaa
    15301 ttgcaccacc aatcatggaa gcaactaatg gttttttcag cttcaaggtt actccataga
    15361 gtgaaggctc agtaattccc attaaagcag tgatcccagt ggacacagct agctgcttca
    15421 actctttgtt tttagttttc gcggctacag caaaggtagc acctgattga gcaatattag
    15481 aagccagcat tcctggccca ttgatcattt cagaacccgt actgctcaat tgcatagtag
    15541 cgattggcgt cattgcccaa gctgtacccg taaccaccaa aaatggctgc aaaccaccca
    15601 tcaaaaatgg aattaaccaa gctgctttgc cgttaatcca ttcagccccc attgctataa
    15661 gatcgttcag caacgttcca aacggtccaa tgacaaccaa cgctaaaggc cccataatta
    15721 aaaataccag catcggctta gtaaagaatt taataaacga aggcgaaatt cgatccgcaa
    15781 agggctctac ataggacatg atccaaacag taaagataat cggtaaaact gatcccgcat
    15841 aatctgcagc taataccgga attcctagaa aagaaacggc atcgccagta gaaaaaagct
    15901 gtgaaatatt tggatgaagc aaaatgccag caacagtaat cgccaaaatt gggttgacat
    15961 caaactttat ggctgcccca taggctaata gtactggcat aaaataaaag gctgcatcag
    16021 caatagtatt caaaatgatg taagtttgac tactgtctga tagtacacca gtcaaagtca
    16081 agacggccaa aatggctttt accatcccgg cacctgttat agctggaatc atcggtgtaa
    16141 aggtggtaga aatgacacta atcaatcttg aaataatact ttcttgattg tctgaagagg
    16201 ggcccttttt aattgaagtt cccacttcct tttgaatttc cttgaaggct gtttggactt
    16261 cattgccaat caccacttgg tattgtccac cgctatccac cacactaatt acaccaagtg
    16321 ttttttctaa ggctttcgta tcggctttcc ttttatcttt gagttcaaaa cgcagtctgg
    16381 tggcacaatg ggttaagctg accacatttt cttttccccc aacctgttgc aatacatttc
    16441 ttcctacttc tctgtaatcc attattctct ctccttaaag cagtaaaaaa gaccaagtca
    16501 aaccacgccc caatcaacat tgaagtgtta gtttgtcttg gtcttgcctg cataatcagt
    16561 aacatgccaa taacgttatt ttgctgtaat ccaataatag cacattatga tagcgcaatc
    16621 aacagggaat ttaatttttt atcttttcgt ttgaccgtat agggtaatat aacagttaga
    16681 tcacatcaac tagggtatat ctgcgtatac ttactgctaa aataagtata tctaatatta
    16741 actataccag taaaaccatt cctacataac cagcgggaaa ttcccaaaat cgtgaaagca
    16801 tcaaaaatgc atataacgga tcacacaact tcaacaattc tgctcttggg aaaaattgat
    16861 gaatttggtg agtaaaggat ggaataaaca gcattccaac aatataggca acaatagtga
    16921 tacttgtttt tttggtaaaa atcagtaagc aatagccaat ttcaatcatt ccgagatata
    16981 aaggtatcga tagaatgatt tgggctagta ttcttaaaaa ttaactagca aatgtttaaa
    17041 ctgatttatt tctaatctac atgtagtaag tatttcaatt ccaccaatta tcaataaaaa
    17101 taccaaacat atccataata attttttctt tttcatttct tttatattgt tataacagtg
    17161 aataacataa aaattcccga caatcattgt aatatttttt tgtcacctgt attagtattt
    17221 aatttatagg aaactataaa aactccctag tgaatttaca cctttgggag ttcctgtttg
    17281 gacggtatgc ataatacatt taaatcaatt taacattaac acctcagcat atggtatctc
    17341 cacatatata cggtctttct ttggatagta ctcaatattt atgttgatag cacttccatt
    17401 gtctaatata gctttagccc ggtatgtgtt atctccattt tcatgagtaa tcgtcacatc
    17461 atcacatgat cgatttaagt tgtactgttc ttgtaaaatc tgtgttacca atggtttcga
    17521 tgacttctct aatccagatg tacctgtcat ttttgaaaaa atgataccta taatagccaa
    17581 gacaacgata actataatga taaacttctt gttcatattt actttattca actttttatc
    17641 tcctatctcc aaaataattt gctcttatcc ctcttatcag tacattgaca tccctaaaag
    17701 tacaccaaag attgctccag ctacccctgc tatcatcaaa atcgtaccca tttgttcatc
    17761 tttatctcga tataagtagc ccataataac agcaacagca ccaaatacaa caggaataaa
    17821 tgctaacgct actaccatag aaatccaacc aataatcaaa tacagcttcc ctgtctcttg
    17881 tccatgtacg atttgttcct tcatttcatt aattgtctgc tcagtacttt tctttactgc
    17941 gtctgctcca gttgtctcat ctgtttcttg tagtgctccg caaaactggc aatacttact
    18001 ttcatctgtt atttctttgc cacattttct acaatacatg tcttctcctc ctaaaaacat
    18061 tcaattgttt attagttaac tgtttacttt attaaataca tcagaaaaca gctcattcat
    18121 tggtacactt aatatctcag aaagcatctt catttgatag ggtttaggaa tcgttctccc
    18181 tgtttgccac gaacttacac attgctgtgt aacattcatt tttttgctaa ctccgtttga
    18241 gaaagtcctt tttcttttct gtatcggctg agattactta cttttttcat gattctcccc
    18301 tcctgtttta ttatatacaa caatatgatg tatttcaact cataaaatat aaaaaaactt
    18361 caaataccat tacaaataca acaacttgtt gtactatact gagatggggg tgtattaatg
    18421 aaacagaaac aatatgcaaa ggtcattaga gaaaagcgaa aagctctcgg gtggacacaa
    18481 aaagaattag ctgaaaaaat cttctctaca caacaggcag tagcaagatg ggaaaattct
    18541 gtaacagagc ctaacctcga tagcttaacc gctctttcta gagccctagg aacccctgta
    18601 agccattttc tagacaatgt tgtcgtagat tatgaggaag agtttttggc tctctatcgt
    18661 tctcttagca ctgaagatgc agttcgaaca attgactata tgaagctatt aaaaaggcaa
    18721 gaaaatgaac gcaatcagct attgaaagat tgaaaaataa ataacccacc gaactttaac
    18781 ggtgggtgta ttgagatgaa ataagattaa gagctatgga taacctgtct agtttaatac
    18841 aattgggtct tttctcttcc ttactctccg tccatcatct cttgttacac ttgtaaattg
    18901 ataaagagga actaattcaa ctcctgataa tatcaattct tttattactt catctatccc
    18961 tgctcctttt gctaggtaga ctaaaaaact actacttgct ttcacattgt atagtctctt
    19021 aatatcctta gaagctcgtt caagagtgaa tccttgttta acaaagtagc ctctgttttc
    19081 ttttaaagca ttttccacgc tgttattccc aacattacgt agacgttcac aaacagtgtt
    19141 agtaagttct ttctctgtca ttagatatgt tccttgccac gataagccct gtaaaacttc
    19201 atgtgcttca tctaaaatca attgtttttc cttgctaagt tctgatcggg aattttgagg
    19261 aaatactctt ttagcctctt tttcgttaaa acatatctta acccattcat aagaaaaata
    19321 ttgatatgta aaatgaaatt tttccagaag tggaaggata tcttcattca atttttgaat
    19381 cacagaagtt gcattaaaaa cgtctaatcg atagacattg cttctcttat gattaaagtt
    19441 tcctaacgct ttctcttcct ttaacctatt taggtattcg agcatcttca aaggaacatc
    19501 ttcatcatct aattttttta tcaatcctat aaaagtcata agtgatagta acttattaca
    19561 tttatctatg tcataagttt taccatagta aaaactcatt tttttagcta attgttcccc
    19621 cgacaaaata caagtcacac tttccttact atcatcaaaa aaattaacat cagaaagcaa
    19681 gacatcatag acacgtcgca tttcctctag ataattcctt attgtcctga aaagtttgtc
    19741 tttcattgat tcaagagtgt caaaaagtac ttttgattcc tctttcaatt ttcgaaaatg
    19801 tgtaggatac aagtctaggt tctctaatag ccaattaaat gtttctaccc gactgtcttt
    19861 ctttaaaatt agcatcacaa ctccaataaa attttcactg atatcacaat tactggaatg
    19921 acaataaaaa atggaatgcc cagttttact ggtaaaaata ctagcagagg gattatgatc
    19981 gttgtgaaac agacatctta agtttttact tgacttaagt aatttattca tatcaatggt
    20041 taacaatctt tcataaatct cattaaaaga catgtcggag gaatcaaaca ggcagtcttt
    20101 aaaccactgt ttcatttctt ctttgtcgtc attttttatc aacttaacaa aatcggtttc
    20161 attgactagt tcatactctc tccctgaatc actttgacaa tttttagaac atgtcatggt
    20221 aaaatcaatc ggaagctcag taatatctaa catgttgtct tcattaatta ttatcactgc
    20281 atctgactta tatcctccaa aaaacattct attcgaagca tttacattgt catcacaccc
    20341 ggggatgttc tttttcaagt attcgtaaac agcaaccatt ttaccatagt cagtaattgc
    20401 ttcttttaat agaaagacaa tcttgtattt ttctagattt tcagagtacc gaatactttt
    20461 ttgtatcgca aacgcagaat tatgaactaa attgatagat aaaacctttt ctatgcttaa
    20521 gtatctacta tcatctttac tcaaatctac taccttcccc ttctcatctt taacagtgtt
    20581 atcgacatcc agaataatta ctctggtttc cacaaaactc tccttgtcat tgcctttatt
    20641 ctttgtcttg cttggaataa atgattgtga tgaatttagt atctctacaa actcatctct
    20701 tgtaacttct ctatagttat ctaaacacct atctcttaca tcagtttttt ctttttttgt
    20761 aactggcttc tctaataatt tttctttatc tacataaatt ggaatattaa tcattgatgt
    20821 ttccatttgt gtttcctcct tataaaattc tgttaaagac taaaacatac agataataaa
    20881 aacaaactct ttattactat atgttttagt cttatttgtt tactcaacct ttataccgtt
    20941 ccatgaaact atcaatatca gattttttaa atctaatgac cgtatcaatt tttataacag
    21001 gtaacccgta ttgagaaaca tattttctaa tcgttcctac tgatacacct agatattcac
    21061 ttgcctgctg atagtccata tactctagag tgactccaga aataatgtct tctagcatag
    21121 gctttagcac tgtaattatc tctttcactt gttgttcaac ttgtatagaa acaatgctat
    21181 caatgatttg tagagacata tttccccctc ctttcgtgat tgcttgaaca aattttctaa
    21241 gaattatctt cgtatttttt gctcaaaata aaagtatttt gttattaacc gattaatcaa
    21301 acaaaaaatg attaccagtt catcgacata cacataatac ctcgataaaa aagaggtgtc
    21361 aatatctttg taaaatttat ttacaacacc cctttttcga ggtatactaa ttttaggagg
    21421 tgtggtcaat atgataaaac gtccaccaat aaattattta gaacgaaaaa agatactcgg
    21481 aacaaaaata aaagctataa gaaagagtaa aaaattaaca caaccagcat ttggtcttat
    21541 gattaacaac ggtcaattaa ttgacaaaaa aactatctac gaatgggaga agggaaccta
    21601 tttaccaata ccagagcgat tatcccgaat tgctgatttg ggaaatatga gtatagagga
    21661 gttagtttgt ggcaatgtag aagaatatat tttgggaatt attctttata gagatagcat
    21721 tgtactagat ggtataacat ttccagataa aaacctgttc cagcatcttc gtcaacagtt
    21781 cccaccagta cactctaatt tagatacatg gctggataga tattccaaat tagaaccaga
    21841 gatgcaagaa tttattgcta acaagacttg taataaagtt aaaaatgaaa aaattagtct
    21901 tttcaatatc ttaaaaatag aagaattatt catcaatgct attgtagaag aatttgacaa
    21961 taacattctt ttcctcacta gcagtataga agaactacta gaaagaatgg tagatgaatg
    22021 gctacctatt caattgaaag acatgtctta tcccgaagaa gctgtgagag aaattactga
    22081 taatataaac aagctagaac aaacgatttc atcaattggg aaaaaataca ctaagaaaaa
    22141 aatgaaggga ggtgatacca tctagtggta agtactcctt gtaaactaag aggagatgat
    22201 ttcatggcaa aaatatcaaa gtacaaaaag aaaaacggtc aagtggcgtg gatgtataaa
    22261 ggacacattg ccaccgatcc acgaactggt gaaaaaataa atactacgag aagaggtttt
    22321 agtagcaaac aagaagctca aaaagattat gacgagtaca gacatcaaat attatacggt
    22381 gttaaaaaga aagcacctga tatgacattt gaagacctgt ataatgaatg gataactcat
    22441 cagcgtacca gtgttaaagc ttcaacaatc gcaatctcag taagatacgc aaataatcaa
    22501 atacttccag catttggtaa gcttaaacta tcgaatatct ctgtcccata ttgtcaaaaa
    22561 gtggtagatg aatggcacag taaatatgaa agttacgatt atatgagaaa acagactgca
    22621 caaattttac gctacggggt tgcaatgcaa tatattgaca ataatcctat ggaaaaaaca
    22681 cttcttccac gaaaaaaaga gtatgagaaa aatcgtaaat tttactcaaa agaggagctt
    22741 aataatttac tggatgcttt taaagatttt ggtaacatga aacaatacgc cttcttcaga
    22801 ttattggcat acacaggtat gagaaagagt gaagtactcg ctttacagtg gaaagacata
    22861 gacacgttta ataaagaact acatgtcaat aaaactcttg ctgtagatga atttggtaaa
    22921 gttataattc aatctccgaa aacaagagct tctagacgag ttatctcttt agatactgag
    22981 actctttcta tcctcaacaa ctggaaatta cagcaaaaag aagagtattt aaaacttgga
    23041 tacaatacta gctctaaaga gcaacatgtt tttacaacag ttaaaaacac tctatacatt
    23101 ccaaacactg ttaatgattg gttaagatat attttgaaaa aatataactt gcctcgtatt
    23161 acacctcatg ggtttagaca tacacatgct agtttattat tagaagcagg agaatctgtc
    23221 aaggtagttc aacaacgatt agggcatgaa aatagtaaag tgacattaga catctatgca
    23281 catattacaa ataatgcacc taagaaaaca ggtcaagact ttgctgatat gatggctcat
    23341 cagtaaaaga gctggtcaaa atctggtcat ttctagtata caggcaaaac aaaaaagcta
    23401 gaacccttat atatcaaggg ttctagctcc tataacaggt ttacccaaca ctgccttcca
    23461 tctcataact gatcaatcga ttgagttcga ctgcatattc cattggaagt tctttggtga
    23521 atggttcaac aaagcccatg acgatcattt cagttgcttc agattcggtc aggcctcggc
    23581 tcatcagata gtagagttgt tcttctgaga tttttgagac tttggcttcg tgttctaaag
    23641 agacttggct gttgtggatc tcattgaatg ggatcgtatc ggatttcgac cattcgtcca
    23701 tgatgatcgt gtcacattcg atatgagaga tcgaacccgc actgtttttg gcaaaggtta
    23761 cttgtcctcg atagtttact tctccgccgt cttttgaaat tgatttagag acgatagagc
    23821 tagatgtatt tggtgcattg tggatcattt ttgcacccgt atcttggatt tggtttgctc
    23881 ctgcaaaggc gatggagagc atggtgcctc gtgcaccttt tccatctaag taaacacttg
    23941 ggtatttcat cgttgttttt gcacctaggt ttccgtcgat ccattcaacg gttgcgcctt
    24001 cgtatgcttt tgctcgtttg gttactaagt tgtacacatt gtctgaccag ttttggatcg
    24061 ttgtgtaacg gcaatacgca tcttttcttg taaagatttc tacgatggcg gcatgcaggc
    24121 tgttacttga ataagtaggt gccgtacaac cttcgacata gtggatgctt gctccttcgt
    24181 caacaatgat cagcgtacgt tcgaattgcc ccgtgttttc cgcattgatc cggaagtacg
    24241 tttgtaatgg aacatcgact ttgacgcctt ttggcacgta aataaaggtc ccacctgacc
    24301 atacggctga attcagcgct gctaatttgt tgtcggttgg cggtacaagt tttgaaaagt
    24361 actctttgaa taattcaggg tattctttca aagcagagtc agtgtcagta aagacgattc
    24421 ctaacttttc gaattcatct ttcatattat ggtacacgac ttctgattca tattgtgcgg
    24481 aagcaccggc tagataagct cgttcagctt ctggtatacc aatcttttca aatgtatctt
    24541 tgattttttc tggtacgtct tcccagtcac gagcgggttt gtcacttggt ttttggtaat
    24601 atttgatggc atcgaaatcg atgtctgaaa ggtcggggcc ccatgtttgc attggcattt
    24661 tgttaaatgt ttctagagat ttcagacgga attcaagcat ccattctggt tcgcctttga
    24721 ttcttgacat ctcacggatc acttcttctg tcaagccttc tcctgtactg aaaaccggtt
    24781 cgacatcatc gtgaaacccg aatttatatt cttctaattc tggtacgccc atgttctcac
    24841 tcctcttcct tgtggtaatg atggaaagct gcggtaccat cgttttccat tgcttttcct
    24901 agtgctttcc aggcaagtgt cgcacatttg atccgagcgg gaaatttagc tacaccacca
    24961 agcatagcag catcgcctaa ttggtcggga tctttgactt cttttccttg gacaagctgt
    25021 agaaagtcta cagttaaatg ttctgcttct tctattgatt ttccgatgac ggcgtctgtc
    25081 atcatcgagg cacttgccgt actgatggag cagccactgc cgtcaaaggc gatatttttg
    25141 atgattccgt cttttacatc gacttgcaat tcgatcacat ctccacatgt ggggttgttc
    25201 aattcgatct tgcttgtcga gtcagtcaag cttccacgat gatgcggatg ggaagaatga
    25261 tccaagatca cttgacggta taaattgtct aatttagata gtcccatgtt ggaaaaactc
    25321 ctttgttgcc atgattgctt caactaaacg gtcggcgtct tgcgttgtgt tgtagaaata
    25381 aaagctcgcg cgagcagtcg ctgatacttc aaggtacttc aatagcggtt gcgcacaatg
    25441 atgacctgct ctgacggcta ccccttccat gtctaaagct gtcgcgacat catggggatg
    25501 taacccatcc aaattgaatg caacgactcc tgtccgaaaa ttcgggtctt gtggaccata
    25561 aacagtcaat ccatcaattg cttgtaattt tggcaacaca taagcggcta gttcttcttc
    25621 atatcgatgg atattgtcca taccgagttt ttgcaaataa tcgattgcat ggcctaatgc
    25681 gatagcgccg gcgatatttg gtgtccctgc ttcgaatttc caaggtagtt ctttccatgt
    25741 actgtcgtat aattcgacaa aatcgatcat ttcgccacca aattcaacag gttccatttc
    25801 ttctaaccat tttcgtttac catataaaac accaatacct gttggtccgc acattttgtg
    25861 tccgctgaaa gcaaagaaat cacagtctag tgcttggaca tcaatggcca tgtgcggggc
    25921 agattgagca ccatctacta cgatgacccc gccgttttca tggacaagtt cagctaattc
    25981 ttgaacagga ttgaagacac ctaagacatt ggatacatga gcaatggaga cgattttggt
    26041 tttgtccgta atctttttcg ctgcatcctc catatccagg aagccttctt ctgttagttc
    26101 gatatatttc aagacagcac ctgttcgttt tgccaactgc tgccacggga taacattaga
    26161 atgatgttcc atgtaagaga gcactatctc gtctcctgct ttgatatagc ggtcgccgaa
    26221 ggttctggct acccaattca agcttgtcgt cgtaccacga gtaaacagca cttctgctgt
    26281 ttcttttgca tggatgaacg cccgtacttt ttctcttgct tgttcataat catgggtcgc
    26341 gcgttctgct aacgtatgga caccgcgatg aacattggcg ttatcgtgtt cgtaatagta
    26401 cgctaatgcc tggagtactt gttttggctt ttgggtcgtc gctgcattat ccagataaac
    26461 taaaggttca tcattgacgt cttgaaataa gataggaaaa tcattgcgta gctttttagc
    26521 atcgatcatc cattcaactt cccttcgatt acttcgacta attctttccg aacttgttct
    26581 acagggattg ctgttaagac agaaccgagg aatcctcgaa tcactaagcg ctctgcttct
    26641 tctttatgca atcctctact catcagatag tacatttctt ctggatcaac tcgtcctaca
    26701 ctggcagcat gtccagcagt tacttcgttt tcatcgatca aaagaatagg attcgcatca
    26761 ccacgtgctt tatcagaaag catcaagaca cgactttctt gttgggcatc tgcacctttt
    26821 gcccctttca agatgtggcc gataccatta aaggtcaatg ttcctttttc tcggatcact
    26881 ccgtgttgca aaatatgccc gatcgtatga ggggctttat tggttactcg tgtatcgatt
    26941 ccttggattt gtctgcccga gctgattgcc acgattttga cttctgcgtg tgcaccttct
    27001 cctgctaaat ctgagtcaaa gtcagcgatc acatgaccgt cattcatgac accaattgcc
    27061 cagtcgacag aagcatctcg taaaatgtgc ccacggcgat tcatataaga agtaatattt
    27121 tctcctaatt gatctacggc tgaatatttg atttttgaac cagctttagc gatgacttcc
    27181 acgatgatat tacctgatga ttttgctact tgttctttgg ttgtctggaa acgttccaga
    27241 taagaaaatt cactatgttc atctgccacg atcaacacat gcttgaagaa gtgctcatcg
    27301 gatgcgccat cttgaatgaa taaggactcg agtggttcat cgatcacgac atttttaggc
    27361 acatacagga aaataccgct gttcataaaa gctacatgga gtgcagtcaa ttggtcttcg
    27421 ttcatgttta ctgctttttt catataatat tcttggacta gttctggata ttcgatcatt
    27481 gcagtgaaca agtcggtaaa aatgactcct ttttctgcta attccacagg cagttgttca
    27541 aaaatcgtcc atgaaccttg ttggacaagc acaggattgt ctttcattgc atcaaatgcc
    27601 ggaatcgtgc ctgtttcact gatggtttgt gtttctttca catcaaataa cgaccagcga
    27661 tggaatttca cccgatcgat atgcggcaat ggcagttcat ctgctttcgc tagtgcgtct
    27721 tgacggaagg ttctcatcca atcaggttcg cctttactta aagaaaaatc atttaccgcg
    27781 tcaagataat cgagccagtt tttttctttc attcttgctc ccccttacgc ttcttcttct
    27841 ttatagtcga ttcctaattc tttactgata ccagcgtagc cttctgcttc cagacgttta
    27901 gctaggtcag cattccctgt catgactact cggccttcca tcatgatgtg aacgacatca
    27961 ggtgtgatat agttcaataa tcgttgatag tgggtgatga tcaatgcacc gaaattgtct
    28021 ccgcgcattt catttactcc tttagcaacg actttcaaag catcgatatc cagacctgaa
    28081 tcgatttcgt ctaaaattgc aaatgtaggt tctaacatca acaattgcag gatctcattc
    28141 cgtttctttt ctccgccaga aaaaccttcg ttcagataac gttcagccat ttcttctggc
    28201 atatttagta aagccatttt ttcatctaac tttttcaaaa atgccataac agaaattttg
    28261 tcgttttcat cacgtttcgc attgatcgct gcacgcatga attccgcatt cgtgatacct
    28321 ggtatctcac ttggatattg catagctaaa aataagccaa gtcgcgcacg ttcatctact
    28381 tccaagtcta aaacattttt cccgtcaaac aaaatttcgc cttctgttac ttcatagttt
    28441 ggattgccca tgatagcggc agataaggta gattttcctg tgccgttagg tcccatgatg
    28501 gcatggattt ctccggtttt cattgttagg tttacgcctt taaggatttc tttttcctcg
    28561 atcgacacat gtagattttt tatttctaag acagacatgc attatacccc caaattctct
    28621 ttcgttctca ctcattttag actaattgag aatgaagcgc aatgaccttc cttactaaaa
    28681 tcaaatatct tttatttatt attaaacaat tttgatttct aaattagaat aggtataaaa
    28741 aagatgagaa ataagccatt acagacttat ttctcatctt ttttgttcca taccttattt
    28801 tgcatcagcc tttactggtt taacagagcc gccccatttg tctgtgatcc attcttggac
    28861 ttctttgcgg tgaagcactt caatcagttt tttgattttg tcactgtctt catcaccttt
    28921 acgagtcgca ataatattca cgtaaggaga gttgtccttt tcaagcaata cggcatcttc
    28981 taatggattc aaccctgcgc cgtaagcgaa gtttgcgttg attgcaacta ggtcaccttc
    29041 atcattttgg tacgtagaag ctaaaagtga tgggtcgatc gtatggttga acttcaagtt
    29101 cttagggttt tcttcaatat catcgaatgt tgctgtttcc agatctactc catctttgac
    29161 tttgactaag ccagcatctt gtagaattgt gatgatgcgt ccccagtctg attcagaatt
    29221 tgaagtaatg attgttgcac catcttttaa ttcggaaaca tctttgactt ttttagagta
    29281 caagcccatt ggttcgatgt ggacagcacc ggcattgaca aagtcatatc ctttttcttt
    29341 gatttctttg ttcaaataag gaatatgctg gaagtaattg gcatcaatgt cgccttcttc
    29401 caaagattgg ttcggtaata catagtcatc gaatttgacg atttcaagat cgattccttc
    29461 atctttcaat aatggtttca catgttccaa aatctctgcg tgcggtgtcg gtgaagcgcc
    29521 gactttcaat gtcgtgtcgt ctgctttatt tgctgaatct ttgctgtcgc tgttgttacc
    29581 gcatgctgct aatcctacag tcagcaaaag cgctgctgca aatccaaaaa ttttcttttt
    29641 catatcctac atccccctat atcctattat cttttgtctg ttttcttagt taagaaatca
    29701 ccgattcctt gaacgataaa tacgattagt aaaataatta aagtcgcaac gaatgtcact
    29761 gttagattac cacgctggta gccttcctgc caagcaagac ctccaagtcc acctgcgccg
    29821 atcgcgccgg ccatcgcagt aaatccgatc atcgagatcg ttgtaactgt taatccagaa
    29881 atcaatgcgg gaatactttc aggtatcaag accttccaga tgatttccca gtaacttgct
    29941 cccattgcat ctgctgcttc cagtacacca gggctgactt cacgaaaagc aatctctact
    30001 agacgggcat aaaatggtgc tgcggataaa acaagagctg gaatggctgc ttgcgcacct
    30061 agcatagtgc ctacgattgc tttagtaaat ggaatgatca aaaccatcag gatcataaat
    30121 ggcgttgacc ggaaaatatt actgatgatc gatacgattc cataaatgat tcgagcatac
    30181 ggtttgtttt tgcgtccaat agagtaaagg atcaatccca aaactaatcc gatgatcgtc
    30241 actaagacca ttgagattaa tgtcatatat agtgtatcaa ggatagcctg attcatcgtt
    30301 tccgggttga tttgtttaaa atctagatat gtttctgaaa agcttttatc cacgatggat
    30361 cacctcaatt cctactcctt gttctttgat gaacacttct gcttgatcta attctttggt
    30421 ttcaccagtc atcaagacag tcaatgaacc aaaggaacct tctttcactt gtttgatctt
    30481 tccatacaca acgttgacat cgatgttata gcgtcgaatc gcttgggaaa tgactggctc
    30541 gttggcattt ctttcgctaa aggtcaaagt tgccaaacgg ccgcttggat tttctttgat
    30601 gagttcagct aatagttctg tcgaatcagc ttctggttcg atgtcttgtt gtacaaagcg
    30661 tttggttact tcttttttcg gttgtctgaa gacagtcaat acgtctcctt cttctacgac
    30721 tttccccaac tccatcacag cgactttgtt gcagattttg cggatcacat tcatttcatg
    30781 tgtgatcaag acgatggtca aattcaattt cttattgatc gctaacaata agtctaatac
    30841 ttcttctgtt gtttgcgggt ccaatgcgct agtagcctca tcacaaagca ggatctcagg
    30901 atcatttgcc aatgctcgtg cgataccgac gcgttgtttc tgtccgccgg aaagttgtga
    30961 aggatatgct tgtccgcgtc cttctaaccc gactaaacgc aacagttctt ctgcccgttc
    31021 tttacgtttg ctctttggta cgccagctaa ttccagcggc agctggatat tttcaagtac
    31081 agttcttgac cataacaggt tgaaatgctg gaagatcata ccgattttct ttcggaatgt
    31141 acgtaattct ttgtttttta attttgtaat atcttgatcg tttacgatca cttcgccgct
    31201 cgtgggaagc tcaagtccat tcaggagacg gactaatgta ctttttcctg cgccagaata
    31261 gccgacgatt ccataaatat cccctttttc aacgtttagt gaaacgtcat tgacggcttg
    31321 gatgtttccg tttttcccat tgaatgtctt tttgacattc gttagttgga ttaatgacat
    31381 gccattcaca tctttctctt ataatttttc aaacaaaaaa gccttcgccc tcttgcctta
    31441 agcaaaagga cgaaagcttg aacttccgtg ttaccacctt gatttaccgt tacttcgcaa
    31501 taacagcctc ttccagtact tggacttagc ttctttccgt atactgtcgc gctgtaacgg
    31561 gcactcccgt agtaagtttg cttacgctcg cttactctgc tctaagacca tcttccatct
    31621 cattttcgtt acccattttc agcaaacagg gctctcttca aacgtccgtg acatgtactc
    31681 ttcttttcaa agctttctcg tttcatatag gattgcttat gattatagca actggaagaa
    31741 tcagtgtcaa cttttttcaa gtgattttct gattttataa ttcgtcaaat tcttttggat
    31801 caacatcttt gaaacttaag atccacgcat tcatttcatc tgaatcattc aagatattga
    31861 tatcttcacc gattttatca ttaacagaag aaactgtacc cgttagcggg ctggcaaatt
    31921 cattgaccgc tttttccgct tcaacttcga tcagaggttc atcttttttt agcgattgtc
    31981 ctgcttttgg cagattggca aacgtgatgt ctccaagttc ttcttgcgct tcatttgtca
    32041 aaccaacaca gtattctttt ccattaaata agatccaaag gttgtccttt ttcttcaaat
    32101 gcttgcctgc cattttatat cagttctcct tcataaattt tttcattgaa tccaattgca
    32161 acaagctggt cctctcgtaa gatcagtggt cgcttgatca gcataccatc tgtcgataag
    32221 acttggctcg cttttgaagc cgtaaactcg cctacttgat ctttcagtcc aagttcccga
    32281 tatttcatcc cgcttgtgtt gaacaggcga cggattggta cttgactcgt ttctagccaa
    32341 gtctcaatcg ttgaggcctt cggtacttct ttgatcatat caacggtttg ataactaacg
    32401 ccatgctggt ctaaccacgc tttggctttt ttgcatgttg aacatttcgg gtaccagtaa
    32461 aaggtgtaca attttcttac ctccttgaag atcttgcagg tgcttcattt tggtatctca
    32521 tcgataatat caacccgata ccgatcatgt tccctaaaat cgaggatcct ccctgactaa
    32581 tgaaaggcaa tgggatccct gttaaaggaa gtaatccgat atttgctcca atattctcaa
    32641 agacatggaa cagcagcatc atgatcaaac cgcttgcgat ataggcgtaa aattcattat
    32701 tcgtatcgaa acacacccga atcatacgat agattaaaat aaaatacaag aaaatgacga
    32761 atgcaccacc gataaagccg aagttttcac cgataacggt aaaaatcata tcggactcac
    32821 gaacaggcac atagatattg cttacgttga atcctttacc aaacaagcca ccggtaccaa
    32881 ttgccaaaag tccttgggcc ggctgataac tcattcctga cgtatcatgg aaagggtcca
    32941 gccatgaatc aatacgtgca aactgataag atttgaatcc aactttataa agcaagtctc
    33001 ttccgccttc agtcgtaacc aagaagatcg ttcctgctcc aacgactact gccaagatta
    33061 ctacaggtgc gatgatgcgc caagagattc cagacatcag gaaaatcccg ccaaagatcg
    33121 caagaaagac aagcatcgtt ccaaagtcat cttgggccat gatcaatgct aaaaccggta
    33181 ttgtcacgat caagagcttc ccaatcagcc aaaagtccga tttcatcgtc cgttctttta
    33241 cttgcgtatt atgtttagtt acgatcagtg ccatcatcaa gatgtacgca atcttcatca
    33301 actctgctgg ctggaaagta aacgcaccga atcgaaacca gtttttagac cctgttgaag
    33361 cagctaaatt ctgatcatag aatttgagca agagtcccat taccactaac cccaaaccat
    33421 aaaggtaagg agtcagtttc cagatccatt tggaattcaa atgcatgatg acaacgattg
    33481 ctgccgctcc aactaaatac cagacaactt gcatccctac gcctttcaag actgctggat
    33541 tgttcggatc atggctaagt gctacatata atgagagcag accaatcaaa cataacagaa
    33601 agactggtaa aatcacgcca taatcaatac gattatcgtt cgaagctttt aatttttttt
    33661 ccatgtttca tcccttttct taaaaaccat actgctgatt attatagcgg tccagttaga
    33721 taatggaaag tctttccata gacatttggg aaaaattaac tttccgtttg tgcagttgct
    33781 tgagcaaatg cagtacaaaa gcctactgct tatctttagt gtatcataga actttttttg
    33841 atacatgcaa ttatctacca gctgagattc tcctcgctgt gagaagtttc tgtgctttca
    33901 ttgtatcgaa ggatctcttc ggcaatctct agcagctgat cagaaaccag attggttcgt
    33961 tggatgaaat aaaaatatcg atggaaattc aacggagtca ttggcacatt ttctggaaca
    34021 gagcgcttag acaaaatcga gcgaccgatt ccttccttca gcaacgcaac aattacatcg
    34081 ttacttttca cgatcatctt cttatcttgg atattcatct cttcaaaata acgctgcgtg
    34141 taatgaaaaa caccagagtt tgcttctctt acaagccaca atttgctttt tgggtcccca
    34201 gcgatgacta gctggtcttc catcaaagag tatctttgta cgccggaagt ctctaatggc
    34261 ttttcgataa aaccaaaatc ggattcatgt ttcgctactt gttctaatga ttcatgagaa
    34321 ttcgtgattt cgatctcaaa atgcacttta ggaaaccttt tgatcagatg tttcatcaac
    34381 tgaggcaaaa gatagacagc aaaggtgtgg gaagcaacga tccgacatac ttcttcttca
    34441 ttttgttcat tgagcaattt ttgctgagtt tcttcccatt cttctaacaa aaccagtgtc
    34501 cgttcatata ataagtcggc ttgcttagtt ggaagcatct cttttcttcc gttacgttga
    34561 aaaagatcga tattcaattc ccgctccaac tgtttgattt gattcgagac tgctggttga
    34621 gataaaaaca gtacttctgc tgctctggaa aaatttcttg tttcatatac tgctcgaaaa
    34681 gtcgttaata acttaaacat ggcaccactt ccataacttt ttatgataat tactataaaa
    34741 actatttgat ttaaatatac aaaaaaccat ctataataga aatgtacaac aaaacagttg
    34801 ctgatccaac tagtaactta gatgaagaca atcagctgtc tgcttgctcg taatcataca
    34861 ttcctattca ttttacaatg tattcgttca tcttggtact aaaatctatt aaataaaaag
    34921 gagaatatta tatatgaaga actttttgaa aattattccg atcccgatct gcgggttgat
    34981 ccttgggtta gcttcccttg gaaatctgtt taaagactat caccatgttg ctttaggcaa
    35041 tctaactggc ggtatctcta tgattcttat gatattcatt tttgttaaat tgtttatctt
    35101 attcgaacac acgaaacaaa cgttgcatga tccaatcatc gcctccgttt caccaacttt
    35161 tacgatgtca ctcatggtta tttgtactta ttttgtttca tatgaaagta ttgcaccaat
    35221 tgtcaaattc atttggctgt gcgctgttat cttccaagtg atccttgtct tttatttcaa
    35281 ttatcaccat gttatcaaag ctgatctttc aattgaagca atttatccaa gctggtttat
    35341 catttacgtt ggatttgggg tcatcactgt aactgccggg aacttcttcc cacttattgg
    35401 aaaaattttc ttttggattt cattgatctg ctatgcgttc ttattgccga tcatcatcaa
    35461 acgtgtcttt ttcgtaagaa atatggctca tccgacacgt ccgctgatta cgatcgttgc
    35521 agcacctggt tctctttgcc taacaggtta tcttaaaaac tttgctgaac ctaattttta
    35581 tcttgtcgta gcattgttcg ctttatctca agtattgtat ttcgttgtgc tgtctatgct
    35641 tccacgtttg ttcaagcttc gtttttatcc aagctatgca gcctttacat tcccgcttgt
    35701 tatctctgca acagctatat ttactactgt tcattacttc aacagtttag gtatctatag
    35761 tagcgtattg gatttcttaa aagttgcgga atgtctgttt gcaagtgtag ttgtcttcta
    35821 cgttcttgct cattacgtac gtttcttaat taaagaacat agcaaacatg gaaaatttgt
    35881 ttctaaaaaa atcgcttaat aatcgattca ataggttgtg aaaaagctgt tctgcatcaa
    35941 gtaataagaa cggccaaaca aaaacagctg ttcatgtttt tgtactggtt gggcttatta
    36001 ccgcagatgc aagcttttga acaccgttta ccaagaggtc gtaaaagaag tggtcagctt
    36061 caagaaataa gaaggaattt acgaaaattg cttctcaaat ttttgtgaaa tttcggctta
    36121 tttccgtaga agctacttct ggaacaccgt ttattcgaaa caagaggtcg tacaagactt
    36181 ttgtcacgac ctcttgttct tttgtcaaaa tactggttta gtgctactat gttcgagtat
    36241 gcttttagta tttattgacg aaaggaaccg atcaaatgaa atcattgtca catccaataa
    36301 aatctgtaaa ggattcagcg gtccgcgaaa tcttacccgg tttactgctt tcttttgcca
    36361 tcgctgcctt cagcaggctt cttgctattt atctgccaca gttaggtgga gcgactattg
    36421 ctattttatt gggtatttta ttaggaaata ctttttttaa acagcctgtt ctagcaatcg
    36481 gcacaaaatt tgctgaaagc aaactattag aattctctgt ttttttacta ggtgcaactg
    36541 tcacagctca aacgattgct caaattggtg taaaaggaat tgtttttgtg ttactgcaaa
    36601 tgtcagtcac tatcatcggt gcttacttga ttggtaaaaa actgcaattc agcgatactt
    36661 cttctttgat gatggctgga ggaaacgctg tttgtggttc ttctgctatt gcttcaatcg
    36721 ccccttccat ccatgcgaaa gaggaagaaa aaggacagat catcacacta gtcaatctac
    36781 tgggtactgt gatgatgttg actctccctt ttcttggatt acagttgttt ggtggaaatc
    36841 tcattgaaaa aagtgcactt ttgggtggta cactccaatc tgttggtcaa gtagtcgctg
    36901 gggcaagctt acttgacaat tctgttgtcg aattcgccat gctatttaag attctacgta
    36961 ttatgatgct cgttgttgtt gtctatctgt ttgaaaaatt catgcacaag aaacaaccag
    37021 ctctgtttga aacgccaact gatacgcaga aaaaacgaaa attaccgctt ccttggtatg
    37081 tattagggtt tgtgatcttt tgtttggtca acagcttgtt ttctttacct gtagttattg
    37141 accaatcggc acattttatc agcagctggt ttgagatcac tgctttagcg gcaattggtc
    37201 tgcgtttaga ctttgcaaaa ttcatgaaag aaggtacacg cttcttatct tatggattag
    37261 ctgtcgggct tctccaaaca gtgatggctt tactatttat ttggctgatc aaagtttaga
    37321 atgaacatga aaaaacagtt gtgattctcg catggaacaa tgtccgaatc acaactgttt
    37381 ttaattttgc agatatcctt ctaacaacaa caattggcgt ttgatttcaa ccccatctat
    37441 tgcgtttccc atatatcctg tcagttttcc attttgcccg atcactcgat gacaaggaat
    37501 aacgattggc aatggattgg ttcgatttgc ctgcccaatc gctcgcacag ctttcggact
    37561 atcaacagca acggctactt ctttatacgt tcggatttct ccataaggaa tggtcgacaa
    37621 agctttccag acattttgct gaaaaggcgt acctctcttt atagataaag gaacatcaaa
    37681 ttcttttctt tttcccgcaa aatattcttc aaactgttct tgtgtgcgcg ttaaaattcg
    37741 ctgattcgct gattcgcttt ctgaaattgg ctgaaaagat acagcagtca atccggattc
    37801 atctgcatct aaccataaaa agccgatagg tgtgtgtatt ttcattttgt ttgctcctag
    37861 tcaatagact ggaacttcct cctttttctc tatccaaaac tacttgccaa ctaataaaaa
    37921 ttgttcttaa aagtttgata aaccgaggaa acatggtaaa ctaaatacgt tagtttacaa
    37981 aaagaatacc tgttctttta cgtaaaatca aattttaaag gtgttattta aggtttatta
    38041 aattttgaat gtaaaccata tataaacata cgattgaaag gatagaaacg atgaaagtat
    38101 caattgttgt cccatgtttt aatgaagaaa aaactgttcc tctttttttt gatgaggttg
    38161 aaaaattcaa aggtgcccat gagttcgaat atttgtttat tgacgacgga tcaaaagacg
    38221 gtacgttagc agcaatcaag aagctagcct cagcttatcc ttatgtccgc tttgtctcat
    38281 tttccagaaa ttttgggaaa gaagcggctc tgtacgctgg attgcaagct tctacaggag
    38341 atttagtgac cgtgatggat gttgatctgc aagatccgcc cgaactgctt cctgagatga
    38401 tcaaccggat cactacttct gatatcgatt gtgtcggcac ccggcgttcg actcgtgaag
    38461 gcgagcctgc gatacgcagt ttctttgcga aaaaattcta ccagttgatc aataaaatca
    38521 gcgatacaga aatggtcgat ggcgctcgtg atttccgctt gatgactcgt caaatggtgg
    38581 atgccgtcct agaattaaca gaatacaacc gattttcaaa aggattattt agctgggtcg
    38641 gatttaaaac agaatatatt tcttatgaaa accgcgaacg tgtggctggc gaaacatctt
    38701 ggtccttctg gaaattattc aactactcga ttgatggtat cgtgaacttc tcggatgcac
    38761 cgttaacgat tgcttcattt atcggcgctt tgtcttgtgt cggttctggt attgcaattt
    38821 tgttcattat tttgcgggca ttgttgtttg gtgatcctac atcaggatgg ccttccatgg
    38881 tctcgatctt cctgttcatt ggtggaatcc aattgttatg tcttggaatc atcgggaaat
    38941 atattgggaa aatcttctta gaaacgaaac agcgtcctgt ttatatcata agagaaacag
    39001 aaaaagtgaa gccaaatgaa ttgaagcctc accaataata tacgtcaaat gaagtaaaca
    39061 tttttttaaa tgaaaaagga ctgtgacaaa agtcttgtca cagtcctttt ttccgaataa
    39121 atggtgttcc agaagtagct tcttcggaaa taagccgaaa tttcacaaaa atttgagaag
    39181 caattttcgt aaattccttc ttatttcttg aagctgacca cttctatcac aacctctttc
    39241 atatcttatt acttcttcat tgctgctttt agtgctgctg ctaatgggct ttcttctggt
    39301 tcttctgctt gtgcatattt tttcagcaag cgtcgttctt catgtttggt cattttcttc
    39361 ttctgctctt ttttatcaag caatttttct gtcgttccat cgtatttaca acggaaataa
    39421 gcaccgtttt taccttcgat gatttccatt ttccggtgac attgcgggca tcgatgatta
    39481 gagacttttg gatcttttct tctgcggtag ttgcaatctg aattggtgca gacatagatt
    39541 ttgccgtcac gtgtgttttt ctcgcgcaga ttggccccac attctgggca tttcttttgg
    39601 gtaatcgaga aatcttgata ttcttgtttg cttgatttga tctcattcac caagcgtttt
    39661 gtttcttttt cgattccatt caagaaggtt cctgcttgtt tctttcctgc agcaatagct
    39721 tcaaggtctt tttcccagct ttctgtcaaa tctggtgtta ctaaagaggg atttaccaat
    39781 actaataatt gcttaccttt aggagatact tgcagtcctt gaggggtacg ttccatcagt
    39841 tcagatttga ttagtttctc gataatctct gcacgcgtag ctggggttcc cagactgtat
    39901 ttttccattt gaccaagcaa gcttgcttct gacaatggtt taggcggtgc agatagttct
    39961 tttttgatgg cgaaatcggg attgattctc attccttttt cccatttgac tgtttccgtc
    40021 tcagtttcag tttcgccttt ccatcctgct tggacgacac gattttgccg aaaaatgaat
    40081 cgttctttac caaattcaac cgtaactttt gtttggctga ctttatgggg ttgagcaaac
    40141 agtcctaaaa aacgagagac aatcatttga tagatttttc gctcttcatt acttaatttt
    40201 tcataacgtg ctctgttttc agttggcaaa agtgcatggt gatcggtcac tttactgtct
    40261 tggaatactt ttgtctgttg gacgatggct ccgtttttca aatactgctt gacctcagga
    40321 gcaaagtcgc tgactgcttg caatcgttct ttcatcgtac ttttcatgtc atttgtcaga
    40381 tatttgctgt ctgtacgcgg ataagtaacg atcttatggg tctcatacaa actttgtaca
    40441 agacttaatg ttttctttgc agaatagcca tagcgttgat tggcttctct ttggatctct
    40501 gttaaatcat aaggcaatgg cgcagattcc gtttttaatt tttcttggac ttctgtgaca
    40561 gttcctttgc ttgtactgat caattgaaca agtttttgtg cttcttcttg tgtttttaaa
    40621 gcaaattgat ttttttgaag cattttggct tgttcttttc cagcttgcaa cgtgatcgtg
    40681 aaatacgttt gtggacggaa ctgctcgatt ttcttttctt ggtctctcac taatgctagt
    40741 gtcggtgtct gcacacggcc tgctgataaa ttatccgcgt acttcacagt taaggctctg
    40801 gtcacattca atcctaccag ccagtccgct tttgcccggg caagagcaga ttcatacaat
    40861 gcatcatatt ctttcgcagg tcttagttgc ttgaatccag ttttgattgc tttatctgtt
    40921 tgagaagaga tccataaccg cttcactggt ttattgaaat gcacatactc taagatccag
    40981 cgagcaacaa gttccccttc tcttccggca tctgtcgcaa tgactgcttc tgagacatct
    41041 tttcgctgag ccagctgctt gattgctttt aattgatgtc ctgttttagg aagtggtttg
    41101 attcctagtt ttttagggat cattggcaac gtgtccattt gccagctctg ccattcctta
    41161 ttcagatctt ccggcatttt caatcctaat aaatgaccaa gggcccaagt aacgatcacc
    41221 ttgggtcctt cataataatt tttgtgcttt tgattagcac caagcacctt gcttaggtct
    41281 ttcgcaacgc ttggtttttc cgctagaatt agttgtttca taaaattcct ttctgctttc
    41341 tactgtgatg ggctgatgat ttttcaacaa cgcaagtccc ttgtattgct gtaaatcatc
    41401 gtcacactct tcacaccagc gctcatctcc gtcattccaa aaggcgctga gaaagttact
    41461 ttttgcattg atatattcat aattttgatg gatttcgttc cattgttttt cgtacgcttg
    41521 tcgtgcttct tcgaaagact cgaatgtttc ttcttcttca atatcttctt cccagtcttc
    41581 aaaaaaccac caaggctcat tgtccccgaa catggtaatt acttgataca tactcgtgct
    41641 ccttctttca gcttttctag actcatctta gtcacttttc aagaaagttg caagaatttt
    41701 ctcttataaa agggtcattt aatgaacatc ttaaaattgt tacaaatgaa tctgattgtt
    41761 taaggcaaag tagcgataaa gttattgatc atccaaaaat agctgtcttc tggatcgatt
    41821 gttggttctt ttgtaaagta tcctaaaaaa cgtaaggaaa gataaccgtg gatcatacta
    41881 cgaagttccc tgcttcgatg aactttttct tctttcgtta attgaaaagc ctcaaatatc
    41941 tgcaaaatga tctgattcgt ttcatggatt ccatctaata aaacagcttc attggtatgc
    42001 ggtacactga tcagtaactc atacactgct tgatttgaaa aagcaaagga tcgataagtt
    42061 tctgcataga tctgcagtgc ttcctgacca ctttttccca caagagcccg tcgcagctgg
    42121 tcattaagtt cctgcagaag tttcgctgtt agcgctgttt tgacatcacg aatatttttg
    42181 aaatggttat acagcgaggg agccttgata tccaagcgtt tggctaaatg ctgaaaggtt
    42241 atttgctgaa catccatctc ttctgctagt tctcgaaagc agtcgatgat tttctcttga
    42301 gacagatttc tttttttcat ttccatgttt cctctcataa aataaatcct tcactctttc
    42361 agtttaccac gaaaaagaaa gagaaaaaag agactttcat tgataaacta catattgtag
    42421 tttataataa agagctgtag atgaaaattt tcagaaagaa ggagtctaat tggctgcaag
    42481 aataaaggaa aaattattta ggaaaagaga aacttgggaa caaaacttgt ttgtcttatg
    42541 gtttggaaca tttatggctg gtatcggatt tagtttagtc atgcctttta tgtcacttta
    42601 catagatacg ttaggtaatt atagtacgtc acaattgaac ttttggagcg gattgacttt
    42661 ttcatctact ttcttggtga ctacgcttat ctctccttgg tggggaaaat tagccgacca
    42721 aaaaggaaga aaattgatgc tgttgcgtgc ttcattagga atggcaatcg tcatttcttt
    42781 gatgggttgc gtgactagtg tgtatcaatt agtcgcattg cgtctgcttc aagggatttt
    42841 ttctggttat atcagtaatg ccactgccct tgtcgcaact gggacgccaa aagaaaaaag
    42901 tggtcaagtt cttggaacct tagcaactgg ttctgttaca ggaacattac ttggaccgct
    42961 tcttggcggg atctctgctt cagcgtttgg ctatcgccct acctttttca ttacagggat
    43021 catcttattt ttcgtcttct tgttgagtct gtttttcgtc catgaaaaat ttgtcccagt
    43081 gaaaaaagaa aacatggttt ctgccaaaca gattttcaaa gacttgaaat atccacacgt
    43141 cgtcatcggt atgttcgtca caacgatgat catccaagca tccaacaatt ccattagtcc
    43201 aatcatcagt ctgtacattc gccaattgct gcatggacat gggaatgtta cgttgatcag
    43261 cggaatcatt gcttcgatac ctgggattgc cactttgata gccgctccaa gatttggtcg
    43321 cttaggtgac aagattggga gtgaaagaat acttgcgatt ggtttgggtt ttgcgattct
    43381 ggtttatatc ccaatggcat tcgtcacgaa tgtttggcaa ttagctgcct tacgtttttt
    43441 gattggtatc tctgatgctt gtctgctccc tgctgtccaa gcattgatca caaaatattc
    43501 gcctcatcaa gctgctggac ggatcttcag ttataaccaa tctttccaag caactggtaa
    43561 cgtagtaggg cctatgatcg gctccagtgt ttccagtgca tttggttatc gcggcgtctt
    43621 tctttcgact tctcttcttg ttttggtcaa cttcttgctt gtacgacaca atacacaaga
    43681 gatccatcag caagaaactg cagaagaaaa agcttcagga gtctccatag cttcagggca
    43741 ctctccttct catagacaat aagcgtaaat gaaaaacact gcttgaacag ttgtcacaga
    43801 ctgtccttgc agtgtttttg tttaggcctg ttttttcaag aactcagata agaggaataa
    43861 tcccttttcc aaggtttctt ttttacaaca gtaacctagt cgggcatgct tcggtaaatc
    43921 aaaggcactt cctggtacta atagtactcc tgtttcttct aataaattga tacaaaatgt
    43981 ctggtcatct tcttcgatgg ctaatttaat gaaagaagta gagacgtaat tgggagcgac
    44041 aagttcaact ttcggttcat tggctaccca ttgttttaaa atcacaaggt tctctgtaat
    44101 gatctttttg tttcgcgcca atattttttc tttattcttc aatgcatgta cagcaagatc
    44161 atctgacagg actccgccgc aaatcatcgt gtagtctcga tactttcgaa aaacttctgc
    44221 caactcaggt ccagtagctg tccagccaat acgaatacct ggaatggagt aggttttgga
    44281 tagggaattg gttgctatac ctttttcata gacatctacg atcgacaaga attcaccttt
    44341 atccgttaaa ggcgcatata cttcatctat caatacatat gcatctactg tacgagcaat
    44401 ttctgcgatt ttttctaaag ttttccgatc tagcaatgtg cctgtaggat tgtttgcact
    44461 attcaaacag atgatttttg tttcaggttt gactaaggct tctagctgtt ctaaatcaaa
    44521 ctgccaatct tcttcttcct tcaaatgaac aaagtcaaca gcggcaccta aagatttggg
    44581 gatgtcatat aattgctgat aagtaggaag catcgaaaca acatggtctc ctgcttccac
    44641 taacgcgtat agagctaaaa gattagcacc agtcgctcca ttcgtttgta agatgttttc
    44701 cggatcgacg gtttgataaa gagaagcgac ttcttgtttg aaaacatctg atccttcgat
    44761 ccagccatag tccaatggtt cgtttttgcg tttttcgaaa aatttactta cgctagtccc
    44821 atctaagcca acgagttcgt ctaatgtcaa tgcttcgatc gagctttgtg caatatcata
    44881 taccgctttc ttttcccatt tatttagcca ttcttctaca ccgaaatttg cgattttcat
    44941 gtttctttcc cccttatatc ttgatccagc ctacagcaag caacccgatt gaaagcagtg
    45001 cggccacaca aatcagccca atcattactt tttcttttcc cgtaatttga tgtttggttt
    45061 cacgacaagc gatccagtag aagcaaaaac caggaagata ggcaatacta cataaaagga
    45121 cataagaaaa tcctgctaaa atgatgccca tcaattcaaa aactacagca atcccaccga
    45181 tcactacttg ttttttgatt ccttctttta aagaaaactg gacttgatag atcccgacaa
    45241 gtagataaca aatcaaaatt gccgctgtac ataaagaata ggcaaattga taggcataat
    45301 cagtaactaa gaaagtcaat aagaatagat tagtcaagat tgcagtaaca actaacgaat
    45361 aagttggggc atttttttta ttcgtttttc cccaaccttt cggcaacaga ccgtctcgag
    45421 ccatcaacat cgttgtttct gctgggagca tcgtccaaga caaccaagaa ccaatgatcg
    45481 aaataatcaa gccgatattg atcagcgctg ctccccaatt tcccacgatt ccttttaaaa
    45541 tatttgccat agcaggttgt gaaatagttg ctaactcttc ttgagataag acgccgtatg
    45601 gcaagatcga agcaaggata tagataaaca ataaacaaag cagaccaatg atcgatgctt
    45661 gctgggcttc tgaacgtttc ttcgcgcggt tggctaaaac acttgcgcct tcgatcccta
    45721 caaagaccca catcataacc atcaaacaac ctttaatctg caaccagatc gttccttgct
    45781 gccctgttcc attcactaga ttatcagata cgttacccca aaaatcagca gtgaatatat
    45841 tcactttaaa tgcgataaat acaaatatta aaaataggaa taatggcact aatttacaga
    45901 tcgtcacgat tgtattgatg acgctcgctc cttcaactcc attgtttact aataaagtca
    45961 gaccccaaat aaaaatactt gcaaataaaa tagaaggaac attttgtcca cctttgaata
    46021 tcgggaaaaa ttctcccatg gcgctcatca gcatcgttgc aaaagcaaca tttcccagcc
    46081 acgcagacaa ccagtaaccc caaccactga tgaagccacc taatttacca aatgaagctt
    46141 ccgcgtaacc gaaaatacca ccatctagat ctggacgctt ttctcctaaa tgattcagcg
    46201 ataataccaa agctaaaata ccaatcccaa cgattatcca tgaaaggatc gctggccctg
    46261 gagctgcaga actagccaga tcacttgtga tcccaaacac accgcttccg attgacgaac
    46321 tgacaaccag agcaaccagt ccccatttgc taatacccgt cgatttcttt tccatttcca
    46381 tcaccctcac ttataaaatt gaacaaatca cttgcaaaag attcccttct attttgcaac
    46441 tgctcttgct taacaaaaag caactttatt catattattg gatattatga actttttaca
    46501 caagtatttc aagtataaaa tgaataaaaa ttaattttat tgcaaaaaaa cagctatgct
    46561 atccaaaaga aaaggtgttt cttttgttag ccatagctgt tttgattcat ttaatatcgc
    46621 ttaaacgtat tgtaaaactt ttgtttcttg atatgcgtgg tcgatcaaac caccacccag
    46681 acattccatt ccatcataaa atacaactgc ttgtccagga gtgattgcac gtacaggttc
    46741 gtcgaatacg acttctgcac gattatcatc caataagcga actgtcacag gaacgtcttg
    46801 ctgacgataa cggaatttcg ctgtacactt gaattctttt ggcattggtt cattcgtcgt
    46861 aaagtggatt tcacttgcat ccaagcttgt ggcatacaat gcaggatgat ggaacccttg
    46921 ccccacatat aatgtgtttg tcgctagatc ttttcctaca acaaaccagg gttcttgcga
    46981 atctcctccg ccaccgatcc ctagtccttg acgttgacca atcgtataat acatcaagcc
    47041 agcatgttgt cctttgactt caccatcaag agtgaccata tttccttttt ttgctggcag
    47101 atagttgctc aaaaattgtt tgaagttctt ttcaccaata aagcagattc ccgttgaatc
    47161 ttttttctta gcagtcgcaa ggcctgcgcg ttcagcaatt gcccgtactt ctgatttttc
    47221 catgccgcct agagggaaca tcgtttttga aagctgttct tgtgataatt ggctaaggaa
    47281 gtaagtttga tctttattat tgtctactcc acgaagcatg tggaccacgc cgttttcatc
    47341 gcgagtgact tgcgcataat gtccagtagc tacataatcg gcgccaagat ccattgcata
    47401 atccaagaat gctttgaatt tgatttcttt gttgcacatc acgtctgggt taggtgtacg
    47461 tcctgcgcgg tattcggcta ggaaatattc aaatacacga tcccaatatt ctttttcaaa
    47521 attcacagag taataaggaa tcccgatttg agcagctact ttcgctacat ccttataatc
    47581 ttccgtggcc gtgcatacac cgttttcgtc cgtgtcatcc caatttttca tgaatattcc
    47641 gatcacgtcg tatccttgtt cctttaacaa aagtgctgtt acagatgagt cgacaccgcc
    47701 gctcatccct acgacaacgc gtgttttgct gttgtctgtc atgatatcac catcatttca
    47761 attagattct gaaacatcta cgagttgaag gtcgcaactt ttcagtattt tacattatac
    47821 gtcatatttc tgaaaatttc atcccttaat tatcaagtcg taaaaatact gttctactgg
    47881 acctattcag tacacaaaca tgatagtcaa ccaaaaaatc actcatcttt tgagcattcg
    47941 atataaaaaa ttggcatact cataaaaagg gccagccttt cggcaataag gaataatttt
    48001 ataaattgtg aaaaactatt tttcaaaatt gcttcttatc gcttaaagct gcacgtctca
    48061 tttacaacct tttcttttta gatgttatga gttgctcaga taagtgattt tgtttactct
    48121 aagaaaaaag ggaggcaaaa gatacatgaa ttactttatc agtgatatgc actttttcca
    48181 tgaacgctta ttaggaaaaa acgactttgc tccgcggctc tttgcaaatg tggatgaaat
    48241 gaaccaacag ttgatcacta gctggaatgc agtaataaaa gaaaccgacc atgtttatca
    48301 tctaggcgac cttgctatgc atccgcaata tgaaaaagca aatgcagaaa ttttggaact
    48361 ggtcactcaa ctgcaaggaa caatccactt gatcaaaggg aaccatgaca gtcgcgcttt
    48421 tttccgttat ttagaaaaaa atgatcctag gcttactgac ggaagtccca aattttattt
    48481 ttatgatgta ggtgccatcg ttaaattcga ccatcaacaa tattacttga ctcattatcc
    48541 gatgttgctc gggcctaacg acactatccg caatcttcat ggacatatcc atcattacag
    48601 cgtacctatc gagaacgatg tcaatgtagg cgtagacgca ccggaaagag aactcttaaa
    48661 ggaaaaacta ccatttggca ctccgttatc tgagcaacaa atcaaagaaa tctatgaagc
    48721 aaagaggaag tacgataggt cgtgaaaaaa ctgccctata tcaagtatta aacaaataaa
    48781 gataattact catatttttc atttgagtag gcttattgcc acaggaacat taggatcaga
    48841 aatggagttg taacaagact tctgtcacaa ctccattcca tactattcgt ctttttgctc
    48901 atggtgttct tttaccagtt ttttctgtaa ttctttatca taatttcggg cagctgacgt
    48961 taaaaataaa acgattccgc ataataaaat cccgattccg gaaaacaaga acattttttc
    49021 tacccctaaa cgatcagcta atggtcctgc aaataataat ccaattggac ctgccaggtt
    49081 catcaaagag ttgaagttcc ctaagacacg acctaaaaca ttcgattcat aactctgctg
    49141 gatcattgcc atcagcagtg tattgaaata tggcgttgca caacctgctc ctgcattcaa
    49201 gataagaaag tacaagaacc cttgactatc gtttggaacc aatccgcttg caccgatcgt
    49261 caggcccata atgatgtagg ctataataat aggtttcatt cggtctttcc atgttcctat
    49321 aaaactgatc agtgcaccgc ctaagagcat tccgactgcg tagactactt ccactgctcc
    49381 cgcctgtcca acggaaccac caaagtaatc tagcgtcatc aatggataca gactgattgc
    49441 tggcatgaac aacagcatca caaatgcacc attgatcgtt atgtaccata accctttatt
    49501 atccatcaat tgctgcagcc caaattttgc atctttaaaa atagtaagcg gaacttccaa
    49561 tatttcagga gaaacttttg ggatcttcac aaaaatcaat aagccgacac caaaaactgc
    49621 ccccaataca tctaataaaa taaggtaatt gacaggaacg actgaaaaca aagccgcacc
    49681 tagagctggc gcaatgatga aattcgctga ttggaccatt cctaactgtc cattcgtcct
    49741 tgttatgtga gaagatggaa cgattgtcgg cataatcgac tggatcgttg gcatttggaa
    49801 tgtttgtgcg accgaacgca taaacaaaga cacaaaaact agccaaatcg ggaaggattc
    49861 tgaaatcgtt ccgactactg ctaaaataag cgcgaaaatc gctacaataa tatccgtgac
    49921 aatcaaaaga gcttttttat cccagcgatc cactagcggt cctacaaatg ggcttagtaa
    49981 aaccatggga atcattccta gtaaagtagc aaaactcaaa attgtcgccg aaccggtttc
    50041 tcttgtcaaa taccagatga tcgcatattg gacgaccata ctagtgattc ctgacaaaaa
    50101 ctgtcccgat aaaaagaaca aataatttct cttccaattc gttaaaacga ccgactgttc
    50161 attttccata aacatccctc ttttcttttt cattttgtat agcgtttgca caacaatcat
    50221 tatacgggat tcttttttca aaaaatacct ttttccctaa ataacaatcg tttcaattta
    50281 aatttcttta cttagaaaca ataaatcagc aaaatattaa aaataacaac atgtgttaaa
    50341 tttaaaaata aaaaagacaa ctaatttgcg tcgtccttac aaagttagtc atctaacaat
    50401 aggccgtttc aaaactagtt gtctttttat atccacagat cattcgactt tttcgaataa
    50461 cccacggcta atcatcccat ccatcagaaa ataaaattta tcttggctca ttttctgttt
    50521 tggatctttg aaaatattga ctgctttcaa tccatttgct gtagtgatcg acattttcaa
    50581 tgtttgaata tcttttgata cagtgatttt taatttgaat ccttctttgc tttgcggcgt
    50641 ggcatctaat ggtcggatca attgataatt gcctccgttt gtttctgtaa atccattatc
    50701 gcgcaatgta tatctttttg catcaggatg caaacgatag ctaattggtg cgcccagtac
    50761 cgttgctgtt gtttcaaatg ccatgatttt cacctcgata aaattagttt ctctttatta
    50821 taaaagttta tcctgatttt tactaggttt ttcagttaag ttccctaaaa aatgaaggcg
    50881 ttctctcaga catctgttca tataagaatg acttcactag ttattttttg acagcacgaa
    50941 ctaattgatc aaggaaatac tggatgtcgt cttcggtatt tcccaaacca aagctgatac
    51001 ggatggattc ttttagtatc ggtgtatctt ctccatacat tgcttctaat acgtgtgaag
    51061 gctcgatatt tcctgctgta caagctgaac cagtagaaat agcgacccca ttaagatcaa
    51121 gcttcatcag tagcaaatca tttgcttcgc caattaagcg aagattcaac acatgaggga
    51181 gtttattcgt taaatcacca tttacttgat aagggatttc gtttgcttct aatgtatcaa
    51241 gaatcaattg ctggaatcct ttatatttgt tgttacgtgc ttcacgttct tcaggtgaca
    51301 gcagttcaac tgcttttgcc ataccccaga tccctgctaa attttctgta cctgcacgcc
    51361 gcttttcttc ctgctccccg cctaaaagca atgcagggat atttactccg tctcgtttat
    51421 ataagaaacc gacgcctttt ggcccattga ttttatgagc agagatactt aataaatcga
    51481 ttcctaattc ttctggatgg atcgtttggt ttccgtacgc ttgtaccgca tctgtatgga
    51541 aataagctgg atgatccgct aaaagttcac cgatttcttt gattggcatc aaatttccga
    51601 tttcattgtt cccgtacatc acagagacca agatcgtatc ttctcgtaac gcttttttga
    51661 cctcttcgat cgacagattc cctttttcat ctacaggcag atatgtaacg tcaaacccct
    51721 ttgtctctaa atatttcatg gtattaagaa cagcaggatg ttcgatagct gtagtgatta
    51781 gatgtctgcc ttctttttga cgcgagaacg ctgtttctaa gatagctgta ttatcccctt
    51841 ctgttccccc actgttaaag atgatctcgt gaggttttgc ttgcagactg tctgcaatga
    51901 tttgtcttgc tgtttccaat ttttcatgcg cgtggcgacc aaatccatgt atgcttgaag
    51961 gatttccaaa cgtgtcttgc atgattgccg tcatcgcttc aattacttgt ggatgcatgg
    52021 gggtagttgc cgcatgatcc agataaatag ttttcacttc attcatccct tccaaattat
    52081 tgctaggcac attctagcat aaaatagcga acaaaccaaa gaagagctca tttttgtcta
    52141 gaggacgttt catgggcata gaaaaaagga gctgtgacaa aagtcttgtc gcagctcctt
    52201 gaagctgctc acttctgtca caacttcttt ccctcttttt tttgtttatt cgaattcttt
    52261 ttcttccaga cggaataacg gactcatcgg tgtattttca tggatgcgtt tgaccgcttc
    52321 acccattaat tctgaacatg taacgattgt taagttttct ggatgacgat tttcttctgt
    52381 gaaaacagaa tcagtgatac aaatatcttt gattggtgca ttgtctaaaa tacttttcgc
    52441 atgatcggac aataatccat gtgacgcaca ggcatatact tcttttgcgc cgttttcttt
    52501 taatacattt gctgctcgtg caagcgttgc tcctgtgttc aagatatcat ctaccatgat
    52561 acatgtcttt ccttgaacat caccgatcac ataaccaccc tcagttgaag catcatctgc
    52621 atgatctacg atggctaatg tgctgttcaa atattctgaa agactacgtg cacgctgaac
    52681 accgctgttt tttggcgaaa caactacgat gtcatctccc gtcagaccta attgacggta
    52741 ataatgagca aacaacggca tcgtaaataa attatctaca ggaatatcaa agaatccttg
    52801 tacttgaacc gtgtgcagat ctaaagtcag tactcgagtt gcccctgctt cttcgatcaa
    52861 gttagcgatc aatttcgcag tgatcggttc atgaggtttc gccgtgcggt cttgcctagc
    52921 atacccatag taaggcaata cgacattgat cgttttcgca cttgctcgct tcattgcatc
    52981 gatcatgatc agtagttcca tatagtaatc attgacaggt gcattcgttg attgaacgat
    53041 atacacatga tcccctcgaa tactttcttc gatattgatg gaaatctcgc catcactaaa
    53101 ttgcttcacg acgcttttac ctaattctgt tccgaacact ttcgcgattt tttcagctaa
    53161 tggacggttg ccattcaaac taaaaatctt caacgtgtca tcctgatact tattactcat
    53221 gtagtcctcc ccaaaacttc tctattcttc gatagtttaa catatttttc caagattttc
    53281 tgttaatttc agcaaattct taaggaagtg aaactgttcc gttactccaa ctggcaggaa
    53341 tgactttatg ataatcgccc cagttgtcgt gtactttgta ataacgttct cctgtttcag
    53401 tttcaaaata agcgtacgct gtcacccaat gattgccata tgtactgcca agtactttca
    53461 aaataccaat catcacaggt ttgccttcac gtatacgttt tgtagctcgc tgccatgaac
    53521 ctagaagagt tgctcgtgca cgctcatgat tgccattctt ctttaaaaaa ctagaaatcc
    53581 ctgtactaac ctgaaaagga atcgtaggaa gtcctagtgg ttggatctgg ctacgcaatg
    53641 ccttcgtcaa aaccaacgaa tcagccgtat ttttcttgcg aatctcattt ggaagcatcc
    53701 accccttacg atagtcttga taataggcaa ggagaactgc tgccgcgtaa gtaccacaaa
    53761 gatagcctga gggggtagcc catttcttat acctcaaaaa acgttcttct ggcaatccca
    53821 cccagcaatt tgcgagttcc tttcctgacc ttttttcttc gatcaaaacg ggaatatctt
    53881 cttttctgtt gatccatcta gataactcga ttggctcttc attgatcagc ttccattttt
    53941 tacaagaaag accctcttga taagtatatt ttgctggaga atattctacc ggatgtcctg
    54001 attgatcgat aatcacataa ctttgatctt caaaaaccag agctaaaaaa agcaatttac
    54061 tttttcttga ctgcagctgc tgagtgctgg ctaatttttt aattttttta tctactttga
    54121 aatataaagg tttatccact acttgattca gttgggatcg cctccttttt ttcattataa
    54181 gtgaaggatt gaaaaaaaca aatcagtttg attgttcgaa ttttcaattt tttatgttct
    54241 atttgttaat tccttcattt tgtaagataa tgggcacacg aaacaaaaaa ggagcgatcg
    54301 atgaatgaac aaagaacgat tgaaacaaga tttctatgaa gcagtcaatg aagaatggca
    54361 aaaaacagca aaaatccctg cagataaacc agctacaggc ggtttccaag atttagttga
    54421 cgggatcgac caacttttga tgggagaaac agacgatctg cttgcccatc cagaaaaagt
    54481 gtcttcagaa aaaatgaaac atttccttgc atattatcaa ctggcaaacg attatgaccg
    54541 aagaaatgag ttgcatgctc aaccgcttca acctataatc gaaaaagttg aatcattgca
    54601 gtctttcgac gaattgaata agcaatttcc agaatggctg ttggatacat taccattgcc
    54661 atttaatctg gatgtagatg cagatatgaa gaatgcgcaa acgaacgcct tctttgctta
    54721 tccgccttct ttattccttc cagataagac gtattatgca tcagaccatc ccaacggtgc
    54781 acaactaata ggcgttttct ttgatatggc tgttcagtta ttagagcttg ccggcaaaga
    54841 aaaaagtcag gcagaagcaa tcacggaaca agcagtgcaa tttgataaat tgattgctcc
    54901 tcatgtaaaa agtgcagaag aaaacgcaga ttacagcaaa atgtataatc cgcaatcttt
    54961 tgatacattt attaaataca cagataaact ggacttgaaa aaacttgtca cgggtttgat
    55021 tgggacaact ccagataaag tgatcgtaac tgatccagtg tacttcgatc atttgaatga
    55081 catcctgaca gaagctcatt ttccgttatt caaaagctgg atgatcatta aaacagtacg
    55141 ttctcttagt ggttatctat cagaagaatt ccgccaagtc agcggaatct attctcgcgt
    55201 attgtctgga acagacgaag caatgcctca gaaaaaagca gcgtattacc ttgcctctgg
    55261 acaattcgat caagtagttg gcgattacta cggaaaaaaa tattttggcg aagctgctaa
    55321 aaaagacgta gaacaaatgg tgaaaaaaat gatcgccgtt tataaaaaac gtctagaaga
    55381 aaatgactgg cttggggatg caacaaaaga aaaagccgtc ataaaattaa ataacttagg
    55441 tatccaagta ggctaccccg ataagatccc agcattattc gaccagttca aaacagtacc
    55501 tgcagatcag ggtggtactt tgctttcaaa tactcttgtt ttcagcaaac tcacattaaa
    55561 agatcgtttc agcaaatgga acaaaccagt ggatcgttca gaatgggaaa tgagtgctga
    55621 cacggtcaat gcttattatc atccatttcg gaatgtgatc gtctttccgg cagcgatcct
    55681 tcaagcacca ttttacagtc tagaacaatc aagctctgct aattatggtg gaatcggagc
    55741 tgttatcgct catgagattt cccatgcatt tgataataac ggcgctttat ttgacgaata
    55801 tggcaacttg aacaactggt ggacagaaga agatcttaca caatttcaaa acaaagcaca
    55861 agcaatgatc gaagaattcg atggtctgcc ttttgctgac ggaaaagtaa acggaaaatt
    55921 aaccgtttcg gaaaatattg ctgatgcagg cggtctaagc tgtgcattgg aagcagcaaa
    55981 aacggaatca gatctttcta tcgaggaatt ctttgtcaat tgggcaacga tttggcgtac
    56041 aaaagcaaaa aaagaatacc aacaactttt actgcaaatc gatgtccatg cccctgctaa
    56101 actccgagca aacgtgcaac caaaaaacct tgacgaattc tatgaaacat ttggtatcac
    56161 ggaacaagac gctatgtatc tagcgccaga aaaaagagtg cgaatctggt aagaggttgt
    56221 gccagaagtg gtcagcttca agaaataaga aggaatttgg gaaaatcgct tctcaaattt
    56281 ttgtgacatt tcggcttatt tttcgaagaa gttacttctg gaataccatg tattagaggt
    56341 tgtgaaaaag ctgcttagtt tcaagtagta agaaaaattt tgtgaaaatg gctttccaca
    56401 tttttgcata aatttgactt actaccgaga aactggcttt tgaacaccgt ttatcgagag
    56461 gttgtgaaat cagcgtcctg acctgagtat tagagaaaaa aacggaaaaa tagttcctca
    56521 tattttgccg tttgttgagc taataccgag ggtcagctga ttgaacaccg tttagtggag
    56581 agattgtgaa aaagctgtcc tgcatcaagt aataagaaca gccaatcaaa agcagcaagg
    56641 agaacctcat ctataaaaag atagaaggaa gtgagacatc tattggtctc atttccttct
    56701 atttttactt tcctcagtca attgttttac atcataaaag gagaaattcc acttattttt
    56761 ttcgctgttt catgacataa acaactacac cgattaacaa aattcctcca gctaatgcta
    56821 gcaacgggtt attaaattct cccgtttttg ggagtccttg agtgccattt ttttcacttt
    56881 cttttgctgt cctatccgga tgagaaggtt ttccatttgg ttttccattt ggtgattcat
    56941 ttcctggatt ttctctttct ggtttgtcat ttcccggggg cacatcggca gtttctcgca
    57001 cagtgatcgc tttttgctgg gtaacagatt ctgtatgagc agaccatttt tccccatcaa
    57061 atatttccga acgataagtg acttctagcg tatattctcc ttttgaaggt gctgaaaaaa
    57121 tagcggtatg attagaaaat tgagcacttg actgtgtttc aacgatttgg atcttttctg
    57181 ggaaataacg catatcttca aagacaggcg ttccttgatt tggtgtgaaa gttgacacaa
    57241 aaactgtaaa aggcttcagt tcaatgatat ttccttctgc attctccgcc acaccatttg
    57301 cttcttgtat aataatcgga ttattttgtt catttggttt tgtctgattt ggttcttgta
    57361 cgattgcata ctctggatat tccgaagacg gtgaggtttc tccgtcaaaa atagcaccta
    57421 cagataatgg aagaccatcc actctttcct tttctgtttg acgattcccc ggtttaatct
    57481 gcatcagtcc atgaacatgg atacttccat tttcatagcg cgtaacaggc tgctgacctt
    57541 ctttcgaaca tgtatttaga gactcgatcc aatcttttga tatggtatgt ccaagagtat
    57601 tttctgattg tttctctcgt tcattccaat agtagttcaa cgagtggtag atttgatctt
    57661 cgttttgatt caatgggcgg atctgctctc tcatctcaag attctctgtt cggaaagata
    57721 agataccaga agcatggtag tctgtgtttc ctgctgaaga ggtataaaga gccacattat
    57781 atgaaccgtt attaaaactt gtactgctat tgacgataat atctgttccg ctattggaat
    57841 cgattccttt cgcaagattt tcgaaagaca aactattgat caattcatga gggcccgtta
    57901 aagaagaacc gcccattttg aatccattac cgttaccttc tccctcaatt cctggtaccc
    57961 agccgtttcg ataagcaact gagtttttga tgattacttt tccgatcgaa cctgtttcat
    58021 ttttagcaaa aaggtcccaa ccgtcatctg cattatgata cgcgatacaa ccgtcaaata
    58081 catttccttc tcctattgtc agtttggccg caaatccatc ggcatcttca aatcctggat
    58141 cggcattttc aaaagatgta cagttcttga ctaagttatg cgcgggccat gcttcgaaag
    58201 gatcatttga gctaccgctg atttggattc ctgtatttcc attccgataa gcatgaatct
    58261 cttcgatcaa attatgattt ccagaaatct gtaatccttt ttgcatagct gcactatttg
    58321 taatgtcaaa ccctcgtaaa ccccagtagt gactgaacag tgtcatccca tttccagttc
    58381 ctttaaaatc aagtacagga cgcttgtttt ctggattttt ctctgcaatc aactgaatcg
    58441 ggttttctct tgtcccgtta acgccttttg gaatcgtcaa tcctctttcg aaggaataag
    58501 ttccaggcgc catgacgatt gtctgcccag catatgcgta tctcaatgct tgtgtcagag
    58561 ataatggatt ttgtctgctt ccgtttcctg catctgaccc ttctggtgtt acataaactg
    58621 tcgaatattt aggtttacgg tagtccactg tatgaagaat ctcttttgtt tcataactag
    58681 tcatctctac gtattcttct ggcggatagt ttttatctgg cgtaaaactg aaagtaaatt
    58741 cgttcgttcc ttccatcagt tttgtctgat aatcaaattc ccgattcgca gtgatagcca
    58801 agttttttgc gttcttaagc acctctcctg ttgctttatt tttaattgtc aataatccgt
    58861 cagcatttgc tctaaaggac atagtatgat cttggtttcc tgaatgatta ctagaggtca
    58921 cagtgtaaat cggatcaatc aagcgagtag gtctttcttg cccaggagga tctgtcgcag
    58981 gatctgagta agcaacttcg attccttcta ccttgatcgt catattcctt gctgcagcaa
    59041 atcctgcata aataaccgat tcatctgaag cgtataattt ttcccagtca tacatgatgt
    59101 cagaagccat ttcttctcct gtttcaggat cgtaataata tgcctctaaa ccagtattcg
    59161 tttttttcat ctctacgtcc agtttagtaa tcgagttcgt ggccggaaac agattcccat
    59221 gaccgtttcc gaatatatta taagaacctg tttctttttc caagaaccct gctgaagtct
    59281 ctaaaggtgt tgtttccact gagacactcc caggagctgg cgcagcttgc ggatcttcag
    59341 atgatattcc tgtgattgcc cgtgtcccca atccaagtcg catcgtatat ttgctgccgc
    59401 tcgtgttgac cacttcttgt ctatccgagt cccagacata ttcgatccga ctgcctagta
    59461 tggcaaatga atttgaataa aatgcctgcc caaacaaatg attttttggt actgcgtctc
    59521 ttaccattaa agcaaatcct tcttgggcat tcgtataggt ccaagattct atttcgatcg
    59581 tcgcccgcat cctaaagttg atgtctttgg ggattgcttg ataataatag gtcattccat
    59641 ctgatccgct tgactggaat tttccgccgt tattcgtgga agagagccgc acgccgtctt
    59701 ctaatggttc aatggcatac ctactagcac ttgtgctttc tccgaaaaca acccctttcc
    59761 actcttcatt tgcttcttca gattgctttt ttgtcttttc attttctgat tctttcatca
    59821 taggatcatt tccttcttcc gtatccatat cttcactagt tcttggtatt tcctccattg
    59881 ttgacatccc ttcaatgttc acgtgtgcat tttcttcgtt cacagactgt tgttcgttag
    59941 cagcaacttc aacgacagaa attaaaaccg gggtactgag cataaggaga ttcatcatta
    60001 gcgcactgta ttttatacgt ttttttaaca agtgtattcc tcccgtaaca aattagaaag
    60061 cgtttactta aagtattacc taatttattt ttactgtcaa taaaaaacaa aattataata
    60121 agtgtatttt ataaaaagaa aaaatataac
//
LOCUS       DAZUJR010000006        59296 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.006, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000006 DAZUJR010000000
VERSION     DAZUJR010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59296
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.006"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            18..536
                     /locus_tag="ACG804_000340"
     CDS             18..536
                     /locus_tag="ACG804_000340"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFS4831301.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            664..1347
                     /locus_tag="ACG804_000341"
     CDS             664..1347
                     /locus_tag="ACG804_000341"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HFS4831302.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1656..1729
                     /locus_tag="ACG804_000342"
     tRNA            1656..1729
                     /locus_tag="ACG804_000342"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1690..1692,aa:Arg,seq:tct)
     gene            1888..2247
                     /locus_tag="ACG804_000343"
     CDS             1888..2247
                     /locus_tag="ACG804_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HFS4831303.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            2370..4001
                     /locus_tag="ACG804_000344"
     CDS             2370..4001
                     /locus_tag="ACG804_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015103 - inorganic anion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HFS4831304.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(4063..4704)
                     /locus_tag="ACG804_000345"
     CDS             complement(4063..4704)
                     /locus_tag="ACG804_000345"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFS4831305.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    4890..4966
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            4986..5294
                     /gene="rplU"
                     /locus_tag="ACG804_000346"
     CDS             4986..5294
                     /gene="rplU"
                     /locus_tag="ACG804_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HFS4831306.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            5321..5665
                     /locus_tag="ACG804_000347"
     CDS             5321..5665
                     /locus_tag="ACG804_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HFS4831307.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            5678..5971
                     /gene="rpmA"
                     /locus_tag="ACG804_000348"
     CDS             5678..5971
                     /gene="rpmA"
                     /locus_tag="ACG804_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HFS4831308.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            6405..9212
                     /locus_tag="ACG804_000349"
     CDS             6405..9212
                     /locus_tag="ACG804_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFS4831309.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            9403..9894
                     /locus_tag="ACG804_000350"
     CDS             9403..9894
                     /locus_tag="ACG804_000350"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HFS4831310.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            9997..10986
                     /locus_tag="ACG804_000351"
     CDS             9997..10986
                     /locus_tag="ACG804_000351"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HFS4831311.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            11019..11822
                     /locus_tag="ACG804_000352"
     CDS             11019..11822
                     /locus_tag="ACG804_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HFS4831312.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            11843..12757
                     /locus_tag="ACG804_000353"
     CDS             11843..12757
                     /locus_tag="ACG804_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFS4831313.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            12840..13214
                     /locus_tag="ACG804_000354"
     CDS             12840..13214
                     /locus_tag="ACG804_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HFS4831314.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGNNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            13353..13598
                     /locus_tag="ACG804_000355"
     CDS             13353..13598
                     /locus_tag="ACG804_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFS4831315.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            13770..14834
                     /locus_tag="ACG804_000356"
     CDS             13770..14834
                     /locus_tag="ACG804_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HFS4831316.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            15080..15505
                     /locus_tag="ACG804_000357"
     CDS             15080..15505
                     /locus_tag="ACG804_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFS4831317.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            15498..15947
                     /gene="nusB"
                     /locus_tag="ACG804_000358"
     CDS             15498..15947
                     /gene="nusB"
                     /locus_tag="ACG804_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HFS4831318.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            16044..16898
                     /locus_tag="ACG804_000359"
     CDS             16044..16898
                     /locus_tag="ACG804_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HFS4831319.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            16899..18236
                     /gene="xseA"
                     /locus_tag="ACG804_000360"
     CDS             16899..18236
                     /gene="xseA"
                     /locus_tag="ACG804_000360"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HFS4831320.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            18241..18465
                     /locus_tag="ACG804_000361"
     CDS             18241..18465
                     /locus_tag="ACG804_000361"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HFS4831321.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            18467..19357
                     /locus_tag="ACG804_000362"
     CDS             18467..19357
                     /locus_tag="ACG804_000362"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HFS4831322.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            19366..20184
                     /locus_tag="ACG804_000363"
     CDS             19366..20184
                     /locus_tag="ACG804_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HFS4831323.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            20291..20740
                     /locus_tag="ACG804_000364"
     CDS             20291..20740
                     /locus_tag="ACG804_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFS4831324.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            20758..22440
                     /gene="recN"
                     /locus_tag="ACG804_000365"
     CDS             20758..22440
                     /gene="recN"
                     /locus_tag="ACG804_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HFS4831325.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(22495..22611)
                     /locus_tag="ACG804_000366"
     CDS             complement(22495..22611)
                     /locus_tag="ACG804_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HFS4831326.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(22684..23640)
                     /locus_tag="ACG804_000367"
     CDS             complement(22684..23640)
                     /locus_tag="ACG804_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFS4831327.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            23811..24183
                     /locus_tag="ACG804_000368"
                     /pseudo
     CDS             23811..24183
                     /locus_tag="ACG804_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
     gene            24353..24784
                     /gene="mraZ"
                     /locus_tag="ACG804_000369"
     CDS             24353..24784
                     /gene="mraZ"
                     /locus_tag="ACG804_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HFS4831328.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            24805..25764
                     /gene="rsmH"
                     /locus_tag="ACG804_000370"
     CDS             24805..25764
                     /gene="rsmH"
                     /locus_tag="ACG804_000370"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HFS4831329.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            25769..26170
                     /gene="ftsL"
                     /locus_tag="ACG804_000371"
     CDS             25769..26170
                     /gene="ftsL"
                     /locus_tag="ACG804_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HFS4831330.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            26171..28363
                     /locus_tag="ACG804_000372"
     CDS             26171..28363
                     /locus_tag="ACG804_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HFS4831331.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKNGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            28389..29351
                     /gene="mraY"
                     /locus_tag="ACG804_000373"
     CDS             28389..29351
                     /gene="mraY"
                     /locus_tag="ACG804_000373"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HFS4831332.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            29365..30726
                     /gene="murD"
                     /locus_tag="ACG804_000374"
     CDS             29365..30726
                     /gene="murD"
                     /locus_tag="ACG804_000374"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HFS4831333.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            30752..31840
                     /gene="murG"
                     /locus_tag="ACG804_000375"
     CDS             30752..31840
                     /gene="murG"
                     /locus_tag="ACG804_000375"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HFS4831334.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            31855..33075
                     /locus_tag="ACG804_000376"
     CDS             31855..33075
                     /locus_tag="ACG804_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HFS4831335.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            33231..34556
                     /gene="ftsA"
                     /locus_tag="ACG804_000377"
     CDS             33231..34556
                     /gene="ftsA"
                     /locus_tag="ACG804_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HFS4831336.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            34579..35820
                     /gene="ftsZ"
                     /locus_tag="ACG804_000378"
     CDS             34579..35820
                     /gene="ftsZ"
                     /locus_tag="ACG804_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HFS4831337.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            35837..36514
                     /locus_tag="ACG804_000379"
     CDS             35837..36514
                     /locus_tag="ACG804_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HFS4831338.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            36528..37127
                     /locus_tag="ACG804_000380"
     CDS             36528..37127
                     /locus_tag="ACG804_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HFS4831339.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            37208..37429
                     /locus_tag="ACG804_000381"
     CDS             37208..37429
                     /locus_tag="ACG804_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HFS4831340.1"
                     /translation="MVYALLSWFPGGYQSGLGRLLAKICEPYISLFDRLPLRIGPLDF
                     TILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            37478..38260
                     /locus_tag="ACG804_000382"
     CDS             37478..38260
                     /locus_tag="ACG804_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HFS4831341.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            38281..38988
                     /locus_tag="ACG804_000383"
     CDS             38281..38988
                     /locus_tag="ACG804_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HFS4831342.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            39250..42048
                     /gene="ileS"
                     /locus_tag="ACG804_000384"
     CDS             39250..42048
                     /gene="ileS"
                     /locus_tag="ACG804_000384"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HFS4831343.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(42097..43623)
                     /gene="zwf"
                     /locus_tag="ACG804_000385"
     CDS             complement(42097..43623)
                     /gene="zwf"
                     /locus_tag="ACG804_000385"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HFS4831344.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(43638..44285)
                     /locus_tag="ACG804_000386"
     CDS             complement(43638..44285)
                     /locus_tag="ACG804_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HFS4831345.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(44469..44798)
                     /locus_tag="ACG804_000387"
     CDS             complement(44469..44798)
                     /locus_tag="ACG804_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HFS4831346.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            44975..45703
                     /gene="sfsA"
                     /locus_tag="ACG804_000388"
     CDS             44975..45703
                     /gene="sfsA"
                     /locus_tag="ACG804_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HFS4831347.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            45719..46732
                     /locus_tag="ACG804_000389"
     CDS             45719..46732
                     /locus_tag="ACG804_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFS4831348.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            46732..48009
                     /locus_tag="ACG804_000390"
     CDS             46732..48009
                     /locus_tag="ACG804_000390"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFS4831349.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            48072..50774
                     /locus_tag="ACG804_000391"
     CDS             48072..50774
                     /locus_tag="ACG804_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFS4831350.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            50926..51243
                     /locus_tag="ACG804_000392"
     CDS             50926..51243
                     /locus_tag="ACG804_000392"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFS4831351.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            51273..51593
                     /locus_tag="ACG804_000393"
     CDS             51273..51593
                     /locus_tag="ACG804_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFS4831352.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            51701..53161
                     /locus_tag="ACG804_000394"
     CDS             51701..53161
                     /locus_tag="ACG804_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFS4831353.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGILPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            53229..53450
                     /locus_tag="ACG804_000395"
     CDS             53229..53450
                     /locus_tag="ACG804_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831354.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            53481..53663
                     /locus_tag="ACG804_000396"
     CDS             53481..53663
                     /locus_tag="ACG804_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HFS4831355.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            53663..54076
                     /locus_tag="ACG804_000397"
     CDS             53663..54076
                     /locus_tag="ACG804_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HFS4831356.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            54199..55380
                     /locus_tag="ACG804_000398"
     CDS             54199..55380
                     /locus_tag="ACG804_000398"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4831357.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(55451..55615)
                     /locus_tag="ACG804_000399"
     CDS             complement(55451..55615)
                     /locus_tag="ACG804_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831358.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            55769..55842
                     /locus_tag="ACG804_000400"
     tRNA            55769..55842
                     /locus_tag="ACG804_000400"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:55803..55805,aa:Arg,seq:cct)
     gene            complement(55911..57050)
                     /locus_tag="ACG804_000401"
     CDS             complement(55911..57050)
                     /locus_tag="ACG804_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4831359.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(57349..57984)
                     /locus_tag="ACG804_000402"
     CDS             complement(57349..57984)
                     /locus_tag="ACG804_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831360.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINNASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(58097..58732)
                     /locus_tag="ACG804_000403"
     CDS             complement(58097..58732)
                     /locus_tag="ACG804_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HFS4831361.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(58766..59227)
                     /locus_tag="ACG804_000404"
     CDS             complement(58766..59227)
                     /locus_tag="ACG804_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4429 domain-containing protein"
                     /protein_id="HFS4831362.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
BASE COUNT        19440 a        10014 c        12551 g        17291 t
ORIGIN      
        1 gaaagaagtt gaaaacgata cctgattaca aaaaaataac ttttataagt tctataacgt
       61 tgattatatt tttaattctt attcttctcg tcgtcttggt tccccgaatt tttggtttga
      121 ctccttatat tattgaggac aaagaaatga gtccatatta tgcacaagga aatctgatat
      181 atgtacgacc gaaaaataca aatgagattt tagtcggaga tattattaca tattatgaaa
      241 attcaggaaa aaaaatctcg acgcgtcgcg taatagccgt tgaaaacaac cacgaagatt
      301 tttatacaaa agctgataca aagacttata ttgagcctgg agtagtaaaa aagagaaata
      361 ttatcggtag tcccatcttt cagattccat atattggact agtcctttca aaaacggcat
      421 ttgcatggat tcaggggtta ttctttacga ttgctttttg cctaacagga atcacagcat
      481 ggaatacctt tgtagagttg aaaaagaagc ggagacgaac acagaaattt ttgtaagaat
      541 gttaaaaaca taaatgtatt ccagagatcc aacgactctt ctgaacatga aacacgagaa
      601 aacactcatg cagcttgtag atttagtcag ttgttcgtat aatgtgtgaa gaggaggagt
      661 agtatgcgca atgaaatgat gcatcgtcct gtagtcaaag aagaactatt ggattttatg
      721 cgtacccagc aaaaaaaatt accgggtgag ctaggcaaac tggaagaaga agctcatgta
      781 gcagaagtac cagttattcc ccatgaaaca gttgtatttt tgaaattttt acttggacag
      841 cttcagcctg aacgaatctt ggagatcgga gcagctatcg gtttttcatc aagtgtcatg
      901 gccacgacaa tcggagaaaa cgctcatgtt acgacaattg atcgtttcga tgtcatgatc
      961 gagaaagcta aaaaaaacta tgaacgtcta ggactgacag ataaagtgac tttgcttgaa
     1021 ggtcaagcag cagatatctt gccggagttg tctggtccgt atgactttat ttttatggat
     1081 agtgcaaaat caaaatatat tgaattttta cctgaatgct tacgtttgtt aagaaaaggt
     1141 ggcgttttga tggtagatga catcttccaa ggaggaacga tcttgctccc agatgaagag
     1201 attccccgtg gcaaacgagc tatccatcgt aaattaaatg aatttcttcg tgttgtgatg
     1261 gatcatcccg atttgacatc gacaatcttg ccattaggtg atggtgtgat cttaatgaca
     1321 aaggaatcag aaacaatcga gttgtgatac atgattatgg cagcctgtag ataatcgatt
     1381 gaatcgaggg ctcaattcga acttgatgta aaagtttcta tatttgtaag tcaattaaag
     1441 gatacaggaa atctaaataa acaggagtag catgaagtca atgtagctcc tgttttcaat
     1501 tgataacctt agaacagctg aaggagaatg tctcgtttta aaagattgat ttagtagttg
     1561 ggccaaaata attcattatt tgctaattaa ataactattt cgtattgaca gaagcaattt
     1621 aattatctat aattattgat gttccgctga ttcttgtcat agtagctcag ctggatagag
     1681 catccgcctt ctaagcggac ggtcgggggt tcgaatccct cctgtgacgc taaaaaaccg
     1741 ttagaaactg aggtttctaa cggtttttct ttgttttttg tgccaatatt gtttgttttc
     1801 aaaggcaaat aaaataaaaa aacatcctta tcgagtacaa ttataaggag caaaaaaata
     1861 aaactcatca gaaaagagga agaagatatg acgatactat ctagaatttt agtgactcta
     1921 gttgcaattg aattttttta tatcatgtat atcgaaacgg tgagaactga ttctgacacg
     1981 acaagtaggg tttttaaaat gagtaaagaa gagttaagca gaaaatctgt tcaaacattg
     2041 tttaagaacc aaggagtgta caatggacta ttaggagtgg gactacttta tggagcttat
     2101 ctttcttccg catctaaaga aatcacaagt atgctattaa tatctatttt ttttgttgca
     2161 ttatatggca gtttgactag cgatcgttgg attttactca aacaaggtgg gctagctctg
     2221 ttggcattgc tttctatttt cttataaata tagaaaaaat aagaatttat ctaacaggaa
     2281 actttgtgaa aaatattact ttatctcatg aaatatgata ttctaatgaa tggtatttta
     2341 gaaaatttca tgaaaaagga gttagatagg tgttcaaaaa ttatgtttcc tcactaaaaa
     2401 aagaattttc aggttatgat ctttcaagat ttcagaaaga tcttttggct gggatcacag
     2461 tagctgctgt agcattgcct ttagccttgg cttttggggt atcaagcgga gctgatgcgg
     2521 ccgcaggttt gattacggct atcattgccg gtatcgttat tggcggttta tcaggcggtt
     2581 tttatcaaat atcaggtccg acaggtgcga tggcagctat cttgatgtct attgcggcaa
     2641 caaagggaat gcaaggtgta ttgcttgcta cttttttagc gggtctattt ttacttgcag
     2701 caggactttt ccgattagga acactgactt cttttatccc agcacccgta attacggggt
     2761 ttacttcagg tattgctatc attattgcat taggtcagat cgataattta tttggtgttc
     2821 actcggaagg tacaaacgtt attgaaaaac taagtagtta tcaaacgata ggatttccga
     2881 taaacacagc ctctttgatc atgggagggc tagtcatttt agggatgttt atctatccaa
     2941 aaaaatgggc gaaacgaatg cctagttcgc tgctggctat cattttggca acagcagtta
     3001 tgctattgtt ccatttacca gtagcaactg tgggtaagat tccacaaaca ttgatcagta
     3061 gtaatcgttt gaatatggga gattttagct tttctgcctt gcaacaagtg gcagttccag
     3121 ctattagcat tgctttatta ggaatgattg aaagcttgct atgtggtgct tcggctggcc
     3181 gaatggcaaa taagccctta gatagcaatc aagaattaat ggcgcaagga attggaaatc
     3241 tgttgcttcc tttctttggc gggattcctg ctactgcggc catcgcccgt acaagcgtgg
     3301 ccatcaaatc tggtgcacaa actagattag ctggtatgat acatgcagtt gtcttactgc
     3361 tctccatgct tgtttttgcg ccagtgatgt cacagattcc aatgccagca cttgcaggtg
     3421 ttttgattgt gacggcttgg cgtatgaatg aatgggaaac gatcaaggag ctatttacta
     3481 ataaatattg gtcagcagtt ctattgttta tccttacgat gatttgtaca gttatctttg
     3541 atttaagtat tgctatcgtg atcggggtga tcggcggctg tgtatttttt gttgtcaaaa
     3601 gcgctgctat cacgatttca ttagaaacga tcgattggca aagaatgggg ctgccagaaa
     3661 cggaaaagct gaataactgg acagtagtgt atattagtgg tccactgttt tttatgtctt
     3721 cagaaaaact caaaaataaa ttggaagaac taaatcatca cgatggtgtc attttctcca
     3781 tgcgaggcgt accaagtatt gatttgacgg cacgtgcagt ttttgatgaa tttcaagaaa
     3841 aagcagagca aagaggacaa acgattatct atacttcctt gcagccagaa gtagaaaaac
     3901 aactttctca cttgtgggaa catacattca cgcatcaaca tcaaacagtt gctcatgcgt
     3961 tgacagcttt acatgcgaaa tatactgcaa ttagccatta aaacaatgaa aaagaacaga
     4021 caagactgta aactgaagat tttatggtct tgtctgttct ttttaatatt gctgtaaaag
     4081 tgaagctagt acttgccagt cttgatggat aacaggtaca agggagcgat tgtagaaaat
     4141 agctgctgga tgaaaaagtg gaagaattcg atagtttttt tctgaccatt cgtaggcatc
     4201 cttttgttct gttaattgta agacaggccc tgtatagagt tgaccatgat ttttggtaac
     4261 cgtatattct ttgccaagta aacgttgaag accaatgttt ccaagtgtcg caattaattt
     4321 tggctggacc ttcatcagtt cgtaatccaa tattggtgca tgcgcaaata cttcggaacg
     4381 agtaggtgtc cgatttggat aaacagtttc tgactgttgt gtccgtttat tgatccgatg
     4441 agtcacgcga tacgggcggc tccttacagc actggtgata tacacctctt ctcgtgttaa
     4501 gccagttgaa gaaagtgcct gcatcaattc ttttccagct tgaccgctaa aaggaacatg
     4561 cgtatcaatc tctgttttcc ctggggcttc tcccacgagc atcagtttag gatgaagagg
     4621 tccttgccca gcgataaatc cttctacagg acggccgttc attcttaaag aagcttcttg
     4681 tatcagttct tttgggtatt ccatttatgc tcctcctttt tcttttatta taagaataaa
     4741 agaaacacaa tgcgactatt ttatttggta gaactgtgag gatagaaaag cagaagtatt
     4801 gcttgaattt ttgttttact ttttgatttt aaatttagtt gactaacggt tgctgttctg
     4861 gtaagctagt actgttgtaa ttgtggactc cacagctaca accgctcaga acaagtaata
     4921 agcacagcat atgctgtcac ttcggatggc gagtctaagt atatcagaag gaggtgcttt
     4981 atagcatgta cgcaattatt aaaactggtg gtaaacaagt aaaagttgaa gtgggacaag
     5041 caatctatgt tgaaaaactt gacgttgaag caggagaaaa agttgttttt gacgaagtta
     5101 tcttagtagg cggagaatct acaaaagtag gcgctccaac tgttgcaggt gcaactgttg
     5161 aaggtactgt tgaaaaacac ggcaaacaaa agaaagtcgt tactttcaaa tacaaaccta
     5221 aaaaacattc acaccgtaaa caaggtcatc gtcaaccata tacaaaagtg gttatcgacg
     5281 cgatcaacgc ttaatagcgt ttgagaaaga aggcctatat atgatcaaag gaacatttaa
     5341 gcgaaatgac gcaggtcaga tcgtttcatt cactttgacc gggcatgctg atgctggtcc
     5401 ttatggaagt gatatcgttt gtgcgggtgt ttctgcgtta gcgatcagca ctgtcaacgg
     5461 gattgcctca ttagccggtt ttgagccgat tgttgaaatg aatgaagaag aaggcggtta
     5521 tctttatacc gaagtcactt caggaatgac acaagaacaa aacaatattg ctgagattct
     5581 attagaaaat cttttattag gattacaatc gatagaagct gaaaactcag aatatatcca
     5641 aattaaaaca attaatgata aataggaggt gcagaccatg ttgttatcta tgaatctaca
     5701 attatttgcc cacaaaaaag gtggcggttc tacatctaac ggccgtgact cagaatcaaa
     5761 acgtctaggt gctaaacgtg ctgatggaca aacagttaca ggtggatcaa ttctttaccg
     5821 tcaacgcggt acaaaaatct atccaggtgt aaacgtgggt atcggtggag acgacacttt
     5881 atttgcaaaa gttgatggcg tagtacgttt cgaacgtaaa ggccgtaaca aaaaacaagt
     5941 gtctgtttat ccagtagctc aagaagctta attgaatctt atgattaaag aggttgtgac
     6001 aagacttttg tcacagcctt ttttgtttat aaaaataaaa gttgtagtgg aggctacgaa
     6061 gtttactttg tctttttaca cttaatattt ttttgccaat ttggaatcag gatgttttga
     6121 taactatcgt tttcaattga tggaagctat attgtttgct atcagtgaaa taattatatg
     6181 gtaaacagtg ttctttttct tgtttccatt ataaaaatcg tatcgggatt tttcgttctt
     6241 ttaaattgaa catttctatc tatccgcgtg ttatcaacaa aacaaaatca ggtaaatagt
     6301 tgacgaaaca gaaataaata catagtatta tgttttgaag cctaagtaca atagtctata
     6361 gaaaaggagc gataccattg gcaaaacgca ttgaccgaat ttatatgtat gtcaaagaaa
     6421 aaaccgctca tttaacaaag gcagaatatg atcaaggagt aacaacacag gaaattgctg
     6481 aagtgttagg gattcagcga acaaatagca gtaaagatct gaatcagcta gtgcgcgaag
     6541 gaaaactgat aaagacagac ggacgaccag tacgttacat atatcaaaca ctcgttacgc
     6601 acgtaaagcc agttacaaaa catgtagtca gttacaaaga aacgccggtc tctgaagaaa
     6661 aaaatacact ccaaatagat actaaggata tctttgcaaa aatcattgga gctaacggca
     6721 gcatgaaaaa ttcagtggaa caggcaaaag ctgcgatttt gtatccgcca agaggattaa
     6781 attgtttgat tacaggacct accggatcag gaaagactta ttttgcacac gcgatgtatc
     6841 attttgcaaa agcgcatcat gtaatagatg aggaaacgga actgattgtt ttcaattgtg
     6901 ctgattatgc caataaccct gagcttttga tgagtcattt atttgggtac gcaaaaggtg
     6961 cttttacagg cgcagatgaa gaaaaaatgg ggattatcga tcaagcggat ggcggtatgc
     7021 tgtttttgga tgagattcac cggttgccgc ctgaaggtca agaaatgatc ttttacttta
     7081 tggatcatgg aacttacagt cgtcttgggg aaacaacgaa atcccatgaa gcaaatgtac
     7141 ggatcgtagg tgcgaccaca gaagacccag gttcttctct attagaaact tttgttcggc
     7201 gtatcccaat caatatcaaa cttccggctt ttgaaaaacg tcctgcaaat gagaaagtcg
     7261 atttagtaaa aatcatgatt gcccacgaag caaaccgcac gcagcgaaag atttctttga
     7321 cagaagatgt agcaaaagca ttgatcggca gtgtgaccta tggaaatata ggacaattga
     7381 agtcaaatat ccagttagta tgtgcacgag gatttctaaa tcatatgcaa tcacccgaaa
     7441 tctcgatcac aatcgatgat ttgacagaag ggattcgtag cggattgatt caattagcaa
     7501 gcaaccgcag tgcaatggca gagctttcta aaatattgga gccaaagata actgtagcac
     7561 caaatgatac gatcatgaaa atccaatcgg actcctatga gttaccttat aatctatatg
     7621 atatcatcgg agataaagca gctttactga agtcggatgg tttggatcaa gaagcaatca
     7681 atcatttcat ttctacagat atcaacatcc atctgaagtc tttctataaa gaccatggtt
     7741 tttcttttaa tgcagacagc aaattagcag aatttgtaga tccgaaaatc atagaagtga
     7801 ccaatcagat ttatgtaatg gtcaaaagat ctttaccata tgagtttcag caaaacttta
     7861 tttatgctat gagcttgcat atcagttctt ttttgaaaaa aatcaactta ggagaagaac
     7921 ggcatacgaa tgataacatc cgtgagatgg cttttgattt tccagatgaa tatgctgttg
     7981 cgaaagaagt gcgtagttat atcgaaacgt attttcaagt ggagattcca gaaagtgaag
     8041 actattactt gaccgttcta ctcgtctcgt tacgggcaaa tcaagcaagc ggcagaatcg
     8101 gtgtagtcgt tgcagctcac ggaaacagca cagcaagcag tatggtccaa gttgtccaac
     8161 agttgttaga tgcagagaac gtacgagcag tagacatgcc tttggatatg gatccgaaaa
     8221 cagcattgga ccgaattgaa cgcaatgtac aagaagtaga tgaaggaagc ggggtcatac
     8281 tcttagtaga tatggggtcc cttgcgtcgt ttaattcgca aattcaaaga gacactggaa
     8341 ttccagtacg tactgttgat atggtaacaa cttctctagt tttggaaact gtacgaaagg
     8401 tctcagtatt agggacagat ctagatatgt tgcatgaatc attgaaaaat tttcgaggtt
     8461 acgcagaaat atcttctgta gaatctgttc aggaagcaaa acctattcat aagaaaaaag
     8521 ctgttttggc tatctgcgca tctggcgaag gtacagcaca aagaatcaaa gaattgatcg
     8581 aacgagcggt aaacaagcgt caagaaacag aattagaagt tctagctttg tcgattgtgg
     8641 aagtgaaaga agaactgcca gttatccaaa aagaatatca gatcatagct actactggga
     8701 ttactgattt gaatatccaa gccccattta ttcctttaga acgttttatt gatcaaaata
     8761 tcgaagtcat tttggatcag ttgctgatgg aatcagaatt ggaggaaact gaattcatct
     8821 ccctagatga agagtcagct aaaaatacgt gtgttgagtt tatctctgat aacttcatct
     8881 ttattaatgg tagtaagtta atcgatccaa tgtggcaatt ttctacacaa atctctcaga
     8941 cgacgggaat cggcgatgaa gaatatggat tcaaaatcaa cctagtgatg cacacagcag
     9001 gaatgatcga acgtattatt cggaatgaac cattgactgt ggaagaaaac gaattgacaa
     9061 atacaacgaa tgatcctctt tatagccaat tggcagcctc agttgttctg ttggaagatc
     9121 agataaaagt aaaagtgccg atagaagaaa tgtattatct gctacgtcta gtccataatc
     9181 agttagataa aaaagaatac actgtgccat gaatacacaa aaacgataca cttttatagt
     9241 gtatcgtttt tgtgtattgg ttaagaatcc tttaaattca attagtgtat cgtaaaaaag
     9301 ttggcacgct ttttgcttat agtagtgtgt gctaggaggt ggttgttcac acagaaatga
     9361 taggggtttc tgtgaagtag tgaggaagaa ggagttttgc agatggatat tcgattggca
     9421 cgtatagatg atcgtttaat ccacgggcaa gtcgcaacag tttggtcgaa gcaaacaggt
     9481 gttgaacgta tcattgtgat cagcgatgta gtcgctcaag ataaattgag aaagtttcta
     9541 ctaaaagaag ctgcaccgcc ggggatcaca gcaaatgtaa taaccgtgca gaaaatgatt
     9601 caaatctatc atagtggatt attatcacga gcaaaagtga tgcttttatt caccaatccc
     9661 caagatgttg aagcggttgt ccgctgcggt gtacagttga agtcgttgaa tatcggcggt
     9721 atgagtttta ctgaaggcaa atcaatgatt accaattttg tttcagtaaa tcaacaagat
     9781 attgattcct ttcgttactt gaacagtcaa gaagtggagt tagagattcg aaaagtacct
     9841 gctgacagga aaatcctttt gatggaacta ctagcgaaaa tcaaaaaggt gtagcaagaa
     9901 tggttgttgg aaaaggtcaa ataattctgt tgtaatggtt agcaattatt aatatttttg
     9961 aatttgttac aacaaaagta aataggaggt ataaatatgg tagggattat cctagcaagt
    10021 catggacaat ttgctgaagg aatcttacaa tccggttcaa tgatctttgg cgaacaagaa
    10081 aacgtcaaag ccgtgatttt gaaaccaagt gaaggtccag atgacttgag agccaaattg
    10141 gaagaagcgg ttgcttcttt tgataatcaa gacgaagtgt tattcttagt tgatttatgg
    10201 ggcggaacac cgttcaatca atcaaacaca ttattcgaag agcacaaaga taaatgggca
    10261 atcgtcagcg gtttgaattt accaatgttg attgaagcct acgcatcacg cttttcaatg
    10321 gaatctgctc atgaaattgc agcacacatc attgaaacag caaaagacgg tgtaaaagta
    10381 aaaccggaag aattagaacc ggcagaagca ccgaaagcag cagttgaaga cgcacaacct
    10441 aaaggagcac ttccagaagg aactgtggtc ggagacggaa aaatcaaata tgtattagca
    10501 cgtgttgact cacgtctgtt acatggacaa gttgcgacag cttggacaaa agcagtgcaa
    10561 ccaaaccgta ttatcgttgt ttcagatgca gtatcaaagg atgatctgcg taagagacta
    10621 atcgaacaag ctgctcctcc aggtgtaaaa gcaaatgtta ttcctattag caaaatgatc
    10681 gaagtagcaa aagaccctcg ttttggaaat accaaagcat tgcttttatt tgaaaatcct
    10741 gaagacgtat tgacagctgt tgaaggtggc gtagacatca aagaattaaa tgttgggtca
    10801 atggcgcatt cggtcggtaa agtcgttgta agtaaagtat tgtctatggg acaagaagac
    10861 gttgaagcgt ttgagaagct tgaacaaaaa ggtgtgaaat tcgatgtacg taaagtacct
    10921 aatgattcac gcgataacat ggatgatatt ttgaaaaaag caaaagctga attagcaaaa
    10981 gcgtaataaa taatattaaa atttatagga ggcttatcat gtctattatt tcaataattt
    11041 tagtcgtatt agttgccttt ctagctggta tggaaggtat tcttgatgaa tttcaatttc
    11101 atcaaccact agtggcatgt acattgatcg gtttagttac cggtaacctc gaagctggta
    11161 tcgtacttgg cggtacgctt cagatgatcg ctttaggttg ggcaaatatc ggtgccgctg
    11221 tagcaccaga tgctgcatta gcatcagtag catcagcaat tattttagtt ttaggtggac
    11281 aaggtgttaa aggtgttcct tctgcgatcg cgattgccgt tcctttggct gttgcagggt
    11341 tgttcttaac aatgatcgta cgtacaatcg ctgttccaat cgttcatttg atggatgcgg
    11401 ctgctgaaga aggaaacatc cgtaaggttg aaatgtggca catcattgct gtatgtttac
    11461 aaggggttcg tatcgcggtc ccagcagcag cgttgctatt tatcccagca caaactgtgc
    11521 aatcattcct tgaatcaatg ccagcatggt taacagatgg tatggctatc ggtgggggaa
    11581 tggtcgtagc tgtaggttac gctttggtaa tcaacatgat ggctacaaaa gaagtatggc
    11641 cattcttcgt tattggtttc gttgtagctg caatttctca attaacattg attgctctag
    11701 gtgctttagg tgttgcatta gctcttattt acttgaacct ttctaaaatg ggtggttcat
    11761 caaataatgg aggcggaagc aattctggtg accctttagg cgacattttg aatgactatt
    11821 aatcttgaag gaggaaaata aaatggcaga agaaaaaatc aaattatcaa aaaaagatcg
    11881 tttagctgtt gcgtggcgct ctaccttcat tcaaggttca tggaactacg aacgtatgca
    11941 aaacggtggc tgggcatttt ctatgattcc agcaatcaaa aaattataca aaacaaaaga
    12001 agaacgttct gcagcattaa aacgtcactt ggaattcttt aatacacacc catacattgc
    12061 ttctccaatt ttaggggtta cattggctct ggaagaagaa cgtgcgaatg gcgcgcctgt
    12121 tgatgatgta gcgattcaag gggttaaagt aggtatgatg ggtcctttag ctggtgttgg
    12181 tgacccagtg ttctggttta cagtacgtcc aatgctaggt gcactaggtg cttcattagc
    12241 tatgggagga aatatccttg gaccaatcat cttcttctta ggttggaaca ttattcgttg
    12301 ggcattcatg tggtatacac aagaatttgg ctacaaagct ggttctaaaa ttactgatga
    12361 cctttctggc ggattgttac aagacgtaac aaaaggtgct tcaattttag ggatgttcgt
    12421 attagctgcc cttgtacaaa gatgggtatc aatcaaattc ttaccagttg tatcaactgt
    12481 aaaattagat aaaggtgctt acatcgaatg ggataaattg ccttcaggtg gtgaaggaat
    12541 caagagtgca tttgaacaag ttaataatgg cttagccctt tctcctgaaa aggtaacaac
    12601 attacaagac aacttagacc aattgattcc tggtttagct gcattaggat taacattgtt
    12661 atgtatgtgg ttgcttaaga aaaaggtttc tccaatcgtt atcatccttg gtttattcgt
    12721 agtcggtgtt gttggacacg tcatcggact tttataatcc ataaaaatat agctcgggcg
    12781 ttgtcccgag ctttttttat atagtatact gttcataaac aaatatctgg agggagaaaa
    12841 tggttcaatc aatcaataca aaagtagact tggtaattga tgctacttcg tttacgggtc
    12901 tgacagatta cgggcaaatc atgataggta ataatggttt tgagttttac catgcgcgag
    12961 atagacgcaa atatatccaa attccatggg aagaagtgga ttatgtacta gcatcagtca
    13021 tgctaaaggg aaaatggatt cctcgatatg ccattcaaac gaaaaaaaat ggtacataca
    13081 cattttcttc caaagaacct aaaaaagtgc ttcgtgcgat cagagaatat gtagatgaag
    13141 atagaatggt acaatcattg agtttctttg atgtagtgaa acgtggtatt cgtagtatgt
    13201 ttaaacgcaa gtaaaaaata aagaaaactt ctaagaggag gttttcttta tttttttact
    13261 ttgcagaaga aaatatgaaa tagcaaaacc aattatttgt cccctttaaa tcccatatgc
    13321 taaaattgat tagcaaagaa ggaggttata ttatgagttg gttatggaca ttgattgttg
    13381 gagccgtgat cggagcaatt gcaggtgcga tcaccagtaa aggaaattcg atgggctgtg
    13441 taacgaatat cattgctgga ctagtcggtt caagtattgg acaagcgatt ttcggcgaat
    13501 ggggaccaaa agctgcaggt atggcactta ttccatctat tttaggcgca gtgattttgg
    13561 tagcagttgt ctcatttttc tttggaaaac gatcataagt ttttacaaaa tagtaaacta
    13621 aaaggagttg cagcgagact gtgactcctt tttggcttta tttatttaaa ataaaaagaa
    13681 gttttccgga aatttttatt taactgtcgt gtacgaagaa aagtttgcta taatggaaaa
    13741 aagcgtgcaa agaaagaggg agtttcatta tgatgctacg tgtagaaaaa ttgcgcaaaa
    13801 aaatgcaaga agaaaatttg gattcatttt tggttaccag tccgtacaat cttcgttact
    13861 taacgaactt tacaggtacg acaggattag ctgttattac tttggaaaaa gcatttttta
    13921 ttactgattt tcgttatacc gagcaggcgg cagcgcaggc tcaagggttt gaaattatta
    13981 aaaatgtcgg acctattttt gatgaggtag caaacttagt acgcaaagaa gaactgcact
    14041 cattagcttt tgaggaaaca acagtctcat ttttagaata ttcggtttta gaagaaatca
    14101 tcgatgcgga attagtacct gtttcacaga tgatcgaaga actcagagaa gtgaaagatg
    14161 aagaagaaat cgctattatc gaaaaagcat gtcatattgc ggatatggca tatgatcaca
    14221 tcctgaaaat gatccaaccg ggcatgactg agattgaagt cgcaaatcaa ctagactttt
    14281 atatgcgttc tcttggcgct tcaggtgttt cttttgatac gatcgttgct agcggattgc
    14341 gttcggctat gccgcatggt gtagcaagca aaaaaatcat cgaacaaggt gacttgatca
    14401 cattggactt tggttgctat tacgaagggt acgtttccga tatgacacgt acattcgcta
    14461 ttggtgatcc tggggaaaaa ttaaaagaaa tttatcaaat agtcttagat gctcaattag
    14521 cagttattga tgctgcaaaa ccaggaatga ctggtgtcca attagatgca gttgctagag
    14581 attatatttc aaaacatggt tacggggaag catttggaca ttctacagga catgggatcg
    14641 gtttagagat ccacgaagga ccaaacgttt cttctcgtgc agaaaagcaa tttgtaccag
    14701 gaaatgtgat cactgatgaa ccagggatct acttaccagg aatcggtgga gtacgtattg
    14761 aggatgactt gttgatcaca gaagatggaa atcgtgtgtt gactcgttca ccaaaagaat
    14821 tgatcatctt atagtttcat caatagaaga agtaagcgta aaaatcagtg ttcacagact
    14881 ttgttataga aaatcactcg atttaatgat acactataga agaactttta agctgtaaga
    14941 gataataaag ttgggtgttt tctccaattc atagcagttt gcagctgatc ggcggcagtt
    15001 ttcttaccac gtgatcacta tgccgcatca tagagaattc ggatgtatct cgtgcttagg
    15061 caaagggagg aataaataaa tggcagatga aaaaaatttg attttaaacg caaaccaaga
    15121 tttaggagag atcgtgatcg ctcctgaagt catcgaagta attatcggga ttgcagcttc
    15181 taaagtagaa ggcgtatacg gaatgcgcgg aacttttgcc agcaatgtca ctgaattatt
    15241 aggacgtgca gctcacggaa aaggtgttta cttagcaaac gaggaagatg gcttgaaagt
    15301 agatctttac tgttatctag aatatggtgt ttcagttcct aaagtagcaa tggaaatgca
    15361 ggaacgggtc agccagcaag tccttttcat gacggatatc gatttatctg aagtcaatat
    15421 ccatgtagta gctgttgttc ctgaaaaatt agaacaacca acaatcgaag aactttttga
    15481 agacgaagag gaagagaatg aataaagaat tatcaagaca cgagattcgg gaaatggcat
    15541 tgcaggcttt atttccatta gacttcaatg cagacctaac aaaagaagat gcgattttca
    15601 acgcaatcga attagaccac cgcgacatga tcaacgaaga tgaatcagag tttgttcctg
    15661 tttatcttga tacgctagtt ggcggtgtct gtgcaaaaaa agatgaattg gataaagtga
    15721 ttgaaaaaca tttaaaaaac aattggcaca tcaatcggat ctcaaaaatg gatttggtga
    15781 tcttgcgtat cgcgattttt gaaatgactt atgtgacaga tgtaccagcg gctgttgctt
    15841 taaatgaagc aatcgagttg gcaaaaacat ttagtgatga ccgttcacgt aaattcgtca
    15901 acggtgtttt atccaatgta ttgaaagaat tagaagctgg ggcgtaagtc ctagcttttt
    15961 tctatgaatc atcataaacc tgttataaat cgggaaaatt ctatggtaga atgaaaacac
    16021 aaaaaatatc tgggagtggt tagatggcag aattgattaa cggaaaagaa ttagctgaaa
    16081 aaatgcaggc agagattgct gaaaaaatcc aaaaattgaa agataatggt atccatcccg
    16141 gattagtcgt tttattggta ggggaaaatc cagccagcca aatctatgta agaaataaag
    16201 aacgtgtagc aaaagaaatc ggaatccatt cattggtaga gcgttatcct gagacgattt
    16261 ctgaagacga actacttgca gaaattgaaa aatacaatca agatcctagt tttcatggta
    16321 tattggtcca attaccattg ccaaagcata tagatgaaga aaagatcctg ttagctatcc
    16381 gccctgaaaa agacgtagac ggttttcatc cgatgaattt aggcagactc cttgcgggta
    16441 aaccggacaa gattccttgt actccatacg gcatcatgaa aatgtttgaa gcttattcta
    16501 tcgatccggc gggtaaacga gcagtagtta tcggacgaag caatatcgtc ggtaaaccga
    16561 tggctcagct actcttgatg gcagatgcaa ctgttactgt tgctcattct aaaaccgaaa
    16621 atctggctga actggcacaa gaagcagata ttttagtcgt agcaatagga cgtggacatt
    16681 ttgtcacaaa agaattcgta aaaccaggtg ctgtagtgat agatgtaggg atgaatcgtg
    16741 atgctaacgg taagctgatc ggtgatgtga aatttgatga agtggagcct attgcaggct
    16801 ggatcactcc tgtgccaaag ggtgtagggc caatgactat cacgatgctg atgtatcaaa
    16861 ccgtaaaatc tgccgaagct tttggagcag gtgaatagat ggcacaagaa tatttaactg
    16921 tcactacatt aacgaagtat ttgaaaagaa aatttgatgc cgatccttat ttagaacgcg
    16981 tatatttaac aggcgaaata tcgaatttcc gtttacgtgc caatgcccat caatatttca
    17041 gcttaaaaga tgaccatgca aaaatatctg ctattatgtt caaaggagca ttccaaaaat
    17101 tacgattcca gccaaaagaa ggaatgaaag tccttgtcgt tgggcgtatt tcattatatg
    17161 aagcgggagg ttcttatcaa atctatgtag agcacatgga gcctgatgga ataggtgctt
    17221 tatatcaaga attggaagaa cgaaaagaaa agctgatgaa ggaaggcctt tttcaagggc
    17281 ctaaaaaaat gctgccacgt ttcccaaagc gaatcgcggt ccttaccagt ccaagcggag
    17341 cggttatccg cgatatcatc acgacggtga aaagaagata tccaattgtc caattggttt
    17401 tgttcccaac agttgtacaa ggaaaccaag cagcggacaa tgttgtcagg aatatccaga
    17461 gagtagaaga gatgggcaat ttcgatacaa tgatcatcgg tcgtgggggt ggttcgattg
    17521 aggatttatg gccgtttaat gaagagcggg ttgctcgggc gatttatcaa gctaatacgc
    17581 cggtgatttc atctgtagga catgaaacag ataccacgat cgctgattta gtagcagatg
    17641 ttcgggctgc cactccaaca gcagctgcag aattagctgt tcctgttttg tcagaagagt
    17701 tgatgcgcat tcaagaacgg caagctagat tgcagcaggc gtttgtacgc cagatccagc
    17761 gcaaacaaga acggttcgag cgtgctcgac gttcctatgt atttcggcag cctgaaagat
    17821 tgtatgaagg tcagaccatc aaattagacc agttgaaaca gcgattatat caagctacac
    17881 agcaaattta tcatgcgaaa gaaaaacaaa cgatcgcatt aagccaccaa ttggaacaag
    17941 tggctccgct ttatcgagtt aaagcagctc gccaagaaac tgcttatcta gaaaaacgct
    18001 tagaagagaa aatccaacaa tatatgaaac aacagcagca gcgttttgct caagctgttc
    18061 aatctcttga tttgttgagt ccattgaaaa tcatgggaag aggctacagc tatacgacgt
    18121 taaatgatca agtagtaaaa agtgtcaccg agattcatca aggggatttg ctgacgatcc
    18181 attatcaaga tggaatcgtt aaaggacaag tacaagagat agacaaagga gaataaaaat
    18241 atggaaaatc caacttttga agagtcactg caagaattag aaaaaattgt catgcagtta
    18301 gaacaaggag acgttccatt agaatcagct ctagattcgt ttaaacgagg aatggaatta
    18361 agcaaacatt gccaagatac attagctaaa gcagaagaga ccttgacgaa aatgatgaca
    18421 gaatcaaatg aagaagttga ttttgacgga aacgaggaaa gctgagatga gattaactga
    18481 cttttcagct attcatctac ctgctgtaga aaaagaaatc ttgtcttttt tagatgagca
    18541 tacaacggat agaggactct atgatgcgat gagttattca gtgaaagcag gcgggaaaag
    18601 aatacgtccc ttattacttt taacggccgt tgcttccttt gatgagccta ttgatgttcc
    18661 cgtctatcaa gtagcagctg ctttagaaat ggtgcatacg tattccttga tccacgatga
    18721 tttgcctgcg atggacaatg atgatcttcg tagaggaaaa cctaccaatc ataaagtatt
    18781 cggcgaagca ttagctatat tggccggaga tggtttgctt acaggagcat tccagctaat
    18841 cagtatggca cacttaggta attctcctaa gcttctgctg cttcagcaat tagctgtttg
    18901 tgcgggatca caaggtatgg ttgctgggca agctgcagat atcgagggcg aatcgaaaaa
    18961 gctttcttta gaagaattag catttattca tgaaagaaag acagggcatt tgattcgtta
    19021 tgccttgctg gctggtggca tattagcgaa gcaacctgaa gaaatcttat tgctacttca
    19081 acgattagcc gaacatttag gtttagcttt tcagataaga gatgatctac tcgatgtgat
    19141 tggtacaacg aaaacattag ggaaaacagc tggtaaagat gaacgtatgg aaaaaaatac
    19201 ttacccgcgt ttattaggcc tagaaaagac acgtgaggcg ttggagattg agctgttatc
    19261 cgccaacaag atcatagaca aattagaaga ggacgttttt tcttttgatg gcgggctgat
    19321 gcgccagatg atcaagcaat ttgatgtgga gaaatgaggg aaagaatgga aaaagaacgc
    19381 gtagatgtat tagcggtcaa acaaggatta tttgaaacaa gagaacaagc caaacgttca
    19441 gtgatggctg gtttgattta caacgaaaaa aacgagcggt ttgataaacc gggagaaaaa
    19501 attccagtga gtagtgaatt aagagtcaaa ggtaaaaaac ttccttatgt ttctcgaggg
    19561 ggattaaaat tagaaaaagc actcaaagca tttgatctat ctgttgaagg aaaaacattg
    19621 ttagatattg gtgcatccac tggcggattt actgatgcag ctttgcaaaa tggcgcaaaa
    19681 atgagttatg ctttagacgt tggctacaat cagctagctt ggaaaataag acaagatcct
    19741 agagtcgtcg taatggaaag agtgaatttt cgttatgcaa aacccgaaga ctttacctta
    19801 ggaattccag aagttgctgt tatcgatgtt tcttttattt cactaaaact gatgctgcct
    19861 ccattacatg ctattttaaa agaagaggga gaagtgattg ctttaatcaa accccaattc
    19921 gaagcaggca gagaagctgt agggaaaaac ggaattgttc gtgaccctca gacccatcaa
    19981 aaagttttag aagacatttt gtcatttgcg gcacaaggtg gatatgatgt gctggaatta
    20041 agttattctc cgatcacggg gggagaagga aatatcgagt tcttggctca cttgaggaaa
    20101 gtacccgaaa gcggaacaat caattcagct attaatatgg cagaagtggt ttcaaatgca
    20161 cacgaacagt ttgaccataa ataaattgta actgtgaaaa tcaagtgaga agtatgcgga
    20221 ttcttcttta ttataccaag gaaataagct atcattgatt aagaagaata tgctaaggag
    20281 cgaagacgta atgagaaaaa aagatcggca tcgtttgatt actcgattgt tgagtgagca
    20341 agatatccga aagcaggaag aatttgttga aatcctgaaa agcaaaggaa tatctgttac
    20401 tcaagctacg atttccagag atataaagga actgaaactg atcaaggtac cggcttcaga
    20461 tggcggctac cgttatagca taccagctga aacaaacgaa gatgtaaata ctaaattgga
    20521 aaaactatta aaagacgctt tcgtggcagt tgaccaaatg gaaaaatttg ttattttgaa
    20581 aacattgccg ggaaatgctt cggcagcagc aaatttgatt gataaacgtt acaagaaaga
    20641 attattttcg attatcaatg atgacgataa tgttttgatg attacacgaa ctgaagacca
    20701 ggcagtttta ttgaagaaag acttcctgca ttacctttaa gttgaggagc gaatgtgatg
    20761 ctacaagaaa tcagtattac taactttgcg attattccgg aattgcggct ttcttttcac
    20821 gaaggaatga ccgcgctgac cggagagact ggtgcgggta aatccattat tatcgatgct
    20881 ttaggtctgt tagcaggagg aagaggttca agcgattata tacgtcaagg agcagaaaaa
    20941 tgtgtgcttg aagggttgtt tgaactacca aaacaagaag gattctctga actgatggtt
    21001 gaattaggga tcgaaacaga tgaggacaat ctgattgttc gacgggatat gtccttaact
    21061 ggaaaaaatg tttgtcgagt gaatggtcat attatcacat tagctaatct gagaagaatc
    21121 ggcagttatt tagtagatat ccaaggacaa aacgaacatc aggaactgct ccagcctgaa
    21181 tcacatcttg ctttattgga tcgttttgga gatgtagctt tccaacagaa gaaaaagagt
    21241 tatcagcaag aatatatctc ttatcgtgag ctggaaaaaa gggtacgaaa agtgcagcaa
    21301 aatgaaaaat cctatgttca gagaatagat atgctccatt tccagcaaga agaaatagct
    21361 gctgctgatt tgcaagtcgg agaagaagag aaattaaaag aagaaagaga aaaacttagc
    21421 aattatcaaa aaattgctga tggattagct gcaggttacg gagcactgac gaataatgaa
    21481 caaaacagtg tagatggtgt tggcttggcc gtttcagaac tgcaagggat cgcccatcta
    21541 gatgtggagt atgaagcaat ttatgaaaat atccaaagtg cttactattt gctgcaagat
    21601 gcaatcggcg atatgagtcg tcagattgat ttattggagt tagatgagag tcgtttagaa
    21661 gaagttacgc aacgtttaga attaatccga cagttgaaac gtaaatacgg cgaatccatt
    21721 gagtcaatat tggcttacta tgacgaaatc accgaagagc tagcttcttc tgatttttca
    21781 gaaggtcaat tggacaaaat gaaagaggaa ctagagcaaa aagagcttct acttcagcaa
    21841 caagccgcag atcttcatga agcgcgtaaa aaaatcgcaa aagaattgga aaaatccatt
    21901 ctgcatgaat tgaaaagtct gtatatggaa aacactgagt ttgaggtacg tttcttaaaa
    21961 gaagaaaata gacaattgaa tcatgatgga tttgaccaaa tcgaatttta cattacgacc
    22021 aatccaggag agccactgaa gcctttggtg aaagtcgctt ctggtggcga actgtctcgg
    22081 atgttgcttg ctttgaaaac tattttttct tctgagcaag gtgtgacaag tattattttt
    22141 gatgaagtgg atacaggtgt gagcggaaga gttgcacagg ccatcgcaga taaaatttct
    22201 caaatatcga aatactctca agttttgtgc atcactcatc tgcctcaagt tgctgcagtc
    22261 gccgactatc aatattatat tgtgaaagca gtgattgatg gacgtacgca aacttctgtt
    22321 tcagagttga aaacaaaaga aagagaagaa gaaattgcac gtatgctggc tggaagtgag
    22381 attacaaaac tcacactcga acatgcaaaa gaactattga aactcgcaaa aaggacctga
    22441 gccacctcgc agtggttcag gtccttttca gcagctgata gctatatttt atttttacat
    22501 gacactcatt acagcagtca atacaacaga tccaatcgtt aaaatcagca ttgtccaaat
    22561 gacaaatttt gttactttag caaaagtact tgtttgtttt ttttcacgca ttgttttcaa
    22621 cctcgtcatt aattagttga ttcaagtgta caatcttttt tccatttcca caagagggct
    22681 tttttataaa aacttccctt tttttaaata ataggtagtt acgatacaaa taaataatgt
    22741 taatagaact agccatataa aggcatcatc cctttcagca ataggtaact taatgttcat
    22801 tccatagata ctgccgacga ttgtcggtat agttaaaata atcgttaaag aagttaaaat
    22861 tttcataata ttattcagat tattcgatac gattgctgaa aaagtctgat tcatttgttc
    22921 tactagtttt aattgaatgc gagaagtagt cattgcctgc tctgtttcca ccaatacatc
    22981 acgtaaatga tttttcaaag catgattttc ttggaaaagt ttattttgcg ctagttcttt
    23041 caatgcatct aaattagcag aagtcgcttc tctgaaataa acgaggcttt tttggatatc
    23101 catgatttga taaagttgtt tgttttcagt ggatacttga agtttggctt ccaaagtatc
    23161 gcattgagat tgaagcgtag ctaaataact gttgtaagag agtgtgacct gccaaatgaa
    23221 ttgaaagaag atattgagat taggcgaaat atcacttttt ggaaaggtct ggctaaagac
    23281 tttctttaaa aacagtggtt catgattcgt aattgtgata agcttctttt tgggcgtcaa
    23341 aataatagag agcgggtatg tatccacttg aaaataaccg ctaggacttg ttttagcaaa
    23401 aggatattgt aacaataata acgctggctt tgtcaacttt gattgattga attcttctgt
    23461 acgggaattt tctgcatcgt ccaatatgga agtgatgtaa tctgacggaa tttcaaattg
    23521 atgtgtcagc tgatgaatct cttcttgatt aggacgttct acacaatacc agatcgtttg
    23581 gtcagtttcc tttccggtat tacgcagttt ctcattatct aatgtaaaat atttgatcat
    23641 gattttcctc ctgttgcctg tttcttttat tataacggat agggaattgg aatacatgga
    23701 atgtgtttgt aagatataga atataactgc ataaatttaa ataaaatgaa acagttgtgt
    23761 aaagtatata cagtatactt gaagcaacga taaaaaagga gtttacgttc atgggcacat
    23821 tcacaccact tatcttgttt tggtatattt acccggtaat cgttttgttt ggttgccaat
    23881 ttcttgtaaa attattttcg ttaaatcgtc gttttaaaat aaaagcccct gatttggcga
    23941 ttcctttttt gtggggcggt atgcatgcat gcattgtcta gaaatacagg gacaatttct
    24001 atcttaccgt ttttctttat ttctgttttg ctaatgggaa tttgtattgc tgttttccaa
    24061 gcatattatt atgaagaaat tatttatccg cgttatttca agatgacttg gcgtttggtt
    24121 tttctgttga caatcgtctt gtacgctgtc ttgatcattg tgaacatact ttcttaccta
    24181 tgaaaaaaat agaaaagctg taaaaagtct tttaaaaggc tttttgcagc ttgattttta
    24241 aaaaaatgtt tatgaataaa aaaagttgtt cccggatttc ccagaaaagg tggtagaaag
    24301 tgggggattg tggtagacta attttagtta gtggaggaat ggggggcttt caatgttgat
    24361 gggtgaattc caacataata ttgatgcaaa aggacgttta atcgtgccct caaaacttcg
    24421 tgaagaactt ggcgaaaagt ttgttctgac acgcggattg gatggctgtc ttttcggcta
    24481 tccgatgagc gaatgggaaa atctggaagc taaactgaac gaaatgccgt tggctaaaaa
    24541 agacgcacgt acttttgtgc gattcttcta ttcggctgcc actgaatgcg aacttgataa
    24601 acaaggacga atcaatatac ccagcacgtt aagaaattat gcagctttga caaaaggttg
    24661 cgtagtcatc ggtgtatcta accgaattga aatttgggat gagacacgat ggcaagattt
    24721 ttctgcagca gcagaagaga actttgacga aattgctgaa agtatgattg atttcggact
    24781 ataagaatag gaagaggctg actaatgact gaaacatttc aacactatac agtcatgttg
    24841 aaagaaacgg tagatggatt gaacatcaaa ccggatggcg tttatgtaga ctgtacactc
    24901 ggcggtgccg gacatagtga atatttatta agccaactaa gttctaaagg gcatctgtat
    24961 gcgtttgacc aagatcaaaa agcaatcgat cacgccaagc tgcgtttagc ttcttatgtc
    25021 gaacaaggta tggtcacatt tatcaaagcg aacttcagag aattagaaga acgcttgagt
    25081 gagcatgtag ataaggtaga cggcattttg tatgatctag gggtttcctc tcctcagcta
    25141 gatgaagcag aacgtggatt tagttatcat caagatgcac cgttggatat gcgcatggat
    25201 cagtcagctc ctttatccgc ttatcacgta attaatgaat attcctacca tgaattagta
    25261 aagattttct tccgctatgg cgaggagaaa ttttccaaac aaattgctcg tgaaatcgaa
    25321 cgagtacgaa aaacaaaacc aatccaaaca actggtgagc ttgtcgaaat cattaaacaa
    25381 gtcatcccag ctcccgcaag aagaaaaggc gggcatcctg caaaaagaat ttttcaagct
    25441 gtgcggattg cagtaaatga cgaactcggt gccgaagagg cctctttaga acaggcaatc
    25501 cggttattga aagtcaatgg aagaatcagc gtaatcacat tccattcatt ggaagacaga
    25561 attgtcaaaa gtatgtttaa agaatatagt acggtacaag atctaccacc gggacttcct
    25621 gtcatacctg acgaattcca accagaactg aaagtcatta ctcgtaaacc aatccttcct
    25681 tcagaggaag agctaacaga aaacaatcga tcacgcagtg caaagttacg tattgcagaa
    25741 aaaataagaa tgaaagagga gtagaatgat ggcagaatta aagaaaatgc aagattacga
    25801 atatgattta cctgaattgg tggatcagcc ggaacaacaa atgcctgatt cttcttcgaa
    25861 tcaagaaatc attcttccac aatcaccggc aaaacgatta aagcagattt ctgctttgga
    25921 aaaaattgct gtggcaagcg tggcgattgc tattgttgct ttatgtgttt taacagttat
    25981 gctgcgcaca aatatcagcg gagctgaaaa agaaatcacg tcaatacaaa cagaaatcaa
    26041 tgataaaaag caagaaaaaa cgagtttaga acaagaaaaa aacgaacttt ctcgtactga
    26101 acggattaaa caaatcgcag aagaaaaagg attgtctatt aatgacgaca atttaaggaa
    26161 agtgaagtaa atgagtctta aaaataaaat tcggcggttt atggaaaaga aaaatctaaa
    26221 tccgatgaac aatcgcaaaa aagtaggtat cattttattt gctacgagta ttggattgtt
    26281 ctttttattt gccgtccgtt tctcgtatat cgttattgga ggtcatgttg ctggtacctc
    26341 attagctgaa aaaacaaaac agttgtacca aggaagtgaa gtagtaaaag caaaaagagg
    26401 aacgatttat gatcgtaacg gtgtggcgct cgcagaagat gcctcctctt attcaattaa
    26461 agcgatactc tcaaaaacat atacctctgg ggataaaaaa ctgtatgttg aagaaaagaa
    26521 ttttgataaa atagcagaaa tcctgcataa gaatctttct atagacaaaa aagatgcact
    26581 gaatatttta gaggacggcg caaaaaaaga gctgtatcaa gttgaatttg gtagctatgg
    26641 gaaaaatatc tcccaagaaa ccaagcaaaa catcgaagcg gacatgaaaa aagaaggtgt
    26701 cgctggtctt tattttgtcg accatcaggc tcggatgtat ccaaatggcg tcttttcttc
    26761 tcattttatt ggatacgcag ttccagacaa agatgagaat ggcttagttg gtaaactagg
    26821 tttggagtct gcttacaatg atatcttgag cggtaaagat ggtaagatta tttatcaaaa
    26881 agataatttt caaaatcctc tgccaggtac agtggcagaa gaagaaaaag ctgtcgacgg
    26941 acaagatatc tacacgactt tagacagcag actacaaagt tatttagaaa cactgatgga
    27001 tcaagtaaat gaagaatatc agccagaaga attgacagca gtcctgatga aagcaaaaac
    27061 cggagaaatc ttggcaatgg gacaacgacc tactttcaat cctgaaacaa tggaaggatt
    27121 gactggaaaa gatgctatct ggcgtaattt cttggtacaa gatagttatg aaccaggatc
    27181 aaccatgaaa gttttcacta ctgcagctgc tatcgaagaa ggagaattca acgagaatga
    27241 aaccttccaa tctggaaaaa tccaagtaga agatgctacg atcaatgacc atgactttgg
    27301 tgaaaaaggt gtgctgacca tgcgtcaagc tctttcatgg tcaagtaacg tcgggatggt
    27361 catactggaa cagcgattag gcggacgatg gtataactat ttacaaaaac tgggatttgg
    27421 acaaagtact cattctggat tagatgatga agtaaacggt gctttaccta cattaaatat
    27481 tgtcgaccga gcaatgagtg cttatggaca agcggtaggt gtgacgaatt tccaaatgat
    27541 gaaagctttc acttctattg cgaataacgg tacaatgatt caacctcgat atatcagcaa
    27601 agtggtggat ccccaaactg gagaagagcg aacaactcaa acagaagttc tagggcaacc
    27661 tttttcaaaa gaaacaacag aaaaagtccg tgaatatatg agagatgttg tcgaaagcga
    27721 aaactacggt agtgcttatg gtgtatatag tgtacctgga tacaatgtat cggcaaaaaa
    27781 cggaacagcc caaatcgctt ctgatacagg gggatatcaa acaggagata cagcctacct
    27841 gtattcgatt gtggagatgg ttccttctga agatccagac tatgtcttgt atctaacaat
    27901 gaaacaccct aagacatatg atcgaatggc attggctaaa atcgcaaatc cattgatgaa
    27961 acgggcaatg gattttaaag aaactgaaga agattcagat acagaaacaa aaacagaaaa
    28021 agtatccgta gccgattatc gtaatcttga agcggacgtt gcagcagctg atgctcaaaa
    28081 aagtggactg caacctgtag tgatcggtaa tggtaaaaaa gtacaaaaac aatctactgc
    28141 caacggtgat cagttgatct ctggagaaaa actgatccta tatactggtg gtgataagct
    28201 gatgcctgac gtaacaggat ggtcaaaagc agatatcatg aagctgggga aaatcctcgg
    28261 tattgaagtt agttttgatg gagatggtta ttgtgtcaaa caagaacttg ctccatatga
    28321 aaaaatcact gaagacaaac ttagttttac tttagaagaa taagaagaga aataggagag
    28381 aaaagagcat ggaatggaca caagcattga ttcccattgt cagcagttgt gcaatgacaa
    28441 ttgccgcaat gccgctattt attggttatt ttcaaatgaa aaagcaaggt caggcgattc
    28501 gtgaggaggg accaaagtgg cacaatagca aagccggaac tcctacaatg ggcggcttag
    28561 tgtttctgat cggctctatt ttgacaggaa tttgggttgg agcttggcaa aaacagctaa
    28621 ctcctactct tttcatcttg ctttttgtat tagcgttata cggagtaatc ggctttcttg
    28681 atgattttat aaaaatattc aagaaaagaa acatgggact gaactcgaag cagaaattga
    28741 ttggacagat tctaggggga atcatctttt atcttgttta ccgttctgaa ggttatccag
    28801 gtgtattgaa tttcttcgga ctagatctac ctttaggaat catttatggt attttcgctc
    28861 tcttctggct tgttggattt tcaaatgcag taaatctgac agatggcatc gatggattag
    28921 ttgctggctt aggaagtatc tcttttgcag cttacggtct aattgcttgg catcagcatc
    28981 agtatgatgt attaatcatt tgcttaagtg ttttaggagg tttactgggt ttcttcgtct
    29041 acaacagaaa acctgccaag atttttatgg gagatgtcgg ttcattagcg ttgggcggac
    29101 ttttagcggc aatttctata atgctaaacc aagaatggac attgcttttg attggtttga
    29161 tctatgttat ggaaacagca agtgtgatgc ttcaagttac ttcctttaag cttacaggaa
    29221 aacgaatttt taaaatgtct ccaattcatc atcactttga aatgtgcgga tggtcggagt
    29281 ggaagattga tacagttttt tggttgatca gcattgtgac ttcgttgatc acattatgga
    29341 tcgtttggta ggagatgacg ggaaatgaaa aaaatatcaa catatgaaaa taagaaagtg
    29401 cttgtcttag gactcgcaaa aagcggagta agtgcggcca aattattaca tgaattgggc
    29461 gcacttgtca ccgttaatga tggaaaacct tttgacgaaa atccggaagc acaagagctg
    29521 ctttctttag ggataaaagt aataacaggt agtcatccaa tcgaattgtt ggatgaagaa
    29581 ttttcattga tggtcaaaaa tccagggatt ccctacagtc atcctttagt agcaaaagcc
    29641 caagaaatgg gtattccggt aattacggaa gttgagctag cttacgaagt agcggaatgc
    29701 ccaattattg ggattacagg aacgaacgga aaaacaacga caacaacgat gacaggacta
    29761 ctactgaatg caggagcaga tcaaggaatt gcacgtttag cgggtaatat tgggtatcca
    29821 gcaagtggtg tagcgcaaga agcaaaatca gaagataaaa ttgtgatgga attgtctagc
    29881 ttccaactca tgggaatcac agatttccgc cctcatatag cggtgattac caatatctat
    29941 gaagcacata ttgattatca tggtacaaga aaagaatatg tcaaagctaa atggaacctt
    30001 caaaaaaaca tgacagaaaa agattatctg atccttaact ggaatcagtc agaactacaa
    30061 gaattagcgc aaagaacaaa agcacgcgta ctgcctttct cgacaaaaga agtgttggaa
    30121 gacggtgtgt atgctgacga ttactcaata tactataaaa aagaaaaaat aatggaaata
    30181 tctgaacttg gcgtaccagg taagcataat gtagaaaatg cactagctgc tatttctgta
    30241 gcaaaattgt atggtatatc aaatgaagct atacgagaaa cgttgcattt tttccatggc
    30301 gtaccacatc gtacgcaata tgtaggagaa atccaaggca gaaaatttta taatgattca
    30361 aaagcaacca atattttagc gactaaaatg gctctaagtg gatttgaaac gtctaaggtc
    30421 gtgttattgg ctggcggatt agacagagga aatacatttg atgaattaat tccttcatta
    30481 aaaggaatca aagcaatggt cgtatttggc caaacaaaag aaaagttgat ggatgctgga
    30541 aaaaaagcag gcatcgagac aatagtaaca gccgattctg tagaacaagc agttccttta
    30601 gcattagaaa acagtacaga tggtgatgta gttttattat caccagcgaa tgccagctgg
    30661 gatcaatacc caaattttga aactagagga aacagattca tggaagctgt gaaccgatta
    30721 aaatagaaaa agtagaagcg agcgataaaa aatgaaaatt ttggttacag gcggaggaac
    30781 agggggacat atttatccag ctcttgcctt tgtcaattat gtaaagactc aagaaccgaa
    30841 tgctgaattc atgtatgtgg gagcaaaacg aggtctagaa aacaaaatcg tccctgatac
    30901 aggaatgcct ttccatacct tggagattca aggatttaaa cgaaaaattt ccatgcataa
    30961 catcaagacg gtccgattgt ttcttaagag tatccgtcaa gcaaaaaaaa tcctcagtga
    31021 ttttcaacca gatatcgtta tcggtactgg aggatatgtt tccggagcgg tagtgtacgc
    31081 tgcagccaaa atgggtattc caacagttat ccatgaacaa aacagtgtac caggtgttac
    31141 caataaattt ttaagccgat atgtggatcg gatcgctctt tcatttaaag atgcggcttc
    31201 cttttttcct gaaaacaaag cagttcttgt aggtaatcct cgagcacaag aagtagcaga
    31261 tactaaaaaa tcagatattt tgaaaacatt tgatttggat ccagaaaaga aaacagtctt
    31321 gatttttggc ggtagtcaag gagcacttaa aatcaatcaa gcagtatcag tttttttaag
    31381 tgaatatatt ccttcttctt accaagtttt gtatgcttca ggagatagat attatgaaga
    31441 gatcctaaat aaaataaatc ctgaaataca aaatattagt gtccagcctt atatcaaaaa
    31501 tatggcagag gtcatggctt ccagtgatct gctggtgggg cgtgctggtg caacttcgat
    31561 cgcagaattc acagctctgg ggttaccggc agtgttggtt cccagcccat atgttacgaa
    31621 tgatcatcag actaaaaatg caatgagtct tgttcacgca ggagcagcaa aaatgattgc
    31681 agataatgaa ctaacaggtg aatcactaag tcagacagtc aacgaaatca tgggtgatga
    31741 agaattgcaa aagcaaatgt gccgagcttc taaagaacaa ggaatccctg atgcttcaaa
    31801 acgtctttat gacttagtaa aacaaataat caaaaaataa aggcggtggt cttagtgagt
    31861 aagaaaaaag aaccaaaaaa attgtctcat ccgtcttctg atgaaaacaa tttgactcct
    31921 tggcaaaagg ctaaccgaaa atatctggca gaacaagaga tgaaaaacca agagccaaaa
    31981 aaagaagaca taacattaga tacacccctt tcagattctg aagaagaaaa aacggttcaa
    32041 gaggaacagc aagaagaaag ccagtccgag aaaaaaatcg aattttttga agagatcaag
    32101 caaaagaaaa acggtggacc atataacggt tcttttttga accggctgcc caatttaaaa
    32161 agtcaacggc acaaagtact atttcgtcgg ttagctttga tcatcactgt attgggtata
    32221 ccgctgattt ttttgatcta ttatgtttct ccttatagca aattacaagc agttgcagta
    32281 tcaggcaata agacagtcaa cagccaagaa atcatctctg atacaaaatt gtcattagga
    32341 gaaaatgttt ggggacagta ttttcatcga tctacttata tcgatcgcct taaaaaagca
    32401 cagccaagaa tcgaaacagc aaatatacat ttcaaaggga tgaatgaatt cgatttggat
    32461 gtaacagaat ataaagagat tgctttgatc gcaaaaaaca atcaatacta cccagtgatt
    32521 gaaaatggaa cagtattaga tgaaaaagta gcaaatccta caaaaaatct ccctatcttg
    32581 gaagagttca aagactctgc aaaaatcaaa gaattaacaa agcaatacaa tcagttatca
    32641 tcagaattac aaaaagcaat ttctgaaatc aagtacacgc caagagcaag caataaaaat
    32701 ctgatccaat tgaatatgaa tgacggcaat caagttattg taaatatcaa taatcttgcg
    32761 aaccaaatga aatattattc gcaagtagcc aaagatatgg atgaaaaagg tgtgatcgac
    32821 atggaagttg gtatcttctc gcatccttac ggtagcactc aagaaacgga agaatcgggc
    32881 caatcggaag aaacaactga aagtgaagaa aatgcggatc aaacaaacga atcaagtgaa
    32941 gaggcagaaa cgcaaaaagc acaaacacct ggatcgtcta gcacaaacgg atcatctgat
    33001 tcaaatgatt caagtgaaac aagtcaaata gaagataatc caagtacaac tccgtcaagt
    33061 ttaaatgaaa attgataaaa caactttaaa aagtaagaat gtactttcta aaaaccagta
    33121 atttatggta gaattggaag cagtgaatat atctattaat aagtatattt taaaacggac
    33181 gctagttgtt cgcttgtata tggaatagta agtaggaggg aatcccattc atggcaaaaa
    33241 caggaatgta tgtaggcctt gatattggaa cgacatctgt taaagttgtc gtggctgaat
    33301 atatcgacag ccaaatgaat attattggag taggaaacgc aaaatcagaa gggattaacc
    33361 gaggcattat cgttgatatc gataaaacgg tccaagcgat acaacgagca gtacgacaag
    33421 cagaagaaaa agcaggtatc cagatcaaag gcgtaagtgt cggtttgcca gcaaacatgc
    33481 ttgaagtaga aaattgccag ggaatgattg cagttaacgg agattcaaag gaaatcaccg
    33541 atgaagatgt cagaaatgtg gcttcagctg cccttgttcg ttcaatacct cctgaacgtc
    33601 aaatcgtgtc aatattgcca caagatttta ctgtcgatgg gttcgaggga atcaaagatc
    33661 ctcgtggaat gatcggcgta agattagaaa tgtacggtct gttgtttaca ggacctaaaa
    33721 cgatcatcca taacatacgt aaatgcgtgg aaaatgccgg attaatcgtc aacgaaatgg
    33781 tgattactcc tttagcgctg actgaatcaa ttctttctga cggagaaaaa gattttggta
    33841 cgatcgtcat tgatatgggt ggcggccaaa caacaacggc tgttatgcat gataagcaat
    33901 tgaagtttac caatcttgac caagaaggtg gcgaatttgt cactaaagat atctctattg
    33961 tattaaatac gtcatttaac aatgcagaag cgttgaaaat aaactacggg gatgcatacc
    34021 cagaacggac atcaccagat gaagaatttc cagtagatgt gattggtcag tcagaaccag
    34081 tgaaagtcga tgaacgctac ttgtcagaaa ttatttcagc tcgaatggaa cagattttca
    34141 acaaagcaaa agatgcattg gaccaaatcg aagcattaga gttgccaggt ggcgtcgtat
    34201 tgacaggcgg agctgctagt cttcctggtg ttgtggactt ggcacaagaa atcttcggcg
    34261 taaatgtaaa attgtatgtt ccaaatcaca tggggctgag aaacccggta tttacaaatg
    34321 taataagtat cgtggattat tcagcaaact tgagtgaagt gtatcaattg gcaaaaattg
    34381 ctgttacggg tgaaacctca gcagctcgtc aaatggtagt tgaacaagaa acaacaaaca
    34441 catatgagag ctatgaagca cctgaagaaa caatctacga tgagccggaa ccaaaagagt
    34501 ccggagaaaa tgtaaaaaat aaaatcaagg gtttctttac aaatattttt gattaattca
    34561 tcctgggagg aataagatat ggaattctca attgataata atatcaatga cggcgcagta
    34621 atcaaagtca tcggagtcgg tggtggcggt ggaaatgctg taaaccgaat gattgaagaa
    34681 aacgttaaag gtgttgaatt cattacagcc aacacagacg tgcaagcatt aaaaaattca
    34741 aaagctgaaa cagttatcca attaggcccc aaatatactc gtggtttagg tgctggttct
    34801 cagccagaag ttggacaaaa agcggcagaa gaaagtgaac aatccttacg cgaagcttta
    34861 gacggtgcag atatgatttt catcactgca ggaatgggtg gaggaaccgg tacaggtgct
    34921 gcaccaatcg ttgcaggtat cgcgaaagaa ttgggcgcat tgactgttgg tgtcgtgaca
    34981 cgtccattca cttttgaagg accgaaacgt ggccgttttg ctgcagaagg tatcgctcgt
    35041 ttgaaagaaa atgtggatac attattaatt atctcaaata accgtttatt agaagttgta
    35101 gataaaaaga caccgatgct tgaagctttc cgtgaagcag ataatgtttt acgacaaggt
    35161 gtacaaggta tctctgattt gatcacagcg ccaggttacg ttaaccttga ctttgctgac
    35221 gtgaaaacag tgatggaaaa ccaaggtaca gcattgatgg ggatcggtgt ggctagtgga
    35281 gaagatcgcg tagtagaagc aacgaaaaaa gcaatctcct ctccattgct tgaaacatct
    35341 attgatggag ctgaacaagt acttcttaac atcacaggcg gtttggatat gacattgttc
    35401 gaagcacaag atgcttcaga tatcgtagca aatgcagcaa ctggcgatgt aaatatcatt
    35461 ctaggtacat ctatcaatga agaaatgggc gatgaaatcc gtgtgacggt catcgcaaca
    35521 ggtatcgatg aatcaaaaaa ggaacgcaag tctagccgac cagctagaca agcacaaatg
    35581 caatcacctg ctcaaaagac tgtattagat atggatcaag ctaaaccaac ttcttcagaa
    35641 gaagaaaaca gttttggcga ttgggatatc agacgtgaac aaaatgttcg tcctagagtt
    35701 gatgattcca attttgacaa tatcgaaaaa aaagaatttg atacattcaa ccgcgaagaa
    35761 acaaaatctc atggcgatga tgaattaaat acgccaccgt ttttccgtcg taaaaaataa
    35821 aggagaggaa gagcacatga ttgctgacaa cttgcagaaa atcaagcaag aaattcagga
    35881 ttcgtgtgct cttgttcatc gtgatccgaa agaagttaca ttagtagctg taacaaaatc
    35941 tgttgaatcc gctcaagctg aagaattggt tagagctggc gttatgaatt gtgcagaaaa
    36001 ccgagtagat aaattattag aaaagaaaca agatttattt gattttcctg aaataaagtg
    36061 gcatttaatt ggtaatttac agcgcagaaa ggtaaaattg attgtaaatg aaattgatta
    36121 ctttcatgcg ttggacagtt taagattagc agaagaaatc cagaagcggt tagagaaaga
    36181 attatcctgt tttattgaag taaatgtttc tggtgaggaa tcaaaacatg gaatttcacc
    36241 agatgagctt ttaccgtttg tggaatcttt agctgcctgc acaaaaatca aggttgttgg
    36301 gttgatgact atggcgccta aagaagcttc tgatgagcaa atccataaag tgtttggtac
    36361 gctgaaagaa ttgcgtgatc ttgttcaagc aaaaggttat gcccatgcac catgtagtga
    36421 attaagtatg gggatgagtc aagactttca aattgcgatt gaagaaggtg caacatttat
    36481 ccgtgtagga acagcgctat tcaaagacga ataaaggagg aacaaaaatg ccgcttttaa
    36541 acagaggagc aattgctaat tttttcggat tagctgatga ggaagagtac gaataccaag
    36601 attatcctga aacaacaaaa aaggctgtac agccaactaa aaaaaataca acacagaatc
    36661 aatcaactca ttctgtatct gctgcgaata ctcatgaaaa acaaaaaacg gcgacttcac
    36721 gtcctgtaac gcatgaaagt attcagccgg ctgaaaagaa aaaagtaatt gaactacatc
    36781 aatcacctac aaaaactgta gcgaaagaaa gaacagcttc aagaacctct acacaaccta
    36841 aagcaaatct tgctggaaaa atcactgtaa tggaaccaag agcttattct gaagctatgg
    36901 cgattgctaa acgaatcatt gctggagaag caaccttagt gaattttcat ttagtagaag
    36961 aaaaacaagc gagaagaatc gttgattttc taacaggaac agtttatgca ctagatggag
    37021 atatcaaacg tgttggagat gagatttttc tttgtacacc gactgggatg gagattgaca
    37081 gttcaaccgc tcaatctttt gcagatgcga atttgtttga tctgtaagag gaggaactac
    37141 gatttatact attgcactat tacttcattt acttcaacgg gcagcctatt tctatagcat
    37201 tatcttgatg gtatatgcat tgctctcttg gtttccaggc gggtatcaat cagggctagg
    37261 acgattatta gctaagatct gcgaaccgta tatcagtttg ttcgatcgtc tgcctttgag
    37321 gattggaccc ttggatttca caattttagg ggcaatcctg atcttgaact tagccgtaca
    37381 aggtttagca cagatcgtta tatggataac tgtccattta gtttattgat tgaagcaaca
    37441 aaatctttat tctcagaata gataggaggg gaaaattttg gatgcaaatg tataccagca
    37501 ctttcgggca gatgaacgta catttatcga ttcggtaggc gattggattg aacaggttca
    37561 aggacaatat gcaccctatc tgaccgaatt tcttgaccca agacaatcct atattttaga
    37621 aacactgatt cgacaaagca gtgatttgcg tttcatgttt tatggcggat atgaacaggc
    37681 agaaagaaaa agatgtttga ttttccccga ttattacgaa cctgtagagg aagattttga
    37741 aacagcattg tatgaaatcc attatcctag caaatttgcc agcctaagtc atgggaaaat
    37801 ccttggaact ttagtgggaa cggggatcaa acgctcttac tttggcgata tcatctcgga
    37861 cggtgatcgc tggcaagtat ttattgcaaa tgaggtggat cattttgttg ctgcacaagt
    37921 aacaaagatt ggaaaggttg ctgtacgctt ggaaccaatc aaatacacag aaatgattat
    37981 gccgaaagat agctggacac aagaaagagg aacagttagt tccatgcgac tagacagtgt
    38041 gatctctgag atttataata tttccagaca gcggtccaag cagctgatcg aagctggtaa
    38101 agtaaaagtg aactggacag aaaatacaag acctgatttt gtacttgaac tattagatat
    38161 tatttcagtc agaggttatg gcagagtcca gatccaagaa cttgagggga agacgaaaaa
    38221 agaaaagtac agggtactgt tcggtgtatt acgtaaataa aataaaaagg tggtttactc
    38281 atggctttaa ctccattaga tatccaaaat aagacattcc cgacaaaaat gcggggatat
    38341 aatcaagacg aagtagatga tttcttagat ttagttgttc gtgactatga ggaattgact
    38401 caaagaaatc gagaattaga aaaagcagtc aaacattctg aagaaaaact tgagtacttc
    38461 aatgaattaa aagatgcttt gaaccaatca atcatcgtag ctcaagatac ggctgataaa
    38521 gtaaaaacaa gtgcaagcaa ggaatccgaa gtgatcgtta cttctgcaca aaacaaagca
    38581 gatgagttag ttgcgaacgc tgaaaaacgt gcacatcaat taacaactga tgcagaagaa
    38641 aaagcaagaa aaatcttgac agatgcaaca gaaaaagcaa gacagcttgc gacagaaact
    38701 gaagatctta agaaaaaaac acgagtattc catcaacgta tcagcttgat gcttgagtct
    38761 caattagaac aagtgaaaag tccggaatgg gatgaaattt tacaaccatt ctccagctac
    38821 gtgactgaca gccatgaagt gatcaaagaa gttttagcaa aacagcttga caatgaaaat
    38881 gatactgatg taaactcaga cacaggagtc atagaagcac ctatgacggc atttgataca
    38941 caggctattg atatctcgat cgtgcctggt gaaaatgaaa acgagtagaa cagaaaagca
    39001 ctttgttatt cttaaagcga gccgatgaga gtggaagttc ggtaagacac tgcatggtga
    39061 aagatcctct acttgagacc tgcttttccg aaattagagt aagaagcagc ggctgacctc
    39121 gttattggtc acagagagtt tgcactagat agatgcaact aaatttgggt ggtaccacgg
    39181 catgttcgtc ccttgcggct gaacatgctt ttttgtgtcc ggaaaacaaa taaaggagtg
    39241 tatggttgaa tgaaaatgaa agaaaccttg caattaggaa aaacaaaatt ccctatgcgt
    39301 ggtaatttgc caaaccgaga aggcgagtgg caaaaagaat gggaagaaaa tcgaatctac
    39361 caaaaaagac aagagttgaa cgaaggaaaa cctagctttg ttcttcatga tggacctcca
    39421 tatgccaatg gtaatatcca tttaggacat tcattgaata aaatcagtaa agacattatc
    39481 attcgttcaa aatcaatgtc tggctatcgt gcaccatatg ttccaggatg ggatacacat
    39541 ggattgccga ttgaacaagt attggctaat aaaggcgtga aacgtaaaga aatgtccatg
    39601 gcagaatact tggaaaaatg tcgtgaatat gcactttccc aagtagataa gcaacgagca
    39661 gatttcaaac gcctaggagt tgcaggagat tgggaacatc cttatgttac attagatcct
    39721 tcttatgaag ctgcacaagt acgcgtattt ggtaaaatgg ctgaaaaagg ctatatttac
    39781 aaaggattga aaccaattta ctggtctccg tcaagtgagt cttctttagc ggaagctgaa
    39841 attgaatata aagatgtaaa atctccatct atttttgtag ctttcaatgt caaagacggc
    39901 aaagatattc ttgatgaaga tacagctttt gtcatttgga cgacaacacc atggacattg
    39961 ccagcaaacc aaggtattgc tgtaaatcca aaatttacgt atgtattggt ggaagccgat
    40021 ggccgtaagt ttgtcgtagc gaaagatttg ctagaaacag tccaatcaga aatcggttgg
    40081 gaaaatgtaa cagttctaaa agaatttgct ggacaagaaa tggaatatat gactgcaagt
    40141 catccattct atgaacgtga atcacttgtg attttaggcg atcatgttac tttagacgct
    40201 ggtactggat tagtccatac tgctccagga catggggaag atgactatat cgctggtagc
    40261 aaatataaac tatctgtagt gtcacctgta gactcaaaag gattgtttac agaagaagca
    40321 cctggatttg aaggtatctt ttatgacaaa gcaaatccta tgatcactga tctattaaaa
    40381 gaaaaaggag ctttgctgaa gctagatttc tttactcata gttatcctca cgattggcgg
    40441 acgaaaaagc ctgtgatcta tcgggcaact ccacaatggt ttgcatctat cgataaattc
    40501 cgtcagaata ttttggatga agtagaaaaa gtagagtggg ttatcccatg gggtaaaaca
    40561 cgtttgtata atatgatccg tgaccgcggc gattgggtaa tttcccgtca gcgtgcatgg
    40621 ggagtaccac ttccgatttt ctatgctgaa aatggagaag caatcatcac accagaaaca
    40681 atcgaacatg tggcaaaatt atttgctgaa catggatcaa ttatctggtt tgaaaaagaa
    40741 gcgaaagaac ttcttcctga aggatttacc cacccaggtt ctcctaatgg cgaatttaca
    40801 aaagaaaaag atatcatgga tgtctggttt gattctggtt cttctcatga agctgtttta
    40861 cgtcagcgac cagaattatc attcccagca gatatgtatt tagaaggatc agaccaatat
    40921 cgtggctggt tcaactcaag tatcacgact agtgtggcta tcaatggtgt agcaccatac
    40981 aaatcagtta tttctcaagg atttgcttta gatggtgaag gccgtaagat gagtaaatct
    41041 ttaggaaaca tcattgcacc agaaaaagtg atcaaacaat ttggtgcaga tatccttcgc
    41101 ttatgggtat ctagtgtaga ttatgaagca gatgttcgtg tttctatgga tatcttaagt
    41161 caagtggcag aagtatatcg taaaatcaga aatacgatgc gtttcttatt agcgaataca
    41221 gaagatttcg atcctaaaaa agatactgtt tcgtacaatg atttacgttc tgtagacaaa
    41281 tatatgaccg ttcgattgaa ccaagtaatc aaagaaatcc gagaagaagg gtacgacaaa
    41341 tataacttca tgcatattta ccgtacagtt atgaacttct tgacggttga tctatcgtca
    41401 ttctacctgg attttgctaa agatgtagtt tatattgaag cagaagatga ttatcaacgt
    41461 cgttgcatgc aaactgtttt ctatcaaaca gctgtagctt tgacaaaatt attgactcct
    41521 atcattccgc atacagcaga agaaatctgg tcattcctga aagaagaaga ggagtacgtt
    41581 cagttaagcg agtttcctgg ttatgaagag tttgcaaacc aagaagaatt gatggatacc
    41641 tggactgctt tcatggactt ccgtgataat gtcttaaaag cattggaaga agcaagaaac
    41701 agcaaattga ttggtaaatc tttggaagca aaactaactg tttatccaaa acaacaagtt
    41761 cgtgaaatgt taaaagcttt ggatgcagat attgcacaat tattgatcgt ttcaccagac
    41821 tactttgaag ttatggcagc agatgaacaa gtgccagata acgctatggt atttgatgat
    41881 gttgctatta cagtggaaaa agcagacggg gaaacttgcg atcgctgtcg ccaagttcgt
    41941 aaagatgtag gagtagatga aaaacttcct catctatgcg gtcgttgtgc aaaaatcgtt
    42001 gaagacttct atcctgaagc tgtagctgaa ggattcgaag aaaagtaaaa gggaaaaggg
    42061 ggtgtgacat gttctttgtc acaccccctt ttgttatcaa tcgtttaatt ttccacgttc
    42121 acgataccag ttatctggtt gccagatcca ttcgaatccg tctttttcaa gtagttcgaa
    42181 agctgcttta ggtcccattg atccagcttt gtagttggga aaatccggtt gtgtttggtc
    42241 ccaagctttt cgaatgacat ccacgatatg ccaagattga gcgacttctt cccaatgaga
    42301 gaagttcgtt ccatcaccat tcaacgcatc taatagtaat ttttcgtaag cttctgggct
    42361 attttcaacc atttctgcac tatttctaaa ttccaatttg attggttccg tttcaaatcc
    42421 ttgccctact tctttcccat tcaaggataa agaaaatcct tcagttggct gaatatagat
    42481 cgttagaaca ttaggtggaa gtgtcgtatc gtcacatggt tcatcgacag atgttttgaa
    42541 tacattaaca ggaacttgtt tgaatacgat gttgatccga gtcccttttt cagtcaaacg
    42601 tttgcctgta cgtacataga aaggaacacc tgaccaacgg aagttatcga tagtgaattt
    42661 gcctgcgacg aatgtttcag tctctgattg agcatccact ttgtcttctt cgcgatagcc
    42721 cttgaattgt acaccatcca attcaccttg agcatattgc ccgcgaacga agttttctaa
    42781 cacttcttct tcgttataaa tgcggatagc tttcaatgct ttgatctttt ctgtacggat
    42841 ttctttttcg gaaaatgcta ctggcggttc cattgcaagt aatgctacaa cctgtaaaat
    42901 atgattttgc accatgtctt taagtgcgcc actatgatcg tagtagcccc cgcgatcttc
    42961 tacaccgagg ttttcgccaa aagtaatttg gatattgtcg atatagcgat tgttccattg
    43021 agcctcaaaa atattattgg caaaacggat agctgagatg ttttggatca tttcttttcc
    43081 taaataatga tcaatcctga aaatatcttg ttctgggaat acttctctga tttgctggtt
    43141 caattcaaaa gcagactggt aatcagaacc gaacggtttt tctatgatca aacgattgaa
    43201 gccatttttt gtcataatat tttgtgattt caaatgagaa acgatcgttc caaaaaattg
    43261 aggtgccata gccaaataat agacacggtt accgtttaat tgatagtgtc catctaatcg
    43321 gtcagacaat tcttttaatg tctgataatg cgttgaatca tttacatcat gggattgata
    43381 gtaaaaatgg cttgcaaagg tagttgcttc ttcatctgaa ggattcaatg cacggattgt
    43441 ttctttgaca acttcacggt agtgctcatc gctccaggga cggcgagcgg ttccgattac
    43501 agcaaaatgc tcgcctaaat ttccttttct gtaaaggcgg aacaaagacg ggtacaattt
    43561 acgctgggct aggtcacctg taccgccgaa tatcgtaaac aatacatttt tttcattaga
    43621 catgtggata cactccttta tattttatcg acaaaaatcg tgctggccgc cttaaagctg
    43681 acggggattt tctttctatc attttggata gtgatcggtc cttcataagc tgcgatgtca
    43741 acgatctcat attcttcgtt gatattcagg tcaatagtga ctaagtaatc caacaattct
    43801 ttttcatcaa gcactcgtgc gatacgcact tttgtaccga caggatagga ctccaatgtt
    43861 tgtcggcgtt cttcatggac aacttcctct tttttaggaa tcgatcctcc atgaggacaa
    43921 tgttcaggat gattcaaata gttttctaaa tgatctgcaa gatgttccga agtcacatgt
    43981 tccaatactt cagcatcatc atggacttca ttccagctat agtctaaatg ttcaactaaa
    44041 aaaacttccc ataagcgatg tttgcgaatc agactgctag ctttttgcag tccgcttgca
    44101 gtcaattgta caccttgata aggggaatgt tctacaagct cttctttcac aagtttagaa
    44161 atcatttcac tgacagatgc agctgagaca tctagactag atacgatttg tttattgttg
    44221 actttcgttg tatctccacc tagttctaaa atgattttca aataatcttc tcgatttggt
    44281 gtcatattcg atcatccttt catggtaaaa aaccatcatt agtaagtgta acaaaaaaaa
    44341 cgttaattga ctatttttct aaataaaaaa caaaggattt ttagacgttt ttacaacaaa
    44401 aaacgaaaga tgatagagaa gactcattct ttcgtttata aaggatatat atatacattg
    44461 ggagggatct atttttcaga taacaactta tatgaagtgt ctgcagattc gtcataaaga
    44521 gtttgttcgg gataagaaaa gataagataa aaaccatact gatcacgtac gactaaacga
    44581 tattcatcta tttctaccac agatgtgcca agagactgac cgttgatcaa aaacgtgtaa
    44641 tcagatgtaa tctgtaattg ttgtttttgc tggctatcac taaagaacca tgtaccttga
    44701 tactttgaga gtccttctga cttttccgct tgttttttct ttttcaagta aataaaactt
    44761 gagagaacgg taatgagtga accaagaaaa tagatcattt tttttatcac caaatcactc
    44821 ctttatgaga aaataatcgc atagacatat tctttcttct ttatttcatt gtaccgaata
    44881 aaagctaaaa tttctctaag actttcgact ggttttttta ctgtttttct acaaattatg
    44941 ataggataca tagtaggaag aaaggtgaca taatttgaag tatcagcaag tggaaatagc
    45001 tttttttatt gaccgcccga atcggtttat agcacattgt atgaaaaaag acggagaaat
    45061 aattattgcg catgtcaaaa atacaggtag aggaaaagag gtcctgatac caggcgctga
    45121 agtggctatt gtatttgctc ctggacctaa acggaaaacc gcctatgatc tgattgctgt
    45181 aaaaaagaag ggtgactggt ttaatatcga tagtcaattg cctaatcggc tggcaattga
    45241 tggtatttta gacggcacga tccttttacc aggattaact ggtccattta cggtatacaa
    45301 gcgtgaagta acttatcttc actccaaatt tgatatttat ttagagacgg tggtcggaca
    45361 aaaagcattt gttgaagtca aaggtatgac acttgaaaat aaagcgattg gtgcttttcc
    45421 tgatgcgccc acactcagag gattgaaaca tataggagaa ttaacgtatg ccgcacaaga
    45481 tggttatgcc gcttatgtct tgtttattgc tcagttcgaa catcttcatc tggcaacgat
    45541 ccatgaagaa atgcaaccag cactagctga tatggttcga catgcgcagc aaagcggagt
    45601 tcaaatcctc gcctataatt gtcaagtatc ggcagatgag gtaactgtca agcaggccat
    45661 tccatttgat gtagatatcc cttttgaaga tcctatacaa tagaaagaag gtaaaataat
    45721 gatcaactta ggtattatcg gaacaaattg gattactcat caatttgtcc aagcagcttt
    45781 aagcacaaaa aaatatgaat tgacagcggt atattctaga catttggaaa aagcacagga
    45841 atttggttct cattatgaag gggatatcga attcgcaaca gatttgaaga cttttttcaa
    45901 tattactcat atggacacca tttatattgc ttctccgaat agtcttcact ttagtcaagc
    45961 taagcaagca attttggcag gaaaaaatgt gatagttgaa aagccagctt tttcgacgcc
    46021 aaaagaaatg gatgaaatca tccatttggc aaatgaacac aatgtgtatt tttttgaagc
    46081 agcaagaaat atccatgaat caggttttaa aaagattgcc gattacttac cattaaaaga
    46141 cgagataatc ggtgcaaatt tcagctatat gaaatattct tcgcgctatg accaagtatt
    46201 agatggagaa gaaccgaata tcttctcgac tcatttctca ggtggtgcat tgatggattt
    46261 aggtgtttac cttgtatatg cagctgttgc ttggtttgga atgccaaaag aagtccatta
    46321 tttcccaaga aagatttcta ctggtgtaga tggtcttgga tgggggatct tacgttatga
    46381 gaattttgat gtatcgatcc agccaggtaa aatcggtgat tcttatttac cgtcagagat
    46441 ttattttgac tcaggaacgc tagtgatgaa tggagtcaat gcaattgaac aagcacaatt
    46501 tcatgatcgc gcgcataaag aaatcattga tttggcggta acagctgcag aaaatccaat
    46561 ggcagatgaa gcagaggatt ttgccaatgt catggctcat ccgaaagatc cagcttgggg
    46621 attgttgtat gaagagtgga tcgagctagc tagaaatgtg aaccaagtga tttatgattt
    46681 aagaaaaaat ggcggcatca aattcgatgc agataatgag gaagattttt aatgaacgaa
    46741 tttgtacaag tatttcccga aaattggcag aaaaaatatg aggataaagg gtttatctca
    46801 ccttctctta ttcaacgagc agtttttcag ccactaagta ataaacaaag tatagtagcg
    46861 gtttctccta caggttcagg taaaacactg gcttatcttt ggcctctact actaaacgtg
    46921 gaaccaggtg aagcaagtgc gttggtcatt tttgcttctt ctcaagaact agctattcaa
    46981 gtagcagatg ttgcacgtga atggggaaaa gacaaagagt tgaaagtcca atctttggtg
    47041 ggcggagcca acgtcaaacg tcagattgag ggtttgaagg aaaaaccaga aatcttgatt
    47101 ggtacaccag gaagaatatt ggaattgatg aaagcaaaaa aaataaaagc acatcaagtg
    47161 aaaacaatgg tatttgatga agcagaccag ctatttgacg ctgggaacag ccaaatcatt
    47221 gatcaaattc ttcatcaagc tccaacagag tatcagctag cttttttttc agcgacagca
    47281 gatcgttccc ttgaaagcat tgaaaaaatc actgggaaaa cgtttgagac aattgacgtg
    47341 acagcagagg acgattctcg aaaaggactg agacattact ttttacgtgt accgatacga
    47401 aagaaagatg actacttgag acgtctcacg catatagaag attttcatgg tctgattttc
    47461 tttaatcaac tgactgaatt aggcgtaatg gaagaaaaat tgctgtatag aggtgtaccg
    47521 gtaggaagtc tggcctctga tcagaacaag ctactccgaa aagcagcgct agaacaattc
    47581 aaaaagaaaa tggtcagagc acttttgacc acagatgtgg cggctagagg tttagatatt
    47641 acaggtcttc cttatgtagt gaatgcagaa gttccgttaa gtgaagaagc ttatttgcat
    47701 cgttcgggaa gaactggtcg aatgggtaat gaaggaatag taattacact cgtacaagat
    47761 aataatctaa gagatttaaa acggctttta cgtccatcaa atataacact tgaagagatt
    47821 tttttatacg gaggtaagct gcaaactgag cagccaacca aagaagatgc agctcctgca
    47881 gtaaataaaa agtatgcgaa aactttttct ggaaaggagc agaacccaga atataacaaa
    47941 gaaaaaataa gaaaaaaagt taaaaataaa tcaaaaaaag agagaaataa aggagcaagg
    48001 cgcaaataag cgccttttta tgctatgatt atgaaaacgg gaacaaaatt ggttgccaga
    48061 ggaggggtta tgtgaaagaa cgtcaagaag agatcttgca gctattgaca gaaaaccaac
    48121 aaggattgac agcaagtgat gtagctgagc gcttaactat cgatcgaagc aatgcaagcc
    48181 gatatttaag tgaactatac aaggcccatc atattgtaaa aaccgctggc cgaccagtcg
    48241 tttactcttt gccaacggaa aagtcaaaat ctgatgaagt gcatgtcgac tcttctacgc
    48301 aagtgacttt tgaaacactc gttggagaaa atgattcttt aaaagtcagc atacagcagg
    48361 caaaagctgc gattctttat ccaccgcggg ggttgcatac gattattttt ggagaaactg
    48421 gtacagggaa gtcgatgttt gctgaatgta tgtatcattt tgcaatcgat tcagagatgc
    48481 tttctgcaga tgcgccattt gtttctttca attgtgcgga ttatgctcaa aatccgcaac
    48541 tgctctttgg acacatcttt gggatcaaaa aaggggctta cacaggagca gctcaagata
    48601 gtcccggtct aatagccaaa gcagacggcg gtatattgtt tttagatgag atccaccgtt
    48661 taccgccgga agggcaggaa atgctgttta ctttcattga taaaggtatt taccgtccgc
    48721 ttggagaaag tgcacaagta catgaagcat ctgttcagat cattggggcg acgactgaat
    48781 cttcagaaag tttcttatct acgttcaatc gacggattcc tatggcaatc accttgccga
    48841 atcttgcttc acgttcactg gatgagcgtt atgaaatcat ctctcttttt atcaaacaag
    48901 aagcgaatcg tttgaatcaa cgtatcgata tcgaaaaaga agcgattctt gccttcatgc
    48961 tttatgatgc ggaaggaaat atcggtcaag tgaaacgaga cttgaaacta gtctgtgcaa
    49021 aatctttttt acattaccgt actcatcatg agaaaaagct aatcattcga aaagaagaac
    49081 tttcccttca agtacaaaaa ggattactga aaatcaagga aataccggaa cgtctcgacc
    49141 gattcatgga cagcaaaagt cagtatttga catttgaacc aggatttgct gatgttgtct
    49201 ggtcacaaga tccagaacga aacatgcagg tctataacga tattgaggaa aaagtcactt
    49261 ctctttccga aaccggtgtg gagaacattg atctagagac cctcatttca aaagatgtgg
    49321 atgcttattt ccagacatat gtcaaagaat tgactaaaag ttcgattccc aaagatcttt
    49381 tgccagatga aatctggcgg ttaaccaatc aattgtatga tgtggctgaa aaacggttag
    49441 accgtattta taatgaaaaa gctcgttttg cttttgcttt gcatctgcaa agtacattgg
    49501 atcgtgtgag agaaggtcat atgatcgtcc acccagattt gaataacgta cggaaaaatt
    49561 ttaagaggga attccaggta gcaatcgatc tttcaacgat cattgaagaa gaagaacaag
    49621 ttgagattcc ttttgatgaa atcggcttta ttagtatgtt tctttctatc aatctaggag
    49681 aaagtgagcc tgttaaagaa aacaaagtag atgttctcat attgatgcac ggcagacaga
    49741 ctgcttcaag catgttggag atggcacaag aactattagg aacaaaagta gggaaagctt
    49801 ttaatatgcc actggttatg gaagttcaaa caatgtatga agaagtgtta caatatgtca
    49861 aaaactatca agagcatttg acgaatggcc tactcttgtt aacagatatg ggatcattaa
    49921 acaccttcag tgatttgatt tatgaagaga ctggcattcg gacgaaagct atcacgatga
    49981 caagtaccat gattgtgata gaagcgatac ggatggcaag tgttggaaga agcttagaag
    50041 atatttatca aaatatccag ctttcctttg aatcgatcgt acgtgatcag ttcaaagcgg
    50101 aaaagtctga aactttacag cgtaaaaaag ccgtaatcgt gacatgcttt actggtgaag
    50161 gagtagctgc caaattatat cagcgtatta tgccagtgat taatcaaaat aaggtagaac
    50221 tgatccagat gcagttttta gaacgtgaat cattcaaaaa acacatcgat gccttattgg
    50281 aagaatatga gatcaaagca attgcgggaa cagttgatgt tgattatcaa aatatcccat
    50341 ttttttcagc ctatgacgtt tttgatgatg aaaaactaaa tattttaaag cgtatagctg
    50401 atgatgagat cccgacagct aaaattgtcg attcacttgc tggatcatta agcgatgtct
    50461 tttctattga tgaactgatc cgttcattgc aaaagacagt tcagcagatc cagaccgatt
    50521 tgtcgattat cgtggaacct ggagtagata ctggaatcgt tatccattta gccttcatgt
    50581 tagacggatt gatcaaacaa gaaagccatc ggcaatttga gaaactgtct attttctcaa
    50641 aaatttatcg tttggaaatg gatatcgttc gggcaaactt gatggcacta gaacgaaaat
    50701 atcaggtaaa aattccagaa gatgatatcg catttcttac acaaatgttt cttgaaaata
    50761 aaataaaaaa atgaacacac taatcatact gtttacacac taaacatctg tgtgcgcact
    50821 ataaaaaaga gctaaaaagc atgaaaacgc tatttcagct ctttttttta ttggcatgct
    50881 tcttgcgtta tataaaagtg taaaaaaata aaaggagtgt taaaaatggc aaaaaaaaca
    50941 atcatgttag tttgttcagc agggatgagt acgagtttat tggtcacaaa aatgcaaaaa
    51001 gcagcagaag aaaaagggat ggaagccgat atttttgcgg tctctgcctc agatgcagat
    51061 aataatttag aatctaagaa tgtcgatgta ttattattag gtcctcaagt acgtttcatg
    51121 aaagctcaat ttgaacaaaa acttgcgcct aaaggtattc cattagatgt catcaatatg
    51181 caagactatg gcatgatgaa cggagaaaaa gttcttgcac aagcagaaaa tctaatgaaa
    51241 taaatcaagt atgcagttgg gggtataaca acgtggaaga tcaacaaaat ctagaagcca
    51301 tcatggggtt aatcatgttt ggcggtaatg caaagagcga tgcaatggaa gcgattgcgg
    51361 ctgctaaaat cggtgatttt gagttagcgg ataggaaaat cgctgatgca gaagaatcac
    51421 ttatacaagc gcatcatgca caaacagaca tgttgacaca agaagcacaa ggaaatcata
    51481 tgcaagtgac attattgact gttcacagtc aagatcactt aatgacatct attgcgttta
    51541 ctgatttagc aaaagaaatc atcgaacttt atcgtcgcgt atacagcgaa taaatacaac
    51601 ttcttttttg aacggaagaa gaaaaatttt tgaacggatt ttttattttg ttataaggag
    51661 aactctcttt atataaaaaa cttataggag gaagtaaaaa atgaacggac tatcaagttg
    51721 gatggagaaa tacatcctgc cggttgccgc aaaaatcgga gcgcaaaaac atttagttgc
    51781 tttgcgtgat gcttttatcg gcatactgcc cgcaacaatg gcgggatcag tcgctgtaat
    51841 gatcaatgca attattcgtg atttaccgca acagtttaac agtacctatg ctgacagttt
    51901 agcagcagac aaaggaatct ttgccgtatt gaatgtcatc atcggaatca atggttttgt
    51961 ctggaacggt acactagcaa tcgccggatt gatctttgcc ttttcttggg ggtataatct
    52021 tgcccgagct tatggagtaa atgatctagc tggggggatc gttggtttag ctaccttgat
    52081 tcaaggtatt tcctttggtc cagcattatc agcagcatta gatgtgaatg ttccttcaaa
    52141 tgtcgcagat gcaatcaata gttctgagat tggtgcaacg attgcagatg gcacactgtc
    52201 agttggatta tggggttggc taaaactaga tcatttgaat ggaaacgctt attttacagt
    52261 tatgatcatg ggagctattt cagtcattat tttttgtaaa ttgatgcttg ccaacattac
    52321 gatcaaaatg cctgattcag taccaccagc agtatctaaa gcatttgcag ccattttacc
    52381 agcgacgatc gctttatacg tcattgctat tatcaattat atcgtaggtc gtgtagctga
    52441 tgggcaactg atcattgatt tggtgcaaaa atatattgca gaaccattcc tagggttatc
    52501 tcaagggttg ggagcagtat tgatcgtcac agtatttgtt caagtattct ggttctttgg
    52561 tattcatgga tcaaatgtat tggcaccagt gctagaggga atctggggac aagcacaact
    52621 aatcaatatt gatattttcc aaaaaggtta taacggaaaa actggtacac cagccgtgtt
    52681 agatgcaatc gaagatggaa aagcttatat gtgggtccgc ggatcgttcg atgcttttgc
    52741 atggtttggc ggatcaggcg gaacgatcgt cttactgata gctatcttga ttttctctaa
    52801 acgtgcagat tatctaacag tagctaaatt atccattggg cctggtatct tcaatatcaa
    52861 cgaaccagtg atgtttggtc tgccaatcgt attgaatgca atcatgttta tcccattctt
    52921 gattgctcca gtagtagcaa cagcaattgg atggacagct acttatcttg gcctagtcgc
    52981 tccggtatcg cagcaagtca catgggtagt accgccgttc ttattgtcat tcttagcaac
    53041 aggagcggat tggcgggcac cgatcgtaac attagtatgt atggtcgtga ctttcttgat
    53101 ttgggcacca tttgtcatct ctgcaaacaa aatggaccct gccgcaggcg aacaacaata
    53161 agatgaacgt gaggagcggg acgctttaag tttcgttcct cataatgaat tttcgaggag
    53221 gaactgaaat gattacaatt gccagtgcaa tgcaacaaga tgaaatcaaa gaattgttag
    53281 aaggatacaa tgaagaagga atgactttta catttaaaga aaaacaagga atcaagctgt
    53341 tctttgaaac aagtgcagaa gatccggaag ttgcggctaa aaaagcaaag gaactaatca
    53401 aagcacagcc ttggggaaca gtcctttatt ttcaatcaac agctgtttag aaaatggttt
    53461 aaaaagatag gatggttgag atgataaaaa acggtttatt tttatgtagt attggttctt
    53521 tgatcgtgtt gtatagtttg aatccacatt cgcaaaggta tgatttgtat agtatggtca
    53581 caggtctttt tctaacagga ttaggaatct atttcttcat gaaggggaaa aaaagagaag
    53641 aagcaaagga gaaaaataac taatggaaat cacgaaaaaa ttaaatattc cagcatcgtt
    53701 tttttacgat aaagttatgg actctgtcct tttcgatgta cgtaaagcga ccggcaaatc
    53761 agtaactaga aaacagctga aaaatttgga gtacgtcaaa caattctcgc aaaataaccg
    53821 ggctcgcata aaaatcgaag aagtcattga aaaccagtct tataagtttc gtacatcgac
    53881 aacgaagaat gaattcgtcg ttcattatca aatcaaacca ttggacgatt cgacctgtga
    53941 ggttcattac acagaaaaaa tggagtctta tggcatgctt caaaagttga atgatatgct
    54001 tttaggaaca atcttgatgt attttaaacg gagacgtttc aaaaaaatgc tagatatgat
    54061 cgaagcaacg tattaaatca atgaaacatg gtactattta gttattgaaa aatgaagtaa
    54121 gctagaagga atttttcata ggaagataga tctttcctgc gaatcctcac tagctttttt
    54181 gtaggaaggg gcagcaaaat gacaaacaaa gtaagagagc taggtgtatc ttcgattgag
    54241 gaaatgtttg atttagccac ttatgcattt aatggggcag atacacctga aaggcgagaa
    54301 cgttttcgta cacttgcgga gaattcttgg aattacggat tttttgatga ggaggatcgg
    54361 ctaacaagtc aagtcatggc gacccctttt ccagtgaatt tttacggaca agagtaccta
    54421 atggccggca ttggctatgt tgcttcttat ccagaagcaa ggggacaagg cgggatcaat
    54481 cagatcatgg aaaagatcct tgaagattgc cgtgatcgta aagtaagctt atcttatctg
    54541 gcgccattct cctatccctt ctatcggcgc tatggctatg aacaatcatt tgataaaatc
    54601 agttatcaac taaacagtcg tgatgtgccg tttatcaaaa aaaaatctgg aaaaataaag
    54661 cgtatggatt ttgaagatgc aaaagctgca atcagaagaa tttatgaaca gatgccggaa
    54721 aaccaacgag ctggtctgaa gcgcgaagac tggtggtata cgtataaatt caagcaaaaa
    54781 ggcaattacc agtttgcttt gcattttgat gataatgagg aagcaacggg atatatcgtt
    54841 tatcagcttg caacgtcttc ctttattatt gcggagtggg gatttttgga tcatgatgct
    54901 ttttgcagcc ttgttcgctt cgtaagttct cacaatggtg cttttgaaac atttgaatat
    54961 tcatgcggct acggcggtaa tgatcaaaat tatctattag aaaatccatt tgcttctgta
    55021 atgatcacac cttatatgat ggcgaggatc gtagatattt ctttgttttt ggaaaattat
    55081 ccatttaaaa agagacaagc tgcatttgcc ctacaaatag aagaagatca ttatgcgaaa
    55141 tggaatgaag gaatcgtgga agtaacaatc gaaaatggaa aaaatcatct ctcaaaagta
    55201 gaacaaacaa aactcccaat cgttcgagga agtatccaac atatcacgca gctattatta
    55261 gggtatcgta aagtggaaga gttggtattc caagaaagaa tacaggtgac aaaagaatat
    55321 gaagaaacgt taagctcaat cttgccacag caacagccaa ttcttaatga ctatttttga
    55381 taaaaaacgg gtgatgacaa tatttttgtc accacccttt tgtttttcat ttggcatttg
    55441 aaggaaaatg ttaaagtaaa tcctcttttt tcgtaaattt gaattttttg ttttcttttg
    55501 ttttagggtt ttcttttttg tggtcttgga ttgcttcttt cgtaatcttt tcccgatttt
    55561 ttttagatga atctaagcgt tctgcgtata ctttttcttt tggcttatca ttcattggaa
    55621 aggacctccc tacattattt cattctacct ctagtttatc atctgttaag gactagtgga
    55681 aacgttttgc ctaacttata agctgatttt tttagcagat aagcttgcaa gtaaaaaaca
    55741 aacaagctac aattgattta ttgaaattgt tcctgtagct cagtaggata gagcaatcgc
    55801 ctcctaagcg ataggtcgct ggttcaattc cagtcaggaa cgtataaata acccctgtat
    55861 cctttgcggt acaggggttt gttttgtatt tgtgccaaaa atgtgccaaa ctagttatca
    55921 tttttatata aactatcgaa cacagtattg attttttctt tatcctgatc ttcaagctct
    55981 cgaacaatat gaagataagt agacattgta gtttctaaac tgctatgtcc taaacgtttc
    56041 gatacgctaa gtatatttac tccttgataa agtaaaatag atgcatgtgt atgccttagt
    56101 ccatgcaaag taaattgctt ttcaatccct aattctttta attttttgcg caaatatttg
    56161 ctgacggcgt ttgatgaaac taatccattt tttaagttga aaaaaacaaa attatgaggg
    56221 tttttgattt caaaattctc gaataattct ttttgattga ttttaaactt ttttaagaga
    56281 tcaatcgtat gtttatcaat ggaaattttc ctatttgaag tttcgttttt tgtttttccc
    56341 cattcattta atttataatt ccatgtttta ttaatagtga tgatttgatc ttcgaaatcg
    56401 atatcttccc atgttaatcc tagaagttca gcaaatcgca ttccagtggc accagcaact
    56461 aacacgagca taggagaaga gtactgcgca gaaaggtttt cttctacgag tttcattaaa
    56521 gatttaaatt gatcataatc taaatattta tcttcttttg gcttcaatga atcttttcct
    56581 ttgattactg cttttctagt tggatcaaac ggaattaatc cttcttctac ggcatctttc
    56641 aacgacgctc taatatggtt attaaactta ataacggtag attttacatg gtctttagca
    56701 tacttattta aaaagcgttg atatcccact ctatctaaat cagaaatcaa taccgctggc
    56761 atatatttct ttatgttcat taacgtatct tcgtattttc tataagtgat aggagatact
    56821 gttccttctt tataaagttg catccaatcc tcaaagtaat ctgataataa tagatttttg
    56881 cgatcccctt taaggccttt gttcaagtta tattctaatt cgttggcggc atcttttgct
    56941 tctccttttg tcttaaatcc tgattttctt atcttcgtgt attttccgtc atcttttttg
    57001 tatgaaattt cgtattgcca actatttcca cgtttgacta atcttgccat aattgaatca
    57061 gctctctttc tctgatacaa taggaactat aaagaagccc attgtttggg ttttattatt
    57121 ttttgcacat cctttttgct tgccggcgca aggatgtgct atttgtcgtt ttaatggtat
    57181 aattggatgt gtattagatc atccaatcag aggtgtttat tatgattaaa gtgattttta
    57241 aaagaataac tgaacttcca gagtttagat tatttgttga ttattggtat gtctggtttt
    57301 ttattgttgc attgctgata ggtctagatg tcatattaga aagaaaactt aagtaagagt
    57361 tgagttaata aattgaattc ctaaatgaga tattttgtag cccatatttt gtttgccgac
    57421 atcacctaat actatggagc taatcgtttt ttctaacaga ccaaaatcag ataatctatt
    57481 taagctacca tctattagct cttgtgaata gccagacatg ctgatatttc cagtgaaatt
    57541 ttcgtttcca cgactcatta agcatgctaa caattgaatc tcaatcgatg ttaattgatt
    57601 cagtacaaga agataatact cctcgttatc ccatgaagcg ttgttaattc gaagtaaaca
    57661 attcttataa agatttttat acatatctat tttattttgt gcctttgatt tttctacctc
    57721 gtcatttatc ccttcgaata ttccaatgag ttggtccttg ttctctaagt tgaaaacatc
    57781 ttctggaatt tgatcgcgaa tgttttctaa tgattcgttt aaatttttgt agaatttctc
    57841 gatgcgtttg aaacgcttct cgtttttaga cccaaaataa agtgactgca caacgccacc
    57901 aatataagga attgctccaa taccgccttc aactattaat tcaagatatt cttttttggt
    57961 tagtttttca ttgctattat ccatagttac ctcctatttt gtcatttcct ttacaagcat
    58021 tgtgactcct gatggcactc ttttgtatag gttttattat tgtgcacaat ctaactctta
    58081 gtggggcgtg gttcatttat tttttactta ctttactatt aatcatatcc cattgagcat
    58141 aggatttttc tatgttcgat cctcttgaac taatttctcc tgtaaaagtt actttatcgc
    58201 cctttgtaaa ggtatcagca ttgtttaagt ccttcgcaaa aattacatat gaaactttag
    58261 gtgttgcaga aatatcattc caacttttat catcgtactc tttgtctgct ataatggcta
    58321 ttctagtagt cattgattcg ataacagttc cttcaaaagt atatgtttta ccactaatat
    58381 atttagtaaa agctgtattt tgctcagtag ctggagtaat agaataataa ctatctaaga
    58441 aagcacccca gtcatgatta tttgtctcta aaaattcttc aaattgagtt aggcttttat
    58501 tgctgctgtt agatgtagta gtttgagtat cagatgatga gctttcctgt ttgttattgt
    58561 catttgcctc gtttgatgag gaaagcgaga aacctacggt agtaaaaata atcccgataa
    58621 taaggagaat cataggtgtt ttcttatttg tttttttgat aaatcttaca attaacatga
    58681 ttaaacctat aataaataaa acaataccag taaaaccaaa tataccgtcc attaatagat
    58741 cctctttctc ttttgatatt gaatattata aaccaagcaa ttcttttttc ttaaaatcga
    58801 attcttcttg attaataatc ccttcatcta acaactcttt atacttttta atttcatctg
    58861 cacttgaaat ttgtgtttct ttggaattat tatctaatat agattgttgc ttctctatat
    58921 atttttttaa attttccatt tcattccaat atttttttgt aaacataacg gtgttttcat
    58981 ctttcgtggc cgctaatata cctccgcgac tttcgtttcc gcctagcaag gtaaattgta
    59041 tataaccatt actcatacct ggttttttta attgtacggc tgatatattt ttaaagggga
    59101 tagttttttc tcctttaata ccttgattaa ctaaatttat aaatcctttt ctaataattg
    59161 aaatagaatc atcagttact ttaatcaagg tttttcctgg agattttatt aaaatctctt
    59221 tttccatttt ttcttcctca tttctgtgat atgatttttt ttgtagaagc tcatatatga
    59281 ggaaagagcc cgtgtt
//
LOCUS       DAZUJR010000007        51594 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.007, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000007 DAZUJR010000000
VERSION     DAZUJR010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51594)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51594)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51594
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.007"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(22..1722)
                     /locus_tag="ACG804_000405"
     CDS             complement(22..1722)
                     /locus_tag="ACG804_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831363.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            2229..3389
                     /locus_tag="ACG804_000406"
     CDS             2229..3389
                     /locus_tag="ACG804_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFS4831364.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            3405..3848
                     /locus_tag="ACG804_000407"
     CDS             3405..3848
                     /locus_tag="ACG804_000407"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4831365.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(4331..4861)
                     /locus_tag="ACG804_000408"
     CDS             complement(4331..4861)
                     /locus_tag="ACG804_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HFS4831366.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            4966..5517
                     /locus_tag="ACG804_000409"
     CDS             4966..5517
                     /locus_tag="ACG804_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFS4831367.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(5670..6143)
                     /locus_tag="ACG804_000410"
     CDS             complement(5670..6143)
                     /locus_tag="ACG804_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFS4831368.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            6281..7753
                     /locus_tag="ACG804_000411"
     CDS             6281..7753
                     /locus_tag="ACG804_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HFS4831369.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            7750..8460
                     /locus_tag="ACG804_000412"
     CDS             7750..8460
                     /locus_tag="ACG804_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HFS4831370.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            8812..9096
                     /locus_tag="ACG804_000413"
     CDS             8812..9096
                     /locus_tag="ACG804_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HFS4831371.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(9413..9796)
                     /locus_tag="ACG804_000414"
     CDS             complement(9413..9796)
                     /locus_tag="ACG804_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HFS4831372.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIK"
     gene            complement(9798..10382)
                     /locus_tag="ACG804_000415"
     CDS             complement(9798..10382)
                     /locus_tag="ACG804_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HFS4831373.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(10429..11904)
                     /locus_tag="ACG804_000416"
     CDS             complement(10429..11904)
                     /locus_tag="ACG804_000416"
                     /EC_number="4.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HFS4831374.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            12085..12396
                     /locus_tag="ACG804_000417"
     CDS             12085..12396
                     /locus_tag="ACG804_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831375.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(12511..14847)
                     /locus_tag="ACG804_000418"
     CDS             complement(12511..14847)
                     /locus_tag="ACG804_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HFS4831376.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            14989..15657
                     /locus_tag="ACG804_000419"
     CDS             14989..15657
                     /locus_tag="ACG804_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFS4831377.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            15660..16703
                     /locus_tag="ACG804_000420"
     CDS             15660..16703
                     /locus_tag="ACG804_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFS4831378.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(16940..17821)
                     /locus_tag="ACG804_000421"
     CDS             complement(16940..17821)
                     /locus_tag="ACG804_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFS4831379.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            17980..18708
                     /locus_tag="ACG804_000422"
     CDS             17980..18708
                     /locus_tag="ACG804_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HFS4831380.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            18864..19181
                     /locus_tag="ACG804_000423"
     CDS             18864..19181
                     /locus_tag="ACG804_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFS4831381.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            19174..19782
                     /locus_tag="ACG804_000424"
     CDS             19174..19782
                     /locus_tag="ACG804_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HFS4831382.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            19837..20628
                     /locus_tag="ACG804_000425"
     CDS             19837..20628
                     /locus_tag="ACG804_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="HFS4831383.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            20766..21254
                     /locus_tag="ACG804_000426"
     CDS             20766..21254
                     /locus_tag="ACG804_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HFS4831384.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            21305..22177
                     /locus_tag="ACG804_000427"
     CDS             21305..22177
                     /locus_tag="ACG804_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFS4831385.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            22353..22715
                     /locus_tag="ACG804_000428"
     CDS             22353..22715
                     /locus_tag="ACG804_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFS4831386.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            22724..23476
                     /locus_tag="ACG804_000429"
     CDS             22724..23476
                     /locus_tag="ACG804_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4831387.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            23490..25292
                     /locus_tag="ACG804_000430"
     CDS             23490..25292
                     /locus_tag="ACG804_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4831388.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            25569..26609
                     /locus_tag="ACG804_000431"
     CDS             25569..26609
                     /locus_tag="ACG804_000431"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFS4831389.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(26661..28805)
                     /locus_tag="ACG804_000432"
     CDS             complement(26661..28805)
                     /locus_tag="ACG804_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFS4831390.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(29162..30535)
                     /locus_tag="ACG804_000433"
     CDS             complement(29162..30535)
                     /locus_tag="ACG804_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFS4831391.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(30535..30930)
                     /gene="rbsD"
                     /locus_tag="ACG804_000434"
     CDS             complement(30535..30930)
                     /gene="rbsD"
                     /locus_tag="ACG804_000434"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016872 - intramolecular lyase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HFS4831392.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(30958..31875)
                     /gene="rbsK"
                     /locus_tag="ACG804_000435"
     CDS             complement(30958..31875)
                     /gene="rbsK"
                     /locus_tag="ACG804_000435"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006014 - D-ribose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HFS4831393.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(31983..32996)
                     /locus_tag="ACG804_000436"
     CDS             complement(31983..32996)
                     /locus_tag="ACG804_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HFS4831394.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(33077..33676)
                     /locus_tag="ACG804_000437"
     CDS             complement(33077..33676)
                     /locus_tag="ACG804_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HFS4831395.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            33862..34563
                     /locus_tag="ACG804_000438"
     CDS             33862..34563
                     /locus_tag="ACG804_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4831396.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            34573..37284
                     /locus_tag="ACG804_000439"
     CDS             34573..37284
                     /locus_tag="ACG804_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFS4831397.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            37735..39363
                     /gene="treC"
                     /locus_tag="ACG804_000440"
     CDS             37735..39363
                     /gene="treC"
                     /locus_tag="ACG804_000440"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HFS4831398.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(39423..40604)
                     /locus_tag="ACG804_000441"
     CDS             complement(39423..40604)
                     /locus_tag="ACG804_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFS4831399.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            40856..42379
                     /locus_tag="ACG804_000442"
     CDS             40856..42379
                     /locus_tag="ACG804_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HFS4831400.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(42448..43176)
                     /locus_tag="ACG804_000443"
     CDS             complement(42448..43176)
                     /locus_tag="ACG804_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFS4831401.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(43189..44469)
                     /locus_tag="ACG804_000444"
     CDS             complement(43189..44469)
                     /locus_tag="ACG804_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFS4831402.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(44610..45212)
                     /locus_tag="ACG804_000445"
     CDS             complement(44610..45212)
                     /locus_tag="ACG804_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HFS4831403.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            45457..45663
                     /locus_tag="ACG804_000446"
     CDS             45457..45663
                     /locus_tag="ACG804_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831404.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            45975..46694
                     /locus_tag="ACG804_000447"
     CDS             45975..46694
                     /locus_tag="ACG804_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFS4831405.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(46775..47458)
                     /locus_tag="ACG804_000448"
     CDS             complement(46775..47458)
                     /locus_tag="ACG804_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HFS4831406.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            47677..49863
                     /locus_tag="ACG804_000449"
     CDS             47677..49863
                     /locus_tag="ACG804_000449"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HFS4831407.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            50209..50619
                     /locus_tag="ACG804_000450"
     CDS             50209..50619
                     /locus_tag="ACG804_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFS4831408.1"
                     /translation="MIKVYTSPSCTSCRKARAWLKANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            50633..50989
                     /locus_tag="ACG804_000451"
     CDS             50633..50989
                     /locus_tag="ACG804_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFS4831409.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT        16852 a         9073 c        10262 g        15407 t
ORIGIN      
        1 ggatgtattt atcccttttg cctaagcacg taaaagcttg tatctatgat aaataaataa
       61 acatagcaag gtaaaccagc caatcaaagt aagagaaaga atgaaataga aatagattgg
      121 cgtttgataa tgaagcgtga gctcgttgat tcctttttgc tgcttcacga ttggggtccc
      181 gatatctgtt acttcataat cagtcaatgt ttttccattt tgctgtagca cagtccgatc
      241 gtagacgata acagggatat gaacagtttt gtccccagtg tttttccact tgattgtcaa
      301 aagaccgcct ggatgtgttt ttataaaagt tgtttcgttt tctagtattt cttcgttata
      361 ccggtcgtat ttattgtctt ttgtctcctt atagattggc agatagtcag gtgtggtttt
      421 ttggaaaacg aacaagctgg tagacatatc tttgctgaag aatgttttcc ttgcttcttc
      481 cggcgtatcg aatagataag tatgtcgact gacaaatgtt tcattttccc acttttccag
      541 atgctggtat aagttctgga tcgtctgtgc tgaaaaaata agaatgccaa atatacttaa
      601 aagacggaac cacttttgtt cagaccactg gttcagtgaa agggcaaggt aaagtagaag
      661 caatagcgta aatggcacga aaaatcgaaa tggaaactgg atcaaactaa taaaaggcac
      721 atttttttcg atcaatgtcg tccatggaat caagctagta gaaagaaaaa agaaaacaag
      781 acttgtgtac aacacgattt tttggaataa ggtgttcttt tgttgaaaga aaataaaaag
      841 caaaaaacct gataatatca atataggaaa ggccttaggg taatggagcc aataactgcc
      901 atccagatct atcgcctttt gactcatttc tctgttaaca aagggaggaa gaatcttatt
      961 cccactgtaa acaatagcta atcctgccca aatatttgct gtcagaacaa aataaagcaa
     1021 gaccgactta atcagttgaa gcagtgcttt tcctttttca gtctggttaa aaaagtaata
     1081 aagataaaaa gggatataca tcaaagctaa catgatcgaa gacagtaaat ggatctgtgt
     1141 cataagtccc actgagacag cgactttgat aacagggaac tttttatgaa ggacgaaatc
     1201 agcaataggg atcatacata aaggataaaa acaagtcccc cagctagtga atccttggtt
     1261 gatagaccag tattgaatag aatacgtact catgaataaa acggctactg gtacacttac
     1321 ccaatttcga acattgacat atctcagtaa aatcagcata gaaaatcctg aaataagata
     1381 aagaatgaaa tttgaaagaa tctgataatg aaaccagcta cctgcaagca acacgatcaa
     1441 tccttgtaaa taagcgaaaa atgggccgta aacggcattc acgatcctgc cactttgctg
     1501 gaatccataa agggaaggaa aataatggaa atccccatat ttaatttgtt gcgcggcatc
     1561 atagaaccga ttgtaatgga atggggcatc agcacccaaa attagtttat gtgtgaataa
     1621 atgaggcatg agaaatgcca aagcaatgaa aaaaattgct aaaaatgggc catatttttt
     1681 caattgtcga actcctttgc aaactttaga taaattcatc atatatccta tgcgagaggt
     1741 aggcaagaaa ttagaaaatt catgaaaata tttatgaatt ttacaagaaa aacataagtg
     1801 aaagttctaa ggagagagga tgcgacataa gttttgttgc atctccttgt tttgaaacag
     1861 aatttttctt aatactcgaa acaaagtagc tttttcatga cctctcggta aacggtgttc
     1921 aatcagctgc ttctcggtaa taagctcact agcctagaaa atatgagaag ctattttctg
     1981 actagcgctc ttattactca aagcataacg cagttttcac aacctcttcc ttaaacggtg
     2041 ttcaaaagct tgcatctgcg gtaataagcc caacccaaca aaaaatatga gtagctattt
     2101 ttttgggctg tacttattac ttgatgcagg acagcttttt cacaacctca tcggctttca
     2161 ttttctattt ttttcctgaa cccatataat aaaagaaaga acaaaaaaac ttgcaaggga
     2221 ggacacatgt gaagcagagt aagcaaaaac agtctcgtcg acttttgttt cgtttgtttt
     2281 tattaatatg tatcgtcgta gggttactga tcgctttata tccattttat gtggattctt
     2341 taaatagttt tattgatcaa aaacgtatcg aacaagtaca aaaacggacc gcagctgaaa
     2401 ttgaagtgca gcgaaagaaa atggaggaga aaaaccaacg attaactgac caaggattca
     2461 atcctggtac tgatcctttc aatgaaaaga acagaaatga aagtacaaca tccagccaat
     2521 tagaggaatg gctgatcgga agtatcaata tacctaagat ccaattaaat atttcacttt
     2581 atgatcggct caatggtagg atccttgaaa atggagcagg cgtcttgcaa ggaacctctt
     2641 tcccgcttgg tggaaattcg acgcattcag tgatctctgc tcacagcggt ttacctaatc
     2701 gacggttatt taccgaatta gatcgtttag aaaacggaga cacgtttatt ttgactgttt
     2761 tgggggagaa attggcttat caagttaaaa atatacaagt ggtactgcca gatgacacgt
     2821 ctgttctaac gatttcagaa ggagaagact tagttacctt gcttacatgt acgccgtata
     2881 tgatcaacac gcatcgtttg ctagtgacag gacatcggat tccttataac gaatcggtaa
     2941 aaaaagaaga aggaaaagga aatcaggaaa gaaccatgcg gcaatggttt attcttgcag
     3001 gaacgataat agctgtagtc atactgttag tgtttatcgg acgactaatc tatcagtata
     3061 gattaagtaa aaaagtgctt gatttttcat ttattattag tgattcgtca gggaaaccgg
     3121 taaatggtag ttcattcatt ttgaaacata agaaaaaaac acttactaga aatggtgtgc
     3181 cgttttcagt acaaagcgac catcatggga aagtcaagct ggatcaattg cctggtggaa
     3241 cttatcgaat cgtttcagct gatgatccta aagttgctgt ttcttttggt attagaaaag
     3301 taaaacaaga gaagatatac ttttttgagg ggcgaaaact tgtaaaagag cttcaaaaaa
     3361 atggttttta ttttaaaatc aatgaataag taaggagaga aaaaatgatc cgcacaacaa
     3421 caaaattgtc tgccaaagaa ctggaatctg ttctatcgat ttggctgcat gctaacttgg
     3481 attctcatga attcattcca tcaacttatt gggagaatca agtagaatct gttaggaaag
     3541 ctttaccaga tgcagtgatt tacttagcag aaatagatca agaaattatt ggttttgctg
     3601 gggtgattga tcagtttatc gcaggaatct ttgtgaaaag ggaataccgg caacaaagaa
     3661 tcggtacgca actaatgaaa aaaataaaag aaaccaataa aacactgact ttgacagtct
     3721 atcaaaaaaa tcaatcagct attcatttct atctttcaca aggttttaca attcaaacac
     3781 agcaaaaaga tgaagcagta aatgaggagg aacttgtgat gaaatggaat caaaacgctg
     3841 atttttgatg aacagaataa cgaaataatg ctcccagcct aattttttgc tgggagcatt
     3901 atttcatttt gaagtcacta atttaactgt gtgaatatgc agttgttaca atctttgata
     3961 aacggtgttc aatcagctga ccctcggtat tagctcaaaa aacggcaaaa tatgaggaac
     4021 tatttttcca tttgtttctc taatactcag gtcaaaacgc tgatttcaca acctcttgat
     4081 aaacggtgtt caaacggctg cttctcggta ataagcccac tagcctagaa aatatgaaaa
     4141 gctattttct aactagcgtt cttattactc aaagcataac gctgatttca caacctcttg
     4201 ataaacggtg ttcaatcagc tgaccctcgg tattagctca aaaaacggca aaacatgagg
     4261 aactattttt ccgtttcttt ctctaatact caggtcagaa cgctgatttc acaacctctc
     4321 tttcacaacc ttattttact cgtttataat tttcatcgaa gtattttccg ctacggatat
     4381 catctggcat tccatcgtat ggttcttcgc taataacatc ttcattgtct atacctgcat
     4441 cacccatata agtgatcgta gcaaattcag gaacaagtaa ttttggataa gtttcatatt
     4501 tttcacgagc tgcttccatt tctgcgatat gttcgttttg gaaagtaaca gtgatttctg
     4561 gatgttcttc aacccattta gggaaaaaga tcattccgtg aagtttcttt tcatttggca
     4621 taaagtccaa tgccacgtct gtccctgttg gctctgtcca agtgattttg aatacgccgt
     4681 ccgtcaattt aacgatatca gcttcttggt cttttaccca acggcctttg accattccgc
     4741 catggatacg gtaatcaaca gtatggtcat ttttggcata ccattcatat tcccaaccat
     4801 tgtcatacgt atagataaag tgagttccaa taaaatcttc caattcttta aattctttca
     4861 tgtttaagca tctccttata aattaaaaca tgtaataaac tacatgtttt cgattactca
     4921 tttatgatag aatggattta aagatttgtc aaggagggaa aactgatggc aagaaaaaat
     4981 acacttcgat atattttgtt agggttatta agtaagaaga agatgacagg atatgaattg
     5041 aatcaatcgt tcaaaaatga aataggagaa ttttggcaag caaaacatag tcagatttat
     5101 cctgaacttg caaaaatgga agagcaagga atcattcagc atcaagtaga gatcacaggt
     5161 gaaaaattgg aaaagaaagt ttatgaatta acagaagaag ggaaggaaca attggcagag
     5221 tggattcata cacccaccaa tgaactaccg gttaatcgag acgaatttgt tctgaaattg
     5281 tatttcgtca aagacgtgaa tgatccggca ttagtagaaa ttattcagca gcagcgtgac
     5341 cttcatgaag aaaaacgact tcatctatta gagcgaaaaa aaacgatctt tcctactgaa
     5401 aaagaaaaac atgaaaatta cggacactac ctgattttag cgcatgcgat caatcgggaa
     5461 acagaatatg caaattggct aacagatgta ttagaagaaa gtaaccgaaa aaaataaaaa
     5521 aatatccgaa cagtgatgga gaattccttt ctatatgaaa gaaacgcaga tcaccgttcg
     5581 gatattctta tgttcaaaca ggcctttttt caagtattta tgtagcatct acttattaaa
     5641 aagcttggta cttaggagat tagtggcgtt tagagttctt ttaacaactg ttcgtagtca
     5701 gctttttcat cgacaggaag gagcttgtaa gttaattcgt ctgtctcgtt gtcatgaatg
     5761 atgtacatct tagcattctc ttctttgaag ttaccgattt gtaaaatcgt atagcgttcg
     5821 tcgatcaatt cgatatcttt gattgctttt gaaaaaactt tacggacatg gtgcattttc
     5881 ttttggcgga tttctgcctt ttctgcagct tttgacaaag taaatccgtc atctaaatat
     5941 tttttgatca gttctacttt tatgactgta ggtaaacgat attttctagg acaattcgca
     6001 tcagcttcga tcgaacgaat gaatcccttt tgttcccaat accttaattg acgtggagac
     6061 acacctacga tatcacttaa ttcactgatg ccaacaacca attgatcatt ttccaacaaa
     6121 cgtttaaggg aagccccaac catttttgtc actccttttg tcctcttgct tcccttaatt
     6181 atatccgtat taacttatgt gtcaagtagg ttgacaaata gcgaatttag gactaaagta
     6241 ttctagtagt ttcagaaaaa attcagaaag aaggagaaat atgagtaaca accaacccgt
     6301 agatatttac ggaaaaccat ataatcggac acttttagtt gttgtcttat taattggtac
     6361 attttgtacc gttttgaatc agaccttatt gacgacagct tttcctacat tgatgaaagc
     6421 tttcgatatt tcagcgtctg atgtgcaatg gttaacgact ggtttcttgc tagtcaacgg
     6481 gatcatgatc ccaataacag catggctgat caataaattc agttcaagaa atttatatct
     6541 ttctgccatg acgatctttt tgatcggaac gattacttgc tttacagcac ctaattttag
     6601 tacattacta atcggtcgtt tgatccaagc ttgcggtgtg ggagtatcga tgccattatt
     6661 gcaaaatatc atgctatcta ttttcccgcc agaaaaaaga ggatcagcaa tggggatgtc
     6721 agggatcgtt attggacttg ctcctgcttt aggccctaca ttatctggtt atatcattga
     6781 taactaccat tggcgtgact tgtttggtat ggtactgcca atcgttgttc ttgtcttggt
     6841 tttagcattc ttcctaatga aaagtgttat tccattgtca aatcctagca ttgatatttt
     6901 atccgctatt ttatcaacga ttggattcgg tagtttactt tacggatttt ctagtgtagg
     6961 agatgacggc tggggaagct tgaaagtaat tggtttctta gttgttggtg tgattttcat
     7021 cgccttgttc tcatggcgtc aattacattt ggaacatcca ttcttggaac ttcgtgtatt
     7081 caaatcatct acattcacga ttgcagctgt tttagctggt gtaacaaata tggcgatggt
     7141 aggggcagaa atggtcgtac cattgtatat tcaaaatatt cgtggagaat cagcattcca
     7201 ttctggcttg atgttgttgc cgggtgcatt gatcatgggg gctatgatgc ctgtgacggg
     7261 tgcgattttc gataaatacg gcgcgaaacg tttagccatc acagggatgt tcattttgac
     7321 agcggcaact gcaccatttg ctttcttgac aaaaacgact ccagttttat atatcgtgat
     7381 cctttatgcg atccgtatgt ttgggatctc catggtcatg atgccggtaa cgacttctgg
     7441 tatgaatgca ttgccaaata acttgatcag tcatgggaca gcggtaaata atacattccg
     7501 tcaaatcgca agctcgattg gtacagctat tttgatcagt gtgttgacga atgtgacaaa
     7561 agcaaatatc ccaagcaaat ctgtattgga taatacgcca ttagcttata aagatcaggc
     7621 aatcaatgcc acactgtcag gttaccatgc cgcgtttatc gtagcgatca tctttgggat
     7681 tcttggcttt attattgcct ttttattgaa gaaaaaagaa cctgttctaa tgaaagcggg
     7741 ggataatgca tgattattgg agttttgatt gtcagcttgc ttgcttttgc tttaacgaac
     7801 gtgttcgcta aaaaaacatg gcaaaccttt ttatctttga ttttcggact aatcttcgtc
     7861 gcttcactaa gtttgatcgt cgctaatttg tccaatcact ttggaatgga aaaagtaacg
     7921 gaaacaaaaa cagaaaaaat tgtttccagt gctgattccc aaggagcaga tatgcttttg
     7981 tataaagctt tagggaatgg aaaagaaaaa gtgtatcttt accgaacaaa tgaaaaacaa
     8041 gaaaaaccaa aagcaactgg tacggataac gaaacaaata aagtagaaaa gacagacggc
     8101 gatgctgaaa aagtgacgaa aactacttat tgggaataca aaaacgacat gtataaattc
     8161 tggttcaata ttgctgataa caatcacgaa tatgacagcc gagtgaatac attcaaaatc
     8221 ccagagacat gggtagaatt aagtacggac caagcagcca agttagctga attagtgaag
     8281 aaacagcaaa gtacgatgga aagtgaagca aaagcttatg ttcaagacgg tatggtaaaa
     8341 gcaatgactg aaaatccaaa aatgagcaaa gcagagcaag aacaacgtac gaaagcctta
     8401 gctgctgaat tccaacaaca agcattcgca aaattagtga aagaagcaaa aggcgaataa
     8461 tattttgaac accatgtagg aggttgtgaa aaagctgctc tgcatcaagc agtaagaaca
     8521 atcagataaa aatagcactc catatttttc atctgattgg gcttagtgcc gtagatgcaa
     8581 gcttttgaac accgtttaag gaagaggttg tgagcctgcc gtttaactct gagtcacaag
     8641 gagcaatttc aaaaaacagc ttctcatgtt tgttgactat tgtgacttgt gaccgaggag
     8701 ttggcaggag aacaccgttt attcgaaaaa aggaactgcg acaagacttt tgtcacagtt
     8761 ccttcttttt tttgctatgc tatactagat gtaaaaaata ggagaaataa aatgagggaa
     8821 atttattctt ttgaatcaaa aatctatgct tccgaagtcg gcaagggcgg ggcatatatt
     8881 atttttccgt atgatataag aaaagaattc ggtgctggaa gagttaaagt ccaagcaact
     8941 tttgacaatg tgccgtatga aggcagtatc gtgaatatgg gcgtgaaaaa tccagatggt
     9001 tcagtctgct acatccttgg actacgaaaa gatattcgta aaaacatcgg aaaagaaatc
     9061 ggtgatattg tagcagttac agtgaagcaa aaataaaaga ggttgtgaca aaagacgtgt
     9121 cacaacctct tgataaacgg tgttcaaaag ccagtttctc ggtagtaagt caaatttatg
     9181 caaaaatgtg gaaacccatg tttacaaaat ttttcttact actcgaaacg aagcggcttt
     9241 atcacaacct cttgataaac ggcgttcaat cagctgtccc tcggtattag ctcaaaaacg
     9301 gcaaaatatg agaagctatt tttccatttt tttctctcat actcaggtca taacgctgat
     9361 ttcacaacct cttctttcat aatggttttt caccatcttt ataataaact ggttatttga
     9421 tatggaaatc tattttttcc aaccaatcta aaatcttgta acctaactct tctgacatcg
     9481 gaaaagaggc gttgatttgt gcattggaga tatggtcaac atggataccg gaagtgatcg
     9541 tacaacttcc cggaacggca gttttgatga tcacagctat tttttcggct aagacatcgt
     9601 ctttatggaa ccgaccatcg tggctaggga aacgtacagt ttgcatctct gtatcacgag
     9661 aaaatgtagt gactgttccg atatgtggtg tatctccgcc tgttaaagtg atcaataagt
     9721 ctttaccgat tactttaaca gcagcttgga tcgtgaaacc tagtttggtt acttcaacta
     9781 tcgtttcttt ttccatatta atcaccctgc caacgttttg aatgctcatt tacaatttca
     9841 aattgatcca aaagtttcat tgtatggtga ttaacaagat cttggatcgt ttgaggctga
     9901 ttataaaaag caggaattgg tggtatgatt tgcacaccta gtcgtgctaa tttagtcaag
     9961 ttttccaagt gaatggcatt taatggcgtt tcacgaggaa caatgactaa ctttcgttgc
    10021 tccttcattg ttacatcagc agcacgtgca atcaggttgt cgcctaaacc aacagagata
    10081 cctgcgactg ttttcatact tgccggtacg atgatcattc catcggtcaa aaatgatccg
    10141 ctggcgacag cagcacctaa atctttgttt gaataatggt aatcaaacag gctttcgaat
    10201 tcagttagtg ataagtcgga ttccagcttt aagttctgtt ttgcccatgg actgatgatt
    10261 ccgtgtgttt ctatcatcgg atattctttt agtttcttca ctaggttgat ggcataaatg
    10321 gtgcctgaag cgccacttac accaatcacg atttttttct tccgttgtgc caattgttcc
    10381 attttccgca ctccttttta tgatgtcaaa acagttgcag atcattcatt atttcaaata
    10441 tttttcccaa tcttctactt cttggaattt tgcacgtaca aaatgttctt tcatatcgaa
    10501 aggaactgta ccgtcaaaga tagtttttgc acttatccca cggaaacgaa tagagccagg
    10561 attatattct ggtaattctg atgggtccaa tggatggttc ctcattcctg ggatcacgat
    10621 gatatcttta tctccttgga aacgagtgtt gaaagtccaa actacatcgt tcatgtcgaa
    10681 aatatcaaca tcttcatcga ctaaaatgac tgtcttcaat tctttgaagg ctgataaagc
    10741 aagaatagct gcttgacgct gaataccttc atccgcttcg ttttctttac ggatttgcat
    10801 gatggtcatc aatttaccac cacctgcagg aggattgtag acatttacta cttttcctgg
    10861 aatagcttta tcgaccaagg caagaatact tgcttctgta ggaataccgg ccatagatac
    10921 gtgttcttca ctgggaccaa tcgttgtttg catgattgga ttgtcttttc ggtgagtaac
    10981 tgctttgact ttcactactt gtacagctgg attagcatcc ccagtatagc caggaaattc
    11041 tggcattgct tttcctgagt tcgtgttgat atcttcttgc attgtttcat ttggcatgat
    11101 ttctgcttca atgatgaatt cagcacgagc aatacccact tcatcgactg ctataccatc
    11161 aacgatttga ataggttcgt tacgcaaagc tcctgcacac catagttcat tgtagccaag
    11221 tggagtggta ggtggttcga aagtcgtgcc aatggcaatt gctggatcta aaccaatatt
    11281 gatagtgata ggcattggtt tattcaaggc ttcgaattgt ttttggaagt gaccaatgtg
    11341 gcgtccgcca ggcatgatgt acataccgat cgtatcttta tcttctagaa ccatacgatg
    11401 gatcgttaca tcgctcattg ttttttctgg atctgatcct aagactacac ccattgtgat
    11461 gtatggacca gcatcttcag gagtatttgt aggtgcaggc aaaatgttgc gaatatcgaa
    11521 gtctgcatcg gtagctagat gaacgacttc ttgtgctgga gcgtctgctt tgtctacttt
    11581 cacaggtttg attggatttt ctacagcgtc tttcaagaaa cgaccaagtg ttcgataatc
    11641 atggtgcaaa atttcaccta cacgtttacg actagccatt gttccgatgt tcacacgtgt
    11701 gccggggaaa cctttgatat tgttgaaagt catagctggt ccttcttgag tcggacgttt
    11761 tactgtaccg ccagcaccga tataacggta aacaccagat aattctgctt caggatcgat
    11821 ttcaatatct gtttcgtgat attgacctgg aagtgttttt agttcttcga tgacttttct
    11881 taaatcatac ggttgatctg tcatgagaga ttcctcctta gttgtcttta cctatctata
    11941 gtaaaaggtg aaaaagagga aaacaattca acttgttcgg taaagtattc tacaatggaa
    12001 tggatgcgtt tttttgataa tagaataaac tatgatatac ttatcactaa aagaaagcgc
    12061 atacttagtg ttggaggaag gaaagtgaaa aaaatggagg agtcatttcc taaagcagta
    12121 aaagtggaaa atatagcgaa tattttgaaa gttacatttg aaaacggaga agtaaaatac
    12181 gtgaaatctc attggacaga agagataacc gatgccttgc aatttggaaa aaaaggaaga
    12241 ggaaaaagaa aaaatcttct cgcactttct cgtaatatgt ggattgggac tgaagtaacg
    12301 attgaagcag atggaacagt attcataaat ggaaaagaca ggtatacgcc agaagagttg
    12361 tggtacaaag gaaagaaaag tataccagaa ttataaaaaa taattaaaaa aaacagcgcg
    12421 aaacaaggaa catattactt cctcgtttct tgctgttttc tactatttca gcgctcttat
    12481 gactcaaatc taaatgtggt tgtcacaacc ttattctgca cgcaaagcga tagcggcgtc
    12541 ttttttcgct gccattcgtg caggaagatg accgccaagc atcgtcaata tagtagagac
    12601 gatcactaga ataatcgcat ggacaggatt tagttgagca acatttttta gatccgtcat
    12661 gttgtataag atgctattga tagggaacgt agctagccat gcaataaaca cacctaatat
    12721 cccagaagaa atacctaaaa tacacgtttc tgcgtcaaat acgcgagtga tgtctttttt
    12781 acgtgcacct aaagctttta gtacaccgat ttcttttgtc cgttcaatca cagatgtata
    12841 agtaatgata ctgatcatga tcatacttgt tactaaagag atccctgcaa aagcaataag
    12901 gacataagtg atagcatcca tcaatccgcc agtcagttca gtcatcgttc cagctaaatc
    12961 agtataaatg attttatctt catctgattt gcctttattg taatcatcta gataatccaa
    13021 gatcttttct ttgtcttcaa aattgttcgg ataaatcatg atacttgaag gcaagctgtc
    13081 tccacctaaa taactaagca atgtttgttt ggcattttcg tcaacttttt cagtagttaa
    13141 gacatttaca ccactgtctc tttgagcttt gacgatttct gattctttgt tttcgttgac
    13201 gatttgagtc gttaattgat cgctataagc gattcctgga gataagagat tcattgtaga
    13261 agaagatttc acgcgtagga tccccgagat cttcaattca tcagaagcat tctgatacat
    13321 cgcatcataa tctgtattag ggataaaatt cccagttgga agttttgtat agtaagtatt
    13381 gttgtttact aatttgaatg ttgtaccaac gatatcatca aaatcaagtt tttcgtcttc
    13441 tttcacatca aatccaagat tcttcaatgc gttgatatta gtattattat tgccgtctac
    13501 gatcagcacg acatctgttg ctgaggctgg ataacttccg gcaagtaaag aataattgtc
    13561 ttttaaaaag ttttctttgc tagtgtcaag ctgtgtaggg aaacttgaca ctcccacacc
    13621 tgtcattgct gacatcgtac tagataaaga aagagattcc gtatcaggat tttgattcga
    13681 gaagctgaca ggctgtactt tgccatttac atcacgtaaa agattgattc ctgtagtacg
    13741 ggtaaatccg atattattac ttaagttagg atcgatgtct gttacgtaat cgacgtatgt
    13801 ttgatcaatc ttattcgtgt gctgtgcttt atcttcttcg ctgacttttg cagtaatcgt
    13861 tttgctgtct ggataatccg ctttgcttgc acccaatccg gcatcgtcac gagtctggtt
    13921 agtcgttacc ttagaaatag taatcggaaa tttcgccatc gtttcagctt gcgtgttatc
    13981 gatttgtttt tggaatccag aagaaaggga cagaacgatc gcgattccga tgatcccaat
    14041 actggaagca aaggaggtca agaaagtacg tccttttttt gttcggatat tgttgaagga
    14101 aagctttaac gctgtccaaa aactcatctt tgttctgcgt aagttaaatt gatcatcttt
    14161 tggtcgttcg atgtgaggat gggaatctgt taagatctta ccatcagaaa attcaatgat
    14221 tcgatctgcg tattgatggg ccagttcagg attatgtgtg accatgatca ctaatttttc
    14281 tttcgataac tcttggatca attccatgat ctggatactt gtttctgtat ctaacgctcc
    14341 ggttggttca tcgcacaaaa ggatatctgg gtcattggct agtgctcgag cgatggccac
    14401 tcgctgcatt tgtccaccag ataactgatt tggcttttta tgcatatgat ttgtcaagcc
    14461 gactcggtgc aatgcatctt ctgcccgttt tcgtttttcg tctttagaaa caccacttaa
    14521 tgtcatccca agttcaacgt tttcaataat gcctagatga ccaatcaagt tgtaactttg
    14581 aaaaatgaaa ccgatagagt tgtttcggta ggcatcccag tcactgtcct taaagtcttt
    14641 agtagacttt ccgttgatta ccatatcacc ggaatcataa ttatctagtc caccaatcac
    14701 attcagcata gtcgttttac cagaaccact aggacctaaa atcgctacga attctttttg
    14761 tctgaaagcg acagacacac catccaatgc tttggtggtg gtttcgccga ctttataata
    14821 tttttttata tcttttaatt gaagcataat cacccttctc ccgtattgaa atattcggta
    14881 tactaataag tatatcagaa caatgatcgt agtatacgaa ataaatgtta actgaagatg
    14941 aactacaaga aaaaatctag aaatttttca aaaaacagag ggagatcaat gaatcgtatt
    15001 ttagtagtag aagatgatcc gcaattacag ttgctttacc gttctgtgtt ggaacgagcg
    15061 ggcttttcag tcatcaccgc attgaatgga gaggatgcgc tgaaaaaact agaagcgaca
    15121 cgtatagaat taatcattac agatatcatg atgccgaaaa tggatggcta tgacttgcta
    15181 gactcattac gtagcaccag atttgacaca cctgttctaa tgattacggc aaaggccgat
    15241 tttgaggata agaaacgcgg gttcaaatta ggagcagatg attatatgac aaaacccatc
    15301 gatgtcaatg agatgatcct acgtgtggaa gcattgcttc gacgttcaaa gatcaattac
    15361 agcagtagct tgataatcgg acaaacaaaa ttagagctag atgcttatac agtgttacaa
    15421 gatcagcatt cgttgattct gcctcaaaaa gaatttctgc ttctgtataa attactgtct
    15481 tatcccaaca agatcttcac tcgccaacag ttgatggatg atatttgggg attagatacg
    15541 aatacagaag aacgaacgat cgatgtacat atcaaacgtt taaggacccg ttttgaaaag
    15601 acggaagatt ttcaaatcat cacagtacgg ggactaggct ataaggcggt tatttaaaga
    15661 tgaaaaaaaa gctattttca caattatgga tctattttgc tagtattgtc ttcatttcga
    15721 tcttagtgac actgctgtgt tttctcggtt ttattttctt attgtctcga cattctatct
    15781 cgcctgctga atcggctgga aaaccaacgt tatacccgtt attcgtcttt gcggggttca
    15841 gtatggtcgt gggtacagga atatcgattt ttgttgggcg gcgtatcctg catccaatca
    15901 gtgcgctagg gacaaatatg agtctggtag caacgggaga tttttcgatt cgaatggatg
    15961 aacagcagaa agtagcagaa gtacagcaac tgtataaaga tttcaacgtt atggtccaag
    16021 aactcaatag tatcgagaca ctgaggaatg actttgtgtc cagtgtatcc catgaattca
    16081 aaacaccact agcaacaatc caaggatatg ttcaattgtt acaagcccca aatctctctg
    16141 acgaagaacg ccaaatattt ttatatcgga ttatcgaaag tatcacgcag ctttcacaat
    16201 taacagagaa catcttaaaa ttgaacaaac tggaaaacca gcgtatccaa ctggaaaaga
    16261 aagagtatcg attagatgaa caaatcagag aagtaatcgt tttttttcag cctaaatggg
    16321 agaaagaaca gctagaattg gatatcgaac ttgctgcagt aaattacaca ggcaatgaag
    16381 agtttttgta ccaagtgtgg ctgaatatca tggataacgc cataaagtac aatcaaatca
    16441 atggacagat tcatatcaaa ctatttgaga cagccacaga gattgtactg gaagtgaccg
    16501 attcaggtgt aggaatgaat gaagagacca gagatcgaat gtttgaaaaa ttttatcaag
    16561 gagatacaag tcgtcaaatt tctgggaatg ggctaggact ttcactggtt aaaaaaattc
    16621 tagaactgca tgatggacgt attgattata gcagtatcga aggagtagga acgacagcaa
    16681 tgatacggtt aagtaaacaa taggaaaaag aataaaaccc ctaaaaattc tattgaaggt
    16741 ttttaggggt ttttagtcgt ttttttgtga ttagggaaat gttcttacgg ttcttttggc
    16801 ataaaaatcg ctgctttctt attgaactac gagaaatgtt agaggtgtca ttgaaacaag
    16861 gacatgatgc aagaaagaga gcgaaagtca tgcgtcgctc tctttttttg ggtggataga
    16921 tggacagaaa atgtagggct tagttttctt cttgatttaa atactcccaa aatgtatctg
    16981 aagccaaaga atgctcaccg actttacgag taaatgcaag ataactctct gttgttggag
    17041 aaatagggag aatcacagta ttttctttta atagattctt gactgttttt tccataacaa
    17101 tagcaatccc catgtcattt gcaatcatat tgatgatcaa gtcgattctt gctcctttat
    17161 aagagatttt tggttcaaat ccagcttcgc gacacagatc tagtacaggt tgatacaagt
    17221 tcgtagtggg gccaaggagc aaaaagttct cctttttcag ttcgcttaga tccaatttct
    17281 ttttactagc taaaggatga tttttaggta gaactgctac aaaatcgtct gtttcagtag
    17341 gcaaccactc aatcgaactt ggtggggcct ggaaacttct agcaaagtgg atcgtgtcac
    17401 tatgttcatt ggcgtcattg taagttaatt cgacactttc cacttctttc aactggactg
    17461 taaattcagg atggcgtttc aaaaactcgg tgattttgga aaaaccttta taattgatca
    17521 ttgtcggtat cgttaagata tttaatgaaa gattgttgtc tttcgtatag gtttcaagca
    17581 cttcttgcat agcatggtat tgttctacga cattttttac atatgggagc aataagcttc
    17641 cagcttcggt caattcgatt tttctatggg cgcgttcgaa taatttgacg tctaattctg
    17701 tttctaacga aagaatctgt ttagaaatat ttccttgggt ggtgaattgt cgatcagcag
    17761 ttttggtgaa attcattgtt tcggctaaat caagaaaaac ttcgaattta tggatatcca
    17821 tcatattcct cctacttatt ccaataaaga atactttaac acaaaaaatg aattggtgta
    17881 atcttctctg tctgttacaa tctttcttgc agcgaaagca ataattacag aaatttttct
    17941 gatttttttc gcttcgtaga aaaagagagg agttttttga tgccaactgg agttttgatc
    18001 aatgtaggtt ccgttttgtt tggcggacta attggcggat tagtaggaaa taaattaagt
    18061 gaacatttta aagcacagct gacgatggtt tttggtgtgt gttcgatggg gatgggaatc
    18121 tattccattg cgccgatgaa aaatatgccg gctgttattt ttgctttagt gataggaaca
    18181 gcgattggtt tgattgttca tttaggtaat gggataaata agggggctgc gctgatgcaa
    18241 gtacctattt ctaaaatctt ccctagtgaa aagcttggta tgacccacga tgaatttatc
    18301 agcacattag tgacggtcat tgttctattt tgtgcaagtg gtacggggat ctatggaagt
    18361 ttagattctg ggatgacagg agacagtacg attttgattt ctaaatctgt ccttgatttt
    18421 ttcacagcag ctatttttgc gtgtaattta gggtatgtcg tttctgtgat agcaattccc
    18481 caattcatta ttttttatat tttgttctta ttggcaaaat ttatttatcc attgactaca
    18541 ccagacatga tcttagattt taaagcttgc ggcggattct tgatggtcgc taccggtttt
    18601 agaatgatca acgtgaaaat gttcccagta gctgacatga tacctgcaat gatcgttatc
    18661 atgccactga gctggatgtg gacaaattgg attatgccac tgttataata aaaatcaaag
    18721 agaagccatt ttttgctgac taaaaaggat caaatctttt agtcagtttt tttgtatttg
    18781 acaaactgat tttgaaacta tattatatgt tgtataatat agattgaaat aaaatattac
    18841 acttgagaat agaaggtgac gtaatgcaca tccagattcc aactgttctt cttgatggta
    18901 ctgtgctagc agcattaagc aaggaagata tgtatgggta tgccttaaca aaaatcgtac
    18961 aagaaagtct ctctgtcagt gaatctacac tatatccggt tttgagaaga ttgaaaaaag
    19021 aaggatatct tgagacctat gatgaacctt ttgaaggcag aaaccgtcga tattactcgt
    19081 tgacaccaat gggaagtcgt catttagaag aaattattga tgaatggatt gtttttcgag
    19141 attctttaga ccggttattg gaggagagca caaatgaatg aatatttgaa tgaagttgtg
    19201 gatcatcttc aagaaattcc tgaagacgat cgttttgatt tgatccagta ttatgaggaa
    19261 tattttttag attctggaaa aacattagat cagatcattg atgaatatgg tacaccaaag
    19321 cagtttgcct taaaattaaa aatcagttac ttttcagaag aagaacaagc agaaaacgag
    19381 ttagtgaaaa atccaaaaag acaaattcgc ctgatttggt taatcattat cggtttattt
    19441 gcttctcctg tcctcattcc actagcactg gggtttatat tggttattgg gggactattg
    19501 gttgctttac tagcgctcat ttttagtatc tatgttttat gtatcagtat cttaggtgtt
    19561 ggcctattca tgatcatctc aggaatcagt gtgtttggac aatcgattct gagtggatta
    19621 ttctttatcg gtgtcggtct gttcgccaca ggaagcgcag tatttatttc gccactgttg
    19681 ctgaaaggaa caaaagggct tttttatgtc atgatgaact ttgttaaatg gatgggacga
    19741 cgttttatta caaaaagaga tctgcattca gcgggcgttt gaaggaggac acataaattg
    19801 agattgaaac attttttgat taccggtatt ggtctgatgc ttactggtgg cctcctagca
    19861 ggtgcaactt atacattagg cgctcaaaag agtctgactt gggataatgg tcctcggttg
    19921 atcgatatgg ttactgagac aaaaaaaatc aaggatgcaa acaaaatcgt catccatgca
    19981 gaaaatcaaa cagtttcggt catacgcgga ttggattttg agataaaaac gacttatgat
    20041 aagacagaaa agccagaaat aaaggagaaa aatggcgtgt tgactgtgaa tgcagtcaaa
    20101 aaatcaacag gtgcaatcat tagtttagaa gacacaagtg cacaaatcac tattgttgtc
    20161 cctgcagatc atgaattatc tgaattgaca atcgaaggga ataatagtgc aattgatatc
    20221 aacgaagtat caatcaaaaa agtgaatact aagacacatg atggctgggt atcgttcaat
    20281 gaatttacag gaggaacaat aactgcgaaa gatgaattag gctcacttcg attagatgag
    20341 gccaatgtgg ataacttgat cgtcacaggt gaaaacagca acttccatct agaagacagt
    20401 ttgatcagca aagaaggaaa agtcatccta aacggtggca atttatcttt gcatgagatg
    20461 gaaaacagtg gctatactat ccaaacgtct ggtgaatctt atattgaaaa agactaccag
    20521 ccaataacaa atactttgtt agaacaagga cagaaaaagc taaagatcac tgctaaagac
    20581 acatcgatca atattacgac ggatcaagag gacaatgaaa cagattgatc ctgtactcaa
    20641 ctggatattt taagaaaaaa cagcaaagat ccttccaatc tttgctgttt ttcatcgctt
    20701 aacgcacata actatagtaa aataagaaag aaaatatcta aaaagaaaac agggtgaaag
    20761 agtatatgaa ggtagaagaa ggtcaaagag aaaagttaaa aacagaaatg gaaagattac
    20821 atacttatat cactcaacta agccaaacct tctatgatcc agacaaagaa aaagtgatgg
    20881 ttaattaccc gaacaattca gaaggtcgcc aattagagca agtgtaccat gaagttttca
    20941 aacatttatt gacggtgaag aaagagctgg attattattc tttaccgatt atcgatacag
    21001 gaatattgaa gtatgatggg aagaaggaac gatttatctt taaatctgtt cgggaagatt
    21061 tgcctctttc agcagggatg gatctagagg tcttggtaga agactatttt acagaagaaa
    21121 agcactgggt tcgaacaaaa ttggattatt taccgcaggc agccggaggg acacaggcaa
    21181 gcggttggta catcactgaa gacaaagagt tagaactaga aggtgtaatg gcgcgtattc
    21241 gaaaaaaaaa ttaaaaaagt aacattagat atttattgaa ggataaagga gcgcaggaag
    21301 tagcatgaga gaaaaaagag cattttatat caatggttat gcagggattg tcggattggt
    21361 cgtattagct ttagttggat tgtttttctt ctatttaggt atgtggcaag cgaaagtttg
    21421 ggcacttttt ttaagtattt ttctttggtt gatcacgtta ttgttgttaa gttcggcaac
    21481 tgtagtcagt cctaatcaag caaaagtaat tttgtttttt ggacaatatt taggtacgat
    21541 tcgagaaaat ggctttttcc ttacgatacc tttggcacaa aaaatgactg tttcgttgaa
    21601 agttcggaat ttcaatagtt ctgttttaaa agtcaatgat ttggatggaa accccatcga
    21661 aatctcagca gtagtagtct ttaaagtcgt tgatacagca aaggcattat tcgatgtagc
    21721 gtattatcaa gattttgtag aaatccaaag tgagacagcc attcggcata tcgctagcca
    21781 atacccgtat gatacattca atgagaatga tttgacgctt cgaggaaaca cgacggcagt
    21841 gtctgacgag ttgcaaaaag agctgcaaga gcgtttagca gtagcaggtg tcgaagtaat
    21901 cgaaacacgc ttgaaccatt tagcctatgc aacagaaatc gctagtgcca tgctccaacg
    21961 tcaacaagca aaagccattt tgtctgctcg acaaaccatt gttgaaggag ctgtcacaat
    22021 cactcaaatg gccttagagc aaatcgaaga tggacaagaa atcaatttca ccgatgatcg
    22081 gaaagtccaa ttgatcaata atttacttgt ctcaatcatt acagacaaag gaacgcaacc
    22141 tgttatcaat acaggcgaca tgaaagaccg taagtgacat actttttgta agataggaag
    22201 aaggagttta ggacggatta ttgtcttgaa ctcttttttt agttgtttta aagaaaatga
    22261 caaaattgaa agaagaatga tagttgattc gaaggcagaa ttgttcgctt ttttctataa
    22321 tcagtatata aagtaagaga gaaggggaaa aagtgaaaaa acttctgatc ggtctacttg
    22381 ttttcatcgt tgtggtactt gcaggggtga aaatcgcaga ttacgtagtt atgggtggag
    22441 aagaatacta tgtacaaatt acgacagatg gtacaaaaac agtttcaaaa tcagactctg
    22501 gacaagaaac agtcaactat agatatatcc tgcctggcta tacgaaagag ggtaaggaaa
    22561 aagaactgga cttcaaggga caattgactc gaccgcttcg taaaggagca tatttaaaaa
    22621 tcacctggaa caaaaataaa ggtgtcactt cgtatgaaga agtcgaaaaa aaagacgtgc
    22681 cgaaaacagc actggaaaaa ctaattaaag ggtagggaaa gaaatgaaca aaatagtcga
    22741 agtacagaat gtaacaaaag tatacggaaa aaacaatgag aaaaagacgc aagcattaag
    22801 cggcatcagc ttcgatgtag aaaaaggcga atttattggg atcatgggcg cttctggttc
    22861 tggtaagtcg acacttttga atattttatc cacattagat aaaccaacag atgggcatat
    22921 ccgaatcaat caaaaagatg tgaccacatt aaaaggaaat caactagcag attttcgtgc
    22981 gaatgagatt ggctttattt tccaagattt caatttatta gaaagcttga cagcacaaga
    23041 aaatatcgct gttcctcttt ctttacaagg cgtcagacca aaagaaatca agcaacgtgt
    23101 ccaaaaaatt gcagaacgtt tatccatctc tcatattttg gaaagctatc cttctgagat
    23161 ttccggtgga caaaaacaac gggtcgccgc cgcacgtgca ttgatcacac aaccaacgat
    23221 tctattaggg gatgagccta caggtgcgct ggattccaaa agtgcccggg atcttttaga
    23281 tacgatggac gaattgaata caaaagatca tgtatcgatt cttcttgtga cgcatgatcc
    23341 gttttctgca agttattgcc aacgtatttt attcatcaag gatggcggta tccatcaaga
    23401 agtgaaacgt ggagatcaaa gccgtgattc cttctatcga gaaatactat ctattcttgg
    23461 aaacttggaa cagtaggggg agattgacta tgctttggaa attatcactt actgggatca
    23521 agagccgttt aagagactac ttggtgttat tctcaggatt agttatggca tctgctattt
    23581 tttacatgtt tgaatcaatg gcaagcaacg aagctttttt gaaaagtaat acgatcgttg
    23641 cggctacagt tatcattttc cgattcggtt ctgttttact agggatcatc acattcgttt
    23701 atattttata tgcaaattcc tttttgatga cgatgcggca aaaagactat gcaatgttta
    23761 tgatgctggg agcaaaaggc agaaaaatcg cacagatgat tttttctgaa acattcttag
    23821 tagggatcgc agctacttta gtgggttcag ctgtcggtgt aggattgaca agtatcgtcc
    23881 accgattatt agtggatcag ttagatctca atatttcgca ttttacacct tttagtattc
    23941 acgggttgtt gatcactgtt ttgttttttg ctgttttgtt tttattagct gctgttgtca
    24001 atgctttttc gattgtcaaa aaaccgattt tagcattgat tcgtgcggat cagacaccaa
    24061 caagaatcaa gcagcataaa ttcttgtttt tccttgaagt agtactggga attgcttttc
    24121 taggctgcgg ttactatatg atgaaacacg tggggaccta tcaagtcttt ggtatagggg
    24181 tagccttagt tacgatcgta ttaggaactt atttcatttt ccattctgtg atcattttct
    24241 ttttatcatt actaaagaaa tcagaacaga tttcattgaa aaaattgaac aatttcacat
    24301 tgtcacagtt aaactttcgt attcgtgaat atacacaaat gctctcaatg gtcgctatgc
    24361 tgtttgcctt ggcactgggc gctttgacgg taggattagg ttttaaaaat gaaattgcag
    24421 acttgacaga aaacaattct ggatatgatc tagtgatgaa taatcctcgg gcagaagatc
    24481 agcaaaaaat caaagaactt tcaccaacac tttctgcttc ttatactcaa aaagaagatg
    24541 cgggaacgat ttactataat gcaagtgaat ttgcggctca accattgatc atgataaaac
    24601 atgaagatgg aacaccgccg aagatcacga aagaaaaagt tcctgctaaa aaaatgaatg
    24661 aactgactgt acaagaggaa cttcgaagct atgaattgcc ggaacagcaa gaaaaagaaa
    24721 tcaaggtagt cagtcaatca gaatttgatc aactgaactt gccacaatcc actttacagc
    24781 tagttcaggt aaaagacttc caagcaaacc tgaaaccaat cgaaacactt gttgctcaaa
    24841 ataaaatgaa caatccatct ttgcaaaaag tagagtacag caaccagaaa tatgaaatgt
    24901 atgaagtgta taatggtcta ttctctggtt ttgaatttat gggattcttc ctaggtttag
    24961 ctttcttgac catgcttgct agctgtttga tgttcaagat cttgtcagga agcaagagtg
    25021 acattgctcg ttatgaaatg cttgaaaaga taggaacacg acgcgggttg cttaaacaat
    25081 cgatccgtag agaagtaggc gtgttattct tagcaccagg aatcttaggt gtagtccatg
    25141 tcttattcgg attacaaatg tttggtctat tcatgcaaaa tccatacaaa gatatttggg
    25201 ttccgtttac gatattcttc gtattgtatt tcatctacta tgtactgacg acatggttat
    25261 atactggaat cgtattgaaa aagagattgt gaaaaagctg tcctgcatca agtaataaga
    25321 acagccaagc aaaaatagct cctcatattt ttcgtttggt tgggcttatt accgcagatg
    25381 caagcttttg aacaccgttt gttcggaaaa agaggttgtg acaatatttt tgtcacaacc
    25441 tttttttcac ggtcttttat tagaatatag taaatttttt ctcgttactc acggaataag
    25501 ctgttaagaa aacggtttcc atgtatactg gaatcagtgc aaatgaaaga aaagagggtg
    25561 caaggaacat ggaaatcaat gaacaaaatt ttggcgaaaa ctatcacttg attacgatca
    25621 cgaatcaaaa tgggacatct ttgtctgtca gtgatcttgg ggcacgggtt gttcattttc
    25681 aaacaataat cgataatgaa aaacgagagt tgatcttagg ttttgatgaa gcaaaagaat
    25741 atctagaaaa agacccttat atcggtgctt caatcggacg tatggctgga cggattacga
    25801 atggcacatt caaattagat gatgaaacgt tcgaagtaaa aacagacccg gacactggtc
    25861 attgtttaca tggtggtgca cctagctttg aagccaagca gtggcattat acagtcatca
    25921 atggtgaaaa cgaagcatcg gtcattttct atcagactag cccagatatg gaaaacggat
    25981 ttcctggaac tttagatgta gaagtacggt atacgctgac gaacgatgat acatggcgag
    26041 tgacggtcca agggatcagt gaccgcaaaa cagtattcaa tcctacaaat catgtctatt
    26101 tcaatttaac cggtgatcca gcacagtcaa tcgacgaaca tatactttgg ttgaatagcc
    26161 gattatttgc tacgctcaat aaagatacaa cgcctacagg agaagtagtt tcagtaagtg
    26221 gcacagcatt tgacttccaa cgtcctaaaa aattaggtga ggtctttgcc agtgattttc
    26281 gccaatcaat gatagtgggc ggcatcgatc atccattttt gttgaaaaaa caatctggtt
    26341 tactaaatgc tgcggaattg acaagcccag atgaaaaagt atcgatccaa gtaaaaacag
    26401 atgcttcagg aatcgtgatt tttacagcaa attttggaga agatggaccg gaaatgcgcg
    26461 ggaataaatt agtaaatcat ggcggtatca catttgagac tcaagaactg ccaggagcgg
    26521 agcgacttga aagttttgga gatgtcactc tggaacctaa ccaagtacgc gagtttgtaa
    26581 cggaatacaa aataaatata aagaaataga ataaattaaa aagggagtgt gacagtgtca
    26641 catccccttt ttaatttatt ctatttcttt aaaggcagat caagccagaa tgatttgtct
    26701 aaacttaaca aggttagtac aggaacagtt gcagctttaa ctgtacgagt agttgtttct
    26761 ggtatctgtc ttgccgtaaa attgttccac aaatcccaga ttgaagcgac acggaagatg
    26821 gaagaagcgt tgttgacgcg ttttatcgtt gaaaattcta atcctgtgat tggcacgcca
    26881 tctgttgtcc atttgattgg cacatcgaat cgcttagaca tattgaggat ttcagcgttt
    26941 gcttcttcag ttgttgctgc ttcttttttc ggttcatcat attttgtcag gtcgtacgct
    27001 tcgatgatcg cgttcaattt ttgtgaatat tggcgatctg tagcataacg tccttccaaa
    27061 tatttggttg cttctttgta gtcttttgtt tccgacttcc aagttggttt gtagaaatca
    27121 ggattgccag tcagtccatt tttgatcaag tcggcatagt cttccaaact ttccttgtaa
    27181 gaaggatatt tacggaattg tgcgcggatt tggtagcttt gtccggaact atcttgttca
    27241 agtgtattga aggtcacgct gcttccttta tatgatcctt tgataccaaa aaggttatga
    27301 tttggttcgc ttgataataa gctgtttcca gatccacttt caaggatagc ttgagccatc
    27361 atgactgatg cgtagattcc ttctttttgc ccgatttcct gtgcatcatc tgcaatcttt
    27421 ttcaagaact gatcagttgt ttggttttga ctgaaatgga acgagccatc taatccatct
    27481 aaaatagatg agccgcctgt cagcgaacct gaagcagcag gtaaacctgc taagtttact
    27541 cggacagcaa aatcaggcgt gaaatctgaa atagaagtta ctcgaacttt atctcctggt
    27601 tgaggcgcat ggataaattg tccgttccca atatagatac ctacatggtg agtaacaccg
    27661 gaagaaggtc cccagaagac gaggtcgcca ggttgggcct gacttactgg aatctgcgta
    27721 cctgcatatt gctgttcgcc tgtccagcca ccgatataat gaccggttgc tttcatatat
    27781 acgtaataag tcaaaccaga acagtcaaaa gtatttggac cttttgctcc ccatacatat
    27841 ggttttccaa gatgcttgaa tgcttctcga acgattgctt gttggacatt cgttgtattt
    27901 gtaggcaata cagcatcaat tggtgatttt acaacaaaat cagaagaagc agaagatgga
    27961 ttctctatac cgctttgatt tgctgtattt ggacgagatg aagcattgtt cgttccgcca
    28021 ttcgatgaac cattgtttgg atggtttggt tctctctgag tatttccatt gttattcgat
    28081 ccagatgggt ttgtttgatt cgaagaattc ccgctgttcg aattattgtt attattgttt
    28141 gaattatttg aaccattatt attgttgtta ttacccacat ctggtttgtt tggcgtttcc
    28201 ggatctggtg tactagggac ttcttcacta ggatcagttg gtttctctgt tgaagtatcc
    28261 ggtccagctt taaattctgc agtaatagat aaattgttcg tacctactgt aaaggtcttt
    28321 gcatcataat ttacttcttt ggcaccatta acagcgactg aagcaatttg ttcaccttca
    28381 gctggcgtaa tagtgtaagt taccttcgtt tccgctaata aaccttctac cgttccactt
    28441 tccgtaatat ccaaaggttg ctgttcaggg gaatccgctg tcgaagcagt cagttggatc
    28501 ttaccaatca aagaaggagc aattgtaagg gaatatgtct cggctggctt ttcattttct
    28561 gatggatcag ccggatcaat ttcagttggc tcggtcgatc ctgttgttga gttagttgtt
    28621 ccagttgggt cttctgtaaa agaatccgtt gtttcactag tagctgagct ggatgtagtc
    28681 gtatctgttg tgactgtttg atcagctatt tgattatcta cggcaaatac ggtattggtc
    28741 gacaaaacag acggagcaat cagccaagta gcagctagca aacgtatcgt ttttttattt
    28801 ttcataataa actagtcctt ttcctttcat tgattttctg tcttattcag cattcattag
    28861 acattttttg gaacagataa tcgtgtcgaa aagctttttc ttttcataaa tctgtctgtg
    28921 tattctaaat aaaacaattt gtaaataagc aacgagcatt cattcgtttt tctttgacgt
    28981 tcattttatt gcatagacca cctttgtttg gggataaaca agtggggata aaaatggtta
    29041 tgcatatgta aattatacca aagtttggaa agtatcacaa aaatttataa aaataatgat
    29101 cctaaaaaga aaaagactga aatatgtgat aaacatctca tacttcagtc tttttcatta
    29161 actattcata agacattagg tcttcatcaa acccgctaac gagagtagtg atcattgcta
    29221 cgactagact aacagccagt cctgctaagt accagaaaaa agtaccggaa atgaatgcag
    29281 gcaatgtggt cagactacca aatacaaaag cgatcgcttt cacttgggca aatcccatta
    29341 cagctccacc agcagctgca ccaatgcaag cagcaacaaa tggttttttc aatgggatcg
    29401 caattccgta aacagttggt tcggtcactc ccgcaagtaa aatcgaagca aaagcagaac
    29461 cggagatcga acgggttttt gaacgtttac ttcgcagaaa tacacctaaa gctgcaccag
    29521 ccattccaaa attggctgct cctgtcaacg gaacgattcg gtcgaaccca taagcagaga
    29581 tattactgat catgacaggg tttacagccc attggatacc aaatattacc aaaatattcc
    29641 aaccaccagc gatgattgcg ccactgatcg gtccgttaat atccatcatc caagtaattg
    29701 cggcagctaa accttcgcca aggtaaacac ccgcaggccc gaataccatt aacgtcaaag
    29761 gaaccgtgat aactaatgaa agtaaaggta caaatactaa ttgcatattt tcgcgaatat
    29821 attttttgag gaatttttca acaaaagaat aaaagaaaat acctaaaatc gccggcatga
    29881 cagtagacgt atactgcatc agtactacag gaatccccag aaaatcagta gctgctttgc
    29941 cactgtctga aagtaaagag gtcagattcg gttcaatcag tgctgcagca atgacagccg
    30001 caatatatcc attcacttta aacgttttgg cagcagaaaa agcaagaaag attggcagaa
    30061 aataaaagac ggcattcgac gcagcagaca aaatatgata agttccgctt gtttcactaa
    30121 gccagccaat cgtagtcgct aaaacaacca gaccttttaa tataccagaa ccggcaaaca
    30181 gcggaatgat cggcgtaaag atttccgata tcaaaccaaa tagtttttcg atcggattta
    30241 gcttttcttt cggagctgaa tgatcgattt gacgcgtcaa ttccttgtaa gcaggagcca
    30301 atccctgatc catgattatt tctgcatatc tatcgagtaa aatgaaatac ttaatggaag
    30361 ggatttgctg ttttaatttt tctgcattgg ctactggctg ttttttcaat ttgatacgaa
    30421 gccgagtcgc acatggaagg acagaatcaa tattgtcttt tcctcccaac tgttcaatca
    30481 gcatatgaat ctgctcggac agtaccatct gttcaggatt cattgtcgtt tccattagaa
    30541 gaccactcca ctcactaata taatattggc gtaaggtgtc atttcgcctg tacgaataaa
    30601 tgcatgacag ttattcaact cttttttcat ttcttcatgt gggataaagc taatcggtgt
    30661 atctggtaac aataatttga ttttttccaa tatttccggg ttcattgtct ttatttcttc
    30721 cgccaattca atcgattgta cctcaagttc ttctaaaacg ttttctaaaa cagataaaaa
    30781 acttggaaga ccgtttgaga cagccaaatc tattttttca gtaccaaagg ggacaggcat
    30841 gcctgcatcc ccgatactta atttatcaaa gtgccccatt tgtgcgatta ctcgtgaaat
    30901 atctgaattg attacttttc cttttttcat gtttgtttct tcctctcatt gttaatttta
    30961 gactgctgat tgttctaaag cttcgcggta agggatagaa ggttgcgcac cataagactg
    31021 cacagcaaca gaagaggcta gatttccata aaggatcgct tctttcaagt tactaaggtc
    31081 tggctgaagt gtgctgctta atgcgccaat aaatgtatca cctgcggctg ttgtgtcaac
    31141 ggcatccact ttaaaagcag ggacgatacc gtgttctttt tctgtatgat agaaagcgcc
    31201 ggcactgcct agtgtaatga ttactgttcc aatacctaat tcatggagtt tttcggctgc
    31261 tgcgaccaaa ctgttatgat ctgtcactct gattcctgta atgatttctg tttctgtttc
    31321 atttggtata atgatatctg tcttttcaag tagttcagta ggaatcgttt cacgagctgg
    31381 tgcaggattc aggatcgttg tttttcctgc gtcttttgca atagaaaaag ctaggatcgt
    31441 cgcatctaag ctactttcaa actgagcaat aataaagtca ctgtttgtaa tcagttgctt
    31501 gttttttagg acttcttgtt catggaaagc attatttgcc cctgcatgga tcaagatact
    31561 attttctcct gctgcgtcta ccataatcat tgcttgtccg gttgtggcgc cttggatttc
    31621 agctatccca gatgtatcga tgttttcttt tgtcagtaga tctaataact gttgtccttc
    31681 gctgtcagcc ccaacgcctc caataaaaga tgtccgtgcg cctgaacgtt tggctgccac
    31741 tgcttggttg gcacctttac ctccgccagc gtgaaaaatc tcatgcgcat gcatcgtttc
    31801 gcctggcttg ggcatgttgg ttaaacgaag ggtagtgtcc atattaatac ttccaattac
    31861 tgtaaccgtg ttcattttac aaacctccaa ctatctcatt tattttgatg ggaaaattat
    31921 tttttaaaac gttttagtaa aacgttttaa tagttcgata aaaatatagc acaccttgaa
    31981 agctatttca agggtgcagt tgaaaatctt ttttctaatc gtacaggtaa tcttttttct
    32041 tcccattctt tttctgggaa ttggatccga tctaacaata acttggcaga tgtttgtccc
    32101 aattcgaaga ttggttgtgc gatcgttgtc agtttcggct tgatatactc gcacatatct
    32161 atattatcat agccaataat gctgtagtct tcagggatgc tttttccagc ttcctctaat
    32221 ccgcgatata atccaaaagc taattcatca tttaaagcaa acacaccagt tgcagcagaa
    32281 tcaagaagtt ctgctgtgat ctggtagcca ccttgttttg agaactgtgt aggtaagagg
    32341 atcagttggt cgtgagggat ttggtaaaca tcaagagcag atttaaaccc ctcaatccga
    32401 gcgtggacat tttccggtgg attttcagga tagacaaggg cgatcgtttg atgtcctaga
    32461 ctaagcaagt gcatgcccgc taggtaacca ccgcgaaaat cgtctgttcg tacggcatca
    32521 ctaaatcctt cagatttttt ctgatccaaa acaatgaagg gccggccttg ttttttcaaa
    32581 ttttcgttga ttgcatctgt agagacagca gaagtcgcga taatgaatcc atccacacct
    32641 cgacgtgtga gctcggctag atattcgatt tctttttgat gatcagaatc agcattacat
    32701 aatatcgtga cgaaattctg cttatacaag atatcctcaa ttcctcgcat cagtgtactg
    32761 aagaatggat tcgtgatatc aggaacgagt acaccaattg ttttcgtttc cttggtaatc
    32821 atttgtctag caaaatagtc aggctgatag cctaattctt ctttggcagc taaaactttc
    32881 tgaacagttt tcggactgaa tttctccgta tttccattta atatcaagga gacagttgtg
    32941 attgaaacgc cggaaagttt agcgacttct ttgattgtga tctttttttt caccatgttc
    33001 atactcctat ctaaatcctg tggttatttt cccatgaaat caaaaagaag taaatgaaaa
    33061 tcacgtgtgc cagtacttat ttgctttgtt ggatagcttc gattatttgt ttcgttgagc
    33121 gtactcgtgc agttttcgga aatatctttt ttatgaacaa ttgatgggat tctttgtcac
    33181 gatcactgca agcatcttca gcaagcacga tatggtaccc gtgttgaaag gcatctaatg
    33241 cagtagcata tacaccgttt gttgtcgcta caccgcttaa aatgatagtt tcgattccac
    33301 gccggcgaag ttgaagatca agagaagtac caaaaaaagc acttggattg tattttgtga
    33361 tagtcaacat attatctgta tctttcaaag aatccttcaa aagtaaatca gtgaattctg
    33421 gaggtacaga agcagtcatt ccacccatat cagtttgttg actcaaataa gggaaagtgg
    33481 agatgtctac gttcactaaa actttcaagg cagcggtacg tttcaatgtt cttactaaca
    33541 aatcattgtt tgtcagaata gatgctgcag tgtgtggaga gagtgtaccg ttatttacga
    33601 tctctttttg catgtcgatc gcgacaaaag cagtttttga taaatcaaaa atcatatttt
    33661 cctttaaatc attcatgatg ttccttcttt caaataacaa tgttttttat gtaagtaaat
    33721 cataaatcgt ttatttgtca actaaattaa aggattcctt tctttagtct agagaaattc
    33781 agtggtaaaa taaataagtg tgagaaaacg cattcgatgc atagatatag cgagaaatat
    33841 cgtgaaaatg gaggaatcag agtgaagtat gtcgaagtaa aaaatgaata caaacgatac
    33901 aaaatgggag aaacgaccat tacagcaaat gacgatattt ctttttcaat tgaaaaaggc
    33961 gaattagtga ttatacttgg tccaagtgga gcaggaaagt caacgattct taatatttta
    34021 ggtgggatgg atacacctga tgaaggtcag atcattattg atgacacaga tattgcgcaa
    34081 ttttcagata aacagcttac tgcttaccga cgaacagatg tagggttcgt tttccaattc
    34141 tacaatctcg ttcctaatct aacagcaaaa gaaaatgtgg aattggcaac ggaagtttct
    34201 cctgatgcgc ttgatcctgt agaggtattg aggcaagtgg gcctagctca tcgattgaat
    34261 aactttccgt cccaattatc aggaggcgaa cagcagaggg tttcaattgc tcgtgcacta
    34321 gctaaaaatc ccaaacttct tttatgtgat gaaccgacag gcgcgctgga ttttgaaacg
    34381 ggcaagcaag tattgaaatt attgcaaaac gctagcagac aacacggcaa taccgttttg
    34441 atcattacac ataattctgc tttagcgccc atcgctgata gagtcattca cattaatgat
    34501 gctaaagtaa ggtctgttga attaaatgat catccttcat ccattgatga gattgtatgg
    34561 tagggggatt ttatgaaaac aagaacatat cttaaagcag gttttcgcga aattcggcaa
    34621 tctaaaggac gattcattgc aatcatcctt attgtcatgc taggaacact tttatttgta
    34681 ggtgtcaaaa ctgctggacc tgtcatgcaa aaaacgatgg atcactatgt tggtacagca
    34741 ggactttctg atttgcaaat cgtttctact ggtggcttga cacaaaaaga tattgctcaa
    34801 gcagaaaaga tcccagatgc aaaagtagaa acaggaaaac agatctatta ttccaatact
    34861 ggcaaaaacg aagtgattca aatattttct tataacaaaa ataacaagca gaacaagcta
    34921 caattaactg atggaaaact cccggaaaaa ccaaaccagc ttgtattgga tgaaaaagcg
    34981 gaagatgaag ggtataaaat cggtgatatt tatcagattg attcagatga attgaaagaa
    35041 aaagagtata ccatcacggg ctttgtccgt tctccattgt tcatcaacaa tttggagaga
    35101 ggatacgcga acgtcggaaa tggtagcgtc gattattttg tctatttacc tgaatccgtt
    35161 tttaaaacag atatttattc tgtcttatat cttgatttta caaacgtaaa gaatttgaat
    35221 acgtacagca aagcttacaa agataaaatg gagcaaaatc aagaaaaggc agaaaagtat
    35281 ttacaagatc gacccgaaga acgcttagaa gagctgaaaa aatcggccaa cgaagaatta
    35341 gaaccggcac agcaaaaaat agcggatggc aaagcacaaa caacgcaagc aagaacacgg
    35401 ttagaagatg ctaaaaaaca gttagcgcaa cagtcagcaa ctatccagca gcttcctgaa
    35461 gcgcaacgaa caatcgctgt tcaaacatta tctcaacaag aagctcaact tgctgaacaa
    35521 gaaaggcaat tagttgagaa agaacgtgaa ctggcctctg cagaggaaga attgaatcga
    35581 aatgcagaaa aaattgaaaa tttaactaaa ccatcatacc tatacaatga acgttcagaa
    35641 aatgtcggtt ttcaagaatt tggtgatctg tctgatcgta tcgctgcgat tgccaatgtt
    35701 tttcctgttt tctttttctt tattgccgca ttgatcacct ttacgacaat gacacgtatg
    35761 gtagaagaaa accgcaggga aatcgggaca ttaaaggcgt taggttatac gaaagttgaa
    35821 atcgcaaaaa aatatgcaat ctatgcaagt ctagcctcag ggataggtat tgttttagga
    35881 acgatattag gaacgaatct tttgccaagg atcatttttg agctgtctaa cgagcggtat
    35941 gatattggga gtgcgcttat tttttatgac tggccgccga ttttacaagc agctgccgca
    36001 ttcttcattg ccgcatttgg cgctgcaatg atcgttttat tcaaagattt aagagaacgg
    36061 cctgctgcat tgcttcaacc gaaagcaccg aagccaggga aacgcatttt tcttgaatac
    36121 atcactccgc tgtggtcacg ccttagcttt aatcaaaaaa tcagttaccg aaatctcttc
    36181 cgatataagt caagaatgct tatggcgatt atcggaattg ctggatgtgc cgggctgatg
    36241 gttgcaggcg tgggattgaa agattctcta agttctgttt cagccaaaca atttggaccg
    36301 atcattgact atcaagcaat cgttacattg gattcatcca cggaagatag tcgtcaaaaa
    36361 gcagcggata tgctgcagaa gcaagaaaaa gtaaatgaga tcctagctat tcatactcaa
    36421 accgtagaat tgagaaaaaa aggacatgct tcgcaaagtc tgacagtgat cgtaccaagt
    36481 aaaacagctg atttggatcg ttttatccat ttaactgatc ttgaagagaa cccacgctcc
    36541 ttgcctaaaa caggaatcgc tattacgcaa aaagtagcag aactatttga cttatctaca
    36601 ggagatcata tttcgcttta tgatgaagat caaaaagaat ggaaagtcga agtaaaagaa
    36661 atcgtgaaaa actatctagg tagctttatt tatatgtccc ctgaatatta tgcttcagtt
    36721 actgatcaat cgatgatgga taatgcattt ttgctgcgta cagataagat gacaacaaaa
    36781 gaagaagaaa tgctttccga gaaactgctt gccacagacg ctgtgacaaa tacgtctttc
    36841 atgtccaaac aaatcgaaac gcaagaagaa tcaatggcga acttagactc ggttgtctta
    36901 atctttgtcg tattatcagg actgctggct tttatcgtct tgtataatct aactaatatc
    36961 aatatttccg agcgtgtacg cgaattatct acaataaaag tccttggatt ttttgataaa
    37021 gaagtcacga tgtacattgt tcgagaaaat atcatcttta ctcttttagg aatcatcgga
    37081 ggatttggtg taggatatat attgactgac ttcatcttgc aacaagcgtc tatggagaat
    37141 gtcatctttc cattagtgat cacatggtgg gcttatgtct tatcagcagg attaactatc
    37201 gtatttacgg ttattgtgat gattgttacc catttcaaat taaagcatat cgatatgatt
    37261 gatgcgttga aatcgaatga ataaaaacag aggttgtgaa atcagcggtt tgacctgagt
    37321 attagagaaa caaacggcaa aatagttttt catattttgc cgttttttga gctaataccg
    37381 aaggacagct gattgaacac catgaatcag aggttgtaaa aaagccgtcc tgcatcgagc
    37441 aaaaagaata ctcaaataaa attagctcct catgttttac atttgagaag actgattgcc
    37501 gtagataaaa gcttttgaac accatttata gaagaaacaa gaatattttg ctattttaaa
    37561 caagaggata gacaaataca tgtctgatct cttgtttttt attgggcaac agacctctta
    37621 gaatgtataa agataaattt tacaaacgct ttcggttcag ttataataat aaatgataac
    37681 ttgtatatat aagttgtggt aggtaataaa tcagttgaat ggaggtaaat atccatgaca
    37741 tttaaagaca aagtcattta ccaaatctat cccaaatctt acaaagacag taatggtgat
    37801 ggaattggag atttaaaagg aatcaaagaa aaactcccgt atctgaatga tctaggcatc
    37861 gacatgattt ggctaaaccc tatttatcca agccctcaaa aagacaacgg ttatgatatc
    37921 tctgattaca cagccatcga tcctatcttt ggtacgatgg aggaattcga acagctaata
    37981 gccgaagcaa agaaataccg gatagaaatc atgctcgata tggtgctgaa tcacgtttcg
    38041 acagaacatg aatggttcaa aaaagcacta gcaggggacc agcattatca ggacttcttc
    38101 attttaagag aagagccaac ggattgggta tcaaaatttg gtggaagtgc ttggtcgcca
    38161 tttggagata cggggaaata ttatttgcac ttatatgatc ggacacaagc tgacttgaac
    38221 tggcggaacc aagcagtaag agaggaacta ttcaaagttg ttcgtttttg gatggaaaaa
    38281 ggggtaaaag gattccgttt cgatgttatc aatgttatcg gtaaagacga acaattgaaa
    38341 aataataaag aaaatgatgg caaacctgaa tatacggaca aaccaatcac ccatacgtat
    38401 ctaaaagaat tgaaccaagc aacgtttggg acggattcca ctatcatcac agtcggtgaa
    38461 atgagctcta cgacgatcga aaattgtatc ttgtatacag aacctagtag agaagaatta
    38521 tcaatggtct ttaatttcca tcatttgaaa gtcgattatg aaaatgggaa taaatggtct
    38581 actcctccat ttgattttgc agaattaaag cgactatttc atacatgggg agaaaagatg
    38641 agtgagggta acggctggaa tgctctattt tttaataatc atgatcagcc acgtgcgctc
    38701 aatcgatttg tagctatcga tcagtatcga aaacaaggag cagagatgct agcaaccatg
    38761 atccatttga accgtgggac gccctatatt tatatgggag aagaaatcgg catgatcgac
    38821 ccagactatt catcgatttc cgactatatt gacgtagaaa gtttgaatgc ttataagtta
    38881 ctccttgaac aaggattcac agaaaaagaa gcgtttcgtc ggatcaaagc aaaatctcgc
    38941 gataactctc gaacacccat gcaatggtca gacacagaac aagcaggatt tactacaggg
    39001 aaaccttggt taaaagttgg aggcaagcta gaagagatta atgtagaaaa agaactatct
    39061 tctgaagatt ctattttgtc ctattacaag aaattgattc ggctgagaaa aacatatcca
    39121 atcgttgcac aaggagatta tcatgcttat gaagcaaatc atccggaagt ttatggcttt
    39181 cttcgccaat ttgaaggaca gcagctgctt gtattaacaa atttctatga taaagataca
    39241 aggatcgcca tcccagaagg attcacagaa gccaatattc ttatcgataa ttattccgat
    39301 actgttcttc atcaaagtct ggagctaaaa ccataccagg caattgcttt gctgaaaaat
    39361 taaaacaaaa acacaaaacg tcgttcctac gagctattct cgtaagatcg acgttttgtg
    39421 ttttatttaa aataatcttc ttcagaaaat gaagagtttt catactctcc tttatcgcca
    39481 taaaatttat tgtagcgttg tttgaattta cggaaaataa aagtaacgag taatttgact
    39541 aacgtataga taggaatacc aaaaataacg cccacaattc ccattagatc acccatgaca
    39601 agtaaaacga ttaagatcgt aatcggatgg atctgtaaac gatcacccat tactcgagga
    39661 atcaccaagt caccgtggag aagttgtacg gcaaaccaga caatgacaaa tttgacagcc
    39721 ataaaagtag agtcttggaa tgcaatgatc aaacctggaa agaaggcgat aaacggccca
    39781 atatatggaa tgatacataa caacccagca gaaatagcta aaacactagc aaattctaat
    39841 ccgatcagta agaaacaaac ccagtagact gctccaagga taaatgaagc aatgatttgc
    39901 ccctttagaa atgaacccaa ttgttgatta gcaatctttg tcaaattttt aaaatctgta
    39961 cgaaatgctg gtgggacaat cgctaaaact gactgataaa atttttgagg atctctcaaa
    40021 aggaaaaaag cgacaattgg accagtaaat aaagtaataa aaatagctgt aacagttgaa
    40081 aaaatgttgc tgatccgttg tgcgccactt tcccaataat ttccaataaa tccagctata
    40141 tcagacgtca cgtcgtcaat agaagcgaaa aattgattaa atgaatcggc aaaaggtgtt
    40201 ttctccaaaa attgtcggag actctcttga aaatcttgaa acaaatctgg caaactactg
    40261 atcaatgtct ttgcctgttc ttcaagaaaa ggaataagcc atatgcttcc aagccccaat
    40321 aaaaataaaa taatcacata aacgataatg actgacaagt tcctcgaaag gtgcttgctc
    40381 aaacgtttga tgactggttc caaaagataa tacaagatca gtgcaaacaa taatgggggc
    40441 aagatagtag cgataatgat tccgacaggc ttgaatataa acgagatctg atggaaaaaa
    40501 taaatgatca gcgcaagtaa gataactatt cctaaaacat agtaagaggt ttttcctcct
    40561 aaaaagcgga tcaaacgatt cgttgtatct gtttcttttt tcactctttt tcctccttta
    40621 tctataactt cattatagac aaaagcgggt ataaaaggaa aatgatagag gttgattgca
    40681 aaaatatcgt caatcattca tataaacttt ctcatcaatt aaaataagaa aacgcttgac
    40741 agttctttta accatatgat aaattaaatc ctgttgctaa aacgtaacta ttacggtttg
    40801 cgaaaagcga atcggaacat tcaaatgaaa gaagatgaga agaggagtgt cataaatgaa
    40861 acgattgata ggtatattgg ccatgctggt tttagcaggt atgttaactg cttgcggggc
    40921 aagtgggaaa gccgaggaca gtaaagaaaa attgagcgtg atgacgacct tttatcccat
    40981 gtatgatttt acaaaagcaa tcgtcgggga tgaaggagaa gtagagttat tgattccagc
    41041 agggactgat tcccacgatt atgaaccttc tgctaaagac atggcaaaga tccaagatac
    41101 agatatcttt gtttataatg atgaaaacat ggaaacatgg gtccccgcaa tccaaaaaac
    41161 attacaagaa ggcaatgtcc atacgataaa agcgacagaa ggtatgcttt tacttccggg
    41221 aagtgaagaa ggacatgatc atgaccatga acacggggaa gaaggccata cacatgagct
    41281 agacccacat gtatggctag ctccaagttt agcaatcaag caggtagcaa acatacgtga
    41341 tcagctgatt gaagcttacc cagaaaaaca ggaagtatgg acaaaaaatg cagcagccta
    41401 taccgagaaa cttcaagcac tccatcagct ttatcaagaa acctttaagc aagcaaaaca
    41461 aagatctttt gtcacgcaac atgctgcatt caactatcta gcgttagaat atggattgaa
    41521 tcaagtatcg attgctggtc tttcttctag tgaagaaccg tctgcggcga gaattgctga
    41581 actgaaacac tttgttaaag aacatggaat caactatatt tattttgaag aaaacgccaa
    41641 agatagtatt gccagaacgt tagcaaacga agcaggtgta tctttagaag tattgaatcc
    41701 tttggaagga ttgacgaatg aacaaataga aaatggagaa aactatcttt ctatcatgga
    41761 agcaaacctc gaagcgttga aaaaaacgac agagacagaa aacccgctag aagatacttt
    41821 gacccccaaa aaagaaaaga gcgtctacaa cggttatttt gaagacgagg atgtacaaga
    41881 tcgctctctt tcagattggg caggaacttg gcaaacagta gatacgtatg tagaagatgg
    41941 gacttttgat cctgtttttg aatataaaga aaaattgaat caggataaga cagcacaaga
    42001 atataaagaa tattatacga agggctatca aacagatatt gcttcaatca agatcagtga
    42061 gaaagagatg gcatttacgt ttaagaatgg aacaacgaaa cgttcaaatt atcgttatgt
    42121 agggaaagaa atcttgacct acgaggcagg aaaccgtggc gtaaggtatc tattcgaagc
    42181 agaagataag gaaagtggcg cttttagata tattcaattc agtgatcaca cgattgcacc
    42241 ggctgactcc gaacattttc atttatatgc aggaaatgaa agtcaagaag tattgctgaa
    42301 agaaatggag aattggccaa cattttatcc agatacaatg gatggacgtg aaattgcaca
    42361 ggaaatgctt ttgcactgat aggcaaaaaa gaaccgaagg gtttggatcg gctggtcatt
    42421 tagtcggtcc aaactattcg gttcttttta tgaaatcaat ttctttaatc cacggataga
    42481 ggctgggatg gtctcgccgt ttgccaacgt gacttctctg gtttttttat taatcgaccg
    42541 cacattttgt gtattgataa cataggattt atgacaacgg ataaaattcc gatgcatttt
    42601 ctcgatttct ttgatcttct catagaattg taattgggca tgagtcaaat ggacttccag
    42661 tttatgtggc gctcctagcg aagtagaaaa atattggatg tctttgatcg gtaaaaattt
    42721 gatctcatca ttaaactcta ttttgaagat atctttttgg atttgggaca tttgaaaatc
    42781 ttcgaaaatt ttgctcagga tatgctcgac attttctttt aaatcataaa gatcttcttt
    42841 gacgatataa tcagtcggtt cgatgttgct ttttaagatt ttcatcgaca tttccgtatg
    42901 ggaagtcaca tagattattt ttcctaaagg atctaattca cggatcaatt taccgatcgc
    42961 tacaccatcc atttcactgt cttctagttc gatatctaaa aagtaaatac caaaagaaga
    43021 agttctgatc ttggctgcat tgagaagttc ttccggatca gaggtagaaa tatggacata
    43081 actgtctaag ttttcaatca tgattctatt tttgatcacc gttgataaaa cttctaattg
    43141 ttttggatcg tcttcacaaa tataaatggg aatcatatca ttactccttt attttatttg
    43201 tatataaatc gtttgagaaa aacgctggtt ttcaattgat gtttcaagga aaagataagg
    43261 attggtcttt gtcaattcat ccaagataaa caagccaagg ccttcgtttt ttggatttgt
    43321 ttttgttgag aacccttttt gtttcaactg gtttaacggt aatgtatttg ttgttgtatt
    43381 gatcacacga atcatcacgg aatgattctt cttgagtatg gtcaattcga tttttttctt
    43441 ctttgcagca ctagctcctt caatcgcatt gtccaagata ataccaagca tacgtacaag
    43501 gtttaccgta tgtttcgtat ccagttcgat tggctcagga aaatgaagct ggacgatcaa
    43561 ccctttttcc tgtgccatca tgagttttaa tgacagtaaa ctacggatct caggaacttt
    43621 catattatcc aacatactta gattggccgg aaaaaggttc atcatctggc gtgtaggtaa
    43681 tatcgtttga tcataataag accgtaatcc ttctaagtcg ccttctgaaa tatagctgtg
    43741 aagagaaaaa agcagatttt ggtaatcatg tttgaattct ctcaagtctt gatagttttt
    43801 ttctagatct ttgatataat cctgttgcat cctgacttgt tgctctaata actgatcagc
    43861 taatttctta ttagagattt tccaataata aaccaagatg atcaggccaa cacacagata
    43921 tagaatgaaa aaactcgtat tcaaagctaa gacatcaggt gtttcaccag aaaaacgggt
    43981 ataaaaaata atgatatagt atgtaaataa tatcaatgtc ccgatcgtac cgatcatacg
    44041 gcggtccaca gtgtgaaacc aagtctctaa cgattttttt aaacaaaaag ctaataaagc
    44101 agataaaaaa gcggataaga caatgtgaaa atactgcaat gaatctcctg gttcaataac
    44161 cgaagatttc aaaacaaaaa aatcgccgat gcttgttaag tgatctccta aaagcgacgt
    44221 caataaccca aaaggaagcg cgtaaaccaa ttgttgacgc gaagtcgaaa agaagaaaaa
    44281 agtaagcatc agcattccta tagcaattag agcagtaaaa atccctaaaa tcgaatagac
    44341 ccatccaatc aaaatacaag aaatcagaat gactcccgca aacagatatt tgtatcggat
    44401 gtgatggtca atcaataaga tacaaattgt gtaaatcaaa tattgcaacg ctatggacca
    44461 taaaaacata aagtacagct cccattgatt tttaccaaat tatagcacaa ttggcgtatt
    44521 atttttttaa tttttcaggg attttgaatt cagaactcat accaaagcag cagccagata
    44581 caaaaaagtc agataagtta gttaattgtt taatgattgt ttttttcatg aaagattcct
    44641 ccaaaattca tcaagtagtt tgtaatagga agcaacgtag ctatttctaa aacaatccca
    44701 agtagcaaat aggtagaaaa gtaagaagct gagaaaaata acgtaatgag agaaaaaatt
    44761 agaaacatgc tgatcgcctt ctttaataat gggggacgtt tctcgggttc aatgggattg
    44821 attgctgtac ctcttgatcc atagcgaagc agtaacaaaa agcagctgat taacaaaaag
    44881 accatcattg ggaaggagat agtcaattgc agatgtttca tcaccaaggg aacgccccat
    44941 aaataaagta gtgtccacag cagacaaacg aattcagagt cggaatgcaa tccataagca
    45001 tatctgcgga tgcagatata agaaagaaag gtgattcctg tttccgccca tgagcctgtc
    45061 accagagaaa agactagaac gaccgctagt tttccaagat tattcaataa aacttctaag
    45121 acaaatttta cttggacata caccatatct tcttccgatt tgtctccgct gaataaggct
    45181 tctaataatt tgttcacaac tttatctttc atctcatacg tacctccacc acaaatttta
    45241 tgctaaaaaa aataaaaaac gtcttttgtt tcataaaaag tggttttgac atcaaaaccg
    45301 tcatgatctc ctaaaaaaat cttcgttttc caagaacctt accaaaaaaa gtgacagttt
    45361 tgatacgaaa agtacttttt atgacaagtt tgtgcttttt cgagtgattt atgttaaaaa
    45421 attactgacc ttataaaagg tgatggaggg attcttatgg aaaatgaaca attgtttgaa
    45481 gtcggcgaaa catatgcatt taaatctgat ttatttgaat caccaataaa aggaaaaata
    45541 gaaaaaatct atgaaaatag tgtgatgata cgtgtcatga aatgcgcagt agaagacaat
    45601 gataccgctc ataatctgca ctggcagtta gttgtacgca aatcaagtac aatagaagaa
    45661 taaaaacaga taaaatgttg agagcataaa gaggttgtga gtctcccgtt tagctctgag
    45721 ttacaaggaa taatgttaaa aaacagcttt tcatgtttta tgaatattgc cttgtgaccg
    45781 aggtgttggc aggagaatac tgtttatttg aaaaaagggc tgcgacaaga cttttgtcac
    45841 agcctttatt ttcatgaata ggagttactt ttggctactt ttagagaagt agcttttaag
    45901 gagcagataa agtcaaggct tttatttcta taaatgaagt agtaaaatga agaacagatt
    45961 ttattacagg aaggatgccg ataattgtga tcattgttgc aggaacgatc ggtgcaggga
    46021 aaagcacact aactgaaatg cttgcccaag atttagaaac aaaacctttt tatgagaacg
    46081 tggaagataa tgaagtattg ccgctatttt attctaatcc agaaaagtat acttttttat
    46141 tacagatttt ctttttgaac aaacgctttt tggcaatcaa agatgctttc agccatgatg
    46201 acaacgtact agaccgctcc atctacgaag atagtatgct gtttcatttg aatgcagatt
    46261 tagggcgtgt ttctgaagta gaagtaaagc agtatgaagg tcttttagaa acgatgctga
    46321 aggagttaga agaaatttcg ccacaaaaga aaccagatct actggtttat attcgtgtat
    46381 cctttgaaac tatgttagcg agaatcaaaa aaagaggccg ggaatatgaa cagctagaac
    46441 aagatcctga actctattcc tactataaag aactcaatcg acgatacgaa gagtggtatg
    46501 aacagtttga tatatgtccc aaaatagtga tcgatgggga caaatatgat ttcgtagccg
    46561 atccggcatg tggagaacaa atcgtacaag aaatcaagat gcgggcaaag aaaatgacag
    46621 aagaggcaga tgcccagtcg atccgctaca ctacaaataa cccgaaagca aagggaatct
    46681 ttacaactaa ataatataaa aactaagcaa attgctcact cgcagatatt tctctgtgag
    46741 cagcatcttg cttagttttt ttgattcatt gagatcaaat agtgaaccga ttcgtatgat
    46801 aaaattgcca taaatgaaat gtctgagtga gggccatgat caaaaataaa atggaaacga
    46861 tcaaaatcga atgggcgcca aacagatgat gacagaaaac aaggacaata gctcctgcga
    46921 taaaggcaag aacgacactt agatagtgga aaaatcgatc aaaatctgct ttttctttag
    46981 aaatacaata atcatataag ttcgttgcta ccccttttaa atttccagtt gtaaataaat
    47041 tagtgtaggc acgcccgttg attttatcaa aagctaccca ctggatcgat gcagtaaaag
    47101 caatcaaaat cgttactaat gcgggatgct catggacggg tgtcaaacta acaaagaaaa
    47161 aaatcactgc ttcataatat agaacaaaca agcgccagaa atgtttttct ttttttctaa
    47221 aataatcaat tagatacttt gttagaagaa tccctaagaa aaagaaaagg gtagacaata
    47281 cttttttacc aacacttagc cattctccgt caaatgcttg gatgatcgat agaatgatat
    47341 tgccagtttg agcagaggca aaagcaccat attggatata agtataactg tccatggctc
    47401 ctccgataaa tgtcagcaaa agtcctattg tacgcccctc gtgaaaggaa gtctgcattt
    47461 ttttcatcac cttttatgaa tatttttgtc ttccttatct tagcataaac gattgaaaaa
    47521 aaaggaaaaa ttttcagaaa actaaaatca tatcgcttcc cattttcatt tttagaaagg
    47581 tctgttagta taaagaaaaa atagacaacg aaactttaaa taaccaactt gaaataaaca
    47641 aattcaaaga agaaagatgg gaaggaaatc aatcagttga atgaaaaaga aattctccga
    47701 ttacaaaaag aattgaaacg ctgggagaac aagtataaaa agcttcaaca agtctttcgg
    47761 ctacaagaag aaatcattgc tacctatgaa gcggcttatg gcgaagcacc cggacttatt
    47821 gaggaagaag tacaagtaaa agaaagtgaa ggaaacagct ctttctttaa aatgatggag
    47881 aaacgttcct ataatcgctt caatcaagaa caaaaagcag ctatcacata tgatatgaag
    47941 aaacatcttc gaatcatagc aggagctggg agcggcaaaa cgcaaacaat ctgtgcaaaa
    48001 gctgtttatc tgatgacgca aaaacaagta gacgaagaac gcatactaat gatcactttt
    48061 acaaggaacg ctgcaaatga actaaaaaaa cgagtagata atttcagcca gagaaaaacc
    48121 gctgtccata tcggaacatt ccatagtatc ttttttagga tatacaatga aatttgtcga
    48181 aaatttcctg aagtagcaat gcaaggaata caaggagact tttcaaagga tactgcacaa
    48241 aaagtgaatg ctgttttgca acagctgata cgtaaatata atctttatat atttgatcaa
    48301 tatggagaaa aaacgattgc ttctcggtta gactattggc agaatatgaa cctttcagta
    48361 gaagaaatgg ttcagttagt taaagaaaaa tatgattcca ttgataagaa tgcacgacag
    48421 ccgatatcag aacgactgta tggattgctc acggaactcc aagaacaaaa aagaagccag
    48481 caattgctag agttcaatga tgtactccaa aatctgaaaa gcgctttgga gaatgaggag
    48541 atccagcatt atatcggcca aaaatatgat tatctattca ttgatgaatt tcaagatact
    48601 aatccacttc aatgggaaat cgtgaaacgg atgacaaagg aaaacaggat caagttgatt
    48661 gttgttggag atgatgatca gagtatctat ggattcagag gatcagagcc agcatacatc
    48721 aagaactttg aaaaagaata tcctaccaaa actcttttct tattaactaa ttatcgttct
    48781 cgggcagcta ttgtccaagg agcaaataga ttgatcagct ataataaaaa tgatcggata
    48841 ccaaaggcga tgattccagc acaaaaagaa gcaggtgtta tggaagccta tttgttttct
    48901 gatactaaag cagaaagtca gtggctaatc aaacaaattc agacatttat tcaaaaaaat
    48961 gggaaatata aggaatcaat catattatac cgatcagctt cacaaacgca gcagcttgtc
    49021 caatctctgc tgaaaacgaa tattcctttt gtactggaag cagatagtcc atatgaaggt
    49081 atctttggta tcaagtcttt ccaacatttc tatcaaaaaa ttgttcattg gcaaacagca
    49141 ctgaatctgc aaaagaaaaa tcaggcctac cagcaattgc tccggcagct gatggcagac
    49201 tgctacctga aaaaaagtga atgcgatcaa tacttttctc ctaaatatca aaatatagcc
    49261 gttgcagatt atattttgtc gataagcccc aatttaaaat cgaaatctgc agaaatccga
    49321 gagtttgagg aagcgttgcg taaaacagac cagcatcaag aaatctattc gcttgttcaa
    49381 agctatcttc atctgccacg tatagctaag gaaatcgacc agagtgatca agaatggata
    49441 cgagaagaag taaagcagca tgctactttc agaagactcc aagccttatc gcaagaaacc
    49501 caagcgacag ctaaagaatt aaaaacccgc ttgattgctt acagacaagg aaaacttgat
    49561 gcactatgta tccagagcat tcacaaaagt aaaggtctta gttaccgaaa tgtctttttg
    49621 attggttgta acgaaggaag tttgccttat aacggagcga cagaaaagaa agtaatcgac
    49681 tttaatgaaa taaaagcaga accagtaacg acgatagaag aagaacgaag actattttat
    49741 gttgcgatga ctagagcaag aaatcgtctg tatctatgtg tacctcaaat gaaaaattca
    49801 agaaaattga aagtatcgag atttatcaaa gaaaccggga gtcgtgtgaa aaaaggaaag
    49861 tgatagaaga gagggtgtga cagaagtggt cagtttcaag aaagaagaag gaatgtacga
    49921 aaattgcttc tcaaattttt gtgaaatttc agcttatttt cgaagaagct atttctggaa
    49981 cacagtttat tcggaaaagg gaggtgtgac aagaattttg tcacacctcc cttatttatt
    50041 ttgaaaatga gaatactatt atcaaaatag agaatatata gaaaaattct cattattcaa
    50101 acgtaaataa tcagttattt tgattttttt tatattttat tagctaataa ttggtatttt
    50161 aaaagaaatt actgtagaat tggattataa ttaaaaagga gtgagaaaat gataaaagta
    50221 tatacttcgc ctagctgtac ttcctgtaga aaagcaagag catggttgaa agcgaatcaa
    50281 cttgaatttg aagagaagaa tatttttgcc gaaccgttaa cagaaagtga gatcaaaaag
    50341 atcttggcag cgactgaagg aggagttcaa gatattattt ccactcggtc gaaaatttac
    50401 gaaaagctgg gcatagattt taacgaatta actttaaagc aaatgatcgt cttattcaaa
    50461 gaatatcctt cattattgag acgacctatt ttgattgatg aaaaaagaat actaatcgga
    50521 tttaatgaag atgagatccg gtcatttgtc cctcgtgaaa ttcgatgtgt tgccagaaat
    50581 ctgatctatt tacaaaacaa taacatctta aattcatagg gagggagcct tcgtggaagt
    50641 gaaagtctat ggatcagcgc actgtgtaac aagtctgaag gcgaaacaat ggttagaaca
    50701 ccatcaattg ccttatcaat ttgttgactt agaagaacgc gatttaagta cagaagaagc
    50761 agaagaatta tgcagttttg aagaagtgca agcagaacag ctatttgcga cttggtctga
    50821 ggcttttcac aacattgcga ttgacctttc ctgtgtagga aaaaaacaac tgattttttt
    50881 atgcacacaa cataccaatc tcctcagacg tcctttgatt attatcgatg aagttctatt
    50941 tattggatac aatgagcagt tgatggaaca gcttatctta aataaataga ctttaactgt
    51001 tttaatcaag tcactgagca tttcatacag ttgtaacagt cgaacactta gcatcaagcg
    51061 tgttatgtgt tctttttttg actttatttt tctactatag agacatgctc aatttatgtg
    51121 gtcaaaattc aaatctaggt ggggatatag agttaaaaat atattgacat gtgtaaattt
    51181 acatgatata ttcatttctg ttgttttaag tagcaaagca ataaaatagt attttaaaaa
    51241 acatataaaa tagttgttga catgttagaa atgacatgat aagataactg agttgttaaa
    51301 aaagaaccac ttgtgaagct tgattctatc gaaaaaaact tcaaaaaagt tcttgacaaa
    51361 taacaaatga taagttatga taaatgagtt gctgtaagat ttcgaaaaac gaaatcaaaa
    51421 aaacttttaa aaaagagttg acaattactt gtctctctga tatgatataa aagttgctac
    51481 ggcagccaaa aacgaatcgg ggaacactcc tgatgaagta gacctttgaa aactgaacaa
    51541 agtaagacaa accaaatgtg tagggcgtct tgattcaatt caagacaaca aaca
//
LOCUS       DAZUJR010000008        49299 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.008, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000008 DAZUJR010000000
VERSION     DAZUJR010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 49299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49299
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.008"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1087
                     /locus_tag="ACG804_000452"
     CDS             <1..1087
                     /locus_tag="ACG804_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4831410.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
     gene            complement(1294..2436)
                     /locus_tag="ACG804_000453"
     CDS             complement(1294..2436)
                     /locus_tag="ACG804_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4831411.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGIYLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(2441..2626)
                     /locus_tag="ACG804_000454"
     CDS             complement(2441..2626)
                     /locus_tag="ACG804_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HFS4831412.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
     gene            complement(2980..3225)
                     /locus_tag="ACG804_000455"
     CDS             complement(2980..3225)
                     /locus_tag="ACG804_000455"
                     /inference="COORDINATES: protein motif:HMM:NF024059.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4831413.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(3219..3620)
                     /locus_tag="ACG804_000456"
     CDS             complement(3219..3620)
                     /locus_tag="ACG804_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFS4831414.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            complement(3807..5615)
                     /gene="uidA"
                     /locus_tag="ACG804_000457"
     CDS             complement(3807..5615)
                     /gene="uidA"
                     /locus_tag="ACG804_000457"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HFS4831415.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KFITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDVCKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWMERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAYYLQKRWSSIPNFSYKK"
     gene            complement(5638..7404)
                     /locus_tag="ACG804_000458"
     CDS             complement(5638..7404)
                     /locus_tag="ACG804_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 3 N-terminal
                     domain-containing protein"
                     /protein_id="HFS4831416.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IITDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            complement(7417..8211)
                     /locus_tag="ACG804_000459"
     CDS             complement(7417..8211)
                     /locus_tag="ACG804_000459"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFS4831417.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGDYVDIEQKYIDTFWKNLTNK"
     gene            complement(8221..9597)
                     /locus_tag="ACG804_000460"
     CDS             complement(8221..9597)
                     /locus_tag="ACG804_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4831418.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLVIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQYKVSLLKSLKGLVKNRALLSIIGAAIFLLLAQLLIMSMNNYVFPDYYNDAQGIV
                     LMNFINPILVLIVVSPLTLFLSKKYGKKELASVGMFFSAIVYLILFLIKASNMYVFLI
                     LSSVGYMGLGVFNTVIWANITDVIDDQEVKSDQREDGTVYAVYSFARKIGQALAGGVG
                     GWTLSIIGYDSLANVQTGDVLEKLYNASTLIPSICFLIVGLILFFLYPLSKDKVLENC
                     ELLKQKHK"
     gene            complement(9717..10364)
                     /locus_tag="ACG804_000461"
     CDS             complement(9717..10364)
                     /locus_tag="ACG804_000461"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HFS4831419.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSIENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            complement(10448..11875)
                     /gene="uxaC"
                     /locus_tag="ACG804_000462"
     CDS             complement(10448..11875)
                     /gene="uxaC"
                     /locus_tag="ACG804_000462"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HFS4831420.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLWYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQTAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            complement(11949..13028)
                     /gene="uxuA"
                     /locus_tag="ACG804_000463"
     CDS             complement(11949..13028)
                     /gene="uxuA"
                     /locus_tag="ACG804_000463"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFS4831421.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIREVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPACEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(13031..14662)
                     /locus_tag="ACG804_000464"
     CDS             complement(13031..14662)
                     /locus_tag="ACG804_000464"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HFS4831422.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSKIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            14966..15637
                     /locus_tag="ACG804_000465"
     CDS             14966..15637
                     /locus_tag="ACG804_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFS4831423.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQQGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKMNNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKNI"
     gene            complement(15797..15988)
                     /locus_tag="ACG804_000466"
                     /pseudo
     CDS             complement(15797..15988)
                     /locus_tag="ACG804_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
     gene            complement(16356..16697)
                     /locus_tag="ACG804_000467"
     CDS             complement(16356..16697)
                     /locus_tag="ACG804_000467"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831424.1"
                     /translation="MSIDDCLEEQIRLFLKFLKVKVQNNYFTCYSYAHPVLNSLPFNS
                     LVQGLITNIVLLVCTPNEIFVKKIGSGISSVRLKEKEYTQKIIHIPKPEIKRFEIKDY
                     SALGLFSIGYW"
     gene            complement(16794..17246)
                     /locus_tag="ACG804_000468"
     CDS             complement(16794..17246)
                     /locus_tag="ACG804_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831425.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFLPDELVIVNEKITSKNEVFNYSLTRINYKEITKFSLEKVPFWG
                     EFCLKIKCNWKRMYFYIDGDDALTFGKTTFSSFNFQFLLKNNFYGLLK"
     gene            complement(17253..17801)
                     /locus_tag="ACG804_000469"
     CDS             complement(17253..17801)
                     /locus_tag="ACG804_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HFS4831426.1"
                     /translation="MKRIIKIFGVLGVFLLGLSTFVSTGTSVYATEKVNTVDLEIKNK
                     LVDELTFYFDTVGFLDEHGVYHIKDFGAIRERISQDNEQGRAARVFYEHIIVPRMEKV
                     DWKRYAGCVAINSLPGGGVAWAIGTQGDFIEALKAFNFEKAADLLLKIAEKQLGKAAA
                     KELAKVNIVAGIAAAAASCALE"
     gene            complement(17846..18178)
                     /locus_tag="ACG804_000470"
     CDS             complement(17846..18178)
                     /locus_tag="ACG804_000470"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831427.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            complement(18192..18449)
                     /locus_tag="ACG804_000471"
     CDS             complement(18192..18449)
                     /locus_tag="ACG804_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831428.1"
                     /translation="MKKLIGYSVMCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQ
                     KGYPYGPTNLKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            complement(18644..19186)
                     /locus_tag="ACG804_000472"
     CDS             complement(18644..19186)
                     /locus_tag="ACG804_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF0163 family protein"
                     /protein_id="HFS4831429.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFVLLQLK
                     VDQEAQKIDAIKIYYVRSAY"
     gene            complement(19207..20298)
                     /locus_tag="ACG804_000473"
     CDS             complement(19207..20298)
                     /locus_tag="ACG804_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFS4831430.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            complement(20306..22516)
                     /locus_tag="ACG804_000474"
     CDS             complement(20306..22516)
                     /locus_tag="ACG804_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HFS4831431.1"
                     /translation="MAYIKHKEKKWCVLFFLTIGFGLLFVGGLVYAAEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYILLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPVFDYMLMNTLKSFLGLMFQKSFYSVIILVAFLIY
                     NIVDDLIPMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGRQVVNPFELGGRSNQALPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQLSKQQGNNQRKPLLNKGIAFVGQSIPLPSGKVPVPQLTAAGSLS
                     QQIRQVKNQAKNGSYPAMQQLLNQYSVPNSSVATLSGNRSVQQPGQRSSESKPSISAP
                     KSLQPAFSSLDKPTEQSEKIEKDPKTLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            complement(22532..25060)
                     /locus_tag="ACG804_000475"
     CDS             complement(22532..25060)
                     /locus_tag="ACG804_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFS4831432.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVINLIWLDLAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEHKGLLQLEDELGSSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATVIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
     gene            complement(25112..25522)
                     /locus_tag="ACG804_000476"
     CDS             complement(25112..25522)
                     /locus_tag="ACG804_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TcpE family conjugal transfer membrane protein"
                     /protein_id="HFS4831433.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFYIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYMI
                     RMMNGDCVYYNWDKVSNNALEELLFVNKYVYLED"
     gene            complement(25535..25753)
                     /locus_tag="ACG804_000477"
     CDS             complement(25535..25753)
                     /locus_tag="ACG804_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TcpD family membrane protein"
                     /protein_id="HFS4831434.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            complement(25750..26742)
                     /locus_tag="ACG804_000478"
     CDS             complement(25750..26742)
                     /locus_tag="ACG804_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFS4831435.1"
                     /translation="MKKRQLRRKEKVYTEKVPKQKKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSRSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQETLKKEFYAQNFIQEPGSVSGVRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMNPESKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKPFIVKATVVFRDGDTSLLQKEQMTIVITKKTNQYYVEKLTHNWLDRKGEERK"
     gene            complement(26821..27732)
                     /locus_tag="ACG804_000479"
     CDS             complement(26821..27732)
                     /locus_tag="ACG804_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFS4831436.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVPAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            complement(27751..28095)
                     /locus_tag="ACG804_000480"
     CDS             complement(27751..28095)
                     /locus_tag="ACG804_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831437.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            complement(28115..28393)
                     /locus_tag="ACG804_000481"
     CDS             complement(28115..28393)
                     /locus_tag="ACG804_000481"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831438.1"
                     /translation="MSVEHFCDCYIALLRSQQLLTVERYGAEFGYVLQAERHRATRCY
                     EKEDQVIDGYEELCIRNNRYLQQRLYEQLMMDFSNLYRGYECSMIQER"
     gene            complement(28752..29252)
                     /locus_tag="ACG804_000482"
     CDS             complement(28752..29252)
                     /locus_tag="ACG804_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831439.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            complement(29253..29798)
                     /locus_tag="ACG804_000483"
     CDS             complement(29253..29798)
                     /locus_tag="ACG804_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831440.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            complement(29795..31051)
                     /locus_tag="ACG804_000484"
     CDS             complement(29795..31051)
                     /locus_tag="ACG804_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFS4831441.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQTD
                     WRTWLYSIWKNQGKLEAGYTRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKRFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISELEAL
                     TKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIDNAELNDEQQNYLEWMGTSGGKIA"
     gene            complement(31412..31723)
                     /locus_tag="ACG804_000485"
     CDS             complement(31412..31723)
                     /locus_tag="ACG804_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831442.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRVDLEEDLTLSIYRVFSPEKYSEITKLDHLI
                     L"
     gene            complement(31746..33221)
                     /locus_tag="ACG804_000486"
     CDS             complement(31746..33221)
                     /locus_tag="ACG804_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HFS4831443.1"
                     /translation="MKAHFFKYRGRRIRYFNRYLWFCYYGFFLFPFLILLGWFSWKVF
                     YPRLSTFSNWQMYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLVRML
                     IDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGHLLS
                     EVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPNMLI
                     AGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEEMII
                     CLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDMEARN
                     RVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYLMTF
                     GEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYDFTV
                     KEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            complement(33670..34122)
                     /locus_tag="ACG804_000487"
     CDS             complement(33670..34122)
                     /locus_tag="ACG804_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831444.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            complement(34124..34489)
                     /locus_tag="ACG804_000488"
     CDS             complement(34124..34489)
                     /locus_tag="ACG804_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831445.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            complement(34588..38871)
                     /locus_tag="ACG804_000489"
     CDS             complement(34588..38871)
                     /locus_tag="ACG804_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HFS4831446.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTAIQPTMEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPGT
                     SQPVEETASITTPASETSTLEGEKAAEATPSVQPESSEKQAEEKKRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKPNKESTASIENQKKKEQNIPKTGTPTLLVTVP
                     TNRSVRVRRATNAAVLGGRKIDWGENIGVTSSPNNLNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALKNYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLINNFGEKATFNNQTHTVKIGETLKVKNKNDFLKYV
                     KDIQKPKGVNVSIHGNEVWITVTKEAPDKAKIQLNKIKVQGAPLAYRRPGAQTIGVLH
                     PTEPNASVINLQILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KKINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEITLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVN
                     FTLYNGKNQAIGEYTTDQNGEILVKGLVADDYYFLENAPLESFQPNTDKQAFTVAFKQ
                     NAPDDGETLVVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQDGKEITSTLAFIADKVNGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAAHADINDEAQSVKVNNPTVHTTAVFEDGLTVADPTGLFTLNDTVEITE
                     ILPGKAYLVKGILMDKATGEPLLVHGNTVETSVGFIAKAENETVIVPFTFDLTGINGR
                     EIVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLVVGKTYTVNGVLMDKVTEKPVLVDGKEVTSTLTFVAETTDGTVNLDFILD
                     ARALRGKEVVVFEDLFREGVLLASHADITDNDQTIKISNPTITTKATNKNGGKEILAL
                     PNQTVLEWVKVDGLAIGQIYRLIVQGYLTPDGTPFEGTHAEKVFAADKEMMEFLFEFL
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVK
                     PEQRVKPATVVPMLPKTGEQTSSILMVLGLVVLVIALGITLYKVRKAKD"
     gene            complement(39018..39257)
                     /locus_tag="ACG804_000490"
     CDS             complement(39018..39257)
                     /locus_tag="ACG804_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831447.1"
                     /translation="MIDISLPEDLKPDPVTIGNSVMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVAKKAGIPIGKWTVDFHEAGSFFVL"
     gene            complement(39347..39589)
                     /locus_tag="ACG804_000491"
                     /pseudo
     CDS             complement(39347..39589)
                     /locus_tag="ACG804_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010708076.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(39702..39953)
                     /locus_tag="ACG804_000492"
     CDS             complement(39702..39953)
                     /locus_tag="ACG804_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831448.1"
                     /translation="MRKVLVFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTE
                     LKDKNNVEFFESDIGWDDHEEVYGKFILRKGNSYTNGEA"
     gene            complement(40949..41859)
                     /locus_tag="ACG804_000493"
                     /pseudo
     CDS             complement(40949..41859)
                     /locus_tag="ACG804_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353574.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(42055..43890)
                     /gene="lepA"
                     /locus_tag="ACG804_000494"
     CDS             complement(42055..43890)
                     /gene="lepA"
                     /locus_tag="ACG804_000494"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HFS4831449.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            44037..45257
                     /locus_tag="ACG804_000495"
     CDS             44037..45257
                     /locus_tag="ACG804_000495"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4831450.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            45277..45771
                     /locus_tag="ACG804_000496"
     CDS             45277..45771
                     /locus_tag="ACG804_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HFS4831451.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            45749..46435
                     /locus_tag="ACG804_000497"
     CDS             45749..46435
                     /locus_tag="ACG804_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831452.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(46586..49195)
                     /gene="clpB"
                     /locus_tag="ACG804_000498"
     CDS             complement(46586..49195)
                     /gene="clpB"
                     /locus_tag="ACG804_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HFS4831453.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
BASE COUNT        14949 a        10140 c         7253 g        16957 t
ORIGIN      
        1 agatatcaat gatgatggct caagaaaaaa agtggagaaa gttggcggag acacccgacc
       61 agaggccgaa gctgctttac gaaaagtttt atcagatatt gacgaaacag gacaatactt
      121 tttaggtacg gatactcgag taaaacaata ccttgatttt tggatggagg aatacgttaa
      181 actaaatcta aaatacaata cctatgaaaa ctaccgattt accatcaaaa atcatataaa
      241 cggttattta ggaaagaaaa aacttacgga tctctcccct gctcttttac aaaatttcat
      301 caatgctgaa tttaaaaagg gttactcgaa gaaaacaatg actattactc actctgtcct
      361 taagaatgcg ctgaatatgg cggtttatcc ttggggatta atcaagcaaa atcctatgct
      421 gtatgtaaaa ataccaaaat atgaagcacg accaacgact aaaaaagatc taaaaatcat
      481 ttctcttgag gactttgatc atatgctaga aattactcct gaaggacatc ctttctatat
      541 tcctttgaat attggatttt atacgggaat gcgcgttggc gaagtttgtg gtctgacgtg
      601 ggatgatgtc gatttttcaa atggaacaat tactgtagag aaacaaatgg taaagaatga
      661 cggcgcatgg gtatatggta cgccaaagac aagcagttcc aatcgaacga tttttattgg
      721 acaaaccttg ctagcaattc tgaaaaaaca taagaaacaa caattagaaa atcgaatgaa
      781 gtatggaaag ctctacattg attcaaatgc agtatgtacg aaggaagacg gtgagctagt
      841 tacgccaagt gtagtgaaat ggaatactag gaggatatcg aatgcactct ccctctcttt
      901 taacttccat tctctcagac atactcatgc tacacttctt ctcgaaaatg gcgcaaaaat
      961 gaaagaaatc tctgaacgat tgggccacag cagaatttca attacgatgg atacttactc
     1021 gcatgtaaca gataagatga gaaatgaaac ggtcgatatc atggaaaatc ttagaaagaa
     1081 ttcttgattt ttgccaccga aaaaaaccac cggtggcaaa tccatgtaaa catggtttat
     1141 tttttacact gttttcaaac aaacccttgc tatttcttcg gttcgtcctc gtccattttc
     1201 gataccgaca gctagcttat aacccaaggt atatcaacat aaaaaaataa aaataggcta
     1261 tgacagcagc gtgacagcaa aaaagatgga aagttaaata tcaaacctcg taatttcatt
     1321 tgcgagtgct tgatttgttt ctggatataa gtgtccatat ttgtccaaag tagttttaat
     1381 agaggcatga cctagacgct tagatattgc atagatattt ttattatgtt caattaaaaa
     1441 ggcaacatgc gagtgtctta atccatgcat atgaattggt tttactcctg caatttcagc
     1501 tagttttttt attctgctta aaatagttct tggagatggc ggtaatccat caaaagaaaa
     1561 aaccaattct atatttttcc caattgattg ttgagttttt ttccatgttt ttaaatcttc
     1621 aacggtttgt ctgtctaacg aaattatccg aatacttgat gtattttttg tttcagcaaa
     1681 ttcataatct tgtcttgtac ggatgtaaat tgacttattt acgctacatc tgccatttat
     1741 taagtcaaag tctttccatt gtaacgctaa gagctcctca ctccttacac ctgtaacaaa
     1801 aataaaacgc atcaaacgtt tataaaattc ttcataaaaa tccccgtgat aaacactatt
     1861 atatactttc ttaaattcat caactgtcca aaattctact tgaggacgct gagtttttat
     1921 tttacctata gtatctacag gattttcttc aataatttca agtacaattg cccttttaaa
     1981 aactactctc aacttattga atatctgttt aatataattt ggtgataatg gttgctcaat
     2041 gccctttttt acaacatgga ttttcgataa aaactgttga aattcctgta tatgaattgg
     2101 tcgaatcttt acaacctgca tttctccaaa aaaatccaat gcacgttgta aaatatgatc
     2161 tgttttcata tatgtttttt ctacagttcc caacttatac caaggaaaaa aatactctcg
     2221 ataaaaatca tgaaacgtta ttccttgcag ataaattcct tgtgaatcag aaaaactttg
     2281 ttttaactct tcgagtcccc ttctagcttc tccttgagtt ttgaagcctc ttctggtcac
     2341 ttgaattctt tttccaaagc gatcttgtcc taaagttgca gaaaaaaacc aagtgcctct
     2401 ttttctgtct ttataaacat tcgcaatttt cctcatttta ctattcctcc caagaaatat
     2461 ggagaacttc ttctaaaatt gaaataggaa ttctttttat ttttgaatta cgataaaaaa
     2521 agtatccttt ctcaactaaa agttctttac attccttgaa gattttatta gcatagtact
     2581 gagaaaaacc tagattaatc aaatcttttc gagtagctgt tttcattata gcaccttcct
     2641 tacttttttt catttatttc tatcagctgc ttttgtcaaa agcacatagg aatttcacct
     2701 ctccccaagt ttacggcgag ccttacggaa gtatcattat cccaacttta aatcatcgct
     2761 ttttattgac tataaaaatt attttagaat atttatcgct ccttctttac agcaagaaat
     2821 catggcgcaa ctaaaatatg ctccttaaag tgttaacgta ctgatagaat ctatttaatt
     2881 ttcaatgaac aataggtttt ctacctaaaa gaatctacta attccttaac tattagaaga
     2941 ttcttttaaa cagaaaaagt ggaaagggga tttttttaat tagttaattt taaattttaa
     3001 gatcgcttct attaatttaa tttctagctg acttatcata tattcatcta cataggtaac
     3061 gaattgacct acctcgttaa atccatttgt caaacataac ttagccatat aagaatgata
     3121 atgtttgagt atcatcttga tcgaaattgg atctccttct agagcagata agataatgga
     3181 tagtggaact aataggtact gccgcttttt agatttatct accataggtc ataccccatt
     3241 ttcaattgtt caactgcctt ctttcgttga taccagatac cacttgtgct catattgaga
     3301 attttaccga tttcagcatc attaaaacct gcaaaataat aaagtaggat aatctttctt
     3361 cttatctccg ataactgatc aattgctgct gataactttt gatctgaaat taatatttcc
     3421 attccaaata agaaatagac atcttgttca tcaaaatgag tttgggaata cctgccttca
     3481 tttgaatctg ccaatggttc ctcattatcc tttatgttag cgtttcgttt tcgaatagac
     3541 ttagcttcgt ttcgtaatac ttttttacag taggcatcaa attggtgttg tatagatatg
     3601 tcattgtaat gttgttgcat gataatatgc tcctttttcc ccctttccac taatacaaca
     3661 atcagaaagc cccttttttt cgaaaaaact agaaaaaaaa cataaaaata tttatcattc
     3721 tttaaacaga aaatctttct ataaaaaaca aaaaaaaacg attaggctag gctaatcgtt
     3781 ttttgaacat tcttaaaaaa tccaaattat tttttataac tgaaattggg tattgatgac
     3841 catcgtttct gtagatagta agcaatcatt ttaggttttc tatctctagt aaagattcct
     3901 ttcttatttc cttgcactct taaaatccct tgacttgttg caaaatctgc aaaattccac
     3961 acttgttcac caacaaaatt ttcacatgta tctattactt cgtgatttgc ttcgtaataa
     4021 gccacttgat actcttctgt aaacattgtt ggtactgtat catgaaatcc agctactgta
     4081 tctgctccat attctgtaaa cattattggc gtatcaggac atctttccat ccatccatct
     4141 agctcttttt tcaacagata ttttgcatgt gccagatccc ctcccgaaac ataccaacca
     4201 taataacgat ttaaacataa aacatcgaca atatctccta ccttacaaac atctggcgtt
     4261 gattttagat aagtaacgat tgttacaggt cttttctgcg gatcaagttc tttagttaat
     4321 tcaactaaag gttcaaaata ttctttagca ccttcggaat ccgaatctgg ttcatttgca
     4381 atagaccaca ttacaacact tgggtggttc ttgtcgcgtt ctatcaattc cttgatcacc
     4441 gttttatgag aattttctgt tcgtatctct ttccacgtat tatgtttttc cacattatca
     4501 tctaataaag tggccatgaa atttaaatgt aaccctactg caggtacttc atcaataact
     4561 acaatacctt ctcgatctgc taatcgcata atttcttctg agtaaggata atgtgatgtt
     4621 ctaaaagaat tagcacctat ccatttcatt aaattaaaat ctttaatatt tacagcctca
     4681 ttcaaaccac gtccattaac atacgaatcc tcatgcttac caaatccttt aaaataaaaa
     4741 ggtttattat taatcaaaaa tttgccattg gtaacctgaa cactgcgaat accaaattct
     4801 tctgtatagg tatcgatcac tttattatca tcaattaaac taattttcat actatataaa
     4861 taagcgtcta gaggttccca aaaaattgga ttcttaagct gaatcattcc tttctttcct
     4921 tcagcttcag ctacaagttg agcctcttcg tcatatatcg ctattaagat ttttccggtc
     4981 cattctgtat cgatattgaa ttctacactt gcatccaaat cagttattct tgtattaata
     5041 gtaatatcac ttatatagtc tttcggagtt gtatataact taacaggtct atgaatacct
     5101 gcataattga agaaatcaaa attaactaag ttttcctttt ttatatcccc attttcctgt
     5161 actgtttcct tcataatccc cacaggtaaa gtactatcgt caataatatt gtttacagca
     5221 actgtaattc gattattccc gtcttttaca aaccgattaa tttcagactc aaatggtgta
     5281 aacccacctt tgtgttgagt aataaacttt ccattcaaaa aaacttttgc ttcatgtgtt
     5341 gcagatccaa aacgaagaac taatctttct tctaataatc ttttaggaag agtcacttct
     5401 ttttcatacc acacccatcc aacatgattt ctaatgttct ctgtttcaaa taaatcatta
     5461 taagaagagg gaactgaaat cggataactc tctttttcat ttattggttc taaagcaagt
     5521 tcttcctgta agtcatcatt tgtatctaat ttaaatctcc agagaccgct taagtcaatt
     5581 acttgcctcg tctctgtcat aatgggatac aacatataaa ccactcctat ctaaatatta
     5641 aataaatgta tcctttaaac cacaataagc atctattgga cttactccct taaattcaga
     5701 aagacccatt agtttgtcca ccaatatttc taaagtttct tgttttccat cataagtatt
     5761 aatataagtc tttacttgag gtacatcagc caaatgaaac ggacactgta cagatacaaa
     5821 aattgttgga atttcatgaa tgtaaaacgg tatatccgga gttcctttac ttgctggcca
     5881 gacaattcgt tgaactgtgc ctggattaac attagctata ttaatgatca agtcatattt
     5941 tttagttaaa tttttaattg gtctcttagc agcatatatt ccagctatat ttttaatttt
     6001 ttcttcttgc gataatcctt tcaattcttc ttcaggtgaa atgtattttt caacttcaaa
     6061 tccttttgct gacaaaatct gtttcaataa atcaatggct tgaggtctat ttccagcaac
     6121 tacttcacca aacccacctt ttaccccatg tacatctact agtaaaatcc ttttatattt
     6181 ttctggtaca ataggccaaa tatcttgttt atctttaact aatgtaattg cttggtcagc
     6241 cacctcttta aaaattgatt tattttcaat taaaccaatt ttttccagag cttcttgctt
     6301 aggtaataaa atttgttctt ttgctttttt gtgtaatccc aatttagctt ttaaccctaa
     6361 aattcttttt aaagcatcta ataaccgatc atcagtgata attcctttac gatagccttc
     6421 catcatataa ttaaagtctt catctggatc attaaaaaat agaaatagat cacatccagc
     6481 tgcaatagaa gtgggcaata attctgatcg tttcattgcc ccagtcattc ctaacatatg
     6541 actagcatca gtaactacta atccattaaa tccgagtttt cctctaagta agtcagtgat
     6601 taattctttt gataaagttg caggaagtaa atcttcatct ttcagatcag gattaaaatg
     6661 ttttgaataa gctggcatat ggatatgacc tgccataatt gaaggtaatc cagcttctat
     6721 taagcctgag tatacttttc caaaagaatt atcccattct tccgtaccta aactattaat
     6781 actaaaagat agatgctgat ctcgttcgtc aataccgtca ccagggaaat gtttagctgc
     6841 aggcaaaatt ccactctcct gaataccttt catataagct aaactaagtt ctaaaacttt
     6901 atcagggttt tgtccaaaag atcgactaga aatgatagga tttctccaat ttctattaat
     6961 atctacaata ggagcaaaac tccagttaca tccaatagcc gatgcttcaa tcccagaaac
     7021 tctccctaat tcataagcat atttcgcatc atttgttgca ccaattttta cttctacacc
     7081 aacttcagta ccatctgtac aagctccgtt accacctgct tccgtattag cagcaattaa
     7141 tagaggaatt ttactttctg tttgtaagat atagttttga tcatatacct catcagcagt
     7201 tcctggatta tatcgtacag ctccaatatg gtactgattg accatattac tcaagtaatt
     7261 tttatcacga ctagatccca tattaacaaa caattgacct attttttctt ccaaagtcat
     7321 agaatcaatc gtctcttcaa tccaagaaat agcatcttca tctaaattat atggtttttt
     7381 tcgtaaatct acttttatag tcattttctt tctcctctac ttattagtaa gatttttcca
     7441 aaaagtatct atatattttt gttcaatatc tacataatct cccgataaac atttaaataa
     7501 aacatcagtt cttaagtttt cccatgattc tttttcttta ttgaccaaaa taggataaaa
     7561 gaaaacttta tttttatttg cagcttctag atcaccagga gaatcaccaa tcattaatat
     7621 cttatccaaa tcacaaccat tttcaattac acttcgaata atatcttctt tttttccttt
     7681 atcttgacaa cacagttcat caactaatga taataattca tgtctttccc attcttcttg
     7741 aacagcttcc ttattagctg agcttacaat aattatcttc ccatattttt tcagagcttt
     7801 tatagtatct ctagcactta aaaagggttt atctaatcct tttgcttgac taatctgttg
     7861 attgacttct tccgaccatt ttaaagcttt taataaatcc tctgactgag aatattctat
     7921 ttccctcttc aaagatggat tagacaattc ttttgttaga gatacccagt gctttaatcg
     7981 attaatcgat gttacatcat ttttttctaa tgttttaact aaacctaaaa atctgtttat
     8041 tccacgagtc tctgaatata aattaatatt attccaatcc tgtaggaatt tttctctatg
     8101 atgaacatca aaaatctctg cagcaattgg tccgaaaaag agattgtgtt tataagtcat
     8161 cgtatccata acacagccat ctgaatcaat acaaaatatc caattattca tatttctctc
     8221 ctatttatgt ttttgtttta aaagctcgca attttctaag actttatctt tagataatgg
     8281 ataaaggaaa aataaaatta atcctacaat cagaaaacaa attgatggaa ttaatgttga
     8341 agcgttatat aacttttcta aaacatctcc cgtttgtaca tttgctaaag agtcatagcc
     8401 tataatagaa agagtccaac ctccgacgcc tccagctaga gcttgaccta tttttctagc
     8461 aaaagaatat accgcatata cggtcccatc ttctctttga tcagacttta cttcttgatc
     8521 atcaataaca tcagtaatat ttgcccaaat aacagtatta aacacaccca aacccatata
     8581 gccaaccgaa ctaagaatta agaatacata catattacta gcttttatca aaaataagat
     8641 caaatatact attgctgaaa agaacattcc tactgatgcc agttcttttt ttccatattt
     8701 tttacttaaa aacaaagtta aaggcgaaac aactattaaa accaaaatag gattgataaa
     8761 attcattaaa actattccct gtgcatcatt atagtaatca ggaaatacat aattattcat
     8821 actcataatt aataattgag caaggagtaa gaaaatagcc gcaccaatta tagaaagtaa
     8881 tgccctattt ttaactaacc cttttaaaga ttttaacaat gaaactttgt attgagattg
     8941 gtcaattctt actcgttcag tagttagttt ataacatatt aaataacaaa taagtgcaca
     9001 tatcgaaaat attcccgcaa caattgtaaa agttgatcca ccacgaacta tttgagcgcc
     9061 tgaatcatct cttgtataaa taaataatgg tgttaataca ccaatgacca aacttgctaa
     9121 agtagctcca acatttcgga atgtcgatag cattgttctt tcttctgtaa tagaagtaat
     9181 agctgatgcc attgatccat aaggaatatt tatagatgtg taaaaaatac tcccccataa
     9241 tatatacgta acatacatgt atactacctt aacgctcata gaagctgaaa tcatagaagt
     9301 ttgatacatt aaaaaacttg ctaaagcgac tggaccactc attcttaaaa tccacggttt
     9361 aaacttaccc tgcttagttg ctttcgatct atcaacaata cgccccatag ttacatcagt
     9421 aactgcatcg ataaatcttg ctactaaaaa taatgttcca acggcagctc cgcttatccc
     9481 caatactttt gtataaaaga tcattaaaaa agaactagca aaaatgaaag taaaatcgtt
     9541 tccaaaatct ccaaacatat atcctatttt gtctcttata ccaaattttc tttccataca
     9601 attctctccc ttctgttgtt aagcgttttc attctgatga aagtacgtac tatactctga
     9661 agcgtaaaga gtcagtattt attttttaca tttcagagta ttatttgttt tttctcctaa
     9721 taattcttta tctcataaaa cttatctata tatttactag ctactcgact tacttcttca
     9781 aaatcacctt tttcaacaga agccaataaa ttcccaccta caccaactgc aacaactcct
     9841 acttcaaacc aatcttctaa gttctctata cttactccgc cagtaggcat tatatttacg
     9901 tgtggtaatg gagcttgata ggcttttaca atggatggac caaaagcaga acctgggaat
     9961 agtttaatga tatctacgcc agcagtaagt gcctccttta tctcagtaat tgtcatacaa
    10021 cctggtaaat aaggaatttg atataaatta caaatctcag ctgtttgtcg atcaaaagat
    10081 ggactaacga tatattctgc cccagccata attgcgatac gagcagtaaa cgcatctaaa
    10141 accgtaccgg ctccgattat tacatctttt tgatcagcat attttttagc aatttctttg
    10201 attatttctt cagcattagg aactgtaaaa gttagttcaa tccctttaat tccacccgca
    10261 ataattgaat ttattgcttt aatggcctca tccttatttt tcccacgtac aaccgcaatg
    10321 actccagccg cttctaactt acttaaaatt tctacttttt tcatatctat ctccttcctt
    10381 tatggataca tactttgtct agctgtacta acttacaaag aataaattta agcttttatt
    10441 tcaagtatta ttttctactt ccgatttcaa aaaaattaaa ataattatac gcattacgat
    10501 aacaaatatt ctccactatc tgactaagat acatttcatc atctggaatt cggcctgctt
    10561 taacccactc gcttagtaat tgacataata ctcgacgaaa atactcatgg cgaggatagc
    10621 ttagaaaact tcgagaatca gtcaacatac ctgtaaaatt cgacaacaaa ctttgttgtg
    10681 ccatcgtagt caactgttga cgcattcctt cagctgtatc attgaaccac caagcacatc
    10741 ccaattggat tttttgaatc ataccccctt ggaagctttg cattgctgtt gctagtggaa
    10801 gccaatcagt tggatttaat gaatataaaa ttgtttttgg taagcaccca ctcttttcag
    10861 cggtatcgaa caatgctaca acattttgtg tcaaactagc ttgatccccc atcgaatcac
    10921 caccgacatc tactccaatt tgttccttta atatacttga attatttctt aaagcattta
    10981 aatgcatttg catcgtccaa ccatatcttg tatactcaga catcaaatgt aattgaatac
    11041 ctgtaacaaa ttgtgcaatt tctgataaat ggaaatccgt ttttcctgct aaagctttta
    11101 ttaacagatt gtcgagtatt ttttcatctg ctatttcata aaaataagta ttcaaaccgt
    11161 gatctgctaa tcgacagcca atttgatgaa aatgatccac tcgttggctc aatgcttgct
    11221 tcaacccatt aaagtctttg attggtatag ccgctgtttg actaagtttt aaaatatagt
    11281 tcgaaaagcc tgatgatttg atactccaga ccttatctgg acggaaagta ggtaatacct
    11341 tgaaagaatt atcctgttta gaaagctcag tatgatacca caagtcatct gtaggatcat
    11401 ccgttgtaca gatggctttc acatccatca tctccaacaa ttctttcggg cgataggaat
    11461 ccgtttgaat tttttcgtta gcacgtcgcc aaatttctgg tgcattcttc tcagaaattg
    11521 tcaaatcaat atcaaagtaa cgttgtaatt ccaaatgaga ccattcaaaa ataggattac
    11581 ctggcgcctt ctccactgtt tttacaaaag ctaaaaattt ttcataatca tcacctggac
    11641 cactgatcaa ctcttcttct ataccattag ctcgcatcaa tcgccattta taatgatctc
    11701 cagctccttt atcatttaac catacctgag tcaaattctt gtattgctta ttttctagca
    11761 aatatgctgg gtctaaatga caatgatagt cgataattgg ttggtgtttt gcaaatttat
    11821 gaaaaagtct tttagctatt tcattctcta ataaaaagtt cttatctaaa aacatattta
    11881 aacactcctt tccttccgtt agtttttaga agagaaaatt tttcctctaa ataaactccc
    11941 ttatataatt atttactcgc ccccttttca agcgcttccc aaataccatt taaataaact
    12001 gcacctagag ctcggtcata taatccataa ccaggtctac cggtttctcc ccaaatcatc
    12061 cgaccatgat ctggacgaat atagccatta aatccattat cgtacattgt ttttaatatc
    12121 ttatacatat ctagagaacc atattctgat ttatgcggcg cttcgtaaaa atcgagtcca
    12181 ttgtcactta aatatttgat attacgaaca tgtgcaaaag gaatccgatc ccgttgacaa
    12241 aattcagata gaatttcata gacatcatta tctggtcgtt ctgcaatact tccagtacat
    12301 aatgtaatac cattagaagg agaatccact acattacaca accaatctaa atcgtcacga
    12361 tttttaacaa tacgaggtaa tccgaaaatg gaatatggtg gatcatctgg gtgaactgcc
    12421 attttaatcc caacttcttc acatgccggg ataattgctt tgagaaaata tgcaaagttc
    12481 tctcgtaatt tctcttcatc aacttcttta taggcttcta ataattgctt aatttgtgat
    12541 aaccgatgag gttcccaacc cggcaattca aaattattag tagaattttc tacttctcta
    12601 ataatttcct ccggatcagt agggatattt tttgaaatat aggctaacgt agaagaccca
    12661 tcatctaaac gataatccaa atccgatttt acccaatcaa atactggcat aaaattataa
    12721 cagataacct caatcccaaa ttctgccaaa ttgcgaatcg tctgtttata attctcaatg
    12781 tattgatctc gtgttggtaa accaattttg atatcatcat gaacattaac actctcaata
    12841 actttcaagg taagtccatt ggcttcgact tcatctttta aagatttaat tcgttctctc
    12901 ggccaaacct ctccggctgg tatatccatt aatgttccaa caattccttt cattgctggg
    12961 atctgacgaa tttcttgtag tgagattttt tcttcatttg ccccatacca tctaaaagtc
    13021 atttccatag ttactttcct ccaacttctg ttatatattt attgattgtt ttacgaactg
    13081 cttgaggacc tactagcatt tcgcaaaaga ttttttcagt tttctttcct accccaactt
    13141 gatataaatc taaaccaaag atttctttat tttctaaaat ttcctgtacc gcacaatgaa
    13201 tctttgaagg atcttgttca cctaatttca atactgataa tttatcctgc aactctacca
    13261 ataacggatc aggacttggc acaaaatttt ccccttgatc atcgactgcc agtaaataac
    13321 gtaaccaagc agcaatagcg ataggaataa atgttagatt ttctgcattt ccgtcttttt
    13381 cgacatactt tttaattgtt tcaccatagc gaatcgctac tttttgagaa gtatctgttg
    13441 caattcgttg tggtgtatct ggaatatagg gattaggcaa acgtttatta attacttcat
    13501 caataaattg ttttggatca ataatgcctg gattttcaac tactggtaaa ccttctaaat
    13561 aacctattcc tttgattaaa ccaaccaaat catcatcctg catctctgct gaaattgatt
    13621 gatatcctag cagacaacct gttactgcca aagcagtatg aagtggattc aagcttgtcg
    13681 taaccttcat gatgtctgct ttatcaaccg tctctctatc tgtcataatc acaccagcct
    13741 tttccaattt aggccggcca tttggaaaac tatcttcaat aactaaataa tgaactacct
    13801 cagtattagt gaaagcagca atattggtat gtttttttgt gtgaatgata tctaaatcct
    13861 cgagccccat catcaataga tcttccttta cattctctga aggatttggc gtaattcgat
    13921 caatcatact ccaaggaaaa gtcacttttt ctttatcctt taaataagca ataaattttt
    13981 cagaaacata tccttctttt tgccaagctt ctgcaatcgt aaaaatacta tcttgaaaac
    14041 gttgaccatt ctgtgagaaa ttatcagtag aaaccatcgc aatcggcaac tctccagcat
    14101 taaatctgct atataacaag gatgttacaa tactcatcgt atgttgagga ttgctaggtc
    14161 cagatttgat atcagctttg actaccgaaa agaattgccc tttagaatct tttaaactgt
    14221 aacctttttc agtaatagta aacgttgtaa actgtaattt aggatcttca aaatatttaa
    14281 ccactctttg atagtccgct atattcttcg gattgcaata taaactatca gccgttactg
    14341 ccaaaagtct ttttttgagt tcaccatctc cactcataac aatttccaaa atgtcattgt
    14401 tatagtcatg ataagctttt tccactactt cttcatcaaa tgtttcacac acaactactc
    14461 ctgtttctaa ttcattttga tctgctaagc attgagcaat ttctgcatga aatcctcgat
    14521 aaagatttcc tccaccaaaa tgaagccata ctggatgttg ctggccttct tgcttaactt
    14581 ctttgacatc aaaacacggc agtagaatct gcatttcatt gaattcttcg atagaatttt
    14641 gccaattttt aatcgaaacc ataattaacc tcctcaaact gatatgttag ttttgataca
    14701 ttttatattt taaaacccat tgtaaccgtt gtcaatataa aaagggaata aacttgcttt
    14761 tttctaccat atcagaatga ttgtattttt tattcagaaa aataaaatac tccttctttt
    14821 tggactgatt ttatcgaaac ttattttttc tttttttcat gtattctttt atttttataa
    14881 ctagtgtatt acttcaaaat ttgatattat atggcatgaa cagaattaaa atatcagtta
    14941 aaataaaagt taaggagcat tgtgtatgac aattaaaact agtctccaaa atcaagctta
    15001 ccaatctatt cgccgacaaa ttatctatgc tgacttagaa cctggaaaaa aagtatcaga
    15061 aaaaaaatta gaagaaacac tttctattgg tcgtacacca atacgtgaag cactgattca
    15121 actccgacaa caaggtcttg ttgatacaat tcctcaaagc ggaaattata tctcattaat
    15181 tgatttagat tcggccaaaa atgctcgatt tgtcagagaa catttggaac gacaaattat
    15241 gttagagtgt tgtgccaaaa tgaataacca aaaaaaacgg attttagaaa ctataatttc
    15301 agaacaagaa aaagctgtta gtcaaaaaaa tgctcgtagt ttttttcata atgataattt
    15361 attccataaa gcttgttttg aaattgcaga gcgagaagaa gtatggcaat ggttagaaaa
    15421 taacaataca cacttagaac gatttcgatg gctacgagta aaaacggaag gattaaagtg
    15481 ggaaaaaatt atggaacaac attatcaact atttgaggca ttaacaaaac aagatccaga
    15541 agaagctaac tttctaacat cgttgcatct tcatttaatg cttaatgagc aaaatattgt
    15601 tttagctact catccaaaat atttcaaaaa tatataactt ttaactcttt ttaaattaaa
    15661 tggttgttct gatcagaaaa atatcgcttg ttttcttatt atgtaatata tttcataaac
    15721 tattctgcat aacaactatt gtttgtactt tttacattgg ataactaatt atgactgctg
    15781 ataacttttg atattaaact agtatctcca atacaaataa aaaatagata tcttgttcat
    15841 caaaattagt tcgtggatac ttaccttcat ttacatcatt cagcggtttc ccattttctt
    15901 ttattctatt atttcatttt ctaatagact tggcttcatt tcgcaatact ttttttcaat
    15961 aggcatcaaa ttggtgttgt ttagatattt agttgtagtt ttgtgacatg ataagtatgc
    16021 tcctttttct cttttccact aatacaacga tcaaagggtg cttttttcaa aaaactagaa
    16081 aaatcaaaat aagattcgta ttttgattct atatatcctg tttcaactac atcttatatt
    16141 tcacaataga ataaatagcc ttttgcatag ctgcttaact tataagaaat tgcaatttac
    16201 ttcttcaaag tgaaaacgaa tatgagtaaa ataaaattat tcttcttaca gataattaaa
    16261 aatagcgcgt aacaaaaatc ggcattcaat cacataatta ggattgatgc cgattactta
    16321 tattctacgt atagttttag tattcttatt ttttatcacc agtaaccaat tgagaacagc
    16381 cctaaagcag aatagtcttt tatctcaaaa cgcttaattt caggcttagg aatatgaata
    16441 atcttttgag tatattcttt ctcttttaat cttactgaag aaataccact gcctatcttt
    16501 tttacaaata tttcatttgg tgtacagact aataaaacaa tatttgtaat caatccttgc
    16561 actaaagaat taaaaggaag actatttaaa acagggtgtg cataactata acatgtgaag
    16621 tagttatttt gaactttaac ttttaaaaac tttaaaaata atcttatttg ttcttctaaa
    16681 caatcatcta tactcatata atcactccac taattaatct ccccaaaaag acacagcatt
    16741 aagagatata ccaacacaac agtgcaaata actctacatc ttccttcgca accttatttc
    16801 aataaaccat aaaaattatt ttttaataga aactgaaaat taaaactaga aaaagtagtt
    16861 ttaccgaatg taagagcatc atcaccatca atatagaaat acattctttt ccagttacat
    16921 ttaattttta aacaaaattc tccccaaaaa ggaacttttt ctagtgaaaa cttggtaatc
    16981 tctttgtaat taattcttgt taaagaataa ttaaacactt catttttact tgttattttt
    17041 tcattgacta taactagttc atctggtaaa aaaattaacc aacaaacatc gacaaacagt
    17101 aaatgatata atccatttcc acctccaagc atattcaata ctggtgaaca tgccttagaa
    17161 acacgaatat agttatggtt taaatagata ttttctttaa acattgcttg tttaaaagcc
    17221 atatgctctt gttctaaact tttcataaac ttttactcta atgcacagct agcagcagct
    17281 gctgcaattc ctgctacaat atttacctta gctaactctt tagctgcagc ttttcctaat
    17341 tgtttttctg caatttttaa taataaatcc gcagcttttt caaaattaaa agcttttaat
    17401 gcttcaataa aatctccctg cgtacctata gcccaagcca ctcctcctcc aggaagagaa
    17461 ttaatggcta cacatccagc atatcgtttc caatcaactt tctccattct aggaacaata
    17521 atatgttcat aaaagactct tgctgctctt ccttgttcgt tatcttgact gattcgttca
    17581 cgaatagcac caaaatcctt tatatggtat acaccatgtt cgtctaaaaa accaactgta
    17641 tcaaaataaa aagttaattc atctactaat ttattcttta tttctaaatc aactgtattc
    17701 actttttctg tggcatacac acttgttcca gtactaacaa aagtacttaa acctaataag
    17761 aaaacaccta aaacaccaaa tattttaatt attcttttca taatttctcc tccataaaaa
    17821 ataagttact ttttaaatat cttgtttatg aattcattcc ccaaaggcct tttaagattg
    17881 atacagcagt ccgttcactt cttttagact tgtcatacaa gtcttttaaa tgatcccata
    17941 tcagactagt ttgtctatct agcttcaatc cattaaacgc taatgaacgg ttcatttttt
    18001 ctattacttt agataaagct acagaaattt ttataccttc acaacgcgca tcttggattt
    18061 caataatagt atcatcaatt agtttttgaa tttcttgcct atcaacatat tcaatcttag
    18121 aaagagaatc ttttaaagct actaatgatt caacgatttc ttttttctct tcagacattt
    18181 tcttcctcct tctagtgacc cgtaaagcca tgtagagcag agtccattga accagtaatt
    18241 acactatcta caacgccatt ccaatttact ctacattttc catttttcag atttgtcggt
    18301 ccatacggat agcctttttg acattcaatg ttcggattat accagatagg attataccat
    18361 tcagccgcag aagcagattc agtcgataca aacaatccca caccaacaaa tccaatacac
    18421 atcacactat agccaattag ttttttcatc tcgtatccat ctcctaaaaa atagaatagt
    18481 tcttatagtt attcataaga catatttttt ccgtttttgt tttatccttt ctgtcctata
    18541 acaacttttt tcaagtaaag aatgacatag tttttcttaa aaaaacagtc tgtttttttc
    18601 tatttcttcg gtgtataata aatatgagtg ttcatttttt attttaatac gcactccgta
    18661 cataataaat cttgatcgca tcaatctttt gagcttcttg atctactttc aattgaagta
    18721 atacaaattg agtaacctta ttcattgttt cttctccaaa taacaaatat tgatccggat
    18781 tctctatatc ttgtgtcacc tggtaaagtt tcccagttgt tttcatttgt acatgcgggt
    18841 ctacatcaat actattgtct ttaatacaac gatctgtcat atagtccctc acagcttgat
    18901 tgcgtttata aacatctgtg aaattactcc attttctagc aaaatctttt aagaaatttt
    18961 ttgtcatttc atctatttgc atttgttgcg ctgtctcgtc ttctaatgaa ccaatttgac
    19021 tgttactttc agtactttga agagttccac ttgtttcttt tactgcttcg attgtttctt
    19081 ctgtcgttct caattgtgtt ttttgttttt cagaagaaaa ccaatgacaa ccagtaagac
    19141 ctatcaaaca taaccaacta aatactaaaa ttatcccttt tttcacgttt ctagtcactg
    19201 cctttcttat ttcaccttac gaaccagact acgaattttt gtttgattgt acgtgcgttg
    19261 ataccgagcc ataatccgtc cttgctcggc attctgttcc acactagaga aatgttgtcc
    19321 gccatatgaa acatctgtta taattccggt gtgaccatag attccaggag acaatgcacc
    19381 acctgcttgc caattcacca catctcctgc ttgtaaatca cttggttttg ggttcatgat
    19441 tacttgccaa ccataggttg tccagttata atcttcccct attaacatcg caaacatgtg
    19501 tccagaaccc attaactgtg ggccacctaa ttgagataca taccatgccg taccaccata
    19561 acattcccca ttatttacgg atcgtccaat gatccgatcc aaaaccttcg cattgccttt
    19621 actttttcct gcaataagcg aagttttttt tgttggtagg ctattccaat gcttgatcgc
    19681 aaaagtatca tattccgtta agttatagga cgttatgata ctcattgctc ctcgataata
    19741 cggactccct tcggtaatac ctgctgccgc atagcctcca cgacctagaa tcaataaaca
    19801 acttccagga tctttattgc ccacacattg attaaagttg ctttggctcg ccaccataaa
    19861 gccataatag tcataacaag cttttaagtt cggaaacttc atatagaaac caccttcaga
    19921 accaccaatt ccacgtgcag aaccttgtgg gtagggacaa ccaggaaacc aggtaatccc
    19981 aaaaaagttc gtatcgtttc ttccagattg tgactgtcca taagctgatt catagcctaa
    20041 ttgagaaaga atcacactcg gtaataactg atactttaca gctgcaccaa ctgctgcttg
    20101 cgcatgttca tctgtgattg gaccacgtcc tttaatctct gaaaaaatcg gtaatccttc
    20161 ggtatattcc ccattaaaag cgacagctag acctgtagct tctcctccat gctcagaaag
    20221 ttctcctgaa aaaaagaatg gcaatagaaa aaagggaaga ataaagaaaa gaagacaacc
    20281 tagacaccct ttcttcattt cttcctcatc ctttcttcga taatggtttt tggactgttc
    20341 gtccttttgg taaagtaaaa tcagttcctg gttttgcgtc caaaatcggc agtgttttag
    20401 gatccttttc tattttttcc gattgctctg ttggcttatc taaagaagaa aatgcaggtt
    20461 gtaacgattt tggtgcggaa atcgacggtt tactttcaga cgaacgttgc cccggttgtt
    20521 gcacagaacg atttcctgat agagtggcta ccgacgaatt aggaacagag tattggttca
    20581 ataactgctg cattgctgga taactcccat ttttcgcctg atttttcact tggcgaatct
    20641 gttgtgaaag agaaccagca gctgttaatt gtggcacggg tacttttcca gaaggcaacg
    20701 gaatcgattg accaacaaaa gcgatacctt tatttaacaa tggttttctt tgattattcc
    20761 cttgttgctt actcaattgt gccaatgatt gtacctgttg ttttggtctt actgaattca
    20821 tggacgaatt tggaatcaaa ccatttgaaa gaccagaatt ccactctgtt ttcgatttgg
    20881 tagaagacat ttcaggctct accccatgat aacgaacatg acgaccacta taaggcaagg
    20941 cttgatttga acgcccacct agttcaaagg gattaaccac ttgcctccct tttaccgatt
    21001 cttgtggtgt acgtttttgt tgaaactttt gaaatccatg tatcgctgca gaagcgagtg
    21061 gattcgttgc tcgatacaca ttccctgcta atcctgcacc tttgattgcc aaattttgtc
    21121 cagcagttga tagttgacca ggcagttgtt tcatttgaga caaagaatga cttgctatgt
    21181 ttttcgtgtt gtttatagtt tgatctgcag ctcctaaccc tagtttcttt aataaatctt
    21241 tccgttttac aatgagtaaa attgatagga gtgctttgac aaacatattt cctaaaaaac
    21301 caaaaacagt attcattgga attaaatcgt ctactatgtt atagatcaaa aatgccacca
    21361 aaataatcac actgtaaaaa gatttttgaa acatcaagcc caaaaaggac tttaaggtat
    21421 tcatgagcat ataatcaaat actggaacaa aagaagcgag taatgaaaaa ggaatcacaa
    21481 gtaataaaca caacaccaac atttgaaaga taaaacgaat catgccaatc actacaagtg
    21541 gtaatccaat acttagatta agcaatggca ccatagaacc aacgactgct ttataaacag
    21601 ctttagttgg ttgaatatag acacgataag ccttcttttt ccctctatct tctcctgcag
    21661 cagtggtcac ttttgtctca atatcagata attcttcact tgacgcttcc ttggctagaa
    21721 attcttgtgg ttcaatctct gcttgataca attcttctaa atttgttgtc ccataattta
    21781 acaatatata cggatcaaca acagccgctt tataataaag ttggcgcact ttttgaatgg
    21841 cttccttttg tgtcgttggc actaaaacac cattgacatc ttttgtcgcc aattcatcta
    21901 gactatttgt agcagaaaaa ataaagcctt ctacctccac ggacaaatca tttaaccctt
    21961 tggtaaaagc ttctccttta ctaggtacgt tactaccata gccaaaccaa accattgaaa
    22021 aaatgacaac gaagagaaat cgaataaaca ccatttttgc gtaatgtttc cctctaaata
    22081 tacgaagagt aaatagatat aacacataca agacgacaat ccccgcacca ataggatcgt
    22141 atatttttga ataaatagta tccgaaaaag tgaaaaactg gtgaattaac tcgttcattg
    22201 cagctccttc atagagcttc tcaatgacaa aatcaaggcc ttgccaaatc aatttactta
    22261 aactaaagaa catattcgtc atcattttta gaaaatctgt gccatttgcc ccaaataaca
    22321 ttttgcctaa tgaaaattca ctatcagata aataagaaga aaaggtatca atatgaaatt
    22381 tcccaatctc atagatcgat tgatccacct gcttttctgc cgcatacacc aatccaccaa
    22441 caaaaagcag tccgaatcca atcgttaaaa aaaacaaaac gcaccatttc ttttccttat
    22501 gctttatata agccattgtt tcacctcatt tctattgcat gattaacgta tcctgttctt
    22561 ctacttgaga gtgacttgtt ttttccgttg tttgtaatgc agcggtcatt tcttcaaaca
    22621 aactgtgtac attgagtttt cctacacgtc catagggatc taacatccaa cactgtcctt
    22681 taatcatgtg gctcatttca gctaagttcg cttcatttac ttccaaacgt aaatgattca
    22741 aaatcttttc tcgctcactg tcttcatcaa aagcaaagac gacaccaaaa ttcccttttt
    22801 ctttatctga acctaagtca ccaataaatt gtgtatctaa cactaattga ttcatctggg
    22861 aacgccccac acgtgccatt gctgcaataa tactacgtcc tgcgttcgaa ttattaaata
    22921 cccatgcttc tgtaaaataa atcgctgttt tcttactact atctcgtttt ccaaacattt
    22981 cacaaaaacg acctaaacta atcatcaaac acaaagactt tcgatccgca tctgtatata
    23041 gttctggtcg gacattgtca tttggtaatt tcaaatcttg gatctctaaa atcgttgttt
    23101 tggcattaaa gtctaatccc gggttttctc cataagaaaa tcctaaacgt aaaatcgaat
    23161 cttctaccgt caagcgtaaa aactcaccat attctcgaac ctctttttgt tccatttgtt
    23221 ctaaatagtc gaccacatgc atcaagccaa cttgttgtcc ggcttctttt tgaactaaaa
    23281 cttcttggat tccctttaat accgcccctt ttaaaaggtg attggtacct aacggactta
    23341 actcatcaat catatcctgg gctacttgtt tcgcatctac tcgggataaa caaacaattg
    23401 gatctaatac accataatta cggggatttg tagcatctaa cgtgacataa ctcatttttt
    23461 gcaaatgttc tacaaacaaa gggtaatgtt tctgataata cgggtcttga atgagtttcg
    23521 taaaccattt gcgcttttct cctttgggat ccacaaataa actttgtaca ttcataaacg
    23581 aactatacaa aaagagcaag ccaactaaaa aggtcttccc tttaccggtt tttccagtta
    23641 ctgctacatg aggcgcatca aacaacgcac ctttgattcc ttccgcaatg gctagaagat
    23701 tcaaaaagac aaaacgattt gacgcataaa ttaattcttc taatggtgtt ttttctcctc
    23761 gagaaccacc atcccctaat gtatcttgcc gaccaatata ccagccggat tccataccta
    23821 attctgatac tgctgaaaac aaccattcgc caactgcttc tacagttgtt cggtgcttcc
    23881 aatgtaactg ccgtcccaat ggttgcccta ataaacattt atagaacaat tctcgttgat
    23941 cattttttgc acggtggata tggataatcg tatgaagttg ttgaataacc gttgcactat
    24001 tttgacgaac ttcttcaacc gtttgaccgt atacaataaa acatgcgatc caatcgacga
    24061 caggttgccc attatctact cgttgcttta aatgttttac taatcctcga acagttaata
    24121 agcgttcact aggttcttca tcattttgaa ccaattcctt atgctctgtt ttgaaccgtt
    24181 ccgatagcca attcagtttt aaaccaatac ctccctgtcc tttcaagcgt ggatagtgaa
    24241 ttttcattcg caattctgct gggaaagaaa gatcctgagc aaattgaaat agatcacaat
    24301 ttctcatatt ttcaggtgtt tccccaatag gcaacaatgc taaataacta ctccctaact
    24361 catcttctaa ttgaagaagg cctttatgtt ccttcggtat acgtacatac gttccttgat
    24421 tgtctttcag tacttcccaa ttattttgtt cttctacttt gtgagccatt cctcgaatat
    24481 attgcagacg attgagatac aacagctctt tttttactaa gggacgaata gaaaagctat
    24541 aaagtaattg tgtcacttct tttacataag gatcactttc agaaaacaaa gtttccaaat
    24601 catctacttc taatccaaat aagcgtgcta aacttcctgc taaatctaac cagattagat
    24661 ttattacatc atgaaaactc tccaccgttg ctttttcttt gactttgatt cctaaaataa
    24721 atgaaggacg atagacttga ccttctcgtt ccaacaatgt cactgtttct tttgcataat
    24781 acgcaccaat tgcttgacta tcgggagaaa atccctttcc taatgtgtca aacttcgtcc
    24841 gtaaattcat tgttcgtgga tacatcacca actccacatc ttcataatct gctaaaagca
    24901 acagtaaacg agccatcatt tcttttattt cctgtgtctt ttttggtgtg ttttttgaaa
    24961 ttgttcgtgg aaaaacatga tagtaggccc agatacaatc ctctccattt aacaaacaat
    25021 ttttcttgaa tgcttttact ggttctttta caagcaccaa tgaatttcac ctcccaataa
    25081 aaaaggaaca accagttgat tgtccctttt tctaatcctc taaataaaca tacttattca
    25141 caaaaagtaa ttcttccaat gcattgtttg ataccttgtc ccagttataa tacacacaat
    25201 caccattcat catacgaatc atataacaaa accaatccca taaataaaaa tgcacttttt
    25261 ttccatcagg ttttagtttt gccagtgcta acacacataa ataggggagt cctatataaa
    25321 aaacaactcc tgctggtgga aaaaaagaaa tgacccaacc aataaatgaa cgtaaaaata
    25381 aatattcaaa gattacgacc aacaaaaaag ttgctgcatt gactaatgca actggaaatg
    25441 gaagacgcca attgcttgta atctgttgta cgcgataagg ttccgcataa acaatcgaat
    25501 aatcataagg ttcccaatcc acttcactat cctcctaatc cataaataat ttttcaatga
    25561 ttttaccaaa cgcatcaaat acacgtgttg gatcatttaa gaagaaataa actgcggcac
    25621 ctgctgcgat agatattaat gcatttccta cttttgattt cataaaattt cgcaatccca
    25681 gataaacaac caccattatt aaaaaatagc caccttgcgt taatataaaa tctacaattc
    25741 ccttcagtgt catttccgtt cttctccttt cctatccaac caattatgtg ttaatttttc
    25801 aacataatac tgatttgttt ttttcgtaat gacaatcgtc atttgttctt tttgtaaaag
    25861 tgacgtatca ccatctcgaa agacgaccgt tgcttttaca ataaaaggtt ttttcgtttc
    25921 tttataacgc aatactttca tctctacttg atcaacttta gctgtttgat tgagtccttc
    25981 aggttctttc atcatgtatg acatatcttt tgcattgttt ttcgcatact tatctaagaa
    26041 atcttccaca aatccttcaa catctttcgc ttccgacgca tcaaccgttt cgtataatgt
    26101 gtcatcataa gtaatcattc gttgtttttc tgtattcttt ggtagtgccg taaaataagg
    26161 ataagcaata atacgacagc ccttgtttga aatagaaaag ggaagattga gtacttgtgt
    26221 gattgtcaca cttgtttctt tcttactctc tggattcatc gagcgaatat cataagttac
    26281 tttataacta gcagttggaa tggtttcaat ttcttttaat ccaataaacg aagcagcagt
    26341 taattttcga acacctgaaa cacttcctgg ttcttgaata aagttttgtg cataaaactc
    26401 tttttttaat gtttcttgac gttgttgttc ttgttcatga ttatcgaatg tattcatata
    26461 caaagcaaca aaacgattca taaaggattc aatttcaggt gtgtacgtta attctgaccg
    26521 actttgtact tctttctttt gtaattgttg gatttcatct ttcaaaaacg acacttgaac
    26581 cttcgttttc atggattgaa aaaatgccaa gccccctgaa aaacaaagaa ataaaaccaa
    26641 acaccaaatc catttcactg ctttttttga atggattttc ttttgcttcg gtactttctc
    26701 tgtataaact ttttctttcc gccgtagttg tcgttttttc ataagctact ccttctagta
    26761 tgtttttact agtacgtacg attgacaacg ataagcttgt ttttctgaaa aatagtccat
    26821 tcaattaccc tcattttcta ttccttttct ctttctttta tatccaacaa atccagcaat
    26881 acttgtcaac actcctccta gaacagaaag tgcaacatgt atttcttcac cagtctttgg
    26941 taagactttt gtttttccat ctgctgtttt gatttcaata ttgccacttg gaagtttctt
    27001 tacaggaatc gacaaatcct ttaccaaatt cccttcacta tcttggatta atggaatacc
    27061 atcttttaca ccaacaattg tttgatcacc tgctactttt aatggggtgg ttggtgttgg
    27121 aatatgggtc aattcctcta cattactagt gacaatcggt acactcattc cttgagaagt
    27181 attcgtcgta atttcaccgc ttggggttac cgatactgtg acttcttttg ctggaacaat
    27241 aggtttattt tcttttggaa ttgcttctga tttttcaaca ggttgtttcg gttcttcttt
    27301 ttgttcttca ctggtagacg acatcgttgg ctgttccgta cttgacgaat cagtattctt
    27361 ttcagaagaa ctggttgttc ctgattgttc cggagttgtg actatacttg aatccgttgt
    27421 tgttgaacta tgcacacctt cttcttcgat cgaatcagtc ggtaaagttg attcaggaaa
    27481 ctctggttct ggtgtcactg gctctttttc aggtttctct gactgcaatt gttcaggttc
    27541 tgctggtttt tccgttgttc ctccatttag ctctgtctca acatctggta atccttcccc
    27601 tggcaatgtt tctacaattt ctgacttagg tgtttctaca gtttcatctg cataaaccaa
    27661 tgaactccct aattgaaacg aaaataatga aattcctagt gttgttacga ctgctaatgt
    27721 tgtttttttc atgattattc ctccaatttt ttatgcaatt cgtgttttgt tcatagacgc
    27781 cgcactaata ttatctgaac gataaaagaa ctcccgtccg ttttcttcta acccaacata
    27841 tggattattt ttgaataatt gaatcaatag ttcactggtg ttgtattttg gatagtttgc
    27901 aaaaaaataa tactgtgctt gtcgcccatc cgaaaattca acaagtaatt cataacgata
    27961 ccgcttcaat ccttttcgtt gttttaaagg atctctatac caacttgtcc atcgttccat
    28021 tcgtggatag agatagacac gatacacata gaacaatgcc ataccacata ccaccaaaaa
    28081 taataatcgc cacataaaaa ttcccccttt tcttctacct ttcttgaatc atcgaacatt
    28141 cataccctct atagagattt gaaaaatcca tcatcaattg ttcatataaa cgttgttgca
    28201 aatagcgatt gtttcgaata cataattctt catagccatc aatcacttga tcttcttttt
    28261 catagcatct tgtagctcta tgacgctcag cttgcaagac ataaccaaac tctgcaccat
    28321 atcgttctac tgttaataac tgttgactac gcaataatgc aatataacaa tcacaaaaat
    28381 gttcaaccga catttgattt ttctcacgtt tgtgaaatag gtattcttta gaaagcacat
    28441 tattcgttaa acaatctgat aaatagcgat aatctggcgg tcggttattt tcatctgtga
    28501 atttttccca taataaactg atttttattc gttcagcggc tagatagtct tgttcgcgtg
    28561 gataaaattc atcaatcgca caaagttttt tatcacctga ataaacaaat ccatataatg
    28621 cgaaacgaac tcttcctttt caattggctc tcctaaaaat tccagtgaca taccatcttc
    28681 tccttcctaa aaaaaataaa aaagcagaaa ccgatttggc ttctactttt ctttcctttt
    28741 atagctcttt tttacggaag aatccgcaaa tgacattttt tcaaaaaatc aatcggcaca
    28801 agttcacgaa aacttggagc aattttggat agaatcactt ccccatcttg taaaatacaa
    28861 tcataaaaat catcagttac ttgatactta cgcttcttac aataattgat aaaatagtag
    28921 cgatcatttt ctatttccat tcgttgttct actaagcgca tacgaacatc atcatagaaa
    28981 taagccacaa atcgcccttc aagttcatgt ttttcaatgg gatactcttc tggtaacaat
    29041 ctattttttc gtcgtttata cattgctgga taccttagaa gaagttcatc taaacgtctg
    29101 tcagtatatg gtaactgacg aatcaacgat tctaatcgtt ctttatacag atagaataat
    29161 tggcgcaagc aatagtgtac cgcctctgga ttttctaata ctgttggatc acgtgaccaa
    29221 tacgcaccaa cataaatcat aatttttttc atttagacaa tcacaccagc aatactaatg
    29281 accgatccac aataggtaga acaagtggca tagcgaccaa tttcctctaa ttctatctca
    29341 atctcttcta aagaaagata tgtctgttct tctgttggct ggcgactcat ttcccaagtg
    29401 acagtcacca atgaaatttc ttccataaga ggtttttcgc tgctaagtgc tgccacacag
    29461 ttttcatata tcttcatttt atcgcagcct tttttaaccg ctaaaatcgc aggtattggc
    29521 aatgaaaatc gataaaagcg aatgaattct agccttcctt tccttcggct aaattccaac
    29581 tcttcgagtt cttgttcgta tcccttacga acttctaata agcgtgcaat ttcttgccag
    29641 ttctcttttt cctgataacg tccagctttt accgcttgtt caatataagg aactcgaaaa
    29701 cgaaaataag acaaatcaac catcttttca tttaatgctt cgattgcagc ctttaaatcc
    29761 aacaggcgca gccattctgt tgtcgtatat gcattcatgc aattttccct cctgacgttc
    29821 ccatccattc tagatagttt tgttgctcgt catttagttc ggcattatca atcccttctt
    29881 gtacaaagtc tcttcctaaa atacgatctg cttcttgtaa caactttaat gtcggagcta
    29941 cttgtttcaa aaaccagcgt tctgaacgat ctaatgagaa tttttctggc tttactgtaa
    30001 aatccaattc ttccatcgaa cgaaataatt ttgcccatcg tttatcaaca atccgtgcat
    30061 cactttccag tctatcccaa acaataagtt ttgcattaat taaaccaacg ccaatctctc
    30121 ctaaacgttt cggtgaatca cctaaaataa atgcttctac tgcttgtgtt gctttctcat
    30181 tggctaaccg taactcatat cgattataaa taccatattt cgttaatgct tctaattctg
    30241 aaattttttc tcggttcgca atttcaaaac gtttctcata aaaattaaaa aagagaggac
    30301 tctttcgcga tccaaaatac aaagataatc cttcacttcg aaaatagcca tcatctaaaa
    30361 aacaaccgcc aatattctgg aatctcttaa agtccatttc taataaacct gctttttgtt
    30421 tttctagtaa ttcaaagaga tcgaaatgtt cttccgtttc caatccccaa agttcatcta
    30481 acgcaatatc gaatcggcta cattgcacac gtgtataacc agcttccaac tttccttgat
    30541 ttttccaaat ggaatatagc catgttcgcc aatctgtttg ttgttcacgc atgacttcct
    30601 catattcccg gcaaccttgt cctgaaaatt gcacaagtac attttctgtt acagttcgtt
    30661 ttgaatgcca gaacacccag atattcccac gaacagaaag acagtcaaaa agatacaagc
    30721 ccgttggacg tgtttcaaat tctgtcagat ccattcgtaa tacacgttga atcactgttt
    30781 tgtagtctgt cccaaaaaag gaaagacgca aataatcaat cattgctcga agatctattc
    30841 cgcttttcat atacaatcga aagcgttcct tgattcgttg ttcaaaatcc tctgggattt
    30901 ttcttttccc ttgttccatc tttctaatgt aatcttttga gcagcccatc aattgcgcaa
    30961 atcttgcttg tgatagcggc tttttatctc cacttatatt atgaattgca cttaacttct
    31021 ttctgtagct ttttagctca atcggtgtca ttttctcgct ccttttataa aataacaaaa
    31081 tcgatttttt ttaacccttt agaaacaccg atatatcaac tagtccccct cgttttttgg
    31141 gaaaagtagt acaactgctg accttagata atcacttgat acaaaagggt ttataaaact
    31201 tttttctatg tgttatgtta tttctgcccc ccatattata tatcgggggg ctttacacaa
    31261 agaggccgtg cgcaagcgca cgacctcttt gtgagctgca cacgctgcta gcgagtgcgc
    31321 attataggcc catgcttcgc agccttaatg cgcaccgcca ggcagagtgc ggctaccaga
    31381 ctacgtctag agccctcccg atagataata actacaaaat taaatgatct aattttgtta
    31441 tttcactata tttttcagga gaaaaaacgc gataaattga caaagttaaa tcctcttcta
    31501 aatctactcg ataatgatac aatcgagtca atcgttctat atcttttttc gttagcaata
    31561 cttgattaat aacttttcct gtaaaaacac gttctttgcg caaaaagcgg taatcagtta
    31621 cttgttcaat acgattcaac caatcataaa acgttctgga agaaagagaa ggattaatca
    31681 ttcgtattgc tgtagctact ctataataac aactctctgc catttaactt cacctcctta
    31741 gttgattaca aaatatgcgc atcagaaaaa cttgttcctt ttggatcttt tgctaaatac
    31801 atttggcgct ctagttgttc ttgtaacaac tgattatcat ctcccatcgt ttgatcttga
    31861 ctatcctctt ttactgtaaa atcatagaca atcatttcag taaatttctc aaattctttg
    31921 ataaagtgat aatctttgta aacaaatggc gcaaaaaact ctacaggtac atcaaatcct
    31981 ggaaaagcat atccacgacc aggttgatct ttgttgtaaa atggcttatt tttaaaatct
    32041 tctccaaaag tcattaaata accaatggga gacaatcgac caacagaaat acggaatgtt
    32101 aaattatccc gaacaccact tggaaaatat tctgcatctg gtcgttgcat tgctaaaata
    32161 atgtacatcc ctgcttgacg accctttaat actaatggct gaatcaattt atcgactcta
    32221 tttctcgctt ccatatccaa cgaaccataa aaagctgccc attcatcaaa aaagataaaa
    32281 tgcggtggta acccataata agcataattt ttccctggtt catatttagg atctttcatg
    32341 gttttcatat aggcataccg ttgattcatt tcttttaatg catttcgtaa acaaataatc
    32401 atttcttcat ttattttgta aaacacatgt cctttgaata catcgacgtc acctaatgct
    32461 gctaaatctg ccgcttttcc atcgcaaata tctactgtcc caacacttaa acaagcttga
    32521 attaaagaat acaataaata ggttttccca ccaccgattg caccagcaat caacatattt
    32581 ggtgattgat catataccca atccaaagtt ttcattaaat gaatacgtcc attttctgct
    32641 atacattgat caataggaat ccgaccagaa tctgaaagga atacataatt gattcgggct
    32701 ttttctcgtt cttcacgaat taaatcacgc aaaaatactt cagataacaa atgacccatt
    32761 tttaaaaatc gttcgtgaaa acgcccacca tctaaaggaa aagaaaccac taattcttgt
    32821 ttcttttgat aaaaataaac ttttggtaat ctcatttttt cccttgtttg tttctcacta
    32881 acttgtttct ttgtataaac aaaccgattg tcaattaaca ttcgaacaag taactgacgc
    32941 caataaacag aggcaaaata tccttctttt agtcgcgacc aatgcatcaa ccctaaaatt
    33001 aacccactaa ccagcaacaa atacaacaca atacttattc caggaataag atacatttgc
    33061 caattcgaaa acgtacttaa acgtggataa aatactttcc aactaaacca acctaacaga
    33121 atcaaaaatg gaaacaaaaa gaaaccataa tagcaaaacc ataaataacg attgaaatag
    33181 cgaattcgcc gaccacgata cttgaaaaaa tgagctttca attgtcacat tcctcctttc
    33241 tgtttttact tttcctgtgc taaaaacttt tgacaaaaag caactaatac aggaatatca
    33301 catttagtaa aaaaacataa tcgaaaaaga tttaatcgat ttttataagg gtgtgcacac
    33361 atattacata ttcgtactat acgaatccaa atcacttcct gatgatcttg tttccactgg
    33421 tacggtaatg aaaaacgaac aagatcacgt aaaaacatac actgcccaat aaccgcacaa
    33481 atatatgcat ttgtttgtac aaaaatcgtt ggattgtctc caaaatactc aatcaattgt
    33541 tggatatttt gataacaagc acaatctctc aaagtatttg attggtttta tctgaattca
    33601 aaatctcccc ttccttctat cttagataaa aagaatagga agactccttc ctattctttc
    33661 aaaaaaacct tattttttct ctttttcctt agaatcaaca cttggttgtt tttgatctaa
    33721 acctttttct tgtgattgtt tcatattagg attatttgtt ggagcttcta ctttctctaa
    33781 tcctttcgca taaatcacta aatctgaata ttcacgattg ccatcttgtg ctggaatata
    33841 taccacatga tattctggat caattaattt cacaggatca cgtcgtttaa aaccagtcaa
    33901 atctacatct gctggaaatt taactcgtcg tgcaatcttt ggttcatctg gatttccaaa
    33961 aactaattgt gctcgctgtg atcgaatttc tcccgtataa tcgcctgttt cattatcaaa
    34021 tacacgatca gactcttcta atgcgccaaa gcgtacggct cctaaacaag tttcatctaa
    34081 tgcttctgta atgtcataat tatttggaaa ttttaatccc atcttacaaa acctccccaa
    34141 tttttacacc agttaaaaag acaccaacat cttgatagcc agttgttcga cgctctgttt
    34201 gtcccatatc atttgtttca cgactattca ctcgttcttt acgaaaaaca aaataagctt
    34261 cttcaaatga aatacgcacc tctttttctg gtaatcgtaa tcttttatcc tcttcagctg
    34321 tgagataaac aaaaaaagca ggctgttctt ctcgcgaaca ctctgcttgt aattgaacat
    34381 atcgcccaga cacaccatta atttcctttg gtggattagg ttcccgtgaa cccaataaaa
    34441 atacttgacc taaaaactct ttcttcatac gcaatgcttt ttctgccata aagtttttcc
    34501 tcctcttaaa aaccaaaata aattctaaat atttctacat tacaatcaaa caagcggtta
    34561 aaaatcctaa ccgcttgttc ctcatgacta atctttggct ttacgtactt tataaagtgt
    34621 tatacctaaa gcaatgacta atactactaa tccaagaacc ataagtatac tacttgtttg
    34681 ttcacctgtt tttggcaaca ttggtacaac agtagctggt ttaacccgtt gttctggttt
    34741 cactggttgc ggtggttttg gcgcttccac aatttgaacc gtttgatctt tgtttgttag
    34801 atctacattg tgtttcgcca cttcttcaaa cgtttctttc tcatcttccg ttttcgcttg
    34861 gagccattcc gcaaaactca agccttttcc tgcaagattg cgaccgtcca ctaagaattc
    34921 aaataagaat tccatcattt ctttatcggc cgcaaagact ttttccgcat gagtgccttc
    34981 aaatggtgtg ccgtctggtg ttaagtagcc ttgaacaatt aagcgataga tttgaccaat
    35041 cgcaagaccg tctactttga cccattcaag cacagtttga tttggcaagg ccaagatctc
    35101 ttttccgcca tttttattcg tcgctttcgt cgtaatggtt ggattactga ttttgatggt
    35161 ttggtcattg tcggtaatat ctgcgtgaga agccaataat acgccttctc taaacagatc
    35221 ttcaaagacc acgacttctt tgcctcgcaa cgcacgtgcg tctagaataa agtctagatt
    35281 gactgtacca tccgttgttt ctgccacaaa cgttaaggta cttgtgactt cttttccatc
    35341 tactagcact ggtttttccg ttactttgtc cattagaaca ccgttgactg tgtatgtttt
    35401 tccaacgacc aaatcgtggt atttcacagc gtctgtaatg gtgactttcg ttaatggatt
    35461 aacctctttc aagccagtgg gtttatgtgt agccgttgta cgtacacttg ggttagttac
    35521 tcgtaccgtt tgccctttgt cgttgatgtc tttatggttt gctagttctt catcatttct
    35581 aaaaagactt tcaaacacga cgatttcacg accatttata cctgtcaaat caaaggtaaa
    35641 tggtacgatc accgtttcat tttctgcttt ggcaataaag ccaacactcg tttctaccgt
    35701 atttccatgc acaagcaagg gttcaccggt tgctttatcc attaagatcc ctttgaccaa
    35761 gtatgctttt cctggaagaa tctcggtaat ttcaacggta tcgtttaagg taaacaatcc
    35821 tgttgggtct gcgactgtca atccgtcttc aaagacagcc gtggtatgaa cggttggatt
    35881 attcactttc acactttggg cttcatcgtt gatatccgca tgtgctgcaa cttcaatgcc
    35941 atcacggaaa agtttttcaa aaacaacgat cgtttgacct ttcagaacac tagcattaac
    36001 cacaaattca aggtcttttg tgccattgac tttgtctgca ataaaggcca aggtacttgt
    36061 gatttctttg ccatcttgta aaattggcgc attcgttgcc ttgttcatca atactcctga
    36121 aatggtgtat tcttttccga caaacaagtt ggtataagaa acactgtctt taatgacgat
    36181 cgtttctaat ggatcaacca ctttttcacc atcggcttta tttgacgctt gtgtttctag
    36241 ttttggtgga atcaagtaat tacgtacaga aaccactaac gtttccccat catctggcgc
    36301 attttgtttg aatgcaaccg tgaatgcttg tttatctgta tttggttgga aactttctaa
    36361 tggggcattt tccaagaagt aatagtcatc ggcaactaga cctttcacta aaatttcccc
    36421 gttttgatca gtggtatatt caccaattgc ttgattttta ccgttataca aggtaaagtt
    36481 cacacctgcg agcggcgttt tcttcttgtt ccattcttca tacttgaata attttacact
    36541 tttccgtgct tgacggttcg caaaatggat cactttgatc ggttctgtat cattggtaat
    36601 cgagaacact aatgggtttt gattcaaaac gtaatttacg ggggctttga tttcttccaa
    36661 acgatagcga tcttttccat aagtaagtgt accgttagtt aggaaaaagc ctttttcatt
    36721 ggttttaaag atatccgttg tttctgtatc atttggaatc tccattgtga cataacgatt
    36781 ggctaaagta tcaaaaatct tgaattctgt attagcaagt ggaatcactt ttcctgtttc
    36841 ttgatccact ttcaccactt taagacgttg ttcaattact ttatcttcta aaacataatg
    36901 gaaagtttgc ccattttcag aaattgtgac ttcaagtggt tcaaatagtt tatacccttc
    36961 ttttcctttg gtttcagaaa gaatgtacgt atcaaagaca acggtatttt taccaaaagt
    37021 agcataacca tcattgtctg tcacaacggt tttcaccact ttgccagttg tttttgacgt
    37081 caaagtgatt tcaatgccag ctaattttgg tttgttatct ggattcgttg aatcgactaa
    37141 atctttatta gcaactttca ctaaatcaat ggttcctttg atcacttgat cttttgcggt
    37201 cgcattgaca gtttttccag gttcaacaac aatttcaatt gcttcatcag aaagcacata
    37261 accttttggc gctttgattt cttttaaaac atatttgcca ggatcaagat ctttaatttc
    37321 tgcctgtact ttgccgttaa tttttttcaa ggtaatttct ttaatctttt tcccatctgc
    37381 ttgatacaaa ccatagaccg cattttctaa agaagctgca ccttgtgctt tcacaccagt
    37441 ttccgcatct tctttaaaca cacgaatgtt tccttgtttt agaatttgta aattaataac
    37501 agacgcatta ggttctgttg gatgtaacac accaattgtt tgagctcctg gacgacgata
    37561 ggctaatggc gcaccttgaa ctttaatttt attcaattga atttttgctt tatccggtgc
    37621 ctcttttgtg actgtaatcc atacttcatt gccgtgaata gatacattga caccttttgg
    37681 tttttgaatg tctttcacat atttcaaaaa atcattttta ttctttactt tcaacgtttc
    37741 gccaattttt accgtatgtg tttgattatt aaaagttgct ttttcaccaa agttattaat
    37801 caaacgttga atttctgctt ttcgacgatc ataatcaaca cggatatttt tgattgggat
    37861 ttttgtgccc aaagcttccc aaatcataaa ttgtgccgca atgtattgtt catcggattt
    37921 gtctttattt gtgacatatc ctaaataaga gatcaagctt gtttttttcc gtacatttga
    37981 atttttcaaa tagtttttca aagcagtagc tgtataaact tgaccttctg cggctgagac
    38041 accaggctca atacaaaacg ccacttgtcc attaatctca aaacgaacca tataatttaa
    38101 agtgaagttt agattgttcg gactagaagt aacaccaata ttttcgcccc aatcaatttt
    38161 ccgaccacct aaaacagctg cattggttgc acggcgaaca cgaaccgaac gattggttgg
    38221 tactgttact aacagtgtag gtgtacctgt ttttggaatg ttctgctctt ttttcttttg
    38281 attttcaata ctagccgtag attctttgtt tggtttcgtt ggttgatttt gactagctgc
    38341 ggttgaagag attgtttttt caacgttttc ctcatttttt ccttctttgt cagcagtagc
    38401 cgctggttgt tccactgttt cttctattcg tttcttttct tccgcttgtt tctcagaaga
    38461 ctctggctgc acagaaggcg ttgcttcggc agctttttct ccttctagag tggacgtttc
    38521 tgaagcaggg gttgtaattg aggcagtttc ttcaactggt tgtgaagtac caggactatt
    38581 ccctgggtgt tgtgtttccc caatcgtctg atcgagagtc gttttggaat tgaccgttgg
    38641 cgcttctgtc acaggggcct gttcaacagt ggcttcacca gctgggaccc cggcttctgc
    38701 tggttggact tctgtcactt cagaagcgac ttgggcaatg gcttccatcg taggttgtat
    38761 agccgtcgtt tcttctgcat gtgcttgagc agttcccacc aagaaacaga attgagaaaa
    38821 agccaccaat gcgagtgctt tcaaccaatt cattttcgtt tttgcataca caagaattcc
    38881 tccttttcct gagaatttta tataataaaa caaaacgccg ttaccaaaag tgataacgac
    38941 gtgaactgtc tcttctattt ttatctggcg ctcttatctg aacacatttc atcaatgatt
    39001 ttaccctccc actataatta cagaacaaaa aaagaacctg cttcgtggaa atcaactgtc
    39061 catttcccaa ttggaatacc agcttttttg gcaacttcac catcaccaaa tctcatgcca
    39121 taccaattac taccttcatc cttaatttct ttccaaccat atgacatagc ttcatctaat
    39181 gaatcaaaaa tcatgacact attgccaatt gttacaggat ctggcttaag atcttctgga
    39241 agagaaatat caatcatacc ataatgatcc gattcctcag tattattgtc attactagct
    39301 actggtttgg ttgttctact ggcttatttt gatacaacaa gtactcttat tcttctttta
    39361 cttctccgtt ttcaatttcc cattcaaacc actccgcaaa gtcttgctta aaaccatcta
    39421 ctcgatacct attttgtaaa taggcatctt ctgacgtcgt aggatctaaa taggtaggtt
    39481 tattctctgg acgagcatag acacctaccc atgtttcgta atctccttca aaataactat
    39541 ctaccaaata gccttttttt ctaagaatct cccgaacttg atttttaatt attgatactt
    39601 gttcaaaacc atcactcatt ctatcacctc aaataactct agattctcat aaatattccc
    39661 gacaatttca atcctatcaa tgatctctaa caaatcgcta cttatgcttc cccattcgta
    39721 taagaatttc ccttccgcaa aataaatttt ccataaactt cttcatgatc gtcccaacca
    39781 atatcactct cgaaaaattc cacgttgttc ttatctttta gctcagtaaa tgccataagt
    39841 tcaacatgtt ttccaacctc gaaacaatca caccacccat caaccgttac acgtgtgcct
    39901 tcaataccta agaaactttg tcctcgtgta ttaaacacta aaactttccg cattttttgc
    39961 tcattaatta atcacgcgcg aaatctagga atcacaactt attcgcttct tctttataaa
    40021 taaaaaaact ccaataatcg gaaattacta tcttttcctc attccttttt taaatcttca
    40081 tacttcttct tatctttgtc ctaacctaat aacacaaatt ttgaagaaaa actcagtaaa
    40141 acctgattct ttttttatct tcacaacaac caactttttc ttcagatcct tttactagaa
    40201 cttgtataca aaaattgttg aatgctgata taatttgcgg ctacttgaaa aaacgataga
    40261 tgtaaaaaga taaatagaat cattttttat tctatatcag tctatgattc attgcttatc
    40321 aatcacccaa cccattcgat gccgtttttt ttagagaaat ttaaaaaaga ccgtacgaat
    40381 ctcgcattat ccgattactt ttccagaaaa gatccccaat tctgtataaa taaccctatc
    40441 ttcttgttgg tttcattttc tcatataaga attcagtcaa tctacccact atgaccatta
    40501 ctacgtccaa cacaactgac atattaacca cgtaagtatt ccctcacaga tctccgaatc
    40561 tccatggtat ggattcccat cctgacgctg cagaggacaa catatttcat gtggctctgt
    40621 acccttttga tttggaaaca ctacaaatca atactcatct ataacttatc aagcgaactt
    40681 tcgctaggct tctagtgatt actaaattgt tggataacat acatagccca ttttatctag
    40741 ctgttattca taacagttag ttcttgtatt acttcttccg cttgtgttgc cattgagctt
    40801 gtcaaaaagt tacttagaaa aaagctgcca gtaaagcaac tttcaacaaa ccctttttgt
    40861 ttcttatcat atcaagaaac ctccttttat aaattttttc tataataaaa aacgtcgata
    40921 acttaataag tatcgacgta aactattttt atatcccgta aatcaaaaat tctaaagaaa
    40981 gatttcctat ataagcatat tggataattc gattagtatt gggtatatct ctaccattct
    41041 catacctatc tatggaccat tttgaaattg aaggagaaaa aagctttcca aactcctccc
    41101 tttctagata ataatctttc ctaattttcc tcatccttaa tcccatacta aaagaattta
    41161 tctttttaaa atcgctaact ctttcatctt ttggaagtat attcttataa tcttctccgt
    41221 acataaggta aggaacagtg accttaccaa gataggcaat attcattagt ttttcaatat
    41281 ctggaatatt aatacctttt tcccatctac ttataacatt tttgcctgta tagatggtaa
    41341 agtttttacc aaatttttca agcgtctctt cccggttctt tcggacttct cgtattcttt
    41401 ttcccataac aattttatcg tcttttgata aactaaatat ctcactatca cgattaatct
    41461 ccttcaaaat ttctttttca ttacttaata gaaaaatatc gatttttttt gcatttcttt
    41521 tgacggattt ctctttctat ttaacacata actgagtaat acttcactaa ttcctatatt
    41581 atcagctaac tctttgttaa gtaacttatt catatctctg tatgcaatta gtttaccgat
    41641 gagaatctca atcttatctt cctcatcttt tattagagtt tctatattca gaatcttgct
    41701 tagagtatta tctacgtctt tagggatttt tcttgaccct ttttcatatt taactaaagt
    41761 actttgtgaa atacctgcta aatcagctaa ctttttttga gatagttttt tctcttttct
    41821 tagagattta agaacccttc cacttgaatt atcaaccatg aaaaaagcac ctcctatgag
    41881 atgctttcat catatactga cagctaaaaa tcttcaagaa aaatattcca attttgttaa
    41941 ttttagtatc gccgtgataa ccaaatgaca gtttaaaatc ttttatacag ataatcctca
    42001 gtgttgcatc tactcaaaaa ggtttattta ataggttttt cgattgatta taagttattt
    42061 cacactatct tgctcatcca ttttcagaac ggccatgaag gcttcttgcg gaacttcgac
    42121 ggagccgatt tgtttcatcc gcttcttccc ttctttttgt ttctctaaga gtttacgttt
    42181 acgagaaaca tctccaccat aacatttagc caagacgttt ttacgcaagg ctttgatgtc
    42241 tgaacgggca acgatttttt gtccaatagc tgcttggatt ggcacctcaa attgttggcg
    42301 tgggattagt tttttcagtt tttcaacgat tgcttttcca cgttcatagg caaagtctcg
    42361 gtgaacgata aagcttaatg catcgacttt ttctccattc agcaagatgt ccatcttcac
    42421 taacttgctt ttttgataac cagacatttc ataatccaat gaggcatagc ctttcgtgct
    42481 tgatttcaat ttgtcgaaaa agtcaaagac aatttcagaa agcggaatat tatagacgac
    42541 atttactcgg taatcatcta aataatccat cgtaatgaat tctccccgtt ttcgttgaga
    42601 aagttccatt actgcaccga caaaatcatt tgggaccatg atctgtgctt tgacgaatgg
    42661 ttcttctaca tcctgaatcg ttacaggttc aggaaaatct gccgggttat ctactgtagc
    42721 agtcgtacca tccgttttat taacatggta aataacggat ggtgcagtcg tgatcaattc
    42781 tagattgaat tcccgttcca agcgttcttg gacgacatcc atatgaagaa gtccgaggaa
    42841 tccacagcgg aacccaaaac ctaatgcttg agaggtttct ggttcgaatt gtaaagcagc
    42901 atcattcaat tgcagttttt ctaaagcttc ccgcaaatcg ttgtaacgag aagtatcaat
    42961 tggataaaga ccacaataaa ccatcggatt catttttcgg taacctggta aagcttcagc
    43021 ggcaggattg tctgctaacg ttactgtatc ccctactcgt gtatcttgga cagttttgat
    43081 acttgctgtg atataaccga catcaccgac catcaaaaag tctctagcaa ctgcttttgg
    43141 cgagaagacc ccgacctctg taacatcaaa tgttttgcca ttactcatca gtttgatttt
    43201 gtctccgggt ttgaccatac cgtccgtgat ccggacattt agaacaacac cgcggtaact
    43261 atcataaata gagtcaaaga tcaaagcttt tagcggtgca tctaagtctc cacttggtgc
    43321 aggaacatat tccacgatct gctcgagaat atcttcaatc ccaatccctg atttggcact
    43381 ggctaataca gcttcactag catcgattcc gattacgtct tcgatttctt gacggacacg
    43441 ttcgggatct gctgcgggta ggtcgatttt attgatgact ggcaggatct ccaaatcatt
    43501 gtctaacgct aaataaacat tggccaatgt ttgtgcttcg attccttgtg ctgcatcgac
    43561 cactaaaacg gcaccctcac aggcagcaag gcttcgagag acttcatagg tgaagtcgac
    43621 gtgccctggg gtgtcaatca agtgaaagat atatgtttct ccatttttcg ctgtgtaatt
    43681 gagttctaca gcatttaatt taatcgtgat tccacgttca cgttccaaat ccatcgagtc
    43741 taacagctga tcttgcattt cgcgagacgt cacagtgtgc gtcatttcta aaatacgatc
    43801 ggccaatgta gatttcccat ggtcgatatg agcgatgatc gaaaaattac gaatctgctc
    43861 ttggcgttct ttcattttct ttatatccat agcgtctcct cttttcatat aatcagcact
    43921 ttccattata ccaacgaaaa gcagtaattt aaagagtttt taattagtca gctatagaag
    43981 ttttttttgt agaattttgc tatactgtta tcaagctaat aaatggagat gaaaaaatgg
    44041 atcaaaaaga ttttagagaa aatcttgaat taaaaccggt cactcaagaa catatcgatc
    44101 aattcaatga attgctttcc tatgtgttcc aagtgactga agcagacatc gaggaaagcg
    44161 ggtttgagaa taaacgagct tttatccgtt ccaaaaaacc gattttggaa gtatcgaaag
    44221 tgttcggatg gttccacgaa aataaactga tctctcaaat cgctatctat ccttgtgaag
    44281 tcaatattca cggtgcacgt tataaaatgg gtggtgtgac tggagttgga acttatccag
    44341 aatatgctaa ccatggattg atgcaagatc taattatcgt tgcattggat aatatgcgca
    44401 agaataagca atggatctct tatttgtatc cttacagtat cccctactat cggcgtaaag
    44461 gatgggaaat catgtctgat aaactttcct ttaaaatcag agatacacag ctacctaaac
    44521 aaatcccagt aagtggtatg gttgagcgat taccagttga tcatccagac gtattttccg
    44581 tttatgacaa atttgcccaa caaaaccatg gtgctttatt ccgcagtgat tttcattggg
    44641 aagagtattg gcgtttcgaa aatgaagatg agcgcacagc cgctgtctac tacgatagca
    44701 accatgaacc aagaggtgtt ctgttctact gggtagctga agaaatattt cacgtaaaag
    44761 aaatgttcta tcttgatcaa gaagctcgaa atggcttatg gaactttatt tccgcacatt
    44821 tttccatgat ctactgggta catggagata tttataaaaa tgagccttta gcatttttga
    44881 ttgaagatag tcagatcaaa gagcagatcg aaccatattt tatggctcgg atcgttgatg
    44941 taaaagaatt ccttcaacgg tttccgtttg ttggaacagc tgatgctttt catttcatca
    45001 ttgaagatcc tgtcgctcct tggaataatg gtgtcttcgc tttaacatgg gatgaacagg
    45061 gacaagtccg tgtcttaaat gaacctatag gaaaatccgt tcgactggat atccaaacat
    45121 tgacttgctt gatgatgaat tatcgccgtg cttcttattt ggcaagaatc gaacggttag
    45181 aaacagatga agaaacactg aagtcactag agcgtatcat tccaaacatg gaagcttact
    45241 ttagcgatta tttttgataa aaaggatgat gtttagatga aaatttattt tgccgcacca
    45301 atgtttgcta aaagtgattt gttatataac caacagttag ttaaagaaat cagagagctc
    45361 tcttctgagc tttcgatcta tcttcctcaa gaaaatgaag caatcaatga caaaactgct
    45421 tatgcagaca gtcgaatgat tgctcttgct gacacagaaa aagtgttggc tagtgattta
    45481 atgattgctt tactagatgg gctgacgatc gatgccgggg tagcatcgga aatcggtgtg
    45541 gcttatgcga aaggcatccc agtgatcggc ttatatactg atactcgaca gcaaggcgga
    45601 acccacccga aaaaaatcgc tgcactacaa gaaacagctg aaaatcaatt tcactacctg
    45661 aacttatata caataggttt gatcaaattg aacggaaaag tggtttcttc agaaattgag
    45721 ttgctttcag aagtaaaaag atttttagat ggagggactt tcagtgatta aagaaatcaa
    45781 aaaggtgcaa atagctttac ttgcttttgg tgtattcgtt gtctgctata atttttatga
    45841 atttatcaca caaaaatatt cgacttctca aggaatcaca tttatcgtgg aatctttatt
    45901 agggattgca ttgattttca tgccacaagt cattttgaaa gttttcaaac ttaaaatacc
    45961 agcagcaatc gttttgtttt actggttttt cttgttcatc tctgtctttt taggcacagg
    46021 gatgcatttg atcagtatca tctctttttg ggacaaaatc ttacatgcgg tgagtccaat
    46081 ggtcctgaca gctcttggct atggattgat tggttacttg atgaaagatg ctgagatatc
    46141 aaaaaccagt ccttggttgt tcctcttatt cggctttgcg tttgctggac tttgcggcgt
    46201 gttttgggag ttctgggaat tcttatgcga ccagttctta ggcatgaatc ttcaacgttt
    46261 tgctgcttct gatggcacac tgtttgtcgg acgagcagca ttgatggata cgatgggcga
    46321 cttgctgaca aatacgatag gtgctgcctt aatgggattg tttgcatggt ctcaaagtaa
    46381 aaaagatgag cgttactttg aaagttataa attagaaaaa gtgaaaaata cctaataaaa
    46441 gaggttgtga cagaagcggg cagcttcaag aaatttcggc ttatttttcg aagaaactac
    46501 ttctggaaca ctgtttattt gaaaaaagga ggtctgacac tagttgtgtc agaccccttt
    46561 tttcttttat agtctcaatg gaagattaga cgatttcttc tagctcttct gttttgaaat
    46621 gaagttgtcc atcaagtaaa gtaatcgtta cttttgattt aggcataaca tgtcctgcaa
    46681 cgatttcttt agctagtggt gtttctactt ccttagtgat aaatcgtttc aatggtcttg
    46741 caccatatgc tggttcataa gcattttcag caatccacgt tttggcttca tcactgattg
    46801 tcagcaggat ttcttgatgt tccagacgtt gtgccaattg cgccaccatt ttgtcaacga
    46861 ttcctttcac gttgtctagg ctcaatggtg taaataaaat cgtgtcgtcg attcggttca
    46921 agaattctgg tttgaagttt ccacgtaata gcgtgttgac ttgttcagcc actgcttctg
    46981 gaatcgttcc atcagcagtc acgccttcca gcagtaactg tgaaccgata ttgctggtca
    47041 tgatcagaac cgtatttttg aaatctacta ctcgcccttt tgaatcagtc aagcgtccgt
    47101 catctaggac ttgtaacaag atattgaaga catcgggatg cgctttttcg atttcatcca
    47161 acaagacgat tgtataagga tttcgtctga cagcttccgt taattgacca ccttcttcgt
    47221 aacctacata gcctggagga gctccgacta gacgagacac agcatgtttt tccatatatt
    47281 cactcatatc gatccgtacc atatgatctt ctgagtcaaa caagttctca gctaacgctt
    47341 tcgctaattc ggtttttccg acaccagttg gtcctaggaa aaggaaagaa cctagaggac
    47401 gatttgggtc ttgcaatcca gcccgtgaac gaattaccgc gtcactgacc gcatcaactg
    47461 cttcatcttg accaatcact cgtttatgaa gtgtttcatt caatttaatt agtttttctc
    47521 gttcaccttc tacaagtttc gttacgggga tacccgttaa tctgccaacg acttgagcaa
    47581 tctcattttc ggtaacggac tcttgaacca tcttaatctc gctgtctttt gctttagctt
    47641 ctaattcctt caattctttt tctaattgag gtatcgtacc atgacgcaat acagcagcgc
    47701 gttctaaatc atagttattt tctgcatctt ctaattcgtg ttttgcttta tcgatttcag
    47761 cacgttttgc tgaaacagaa ttgacttctt ctttttctgt ttcccactgc atcttcatcg
    47821 catttgcttc ttcacgaagt tcagctaatt cttcttgcaa atttttcaag cgttttttac
    47881 ttgcatcatc tgattctttt ttcagtgcag cttcttcgat ttccaactgc atcaaacgtc
    47941 tagtaacttg atctaattcc gttggcatag agttcatttc tacccgaatc gttgcactgg
    48001 cttcatcgat caaatcgatt gctttgtccg gtaagaaccg atcagtaata taacggtcag
    48061 ataaagtagc tgctgctact aatgcgttgt catggatgtt aacaccatgg tggatctcaa
    48121 aacgttcttt taatccacgc agaatactga tcgtatcttc cactgttggt tctttgacta
    48181 ataccttttg aaagcgacgt tccaacgctt tgtctttttc catatattga cggtactcat
    48241 ctaaagttgt ggcaccgatc aaatgtaatt caccgcgagc aagcattggt ttcaacagat
    48301 ttccggcatc catacttcct tctgtttttc ctgcccctac gatattgtgg atttcatcga
    48361 tgaacaagag gatacgtcca tcactttttt tgacttcttt caagactgct tttagtcttt
    48421 cttcaaattc accacggaat tttgctccag cgatcaatgc acccatatct aatgaaaaaa
    48481 tcgttttatc ttttaaattt tcaggcacat ctttgcgtac gatacgttga gcaagccctt
    48541 caacgattgc cgttttccct acaccgggtt ctcctatcag aacaggatta ttttttgttt
    48601 ttcgtgaaag aatacggatg acatcacgga tttcttcatc acgaccgatg attggatcca
    48661 tttttccgct tttgacttgc tgtactaaat caacgccgta tttttctaat gctttgtatt
    48721 gttcttcttg gttttgtgag gtcactcttt ctcctcctct catctcttcg atgtttttac
    48781 gcaattcttt ttcagataat ccgtttttat tcaaataaac agttaacgga taatttttta
    48841 atttcatcaa cgctaaaata acgacttccg ttgaaagaaa ctcgtcgccg aagctttcac
    48901 gtatttggtc tgcttcattc aataatcgaa agaaattctg gctgaggttt tgtccatatt
    48961 ggacgtttcc accagaaaca actggatact catccagtag acgatcaatt tcatgttcaa
    49021 aagattcgac atccaatccg gcatccgtat agaaatttcg accaaaatga ttagattgta
    49081 aaaagatttt ccatacatgg gcaatgtcga tatcttgatg ttttcgagtg accgcaatct
    49141 gttgagcttc agcaatcgct tcttgaagcg tcgtagtcat tttctcaata ttcatacagg
    49201 tataccctcc taattaaagg taagatcact tatttctttg atctttacaa aaactattat
    49261 atcgctttgg tcaattttgg tcaaaatata cacatagtt
//
LOCUS       DAZUJR010000009        48111 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.009, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000009 DAZUJR010000000
VERSION     DAZUJR010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 48111)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48111)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48111
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.009"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            95..268
                     /locus_tag="ACG804_000499"
     CDS             95..268
                     /locus_tag="ACG804_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831454.1"
                     /translation="MLPEKNGGLDFSKPPPAKYKMGVGKVCPTAVFFFSAAGQIEYYN
                     LQCITKDALTTFQ"
     gene            complement(334..942)
                     /locus_tag="ACG804_000500"
     CDS             complement(334..942)
                     /locus_tag="ACG804_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HFS4831455.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
     gene            complement(948..1976)
                     /gene="vanB"
                     /locus_tag="ACG804_000501"
     CDS             complement(948..1976)
                     /gene="vanB"
                     /locus_tag="ACG804_000501"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HFS4831456.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKSAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGTFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDS
                     LITLALKR"
     gene            complement(1969..2940)
                     /locus_tag="ACG804_000502"
     CDS             complement(1969..2940)
                     /locus_tag="ACG804_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HFS4831457.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVGHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            complement(2937..3764)
                     /gene="vanW-B"
                     /locus_tag="ACG804_000503"
     CDS             complement(2937..3764)
                     /gene="vanW-B"
                     /locus_tag="ACG804_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance accessory protein
                     VanW-B"
                     /protein_id="HFS4831458.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGEKS
                     LSHLLFETDCALYNHNTGFDMIYQENKVFNLKLAAKTLNGLLIRPGEPFSFWWLVRHA
                     DKDTPYKDGLTVTNGKLTTMSGGGMCQMSNLLFWMFLHTPLTIIQRRGHEVKEFPEPN
                     SDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKIIGQVSADKEPQALYKITNG
                     SIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKCKICYPLPESVDIQEENQ"
     gene            complement(3782..4588)
                     /gene="vanY"
                     /locus_tag="ACG804_000504"
     CDS             complement(3782..4588)
                     /gene="vanY"
                     /locus_tag="ACG804_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-B/VanY-G family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HFS4831459.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGRR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            complement(4759..6102)
                     /gene="vanS-B"
                     /locus_tag="ACG804_000505"
     CDS             complement(4759..6102)
                     /gene="vanS-B"
                     /locus_tag="ACG804_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-B"
                     /protein_id="HFS4831460.1"
                     /translation="MERKGIFIKVFSYTIIALLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPDFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQAQSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLTSTL"
     gene            complement(6105..6764)
                     /gene="vanR-B"
                     /locus_tag="ACG804_000506"
     CDS             complement(6105..6764)
                     /gene="vanR-B"
                     /locus_tag="ACG804_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-B"
                     /protein_id="HFS4831461.1"
                     /translation="MSIRILLVEDDDHICNTVRAFLAEAGYQVDACTDGNEAYTKFYE
                     NTYQLVILDIMLPGMNGHELLREFRAKNDTPILMMTALSDDENQIRAFDAEADDYVTK
                     PFKMQILLKRVEALLRRSGALAKEIRVGRLTLLPEDFTVLCDGTELPLTRKEFEILLL
                     LVQNKGRTLTHEIILSRIWGYDFEGDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEE
                     S"
     gene            complement(7382..7549)
                     /locus_tag="ACG804_000507"
     CDS             complement(7382..7549)
                     /locus_tag="ACG804_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831462.1"
                     /translation="MKKRNFIMTEMENARNKDEEAAAVSAVYGRIEKAGIWILYGEVS
                     RHWITAGLMRL"
     gene            complement(7707..7892)
                     /locus_tag="ACG804_000508"
     CDS             complement(7707..7892)
                     /locus_tag="ACG804_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HFS4831463.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            8037..8408
                     /locus_tag="ACG804_000509"
     CDS             8037..8408
                     /locus_tag="ACG804_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4831464.1"
                     /translation="MANIEDCPGFETFGADVKAARQAKRVSRKAMAEKINIDWRYLAN
                     IENDGAIPSLPVVIQLIKACGLPVERYFNPEIMREESELRQRVSHKLKLCPEEYLPII
                     EGAIDSAILIEKPKKNETEDV"
     gene            8666..8995
                     /gene="mobC"
                     /locus_tag="ACG804_000510"
     CDS             8666..8995
                     /gene="mobC"
                     /locus_tag="ACG804_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HFS4831465.1"
                     /translation="MANRKRKIVLRVPVTPEERAMIEQKMALLHTKNFSAYARKMLID
                     GYIVNMDTSDIRAQTAEIQKIGVNVNQIAKRLNGMGPVYAQDIEDIKGALAQIWQLQR
                     YILSSQR"
     gene            8956..10284
                     /locus_tag="ACG804_000511"
     CDS             8956..10284
                     /locus_tag="ACG804_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HFS4831466.1"
                     /translation="MAVTKIHPIKSTLKKALDYIENPDKTDGKLLVASFACSYETADI
                     EFEMLLAQAYQKGNNLGHHLIQSFAPGEATPEQAHEIGKQLAEEVLQGKYPYVLTTHI
                     DKGHVHNHIIFCAVDMVNQRKYISNKQSYAYIRRTSDRLCKENGLSVVKPGQSKGKSY
                     AEWDAQRKGTSWKAKLKAAIDAAIPQAKDFDDFLRLMQAQGYEIKPGKFISFRAPGQE
                     RFTRCKTLGEAYTEEAIKERIKGRVITRAPKERKGISLRIDLENNIKAQQSAGYERWA
                     KLHNLKQAAKTLNFLTEHGIDTYPDLESKVAEITAASDEAAATLKAMEHRLADMAVLI
                     KNISTYKQLWPVAMEYRNAADKAKFRREHESTLILYEAAAKALKGQGVKKLPDLYALK
                     AEYKRLAEEKERLYEKYGEAKKQMQEYGIIKQNVDGILRMTPGKEWTQEL"
     gene            10281..10652
                     /locus_tag="ACG804_000512"
     CDS             10281..10652
                     /locus_tag="ACG804_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HFS4831467.1"
                     /translation="MSIPRMNYPQYRKARKLTHECCNYCDGNCLLLDDGEECICVQSI
                     SYSLLCRWFKAAVLPLDAALYAEITKDRDEVKRCCECGATFTPKSNRAKYCAACSKRM
                     RRRKEAERQRKRYWKPTHLEL"
     gene            10835..11071
                     /locus_tag="ACG804_000513"
     CDS             10835..11071
                     /locus_tag="ACG804_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4831468.1"
                     /translation="MDGQEKLLDYETIKAAVAGERWATEKVLAHYADYINELSTVEIR
                     QANGKKKKVIDEDIRQRISLKLLEALPSFPLEQR"
     gene            complement(11371..11574)
                     /locus_tag="ACG804_000514"
     CDS             complement(11371..11574)
                     /locus_tag="ACG804_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-transfer assisting family protein"
                     /protein_id="HFS4831469.1"
                     /translation="MMHFTVEEENLICMYHNADRRRTINRLTAVMLVMDGDMRAQAQQ
                     TLSKLERMTDADYDGQKFHFTDE"
     gene            complement(11578..12522)
                     /locus_tag="ACG804_000515"
     CDS             complement(11578..12522)
                     /locus_tag="ACG804_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831470.1"
                     /translation="MQKFENVDVLAALEQIMRQNTAFYQSDFGIDKDIIRRDAASDQA
                     ADKTLLWMSRPSGTYCFRERDVFLKDTRQYNTWKFYGEQTRDKILAYAVELTGTQGGT
                     IRGNLYELDYPQHFRHVIETAQPVSVNRLFYEHGTRDIPESQRFDGSPDRVLGNFLYY
                     EAQPHDPAVLQEALRTEQHSRGRAVPGDFKVHVTALHDSRIETEARRIVDSLKDLSAP
                     NSPNKTHFMVEISPHFAAIASTKDNDRLFAMLPYKSLCFTGMKGRHGVYAVINRDERR
                     DVSIRRPRPSIRKQLSDSKQAASPKKAAARTKKNELEV"
     gene            complement(12523..16443)
                     /locus_tag="ACG804_000516"
     CDS             complement(12523..16443)
                     /locus_tag="ACG804_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002418674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YodL domain-containing protein"
                     /protein_id="HFS4831471.1"
                     /translation="MNEVFSIQVHNRQFLEQGKQGVWLDLPTTTETLQAALRDVGITA
                     DNPQDFFINGYSCPEDRHLAIPYDMVLAADVDELNFLAARLGQLDAAEIAELNAALQN
                     PRGGFENIGQIIDYTENVDYYVHLPDVRGDGQLGDYYLNRSGMVDMPEEWKAGIDTAQ
                     FGRHIAQQEQGVFTQYGYLVRSGDEWQRVHEGQPVPEEYRVMHYPQPEADREEPQAQQ
                     PEASESPDKAPPPVIPIMLDGMNSKERMKVITDRLETGVQELFESSRYMAYLSAMSKM
                     HDYSLNNTLLIAMQGGSIVAGYNRWQDEFDRHVKRGEKGIKILAPAPFKVKQQMEKID
                     PATQQPVIGADGKPVTEEQEVTVPAFKVVTVFDISQTEGKDFPMPYISELTGDVQQYQ
                     DFFAALERTSPYPISIEPISDGAKGRCFYAKQRIAINEGMSELQTLKTAIHEIAHAKL
                     HAIDREAPAEEQAARPDRSTREVQAESVAYTVCQYYGLDTSDYSFGYVADWSSGRELS
                     ELKASLETIRATASELITEIDGHFAQLQQEREARQEQEAVTVDVTPEAAAPAQAEEEQ
                     APALDPAAEPLVTVLWSESPQLKDGQQMPLHEADALFARLDAAYPAEAGYDKTAFRID
                     CIFQGEPDSYEGRQDFGDRDGSLIEHIQSYHQFYAQDENWKKHVIATTGIEGWEQDKA
                     HRDMLLGEFVPYMKLHCSLAQMEQTAQGRLQSGETLTPEETAYLGALLSYVQECRPML
                     NQGQYQLPEPPKLADFDQSLQDYKAQVQAEIAQEAAAAGMTVEEYAAAGYEAPQQDTF
                     SIYQLRGGEETRDYRFEPYERLQAAGLAVDSANYDLVYTAPLDKSTSLEDIYRTFNID
                     HPADFRGHSLSVSDVVVLHQNGQDTAHYVDSFGYMEVPEFLRENPLRTAELSTEQNEN
                     MIDGIINNTPPEPQPEEPEQLSFEDVAVASGQTQEEPPEAAPPQTAVRYYPINEGAAR
                     RAKEAMSFSDYRPGSATAEYRHYVDQAVEIAERQKKRVEPEYHEKIDSLLDTYARKLA
                     ENMNKGYEITARVPSVLIAGPSNFPVRAKEKQNAASDRNMEEFQYIQGLLDKIRSTGM
                     GGISADDPQAVSKLEKKLEKLEASQELMKAVNAYYRKHGTLDGCPHLTERGIENLKAD
                     MASGWHYEKKPFQSWQLSNNNAEIRRLKGRIEELTRQKEAAYVGWEFDGGTVEINRVA
                     NRLQIFFEGKPDAAVRDELKSNGFRWSPKAGAWQRQLNDTTIRVADRIKCIQPLSGEK
                     PSALQLAARREKEKPSIRAQLNAAKTEQAKQPPAREKSKGLEVE"
     gene            complement(16592..18673)
                     /locus_tag="ACG804_000517"
     CDS             complement(16592..18673)
                     /locus_tag="ACG804_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HFS4831472.1"
                     /translation="MTYKLVIAEKPSVARSIAGVIGATEKHDGYLEGNGYLVSWCIGH
                     LVSFADAGRYDERFKKWRYEDLPILPETWQYIVPDDKKQQFDVLCSLMQRPDVTGLVC
                     ATDAGREGELIFRFVYQMAGCQKPFERLWISSMEDSAIKDGFAHLKPGGDYDPLYQSA
                     LCRAKADWLIGINATRLFSVLYHKNLTVGRVQTPTLKMLVDRDAKITDFKKEKYHIVH
                     ITAGGADAVSSRFSDAAEANTVKAACAKAQAVCVSVTREKKTEQPPKLYDLTTLQREA
                     NRLFGYTAKQTLDYAQALYLKKLLTYPRTDSQYLTDDMLPAVESLVSGLWELVPFAKG
                     LNLSPQFDRILNSKKVSDHHAIIPTAEFVKQGFGTLAESEKKLLSLICCKLLCAVAGP
                     HIYEAVTATFTCAGQEFTAKGKTVLSPGWKEIERRFRSSLKTDADEDAEAVRELPELC
                     EGQTFADVAASVTEHFTTPPKPYTEDTLLSAMERAGAEDMPEDAERKGLGTPATRAAI
                     LEKLVQMGFVQRKGKQLIPTKDGINLAVVLPEALTSPQLTAEWENRLTEIAKGQADPD
                     EFMDGIETQARELVQTYSCISEEKQKLFQAERVPIGTCPRCGEAVYEGKKNYYCGNRA
                     CQFVMWKNDRFFEERKKAFTPKIAAALLKTGKVKVKGLYSVKTGKTYDGTVLLADTGG
                     KYVNYRIEHRS"
     gene            complement(18670..19899)
                     /locus_tag="ACG804_000518"
     CDS             complement(18670..19899)
                     /locus_tag="ACG804_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD1107 family mobile element protein"
                     /protein_id="HFS4831473.1"
                     /translation="MKNKTRRISRILPALLAVMLCVTAFPVTALAGGNDPAPAPLPEA
                     TTEPATGGLEPETDETGTATDGTETEAEKDTGPLTGKDITDLFSALFGSKVSIAATDD
                     GIQITTGTDKKEPEQTGTVTTNGGRLNVRTGAGLDKTAFTQLPNGTTVEVVGTDGDWI
                     KILLPERIGYVHSDYMTVSEKEVAATGEGGFSLSIDPEEIASLLELFNGGGASAALSP
                     DGNLSLIDDIGSAAKNGKQFITVETKNGNVFYLIIDRDDEGKETVHFLNQVDEADLLT
                     LMEDGETVTPAAVCSCTTKCKAGAVNTNCPVCKTNLTECSGPEPQEPQPEEPEAPEEE
                     PKGGAGGLIVFLLVALAGGGAALYYFKFKKPKAETTGSDDLGEYDFGEDEDLEDEEPE
                     TEFDPEADFVSEQEDEE"
     gene            complement(19889..20140)
                     /locus_tag="ACG804_000519"
     CDS             complement(19889..20140)
                     /locus_tag="ACG804_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HFS4831474.1"
                     /translation="MATKLDRIEKDIQKTKSKIAEFQKQLRELETQKTEQENLQIIQL
                     VRGMNMKPEEFAAFLRSGAMQAAPAATPYHEQEDNAHEE"
     gene            complement(20163..22154)
                     /locus_tag="ACG804_000520"
     CDS             complement(20163..22154)
                     /locus_tag="ACG804_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HFS4831475.1"
                     /translation="MKELKAKAKVTQAMTRDGLTLENQATGEVENISSREAEQDLSAP
                     GPGGTADKLLERADAIHDGHKAKKAAKQAGAVAAEGDAALHRPSARLQLSEEERADPD
                     LQPYIRKSDKRADKLDKARAAIPKKRVPVKETVFDEASGKAKTVLHFDKQDKGPPSLK
                     PNPAGRPVSEVFLFGHGKIHEVEHENVGVEGGHKGEELAERQAGKAIRSTIRHHRLKP
                     YWDAEKAERRLLSANAEYFYQKSLRDNPEIAQAASNPISRFWQKQQIKRQYAKAARTA
                     GQTAGAAAQGAAKTAGASTKAAKAAAKESERAASFVARHWKGALAVLVLGLLMLLIIG
                     GLQSCTAMFGSAGSGITASSYFSEDSDMLAAEDAYAELEAELQDYLDNYEATHDYDEY
                     HFDLDEISHDPYVLISILSALHDGIFTIGEVQGDLSMLFDKQYILTENVVVETRYRTE
                     TDTWTDAEGNTHTDTYQVPYDYYICYVTLENFDLSHVPVYIMDEETLSFYSLYMSTLG
                     NRPDLFSGSQYPNASTLTPPTYYDVPPEALEDATFAAMLKEAEKYIGYPYVWGGSSPS
                     TSFDCSGFISWVINHSGWNVGRLGAQGLYNICTPVSSSQAKPGDLVFFKGTYDTPGVS
                     HVGLYVGNNVMLHCGNPISYTNLTSNYWQSHFYSYGRLP"
     gene            complement(22186..24585)
                     /locus_tag="ACG804_000521"
     CDS             complement(22186..24585)
                     /locus_tag="ACG804_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4-like conjugal transfer ATPase, CD1110
                     family"
                     /protein_id="HFS4831476.1"
                     /translation="MSKKEIPRETEKTKLTRAQRKEIDAVIRKYKGDGRPHTAQQSIP
                     YEVMYPDGVCRVSPGVFSKCIEFADISYQLAQPDTQTAIFEKLCDLYNYVDASIHIQF
                     SFLNRKVDPVQYAKSFEIAPQGDDFDDIRAEYTGILQKQLANGNNGMVKTKYLTFTIE
                     AESVKAARARLKRIGFDLLGYFKSMGAVAHVMDGWERLNLLHGVYHPDGEIFNFDWKW
                     LAPSGLSTKDFIAPSSLCFGNAKTFGMGGKYGAVSFLQILSPELSDDMLADFLNTESG
                     VLVNLHVQAIEQTKAIKTIKRKITDLDAMKIAEQKKAVRSGYDMDILPSDLATYGEDA
                     KKLLTKLQTRNERLFQLTFLVLNVADTKQKLNNDVFQAAGVAQKHNCPLVRLDYQQEQ
                     GLASSLPLGVNQIKIQRSLTTSSVAVFVPFVTQELFQGGAAMYYGINAKSRNMIMLDR
                     KQARCPNALKLGTPGSGKSMSCKSEIVSVFLTTPDDIFISDPEAEYYPLVKRLHGQVI
                     RLSPTSKDFVNPLDINLNYSEDDNPLALKSDFVLSFCELVMGGKNGLEAIEKTVIDRA
                     VRVIYRPYLADPRPENMPILSDLHKALLDQHVPEADRVAQALDLYVSGSLNVFNHRTN
                     VDIGNRLVSFDIKELGKQLKKLGMLIVQDQIWGRVTANRSQGKATWYFADEFHLLLKE
                     EQTAAYSAEIWKRFRKWGGIPTGATQNVKDLLSSPEIENILENSDFITLLNQASGDRK
                     ILAERLNLSTEQQKYIDNSEPGEGLLIFENVVLPFTNPIPHNTQLYKIMTTRLNEVAG
                     V"
     gene            complement(24515..24937)
                     /locus_tag="ACG804_000522"
     CDS             complement(24515..24937)
                     /locus_tag="ACG804_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HFS4831477.1"
                     /translation="MAYVTVPKDLTHVKSKVVFGLTKRQLICFSGALVIGVPLYFLTR
                     DYLTNSAAALLMVFAMLPGFLLAMYERHGQPLEVVIMQIIQCCFIQPKERPYQTDNTY
                     TALVRQYQMEQEVKAIVQKGNPKRNRKNKADPRPAKRN"
     gene            complement(24951..25487)
                     /locus_tag="ACG804_000523"
     CDS             complement(24951..25487)
                     /locus_tag="ACG804_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MT-A70 family methyltransferase"
                     /protein_id="HFS4831478.1"
                     /translation="MSTYNIIYADPPWRYDCKNVQGAAENHYSTMSIDELCALPVERL
                     ASKDCLLFLWATFPMLPEALRLIKAWGFSFKTVAFVWLKQNRKSLTWFYGLGRWTRGN
                     AEICLLATHGKPKRRSASVHQFIISPIEQHSKKPDVTREKIVELAGDLPRVELFARQK
                     TPGWDVWGNEVECDLILT"
     gene            complement(25524..26387)
                     /locus_tag="ACG804_000524"
     CDS             complement(25524..26387)
                     /locus_tag="ACG804_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB6/TrbL-like conjugal transfer protein,
                     CD1112 family"
                     /protein_id="HFS4831479.1"
                     /translation="MISEIIEEWIKGILMDGITGNLSGLFDTVNAKVGEIAADVGRTP
                     QAWNSGIFNMLHSLSETVIVPIAGAILALVMCYELIQMITEKNNMHDFDSSMFFRWIF
                     KSAFAILIVTNTWNIVMGVFDATQSVVNQSAGVIIGQTSIDFNTLIPDLESQLEAMSV
                     GALLGLWFQTLVVGLTMNILSICIFLVTYGRMVEIYVVTSLGPIPLATMGNAEWRGMG
                     QGYLKSLLALGFQAFLIMVVVGIYAVLIQNIGSASDISGAIWGCMGYTVLLCFCLFKT
                     GSISKAVFGAH"
     gene            complement(26479..26694)
                     /locus_tag="ACG804_000525"
     CDS             complement(26479..26694)
                     /locus_tag="ACG804_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016147847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family mobile element protein"
                     /protein_id="HFS4831480.1"
                     /translation="MAFFNSAVTTLQTIVIGLGGALCVWGGINLLEGYGQDNPGAKSQ
                     GVKQLVAGGGVALIGVTLVPLLSGLLG"
     gene            complement(26771..28579)
                     /locus_tag="ACG804_000526"
     CDS             complement(26771..28579)
                     /locus_tag="ACG804_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirD4-like conjugal transfer protein, CD1115
                     family"
                     /protein_id="HFS4831481.1"
                     /translation="MKPDVKKLLILNLPYLIFVYLFAKCGEAYRLAAGADLSGKLLHF
                     ADGFAAAFANPLPSLHLFDLCIGIAGAVIVRLVVYCKSKNVKKYRKGMEYGSARWGTA
                     KDIAPYIDPKFENNILLTQTERLTMTGRPKDPKTARNKNVLVIGGSGSGKTRFFVKPN
                     LMQCFPTTDYPTSFVVTDPKGTLVLETGRMFQQAGYRIKILNTINFSKSMKYNPFVYI
                     HSEKDVLKLVNTLISNTKGEGEKSAEDFWVKSERLFYSALIGYIWYEAPAEEMNFSTL
                     LEMINASEAREDDPEFQSPVDLMFERLEQKDPDHFAVRQYKKFLLSAGKTRSSILISC
                     GARLAPFDIREVRELMEDDEMELDTIGDEKTVLYLIMSDTDTTFNFILAMLQSQLINL
                     LCDRADDVYGGRLPVHVRLILDEFANIGQIPNFDKLIATIRSREISASIILQSQSQLK
                     AIYKDAAEIISDNCDSVLFLSGRGKNAKEISDALGKETIDSFNTSENRGSQTSHGLNY
                     QKLGKELMSQDEIAVMDGGKCILQLRGVRPFLSEKFDITKHPRYKYLADADKKNTFDV
                     DRFLTITRRKRQQVVTQDEVFDLYEIDLSDEDAAAE"
     gene            complement(28576..29052)
                     /locus_tag="ACG804_000527"
     CDS             complement(28576..29052)
                     /locus_tag="ACG804_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HFS4831482.1"
                     /translation="MQEEVTQKTIALSMKTGKLTAQVLQAALKKYLQHRAKGKNTLHH
                     GQQSLKQLKKHGADLSNIEITEANIGAFKPCAKKYGVDFTLRKDKTTQPPHYVVIFKA
                     KDADNLDLAFREFTAKTLSKEQRPSIRKVLSAVKQKAAAQTKQRAKEKIKERGLEL"
     gene            complement(29127..29339)
                     /locus_tag="ACG804_000528"
     CDS             complement(29127..29339)
                     /locus_tag="ACG804_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HFS4831483.1"
                     /translation="MKQGALIFDERTDRYDIRFDLADYYGGLHCGECFDVMIGGKWRP
                     TRIEMAENWYLVGIRADDLSGLRVRI"
     gene            complement(29361..30326)
                     /locus_tag="ACG804_000529"
     CDS             complement(29361..30326)
                     /locus_tag="ACG804_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6017 domain-containing protein"
                     /protein_id="HFS4831484.1"
                     /translation="MAVFRVEKNKGYTVMSNHHLRNKNLTLKAKGLLSQMLSLPEDWD
                     YTLKGLSYINRESIDAIRTAVWELEKAGYIRREQGRDAKGKMADMVYTIYEQPVLENP
                     VLENPTSDNPVLENPTSDNPASENPTQLNKEVQRTDLSKKEKIITDGQSTHSIPIPSP
                     TPAPMEGEAAATPPERKRTGKDEAVRIYREIILENIEYAYLIQDRSIDREQLDEIVDL
                     MLETVCTARKTIRVAGDDYPAELVKSKYMKLTGEHIRFVLDCLRENTTKVRNIKQYLR
                     AMLFNAPSTISNYYTALVAHDMAQPDWGKPKSGLPDYSCGEGESL"
     gene            complement(30817..31338)
                     /locus_tag="ACG804_000530"
                     /pseudo
     CDS             complement(30817..31338)
                     /locus_tag="ACG804_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
     gene            complement(31354..32052)
                     /locus_tag="ACG804_000531"
     CDS             complement(31354..32052)
                     /locus_tag="ACG804_000531"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HFS4831485.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(32009..33670)
                     /locus_tag="ACG804_000532"
     CDS             complement(32009..33670)
                     /locus_tag="ACG804_000532"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004856 - D-xylulokinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0005998 - xylulose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HFS4831486.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKR
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            33888..35288
                     /locus_tag="ACG804_000533"
     CDS             33888..35288
                     /locus_tag="ACG804_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0051119 - sugar transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HFS4831487.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKVLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIIGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(35540..36619)
                     /locus_tag="ACG804_000534"
     CDS             complement(35540..36619)
                     /locus_tag="ACG804_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFS4831488.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(36705..37664)
                     /locus_tag="ACG804_000535"
     CDS             complement(36705..37664)
                     /locus_tag="ACG804_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HFS4831489.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(37676..39187)
                     /locus_tag="ACG804_000536"
     CDS             complement(37676..39187)
                     /locus_tag="ACG804_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046556 - alpha-L-arabinofuranosidase
                     activity [Evidence IEA];
                     GO_process: GO:0046373 - L-arabinose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-arabinofuranosidase C-terminal
                     domain-containing protein"
                     /protein_id="HFS4831490.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(39209..39772)
                     /locus_tag="ACG804_000537"
     CDS             complement(39209..39772)
                     /locus_tag="ACG804_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFS4831491.1"
                     /translation="MKIVETKFYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(39778..40641)
                     /locus_tag="ACG804_000538"
     CDS             complement(39778..40641)
                     /locus_tag="ACG804_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4831492.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(40655..41551)
                     /locus_tag="ACG804_000539"
     CDS             complement(40655..41551)
                     /locus_tag="ACG804_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4831493.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(41726..43015)
                     /locus_tag="ACG804_000540"
     CDS             complement(41726..43015)
                     /locus_tag="ACG804_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFS4831494.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(42987..44504)
                     /locus_tag="ACG804_000541"
     CDS             complement(42987..44504)
                     /locus_tag="ACG804_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HFS4831495.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            44702..45592
                     /locus_tag="ACG804_000542"
     CDS             44702..45592
                     /locus_tag="ACG804_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HFS4831496.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(45665..46489)
                     /gene="nadE"
                     /locus_tag="ACG804_000543"
     CDS             complement(45665..46489)
                     /gene="nadE"
                     /locus_tag="ACG804_000543"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HFS4831497.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(46501..47973)
                     /locus_tag="ACG804_000544"
     CDS             complement(46501..47973)
                     /locus_tag="ACG804_000544"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HFS4831498.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
BASE COUNT        11700 a        12082 c        10896 g        13433 t
ORIGIN      
        1 gaggggcaag gctttttttg agtggtggaa gtggattaga gcatggcaat agcaaaacag
       61 catagcggca tcctcctatg ggccgccaca ccttttgctg ccagaaaaga acggcggcct
      121 tgatttctca aaaccgccgc cagcaaaata caaaatgggc gtgggaaagg tctgcccaac
      181 agcggttttt ttcttttctg ccgctgggca gattgaatac tataatttgc aatgtattac
      241 aaaagatgct ttaaccactt tccagtaaaa gattgtccat gaccagcata gattttatca
      301 aatccaaaat ctgatacaaa accaatactt tcattatgaa acggcaaaat taaaataggt
      361 atcggggtat ggctcatcaa tcaacttata gtgccaccat tcaaagcgat aagactgaaa
      421 tccgctgctt tccatgattt tacgcaagca tcttcgattt tgtgcctctg catcccctat
      481 cccttttgct gtatgatgcg accgttcgtc cataaaatcg aagttacttc ccattgaaac
      541 aagttcccct gtatccaggt ggtagagcgt aagatcaatt gcgcttccac ggctatggct
      601 ggattgtgag gccacataac cctttgtaat caactcggct cgctctatat tggggtaaaa
      661 tttttctttt gtgagattgt cctccggttg cgctgcccaa cgcaggaagc agtccaccgc
      721 agttcttggc cgatatccat cccataaaag caagccatag ccaagcgcag ccgcatggat
      781 ttgtgcctcg cgcagagcaa acgccacggc ctttgtgccg atgatgcgat tcacctcata
      841 cccatccacc ggttttcctg tgaagttatc ccatgtggcg tacttggcat cccaacggac
      901 gccatgcaac atttcatcta aaaacaaaaa accattttcc atacttatca cctctttaac
      961 gccaatgtaa tcaggctgtc aatcagtgca ggaagcgtga ttcctgcggc ggccatcata
     1021 cgtgggtagc ggctgtacga tgtaaaaccg ggcagggtat tgacctcatt tagaacgatg
     1081 ccgccatcct cctgcaaaaa aagatcaaca cgggcaagcc ctctgcatcc aagcacccga
     1141 tatactttct ttgccgtttc ctgcacccga tttcgttcct cgaccggaat gtctgcggga
     1201 actgtaatca tcgcattttc tgagcctttt tccggctcgt tttcctgatg gatgcggaag
     1261 gtaccgtggc tcagccggat ttgatccact tcgccgacaa tcaaatcatc ctcgttcccc
     1321 atgaccgcac acccgacctc acagcccgaa atcgcttgct caattaagat ttttccatca
     1381 tattgtcctg ccgcttctat cgcagcgtta agttcttccg taccgtttac tttggttacg
     1441 ccaaaggacg aacctgaccg tgccggcttc acaaagacag ggtaggtaag cgcacccgcc
     1501 tccggcttgt cacctttatc aatcatttga aattcgggaa cggcgatgcc cgcatttttt
     1561 gtaagaatgt aggccagtga tttgtccatg caagctgcgg agctttgaat atcacagccc
     1621 acatagggga taccagacaa tacaaacagc ccctgtatcg caccatcctc cccgcatttg
     1681 ccatgcaaaa ccgggaaagc cacatcaata cgccgtgttt cgtattcgct ttctttcatg
     1741 acaagcagcc catgcgtttt cctatccggg gagagtatgg cggggagact gtcggcttcc
     1801 cattccgtac atggcttctt gcatagcttc catacaccgt tttttgtaat tccgatgtag
     1861 tgcggatcga atttttccgt atcaatgttc gcagcaattt ctattgcgga ttttaccgac
     1921 acatcatgtt cctccgagca accgccgaag atgattgcga cttttattct attcatgctg
     1981 taaactcctt tcaaaattga gacaattcct gattgttttt tctgtagtat cctgcagcac
     2041 acgctcagtg tagtacgccg tatggggtgt gatgatcaca ttcggcatcc ttaaaagctg
     2101 cgacaaaaag ggatggtcaa gcactttctg cgagcaatcg gtataaacaa actgatcctc
     2161 gccctccaac acatccagtg ccgcaccacc cagctttccg ctttccaacg cctccaccag
     2221 cgccccggta tcgacaagcg ctccgcgccc ggtgttgatt aaaaatgcgc cttgcttcat
     2281 ctctccaatt tgcttctgac cgatcagatg gcgggtatcc gcacaaagcg gcacatggag
     2341 cgtaacaata tcgctgtttt ttagaagctc atcaagctgg acataatctg catccatttt
     2401 tcggctgtta tcataggcca gcacatggca tccaaatccc cgcagccttt tgacgaccgc
     2461 ttgcccgata tggccggttc caataactcc cacagtcata tcccccagtt ctttcccccg
     2521 gatacgatcc aatctgaaat cttgttgcgc cacggcgtgc atggtgggtt ttgcaccccg
     2581 tatggccatc agcatcagca tcaaagcata atccgcaacg ctgtccggcg aatacgcaac
     2641 cgtgccaacc gagattccca ttctctcggc ggcagtcgta tcaatgtgat cgcagccgat
     2701 gctgcgggta gaaatgtatt ttaccccgac ctttctcagc gcaagaattg tcgcctcgga
     2761 aacctcggac ttatggccta cgctaacgca ttgattgcca gcggccaatt ttgcgttgtc
     2821 tgccgatatc gcatcgctaa tcagcgtagg gataatatga aaatccggcg ataaagcgcg
     2881 gaaagcattt gcctcatcct gttcgcatcc aaaaacagta atgcccacac tttttctcat
     2941 tggttctcct cctgaatatc cacactttcc gggaggggat aacagatttt gcatttgttt
     3001 gtataaagca gcttgcaatc tattatttcc ccggtaccta aggcaacttg catccgttta
     3061 acctgggcat attcataaat cccgccactt tcacggacat actggatact gccatttgta
     3121 attttgtata atgcttgggg ctctttgtcg gcggacacct gaccgatgat tttctcatca
     3181 tctaaggtca cccatatttg gtaggtgcag tcggtatcgt ttcgcacttt taaatcaatc
     3241 cagccctctg aaatggttgc atccacccct ttaatctcgt cactgtttgg ctctggaaac
     3301 tcctttactt cgtgacctct gcgctggata attgtcaatg gcgtatgcag gaacatccaa
     3361 aatagtaaat tgctcatctg gcacataccg ccgcccgaca tggtggtgag tttaccattg
     3421 gtcaccgtaa ggccgtcttt atagggggta tctttgtccg catggcgtac cagccaccag
     3481 aaagaaaagg gttcccccgg tcttatcaat aagccgttta aggtctttgc tgccagcttt
     3541 aagttgaaca ccttgttttc ctggtatatc atgtcaaatc cggtattgtg gttgtataat
     3601 gcgcaatccg tttcaaagag caaatgggaa agcgattttt cccctatcgt ctgcgcatag
     3661 cgacagccgt caaatctcat tcccgcataa aagcacattt ttctctgcgc ccgtctcatt
     3721 ggaagcagga acgggaaacg ctgtgtcaat ctttttctgt ccataacata acatcctttt
     3781 ctcatttttc tggttttaaa tattcctcaa ggcaaacccc ttggttgtac atctctgtgg
     3841 cagcttcgat gccaacatat cggtaatgcc acggctcgtt gctcacaccg gttatctctg
     3901 tcttgtctgg tgggtagcga cgaataaaac caaaacgata gctgttttca tccagccatc
     3961 tataaacctc gttgcctgtt gaatgaattc cgtccgcatt gatatccaca gcaagaccaa
     4021 gctgatgctc gctcgttccc ggcacggcca cccaagtttc tgcttccgct ttagcctgtg
     4081 cagaggtgta gcctttcgcc ttatattcgg caattttttc atccataatt tcttgctgtt
     4141 tttctgttgt tcggtatccg gatgcgacaa tcgggtaaac tccatcagtt cttgcggcat
     4201 caaacaaatc ttgaagatag ggagaaatcc gaatatctat ccgctcacca tttgatagtt
     4261 gctcaagctc cacatcgtac tgtgcgggga tggggttctg cctgttcact aaaatcaggc
     4321 tccattcctg ttcatctccc tgttctttgg cggtggcaag agcgttttcc tccaaattct
     4381 ccactacgtc agtgctgctg cctgtatgag ttgcagggat gggcggtatc tgtgttgcct
     4441 ccaatacgga agccagtctc cgccccaaaa acagcgtgca gactgtgaac gaaataatga
     4501 acgcacatag aaaagcccgc ttttccacgg attgtttcat atgccgtttg tgatgatccg
     4561 cattggaatg atagttgctt ttttccattt gatcgaatgc ctcctttgca ataaaactac
     4621 gatttgtggc tggtacgatt gttattatgg caagcgcatc tgtactttcc ctgtagccag
     4681 tctgtagttt tcctgtagca gcaaaaaaag accggcaggg ttatacctgt cggtcaaaat
     4741 catttaagtt ttaaatattt acaatgttga tgtgagcggt aaatccagcc agaacaaaac
     4801 gccatccgag gtgttttcca gcgcatactg gaggctcatg gcatccagcg ttttttgtac
     4861 gatggcaagt cctaaaccgc ttcgcccact ttttctgctt tgcgcctgat caatgcgata
     4921 gaatggggtg aacagccttg gaagcgcagt atcatcaatg tgaacgccca tgttcaaaac
     4981 aaaaaggcgg catttttcag caccaggctc actccatatc cgtacctcgc ctccctgcgg
     5041 cgtgttctga actgcattca atatgacatt ggatagtgcc ttttggagca gcctcggatc
     5101 ggacaggaca atttgcccgg ctggaatatc tgtgacgaac cgctggttgt ttgcctctgc
     5161 caaggtttga aaatcgggca gcaactcggc aaccgtgcgc cctatgtcca acggttcagc
     5221 tatgggtacg attctcccat cattcaggct gacaagctcc agtatttcgg aaatgatttt
     5281 gccctgccta tccatcattt tgatgcattc gcgcagatac ttagaatgat ctttgtagtc
     5341 accgatattt tcaagcattc cctccaacag aacgcttgta gccgcgatgg gcgtttttag
     5401 ctcatgagaa gctgccgcaa agaaatatcg ctgtgtttcc tccaactcat gttcccttgc
     5461 gatttcatcc tccagccttg cgatggtttc tttcagcctg acatacatgg aatgcatatc
     5521 atgagccagt gcgccaagct catcctttcg ctccagcggc ggcggtacat ctttcaggtt
     5581 tgccatttta ttcgcactgt ccgctaaggc tttgatcggc gttgtcattt gccgcgcaaa
     5641 gatatacgcg cataaaaggc tgaatacaac cattatcgca atcataacaa ttccccgaat
     5701 tgtcagccct tgataaagca atcccacacc tgccttgctt tgagcaacaa tcgaaatatt
     5761 atcatctcta tgtaccacat aaagaaagtc gggtctaaaa ctatttgatg tattggcatt
     5821 tggtgtggca tagagtacgc ttccctcttt atcttcaata taaaactcaa aggattggtt
     5881 attgtagtga aacagccctg ccacctcttg aatatcaagc ctatcgctat tctgaatcag
     5941 ttccaccaat ggctgatagg attttactgt ttgctgtaat tccatcactc tgaaataaga
     6001 cacaaattgc tgtgcaaaca gtgttgctgt tacaccgaca agcagtagca gggcaatgat
     6061 cgtataggaa aaaaccttaa tgaaaatccc ttttctttcc attattatga ttcctccaat
     6121 cggtatccta caccgcgaat ggttttgatg atattttccg gcagcttggc ccgcaaattt
     6181 ttgatatgag tgtggactgt gctgccatca ccctcaaagt catatcccca tatacgtgac
     6241 aaaatgattt catgcgttaa ggttctgcct ttgttctgca ccagcagcaa aaggatttca
     6301 aattcttttc gtgtcagggg cagctctgta ccgtcacaaa gtaccgtgaa atcctccggc
     6361 agaagtgtca gcctgccgac acggatttcc tttgccagcg caccgctgcg ccgcagcagg
     6421 gcttccaccc gctttagtaa aatctgcatc ttgaatggct ttgttacata gtcgtctgcc
     6481 tctgcatcaa acgcccggat ttggttttcg tcatccgaca gggctgtcat catcagaatg
     6541 ggagtatcat ttttcgcacg aaattcacgc aaaagttcat gcccgttcat accgggcagc
     6601 ataatatcaa gaataaccag ttgataagtg ttttcgtaaa acttggtgta tgcctcattt
     6661 ccatctgtgc aggcatccac ctgatatcct gcctcagcca gaaacgccct tactgtatta
     6721 cagatatgat catcatcctc gacaagtaga attcgtatcg acataaaaat ccctccattt
     6781 taagaagata acataacagt ctgtagtttc cctgtagttt caaagcgatt tcttttcgga
     6841 ttttaatcat ccgtcattgg gatactcgct tcttttcatg gtgtatgtat ctatattatt
     6901 ggtttaaacg aattaaatca agataataat aattaacacc ttcttaatgt ttgggatgtt
     6961 tcgattacag cggttgtcaa aacatcccga taatactggc aagcaatgga tcagaatatc
     7021 ctttacggat attctgatcc accacttgcc cgcctgcggc gttctcgttt tgcttgttgg
     7081 ggacacccca agcctcagca aaatgcgcgg cctctttttt gcgaatgcac cttgcggtat
     7141 ggcttttcac acaggcaggg cctgtgtgta ctccctccgg tcgctcttgc cgcactccgc
     7201 gcagcagatt cagtcctaat accgttcaag acagtagaaa atcagcaagt ctatattcct
     7261 catatcttca tcatccgtgt ccttgcagtt acaggaaatg taataatcgc caaatgtaaa
     7321 tcccagaata ttttcctcaa aaagccgtac ctccccggta ttaaaatcaa tcaccccata
     7381 ctcaaaggcg cattagacca gcagttatcc aatgtctgga gacttcacca taaagaatcc
     7441 agatgccggc cttttcaatt ctaccatata cggctgatac agcagcagct tcctcgtctt
     7501 tgtttcgggc attttccatt tctgtcatga taaagtttcg cttcttcata catccatgtg
     7561 taaatctttt ctttctgttt cagatgagaa tactttttat cggtctggag cagcctgcca
     7621 tctatcatct tatagttttt ccgtgacaaa ataccatgct ttctctctct tcaaaaccat
     7681 atccaaaatg cgccggtttc attatactat tcagtaaccg cctttccttt ctttgtacgc
     7741 ctgtcaatcg gcttttccgc agttttggga atgagccaga tcgtcgccat ctttacagcg
     7801 ccggggatgc gtcccgcagc acaatagtag tttatccatc gtgggggcac accccatttc
     7861 tcgcctgcct ctttcaacgt catgtagtcc atagtacacc tccacagggt acattataat
     7921 tcttttgctc gaagaataaa agaaacaaaa tgtgaaatat aaactttaag aaaggtgcat
     7981 ataccaacat tccacgggca gagtatgaaa tatacaatgt aagtgggagg tgcgatatgg
     8041 cgaatattga agattgtccc ggctttgaaa ctttcggcgc ggatgtgaaa gcggcccggc
     8101 aagcaaagcg cgtttcgcgc aaagcaatgg cagagaaaat aaatattgac tggcgctatc
     8161 ttgccaacat cgaaaacgac ggggccattc ccagtctgcc ggttgtcata cagcttatta
     8221 aagcctgcgg gcttcctgtg gaacgctact ttaacccgga gatcatgcgg gaggaaagcg
     8281 aactgcggca aagggtcagc cacaagctga aactctgccc cgaagaatac ctgccgatca
     8341 tcgagggcgc gattgacagc gccatactaa ttgaaaagcc gaagaagaat gaaacggagg
     8401 atgtgtaact ggcatcctct gttttacttt tagcgggagc tgcacagcgt agcttctatt
     8461 tttttgcact tttttctttc cagagggcta ttttgcgggt agtttggggc tttggaaacg
     8521 tcttgttagt ggagaaacag taacgtagca agcataggga gtgtagccac tcccggaaaa
     8581 acggcctgcc ccgtccctgc cgggccgcgt ccgttttgct tgttggggaa atccccaaac
     8641 ccctgaatgg aaaggacggt gaagcatggc aaacagaaag cgaaaaatcg tgctgcgcgt
     8701 ccctgtgacg ccggaggaac gggctatgat tgaacagaaa atggcgctgc tgcatacgaa
     8761 gaacttttca gcctacgccc ggaagatgct cattgacggc tatatcgtca acatggacac
     8821 cagcgacatc cgggcgcaga ccgccgagat acagaagatc ggcgtcaacg tcaatcagat
     8881 tgcaaagagg ctgaacggta tggggccggt gtacgcacag gacatcgagg atataaaggg
     8941 ggcgctggcg cagatatggc agttacaaag atacatccta tcaagtcaac gctgaaaaaa
     9001 gcccttgact acatcgagaa cccggacaaa actgacggca agctgctggt ggcctccttt
     9061 gcctgctctt atgaaacagc ggacattgaa tttgaaatgc tgctggcgca ggcataccaa
     9121 aagggcaata atctgggcca ccacctgata caatcctttg cccccggcga agccacgccg
     9181 gaacaggccc atgagatcgg gaagcagctt gccgaggaag tgctgcaagg gaaatatccc
     9241 tatgtgctga ctacccatat tgataagggc cacgtccaca atcacattat tttctgtgcc
     9301 gtggatatgg taaatcagcg caagtacatt tccaacaaac agagctatgc ctatatccgg
     9361 cgcaccagcg acaggctgtg caaggaaaac ggattgtccg tggtgaagcc cggccagagt
     9421 aagggcaaga gctatgccga gtgggacgcc cagcggaaag ggacgagctg gaaagcgaag
     9481 ctcaaagcag ccattgacgc cgctatcccg caggcaaaag attttgatga tttcctgcgg
     9541 ctcatgcagg cgcaaggcta tgagatcaag ccgggaaagt ttatttcttt ccgcgctccc
     9601 ggacaggaac gctttacccg ctgcaagaca ttgggggaag cctacaccga ggaagccatc
     9661 aaagagcgta tcaaaggccg cgttatcacc agagcgccca aagagcgcaa ggggatttct
     9721 ttgcggattg atctggaaaa caacattaag gcccagcagt cggcaggcta tgagaggtgg
     9781 gcgaagctcc acaatttgaa gcaggccgca aagactttga atttcctgac tgaacatggg
     9841 atagacacct acccggattt ggaaagcaaa gtggccgaga tcaccgccgc cagcgacgag
     9901 gccgccgcta ccctcaaagc tatggaacac cggcttgcgg atatggcggt gctgataaag
     9961 aatatttcta cctacaagca gctctggccc gtggctatgg aataccgcaa tgcagcggat
    10021 aaggcaaaat tccggcgtga gcatgaaagc acgttgattt tgtatgaagc tgcggcaaag
    10081 gccctaaagg gacagggtgt gaaaaagctc cccgatctgt acgccctgaa agccgagtac
    10141 aagcgattgg ccgaggaaaa ggaacggctg tatgagaagt acggcgaagc gaaaaagcag
    10201 atgcaggaat acggcatcat caagcagaat gtggacggca ttttgcgtat gacgccggga
    10261 aaggaatgga cgcaagagct atgagtattc cacgaatgaa ttaccctcaa tatcgcaagg
    10321 cccggaagct gacgcatgag tgctgcaact attgtgacgg caactgcctg ttgctggacg
    10381 acggcgaaga atgtatttgc gtacagagca tttcctattc gcttctgtgc cgctggttta
    10441 aggccgctgt cctcccgctg gatgcggccc tgtatgccga gatcaccaaa gaccgggacg
    10501 aagtgaaacg ctgctgtgag tgcggggcca cgttcacgcc gaagtctaac cgggccaaat
    10561 actgcgcggc ctgctccaaa cggatgcgcc gccgcaaaga ggccgagcgc cagcggaaaa
    10621 gatactggaa acctacgcac ttagagctgt aaaagccctt atatttcaag gcttttccgg
    10681 catggtcagc ggggtatgtg ggtgttttat cctatccccg ccgaagtgct gttctaaatg
    10741 cgtagaattt accagcagaa aagcgccgtt ttctctggtt ccatgcttcc gaatatggta
    10801 tcatagaaaa aatcagtctg acgggggtat caggatggac ggacaagaaa agctgctgga
    10861 ctatgaaacg atcaaagccg ccgttgccgg tgagaggtgg gccacggaaa aagtgttggc
    10921 ccattatgct gactacatca acgagctttc cacggtggag atcagacagg caaacggcaa
    10981 aaagaagaaa gtcattgacg aagatatacg gcagcgcatt tccctgaaac tgctggaagc
    11041 attgccgagc ttcccgctgg aacagagata gacggcaaga gggctgcacc ctcttacgcc
    11101 gctttgcggc tatcacctgc acacccctga aacagataca cccgctgcgc ggctatatct
    11161 gtttcagggg tctaattata gctgcaacct acgcatttaa gggattgaaa accgcccgct
    11221 gcaaggcttc tcccgcatgt ttgcaggggc aagcgaatac ttcatcctat ccccgacaat
    11281 accgggttct aaatgcgtag gaataggcaa aaagaaaaga cgccggacgc aagcgaccac
    11341 atggccgccg cgcccggcgt ctgctgttcg ttattcgtct gtgaagtgga acttctggcc
    11401 gtcatagtcg gcatccgtca tgcgttccag cttggaaagg gtctgctggg cctgcgcccg
    11461 catatcccca tccataacca gcatgacggc ggtgagcctg tttatcgttc tgcgccggtc
    11521 tgcattgtgg tacatacaga tcaggttttc ttcctccacg gtaaagtgca tcattcctta
    11581 tacctccaat tcattctttt tggttctggc cgccgccttt tttgggctgg cggcctgttt
    11641 gctgtcggat agctgcttgc ggatagaggg ccggggcctg cgaatactca catcccggcg
    11701 ctcgtcccgg ttaatcacgg catacacgcc atgcctgcct ttcatcccgg taaaacacag
    11761 ggatttatag ggcagcatgg caaagagccg gtcattatcc ttggtggaag caatcgccgc
    11821 aaagtgcggg gagatctcca ccatgaaatg cgttttattg gggctgttag gcgcggacag
    11881 atctttcagg ctgtccacaa tacgccgggc ctcggtttca atccggctgt catgcaaagc
    11941 ggtgacgtgg actttgaaat cgccggggac ggcccgcccc cggctgtgct gctccgtccg
    12001 tagcgcctcc tgcagcacag ccgggtcatg gggctgggcc tcatagtaca aaaagtttcc
    12061 caatacccgg tcagggcttc cgtcaaaacg ctggctctcc gggatgtcac gggtgccatg
    12121 ctcataaaag agccggttca cactcaccgg ctgggcggtt tcaatgacgt gccggaaatg
    12181 ctgcggatag tccagctcat agagattgcc ccggatagtg ccgccctgtg tgccggtcag
    12241 ctccaccgcg taggccagta tcttgtcacg ggtctgctcc ccgtaaaatt tccatgtgtt
    12301 gtactgtcgg gtgtctttca ggaaaacatc acgttcccgg aaacagtacg tcccggaggg
    12361 ccgggacatc cagagcaggg tcttgtctgc ggcctgatcg ctggcggcat cccgcctgat
    12421 aatgtctttg tcaatgccaa agtcactttg ataaaacgcg gtgttctgcc gcatgatctg
    12481 ttccagcgcg gccagaacgt ccacattttc aaacttctgc atttactcta cctccaatcc
    12541 ctttgatttt tcccgcgccg gtggctgctt ggcctgttcg gtcttggccg cgttgagctg
    12601 cgcccggata gagggctttt ctttctccct gcgggccgca agctgtaagg cgctgggctt
    12661 ttcgccggaa aggggctgga tgcacttgat acggtcagcg acgcggattg tggtgtcgtt
    12721 taactgccgc tgccatgccc cggccttggg cgaccagcgg aaaccgttgc ttttcagctc
    12781 gtcgcgtaca gcagcatccg gcttcccctc aaagaagatt tgcaggcggt tggccacccg
    12841 gttgatctcc acagtgccgc cgtcaaactc ccatcccaca taggccgcct ccttttggcg
    12901 ggtcaattcc tcaatgcggc cctttaaccg gcgtatctcg gcgttattgt tggagagctg
    12961 ccaggactgg aacggttttt tctcatagtg ccagcccgac gccatatccg ctttcaggtt
    13021 ttcaatgcct ctttcggtca gatgggggca tccgtccagc gtcccatgct tgcggtagta
    13081 ggcattgacg gccttcatca actcctgcga cgcttccagc ttttccagtt tcttttccag
    13141 cttggaaacg gcctgcggat cgtcggcgct gataccaccc atgccggtgc tgcggatttt
    13201 gtcaagcaag ccctgaatgt actgaaattc ctccatgttg cggtcactgg cggcgttctg
    13261 cttttctttc gcccgtaccg ggaaattgga cggcccggca atcaggacag aggggacgcg
    13321 ggcggtaatc tcatagccct tattcatgtt ctcggccagc ttgcgggcgt aggtgtcaag
    13381 gaggctgtct atcttttcgt gatactctgg ctccacacgc tttttctggc gctccgcaat
    13441 ttccacggcc tgatcgacat agtgccggta ttccgccgtg gcgctgccgg gccggtagtc
    13501 agaaaagctc atggcttcct tggcgcggcg ggcggctccc tcattgatgg gataatagcg
    13561 gacagccgtt tgcgggggcg cagcctccgg gggttcctcc tgtgtctggc cggaagcaac
    13621 tgccacatcc tcaaaagata gctgttcggg ttcctccggc tgcggttcgg gcggcgtatt
    13681 gttgataatg ccgtcaatca tgttttcgtt ctgctccgta gacagttcgg cggtacgcag
    13741 gggattttcc cgcaaaaact ccggcacttc catatagccg aagctgtcta catagtgggc
    13801 ggtgtcctgt ccattctggt gcagcaccac cacgtcggaa acggaaaggc tgtgtcccct
    13861 aaaatctgcc gggtggtcga tgttgaatgt gcggtaaata tcctccaaag acgtgctttt
    13921 atccagcggt gccgtataaa caaggtcata gttggcactg tccacggcca gccctgcggc
    13981 ctgtaaacgc tcgtatggct caaaccgata gtcgcgggtt tcctccccgc ctcgaagctg
    14041 gtagatggaa aaggtgtcct gttggggtgc ttcatagcca gccgccgcgt attcctccac
    14101 ggtcataccg gctgcggcgg cctcctgcgc gatctcggcc tgtacctgtg ctttgtagtc
    14161 ctgcaagctc tggtcgaagt cagccagttt cggcggctcc ggcaactgat actggccctg
    14221 attgagcatg gggcggcact cctgcacata agagagaagc gcccccaaat aggccgtttc
    14281 ctccggcgtc agggtttccc cggactgtaa gcggccctgc gccgtctgtt ccatttgggc
    14341 aaggctgcaa tgcagcttca tataggggac aaactcgcct aacagcatat cccgatgggc
    14401 cttgtcctgc tcccagccct ctatgccggt tgtagcgatt acatgctttt tccagttttc
    14461 gtcctgcgcg taaaattggt ggtagctctg gatatgttcg atcagggaac cgtccctatc
    14521 tccaaaatcc tgccgcccct cgtagctgtc cggctcgccc tgaaagatac agtcaatgcg
    14581 gaacgcggtt ttgtcatagc ctgcctctgc cggatatgct gcatccagac gggcaaacag
    14641 cgcgtcggcc tcatgcaacg gcatttgctg gccgtccttt agctgggggc tttcgctcca
    14701 tagcacagtc acaagcggct cggctgccgg atcaagggcc ggggcctgtt cttcctcggc
    14761 ctgcgccggg gccgctgcct ccggggtaac gtcaaccgtg acggcctcct gttcctgccg
    14821 ggcctcgcgc tcctgctgaa gctgggcaaa atggccgtcg atctcggtta tcaattcgct
    14881 ggccgtggcc cggatggttt caagggaggc tttcagctcg gataactccc tgccgctgct
    14941 ccaatcggcc acatagccaa aagaatagtc cgacgtgtcc agcccgtaat actggcagac
    15001 ggtataggcc acgctttcgg cctgtacctc gcgggtgctg cggtctggcc gggccgcctg
    15061 ttcctcggcg ggggcctccc ggtcaatggc gtggagcttg gcatgggcaa tctcatggat
    15121 ggcggtcttt agggtctgca attcgctcat gccctcgttg atggcaatgc gctgttttgc
    15181 gtagaagcag cggcccttgg ccccgtctga aatcggctca atgcttatgg gatagggtga
    15241 tgtccgttcc agcgcggcaa agaaatcctg atactgctgc acgtcgccgg taagttcact
    15301 gatatagggc atgggaaaat ccttgccctc ggtctggctg atgtcaaaga ctgtcaccac
    15361 cttaaaggcc ggaaccgtca cttcctgttc ttcggtcacg ggcttgccgt ccgcgccgat
    15421 cacgggctgc tgggtggccg ggtcgatttt ctccatctgc tgcttaacct tgaacggggc
    15481 cggggccagt atcttaatgc ctttctcgcc ccgcttcaca tggcggtcaa attcatcctg
    15541 ccacctgtta tagcccgcca caatcgaacc gccctgcatg gcgatcagca gcgtattgtt
    15601 cagactgtaa tcgtgcatct tggacatagc ggataagtaa gccatatagc ggctactttc
    15661 aaaaagctcc tgtacgccgg tttccagacg gtcagtaatc actttcatgc gttctttgct
    15721 gttcatgccg tccagcatga tcgggataac cgggggcggc gctttgtcgg ggctttcgga
    15781 tgcctccggc tgctgggcct gcggttcctc ccggtcagct tccggctggg ggtagtgcat
    15841 cacccggtat tcctccggca ccggctggcc ctcatggacg cgctgccatt cgtcgccgct
    15901 tctcaccaga tagccgtact gggtaaaaac gccttgttcc tgctgggcaa tgtggcgtcc
    15961 aaactgcgcc gtatcaatcc cggctttcca ttcctccggc atatccacca tgccggaacg
    16021 gttcaggtag tagtcgccca actgtccatc ccccctaacg tcgggaagat gcacatagta
    16081 atccacattt tcggtgtagt cgatgatctg gccgatattc tcaaagccgc cacggggatt
    16141 ttgcagggcg gcgttcagct ctgcgatctc ggcggcgtca agctggccca gccgggcggc
    16201 aaggaaattc agctcgtcca cgtcggcggc cagcaccatg tcatagggaa tggcaaggtg
    16261 tctgtcctcc gggcaggaat acccgttgat aaaaaaatcc tgcggattgt cggcagtaat
    16321 gccaacatcc cgcagggcgg cttgcagcgt ttcggttgtg gtgggcaaat ccagccagac
    16381 gccttgtttg ccctgttcca aaaactgccg gttatggact tggatagaaa atacttcgtt
    16441 cacgcggtca ctcctttctc tgttctgttt caaaaaatag ggggttgggg acttccccaa
    16501 caagcaaaaa tccccggccc ggcagggacg cggccggggg attttaccgg gagtgtagcc
    16561 acactcccta tgcttgctgt gttactgtcc tttagctcct gtgttcaatg cggtagttga
    16621 cgtacttgcc cccggtatca gccaaaagca ccgtcccgtc gtaggttttg ccggtcttta
    16681 cggaatagag gccctttacc ttgactttgc cggttttgag cagcgcagcg gcgatcttcg
    16741 gggtgaacgc tttcttgcgt tcctcaaaaa atcggtcatt cttccacatg acgaactggc
    16801 aggcccggtt tccgcagtag tagtttttct tgccctcata gacagcctca ccacagcggg
    16861 gacacgtccc gataggaaca cgctcggcct gaaacaattt ctgcttttcc tcactgatac
    16921 aggaataggt ctgcaccagc tcccgcgcct gcgtctcgat gccgtccata aattcgtcag
    16981 gatcggcctg ccccttggcg atctcggtca gccggttttc ccattcggca gtaagctggg
    17041 gagaagtaag cgcctccggc agcaccacag ccagattgat gccgtccttg gtgggaatga
    17101 gctgcttgcc ttttctctgg acaaagccca tctgcaccag cttttccaga atggcggcgc
    17161 gggtggccgg tgtgcctaat cccttgcgct cggcatcctc cggcatatcc tcggccccgg
    17221 cccgttccat agcggacaaa agcgtatctt cggtgtaggg cttgggcggc gtggtgaaat
    17281 gctcggtgac agaggcggcc acgtctgcaa aggtctggcc ctcgcaaagc tccggcagct
    17341 cccgcaccgc ctcggcgtcc tcgtcggcgt cggtctttaa ggaagaacgg aaccggcgtt
    17401 caatctcttt ccagccgggg gaaaggacgg tcttgccctt ggcggtaaac tcctgcccgg
    17461 cacaggtaaa tgtggcggtg acggcctcat agatatgcgg cccggccacg gcacataaga
    17521 gcttgcagca gatcagggac agcagctttt tttcactctc ggccagagtg ccaaagccct
    17581 gcttcacaaa ttcagcggtg gggataatgg cgtggtggtc ggacaccttt ttgctgttca
    17641 ggatgcggtc aaactgcggg gaaaggttca ggcccttggc aaacggcacc agctcccaca
    17701 ggccggacac aaggctttcc acggcgggca gcatatcgtc ggtaagatat tgactatccg
    17761 ttctcggata ggtcagcagc ttctttagat acagtgcctg ggcatagtca agggtctgct
    17821 tggcggtata gccgaaaagc cggttagcct cccgctgcaa ggtggtaagg tcatagagct
    17881 tgggcggctg ttccgtcttt ttctcccgcg tcacggaaac gcaaacggcc tgcgcttttg
    17941 cacaagccgc cttgacggtg tttgcctcgg cagcgtcgga aaagcggctg cttaccgcgt
    18001 ccgcgccgcc cgccgtgata tggacgatgt gatatttctc tttcttgaaa tcggtaatct
    18061 tggcgtccct gtccaccagc atttttaagg tcggcgtctg gacgcggccc acagtcaggt
    18121 tcttgtggta caggacggaa aaaagccggg tggcgttaat gccgatcagc cagtcggcct
    18181 tggcccggca cagggccgat tgatacagcg gatcatagtc gccgcccggt ttcaggtggg
    18241 caaagccgtc cttaatagca ctgtcctcca tagaggaaat ccaaaggcgc tcaaagggct
    18301 tttggcatcc cgccatctgg tagacgaaac ggaaaatcaa ttccccctcg cgcccggcgt
    18361 cggtggcgca cacaaggccg gtcacgtcgg ggcgctgcat cagcgaacag agaacgtcaa
    18421 actgctgttt cttgtcgtcg gggacgatgt actgccatgt ttccgggaga atgggcaaat
    18481 cctcatagcg ccattttttg aaacgctcgt catagcgtcc ggcgtcggca aaggacacca
    18541 gatgtccgat gcaccagctc accagatagc cgttcccctc caaatagccg tcgtgtttct
    18601 ccgtggcccc gatcacgccc gcaatgctgc gggccacgct gggtttttcc gcgattacaa
    18661 gtttatatgt cattcctcgt cctcctgttc actcacaaaa tcagcttccg ggtcaaactc
    18721 ggtttcgggt tcctcgtcct ccaaatcctc gtcctcccca aaatcatact cgcccaaatc
    18781 gtcgctgccg gtggtttcag ccttgggctt tttgaacttg aaatagtaaa gggccgcacc
    18841 gccgcccgcc agcgccacca gcaggaacac gatcaggccg cccgcgccgc ccttgggttc
    18901 ttcctccggg gcttcgggtt cctccggctg gggttcctgc ggctccgggc cgctgcactc
    18961 ggtcaggttg gttttacata ccgggcaatt cgtgttcaca gccccggcct tgcatttcgt
    19021 ggtacaggag cagacagcag cgggggtgac ggtttccccg tcctccatca gcgtcagcag
    19081 atcggcttca tccacctgat ttaagaaatg gacagtttct tttccctcgt cgtcccggtc
    19141 aataatcaga taaaacacat tgccgttttt ggtttccacg gtgataaact gcttgccatt
    19201 tttcgcggcg ctgccgatgt cgtcaatcag tgacaggttc ccgtccgggg acagggcggc
    19261 gctggccccg ccgccattga acagttccag cagagaagca atttcctccg ggtcaatgga
    19321 gagggaaaaa ccgccctcgc cggtagccgc tacttccttt tcgctgacgg tcatatagtc
    19381 ggaatggaca tagccgatgc gctccggcaa gagaatttta atccagtcgc cgtctgtgcc
    19441 gactacctca accgtcgtcc cattgggaag ctgggtgaac gcggtcttgt caagccccgc
    19501 gccggtgcgg acattcagcc tgccgccgtt ggtggtgacg gtgccggtct gttcaggttc
    19561 ttttttgtcg gtgccggtgg tgatctggat gccgtcgtcc gtggcggcaa tgctcacctt
    19621 ggaaccgaac agcgcggaaa acaggtcggt gatgtccttg ccggtcagag ggccggtatc
    19681 tttttcggcc tcggtttctg tcccgtccgt ggcggtgccg gtttcgtctg tttcaggctc
    19741 caaaccgccc gtagcgggtt cggttgtagc ctccggcagc ggggccggtg ccgggtcatt
    19801 gccgcctgca agggcggtaa cgggaaaggc cgtgacgcag agcatcacgg ccagaagtgc
    19861 ggggagaata cgggaaatcc gtctggtctt attcttcatg ggcattgtcc tcctgttcat
    19921 ggtaaggggt tgcggcaggg gcggcctgca ttgcgccgct gcgtaagaac gcggcaaatt
    19981 cctccggctt catgttcatg ccgcgcacaa gctggatgat ctgcaaattc tcctgttcgg
    20041 ttttctgcgt ttccagctcc cgaagctgtt tctgaaactc cgcgatctta gacttggttt
    20101 tctggatgtc cttttcgatg cggtcaagtt tggttgccat aattgaaagc tcctttctgg
    20161 cgttaaggta aacgcccgta actgtaaaaa tgggattgcc agtagtttga agtaaggttc
    20221 gtgtaggaaa tcgggttccc gcaatgcagc atcacattgt tgcccacata caggccgacg
    20281 tgggacacgc cgggggtgtc gtaggttccc ttgaaaaata caaggtcgcc gggcttggcc
    20341 tgcgaactgg aaacaggggt gcagatgtta tataggccct gcgcccccag ccgtcccacg
    20401 ttccatccac tatgattgat tacccacgaa atgaagccgc tgcaatcaaa gctggtgctg
    20461 ggagagctgc cgccccacac atagggataa ccgatatatt tttccgcctc tttgagcatg
    20521 gcggcaaagg tggcatcctc caaagcctcc gggggtacgt cgtagtaggt cggcggcgtc
    20581 agggtggagg cgttggggta ctggctgccg gaaaacagat caggccggtt tcctagcgtg
    20641 gacatataca gggaatagaa acttagcgtt tcctcgtcca tgatatagac tggcacatgg
    20701 gacaggtcga agttttccag cgtgacgtag cagatgtaat agtcatacgg cacttggtag
    20761 gtgtctgtat gggtgttgcc ctccgcgtcc gtccatgtat cggtttcggt gcggtaacgg
    20821 gtttctacca cgacgttttc tgtcaggata tattgcttgt caaagagcat ggacaaatca
    20881 ccctgtacct ccccgatggt aaatatcccg tcatggagcg ccgacagaat ggaaatcagc
    20941 acataggggt catggctgat ctcgtcaagg tcaaaatggt attcgtcata gtcatgggtg
    21001 gcctcgtagt tgtccagata gtcttgcagc tcggcttcca gctccgcgta ggcgtcctcg
    21061 gcggccaaca tatcgctatc ctcggaaaag taagaggacg ccgtgatgcc gcttccggcg
    21121 ctgccgaaca tggcggtgca ggactgtaag ccgccgatga taagcagcat caaaagcccc
    21181 aacacaagga cggccagcgc ccctttccag tggcgggcca caaaggaggc cgcccgttca
    21241 ctttctttgg ctgcggcctt ggccgctttc gtggaggccc cggctgtctt ggccgcgccc
    21301 tgtgccgccg cgcctgcggt ctggcccgct gtccgggcgg ccttggcgta ctggcgcttg
    21361 atctgctgtt tctgccagaa ccgggaaatg gggttgctgg ccgcctgtgc gatctccggg
    21421 ttatcccgca aagatttctg gtagaaatac tccgcgttgg cagacaatag cctgcgctcg
    21481 gccttttccg cgtcccagta gggtttcagc ctgtggtgcc ggatggtgct gcggatggct
    21541 tttccggcct gccgctcggc aagttcctcc cccttatggc cgccctccac acccacgttt
    21601 tcatgctcga cttcatggat tttcccgtgg ccgaatagaa aaacctcgga aacaggacgg
    21661 cctgccggat tgggtttcag ggagggaggc cccttgtcct gtttgtcaaa gtgcaggacg
    21721 gtctttgctt tgccgcttgc ctcgtcaaag acggtttcct tgaccgggac gcgcttcttg
    21781 gggatggcgg cgcgggcctt atccagctta tcggcccgtt tgtccgattt tcggatatag
    21841 ggctgtaaat ccgggtcggc ccgttcttcc tccgacagtt ggagccgggc ggatggccgg
    21901 tgcagggcag cgtccccctc ggcggccaca gccccggcct gcttcgcggc tttcttggcc
    21961 ttatggccgt catggatggc gtcggcccgt tccagcagct tatcggcggt gccgcccggc
    22021 cccggcgcgg acaaatcctg ttcggcctcc cggctggaaa tgttctccac ctcgccggtg
    22081 gcctgatttt ccagcgtcag cccgtcgcgg gtcatggcct gcgtcacttt cgccttggct
    22141 ttcagctctt tcatggtggt tcacctcctt tgtggcgtcg ccgggtcata ctcccgccac
    22201 ctcgtttaag cgggtcgtca taatcttgta aagctgggtg ttgtgcggga tggggttggt
    22261 aaagggcagc accacgtttt caaagatcaa aaggccctcg ccgggttcgg aattgtcgat
    22321 gtacttctgc tgttcggtgg acaaattcaa gcgttccgca aggatttttc tatccccgga
    22381 cgcctgattg agcagcgtaa tgaagtcgct gttttcaagg atattttcaa tttccgggga
    22441 ggaaagcagg tctttgacgt tctgggtggc acctgttgga atgccgcccc atttcctaaa
    22501 ccgcttccaa atctccgcag aataggccgc cgtctgttcc tctttcaaaa gcaaatggaa
    22561 ctcgtcggca aaataccatg tggcctttcc ttggcttcgg ttggccgtga cgcgccccca
    22621 tatctggtct tggacaatga gcatccccag ctttttgagc tgcttgccca gctccttaat
    22681 gtcaaaggac acaagccggt tgccgatgtc cacgttggta cggtggttaa atacgttcag
    22741 ggagccggac acatacaggt caagggcctg cgccacccgg tcagcctccg ggacatgctg
    22801 atctaacaac gctttgtgga ggtcggacag gatcggcata ttctccgggc gggggtctgc
    22861 cagatagggc cggtagatca cgcgcacagc ccggtctatc acggtctttt caatggcttc
    22921 cagcccgttc ttgccgccca tgacaagctc acagaacgac agcacaaagt cggatttcag
    22981 ggccagcggg ttatcgtcct ccgaataatt caggttgatg tccagcgggt tcacaaagtc
    23041 cttgctggta ggcgacagcc ggattacctg tccgtggagc cgtttgacaa gggggtaata
    23101 ttcggcctcc gggtctgaaa taaaaatatc gtcaggcgtc gttaagaaca cactgacgat
    23161 ctcggattta cagctcatgg atttgccgct gccgggggtg ccgagcttca aggcattggg
    23221 gcaacgggcc tgcttcctgt ccagcataat catgttgcgg gacttggcgt tgatgccgta
    23281 atacatggcc gcgccgccct gaaaaagctc ctgcgtcaca aaggggacga acacggccac
    23341 gctggaagtc gtaaggctgc gctgtatctt gatctgattg acgcccagcg gcaggctgct
    23401 tgcaaggccc tgttcctgct ggtagtccag ccggacaagg ggacagttat gcttttgggc
    23461 cacgcctgcg gcttggaaca cgtcgttatt cagcttttgc ttggtgtcgg ccacgttgag
    23521 gacaaggaac gtcaactgga acagccgttc attgcgggtc tgcaactttg tcagcagctt
    23581 cttggcgtcc tcgccgtagg tggcaaggtc gctgggaaga atgtccatat cgtaaccgct
    23641 gcggacggcc tttttctgct ccgcaatctt catagcgtca aggtcggtaa ttttgcgctt
    23701 gatggtcttg atcgccttgg tctgttcaat ggcctgcaca tggagattga ctaaaacacc
    23761 gctttccgta ttgaggaagt cggccagcat atcgtccgac agctccgggg acaggatttg
    23821 caggaaactt accgcgccgt atttgccgcc catgccgaat gtctttgcat tgccgaagca
    23881 cagggaggac ggggcaataa aatccttggt ggagaggccg gacggggcca gccacttcca
    23941 gtcaaaattg aatatctcgc cgtccgggtg gtacacgcca tgcagcaggt tcagccgttc
    24001 ccagccgtcc atcacatggg ctacggcccc catgctcttg aaatagccta acaggtcaaa
    24061 gccgatgcgc ttcaatctgg ctcgcgccgc tttcacgctt tcggcctcga tggtgaatgt
    24121 caggtatttg gtctttacca tgccgttgtt gccgtttgca agctgctttt gcagaatgcc
    24181 ggtgtactcg gcccggatgt cgtcgaagtc gtccccctgc ggcgcgatct caaagctctt
    24241 ggcgtactgc accgggtcaa ctttccgatt gaggaaagaa aactggatat gaatggaggc
    24301 gtccacatag ttatacaggt cgcacagttt ttcaaagata gccgtctgcg tgtccggctg
    24361 ggcaagctga tagctgatgt ccgcaaactc aatgcacttg gaaaagacgc cgggcgatac
    24421 ccggcacacg ccgtccgggt acatgacctc gtaggggatg ctctgctgcg ccgtgtgggg
    24481 cctgccgtcg cccttatatt tacggattac cgcgtcaatt tcttttcgct gggcgcgggt
    24541 cagctttgtt ttttcggttt ctcttgggat ttcctttttg gacaatggcc tttacctcct
    24601 gttccatctg gtattgccgc acaagggcgg tgtaggtgtt gtcggtctga tagggacgct
    24661 cctttggctg gatgaagcag cactggatga tctgcataat caccacttca aggggctggc
    24721 cgtgacgctc gtacatggca agcaaaaagc ccggcagcat ggcaaatacc atgagcaggg
    24781 ccgccgcgct gttggtaaga tagtcacggg tgagaaaata taaggggacg ccgatcacca
    24841 gcgccccgga aaaacagatc agttgccgtt tggtaagccc aaacacaacc ttgcttttca
    24901 catgggttaa gtccttgggg acggttacat aagccatttg gcacctcctt tcacgtcagg
    24961 ataaggtcac attccacctc gttcccccac acgtcccagc cgggggtttt ctgtctggca
    25021 aacagctcca cgcggggcaa atcgcccgcc agctctacga ttttttcacg ggtcacatcc
    25081 ggctttttgc tgtgttgttc aatcgggctg ataataaact gatggacaga ggcagaacga
    25141 cgcttcggct tgccgtgtgt tgccagcagg cagatttccg cgtttcccct tgtccagcgg
    25201 cccagcccgt aaaaccatgt aaggctttta cggttctgtt tcagccatac aaaagccacg
    25261 gtcttgaatg aaaagcccca cgctttgatt aaccgcagag cttccggcag catggggaat
    25321 gtggcccaca aaaacagcag gcagtctttg gacgccagcc gttccaccgg cagggcgcac
    25381 agctcgtcaa tgctcatggt ggaatagtga ttttccgctg cgccctgtac gtttttgcag
    25441 tcataccgcc acggcgggtc agcgtaaatg atgttgtacg ttgaaataag caagttcctc
    25501 ctgtgtatgc ttggattttg ggatcaatgc gccccgaata cggcctttga tatactgccg
    25561 gtcttgaaca ggcagaagca cagcagcacc gtatagccca tacagcccca gattgcgccg
    25621 gatatgtcgg aagcggaacc gatattctgt atcagcaccg cgtagatacc caccacaacc
    25681 atgattaaaa aggcttggaa gcccagcgcc agcagggatt tcagataccc ttggcccatg
    25741 ccgcgccatt ccgcgttgcc cattgtggca agggggatag gccccagcga cgtgacaaca
    25801 tagatttcca ccatgcggcc ataggtcaca aggaaaatgc agatggaaag gatattcatg
    25861 gtgaggccca caacaagggt ttggaaccac agccccaaaa gagcgcccac gctcatagcc
    25921 tccaattggc tttcaaggtc tggtatcagg gtgttaaaat caatggatgt ctgcccgata
    25981 atcacaccgg cgctttgatt gacgacgctt tgggtggcgt cgaatacgcc catgacgatg
    26041 ttccatgtgt tcgttacgat caggattgca aacgcggatt tgaatatcca gcggaagaac
    26101 atggagctgt caaagtcgtg catattgttc ttttccgtta tcatctggat aagctcatag
    26161 cacatgacaa gggcgagtat ggccccggct atggggacga tcacggtttc cgacaggctg
    26221 tgcagcatat tgaaaatacc gctgttccat gcctgcgggg ttcgtcccac gtcggcggcg
    26281 atttctccga ctttggcatt taccgtatcg aacagcccgg acaggttgcc cgtgataccg
    26341 tccatgagga tgccttttat ccattcttca atgatttcac taatcacggg tagcacctcc
    26401 tttcccgcgc cctcccggtc tggccgggag gacgcggagg cgattagtta agggtttgga
    26461 cagggacaaa ggccaggatc agcccagcag cccggacagc aggggaacca gagtgacacc
    26521 gatcagggcc acgccgccgc cagcgacaag ctgcttgaca ccctgcgatt ttgcccccgg
    26581 attgtcctgc ccgtatccct ccaacagatt gatgccgccc catacgcaca gagcgccgcc
    26641 cagtccgatc acgatagtct gcaaagtagt aactgcggaa ttaaaaaatg ccataaattt
    26701 acctctttct gccggtttcc ggctcataat gattttttga ttttgttgtt ggaatgaaaa
    26761 aagccgctgt ttattcagcg gcggcgtcct cgtccgacag gtcgatttca tacaggtcga
    26821 atacttcatc ctgcgttacc acttgctgcc gtttccggcg cgtgatagtc aaaaatctgt
    26881 ccacgtcaaa ggtattcttc ttgtcggcgt cggcaaggta tttgtaccgg ggatgcttgg
    26941 taatatcgaa tttctccgat aaaaacgggc gcacaccccg tagctgcaag atacacttgc
    27001 cgccgtccat cacggcaatt tcgtcttggg acatcaactc ctttcctaat ttttgatagt
    27061 tcaatccgtg ggacgtttgg cttccccggt tctcgctggt gttgaaactg tcaatcgttt
    27121 ctttccccag cgcatcggaa atctccttgg catttttgcc gcgcccacta aggaaaagca
    27181 cactatcgca gttatccgaa atgatctcgg cggcgtcctt gtaaatcgct tttagctgcg
    27241 actggctctg caaaataata gaggccgata tttcacggct tcgaatggtg gcaatgagtt
    27301 tatcgaaatt gggtatttgg ccaatgttgg caaattcatc caaaatcagg cgtacatgga
    27361 caggcagccg cccgccgtac acatcatcag cccggtcaca aagcaggttg attagctggc
    27421 tttggagcat agccagaatg aaattaaagg tcgtgtccgt atcgctcata atgagataca
    27481 gcaccgtctt ttcgtccccg atggtgtcca gctccatttc gtcgtcctcc atcagctcgc
    27541 gtacctcccg gatgtcaaag ggcgcaagtc tggcaccgca tgaaatcagg atggaagaac
    27601 gggtcttgcc tgcggacagc aggaatttct tgtactggcg caccgcaaaa tggtcggggt
    27661 ctttctgctc caaacgctca aacatgagat cgacggggct ttgaaactcc gggtcgtcct
    27721 cgcgggcttc actggcgttt atcatttcca gcagcgttga gaagttcatt tcctccgctg
    27781 gggcctcgta ccagatatag ccgatcaggg ccgaataaaa caaccgttcc gacttcaccc
    27841 aaaaatcctc cgctgacttt tccccctcgc ccttggtgtt ggaaatcagg gtatttacca
    27901 gctttagcac gtccttttcc gaatggatgt agacaaaggg gttgtacttc atggacttgg
    27961 aaaagttaat ggtattcagg attttaatgc ggtagcccgc ctgctggaac atcctgccgg
    28021 tttccagaac caaagtgcct ttcggatctg tcaccacaaa cgaagtcgga tagtccgtgg
    28081 tcggaaagca ttgcatcagg ttgggtttca cgaaaaatct cgttttccct gaaccgctgc
    28141 caccgatcac cagcacgttt ttattccgcg ctgtcttggg gtctttgggc ctgccggtca
    28201 tggtaagccg ttccgtttgg gtgagcagga tattattttc aaacttgggg tcgatgtaag
    28261 gcgctatgtc tttggccgtc ccccagcggg cgctgccata ctccatgcct ttgcggtatt
    28321 tcttcacgtt cttgctcttg cagtacacca ccagccgcac gatcacggca ccggcgatac
    28381 cgatacacag gtcaaacagg tgcaggcttg gcagcgggtt ggcaaaagcc gccgcaaaac
    28441 catccgcaaa atgcaggagc ttccccgaca ggtcagcacc agcggccagc cggtacgcct
    28501 ccccgcattt cgcaaacagg tacacaaaaa tcagatacgg gaggttcagg atcagcaatt
    28561 tctttacgtc aggcttcaca gttccagccc cctttccttg attttctcct tggcccgctg
    28621 cttggtctgg gccgccgcct tttgcttcac agcggacaaa accttgcgga tagagggccg
    28681 ctgctccttg gaaagcgtct tggcggtaaa ctcccgaaac gccagatcaa ggttatctgc
    28741 atccttggcc ttgaaaatca caacgtagtg gggcggctgg gtggtcttat cttttcgtaa
    28801 ggtaaaatcc acgccgtatt tcttggcgca tggcttgaac gctccaatgt tggcctcggt
    28861 gatctcaatg ttggagagat cagccccatg ctttttaagc tgctttaggc tctgctggcc
    28921 gtggtgcagc gtgtttttgc ccttggcccg gtgttgcagg tactttttca gcgccgcttg
    28981 cagcacttga gccgtgagct tgcccgtttt catggacagg gcaatggtct tttgagtaac
    29041 ttcttcctgc aatcgcatcc ctccttgtca gaaagtcaaa agcggcgtct aaggcggaac
    29101 caccagacgc cgcaggtaga tataggtcaa atccgcaccc gcaggccgga aaggtcgtcg
    29161 gcccggatgc cgacaagata ccagttttcg gccatttcaa tgcgggtggg cctccatttg
    29221 ccgccgatca tcacgtcgaa acactccccg caatgcaggc cgccgtaata gtcggccaga
    29281 tcaaagcgga tgtcgtaacg gtctgttcgc tcgtcaaaaa tcaatgcgcc ctgcttcata
    29341 gggtcgtcct ccttttctcg ttacaggctt tcgccctcgc cgcaggaata gtccggcagg
    29401 ccggatttag gctttcccca atcgggctgt gccatgtcgt gcgcgacaag ggccgtgtag
    29461 tagttggaaa tggtgctggg ggcgttgaac agcatagccc gcaggtattg tttgatattg
    29521 cggactttcg ttgtgttctc ccgcagacag tcaaggacaa agcggatatg ttcgccggtc
    29581 agcttcatgt acttggattt caccagctcg gcagggtagt cgtccccggc gacacggatt
    29641 gtctttcggg cggtgcagac ggtttccagc atcaggtcta cgatttcgtc aagctgttca
    29701 cggtcaatgc tcctgtcctg aatgagatag gcatactcga tgttctccaa aatgatttcc
    29761 cgataaatcc gtacagcctc atcctttcct gtccttttcc gttccggcgg cgtagccgct
    29821 gcctcgccct ccataggggc aggggtcggg gatgggatag gaatggaatg ggtactttgt
    29881 ccatctgtaa ttattttttc tttttttgat aagtcagttc tttgtacttc tttatttaat
    29941 tgcgttggat tttccgacgc cggattatcc gatgtcggat tttccaacac cgggttatcc
    30001 gatgttggat tttccaatac cgggttttcc aataccggct gttcgtagat ggtatagacc
    30061 atatcggcca ttttgccttt tgcgtcacgg ccctgctcac gccggatata tccagctttt
    30121 tcaagctccc ataccgctgt cctgatcgcg tcgatgcttt cccggttgat ataggacagt
    30181 ccttttaggg tatagtccca atcctccggc aaggacaaca tctgcgacag caggcccttg
    30241 gcctttaagg tcaggttctt attccgcagg tggtgatttg acatcaccgt atagcctttg
    30301 ttcttttcca cacggaaaac tgccatagcg ttgttcgctc ctttcactgt gaatttgacc
    30361 gctgcatagt cggtcagctt gcccggctga tagggacact ctgcaaactg gcagaattga
    30421 tatttccaat ccgggcggta aaatcggcag gtgccgcaat cctccggcgc gtccgccccg
    30481 ccgccgtcgt agtgatcgaa accgggcttt tcctgcatca gccgttcaaa cgcccggtca
    30541 gggccggaag taaatagcat ggcgtcgcct cctttctcta tttgggcata aaaaagcggc
    30601 gtcctgttct cccatgacgg gaaagaggaa cgccgcgttt acggtgtcgt attcaattta
    30661 tgatgtgccg tatttggggt ggcgggtatt agcagtatgg ttcagcatat atgcggctca
    30721 atccgaaagt agtaaattgg tagtaaattg agttctcata tcctgcgaaa tgcccgtatt
    30781 tccggggctt tcagcgataa cctaaatttt tggaataaaa ctttcattat aggctactgc
    30841 aacatccatc caatcagcaa tctctttttg gatctcaggt cgtttccagt agccaacgac
    30901 gattttattt tgtttattta atcgagcatt gatgaaccca tattcgcggt caccatgagc
    30961 ggattgattt aaattcatga aatccatatc gatcgttttc caaggaatgc tttcgttata
    31021 ttgcgtagct aaatgaagca atggtttttg tagaagcttt gtcccgcgga tccacatttt
    31081 tgctggtgag aaagtatgca tccaagtgat cacacctgct acttcttctc gataattgac
    31141 ctctttcatg atttttgtga tcgtatcagc agtaactgct aattcttgaa ggcggattgg
    31201 ataaggcaat tggccatttt cattcagttc atcgaccatt tcttgtgcat gtttctttac
    31261 ttctcgcagt gcttcttccc catataaatg ctgtgatcct acaacaaacc aaaattcttt
    31321 ttctccaata ttcaacataa ttagccactc cttttatttg ttttgtccgt aatacgcatt
    31381 ttttccgtgt tttcgtaaat aatgtttatc taaaatccgt tgaggcagct cttctgaaaa
    31441 tgaattgagc tgtctggtaa ataaattcat cttgcatact tcatctagta cgactgcgtt
    31501 cattaccgca ctttgcgcat ctttccccca agtaaatgga ccgtgtccgt gtaaaagtac
    31561 ccctggaatt gctaagggat caattttgcg ttctttgaat gtttctatga taacttttcc
    31621 tgtttcatat tcgtacccgc tgtcgatttc ctgttgtgtc aaaaatcgag cacaaggtac
    31681 cgatccataa aaagtatctg catgcgtcgt ccccatcgca ggaacatcca atcctgcttg
    31741 tgcccagatc gtcgcccatg tcgagtgagt atggacgatt cctccgattt gaggaaatga
    31801 acgatataaa acagcatgag taggcgtatc cgaagaggga ttgagtttac cttcaatgat
    31861 atgattgtcc aagtccacaa cgaccatgtc gtctgctgtc atctcttcat aactgactcc
    31921 gctaggtttg ataacgaaat atcgtgtttc aggatcaaaa gcgctcacat ttccccatgt
    31981 atatttgacg agtccgtgtt taggcaagtc aagatttgct tggtatactt cttctttcag
    32041 ttgttccagc attttctatc actccttttt cttgcaattg atgaatcgct gttttttcaa
    32101 tgtcgatccc ctcacggtaa cgtctcataa atatctgata gcctgctatt tcttctgctg
    32161 aaggtgtgat ggtgattcct tggtcttgtc caaacacgtc ttctgccaag aagttttcta
    32221 aagacttccc atgtcgatcc atcatatagg ctgctaataa cgcgattccc cacgctccac
    32281 cttctccggc tgtgtccatc actgtaactg gtgcctccat agcagatgct agaatccgct
    32341 gtccaacttc tggtgtttta aaaatccccc catgccccac taaacgatca atttggacat
    32401 tctcagattt caatatatcc attccgattc tcattgcacc aaaagcactg gctaaatgga
    32461 tccgcatgaa attcgctaaa tcaaaacggc tacctggtgt acgtacaaat aatggccttc
    32521 cttcatttac tcctgtaatg ttttcaccgg aaaaataacc ataagaaagt aatcccccgc
    32581 aatccgtatc gccttctagc gctttgttga ataataccgt gaataattta tctctgctta
    32641 tctccatacc caaagaattg gtaaattctt caaaaatact gacccaagca ttgatatccg
    32701 aagagcagtt attcgtatga accatgccta ctagttctcc tgaaggtgta gtgaccatgt
    32761 cgatttccgg atggacattt tctagttctt tttctaatac gatcatagcg aaggcggaag
    32821 taccagccga aatgttccct gtccgtttgg ctacactgtt cgtagcgacc ataccggttc
    32881 ctgcatcccc ttctggcgga caaaccggga ttcctggtct caaatttccc gtagggtcga
    32941 tcagataagc ccctgattcg cttaacttgc cagcttcttc tcctgctact agaactttag
    33001 gcaaaatgtg atccaagtca atcgctacgt gcgctttttc gattaactga ccaaaaatat
    33061 ttttcatttc ttgatggtag gttttcgttg aaggatcgat aggaaacatg cctgatgcat
    33121 ctcctacgcc tagtactttc tcaccagtaa gctgccaatg gacataacct gcaagcgttg
    33181 tcaaaaaatt aatttctttc acatgttctt ctttattcaa aatagattga tacaaatgag
    33241 cgatactcca tctctgcgga atattgtatt gaaatttttc cgttaatatt cgttctgctt
    33301 cttcagtgat tgtatttcgc caagtacgaa atggtactag taactgttcc ttgctatcaa
    33361 atgctagata accgtgcatc attgcactga acccaatcga cccgattgtc gtaagattct
    33421 cgccatagat ttcgaatact tctgctgcca tttttcggta actgacgcgc agtcctttcc
    33481 aaatatcttc taatgaatag gtccagatac cattttctag tttgttttcc cactcataac
    33541 taccagcggc aataggagta aaagatgaat caatcaatac agctttgatc ctagttgatc
    33601 caaactcaat ccctaaagat gtacgaccat ctatgacatc taacatactt tgcgcattta
    33661 cttccttcat aatgatttaa ctccctcctt ctcgtcaaac ctgatcaaac cgtcttttta
    33721 gtagcgctta caatgattat tgtatacttt tgtacgtaca tgtcaagcgg ttatttacaa
    33781 gaatacaata aaaaacactt gttttgtacg tacataagtt ataaaatgaa attgcttaca
    33841 aaatctgatc aaccgccttc tcgaaattct agaaggagag aatacttatg aaaaaagaaa
    33901 aaaaagtttc ctcatcgttt atttattttt ttggcgcatt tggcggcatt ctatttggat
    33961 atgatattgg tgttatgacc ggcgccttac cttttttaca gcatgattgg ggtttggcag
    34021 gtaaagcttc tttgatagga tggatcacgt cttcggtcat gttaggtgcg atccttggcg
    34081 gctctttatc tggtcttctt tctgataagc ttggacgacg aaaaatgatt cttctttctg
    34141 cacttatttt tatggctggt tctgtccttt ctgcatctgc ccctcacaat ggttcttatt
    34201 ttctgattgc agcaaggatt cttctaggtt tagctgttgg cgctgcatct gccctagttc
    34261 ctgcttatat gtctgaaatg gctcctgcta gactaagggg aagattgtca gggatcaatc
    34321 aagtgatgat tgcttctggc atgctccttt cctatgttgc agattatttg ctaaaagtgt
    34381 tgcctgaaac gatggcttgg cgcgtgatgt tagggctcgc tgctgtcccc gcgctgattt
    34441 tatttttcgg tgttttagct ctaccagagt caccgcgttt tcttatgcaa tctggccgct
    34501 tggaagaggc aaaaagagta ttgaactata ttcggacacc aaaagaagct gaacaggaat
    34561 tcgaacaaat ccagctgaat gtcaaacaag aaaagacaac cggaacttct tggcatactt
    34621 tgtttttaga aaaatatcgt tccttagtca ttgccggtat tggtgtagca gtattccagc
    34681 aatttcaagg agctaatgct attttttact atattccgct gatcgtagaa aaagcgactg
    34741 ggcatgcagc gagcgatgca ttgatgtggc cgatcatcca aggaatcatt ttagttgctg
    34801 gttctttgct ctttttggtt attgcagaca agttcaatcg gcgaacttta ttgaaaatag
    34861 gcggtagcgt gatgggactt tcattcatcc taccagctgt tttaggaact gtactggatg
    34921 ctcatacaaa ttcgttgttg attctcttgt ttttatgtat ttatgtcgca ttttattctt
    34981 gcacatgggc tccactgaca tgggtaatca taggcgaaat attcccacta gctgtccgcg
    35041 ggcgagcatc tggcctagcc tcttctttta attggattgg ttctttccta gttggcttgc
    35101 tttttcctgt gatgactgct tctatgtctc aagaaatcgt tttcggcatt tttgggatca
    35161 tctgcttttt aggggtttta tttattcaag agatcgtacc agaaactcgt gggaaatctt
    35221 tagaggaaat cgaacaaagt gcatctaaaa aaacttatcc taaacgtatt tctatccatc
    35281 attcttaaag aggttgtgac agaagtggtc agcttcaaga aataagaagg aaccgcttag
    35341 tttccagtca caaggaacaa tttcaaaaaa cagcttctca tgtttgatga atattgtgac
    35401 ttgtgaccag ttggtaggag aacaccgttt agtggagagg tggtgaaaga aacgttcagc
    35461 cttgagcgat gacaaaagct ctcacaaaca ttgcgacgag taaccgtagg agcaataaga
    35521 ggcggtaaaa acccgtctct tatttttcgt tttctttcac tgtttcccgt tcaactagta
    35581 caggttcata gagaatattt ggctgtgcct gtcctttttc aatcgttgtg acgatccacc
    35641 gtgcggcatc ttgtcccaac ttttcttttg gatgcgtcaa tgttgtcaat tttttattcc
    35701 ctaaatggct taaagaagaa tcgtctgttc ctacgatcga taggtcatct ggaatatgat
    35761 agccattttc tgtcaactta tctagcatta aactagctat ttgatcgtta tagcaaatga
    35821 tgccatctaa agcttgttct tctttcaacc gttgtactgt tttttcagcg attgtttctc
    35881 gtgtttccgt ggtgaaagta atgatatctt ccgtcaaaaa acgcacatta tactgttcac
    35941 acgcgctgat aaaacctttc atcctgtatt ttccttgaag atcgtcgatt tttgtgatga
    36001 acaacagacg ctgatgtcct ttttttatca aatattctgc tgccataaaa ccgactttca
    36061 catcatctaa acaaatataa gaggcattta actcttcata agcagcattg atcatcacca
    36121 tcggaatgcc ttgttctctc aaagcaacat aaagtgctaa gtttgggtta tactgattac
    36181 ttttcgtagg ctcaacgatc aaaccatcta ccccataagc aatcattttc ttcaaacact
    36241 ctttctccaa ttcgtgatcg ttattcgtac tggctaaaag caatgaatac ccagattctc
    36301 gtaattcatt ttcgattcct cggataatcg acggaaaaat ataatcagag agatatgtgg
    36361 tgatgacacc gatcgttttt gttctgttca atggtgtttt ttctttctta tagctgtcat
    36421 ctacatatgt gcccgaccct ttttctttac gcagatagcc ctcatttacc aacacagcga
    36481 ttgcttgccg aatcgtatgt ctgctgacgt catatatttc ttgcagcttg aattctgagg
    36541 gaatggttgt atttacttcg tattcctcac gaaggatctt ttgttttatc tcttctgcaa
    36601 tatcttgata ttttgccatt tgccttgccc ctttttattt gtacgtacat atatcataac
    36661 gagtctgcaa ggtttattca agcaaaaatc aaggtttctt gtgctcataa ggcatacgga
    36721 acaggttcac caaattctgg aaatccttgc tcattccacg taaagcattg cgcgttcgcg
    36781 tgccgattag gattgtctaa cggatcccct ttttggttct tctctggtcg agcatgatag
    36841 atcaaaatat caaagcaccc gtcttctgaa accgtaaacg agttgtgacc aggaccaaat
    36901 tgcttatttt tttcagaaga aacgaatact ggctccgata atttatgcca tgattctttt
    36961 aataaaagat tcttgtgctc atcagcccac agcaggccca tggcatagtt ttcatctgtt
    37021 gcactaccag aatacgtaat gaatattttc ccattgcgag taaggactgc tggaccttca
    37081 tttactgaaa aaccccgttt ttcccattca tactcaggta tagaaaggag gatctgcttc
    37141 ccctttaacg tccaaggatt atccatttcg gatagataaa gattagaatt cccagtaatt
    37201 tcaggatctt gttgggccca cacataatat agctttcctt gagaagagaa agttgttccg
    37261 tctaaactga aagtttccct tttcgttttt atttgtccct tttctatcca atctgtattc
    37321 attggatcta tatgctgatt ttcaagtacg aacatgcggt gatgatgaga ttcatcacgt
    37381 atagttttat gattgcttgc agcaaagtaa atataccatt ttccattgat ataatggact
    37441 tcaggtgccc agatcaattc actcatcggt ccttcttcat gagcctgcca tacaatcagg
    37501 cttgcagcat gttctaattc attcagtgac tttgcccttc ttaattcaat cacttggtag
    37561 cctggaaccg atcctgtaaa ataataataa ccatctgtat gtttatatac ccaaggatct
    37621 gcccgttgcc gaacgatagg attattataa agtgtcttca tcataacaaa tttcctcaca
    37681 ttttctttat tctaattaca ttccaagagt atttttctat ccctacattt aattcgtcat
    37741 gtttttctat tgaaaaatag tttatttcag gttttatttt ttctggttct tcacgtgtat
    37801 ttttgtccaa cagatcgcta ctggttaatg tgtagtgctc tccttgatct agcaaattga
    37861 aatcatgttc aatcgttatc ttttgttgtt catttgtgcg attgatcaag aaaatagtca
    37921 gctgattgcc gttatctacg atcacactgt ccacataagg aacatttttt atcttttcac
    37981 aatcataaac agggcaaatg atttgttgtt tcaatacttg acctttagca tatttcgata
    38041 agtgttgcat cacataataa gttggattcc tccatgcttg tcctttagca tctgtcagta
    38101 ttaaaggtat tgtgtttact aacaatgatt gacaactaat ctttacgcga tctgcgtgtc
    38161 gtaaaatagc cagccctaat gaaccaaata ataatgtatc ttccatagta aagtaacacc
    38221 aatcgatggg actaccgact tcaaaatccc tatgtctttt ttccggttgg gcatgtacat
    38281 tccattcatc aaacgctaga tacattgttt tctcacttct caaatatcct tttacataat
    38341 cacaagtagc aacgatttct tcaatttgac gatcgaatcg ataagctttt gcaaggtatg
    38401 tcgctgtatc atcacgctca tttttaggag gtttagtcaa gtcttcttca tcatacttat
    38461 caatatagtt atgcaaagct aaataatcta cattctcata agcttcttct aatgcgatac
    38521 gatcccattc agggtacgat ggtaaacgtg gcgtagagct tccaactaag attgtttcaa
    38581 ttgaatcatc cactaacttc atgacttttg aggcttcatt tgctaaccta ccatattcat
    38641 aagcactctt agcccccact tgccatggac cgtctagctc attccctaaa caccataatt
    38701 taacgccaaa aggctttttt tgcccatttt ttattcttaa atcactccag aaggttcctt
    38761 ttggaaaatt acaatattct actaaatttt ttgcttcatc aattcctttt gttcctaaat
    38821 tcaccgtgaa tatcggtttc gcttgtacat gactgatcca tttaaaaaat tcgtggagtc
    38881 caaaagaatt tggttctata cctcgccatg ctaaatcaat tttttttggt cgttgttctt
    38941 tcctacctac agtatccacc caatcataac cagatgtaaa gtttcctcca ggatagcgaa
    39001 tgacacctaa ttctaattcc tttacataag agaggacatc ttgtctaaac ccgtcaccat
    39061 cagctgtttc atggcccggt tcataaatcc ctgtatagac gacacttccc atatgctcaa
    39121 caaatgagcc aaacagccga gaactgatct ctcctaccgt aaaatcctct ctgattttta
    39181 ctttcacttc ttcgtccaac agctttccct acctttcatt tcctatagtc aagataatag
    39241 atacaagttt ccatacgcca ccagcaaaga taaaaataaa aggagggaaa agaaatatga
    39301 gcagtacaaa tcctaataac aatacgcaac aaagaatatt tctcaaaaaa tcaaaaaata
    39361 ctttccatgc actttgttca aaaatttgta aaaatgtgat atctttgttt tcagaaatca
    39421 catatatcca ggataaaaga aacatggaat aaataagtaa aactacatat ccactaattg
    39481 aaagtacgat tgtctgttct tctaataatt gattaacaag aaaataaata atgatcgtta
    39541 acagactaag gaacaagttc ttaccaaaat gttgctttat tccttgaaag aaaaaataaa
    39601 tgatatttcc tgatccctca cctttccatt gcgccattac ataaaaaaca gcacatgtag
    39661 caggcacgat agtaataaca ggcaaacaca cgattaccca gagaatacct aataagatgt
    39721 aatcagaaac cacaatcaac tgtccataaa atttagtctc aactattttc atcttcctca
    39781 ctctttcatt ccagacatag ctgttccttg aacaaaatat ttctgtgcaa aaatataaac
    39841 cactagtaat ggcagcattg aaataaccgt tccagccatt acaggtccat aaaaagaaat
    39901 gttctgccct gtaaataaag ctaaccctgc tggtaaagtt ctcatttttg aactacttgt
    39961 caatatcaat ggataaagca agtcattcca actattcatc agcgtgaaaa tccctaatga
    40021 taaaagagta ggtttgctca atggcaacat gattttcaaa aaaatattaa actcacttaa
    40081 tccatcaatg cgtgctgcct cttccaaaga atctggtaaa gtaataaaaa aggaacgcat
    40141 catgaagata ccaaatgcag ttgtcatacg aggaatgatc aaacctgcat aagtatcaag
    40201 catgccaagc aaattgactt caataaatag aggaatcatg aagacttgga atgggatcat
    40261 cattgtcagc aaaacgaaat agaacaaaac tgattttcct ttgaaacgca tacgagcaaa
    40321 tgcatacccc gcaagagaat caaagaatac agaagtgatc actgtccctc cagcaaaaat
    40381 cactgtattt ttgatgtaat ctaataaagg gatcgttgtc caaaccttaa tatagttatc
    40441 tagggtatag ctatctgcaa atattctagg cggaaatgag ataatgtctt tttcgtgttt
    40501 aaaagaagaa ataatcagcc acaaaaaagg aaacgcaata accaacaata taactagcat
    40561 actaatcgtt cgaatgattt ttttaccact aactgctttt cgactattca cagtaactgt
    40621 aatcgagctt tctggtgcca tacaggtttc cctcctattt catttgtttt tctttccgtg
    40681 acatgtacac attagtggag atagctatag ttgcaacaat gataaacaaa accgaagaca
    40741 gtgctgatgc atagcccaat tcataaggtg ctgtaaatcc tcgactgtaa atatattgaa
    40801 cagctgtttc tgtcttaaat tgtgggccac cagcggttgc aacatatact tggtcaaaca
    40861 cttgcatcga accaatcaga ttcgttaaaa tacaaaaacc taaggaggga acgatctgag
    40921 gtagcgtaat gttaaaaaac tgctgtcgat ttgttgcacc atccatttga gcagattcat
    40981 acaaagaggg agagattccc tgaatagcag tcaagagaat cgtcatagta acaccaaaat
    41041 tcttccaaac agtcatgatg gctaccgtcg gcatagcaag ggttggatcg cgaaaaaatt
    41101 gagggatcgg caagccgact tgtgaaaaca agtaaggaat cgcccctaca ttcggatcaa
    41161 gcaacataga aaaaataatc gcaattgacg tcaatgaaca aataactgga atgtaaaatg
    41221 tcgaacgaca aaaacgattg aatctggtat ttttagataa tgctactgct gctaataaac
    41281 caacgataat ttgtgttggc gtttcgagta cggtgaaata taaagaatga atcaacgaat
    41341 taactgctcg ttcatcacta aatatacgtg tgaaattttc aaaacttaca aaatttcttg
    41401 atgtaaagaa aatattcaaa tctgtaaaac taatagcaaa tgttcctaaa agcggtatga
    41461 cagtaaataa taataaaact aaaaaagatg gagttaaaaa caaatacgca gcacgatcag
    41521 gacgattcca atatttggtg aatccgttca tatagtccac ctcatctttc attttgataa
    41581 aatatacaat cttggtttaa acgaatctga ataagatatc cgaacaatcg ctgtgatttt
    41641 tgcaataaca cctatctgca aatactaggt cgatcattca gatatctgta tcttgccaac
    41701 agtctatcct gtataaagtt ctgtactatt tttgcagtaa ttgattgatg gcatcatctg
    41761 catcgttcat gagtgtctca ggatcttctc ctgctaataa tttttcaatc agtggattga
    41821 tgatatcgtt attgatcgca gagatttggg taaaacctgg taaatatggc tctgcatagt
    41881 ccatttgttt cgataattca gatacaatag gatcattttt tacttcttca tcttttgcta
    41941 ctgaatccaa gtaggcagga aaaccatttt cgatactcca ttttttacca atttcagttg
    42001 tattccaata tttcaaaaac tcatagacag cttctttttt attattatct gtacttgccg
    42061 gaatggcata tcctacgcca tctaaaatag ctgttttttt gtctgaatca ctcccttgtg
    42121 gtaaggtagt cacattataa tcaatctcgt ttgctttcaa tccgttattt aaccatggcc
    42181 cattgatttc aatggctagt tgaccagcat tcattaaatt gtccatttcg gcgccagaaa
    42241 tcgattctgg accagtcttg tctacatgga tcattttttg gatcgctttt aacgttttaa
    42301 ggttctcagg agacgcaaat tcagacttag tataatcatc gttcactaat ttaccgccat
    42361 ttgctaacat ccagttatat aacggtgcag ttccatcctt attgaagaca aaacctgata
    42421 catttttact actatcagtt aattttggtg ccatttctgt caattcttcc caagtagtag
    42481 gtggttgttc agtatctaat ccagcttgtt taaacaaatc attattccaa tacatataca
    42541 tgccttgtac ctgcatgggg acaaaatact gtttaccttc tacttcacct aattcaatag
    42601 ccgtttcttt aaaatcagat ttatctactc catcatattc ccagaaatcg tctaatggtt
    42661 gtaccgctcc gttttctaca tactgtgcaa aatctggata atttaatgca ataaagtcag
    42721 gtgctttttt agaagaaatc gctgtaggaa gtttttcatt caaattggcc caagtcatga
    42781 tatccatttc aattttgatg tttttatcat ttgttttatt aaattcatta acgatttctt
    42841 gcaatatttc accatcagat gcagtaaacc cattccaaaa agtcaaagtc acttctttat
    42901 cagaatcaga ttctgctgaa cttccgccac cgcaagctcc taaaatacct gttgcagcta
    42961 ccaacaaaga gccaattaac cattttttac ctttcatttt ttgttcctcc ttcatctgat
    43021 aaacgacatc tgaccacatt ccaagatagc ggtttcaata aacaattgat tttcccatct
    43081 tcagctttta catttgttga atgacttggt tttacttgtt cacttttagg aagattagtt
    43141 gcttttgtat caaatccact catttcagaa aaatcaatca ctccctctaa tgataattca
    43201 gacaagtgaa cagttagatt catttcttct tctccacggt taactgcaaa tatgacaagt
    43261 tctttgtcat ttattacggc tatactttct aaatacggca cttcttcaaa atcttccgtc
    43321 gcatagtttg ctgaacgaat ttgtgggctt aacacctctc cttgtccata cacagcagct
    43381 tgcataaatg gataatagat cgtctgtctc caagcttctc cgtttgtttc tgtcctgatt
    43441 ggtgcaataa cgtttaccaa ttgagcaaga caagcaatct ttactctatc tgcatgtttc
    43501 aataaagtga ttaatagaca gcctaatagt aatgcatctt caaaattata gttatcttct
    43561 agtaaaggag gagcaatctg ccaaggcgct gcttgctcat cttgttccgc tgaatgatac
    43621 caaatattcc attcatcaaa ggacaggttg atctgcttct tactatgttt cttcgccttg
    43681 actgtatcgc acatcgctgt cacttcagaa atgaaccgat ccatgtctaa ggaacgtgca
    43741 agataatgag aaagatcatt tttttggttg ccataatatt gatgcagaga caaataatct
    43801 atttgatcgt acgcttgatc aagaactgtt aactcccaat caccaaatgt aggcatttgc
    43861 cgattcgaac ttccgcataa aaccacctca attgaatcat ctacgagttt catcgcctta
    43921 gccgtttcct ctgctaaccg tccatattct tccgctgttt tatgtccaat ctgccaagga
    43981 ccgtccattt cattccctaa acaccatgtc ttaattccaa aagggctctc ttgaccattc
    44041 gaacgcctta aatcactcca ataagttcct ttaggaaaat tacaatattc gactaaatta
    44101 cgagctgcat ctactccacg agtacccaga ttgacagcca tattgatttc ggcccccaca
    44161 tgctgacacc agttataaaa ttcatgaatc ccaacttcat tcgtttcaat tgtccgccaa
    44221 gctaaatcca accttctagg tctatttgct atgggcccaa tactgtcttc ccaacgaaat
    44281 cctgacacaa aatttccacc aggatatcta atcatgggaa tgttcaattc ttttaccaag
    44341 tgaatgacgt cttggcgaaa tccactttta ttagctgatg gatgatctgg ctgataaatc
    44401 ccttcatata ctgctcgtcc catatgttca ataaatgaac tgtacaaccg cggatcaact
    44461 ttgcctacac gcttgacact actaatcaac attgtggctt ccataactga cctcctttaa
    44521 tttatacatg aataatacac ctcgttgaaa gcgttgtcaa taatataaat gttaaactta
    44581 cttatttttt atcgatttta attaaccaaa atattaataa tgattaaaac aaataattta
    44641 atataacttt tattaacaaa tatgttaata tataagaaaa accttttaag aggtgatata
    44701 tatgcaacta caaataaacg aagaatcctt accggtatat gaagcattag ctagtaaaac
    44761 aaggatcaag atcatccagc tactttccaa aaaaaagatg aatgtcaaag atttggcaaa
    44821 agaacttgga gtgagcagtg ctatcacgac gatgcacgtg aaaaagctag aggaagcaaa
    44881 catcatcaaa acagaaaaag taggacaaca aaaaatttcg agccttcgtg tcgataaaat
    44941 cgatattagt tttccagaaa aaatattcaa tgcttttgat acgaaagaaa catcgatacc
    45001 tattggtcac tatacaaatt atgcaattga accaacatgc ggtttagcta cgatccatga
    45061 ttttatcggg aaagtggatg aaccacgcta ttttatggat cctcgaagga tggatgcccg
    45121 cattctctgg tttaccagcg gatttgtcga gtatcaggca cctaattttt taaatacaga
    45181 ggatacattg gagatgttgg aagtttctgt ggaaatttct tctgaatttc ctttttcaaa
    45241 tgacaattgg ccttcagata tcactttcag cctaaatggt gtggagctag gaacatggac
    45301 gagccctgga gattttgctg atatccgcgg taaatatacg cctgattggt atccagataa
    45361 tcttaatcaa tacggcttgc tgaagacgat ccgaattacc aaacacttga cgaatatgaa
    45421 tggagaaccc ttgtcaaaca tcacgatcaa cgacatccct aaagagcaag acacttggca
    45481 tttgcgaatc gaagtgaaag acgatgccaa acatgtgggg ggctgtactt tatttggtaa
    45541 aggattcggt aattacgatc aggatatcaa attaaaagtt tactacagct gatatttttc
    45601 ttttctattt tataaaacaa aaacagccaa tccctatgaa gggacggctg tttttgcttt
    45661 attgttattt ccagaaatca tccaaaacgg aaattggcaa atgtcgttta tgttgtgtct
    45721 tgttccacca tgcttcgatt ttttcttgtg cttgagcggg aacttctttt ccttctagat
    45781 aatcatcaat ttcattatat gtgacaccta gtgcgacttc atctgcaatc attggtttcc
    45841 catcttcaag atctgcagtc ggaatttttg tgtataattt ttccggtgca ttcaatgctt
    45901 gaagcaattg tttcccttgt cgtttgtcca aacggaataa tggcaaaatg tcggctccac
    45961 catcaccaaa tttcgtgaag aatccagtaa tgttttctgc agcatgatct gtccctaata
    46021 cggctcctgc tctttctcca gctacggcat attgcgtaat catacgttga cgtgctttga
    46081 tatttccttt gttaaaatcg ctgattccca cacctgcttc gcttaatact tgtacttgtg
    46141 catcaacagc tggtttgata tttactcgca gactaacatc gggctggata aagtcaagag
    46201 cagcttttgc atcttcttca tctgcttgtt caccataagg aagacgaaca gcgataaatt
    46261 gatagttttc atcttttgtt tcttcacgca tttcttccat cgttagttgc gccaaacggc
    46321 ctgctaaagt agaatcttgg ccgccgctga tacctagtac aaaagtttta agaaacggat
    46381 attttttcaa atatgctttc ataaagtcaa tacttttacg tatttcttct tttggatcaa
    46441 ttgttggttt gacacctaat tcattgataa tttctgtctg caggctcatt tattctcctc
    46501 ctatgcttct gtatgaagtt ctgctacgct ttttttcatt cgttccatga tagccatttt
    46561 atggttccag cattcagtag acagatcgac tgggtatttt tgcggattca agtctcgttt
    46621 atactcttcc catagtgaat ctagattttc ttttgtatat tctttgattt cgtttagtgc
    46681 aggtaattcg taaactcttt ttccttcgat aaagatatct tgtaaaactg ggcgagctgt
    46741 aaagtctcga acagttttat tgataaacgt atgcactgga tggaacatga agatagcttc
    46801 ttcttctcga gggtcttcat cccataatgt cacgtagtct ccttcagatt tcccatcaaa
    46861 atttcgagtg atgcgccaca cttgtttttt ccctggagta gttacttttt ctgcattgct
    46921 tgataacttg atcgtatcca tcatttttcc ttcatcatct tcgatcgata ctagcttgaa
    46981 tactgcacca agggctggct gatcataggc tgtgatcaat tttgtcccaa caccccatac
    47041 atcaatttta gctttttgca tctttaaatt caaaatcgtt gcttcatcca agtcattcga
    47101 agcatagatt tttgcttccg taaatccggc tgcatctaat tgttcccgaa cacgcttaga
    47161 tatataggcc atatctccac tgtcgatgcg tacgccttgg aagttgattt tgtcacctaa
    47221 ttctttcgcc acgcgaatcg cacttggcac acctgatttc aacgtatcat aagtgtcgac
    47281 taagaacacg cagtctttat gggttttagc gtaggccata aatgcttcat aatcatttcc
    47341 ataagattgg actaacgaat gagcatgggt cccgctagct ggtatcccaa atatcttccc
    47401 agcacgtaca ttgcttgttg catctgctcc gccgatatat gccgctctag ttccccagac
    47461 tgctgcatcc agttcttgtg cccgtctagt tccaaattcc aatagtggat cttctccgat
    47521 gacagatttg atacgagctg cttttgtcgc gatcaacgtt tggaaattga ccatattcaa
    47581 cagtgctgtt tctactaatt ggcagtgcgc taaaggccct tccacttgga tcaatggttc
    47641 atttgcaaaa actagttctc cttcacgagc agaacgaact gttgctttaa attcaaaatt
    47701 ttgtaaatac tccaaaaaac cttcaggata gacttctaat ccacgcaagt aagcaatatc
    47761 ggaatcattg aacgtcagat tctctaaata attgactaac cgttccaatc ctgcaaaaac
    47821 cgcgtatccg tggttaaaag gcatttctcg aaagtaacat tcaaaaacag catgtaaatc
    47881 agctcgacct aattcccagt atgtctgcat catattgatt tgatatagat ccgtatgcag
    47941 cgtcaaactg tcgtctgggt aagtattatt catcttgtat tactcctctt ggcaagtttt
    48001 catttcctac ccattataac aaaaaaaatt aataggaaaa gaaatcttcc attttttctg
    48061 aaaaagcaca tgttttacgg atatttcttg ctaaaaatga actccatctg c
//
LOCUS       DAZUJR010000010        45790 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.010, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000010 DAZUJR010000000
VERSION     DAZUJR010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 45790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45790
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.010"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            259..1473
                     /locus_tag="ACG804_000545"
     CDS             259..1473
                     /locus_tag="ACG804_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008519 - ammonium channel activity
                     [Evidence IEA];
                     GO_process: GO:0072488 - ammonium transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HFS4831499.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            1504..2931
                     /locus_tag="ACG804_000546"
     CDS             1504..2931
                     /locus_tag="ACG804_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFS4831500.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            2954..3880
                     /gene="glsA"
                     /locus_tag="ACG804_000547"
     CDS             2954..3880
                     /gene="glsA"
                     /locus_tag="ACG804_000547"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HFS4831501.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            4088..5548
                     /locus_tag="ACG804_000548"
     CDS             4088..5548
                     /locus_tag="ACG804_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831502.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            5769..7532
                     /locus_tag="ACG804_000549"
     CDS             5769..7532
                     /locus_tag="ACG804_000549"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HFS4831503.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            7616..8074
                     /locus_tag="ACG804_000550"
     CDS             7616..8074
                     /locus_tag="ACG804_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HFS4831504.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            8183..8866
                     /locus_tag="ACG804_000551"
     CDS             8183..8866
                     /locus_tag="ACG804_000551"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HFS4831505.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            9013..9627
                     /locus_tag="ACG804_000552"
     CDS             9013..9627
                     /locus_tag="ACG804_000552"
                     /EC_number="1.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HFS4831506.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            9643..9849
                     /locus_tag="ACG804_000553"
     CDS             9643..9849
                     /locus_tag="ACG804_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831507.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     regulatory      10074..10240
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            10388..10945
                     /locus_tag="ACG804_000554"
                     /pseudo
     CDS             10388..10945
                     /locus_tag="ACG804_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
     gene            11003..13042
                     /locus_tag="ACG804_000555"
     CDS             11003..13042
                     /locus_tag="ACG804_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HFS4831508.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKIAFDSLGGKAASTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFKTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(13151..14302)
                     /locus_tag="ACG804_000556"
     CDS             complement(13151..14302)
                     /locus_tag="ACG804_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFS4831509.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(14456..14986)
                     /locus_tag="ACG804_000557"
     CDS             complement(14456..14986)
                     /locus_tag="ACG804_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HFS4831510.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(15085..15435)
                     /locus_tag="ACG804_000558"
     CDS             complement(15085..15435)
                     /locus_tag="ACG804_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HFS4831511.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(15592..17121)
                     /gene="ahpF"
                     /locus_tag="ACG804_000559"
     CDS             complement(15592..17121)
                     /gene="ahpF"
                     /locus_tag="ACG804_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008785 - alkyl hydroperoxide reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000302 - response to reactive oxygen
                     species [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HFS4831512.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(17131..17694)
                     /gene="ahpC"
                     /locus_tag="ACG804_000560"
     CDS             complement(17131..17694)
                     /gene="ahpC"
                     /locus_tag="ACG804_000560"
                     /EC_number="1.11.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0102039 - NADH-dependent peroxiredoxin
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="HFS4831513.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(17838..18500)
                     /locus_tag="ACG804_000561"
     CDS             complement(17838..18500)
                     /locus_tag="ACG804_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFS4831514.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            18684..20330
                     /locus_tag="ACG804_000562"
     CDS             18684..20330
                     /locus_tag="ACG804_000562"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HFS4831515.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAALLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPDMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDFQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            20321..21403
                     /gene="uxuA"
                     /locus_tag="ACG804_000563"
     CDS             20321..21403
                     /gene="uxuA"
                     /locus_tag="ACG804_000563"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFS4831516.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFELPGWEP
                     ERLAHIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLP
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNEYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(21511..23064)
                     /locus_tag="ACG804_000564"
     CDS             complement(21511..23064)
                     /locus_tag="ACG804_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4831517.1"
                     /translation="MQTQEAIKTFLLKKKSNTKLDIFLFLSEHRFFITTQYLADHFHM
                     SESNFLLYIKELEQDFERLNLTELHIDKQKPFLKLNFEGIDPAYCYYRLFGRYCNESV
                     SYQILTSLFSCQTNSIISLSQQTNYSASYLYTKMKKINAFLALYGLSISFSNNGRKSF
                     SGKEVQIQYAALDIYWNIFSSTATEFYDEDPQVVAFMMNTFFKKEVLDRLNSGMIDKL
                     YFLLKICKENFPATSVKDVQKEFTEYEYIDFFIDPSVDILRPNLPICREQRILVNILA
                     RLSITKIESEETSLEQYKLLKKANVPHVLYSREMVESFCTVFDLFIPEKEKILYSLAF
                     ARNKLYNGFLNFNQPNTPLPTFMLYQEHSVLKEVQTAIEQFYMDFREQNQHLLPVILE
                     KENVQWMVEDLVHLYDRYKKQPRIVIGVNYTRDFYISKDLIVKIEQIFSNESIKIQND
                     FMENCNIVISDCPLKQLPSHIKKIYILKGIITPEDWKKVIMRISEYIFELKEEALMDQ
                     SKKENQVTS"
     gene            23212..24447
                     /locus_tag="ACG804_000565"
     CDS             23212..24447
                     /locus_tag="ACG804_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HFS4831518.1"
                     /translation="MRYSTILISTFAALSLSLTINQTVHTEEIETAKWTETKWANVNR
                     ITFQDEFSSFNSGVAKLRKGQTATIKAKIDYSGDLAPILQSAVTFENVDPALSIGYDE
                     NTLTIQHKQAIFTFTVTLNQDLLKPALFTVKVSDGLPNDHHHLTPYSQRQTIEQDSAI
                     DSGGDLVEEPTDKPENENKPEVPPTENPDGEQKPEIEPGEEPDTETQPEPDNESKPEI
                     TPGEKPDVDPEEKPDVTPEPDTDSGNQTVPETNPDTDNETENPEKPEVAPEEKPDVTP
                     EPDTDSGNQTVPETNPDTDNETENPEKPEVDPEEKPDVTPEPDTDARDQGIPEKINKK
                     TIQEDGKKESKKSNLAILKINEEQLNKKSRIFDSAQSAETLKSSKDTTFAVLKRKINS
                     YQNPESHKTKLYCGAESFY"
     gene            24420..24500
                     /locus_tag="ACG804_000566"
     CDS             24420..24500
                     /locus_tag="ACG804_000566"
                     /inference="COORDINATES: protein motif:HMM:TIGR01167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831519.1"
                     /translation="MLWSGIILLSIATMLSAKRFKQNRSL"
     gene            complement(24626..25705)
                     /locus_tag="ACG804_000567"
     CDS             complement(24626..25705)
                     /locus_tag="ACG804_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFS4831520.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(25808..26248)
                     /locus_tag="ACG804_000568"
     CDS             complement(25808..26248)
                     /locus_tag="ACG804_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFS4831521.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(26305..26715)
                     /locus_tag="ACG804_000569"
     CDS             complement(26305..26715)
                     /locus_tag="ACG804_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HFS4831522.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(26895..27329)
                     /locus_tag="ACG804_000570"
     CDS             complement(26895..27329)
                     /locus_tag="ACG804_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFS4831523.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(27429..28277)
                     /locus_tag="ACG804_000571"
     CDS             complement(27429..28277)
                     /locus_tag="ACG804_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFS4831524.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            28666..30432
                     /locus_tag="ACG804_000572"
     CDS             28666..30432
                     /locus_tag="ACG804_000572"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HFS4831525.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            30534..31793
                     /locus_tag="ACG804_000573"
     CDS             30534..31793
                     /locus_tag="ACG804_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFS4831526.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            31940..33241
                     /locus_tag="ACG804_000574"
     CDS             31940..33241
                     /locus_tag="ACG804_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4831527.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            33244..34095
                     /locus_tag="ACG804_000575"
     CDS             33244..34095
                     /locus_tag="ACG804_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HFS4831528.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            34108..34923
                     /locus_tag="ACG804_000576"
     CDS             34108..34923
                     /locus_tag="ACG804_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HFS4831529.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            35074..36240
                     /locus_tag="ACG804_000577"
     CDS             35074..36240
                     /locus_tag="ACG804_000577"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFS4831530.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            36470..37117
                     /locus_tag="ACG804_000578"
     CDS             36470..37117
                     /locus_tag="ACG804_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFS4831531.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            37201..38145
                     /locus_tag="ACG804_000579"
     CDS             37201..38145
                     /locus_tag="ACG804_000579"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HFS4831532.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            38280..39731
                     /locus_tag="ACG804_000580"
     CDS             38280..39731
                     /locus_tag="ACG804_000580"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HFS4831533.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            39752..40588
                     /locus_tag="ACG804_000581"
     CDS             39752..40588
                     /locus_tag="ACG804_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFS4831534.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            40588..41247
                     /locus_tag="ACG804_000582"
     CDS             40588..41247
                     /locus_tag="ACG804_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFS4831535.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            41373..42062
                     /locus_tag="ACG804_000583"
     CDS             41373..42062
                     /locus_tag="ACG804_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831536.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            42068..43024
                     /locus_tag="ACG804_000584"
     CDS             42068..43024
                     /locus_tag="ACG804_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HFS4831537.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            43068..43580
                     /locus_tag="ACG804_000585"
     CDS             43068..43580
                     /locus_tag="ACG804_000585"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4831538.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(43836..44384)
                     /locus_tag="ACG804_000586"
     CDS             complement(43836..44384)
                     /locus_tag="ACG804_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFS4831539.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(44473..45654)
                     /locus_tag="ACG804_000587"
     CDS             complement(44473..45654)
                     /locus_tag="ACG804_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside transporter C-terminal
                     domain-containing protein"
                     /protein_id="HFS4831540.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGLGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
BASE COUNT        15374 a         8154 c         8850 g        13412 t
ORIGIN      
        1 ttttatatga agtattcttt attccttatg aaaaaatatc tttaaaaata aaaaaagacg
       61 aaaataaacg gttttctata aaaagaagac cgtttatttt ttgtctttat ttgtgtgaaa
      121 aacgaaaaag agcacaacac atcaagcttt tattaattgt ctgtctttta taaatgcaag
      181 tattaattca aaaaaacaga agaaaaaaac aactacactt tcttttatac tcgtaatcgt
      241 agaaaggagg cgaaaaaaat gaatacatta cctatcaata caggagatac agcattcatg
      301 attttatgta cagcaatggt ttgcctgatg actcctggtc tagctttttt ttacggcgga
      361 ttagcacgga agaataatat actaacgatc atgtctcaat cttttctctc cgttgggata
      421 acaacgatta tgtgggtatt tggtggattc ggattggcct ttggacggga tatcggcggt
      481 gttattggaa acccggcaga tttctttttg atgagacatg ttacaagctt ccccaacatg
      541 tttcatggtg caacgattcc atttttaatg ttctttcttt accaactgat gtttatcgtg
      601 attaccgttc ctttgatgac aggagctttt gcagggagat tgaatttaaa aggctatatt
      661 atacttgtta ttttttggaa tctgctgatt tatttccctg tttgccactg gatatggggt
      721 ggcggatttt tggatcagat gggatttaga gatttcgctg gtggagcagt catccacacg
      781 acagctggat tcggctcttt agcatgtatc ctcacacttg gtcaaagaaa gattccttta
      841 ggagaaagaa gtcagcatag cagtcttatg gcagctgcta tcggtacagg actgctttgg
      901 tttggctggt tcggttttaa ttccggtggt gcacttcgag cagatgaaca agcagtcaat
      961 gcatttggtt caacattcat cgctcttgca tttgcgatga ttacttggct gatcattgca
     1021 aaagtaaaag gaaatggctt tgattttgtc gacgtactaa caggatccgt tgctggattg
     1081 gcagccatta cgccttgtgc cggttatgta gaagcaaaaa gtgccatgct gattgggatc
     1141 attgcgggta tcgtctgtca tgctgctgtt gattttcgta aaaagaaaca atgggatgat
     1201 gcacttgatg tgtggggtgt tcatggcatg ggcggattca caggtacgat tctgataggg
     1261 atctttgcat ctaacagcca tttactaacg aatccaagca gctggtactt cttagggatt
     1321 caagtgattg gtgtcatcat tactgccgtg tatgcctatg tgctgacaac agtgatttta
     1381 aaatcggcga tgcactttac aacgatcact actacaaaag aagaacaaga agaaggattg
     1441 gactttttct tctttggcaa caaactcaat tgaaacaaat tcaaatagaa aagaggaaga
     1501 ttcatgcaac aaagcaaaac gaaaattcct gcaaaaaaat taacgttctt tggctttttg
     1561 gctatgacca tctcaatggt cgtttcatta tatgaatatc ccacattcgc gacctcaggc
     1621 ttcagcttag tatttttctt gttattaggc ggtttgctat ggtttatccc tgtggcattg
     1681 tgcgcagcag agatggcaac ggtgaaagga tgggaaaaag gcggtgtcta tacttgggtc
     1741 agtcgcacat tgggaaaacg attcggtttt gccgcaatct ttttccaatg gtttgagata
     1801 acagttggct acttgaccat gctgtatttc ttaactggtg cattatccta tgcaacgggt
     1861 attggtgcta tacaaaacaa taaatatctg aaattggcaa tcctattgat tattttctgg
     1921 gctattttac tctcacagtt aaaaggaacc aaatacactt cattgattgc tcggatcggt
     1981 tttgtagctg gtatcttgtt gccagcatta gtcttgtttg gcttagggat ccattatgtc
     2041 gcttcaggcg ctccactaca aacgatactg tctatgaaaa cattgattcc tgatttttcg
     2101 aaattgccta cgctggttgt ttttgtttcc tttattttag catatatggg cgtagaaaca
     2161 tctgccagtc atgcaaatga aatggaaaac cctaaaaagg attatccatt agcaatgttt
     2221 gtattggtta ttctggcaat cattttagat acttttggcg gattgaccgt cgctactaca
     2281 gtacctcaac atggtttgtc tcttaataca ggggtgattc aatcgttaga attcctatta
     2341 agacacattg atccaaatct tgcatggatt gcgaaaattc ttgcgattct tgtttgttta
     2401 ggtgtcatcg gagaaattgc ttcttgggta acctctcctt caaaagcact tcacgtagca
     2461 gcagaagaag gattacttcc tgaatatttt gcaaaagaaa acacacacgg tgttcctgct
     2521 catttgatga tcgcaaatgg gatcgttgca acaatctggg cagccgtctt tacattaagc
     2581 ggcgggggga ataatctttc atttcttgca gcgatgtcat tgactgttgt aatctacctg
     2641 atgttgtact ttatgttttt cgcgggctat ttgaagctgg tttttaaaga tgacagtctt
     2701 gaaagagcct atcaggttcc aggcggaaaa gttgtaaaag taatcgttgc ttgtttaggt
     2761 cttttgactt cactttttgc tttttgtatc tcatttgttc cacctgctag tatcgcagct
     2821 ggacagcatg ggatttatga aacgattctg attgtttctt atcttatcgt cttagttatt
     2881 ccatttacga tctacgcatg ccgtcataaa ttccagcatg cagaaaaata aaaaatgaaa
     2941 gctggttatt caaatggaag taaaagaatt agaacaattg attggaaaaa atttccacta
     3001 ttatcaaaca ggacaagtgg cggattacat tccagcatta gctgaagtgg atcccaaaca
     3061 attaggtatg gcgatttatg atttggatac aaaacaactg attgagggag gagacgccga
     3121 tgtgcgcttt gccatcgaaa gcatgtcaaa agttcccgta ttgttattag caatcaaaga
     3181 caacggaata gaaaaagtct ttcaaacaat caacacggaa ccaaccggtt ttgccttcaa
     3241 ttctatcatg aatatggaaa tcaatcatcg caaacatcca atgaatcctt ttgttaatgc
     3301 aggagcgatt gcaacaacct cgttgattgc cggtaaagat gcagatgaaa aatttgagcg
     3361 aatcttgtca tttatgaaag agatctgtga tgatcctaat atcacattga atgaagaaat
     3421 ctatcattct gaatcaagaa caggtgatat caatcgctct cttgcttact atatgaaagg
     3481 taatcaaatg atcgaaggag acgtaccgga gatactcgat gcttatttca gacaatgctc
     3541 cctcaatgtc accgctacag gcatagcaaa attagctgct gtgctggcaa ataaaggaat
     3601 tgctccttgg aatggcaaac aaatcattac tgaagaaagt gctacaatcg tcaaatcaat
     3661 tatgacaact gctggtttgt atgatgaatc aggagagttt tccgtccatg ttggtgtacc
     3721 tgcaaaaagc ggtgtaggcg gcgggttgat ggcagctgtg ccaaatcgtt acggcatagg
     3781 tgtcttcagc ccggcactag atccatttgg taacagcgca gctggtatcc aattgttgaa
     3841 agatgtagtc aaagaactag acgctgacat ctttgaataa ccattcttga aagaggctgg
     3901 ggtaaaagtc caaacggctc aaagctacct acaatgaggc tgaaattgtg agcttgtttg
     3961 acttttgtcc cagtttcttt ttttattggt ttttgaaagg gcttttctaa ataaaaagga
     4021 aacaaaaata cgatttacag atatgattaa ataaaatcat aagaaaaact ggaggcgtgt
     4081 atcaggaatg ctggaaaatt acatcgagcg aaatatattt agaaaagtgt atctgtgtga
     4141 acaattattt gaattccaag aaatagacat cgaacaaaca gctatttctc taagggtgac
     4201 tacaccaacg atccttcacg atctagaaag tctagccgag tgtctagaat attgtataaa
     4261 agaacaagta agagagaagc ataagtataa actcgtattc aaacatggta ttgctctttc
     4321 tgagctcaca cagtttctgt acggtcaatc ttatttttta aagtttttaa gttattattt
     4381 taatggtata ttcacgagta cagaactggc tgatcttgaa tttatttctt tgagcaaagt
     4441 atatacaatc aaaaaaatcg tattggattt ttttaaagaa aatgattatt tgaaaaataa
     4501 agaaatcatt atcccagaat ttgactcgcg gaacatcttg ctagctttag tacgttatgt
     4561 caattgggaa ggctatgaaa ataaaaatcc gtatgtagaa gaagcttgta acgagttgat
     4621 tgattatgta gagactcatt tttttaaaag aagatattcg gaagatgaaa agtcctttat
     4681 catacgagga atagagatcg caatcggaag aaaggcattt ccccttggac tgaaagaaga
     4741 agataagaaa agcgcagaaa cgaagccgtt atttcaatta gtctgtcaag gattggaaga
     4801 gcaaaaagga attctagact tacaagaaga agatgtctat tatatttttt ctttgttcaa
     4861 cagtagaaat tataccaatg agaacatgga gctgttaaga aaagatttcg aagttgttta
     4921 taaaaatttt gttctcaatg acctatcact gaatgaattg attttacaga ttattagtat
     4981 cgctgaaatc gacgatgcag aaaattttat tttcaagcaa tcctttttac aatttgtccg
     5041 tacgttgtgg gcagatggac aagtattttt accggaaagg atctatcttc tatcagaaaa
     5101 agaacaactt ctgtacggaa aaattgtaga aatattggaa gagtggaaaa agaaaaatca
     5161 aatccaacta agatggaatg aaaatttcat tcgaaaattc gtcaaaagtc tttctttgat
     5221 caacagtgaa caagcgggga gacaggaaat agaaattttt gttgtttcag aaagttcagt
     5281 caaacaattt ttttatcgaa cccaatttca tttgtatgcg gaagaaggca tcgctgaaat
     5341 aaatcctatt ttatttcgtt cattagaaga attgcctgat gaatgtctat gtgcgaaaaa
     5401 aagagtggtt ttgtgcgatg ctgctagcta tcaaaatgga ttagaaactg aaaagacaaa
     5461 gatctatcca atctcattaa aaggtgcaaa catccatttg tatcatattg ctcaggaact
     5521 tcacctatta aaaaaacata tttcttgatg agaccttaat taggagacct tctacaaagc
     5581 tttttaattg tctgtagaag gtttttattt gagtcctgat tcgtgcgaag atctacttat
     5641 ataacaagct ttctctgaaa tttttttaaa atgctattga cttagagtca actctaagta
     5701 gtagaataga taaagtgtaa caaatctatt ttcattaaaa gaagatagta cggaggagag
     5761 aatgtattat gagtacagta ttacatgtat tggatgcaat caatagcccc gcagatgtca
     5821 aaaaattatc tgttgaggaa atgaaacagt tggcagaaga gatgcgccaa aaaatcttgc
     5881 aaaaggacag cgatgtaggt gggcacgttg gtccgaatct aggtgtagta gaattaacga
     5941 ttgcgtttca ttatgtattt gattcaccaa aggataaaat cgtttgggat gtttcccatc
     6001 agtcttatgg tcataagctt ttaactggtc gaaaaaatgg ttttgaaaaa ggacattacc
     6061 gtgaagtgag cggatattcc aaccaacatg aaagtaaaca tgactatttt acagtggggc
     6121 acacatctac atctatcagc ttagcaacag gtttagctaa agcgagagat ctgaagaaag
     6181 aatcaggaaa tgtggtagca tttatcggtg acggctccct aagtggtggc ttagcttttg
     6241 aaggattgaa caatggtggt gttttacaat ccaatctaat cgtattagta aacgataatg
     6301 agatgtctat tgatgagaat catggcagtt tatataaaaa cttagctgag cttcgtcaaa
     6361 ccaacggtaa aagcagcaat aacctattta aagcaatggg atttgattat cgttacgtgg
     6421 ataatggaaa cgatctggaa acggtgatcc gtttatttga agaagtaaaa gatattgatc
     6481 atccgattgt acttcacgtc catacggaaa aaggtcgcgg ttatcagccg gcaatcgata
     6541 ataaaatgaa atatcattgg catgtaccat ttgatctgtc caccggggag gcaaagcaag
     6601 taacttctgg agaaacattt aatatgatca tcatggatta tttggataag aaaatgcaaa
     6661 caagtacagc tcctattgcc gcagtcaatg cagcgatacc aggcgccttt ggactgaaaa
     6721 cattccaaga aaaacatcca gatcattatt ttgacgtggg gatcgctgaa cagcactcta
     6781 tcactttcgc ttctgctttg gcttctcagg gagtacgtcc agtcgtcttc caatcaagta
     6841 ctttcttgca acgggcatat gatcaattat cacatgattt agcgatcaac gagaatccag
     6901 tgattatttt agtcggtggc ggaacgatct cagctagtga ccgaacacac caaggaacat
     6961 ttgacattcc ttacttatca agtatcccga acatcaaata tcttgctcca gcaacaaaag
     7021 aggatatgat ctctatgcta gattgggcgt tcgaacaaac agcgcagcct gtagcaatcc
     7081 gaattcctac acatggtgta gaacatggta cagctatcgc aaatgattat agtattccag
     7141 cctatcaaac agtaaataat ggaggaaaag tagcaatttt agctttaggc ggttttcttg
     7201 aattaggaaa agaaacagta aaagctttta gaaaaaaagg aatcgaagca acgttgatca
     7261 atccaggaac gatcacagaa aatgacgtag aaacattaga taaattaaaa gaaacacacg
     7321 aattagtcat cacattagaa gatggtagtt tgtcaggagg atttggcgaa aatatcagtc
     7381 gttattatgg tgattcttca atgaacgtat taaattttgg tgcagagaaa gaattcacgg
     7441 atagcgttcc tgtagggcag ctttatgaac gttatcattt aacaccaaaa caaatcgttg
     7501 aagatagtct gcgtgtcttg aatattcaat aattcattat gctcaccatc cagataattg
     7561 tttatactag tatctggatg gttttttcat tataaaaagc aaaggggtgg atgttatgta
     7621 tcagcaagta gaagaatatg tcaaaaagtt ccaagaaaaa tatcctagtt atcaatcaga
     7681 aaaattaggt ttcttttcat ttggggatac agaaaaaatg gcagacgagt tgagcgaact
     7741 agttgtaaaa aagataaaga ctggtacatc aagtggttac gatctgtata aacaagagaa
     7801 tgagccttta ccaaaagttg gtcaattaga cgtggtcctg aatggaaaaa atgaaccagt
     7861 ttgtatcatc aaaaatataa atgtgaccat cttgcctttt agtgaagtca cgaaagagca
     7921 tgcttggaaa gaaggagaag gggatcggac attagcttat tggcggaaag tccatgctga
     7981 gttttttaaa catgcttata aagaagcgtt gaacatagaa tttacagaag agaagctggt
     8041 cgtatacgaa gaatttgaag taattttctt ttagtaagaa aggtctgctg aaagaaatag
     8101 ctcattattg tctcctgaat agaaaagggt tacattttta tatgaagctg tatttttata
     8161 taacattact ggaggagata ttgtggatac actggaacaa atcaaaggcg gagtcgtcgt
     8221 ttcttgtcaa gctttggaaa acgagccgct acacagttct tttattatgg ggagaatggc
     8281 tttggctgca aaagaaggcg gagcagttgg tattcgagca aatacgacag aagatatcaa
     8341 tgaaatcaag cgaatcgttg atttaccggt aatagggatt atcaaaagag attacgatgg
     8401 gtcagaagtg tttattactg cgacagaaaa agaagtggaa gaacttttgg agacgcaagc
     8461 agaaatcatt gcactggatg caacttctcg taaacgtccg acagaaaaaa caactgctga
     8521 acttgtccaa atgattcacg aacacggtcg gttagctatg gcagatattt cgacttttga
     8581 ggaagcgctt caagcgcaag aagatggttt tgatcttttg tctacgactt tagcaggcta
     8641 tacagaatat tcacgaaaga cgcagacacc tgattttgat ttattgaatc aaatcataga
     8701 acaagtcgat atcccagtaa ttatggaagg acatactgac tctcctgaac aagtagagaa
     8761 agcatatgaa ttaggtgctt tttcagtcgt agttggatct attatcaccc gtccgcaatt
     8821 gatcactaaa agatatgtcg aagccgcaag taaagcaaat aactaaaaaa cacgcacggc
     8881 acagattctt gacaaaaaag aaaaattgat agatagttta aagcagattc taagaagatg
     8941 aaaaaagcat tacttttcat tttgtcttca agatctgctt tttaacgaat tttatagaaa
     9001 gaaggcgaaa ccatgtttga acggagtcct tcagaattga cagaacgtga aaattacaag
     9061 ttgctgattg gttcagtcat ccctagacca gtagcagtag taacgactaa atcagcaaaa
     9121 gatatagtga atatcgcacc cttcagttac ttcaatatcg tcagttcgaa tcgacccatc
     9181 ttatccttgg cgatccagag aaaacaagat gcagtaaaag acacagcaaa gaatattctt
     9241 gagacaagag aagctgttat ccatatcctt gatgaggaca acgtagaaga agtaaataaa
     9301 acagcagcca atctgcctaa tgaggaaagc gaactgtacc tgactgactt gactttaact
     9361 gattcagtaa tcatttcagt accagcattg acagaagcaa aagttcgttt tgaaacatcc
     9421 ttatatgaac atgtcgagat acggaataaa aataaagtaa cagctgattt atttttgcta
     9481 gaagtacaga aatatcattt aaatgaaaca gtctatgatg ataagacagg aaggatcgat
     9541 ccaagaaaat tgaatgctgt aagccgtttg gcaggaaatg attatgcagc aataggagaa
     9601 attttcacga ttgcacgtcc cgaataaaaa ggagcactag ttatgttaaa aataagctat
     9661 aaaccatcga cagattcaaa agaaatgaaa aaagaatatg aaacagtgaa tgattttctg
     9721 caagggcagt acttagaagt tccgccattg caagaccatt ttgtcgttac tactgttact
     9781 ttagatggta aggaaataga aatgccagat caaacgatta gcggattgtt taattacttt
     9841 aacaaataaa tatttattcc gaaaagtgaa aaaacatata aaaaaacaca taaaactaaa
     9901 aaattatcaa agaatcctgg tgcaactgaa agaatttgca acgggattct ttcaacttat
     9961 ttgttatttt tttctaaaaa atattaaaga ttgttaaatt tcactatttc atttcaaatt
    10021 ccattgccta atcattagga aaagtctatc atgaactcgt aaatagaata tagtaataac
    10081 cttgttaggt gaggctccta tacaaacata ggctgttgcc cagaaacgtc gaaagtcgcc
    10141 aatgggtaaa acagaaactg ttggattaag gctttttcca atagctaaga atgttttctt
    10201 tacgttgtat agtgctaaaa ctcggacgat gagatgatgc taggtcagaa ttcttgttcg
    10261 aaaaggtttc tgaccttttc tttatatttt tgtgactgac ttatttgatg agacaaactc
    10321 gctcctcacc tgacaagtgg attgctgtgt gaggaggaga tgcggtgaaa aaagatcgat
    10381 tggtggaggt cgctcggatt cacttctggt tgcacaatac aaccagaaaa cacaacaagc
    10441 aaaactgatc tctatcatga gagattcata tgtcgatatt ccaggttacg gaatgaataa
    10501 gataaatgca gcttactctt atgggggagt tgatttatta aatcaaacat taaaggaaaa
    10561 tttcaaattt gaagctccct attatgcaag tatcacattt caagatttta tcgattgcgt
    10621 taatgaactg tttcctggtg gagtcaagat cgatgcagaa aaatctctag atttagatgg
    10681 cgtatatata aacaaaggag agcaagtgat ggatggtaat actttactcc agtatgctcg
    10741 atttcgggaa gacaaagaag gagacttcgg gaggatcaga aggcagcagc aagtgatcaa
    10801 agctatctct cagcagctga aagacgtaac ttcaatattc aagctaccca aagcggttgg
    10861 gaaattactt ggtagtatcc aaacgaacct tccagaaagt gtgcttctgg attgtggtat
    10921 ggatttcctc aaagacatat gttagaataa acaggtataa atagtgaaat aaaggaatga
    10981 caagcaagag aaggaggaaa aaatgaaaag aagtgacaag cacggcaaaa atcgaacagg
    11041 cgcttatatt gccggcgcag tgatcttaat agcagctgcg ggtggcggtt atttttacta
    11101 ccagcactat caagaaaccc aagcagtaga agctggagaa aagacagttg agcaatttgt
    11161 ccaagctttg aacaagggag attataacaa agctgcagaa atgacatcaa aaaaggcggc
    11221 aaataaaagt gcattatctg aaaaagagat cttagataaa taccagaata tatacggtgc
    11281 tgctgatgtc aaaggacttc agatatcgaa tctaaaagta gataaaaaag acgattctac
    11341 ttacagtttt tcatataaag caaagatgaa tacctcatta ggtgaattga aagatctttc
    11401 ttataaagga acattagaca gaaatgatgg tcaaaccacg atcaactggc aacccaactt
    11461 ggtttttcca gaaatggaag gaaatgacaa agtaagcctg accacacaag aagcagcaag
    11521 agggaatatt atagatcgaa atggtgaacc attagcaaca acaggcaaac taaaacaatt
    11581 aggagtcgtt ccaagtaaac ttggagatgg aggcgaaaaa acagccaata tcaaagcgat
    11641 tgcttcctcc ttcgacttaa cagaagatgc tatcaatcag gcgatttcac aaagctgggt
    11701 acaacccgat tactttgtcc cattgaaaat cattgatgga gcaacgccag aacttccagc
    11761 tggagctacc attcaagaag tagacggcag atattatcct ttgggtgaag cagctgctca
    11821 gctgattggt tacgtgggag atatcacagc agaagatatt gataagaatc cagaattaag
    11881 cagtaatgga aaaatcggtc gctcaggttt ggagatggct tttgataagg atcttcgtgg
    11941 gacaacaggt gggaaattaa gcattacaga tgcagacggt gtagagaaaa aagttctgat
    12001 cgaacatgaa gttcaaaatg gcaaagatat caaattgaca atcgatgcga aggcacaaaa
    12061 aatagctttt gacagtctag gaggaaaagc tgcatcaact gttgcgacaa cgccaaaaac
    12121 cggtgatctt cttgcgcttg ctagctctcc aagctatgat ccaaacaaaa tgacaaacgg
    12181 gatctcacaa gaagattaca aagcttatga agaaaatcct gaacatccat tcatcagccg
    12241 atttgcgaca ggttatgctc ctggatctac gtttaaaatg attacagcag caatcggtct
    12301 cgacaacggc actatcgatc caaatgaagt gttgacgatc aacgggctta aatggcaaaa
    12361 agacagttct tggggatctt ttaaaacaac gcgtgtcagt agtgatgtat cacaagtaga
    12421 cttaaaaact gctttgatct attccgataa tatatatgcg gcacaagaaa cgttgaaaat
    12481 gggtgagaaa aaatttcgta caggcttaga taaattcatt tttggtgaag accttgattt
    12541 gccaattagt atgaatccag cacaaatttc taatgaagat agctttaact cagatatctt
    12601 gctagctgat actggatatg gacagggcga acttctaatt actcctatcc agcaagcagc
    12661 aatgtattct gtttttacca acaatggcac acttgtctat cctaaattga ttgcagataa
    12721 agagacaaaa gataagaaga atgtcatcag cgaaacagca gtacaaacga tcgtgccaga
    12781 tctgagagaa gttgtgcaag atgtaaatgg tacagcacat tctctttctg ctttagggat
    12841 tccgttggca gcgaaaactg gtacagcgga aatcaaagaa aaacaggatg taaaggggca
    12901 agagaacagt ttcttgtttg ctttcaatct tgataaccaa ggttatatga tggtcagcat
    12961 gttggaaaat aaagaagatg atgattcagc aaccaaacga gcatcggaac tattgcaata
    13021 cctcaaccaa aattatcaat aaaaaattgc tttttaagta cagtaaaagg actgtggcgt
    13081 tatcgtcaca gtcctttttt caaataaacg gttttcacga tgtctctttc acaacttctt
    13141 tttgatttac tcacacttca taaacttttt ttgtaaaata tttgagaaca agtggagaaa
    13201 taagtgtact taataaaatc acgataacta aaggtgaata gtactgtggt tcgatcaatt
    13261 gactttgctg tccaatttgt aaaatgatca aagccatttc tccacgcgaa atcataccag
    13321 caccgaccat caatgaacta tgttgagaaa aaccggcaat ctgagcacca aaataacctc
    13381 caagcaattt ggtcaaaatc gctacaagcg tcaatataga aataaagagt agttgttcac
    13441 taaagtcaga aaaatcaact tctaatccta cactgacaaa aaatactggt ataaatactg
    13501 catatcctaa agcctctaca ttgtggtata cttcttcttt aacctttgtc tgactgacag
    13561 ctatcccagc aaaaaaagca ccaatgacag agctaagccc aacaagatcc gctacgtaag
    13621 acattcctaa acaaataact agcgatacga tgataataga agaatttgcg tacacttttt
    13681 ctgcaaatga aagtaggaaa ggcgcaatcc atttgactaa taagaaaata aaaacaaaat
    13741 aaattagctg ttcaatcaaa acaagcggta aagaagcatt gctagaagct tcccccgtta
    13801 gaaaagatag gctgaaactt agaactaaaa cgactaaaat gtcatctacc acagaagcac
    13861 ccaaaattgt tgatccttct tttgtattca ctacgtttag ttcttttaat acttctactg
    13921 aaatactgac agaagttgcc gcaagaataa tcccaaagaa aatcgcttca tttcccgaaa
    13981 cttggaatgc tttgcctgtc aaccagccaa aaacaaccgg gaagatgatc ccaagcaaag
    14041 caacgaacat accaggtcgg aaatattttt tcaaaagaga taaatcactt tccagaccag
    14101 ctaaaaacat taataagatc acaccaatct ccgaaaagtc atggactaga atatcaggtt
    14161 tgacccaatt caatccagct tggcctagca aaacaccaac aagtaattgt ccaatcactg
    14221 ctgggatacc taatctccgc gagatatgtg agccaatcgt tgttgaaatc aatatcaggc
    14281 ataaaatacc aataaattcc attctcatca ttcctttgta taaaatatag cccgaactta
    14341 gcataacata cattattgaa aaaataggaa aatatactca caaaaaaacc aacaatccaa
    14401 aagatttttt tggattgttg gtttttatac ggtctatttt aataactaaa aatgattaac
    14461 gtatagtcat ttttcttatt ctgatgaaat tgataatctc ctggatgccc atgaaaatca
    14521 aaataaagcc gaatatttgg aatagaagca tcaaactttt gaatggattg aacaataaga
    14581 cgaatccgcc aatcaacaac agaatactac tataaacact ccaactttta gcttttgtat
    14641 tcatgctgaa gaacaactgg aacaagctgt tgatgataac agctaatcca agaagaatcg
    14701 gcaggataga aacgattgca ggtgcaaaag catagacgat cagagctaag atcaggaaaa
    14761 aaagaccact gaacagaccg atactccaag aacctgtttt ccttttaaaa cggtaagcct
    14821 caaaaagatt caacaaccca agcaaaacaa gataggcggt gatcagataa ccgataaaat
    14881 gaaaaacagc agaagggttt agcacaatcg caatcccaga aataatataa acagcagctc
    14941 ttaataaggc gtatttttga atattttgtt taatcgtctc aaacatataa gaaaacctcc
    15001 tttgacttat tttaacgtga actagtcatt ttaccaaatt aaatgttaca aaatgagcga
    15061 aggagaagaa tatctctgga aaaatcaact tctgaggatc ttttccattt ttttgccttt
    15121 tgctagctca tcgatcattt tatctaaata acgaatttct ttcatcaagt tatcctcgat
    15181 gtcttctact cgtacaccac aaacaacacc tgtaatcaag gaacgtgaag gattggggac
    15241 aggggcttcc gcaaaaaatt gttcgaaagt cacttgtttt tgtagttgat attctagttc
    15301 tgtttgggaa taacccgtca gccaacaaat gatttcatct acttcctctt ttatacgatc
    15361 ttttctctcc gcttttgcta catacatagg ataaacgctt gcaaaacttg tcgtaaaaat
    15421 acgattttgc gccataatca gtcacctttc tttttttcaa attatttact acttatagta
    15481 tataagaaaa agagaagaaa aagcgattat tcaaaaaaac aaaaaggatt gtgacaaaat
    15541 tcttgtcacc atcctttttt ccgctctctg actttttaca atcttcatag ctcaagtgcg
    15601 catcagataa tcgaatgctc ctaaagctgc agtagctcct gaacccattg aaacaatgat
    15661 ttgtttgtat ggactatctg tacaatcacc agctgcgaaa acgccgggga tattcgttgc
    15721 gccatttttc tcggtcacta tttcatttct tggattcatt tcgatcgttc catctagcca
    15781 atccgtatta gggagtaagc cgactagaat gaatactcct gaaacagcta gtgtatgcat
    15841 ctccatcgta cggcgatcga tataggagag agattctacc tgattcgtac cgctgatttc
    15901 tttcgtcgct gcatgtttga taacagtgac attcgcaaga gagactagtt tatcctgtaa
    15961 gatttgatct gcttttaatt ctggtaagaa ttctagaaca tatacatgtt ttgctaaccc
    16021 agccaaatcg attgctgctt caacaccaga attaccacca ccgataacag caatctcttt
    16081 tcctttaaat aaagggccgt cacagtgtgg gcaataagca attcctttat ttttaaactc
    16141 tttttcgcct ggtacattga tagaacgcca gtgcgcacct gtcgcgatga tggcggtttt
    16201 tgctttaagt gatataccgt tagctaagcc aatattaata aaatgttgct ctttatttaa
    16261 ggaaacggcc tgttgattca tcataatgtc gatagggtaa ctacgcacat gactttctac
    16321 ttgctgcatc aattttggac cttctgtgta agaggtacca atcatatttt caatccctag
    16381 tgtttcaacg acttgtccgc cgaaagaatc agcgacaagt cctgtacgga ttcctttacg
    16441 tgctgcatag atagctgcac tactagctgc tggtccaccg ccaattacta atacatcata
    16501 aggttctttt tcaaacaact cttcttcaat caaagggcca gtgatttttt caacaatttg
    16561 ttcgatcgtc atgcgtccgc tactaaattc ttctccattt aaaaacacag ttggcactgc
    16621 catgattttt ttatcatcga tttctttttg gaacatccca ccttcaatca tcgtatgagt
    16681 aatatttgga tttaatacag ctaatatatt caatgcctgt acaacgtcgg ggcaattatg
    16741 acaagtcaag ctaacataac tgtcaaaatg caatgtttgt gttatttttt tgattttaag
    16801 actcaaagat tcactgattt tcggtgcccg tccactaatt tgtaacatag ccagtaaaaa
    16861 agaggaaaat tcatgaccga gggggatacc agcaaaaacg attccacttt ctttgccaac
    16921 tggattgata gaaaaactag gtgtgcgcat cgaatctctt ttttcccaag agattttagg
    16981 agacatttct gctatttcct tcgtaaattc agctagtttt tgactatttt cactattatc
    17041 caaactaaca gaaaaaacaa taggagattc aatcagtgct aaatattgtt cgagattttg
    17101 tttagtttct ttgtctaaca tatccaccac ctaaatcttt ccaacaagat caaaacttgg
    17161 tttcaatgtt tcgccacttt ctttccattt tgccggacaa acttcacctg ggtgggtacg
    17221 tacatattga gcagcgcgaa tcttatcaat cagtgcacta gcgtcacgac cgattccatc
    17281 tgcattgatt tccatagctt gaacgattcc gtctggatca ataataaatg ttcctcgctg
    17341 agctaatcct tgctcttcat ccaaaacatc aaaaatacga gaaatctgat gagacggatc
    17401 accgatcatc acgtattcga ttttaccgat agcatctgat gtatcatgcc atgctttgtg
    17461 agtaaagtgg gtatcggtag agcaagaaaa gacttcaaca cctaaagatt tcaatgtact
    17521 gtattgttct tgtaagtctt ctaattcagt aggacaaaca aaagtaaaat cagctggata
    17581 gaagcaaaga atactccagt tccccataag atctttttca ctgacttcta aaaattctcc
    17641 ttgatgataa gcatgtgcat taaattcttc gatttttttc ccaatcaatg acatagtaaa
    17701 acctccaata ataattattt atttataatt attgtaattt agttggagtt gcaaagtcaa
    17761 tggatatttt gttatttaat aaagattact caaaaacgaa ggttaattat aaaaatagaa
    17821 gaggtcgcaa gaaaatgcta ctgctggaaa tactcgggat aacgttgagt aacagtttcc
    17881 tgttctttca gcatcatgtg taagtgcaat cccgtttgaa atcgagcttc ttctggtttt
    17941 ttatcaacta aagccttgag taaatcataa tgttgttcca tgatcgtttc ccatggaagc
    18001 ccctgaatgg tcactcgtaa ccagcggaaa cgttctaaat gggtattatg gtcatctaac
    18061 cagttccaaa cttcttttct tcctgcaatt tcgaaacaag cttcatgaaa taaattatct
    18121 gcacggaaaa aagcgcgttc gtcatttatt ttgactgctt tttcttgttc ttctaaaatc
    18181 gtttctagca ctattcgtgt ttgtgtgtcc aatttggaac aacattcaat catgatttgc
    18241 tcttccaact gttctcggac aaagcgagca ttttctgcag aaacaagatt aattttggaa
    18301 acatacgtac cactttgagg tatcgtatac acgagttctt gctgacgtag ttgaatcaat
    18361 gcttcgcgaa tgggagtccg gccgatagca agatgttcct ccagtgcctt ttcagatatt
    18421 ttccttccag gttctaagtc agcatagata atttgtttac gaatcgcttg ataagcttgt
    18481 gattgcaagc tgcttttcat ctttattcct ccaaaatcat ttctatgaac gtagtataac
    18541 agaagaggtc tgaaaaacaa tctggtatgt cacattaact agtaaatttg tataaatagt
    18601 aaaattttgg ttgacatagc gatttttatt gtataaaatt cacttgaata caaaaactaa
    18661 tatgttagtt taggagggga aaaatgattg atttaaacaa ctggaggaac tttatccctg
    18721 aattatctca aaaagaagta gaaatacctc attttgaccg tgcatcatta agagaaaatg
    18781 gacaaaaaaa tcctgtctgg atccatttcg gtggcggaaa tctttatcga ggatttcatg
    18841 cagaaatcgc tcaacgttta gcggatctag gcgaattgtc cactggtgtc attgtttgtg
    18901 aaacattcga tgaagaaata attgaaaggg cttaccaaga ttttgatgat ttgattcttg
    18961 aagtggtcat gccaagcagt ggagagttcg tcaaacgtat attagctgcg acagctgaca
    19021 gtctgtattg tcatccagat tgttctgaac actttgataa gatgattcga cactttgaaa
    19081 atcctagttt acaattagtt acttttgcta ttactgaaaa aggttatcga ttgaaagata
    19141 caaataataa atatatagga ccgattgcag tcgatataaa aaatggtcca aagaagccat
    19201 cacatacaat gagtattctt gctgcgctac tttataaacg ttttttatct ggagcttggc
    19261 cgattgcact tgtctctaca gataattttt cacaaaacgg tagtcaatta cgtacttctt
    19321 tgctaacgat cgcaaaagaa tggcaaaagg aaggttatgt acaaaataca tttatccaat
    19381 acttatcgaa tgaagaaatt gttgcgtttc catggacgat gattgatcgt atcaccccga
    19441 atccttcctt gtcagttagc aaaatgttgg caaaagaggg cttttcaaat atgtcgattt
    19501 tccaaaccgc aaaaggaaat aatattgctc catttgtcaa tacagaggac atccattatt
    19561 taatcatgga agatcatttt cccaatggac gtccgaaatt cgaaaaagct ggggtattct
    19621 tgactgatcg tgcaacggta gataaagcag atacgatgaa ggtgacgact tgccttaatc
    19681 ctttgcatac gtctttagct attatgggtt gtttactggg gtataggagc atagctgagg
    19741 agatgaaaga tccagattta tcgctgctag tttctgaaat cgggtacaat gaaggcctcc
    19801 cagttgtgga gtctccaggt atcattgatc caaagatctt tctggaagaa gtaattactg
    19861 tgcgcttttc taatccaaat attcctgata tgcctcagcg aatcgccacg gatacctctc
    19921 aaaaggtggc gattcgttat ggtgagacga ttaaaaaata tatggaaata gaagttaaag
    19981 acccgcagac acttgtattc ataccattga ctctcgctgc ttggcttcga taccttattg
    20041 gcattgatga tcaaggaaaa ccattcatcc cgagtccaga cccactattg acagactttc
    20101 agcataagct ttccgatatt caactgggta cgcaagatac atcacatatt catgagaaaa
    20161 tggctcctat tttgtcaaat aaagaaattt ttggtgtaga tctttaccaa gcagagcttg
    20221 gcagaaaaat agaagaaatg ttcatcaaga tggtagcagg accgaatgcc gtacgaaaaa
    20281 cattacagga ttacttacaa gaacatggag gaaatttatc atggaaatga cttttagatg
    20341 gtacggatca caggaagaaa agattacctt agatgaaatc agacagattc ctgcggtcaa
    20401 agggattgta ggcacattga tggatatacc agtaggagag gtatggccca gggagaggat
    20461 caaagaacta aaagaagaaa ttgagtctcg tgggttaaca ctaaaagtaa ttgaaagcgt
    20521 caatgtgcat gatgccatta aaattggatt accttcccgt gagcagtata tcgaaaacta
    20581 taagcagaca atccgaaact tggcagaata tggaatagaa gtcatctgct ataattttat
    20641 gcctgtattt gactgggtga aatctgacct tgactaccgc ttagaagacg gctcatccac
    20701 gttagctttt atatctgatg atattccaga tgatccaaga gaaatcgtcg cgcgcatcga
    20761 acattccagc aatgaatttg aattgccggg atgggaacct gagcgcttag ctcatatcaa
    20821 atccttgctt gaagcctatg catcagtaga cgaagaaaaa cttcgagaaa attttgccta
    20881 ttttctccaa tcaatcatcc caacatgtga agaggtaggg gtcaaaatgg ctgtacatcc
    20941 agatgatccg ccatactcga tttttggatt acctcgaatc gtaaagaatc gagaagattt
    21001 agattggttg tgccgcatag tagacagccc ttataacgga atcactcttt gtacagggag
    21061 tattgcagaa gatccagaaa atgatgtata tgggatttta gcagaatttt gtcaaagaga
    21121 tcgaatccca tttgcacatg ttcgaaatat taaattttta gctaatcgag atttctatga
    21181 ggcaccgcat aaatccgaat acggttcatt agacatgtac cgcatactaa aaacaatgta
    21241 tgacaacgga tttaacgaat acatccgtcc tgatcatgga agaatgatct ggaatgagac
    21301 aggaagacca ggatacggct tatatgatcg agcattaggt gctgtttatc taaatggatt
    21361 atgggaagca atcgaaaaag gaaacaaaag taaagataat tagtgaaaaa aactgtaatt
    21421 ttattatgta aataagaagg atgttcaaat tcttgataca taaatccgga ggttgttaat
    21481 aagcattcgg atttatgtat cttatttggt ctaggaagta acttgatttt cttttttcga
    21541 ttgatccatg agtgcttctt cttttaattc aaagatatat tctgagatcc tcataatcac
    21601 ttttttccag tcttctggtg tgatgattcc ttttaaaata tagatttttt tgatatgaga
    21661 aggcaattgt ttcaaagggc agtcgctgat aacgatgttg cagttctcca taaaatcatt
    21721 ttgtattttg atcgattcat ttgaaaaaat ttgttctatc ttaacgatca gatctttact
    21781 gatataaaaa tcacgcgtat agttcacacc aatcacaatt cgcggctgtt ttttgtagcg
    21841 atcatacaaa tgtactaggt cttcaaccat ccattgcaca ttttcctttt ctaaaataac
    21901 tggtaacaag tgttgatttt gttctctgaa atccatataa aattgttcaa tggcggtttg
    21961 gacttctttc aacacgctat gttcttgata aagcatgaaa gtaggaaggg gcgtatttgg
    22021 ttgattgaag ttaagaaatc cattataaag tttatttcgt gcgaatgcca atgagtaaag
    22081 aatcttttct ttttcaggta taaacaaatc aaatacagta caaaaggact ccaccatttc
    22141 tcttgaataa agaacatgag gaacgtttgc tttttttaaa agtttgtatt gctccaagct
    22201 tgtttcttcc gattcgattt tcgtgataga aagtcgagct aaaatattca ctaagatgcg
    22261 ttgttcgcga caaattggca gattaggtcg caaaatatct acagagggat caataaaaaa
    22321 gtcaatatat tcatactctg tgaattcttt ttgtacgtct ttcacagaag ttgcaggaaa
    22381 attctcttta catattttta atagaaaata taatttatct atcataccgc tatttagtcg
    22441 gtcaagtact tcttttttaa aaaaagtatt catcataaaa gccactactt gcggatcttc
    22501 atcataaaat tctgtagcag tacttgaaaa gatgttccaa taaatatcta atgctgcata
    22561 ttgaatttgt acctcttttc cagaaaaaga ctttctgcca ttattagaaa aggagataga
    22621 caaaccgtac aatgctaaaa atgcattaat ctttttcatt ttcgtataca aataagaggc
    22681 actatagttt gtttgctgac ttaaactgat aatcgaattt gtctgacagc tgaacaaaga
    22741 agtcaagatc tgataactga ctgattcgtt gcagtatctt ccaaatagac gataatagca
    22801 gtaagccgga tcaattcctt caaaattcaa ctttaaaaaa ggtttttgct tatcaatatg
    22861 cagttctgtt agattgagac gctcaaagtc ttgttctaat tctttgatgt atagtaaaaa
    22921 atttgattca gacatatgga aatgatctgc taaatattgt gtagtaataa agaaacgatg
    22981 ttcagatagg aaaagaaaaa tatctaattt tgtattgctt tttttcttca agagaaacgt
    23041 tttaatcgct tcttgagttt gcatgaaaga ggctcctttt tacttaaatt gttaaaactt
    23101 gaaaatatta ctgttttttt cataaattta gacaaaaaaa cagtaaacat ataggtagaa
    23161 tctctactat cttatttctt gcatacaaaa aaatcaagga gtgagagagt tatgagatat
    23221 tcaaccatct taatatcaac atttgcagcc ttaagcttat cgcttactat aaatcagaca
    23281 gtccacacag aggagataga aacagccaaa tggacagaaa ccaagtgggc caacgtcaat
    23341 cgaattacct ttcaggatga attttcatcc ttcaattcag gagtcgcaaa attaagaaaa
    23401 ggacaaacag cgaccatcaa agcaaaaatt gactattcag gagacttagc acctatacta
    23461 caatcagctg ttacatttga gaatgttgat cccgctttgt cgattggcta tgacgagaac
    23521 actttgacta tccaacacaa gcaagcgata tttaccttca ccgttacatt aaatcaggac
    23581 ttgttaaaac cagcgctttt tactgtcaag gtatcagatg gactaccgaa cgatcatcat
    23641 catttaacgc cgtatagtca gcggcagaca attgagcaag attcagctat cgactcagga
    23701 ggagatcttg ttgaagaacc aacagataaa ccagaaaatg aaaataagcc agaagtaccg
    23761 cctacagaaa atccagacgg agaacagaaa ccggaaatag aacctggaga agaacccgat
    23821 acagaaactc aaccagagcc agacaatgaa tcaaaacctg aaataacccc tggagaaaaa
    23881 ccagatgtag acccagaaga aaaaccagat gtgactccag aaccagatac ggattctgga
    23941 aaccaaacag taccggaaac aaatccagac acagataatg aaactgaaaa tccagaaaaa
    24001 ccagaggtag ccccagaaga aaaaccagat gtaactccag aaccagatac ggattctgga
    24061 aaccaaacag taccggaaac aaatccagac acagataatg aaactgaaaa tccagaaaaa
    24121 ccagaggtag atccagaaga aaaaccagat gtgactccag aaccagatac ggacgcaaga
    24181 gaccaaggaa taccagaaaa aataaacaaa aaaacaattc aagaggatgg aaaaaaagag
    24241 agtaaaaaat caaatctagc aattctaaaa ataaatgaag agcagctgaa taaaaaatca
    24301 cgaatatttg atagcgccca atcagctgaa accttaaaaa gtagcaagga tacaaccttt
    24361 gctgtcctga aacgaaaaat aaacagctac caaaatccgg agagtcacaa aacaaagtta
    24421 tactgtggag cggaatcatt ctattaagta tagcaacaat gctttctgca aaaagattta
    24481 aacaaaacag atctctctaa catttgaata atgtctgtga acgcattttt caaataaaaa
    24541 gaaatatcca gaaaatgacc ccaaaatacc agattgaaat ctgatatttg gggtcgttca
    24601 tactttatct ttcttcatat ttattttaag ggatatctgt ttcttttgga agatggttcg
    24661 ggatcttttt cactttcaat acatctaaaa agaaggtaaa gatcggaatg ccgacaatca
    24721 agccccaaac gccaaagaac cgttcgctaa caagtaagac cacaaatgta taaaaaatcg
    24781 gcagttctgt tttgctggac atcaacttcg gattcagcac ataagactca attagatgga
    24841 caatcaaaat cgtaatcagg atataaacaa catctcggat gcctccttgg gaataagcta
    24901 tgaaagatag aggaatacaa gaaatgataa cacctgctac tgggatcaga cttaaaatga
    24961 aaatcatgat cgctaaactc agcagctgat gaaagccaaa tacagccaag gcgattgtag
    25021 tgagcaacgt atttaaaaga gcgacaacaa attgagcttc taataccaaa ccaaatgtat
    25081 tgacaaactt atcggcaaaa tagtaaatat cttgaaagaa ccaagaaaat tcacttttta
    25141 aaaacaatct tgagaataca attgtttttt tcttttcaat cataaaaaag aaacttaaga
    25201 tgaatgacat agcaaacgcc actgccattt ttcctatatc ctgtaaatag ccaagcgcaa
    25261 tcgaagcgcc attttgaagc tgttcaaaaa aatcgtttcg ctcaatataa gtatggatat
    25321 attgtaaaac aggatctgca tcttttggct gatgctcgta aaaattaata acggactgga
    25381 tcatgtcaaa tgtttgatga ataagcatcg ggatatactt tgtgaatgcc agatagataa
    25441 ggtaaacgat cagtgtataa atcatgatag ctaaaacacc tgtagggatt cggacaaatc
    25501 gctgaatgat ttgaacaaga tgaatcatca aataagtaaa gataaatgtg agcaaaatgg
    25561 ttgtaatcat acttctaact aagaaaagaa caaaaacgac aaataataaa acagtgagac
    25621 ggcgtatttt ttcattcgcc aaaaaacgct gataaacggt caaatcgaca acctccaaat
    25681 aacaaaaaat aaacacgtta ttcattatat gatggaatat gaaaataaga aagagcaaaa
    25741 agaaaaaccg ctaaatgacg ttatcttatg agttggtttt cctcataaaa tcgttcatct
    25801 agcagtttca gccctttttc tggtcttgat gaaaattatc tagcattttt cgggtcagat
    25861 gttgcagtgt atccaattct tcctgttcaa gtggaagata agacttgatc ttttgtggaa
    25921 taccttctgc ttgtttttgc aacgcagcac cttgagcagt cagcgtaaca tttacgattc
    25981 tttcatcacc cgtttcacgc tgacgattaa tataattttt ttctgctaac ttttttagta
    26041 agggagtcag cgtaccagaa tccagacaca aatcatttcc tagctctttc actgaagtct
    26101 ttttcttttc ccataaaact aacatcacaa gatactgggt ataggtaaga ttcagcggct
    26161 tgaggagggg agtgtagtgt ctaatgattt ctttagaggc ggcatataaa ggaaaacata
    26221 cttgattaac taaatataga tcttccattt ttccacctcc gctgttttac tatagtgtat
    26281 catagcggat ttacacaaaa aagtctattc actaactgct ttcagagtaa cttctatatt
    26341 tccagctgta gcttttgaat acggacacac tttatgcgct gcctctaata attcttgcgt
    26401 ttcttccaga gaaagacctt cgatagatcc ttcaatctct acacctaaga caaagctcgt
    26461 ttcactttct gaataaaggg aaacttgtgc actgacagta gaagccccag agatattttt
    26521 ttgctgtttg atcaattcta atgcactgtt aaaacatgca ctgaaaccag ctgcaaacaa
    26581 ttgttcaggg ttggttgcat tttcgacgcg tttaccagga gctgcaatat tcaattcgaa
    26641 tgtacgatcg ggattatgca cttctccaga gcgtccgcct gtgttgatca ttttcgtaga
    26701 atacattttt ttcataaaat taccaccttt aattatattt tatacaattg aattttacac
    26761 aatataattg tggaaagcaa agaaatggat tggcataaga taaataagag aaagcacatg
    26821 aaacagacgc gctttctcga atagcaaaca tatacaaaaa atatcagaga caaaaaataa
    26881 tctcatcata aacattacat atatttctca aaaagttgtt ttctttcttc aaaaattact
    26941 tcacgatgga cctgatgaag catccataaa taaccaaaag gatctctgaa cattgagtta
    27001 gtcacaccaa agtccatcat ttctgtcatt tcttgaatct ctacacagcc atttcgtaat
    27061 gctttattat gtgtgtcctc gatatcagag acgatgatat tgaaccagat cgtatttgga
    27121 tgttcagcag taggagcagt caaaccaaga gacgtgtttt catccagcat atggaatctc
    27181 gtaccataca aggtaaaaat gacttcatta ttgcctctag ggtaatctgt tgcctcaatc
    27241 agttgtattt catcaaagat tgtttgatac agttctagtg ctttcaaact atcatttaat
    27301 acaaaatcga tttccgttcc tttatgcata aagatctcct ctccttttca gtcgaacagt
    27361 tactagattc ttttattata ccagctaaag aaaacgcatt caaaaaaata gcggatttac
    27421 ttaccaactc attcgattgg atgataagta aatccgcgtc ccattacttc tgctacgctg
    27481 ctgacaatga caaaggcact tggatcgatt tcttctatca atggtttcat tcgggaaaat
    27541 tcatgatcag tcacaacgat caataaaacc tcttttgact ttcgattata cccgcctttt
    27601 gcctctagca gggtaaggcc acgtccaatc tcagcactta agcgaaggcg gatgtcttcc
    27661 aaataatgtt cactcatgac cataacagat ttctttcgat tgatacctgt ttcgatataa
    27721 gtcatgacaa ttgaagtgat tgcaatagat aaaatagcat aaagaaactc ttctattcca
    27781 aaaataaaca gattaagaga aacaacgaat gcgtctgtaa aaaataagcc aatcgaagta
    27841 ttcaagtgga aatatttttt aaaaatgagg ggagggatcg tcgtaccgcc gctagaagag
    27901 ttgtttttat ataaaatcgc aactcctaaa gcaaaaatcg cacttccaaa aatgacagac
    27961 aacaaccgat ctgaagtaat cattgtttct ggaactattg caatgattaa aggaaaaacc
    28021 aagcttccga aaagtacttt aaaaaagggt tttttaccta aaaatagaag agctagtacc
    28081 aacataacga tattcaacac taaaataact atagctcggt caaagcctaa agcagcttcc
    28141 agtaatattc ctagaccgct gacacctcca gcagcaatat gatgaggccc taaaaacata
    28201 ttgatagcga ctcctaatat gaagagggca aaaataatct taatgtatgt ccatataaat
    28261 tgtctcgttt ctttcattta ttcacttcct taattcatta ataatactct tatcttatta
    28321 taacttactt ttcaccttaa gttaacttta attaataaaa aaattaggct agtctaaatt
    28381 attatgtttc attcttctag aatatacttc tacgccaaaa actgttaaaa aacttttact
    28441 ttagaaaatt ggagaaattg atcgcttaag ataaattcag gacactaaat agtacaggaa
    28501 gtagactaaa acttttaaaa gttttaagtc tatctatttg gcaagtttaa aaaataaaaa
    28561 ttcggtatca aaaaactgtt accgataaca tttttgaaag cgttgtcttt tgcttctcta
    28621 tcacttatag tgatgacgtc atattaaaac acaaggagga aatcaatgga tacagctgca
    28681 atttatcatc gaccggaaag tgaatatgca tttctatata cgaatacaag atttcgtatt
    28741 cggcttcgta ctaggaaaaa tgatatcaaa aaagtatatg tgctatgtgg agatccatat
    28801 accataacaa ctgaaaaatg gtatcaaaaa caacgaccaa tgaaaaaatg tctaagtacc
    28861 aatgttcatg attattggga aattgaagtg acgagcgaaa caagtcgctt acagtatgcg
    28921 ttccatgttg ttggggaaga taacacggac tgtttttacg gtgatcaagg aatttttcct
    28981 tatcgagaaa atgtgattac tgaaccaaat ttttattttc gaatacctta ttttcatcaa
    29041 atcgatcgat tcactattcc agaatgggta aaagaaacag tatggtatca aatttttccc
    29101 gaaagatttg caaacgggga caaagcaaat gaccccgaac acactttacc ttggggaagt
    29161 aaagatccag accgagaaga ctttttcggg ggagatttgc aaggtgtgat ggatcatttg
    29221 gattacttga cggaccttgg catcaatggc atctattttt gtcccatatt taaagccaca
    29281 tccaatcata aatacgatac gattgattat tatgaggtgg atcccgcttt tggcgataaa
    29341 aaacttttaa aaaacttgat tgatgaagca cataaaagag ggatacgtat catgttcgat
    29401 gctgtattca atcatatggg tgtccattca ccacagtggc aagacgttct caaaaacgga
    29461 gaaaaatcga tctataaaga ctggttccac atccgttttt tcccagtaga ttcttatcag
    29521 atgactgact taccagaaac tgctgaaaat atcccatatg atacttttgc ttttactcca
    29581 ttcatgccga aactaaatac agcaaatcca gaagtgcaaa aatatttgct ggatatcgca
    29641 acttattgga taaaagaatt cgatattgat ggatggcgtc ttgatgttgc taatgaagtc
    29701 gatcatcatt tttggaaaaa attcagagaa gcagttacag aaatcaaacc agacatctat
    29761 atccttggag agatttggca ttcctctcaa gcttggctgc aaggggatga attccatgca
    29821 gtgatgaatt atgcatttac agattcgatt aaagattatt ttgcaaaaaa gaaaatcaca
    29881 gcttcacaaa tggtcagtgg aatgaatcat cagcaaatgc tttacagaga tcaggtgaac
    29941 gaaggaacat tcaacttatt agattctcat gatactgcca ggatcttgac cctttgccaa
    30001 ggtaacaaag aattgatgaa gtctgtgatg gcctttatgt ttcttcaaaa agggtctcct
    30061 tgtatctatt acgggacaga aatagggatg actggtgaag atgacccgga ttgccgcaaa
    30121 tgtatgatat gggagaagga ggaacaagat ctagagctat tcggttttat aaaagaactt
    30181 gtttctctaa ggaaacagtt gtctaagatt atttctgaag gttctactca gtggctaata
    30241 gtaaatgatc gtgaagataa gctctatttc acacggaaac tagagggaca gatcatctat
    30301 gtttacttta atcagtcaaa agaaccttgg gtagtagaac aggaaaatga ggtgattctt
    30361 agtcaaaatt gtcagttgtt agaagacggg aaagcagaga tacgacaata cggatttttg
    30421 atcatgtgtt gaaaactgtt accggtaaca acaagaaagc gtttgcaaat gaagatttgt
    30481 gcccattata ataagggtgt aacagcacgt tgaatacaaa ggaggaaatg aagatgaaaa
    30541 aaagaagtgt gaaacagttg ggtttagggt taatctcttt aggaatctta ggcggattag
    30601 cggcttgtgg caatggtaac tcttcagcag aaggggaagc cgatgaagga aaaacgttaa
    30661 cagtttccgt tgattctgga tataaagatt atataaacga aataaaaaac actttcgaaa
    30721 aagaaaacga tgtgaaaatc aagctagtag aaaaggacat gttcgatcag ttggaatcat
    30781 tagcgttaga tgggcctgct ggaaagggac ctgacgttat gatggcagca tatgaccgga
    30841 tcggtgcgtt aggacagcaa ggacatctgg cggaagtaaa actgggaaat gaagcagctt
    30901 acgatgaaac agacaaagcc caagtgactt atgatggaaa aatctacgga gaacctgcag
    30961 taatcgagac ccttgttttg tactataaca aagatttagt cgatacagca ccatcaacgt
    31021 ttaaagattt ggagaatcta tccaaagaca gtcgttttgc ttttgagtca gaagcaggaa
    31081 aaaatacagg atttttagct aaatggactg acttttatta ttcctatggt ttaattgcag
    31141 gttacggtgg ctatgtattt ggtgatgatg gcacaaatcc ttcagatatc ggtttgaata
    31201 atgcaggtgc tgtagaagga atctcttatg caacagattg gttcaaaaat gtttggccaa
    31261 agggaatgca agacataaaa agtgcaggag acttcgccag ccagcaattc atgtccaata
    31321 aaactgcagc aatcattgac ggtccatggc aagcgcaaac atacaaagaa aacaatatca
    31381 attatggtgt agccaaaatt cctactctaa ataatggaca gccttatcaa ccgtttggcg
    31441 gaggaaaagg atgggtagtc agcaattatg ctaaaaacaa agacctctct caaaaatggc
    31501 ttgattatgt aacgaatcag gaaaatcaag aaaaattctt tgaaatggta aatgaaatcc
    31561 ctgcaaacca acaagctagg gaaacagcaa aggctaaaaa cgatgaatta acaacagctg
    31621 tgattgaaca atatgaaaca gctcaagcga tgccaaacat cccagaaatg ggcgaagttt
    31681 ggacaggtgc agaaaacttg atgttcgatg cagcatcagg ttcaaaaaca ccaaaagaat
    31741 ccgcagatga agcagtaaaa acaatcagtg aagccataga acaaaaatac tgattaaaat
    31801 gataaccgtc catttttata aaaaatggaa caggtgcttc agataaaagt ggcaagagcg
    31861 agatggaaaa ttatcttgct cttgttgcca ttatcttaaa agcagtttgc ggtttagcaa
    31921 gtttagaggg ggcattcaga tgcagcaaga taaaacaagc aatatcaacg aaaaaaaaat
    31981 cacgctttgt tcacttattc cagggatggg gcagtttgta aatggccaag cttttaaagg
    32041 tatcgttttt ttcgccatat tcgtcctatt cattggtcag atgcttctgg gcggatttca
    32101 tgcattggta ggattggtta ctttgggaag tataccaatg gaagatcatt cattatttat
    32161 tttgattgaa ggcactttgc aattcatcat tacaatcatt ttcttgattt tttacggttt
    32221 gaatctttta gacgcttatc gagtagcgaa gatgcgtcaa gagggcaaaa aaatcaatcg
    32281 gacgatgaag gaagtcatac ataatatagg tgatgaaggt tttccttatc tattgacact
    32341 tcccgcttat cttctcatga tttttacgat cattttccca gtcctagtta cattgttcac
    32401 tgcatttact aattatgact tcaatcatat tccaccagcc agtttaattg attgggtagg
    32461 ggctaaaaac ttttttagta tcttcttttt aagctcatat cgtaatactt tttttgcagt
    32521 cttttcgtgg accgtgattt ggactttatg tgcaacaact ttgcaaatca cccttggtat
    32581 tctcacagcg gttgttgctc accagaaatt tattaaattc aaacgtattt tcggtatcat
    32641 tttcttatta ccatgggcgg tcccagcttt tattactatc atgagttttt cgaatatatt
    32701 caacgatagc gtaggtgcca tcaatactca agtgattcct ttcataaacc agcttccttt
    32761 tgtagatatc agtgcaatct cttggaaaac ggacccgaac tggacgaaag tagcaattat
    32821 cttagtgcag ggctggttag gatttcccta tatctatgtg atggttacag gaatcttaca
    32881 atcgatttca gaagacttat atgaagcagc aaaaatcgac ggagcaaatg catggcagcg
    32941 cttttcaaac atcacgcttc ctgctgtctt cctagtggca gcgccaacat ttattacaca
    33001 gtatacgggg aatttcaata atttctccat gatctatctg tttaacaatg gcggtcccgg
    33061 aagcgtaggc ggaggagctg gttctactga tattcttatt tcctggatct ataaacttac
    33121 gactggaact tctccgcagt attctatggc ttcagcaatc acgttgatta tctccgtcat
    33181 cgttatctgt gtgtcattgc tggtatttaa aaagacaaat gcgttcaata tgggggatta
    33241 acaatgaaaa aatttcattc gagtgctcga ttccaaaaac gactttctca cttttttact
    33301 tacttttttc ttttaatact gtcagtcatt atcatctatc cgcttttgat cacagcaagt
    33361 actgccttca agtcaggaaa tattgcagct tttagtttag atctttcaag tgactggact
    33421 ttaggaaact ttactcggct attcagtgaa acactttacg ggacttggta taaaaataca
    33481 ttgatcattt ctgtcctaac aatgatcgta caagtgactg tagtaacttt ggcgggctat
    33541 acttatagtc gctatcgttt tatcggccgc aaatcaagtt tgatgttctt tttagtgatt
    33601 cagatggtac cgactatggc agcattgact gccttttatg tcatggcttt cttattagaa
    33661 gcgctcgata agtactggtt cttgacaatg atctatatag gcggtggaat tccaatgaat
    33721 acttggctga tgaaaggata ctttgacact gtaccaatag atttagatga atctgctaaa
    33781 cttgatgggg cagggcattt caggattttt ttccagattg tattaccgct tgtcaaaccg
    33841 atgctcgccg ttcaagcatt atgggctttt atgggacctt ttggggattt catgttagct
    33901 aagttcctgc ttcgaacacc tgaaaatcag actgttgctg tcggcttaca aacatttatt
    33961 tctgatgtga caaaccaaag agtctctctt tttgctgctg gggcaatttt gattgcacta
    34021 ccgatttgtc tattattctt ctttttacaa aagaactttg ttaccggcct gacatctggc
    34081 ggaacaaaag gataggagca gagtatcatg caaacatttc cgttaaacta tttttccgca
    34141 ttacgtacgc caactcaagt gtttgcggga cgcaaactat tatcatggcc taaatttttc
    34201 ttgatatttg tatttttagt ttccttgatg gtcatgcctg tgactctttt ttatgccaat
    34261 cagatccaag cgattccatt agaacaattt ctatccgttc attcgctgat cgatgaacaa
    34321 ggaacccaaa aattttctga acttgaatta tctgaaactg ggttacaagc atcgcaacaa
    34381 acgatagctg tgacccctga aattttggta ggtgtgtctt tatctgagaa acaacaatcc
    34441 gatcatggaa cttttattga ttttgagaag gaacaatggg tgatccaaca aaaggataaa
    34501 tctggtatac gccgctatac gatgaattat agcccatctt tccaaccaga ttctgtacgt
    34561 acgcccgaag atttccaacg atttttagaa agagaatttt atgccagtaa tcgtccaaca
    34621 atcattttat cttatagttt aagtcttggt cttgtcctat ttgtcatgac gagtctcatt
    34681 ttattcgggg cttccttttt cttgtggatg acaagaaaaa gccaactttc atccattcat
    34741 acattcaaag agagtgcaaa tttgatgctg aatgttatgg gaataggttc catggcagca
    34801 gcagttgtag ggtttatcca ctttgacttt atcttgatgc taagtgtcca aacaacgata
    34861 actgtcttgc tgcttttatg ggtttttgtc aaaacaagat tcaaagataa gcgtgtcgaa
    34921 tgacaagttt aagcgattta tgcgacaatg aatgtgaaaa aaatgaaaaa taaagtagtt
    34981 tttgaaaaat ttctgaaaaa attaaacttc ttagttgatt cttttctttt ttagtattaa
    35041 cgtaataggg tagttttttt aaggaggaaa atcatgttag agaaaacttt atacaatcaa
    35101 ttattttcac gttctttctc gctccctgtc gaagtaaatt attgggacgg tacaacgaaa
    35161 caatacggag atacggacac tcctccccaa atcaaaatca atatccatga agaaatccca
    35221 atgaaagaga ttacaagtaa cgcttctttg gcactaggag aagcctatat ggatcatcga
    35281 atcgagatcg agggaagtat ccaagcattg atcaacgatg cttatcagca agcaaacagc
    35341 tttttacgag gaaaagatta tctaaaatgg ctgccaaaga aagaaaaaca tacgaaacaa
    35401 aaaaacaaag aagatatcca tgcgcattat gacttaggta acgactttta taaactttgg
    35461 ctagatccaa ctttgactta ttcttgtgct tatttcaata cacctgaaga tacgttggaa
    35521 caagcacaaa tcaataaagt ccatcatatc ttagacaaac tctttatcaa agaaggcgaa
    35581 acgttgcttg atatcggttg tggctgggga acattgatgt tcactgctac caaagagtat
    35641 aatgtcaagg caactgggat cacactaagt gaagaacaat acgatttgat taccaaaaga
    35701 ataaaagaag aacatttaga agataaatgc cgtgtattat taatggatta ccgcgaacta
    35761 aaaggcgaaa cgtttgatca tatcacaagt gtaggtatgt tcgaacatgt aggttctgaa
    35821 aatcttgaag gttatttcaa agtggtaaaa gatttattga aaccaaaagg aacagctttg
    35881 atccatggaa tcagccgaca acaaggcggt gcgacaaatg cttggatcaa taaatatatt
    35941 ttccctggcg gttatgtccc tggtgttact gaattagttg ataatattac aaaaaacgat
    36001 ttgcaactga ttgatttgga aagcttacgt cgtgactacc aattgacatt agaacattgg
    36061 acaaagaatt ttcatcaagt ccaagatcaa gtcacgaaag aaatgggtga ttccttctat
    36121 cgaatgtggg atctatattt acaagcttgt gcagcttcat ttgaatcaag taatatcgat
    36181 gtgattcaat atttgcttgt tcaacctgga aacaatgaca tcccaatgca tcgtgcataa
    36241 ttgaggcaaa agtactgttt aaagactatt taaaaagaag ctaagtttta tgatgctcca
    36301 gaagtgaact tttttgtcta acttctagga ttgtctctaa agcttagttt ctttttcttt
    36361 atattttcat aataaaagtt tggttcttta atttttaaac atgacagaaa attttttctt
    36421 cgttatactt gtaatagaat actattttat aacaaagggg atcgaatcaa tgaaaaaaac
    36481 tgttatttat actagtttat ttgcagcttt gtttttagct gcttgtcaat caaataccaa
    36541 tcaaggcaca tctgggaata cgtcttccag tagcgaacag cgctcttcac aggtatcgga
    36601 ctcctcaaca aaagcaagca catcttcgtc tagccagaca aaaagttcta gtgaagcaag
    36661 tactcagtca gatatcaaag tgtctgcagc tcgtgcgatc gaattgttcc aagataaata
    36721 cccagatact gcaattacta gtttggaatt agatagtgat tggggatctt acttctacaa
    36781 gatagaaggt gtcgatgatc aaaaagaata cgaagcaaga attgatgctc aaaatgaaaa
    36841 aatggagaca gagaatccag aaactctaga tcgagatgaa caaaatggtc aaaagaaaaa
    36901 agaagatggt ctggatgttg ataaattgat cacgattgag gaagcagcaa aaatcgccgt
    36961 cgacaaagta ggaagcggta cggcaacaga ttgggatttg gataaagatt taggtactac
    37021 ttattgggaa gtcaaagtaa aagacggcaa tcaaagtaca tcagtcaaga tcaatagcca
    37081 aacaggcgaa gtactgtcaa ctgaacaaga tgattaagaa tttcttcgga aaacaagagt
    37141 tgatttttct tttagtcatg atacactaga caaaataact tgtttgaagg agcgatttac
    37201 ttgagtttag aaacgacctt tgccaatcat atctttgcca atcctttgat gaatgcatct
    37261 ggtgtccact gcatgactac ccaggaatta gatgaactgg ctcattcaga agcaggagca
    37321 tttatcacta agagctgtac gatcaatgaa cgaaaaggaa atcccgaacc acgctatttt
    37381 gatgttcctt tagggagtat caattctatg ggacttccaa acttaggttt ttcttattat
    37441 ctagagtatg ctcttgcgta tgaaaaagtg caggaaaacc aaaatcaacc gttatttttt
    37501 tccattgccg ggatgagtgt ccaggaaaac ttggaaatgc ttgagaaaat agaaaaaagt
    37561 gggtttaatg ggatcactga attaaattta tcttgtccca atgtgcctgg aaaaccacaa
    37621 ctagcttacg attttgaggc cacttatgaa acactgaaag aagtattcag catcttttct
    37681 aagccgctag gaatcaaatt gcctccttat tttgattttg ctcattttga tcagatggct
    37741 gatatcttga atcagtttcc attgacctat gtcaatgcta tcaacagtgt gggcaatggt
    37801 ttgtatatcg atacagaaca agaagcagta gtcatcaaac caaaagaagg gttcggcggc
    37861 attggcggag agtatatcaa gccgactgct ttggcgaatg ttcgcgcttt ttatacacgt
    37921 ttgaaaccag aaatccaaat cattggtaca ggtgggattc ggacaggaca agatgcattt
    37981 gaacatctgc tatgtggcgc aagcatgtta cagattggta ccgagcttca taaagaaggg
    38041 ccggaaattt tttctagaat cataaaagaa ttaacgcaga ttatgtcaga aaaaggatat
    38101 acgtcaattg acgaatttaa aggcaaatta cgcaccattt catagcaaag agacgaaggt
    38161 catgattgat cttcgtcttt ttttataaaa aacactcgtc tgttcattcc tgtgcaagcg
    38221 tactcattgt atgttagacg aacttgtggg aaaataacag aggcaaaaag gaggataata
    38281 tgaatgatgc aacagaatta gcaaaagagc ttaaagaaaa agaatttagt tttcaagaac
    38341 tagttacgga tatacagaaa aaaataaaga agcaaaatca tgaattgaat gcgtttgtcg
    38401 cgcttgaacc attcgagagt aattcccacg agctattgat tccccagtca gaaaaagggc
    38461 cattggctgg tatcccattt cctttaaaaa tgctcggtca agaaaaaaag ggatggctag
    38521 ctacttcagg atctcgttta tttgaaacac accgagcttc tcatacatct aattatgtgc
    38581 ggcaagcaga agcgataggt ctagttcctt ttggacaaac caatgcgcca gagtttggtt
    38641 tcaaaaatat tacagaccca gtcatctatg gcccagcaag aaacccttgg aaccttgaat
    38701 gtacaccggg cggatcaagt ggaggagctg ctgctgcagt ttcatcagga atcgttcctt
    38761 tagctggtgc tagtgatggc ggtggttcta ttagaatacc cgcttcgttt tgcggattga
    38821 ttgggctgaa accttcgcga gggacgatgc cagttggtcc atatgcttgg agaggatggc
    38881 aaggagctgc tattgatttc ggcttgacag tttctatgag agacacggag gctttatttt
    38941 atgggatgag aagtatccat tccggtgcgc catatcaagt atcgccagtt gagtggcaaa
    39001 cacatccaag aaaaaaacgg ttgaagatag ctttttgtgt tgattcaccg atccactcac
    39061 agattagtga agaggcagta cttgctgtaa aaaaagctgt agatttcctt ggaaaagaag
    39121 ggcatgattt gacagagatt ccttacccac tagatggtcg taaactgatc acgtcttatt
    39181 atcagatgaa tggcgcagaa acagcagcaa tgatccgctc gattgaaaca ggcatccagc
    39241 gagctgtcag aaaagaagaa cttgaaccca tttcttggac tttgttccaa tatggtcaga
    39301 agctctctgc cgctacttac atcgattctc tgcatgtatg ggatgaagca gcaattgtca
    39361 tggaaaacct acatcaagaa tacgatctat tcctttcacc aacgactgca tttaccgccc
    39421 ctaaaatcag cgaagatttg caaagtgatg cgataagagc acagatggaa cacatcagtg
    39481 attgttctga agtagaaggt ttagacgttg tttcttccat gtttgaggag agcttgaaga
    39541 tcacacctta tacacagttg gctaatctga ctggacaacc agcaatcagc ttgcctactc
    39601 atttgacaaa agaaaacatg cctctaggaa tccaatttat ggctgccaga ggaagagaag
    39661 atttgctatt tcaaatcggc tatctatttg aagcaaatca tcagttccat ttaccaaatc
    39721 catggaaata gcagaaacaa ggagaagaag aatgaagaaa aaaagattgt ttgctctaat
    39781 aactagtgcc ttttttattt taagcgcttg cggtacagct gccgctaatc aggaagataa
    39841 cagctggagt aatgtagaaa aaaagaaaga attagtagta gcgacttctg gcacactgtt
    39901 tcccgcatct tattataatg atcaaaatga attagttggt tatgatgtag atttggcaaa
    39961 agaggtggct aaacggttaa atgtcaaaat ctcctttaaa gaatacaacg tggatggaca
    40021 aatcacttct gtttcaaaaa gagaatcaga ttttgctgcg aacgattttg gtatcacaaa
    40081 agaaagagaa aaaaaattct ccctttcaga gactttcaaa tattcatttg acagtatgat
    40141 cgtacgaaaa aaagatgatt caggaatcca ctcacttgaa gatcttaaag ggaaaaaagc
    40201 agctggcgaa cccaatacta gctatatgcg tttagcggaa aaacacggag ctaaattagt
    40261 cacatatgac aatgccacga atgatcagta tttaagcgat gtagcaaatg gtcgaacaga
    40321 tgttattcta aatgattatt atctgcagaa aatggccgta tctgctttac cagatatccc
    40381 tgtaaaaata ctggagaacg tttatttcaa tgaaaacgaa agtggttttt tattgaaaga
    40441 aggaaatgat gctctgaaaa agaaaatcga tggcgtatta aaagagatga aagaagatgg
    40501 gacgacaaag aaaatatctg aaaaatattt tcaaactgat gtttcagtca aaccgaaaga
    40561 aacgatggct gagtcggtga gtgagtgatg tactttcctc taattgattt ttccctcatg
    40621 tggacttcac ttcctttcgt actgcaaggc ttggtataca cattagggat tggcttcgtg
    40681 tcgtttcttt taggaaatct ggtagggttg cttttgacag ttttaggtct tttggattgg
    40741 ctgcctctga atgtatttat tcgtttttat ttatcgttct ttagaggcat tcccgcacta
    40801 gtcctgctgt ttctgttata ttttgggtta ccttatcaat taagtgcctt aacggcttca
    40861 gtcatctgct ttacgattac cagcagtgca tttattggtg aaatctatcg aggatcacta
    40921 gcaggcgttt cttcaggtca gtgggacgct ggtttagctt ctggtttttc tttctttggg
    40981 gtattgaaat atatcgtttt gccgcaagct tttcgaatct cagtaccggc actcagtaac
    41041 gtagctatgg atctagtgaa aggtacttcg ttagcagcaa caatcacagt gccagaaata
    41101 tttcaaaaag caaagatcat aggcggtcgg acattcgatt atttttctct ctatatttta
    41161 gttgcactga tttattgggt catttgtatc gggatcgaaa aagtgcaaca gtatttagaa
    41221 aaacgttcta tgcatcagtc aatctgaaaa atagaaatgg tgctagcgtg gctggcacca
    41281 tttctatttt ttgtttcttg tatattctgc ctagtatttt aaaaccattt catgtaaaat
    41341 gtaaatcgaa aatatgttcg gaggtagaaa acatgaagac cccgctaacc atcgaaatag
    41401 aatcctcgtt ataccaatat tgcatcgagc aaggcggctt ggttgtagaa gaagtcacga
    41461 tgcctgatga ccaaggaatt gtagatacgc ttagctgctt gacaaaattt gatggaagcc
    41521 gagaatggcg atgctatgag ctgaaagtga caaaagcaga ttttcgctct acagccaaac
    41581 tgtcatttgt tggacattat aattattttg ttttaccaag taaactatat gaagaagtaa
    41641 aaactgaaat ccctacagga ataggtgttt tagtgtatcg tccgtacacg gttgaagagg
    41701 agatgcctgc ctctggtaca tttctgattg cgaaaaaagc agcaaagaaa gagcttgctg
    41761 taccggaaga agctttgaca aaccgcttca tggcttcttt attcagggaa gtaagaaaag
    41821 caaagcaaat ggagcgaggc gtaaaatatt ttccaacaga tcaattgtac aaagaattga
    41881 aaagacgttc agaaaatcaa gatccatttt ctaacgaacg atattatgaa cggtttttag
    41941 aggaaatagc tagtcaggca atcaatgagt tgcaagaaga agttatcgcg cttcagcatg
    42001 attatgaata tttgaggcaa caacagcaga tccgtcggtt gcctacagag ccattggagt
    42061 gaaaaatatg tactatcctt atttaagagg aaaacaattt gacctattag cattaaaaga
    42121 agcactgtcg cgaggattgc tctccaataa aatccaacca gtgatcgaac cagtacgtga
    42181 ttccgctacg cttaaaaatg tgatcgaatt atttcaaaaa aagcaccatc caatcgctgt
    42241 gatccaaaat ccccaagtag gacaattcaa attattcgat cagcatgtgc acagttggac
    42301 agtcaaagaa aatagctctg tcgtccctgc acagatctta acgccagaaa atctcagtga
    42361 agtactggat tcacctccag cgtttcttgt tttcgatgga cagcactacc caaaagatac
    42421 agaggtgtgg aaacagttgg caggagttga ttcgaaattt ttgataccag atactagtcg
    42481 ctttcgcatc tggctgcccg aaaacaaaat tgtgatccgt gactcttttc aaacgagaaa
    42541 gcatgttgaa agttatgcag ataaaacaga tgactttttt agtgatgact atcttttttt
    42601 ccacgcagac ggatatattg gattttctga tttcacgatc gaaggtagcc gttatttcga
    42661 taaagggttc cctagccgag cgcttgctat ccatctaacg tatattgatg cttacggcaa
    42721 tatacgcgtg aaacattttg tctctgacag taacgactct gctaaagacc aagcattgaa
    42781 gtttcttgaa gcaggagata aaatgaaaaa atggatcatg cgtcaccatc atcaactctt
    42841 gattacttca ggaatgattg aattattggc tctttaccag caacaaaaat tccctggact
    42901 gggagtgttg aaaaagtggt cacttatgca tcatttggaa cttattagtc acctgctaga
    42961 tcatccaaaa gattggctta aatattattc aaaagttcag gaactatatg aagtgatcca
    43021 atgattagat aatgtaaatg aaaaaggaat agaaaagagg aaactggatg tatattcggc
    43081 aaacaaggaa agaagaagta gaagaagtgg tagaaatcat taatgccgca gcggatttca
    43141 ttgcttcgca aggctctcct caatggcaaa acgggcagaa accaacaaaa gaaacgattt
    43201 tgaacgatat tgaaagaaaa gaaagctatg tattaatagt ggaagatcaa attgctggaa
    43261 cagctgcatt agtctcaagc gtggatcccg tttacacaaa aatagatggt agttggaaag
    43321 aatcaactgg tccttattta tcgattcatc gtgtcgcttt agcagaaagt actcgaggaa
    43381 aaaaactagc aaaaccgttc ttagaacatt tgttgacgat tgcagccagc aaaaatatcc
    43441 aagatatccg tatcgatact tatccagcta atgaaccgat ggaaaagacc atctattctg
    43501 ctggattcac ttatcaaggg atgattgaat ttccttttga acacggcgaa agaaaagcat
    43561 atcaaataat catcaattga ctataaaatc atctgagcaa agataaagac attaacacta
    43621 ctgaaaaaaa caatcatatg atagccaaga ggttgtaaca gaagtggcca gcttcaaaaa
    43681 acaagaaaga atttccgaaa atgcttctca aatttttgtg gaattttagc gtattttacg
    43741 aaatagctgc tttctgaaac tcccttcatc gagaggtcgt gacatagctt ttgtcacgac
    43801 ctctcggctt atcctacgag tattattcga tacatttata tcaataatcc tttttttatt
    43861 ttatctgcag cttcttggaa cgctccatcg tttgacacga ctaaaagtga ggggatagct
    43921 ttcaaacgtt tcaactgtgc taaatcttct acataaaccg ccagtctggc tgaaatctgt
    43981 tcagatgaat ctccacgttt tttcaggcgc gattgcaatg tttctttaga gatcgtaata
    44041 aagataggac ggactaccgt cccgaaatac tcatataaat gccaaaaacc atttgctgtc
    44101 aaaacggcgt aacaatttcc tactgtcagt ttctttttaa tttctgcttt actggaacca
    44161 tatttatgtt gagcatattg gtcccactct gcaaactcat ttcccttgat catctgattg
    44221 aatgtattgt cagaaacaaa ataataatcc tcttgatctt tttccccagg tcttggtgat
    44281 cgattcgtgt aagtaatgat cttttgttcc ggctgaaaaa tagcttctgc gagtgaagtt
    44341 tttccagaac cagaaggacc gataaataca tagcaataat tcattgtcat ttctcctttg
    44401 atgattgaac aagtgaaaaa gctttggaaa atatttccaa agcttttaaa agtaactttg
    44461 cttttttgta tattatacca gcaagccagt cacaatagca cttaaaaagc tgactaaagt
    44521 cgctgttagc aaaattttca atccgtgttt tgcgacaaga tttccttttt cttcatttaa
    44581 tcccttcatc gcaccagaaa tgatcccgat agaagagaag ttggcaaatg aaacgaggaa
    44641 gacagatata attgctgttg tacgctcagt aaaatggaaa ttaccatttg ctaattctgt
    44701 catagcaaca aattcatttg taaccagttt agtcgccatg atactaccgg catccactgc
    44761 ttctttccat gggattccgc tgatgaaggc aagaggggca aagatgtaac ctaggatctc
    44821 ttggaaagtg atgccgaata tcccgtggaa gatagcattg atcatggcaa tcaaagcaac
    44881 aaaaccgata agcatagcag caaccgtgat cgccacatgg aaaccatcaa gaatgtattc
    44941 tcccaacatt tggaaaaatg tctgttcttt gttttcttca atgatcagct catcttcttt
    45001 ttcttctaat acatagggat ttacaattga agccagaata taaccgccaa ataagttcaa
    45061 aacaagggca gtgatcacat atttagaatc gatcagtgcc atataagatc cgacgatcga
    45121 catagaaact gtagacatag ccgatacact catggtgaac aaacgtttct cagataggaa
    45181 gggtaattcc ttttttatgg aaataaaaac ttccgattgt cctaaaatag cagaagctac
    45241 tccattataa gattccaatt tgcccaaccc gttgatttta cttaatccta gaccaacagc
    45301 tttcataaat aatggaagaa tcttgatata gcgtagaata ccgataatag cagaaataaa
    45361 tacaattggc atcaatacgg aaagaaagaa aggtgcactt cctttatttg ctacaccggc
    45421 aaaaacaaag tcaacacctt gcccagcaaa agcaagaaga tgatcaaaca tttttgccaa
    45481 tacagaaaca accgctgtac caaaagttgt acgtaataat acgaaaccaa gaacaagctg
    45541 taaaacgaac atcacaatta gtggtttcaa tttgattgct tttttgttac tgctgatcaa
    45601 aaaagcaagc cctaatgtga caaataaacc aataatacct aataaataac tcaaataatc
    45661 actcctattc caaattccgt tttattttac ctgttttgca aataaaatac taatctttag
    45721 tgaaattttc attacttttt tagagtgaaa cgcattcatt ttccattaga aaataaagcg
    45781 aacaaaataa
//
LOCUS       DAZUJR010000011        45147 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.011, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000011 DAZUJR010000000
VERSION     DAZUJR010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 45147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45147
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.011"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..1008)
                     /locus_tag="ACG804_000588"
     CDS             complement(<1..1008)
                     /locus_tag="ACG804_000588"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFS4831541.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(1188..1532)
                     /locus_tag="ACG804_000589"
     CDS             complement(1188..1532)
                     /locus_tag="ACG804_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HFS4831542.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(1525..1959)
                     /locus_tag="ACG804_000590"
     CDS             complement(1525..1959)
                     /locus_tag="ACG804_000590"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HFS4831543.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            2097..2834
                     /locus_tag="ACG804_000591"
     CDS             2097..2834
                     /locus_tag="ACG804_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4831544.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            2827..4038
                     /locus_tag="ACG804_000592"
     CDS             2827..4038
                     /locus_tag="ACG804_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4831545.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            4242..5024
                     /locus_tag="ACG804_000593"
     CDS             4242..5024
                     /locus_tag="ACG804_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HFS4831546.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            5094..5756
                     /gene="trmB"
                     /locus_tag="ACG804_000594"
     CDS             5094..5756
                     /gene="trmB"
                     /locus_tag="ACG804_000594"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HFS4831547.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(5854..7608)
                     /gene="ade"
                     /locus_tag="ACG804_000595"
     CDS             complement(5854..7608)
                     /gene="ade"
                     /locus_tag="ACG804_000595"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000034 - adenine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006146 - adenine catabolic process
                     [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HFS4831548.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNNQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            7740..8669
                     /gene="comGA"
                     /locus_tag="ACG804_000596"
     CDS             7740..8669
                     /gene="comGA"
                     /locus_tag="ACG804_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HFS4831549.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            8626..9675
                     /gene="comGB"
                     /locus_tag="ACG804_000597"
     CDS             8626..9675
                     /gene="comGB"
                     /locus_tag="ACG804_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HFS4831550.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            9672..9950
                     /gene="comGC"
                     /locus_tag="ACG804_000598"
     CDS             9672..9950
                     /gene="comGC"
                     /locus_tag="ACG804_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus major pilin ComGC"
                     /protein_id="HFS4831551.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            9925..10395
                     /gene="comGD"
                     /locus_tag="ACG804_000599"
     CDS             9925..10395
                     /gene="comGD"
                     /locus_tag="ACG804_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HFS4831552.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            10367..10714
                     /locus_tag="ACG804_000600"
     CDS             10367..10714
                     /locus_tag="ACG804_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831553.1"
                     /translation="MVAIQKELNKTGFVLLESLTALMIASVCVYLVSFGQLFLLQAEK
                     KSGEELLFIRMIYEDIKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAI
                     SIEKTSNSSIYAD"
     gene            10677..11102
                     /gene="comGF"
                     /locus_tag="ACG804_000601"
     CDS             10677..11102
                     /gene="comGF"
                     /locus_tag="ACG804_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HFS4831554.1"
                     /translation="MKKQVIPAFTLIECLIGLMILSSLLLTFNLLIQQTIQVSEFLQR
                     KDQKEWLIFLAQLEEELKSSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQ
                     PMLTSITELQLLEKEHTISFYVHFENGEDGYAIWTKNDQ"
     gene            11074..11433
                     /gene="comGG"
                     /locus_tag="ACG804_000602"
     CDS             11074..11433
                     /gene="comGG"
                     /locus_tag="ACG804_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HFS4831555.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            11605..12612
                     /locus_tag="ACG804_000603"
     CDS             11605..12612
                     /locus_tag="ACG804_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFS4831556.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            12637..13821
                     /locus_tag="ACG804_000604"
     CDS             12637..13821
                     /locus_tag="ACG804_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate/propionate family kinase"
                     /protein_id="HFS4831557.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(14258..15841)
                     /gene="abc-f"
                     /locus_tag="ACG804_000605"
     CDS             complement(14258..15841)
                     /gene="abc-f"
                     /locus_tag="ACG804_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protection-like ABC-F family protein"
                     /protein_id="HFS4831558.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(15946..16074)
                     /locus_tag="ACG804_000606"
     CDS             complement(15946..16074)
                     /locus_tag="ACG804_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831559.1"
                     /translation="MMRMTKITSNENYQRYHIAFSHAIGFTVAVDGTSLSKTVEFT"
     gene            complement(16419..16562)
                     /locus_tag="ACG804_000607"
     CDS             complement(16419..16562)
                     /locus_tag="ACG804_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HFS4831560.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(16785..17264)
                     /locus_tag="ACG804_000608"
     CDS             complement(16785..17264)
                     /locus_tag="ACG804_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFS4831561.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(17337..17621)
                     /locus_tag="ACG804_000609"
     CDS             complement(17337..17621)
                     /locus_tag="ACG804_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831562.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(17699..17893)
                     /gene="ssrS"
                     /locus_tag="ACG804_000610"
     ncRNA           complement(17699..17893)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="ACG804_000610"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(17965..19251)
                     /locus_tag="ACG804_000611"
     CDS             complement(17965..19251)
                     /locus_tag="ACG804_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HFS4831563.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            19389..20060
                     /locus_tag="ACG804_000612"
     CDS             19389..20060
                     /locus_tag="ACG804_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HFS4831564.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            20026..20514
                     /locus_tag="ACG804_000613"
     CDS             20026..20514
                     /locus_tag="ACG804_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HFS4831565.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            20527..21474
                     /gene="prmA"
                     /locus_tag="ACG804_000614"
     CDS             20527..21474
                     /gene="prmA"
                     /locus_tag="ACG804_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HFS4831566.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            21475..22239
                     /locus_tag="ACG804_000615"
     CDS             21475..22239
                     /locus_tag="ACG804_000615"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HFS4831567.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            22472..24685
                     /locus_tag="ACG804_000616"
     CDS             22472..24685
                     /locus_tag="ACG804_000616"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HFS4831568.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            24696..25142
                     /gene="dtd"
                     /locus_tag="ACG804_000617"
     CDS             24696..25142
                     /gene="dtd"
                     /locus_tag="ACG804_000617"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HFS4831569.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            25313..26572
                     /locus_tag="ACG804_000618"
     CDS             25313..26572
                     /locus_tag="ACG804_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA];
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HFS4831570.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(26661..27608)
                     /locus_tag="ACG804_000619"
     CDS             complement(26661..27608)
                     /locus_tag="ACG804_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFS4831571.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            28002..29294
                     /gene="hisS"
                     /locus_tag="ACG804_000620"
     CDS             28002..29294
                     /gene="hisS"
                     /locus_tag="ACG804_000620"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HFS4831572.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            29309..31078
                     /gene="aspS"
                     /locus_tag="ACG804_000621"
     CDS             29309..31078
                     /gene="aspS"
                     /locus_tag="ACG804_000621"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HFS4831573.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            31187..32062
                     /locus_tag="ACG804_000622"
     CDS             31187..32062
                     /locus_tag="ACG804_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFS4831574.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            32328..34211
                     /locus_tag="ACG804_000623"
     CDS             32328..34211
                     /locus_tag="ACG804_000623"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFS4831575.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(34286..34570)
                     /locus_tag="ACG804_000624"
     CDS             complement(34286..34570)
                     /locus_tag="ACG804_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFS4831576.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(34560..35294)
                     /locus_tag="ACG804_000625"
     CDS             complement(34560..35294)
                     /locus_tag="ACG804_000625"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HFS4831577.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            35423..36046
                     /locus_tag="ACG804_000626"
     CDS             35423..36046
                     /locus_tag="ACG804_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HFS4831578.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            36238..37359
                     /locus_tag="ACG804_000627"
     CDS             36238..37359
                     /locus_tag="ACG804_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HFS4831579.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            37366..40494
                     /locus_tag="ACG804_000628"
     CDS             37366..40494
                     /locus_tag="ACG804_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFS4831580.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            40513..43707
                     /locus_tag="ACG804_000629"
     CDS             40513..43707
                     /locus_tag="ACG804_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HFS4831581.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(43853..44560)
                     /locus_tag="ACG804_000630"
     CDS             complement(43853..44560)
                     /locus_tag="ACG804_000630"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFS4831582.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
BASE COUNT        14521 a         7988 c         9441 g        13197 t
ORIGIN      
        1 ttttgatgaa tcagttgttt cttcagttga agattctttt gttgaatcag ttgattttgt
       61 gtcagaactc tttgttgaag ctgtagtttc acttgagtct ttcgtacttg atgaagttgt
      121 tgtgaatgca ctcaacacat tttcaaaggc atcatctttg atttttacat ttgcatcttt
      181 taattcttca ccgattactt tagttgtgaa tgcattgtca cttagtttag tttcagtagc
      241 gatatctttt agttgatctt tgtatttatc catgtcattg cctttatttt ggtttttcac
      301 cattttgaca acgtagtatt ctgtcgcata agaagtagga tttgttgtag taataacatc
      361 ggagatctca ccgtctttca atttgaaagc tgcttctttt acttctgcag gaatagttgt
      421 tgtcgttgag tcgaatttaa ctttaccgcc atcttctttt gtctctgtat cagttgattt
      481 gtctttggct aatttagaga aatcatctcc atcatccgct gattttttca catcttttgc
      541 ttcatcttca cttgataatt tgatgatttg tgcttctact tctggatgga aagatttcca
      601 agcagttttc aaatcgtcat ctgtaatatc tacgtgagct ttcaagccag cttcaaaagc
      661 taaattgtta cgaatatatt ctttataagt atctttcgta tatccagcag cttctaattg
      721 tgattcaaaa gtatcaccta atgatttcgc ttgtttgtcg tattctgcat ccacttgctt
      781 atcggttact ttatcgccat atttgttatt gaatacttta taaatgatca tccgttgtac
      841 taaggattgg ttcgatgatt caagttttgc ttcatcatag aaatcagata cagtgatcgt
      901 tccgcctttc atcgttgcga tatctttatt agtatcgcct gaacaagctg ctagagttaa
      961 aacagccaac gcactagtag ctgccaaaat aattgatttt tttttcatta aaatttgcac
     1021 tcctgtaatt agttattatt tttatatatt aactatacca tatcccattt cctttaaaaa
     1081 cgttgtcgtg gtagtttcaa acaaaattca aaatttcatc acattcctag gaaatacgca
     1141 aacttttctc acttatatag ttaaatctgt tgagaaaata atcattatta tatttgttca
     1201 ggatactctg gcagatcagc ttttagtttt tctacttgtt cattgatttg tgtgatacgt
     1261 ggttcggctt ggaatttaaa atcttcgata tcttttttga ttgcttcttg gaaagcagga
     1321 atcacagatt cagctgtttc ttttgtttcg atcaatgcgc ttttaaaatg attcaggctg
     1381 ttatttaaat catttgtcag agttgttgct tcttccaatt cttcgatcag tttctttctt
     1441 gtttcattcc cgctcctggg cgccaataac agacctccga cagtgccagc agcagctcca
     1501 aataacagtc ctttgaaaaa gtttttaatc atcgcaggac acctgcttta cgattgtttc
     1561 ttgaatagct tttagttctt ccgatccata actatcttga tgattgacaa agtgaataga
     1621 aaaatcatcc tctttgctgt agcgagggac taaatggata tgtgaatgaa aaacagattg
     1681 ataggctagt tcacggttgt tattcaagat attaagacct ttcatttctg gaaaagcttt
     1741 ttccaatgct tgagcaatct taggcacacg cgaaaaaacc tctcctgcaa gttcgggatc
     1801 atattcaaaa atatctgcta catgacgttt aggcacaact aatgtgtgtc ctttcgttgc
     1861 ttgagagatg tctaaaaaag catagacctt gtcgtcttca tatattttat agcttgggat
     1921 ttcttgattg atgattttgc aaaaaataca gttttccata taaaacatcc tttctataaa
     1981 gaataaatac ttcagcttaa ctttaccata agttaaagct attgtaagga aaaaaacaaa
     2041 ataccgtcat tttcttcgtg gtataataaa taaaaataaa tggcggagga aaaagaatga
     2101 gtttaattat cgatcatgtc acaggggggt acggacatct ccctgtgtta aaagatatca
     2161 gtttcgatgt acagcctgga gagatagtag ggttgattgg actgaacgga gcagggaaaa
     2221 gtacgaccat caagcacatt atcggtctgc tggaagcttc aaaaggaacg atagaaatca
     2281 atcatctatc cttaaagaaa aatacggaag aatatcgcaa acaaattggg tatattccag
     2341 agactccttc tttatatgaa gaattgacat tgagagaaca tatcgaagtc actgcgatgg
     2401 cctacgatat acctatggat atagcaatga aaagagcaga aaagttgttg gagacttttc
     2461 ggttatctaa tcgtcttgac tggttcccag ctaatttttc aaagggaatg aaacagaaag
     2521 tgatgatctt atgcgccttt ttgatcgagc cttctttata tatcatcgac gaaccatttt
     2581 taggcttgga tccactagct atcaatgcat tgcttgaatt gatggtagaa atgaaaaaag
     2641 aaggagccgg tattttgatg tctacgcata ttttagctac tgcagaaaaa tattgtgatc
     2701 gttttgtggt cttacataac ggagagatac gagcagacgg ttctcttgag atgttgagaa
     2761 aagaatttca gctgccggat tcttctttgg acgaaatcta tattgcttta acaaaggagc
     2821 aggcacatga gtagtttttt tcaaaaacgt ttagcaagac atcaaaagaa aatgatgaaa
     2881 tatatgcgtt atgtattgaa cgatcatttt gttttagttt gtcttttctt gattggcggt
     2941 gtgggattat attattctaa ttggttgaaa accctgcagc caccgtttgc aattggaggg
     3001 ctcataatct ctgtattttg gatgctctgt ttattcgtgg gtaagatggc tacttttgca
     3061 gaggcagcag atattgtttt tttacttcct aaagaaaaag aaatgcaaac ctatttggaa
     3121 cgagcttttc gctattcttg catttttccg ttgatctttt tgatattggc atgcggattg
     3181 gccatgccat tagtggtggt tagtacggag caatcctttt cgatgttttt cgtctatctg
     3241 atcatattat ggagtttgaa attcagtcat ctgcaaatca agagagcaga attgtttcga
     3301 ctagatcaac aagttattcg ttattggaaa ttaggctggt ttttttcttc tctgatcttt
     3361 ttgtttctat cattttattg gctaatatgg gcaggaatag caggtgcatt agtacaggca
     3421 agtctatatt actggttttt gtggaagcaa caagaaaaag gattggattg ggagaaaatg
     3481 gtgcatgtag aagaacatag gttgcatcag atctatcaat ttatcaattt attcacagat
     3541 gttcctgaaa ttacggcaaa gatcaaaaga agacgctatt tggatcctat attgactcat
     3601 attaaaagag aatcaaaaaa cacttatctt tacttgtttg caagaagatt ggcaagaggt
     3661 tctgatttta gtggtcttta tttccgatta gtaattatag gtgggttatt gattgccgga
     3721 gtagtcgact tttattttag tctgattatc ggtttcttat ttttatattt gatcggtttc
     3781 caactgttac ctttagcgaa ccagttccgc tatatggttc tcgttcagct ttatccaatc
     3841 cataagaatc agaagaagca ggcgattcag tatctactca catgggtatt aattatcgcg
     3901 tcggttattt ttggtttgat tgctgcagtc gtattagatg ggcagcagcg atgggttccg
     3961 ctagcggctt atttgattgt tactatgctc tttgttaaac tatatgtacc aactcgtttg
     4021 aagaagatgt cagactgaaa acaaagctgt gtagggtaaa aatgagaatg aaaaatagag
     4081 cgttgacagt aagaatgctg ttcgttctat tttttttgag aaaagctggt tttttgaatg
     4141 gcaattaaat gaaaaagaac gtatatgtgc ttgacgtgta gtgttcaggc gactagaata
     4201 ataagtactg caaaacaaag agtaagagga cgggagaatg catgatggag tttcagttag
     4261 accaagagtg gcggttacgt cccatcaaag gcgacacagg aaaaacatac ataggcatgc
     4321 gtgatgagga caaagtcttt attaaacgaa acacgactcc gatgttggct gctctttcaa
     4381 gggaaggaat tacaccaaaa cttgtttgga caaaacgaac ggggaatggc gatactttga
     4441 cagcacaaga gtggctggaa ggtcgcttgc tgactcctaa tgagattggt caaagaaacg
     4501 acgtgattga tgttttgtac catttacatc attcaaattc tcttaaaacc atgctgaccc
     4561 gtatcggtgg tcgtgtcatg acgccggaga agatgctgca aaaatatgaa aaagaattac
     4621 cggaagaact ccagaaaaat caatttctgc aaattgtcca tcgttttctt cgtgagcaga
     4681 tcccgtcaat agataaggaa aacttatcag tagtacacgg agatgtaaac catcgtaatt
     4741 ggttagtatg taaaaattat ttatatctag tcgattggga ttcaatcatg tttgcagacc
     4801 ctgcggtgga tattgcaacg attttaggaa attatgtgcc actgtctagc tggaatcagt
     4861 ggctgatcag ttatggcata cgcccgactg acgaaatgct tgaaaaattt cattggtatg
     4921 cggccatgaa tttgctccaa gaaatcacca gatattgcaa acgtgaagat catcgacgga
     4981 tgaacgaaga aattttacaa ttaaaacgaa ttttcagtgg ctgaggtttg gcccaaactc
     5041 tgcggagatt tggccagacc tttttaatta gaggaaagga atggagataa ataatgcgtg
     5101 tccgaaatcg tccgggagca gcggaaatgt tagcggctca cccgaatttt gtaattagtg
     5161 atccaacatt gtggaaggga aaatggaatg aattgtttga aaacgatcat ccaatccaca
     5221 ttgagattgg tatggggaaa ggccagttca tcactggaat ggcaaaagcc catcctgaaa
     5281 tcaattatat tggagtagaa atgcaggtca gtgttgtttc gattgcacta gacaagttga
     5341 tcgaacaacc gcttcctaac ctgaaacttc tacatgtgga tggatcagcg ttgacagagt
     5401 atttcgctga cagcgaagta gatcaaatct atctgaattt ttccgatcca tggccaaaaa
     5461 aacgtcatga aaaacggcga ttgacatata agacttttct tgctgtagat gaacagattc
     5521 ttcgtccaaa tggagaaatc catttcaaaa cagataatca aggattgttt gagtattctc
     5581 tggcaagttt ttctcaatat ggcatgatcc tcaaacaggt atggttagat ttacatcaaa
     5641 gtcaatttga aggcaatatt atgacggagt atgaagaaaa attttcttca aaaggtcaac
     5701 gtatttatcg agtagaagct caatttcaag ataagaccaa aaagaaaagt ctgtgaaact
     5761 aactttctgc tttcataaaa acattaatat ccataaataa atcccagaaa atgaacatta
     5821 cagatgtaat gtattttctg ggatttattt gatttaaaat gtatttattt catcggtttt
     5881 tccacaaggt ggaatcaatt ggaagcgaga aaatgaaaat aatcctttgt cggtgatctt
     5941 caattcgggt atgacagata atgttaagaa agaaagtgtc aaaaaaggat caaaggtttt
     6001 agctgctcct agttgatgtg ctttagttat taattcattc aactgttcat agacgatcga
     6061 aaaaggttcc tgtgtcatga ttccgcctat aggaagagaa acacaagcta tttcctgctg
     6121 attgttgaca acggtcatcc cgccaccttt ttgaatcaaa agattagcag catacagcat
     6181 atcctcgtcg tttgtcccaa cgacaactag attatgcgag tcatgggcaa tcgttgtcgc
     6241 tatcgctcct tgtttcagct gaaatccttt cactatgcct aatccaatgt ttcccgtttg
     6301 atggtgacgc tcgatcaccg caatctttaa ttggtctttt tcgattgaag gaatgaatcg
     6361 ttcgccttgt cggtccactt tttctaccaa atctttagtc actagactat tcgggataat
     6421 ttcgatcaca tgggcttgtg aagaagaaag aagcagctct aacgaatgtg gatttaatgg
     6481 ttgagcgttt agttttggca gacaacacgt atatgaattt gaatgatcag caaataaatg
     6541 gtcttggagt tgcccagatt gaacaactaa tgttccctta tagaaaactt catgaattgg
     6601 cagcttggta agatcgtctg ttaagaagaa atcagcttga tacccagggg caatcgcacc
     6661 tagtgttttc aaatcaaaac attctgctgc attcaatgtt gccatctgaa tggcttgtaa
     6721 tggatcgatt ccaagtgcaa tagcttgacg gacgatatga tcgattgatc cttcttttac
     6781 taaatcattg atcagtttat catcggtgac aaagaagcat cttcttgaat tttcaggtgt
     6841 gatcgccggt agtagcgatg ccagatcttt tgcaacggtc ccttctcgaa ccattaaata
     6901 cataccaaga tccaaacgtt ctttagcttc ttttgcagtt gtagcttcat gatccgtccg
     6961 aatacctgct gcaggataaa catttaactc ttccatgccg ataccagctg catgcccgtc
     7021 aatttttttc ttatgctggt gcatcaattg gatcttttct aggatgtctg tttcattatt
     7081 tgctactgct tgatagttca tgacttcagc taagcctaaa acttcgggtt tttgtaaaaa
     7141 aggggctaat ttttttgcat ttaaatttgc accattggtc tcaaaagggg ttacaggtac
     7201 acaagaaggt agcataaaaa agatattcat gagtgtttgt cttgcatctt ctatcataaa
     7261 ctcaagacct gtactcccag caatgtttcc tatttcatgg ggatctgtca ctacagtagt
     7321 aactccatga agcaaggata cttttgaaaa ttcgcttggt gataaaagtg agctttcgat
     7381 atgcacatgg ccatcgatga atcctggcac tagatattgc ccattagcat tatgtacgct
     7441 ttttccttcg tattcaccga ttcctacgat cattccttcg cagattgcta catctttttc
     7501 catgatttct ttcgtaaaga cgttgacgat cttagcatgc ttgatcacta ggtcagcagg
     7561 ctttttttta cttgctactt cgatatattt ccttaatgtt gtttccaatg gagtgcctcc
     7621 caagataaat ttttataagt ataacataaa ttcggttttt gccaatattt ttttgtaaat
     7681 tcattttatt tgaaacaaaa agatcaaaaa gacgtatgtt ttttgtggag gggagaataa
     7741 tggaaataaa acgattatcg gatcaaatga taagtgaaag ttttgccaaa catgcccaag
     7801 acgtatatat attgccagct tcagaagtat tttacatcta ttttcgctat ggaaaaaaac
     7861 gaacattctg gaagaaagtc tcttcggcag atggacagca actgatctca agatttaagt
     7921 atttgggaca gatggatatc ggagaaaaaa gaaaagctca gttaggtgca tttacttatt
     7981 ctttagaaaa acaggaagtt cgtctgcggt tgtcttctgt aggagattac cttcaacgag
     8041 agagtttagt gattcggcta ttatacggta cttttgaaac accccatcgt tgctttagtt
     8101 ctcgagattt tgcaactatt ttacagaaaa ccgtcagacg tggattatac cttttcagcg
     8161 gaccagtcgg atcaggcaag acttctctaa tgtatcggtt ggctttggaa gaaaaattgc
     8221 aagtgattac tatcgaagat cctgtagaga tagaagaacc gttttttctg cagctacaga
     8281 tcaatccgaa aatagcacag acttatgata cacttttgag actcgcatta cggcatcgtc
     8341 cagacttgct aatcattggc gagataagag atgaatcaac tgcacatgct gcggtaagag
     8401 cagcactaac agggcaccgg gtttttgcaa ccgtacatgc acgcaatctt gaaggtacat
     8461 tggtcagaat ccatgaactg acaaagaaaa aagaagagct atctgaatgt ttagctggtg
     8521 tcatttatca agaacttttg gaagatgcca atcaccatcc ttctgtttta tggagttatc
     8581 aatttatgga ggaagaatca gtaaaaaaat catgggagga aagttatgaa gaagctcagg
     8641 aaaatatttg gcagtcagaa ctattctaaa ggattaacaa gaagccagca aaaccagttt
     8701 gcacaaacca tgggagaact gcttttatct ggttttagtc tgcaagaatc cctttattta
     8761 ttactcacga tccgttcgtt tccacctgtt attttggcaa atatccaaca tcagctaaag
     8821 gaagggcaag cgtttagtga ggtactttcg caaataggat atggagcaga gcaactggta
     8881 cagatcgagt tagctgaacg tcatgggaat ctgccgacaa ctttgttgga aattgccaaa
     8941 cagtttcggc ttgttgaagg atttcgcaat gatttgaaaa agctgcttgc atatccgatg
     9001 ctattgctca cctttttgct aggtatcttg tttagtatgc ggttgttcgt tttgcctcag
     9061 cttattggtt caggaatggt catgcaagag cattggggta ttcagctgat acaagtcttt
     9121 cattggtatg ttctactatt catcctagcg gttactctat tggctttact agtaaggtat
     9181 cgtctgatga agttgtctcc tgttgatcag agtgaatgga taagcagaca attattgatt
     9241 ggaccgatat attccttgta tcaatcggct tatttgtcac tagagattgg aaagcttttt
     9301 catgaaggtt tcgaattaag gcaaatcata gtctgcttaa aggaaacgaa acaagaaagt
     9361 ctgattcagc atcttgcctc taagttgatt caaggattgg aggcaggtat gtcattggct
     9421 gagcagttcc agaattatcg ttttctatca gaagaattca gtaaaattgt tttacaggga
     9481 gaggcaaagg gaagtttagg taaagaactg attttttaca gcgaatggac aagaaaacag
     9541 cttttcaaac gtcttcatca ctggatgcat tttattcagc caatcatttt tttgggcgta
     9601 gcggctttga ttttattagt ttatgccgct gttttattac ctgtttacgg aagcatagag
     9661 gaggttttgc catgaaaaag agaaaaatat cttattatag cggttttaca ttgatcgaaa
     9721 tgctaatcgt cttactgatc atcagtgtat tagtgttgtt gttcgtccct aatttgtcgc
     9781 gttataggaa tcatgtagac caagaaagtc gtgaagcgat catccagttg gtagacacac
     9841 aaaaagagct ctatgcgctt caaaataatg gaagagttcc tactgtggag gaattgttga
     9901 atgaaggcta tatcaaacga gaacatgcag aaatctatca gcggccttga aggtaaggtt
     9961 ttagcatcag gatatacgtt gtttgaatca ctcttactga ttttattact tacaacgatc
    10021 ctttcttttc cagttctcgc attttctgca tggaagaatg aattggcagt ctatcaattt
    10081 ttcggccaat ttgaaaaacg aatctattct acgcaaaaaa tcgctattgt gaatcagatc
    10141 caaacaggct tttattggaa tagtgaagag aatcaaatca tttttcatgt tccgaatcca
    10201 gataaaataa attgggaagt attagatatt cctgatgaga ttaccttgaa acgccatgct
    10261 tctattactt ttgctgctag aaccgggaat gaaagttcac taaaagctta tcaattttat
    10321 tgggaagaaa aagagcggac gattacgtat caattccaga tagggagtgg tcgctataca
    10381 aaaagaattg aataaaacag gatttgtttt gttggagtcc cttacagcgc ttatgatcgc
    10441 ttctgtctgt gtctacttag tgagctttgg ccagctgttt ttgcttcagg cagaaaagaa
    10501 aagtggggag gaactgctat ttattcgaat gatttatgaa gatatcaaga cgcagcggat
    10561 gtatcacaaa agaccagagc gaagggaaga aatgatccca tacgatatcc aaattgtcga
    10621 taataatgga gtaatcgaaa aagtgtttgt caatatggag aaagaagcga tcagtattga
    10681 aaaaacaagt aattccagca tttacgctga ttgaatgtct aattggactg atgatattga
    10741 gcagtctatt gctcacattc aatcttttga ttcagcaaac catccaagta agtgaatttt
    10801 tgcagcgtaa agatcaaaaa gagtggctaa tatttttagc acaattagaa gaagaactca
    10861 agagcagtca caatgtctct gtgaaaaatc agcaactgca ctacacgatc gaggataaac
    10921 agtatatcat cgaaagatat caggcaatga tacgtaaaag aagaacttcc ggcggacatc
    10981 aacctatgtt aacaagtatc actgagcttc aattattgga aaaagaacac acaatttctt
    11041 tttatgtaca ctttgaaaat ggagaagatg gatatgccat atggacaaaa aacgatcagt
    11101 agaaaatgtt ataagggctc tattttattt tctgtcttgc ttttatttct tttatgtacg
    11161 tttttattga tggcagcatt agaaagctac cgtttgtcaa tggatcttaa tatacgaatc
    11221 aaaaattatt atatagcaaa aataatgaag cagatggctt tatcggaaca gtctacgctt
    11281 gccgaaagtt cggaaggagt tttttactac acaactggat ctgtaacata tcagtgggta
    11341 caacagtccc tattcttaga ggtggaagtc tcaccgttta tctttcggtt cacagaagaa
    11401 gtaaaaaatg atacagatac tagtacagaa tgatggaatg ttcgtgaaaa cgccctcttt
    11461 tctgttataa cactgttttt aataaaaaaa tgtttgccgt ttcacaaata aaaaacagtg
    11521 aaaacgattg aaattttgtc aattgttcga tagaattaaa caggtgaaaa aattgttata
    11581 atatatctag aaatgaggtg caccatgtta ccagaaaaaa tggaacaagg gtttaatcaa
    11641 aacctggaag ctattcagct tttacagaat gcattgggaa cttccttttt agaagcctat
    11701 gtcgaaaatg cagaaaattt aatagatgat tatcaagtac gtgtggtgga tggagtgccg
    11761 acaaaagaga caacgcaacg gatcacagct ctttatgaag agttgaagaa actttctttc
    11821 gagccagaag aatggcgcag actgtctcaa ttacttttat tgaagggcag ccagacagaa
    11881 catttgcagg cgaaccatca actcactcct gatagtatcg gttttttatt tgtttttctt
    11941 attgaacaac tatacacaaa taaaaaagca ccggttaaga ttctggatat tgcggcagga
    12001 atgggcaact tgttattaac agttctttta aacctatcga atgcggggta ccaaacagaa
    12061 ggaattggtg tggatattga tgatacattg ttggctgtcg cagcttctac aagtgatttg
    12121 acacaagcaa atgttcaata ctttcatcaa gacgggttgc aggaattatt aatagatcct
    12181 gtcgattttg caatcagcga tttgccaatc ggttattatc cgaatgacga aaaagcaaaa
    12241 gagtttttaa caagtaccga agaaggccat agttatgcac atcatttatt gctagagcaa
    12301 tcaatgaaat atgtgaagcc ggatggtttt ggtttgtttt tgatgccgag tggattttta
    12361 gaaacggatc aaagtgaaga aatcaaaaaa tggtttaaag aagaaggtta tcttcaagga
    12421 atgattcaat tgccagatga attgttccgt aataaacaat cgcaaaaaag tattttgatc
    12481 ttacagaaaa aaggaccaca agcacaacaa gtaaaagaag tcttgcttgt gaaacttgct
    12541 tcattaaaag aaccagagaa ggtgacggaa tttttcaacg agtttaaaaa ctggaaatca
    12601 tctgctctgt aatcattcaa cgagaaggag agtcatatgt ctaaaacaat tgcaatcaat
    12661 gctgggagtt caagtttgaa atggcaatta tatcaaatgc cagaagaaac cgtagttgcg
    12721 aaagggatcg tcgaacgtat cggtttacaa gattctattt ttaccatcaa gtacggcgat
    12781 aatcaaaaat tcgaacaaat catggatatc gaaaaccacg aagtagcagt aaaaatgctg
    12841 ttagatcagt tgattgaact gcaaatttta agctcttatg atgaaatcac cggagtaggg
    12901 caccgtgttg ttcacggagg agaaacttat ggggattcag tagtgatcga tgagaaagta
    12961 atggaccgca ttgctgaatt agcagaattt gctcctttgc ataatcctgc aaacttaatg
    13021 gggatcaaag cgtttaaaaa gattttacct gacattttga gtgtggctgt attcgataca
    13081 tctttccact caacaatgcc aaagcaaaat tatttatata gcttaccggt gtcttattat
    13141 gaagatttca aagtaagaaa atatggcttc catggcacaa gtcatcgtta tgtgtcggaa
    13201 cgtgcggcaa aattattgaa caaaccgatc gaagaactaa aaatcatcac ttgccactta
    13261 ggaaatggtg tatcgatcac agcagtcgat ggaggtaaat ccatggatac ttctatggga
    13321 ttcacaccat tagctggggt gacaatgggt acacgttcag gtgatatcga tccagctgtt
    13381 ctcccatatt taatggaaaa attagagatt gatattgatg aaatgatcaa tgttttgaac
    13441 aagaaatctg gtctgctagg cctaacagga ttgtctagtg atatgcgtga tcttgaaaag
    13501 aactatgaaa aagaacatat tcgtttagct tatgacattt tcgtggaccg catccgaaaa
    13561 tacatcggcg gttatgtgac aacgatgaat ggtgttgatg caattgtctt tactgctggt
    13621 atcggcgaga atgacggaca tgtacgtagt gaaatcatca aaggtatgtc ttggtttggt
    13681 tgtgaaatcg atccagcgtt gaatgaattg cgtggtgaag aagtagatat ctctacaaaa
    13741 gaatcaaaag taagagtatt agtgatccca acagatgagg aactaatgat tgcccgtgat
    13801 gtggagcgtc tgcgcggcta agccaaagca ttcgttagga taaaagatga aacgcatgca
    13861 agagggaatt cttgcatgtg ttttttttgc ggagaagacc gcaaaatggt aatttaactt
    13921 caatttccct tcttttttac aggatcttct tagggaattt tgcttggaaa agtggtcaaa
    13981 agggaaaaga ctggcatttt atttattgat tttcaggaaa atcccaatat tttattttca
    14041 ttcatcttta taagggacat tacatatgta aaaagaaaaa acatttttag atcagcctcg
    14101 tgggctgtcg actttattct tcgctttatg tttagctaga aaaccgatcc gaaacattca
    14161 ttgatcgaat aataaaaact tgattttcca cctgtacttt gcctgaatcg tgaaagcaca
    14221 ggtatgaaaa tcaagttttt tgttgcgaaa aaacgtccta gtcaatcagt tggccgagcg
    14281 gctggcggct gatctgctcc tgatcaataa cgagtgcttc ttggaagtgt tgctgcaaaa
    14341 agtagcggtc atggctgact gctaggagcg ttccttgata gtcttgcagc atttcttcaa
    14401 tttcttctcg agcatagctg tcgaggtgat tggttggttc atccaaaatc aggacgttga
    14461 ttttttctaa aaagagtttc agcaacgcca aacggatttt ttcaccaccg gataaatctt
    14521 tgatccgttt acccacatcg ctttgataaa agccactttt ggctaattgc cgtcgagcga
    14581 cttcttcgtt tccagtcaat gtgatggcgt aagccagcaa acggctatcg ggatcggcaa
    14641 actgcagctg ctgcggcaaa taaccgattt gcaagctact acctaatttg atggtgccac
    14701 cgtaaggctt ttcctcaccg agtaataatt tgagtaaggt tgattttcct gcaccattgt
    14761 cgccgatgat ggctaaatga tctccacgat agactgcaaa actgctgtct ttgaatagta
    14821 cttgatcagc gtactgctgg tgcaagtttt gaatgatgaa aacttctttg ccagattttc
    14881 caccattaga caagctttgc agccgatttt tcgggggagg tggcggtttg acgagtgtca
    14941 gtttcgccag gcggcgttcc agttctttgg cttttttgaa gaaggactca ttgtctcctt
    15001 catgtgccca ctgacgaaaa cgacgaatca tgactttcaa ccgctggact tctttttgct
    15061 gcagttcgta attttttgtc agctcagcca agcgagcttc tttcaagact cgaaaacggc
    15121 tgtagtttcc gggatactca atcaatgcac cttcttccag ttcccatgtt tttgtggtga
    15181 cttgatcgag aaattgccga tcatgagaaa cgaccagaac cgattttttt gtattctgta
    15241 aatagttttc caaccagcga atactgttaa gatctaaatg attggtcggt tcatcgagta
    15301 aaagtaaatc ggcatcggct gctaaaattt tggctaaagc gactttaact cgttcgcctc
    15361 cgctaagttc tgttaaccgt gcttcctgac ggtgtggaat ccctaagcct tgcaagatcg
    15421 ctgcaatccg gtcttctaat acgtaaccgc ctagttcttc aaagcgatgc tgcagctcac
    15481 cgtaacgggc cagacacttc tctaagtttg tatctggttc tgtcatcaat gcttcgtagc
    15541 gactcatttg ctgtttgagg tcctgtatct cagcggcaga atggagcaag tagtggttga
    15601 cggtcgcttc ggaaactgta agttcttgtt cgaccgtccc gatctttaag ccttttttgc
    15661 gactgataac accgctgtcg acaccttctc tgccggtcaa gatttgtaaa aaggttgatt
    15721 tgccagttcc gttgataccg actaaggcaa ttttttcacc agcttcaatt tgacaggata
    15781 aatcctcaaa taatggattc ccgccgattg tttttttaat agaaattgct tgtatgatca
    15841 tgatctctct ccttgagacc actcaaaaag gccatggtta tccatggcct gtgttattta
    15901 aactcagatt atcatgagaa aaataccttg agatggccat tgattttacg tgaattcaac
    15961 tgttttggac aaacttgtcc cgtcaacagc aactgtaaaa ccaattgcat ggctaaatgc
    16021 gatatggtat cgttggtaat tttcattact tgttatttta gtcatgcgca tcatagtatt
    16081 ttccctcctt cgtgtagttg tcttttccag tgtacctgaa agtgtcagaa agttcaacta
    16141 gcgctgacat ttacttaata tttatcgatg tgtaattctg tcagagagct ttttttatct
    16201 gactgagggt aatgtctcgt ggaccacatc attgtattct gagctaaacc agcgttcagg
    16261 cgaaatcata tggtgtttga taaaaaactt tgtctacatg acttcctttt gccatttgct
    16321 taataccgtt gcattaaaca gctcttctct ttggaaatct caccaacatc gcgttcagga
    16381 gtatcgttgt ggttgcaatg gcaagcggta gcctttcatc aattcttgaa tgatttaccg
    16441 aatgtagcac ttgccttctc gcggtacccg aacccgaaat aaaattttag tttggcgata
    16501 aaatcggtat ccgccatcga tacttcatat tttttcgtat cagattcatc ggaaacttcc
    16561 acattgacga accaataagc tttggcatgc ttaggtcgtt ttaaaccaca ccagggcgac
    16621 taatcgccct ggtgttcact tttttttatt ttacttgaac tcattgactg ttttcccttt
    16681 attttaaaca ttataaagac cgatgagtgc ttgccgcgtc ttttgttttt atcacggttt
    16741 tttgtgcaaa aaaacctgcc gatagttggc aggtcgtcta cgtgttaagc tttggtgtgg
    16801 tctttagctg gcaattggtt ttctaaatca gttcggacaa caagcacatc gcaagctgcg
    16861 tttctaataa catattcaga aacagaacca ataaataaac gttctacagc attcaatcct
    16921 gtggctccta acataatcaa atctacttga ttatcttctg ggatttctct ggcaataatt
    16981 tgttttggtg agccatattc tacgacagag gttacattat tcaagccagc tttcttcgca
    17041 ttgctttcat aatctgccaa tgtttgcttt gccatttcag tagcttgttc tgcaagcatt
    17101 ccatcaaagg atgaaacggt ttggaaagaa cgtgtgtcaa tgacatgtgc taatagaagt
    17161 tctccgttat ttcggatagc tacattgacc gcctttttaa aagctaattc agcttcatca
    17221 gaaccatcta cggcaaccat gatttttttg tattgttgta acataagcat tcactcctca
    17281 agtcaatcgt attgtactct tttattgtag aacactttag ggaaaaagag aattatttac
    17341 tgctttggtt cagcaatttt ttttgcaaat cggatactga aggtggcaga aacaataatt
    17401 acgatcagta aaaagaccaa ggcaataaag cgttgattga aaaaagctgt taaaataccc
    17461 attacgccta aaacagcata tgcagctccg taaaattgta ggaatccttg atttttatca
    17521 tttttgttga tcaatacaaa aaagatatcc tgtttattaa ataaataata gctaacgaat
    17581 aataatacta aagtggcgat aatcattaaa atcctaatca tgaacaaatc ctccaaaata
    17641 agcaacaaat agaaaaagca atttgccaag agcaaattgc tttattcttt aaaagatggt
    17701 aatctccgtt aatgccgttg tttgtcctgt agtattgatc ccgcgaattc aagcaggtgg
    17761 gtcccatggt cgtagcttcg aactaccaaa tgataaggca tgttaccagc agtgacacaa
    17821 gacgggtccc aagatatcaa taaaaatgtt cggtcaacac acaaagagga caattcgaac
    17881 atcacagatt tcccacctct atagtagcat atgaatttaa aaagagcaat gagagagctc
    17941 gcagaaacag aaccgttttc ttgtctagtt ttttggagga tgctttttcc actcttttat
    18001 acggtaatac tgttgaccca gagcctgttc atatttccct gtatcttttg gctgataata
    18061 ctgagcattc ttcagtttat ctggtaaata ttgctgattg acccaagcct gatcaaaatg
    18121 atgaggatac tgataaccca cgccacggtt gagtgatttc gcacctttgt aatggctatc
    18181 tctcaaatga tcaggaacat ctccagcttt gccctctcga atatcagcaa gtgctgcatc
    18241 taatgccatg taggcagaat tggattttgg cgacaagcaa agatcgacga cgacgtctgc
    18301 tagtgggata cgtgcctcag gcaatcccaa tttttcagca gctaatacag cgttcactgt
    18361 acgagccgca gcagcaggat tacctaaacc tatatcttca taaccgataa ccatcagacg
    18421 ccggcaaata cttgccagat cacctgcctc aactaaacgg gcgagataat gaagtgcagc
    18481 atccacatca cttccacgaa tcgatttttg aaaagccgaa ataacgtcat aatgagcatc
    18541 tccatttttg tcatgggtaa gagcttttct ttggacacat tcttcaatga tcgacagtgt
    18601 aagatgaatc cttccttctt tatctgaagg agtcgatagt gtagccagtt ccagcccatt
    18661 caatgcactc cgcaaatcgc cgttcgttgc acgcgaaagg tgaagaagag catcttcgtc
    18721 taactggatt gcttgttgtc caaggccgcg ttctttatcc cttaaagcat gttcgactgc
    18781 caactggatg tcttgttctg ttaatggttt gacttcaaag atctgtgtac ggctgcggat
    18841 cgctggattg atggtaatat aaggattctc agtagtcgct ccgatcaaga tgattcggcc
    18901 actttctaaa tgaggaagca gaaaatcctg ttttgtttta tctaatcggt gtacttcatc
    18961 caataagagg atcactgtac cactcatttt tgcttcttcc gctacaactt gtagatcctt
    19021 ttttgaatct gtagcggcgt ttagcatgcg aaatgcataa ttagtagagc cggcgatcgc
    19081 acttgcgata ctcgtttttc cagtaccagg aggtccatat agaatcatgg aagagagcat
    19141 gcgagcatcg accatgcggc gtatgatttt tccttccccg actagatgct gctgaccaac
    19201 gacttcatcg atcgttcgag gtctcatgcg ataagccaat ggctgttgca taggattttc
    19261 ctccttcttg tttttacgtc ccttaattat atcatattta gcaagatgcc tagaaagaac
    19321 agccttctgt tgttttgttt tcatagctta tccaactaat attgtgtatg ataaagtagg
    19381 tgagaaaaat gacggataaa caaaagatag atgaattttt ttggaataaa acgacgccag
    19441 aagtggcacg ggatttattg gggatgtatt tggagcatga cacaccagaa ggaagattag
    19501 ctggatatat tgtagacgcg gaagcatacc taggtccaga agacgaggcc gcccatagct
    19561 atggtttaag aagaacaccg cgtgtgcggg caatgtatga aaaaccaggt acgatctacc
    19621 tttacacgat gcatactcat cggattttga acatcattac tcagccagaa gggattcctc
    19681 aaggagtaat gatacgtgca atcgaacccg ccgcaatgat tgatcaaatg agtaaaaatc
    19741 gtggcggaaa aactggtcca gatatcagca acggtccggg aaaattagtg gaagcattag
    19801 caattcctca agaactttat ggtcagtcta tagcagatag ttcgttacgc ttagtttttg
    19861 agaaaaaaaa gacaccaaaa aagatcaatg ctttgcctag aatcggtatc ccaaacaaag
    19921 gtgtatggac agaaaagccg ttgcgttttg ttgtgtcggg aaatccttat atctctttac
    19981 aaagaaaaaa ccaaatcgag aaagattggg gttggaggaa agaaaatgaa aaagaaggat
    20041 ctattaacat atttagatga aataattgaa aaacaagtga cagactatga tgtagcttta
    20101 gattgggata caaaaaatca tacgatcgag atcgttgttc gcttgtttgc agaaaataaa
    20161 gcacaatttg agattgatga tgcagaaggg atcgtttcgc aagaaccaat tatcgaattt
    20221 gaagacggcg tacttctttt taatcctcag aaatctgttt ttgatgaacg caattatcta
    20281 gcagtaatcc cttatgaagg aaaaaaaggg ttggcaaaat cagtagctga ttctttagtg
    20341 gaatatctaa atgaagtatt agctcaaggg caaagcgatt tgcttgattt tttggatgaa
    20401 gacgatgacg aagctgtatt cgagcttcac tgggataatc agcaactagc agaattagta
    20461 gaagtaaaac agcaaaatga agcagatact tatttaccgt acccaagtta ttaaggagtg
    20521 acagatatga aatggaatga agtaaaagta gaaactgaaa gtgaagcagt cgaagcagtt
    20581 gctaatattt tgatggaggc aggggcgagt ggtgtcgcga ttgaagattc tttagatgtt
    20641 gaacattttc agtcggatca atatggtgag attttagata aaaatgattt tacatcgctg
    20701 aaagaaggcg cactagtcat ggcttatttt ccggaaacga ctttcttacc ggaaatcttg
    20761 ccttttatca aagatcgtat cacacaatta cctgagtttg gtctagctat tggaaaaaat
    20821 aaagtaacag ttagtgaagt agaggaaagc aactgggcaa cagcctggaa gaaatactat
    20881 catccggtgc gtattacgcg aatgctgacg gttgcgccaa gctgggaaaa ctaccagaca
    20941 gaagatcctc tagaaaaaat tatcacacta gatcctggta tggcatttgg cacaggcact
    21001 catcccacga cttccttgac attgacagca ctagaaacag tcttgcgtgg tggtgaaaca
    21061 ttgctagatg tgggaactgg gtcgggcgtg ctaagtattg cagcaaaata tcttggtgca
    21121 aaagatgtct atgcctttga tttagacgaa gtagccgttc gttcggcgaa agaaaatatg
    21181 gatatgaatg aaatagccaa agatgtccat gtatcagcta acgatctttt gacaggaatc
    21241 gagattgaaa gtgatgtaat cgttgcgaac attttagcag atatcatctt attgatgatc
    21301 ccagatgctt ggcgtttact gaagcaaaca ggcacgctga tcgtttcagg aatcattgaa
    21361 gagaagaagc aaatggttct ggatgccatg ttagaacaag ggtttatcgt ggatcaaatt
    21421 ttccagcaaa aagactggta tgcaattatt ttgaaaaaac cagaggtgga atagatgcag
    21481 cggtattttt taaaagaatc atatgaatca aaagactatt ttgttttaga aggggaaaac
    21541 tatcaccaca ttgtacgggt tatgaggatg gaacccgagg atgaagtttt tttggcattc
    21601 aatgatcaaa tagccattgt tgcagaaatc acggagatta ctgaagaggc tgtttatctg
    21661 aaagaaatta aaaaagaaga aaatcaaaag gaactgccaa gttcgattac catagcgagt
    21721 ggctatccta aaggggaaaa gctggattgg atcgttcaga aatccactga attaggagcg
    21781 caagcttttc ttggtttccc ggcatcagcc tctgtcgtta aatgggatgc aaaaaaacgt
    21841 atgaaacgac aacaacggct tgaaaagatt gctcaagagg cagcggaaca atcccatcgg
    21901 cagatcgtgc catcagtaga gttattggaa acgaaacaag atttatttga gcggctagat
    21961 gattatgacg tggtcttggt tgcttatgag gaatcagcaa agcaaggcga aaaatcaaat
    22021 gcagccaaaa ttcttagtga aacaaaacca gatagtcgaa tcttagctgt ctttggacca
    22081 gaaggtggat tatcccgcga tgaagtcgat tattttgtag aacacaaagg gatactttgt
    22141 ggattaggac caagaatcct tcgtacagaa acagcacctc tttatttatt aagtgctgct
    22201 agctatcaat gggaattaat gaatccttct ttcagctaac gttcttcatt aataaaagag
    22261 tatcgacaga aagaattgaa aaaatagtca acaatttgta taatagaaac aattatttat
    22321 acaatggata cgaaaaatcg tttgaaaaag cttttaaaaa gcgaacattt ccgtaaaaaa
    22381 acgtataact gcacggattt tgggacaatt atcaaacaga tatttgtccc gattcccgtt
    22441 ttaccgaaaa aagaaagggg gatcgattcc tgtgacaaaa gaagaaattt taacgggacc
    22501 cggtgtcata aagctcgtta gtcaatacat gggtcccgaa catgtagcat ttgttgagaa
    22561 agcatgcgaa tacgcgactg ctgcacatga cggacagttt agaaaatcag gcgaacccta
    22621 cattattcat cctatccaag tcgcaggtat attagcagat ttaaaaatgg atccccatac
    22681 agtggctaca ggcttcttac atgatgttgt tgaagataca gaaatcactt tagaagatct
    22741 gagagaagaa tttggcgatg acgttgctat gttagtggac ggcgtaacca aattagggaa
    22801 aataaaatat aaatcccacg aagagcagct agcagaaaac caccgaaaga tgctgctagc
    22861 aatggctcaa gatttacgag ttatcatggt caaattagct gatagactac ataacatgcg
    22921 tacgttgaag cacctgcgag aagataagca aagaaggatc gctcaggaaa ctttagaaat
    22981 ctatgcgcct cttgcacatc gtctagggat cagccggatc aaatgggaat tagaagatac
    23041 agcacttcgt tatctaaatc caaaacagta ttaccgtatc gtccacttga tgcagacgaa
    23101 gagagaagaa cgtgaaaaat acgtaagtgg tactgttgaa gatattcgaa tagcgacaga
    23161 agagctgggg atttttgcag aaatctatgg acggccaaaa cacatttatt caatctatcg
    23221 taaaatgaaa gatcagaaaa agcagttcaa cgaaatttat gacttgctag ctattcgagt
    23281 gatcgtagat tcaatcaagg attgttatgc tgtattagga gcaatccaca caaaatggaa
    23341 accaatgccc ggcagattta aggattatat tgccatgcca aaagctaata tgtaccaatc
    23401 tttgcatact accgtgatcg gtccggcagg aaatccggta gaaattcaaa tccgaacaca
    23461 ggaaatgcat gaaatcgctg aattcggggt tgctgcacac tgggcctata aagaaggaaa
    23521 aaatgaaaaa gtagaaccag atggtatgac gaaacaatta agctggttcc atgagatact
    23581 cgaacttcaa gacgaaagct atgatgcttc tgaatttatg gaaggcgtaa aaggagatat
    23641 ctttagtgat aaagtctacg tcttcacacc aaaaggagac gttactgagt taccaaaagg
    23701 atccggacca ttggactttg catacagtat ccatacagat atcggtaaca aaaccactgg
    23761 tgcaaaagta aatggcaaaa tggtgcagct tgattacaaa ttgaaaaacg gagatatcat
    23821 tgagatcatg acttctccaa attcatttgg cccaagtcgc gactggttga aattagttgc
    23881 tactagcaaa gcaagaaata agatcaaacg tttcttcaaa gcccaagatc gagaagaaaa
    23941 tgtgatcaaa ggccacgaat ccgtggtcaa atgtattaca gatctaggat ttacgcctaa
    24001 agatattttg acgaagaaca aactgcaaga agcactcgat cgttttaatt atcaaacaga
    24061 agatgatctc tatgcagctg tagggtatgg agaagttagc cccttgacga tggccaatcg
    24121 tctgactgaa aaagaacgta aagaacaaaa aatcgagcag caaaagcaag aagcagaaga
    24181 aatcatgaat cagccgaaaa aagaacctga caaaatgaaa gtacgtcatg aaggtggcgt
    24241 tgtcattcaa ggggtagaaa acttactaat tcgtatcagt cgctgctgta atccgattcc
    24301 tggtgatgat atcgttggtt atatcactaa aggcagaggg atatccattc atcgtcgaga
    24361 ttgtccgaat gttcagcctg acaaaccaaa tgtagcagaa cgtttgattg aagtcgaatg
    24421 ggaagataca tcgaatacac gaaaagagta tgatgcagat ttggaaattt acggctataa
    24481 tcgttcaggc ttattgaatg atgtacttca aacagtcaat gcgctaacga aaaatctcaa
    24541 cagcgttgaa gcacggacga ataaagataa aatggcgacg atccatttga cggttggtat
    24601 ccagaattta tcccacctaa agagtatcgt ggataaaatc aaagcagtac ctgatgtcta
    24661 cagtgtacgc cggacgaatg gataggagga cagatatgag agcagttgtt caacgggtaa
    24721 gtaaagctgc tgtgtcagtc gatcagcaag aaattggaaa aattggctac ggcctacttg
    24781 ttttattagg cattcatgaa accgatacgc aaaaagatgt ggactatctg gtaaaaaaaa
    24841 ttgcacaaat gcgtattttt gaagatgaac aaggaaaaat gaatattagt gtagaagatg
    24901 tgggaggaca aattttaagt atctctcaat tcacactgtt tgcggatacg aaaaaaggaa
    24961 atcgaccaag ctttgtggaa gccgcacgac cagaaacagc tattccttta tacgaatcat
    25021 tcaatgaagg aatcagaagt cgcggcatca cagtcgctac cggacaattc ggagcagata
    25081 tgtcggtttc tctcgtcaat gatggacctg taacgatcat tattgattct aaaaacaaat
    25141 aaagtaatct ggttttcact agtaaaaact atgaaacacg tcgcttaagt tagactgata
    25201 aactctaact taagtggctt ttttgtctgc aaaaagcgct tcttttgtca gcagtcggaa
    25261 aaaaagttaa gcttaaatta tacaagttat tttttatagg aggttgctga agatgaaaga
    25321 agtaccagta gtagatatca aaatcacaga tttaaaaaaa ttgtatcaaa aaggatacaa
    25381 catgttggag gagttacgcc atgaagcgga cgctcccgtc gtcaaagcaa agattttcaa
    25441 taaagaagct atcacgatct acggatcatc agcagcaaaa gtattttatg atccaaggaa
    25501 tttcaaacga aaaggtgcta tgccaaaatt agtattgaag acactttttg gtcaaggtgg
    25561 agtacagact ttggatggag ctgctcatca ccatcggaaa aatattttta tggatctaat
    25621 gacaccggaa agaatggaag attatcatcg tatcttagat aagaatctga cacaagcact
    25681 tgaagcacag catggtcaat ttgaactatt tgatttaagt aagatggttt tctttacatc
    25741 tatttgcgag tgggcaggta tcaatttatc agcgatttct aaagatgagg tcgaaaaatt
    25801 agcagaatat caaatctcta tgatcagcgg aacgtttact tctccgattg atcacataaa
    25861 aggtgtcgag aatcgcaaaa aatcagaaaa atgggcgcaa ggcttgattg aagaagctcg
    25921 acaaaatcct gtggctggaa aagaaaatgt ggcattatat gcttttgcca atgccacaga
    25981 tttagatggt cagcttttac ctctggaagt ggcagctgtt gaattattga acatcatccg
    26041 tccaacggtt gctctaactg tgtgggcggc attgatggga catgcacttt tcagtagacc
    26101 agatttgtat cagcaattaa aaaatgactt ttcgacgtta caagatccgt ttattcaaga
    26161 aatgagacgc tattatcctt tcttcccaat gctacctgcg atttcgctga aagaagtaga
    26221 agtagatggt tatcgtatac cagaaggcag ttgggttatt ttagatttat atggaacaga
    26281 ccatgatgaa cgaacagttg aagcgccaga ttcctttatg atcaaacggt atgtagggaa
    26341 agcaaaagat atttcctata aagaagaata tgagatgatt gcacaaggcg ggggaaattt
    26401 tcgacaaatg catcgctgtg caggagaatg gatcactctt catagtctac gtgtgttttc
    26461 cgatcagcta gtaaataagt ttgagttctc tgtacctgaa caagattgga cgattccatt
    26521 caatcagttt ccgacttatc cgaatagccg agcgctactt tacaagaatt agattagcat
    26581 aaacttatcg aaaaaaagga agatcaaaca gtgctgatct tccttttttc atattactat
    26641 aaattgataa ggtcaattga tcaaaatcca cgaaatgctt catcaatggt ttgataatct
    26701 tcattggata aatgcaaatc taaagcttgg acattgtcag atacttgctc tggacgctta
    26761 gctccaggta taactacaga cactcgtgga ttcttcatgt accaagctaa aacaagttgc
    26821 gcaggagtgg cttggtatct tttagcaatg gggcgaagta catcgacagc ggttaaaatt
    26881 tctctgaaac gttctccttg gaaatctgga tttctttttc gaggatctcc ttcaccaaat
    26941 tgtttttcct caccaagttc atattttcct gtcagcaaac cggaagcaag aggaaaatag
    27001 ggaacaaaac tgattttgtt tttttcaaga taagggaata attctttttc agcctgccga
    27061 tggatcaaac tgtatttatc ttctactaca tcgacatatc catctgcatt cgcttctttc
    27121 aattgttcta acgtgaagtt tgacacaccg actgctcgga tttttcctgc ttcttttaat
    27181 tcgtgcaatg tagcaactga ttcatttttt ggtgtgcttt catccggaaa gtggatataa
    27241 aaaatgtcga tgtaatcagt ttgcagacgt tttagtgcat cttccaccga ttgtttgaga
    27301 aactcaggag aattatcaaa tgttcgccct ttatttggta catgagcagc ttttgtagcg
    27361 atgacgacac gtgagcgatc atattctttt tccttcagta cctcgccaat cagttcttcg
    27421 gaacggccgt ttccgtaagc ataagcggta tcgatcaaat tgatcccgct attcaaagct
    27481 gtacgaacta cttgttttcc tgtctcatct tccaaaccgt caaaaagatt atgtcctcca
    27541 acggcatttg ctcctaatcc aagctgttct gcgtagactt gtgaatgtcc gattcttatt
    27601 tctgccatag ctgattcctc ctttttgtct agtctaaaac aaaataccaa aaagctgaac
    27661 taaaacgttt ttgtgagggg aaatagtcag atatctcttg actttgagac tggtttttag
    27721 taggttataa gtaatatcga atgtcaatga aagagcgagt aagtttttga aactttacaa
    27781 gagaggatca tcgaggctga aaatgatcta aagtttcatt agcctaaaga cactctggag
    27841 atggacgagt gaaaagccgt cccgcgtacg agcgttattc gtaagaggaa agagaaatct
    27901 ttcaaaatta ggtggtaccg tgtatgaatt tcattcaccc ttgttcatga tgaacaaggg
    27961 tgattttttt atttacatag ctaagaaagg gagagaaaac tatgagtttc caaagaccaa
    28021 aaggaacaaa tgatattttg ccaggcgaat cagaaaaatg gcagtttgtc gaagaaacag
    28081 cacgtttatt attcagagat tatcagtata atgaaatgcg tacaccgatt tttgaacact
    28141 atgaagtgat atcccgaagt gtaggggata caacggatat cgtttcaaaa gagatgtatg
    28201 atttttatga caaaggggaa cgccatgtga cgcttcgacc agaaggtaca gcaccaatcg
    28261 ttcgttcttt tgttgagcat aaattgttcg gcccagagta tgcgaaaccg ttcaaaactt
    28321 tttatatggg accaatgttt cgctacgaac gccctcaaaa aggacggtta cgtcaattcc
    28381 atcaaatcgg agtagaagca tttggatcag aaaaccctgc aactgatgtg gagagcatgg
    28441 tgatggcact tgatttcttc aaacagttgg ggatcacgca aatccggcta gtcatcaatt
    28501 cattaggtga taaagaaacg cgtcaagcct atcgtcaagc attgatcgac tatcttttac
    28561 cttttgaatc agagctgagt gaagactcta aacgccgcct tcatgaaaat ccattacgcg
    28621 tattggacag taaagacaaa cgagatcaaa aatttgtggc agaagctcca tctatcttag
    28681 attatctaag cgagcctgct caaaaacatt ttgataccgt tgtttccatg ctggatgcat
    28741 tggctgttcc ttatgaaatc gacagtaata tggttcgcgg actagattat tacacacata
    28801 cgatttttga aatcatgagt gacgcaccaa aaatgggggc acaagcaacg atttgcgcag
    28861 gcggacgtta tgacaatcta gtggaagaac taggtggtcc ttcaacacct ggcttcggat
    28921 ttgcaatggg tatcgagcga ttactcttga ctatggaggc agaggaagta gttatccctg
    28981 catttaatga gttggatgct tacgtggtcg cactcggaga cgaaacaaat atcgaagcat
    29041 tgaaagtggt ccaagcgatt cgaaactttg gtttttcagc tgaccgcgac ttcatgaacc
    29101 gtaaagcaaa agcgcaattt aagacagcag ataaagcgaa tgccaaatta gtattggtga
    29161 tcggtgaaga tgagcttgct agtcaaacga ttaatgtcaa agcaatggca agccgaaaag
    29221 aaaaaagttt tccattagaa gagatatatg aacattttga tgaagtctat gatgaaatga
    29281 ctttattcga gtaggaggaa aaaaataaat ggcacaaaga acgatctatt gcggattagt
    29341 ttccgaacaa caattagaac aaacagttac attaaaagga tgggtacaaa aaagacgaga
    29401 ccttggggga gtaatcttta tcgacctacg tgatcgtgaa ggaatcgttc aaatcgtctt
    29461 taatcctgaa atcaacaaag aagcatggga aatcgcggat aaatgtcgca gtgaatacgt
    29521 gatcgaagtg actggggaag ttagaagacg cggagaaaat gcagtaaatc ctaaaatggc
    29581 cactggtgaa ttcgaagtga ttgcaagtga aatcgtgatt ttgaatcaag caaaaacccc
    29641 gccatttcaa attgaagatg atcaagcaat cagtgacgaa atacgtttga aatatcgtta
    29701 tttggatctg cgtcgtccaa aaatgactaa aaacatcaaa ttaagaaatg cgacaacaaa
    29761 agcgattcgt cattatttag atgataatga ctttctcgat atcgaaacac cttacctagg
    29821 gaaatctaca ccagaaggcg caagagacta cctagttcct tcacgtgtcc atgctggaca
    29881 tttctatgcg ttgccgcaat ctcctcaatt gtttaaacaa ttgctgatga atgctggatt
    29941 cgaccgttat tatcaaatcg ttcgttgttt ccgcgatgaa gatttacgtg gagaccgtca
    30001 gcctgaattt acgcaagtag atattgaaac aacgttctta acagcagaag aaatccaaac
    30061 ttacacagag ggattgattg cgaaggtaat gaaagaagtt cgcggtatcg aagtcacatt
    30121 gccatttcct cgtatgacct atgatgaagc aatggctcgc tacggcagcg acaaaccgga
    30181 tacacgtttt gatatggaat tgatcgatct aagcgataca gtcaaagaag tagaattcaa
    30241 agtcttccaa atggctcttg aaaacggcgg tgtcgtgaaa gcattgaatg ctaaaggcgc
    30301 tgcagatcgc tactcacgaa aagacatgga tcagttaggt caatatgtag gacaattcgg
    30361 agctaagggg cttgcatggc tgaaagtaga agaagacgga ttgaaaggtc caattgctaa
    30421 attcatggga gaagcaacag aagcaatcat taaagcaaca gatgcaaaac caggtgactt
    30481 gctgatgttt ggcgcagata aaagtgaaat cgtcgctgct gcattaggtg ctatccggac
    30541 acgtttagga aaagaattag gactaattga tgaatcgaaa ttcaatttct tatgggtaac
    30601 tgattggcca caatttgaat tttcagaaga agaaggtcga tatgtctctg ctcaccatcc
    30661 attcacgatg ccaaaagaag aagatatccc gttattggct gaagaccctg caaaagtcta
    30721 tgcagaagct tatgatatcg tcttgaacgg ttatgaatta ggcggaggtt ctatccgtat
    30781 tcatactcgt gagcttcaag aaaaagtact agaaactcta ggctttacaa aagaacaaat
    30841 ggaagaacaa tttggtttct tgttaacagc tttagattac ggattccctc cacatggcgg
    30901 tattgcatta ggattggacc gttttgcaat gttattagcc ggagaagata atattcgtga
    30961 agtcattgcc tttcctaaaa acggaaaagc agcagatgtg atgagtgatg caccaagtat
    31021 ggtttcgcct ttacaattgt tcgaattgaa tattgatgta acgaatatag aagaatagcc
    31081 gataaaaagg taaaaaggat ttgtcgaata cgcttctttt gacaaccttg atttaattga
    31141 aaaacacttt ataatgaagc cataacatat aaagcggggc ttttccatga aaaaaacatt
    31201 cgaaaattgg gcttatcatg attacacgac caagctttcg gtatctatcg tttatgcgtt
    31261 gatcgcatca gtcgcattga atttctttta tcagccagga catatttatt caagtggtat
    31321 tactggtcta gctcagattt tgacgacttt gtcaaaatca ctgataggat tcgaagtacc
    31381 ggtatcaaca actttgtatt tactgaatat acctttgttt gtattggcgt ggttaaaaat
    31441 cgggaagaag tttacaattt tcacttttat cacagtcact ttgacctccc tttgtatcca
    31501 tattttaccg gaaacagtcc tatctaccga tccaatcatc tgtgcgttgt ttgggggggc
    31561 tgtgatggga ctaggtattg ggctagcgtt gagaaacggc ctatcatcgg gcggtctaga
    31621 tatcgtgagt atcacgattc gtaaaaaaac aggaaagtcg attggttcta tttcgatcta
    31681 cttcaatgca ttgatcgttt ttgttgccgg aattctattt ggctggcaat atatgtttta
    31741 cagtacgttg tctattttcg tcagtggaaa agtaactgat gtcgtttata ctaaacaaaa
    31801 gaagatgcag gtaatgatcg taacgaaaca tccagaaaaa gtagtaaatg aaatccaaaa
    31861 ctgtatgcgt agagggatca cgatcatcaa tgaagcagaa ggtgcttata agcatgataa
    31921 gcagacagta ttgatgacga tcgttacacg atacgaactg cctctactta gagaagcaat
    31981 gaaagcttct gatccacaag cttttgtaag tattgcagaa aacgtccaga tacttggtcg
    32041 tttctatgag gatggcattt agatcgagtt tgacaaaaat tcatgaaata ctgctgtaga
    32101 cagacgttcg tttgtctgca gtttttttct accatagtag aatcagcaaa gaaaaactgc
    32161 ttttttattt gaaattttct taaagttgaa aaaaagcatg tttatttttt taaatttatg
    32221 ggatgataga aaaaaatagt agagaaagga cacgattcta cttgctattt tcacttaata
    32281 cccgtatatt acgaatgaaa aaagtttatg aaaagttgga atattgaatg gaaaaacaaa
    32341 aaaggttaaa aaacagccgc tacatcactg ggtttgatgg gctccgttca ttagctgtgg
    32401 tgggtgttat cttctatcac cttctgccaa ctagtatgaa aggcggctat ttgggcgttc
    32461 cgattttttt cgtcgtatct ggttatttga tcacggatct gctgcggcag gaatgggaac
    32521 aaaatggaaa aatcaatatt tggcaatttt atgtcagaag aatgaagaga ctctatccgg
    32581 cacttgtttt tatgcttgtg acagcttcgg cttatatcac tttgtttcag cgagggctgt
    32641 taaacaatct tcgaggagtt gtggtcagca gcttactgta tgtcaacaac tggtggcaaa
    32701 tcaataacgg tttatcttat ttcgatcgat ttgctaatga gtcaccgttt acgcatatct
    32761 ggtctttagc agtagaaggt caaaactatt tggtttggcc gatcttgttt gtattgttga
    32821 tggtatttgt tcgtaaaaga aaatggatct tttatactgt gttaggtaca tccttcctct
    32881 ccgccatctt gatgatgatc ttgtatacac caggaggcga tccaacccgt gtttattacg
    32941 gtaccgacac tcgtctgttt tctatatggt tgggaagtgc gcttgcgttt gtttggccaa
    33001 gtacgcgttt aaagaaaaac atcccgaaac aagcgaaaaa tattctgaat atcgctggag
    33061 gaatctcgct tttggcactg attctttgct tcttcttttt agatgatcat tacaatttca
    33121 tctattacgg aggaatgctc ctagtgagtc tgttatgcgt agtgctagtt gcagtgacag
    33181 cacaccccgg agcaagtttg aatcgatggc tgacaaatcc agtatttact tggattggca
    33241 aacgaagcta tggcatttat ctgtatcagt ttccagttat gattttttat gaagcaaagg
    33301 tgactgatat tgccgatcat gttttgttgc atactttagt ggaaatcaca ttgattctaa
    33361 tcatcagtga actttcttat cgatatgtgg agcgtccgct agcacgtttt gattatggtc
    33421 gtacattcca agtgatgaaa ggatggttca gcaaaccgat catcagtaag agcaaaccat
    33481 gggttgttcc aggcacatta cttgtagcaa ttgcactcgt tggtttcgtt acggcaccga
    33541 aaaacgctgt aacagccgat caaaaacaac tgcaggcaaa aatcgctgaa agtaaaaaat
    33601 tagcagaaga aaccagaaac aattcagaaa acaccactag ttcggttgac caagcgatcc
    33661 ttgataagta cgagttgtcc aaggcacaag ggaataaggc acaaaaatta gaactaacgg
    33721 catttggtga ttcagttatg ttggatgctg caacggatct acaagaactt tatccaaaag
    33781 tagtggtaga tggagatgtc ggacgacaat tatatgccag tgtaccgtac attgaaaaat
    33841 taaaggaaca agatttgttg aaagacactg ttctgattgg actaggaacg aatggctcat
    33901 tctcggaagc tcagtttgat agtgtgatgg atgcaatcgg tgatcgaaaa gtatactggg
    33961 tcaatgtccg agtaccgacg aagcgctggc aaaatgacgt gaatgcgatg cttgaacaga
    34021 tgacgaaaaa atacgacaat atgacgctga ttgattggta cagctacagt aatgaccata
    34081 gtgactggtt ttatgatgat caagtccatc caaatcctga agggatgaca cattacattc
    34141 acttagtcag cgaagccttg ctaggaggaa gttcaagtac gaacagcagt gagacaaacg
    34201 tgacagaatg atagctacaa aaaacttcag gcaaaaacat ttgtttttgc ctgaagtttt
    34261 tttatattta ccgtgttttt aacattcata tagattcagg aagcaaaacg gttgagtgtg
    34321 tctgtaaata acgttctttt tgttttcggg tgagtttttt gaatgcagct tctgcttttg
    34381 ttgcttcgct tcttgaagaa aatacttctg catggatcat cttaacaggt cttctttttt
    34441 gaagacgagt atatttagca ccagtaccat tgttatgttc ctctaatcgt ctagaaagat
    34501 cggttgtata tccaccataa aatgtctgat ctttacagaa taatacgtaa aaataatgtt
    34561 catttgccat agagcatctc acgaatctct gcagtgtatt ctccatccat attgtaagtg
    34621 atcaatggtg gagcgacttt gaatccgtct aatttgcctt ctttgattcc ttcaactaac
    34681 aaaatatttg cctcttttcc aggttttggg taaacaaatt ggatcctttt aggtgcaatt
    34741 cgatagtctt ccatgacctg aatgatttct aagaaccgat caggacgatg gaccatagta
    34801 aagcgtccat ttgtttttag tagcttactt gaaatatcga tcacttcttc taacgtcgta
    34861 tgaatctcat gacgggcgat tgccaggtgt ttattagggt tcgttttatt tgttggcagc
    34921 cctttgaaat aaggtggatt acagacgact aagtcacaag aattatgtcg aacgacagat
    34981 aagctgtctt tcagatcgat ggtgtggaca gtcatttgtt catttaaatg gttaagcgcg
    35041 atactacgtc ttgccatgtc tgctagacga ggttgaagtt cgatagcgtc gatagccgcc
    35101 tgggttcgtt tacttaaaaa aagtccaact gcgccatttc ctgcacaaag gtcaacaatc
    35161 ttcccttttt taggtacacg ggaaaagtga gcaagcagca cagcatctaa agaaaaagaa
    35221 aacactttgg aactttggat aatcttgata tcttctgcgt ataattggtc gattcgttcg
    35281 tcttcgtgaa gcatggattc cctccaaaat gaaaaaaata gtcgtctgta ttatactatt
    35341 tttattaaaa agaaccaagg tggcttgtca aacctctatt ttttatgcat actatgacca
    35401 taagaaggga aaggaagaga ctatgtttta tcgatttatg cgcggggtag ttcgagtact
    35461 attagcctta gttaatggaa atgcccgcta tgagaataaa gaagttttac cgcaagatga
    35521 gaattacata ctagttgctc cccatcgtac ttggtgggac ccattatatc tggcggtagc
    35581 tgcagcaccc aaggaattca gctttatggc aaaagaagaa ctgttcaaaa atccagttct
    35641 gcgatttata ttaactcgat ccaatgcttt tccagttaaa agagaaaatc caggaccaag
    35701 cgtcattaaa acacctgtaa agattttgaa atcgacaaat ttgagtttga tcatgtttcc
    35761 cagtgggaca agacatgcta cagaacttaa aggcggaatg gcattgattt ccagaatgtc
    35821 taaagcgaaa atcgtgccag ctgtatatca aggtccgttg acacttgggg atctgttcaa
    35881 gcgtcagaga gtgacagtgc gtttcggcga accaatcgac ttatcagata tcaagaaaac
    35941 ggataaagaa ggtatggcgg agatcgaacg acgaacacaa gcagcttttg acaaattgga
    36001 caaagaagtg aaccctgatt tcaaatatga agtcaaaaaa aaataaaatg ataagtttat
    36061 gcgtgggcgg tcttttgaat ctactgtcct gttcagttca gactttttca atgaaaacga
    36121 gggagagacg tcaagtctgc cctctttttg cgttccaata tgtaaaatag aagacaggtg
    36181 tcatgtaatg gatcaaagtg ttataataat tagaaggaca ttttttgagg tgattgaatg
    36241 cgttttttac atacagccga ttggcatatc ggaaaaaaac tacaaggtta tgacttgatt
    36301 gaagaccagc gtcatgtact atcttctata ctagatatcg cgaaagaaga aaaagtagag
    36361 gcaatcgtga ttgccggaga cttatatgat aggagtgtcc cagctgttga tgccgtagaa
    36421 ttatacaatg aattgatggt cgattggaat ttaaaggaaa agatcccgat ttttgctata
    36481 tcaggaaatc acgatagcag tacgagactt tcagcgggta cgccatggtt cagttattcg
    36541 aactattttt tgcgaacaca gctagcagaa gcatttgaac cagtcgagtt taaaaacgta
    36601 caatttttct ttcttcctta ctttgaacca attgcagcga gattatattt tgaagatgac
    36661 aatatccgaa cgatcaagca agcggtagcc aaggtgatag ataaaatgca ggagctattt
    36721 gattcagaaa aaaaacaagt attgattagc catttttttg taatgggaag tgtaaaatct
    36781 gattcggaaa cgaaaatcga agtaggcggg ttggattcga tccctggtga actacttaca
    36841 ccgtttgatt atgtagcact aggacatttg cataatcaag ctgctttgag acaggataat
    36901 gctcgctata gcggttcccc attgaaattc tctttatctg agatcaacca aaaaaaaggc
    36961 gtatggatcg ttgacctgac aacaggcctg gagttgaatt ttagggagat cgaacccctg
    37021 catgatattg aagaaataac agcgagtttc aaagaattgc tggatcctgc cttttatcag
    37081 tccgtcaatc gggagaatta catctatatc tatctcactg atagaacgat catcccgaat
    37141 atgatgaacc agcttcggca aatatatcct cgtattttgg ggattgaacg ggcaaacggt
    37201 cgagcagaac aaacaaagcg caaacgaaaa gtactagaaa tgaaagatcc tcaaaaatta
    37261 gcagaagcat tttttagtga aatgacggaa gagcagctaa ctgcaaacca agaaaaatgg
    37321 ctcggagaaa cgttgcaaga aatcatggaa atggaatgat caagaatgaa accgaaaaaa
    37381 ttacaactta aaaattttgg tccttttatc aatgagaccg tagatttttc acgtttgaca
    37441 gaagcaccgc tttttttgat cagcgggaag acaggagctg gcaaaacgac gatttttgat
    37501 gggatcacct tcgcactttt tggtgaaact tccggaagac ttcgctctgg aaaagagatg
    37561 cgttctttgt ttgctacacc agacgaagaa acaagcgtga ctttttcttt tgaacatcag
    37621 cagatgagct atgaaatcga acgaaaacca gaacaagttt tagcaaaacg aaaaggaaac
    37681 ggaacaaaaa aacaggcagc caaagtaacg ttgaccattt ttgatgggaa aggaaaagaa
    37741 ataaaacaaa tcacaaaacg tacagaagca gatcagttga tcagagaact gatgaatctc
    37801 gatgcgaaac agttttctca aatcgtttta ctaccccaag gagaattccg taattttttg
    37861 gtttcatcaa gcagtgataa agagactgtt ttacgtcatt tattcggtac tcaatttttc
    37921 caacagttca atgagcgatt aaaagaaaaa gcaaaacaac agcaacaaaa attggatcat
    37981 ttagagcaag agctgcatct tctgcaaaaa aggtttgttt tagtcaaaga agaggaacca
    38041 gcagcagggt ttgaagccgt tttagcccaa tggacaaacc atcaggcaat actcgaaaaa
    38101 caaatcacgg aagaaaaaga agctctaacg gaacttcagg aaaaacaaaa gcaactagaa
    38161 aattcctact atcgttttga aagcttgaaa aaaagttatg aagaaaaaac gatattaata
    38221 aacaagcaaa aggaattagc tgctcaaaaa gacgaaatag aggaaaagaa acgatggatt
    38281 gggtattatg aatttacgca acgattagtc gaaccaatcc agcgcctaca agaaataaaa
    38341 gttgaaaaaa tagaactgtc acaaaaaagt agtgagcaaa caaagaaact agcgatgact
    38401 acgcagaatt atgaagagtg gcaaaaaaat gaagcaaacc gcgtacgccg acaaacaaaa
    38461 atcaaagaag ctgctcaaaa actgcaaaac aaacagatga tggtgccaat tgtcgaatcc
    38521 ttacgtagta aaaaacaaga cgcagaacaa ttaacaattt cattggataa agaagaattg
    38581 aatgccgaga agctgtatca aaatctcgct atctatcagg aaagaactcg aattcttcaa
    38641 gaaaatttac tggatcagga aaaactgcaa gaagatcgtc ttgcttttgg acagttaaaa
    38701 tatctagatg aaaagcagca agaaatagaa aaacaaaaag caaaagacac tgggtcgctc
    38761 gcacagataa gagaagaact caaaaaagca actgaagaaa taacaaaaaa tagtcagcta
    38821 ttgaaagaac agacagaaca agcagaacag ctgaaaagcc aatgggcaaa gcagcaaatt
    38881 gctcgtcttc agcttttttt gcgtccaggg gagccatgtc ttgtttgtgg atcaacggaa
    38941 caccccatac aacaattaaa acacgaacag ccaaataagg aagatatctt aaaagtagaa
    39001 caacaactgg cagaagctga gtctgctgta gaaagaactc agcaaatcat tgccaaaagt
    39061 gaagcacatg aaaataatct tcaacaacaa ttatcagatt tagaacaaaa aatcatggca
    39121 acgaatatac aattggctga acaagaagaa cacttgcaac aggctttgaa aaaggcattt
    39181 cctgagataa cagaacaaaa aacaaaaaca actcttgtag taatcgaaca atctttagat
    39241 agacgaaaaa gcaagatggc caatgcaaga atagagctgg aagaaataag acaacaagca
    39301 gaaaagctcg aacaacaatt agctgtctac aaacagcagc agacagaaaa aaataatcag
    39361 ctccagcaac tgcaaggaga aatcaaaagt ttagaacaac aattgcaaga tacggatagt
    39421 aactgtttag aagaggagat acgacgactt gaaaaacagt tagaagaaga ctcgaatcaa
    39481 ctagctgttg agcagaaagc aggagtgcaa ttgttgcaag atcttcatac gcttcggaca
    39541 cagcttgatc ttcaacatga acaaatagaa aaaatagatg aaaaaataga aaaggaacaa
    39601 gaaagaatag ctaaaaagtt agaaagccag tcgtattttt caacaattga agaaatctgt
    39661 gcatttgcac aacagcaagc acaatataaa gaaaaccaac gtacagttac ttcttatcat
    39721 gaagagcaat tagtgacagc tgaccggctg cgtcaattag aaaatatcca gctaactgag
    39781 acattcccag atacagaaga gatcagccaa cagttagaag aaataagacg tatgatcgaa
    39841 ataaagcaag aaaagatata cggtttacaa gaacaaaaaa ttagtaatca aaaaatctac
    39901 gatgaatgtc tttcgattta tcacacaagc cagacgaaat tagatgagct tacgcaatta
    39961 cagcagcttt cgcaaacatt caacggagaa aatcctaaga agactagttt ggaacggtat
    40021 gtgcttcagg tttatcttca agaagtgtta caagtagcaa atgatcatct ccaacgttta
    40081 acgaaaaatc gttatcaatt tgagctagcg gataccattg gcagttatcg agggaaaacc
    40141 ggattagaaa tcaatatcta tgatgatcag gcaggtatgt ctcgaagtgc gcataccctg
    40201 tctggcggtg agagttttat tgcagcactt tctttagcat tagctcttgc cgatgtgatc
    40261 cagacacaag ctggtggtgt agcaatcgat gcattgttta ttgatgaagg atttgggtca
    40321 ttagatgaag aagctttgga aatggcaatg gaagctttag aaacgatcga aagtgaagga
    40381 agaatgatcg gcatcattag tcatgtaaga gaattgaaag aacgagtatt acaacaaata
    40441 agaattgata cagaaggtag cggacaaagc aaaatacgct atcaacttgg ataaaaaggg
    40501 agattggtaa ctatgaaatg gagtattcca gaaaaagtca ttgcacgtgg acgtcaatac
    40561 ttgcaagaag gccgagtgtt atcggttgtc cctgaccaag aagaaaacgt gtggcatgca
    40621 gaagtcttgg gcagtgaatt gtatatggtt gatttggatg gtacagcaaa agagatagat
    40681 tactgccaat gtccctattg ggaggaacat aaatattgta agcatacagt tgctgtggaa
    40741 ctttatttac ggtcgaaaaa tctatctcgt atcatgaaaa aagaccagcc aatgctagaa
    40801 ccggtaaaag caacaagtga gggagaaatc attgcaaaag gtttttctcg tctaaaaaca
    40861 caaaacaatc ctcaagcggt gcaacctttg attattgaat accaagtaga aacgattgag
    40921 actaatcagt atcacccaga gctttctatt ttggcacttt acttgcgtat cggttcattg
    40981 gcatcaccga aaaaaacata tatcgtaaaa aacatctatg attttttaca agcttacaca
    41041 gaaaaagaaa cttacactgt taataaacag taccagtttc gtctagataa acgggcgttt
    41101 caaaaagaag atcaaaaaat actcacgcat cttgcaggaa gtgctcagac gcatcaatta
    41161 ttaggtacga acggcttaca agtcaaagga aaactagata aaagatatct gcttctccca
    41221 gtagaacaag cccgcttcct gttagagcag atgaatcaga ctacacgttt gcatctgcag
    41281 ataaatgaac aaaacgatca aggaatacaa ttttccgatc aaaacaaacc tttatcattc
    41341 aaagtggaaa aatttggaga agattatttg ctgcaagcat tgaatgattt tgattttttc
    41401 tttatgcatt atcagtgggg agttatccaa gggacatttt attctctgac gaaatatcaa
    41461 caaacggttt atcaaacttg gaaacaattg attcgccgat tggagaaacc agaagtagtg
    41521 ttcaagaaaa aagaattacc gtctttgttt aaagagatta tccctctgct gtcagagatc
    41581 ggcgacgtag ctattgcccc tgcagtagaa gaggaagtag cagatatccc cgtcgaattt
    41641 attttctttt tccgaaaagc aaaaggaaaa atccaagctc gagtcgattt cgtctatggt
    41701 gaagtcatct attcgactga cccgaagcat gaggtctcga cagaacaggc ttttcaggtg
    41761 ttacgtgaca cagtagaaga gaaacgagta cttgatctat tcagaatgta tcgctaccag
    41821 aaaaatgaaa ctggttatga acgtccattg ccaagcgggg aagaactata tgcctttttc
    41881 cgcacagaac tatctgtctt ccgtcagttt ggtgaagtca gacttggaag aaaattgcga
    41941 gagttgtatt tagatgcgca taaacatcaa ccgaaaatcg aagtaaccga gaccggttca
    42001 tggctcgata ttcgattcga tgtgacaggg atagaggagc aagaaatcga tcatgtcctg
    42061 caaagcttgc tgagaaatga tgctttttat acattagaaa atggtcaggt tctttctttt
    42121 gattcagaag aatttcaaca aacaagccaa gtgttgcaac aattacggga atcgatacgt
    42181 acagaagaag gaacgatcca tgtacctaaa aatcaaggat tgatcattca aaatcaattg
    42241 gaaaaaagca atgctacttt tagtgaatcg ttccaaacga tggtacaaga tctcattcat
    42301 ccagaaagat accaggcaca gcttcccaaa ggattgaatg caacgatgag agattatcaa
    42361 aagcaaggtt ttcgatggtt gaagatgtta ggtcattatc agtttggcgg tattttagcc
    42421 gatgaaatgg gacttgggaa aacactacag acaattgcct ttttactttc ggaaaaagaa
    42481 gaacggaaaa gcttctctgc tttgatcgta gcgcctgcga gcttaattta caactggcag
    42541 gcagaggtga gaaaattcgc cccttcttta agtatccaag taatcaatgg gaataaaaaa
    42601 gaacgtgaag aattactggc taaagacaca gatatccgag tgacttctta tgccagctta
    42661 agacaggatc tagctaatta tcagtcgcaa aaaattgatt atttgattct tgatgaggca
    42721 caaatggtca aaaatagcag tacgaaaact gcacaagcat tgagagaatt agctgtacct
    42781 cagcggtttg cactgagtgg gacaccaatc gagaataatt tagaagaatt gtggtcattg
    42841 tttgcaacga ttatgccagg atttttcccg actaaaacaa aattcaggga acttgccgca
    42901 gaagaaattg cgcaaatgat tcgaccgttt attttacggc gagataaaca aactgtgttg
    42961 aaagacttgc cggaaaaaac agagatgaat ctatattctg cacttacaga agaacaaaaa
    43021 actgtttatt tagcttactt gcgtcaaatg cgtgaagaaa tcacatcaat ggattctgaa
    43081 gcattcaaga aaaaccggat cgggatactt gctggtctga caagactgcg acaaatttgc
    43141 tgcgatcctc gtctgtttat tgaagattac caaggcggtt ccggcaagct cgaacaagta
    43201 aaagatctac tggtagctgc caaagagaac aaacgaagag ttttgctgtt ttctcaattt
    43261 acagggatgc tgactatctt gcaagaagag ttagccgagc tagggatctc gacattttat
    43321 ttaagaggca gtacgaaacc acaagatcgg ttaagtatgg tagacgcatt taatgctggc
    43381 gaaaaagatg tttttctgat ttccttaaag gctgggggaa ctggattgaa tctcacggga
    43441 gcagatacgg tcatcttgta tgacctttgg tggaatcctg ccattgaaga acaagctgct
    43501 ggacgtgcac atcggatcgg acaaaaaaat gtggtagaag tgtggcgtat gatctctgaa
    43561 ggaacgattg aggaacgcat ggattcactc cagcaagaaa aacgcgaact gttccaaaaa
    43621 gtgatccaag gtaatgaaga acagttgacg aaactgactg aagaagacat ccgcatgatt
    43681 ttaagtgtag gagaaatcga ggagtaagag actcgaaaaa gcgttcagta atgggtaaga
    43741 aagcctttct aaagaagcga ttgtttattt gatttaaaaa atagcaagga ggctgggatt
    43801 ccattttatc ccagcttcct tgctatcatt tttttatttc tatttttaaa ggttatacaa
    43861 agattgtctt cattgtctct aacagctgat caaaagaaga aatctcgata tcgcaaattg
    43921 gagtctgttc aattttgcgt tctcgatggt tgaaccaaag cgcttgccag ttagcacttt
    43981 ttgcacctag aacatcattg tcgtaattat cgccaacgta taaggtctct tctggaagca
    44041 tatgaaattc tttctcagcc agctgaaaaa tctctttttc tggtttttgg aaacctgttg
    44101 cttgagaaat gagcatattg cgggaaggaa tccaattgtt caattgaagt tgcttcagtt
    44161 tttttgtctg atggtcagtc ggcccatttg tgataattcc taatgggaca ttcttttcct
    44221 tcaagaaatc gagggttttt ttgacctcct catgcaagca gatattatca agttcttcct
    44281 cgtaaatttt ttgaaataag aggccatctt cttccgtaat atgagggtag tctaaatctt
    44341 ttagtgattg gctgatccga tgtgctcgca tatattctag tgtccaatct cctgccatta
    44401 cttttgggaa gttttcatca ctatgatggc ggaaccggat atatagtgga tgcatatctg
    44461 catctgaaac aagcggaacg actcttttga ccgcgtttcg aaatggctgc tgctgatcat
    44521 acatcgtatc atcaacatca aacacaactg atttaatcaa aattttacac gcctttcggt
    44581 tttcattgat tttttcacaa atccttgact attgtaacag aaaaaattgt ctaaaaaagc
    44641 tgataaataa aggtttttct tactatattt ctatttcctt gacagaataa ggtttttata
    44701 tttcagtttt tttcactaaa aatcgtgaaa cacgtcaata agtttgatga acaaattaat
    44761 cattatggta gaagtcgatt gatttatttt aatgcaatct ctgtggaatt ttcgaaagat
    44821 ttattttttt aatacagtct caatataact attcaaacat aaaataacgt tatttgattt
    44881 atttgtttat agtaaatttt atttagtaat cattgcttta aaatactacg cttatataac
    44941 agagaaaata agcgttataa taaagaacag tattatttaa aatgacagaa aacattacta
    45001 ttaaagaaat aaaaaacata aaaaatctta agaaatcggt ttcatttagc ttttgagata
    45061 aaataatagt acagttttat acgctgtttc atatgtttag aaaatttgaa ttagatttga
    45121 aaactctaat ttttaaatga taaaaaa
//
LOCUS       DAZUJR010000012        40034 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.012, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000012 DAZUJR010000000
VERSION     DAZUJR010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 40034)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40034)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40034
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.012"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(51..632)
                     /locus_tag="ACG804_000631"
     CDS             complement(51..632)
                     /locus_tag="ACG804_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ReoY family proteolytic degradation factor"
                     /protein_id="HFS4831583.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(638..1897)
                     /locus_tag="ACG804_000632"
     CDS             complement(638..1897)
                     /locus_tag="ACG804_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFS4831584.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(1899..2945)
                     /locus_tag="ACG804_000633"
     CDS             complement(1899..2945)
                     /locus_tag="ACG804_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831585.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(3180..3455)
                     /locus_tag="ACG804_000634"
     CDS             complement(3180..3455)
                     /locus_tag="ACG804_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HFS4831586.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(3698..5008)
                     /gene="der"
                     /locus_tag="ACG804_000635"
     CDS             complement(3698..5008)
                     /gene="der"
                     /locus_tag="ACG804_000635"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HFS4831587.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(5190..6419)
                     /gene="rpsA"
                     /locus_tag="ACG804_000636"
     CDS             complement(5190..6419)
                     /gene="rpsA"
                     /locus_tag="ACG804_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HFS4831588.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(6554..7234)
                     /gene="cmk"
                     /locus_tag="ACG804_000637"
     CDS             complement(6554..7234)
                     /gene="cmk"
                     /locus_tag="ACG804_000637"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HFS4831589.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(7283..7918)
                     /locus_tag="ACG804_000638"
     CDS             complement(7283..7918)
                     /locus_tag="ACG804_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HFS4831590.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(7984..9387)
                     /locus_tag="ACG804_000639"
     CDS             complement(7984..9387)
                     /locus_tag="ACG804_000639"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0043138 - 3'-5' DNA helicase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HFS4831591.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWGTILLNLFKKNMEH"
     gene            complement(9374..10405)
                     /locus_tag="ACG804_000640"
     CDS             complement(9374..10405)
                     /locus_tag="ACG804_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4831592.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            10436..10657
                     /locus_tag="ACG804_000641"
     CDS             10436..10657
                     /locus_tag="ACG804_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HFS4831593.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(10822..11559)
                     /locus_tag="ACG804_000642"
     CDS             complement(10822..11559)
                     /locus_tag="ACG804_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HFS4831594.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(11712..13052)
                     /locus_tag="ACG804_000643"
     CDS             complement(11712..13052)
                     /locus_tag="ACG804_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFS4831595.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(13289..14812)
                     /locus_tag="ACG804_000644"
     CDS             complement(13289..14812)
                     /locus_tag="ACG804_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HFS4831596.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(15190..15801)
                     /locus_tag="ACG804_000645"
     CDS             complement(15190..15801)
                     /locus_tag="ACG804_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFS4831597.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(15924..16049)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(16131..16847)
                     /locus_tag="ACG804_000646"
     CDS             complement(16131..16847)
                     /locus_tag="ACG804_000646"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFS4831598.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(16853..17422)
                     /gene="scpB"
                     /locus_tag="ACG804_000647"
     CDS             complement(16853..17422)
                     /gene="scpB"
                     /locus_tag="ACG804_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HFS4831599.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(17406..18176)
                     /locus_tag="ACG804_000648"
     CDS             complement(17406..18176)
                     /locus_tag="ACG804_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HFS4831600.1"
                     /translation="MNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDIPIATITEQY
                     MNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEEDPREELVTQ
                     LLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKKIDLIRAMQK
                     ILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESPSKSEVVTTF
                     MALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(18173..18544)
                     /locus_tag="ACG804_000649"
     CDS             complement(18173..18544)
                     /locus_tag="ACG804_000649"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4831601.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(18563..19450)
                     /gene="xerD"
                     /locus_tag="ACG804_000650"
     CDS             complement(18563..19450)
                     /gene="xerD"
                     /locus_tag="ACG804_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HFS4831602.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(19546..20019)
                     /locus_tag="ACG804_000651"
     CDS             complement(19546..20019)
                     /locus_tag="ACG804_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFS4831603.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(20124..20987)
                     /locus_tag="ACG804_000652"
     CDS             complement(20124..20987)
                     /locus_tag="ACG804_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor B family protein"
                     /protein_id="HFS4831604.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(21183..23282)
                     /locus_tag="ACG804_000653"
     CDS             complement(21183..23282)
                     /locus_tag="ACG804_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division site-positioning protein MapZ
                     family protein"
                     /protein_id="HFS4831605.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            complement(23502..24611)
                     /gene="rpoD"
                     /locus_tag="ACG804_000654"
     CDS             complement(23502..24611)
                     /gene="rpoD"
                     /locus_tag="ACG804_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HFS4831606.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(24635..26476)
                     /gene="dnaG"
                     /locus_tag="ACG804_000655"
     CDS             complement(24635..26476)
                     /gene="dnaG"
                     /locus_tag="ACG804_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HFS4831607.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(26658..28973)
                     /locus_tag="ACG804_000656"
     CDS             complement(26658..28973)
                     /locus_tag="ACG804_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFS4831608.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(29158..30018)
                     /locus_tag="ACG804_000657"
     CDS             complement(29158..30018)
                     /locus_tag="ACG804_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HFS4831609.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(30077..30709)
                     /locus_tag="ACG804_000658"
                     /pseudo
     CDS             complement(30077..30709)
                     /locus_tag="ACG804_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289460.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
     gene            30876..31637
                     /locus_tag="ACG804_000659"
     CDS             30876..31637
                     /locus_tag="ACG804_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFS4831610.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            31663..34254
                     /gene="mprF"
                     /locus_tag="ACG804_000660"
     CDS             31663..34254
                     /gene="mprF"
                     /locus_tag="ACG804_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HFS4831611.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(34442..35629)
                     /gene="tuf"
                     /locus_tag="ACG804_000661"
     CDS             complement(34442..35629)
                     /gene="tuf"
                     /locus_tag="ACG804_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HFS4831612.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            35997..36353
                     /locus_tag="ACG804_000662"
     CDS             35997..36353
                     /locus_tag="ACG804_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFS4831613.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            complement(36594..37598)
                     /locus_tag="ACG804_000663"
     CDS             complement(36594..37598)
                     /locus_tag="ACG804_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HFS4831614.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            37764..38615
                     /locus_tag="ACG804_000664"
     CDS             37764..38615
                     /locus_tag="ACG804_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFS4831615.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            38632..38877
                     /locus_tag="ACG804_000665"
     CDS             38632..38877
                     /locus_tag="ACG804_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831616.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            39064..39768
                     /locus_tag="ACG804_000666"
     CDS             39064..39768
                     /locus_tag="ACG804_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831617.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
BASE COUNT        11302 a         8403 c         6864 g        13465 t
ORIGIN      
        1 attccacatc cagctgacct ttgtcttttt tagtactata ctatttttaa ctaattgtta
       61 tgttcactta cccggttact tttcttttgt gtctgcaaaa ggatctttcg gttaacttca
      121 tcagataatt tcaaaaaagc atccctatct ccatcttcta gtgcttgatc gatttgagca
      181 taaagcattt ttagttttgc ctcttcttct ttttcttgaa aatatcgttc aattaattca
      241 gtatcttctt cactgactga agaatcccaa gaagaaaatg gattgtcttc taagatagat
      301 agatattctc ttgtctgcca agcattttcg aatatacatt ccacatataa aggctttttc
      361 caattcaaac ggatttcatg aaaaatctgg tctgtgtccg taaattcttt tccctgcaaa
      421 aacaatttca tgggttcccc ttcaacagat agatcactga tctgcagtcc tcgatccgca
      481 aaattcgccc cttcaacaaa gtggacattg cttaaaatcg cttcatgatt ggcaagataa
      541 ttcaagatcc aaaaaacttc tcttcggcta aaagatacat gattgaccat ccacgttaaa
      601 aaattcttct tttcccgtac atcaattagc atttttctca cctctctgtt aggtcatcta
      661 ataatgacag tgcctccata tctcctggtt caagtgttaa ataataagtc aataattctt
      721 gcgctctttt cagctgccct tcttctctta agaaaaaggc atactctttc aagaaatctg
      781 gttcatgtga tagttcatga taagcctgtt catagtgtac agctgcaacg gtaaagtctt
      841 ctaattcatt ataagcatgg gctaggttcc attctgcata aggattagca gtttcttcca
      901 tctgattgat cacttgtatc acatcttcat atctttcatc atccaagtaa agattactta
      961 aagtaagtaa tgtttcatct tgtttgtctc ctacttctaa agctttcagt aaaagttctt
     1021 ctgctcgctg tctatcatgc agacggaaag cattttccga ggccaggtga taaagttcga
     1081 cttggtaagg attttctttg attccttctt ctaacactgt ttgtgcttct tcaatcattt
     1141 cttcttcttg aagagcttgt cctagatata gatataacga ttgataatgc ggattaactt
     1201 ctcgaagttc ttccagatag ttgattgcct gctgattttc tttcaattga agattcgtaa
     1261 aagctagctg gaacagtcga tcatctgtcc tttcttcttt cagtgcttct tctaaaggta
     1321 cgatagctgc ttcgaattct ccttgcatac ttaaggattg tcctaaacgt tcctgcatcg
     1381 agattcctga aatttcattt atcccgcttg ccaacaatgt ttcataaacc actgctgcct
     1441 ctttgaaacg atcaactgaa aaatacaatt cagctagcgc aaactggatc aatggttcat
     1501 caggaagcaa cccagctgct tctttcaatt ttgcttcact cacttcaggg attccgataa
     1561 cttggtacaa atcagctatc gccaataagc tttgcggata gtaatcactt tgcttatcca
     1621 ctttttccag gtattcaaaa gctaagtcga tctcattatc ttcgattgca atttctgcta
     1681 acgggatgtt cagtccgtca ttttctgggt attggttgat cagttgttca aaaatctgtt
     1741 ttgcttcgat caaaaagcca atagccagca attcttcgcc tagttcagct aatatatctg
     1801 ctgggtcttc ttttaatgct ttttctaaaa agatttgtgc ttgtgacaag tcttcatctg
     1861 ataaagcttg caacattttt tcgctatttg tattcatttc aattccctct tatctcactg
     1921 acgatttgtt gaaataccgt cattgttctc aataattctt tttcgtttgg atgttggtat
     1981 ccgtctatta tacctatttt ttctaaaaca agtatttttt tgcttttttc tgccaaaaaa
     2041 agaacttttt ccaaatactc catctttgaa atctgttcca gccagtggat tggatagcca
     2101 agcaagtcca gccacacaaa aaagtttttt agttggaaat caaaaggata tgcttggaga
     2161 ttccacacga aatgaaacat cattcctaaa aattttttca tactagcaga aagtagatgg
     2221 ccattttcgg tcagataaaa agcttgttca aacagtttac cataatttga caggttttct
     2281 gcctctaatt gataaaaata gatcatttct tcgatcatcc cggcaaacgg ccgagtcgtt
     2341 aattgctttt tatttggata gtttttatac agattttgca aaaaacgatg atcacaaatc
     2401 attccgcaac agataaaagt caaaaagtca atctgctttc cgtccacctg ccgctcgctg
     2461 attgtttgat cataaacgat gcgttctggc agattgatgg tttgcagcac tacacgattt
     2521 ggtagctgca aaatcgtccg ctgcggtgtt aatgctcggc ttagagaacg gatcgataca
     2581 gggatcatcc atagtgatga atcaagggtt gtatgttttt gaaaaaaacc tgccagatcc
     2641 atgatccctt catttccaaa tccgatgata aacatggatt gattttcggg atagcgtttg
     2701 acgaaatcaa gcaggttctt taattctgtt aaatgattgc attgagtgtt ggcacaaata
     2761 taccagtcat tgtttgcttg atttgcaaat aacgggttga tcttatctgc aaacaaatca
     2821 taatagcgct gattcgttaa aaataagatt ggctgatcaa tggaaagttc tcttagctga
     2881 ctgactagcg tttctccgta aaacactttc gtcaacgcat cttctacttg ataatcaagt
     2941 tccatacgca tccctcctct tcttattttt attttaccat tagtaagcaa attctagaaa
     3001 agataagagc aaagctcacc tcataacttg caaataaata aaaattaaat aaaatacatg
     3061 tgttttctat gtatgacata cggattcgga atctctgtct cttatttatt ccttttctgc
     3121 taggaaataa aaagaaaagc acttgtagcc ctagagccac aagcgctttt tcaactgtct
     3181 tatttaacag cgtcttttaa tgctttacct ggtttgaatg caggtacttt gctagctgga
     3241 atttcgattt cttcaccagt ttgtgggtta cgacctttgc gagctgcgcg ttcgcgaact
     3301 tcaaagttac caaaaccgat taattgaact ttttcgccgt tagctaaagc atcttgaata
     3361 gttgaaaata cagcatctac tgctgcagtt gcatcttttt tagttaaatc agtagctgaa
     3421 gcaacttttt cgattaattc tgctttgttt gccatggata gattcacctc ctccacaaga
     3481 gatatgatag aaatatcatt tagttaaaac tttctgagtg gtccagaagt ttaaaaagaa
     3541 atattgatta acttcaatat tctgttatca cgatatcata tgaaccgctt aatagcaagg
     3601 tttttaccaa ttttcacatg ctttttttag tcatagaaac gtaacaaacg aaactgtctt
     3661 tttcttttga aaaaaaaacg tcgatatggt aaaatgccta ttttctccta cgagggataa
     3721 ttcggatgga cgtcccttca aaagtaaatg cttttctgat ttgattttct aagaaacgtt
     3781 cataagaaaa atgcatcaat tcctcttcat tgacaaaaac gacaaatgta ggtggtttga
     3841 cagcgacttg tgtagcataa aaaatcttca ggcgttttcc tttatctgtt ggtgttggat
     3901 tgattgctac agcatccata atgatatcat tcaacacagc cgaagagata cgaagattct
     3961 ggttcatact tacttgttcg atcatttcag gcagacgttc caaccgttgt ttagtcactg
     4021 cagaaacaaa aacgattgga gcgtaatcaa gataccggaa ttcatcacga atctcttgtt
     4081 cgaaatcacg cattgtattg gtttctttct ttacaagatc ccatttattc acgacgataa
     4141 taattccacg accagcttca tgggcgtaac ccgctactcg cttgtcttgt tcccgaatcc
     4201 cttcttcagc attcagtacc atcaaaacga tatcagaacg gtcaatggca cgcattgcac
     4261 gcatcacgct gtatttttca gtattttcgt atacttttcc gcgtttacgc ataccagctg
     4321 tatctatcat taagaatttc tgaccacttt cagaaacgaa gtgggtgtcg attgcgtctc
     4381 gggtcgttcc ttcaatatcc gaaacaatta cacgttcttc tcctaaaatc gcattgatca
     4441 aagaggattt accaacattt gggcgaccaa tcaaactaaa cttaatcgtg tcgtcgtcct
     4501 cttcttcagt ctcttcagag aaatacttca ctgcttcatc taaaatatca ccaatcccta
     4561 gtccatggct tcctgaaaca ggataaggat cgcctagccc taaggaataa aattcataga
     4621 tatcgtttct catttctgga ttatctactt tattgactgc taaaatcact ggtttattac
     4681 ttctgtataa aattttcgca accatctcat ctgcgtctgt cacgccttcg cgtccgctga
     4741 ctacacaaat gattacatct gcttcttcaa tcgcgatttc tgcttgatgc ttgatctgat
     4801 ccataaaagg ttcatcgcca agatcaattc cgcctgtgtc gatcacgctg aattctcgac
     4861 ctaaccattc accttttgca taaatacgat cacgagttac tccaggagta tcttcgacaa
     4921 tcgagatacg ctcaccagcg atgcggttaa aaatcgtaga cttaccgacg ttcgggcggc
     4981 caacgattgc aattgttgga tttgccatat tatttcctcc tcacaagttt ccaatctcac
     5041 ttagtttaac gaatgcattg ccaactttca agcatagatt gtcaattaaa cgaagtattt
     5101 ttattcctta ttgaaatact aatcgctttt caaaagaaaa actgagacaa aagcagctgc
     5161 tttcatctca gtcacagata caaaatcaat tatttttcag aatcatcggt tgctttttct
     5221 tctacttctt ctttcaacgc atcacctaaa atgtctccca tagtaaatcc agtattttct
     5281 tctggtaatt cataagactc aacatttttt ggttcttctt ctgaagctgg tttttcttct
     5341 aaagctttga tactcaatgc aatacgatgt tcttctggat ggatctctaa tactttcact
     5401 ttcacttcgt caccttcatg aagcacttca tgtggtgtcg caatatgttt atgtgaaatt
     5461 tgagagatat ggactagccc ttctactcca gggaacactt caacaaaggc accgaagctt
     5521 gtcaaacgtt taactgttcc gtctaatact gtgccaactg gagcttttgt atcgatttct
     5581 gaccaaggtc caggctgtgt gtctttgatt gacaaggaaa cacgttcttg ttcaggattg
     5641 atagacaaca ctttgacatt tacatcatca ttgacagcca atacatcact tggttttgct
     5701 acatgactat gtgaaatctc tgagacatgg actagaccgt caattccgcc taggtcgaca
     5761 aatgcgccaa aatcagtaag acgtgcaaca cgtccactga gaacatctcc ctcatggata
     5821 gttgaaagaa tttctttttt cttttcttct ctttcgtttt ccactaccgc tttatgcgat
     5881 aagatcaaac gattttctga tggttcgatt tcgatgattt taaagctcaa tgttttgcct
     5941 ttatagtctg aaaagtctgc aacaaaatga tcttccacca ttgatgcagg gacaaaacca
     6001 cgtacaccga cgtcaacgac taaaccgcct ttgacaacat ttgtaacagg tgcttcgatg
     6061 accttgccct cttggaaatc tctttcgata tcttcccaaa cttttttagc atctaaacgg
     6121 cgttttgaaa gtagatagct gccgttttct ttatctttgc cgatcgtact gataacgact
     6181 aaatctaata catcaccgac ttttactact tcgctgatat cttctaccgg caaagttgat
     6241 aattcttttg ccggaacgac tccttcaact ccagcccctt cgattccgac aatcacttgt
     6301 ttgtcttcaa tgactaaaac ttcgccctta acaacatcgc caacttttac ttcttgtacg
     6361 cttttcattg cgtcttccat tgactggttg ttctcttgat tttgatcaaa ttctgtcata
     6421 acacttgtcc tcctaaccaa cattctgccg taagtacggt actgttttta gtttaattga
     6481 ttattcaaaa aaaataaagc gatttcgttc gttttccttg aaaaaacaat tgtttttcat
     6541 tttttttctt aatttaaaaa agaagataac cttttttcaa aacaacagct tttattgctg
     6601 caacgacttc tggaatcgat ttgccagtcg tatcgatacg aacagcatcc tctgcttgct
     6661 tcagcggaga gacgtccctt gttgaatcat aatggtctct ttcctgtatc tctttcgtca
     6721 gtgtttcaag atcagtcgga attccttttt cttggttctc tttgaaacgt ctttctgcac
     6781 gctcacttac gcttgctact aaaaagattt tcacttctgc attcggtaat acagctgtcc
     6841 cgatgtctct tccgtccatg acaacgccac cgcgttcccc tatttttcgt tggacagcaa
     6901 ctaattcttc tctgactttt ccatgtgcag agacttcaga aacagctttt gtgacatctg
     6961 gttgacggat ttctaaagtc acatcttttg atgctatgaa tacatgctgt ccatcttctt
     7021 gttgcgaaaa agagatagga tactttttga tcagcgaaac tagcccttct tcatctgaaa
     7081 aagatacatt gttcgtaata gctaaataag ttactgcgcg atacatggca ccggtatctg
     7141 tataaatata attcaattct tttgctaata tcttggcaac ggtacttttc ccagatgaag
     7201 caggcccgtc gattgcaata ctgatttgtg tcatgatata actccttttt ctcagaaaaa
     7261 aagccgcaaa gcgcggctat tattatttaa ttcttaattc ttgaccaggg taaagcataa
     7321 agttgtttgg atctaagcca ttcaattcaa acaattgatc agtggtgatc cctgcacgct
     7381 cagccacttg ttttggacct tcgcctgctt gaacagtcgt tgttgaaccg gctgcagctg
     7441 atgaagaagg tgttgtttct gctgcattgc tgcttgaatc ccctgcttga taagttgcct
     7501 cacttgagga agtcggtgtt gtctctgctg caatactgct ttctgacgtt acacctgtat
     7561 cttgagacac agtagattct tccgcgattg tactagattc tactgttgaa gtctcagttg
     7621 actcctcttt tgttgtactt gtagaacttt ctactactga tgtcgaagtt tcagaagaag
     7681 ttgctgctgt tgcattgttg cttgatccat ttctgatcca gaaataagca cctgctggaa
     7741 tagcgataca taagaccagt aaaatcaaaa atagcgaaag aaataatgta tttcctttct
     7801 tttgttgtct ctgagaactt cttgatgaaa cttcatcatc tgtatcgtag attggttgtt
     7861 cccatggttc ttgtgtttcg ttattttctg tagattgatg tctatctttt ctgctcactg
     7921 ttttacctcc taaactctat cgtgtgtatt ataccatagg aaaaagtgtc ttgtcctaaa
     7981 aaatcaatgt tccatgtttt ttttaaataa atttagtaaa atcgttcccc aatgaagttg
     8041 ttcagtctta gaaaaaagct tcctctttgg cagaagttct gcttttgctc catcaatatc
     8101 acaacaattc tgcggctttt cggagagttt ttcgccaaaa taagctaaga tgaattttct
     8161 gcggcagttt tcttcattaa tatagcgaag catctgctgc aggcggaatt ctttttcttt
     8221 ttcctgacgt ttgagccgtt ccacccaatt ttctggtttt tcagactgct ggatcagctc
     8281 catccatttt ttttgcagct catcaaaggg agcttgctct gtggcatatt ccaaataaag
     8341 ctcaaaactt tgtcgctgtt ctctagaaag ttgattaaag aaataatgga tacgttcatc
     8401 cccactttga taaaaaagaa ttgctgcact ttcttcctga tctctgcctg ctcgaccgat
     8461 ttcttgtaca tagttttcta gactgtctgg caaatcataa tggaccacat aacggatatc
     8521 agatttatcg atccccatac caaatgcatt cgtagcaatg agaaactgca gctgattttt
     8581 tacaaactgc tgttgaagtt gtcttctttg agctgcatca agaccaccgt gatagtatcc
     8641 aactgtaaaa cgttccctga ataaatgata caatcgttcg acttcttttt ttgttgcaca
     8701 ataaatgatt gccgctcctt gtgctctttc catgaagtgt tcaagttctt gttctttttg
     8761 ctgcgttttc cgaacaaaaa gcgagatatt ttgccgattg actgattgtc tgatctcttt
     8821 tggtggtcga tcaaatagta catgacgtat atctcttgct actaaatctg ttgctgtcgc
     8881 cgttagtgcc agtgtgaccg ggtttcctaa aagctttcgg atttttccta actgttgata
     8941 ttctggacgg aaatcaactc cccattgaga cacgcaatga gcctcatcta ctacatataa
     9001 cgcaatattt tgttttttca gatgctctaa aagagaagga ttagtcaaca tttcgggact
     9061 caaaaacaaa aatttatatt gcgatagatg acggaggacg tatcttcttt cagattgcga
     9121 aagtaaacta ttgaaagcag ctactcgttt ctcccctcgt ttttgtaatt gcgtcacttg
     9181 atcttccatt agagaaagca gcggtgacac gatgatgacc agaccttcca ttaaataccc
     9241 cgtcaattga tagcaaaggc tttttcccgt tcctgtaggc aaaatagcga gagtatcttc
     9301 tccatcaagc aacgcctgaa taatttcttc ttggccggga cgaaatgaat caaatccaaa
     9361 atattttttt aattcattta ttaacattct gtatcgcttc ctttctcaat agatagattt
     9421 gatacaaacg aaattctcca taatctaatt gtccatctac attccattcg ctaaagcgcc
     9481 actctcgcac ggaatcctta tttggttcca aacgttcgat tgtttctgca gagagaatcc
     9541 actcgtatgg aaaatcatca aaaaacaagg cccactcaat aagatgatct gttactgttc
     9601 ctctttttaa atgacggatt gccatgatct ggtcaattgt ctgaccattc ataaacatct
     9661 gcttggtgat catcatgctt tgattgaaat tttgctgtaa taatgaatcg atcaaagcgt
     9721 gccaaagcga atctggccgt ttttcgattt gtgctaacaa aaggtggata catctgcttt
     9781 gttgcagata aaccgctgac tcatcattgt tttttgccag ctgataagga agcagccctg
     9841 ttcgctcatt tccagataat tggttagcta aaaaatctgc tgcttcttct ggtatctccg
     9901 aaaacagctg caccaaactc tcatacgcag tatcaatcaa aatttcacgt ggcaattggc
     9961 tttcactaag ccattttttt agttggaaag tataaaaagg acttgtctct gctggaagat
    10021 agtcttgaat acccgttgcc agattagaaa ttacttgaac agcaaattta atgagccgcc
    10081 aactagtttc ccctgttctg ccatagcggt caaaacgcaa accagtatgt tctatttgat
    10141 gttcggacaa catatcagcc cctgcaggcg ttagctttgc ttcattttca tttatttcga
    10201 tccaaccttg ctgcgcaatt ttttgcaaaa tttgataaaa cttatcctgc ttcaattctg
    10261 gaaaactgtt atggataaac aaaagttcgt gggtaaatcc ataaataagt actgaagtcg
    10321 ttcgttttcc cacaaggagt tggtaaagag aactaatccg cagcttgtgt cctgatgaaa
    10381 atagcgataa aataaaaaca atcatattat tctccttaag ttaggatggt tagaaatgtc
    10441 actactatgt aaacttgtac ctgaacgctg tattgcatgc ggtctttgtc aaatcgaagc
    10501 gccagatatt ttcgattatg atgaagaagg aatcgtttta tttgcccaag aaccagaggc
    10561 tcatcaacag ttcgtgatgc cggaagaaga aacatatgta aaaaaagcgt atcaaaaatg
    10621 tccagttcga gcgattttat tagaaaataa aatataaata taaacgaaac tttaaaaacg
    10681 tacactaagt tctctaaact tgaaaataag ccgggatctg tttctcttgt tccgtgaaat
    10741 cccgacttat tttgaaagat tcatttgcta tctatagtta attgactagt tttttcacgg
    10801 accctatagg acccatttat attatttcaa ctttttcagc cagttttcca atgtattgac
    10861 gatcacagtt tgctggtctg cgttagaaat ttctgcctct ccatctcctt tttgctcacc
    10921 atagctgcca aaacctccat gatttccgcc attgattgat acatactctg ttctttccgg
    10981 taaatactgc ttagcttctt gataagcttc ctgattcaat actttatctt ttgtcgccgt
    11041 gatcgataaa acaggaacag ctgattctgt caatgttcct tttttgtcgg gataacttgc
    11101 catgaagaat acccctttta aatgtttgtc tgaatgattc ttattgacat aacgacttgc
    11161 cattacgcca cctaatgaat ggccaccgat cacataatcg gaatttggaa aatcttcttt
    11221 gaccttatcc gctttgtttc cgcccatcac tgctagatca agtggcattt tgacaatagc
    11281 gactgaaaag ccgttttttg ctaaatcttg cgcccaaata ctataacttt ctggctctac
    11341 gagagcacca ggataaaaaa taagtaatgg agactttcca tgattctttt tctctccttc
    11401 aaaaaataag taatcttctt tgttttttcc ttcttttacc aacacttgcg cttctgacga
    11461 tggttcgtac gtattttgct gtatatagta ataaccggct ccaccgagta atcctaaaat
    11521 gatgactaag ccaattagta ttcgtctaaa tattttcact ttctcccacc ttttctatct
    11581 gagtgacccc tttttcttaa tcaagtatga ttatacctta aaaaaataag agagaaatgc
    11641 aaactttcca gcatcaaata aaaaaagacg gaatatccat ttgaatatcc gccctttttg
    11701 tatgtttatt tttatttagc acataaacga tacacagctt ctgcataaat ttccattgct
    11761 ttatacatac tacttaattc ccatcgttca ttcgcctggt gcataaagtc aggagtatca
    11821 gggaacatcg caccgaatgc cacacactgg ttcatcgtac gagcaaaagt agcgccgcct
    11881 gatacaaacg gttcagtcat gtctccagta atatcgcgat atgtccccaa tagatttttc
    11941 actaactcac tgtctagtgg cacgtataat gaatcaagga agtcaaattc ttcataagtc
    12001 aacccatatt tttctgctgt tttagttaat ttagctacta aatcatcttt cttgaatgta
    12061 acagggattc tcatatctac accgattttt gtttgttctg gtgtgatttc caaacttgca
    12121 aagttcatcg ttagctcgcc ggattgttca tcttctgttt tgcccacgac agcttcacca
    12181 gttgcatttt cttgaactaa ttttcctaag aaattgattg ggccaaaatc aaatacttct
    12241 gaaagagcaa ttgccagacg agaaatagca ttcactcctt gtgctgcatc tttcgcgtgg
    12301 atacttttac caagaacgac gatgccttca ccttgttctt cgaaatcgaa ttcgtgtttt
    12361 ttcaatgctt cttttacttc agaaagcttt tctccagagt aaggagctgc atcaggaaca
    12421 acattcaacg ctcctccagc ttttacagaa aactcgttcg ttcctggtcc tgtcaagtaa
    12481 gcttgcaata agcctttttc tgcataaatt aaaggaaatt cagcatctgg cgcaaatcct
    12541 tgcgtaattc cttcttcttt ttcgttatat ttttctaaac aacgccataa attttcttca
    12601 tctgtaccaa agataaaacg aatacgtgtc ttgaattcca cgccagcatc aatcaaagct
    12661 ttgacggcat acattgccgc aatagaagga cctttgtcat cttgggatcc gcgaccaact
    12721 aaccagccgt cttttatagt tggatcgaat ggttttgttt cccaattatt ttcgtcccct
    12781 gctggaacaa cgtccatatg acacaagata ccgaataatt catctccaga gccaatctct
    12841 gaataaccgt aatagccttc tggatcttta aatgttctaa atcctagctt ttcactgatt
    12901 tccaatactt tatccaaagc ttcaatcact tttttaccga agggatgtcc ttgtcctgaa
    12961 tctgcttcat ctagtacgga aggaattcgg atcaattcgc tcaatgattc taatgcttgt
    13021 tcatgatgtt gttctgtcac aaattttttc atgatattat cctcctaata tgttaaaaag
    13081 ggtcatgtca aattcctccg acacaacctc ttcttctcaa ataatgacgt tttaagcctg
    13141 ctccatcagc aagcagaatg ttcttaacaa atgatgaaag aaaaaacact cactgaatgg
    13201 agctattgac ttatccacgt gcttatcgat agccgtttat cggtttcttc attcttatga
    13261 tagaccttgt acctgtattt gtctaggttt agaacattgc tgctacacct aggatcacac
    13321 agatggctac aaataatatc gcaattaatt taccggtaaa tttccaccac actgaaacat
    13381 cgaaacgagc aattgctaca gcacccatta cgatagcaga tgttggtgta attaagttta
    13441 ctaaaccaga tgcagattga taagcagtga ttactaaatc cttaccgacg ccggcaaatt
    13501 cacccatagg tcccatgatt cccattgttg cagcagctaa gccggaagtt gaaggaatca
    13561 agaatgacat agggatatag aaaataaatg taataatgat gaatacactt gaagataatg
    13621 aacttaatcc ttgttcgccc caatgtaaga tggtgtctgt gattaatcca ttgttcataa
    13681 ccacttggat accacgagca acagctacta cgattgctac accgatcaaa tcagaagcac
    13741 cagctaaaaa ttcagagaca aattcagact ctttcatgcc ataagtgatt gctactacga
    13801 tggacattac taagaataac atagtaattt ctgggaagta ccagtcacct aatggaagca
    13861 tgcttttacc tagaaccgta cctagtaccg gaaggtttgt taaccagttt gtcaatgatt
    13921 caaaaatcgt gaaattcgca ttcaaggttg tccaaggaat caaactgatg atcatgatac
    13981 caaaagtaat aaagaacaat acattaacat gtttttgttt tttcgtgatt acttcttgac
    14041 gaccgattgc ttcaatatcg aaatgcttca tatcttcttt acgttggttg tatactaatg
    14101 attttgttgg atctttttcg atctttgatg cataacgata cacatataca atagaaatag
    14161 ctaacaaaat aacgaacatc aagaatcgaa gaccaatacc ttcacccatc gaaatcccaa
    14221 cagcttgtga agctacgcct gttgcaaaag gatttaccgt tgaagctaga cagcctactt
    14281 gagaccctac taatacgatt gctacagcta ctactgtatc aaagcctaca gccatcatga
    14341 ctgggatcag taaagcatag aatggaatcg tttcttctgc cattccgtaa gtagagccgc
    14401 ctaatgcaaa taacagcatc aatactggaa taagcatttt ttcttttcct ttgaatttct
    14461 tcacaactga agcaatcccg gcatctagtg cccctgtttt gttgataata cctaaaaatc
    14521 caccaacaac caaaatgaag aaagagattg ggattgcagc aggtgtttct ttagttagct
    14581 cccccgctgg tacacctagc atcccattga ttggcgccat gaaaatatcc cacagccctt
    14641 gaggattttg ttgtactcgt tcatatgatc cagcgacgat gttgcctgca tcgtctacac
    14701 tatagtgccc agctggtata aaccaagtaa gtacagcgat tactgcaata ataataaata
    14761 agaccgtata cgctgaaggc atttgaaatt ttttcttttt tgtttgttcc atcttcttct
    14821 tcctttcttt tccgttagag acaacaattt tggctctaat gttattttat caaaaagagt
    14881 atcagaacaa aaataataac acgcattttg taaaactttt gttcaaaaag ttcgtttttc
    14941 cctattccct cctctttttt caggttttta aagctttctt ctttttcatt gtagcgtttc
    15001 ctttttttta taaacaaaca ttttcgtctt ttaaaaggag aagaatttca catttgcaaa
    15061 gaattgattg atttttatgc ataaatcaaa aaaatactca aaacaaacaa ataaaacgtt
    15121 tacattattg catgtcttgt atttttttcc aaaaaaaaag accaagaaat ttcttgatct
    15181 ttttgatatt tatttgactg ctgtatgacg ttgttcgaac tgatgttgtt ttcgacttaa
    15241 ccatggaaga agttgcgcat gcagcactaa aaagacagca ctcacgatga atcctttgat
    15301 caagttgaaa ggaacgatcc caatcagtac atagtttgct aaagacatgc ccagcatctg
    15361 tgttgcgttc agccctaaaa acattaagta aagaggcgta ataacgaaat aatttgcgat
    15421 actcataaaa atagttagag cgatggttcc tgtaatgaca cctaaaaatt tgtttcttcc
    15481 tttatgctgt ttctttacac taaagaaata ataaatcggg aatgtaaaga tcgttgttga
    15541 taagaaacta gcagtgtctc ctaccaaatt atccggagaa aaacctgtag tcagcagatg
    15601 taatactgaa cgcaagaacg ctgttgcaac tccggccgct ggaccgaata agaacatgct
    15661 gatcaatacc gagatatcac taaaatcgat cttcaaaaaa ctaaaagccg gcatgatcgg
    15721 aaaagcaaaa tactgtaaaa ctaatgcgat cgcagcaaac atcgctactg caaccatttt
    15781 ctgtacacgg gtgttcttca tttgaaatcc tcctgttagg actcctcttc agcgaacttt
    15841 ttgacgtttc tctccaaatg aaaaaactct attttccagg gaaaatagag ttagagttat
    15901 ttgatcaagc gtcgtcaaat aagctctatc ttctttatcc agactatact gtcggtatcg
    15961 gaatttcacc gattcagcta tttttttgca aaataggtcg tggactataa ccaccggtcg
    16021 ggaatttcac cctgcccctg aagacgaacc ttatataatt tttgtttaca tattcattat
    16081 acatatctat tcaaaaaacg caacatctaa cacttataaa aagtaagtgt tcattttgag
    16141 tggttcagca aactgctgac ttcttttttg ttcagttcac ggtaatcccc aggacgtagg
    16201 ccttgtaaag tcagatctcc gtatttttca cgttttagtt tttgcacagg aagaccaact
    16261 gcttgaagca tatttttcac ttgatgatta cgtccttcgt ggatcgtcaa ttccacgata
    16321 ctgtggtttg tcttaggatc cactgataaa atttggaatt tagctggaga tgtttttcgt
    16381 ccttcgatct ttattccttt tgtcaaaggt gcaagcatcg attttgtagc gatccctttt
    16441 acctttgcaa cgtaaacttt atccacttca tgttttggat gtgtcaggcg ctgagcaaaa
    16501 tctccatcat ttgtcagtag caagatcccc gaagtatcgt aatccagtcg acctacagga
    16561 tagatacgtt cttttaccat cggcaaaaga tccgtaacaa cttttcttcc tttgtcatct
    16621 gcaacagcag aaataactcc tttaggtttg tacaataaat agtaaccgta ttcttcttga
    16681 taaattggga cttcatccac ttccacagtg tcatgtttcc caacttttat ccctaattcc
    16741 cttacaactt gtccgtttac ttttacacgt cctgcaagga tgaattcttc tgcttttcga
    16801 cgagaagtga tgccagcgtg ggcaattact ttctgcaatc tctccattac aattattctc
    16861 ctttattcat tccatcaaag aatagatctg gtgacacgtc ttcttcaagt gaaatttcca
    16921 tttcttgtgt atcaggcagt tcttctaatg atttcaaacc aaaataatct aagaagtagc
    16981 cagttgttcc atataatatc ggccgacctg gtccttctac tctacctttt tcttcaatca
    17041 gtttatgggc agctagacgc tgtaccgctc ctgaaacctg aactcctcga atctgctcga
    17101 tttcagctct tgtgattggc tgtttataag cgatgattgc taaggtttcg acggcggctt
    17161 gagataatgt gtttgatgtc ccttgcgcat atcgcttaag taagggagcc agctcttttt
    17221 tagtcgttaa tacataatgg ctttccgttt caaaaatatg caaagctgag tgcgagtttt
    17281 gagtgtaaga ttcttttaat tctttcacta aacttgtgac ttctgcttcg ctgagattta
    17341 acagtccgct taattcttca ttactgatcc cttcctcgcc aacaataaaa agaagggctt
    17401 caagttcact taatttcgtc atgttcggta tctcctactg ctggataaag cataattgat
    17461 tcatagtttt ctttttgttg cgcaatgatc tgcccttttt tcatcaattc tagcaaagcc
    17521 ataaaagtag tgacaacttc acttttagaa ggtgactcaa aaaaagaatc gaaagtacag
    17581 ccatgcgcat ttctttttat acgctcttcg ataaatacca ttcgttcttc gatcgttgtg
    17641 tcatcgggcg tgatcgtttt ttccactttt tgagaaaatt tcttacgttc taagattttc
    17701 tgcatggcac ggatcaaatc gatttttttg acttgtcctc gcttcaacgg cttttcagca
    17761 tccgctaacc catcgatgtt cataggttct tttgtgtaat aaagacttcg ttcctctgct
    17821 ttttctgtca gtctttcagc tgcatattta tatttacggt attctaaaag ctgagtgacc
    17881 aattcttctc gaggatcttc ttcccataat tcttcatcgt ctgtgacgaa ttcttggaca
    17941 ggaagcaatg tcttgctttt gattgccatc aatgtagcag ccatcactaa gtattctcct
    18001 gcaacagcta gctcgagtgt tttcattgta tggatataat tcatatattg ctccgtgatc
    18061 gtagcgatcg gtatatcata tatatcgatt tccatttgct gaatcagatg aagcagcaga
    18121 tcgagaggac cctcgaatac atctaattta atattgatct ccgtcaactc attcactctt
    18181 tcttcttttt ctttgctagc cattttccaa tgtaaggctc tgtgatttca gttgcacgga
    18241 tggagacatc cgggtacttt tcctgtaatt catctaacat ttgaaagccc atattctcac
    18301 cgcgataaga cggattcaaa gaaatgtcat ggatgatcag ctgatcgttc gttgcccagt
    18361 aaataccaat aatcccttga atgttggttg aaccttctgg cgtaaagaaa aaaagttcat
    18421 aatcgtcttc agattcgtac gtatcaatct ccttcaacaa agaagtttta cctgtcagtt
    18481 tcttatggaa actcaatagt cccatagcaa ttttacggtt ttctttccgg taatgtgtta
    18541 acatcttctc accttcctat gactaagccc ttggaaaatg ctgcttataa acatccgtca
    18601 ttcttttctt cgtgatatgt gtataaatct gagtcgtaga gatatccgcg tgacctaaca
    18661 attcctgtac tgtccgcaaa tcagctccat tttctagcag atgtgtggca aagctatgcc
    18721 gcagcgtatg tggtgttact tctttgtaaa tcccagcctc tcgtactaac tgcttcagat
    18781 ttttccagat tccttgccga gaaagacctt tcccatgatt attgacaaat acatgcattt
    18841 cagatgcgtc ctttacaagt aatggacgtg cttcgtctaa gtagcgttcc agccattgga
    18901 tcgcataatc acctaaagga atgatccgct ctttatctcc ttttccaact gtctgtacca
    18961 gtccaagaga aagatgaaga tctcccaatt tcaatccaat caattcactg acgcgcatcc
    19021 cagtagcata catgacttcc aagattgcac gatctcttat ccctaacgtt tttgtcgtat
    19081 caggtgcttc aatcagcttt tctacttctg tcagagtcaa tgtacttggt aatttctgtg
    19141 ctttcttcgg cgtatcgata tgttgcatcg gatcatgatc agtgatacgc tcttgccgta
    19201 aaaactgatg gaatcttctg agacttgaga tcatccgagt aacagttgct gtcgcttttt
    19261 tttcttcatg caacttctcc agaaaacgga tgactaaaaa gcgatcgaca tcctgccatg
    19321 aagcaatttt ctgctcctgt agaaaatgca agtactgttc caaatcacgt tcatagcttt
    19381 gtcgtgtatt ggcggacaat ccccgttcaa tattcaagta gtggagataa tcgttgattt
    19441 gctctttcat aataatcccc ctcatgcctc tctatcatat cagataccgc ttcattctga
    19501 tagtcttttt ccataatctg agcaaagaaa aagccgtcta gacactcaga cggactggtt
    19561 tcttttttct ttttcatagc attcctgaca gattccatgg aacgttagcc gatgatcttt
    19621 tactaaaaaa tgataacgtt cttctactac ttgctccact tcaagtaaaa gatcctcttc
    19681 tacttcctcg atcgtgccgc agttcaagca tagtaaatga tgatggaaat gtttggcgcc
    19741 ttcttttctc aaatcataac gggctaatcc atcattaaaa cttactttat cgacaatttt
    19801 caattctgtc aagatttcaa gggttcgata aacagtagca agtccaattt ccggactctt
    19861 ttttttcact aaaaagaaga tttcttctgc agataaatgc tctttctcat tttccaaaag
    19921 cacaagcaga gtagcttctc tttgcggtgt cagcttaaac cccgcttcat gtagctgctg
    19981 ttttgttttt ttcatcgccg aaatagcatt catgaccatt tactcaaccc caacaattta
    20041 taataattac aaataaaaaa agatataaca ctatgttaat taaaattatt ataagctagt
    20101 taagaaaaac atgcaaggga ttctcaatta gattttttga ctagttttgt cacaccgttt
    20161 tcttgtgtaa tcaatccttg tttcaaaaga ttacctaatg cgcgcttaaa tgctcctttg
    20221 ctgataccaa aagctttcat gatttcttct ggatccgatt tatctgtaaa gttgatttgc
    20281 tgatctgcag aacgttctaa aatggttaaa atcatttgtg catcatctga tatagcttca
    20341 tatgctcttg gcttcaatga aagattcagt acaccgtctg gtcggacacc aatcactcga
    20401 ccttttatct gctcgcctag acgaggttca ttatatcgtt cagaaggatg gataaaccca
    20461 agatagaaat cttccgttaa aacgtacgta cctgttaatt tcaagcggta tgctgttcct
    20521 atcacatctt tgtttttcat ttcttctgtt ccatatttgc ttaaagattt gaatattttt
    20581 tcatctgcta aactgcccca aatacggtct tttgcatcaa ctctaaggga aatcatcaag
    20641 cgatcccctt ttttaggcca tagctctgtc attgtcggca attcatcaag agatacgaca
    20701 aagtctttat ctggaagacc gatatcgaca aacgcaccta aatcttttcg tgtagcagta
    20761 acgattccaa aagcgtaatg accgatacgg cttttaggaa tttgtgtagt gatccgattt
    20821 tcatgttttt gattttggta accgaatcct tcaactgctt caccgatttt gtgttcacct
    20881 tctgatttgc ttaagccaaa ggtttgtccg tttttttgga caaagtagtt tttttcattt
    20941 tcatcaataa taatacctgt aaatatagtt gctaataaat cgttcatttt tttctccctc
    21001 tatagtgaaa ggttttctta atacatttct ttgctatcat aacataatgt tatctacttg
    21061 aatagctgag ccttggtttg gaaaggtgaa aaaaggagta tgacaacagt tgtgtcatac
    21121 tccccttttt cgaataaacg gtgttaaacg gcaggctcac agcctctttc atttgcctaa
    21181 aattaattgc tcccatttcc tccgaaccat ccagttttac agttgatggt tacgatgtaa
    21241 aatggcaaag cactttctcc aatgcctttc atcaatgcag attttgttga agtggcatat
    21301 agattataat agccttcccc attttcgatt ctggcttttt ctaatctgta acctccttca
    21361 acgatatatc cacgttggat acatgtagca atcactttgc tttggacacc tggtgcccac
    21421 gtccatgctg gattagatgc atcggcaata tcacttgctc tggcagattt gattggctga
    21481 ttcgctgagt ttgaagagga aggggtcgag gatgccgctt cttgctgtgc tgcttgtgcg
    21541 accgcagctt gttgagcggc ttgagctgca gctgctgctt gagcggcttg ttttgcttgt
    21601 tcttcagctg cttttttcgc ttcttctgct tttttctttt cctcttcttc ttttttctct
    21661 ttatcagtga gcatcttatc tacttgtttc aattgttcat tcaactgagc agatagatct
    21721 gtatttttca ctttttctac tgcttctttt gccgtcttgt attggtcgcg tgttgctgaa
    21781 tccactactt ttccgtcttt aaagactata gctgtttttt ctttagctgt ttgcaattca
    21841 gcatattgat ttttagcttc tgtttgtgct tgttgaatca attttccaaa atctgtgtta
    21901 tccgtttcga ttgcttggat ctctttatct gctttcaact tgatgtcatc tgctagatga
    21961 tcatcgacga tggcaggtgc tatgaaccac tcattcactt tttggatatc tcggatctta
    22021 gattggatat cttggtaagt tgtttctaac tctgaatatc ctttttcatt cttaagactg
    22081 gataaatcat tttttagttt tgataaatct tgatgaatca tatctgcacg aataaattga
    22141 tggtgatcat ctgtataaaa ggcagcaagt ttctcatgaa gttcttccat ttgttgctgt
    22201 ctttttgctt ctgctgctac ttcggcttct actttttgat gatggtcata ataagcccag
    22261 cttcctccac cgagtagaag tactgctgct aaaacgagat aaggtacttt ttttgatttt
    22321 ttcttttgcg ctttatctgg atctgttttt tctaagtttg attcttgatg tgttttttca
    22381 gtatctggca cgattgttat tgatttcgct tctgcttcaa acagcttagg ctggttctct
    22441 tctttttcta tttttgcttc aagatcagta ccctctttgc ttacagattg attttcagca
    22501 tcggattcac tatttatttc atcgggctct gttgactttt tgtctgtgtt ttcgagtatt
    22561 tcttttttct ctgcttccgg cagtttattc gttttttcct tttctaattg tttttcagta
    22621 aatacttcag ttttttctgt gatatccgtt tttacgtctt ttatttttac tgtttcttta
    22681 cctgtggcgt tttctctatc agagtctttt tcagtttctt gttccttttc tggctctact
    22741 ttgttttcct gtgcaatttt ttcactgatc attttgagca gctctttcgc gtgctcttct
    22801 tttgtatctt cacgatgtgc tttgatataa gcggatagta tcgaattttc ttcctcatta
    22861 tcgacgattt ctttcagttc agctactctt cttttttgtt ttgattcaag cgtttcttct
    22921 tgattctttc ctgattcttc cgaagtctca tgaacagttg ctttcttctg ttcatttttc
    22981 tctatattag ttacttgatc gtgagcaggt ggttcttcgt cttctggttc tgctttttcg
    23041 aataattcca ttacagattc tagaggtaaa tctttcaatt ccgaccattc gattggatcg
    23101 tttaattctg tatcaggaaa gactgcatct tcagttgatt tatcctgcat agctgcatct
    23161 gtatttgttt cttcaattga ttcttttatt tgctgatctt ctgcagttat ttgatgaccg
    23221 cagtctggac agatagtatt ctgctccatt tttttcgatc cgcaatttgg acattttttc
    23281 atcacttagc gatcggctcc tttactaggt ttacgctacc atttaatcta tcatattcta
    23341 tacgtcacgc caatagctta tttttaggat ttacttaaaa ataatgaatg aatttccttc
    23401 ctatagaaaa aaaagcttga gactgcgtag tctcaagctt tttttctttt aaaataaacc
    23461 aaacagtttt actgatttct cttctggtca atagtccacg cttattctaa gaaatctttt
    23521 aattgttttg aacgagaagg atggcgcaat tttcttaatg ctttagcctc gatctgacga
    23581 atacgttccc gagtaacacc aaatactttc cctacttctt ccaatgttct cgtccggcca
    23641 tcatctaaac caaaacgtaa gcgaaggaca ttctcttccc gatcagtcaa tgtatctagt
    23701 acatcttcca attgttcttt tagtaactca taagctgcgt gttctgctgg acttgttgct
    23761 tcctggtctt ctatgaaatc acctaagtga gagtcatctt cttcaccgat tggcgtttca
    23821 agggaaacag gttcttgcgc gattttcaag atttctcgga ctttttctgt tggaagatcc
    23881 atttccgcac cgatttcttc tggcgtaggt tctcttccaa ggtcttgcag caattgacgt
    23941 tggatacgta tcaatttatt aattgtttca accatatgaa ctggaatacg gatcgtacgt
    24001 gcttggtcag cgattgctcg agtgatggct tgacgaatcc accatgtagc ataggttgaa
    24061 aacttaaatc ctttgcggta gtcaaatttt tcaactgcct tcatcagtcc catgtttcct
    24121 tcttggatca agtcaaggaa ctgcatgcct cgtcctacat aacgtttagc gatacttact
    24181 actaaacgaa ggtttgcttc tgccagacgc tgtttcgctt cttggtcgcc ttcttcgatt
    24241 ttcaatgcta acgctacttc ttcttccgca gttaaaaggg agacacggcc aatttctttc
    24301 agatacatac gaaccgggtc attgattttt acaccggttg gcgcagaaag atcttctgtt
    24361 tttgcttgtt cagctttttt ctcagcactc ttcaagctgt gaattgatgg atcaccattt
    24421 tcatccacca cactgatacc tgcgtcttca atcttttgga tcaatttgtc catttcatct
    24481 gcattcaaag tgaatggtgt agcaagctga ttggataaat catcatatac aacttgtcgt
    24541 ttgggtttgt tttctttgat gaaagctgct actgctgctt catacgtttt tttatctgtt
    24601 ccatttgcca taaaagaagg ccccccttga gtagctattt ggcttgtttt aactgtttcg
    24661 ttaaattgat gatttcaatc gtcaattcaa gctcaagctg tttgtttcca gttcgtctgg
    24721 cttcttgctg catttgtttt tttaatgtta tttcatcagc taagccagat ttgctgatca
    24781 catctagcaa gtcttggatt tctcgtggcg aactttcttc tgccaccggt aaatattcga
    24841 tttccaccac caaccgcctt aaattttcat cttgcaaaaa gtctaaaaac tctgcaaggt
    24901 tgaattcata atgttgtgag acatatgcat cgaataaaaa ataaacttct gcatatgcat
    24961 catgaataaa ctgaaattct cgttctttta aaatattacg gacagaaact tctttaaatg
    25021 cacgatataa tagaatctgc tctgcctttt ctacttgcgt caaaggtctc tttttccgtg
    25081 cagtttcttg tctcgtaacc tgagtgtgtt gactttcctg aggttcttga cgattttgct
    25141 gatttgtcct tcgaagatcg cgcagttgtt tttgtatcgt ctctctgccg atctgaaact
    25201 ctgttgacag ttgagataga tacatatctt gttcgattgg tgaaacaact cggctaagtt
    25261 caactagtaa ttcttcgagg tattcgatct tgtctttttc attatctaaa tttttccctt
    25321 gttttaaata acgtgattta aaagtaaaga ctgtttcgcg cccatgagcc actaattctt
    25381 ggaaagatgc ttctccatac ttacggagat attcatcagg atcaagcttt tctggaacga
    25441 ctacgacaga aagtgctaat cgactgtttt gccgaagcaa ttcaatccct cgattggttg
    25501 cttcaaaacc tgcgttgtct ccgtcatagc aaaagaccaa ttctttcgtc agcttttcca
    25561 tttgttggat ctgttgagct gttagacttg tccccataga agctaatcca gttttgatac
    25621 cagcctgcca tgcagcaatc acatccataa acccttcgaa caacaaaatt tctccgtttt
    25681 tccggatatc gcttcttgct ttatcaagat taaataaaac ttgtctttta ttgaacagtt
    25741 ctgtttctgg actattcaag tatttgggct gatctttttc ctgccctttt tcaggtgcaa
    25801 gccagcgtcc tgaaaaaccg atcgtctggc cttgagaatt acgaagtgga aacatcactc
    25861 tttgataaaa acgatcagac atacggccat catcatgcgt gacaaacaat ccagagcgtt
    25921 ctaacaattc atttgaaatt gattcattct tgaatacttg ctgaagaaaa gaacgctcat
    25981 taggtgcaaa acctatgttg aattcttcaa ttaattctaa agacaaccca cgactttgca
    26041 aatattctaa agctggctgt ccagcttttg tatgcaatag catgtgatga tagatttccg
    26101 ctgctttttc atgagcagca atcagtttcc ccgtagcaga ttcaggattt tggacagcta
    26161 tagtacgctg acgccattga tcttctaacg gtatctgttc gaagtctgcc acttttacca
    26221 ctgcttctgg aaaacttaga ccttctagtt cttgaagaaa agtaaacacg tttccgcctt
    26281 taccacaacc aaagcaatga aaaatctgct tgtcttctgc aacagaaaaa gacggtgtac
    26341 gttcttcatg aaaaggacac agccccaagt aatttttacc agactttttc aactggacat
    26401 attgtccaat cacctcaacg atattcgttt gactgcgtac tgtttcgata acctcttgag
    26461 gaatccgttg agccattttt tcaccccctg ctctattgat atcttttggg tttaacagaa
    26521 gatatttcag gagaataacc ggtaaaaaat cgcactaact gaaatcagtg cgattttaaa
    26581 ggacacaatt atacatgttt gattgtatca tatttcattg ctttttcaag tataacacat
    26641 ttctatctca ttaagcatca atttgctact cttttcagta actgattttg aatatcagcc
    26701 ttccagtaca atactcgaag aacaatattt acgagcatga atacaaagaa gtatcctacg
    26761 ctctctccca accctaagtt tacttccaaa attccatgga acagcattgc agctacatat
    26821 atccctacga tcgtcgttac tgctaggaag atgcgcaatg ggttgaaggg ataacaagct
    26881 tttacaactg ccatgcaact gatcccaatc agcaagtaat acatcaaagt agtagtttca
    26941 gcatttcccc atgcgaatgt ttttccaagt agatacaccg caatgatatt cactactaca
    27001 agcaaggcat ttggtaaagc attaataagt gctgtaggca aataacggta agtgattttt
    27061 cttttatctt gttcaaaaga taaaaagaag gaaggatacc cttcaatcgc taaatcaatc
    27121 agcgtgattt ggatagggat aaacggaaat ccaattgctg taacggcaca tataatcgat
    27181 aaaataaatg aataaatcgt tttgataaaa aagatgcctg agactttcgt cacattgttg
    27241 accactcggc gtccttcaaa caggacttct ggcaatgtag taaaatcaga gtccaacaat
    27301 accagattcg caatctgacg tgttgctcca tcaccttctg ccatagcaat gctgcaatct
    27361 gcttctctta acgccaaaac atcattcaca ccgtcgcctg tcattgcaac cgttctgccg
    27421 ctttctttca attcatttac cagcaatttc ttttgctgcg gactcactcg tccaaaaacc
    27481 gtatagcgat gagcagcttc tcgcacttcc atttcttcag taatttgaga aagatcgaca
    27541 tacgcatcat aattcggtaa tcctgcacgt ctagcgatat tggagacagt aaaaggattg
    27601 tctccagaaa tcactttcag atccacacct tcctcatgaa gataagctag tgtttcttga
    27661 gcgttttttc ggattggatc atcgatttca aacagagcaa ccggctcaac aaatgctggt
    27721 ttttcttcgt tcaattgctg atttggagcg atccccaaca taagtacgcg atagccattc
    27781 gcttgggctg tttttagact gtccggaagc cgatcttctt ccaccaaacg ttcaggcgct
    27841 cctacgtaca cgactcccag ttctggaaat tccatcgcgc cccatttgcg atcagaagaa
    27901 aatgcgactt tgtttgtcac atcataccga ttagaaagct caaaataatc tctcatagcc
    27961 cgcatagtga tgttgttatc actgctttct gccagatacg tccccataat ttctgggatg
    28021 gctttctcgt acagcggatg tagtgcttct acccgctgga tactcatttt cccttcagta
    28081 atggtccctg ttttatccaa gcataatgta tcgacatggg ccagcgtttc aattgaatac
    28141 atgtcttgaa caaggattcg tttttttgcc agtttggtta cccctgtcgt taatgcaata
    28201 cttattagca ataccaaacc ctttggaagc atgcctaaca aagctgctgc agatgcaata
    28261 acagaaattt tgatagaagc atcgcggatg aacagtgctt ccaaaaatag tatgatcccc
    28321 aaaggaataa tcacgaaact agtgaatttg gatactttgc gaatcgaatc tacaagttca
    28381 gaacgaatag ctttgtgagt ctttgcctcg ctagtcaagc ggacagcata attatctgca
    28441 cctactcgga taacttcagc catgacagaa ccgcttgtca aaaagcttcc agaaagcaat
    28501 tcagctccag tttctttgac aatcaaatca gattcgcctg tcaaaagagc ttcatttgct
    28561 tctgcccgtc cagatataac ctgtaaatcg gctggtatct gttctcctgc tccgattttt
    28621 accaaatctc ctaataccag ctctttagta gaaatcgatt gttctttacc gtcccggatc
    28681 actagtactt ctgattggga aacaatcgat aatttccgta caagatttct tgcatgtatt
    28741 tcttgataaa ttccaataac gatattgacg acaataattg ctaaatacgc catgttggaa
    28801 tacgcaccta caaataacag acaaatccca ataccaaagt tcagaaaatt gaataacgtc
    28861 aatatattat cgctgaatat ttgttttgta ctttttgatg catcttcctg gtagtcattt
    28921 tgctggccag aagccatttt ctgaactacc tcttgctgtg taagtccatt cattttcttt
    28981 ttctccattt tccgccaact ttcaaaaata atcacgtgtt taagtctagc gtgttccaag
    29041 attaaaaaca acttgttttt ataaaattta tagaaaaaca cacgaatgat tttacaaaaa
    29101 agatgccaac ctttttgttt gaatcacccg tgtgctgttt ttattatcaa tctatcttta
    29161 cttatattgt tcctccaaac ggctcatcca ccaacctagt gctgtaccgg ctataaaaag
    29221 aacaggacaa gctagtaccc cagcaactcc caatcccgcg taatcggtag gaatgatcat
    29281 aatcgttgaa gcaaaaacta cacctaaaat gaaatggaat agcttgctat atgcctttga
    29341 gaaaatgtaa tccatgattt ttgacaatcc aagaacacaa agaatcccac caattccgat
    29401 cggcacaatc acttcaagtc gtacttcttt aaatccgtca gccatcgctt tatacaatcc
    29461 catatacacc aaaaaattag aagggctcaa tcctgggacg atcataccca aaccaatcaa
    29521 tccgccggca atcagccatg ttccaaaatt ctgatcgact tgcccgtcaa ataattgagc
    29581 gccgtataat aaaaacaaat aagccagaac aaaagtaaca accatgatga tcacatcaga
    29641 agtatctctt ccttttttcc ctgcttcttt ccataacgca ggaacagttc cagcgataca
    29701 tccgacaaaa aaccataata tcgttgtttc atacgcacct aataaaaaac tgactaaaaa
    29761 agaaagtaga aagatgcctg tcactccgcc tagaccaaca ggcagaaaaa acaaaacatt
    29821 ttctttgaaa ttttttgtaa ggtgggctaa aaaagaaatc agccgctcat acatgccaaa
    29881 gacagctgct aatgcaccac cgctgactcc tggcaagata aatcctgaac cgataaacat
    29941 tcccttcaca aaccgtaaca tccagtcttt ggttgtgtac cccacttctt gattttccat
    30001 tttttgcctt ttttccacta tttgcgtact ccttctttca tttaatttta ttcatgattg
    30061 aacatttcct gctattttac ttaaagactt tttcataggt ctctattatt ttttcattca
    30121 ttttgacaat atcaggataa aacatgttac ctccattatg atagagatag ccgccattgt
    30181 aaagcaagga ctggatccgc caatatcggt attgtttccc ttcctcattt cctaaaagtg
    30241 ggctcagcac atctttagaa tacgcttctg ctaattctac tgtgttttct ccgccatgat
    30301 tttttacata ggcaatataa tctttcccaa aattatatgc ttggacagct gtccataaat
    30361 cgcatccttg tttctttgct tctactatca tttccgccaa atatttgaca ccttgatcaa
    30421 tactgtcagc tggattatca atgatctcag cttctccatg cagactttcc gagctctgca
    30481 tgagatctgt cccttttcct tttgattcgg tcaatattat cgccttgatc aaattctcgt
    30541 agttttccat atgataattt tttgcagctg ttgttatttc tatttgatag ctttccactc
    30601 gttttaccga acgataagtt cttcctcata aaaacaacac cgcaccaata accgtcagaa
    30661 tgatcatgta aaaaagaata cggataatag ataatcgttt tcgcttcatt tcatcaccta
    30721 gttattttga catctttttt tatcttacta tttctttatc ttcttggcta tttcttcctt
    30781 gatttctgtg tacgccttaa gaaaaaatga attttcctgt attttttgac atcttacgaa
    30841 aatgatcgtt gtttttcagt aaaaacaatt gcccaatgac tgatataatc gttatacttt
    30901 acacagtagg tgattatgtg aaaaaagaaa agaaatatgc aaaaatgcca gatgggagcg
    30961 aaatttacta tgaaaagagc ggtcaaggct tccctctctt tttactgcat ggcaatgacg
    31021 gcagcggccg ctttttttca gaacaggtcc ctgtactcga acgctactat accgtgtatc
    31081 tagtagatag ccgaggacat ggtcgttcga caaacgaagc atctatgttg aattttcagt
    31141 taatggccga ggatctgaat acgatcatgt tgctggaaaa aatcgatcag gcagattttc
    31201 ttggatttag tgatggagca aatctagcac tggtatttgc cagcagcttc cctaaaaaag
    31261 ttcatcgatt gattttaaat tctggaaaca cgcttgttaa aggcgttcgt ttttctgcca
    31321 gagtcatcag taatattcat tatgcatggg tatggttact ctctttattt cgcccaagtc
    31381 ttcgcaaaaa tcttttagtt atcaaacttt tgctgcatga catcgggctt acagaaaatg
    31441 atttaaaaaa aatcaactcc cccactttga tcatcgtggg aaaaaaagat gtaatcaagc
    31501 taaaacattc tttgtatata gctaaaacta taccaaaagc ttcctttgtg cttgtgaaag
    31561 aacaaggaca tgaattagct agaaaagatc ctgaacgctt caatcgagaa gttcttcaat
    31621 ttctttctga aacataacta ttaggaatag aaggtgattt atttgttaaa aaataccata
    31681 caatggctga aaaaccacct aggactgttc aaaacaatct ttttgatttc tgtcattgtc
    31741 attattgtcg gtgaattgat gtccatcggt aaaactctat ctatccagca attaggagaa
    31801 acgtttgcca ctatacctgt atggaaaagc ggactaatgc tattgattgg tcttatctct
    31861 gtgttaccta tggttggtta tgatattatt ttgaatcgga tgcttgaaca aaagcagaat
    31921 cctcgttacc tgtttgagac aagctggctg atcaatacga tcaacaatat tgccggtttc
    31981 ggcgggtttg ttagtgtggg gcttcgctct gaactatatg gacaaaagaa agagagcaga
    32041 aacgtgatcc aagcattatc gaaagttttc ttgtttttga tggctggact ttctatttac
    32101 agtctgcttt cttttttact tgtagtcttc acgccagttg ctcctttttt gaagcaatat
    32161 tggatatggt tgatcggcgg cggtctatat tttcctgtcg tctttttatt tactactttc
    32221 aaaaagaaag gattccttgg tggtacctca cttaaaactc aaggacagct attgctagtt
    32281 tcattgttgg aatggaccgg tgtcctgttt agtttccttt ctgttggtta tttaatggaa
    32341 atccggattg atctgtggca aacaattcca ttattcattg ctgcttcagt gataggaatc
    32401 gtgtctatga ttccaggaga aattgggagt ttcgatgtaa tgatgattat cgggttgtcc
    32461 gctattggtg tgccaagaga aatagtcgtt gtgtggatct tgctctatcg cctgttctac
    32521 tacatcattc cgtttttgat tggaatcgtc tttttcttca aaaatatcgg ttccactttt
    32581 gatcagcgtt attctggtat ccctaaacaa ttagcaacag aaattgcgca taaaatcgtg
    32641 gttgtcttat tatacttttc tggaatcatg ctagtacttt ctgccactat cccgcaagct
    32701 tttacagagt ttcgctggct tcatagtttg aacccattga aatttcattt tattatccaa
    32761 tttcctagta tactattggg atttctttta atcattatgg gcagagggat cgcagcacgt
    32821 gtgaaacgag catatttgcc tacaatcttc ttgattgttc tagctttact ttatgtttta
    32881 ttaagtgatt ttagtttcac accggtggtt ttcttgtcta ttctgcttct gatcattctt
    32941 gcttctaaaa acgaattatt tcgggaacaa ttgatctatt catgggagtg gcgtacgatc
    33001 gatggaatca ttattggtgc actgtccttg ctttacatcg ttattggggt atacaatctg
    33061 ccggatttcc ctcatcggcg tcaccatttt atttcctttt tcttatttcc ttctgaaaag
    33121 atttggtttt cgggattgtt ggccatcatc gctgttagtt tcatgatcgt tctatttgtt
    33181 catttccttc aaggagaaaa gaaacagatt ggcgaagcct ttaatgaaga aaaggccctg
    33241 aagatcctta caacttatgg aggaaactcc gatagtcaat tgatcttctt aaaagataag
    33301 cggatgtttg cctatgaaaa agacggtgaa ccaactgttc ttctccaatt cgcttgcttc
    33361 aataataaat gtattgtaat gggtgatcct tctggtaaga aagaagattt tccagaagca
    33421 atcgaagctt ttatcgaaga aacagatcga ctatgctatt taccagtttt ctacgaaaca
    33481 agcgaagaga ttgttatgat tttgcatgaa ttcggctacg atttcattaa gatgggggaa
    33541 gaagcttatg tagacctgaa tagttttaca acttcaggga aaaaaatgaa gggcactcgt
    33601 gctgtcttga atcggatcga acgagaagga tttacatttg atgtcttaca accaccattt
    33661 tctactgagc aaatgagtac tttcaaaaat atctctgata attggttggg ttcacgaaag
    33721 gaaaaagggt tttctttagg ctttttctct gaagattatc tacaaagagc gcctattgca
    33781 gttgtcaaaa atacccaaga agaaattgtc gcttttgcaa cgatcatgcc tacttacacg
    33841 aacaataaag taggaacgat tgatctgatg cgatatgatt ctaaaaaagc accttctggc
    33901 agtatggatt tcttgttctt gcatttgttt gcctatatga aagaagaaca tatccaatgg
    33961 ttcaatttag ggatggcccc tctttcaaat gtcggaactt ccagaaagag ttttttacag
    34021 gaaaggattg catacttggt ttacgagttt ggttctcatt tttattcttt ccatggatta
    34081 agagaatata aaagcaagta cgctacaaac tgggtctcac gttatactct atattctaga
    34141 gatagttgga ttgcatatgt tatgattgct ttgctgatta ttgataatgc gccagttgag
    34201 cagacacaag gtagaataag tggtttgaaa aaatggatac gaagaaagta ttaaaaactg
    34261 cataccgata gatgaacact ctcatgatga ataaaagaga ctgaagtaaa acgaaagttc
    34321 atgcttctac aatctcttct tatacaattg aagaacaaag agcggtccaa acagaaatcc
    34381 tgtttggacc gctcttttat tttaaacatt tttcattacc aaaatattcg agtcgcgttt
    34441 cttatgcttc gatctctgta acgatacctg aacctactgt ccgtccgcct tcacgaattg
    34501 agaatgtcgt tccgttttca acagcgattg gatggatcaa gtcaacatca atcgtcacgt
    34561 tgtcaccagg catgaccatt tctgtatctt ctggcaatgt gattgttcct gtaacatcag
    34621 ttgtgcggaa gtagaactgt ggacgatagt tgttgaagaa tggagtatga cgtccacctt
    34681 cttcttttgt caacacgtac acttctgctt tgaattttgt atgtggagta atggaacctg
    34741 gtttagcaag tacttgtcca cgttcgatat cgtcacgttg gatcccccgt aacaacacgc
    34801 ctacgttatc cccagcttcc ccgtaatcta acgttttacg gaacatttct acacctgtta
    34861 caactgcttt ttgtgtttca ggtttgatcc ctacgatctc tacctcatca ccgacacgaa
    34921 cagcaccacg atcaatacga cctgaggcaa cagttcctcg acctgtaatt gagaagacgt
    34981 cttccactgg caatagtaat ggtttatctg tatcacgttc tggtgttggg atatattcat
    35041 ctactgtatc catcaattcc ataatagcag cttcagcatc tggatcgcct tgcaatgctt
    35101 ttaatgcgga acctttgatc acaggagtgt catcgcctgg gaaaccatat tcgctcaata
    35161 actcgcgaac ttccatttct accaaatcga tcaattcttc atcatcgact aaatcaactt
    35221 tgttcaagaa aacaatcagg tattttacac caacttggcg tgacaataaa atgtgttcac
    35281 gtgtttgagg catcggaccg tcagttgcag aaacaactaa gattgcacca tccatttgtg
    35341 ctgcccctgt aatcatgttt ttcacatagt ccgcgtgtcc tggtgcatca atatgcgcgt
    35401 agtggcgttt ttctgtttca tattctacgt gtgcggtatt gatcgtaatc ccacgttcac
    35461 gttcttctgg agctgcatca atactagcat agtcttgagg atttgctagg ccttttttgc
    35521 ctaatactgt agtgatcgca gcagttaaag tagttttccc atggtcaacg tgtccaatcg
    35581 taccaatgtt aacgtgtggt ttacttctgt cataatgttc ttttgccata atttacaaac
    35641 ctcctaaata atatagatca ctgaaaaatt tcagctctca cctttttatt atagtctttt
    35701 tttgactaaa tcaaaaagaa tacgtccgac ttactttttg taagattcga actaagctta
    35761 ttatacgtca atattggtca aagtcaacta agagcactcg tctgtcttat acgcgaaaaa
    35821 agtacctttt ataaataaaa aaatgtgttt tttgagaaaa acttcaagat agtccttaac
    35881 tttcttttga agcaataaga acaaaatgag gaaaagttta aaattcagct gttgccaaca
    35941 actttcaata gacgaaatct tctatttcgt taataataag gaaagaggtg aagtacatga
    36001 aaaaattaat tggcgtactt gtcgttttag gcatatttct cggcggaagt tttgcagctt
    36061 atcattattt ttacggcggc gaagcttatt atacaaaaat cacgacgaat ggcgaaatgt
    36121 cagctaccca agcagataac ggagagaaat tcacgactta tacctacaag caagcggctt
    36181 ataataaaga tggtgaaaaa aaacaggtga cgcttcgcga agaaagagaa catccattaa
    36241 agatgaatgc gtatcttaaa ctcaaagtca atcctcgtaa aggtgtatta agctgggaag
    36301 aaataaaggc ttctgaagtg cctaaaaatg cggcagaaaa aatcgataat tagtaaatgg
    36361 tcttaaaatt ttattagata aaaagaggct gggacagaag cgtttaactc caagaaataa
    36421 gaaggagttg cttctgcttc cgccgtttat acgtgtttag agcgtgagac aaaagtgttc
    36481 tttacttttg tctcacgctc tttttttgtt atattcgtct tttccgatcc ttctcttgac
    36541 acaattcatt taactgatca ctggtacttg aacacctaat attctagtca tttttataaa
    36601 cgattcaata cttcatccac atttttgatc atcacggata tcgtaccatc cggattattc
    36661 acaaattcaa tcaaatctgg gttgcgatat acatctactg gtacgatcag ttcgatcccg
    36721 tttgatagct tgaatttttg ttttccaaat tttttctcag aaatttcttg tacttctttt
    36781 acaggaggtg cttctgggac aaatccttgc tcttgtactt cttctttaaa agccattttt
    36841 gccgtgatgt tttccttgaa gactttttcc gcaatcatct catgatccaa ccgacctttt
    36901 tcttctatcg tatcatagac agcttctttc aaatcagcca tgatatcaaa ttcttctgtc
    36961 tcaaattttt ttccaagatg cttggctact ttttggatca cttttacatt ttcttctaaa
    37021 gaaggtgcag gaacactttc gatcactctt ccagaaaaat aaagctcttt tttgccagaa
    37081 aactcatatt ttttttcaat taattcgtag gtccaatcag tcaaattcac agcgaatgct
    37141 tcatctgctt tttgtgtttt cgcccctaga attgctcgat tcaaaatcaa gcggttgtcg
    37201 atccctgctt cgtctgcttc aacaaagtga gtgtaagcct cacgataatt gactttcaat
    37261 aaagataagt acatcactgt atctaattca tacaagacaa caaatacatc tgcactaggt
    37321 gcttcttcac tttcttggta gatatcgaac caccgctgaa cgattgcttc acttgcttcc
    37381 acaaaatttt cttgagcgat tttaagtgat tcaacgatca tgctttcttc tgctagttgt
    37441 ccagtttttg tttgagcaga agagattttt tggatcttct tttgaagaaa atcacgaata
    37501 tattcttttg tcagatccag ctctttttgt gaaaagactg gagaaccagt ttctctgtca
    37561 ataatatgca gaattgcttt ttttaaatag atatccattt tctcattccc ttctgtctta
    37621 gtttacggaa aaaaaatcaa aaataccaga atcaaaatca ttttctttta aacaaaaatt
    37681 tcaagagtag aaacaaaatg gattcttttt ttcgaaaaat gcgctacact tatagttgaa
    37741 cgaataaaaa aggagctgaa agtatgaatt cattaacaag cacttatcgt ctatcaaatg
    37801 gttacgaaat cccggtagta ggattcggca catggcaaac acctgatggg gatgtcgctg
    37861 tttcctctgt taaagaagcg ctggctgcag gttatcgcca tatcgatact gcccaaggat
    37921 acaagaatga agaaagcgtc ggccaagcga ttaaggaaag tggaattcct agagaagaga
    37981 tattcttgac aacaaaatta tggaatgcaa accacagcta tgaacttgtg atgtcttctt
    38041 ttgaagaatc attgaagaag ctccaaacag attatttaga tctgtttttg atccactggc
    38101 caaaccctgt tgcttttcgt gataattggg aacaagcaaa tgcagataca tggcgagcat
    38161 ttgaagaact gtatgaagca ggtaaaatca aagcaatcgg tgtgagcaat ttcttacccc
    38221 accatctaga tacactagca aaaacagcaa aaattatgcc gatggtcaat caagttttcc
    38281 ttgcaccagg cgaattacag acaactgtag ttgagtatgc aaaaaaacat gatatgatcc
    38341 tcgaagcata tagtccatta ggcactggta aaatcttcga tgtgcctgaa atgaaacaaa
    38401 tcgctgaagc acatgacaag acgattgcac aagttgcttt gcgttggtcg ctgcaacacg
    38461 aattccttcc tcttcctaag tcagtgacac caagcagaat caaagaaaat actgaattat
    38521 ttgattttga attaacagaa gaagaaatga aacaaatcga tcagttagat ggtgtagtcg
    38581 gcaaagcaaa agacccagat actacccaat tttaagtcga aaggtgattt tatggatcca
    38641 atcgaacgct tgaattctct ctcggaagaa gttacccaga cttttcattc cgattttgtc
    38701 tttttgatcg atgcagagaa aatccaacat tttcctgcaa gaaactggac acatgatcaa
    38761 atcatcgaag aactgaaaaa acggttcgat cattcgctaa tggtcaaacc ctggcacgaa
    38821 catgaagtca tttattcacc tgaactacct gtttttgcct tgataccgaa aaaatagaaa
    38881 gaatggaacg gattatgtat atatacataa tccgttccat tttttatttt tctttcaaaa
    38941 aacgggaaaa tacgcaaatt tttctgttgt aatttgcgta tacgcaagtt tttttgcatt
    39001 actccttttc atttggctgt ttttttctta taatcgaaag ggtatgagcg aaggagagaa
    39061 catatgaaga aaaaacagaa acaaaaatta ttaaatcaat tccgtccttc attggatggt
    39121 gtaagaggac aattattccg ttctctagaa gaagagagct tgcgacgtta tggtttgccg
    39181 ttacaagtca tgcttgatcc caaaaaccgt caaatcttaa cgatcggatt agctgggaaa
    39241 acaaatgaag atacacggat caacgtgcca atcgatgaca acttcaatac tgtattaaag
    39301 agaattcgtt caggagaaaa cgggattttc gaacgattcc gtgacaatct tcttattgaa
    39361 atcgtgtctt actggaatga tcaacgattg aaaaacgatg aaccaactgc gcaagctgtt
    39421 gcgacaccag ttacagaaga aacagtcagt gtgccagaag aaaaaacgga aaaaccaaaa
    39481 gcggacacaa ctgaaaatac acgctcaact gatacgaatg ccgctttaag ttttgctgat
    39541 ttttcaaaag ccgttgctga gtatcctaaa ttttacacag aacaaaatga acatgaagta
    39601 gttattaatg aaaaaaatgc tgatgaacct cgtaaattag caactatttc tatgactact
    39661 gaaaatgagt tcgttatcga aaaagcactc gaacggaaat acaaagtcaa attgactttg
    39721 attcctttga tcgaacaatt tgcagcgaca gcgattactg atcgataaaa attctatttg
    39781 tcataaaagg ctgggattta aaatcccagc ctttttagtc atataataat ttctacagca
    39841 agtaaaaaga aattccttct aacatcaggc tcaaatatca gcttgacctg tccaacaaat
    39901 cacctatgat cctacaatgt taggcgactt ctcttctacc tgaagatatc ttggagttgc
    39961 ctgatttctt aagatgccta accttaacta taaaaaattc taataataaa catattttct
    40021 gatagagaaa aaag
//
LOCUS       DAZUJR010000013        39911 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.013, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000013 DAZUJR010000000
VERSION     DAZUJR010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39911)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39911)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39911
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.013"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            128..997
                     /locus_tag="ACG804_000667"
     CDS             128..997
                     /locus_tag="ACG804_000667"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HFS4831618.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            1162..2433
                     /locus_tag="ACG804_000668"
     CDS             1162..2433
                     /locus_tag="ACG804_000668"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFS4831619.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            2430..3725
                     /gene="rho"
                     /locus_tag="ACG804_000669"
     CDS             2430..3725
                     /gene="rho"
                     /locus_tag="ACG804_000669"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008186 - ATP-dependent activity, acting
                     on RNA [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HFS4831620.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            3824..4087
                     /locus_tag="ACG804_000670"
     CDS             3824..4087
                     /locus_tag="ACG804_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HFS4831621.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            4532..4981
                     /locus_tag="ACG804_000671"
     CDS             4532..4981
                     /locus_tag="ACG804_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFS4831622.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            5038..6456
                     /locus_tag="ACG804_000672"
     CDS             5038..6456
                     /locus_tag="ACG804_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HFS4831623.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            6456..7316
                     /locus_tag="ACG804_000673"
     CDS             6456..7316
                     /locus_tag="ACG804_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HFS4831624.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            7490..8263
                     /locus_tag="ACG804_000674"
     CDS             7490..8263
                     /locus_tag="ACG804_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFS4831625.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            8410..8775
                     /locus_tag="ACG804_000675"
     CDS             8410..8775
                     /locus_tag="ACG804_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HFS4831626.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(8923..10131)
                     /locus_tag="ACG804_000676"
     CDS             complement(8923..10131)
                     /locus_tag="ACG804_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4831627.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(10150..10428)
                     /locus_tag="ACG804_000677"
     CDS             complement(10150..10428)
                     /locus_tag="ACG804_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831628.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            10621..11277
                     /locus_tag="ACG804_000678"
     CDS             10621..11277
                     /locus_tag="ACG804_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFS4831629.1"
                     /translation="MDSRVLKEYLDKNDFPIIRKGYHKYLTFEGMEDSHTYILKEGTV
                     KASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESEYAEFYRINRVRFW
                     QNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLYELYDLFGVRTEEG
                     MLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIVILNMDLLEDNIIF
                     "
     gene            complement(11719..12516)
                     /locus_tag="ACG804_000679"
     CDS             complement(11719..12516)
                     /locus_tag="ACG804_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HFS4831630.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(12513..13697)
                     /locus_tag="ACG804_000680"
     CDS             complement(12513..13697)
                     /locus_tag="ACG804_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HFS4831631.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(13722..14969)
                     /locus_tag="ACG804_000681"
     CDS             complement(13722..14969)
                     /locus_tag="ACG804_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFS4831632.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            15184..16929
                     /gene="dnaX"
                     /locus_tag="ACG804_000682"
     CDS             15184..16929
                     /gene="dnaX"
                     /locus_tag="ACG804_000682"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HFS4831633.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            16949..17263
                     /locus_tag="ACG804_000683"
     CDS             16949..17263
                     /locus_tag="ACG804_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HFS4831634.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            17288..17884
                     /gene="recR"
                     /locus_tag="ACG804_000684"
     CDS             17288..17884
                     /gene="recR"
                     /locus_tag="ACG804_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HFS4831635.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            17948..18592
                     /gene="tmk"
                     /locus_tag="ACG804_000685"
     CDS             17948..18592
                     /gene="tmk"
                     /locus_tag="ACG804_000685"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HFS4831636.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            18607..18936
                     /locus_tag="ACG804_000686"
     CDS             18607..18936
                     /locus_tag="ACG804_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HFS4831637.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            18950..19888
                     /gene="holB"
                     /locus_tag="ACG804_000687"
     CDS             18950..19888
                     /gene="holB"
                     /locus_tag="ACG804_000687"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HFS4831638.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            19924..20748
                     /locus_tag="ACG804_000688"
     CDS             19924..20748
                     /locus_tag="ACG804_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HFS4831639.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            20741..21088
                     /locus_tag="ACG804_000689"
     CDS             20741..21088
                     /locus_tag="ACG804_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HFS4831640.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            21157..22029
                     /gene="rsmI"
                     /locus_tag="ACG804_000690"
     CDS             21157..22029
                     /gene="rsmI"
                     /locus_tag="ACG804_000690"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HFS4831641.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            22138..23259
                     /gene="dinB"
                     /locus_tag="ACG804_000691"
     CDS             22138..23259
                     /gene="dinB"
                     /locus_tag="ACG804_000691"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HFS4831642.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(23313..23915)
                     /gene="nrdG"
                     /locus_tag="ACG804_000692"
     CDS             complement(23313..23915)
                     /gene="nrdG"
                     /locus_tag="ACG804_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HFS4831643.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(24230..26419)
                     /gene="nrdD"
                     /locus_tag="ACG804_000693"
     CDS             complement(24230..26419)
                     /gene="nrdD"
                     /locus_tag="ACG804_000693"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HFS4831644.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            26745..27512
                     /locus_tag="ACG804_000694"
     CDS             26745..27512
                     /locus_tag="ACG804_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4831645.1"
                     /translation="MEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGEFVGIMGPSG
                     AGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQEFNLIDTLN
                     AKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQRIAAARALV
                     VQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTASYCDRILFIK
                     DGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            27502..29544
                     /locus_tag="ACG804_000695"
     CDS             27502..29544
                     /locus_tag="ACG804_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4831646.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            29825..29974
                     /locus_tag="ACG804_000696"
     CDS             29825..29974
                     /locus_tag="ACG804_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HFS4831647.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            29985..31499
                     /gene="dltA"
                     /locus_tag="ACG804_000697"
     CDS             29985..31499
                     /gene="dltA"
                     /locus_tag="ACG804_000697"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HFS4831648.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            31496..32701
                     /gene="dltB"
                     /locus_tag="ACG804_000698"
     CDS             31496..32701
                     /gene="dltB"
                     /locus_tag="ACG804_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HFS4831649.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            32746..32979
                     /gene="dltC"
                     /locus_tag="ACG804_000699"
     CDS             32746..32979
                     /gene="dltC"
                     /locus_tag="ACG804_000699"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HFS4831650.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWCTPNKIIQQATALKG"
     gene            32982..34250
                     /gene="dltD"
                     /locus_tag="ACG804_000700"
     CDS             32982..34250
                     /gene="dltD"
                     /locus_tag="ACG804_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HFS4831651.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            34391..35473
                     /locus_tag="ACG804_000701"
     CDS             34391..35473
                     /locus_tag="ACG804_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HFS4831652.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            35473..36276
                     /locus_tag="ACG804_000702"
     CDS             35473..36276
                     /locus_tag="ACG804_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HFS4831653.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            36346..37086
                     /locus_tag="ACG804_000703"
     CDS             36346..37086
                     /locus_tag="ACG804_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFS4831654.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            37097..38101
                     /locus_tag="ACG804_000704"
     CDS             37097..38101
                     /locus_tag="ACG804_000704"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017118 - lipoyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HFS4831655.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(38146..39909)
                     /locus_tag="ACG804_000705"
     CDS             complement(38146..39909)
                     /locus_tag="ACG804_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831656.1"
                     /translation="MLFLTGIAYFFYFIFSPADSNQMKEIKDSWVFYTKDDPDFKFDS
                     KYTRTIPTVDKDETFIMETTLEKPLDEANLLIKGNHQWITVYLGEKILYQRKDYQEES
                     NPGLSLAVIDLPANYIGKKLTLTVSSPYQNYAGLPPKVYLGTTGPLISFIYSQSVPQV
                     LTMIIAVFIAIGTFFYTIYLMYKQKRLEYSLILLSCFALALGFEAVSEDILSGILFEP
                     FVHSFLSHLFIILTSAFIICYYWSRMFYYKKWYGIFCTFQLLIFIGVLLYATFTPAEL
                     PELMPIANIASVISTLVTSLACIGEAYKNNRFYVACTPWIVLVAIIHCLIYIQTALGI
                     YQTTINWSTILYIIILIVIISYNLIDHILNTDKDRRQVDFLKIKNDLLEQHYEQLRQH
                     IQEVNTLRLEFVQEMENLQDLMHTDQTKAKNYVEKILEEAKNFEMLCSFCNHQVTNLI
                     LARYQKLAAKRNIQITFQADLPEELPINDDDLAQLLIHALEHSFRETHAIENPLYRKI
                     YLSIHEQEEHFVICCEHSAHYDTNLFSRGITEELDDQERFDLMMMKDVADRYTGTLTQ
                     EKDTFIDRITVQLSRNYPNPV"
BASE COUNT        12799 a         7024 c         8282 g        11806 t
ORIGIN      
        1 acttcttgaa aattttcatt ttcattgatt ttagtagaaa actaccgaaa tgtttggtaa
       61 aatagggtcg ttggttaaga attgtcttaa caaatttagt tttacaaaac ttaggaggaa
      121 ttttattatg ccagtagtat caggagctga atttttaaaa gctgctcgta aaggcggtta
      181 cgctgtcggc ggattcaaca caaacaactt ggaatggact caagcaatcc ttgaagcggc
      241 tgaagcaaaa caagcaccag tacttatcca aacatcaatg ggtgcagcta aatacatggg
      301 tggttacaaa atctgtaaag atttaatcac tgatttagtt gaagcaatga acatcactgt
      361 tccagttgct atccacttag accatggtga ttacgaagct gctttggaat gtatcgaatt
      421 aggctatact tcagtaatgt tcgatggttc acatctacca tttgaagaaa acttgaaatt
      481 agctaaagac gttgttgaaa aagcacatgc aaaaggtatc tcagttgaat gtgaagttgg
      541 ttcaatcggc ggagaagaag acggaatcat cggtaacggc gaattagctg atattgaaga
      601 atgcaaacaa atggttgcta caggtatcga ctacttagct tgcggtatcg gtaacatcca
      661 tggtcaatat ccagaaaact ggaaaggatt agcttttgac cacttacaag caattgctga
      721 tgctgtaggt ccagacatgc ctttagtatt acatggcgga tcaggtattc ctcaagatca
      781 aatcgaaaaa gctatctcaa tgggtatctc aaaagtaaat gttaacactg aattccaatt
      841 atcatttgct gcagctactc gtaaatatat cgaagctggt aaagataaag aaggtaaagg
      901 attcgaccct cgtaaattat tagctccagg taaagcagca atcgttgaag atgctaaatc
      961 tcatatcgac tggttcggtt cagctaacaa agcgtaagca tccacataac agatacgata
     1021 tataggaatg gagaacgact tttgaagtcg ctctccattc ttttttactt aaaacggcag
     1081 accatgctcg tttctttttt ttatctatga taaaatacaa gcatatccat gaaaaaagat
     1141 taataaacaa ggtggaaaca gatgaaaaaa atcgtaatca aaggaaaccg acctttagct
     1201 ggtgaagtaa cgatcagcgg tgcaaaaaat agtgcagtcg cattgattcc agctgcaatc
     1261 ttagctgatt ccccagtgat cttggaaggt gtgccggaca tacaagatgt tcattcatta
     1321 attgaaattt tagagatcat gggcgcaact gtccattttt ccaacaacat actagaaatc
     1381 gatcctcgag aagtcgtatc gattccgatg ccgcacggaa aaatcaatag tttgcgtgct
     1441 tcttattatt ttatgggaac actgcttggt aaatttggcg aagcggtagt aggcctgcca
     1501 ggtggctgtt atttaggccc tagaccgatt gacctacacg tcaaaggatt tgaagctcta
     1561 ggtgctgaag tgacaaatga acatggtgcc atgtatttac ggacagaaaa taaaggattg
     1621 cgtggcaatc ggattttcat ggacgtggtt tcagtcggag caacgatcaa tgtgatgtta
     1681 gctgctgtaa aagcaaaagg acagacagta attgaaaacg ctgcacgaga accggaaatc
     1741 atagatgtgg caactttact gaataatatg ggggcaaaag ttcgaggagc gggtacagat
     1801 gtgatccgta tcgaaggagt cgaaacatta catggctgtc ggcatttcat gattcctgac
     1861 cgcatcgaag caggaaccta tctagcatta gcagctgcag taggaaatgg tatcaaagtg
     1921 aaaaatgtga tctttgaaca tttggaaagc tttatagcaa aattgcagga aattggtgtc
     1981 catatgaaaa tcagcgaaga tgaaatcgaa gtttacccct cgaaagaatt aaaacccgca
     2041 aacatcatga cctatcctta tccaggattt gccacagatc tgcagcagcc acttactgcg
     2101 ttactattga tgactacagg cacttcagaa atcatcgata cgatctatgc gaaacgtgtg
     2161 aaccatgtgc cggaactagc acgaatgggc gctgatatta ccgtggaagg aaatatgatc
     2221 atcgtgaatg gtccaaataa acttcacggc acagaagtcg tggcttctga tcttcgggca
     2281 ggtgcttgtt tagtgattgc tggactattg gcagaaggga caacgacgat ttacaatgta
     2341 gattatatct tacgcggtta tgatcatatt atcgagaaac taacagcctt aggggcatca
     2401 attgaaatga tagaggaagt gggagctgaa tgagcgatta tttgacaatg gcagaactag
     2461 agaacaaaac gttaaaagaa gtttatagtt atgccaaaga atttaaaatt ccttattaca
     2521 gtaagatgaa taaaaaggaa ttatctctag ctgtgattcg tgcacaagca gagaaacaag
     2581 gattttatta tatggaagga atattggata tcgttggtca agatggttac ggttttttac
     2641 ggccaatcaa ttatggacca agtgcagaag atatctatat ttctgcctca caaatcagac
     2701 gattcagttt gagaaatggg gacaaagtgg caggaaaagc ccgtccacct aaagaatcgg
     2761 aacgttatta tggtttgatg cacgtggaaa gcgttaatgg aaaagatccg gaagaagcaa
     2821 aagaacgtcc gcattttcca gccttaacac ctctttatcc gcaaagacag cttcaactgg
     2881 aaacaacacc gcaaagacta tctacccgaa tgatcgatat cttttctcca atcggttttg
     2941 gtcagcgtgg attgatcgtc gcaccgccaa aagcagggaa aacttctgta ttaaaagaaa
     3001 tcgcaaatgg tatcaccgaa aactatccgg aagtagaatt aatcgttcta ctgattgatg
     3061 aacgaccgga agaagtaacg gatctagaac gaagcgtgaa aggcgacgtg gtatcttcta
     3121 catttgatct gcagccgcaa aaccatactc gagtttctga attagtattg gaacgcgcaa
     3181 tgcgtttagt cgaagataaa cgagatgtcg ttatcttgat ggatagtatt actagacttg
     3241 ctcgggccta taacttagtc gttccaccaa gcggacgtac attgagtggc gggattgacc
     3301 cagccgcatt gtataaacct aagaaatttt tcggggcagc aagaaacatc gaagaaggtg
     3361 gcagtttgac gattttagcg accgctttag tcgatacagg aagccgtatg gatgacgtga
     3421 tctatgaaga attcaaagga actggaaatc tagaattaca actttcacgt gaattatctg
     3481 aacgtcggat cttcccagcc atcgatatca aaaaatcagg tacccgaaaa gaagaattat
     3541 tgatgccaag tgaagaatta gaagaaattt ggaaacttcg aaaaaatatg actggagatt
     3601 cattagaata tacggaacaa ctgatccgct ttttgcgtaa aacaaaaaac aatcagcaat
     3661 ttttcaaaga atttcaagat gtctcctttg gtaaaaaaaa tccgaccaga aatctgaaaa
     3721 gataattgca accttgactg aaacatgtta agatgttaat gttgtaaatc gacaaatcaa
     3781 ctctggttca gcaaatggag cagggcaaag gagcgaaaaa atcatgaaag aaaacatcca
     3841 tccagattac cacccagtag tattcatgga ttcaacaact ggtttcaaat tcttgtcagg
     3901 ttcaacaaaa acttcacaag aaacagttga atgggaagac ggtaatacat acccagtcat
     3961 ccgtgtcgaa gtaacttctg actcacatcc attctacact ggacgtcaaa aattcacaca
     4021 agcagacgga cgtgtggacc gtttcaacaa aaaatacggt ctcaaagacg caaacgctgc
     4081 ggaataataa aaacgctgat aactcaacgt ttagcagact atctgatagg gatagtctgt
     4141 ttttttatgt tttttgccaa tttaaaactt cgtttgatgc tgaaaaagtc gtaggatcat
     4201 aatgcacaaa acaatgaaaa actagtatat agttttaatt atccacttga taaaaacacc
     4261 ttatattaac gaaatgaaga ggggttattt cgaagtaaaa aaccatttac ctaaaattag
     4321 aagctaagct ttcctttcaa ggaaggcttt ttgttttgtt atagacttgc gattgtttgt
     4381 gagctagatc gttcatttta atgacttata cacgcggatg atgggtcttt ttcctctgtt
     4441 cattcataat attgaacggt acagctagcg atgctatact gacctcagtt ccaagaaaac
     4501 gttaacattt tttgtggggg agaggttttt tatgaggttt gatcaattga tcgcagaaga
     4561 actgattgtt ttcgatccat cgatagattc aaaaggatca ttatttgagc gaatagggga
     4621 tgtgttgaaa aaaacaaata aggtaagaaa tgttcaaaaa gtcgttaagg cactattcaa
     4681 acgagaggag gagatctcca caggaataga agatggattt gggattcccc atgcaaaaag
     4741 caaatatgtg acaaaaccag cactgtgttt ttttcataca gccaaattaa cggactatag
     4801 cgggatagat gaaatgccaa ttgaatatat ttttgccatc gtagttcctg aaaaatcagc
     4861 agatatgcat ctagagattc tcagcacact ctccagacga ttgatgaatg cagattttag
     4921 aaagggaata aaagaagcca ctacgccagc agatatcatc agacagatta gtcaagaatg
     4981 aaaatagtag agtctttgtc cgagtatcga tagtgaagaa aaaggaggaa aataatcatg
     5041 aaaatcgttg gtgtaactgc ttgcccgact ggaattgctc atacttatat gtcggcagaa
     5101 aaattagaag taacagcaag aaatctaaac catcaagcaa aattcgaaac acaaggtgta
     5161 aaaacagaaa atcagttatc tgaacaagaa atcaaagagg cagatgcaat cattcttgca
     5221 gtagataaag aaatcgaatt ggaccgattt gccgggaaaa aagtaaagcg tgtctctaca
     5281 agccgagcaa tcaaagaacc gcaagtagta atagacgaag cattgagaga tattggcgta
     5341 ttcgttgtgt ctaatgaaaa agaaccagct gcaaatgaga aaaagccgac aatctataat
     5401 catttcatga atggtgtgaa ttacatgctt ccatttgtga tcgcaggcgg aatcatcatc
     5461 gcactgagtt ttgcctttgg gattacagcg gctgatccca actcagcaga ctataatgtg
     5521 ttagcagctg cattttcaag gatcggagga gatacagcgt ttgccatgat ggttcctgcg
     5581 ttaggcgcgg ggattgctac atcgattgct ggaaaagcag gttttgcccc aggaattgtt
     5641 gccggattac tggcctctac aggtggttca ggttttcttg gcggaatgat tggtggcgtg
     5701 ctagcagggt atatctgtga ttttctggca aataaaatta gcgtaaaaaa agaattttct
     5761 gctatttatc agctgattgt cgtccccttt ttatcgatct taattattgg gcttttgatg
     5821 gtatttgtga ttgaacaacc gatcacatgg gtgttggatg ctttgacaaa ttggctgaat
     5881 agcttgggaa atacatccgg gctattgttc ggattactta tcgggatcat gatggcagct
     5941 gatatgggtg ggccgatcaa taaatcgact tcgactttct cgatcggttt gatgtcagct
     6001 ggagtaaatg caccgattgc tgcttgtatg gctgcaggaa tgacacctcc cctaggtatt
     6061 gctttagcca ctttattatt caaacataaa tttaccaaag aagaacggac ttcaggtcaa
     6121 tcatgctgga ttttaggcgc ttcgtatatt acagaaggtg ctataccgtt tgcggtatct
     6181 gacccgatcc gcgtgatacc tagtttgatg acaggttcag cagtcgctgc agggatttcc
     6241 atggcagtag gagttacttc aatggcacct catggaggga tttgggtgat gctaattcca
     6301 aatgttatga acaatttacc tatgtatgtc ttggcaattg catcaggtac agtcactaca
     6361 gcctttatgc ttggactatt gaaaaaaaca gtgaaagaga aaaaacaaga caagtggacg
     6421 aaaaatgaaa atctaacaaa tgaggtggaa gcgtaatgtt atatacaatg aaagagttat
     6481 tgaaagtggc taaagagaat caatttgcag taccagcctt caatatttgc agctatgata
     6541 tgatgaaagc aatcatcgaa gaagcagaga gattagaagc accagtaatc ttagaaattc
     6601 atcctgatga aatcgcctat ttaagtgatg agtttgttgc ggcagtaaga gcctatgctt
     6661 atacaagtaa actgccgatc gttatccact tggatcatgg cggtacgata gaagatgtct
     6721 tacgggcgat tcgaaacggc tattcttccg tgatgatcga tgcgtctttg aaatcattcg
     6781 acgacaatgt acagattacg aaaaaagtgg ttgcgttagc tcatgcggta aatgtctcag
     6841 tggaggctga gcttggaacg attgggaata atggttctgc tgaaggaggt gctgaaacaa
     6901 tcatttatac agatcctgat caagcgaaga tttttgtgaa agaaacagga atcgatacac
     6961 ttgctgtagc aattggaaca gcgcatggct tgtatccgaa aaacagaact ccaaaattaa
     7021 atatcgactt actgaaagaa ttgaaccaac aaatcgatct tccatttgtt ttacatggcg
     7081 gttcaggtaa tccggacgca gaagtcagcg aagcagtaaa atacggagtt gccaaagtga
     7141 atttgagctc agatcttaaa agcgtctttt tcaatgcttt gagagaaata ttgagtgaaa
     7201 atccatcgat gtacgagccg aatgcaattt atccagcagc taataaaaag gtacaagaag
     7261 tggtcaaaca taaaatggaa attttgaaca cagtaggcaa ggctagttta tactaaaaat
     7321 aaaaatgtgt ggtcaagagg gtatgacaat agtcttgtca taccctctta accacacacg
     7381 atgttcagaa gtagtttttt cgaaaaattt cttcttattt ctcgaagcca atcacttctg
     7441 tcacaacctc ttttttcctg ttactatata aagtaaatgg ggtgatttta tgttgaatga
     7501 agtggagaat agacagcagg agattgtgaa ttatctaaaa aacaaccaat ttgcaagagt
     7561 caccgatttg atcgagttag taaattatag cgaagccacg attaaacgtg accttgtttt
     7621 tctggaaaaa agtggattga tccgtagagt tcgcggtggc gccatgctta ttgacaatcg
     7681 aaaaattgac gtgccttacc tgatgaagat caccaaatta gaagaagaaa cagaaaaacg
     7741 taagattgca gatacagctt cttctttgat tcgagatgat atggtcttat tcttggattc
     7801 cagtacaacc tctttacact tagtcagaaa cctagcaaga tttgatggtt tgcagatcat
     7861 tacgaatggc atcgtcacag ctgctatgtt gagtgaatat acaacggcaa aagtatctgt
     7921 attgggaggg gcaattgttc cgaaacgagc aacaatcaac ggttcaaaag cctataacga
     7981 tgcattgtca tattatgcgg atttagcgat aatgagttgt cgcgggctag atttcagcca
     8041 aggagtaaca gaaactcatg aaggagaggc aatggtcaaa aaagctttta gaaaacaatc
     8101 agaccggctt gccgttttag ttacacagca aaaaattgca cataaattca tgcatcaagc
     8161 cattgctttt catgaaatcg attatctggt gacaagtaaa gaactgacaa aagaacagta
     8221 tgcgaaagta aaggaacacc atatcgaatg tctgtacgga taaattatta cgtgaatgtt
     8281 ctaagtggct tcctcatttt tagataggac cttatctttg ctcgcttctc tcagccgatg
     8341 gtataataat gaaaaggtta tcttgttaga taatcttact tttttatcca ggagaaagga
     8401 gtgcagaaaa tgaaacatgt gaaggcgttg gtagtgaagg caatcatgat ctgggcgatt
     8461 ctgtgggtcg tgctgacagg tttatacggt gttagcttta tggattcaac gattgttggg
     8521 gtaattattg tagtcatgat ctatgtgcta ggggatctgt tgatcttacg taaagtaggg
     8581 aacatcgcag cgacgatcgc agatgctggt tcagctgcag ttatcttgtg gctctatcta
     8641 tattttatga atgatacagt cgatatttgg atgaaagtat tgattcctgc tctattgatc
     8701 ggtgtggcag aatggttctt ccacaagtgg ttgctaagtc aaggcatcgt accagatgaa
     8761 cggaaaatgg aataaatcaa cagttaaact attcttatcg ataaatgaaa gctttaaaaa
     8821 taaatagatg tttaattaag aataatcata aactattttt actcaaaaaa ccgctcagat
     8881 tattttcaga tctgaacggt tttttttatc tattcatcaa gatcaaattt catttttcaa
     8941 tgattcaatc aattcgccct ctgcttcatg actatgtttt cggccattaa caagatagag
     9001 tgctgtacat atcaatggaa tgactccggc aatcacatac aatcctctaa atgaagtaag
     9061 agattttagc atccccatca aataaggacc aacgcctaag cctaggtcta aaccaataaa
     9121 gtaggtagat aaagcaatac tgattcgatg ttcgcggacg atttttaaac aaacagcctg
     9181 tccatttgac ataaacgtac cataacctag gccgactaat gctccagaga taagcaatgt
     9241 cacactattc gtcgttacac tcagtaaaaa taatcctgct gttaagaata aatagctagg
     9301 atacatcacg tattgttctc ctttgacatc gaaaatcctt ccagtcaatg gacgtgtaaa
     9361 tgtgatgacc aaagcatata cgacgaagaa aaatgaccca gcagcaacta agtggattac
     9421 ttttgtataa gaagataaaa atgataaaac acttgaataa gaaagaccca tcaaaaaggc
     9481 aattcctgta atgaaaagtg ctttcttttc aataaaacta ttgatattcc atgagcgaag
     9541 agatattttt tgttcttcag ataatggaat attttttaca ggaaagacaa ggcaggcaat
     9601 cgtaacaaag aagaccagta caattgaaaa ccagataatg aaacgaaaat cagtcatatt
     9661 cagcaaaatc attcctaaaa atggcccaac agcggcagct aaactagtac ttaatccata
     9721 ataattgatg ccttcccctt ttttagatgc agggatatat gcagtaacga tagcatttgt
     9781 agctgtagaa actgtaccgt agccgaatcc attcaagaat cgaactaaat acaatgcccc
     9841 gatagttggc gtataaagat atgctaatgt tgaaaggaga tagaagatcg cgccgcctct
     9901 taaggtaaac ttccgaccaa atagttctaa ctgtttcccc atgaataagc gtgccagcaa
     9961 tgttccgatg atatagatcc cagaagcaaa acctgcttgg ctcaagctgg cgtgtaaggt
    10021 gtcttgcgca atgactgcca tgatgaccat caacagataa taaatcaggt agacaataaa
    10081 attgatcaat gtgattccaa taaaatattt attaaataat ttcttttcca tgtatgttat
    10141 acattcccct taagctgaat atgcttttaa tttttgtatt tgaacttcta catcgtgata
    10201 attggatgga tagcgatcaa caagttggcg aataaataaa tctcttgtag acataaacag
    10261 atttaaaaat tcttcgcatt cgtttgttgg attctcatcc actgctttga tcaattcgat
    10321 cgagttttga tacgcatcat ttaaaaagac taaagaagct ttcatatcaa atcttgtttg
    10381 atatgctgtt tctaatcgat taatgattgt gttcatccag taattcatgt tttttccctc
    10441 tattcttaaa aaattttact tctgcagtat aacgaataaa aaaaaggaaa aaaatcgcat
    10501 aagtgatgga aaaaggtact taacaaatgt taatatcatt agtaaaatac ctttggactt
    10561 taaaaagttt taaagtactg tatgatcttt ttagatgaaa gtttggatgg gggagcatca
    10621 ttggatagta gagtcttaaa ggaatatttg gataaaaatg attttccgat tatacgcaaa
    10681 ggatatcata aatatttgac attcgaaggg atggaagatt cccatacgta tatcttgaaa
    10741 gagggaacgg taaaagcaag tgttatttca aatgatggga gagaatttaa ccttcgctat
    10801 atcaaagatc ttgaaatcgt ctctctttta aaagacgaat attcacaatt catcgattcg
    10861 ccgtataata ttcgagttga atcagaatat gcagagtttt atcgaatcaa tcgtgtgcgc
    10921 ttttggcaaa atatcaacca agacccaaag ctacaacact atgtaaaaga gtattaccgc
    10981 tatcgtctgc tttattcgat gaaaaaaatg cagcaaatgc tattaaacgg aaagctggga
    11041 gctgtttgta cgcaacttta cgaattatat gatttattcg gtgtgcggac agaagaaggg
    11101 atgctgatcg atttttcgat cacgaatgaa gaaatcgcca aattttgtgg catctcaact
    11161 gctagcagtg taaacagaat tttaaaacaa ctgaaaaaag atggtattat caccgttaaa
    11221 gaccatcata tcgttatttt gaatatggac ttgttagaag acaatattat cttttgatga
    11281 acaaagaggt tgtgaaatca gcgttttgac ctgagtatta gagaaacaaa cggaaaaata
    11341 gttcctcata ttttgccgtt ttttgagcta ataccgaggg tcagctgatt gaacaccgtt
    11401 taccaagagg ttgtgagcct gccgtttaac tctgagtcac aaggaacaat ttcaaaaaac
    11461 agcttttcat gtttgatgaa tattgtgact tgtgaccgag gagttggtag gagaacaccg
    11521 tttaccaaga ggttgtgaaa aagctgttct gcatcaagta ataagaagag ccaagtaaaa
    11581 acagtctctt atgtttttaa cttggctgga cttatcaccg tagatgtaag cttttgaacg
    11641 ccgtttattt gcaacaaaag gggctgtgac acgatttttg tcacagccct ttttttgcga
    11701 acattcattt agcaattttt agaaacttct gccgccaccg ccaaaagtcc cgccaccgct
    11761 agaatgggta gtacttccgc caccgccgct tccaggaggt gggcttttgg ggattcttct
    11821 tgtcgtgaca aaagaatttg tcagacgatc ggttttttca gttaatttga tactggattt
    11881 ttctcggaat ggatatttgt agatgcctga tttcaattga taacgcgaaa cagtcacaaa
    11941 ataaaagaca agactaagga taagagccaa aacaacagca atgatgattt ctactgtcgt
    12001 caaaacctta tagcgtgtaa ttttgccagt ttcttcgtct acacgataat gtcctcctgg
    12061 aactccgtct tccacatatg ttgctgattt agacaggtaa gcttttgcag cattgtaata
    12121 ggcagcattt gtcatctgat cataaacatc atctaagatc gaatcgattc tgctatcagt
    12181 caaataatcg atcatattac cagaagtcga aatgtagatt tcacgctgtc ccatatctaa
    12241 tagcaatact gagccatttt gatcatttcc gactgcgtct cttaagtaat tatcagcaaa
    12301 gtctcttggt tcttctgaat tagatgtagt cgttacgatc aagactcgtc ctttgatttt
    12361 ttcattcagc ttttctgcct gttgttccaa agattggatt tgatctgttg tgaataaccc
    12421 agcctcatca tttaccgtag ctgtatctgc atgagtagcc accggccagc caacacttac
    12481 tagcaaaaga aagaataaaa aaaatttttt catcatatca agtaacctcc gatcagaaag
    12541 aggatcgcta gcccagcgaa aatcccaaga gcggtcagtc ccaatttttt ctggctgatc
    12601 ggcaggacac cgctgacctt tcctgtttgt ccattcattg cgtagtagta gactttttta
    12661 cttgagtcat tgcttcgata agtaacaagc cataccggca gtaatacgta attatttact
    12721 tcgtttgtga ttgaagcaga agttcgcaca ccggtcaatg ttgtatatcc atttgcggta
    12781 tcttttaaca gcttctctga atagtctttt aattcagatt gaatctgtga tttgattgcc
    12841 tcatattcga tatctctttt ttctgcttgg aacccggcta aatactggct tttaaaatca
    12901 attgctttat ctaacgggaa aggttgcacg ccttcgacca tcttttgttg cgtatttttt
    12961 gataaggcat tttttactag ttctttaaaa gaaagcttgc ctgctcttga aacagcaaat
    13021 tgcttcgttt ctgtgtattc gatgtcacct atccgccata tgcggataac tgtaccattc
    13081 gcctgcatgg caccatctac ttcagcatct gtagcccaat aagggaaata cacacctgtc
    13141 aacttatcga tttgatcctt attgaaaaaa gctttgggaa caaaccattt tttcttggtc
    13201 caagcgagaa atctgttgat tgcttcttct ttctcgacag caaaaggaag tactttattt
    13261 ggcaagaatt ctccgcttaa acgtcccgat agtacgacgg gattatggca gtagtaacaa
    13321 taagtcgcag cagttgtcgc atcagtcacg atctctgcac cacagttggg acaaagaaaa
    13381 agatctatcg ctgcggtatt atctgcagat tcgtccgctg tatctgaaaa accgcctgcc
    13441 tcgtcaaccg ctttgcgctc ggcttcattc atatcggcaa gctgttcttg ggctgtaaaa
    13501 gtaaaatctt cggtaggtga aggttcttct ttgctttctt cgccagccat acgcgcttct
    13561 ttttgctttt gctcatattg gctgacttct tcttctgtat agatattcag gcagtattcg
    13621 caatgaaatt tttggtcttt gggatcaaaa gtcaacggac cgccgcaatt aggacattta
    13681 tgtgtaagaa catccatcag ctgcacacct ttctaaataa attaattaac ggggattcct
    13741 ttaaacggtt taccacagtt tggacagaat ttagggatgc cgttggaaag atccacgatc
    13801 tcattgcatt cactgcatcg catttgtagc ttaggctgaa cgttttctac aggtttggca
    13861 gctccgcagt tggaacagaa ttttccggaa ttttctgtcc cgcaaactgg acatgtccaa
    13921 gtatccgcat ttccttgtgc agtttgttga ttttgttttt ctgcttgttg tttgatttgt
    13981 tcttggttat tttgagctgc ttgagaaaga taagaaccat ttgcattcat tcccatacct
    14041 acacccataa agccggtcat tgctcctgct tcattttttc cggctgcttc cataccacgt
    14101 gcaatggaac cttgcacgta gccttcacgt acgctaggat cacctagcat cgccccttcg
    14161 ttacgcatat tgatcagttt cacagaatca tcggtgtaag aaatgctggc tacagccaca
    14221 gaaacaatct ccatcccacg taattcacgc caagaatcat ccaatgcagt atccatgtat
    14281 ttgcttaatt ccaaactctt agatggtaca taagaaatcc gttgaccatc tgcagacatc
    14341 tgattgattg ctgattgtag cgctgttagg aattcagcta aatactgctc attgatatca
    14401 ttgatttcca cttgtgtttt gtttttaggg attgcgtttg tataaaataa aatcgggtca
    14461 acgacatgaa tagaataagt gccatgtgcc cgtaagaata attctgcgtt atagaaattg
    14521 tcaaagtagt tcaacggcgc gcttgtaccg aatttgattc cctttatttc ttggagattg
    14581 atataaaaaa cttgttgttt ctgcggtgtg acgccgccaa atttgaatcg gtcaaaagtt
    14641 tcagcaattg cttctttcag tgttccattg aacatggaag gagctgcgtc atttttaatg
    14701 gtgtaataac cttcctcagc ggtataatcg atgatttttc caccatcgac caaaagcatc
    14761 atcatgtttg gatagacatg gacgactgtt ccgtctgtta aaacatcttc tgttccttta
    14821 cgattggagc cacgtttgtc atctttgcgg actttgacac cttttgtcat gaccgttgta
    14881 tcactcatat tgtctggttc gatgacttct agccattgat ctgccagacc gccgccaacc
    14941 atacttgttg ctgctttgat aagacccata aaaaattcct cctctgattc agctagtgcc
    15001 aaacaattat tgtttattta ttataccata ggaagatgtg aaacttctcg gactagagac
    15061 ggaattgaaa tggaaaattg cgtattgttt aaatacctga aaaagccgag aaggatagta
    15121 gtttttttac ctaatatcac gtataataag agatagtgaa ttttttaaaa aagggggatc
    15181 cttatggcat atcaagcact ttatcgagtc tggcgttcgc agcgtttcga agacatcgtt
    15241 ggacaaaaag ctgtgacaca gacactaaaa aatgctattg tttcccacaa aacctcacat
    15301 gcctacttgt ttacaggacc cagaggaacc ggaaagacga gtgcagcaaa gattttcgca
    15361 aaagcaatca actgtccgaa cagtaaagac ggtgagccat gcaacgaatg cgaaatgtgt
    15421 cgatcaatta ctgctggtac gcaagaagat gtgatcgaaa tcgatgctgc cagcaataac
    15481 ggagtcgaag aaatccgatt tatccgtgat cgggcaaatt atgcgcctac aaaggcagcg
    15541 tacaaagtgt acattattga tgaggtacat atgctttcaa caggagcttt caatgccttg
    15601 ttgaaaacat tggaagagcc aaaagaaagt gtcatattca tcttagcaac gaccgaacct
    15661 cacaaaatac cagctacgat catttcacgg actcagcgat ttgattttaa acggatcaat
    15721 acggcagata ttgtcgaaca tcttgaattt atcttgaaag aatcgactat cagctatgaa
    15781 ccagctgcat tgaatgtgat tgcccgttct gcagaaggcg ggatgcggga tgcattgagt
    15841 attcttgatc aggcaatctc gtttagtgaa ggaacaatta ctttagatga tgccatgcaa
    15901 gtgacaggta gcttaactga cgaaatgatg gacagttact tgagtgcttg cgtgaaaaaa
    15961 gaagtaccag aagcattgga aacattgaac caaattctcg cagccggcaa agaatcacgt
    16021 cgctttctag aggatatgtt acaatactgc cgtgacttgc tgatgtatca gcaagcacct
    16081 aacctagttg aggaacaatc gagtacgatc agaagtacat ttacagaatt ggcacaaact
    16141 gtttcagcgg atcagctgtt ttcaatgata aagattttga gcgatactca aaatgaaatt
    16201 cgttttacca atagtgccgc tatttatttg gaagtcgcta cagtcaaact tgcacagcta
    16261 ccgtctgctt ctgttccttc agcagatgta gcatttgcag atgatcagat agtaaaacag
    16321 ctacaacaag agattaagga actaagaaac gaaatcaagg aactacgcag taatacagga
    16381 attgagaata caaaagtaca gccggtacag caaacaaatc ataaaaaaca gacaagtacc
    16441 tatcgtgtac cgacggaacg agtatataaa gttctgcggg aagcgacaag acagcatctg
    16501 aaccaagtaa aagaagtatg ggaagacttg ctgatgagtc tatctgtcac tcagcgagca
    16561 atgcttaaag caagcgaacc agttgcagct ggacctacag gactagtgat tgcgtttgat
    16621 tatgagattg tttgtcaaag agcagcaaat gacgaagaat tgcagctttc ggtacacaac
    16681 aacttaagcc gaatgatcaa agattatgcg cctgatcctg tttatattac aagagaaagc
    16741 tggccagaac ttcgaagaaa ttatttgacg caggcacaag aagagggaac agaaaactct
    16801 tttgcttctg aagactcaga aggagaaatc gagttgcttc ctcaagaaca agaagtacca
    16861 gaagaaacac ttgtagtaaa agcagaggaa ctgtttggct ccgaagctgt tacagtggta
    16921 gatgattaat aaaaaggagt agataattat gatgcgtgga atgggcaata tgcaaggcat
    16981 gatgaaacaa gtacaaaaaa tgcaaaaaga aatggcagaa gcacaagagc tgctaaataa
    17041 aacagagttt acaggtaaag ccaccaatga attggtcaaa gcggttttta caggcgatcg
    17101 tcgcatgaaa gatatccaaa tcaatgaaga agtcgttgat cctgatgata tcgagatgct
    17161 tcaggatctt gtcgtaatgg cagtcaatga tgcgatcgca caaattgatg tggaaactga
    17221 gaaaaaatta gggaaatacg caaaaggttt gccaggattt tagttttaaa ctgaaggagt
    17281 aatgaatatg caatatccag aaccaattgc gaaactgatc gacagctaca tgaaacttcc
    17341 aggaatcggt cagaaaacag cgacaagact cgccttttat acgatcgata tgaaagatga
    17401 agtagtaaat gaatttgcta aatctttgtt aagtgtaaaa cgcgatttgc atttttgtag
    17461 tatctgcgga aacatcacag aagaagatcc ctgcgaaata tgtagaaatc cttcacgtga
    17521 tcgaagcgtt atcctagtgg tcgaagagcc gaaagatgta atggcaatgg aaaaaatgcg
    17581 agaatatcac ggactttatc atgttctcca tggtgtgtta tcaccgatgg aagggacagg
    17641 tccagaagac atcaatattt cttctctgtt gcagcggctg catgatgcag atgtaaaaga
    17701 agtgattatc gcaacaaatg caacaacaga gggagaagca acagctatgt atctctcacg
    17761 tctgatcaaa cccgcaggta tcaaagtgac tcgtctagca catggtctgt ctgtaggctc
    17821 tgatatcgag tatgcagatg aagttacttt attgaaagct gtcgaaggaa gacgtgagtt
    17881 ataaatttct aattaagtgt tttttcagat acaatataaa agcagcacaa gagatggggg
    17941 caacaatgtg aacggactat ttattacaat cgaggggcct gatggtgcag gaaaaaccag
    18001 catcttgaat gaactttacc ctcttttgaa agaagtagca aaaacagaaa tcattcaaac
    18061 aagagaacca ggaggcattc cgattgctga agagatccga gcagtgatcc ttgatccaaa
    18121 aaatgatcgg atggatgaac gtacggaagc actgctttat gcagcagcaa gaagacaaca
    18181 tctagtcgaa aaggttctgc ctgctctggc aaaagggaaa atcgttttat gcgatagatt
    18241 tgtcgacagt tctcttgctt atcaaggtgc aggccgacgc atcggcgtta ccgagattgc
    18301 tcggttgaat gagtttgcta cagaaggtac tacgccggat tttacccttt atcttgacgt
    18361 agattcagac accggattaa gaagaatcaa gaaaaacaga caaaatcaaa tcgaccgttt
    18421 agattcggaa ggtttggaat tccaccagcg tgtacgtcat gcttacttaa agctggcaga
    18481 agagaatccg gaaagaatcc acaaagttga tgcaagaaaa agctttgaag aagtgctgca
    18541 aacaagttat catacaatta ttgaacagta tccgcaattt tttgaaaact aggaaggtga
    18601 acgtttatga aaattatttt agcgattatc caagacaaag acagcaaccg tttatcaaat
    18661 gaattgattg atgcaaatat ccgtgccaca aaactatcat cgacaggcgg cttccttaag
    18721 gctggaaaca gtacgtttat cgtgggtatt gaagatgacc gtgtagaaga agcattggaa
    18781 atcatcaaaa aaacgtgtga atcaagaaag caatttgtat ctacacctgt tacactggat
    18841 atttcgatgg atgggggcgt cccttatcca gtagaagtag aagtaggcgg tgccacagtc
    18901 ttcgtcttac ctgttgaagg attccatcaa ttttaggagg agctgagcta tgaatcaaga
    18961 aataaacttg gctcaaatgc aaccgatcgt gtatcagcag cttcaacgga gttttgagca
    19021 tgggcgtatc gctcatgctt atctttttga aggggagaaa ggaacaggaa aacatgaagt
    19081 aggtatatgg cttgcacagc acctgttctg tacccaaatg aaagacaatc tgccttgtgg
    19141 aaaatgcaac aattgtcagc ggatcgaaaa gaaagaacat ccagatgttt tggttattga
    19201 accggaagga caaaccatca aagtcgatca gatcagacgt ttgcagacgg aattcagtcg
    19261 cagcggttac gaatcaagaa aaaaagtttt tttgatcaaa gaagctgaaa aaatgaatag
    19321 cagtgcggca aacagtttgt tgaaattctt ggaagagccc cctggagatt ttttagcggt
    19381 gttagaaaca gatgcagtag gaagaattct ccctactatt caatctcgtt gtcaagttct
    19441 gcattttcaa gaactttcga aagaagcact gatccatcga ttgcaagaag agcagattcc
    19501 attggaaaaa gcaaaacttt tggctttctt aacaaacagt ttaggaaaag cagttgaaat
    19561 ctctcaagat gaatggttta atgatgctaa ggacttgatt tatcaatggt tcgtttactt
    19621 gcaaaagcaa gatactcaag cctttatcta tgtccaaaaa aaattggtaa aatcatttaa
    19681 agaaaaaaca caacagttta caggattatc tgtcttgatg ttttattatc aggaagcaca
    19741 gcgtcaagca gtagcaaacg gcgaatatgg caaagtgaaa cagataaacc agataattga
    19801 acggatattg atcgcagagc agaaactacg cagcaatgtc agttttcagg ctgttgcgga
    19861 acagttcgtt ttgcatacga ttttttagct tgccgcaaag gatgatgatc aaggaggatg
    19921 gaaatggtag aagtagtagg tgtccgatat agagatgcag gtcatatcta ttattttgca
    19981 ccaggagact ctgaatatgt ttatagtgac aaggtattag tcgaatctca gcaatcctta
    20041 catattgcta ctgttgtcct tcctaaaaaa gagattgatc ccaatgacct tcctgaagct
    20101 atccgtccga tcttgcataa agcgtcacaa gctgaattag aaaaagacaa aaaaaacaaa
    20161 aaagatgctt atgatgcatt gaaaatcgca aaagaaaaag tgcagttgcg tgagttggaa
    20221 atgaaaatgg tcaaagccga atacacattt gatcgaaata aattgatttt ttctttcaca
    20281 gcggacgggc gaattgactt tagagaattg gtaaaagatc tggccgctgt atttcgtact
    20341 cgtattgagc ttcgacaaat tggtgtccgc gatgaagcaa agataatagg cggaattggt
    20401 ccatgtgggc gtccattatg ctgttcttct tttttaggcg atttcgtgcc tgtatcaatc
    20461 aaaatggcaa aagatcaaag tttatctttg aatccaacaa aaatttccgg tttatgcgga
    20521 cgcttgatgt gctgtctgca atatgagagc gaagaatacg agacagcgaa aaaagaactc
    20581 cctgactttg gaaaagtaat tgctacacct gatggtaaag ggaaagtcgt agggttgaat
    20641 ctgcttagcc gtatcgttag tattcggctg actggacggg aaaatcctgt cgaatatgaa
    20701 tgggatgaat tgaaagaatt tatccaagta ggtgagatga atggataaga gatcattata
    20761 cgacggattg aatcaattag aatcagagtt gagaaataca ttaacagaac ttgttgaaat
    20821 gaagcatgct ttgcatgaga tcgtagaaaa aaatacaact ttggagatgg aaaatcaacg
    20881 tctgcgggaa cacctgcggg aattgaacca agttgcacaa gctccagctg aaaatgtgaa
    20941 gcaggaactt tctaagtctc gtatgaatct tgaaaaaatt tatgaagaag gattccatgt
    21001 ctgctacgat ttatatggat caagaaggga caatgacgag ccttgtgcgt tttgtctaga
    21061 agtgatctat cgcgaaagcg gtcgatgacc aataacaaga ggagactgga gcggagaaat
    21121 actgctccag tctttttatt aaggagattg tgacagatgt ataatcaaaa aagtttcaag
    21181 ggaaatccgg tatatgggga tttatatctt gtaccgacgc caattggaaa tttagaagat
    21241 atgagctaca gaagtgttcg tatgctgcaa gaatccgatc ttatcgcaag tgaggatacg
    21301 cgtaatacac aaaagttatt gaatcatttt gaaatccata caccccaaaa aagtttacat
    21361 gaacataatt ataaagaacg tgtccctcaa ttgattgctt tgttaaaaga aggaaaaacg
    21421 attgctcaag tcagtgacgc aggaatgcct tccatcagcg atcctggaca tgagctagtt
    21481 ttagcctgca taaaagaagg gatttctgtg atctctatcc caggacctac agctgggatg
    21541 acggctttga ttgcttcagg gctagtgcct caaccatttt tattttatgg cttccttcca
    21601 cgtaagaaaa aagaacagaa agaaacattg aaaaagctaa aagaacagac agttacgctg
    21661 attttttatg agtcacctta tcggatcact gctacattga cgaatttctt agaaattttt
    21721 ggaaatcgcc aagtcgtttt gtgtcgggaa ttgacaaagg tccatgaaga ataccttaga
    21781 ggaagtacgg aagagctact cgcttatatc gaagaacatc cagtaaaggg tgaatgttgt
    21841 ctgcttgtag aagggaattt gttcgaaatg ccagtgacgg aagttgatga agagttggga
    21901 acgttaaagg aacaagtaga agcaaagatc gcttcaggcg aaaaaccaaa tgctgctatc
    21961 aaagcagtag cgctgaaaaa tgggctgaaa aaacaagaag tctaccgtca gtaccatgaa
    22021 ttagactgag atagtataag ttgtctataa tgaaagacta atgaggaaat cagctactaa
    22081 cttttcaaat ctcttgaacg cgaacgaatg ttcttgtata atgaataaga ggtgaggatg
    22141 atggagctgc aatttccttt acataatgat acatcaagaa aaatcattca tattgatatg
    22201 gatgcttttt tcgcttcggt tgaagaacga gatcatcctg agtttcgcgg acatccatta
    22261 gtaattgcca gacaccccag tgacactggt gggcgtggag tagtgactac agcaaattat
    22321 gaagcaagaa aattcggaat tcattcagca atgagtgcac aaaaagcgta tgagctttgt
    22381 ccgcaagcca tctttaagcc tggcgaccat cataaataca gcgatatttc caaacaagta
    22441 cgggaagtat tctatcgtta tacagatatt gtggaaccag ttagtatcga tgaagcgtat
    22501 cttgatgtga ccgaaaataa aatcaattgc aagtcagcca tcaaaatcgc ccgaatgatc
    22561 caagcagata tttgggagag tgtccagcta acatgttctg cgggagtaag ttacaataag
    22621 tttttggcca aattagcatc agactatcaa aaacctagag gaatcacggt agttgcccct
    22681 caagacgctg tgccattttt aaaagctttg ccaattgaaa aatttcatgg ggtagggaag
    22741 aaaactgtac ctagaatgca tgagctaggg atttatacag gaaaagacct atatgaatgc
    22801 acagaaatga tgttgattcg aaattttgga aaaatgggct attctcttta tcgtaaagtc
    22861 agaggaatcc atgattctcc agtaaacgtt acaagagagc gaaaatctgt gggaaaagag
    22921 catacttatg ggcagccgtt gcaaacggaa gaagcagtgc tgactcagtt gcgccaacta
    22981 gctgaaaaag tagaagaagc actgagaaga gtccaaaaac atgggaaaac agtagttttg
    23041 aaggtcaggt acacggacta ttctactgtg accaaaagag tgacattgcc agaatatatc
    23101 tataaaaaag aagcactctt ttatcaagca agccttatat gggaggaaat cttgggagta
    23161 gaaaaaggaa tccgattgtt agggattact ttgacgaatc tggacccgat gacttatgaa
    23221 aacatcgtcc ttccattatg ggaaaatcaa gaaatataaa aacagctttg agagttgaaa
    23281 ccggaaatcc gttttctctc ccaaagctgt ttttatatca agtcttgctt tttgatttgt
    23341 tcataggttt ctgttgcatc cgtacatttt tcccaaatca caacttgatt ggattctaaa
    23401 gatttttgga cgtcaatgat ccgctggttg ctacttccgc gaaattgtag ttttaggtca
    23461 cgtttgctta attcaaagcg tccgtcaaca aggatatcga tttgcgaaag gagttctaat
    23521 ttatcttctg aatcttgtag caattcatca aaggtatagc ctgtccatga ccagatatct
    23581 tttgtcgtac cgaactcttt tcggatacgt cgtacgactt gcagacaaac atctgtattc
    23641 aaaaaaggtt cgccaccaag taaagttaat ccttgcacgt aatcgttgcg caagtcagcg
    23701 atgatttgtt cttctaattc aggtgtgaat ggtttgccat atcgaaaatt ttgtgcagct
    23761 ttgttgaagc agccttcgca ggcaaataag cagccactaa cgtaaagact gttgcggaca
    23821 ccttcaccat cgacaaaatt aaacggtttg tagtcagcaa tatagttttg gctgtagtct
    23881 tttgctaacc attcttttgg ttttggattt ctcataaaaa aacttctttc atttaaggtt
    23941 caaagatata gctattgaag ataaaatcta ctcgaccaca taaataagaa caaactgacc
    24001 taaatccatt gttcaagaaa gcttgttctt attttgatag agggcgttca aagatacaaa
    24061 gccatcgaaa gagggtggtg aaaaaagact tgtcatagcc tcttattctg aataaacggt
    24121 gttcaaaagc ttgcatctgc agtaataagc ccaactaaac gaaaaatatg aggaactatt
    24181 tttgtttagc tattcttatt acttgatgca ggacagcttt ttcacaacct catttcatgt
    24241 gtttcacacg tgaggaaatt tctttatggc ggccatgtac catcggacga gcttgcggat
    24301 ttcctaaata gccacaagta cgtttgacta catcacatgt ttttggatca tgatttccac
    24361 attctggaca ttcgaaccct cgttctgtcg gtttgaaatc accttcgaaa ccacattgat
    24421 agcaatgatc gattggcgta ttcgtaccaa gatacccgat tttgtcatat gcaaaatccc
    24481 atacagcttc taaagctttc ggattttgtt ggagcatagg gtattcacag tagtggatga
    24541 atccacctga acaatatttt ggataatcct tctcaaattc caatttttca aatggcgttg
    24601 ggtttttacg cacatcatag tggaaactgt ttgtataata ttctttatct gtgatatttt
    24661 cgatgatgcc gaatttttct gtatccaaac ggcagaaacg gtcagttaga ctttcacttg
    24721 gagttgaata gacactgaaa tgataaccat attcatcccc ccatgcatct gcattagctt
    24781 ttaattcttt gacgatatca agtgtgaaag cttttgcttc tgggtttgtt tcccattcgc
    24841 caccgaagaa agctgaagca acttcataca atccaatgta gcctaacgat acagtagctc
    24901 gacggttttt gaataattca ttgacagaat cggtacgtga aagacgtttc ccgaaagcac
    24961 catacatata taaaattggc gcatttgctg gaatggcttc tttacaacgt tctacacgat
    25021 agagaagcgc atctttcatg atttctaagc ggtcagacag taactgccag aatttattct
    25081 gatctccttt tgattcgatc gcgattcttg gcaaattcaa tgtaacaaca cctaaattca
    25141 ttcgtccgac atttacttct tgaccatttt cgtctttcca cccttgcaag aatgaacgac
    25201 agcccatagg tactttgaaa cttccagtta attcaacgat tttatcgtaa ttcagaatat
    25261 caggatacat tcttttcgtt gcacattcca atgctagttg tttgatgtcg taattaggat
    25321 cttcagggtt taagttcaca ccttttttca aagtgaagat cagtttaggg aagatagctg
    25381 tccgcttttc actccctaat ccattgattc gaatctgtaa aattgctttt tgaatttctc
    25441 tttcaaacca gttttctcct agtccaaatc ctaatgaagt gaaaggagtt tgtccatttg
    25501 aagtaaataa ggtattgatt tcatattcca aactttgcat agcatcgaag atatcttttt
    25561 tggtttttgc ttttgcatat tctttttggc gttctggcga atcgatccat tcttccgcgt
    25621 cttttagatg ttttttatag ttcaattctg caaaaggagc aagcaattca tctgttcggt
    25681 cggcagaaca gccaccatat tgacttgacg ctacattggc aataatctgt gagatttgtg
    25741 ctgtggcggt ctggatagat tttggcgatt cgacttcggc attgccgatt ttgaacccat
    25801 tgttcagcat gcctttgaaa tcaatcaagc agcaattcgt catcggtgta taaggatgat
    25861 aatccaaatc atggtaatgg atatcgcctt tttgatgcgc atttgctata tgtggtggca
    25921 acattttcag tccgattgat tttccaacga tcccggctgt cagatctcgc tgtgtattga
    25981 aaacattact gtctttattt gcgttttcgt tcacgacagt ttggtccttg ttgattagct
    26041 tttcaatcga aaagttgata tctgttgctt tactgcgagc aaaatctcgt ttggtacgat
    26101 aattgatgta ctcttctgct aattcatatt cgtttttttc tagtaatata tgttccacga
    26161 tgttttgaat ctcatagatt ttgacatttt cagcaaaccg gcttttgatt tcttggacaa
    26221 ccaagtctgc aatcatttga attttttcat aagtaagtgg tgataatgag ccgtgaattt
    26281 tcttttctgc tttgatcagt gcttcattga tcttttgttc atcgaaatca acatggcggc
    26341 catcgcgttt gatgactttc atctgggatg tctctggctg ctgagtaacg acagtttttt
    26401 cttcataatt tactttcatt atcttcaact cctgctaaat tgttcttgtc tatcataaaa
    26461 caaaatcggg gaaggagcaa ctaaatatcg gctatatata gtattcaatg tgctgtataa
    26521 ttggatttct atactatatg tagtgtatat tttattgtga aaaaaggtga aaacttgtag
    26581 ctggtggatt tgttttttgc atatttaatt ttgctgaata aaataattga ataaaatttt
    26641 ttattcagtc caagtaaaag tgacaaaaac ataagagcaa attattcgta gatatgctac
    26701 tatgcaaata aatagaaatg aaaaatgaaa gaggaggaga agaattggaa aagatgatcg
    26761 aagtgaaaca tctaagtaaa agctacggca gcaaactttc tcccgtcaaa gccttagata
    26821 atatctcatt cacagtagaa gaaggcgagt ttgttgggat tatgggccca agtggtgcag
    26881 gaaagacaac gctgatgaat atcttgtcca cgatcaattt gcctacgatg ggcagtgtct
    26941 cgatccaagg aaaagaaatc acaaaaatga aaaacagtga gctcagtgac tttcgtcgaa
    27001 aaaaactagg attcattttt caagagttca atttgatcga taccctaaat gcaaaagaca
    27061 atatcctatt gcccctagca gttgaacgga tgactaaaga ggaaatggaa aagagagtaa
    27121 gacatgtagc tcaattgttg aatatagaag aactgctcaa acggtatccc gatgaacttt
    27181 ctgtcggaca gagacaacga attgcagctg ctagagcact tgttgttcag ccacaagtga
    27241 tttttgcaga tgaaccaact ggctctttgg actcgaagtc ggctacagaa ttgttgaact
    27301 acttgaagac catgaatcaa aaagaaaaag caacgatact gttagtcacc catgatccat
    27361 atacagcaag ctactgcgat agaattttat ttattaaaga tggtgtgatt ttttctgaag
    27421 ttgtcagaag agggacaaga agagagttct ttgagaaagt aatagacatg caggcgacga
    27481 ttggcggagg aggaaaaatg aatgctgtat aaactagccg ttaaaagttt ttttcggcag
    27541 tcacgaggct atcttgttta ttttttcagt ttgactttat ccgtaatgat ctattattcc
    27601 ttcagcgcaa tgacctacga tcaatcttta gtcagaagag caagtcaaga tacttcgata
    27661 gatggtggat tgagttttgg tggatttatc attactgttg ttttgctttt tttcgtattc
    27721 agtgccaacc gatttttctt gaatagaagg caaaaggaaa taggcatcta tcagcttttt
    27781 ggtatgaata aactgcagat atcaggtata tatgtgttag aaatcatgat aattggattg
    27841 ttcgcctgta tttctgggat attactcggt attatttttt ccaaactctt ttcaatgatt
    27901 ttggttcgaa tgatggatat ggatcttact agtccatttt ttatctccat tccatcagta
    27961 gtagatactt tatttgcttt tttcatcatc cttttagcag tatctgtata ttcaatatgg
    28021 aaaatatggc gctatccaat gattcgaagt tttggagaaa aagaacaagc agatagttca
    28081 acaatgcgct tcaggacaag gcaccgatta ctcgcagtca tcgggttact acttttaacg
    28141 agcggatatt ttggagctag tcattttagg gaaatcactt catggatgat cagttatcat
    28201 tatcttgata cattagtttt cttttttcct tttttaattt ttttcgtttg tgtggtcggt
    28261 acttatttgt ttttctgtta tacatttcgg ttatttttga tcatattgag taaatggaag
    28321 atttattact atggtatcaa ttttttgata atgggtaaca cgcaagttca tttgctcaaa
    28381 agttggcgta caaattctct gattacagtc attctcggaa tttctttaat gacaattggc
    28441 ggcacggcta gtatctctac tattttatcc taccaggaga aagtttcctc cccgatggac
    28501 tatcagtttg atgttgagac agagaaaaaa atcaagccga ttctagcaga ggaagggcag
    28561 aagataacta aagaaatcac cttgcattat aaagtcattg ggagtatcta tagtcaaaat
    28621 ctcgaagaac ctatgtttca aactgctaat ctgatcacgg aaacacaata tcaagccttc
    28681 agaaaagtta atccagattt gccgaacatt tctttgaaat cacctggtca tactgttttg
    28741 cttgatcaaa tgcaaactct ttttcggaat atttcattat atggatctag tattggactg
    28801 ccagataatc aagaattgaa gattcaacaa atgcttccaa gtgtattagg tgacgaaaca
    28861 atggtatatc taagtcctgt actgattgta gatgataccg tttttgaaaa agcaaaaggt
    28921 gtggattatc aagtagtcaa tgtagatgta tcaggtggaa ataatgaaaa aatagatgaa
    28981 cgactgagca atgacctgtc gataaagtgg ctcaatgctg tttattattc ttatgatatc
    29041 gtaaatggaa gtctacaagg agaaattagc acaaagaaac ttccggatga ccaaatgaag
    29101 gaagcacaat ttagccaaga aagctctcgt ttgaatttct cttccagcta ttcgaaattg
    29161 cgtgcagtta atcggcgaat cggtatcaat atttttgtca cactatttgt cgggatgatc
    29221 gtgattattg ctactggtag tattttgaca gtccggcaat tagcagaagc agaggaagaa
    29281 aaagaaaatt atcacctatt gactaagctg gggattccac aaagaaggat cagacggatg
    29341 atcttcgagc aaaacgcact taccttcttt ccacccatga tattagggat cactcacgca
    29401 gtatttgcaa tcaatgtctt cactcagtat ataaaaactg ccgattactg gttggcttat
    29461 cttgtgagtg gcttattgat ccttatctat cttttgcttt atgtcattac gagtcagtta
    29521 tattgtcgga ttatcgagga atgatatacg gaataagaca agataataaa tagaactaaa
    29581 ttttgaatac catttatttg gaataagagg ttgtgacacg atttttgtca caacctcttt
    29641 attttttata ttttttaaaa gtacgagaaa ttataaagaa aaaagcagtg atttgatgtg
    29701 ctatttttat aaaagctatg tgacaaaact gttagtaaaa aaacggtttc tgtaagctag
    29761 acacatgttt ctttttgtca aaattagtta cactttgtgt gaggttatat gaggagggaa
    29821 tccaatgaac aaatggcgtt ctaatccaaa attgaattat tggggaaaat tcatcattcg
    29881 aacaattttt tatagtgcag tactgctgtt cctgatttat ctgtatcact ataaaaatat
    29941 tcaaggagga acttttatct ataacgaatt ttaggaggaa gagtatggaa atcaaaacga
    30001 ttattgaagc aatcgatgat tggggaataa atgaacctga tcgagttgct tatcaggcgg
    30061 atgagacgca tacttttggt gaattgaaac aagcatcaga cgcacttgct tattatttag
    30121 aaaaaaaggt agaaggcgat ggaccaattg tcgtttttgg caatttggag tttgaaatga
    30181 ttgtctcatt tctaggggtt gtcaaatctg gccatgccta tttgccgatt gaagagcata
    30241 cacccaagga gcgtatccta tcgatctttc gggtggctaa accatctatg gtcatcagta
    30301 tcggggactg gatagaagat attccttcgg ttcctgtcat aacaaaaaaa gaatttcaag
    30361 aaatcaagaa gataccagta ggattttatc ccagaaatag cgtaaaaggt acagaaaatt
    30421 tttatattat ttttacttct ggtactactg gagaaccaaa aggcgtacaa atcagtcatg
    30481 ataatctagt cagctttgtt caatggacga tggaagactt tgggatcaag cctggtatgc
    30541 atttcttagc ccaagcgcca ttttcttttg atttatcggt attttctatt tatcctgcat
    30601 tagtttctgg cggaatgctg aagccgttaa ataaagcagt tgttcaagac tttcgtcaat
    30661 tattcgcgac attgccagcc ttgaagttga atgtgtgggt ttctactcca tcatttatgg
    30721 atatttgctt gatggaacct acattcaatg gagaaaatgt gccggaattg gacatgtttt
    30781 tattttgcgg agaagaattg acgaaaaaaa ctgcagaaag tctacttgat cgattcccaa
    30841 atgcacggat atataatact tacggtccaa cagaagcaac tgtagctatt tcaagtattc
    30901 agattgacca gcatgtacta gatagttatg accgactacc gattggctac gtaaaaaaag
    30961 acacgaaagt ttctattgtc caagaaggta aacctgtttc aaaaggagaa acgggtgaaa
    31021 tcattattgc aggaccaagc gtatcaaaag gttacctgaa caatcccgaa aagacagctg
    31081 ctgcgttctt ttgtcaaaat gacttagcaa gttaccatac aggggatgca ggtagactag
    31141 atgaatatgg gcttttattt tatgaaggac gtatggatca gcaggtcaaa ttacatggat
    31201 accggattga actcggggat atcgaacatt atctgctcca agacaaccga atcaaacaag
    31261 ctgtcgtcgt accaaaatac caaggaacaa aagtacagca gctggttgct tttgtcgtat
    31321 tagaaaacaa aacgaaacag ccggattttc agttgactaa atctatcaaa gaacaattac
    31381 tagaagttgt aatggattat atgattcctc agaagttcca ttatgtcgat ctgctgcctc
    31441 agacagttaa tggaaaaatc gatcgaaaaa aattaacagc tgaggtgaat cctgaatgat
    31501 gttacctcat atgatccctt atgcagagcc gttttatttt tttcttttag ccattgcgct
    31561 tgtaccgatc gttctatctt tattgatatg ggaaaaaaga ttaccagttt atcaatcagc
    31621 agtgacactt ttctttttat ttgtcagctt tggaggtaat tattggcaac agggagcggc
    31681 gctgattggg tatgttttgt ggcagacgat acttgtatgg ggctattttg tttatcggca
    31741 aaggaaaaat cagacaggat ggttttttgc cgccgttatt ttagcgataa ttccactgtt
    31801 tttaacgaaa gtgactcctt tttttgaaca tggaaaagca tcgttacttg gttttttagg
    31861 aatctcttat ttaaccttta aatctgtaca aatgatcatg gaaataagag atggcatgat
    31921 caaaacatat aagccatttc gttatatcca gtttctgctg ttctttccaa caatctcttc
    31981 tggaccaatc gatcgctata ggagatttga aaaagatcag ctccatccgc ctgttcgtga
    32041 taaatatgtt gatcttttgg gaaaaggcgt ccaaaatatt tttgtcggtt ttttatataa
    32101 attcattatc ggttattatt ttggtcaagt actgcttcct gtagtgggac gcattgcctt
    32161 acagcatggt ggtatttcat gggcattagt aggttatatg tacgtgtaca gtatgtattt
    32221 gttttttgat tttgctggct atagcttatt tgcagtcggt acaagctaca tgatgggata
    32281 tcagacacca atcaatttca ataaaccttt tttatcatgg aatatcaaag aattctggaa
    32341 tcgttggcat atgacgctgt ccttttggtt ccgtgattat gtatatatgc gattgatgtt
    32401 cttcatgatg aagaaaaaat tttttaaaag caagatcgta atgtcaaata tcggttattt
    32461 tgctttgttt cttctaatgg gtatatggca tggattgacg tggtactaca tcgtatatgg
    32521 actgtatcat gcttgtctga tctgtctgac agatgcatgg atccgattta agaagaagca
    32581 taaagagcag ttgccttcta acaaatttac gcatggctta gccgtatttt tgacatttca
    32641 agcagtatgt tttagcttcc tgattttttc aggattttta gataaacttt tttttagcta
    32701 acgaatagtg acatattaat ttatataaca aaggagaaaa ggaaaatgga agaacaaatt
    32761 ttatcaatct tagaagaaat aacaggaaca gatgaagtaa gaaaaaatcg tgatattgat
    32821 ctatttgatg aagggttgct tgattcttta gcatctgttc aattattagt cgagctagac
    32881 ggagagctgg atatccaagt ccctgtatct gaattcgagc gagaggattg gtgcacaccg
    32941 aataaaatca ttcaacaagc aactgcattg aagggttgag tatgaaaaag aaactttttg
    33001 ctattttcgg cccggttgtt ttagctgttg gcttactgtt tgtgtttttt acctcctcct
    33061 atcaagtaga tatctctaat ccagaaacga ttagacgtgc ctcttcttcc atgtcagtga
    33121 acgtgttgaa aggagatgcg ataaaaaatt atgcattatc tgaaaaacaa tatattcctt
    33181 tttttggctc aagtgaatta agcagaatca gtccatttca tccgtctgtt ctggcagaaa
    33241 aataccagcg aaactatcgt ccatttttgc tgggagcacc cgggacacaa tcgttaagcc
    33301 aatatatgat gatgcgttct gcaggagatg ctatgaaaaa caagaaagtc gtctttatta
    33361 tttctcctca gtggttcgtt aaaaatggtg taaaaactga ttactttaat acgtattatt
    33421 ctgaacttca aacatacgac tggttgtttt caatgaagaa agtaacgcct gctgatcgct
    33481 atttagctag aagattatta actttctcaa aagtaaaaga gaatgatacg ttgacggcga
    33541 ttctgcaaac gatcaaaaaa gggaagctac ctttacctga atctttgaat cagctgcgca
    33601 gccaatggaa catgctgaag agagaggatg aagtattcag caatattggg ttgaaagatc
    33661 gacagcaaaa aatcgatcat gagtcaaaac gattaccaaa acaataccaa gaaacagaat
    33721 tatccatttt agcaaatcaa attggagaac gagaaacgac gaataatcca ttcgggttga
    33781 aaaacgattt ttatacgcat cgtatccgag cccacgagcc agagctcaaa cagtcacaaa
    33841 aaaattggga ttatcgtttt tcgccagaat tttctgattt tcagctggtc ttggatcaat
    33901 tagcaaaaaa ccataacgaa gtattgttca tcatcccacc ggttaacgag aaatggagcg
    33961 attataccgg actatctcaa gaaatgttac aaggatttgc caaaaagatc aaatttcaat
    34021 taaatagcca aggattcaat cgaatagctg attttgtcaa tcaagcgggt accaactatt
    34081 ttatggaaga cacgatccat ctaggctgga aaggctggtt ggctgcagat caacagatca
    34141 gaccgttttt agaagaaaat catattactg ctagtaagta tcatcttgac gatgcttttt
    34201 ttagcaaatc ttggcaacat caaataccag ataaactaca attaaaataa agaaaacagg
    34261 cgagtgttgc tcgcttgttt tctttatttt tgaatattct gaataaaaga taaaaatacc
    34321 aagtttgcct gaacaaaaat cataagcaat ggtataatca caatatgaat atagaaatgg
    34381 gggaaaacat ttggatacaa aagaagaaca gctacttatt gatttaactt ctgcaaaagg
    34441 agtacctgga aatgaagaag aggtaagaga agtattcaga gaatatgcca aaccattcgc
    34501 tgatgatatt ttttatgacg gtttaggcag tgtgattgcc aaacatggtg ctggcggagg
    34561 ccccaaggtc tttatttctg gacatatgga cgaagttggt tttatggtaa caaaaataac
    34621 cgaaaaagga ttcttggaat tccaaactct tggaggttgg tgggggcaag tcatgcttgc
    34681 tcagcaagtt gaaatcaaaa cacgtgaagg gaaaatcgtc cacggtgtga ttggttccaa
    34741 accaccacat gttttaacac ctcaagtaag aaataaacct tatgaaataa aggatatgtt
    34801 cattgatatt ggcgcatcaa gccaagaaga agccaaagag tggggcatac gtcctggaga
    34861 tatggtcact ccatatattg aatacaaacg aatgaatggc agtaaatatt tactggcaaa
    34921 agcatgggat aatcgtatcg ggacagctgt ttctctgcga gtattagaga atctatctaa
    34981 agaagcacac ccaaatgttt tattcgcagg aagcgatgtg caagaagaag taggcttgcg
    35041 aggtgctcga acaagtacac accttgtaaa tcccgatatt gcttttgctt tagatactgg
    35101 tacagcagga gacactccag gaatgacacc aaaagaagca gattcgattt taggaaaagg
    35161 cccacagatt ttgatttttg atgcatctat gatcccgcat aaaaaattat tgaattttgt
    35221 tattgatgta gcagaggaaa tggatattcc attccaatat acagtgattt ctggcggagg
    35281 aactgatgca ggacaaatgc atttgacaag agatggtgtt ccgtctgtag ccattaccgt
    35341 tcctgttcgt tatctgcatt cccatacatc agtgattcat gaagatgatt atttgaatac
    35401 agtgaaacta gtcacagaat tagtgaaacg gcttgatagt gaaacagttg aaaaaattcg
    35461 gagttatgaa taatgaataa tagaatacct atttctgaat atcggaaaaa agcacgagtt
    35521 tctttggaaa atcaatgggg aatcaatact tggcttgttt tcttatctat aatatttacg
    35581 agcgtcatcc agaacttttt tgacggtttc agtccttttc cggaagaaag catgcagcag
    35641 cacttattga gttttctagt cgataattta cttttattcg cattcaacta tgcattgttt
    35701 tacattgcgc tagtagttgt acggggtggc agaccaaaaa gtaacctttt attttcagtt
    35761 ttccaaagaa agtattttgg ttcgatactt ggcatcaatt tgatcaattc agtcatcaac
    35821 tggctactca acagtttaat ctttctgccc atgtttttaa tcagcggagt gagtacttat
    35881 atgcagctgc ttttcagttc aaatgcggta cctacgggtg tcatgccaga agattttctt
    35941 gatatcagct ttgttttatc gatgataggg atgatttttg tttcagcact catcatgagt
    36001 attgttggcg gtttattcca atttgctgca tggacaaagt tcgactatcc tgatttgtcg
    36061 gttattcaat gtttgaaata tggctggttt ttattgaaag atagaattgg tacgtatatt
    36121 ttgttgcagc tgtcttttat cggctggtat ttgctaggag caatcgcttt gttcatcggt
    36181 cttttgtggg tcattgttta tgtgaatgtg tcagttgcag aattttatga acaagcacgg
    36241 attgaaaaag gaggtccaga cgcctatttt acttagcatg taagcagttt attcatcaaa
    36301 aaaataactt ttgtggtagg ataaatcttt gagggggaat gtacgatgaa attaactgtt
    36361 ttaggatgct taggagcgta tccttataaa aatcaaggga caacaggtta tttgcttcaa
    36421 tctgacgggt tcaatttgtt gatcgatgca ggtagtgcta cgctgatcaa attacaagaa
    36481 caccttgatc cacttgatct agatgctgtg atccttagcc attatcatca tgatcatatt
    36541 gctgaccttg gtgtattaca gtattactgg caacttcatc ctaagagaaa tccggagaca
    36601 ttgctttcaa tttatggaca cacaaaagat tccattcact ttgaagaatt gacgttggaa
    36661 aatgtctcaa aaggacatcc ttattttgaa gctgaagaat taaaaattgg tccttttctg
    36721 attactttta tggaaacaat ccatccagta gtatgttacg ccatgcgtat cgtagaagaa
    36781 acaacgggga aagtattcgt atttacaggt gattcaggtt atttggaaag tttcgctgat
    36841 tttgcgaaag atgctgattt gtttctagca gatacctatc tttttgaagg aaatgaacat
    36901 catcatgccc atttcacttc aaaagaagct ggagaacttg cgaaatcagc taacgtaaag
    36961 aaacttgtac ttacacacct acctcagttt ggtgatttag aacaattgaa aaatgaagcg
    37021 caaaaggcag caggcaaagg gattgatata gaacttgctg cagttgacaa agtgtttaac
    37081 atttaggagg aagaacatga tttttgtacc aaatgaaaac cacgacccaa gaatcaattt
    37141 agcaattgaa caatatttgc tgcaagaaat gcctttagat gaacctattt tgctctttta
    37201 tatcaatgaa ccttcaatca tcatcggcag aaaccaaaat acgcttgaag aaatcaatcg
    37261 agattatgtg gaagaaaatg gcattcatgt tgtccgtcgc ttaagtggag gcggagctgt
    37321 ctaccatgat tttggaaacc tgaactttag ttttatcatg cctgatgatg gggattcatt
    37381 ccgtgacttt gcgaaagtaa cacagccaat catccaagca cttcatgaat tgggtgttgc
    37441 tggggcggaa ttgaaaggcc gaaatgatct agtcattgat ggcatgaaat tttctggcaa
    37501 cgcgatgtat gctaccaacg gtcggatgtt tgctcatgga acaattatgt tcgactctga
    37561 tatcaatgaa gtagtcaatg cattaaaagt aaaaaaagac aaaatcgaat caaaaggaat
    37621 caaatcgatc cgttctcgtg taacgaatat caaaccattt cttccagaag aaaagcaaaa
    37681 aatgacaaca gaagaatttc gtcaagaaat cttgttgaaa attttcggcg tagagtcagt
    37741 agaagaagta aaaacgtacg aattgactga tgaagattgg aaaaaaatca atcgaatctc
    37801 tgaggaatat tatcgaaatt gggattggaa ttacgggaag tctccagatt tcaatttctc
    37861 tcgccaaaaa cgtttttcta tcggttcgat tgaagtccat ttgaatgtct cagaaggaat
    37921 gatcaaagaa gcaaaaatct ttggcgattt cttcggacta ggagatatct ctgacgtgga
    37981 aaaaaaattg gttggacaga aatatgataa agcatctcta tcaaaaatag tcagccaaat
    38041 tgatgtgaag aaatattttg gtgcgataga accagaagaa ttgcttacct tactttattg
    38101 aaaataaaaa atagcggaat ccacatatat ggattccgct attttttata caggattcgg
    38161 gtaatttcga gagagttgaa cagtgatccg atcaatgaaa gtatcttttt cctgcgttag
    38221 tgttcctgtg taacgatccg ctacgtcttt catcatcatt aagtcaaaac gttcctgatc
    38281 atctaattct tctgtgatgc ctcgactaaa taggtttgta tcgtaatgtg cactatgttc
    38341 gcaacaaatg acgaaatgtt cctcttgttc gtgtatcgac aaataaattt ttcgatacag
    38401 tggattttcg atggcatgag tttctctaaa ggaatgctct aaagcgtgga tcaaaagttg
    38461 agccagatcg tcatcgttga taggaagttc ttcgggaaga tctgcttgga aggttatctg
    38521 aatattccgt ttggcagcta acttctggta acgcgctaag ataagatttg tcacctggtg
    38581 gttgcaaaaa gaacacagca tttcgaaatt ttttgcttct tctaatatct tttccacata
    38641 gtttttagct tttgtttggt ccgtatgcat taaatcttgc agattctcca tctcttggac
    38701 aaattccagg cgaagtgtat ttacttcttg gatatgctgt cgaagctgct cataatgttg
    38761 ctccaacaaa tcatttttga tttttaagaa atctacttgt ctccgatctt tgtcggtatt
    38821 taagatgtga tcgattagat tgtagctgat aataacgatt agaatgataa tatataaaat
    38881 cgtagaccaa ttgatcgttg tttgatagat acctaatgcc gtttggatgt aaatcaagca
    38941 atggataatg gctaccaaga cgatccaagg tgtacaagct acataaaaac ggttattctt
    39001 atatgcttcg ccaatgcatg caagtgaagt gactaaagtg cttataacac tagcaatatt
    39061 agcaatcggc attaattcag gaagttctgc aggagtaaaa gttgcataaa gcagaacgcc
    39121 gataaaaatc aaaagttgga acgtacaaaa aattccgtac cattttttat agtaaaacat
    39181 tcggctccaa tagtagcaga tgatgaaagc tgacgttaag ataataaata aatgagataa
    39241 aaaagaatga acgaatggtt caaaaagaat accacttaaa atatcttctg atacagcttc
    39301 aaatcctaat gccaaagcaa agcaacttaa gagaataagt gagtattcaa gacgtttttg
    39361 tttatacatc aagtagatcg tatagaaaaa ggtccctata gcgataaaaa cagcgattat
    39421 catcgtcaat acttgcggca ctgattgtga ataaataaaa ctaatcaatg gtccagttgt
    39481 tcctagataa actttcggtg gcagtccagc atagttctga taaggagatg agactgtaag
    39541 ggtcaatttt tttccgatat aatttgctgg taaatctatc acagccaatg agagtccggg
    39601 attgctttct tcctgataat ctttccgttg gtataaaatc ttttcgccta gatatacagt
    39661 aatccattga tggtttcctt tgattagtaa atttgcttcg tccaacggtt tttcaagtgt
    39721 cgtttccata atgaatgttt cgtctttatc cacggtagga atcgtacgag tgtacttgct
    39781 gtcaaactta aaatcaggat catcttttgt atagaaaacc cacgaatctt ttatttcttt
    39841 catttgattg ctgtccgcag gagaaaaaat aaaataaaag aaataagcaa ttcctgttaa
    39901 aaataacaat g
//
LOCUS       DAZUJR010000014        39874 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.014, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000014 DAZUJR010000000
VERSION     DAZUJR010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39874)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39874)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39874
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.014"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(33..578)
                     /locus_tag="ACG804_000706"
     CDS             complement(33..578)
                     /locus_tag="ACG804_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HFS4831657.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(590..1282)
                     /locus_tag="ACG804_000707"
     CDS             complement(590..1282)
                     /locus_tag="ACG804_000707"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HFS4831658.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(1301..1585)
                     /gene="macP"
                     /locus_tag="ACG804_000708"
     CDS             complement(1301..1585)
                     /gene="macP"
                     /locus_tag="ACG804_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HFS4831659.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(1598..2161)
                     /locus_tag="ACG804_000709"
     CDS             complement(1598..2161)
                     /locus_tag="ACG804_000709"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFS4831660.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            2389..3051
                     /locus_tag="ACG804_000710"
     CDS             2389..3051
                     /locus_tag="ACG804_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HFS4831661.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            3175..4371
                     /locus_tag="ACG804_000711"
     CDS             3175..4371
                     /locus_tag="ACG804_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HFS4831662.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(4472..5848)
                     /locus_tag="ACG804_000712"
     CDS             complement(4472..5848)
                     /locus_tag="ACG804_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFS4831663.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(5885..6751)
                     /locus_tag="ACG804_000713"
     CDS             complement(5885..6751)
                     /locus_tag="ACG804_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HFS4831664.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(6840..7865)
                     /locus_tag="ACG804_000714"
     CDS             complement(6840..7865)
                     /locus_tag="ACG804_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFS4831665.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(7883..8557)
                     /locus_tag="ACG804_000715"
     CDS             complement(7883..8557)
                     /locus_tag="ACG804_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFS4831666.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(8741..9634)
                     /locus_tag="ACG804_000716"
     CDS             complement(8741..9634)
                     /locus_tag="ACG804_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFS4831667.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(9708..11405)
                     /locus_tag="ACG804_000717"
     CDS             complement(9708..11405)
                     /locus_tag="ACG804_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFS4831668.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(11398..12711)
                     /locus_tag="ACG804_000718"
     CDS             complement(11398..12711)
                     /locus_tag="ACG804_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
                     /protein_id="HFS4831669.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(12711..16652)
                     /locus_tag="ACG804_000719"
     CDS             complement(12711..16652)
                     /locus_tag="ACG804_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFS4831670.1"
                     /translation="MEKLDEPIVPSGQALQRIQRQLFNGILERLGPTATQDPYEYIYP
                     SGEVENEQHRYPKFTTNDYTKVLGNWTQSNERYQGDKGSPYDGENLIDDSDYTNGGAN
                     WRNYDYATNNGSTAGEEDRNVPAQTVQLWGNERNFENSYLDYNGAYIKKWVEPVLPSS
                     TASDLHPEDATTLYNVYLDVIGGEKKEISPIDIVFVLDKSASMSELTAGTNSQTKNAA
                     LIEAVNEMSKDLLSDPSLDIRIGMVNFYHNSTAINNHEQISSDIFPLTNDINRLTGSE
                     NTALNRTPIGGTPLTLGLKNGYETLYKDNGGENRNPEKILIVVGDGTPTFSYAPIQSS
                     YRTSTNGAWSNWTVMEDKIAEDNDVLFRNFEEFSGNTSNAGFTHPVTYASDFNRPEDE
                     VNVHYRYGEVKEGDNKATHWVGDGSSNNNTNGSPTSQEKSSAINTVAYHHWLKNKYQE
                     NPPSIFSIGLGIDGNVSGRQRLDAIGRNVLKNIADLEEDGVTPRYYNANNKNDIVTAL
                     EDISSTFKRTIQQATLYDETGFNVSPFGAGRSADIQFYHLDPGENGMKYQEPEIWDEE
                     RHGQAPPEVVATPTTYVGRENQAYKFSPISLGEGEMVRIKYQVKLDAGAQDGNFCTVN
                     NMAYIQNLEDYENDITTGRMYFPSSSIRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQ
                     NPESGEAEPIETSKTTTDGIAIFETKMPILGDETGAVSDIFWIREIAGPPRYQLVDET
                     YQFQIKKYAANEDEMLGHYELVDEYTSGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNI
                     EGTEYDELYVKLEMRNEFKPIHMNINKLIEGSNMPINGAEFELYETDGNGLEIGYPVA
                     KGLSGVNEVEEEKGRLTFYSVDEDGKYVIVDGEKVIHPIGEPDSFVYKDSEETTNYAE
                     YKIIESQNPEGFKEPDENDTWILRLYDNAIGTIQLKQTGEENWQYLTYTTDEEDRLWV
                     AFTAYNTFDYREIRVRKLDHEGHTLDGAGFDIRKVGDSSFPLYRAYTGNPLEPEESKR
                     LPGIGYFYSRAVGVEKYVDLNYDQPLHLSIGEYEVSESVAPNGYRLSDQVFQFALNEE
                     GKFIIEDTVIEDETAPLPEGYEIIDGVLQVTLEDELAPIDLELLKIDSMNSRRLEGAE
                     FSIEKQNSAGEYEIIEGGLAPDPNDSSLFNASDLLEGVYRIKEVKSPDSYRKLPGYFI
                     LEISYREEPDIENDRVVPGKEAGTLKVEISYYPNEEAETPDLQQELEYELLETNRIRL
                     QLSVGNDPENPLPATGGSGRLFYILLAAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(16761..17219)
                     /locus_tag="ACG804_000720"
     CDS             complement(16761..17219)
                     /locus_tag="ACG804_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFS4831671.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(17517..18035)
                     /locus_tag="ACG804_000721"
     CDS             complement(17517..18035)
                     /locus_tag="ACG804_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HFS4831672.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(18037..18654)
                     /locus_tag="ACG804_000722"
     CDS             complement(18037..18654)
                     /locus_tag="ACG804_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HFS4831673.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(18651..19505)
                     /locus_tag="ACG804_000723"
     CDS             complement(18651..19505)
                     /locus_tag="ACG804_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4831674.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(19502..20413)
                     /locus_tag="ACG804_000724"
     CDS             complement(19502..20413)
                     /locus_tag="ACG804_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4831675.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(20454..21788)
                     /locus_tag="ACG804_000725"
     CDS             complement(20454..21788)
                     /locus_tag="ACG804_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFS4831676.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            21996..22826
                     /locus_tag="ACG804_000726"
     CDS             21996..22826
                     /locus_tag="ACG804_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HFS4831677.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(23070..23319)
                     /locus_tag="ACG804_000727"
                     /pseudo
     CDS             complement(23070..23319)
                     /locus_tag="ACG804_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(23510..23704)
                     /locus_tag="ACG804_000728"
     CDS             complement(23510..23704)
                     /locus_tag="ACG804_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831678.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(24209..24394)
                     /locus_tag="ACG804_000729"
     CDS             complement(24209..24394)
                     /locus_tag="ACG804_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831679.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(25244..25585)
                     /locus_tag="ACG804_000730"
     CDS             complement(25244..25585)
                     /locus_tag="ACG804_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFS4831680.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(25585..25815)
                     /locus_tag="ACG804_000731"
     CDS             complement(25585..25815)
                     /locus_tag="ACG804_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFS4831681.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            26102..26440
                     /locus_tag="ACG804_000732"
     CDS             26102..26440
                     /locus_tag="ACG804_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831682.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(26645..27207)
                     /locus_tag="ACG804_000733"
                     /pseudo
     CDS             complement(26645..27207)
                     /locus_tag="ACG804_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349929.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
     gene            complement(27939..28520)
                     /locus_tag="ACG804_000734"
     CDS             complement(27939..28520)
                     /locus_tag="ACG804_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFS4831683.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(28703..29329)
                     /locus_tag="ACG804_000735"
     CDS             complement(28703..29329)
                     /locus_tag="ACG804_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HFS4831684.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(29351..30682)
                     /locus_tag="ACG804_000736"
     CDS             complement(29351..30682)
                     /locus_tag="ACG804_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HFS4831685.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(30837..31238)
                     /locus_tag="ACG804_000737"
     CDS             complement(30837..31238)
                     /locus_tag="ACG804_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HFS4831686.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(31324..31530)
                     /locus_tag="ACG804_000738"
     CDS             complement(31324..31530)
                     /locus_tag="ACG804_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831687.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(31625..33127)
                     /locus_tag="ACG804_000739"
     CDS             complement(31625..33127)
                     /locus_tag="ACG804_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HFS4831688.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(33145..33600)
                     /gene="argR"
                     /locus_tag="ACG804_000740"
     CDS             complement(33145..33600)
                     /gene="argR"
                     /locus_tag="ACG804_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFS4831689.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(33698..34315)
                     /locus_tag="ACG804_000741"
     CDS             complement(33698..34315)
                     /locus_tag="ACG804_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFS4831690.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            34536..35909
                     /locus_tag="ACG804_000742"
     CDS             34536..35909
                     /locus_tag="ACG804_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4831691.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            35984..37096
                     /locus_tag="ACG804_000743"
     CDS             35984..37096
                     /locus_tag="ACG804_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFS4831692.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(37168..38805)
                     /locus_tag="ACG804_000744"
     CDS             complement(37168..38805)
                     /locus_tag="ACG804_000744"
                     /EC_number="4.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004612 - phosphoenolpyruvate
                     carboxykinase (ATP) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HFS4831693.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(38973..39581)
                     /locus_tag="ACG804_000745"
     CDS             complement(38973..39581)
                     /locus_tag="ACG804_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFS4831694.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
BASE COUNT        11475 a         8464 c         6910 g        13025 t
ORIGIN      
        1 tgctttttat tttatcaaat cactttgttt ttttataaaa tttctgcgcc tagtgtggac
       61 tcaaaatgtc tcaatgccca ttcatgtcca acgggatcga aacttgccac ggaatctttg
      121 aaaatatgga gtttgtatcc tagattatac gcatcgactg ctgtatgcaa cacacagata
      181 tctgtacata cgccggtcaa ataaatatct gtgatctggc gttctcgcaa acggatgtct
      241 agatctgttc cactaaaagc ggaataatgc cgtttgtcta tccaataaac attttcctct
      301 tgctcatagt cttggtataa actttttaaa gagccgtaca attcccgtcc acccgttcct
      361 atcacattat gcggaggaaa taagcggttc tccggatgaa aggaatcttt tggatcatgc
      421 gcatcaatgg caaaaacgac aaaatccttt tgatcaataa acttctttgt atgagcagtc
      481 agcttttttt caattacttg tcctgctgtc ccagtagtca gctttccatc ctctgcaaca
      541 aaatcatatg tgtagtcaat cgagatcaat gcgttcatct tagtcctcct tatacgagat
      601 gtttgacaaa ttcgatcacc atttctgctg atcgtttgcc tgcgtcttcg ataaattcgt
      661 caaagctttg tgtcgccgag tgatctgctg tgtcgctcat tgcacgtacg atcaaaaatg
      721 ggatattgaa ctgacgagct gtttgtccaa cagcggctcc ttccatttcg caagctaatg
      781 cttcagggaa attcgttaag atttctttga ttttatctgg cgagtcgaca aatgtatcac
      841 ctgtaacgat caatccttct tttgcgttca aattcgttgc ttttgctgct ttaaccattt
      901 cactgcgcaa atatgtgctt gcttcataat atagaggcat tcctggtaat tgtcctgggt
      961 tgtagccaaa tcctgttgca tctgcatcaa aataagctac tttgtctgat ataacgatgt
     1021 cacctacttg taagccttca ccgattccgc cagctgaacc tgtattgatc accatgttca
     1081 cgccgtattg ttggatcaac agacttgtgg taatagatgc taagactttt cctataccgg
     1141 aacgtacgac gatcacttcg tggttaccta atgaacctga aataaataaa gcgcctgcgc
     1201 gttcccatga taatggttcg cttaggttct ctctcaaaat ttttacttct tcttccattg
     1261 cgccgataat accgattttc atctttttaa ttccttcttt ctatataaat gcgattgcta
     1321 aaaaaaccac acataacatt aggataacaa taataagaga tttcatcaaa aaagagttcc
     1381 atttggtcgt cttttcccgt tcgctgatcc ttgttttcgt gattggttta ttctttttgc
     1441 tttctttacg ataaaagctg gcaatctttt tttcttcttg ctgataagct gtttctgctt
     1501 ttcgctgttt ttttaatgac tcgcttgctt gtgcttgttg tcgcttgcga agttcgcttc
     1561 gcgtaataag cggtcctttg gccataagcc gatccctcta ctttcctttg gtcaatagtt
     1621 cccagtattg aatcgcataa atcgtctttg catcacaaat caactgatct ttcatcgctt
     1681 gttgcgcctc ttcaagagtt agatgataca actccagtac ttcgtcttca tcttgtgcta
     1741 aaggattctc gaccttctct accccttgtg catgataaat atgaaggact tcatttgcaa
     1801 aacctggtga aagatacatc gaagtaagat ggctcagcga cttcgcacga tagccagttt
     1861 cttcttctaa ttctctagct gctgtcattt cgggattttg tccttctcct ggatcgattt
     1921 ttccagctgg aatctccaaa atcacttttt ctaaaggttt tcgaaattgt ttgacaagaa
     1981 gcagacgatc ttgttcgtca aaagcaatga tcccgacacc gccaggatga aataccagtt
     2041 ctctcttcga agttcctcca tctggcaaac gaacttcgtc tacagcaaca tcaataattt
     2101 ttccgctata gatttctttg cgactgattg ttttttcttc aaattgctca ttgttcagca
     2161 tatcttctcc tgctttcttt gtaatcataa ctgctttttt ttcatttttc aatttttctc
     2221 aaaaactcct tattagttta ccatagataa accttagatt ttctctaaat atagaaaatc
     2281 cttctttagt ccgatactct ttctagtagt ccgtatgcta aaataagtat gtaatcgaat
     2341 aacgaaaaga attcaatact caacgataaa tgacatggag ggtttattat gataaaacga
     2401 aattggccgt ggcttctagc attggtcttg ctatttctct ttgtccgaaa caatagtttt
     2461 tcttttgttc taggactttt attgataggt gtagttttag ttttgtgggg actctttggt
     2521 tcgcgcagga aaaagggaaa acaagaagaa attcctgcac tgactgacga acttgaaact
     2581 cactatgaaa aaagcggtat gacagcgaat gaaatttcat tttttcgaca aacaatgaat
     2641 caaacaaaaa atgagatcaa tcaattgcaa atgaatatgc agcagacagc caaacttaaa
     2701 gcaatcgatc tccgccatga tccagtcaaa gcagcgaaag ctttattcaa agaattggtg
     2761 aaagaaccaa accgactgca tgaagcaagt cagtttcttt atacgcatct gccgaatcta
     2821 gttgatttga caaataagta taatgagatc aatgaccatg agatcaaaaa caaacagacc
     2881 tatgaaaaac tagaagaaag cgcgcagatc atcgaccagc tgtcagcttt aatcgcacaa
     2941 gattatcaaa aattcgttgc tgaggatcta gatgatatcg acgtagagat atctgttgcg
     3001 aaacagagct taaagcgtga taataaatat gaaccagaac aaaaggatta actcttttgt
     3061 tcataaaaga agactcggaa cattcagatg atgtctggct gtttcgagta ctttttctaa
     3121 agtagagaca ttcatgtaag aatcgagaac agattcaaca aggaggaatt ttttatggat
     3181 cataaaccga ctgaaacaaa agatgttaca ccagttaacg atacacttga agatttattg
     3241 aacaacccgt tttcaactcc aacagatacg ctgaccactt cacaacaagc ggagattgat
     3301 cagctccaag agcaacagac agctgctcgt ttaattgaca aactaccggc ggaacgccaa
     3361 gaacaagcta aacagctagc agcaaaaatc gatgctaatg atgcacagtc tgtcatcagc
     3421 tacggatcgg ctgcccaagc aaaattaagt gaattctcac aatcgatgtt gaatcatgtg
     3481 caagcacaag atattggtcc tgtaggagat tccttaactg aactgatgta tcgtctccaa
     3541 gaagccaatc ctgacgaact gcgtgccgga gaagggaaca tcttccagcg tgtcttcggg
     3601 aaggtcaaac aatcgatcta tgaagtgaca gcaaaatatc aaaagattgg tgcacaaatt
     3661 gacaagattt cagtgaaatt agataaagaa aaagacggtc tgctaaaaga taatctgatg
     3721 ttagaacagc tttaccagaa aaacaaagac tactttgatg cactgaatat ttatatcgct
     3781 gctggagaat tgaaaatgga agaacttcaa acaacgatca ttccagaagc gatgaaaaga
     3841 gcagaagaaa ctggcgatca gatggatgtt cagattgcca atgattacac gcaattccta
     3901 gatcgtctgg ataaacgtac gcatgatctt cgcttagcta gacagatcac gatccagcaa
     3961 gcaccacaaa tccgtttgat ccaaaacaca aatcaggcct tggctgaaaa gatccaagca
     4021 tctatcgcta cagccattcc gctgtggaaa aaccaagtcg tgatcgcatt gaccttgctt
     4081 cgtcaaaaag atgcagtaac tgctcaacgc caagtctctg aaacaacaaa cgacttattg
     4141 aagaaaaatt cagaaatgct gaaaatctca gccatcgaaa cagcgaaaga aaatgaacgt
     4201 ggaatcgtgg atatcgagac ccttcaaacc actcaaaatg atttgatcga aacaatccaa
     4261 gagacattgc gtatccaaaa agaaggaaaa gaaaaacgtc gtcatgcaga agtagagctt
     4321 ggacacatgg aagaagatct gaaacaaaaa ctgttggatt taacccaata gatcaccttt
     4381 cgcttgttac taaaacaaac gcccaacaac agtttattac aactgttgat gggcgttttt
     4441 cttatctttc ttctaacttc tccattggag tctatttctc attcatcttg ctgtgtccat
     4501 agccatagcc aaaataaatg atcagtccaa taaccattac gataccgaac acgatccatg
     4561 tcacagtttg cagacgaagc atcaatacaa tacaagtcaa aatggagacg attggcaata
     4621 gcggaacgaa tggcactttg aattctccag cttttggttt gccaaacatt tttctcaact
     4681 tcagtaagcc tagactaaca agcatcaaat aggcgagcgc catgatattc gttagttccg
     4741 ctaatacatt caatgggaaa aatccggcaa agaatacagc tgccacacca gcggcataag
     4801 tcgctttttt cggtgtacga tgcttttgat cgatttctgt cataaactta ggaagtaagc
     4861 catccttgct gacagcaaac agtaaacgag caagtgaata catcatcgag atcgttaccg
     4921 tcagtagcgt taaaattgcc cctacagcga tcaccgcgcc cactgttcca tgtcctacat
     4981 acctcattgc aaaagccact gggtcattga ctcctagttc agtatacgga acgattcctg
     5041 tcaagatcag cgtcacgatg atgtaaagga cagtagcaat cagtatcgaa ccaatgattc
     5101 ctcttggcac atctttttgc gggtttttga cttcctcggc tgccattgca acggcatcaa
     5161 atcccaagaa agcaaaaaac acaagagctg caccatctag cacaccggaa aaaccaaaag
     5221 gcatgaatgg ctgccagtta tcaggtttaa cgaaaaatat tcctacaatg ataaacaacg
     5281 cgatgatacc aaatttgaca tataccatgg cattattcaa acgtaatgct ttcttggctt
     5341 caagcgacac gatgtaagtg acgaatatca ctacgagcac cgcaatcaag tcaatgtatg
     5401 taccattttc cggattgtac ccgccagtta atgcttgtgg aagttcggcc cctaaacttt
     5461 tcaaaaaacc ttgcatatag ccagaccatc cggaagcaac agaggaaacc gctagtaaaa
     5521 attccccgat caacaaccac cctgtcagcc aggcagcaaa ttcaccaaat acaacataca
     5581 gataggcata tggcccacca atcactggca ctcgcgaagc aaattctgcg aaacttagtc
     5641 cagacaaaat gacaacgatt gcagctaaga caaatgaaag tgacagtgct ggaccagcat
     5701 tttgattggc cgcaacccct gtcaccacaa atattcccgt accgatgatc gcaccaattc
     5761 caagcatgat caaatcagac gtttttagtt cttttttcat ctcactcgta tgattgagat
     5821 tgatctcttt cttacgaaac aaatccattg aagttcctcc ccattttagg ttggaaaaca
     5881 gcgattaaac tgttttcata taccctaaaa ggataccacc taaaatgact aaaaggcaac
     5941 caacaataac ataaatgagc tcttttttcg tttttctttc gccaaggatg aaaatcccac
     6001 ctaaagtaga gataatgatc cccatttgtg aaagtgagaa gccaacagct aaaccaagtg
     6061 atttgactgt tagaagcatg cagatgtttc ctaagcccca taataatcca cagatcatgt
     6121 ttttccacac aaactgatcg actttaactt tacggaaagc aaagaagctt gcgcctaaga
     6181 tcattccgat actttgaggt aagataattg acatcgcatc caaattcgcc cagttgacga
     6241 tgatggtata tacaccataa ccaatcgtag agaagatcaa tgctctaaaa cccttaccaa
     6301 aatcaagcat tttattatct gtatctattt ttccttcgtc atcttgtcgg gcagtcaaat
     6361 acgcaccgct tacaagaaga gctaaagcaa taataccgta tacataatct ttcgtttgtg
     6421 tccattcatg gaagaaaacg gctcccgcaa tcgtattcaa aattaattga aaaccagtag
     6481 acaatggtag ccctacagaa acacccatgt acttcattcc atggaactgt ccattttgtc
     6541 caacactcca agctaagccg gataaaaatc cgatcaagaa aatccaaggg gtgattacag
     6601 gactaacaac gaaaaagaca actaaagaaa acagaaatgc accgatcgtc attcctagtg
     6661 tttgttgatt ggcatcgcca ccaattttac cacttactaa accaatacta ccccatgcca
     6721 acatagggac taatgctatt aaaatttcca taaccaatct ccttttattt cacatgataa
     6781 gaaacttatc agcgaaaacg ttaacaacac aagcactttt tttcgtttct aacgattttc
     6841 taacgttttt cattataaaa atttaagatt gggaaaaata aagtcattgt tgtccctttt
     6901 ccttcagttg attcagccgt caaatggata cctaattttt cggccagatt ttttgctaaa
     6961 taaagtccta atcctgttga atgtgttttg ctaagtcgac catttctccc agtaaatccc
     7021 ttatcaaaga tccgtttcaa gtcttccgct gggataccga tccctgaatc tttaactgaa
     7081 aggctgactc cttgcgcttc cttttctatg ctcacaatga tgtttccgtg atccggcgta
     7141 tatttgatgg cattactaag caattggttg aagataaaag cgatccattt agcatcggtc
     7201 aaaacagtat gatcctcacc aacgatctcg tagcgaatat ttttttggat aaaataattt
     7261 gcctgactgc gtatcacagg ctgaatgatt ccttttagtc catattcttg gatgaggtag
     7321 tcccgcgaga aactgtcgag tcttgcataa tacaaaactt gttctacgta ttcatcgatt
     7381 tttgataatt cattttctag taatgtatac ttttgatcgt caatatcgaa ctcgatcgaa
     7441 cgaactagca atttagaagc ggaaagtggc actttgattt catggaccca tgagtcaata
     7501 taatcttttt ggtcttgttg attactgatt gctgattgca ttacttcttg gtgttcacgg
     7561 atcagctgat tgatatattc ttctaccagt ttttcttctt ctgtcctccc accactcaaa
     7621 taattttgca aaggggaagt tttttgtatg tcggctaatt ttccccacca tcttctcttg
     7681 ctcaagtaac cacccagcag ataaaaaatc agaaagacgc cctcaatcaa agctaaataa
     7741 gcaattgtgc tcaaatcaac tttgatgttt ggcgccagcc acatcacaaa gatcgtcaat
     7801 gcaataaaaa acagccatcc caagatcaat gtccactgat ctttcaaata tttaaaaaaa
     7861 ttcatcttaa ccgctcatcc tttcagggaa cgatatatcc ctgtcctact tttgtttcga
     7921 tatatccttg gatacctgcc tgttcgattt ttcggcgtaa ccgattgatg ttgactgtca
     7981 atgtattgtc atctacaaat cgttcgtcat cccacagtgc tcgcagcaat ttttcccgac
     8041 ttaagatctt tccattgtgc ttcatcaaaa taaataatag acgatattca tttttgctca
     8101 aatcaatgat ctctccgttg atttccatac ttccgttgtc aacattcaac gtaatgccat
     8161 tgtggctcat catttcacta gataattctg tgtagttgta agaacggcga agtaatgcat
     8221 tgatttttgc aatcagtaca tcgatttgga aatgttttgt cacaaaatca tctgccccca
     8281 tgttcatagc catgatcata tccatattcg tattcctgct ggagataaaa atgatcggta
     8341 ctttcgatac ttcacgtatt ttttgacacc aataatagcc atccaaaacg ggaagattaa
     8401 tatctagtaa tacaagctgt ggttcttctc tttcaaagtc tgagaacact tgattgaaat
     8461 cggtcgttcc aaaggtttca aattgccatt tctcaagttc ctccatgatc aattgtcgaa
     8521 tgatctcttc gtcttcgact accatgattt ttgccataaa aaatccctcc atctttcttc
     8581 ttgctactac aatatcaaag aagcccttgt gaaacaagtt ggcttacctg gaaaatgtca
     8641 ttttagcaaa cgttaaaaaa aactggaaat atgcgattta atcgcgtttg tctcttccaa
     8701 gcagcttaaa tttattatgt tattcttaat aattggtcta ttatctgtta tttttctttc
     8761 gttgtttttg tcttttaaat tttcgataac accaataacc gaaaagcgtt agcactagca
     8821 atatacctag aaggagtata agtaatcgat aaagatggta tttttttgtc tgttctatct
     8881 ttgaagagac ttcttctgta aagggaactc gtcttcctgt cactagtaat cggtgagtgt
     8941 tcacggtgta aggtgtacaa gtgataagtg tgactagatc ctgcttttct ctaattgcta
     9001 atgtatttgt ttttgttgga aggacaacaa ttttctcaac gacttcataa gcgagcatcc
     9061 gaccatacac ttcaagatag aatcggtcat cttgctccat ttcttcaaga tccgtaaaga
     9121 gttttttctc agcaataccg ctatgggcgg taatcacgga atgtgtactc tctcctccag
     9181 ttggaaaaga ggtgccttgc aggactgtcg ctcctctatc taacaaaaga tcattcgttt
     9241 catcaaataa aggcaagcta acattgattt tcggaatata gatggctccg atcatatgtt
     9301 gttcgtaata ttcttttcct ggattttgga catttctaac cgcttgctca aaaggatctt
     9361 tgacttgtcc cattcctggg attactgatg tatgagcaag cgtctgattt ttcttttcat
     9421 gcactgctaa ttgttgctca tgtttttctt ctttatcgcg ttcaagctgc ttttgataat
     9481 tctcgatcct tctttgatcc aaataattgc tgagagcatc tgctaaaaat ggatatgtaa
     9541 aaactgcagc tccggcaaga aacatcactg ccataaataa ttgtaataaa agactgattt
     9601 gggtttgagg tctattacct attttctttt tcattttctt caccttctta tttaaaaaaa
     9661 ctgcagcaac ctttataaaa ccgattgctg cagcttattt ttgttgctta tacttcagac
     9721 ttcattttag atttacggta ccagctgtac gctccaatca tcaaacttat tccgattagt
     9781 aagaatgcca agagcccgtt cccaccagta gcaggaagtg acccgcgttt catattcggt
     9841 actctttctg gccctggatt ttctactcct acgatctgaa tttcttcatt atagcttcca
     9901 taagagatga taaattcagt aaaggctgcc tcacctgttg gaagtacata accttctggc
     9961 gccatggtct ctttcatttg ataggttcca taatctaacc cttgaacctc aaagtatcca
    10021 tttccatctg cgacaaattc tgttgcttgt ccgcttgttg cccactcaat tctatctgct
    10081 cctgattcat aaacagctaa aggcgactcc cctttataaa atattgcgta ttcagaacgg
    10141 tcttcattcc acaattcgaa tcttgcatct ttaagcaatt cactgcttga tgcatcatat
    10201 ttttcaaact ttcttccacc tgttgtgact ttctctggcg gctctactcc ttcttcataa
    10261 tcaaattcat catttcgtcc gatttcaata accgctgtgt tgttatggaa atcatccgct
    10321 tctagttctg tggaaacctt caaattatac gtgatcgtta aatctcctcc acgtgcatct
    10381 gctaatctac ctaaagtatc tactttggct actccatttt cttctgtcaa aatcgtcacg
    10441 acaaacccgt tgcttactac ttctactata taatcttgtc cttttgttaa aatcgtctcg
    10501 ccggctcgca cttctatttc ctgatcataa taagttagac caactgtagg cgtatctgtg
    10561 attttgtaat ttttgataac agcgcttccg ttttcaagga cagaatcgat gaaataagga
    10621 ataggtgctg tgatcgtgta agaagccgtt tttcctcttt ctagatcaat ataagaaatc
    10681 gtttcttgtt ctccagcttc attaataatc gttacttgtc taaggtcgct ttcctctaca
    10741 ttcatctgtt tatctgcttc tctgatttcg tttttcggat acaaatgcac atctgtattg
    10801 tatgtgtctt tccatgtaga accatcccac acgccatcca ccatatcagg catcatcact
    10861 ggcatcataa caaccattgg agacgcgatt ctggaaatat gagctggcga ataagtttct
    10921 aagaaaagat agactttatc tctagaagaa ggtgcttctt ccgtcacttg gacggtagag
    10981 aataccgctt ctccagcttc attcgttgtt tgtttgtcaa tacttgtcag tcgatatttt
    11041 aaaaaccaac tttctgtgtg ccgtttttga atccattcaa tcgcttcggc agaattaaga
    11101 ccgtcttctc gttccggtgt taaaggatta tctcgaatca aatcgtaata tacttccgtt
    11161 acgtcaaaca aatcaaaatc gactcctgga atattttctt caccaaaatc cgtagaaacc
    11221 aatccgctat tcggtcgttc ttccggaaca gatgagaaac cttttttgtg taatgtaatc
    11281 gtcacttcac ttggtttttg tgcgacttct tcggctttga ctagttttcc gttcccgaaa
    11341 atccctattc ccgcagtaac gagtaacagt acactcattc ccgtgacaat cattttttta
    11401 ttcatttttt tctccccgtt ctttttttat taataaaaca gcacctaaca ataaaagaat
    11461 tcctagtaaa gaaatcaacg ttcttgcttc attcgtttgc gggaatacgg accattttcc
    11521 tgattgacct ggattgcttg gaccactcgg ctctttcggt ttgtccgttg tttcttttac
    11581 ggtctcgtta taaacacgtg gtgttgcgga ttcataggca gagactggaa ctttcccgga
    11641 ttctaattca gccatctcct gtccgttaac tactacatat tgtggttggc cttttgcatc
    11701 cacccaaaat tcagggatga tgacctcgat tctcttactt gcttcatcca tctcgtaacc
    11761 ttccacacct tttaattctt caaaataata ggtgccagaa ggcaagaaac gttgtcctgt
    11821 cgtaacaagg ccctctttat ccgaaatgaa tttgcttaca tttttgtcat tcaaaggatc
    11881 attgtctgct ggtttgatcc attgattttt caagtcatta gcaggagcca tatctaaata
    11941 atatttcccc ccttctatca tctgatatag agcaaaaaca gcaccttcta atggttttcc
    12001 tttttcagtt gttcctcttt gacgtccata cttgaagaag tatggatctc ttagataacc
    12061 gacattttta ggatagatat gaatctcttg cagttcctcg gttgattctg tcgggtgata
    12121 aattggcaaa atagcagcaa ttgggatagc tgtctgatcg atatcaacat ccaatccaac
    12181 ttctggatca atcgattctt cgaaaatcaa ataaactgca tcccgatctt ggtttttctt
    12241 aggtgctttg atacgtgcaa tcccgtctcc taatccgcca accgtatctt tcccagttgt
    12301 taccgaagtc cctatttgga caagcctttc ttctgtgatt agctgacgga tattgtttct
    12361 gttcgtttca gcgatttgct ggacgaattc tttaggagtc atgttttcag cagctttttt
    12421 ttcatgataa taatcggtca tgtcgtaaat ggcaaatgtc gctccattta gtggcaccgt
    12481 ctgtgaaatg atatctgctg tttcccctgc ttcctcagag atagccaagc catcattttc
    12541 atggtattca aattgatcgt tataatcgat atctcgaatc atccgtttat gcaacacgaa
    12601 ttccacgaca tcttcccctg attcttctgc cgacatcgca tgtggaagaa ggactgctgc
    12661 aagcggtagt aaaacaagta attgaagcat caaacacaac agctttttca ttaccttgct
    12721 ccctcctttt tagattgtct gacaaacaaa ccataggctg ctcctgcaag cgccatgaag
    12781 aatgcagcaa gcaggatata gaataatcgt ccggatcctc ctgtagcagg caacggattt
    12841 tcaggatcgt tcccgacact aagctgtaat ctgattcgat ttgtctccaa aagttcatat
    12901 tctaactctt gctgtagatc aggcgtctct gcttcttcgt ttggataata cgaaatctca
    12961 acttttagtg tacccgcttc ttttcctgga actacccgat cattttctat gtcaggttct
    13021 tctcgataac taatttctaa aataaagtaa cctggaagtt ttctatagct gtcaggtgac
    13081 ttcacttcct tgatccgata gaccccttcc aacaagtctg aagcattgaa tagggaagaa
    13141 tcgtttggat ctggtgccaa gcctccctcg atgatttcat actctcctgc actattttgt
    13201 ttctcaattg aaaattctgc gccttcaaga cgtcggctat tcatactgtc aattttcaaa
    13261 agttccaaat cgattggcgc tagttcatct tctaaggtta cttgtagtac accatcgatg
    13321 atttcatagc cttccggcaa gggagcagtt tcgtcttcga tgaccgtatc ttcaatgata
    13381 aacttacctt cttcattcag tgcaaactgg aacacttgat cagatagccg atacccattt
    13441 ggtgcgacag attccgagac ctcatattca ccaatagaca gatgcagagg ttggtcgtaa
    13501 tttaaatcga catacttttc tactcctacg gcacgagaat agaagtatcc gatcccaggc
    13561 aaacgtttcg attcttctgg ttctaacgga ttaccagtgt atgctcgata cagcgggaag
    13621 gaagaatccc ccactttcct gatatcgaaa cctgcaccat ctaatgtatg gccttcatgg
    13681 tctaattttc taactcggat ctcccgataa tcaaacgtat tgtaagcagt gaatgctacc
    13741 cataaacgat cctcttcatc tgttgtatac gtgagatatt gccaattttc ttcacctgtt
    13801 tgcttgagtt ggatagtccc tatagcatta tcgtaaagtc gcaagatcca tgtgtcattt
    13861 tcatcaggtt ctttgaaacc ttctgggttc tggctctcaa tgattttgta ttctgcatag
    13921 ttggtagttt cttcactatc cttataaaca aatgaatctg gctctccgat tggatgaata
    13981 actttctcac catccacgat tacatatttc ccgtcttcat ctactgaata gaacgtgagt
    14041 ctccctttct cttcctctac ttcgttcaca ccagaaagcc ctttcgctac tggatatccg
    14101 atttccagtc cgttaccatc tgtttcataa agttcaaact ctgcgccatt gattggcata
    14161 ttactgcctt caattagttt attgatattc atgtggattg gcttgaattc atttcgcatt
    14221 tccagtttga catacaactc atcatactct gtgccttcta tgttaggctc ttgtacaaca
    14281 gaaagcttgt gatattctcc ttcataatag gaattcggat ctttaccttc cggtccgccg
    14341 actctcgaac cagatgtata ttcatctaca agctcgtagt gacctaacat ctcatcttcg
    14401 ttggctgcat attttttgat ttggaattga tacgtctcat ctactaactg ataacgtggt
    14461 ggtccagcga tctctctgat ccaaaatatg tcgctgactg ctccagtttc atctcctaaa
    14521 atcggcatct tcgtttcaaa gatcgctatt ccgtccgtgg tagttttact tgtttcgatt
    14581 ggttcggctt ccccactctc tggattttgg tcatataatg caaattcgac tccagccaac
    14641 ggctcgccat tttgaccctt cttgctgact tggaaattac ggcctttatg ttcgtaacga
    14701 atggaagaag atgggaaata catccgtcca gtagtgatat cattctcata atcctccagg
    14761 ttctgaatat aggccatatt gttcactgtg caaaaatttc cgtcttgagc tcccgcatca
    14821 agttttactt ggtacttgat cctgaccatt tccccttcac ctaaagaaat cggagaaaat
    14881 ttataagctt ggttttcccg tccgacatac gttgtcggag tcgccactac ttctggtggg
    14941 gcttgtccat gacgttcttc atcccatatt tctggctctt ggtacttcat gccgttttct
    15001 cctggatcta gatggtaaaa ctgaatatct gccgatctgc cagctccaaa tggtgagaca
    15061 ttaaaaccag tttcatcata aagtgtggct tgctggatcg ttctcttgaa ggtagaagag
    15121 atatcctcca aggctgtaac aatgtcattc ttgttgttcg cattgtaata tcgcggtgtt
    15181 acgccatctt cttctaaatc agcaatattt ttcaatacat ttcgtccaat agcatctagt
    15241 cgttgtctcc cgctaacgtt tccatcgatt cctaaaccaa tggagaagat acttggcggg
    15301 ttctcttgat acttgttttt cagccaatga tgataagcaa ctgtgttgat cgcagatgac
    15361 ttttcttgcg aagtaggact gccattcgta ttgttattag aagaaccatc accaacccag
    15421 tgagtcgctt tattatctcc ttcttttacc tctccataac gatagtgtac atttacttca
    15481 tcttctggac ggttaaagtc agatgcatag gtaactggat gagtaaaccc tgcattagaa
    15541 gtattcccag aaaactcctc aaaatttctg aacaaaacgt cattatcttc agcaatctta
    15601 tcttccatca cagtccagtt gctccaagct ccattagtgc tcgtacgata acttgactga
    15661 atcggtgcat aactgaaggt cggtgtccca tctcccacaa cgattaggat tttttctgga
    15721 tttctatttt ctccgccatt gtctttatac aatgtttcat agccattttt aagccctagt
    15781 gtaagcggag ttcctccgat tggtgtacga tttaatgctg tattctcact tcccgtcaaa
    15841 cgattgatat catttgtcaa tggaaagatg tccgaactga tttgctcatg gttattgata
    15901 gctgtactat tatggtaaaa attcaccata ccgattcgaa tatccagact cgggtcagag
    15961 agcagatctt tactcatttc gtttactgcc tcaatcaacg cagcattttt agtttgacta
    16021 ttggtcccag cggttaattc actcatactc gctgacttat ctagaacaaa aacgatatcg
    16081 attggactga tttccttttt ctcgcccccg atgacatcta gatagacatt gtaaagggtt
    16141 gttgcatctt caggatgtag atcagatgct gtgctgcttg gcagaacagg ttctacccat
    16201 tttttgatgt acgccccgtt ataatccaag taactgtttt caaaattccg ttcatttccc
    16261 caaagctgaa cggtttgagc tggaacgttt ctatcttctt cgcctgcagt tgatccatta
    16321 ttagtagcat agtcgtaatt tcgccagttc gctcccccgt ttgtataatc actatcatcg
    16381 atcaagttct ctccgtcata tggcgagcct ttgtctcctt gatagcgttc attgctttgt
    16441 gtccaatttc ctaacacttt tgtatagtca ttcgttgtaa acttcgggta gcgatgctgt
    16501 tcgttttcaa cttctccgct aggatagata tattcatagg ggtcttgcgt agctgttggc
    16561 ccaagacgct ccaaaatacc gttgaataac tggcgttgaa tgcgctggag tgcttgaccg
    16621 ctgggtacga ttggttcgtc cagcttttcc atctcatttt cttcgctacg ttgaatttca
    16681 gcggaatctt ctgtatcagt ttcattttct tgtaattctt ggttatctat tctttcatca
    16741 accaccactt gaagaggtag ttacccttcg ttcacatcgg ggatcttttc tgtttcaaaa
    16801 atcaatgtgc cggtttctgc ttcttttgaa taaacttttc cgacatacca ttcttgacca
    16861 tcgatcgtct cgacttttag gtcttctcca tcttcatcat aggaggatag acctgttcca
    16921 cgaacgtttt ttacggtacc aatcccggcg gctgccgcat cgattgctaa acgtattcta
    16981 ccttcattgg cactttcctt tttttcaaaa gccagatgcc attcaagggt ttcttctttt
    17041 tcaatatact tcccttcaat ttttgcatag tcctcatcta agaatacctc atcctccttt
    17101 gtttctgttg actcagcagc tacatccagg gtcgtcatat gatagactga ctggaaatat
    17161 ggtccaaata gcaaactgac agttactaac tgcaaaagct tcaattttaa ccctttcaca
    17221 tccttatact cctttcaaaa atatttgtct tctttcacaa caatcaacaa aacaatgccc
    17281 atctaattat aatttaattt aattttaatt ttaaatcaaa tgatatcctt tttagttaaa
    17341 aaacaccaat tatacaacat ttattattaa aattaaatta taaaatttta taacgttctc
    17401 atttaacaaa acttaagtta ttaagacaaa tgaataaaca actacgcttt cctcgaaaca
    17461 aaaaaataaa gcacaaatgc gcatttacgc actcatgctt tattcgtaca attaattcag
    17521 ataacggcag cgcataggat gccaataaca cttcctaaaa tagctcctcc taaaatgtca
    17581 gtaggataat gtaaaagtaa aaaaatcctc gaataagcga tcaaacaagc aaataaaaag
    17641 gctaatattc ctgcaactgg acttaattcg aacaacgcag ctactgataa aaaggctagc
    17701 gctgtatgtc ctgaaggaaa agaagaagtc ttcggtttac ttgtgtaaag gacaagccga
    17761 cgattttttt cataaggtct tttccgtctt gtcgtttttt tgataaaaag caaaccaaca
    17821 aaaaaataga tcaaactgcc gataagaatg gctagaccat attctctagt atcaggtatc
    17881 aagactaaaa cagcagcaag gagcaaccaa ataaaaccac cattagagat attactgata
    17941 aatttcaaaa aattgatttt tcgactatcc gttttccgtt gcttggcgaa cttgttgata
    18001 atactatcat cgattttagc aatcaaacgc aacatgttat tcctcctttt taagaacctt
    18061 ttcttgcgta cgatggataa aaagcaggac ttgaaaataa aacaagaaac tgaaacctaa
    18121 taaagcaaaa tagattggtc ctgcaaacca gaatgcgaca agaaggatca acgtgcctgc
    18181 caaatagaaa agcgcgcttt tgaaatcatt aaaaaacaag aaaaatgcag taatccaaga
    18241 agcttctttt tgttccagtt gaagcaagat tttgtaacta aagagaagcg cgcttaatag
    18301 aagcaaaaac aacgtagtat acatcaatgt atagccaatt cccccacccc aatagcggaa
    18361 aatctgataa tcgatcaata gaagaagaaa ataaacactt gctaaactat cttgctttcc
    18421 ataaagagag aagttctcac gaaacttttt ccagaatagt gaaccgagct ttttctcttc
    18481 attttttttg taatgataaa tcatatacag aactgttcga cttgcagttc ctaatgtgaa
    18541 aacaggcaag acgcacagga accatagtag ctgtaaatgg ataagacgtg gaatccattc
    18601 aatgatttct aagaaataat cattggcttt tttaccaatc gatcgattca tcatcctttt
    18661 gaacctcctg tcaaatccat cccttcaatg aaataacgtt gtgcaaaaaa gaacagcaaa
    18721 atcgtcggga tcaagacaag tgttgctcct gccatcagat aattccattg tgtcgttgct
    18781 tggttctgaa aaacttgcaa gccaatctgt aacgtgtatt tttcttgatc ttggatatat
    18841 aacagaggac ctaagaaatc attccaagct gcgttgaagg aattgatcgc aatggtaatc
    18901 aaggcaggtt tcgtcaatgg aagcatcaaa tgactccaaa tatacaaatg attcgctccg
    18961 tcgatttcag cagcttcgat caattcatta ttgatcgata agtaaaattg acgcatcaga
    19021 aatatattga acgcattgcc gaagaacgat ggaacgatca ggggcaaata agtacctacc
    19081 cagccgatct tggagaataa tacatattga gggatcatcg ttacaaaccc cgggatcatc
    19141 atcgtagaaa gaaccaaagc aaacatcagc tttttcccag gaaaatcaag cttcgcaaat
    19201 ccataagcaa taaaagaatt tgaaaggaca ttaccgatca ctactagcac agtgatgaat
    19261 aatgtatttc ttgcatagcg ccaaaaagga aaggcggcaa tcgtatccag atagttttcc
    19321 catacgattt tttctgggaa aaaggtcgga ggataacgaa cgatttcttc cattggtttc
    19381 aatgaagtaa acaccatcca aagcaatgga atgatcaaaa tgattcctat tactgtcatg
    19441 aggacataac ttagtatttt ttttgtttgc cgattcacac tggtcttttt gaaataatcc
    19501 atcatttgcc gtcacctcca gaataataga cccacttagg tgcaagcttc aaattgacaa
    19561 acgtcagaac caacacgatc agaaacagga tcattgacat agccatcgca taacccatat
    19621 caaaagctac gaacgccttg ttccacatat gcagattata aaaaagcaaa gaatttgcag
    19681 gtccgcctgt tccatttttc gtcatgacat aagcttcttg aaaaatttgg aaagaaccga
    19741 tcgtagaggt gatcacatcg taaaaaataa taggagtgat taatggcaaa gtaatacttt
    19801 tgaactttcc ccaaacgcct gctccatcga tttctgctga ttcatataaa gatctaggaa
    19861 cattttgtaa tgtagctaag taaagtagca ttgctcctcc agaactccat attttcatca
    19921 aaatcaacgc aggtttcgtc cattgtggat caaacagcca agctggtcca gggatatgga
    19981 accagcccag aaatgtgttg atcaatcctg cagatggaga aagcagctgc atccataaga
    20041 tgtagactgc tactcctgat aagactgccg gtaaatagaa agctgtacgg aatacactga
    20101 ttcctttgat tttttgattg agtactgtgg ctaaaaacac actgaaaatc gtcgtcagcg
    20161 gtacattgaa gatgacgaaa taaacggtgt tgtataacga tttccaaaat aaatcatcgt
    20221 gaacgaacat tcttttgaaa tttgctagac caatgaaatt catcttggat gtcaaattat
    20281 aatcggtgaa actaccaata actgaaaaaa gcataggccc tagcataaat accaagaacc
    20341 cgataataaa aggcgagata aataaatagg cccatcttgc ttcttttttc tttcggatag
    20401 ataaacgctt caaattttct tgcctcctct gtacctagac agtcaaaaat ggattattga
    20461 ttttgcttga ctaagttttc tactgctttt tgtgcatctg ccaatccttc ttttggtgat
    20521 tttgttccta aaagaatctg gtcaatctgt tcattcacta atgtcgtgta atccggagca
    20581 tctaaaggaa ctggtgtgat caccgtattt ttaaagtttt cgtccgccat ttgatagatc
    20641 atttttcctt tatccgttag gttgtcatta ttcactaaat tctcattggc tgtcttgctc
    20701 gccatgatat caaaactttt ttcgccgaat ttttcttgta cttctggaga agaaagatat
    20761 ttgatgaatt cataagaggc ctcaggatct tttgctccgt atggtacttc caagacgaat
    20821 ccgccacccc acgaccaatg gcctgaacct tcttcttttt ctgggagctg catcacgcca
    20881 aaatcaaaat catccggtgc attttccatc aaactagagt aataattgat attttgggca
    20941 cgcatggcta ctaatccgga aataaatgga tcagatacac cagacccaaa ttcggcttct
    21001 aatttattga tcgtattttt cccataataa tcttgccagt cttggatcca ctccaaggct
    21061 tccactttat ttttagtatc aatcttgact ttttcatctt tgtcaaacca actagtcccg
    21121 ttatctgcgt ttagcgccca tacatcagcc cctaaattcc ataatggata aaaaccgatg
    21181 cgtgtaaatt cttttccttc ttttttatct agtttacgtg ctgtttcttc taattcatcc
    21241 caagttgtcg gtagatcttg ttcactgatt ccagcttctt taaataactt tttattataa
    21301 aaaatgactt gtgtatctgt attgaatggg atcgcataag gatcaccttc atattctact
    21361 gtatcccaaa gctgcggata aaaatcctta gaagtgtctt tttctacata tttggagaga
    21421 ttagttgctt gctgtgcttc tgctctttgg gcaacggaat ttatgtcctg tacaataaca
    21481 tcgggtgcat ttccagctgt tattgcagat aaagatttag tccagatgtc accccatggc
    21541 tgatacttat aatttacatg gatctcgttt tgtgattgat tgaaatcctc aatgatttct
    21601 tcgatagctt cttttcgtgc accggatccc caaaaggacc agaaatcaat attttttctt
    21661 ccatcacttg ttttttcaga agaatttgct gcacttgaac tggcatcgct tgcattactt
    21721 gatccgcatc ctcctaataa aaacaatgct gaacttgcca gcaaccctgt aaacaataat
    21781 tttttcatat tttacctcca aattttaatg taaccgatgc cggttttaat ataacgatat
    21841 cattttgttc tgaaaataac aatttataag gtatgattct aaaaaaatta ttaatgatac
    21901 caatacttta tataattcgc gagcgctttc tttgaatttt ttaatctttc gtagcagaat
    21961 gagaatgtat taaaaataga ttaggaggaa ttttgatgtt tagacaccag aaagaattgc
    22021 agtttgaagc aaaaccagat cgtccgaatc cattaatcgc gaaatatctg caggagctga
    22081 tcggcggcca atatggcgag atgagtgtag ctatgcagta cctgttccaa ggctggagct
    22141 gccgaggaga agaaaaatat aaagatatgc tgatggacat tgcaacagaa gaaatcggcc
    22201 acgtggaaat gttggcgaca atggttgctc gtttattaga gggtgcgcct gttgaagatc
    22261 aagaagcagc gatgcaaaaa gatccaacaa tcggtgccat tatctctgga atgaatccac
    22321 agcacgcgat cgtagctggc ttaggacctc gtcctgctga cagcgtgggc aatccatgga
    22381 gcggtgccta tatcattgcg agtggcaact tgttagcaga ctttagagct aatttaaatg
    22441 ccgaatcaca aggaagactt caagtagcac gtatttacga aatgatcgat gatcgtggcg
    22501 taaaagatat gctgtctgtt ctccttgcaa gagatagcta tcatcaaaat ctatgggaat
    22561 gtgcagtgaa agaattagaa gaaaaagaag gttcaatctt agtcccaagt actttcccgc
    22621 gtgacaaaga acgaaaagac attgcttatg acttctataa cttctcagag ggagaccaaa
    22681 gtagtgaagg ttcttgggct agtggcaaag cactggatgg cgaaggcgaa tatcaatggt
    22741 tgaaagaacc taagatcgaa ggcgctgcac caaaattaga accagtaaca ccaaaaatgt
    22801 atgggacacc tccattcaag aaataaatat ctacccgtag aaacacccgt tttttgttcc
    22861 acacgctttg tgagcaaaac tgactaaagt cattaatcat aaccaccctt caaaagggtg
    22921 gttttctcta gagctataag ctcaaatcac cggccagcgc ctaaagacgc tggctttcat
    22981 attttatgtt caagccatat tgcctttgcc agttttgccc acctcttaaa aggtttatgt
    23041 actactcctt agcccttaaa aggatcgtct tactctcgta cactcagctt atctaacgca
    23101 ctatcatgtt tttcttgttc ttgaatgtac tttttgatgg tcgcttcatt ttgtcctact
    23161 tttgtcacat agtatccttc cacccaaaag tgtcgatacc caaatttata ttttagattt
    23221 gcacaatctc ttgatgatct cctgaatatt ggctcgatat tgattataaa ttatttttct
    23281 tctatacttt ggtgtgaata caatgtggta tttacacatc tactttgtac gggctaaact
    23341 atttcccttt attgctccac ccgcatagca agtggttttg tatttcaatc gctcggcgcg
    23401 ctcaattagg tctaaagaca ataaatctaa aaacccgctg cttcactgac agaaacaacg
    23461 ggttttcaga aaaaaatgaa atgaaaaaga tctcttacgg caatctattt tatttttttg
    23521 attttttata aatggaaaat gcttcaagaa gtccaagaaa taaagccgta taaaaacaag
    23581 aacctatgaa atctttattt attagatatt caacagaaat cccgataaca ctagccaaca
    23641 atatatttat cagaagtgta aaataaggat gctttttata gaatagaact agtgttgttt
    23701 tcatagactc tcctttcttc atatttccaa ttaatcacaa attcacggca ttactagaaa
    23761 aattaaaggg gcgcagaagt ggaaaaatac tcttcgactt tccctacaaa ccaggccatc
    23821 ttgtgtttaa taactatacc aaatctaagg tacctctaaa tctaaattcc atttgtggcg
    23881 gtgacctcca atttttaact cttctatctc ccatccagta tacataacct tgatacttcg
    23941 accacttata tatcgaacac acaaatacct atccattgca ggagtactac ctaacttagt
    24001 tgctacttgc atctaaataa cagctgaaaa gataggactt actcttagta aagtatctga
    24061 actattaatt tttaaactat catttttatc ctcaactaca tgcacatctg ttgcaacttc
    24121 actttctgtc tcatccagat aaatgattaa ggaatcggga attgcaatat cttcagctga
    24181 cgctggaata gttgagctaa attagtcatc atatctttat tataaaataa ccaacagcaa
    24241 aaaatacaat gaaaaacaaa cttggaacta atgtatcatt aataaatgtt gaaaaattca
    24301 gcaactcatt actgtatgat tttagcagcc caaccaacat ataccctata aaagctaata
    24361 agatggttag gaatccttta gaatttttac tcattcatag acacttcctt aaataacttt
    24421 tattatagaa ggtattgtaa ataataatat tgacaaaaag tgactcaaaa taaaaaaaac
    24481 cttacattat actggaatga actgtattga tagtgtacct aaaagctcta ctgacataag
    24541 atcgtgtaat cggtaaagta attttattaa ttatacggga tgtaatcaat tagagaataa
    24601 actaatcata aaaggtactt ttacattcat aattgtcgct ttgagattct actttggttc
    24661 actatctgac ccaattgcac attttcgatc attacaagta ttggtgtcgt tagaacaact
    24721 aaataaaaac tagcggtaga tttttcagaa tctatgctaa tttctgtatg gatgttccag
    24781 tgatggcaaa tttctctttt cattgttttt cttgtcgcat gatatgcctt tttgtgttat
    24841 tcagttaaac tatagaaatt ctttcctaga cagatcttga tcccaaattt tacgtttttg
    24901 agcatcgata tagtttaaaa tgacattact catatctaaa gagtttagat tttttaggac
    24961 taaaactgtc agttgttctt tttcttcttt ctgttaaagt attgtcgcga cttttcgtat
    25021 acgttaagat atgtcgtgaa aaaacaagtt ttgtgacaca aaaaaacgaa tgacttgagg
    25081 aaatcacctc aatcattcgt ttaaaatgct atatattctt tagtttaaga tacggaaatt
    25141 aatgccatcg accacactag tagaatgaac gacatttact tggccttttt ttaatttcgt
    25201 tatgtttagc atataaaaat attatagagt ttacttacaa tgcttaaaac atatactgta
    25261 taatctgatc aattttagcc atgtcttgca atggtaagtt ttctattttt ttgagttttc
    25321 gttccttaaa atcaagagat tttaattgtg taataattac ttgtcctttt atatctagct
    25381 cttcaggtaa tgagtaacgt gtcggtaaat tctttatagt ggaagtaatt ggacatatga
    25441 ccgaaaacat tgttttacgg ttaaattcat aacgagagac gactagtcct ggtcgtcttt
    25501 tttgaatttc ttttcctacg gagggatcaa aatcaatcca tacaatatca ccttttttag
    25561 gaatataaat tctttcttct gacactataa aatttctctc ccttcaggag ttaaatcttc
    25621 ccattcgtct ttctcataat actcggcctc ttccccacca ctaaatggat cttcaatttt
    25681 tggaactaac gtaattgttc catcatcaga atacacaacg atatattctt ggttttctga
    25741 aggtttcttt ccgttatcag aaggtaaagt taccactaca gaacttcctt gtaatctaga
    25801 ttttgtaaca agcattatca tcactccctt aataaaagta tactatataa cactaagtaa
    25861 cgcaaaattc ccctttgtaa actatctaga aaattgtttt gtttaaagta tatcttattg
    25921 gatataaata gaaataaatt gtagccagtt cattttttct ttaactaaaa aaataatcca
    25981 agaaacattg aacctatgga tccaaaagct acccaaatac tatagctaac cccccgctac
    26041 cttcaatttt gcagataaaa cgctttggga gaaaatttca aagacaacag gccatcctat
    26101 catgcccgat tataaacaaa aagctggcta ttccttttgc tctgacaaat ttcaattggg
    26161 aaagttcacg aaactagcag gtgaagaagt ttcaactgtt cggatcaaag aatgcccgct
    26221 tcaaatagaa acattggttc aacgaatttc aactagacaa gactttgcta ttgtagaacg
    26281 tgagatcgta gctatttttg tagaagaagg gattttacat gatccaactc atatcaatgt
    26341 ggataaatgg caacctctta tctataaatt cagagaatat acaactgcca accagtcgtt
    26401 aactttgaat tttagattcc aagaattcaa agagtcataa tgataaacat cgttaggtat
    26461 aaataaaaaa gactcgcagc acgagtaaaa aacaaataga agctatacat tagaaaggtc
    26521 gactgtgacc ctatagatgc agtatatgca gcttatgagc atttcttctg ttctctttgt
    26581 ttttgggatc tgtgctgaag tctttttcgt tttttgccgc tctttctttg aaaaatcgat
    26641 tatgttatac cttctccatt actaattcag gcatctgctg agtaatgatt tttcgcgcaa
    26701 aagaaatatc tgttacccaa ggttcgattt gttcttcagt caagacaagc ggcattcggt
    26761 catggattgg tgcgactgtg cggttaggtt cagtagtcat tatgattgat tctgccattt
    26821 tttcatcctg atggctacga taaaaaccgc caatatacac tattttttcc ttatttgaaa
    26881 acataaattt gtctttttct tcattccact cattgggaaa acacaacgat tttgcaaaaa
    26941 tggttgatga aaggtctttt tttcttctac tgtctctgca cgggcattaa tcatcaattg
    27001 tcctttttta aatccggtaa atccccactt catgatttcc ggagtgagga tgttttcttc
    27061 ctcttttctt aacgtcacaa caagatttga cggaaaaact tctccagctg ctaattctgc
    27121 tgcctgcttc ggttgtttcg tctgggcttc tcgataataa ttctgaagga gctctgactc
    27181 tagatcaaaa aaataacgac cacacatcct aatccctccc aatctttttt tctatcatac
    27241 actgcaacaa gaagttcgca ccaacaaaac gctttcaatt tttgtagaac taaaaaagtt
    27301 gtgacaagtg acaaactctc cagtgaatgg tattctcctg ccaactcctc ggtcacaagt
    27361 cacaatattc aacaaacatg agaagctgct ttttgaaatt gttccttgtg actcggagtg
    27421 aaacggcagg cttacgacct ctgggtaaac ggtgttcaaa agccagtttc tcggtattaa
    27481 gccaaattta tgcaaaaatg tagaaagcta ttttcacaaa atttttctta atactcgaaa
    27541 ctaagcgact ttttcacaac ctcttcctta aacggtgttc aaaagcttgc atctgcggta
    27601 ataagcccaa ccaaacgaaa aatatgagca gctattttta tttggctgtt cttattactt
    27661 gatgcagggc agctttttca caacctctcc actaaacggt gttcaatcag ctaaccttcg
    27721 gtattagctc aaaaaacggc aaaatatgag gaactatttt gccgtttgtt tctctaatac
    27781 tcaggtcaaa gcgctgattt cacaacctct aatacacggt gttccagaag tagcttcttc
    27841 gaaaaataag ccgaaatttc acaaaaattt gagaagcaat tttcgtaaat tccttcttat
    27901 ttcttgaagc tgaccacttc tgtcacaacc tctaattatt aaagaacctt ttgcgaagtt
    27961 aacaatcttt ctttgatcaa ttgaaaattc tgcctaagta gtgatagatc ctgtgtgact
    28021 ttcaacaata agatacttcc ctggatttca gcaatcaacg ctttggcttg acggtctgct
    28081 tcttcatcgg acagtttttc ttcagaaagt gccaggatat tttgtttcgt atacttgacc
    28141 cattgattga ctaattctag tagcaacaga cggtattctt catccactgt actcaactca
    28201 ataatcaaat tacctacagg acagccatga taagtgatct gtgtctcatg atcagcgaaa
    28261 atccagtcca acatttcttc taatgcttct tctggctgtt ttccagcatt taagatgtct
    28321 tcgaacaatt ctgtctgcca tacgtccata tgcgcatgga tcaccgctag acaaacttct
    28381 ttttttgaag aaaagtaata ataaaattga ccttttcctg tatcagaagc tgctagaata
    28441 tctcggattg acgtttcatg atagcctttt ttataaataa gatctttggt cgcttccaag
    28501 atcttttcct ttgttttcaa tgatattctc ctttttcatt tctcatagtc ctatattata
    28561 cagtaaattc atcatttttt cttcttaatc gtttaaaaaa gactgtgcca aattatctga
    28621 cacagccctc actataaaac tgttctcata tagctagatg ttcattgatt caagaactgc
    28681 gaggacaaaa gcaattccta tcttatgata gttgctctaa tacttcctct gttgtcatca
    28741 cttgatctgc aataaagcca aagttcgtca acgctgcatc cattgcttct tggccaggag
    28801 caccaattgc atctgtcgct accacaacat tgaatccact ctctaccaat tcacgcatat
    28861 gggaatcgct acacaagttt ccgttcattc caccaagaat tactgtgtcg attccatttt
    28921 ttctcaattg gagcgccaaa tcattgcttt ctggtccaaa gattttatga ggagagctga
    28981 tgatcgtatt ttcatccaaa taaggtttca attcttcgat aaaatcggct cctgaacctt
    29041 cttccactga ttcatattga ctttttctag caaacatctg ctgctcaagc atcatatgtt
    29101 ctcctgcacc gccaaattgc catttatggt catgtgggta aaaataatga ggagaaataa
    29161 agagtttgta tcctttttct tttgcttgtt ttaccatttc aatcatattt tcgatcgtat
    29221 tgtatttttc taagatatct tttgtcaaac caaagccacc gcctgctggt ttcaagaact
    29281 cgacttgcgg gtcagtgaga actactgctg tatttttatt attgaacatg gtggattctc
    29341 cattcgttat ttattttaat acatcattta gagcttcact cattgtcgga tgagaataga
    29401 tttgatctct caataacgta taaggaagtt ttccattcat agctagcgaa atcaagttga
    29461 tgacttcatg agaatcttcc gcatagatac ttgcccctag aatcaagtca gtttcagggt
    29521 cgactaaaac tttgaataca cctttaggat cttctaatac ttgtgcttta gggacaccgc
    29581 ttgtcatata cttgaataat ttgtaattga cgccttgtgc tttggcttgt ttttctgtta
    29641 aacctacatt ggataaagtc ggagtgataa atacactgta aggcacagct ttccggttat
    29701 tcgttgttcg tttattctcg cccttcaact gatccataat gattcgataa tcatctagag
    29761 agatataagt gaactgcaat ccgcctttga cgtctccaat cgcccaaatg ttgtctgcat
    29821 ctgtacgaag gtattcatcc acagcgattg ctccgcgatc tgttagttta acatctgtat
    29881 tttctaatcc aagtgatgct gtacttggtt ttcttccagt tgcagccaaa acttttgacg
    29941 cttggattgt tacttcttgg ccatcttctg taaaggtgac ggcagctgtt gattcttggt
    30001 ctgctacttg atctacagat acacctagat ggaattcgat tcccgcattt gtcatgtctt
    30061 ctaaaatcat ttgcgcgata tcttcatctt cacgtggaag aaattcagaa tgggcatcaa
    30121 gaacgacaac tttagatccg tattcattga acattgatgc aaattccaag ccaatatatc
    30181 cagccccgat gatcactaat ttttccggta attgttcctg atccatcgct tgcgtagaat
    30241 caatcaagta gcgacttgta ttcaatcctt tgattggtaa aatgattggt tcagaaccag
    30301 tattgatgaa aatccgttcg ccttcaacaa tcactttttc accattattc gtcacttcga
    30361 tttgatggtt agaaagaaaa cgtgctgtac cgtccatcac tgtcccagtt gcctcatcgc
    30421 tgatcatatg ataatttttg gcgcgaagca tgcccgtcaa tttttctttc cgagcaacag
    30481 cctctgtaaa gtcgattcct ctttctccat tgaaaatcaa tgatttagaa ggaatacagc
    30541 cgatgttgat acatgttccg ccatacatac gtgttgactt ttcaacgact aaaaccgatt
    30601 caccttttga agctaacgcc ttcgctaaag tcttaccgcc ctttccaaaa ccgatcacaa
    30661 tattttgata tttttccatc atttttccct cgcttctttt ttacctaccg attggtacaa
    30721 aaatatgata accgataatt gtctattctc caaatcatct gctttatttg tcaaaaaaaa
    30781 ccagacaaaa agcggtcctt tcacgttttt agtctggttc gatttccttt attcttctaa
    30841 acaatcgtta cttctacatc gatatttcct ctagttgctt tggagtaagg gcagaattca
    30901 tgcgcatctt ctgcaatttt ttgggcttct tcttcgctga tgccatcgat atgcacttct
    30961 aatactacac cgatctgata gccgccatca tctaaattat aaagagagac acgtgctttt
    31021 actgtggact ctgctgtcat tcctgcttct ttgatcatat gttgtaccgc cccattgaaa
    31081 caagaagcat aacctgctgc aaataattgt tctggatttg ttccttctgc atggattcct
    31141 ggaggagtga ttttcatatg catcgagcca tttggtgcct cgacttctcc attgcgcccg
    31201 ccatggttga tcattgctgt ttcgtatgct tttttcattg tactgctcct ttcgattgac
    31261 catttgctac ttggctataa ttatagtgta tgacaagtaa ggcgctttct acaaaaattc
    31321 tgcttattcg aataccagaa tgccgtcttc tactattttt ccaaaaaaca aaaaaatact
    31381 actcgtgaac aacagcgtca tatttgttcc aaaataaata gcaatctttt ctacataatc
    31441 ttttatatga ttgattttaa gatacatata taccagaaag ttgaccccat aaaccaatac
    31501 tgttaaaaaa ataaccatat tcgttaccat tttttcctcc ttttgctggt ctccctacca
    31561 gcactcgatt taaccatacc actttttttg ccgtccaagc aactagcctt tcaaaaagac
    31621 tggtttattc tgctgttaat gattcaagat cagaaaaatg tccgaataat tttgctaatt
    31681 ttactaacgc caacttgttc tttccgaatt catcattttc tatctgtaat actagtaacg
    31741 gctcatgtaa gcttaaacgg atcaaaaacc agccgtttcc gtatggctct tctagatcat
    31801 atcgaatacc ttcttcattt tccgggtcga agttcatccc tttttcttct tccaacagtc
    31861 gcttcatttc ttctaatatc ttgtttcctt gttcgcgtgg ttcatcgctg aacaatttta
    31921 atcggatttc ttgtacttct acgggctgtt tcaactcttt gatttgttca tctaatgtga
    31981 taccttttct ttttaattct ggcaaaagca tcaggatctt tgcgatgaca tatgcaccat
    32041 catccagaaa atagttttcc ttgaatgcag cgtgtccgct tgtttcgatg gctagctgtg
    32101 tatctttccc aagacggtta agttctaatg ctttattgat tacatttcga tagccggaaa
    32161 tataacgaac ttggatgcct cctttttctt caatgaatct ttgtagatga gaagaagtag
    32221 gggaattcgt cacgattctt gttcctggat gctcttttaa tacgattgta cttaatactg
    32281 cgatcaaatt atttcgattg atcactgttc cagaagcact gacaactgca gaacgatcca
    32341 catctgtatc gaaaatgatc ccaagatctg cttcatttgc taaaacagcc tgcttgatac
    32401 tttccatcgc ttctttatta tcaggatttg ggatatgatt aggaaatcgg ccatctggtt
    32461 ccaaaaattg ggaacctgtt gaatccgcac ctaagctatt caatactttt tcagcaaaga
    32521 atccaccagc accatttccg gcatcaacaa tgattttcca accatttagt ggtttgcttt
    32581 ctagtgttcc aatccccttt ttaatttttg tgactaaatc ttgcgcataa ggtgtcaaaa
    32641 ggtctgcttt ttctacgctt ccagtttgtt cgctttttat tttttgctgc tgtgatagga
    32701 taaaagcaat atcttctttt tctgctcctc cttctgaggt aaagaatttt attccattat
    32761 aataataggg aagatggcta gcagtcagca taaccgcagc atcgcacgag aactgttcaa
    32821 attgagtgga cataaacata gcaggcgtag tagctaattc gaaatcgatg acatgtatcc
    32881 cttgttcttt cagactttgg atcaacgcct ctttcagtgc tggtccgctt atcctactgt
    32941 catgaccaat cccaatcgtc cattttttat ttggatcggt tgatttcttc tttttcttta
    33001 tccagtttgc tagtccccag ccgatctttt ttaccatgtc tgtcgtcaag tttacttcat
    33061 atccttcaac tggtaatgcg attcctcgaa tatccgatcc attttgcagc gctttcatat
    33121 ctttcatata aaagtcctcc tcatttattc cctcattttt tccagctttt ctgcaaatcg
    33181 ctgtgcttct tcttctgagc ggcaaataat aatgaatgta tctacaccgg ccatcgttcc
    33241 gacaacttca gggtaagcca cttcatctag ccaattcgtt accacatcgg caccatttcg
    33301 ttcagtcaat acgataacca tgaactgaac agactggata cgcaaaacct cgcgtctaat
    33361 tgctgtacgc aaacgttctt catttaaaga aacagatggc tggttaaata atgtatagcg
    33421 tactattttg ttttcatttt gactttttac taacttcatt tctcgaatgt ctcgagaaat
    33481 cgttgcttga gtcacatcgg cgcctgcttc atgcagccgc gcaagcagct cttcctgtgt
    33541 cccaataggt tgttctgtaa tgatctggcg gatcagtgct tgtcgctgtt tctttttcat
    33601 attagacacc tctcaatgtt gattatagca aaagataagt aatatttctt catattttgg
    33661 tattttttac ttttattttt tgttttcatt caggttgcta acctttttct attttaacac
    33721 gcaaaatcgt cttcattttt tcaggtgctg attttcttgg atcgctgatg taaatctctt
    33781 tgtgttcttt agaagctctt tcatagcctt cttttgcgat gaatgcttct aatttctcaa
    33841 acgttgctgg ttcttcggca tagggcccga cgtgtaagat ttgggcacaa agaccttctt
    33901 ccatcttttt gaatactact tgttctttca agtcttccgg aagtttgcta gaacgctgaa
    33961 tggcttcttg tgctatcgct tctgtaacaa agtcaggctg tcggatcatc aattgataag
    34021 aaaaatgttc ttttttcatc actggttcat gcaaatactt ttcttgcagt ccccattgtc
    34081 cttccagtgg atagacagta tacatctgat aatcaggaat cagccaattt tttttaggcg
    34141 acatgcgtat tgcatagctg actgcatata gacaggctac tcttcgttta aagtcttcct
    34201 gattcgggtc gccgatccct ctgatgctaa agaatgattt tttaggaacc tctagtattt
    34261 gcgggctttt tttcatacta tagctcttgt ctttacgcca ttcaattttt tccatttttc
    34321 ttcctccgcg aaattccatt tagttattta ttatcatacc tctttttgag tgacttggct
    34381 aatcgtgttg acactatttt tcagtttgtg ctagaataag tgaagtaaat aaatcgtaca
    34441 gataacacgt ttcggcgtgt cgagagagag gcggtttcta tttttataat agaaatcact
    34501 ctcttttttt acgaaatttt ttagaggtga tgtaaatgac aaaacaaaaa cagctgcttt
    34561 tagtacctgc agtaattgca acagggatga tgtcttttgc gggcgtattg atcgagacgg
    34621 ccatgaatgt aactttccca actcttatca gacagtttga tttaacgact gcacaagtcc
    34681 aatgggtaac aacgatttat cttttgatga tttcgatcat tgttccgctg tctacttatt
    34741 tgaatcgcaa ttttagtctc aaaaaactct ttttagcttc aaatctgctt ttcttggcag
    34801 gtataatgat cgatttcttc tctcctacct tcatggtcct attgtttggt cgattgctcc
    34861 aaggtgcagc gacaggtatc gctcttccgt tgatgttcca tattatcttg acatttgccc
    34921 ccctcaatcg acgaggcgcg atgatgggtg tcggtacttt gacaacggcc attgctccag
    34981 caattggccc cacttatgga ggcattatga cttcacattt tacatggaat catatcttcc
    35041 tgtttcttgt gcccgttttg tttctttctt tgattatcgg ctggtttgct attcccgaga
    35101 tggcagtaca aaaaagtggt tatttggatt ggataagcgt tttaggaatt tgtcttttgt
    35161 ttagtggaag tctaacattt ttgagtacgt tgggaacagt ttccagctgg attgctttaa
    35221 tcatcggcgg tattggctgg ttcctttttt actatcgaag taaaaaagtg gagcatccac
    35281 tgatccgact gtctattctt tcaaataaaa cattccgctt gtttttgatt ggcttcttag
    35341 tttatcagtt tttattactt ggtgtatctt ttgtcttgcc gaatttcctt cagatcgttc
    35401 aaggaagtag tccttttgtc gctggattag cgatgcttcc cggcgcagcg gttggtgctt
    35461 tgctttctcc tttttccggg aaaatgctgg atcaatatgg tccgaagaag ccaatttttg
    35521 ctgggctgat tctttctttg attggttggc tagcattatt cctactcata ggacacgctt
    35581 cagtgggtgt attgattgct tgtcatgtgt tttatatgat cggtatcgga ttatcttaca
    35641 gcaatatgat gaccaccgga atgaatgcac tgaatgaaga actacaagga gacgggaacg
    35701 caatgttcaa taccttgcag cagttttctg gcgctgtggc tacttcatta gtagcggtca
    35761 ttatcaatta cgtccagcat catacttccc ataactatga agtgtctact acattaggat
    35821 caaaagcagc attaggcgtc ttgttgctgt tgcttctcgt aagctttgct cgattcgcct
    35881 attatctgtt ctttgctaaa aaagcgtaga ttccatatac ggcaggtgtt gcatctgccg
    35941 tttttttgtg tgaaaatggt tgtttgtaaa aggaggcttt tttatggaaa aaattgccat
    36001 tatcggtggc gggatcattg gtatgaccct agccagttac ttagatacat caaaattcaa
    36061 tgttgcttta tttgatgaag ggacaggaca ggcaactaaa gctagcgctg ggattatctc
    36121 cccttggttg tcgaaacgca gaaacaaaca atggtatcgt ctggctaaag acggcgctgc
    36181 ttttttccct aaacttataa aagatttcca acttgatcaa acgatttacg cacaatcagg
    36241 gacacttttg cttcgacctg aaaaagattt agctgaattg gctgttcttg ccgagaaacg
    36301 aaaagaagaa gcgccagaaa ttggaaacat cgaatggctt tcacctgaac agacatctca
    36361 agcacttccg ttattgaaac cagcagtttc actgcgtatc agtggtggtg gtcgtctgga
    36421 tggaaaagca tatttagaac atcttggtca gcgtttagca caaaaacaaa tggagcagat
    36481 ccaggcaaaa gtcactttgc ataagaagag cgattcttgg ctcatcaagg gaccgtttgg
    36541 agaatacaca gctgatcgtg taattttgac acctggcccg gcacttaagc ctttattaca
    36601 agaattaggc tatgctgcag atatacgtcc gcaaaaaggg cagctcttag catttcagac
    36661 atcttataag atgagtcaag actggcctgt tgctatgctt gacggagaag ctgatttcat
    36721 tcctttcatg gatggaaaga tccttttagg tgctacccat gaaaacgatc aaggctggga
    36781 tttggctcct actagcgaag cttataaggg attgactaag agtacagaac agttcttgac
    36841 tgatccagat cagataaaaa actggccata cgagttccgt gtaggtaccc gtgcttatac
    36901 gtcagatttt tccccatttt tcggcgtact gccagatgat ccaagcttac tggctgctag
    36961 cggtctaggc tcttctggct tgaccacagg tccttatatc ggctatctat tagccaactt
    37021 cttaaatact ggtcattggc ctacggaaga ttatcaaaag gacatctcca cctatattac
    37081 gaaaaatcca tcatagaaaa acagcttttt caagtaagga tcccgagcga tattgcgcat
    37141 ggattacttc ttgaaaaagc tgttatttta gttcaatttc tgaatcaaat tctccaaact
    37201 ttcttttgct tcatctggca agagatcttt tcctatctga gcttcaatga atcgtaaacg
    37261 aatatcaagt cgttgtttca ccagattttt ataggacgta tcctcaaaag aaacaggaaa
    37321 atctggtata ggtaaatagt ggatgtcttc aaatggacca aacgacttga attctgccgt
    37381 ttgttgcacg attctttcaa cgattgacaa tgtcgtttca ggtttgattt ttttatcatc
    37441 gaaatatcca gtattcagga catagcaggc tgtttgctgt ttcaaaaaca actctcgaaa
    37501 agcttgatag tcttccctaa gaggatagac acggaaagga ttagcaaatg gttcaatgac
    37561 tagctcatct agctgtcttt ttgtagtgat attttccgcg tctgatcgtt ttgttgctaa
    37621 tgttgcacca aaagacgctg ctaaaactgg gtcattgatc ttgataattg gcggaagcga
    37681 atcatctttc atgatccaaa aaacagcatc gatcttttcg ctaagatgat cgactcggtc
    37741 gggtgtcgca taacgtgatt tgactgtccg cccatttccg tttcgtatat ctcctgttac
    37801 taggactttt tctcctttac ttgtacatgt cacgcccaca ttctgacaag taaggaaaga
    37861 agaaatggcc ggatcatcag acggatagtc ttgtgtttta tcaaagtaag aaggttccaa
    37921 ggcagtagca aaaccatttt ttcgagaaat aacgaaagca tcgtcatgca agatcgaaac
    37981 agagtgacct tccgtatgtt ttgctaaggt aatcgttgat tttccagaac cggacaaccc
    38041 aaatacagcc atcgtatagg tctggtcatt actagcatat tgtttcatcc caccgtggca
    38101 ggcaataaag ccattgcgat ttcccaatgc ccaagcaagc gtcaaagtcg ctttttttaa
    38161 ttctccaaag taacgtaatc ctagcacagc cgctgtatta tggagagcat caaacaaaat
    38221 gagtccattt ggaaatgttt catgtgtcca ttcgggatca caaaagatat aaagatctcc
    38281 ctcatcaaag gaaacagact tttgataagt ctctaagatc ttcgaattcg ctggctgaaa
    38341 attcagcaaa taagaataca aattgttctc aaatccttct ggaatcagca aatgactttg
    38401 cacagaaaat tcttcagata ggccaacgat tacttttgta tggtaaaact ggcgcttgcg
    38461 actttgatac acagcttctc ttaaaatttt ctcgtatttg ctttgttcct tgtctaagtc
    38521 ctcaaagatc cgccgagcac ttgctgttct tcccacaatg cttccatcat tgaatactag
    38581 tgtcctaaca tcagctggta aatctagttc ttcagcatgt gagattgtta aatctgtgat
    38641 gatcgttcct ggactccctt ttgctagttg ataagctgtc ttcctatcaa aaacttcatg
    38701 aacattatta ccgtaaaatg tcgtttctac aatcgatcga atactggata acagtggatt
    38761 tccacttgtg atttcgttta attcgagact ctcttttgta ctcatggctc ctcctcattc
    38821 cctaaacaaa aaaacgtttt ctttattata cattattcga gtttttattt gtactgctgc
    38881 gctgtgggaa gcaaacgagt tatttttcac acaaaaaaac cgagaacttg aataaacaag
    38941 tttctcggtt tcatcatttt ccttttatcg gcttagtacc agccgtttgc taaccagaat
    39001 gttttagcag catcccatga accataacga gatgttacat attgttctgc tacacgttct
    39061 tgattggcag ctgaatagtc gccgtttaag tatgaagcat ctaattgata acggccgatg
    39121 taacgtccgt tagtagctgt gtatgaaccg cctgattctt tttgtgcgat ccattctttt
    39181 gcagagcttg aagttggcgc tgttgcagca gctggggcag caggagctac ttcaactgtt
    39241 tcaacaggtg caacgtatgt atgttcttgc gttgctgttt cagttgtaga tgctgtattt
    39301 tctgttgttt tgttttctgt tgttgctgaa gaatcatttg aagttgggat tgttaattgt
    39361 tcaccaacat aaatgcggtt gatgtttgcg atcgaatttt tttcagcaat tgcatcgatc
    39421 attgagttgt ctcctgcaaa tttttgtgag atcttagata atgaatcacc tgattttact
    39481 gtataaactt catcagcgtg agcatttgta gttcctacaa acattgcagt agcaccagca
    39541 gcaaaagttg tacctaaaac aattttctta aatgaattca tattaaactc ctttttttct
    39601 ccgtttttta ttctttcgac gctattaact ttatcattta gaaatatttc ataggtaaaa
    39661 gaaacatgac atttaatgac aaaataacga attatttaat atttgtaaca tttaaacaaa
    39721 tatttttttg atacaaaacc ataaaagcct tgttgtataa gcaaagtaat cgtttttcta
    39781 tgttttttta tttttgaatg aaaaacgcag attctgtaac attcactgca ataatccata
    39841 aaaaaaagca aaaaaatttt tgatttttat caaa
//
LOCUS       DAZUJR010000015        39634 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.015, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000015 DAZUJR010000000
VERSION     DAZUJR010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39634
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.015"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(35..910)
                     /locus_tag="ACG804_000746"
     CDS             complement(35..910)
                     /locus_tag="ACG804_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFS4831695.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            1058..1390
                     /locus_tag="ACG804_000747"
     CDS             1058..1390
                     /locus_tag="ACG804_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HFS4831696.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            1502..2710
                     /locus_tag="ACG804_000748"
     CDS             1502..2710
                     /locus_tag="ACG804_000748"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HFS4831697.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            2864..3319
                     /locus_tag="ACG804_000749"
     CDS             2864..3319
                     /locus_tag="ACG804_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831698.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            3681..3956
                     /locus_tag="ACG804_000750"
     CDS             3681..3956
                     /locus_tag="ACG804_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831699.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            3969..6047
                     /locus_tag="ACG804_000751"
     CDS             3969..6047
                     /locus_tag="ACG804_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFS4831700.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            6210..8093
                     /locus_tag="ACG804_000752"
     CDS             6210..8093
                     /locus_tag="ACG804_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFS4831701.1"
                     /translation="MKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKTS
                     LLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVRA
                     YEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIST
                     LSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDRY
                     FLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMRA
                     GVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRINDQ
                     TLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQE
                     NEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEKR
                     RLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVAD
                     KLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKEW
                     ETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSEW
                     VED"
     gene            8105..9052
                     /locus_tag="ACG804_000753"
     CDS             8105..9052
                     /locus_tag="ACG804_000753"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004799 - thymidylate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006231 - dTMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HFS4831702.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            9072..9599
                     /locus_tag="ACG804_000754"
     CDS             9072..9599
                     /locus_tag="ACG804_000754"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HFS4831703.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(9662..10315)
                     /locus_tag="ACG804_000755"
     CDS             complement(9662..10315)
                     /locus_tag="ACG804_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HFS4831704.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            10447..11289
                     /locus_tag="ACG804_000756"
     CDS             10447..11289
                     /locus_tag="ACG804_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFS4831705.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            11447..12343
                     /locus_tag="ACG804_000757"
     CDS             11447..12343
                     /locus_tag="ACG804_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFS4831706.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            12346..13059
                     /locus_tag="ACG804_000758"
     CDS             12346..13059
                     /locus_tag="ACG804_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HFS4831707.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            13079..13597
                     /gene="msrA"
                     /locus_tag="ACG804_000759"
     CDS             13079..13597
                     /gene="msrA"
                     /locus_tag="ACG804_000759"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFS4831708.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            13594..13821
                     /locus_tag="ACG804_000760"
     CDS             13594..13821
                     /locus_tag="ACG804_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HFS4831709.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            13973..14524
                     /gene="lepB"
                     /locus_tag="ACG804_000761"
     CDS             13973..14524
                     /gene="lepB"
                     /locus_tag="ACG804_000761"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFS4831710.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(14607..15149)
                     /locus_tag="ACG804_000762"
     CDS             complement(14607..15149)
                     /locus_tag="ACG804_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HFS4831711.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(15386..15784)
                     /locus_tag="ACG804_000763"
     CDS             complement(15386..15784)
                     /locus_tag="ACG804_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFS4831712.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            16044..16904
                     /gene="ylqF"
                     /locus_tag="ACG804_000764"
     CDS             16044..16904
                     /gene="ylqF"
                     /locus_tag="ACG804_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HFS4831713.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            16897..17664
                     /locus_tag="ACG804_000765"
     CDS             16897..17664
                     /locus_tag="ACG804_000765"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HFS4831714.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            17720..18577
                     /gene="dprA"
                     /locus_tag="ACG804_000766"
     CDS             17720..18577
                     /gene="dprA"
                     /locus_tag="ACG804_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HFS4831715.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            18699..20777
                     /gene="topA"
                     /locus_tag="ACG804_000767"
     CDS             18699..20777
                     /gene="topA"
                     /locus_tag="ACG804_000767"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HFS4831716.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            20746..22122
                     /gene="trmFO"
                     /locus_tag="ACG804_000768"
     CDS             20746..22122
                     /gene="trmFO"
                     /locus_tag="ACG804_000768"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0047151 - tRNA
                     (uracil(54)-C5)-methyltransferase activity,
                     5,10-methylenetetrahydrofolate-dependent [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HFS4831717.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            22320..23225
                     /gene="xerC"
                     /locus_tag="ACG804_000769"
     CDS             22320..23225
                     /gene="xerC"
                     /locus_tag="ACG804_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HFS4831718.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            23262..23810
                     /gene="hslV"
                     /locus_tag="ACG804_000770"
     CDS             23262..23810
                     /gene="hslV"
                     /locus_tag="ACG804_000770"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0004298 - threonine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HslVU peptidase proteolytic subunit"
                     /protein_id="HFS4831719.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            23824..25224
                     /gene="hslU"
                     /locus_tag="ACG804_000771"
     CDS             23824..25224
                     /gene="hslU"
                     /locus_tag="ACG804_000771"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HFS4831720.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            25242..26033
                     /gene="codY"
                     /locus_tag="ACG804_000772"
     CDS             25242..26033
                     /gene="codY"
                     /locus_tag="ACG804_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HFS4831721.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            26115..26990
                     /locus_tag="ACG804_000773"
     CDS             26115..26990
                     /locus_tag="ACG804_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HFS4831722.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(27122..27760)
                     /gene="plsY"
                     /locus_tag="ACG804_000774"
     CDS             complement(27122..27760)
                     /gene="plsY"
                     /locus_tag="ACG804_000774"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HFS4831723.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            27887..28321
                     /locus_tag="ACG804_000775"
     CDS             27887..28321
                     /locus_tag="ACG804_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HFS4831724.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            28487..30532
                     /gene="parE"
                     /locus_tag="ACG804_000776"
     CDS             28487..30532
                     /gene="parE"
                     /locus_tag="ACG804_000776"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HFS4831725.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            30544..32994
                     /gene="parC"
                     /locus_tag="ACG804_000777"
     CDS             30544..32994
                     /gene="parC"
                     /locus_tag="ACG804_000777"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HFS4831726.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            33271..35502
                     /gene="pflB"
                     /locus_tag="ACG804_000778"
     CDS             33271..35502
                     /gene="pflB"
                     /locus_tag="ACG804_000778"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HFS4831727.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            35746..36507
                     /gene="pflA"
                     /locus_tag="ACG804_000779"
     CDS             35746..36507
                     /gene="pflA"
                     /locus_tag="ACG804_000779"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HFS4831728.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            36592..37518
                     /locus_tag="ACG804_000780"
     CDS             36592..37518
                     /locus_tag="ACG804_000780"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HFS4831729.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            37700..38593
                     /locus_tag="ACG804_000781"
     CDS             37700..38593
                     /locus_tag="ACG804_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HFS4831730.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            38727..38852
                     /locus_tag="ACG804_000782"
     CDS             38727..38852
                     /locus_tag="ACG804_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HFS4831731.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(38986..39618)
                     /locus_tag="ACG804_000783"
     CDS             complement(38986..39618)
                     /locus_tag="ACG804_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831732.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
BASE COUNT        13862 a         6819 c         8323 g        10630 t
ORIGIN      
        1 aatctttcct catagcctat ctttgtcttt tttcttatag ttttttcagt aatcttgtct
       61 gtggcttcaa ataagtaaag ccttgccctt ccacttcatg cacattgatg attgaaagga
      121 aagctttttc gtcaatctcg tggacgatcc tcttagcttc agttaattca ctagagctaa
      181 cgaccatata gatgattttt tttgaattac cagagaatgc gccttctcca gaaaggaaag
      241 tcacacctct ttgcagaccg gtcatcagta gtggtgcaat ctcttcgctt ttgttggaga
      301 cgacaagtag accttttgca gaatatccgc catctaagat cgaatcaatc acacgactga
      361 aaacatacga aacaatcaac gtatacatca tacgtttcaa gtcgatatag gttaatgaag
      421 caagtaagac gatgatatca aatgccaata gggaacgccc catagtgatg ccgtaatttt
      481 gttctaaaat ccgagcgata atatcactgc cgcctgttgt tccacccatg cggtagacga
      541 tcccgcttcc tacacctgca actaaacccg caagtagaga aacgatcagt agatcatgct
      601 gtaaattgat ttctagtgga accctttgcc agatccataa aaagaatgac aaagaaagtg
      661 tacctagaac agtataggcc aaggaacgtt taccgaggat ctttcctcct agtaaaatca
      721 atgggatgtt gattaataaa gtcgtataag ctggatcaat accaaataaa gctcttaaga
      781 tcaaggtgat ccctgagact cccccttctg ctaaatgatt agcgatgttc aagtaaacaa
      841 gaccaaatgc ataaatactt gttcctataa tgataaaaag aacttctttt actgtttttc
      901 gtttgaccat atgaattcca gctttcaatt atgtattttc acagaatttc catttagaaa
      961 ttccttccta aatgtagcat ggaaattcga ttttctcaat tgctcttatc taggatttgc
     1021 gttaaagttt tggtaagata gttttggagg gaaaaagatg gataaaaagc gttctttata
     1081 cagtatgcag caggaagtgg atgaatatat ccagcaattc aaggtggggt atttctctcc
     1141 attagctcag atggctcgat taactgaaga agtaggtgaa ttggcaagag aagtcaacca
     1201 cacttatgga gaaaaaagca aaaaggcttc tgaaccagtt aactcggtag cagaagaact
     1261 tggtgatgtt ttattcgtta cgatgatcat ggctaattca ttgaatatcg acttaactga
     1321 agtttttgaa aaaaacatgg aaaaattcaa tcaaagagac cataatcgct ttgagcgtaa
     1381 ggacgagtaa acaagatgaa gtggtcctgg ccttgaagac tctgaaacgg acttgtcaaa
     1441 cagtcaccat gcaactgagt ctttatctca ggacaagaaa cacgcaggaa aggttggaaa
     1501 aatgaaatta aaacaattac ctctggaata ccaaaaggca attccagttc tgaaaaaatt
     1561 agagaatgca ggatatgaag cttattttgt aggtggaagt gttcgtgata tcttgctgaa
     1621 ccagccaatc catgatgtgg atatcgcaac aagcgcattt ccagaagaaa tcaaacagct
     1681 ttttccaaaa acgatagata ttgggatcga acatggaact gtgttggtat tagaaaatga
     1741 tgaacaatat gagatcacca catttcggac ggaatcaact tatcaggact accgtagacc
     1801 agatcatgtc gaattcgttc gttcgttggc agaagatttg aaaagaagag attttacgat
     1861 caatgcgttt gctttgaaag aagatggaga aatcatcgat ttgttcgatg gtctgcaaga
     1921 tctagaagaa cagatcttgc gagctgtagg caatcctcat gagcggttcc atgaagatgc
     1981 cttacgaatg atgcgcgggt tgcgttttgt cagtcaacta gggttcaaat tagaggaaga
     2041 aaccttctac gccatcaaag aaaaccacga gctattaggt aaaatatctg tagaacgtat
     2101 aaatgtggaa ttcatcaaga tgctcttggg aaatgaacgg gccgcgggaa tccatgcatt
     2161 tattgaaaca gagtgctaca tttgctgtcc cggtttgaaa gaagaaggcg aagcactttt
     2221 acgttttgct gaattaccat ccgtcccatt gaaagaagag agccaagcat gggcattatt
     2281 gatcagccaa ctggatctaa aagaaaatga gattcgttcc tttttgaaat cgtggaagtg
     2341 ttctaaccaa atgattaaag acgttcaagc acttgtccaa ggactacgac aacgagaaac
     2401 tggagctttg gaaccattcg aattgtactt cttaggcaaa aaacatgcac tgcaagtaga
     2461 agaattgatg atctattttg acgaaacacc tcagatggat gccgtaggag aatcctatga
     2521 tcgtttacct atcaagtcat taagcgaatt agcagtagat ggtaaaatct tgctagaaga
     2581 aactggaaaa aaacctggta agtgggttag tgaagctttg caattagctg aaaaagccgt
     2641 cgtagaacaa agaataaaaa atgataaaaa acaggttttg gattttttat cgaaagaaaa
     2701 attgatttaa aaaacactag actgtatctg ctcagctttg ttggctactt aaagtgggca
     2761 gatacgtcat tagaagaaaa aacataagat gtgaccactt acataaattt gtgctaaact
     2821 gaggtagtac aagaataaat tacatcataa aggagtcttt ttaatgagta aagaaatgac
     2881 agcgctaaaa ttttatttta gaaatggaga aacctggacg atcaaccgcc gtcatatcgg
     2941 cgatctttgg atcaaacaaa tcacaacaag ttttggacga atcaatggca gtgaatttgt
     3001 tgaaatccat ccgtgtgctg gatttaaaat cgaaatcttc catgaagggg acgcagttgc
     3061 gacacatgat atcaacctag gcggactgga aatgggcatg tttaatcgcg cattgaaata
     3121 cgaagatatc gagcgaatgg aaatccttta ccgaaatggc acacctgatc ttgtgtactt
     3181 cccatatcta gataaaggaa cagaaggatt agacaatcaa tatcaatcaa caaaaatcag
     3241 cgaaaaaaca ggtaacttgt atatcgtgat caatccagat caacgtgtag aagatgtata
     3301 cggggaattt ttcgaataaa tcgattttta cgcaaaaatg aggctgtgaa agagatgtgt
     3361 cttattacta ctgataggct gtctcttcca caccgtttat tcagaataag ggactgtgac
     3421 aagatttttg tcgcagcccc atttttttgt tgtgataaaa gaacaagaaa ggcaggaatg
     3481 ggaaagtaaa catccttttg tcagaaactt ttatctttct taagttttac ttgatatctg
     3541 atactatttg gaatagaatg aggcgttgaa aaatttatgg aaatttctaa ctagcaataa
     3601 acgatgaaac aatgaaatat ttttcatcca aaaagaactt tgctataatg atggaagttt
     3661 gtgtatagga gatctggaaa atgagagaga gttttgaaca acaaaaaaaa ctgttgcatg
     3721 atcgctatgg cgccctttcg atggatgacc gccgtcaaat actttgtaag ttgcgtaaaa
     3781 gaaatatatt gatgtatcgt cagttggaac gtctgaaaca tgatctgctt cgtttggagt
     3841 caaaacgtgt acagtgtgaa ttagagggga accaaacaca ggttgaagta gtcgaaacca
     3901 aaattttaaa gaaaaaagaa caatttttaa aaatgcttac acaaaataaa aaataaaggg
     3961 gatggacgat ggaatttgct gagttagtta ttgtatttgc agtaacgatc accttatcga
     4021 acatagctag ccgcattttg ccaatgattc cagctccact gatccaaatt ttccttggag
     4081 tggtattagg tctgacagag tggggacaat caatcgattt tgaacctgaa ttgttcttag
     4141 ttatgattat tgcaccattg ttatttagag aaggagaaaa agcagatatt tcttcgattc
     4201 tcaaaaattt cgggacaatt ttgttcttgg catttggagg agtcattttg acccttgtcg
     4261 gggtaggtgc gacgttatca ttcctgttgc caagtgtccc acttgctgcc tgctttgctt
     4321 ttggagcagc gttaggtccg acagatgcgg tagcagtcag ttctctttct ggacgagtga
     4381 atatccctaa aaaggcgatg catattttgg aaggagaagg tcttttgaat gatgcatctg
     4441 gtgttactgc cttccagttt gctcttggtg cgctgatcac cggatctttt tcagcagtaa
     4501 acgcggggat gagtctagta gtttctagta ttgggggagc tttgatcggc tttttgcttg
     4561 tctggttcaa acaaaaaata attcatttga tcgaaaaagc atcagcacaa gatgtcacag
     4621 ggtatctgct gatcgaactt ttgcttcctt ttctagccta tgtattggca gaggcatttg
     4681 atgtatctgg aatcattgct gcagtggcag caggtattct ccaagcttct ggttttagga
     4741 aaatctctgt gtttgatgca gaattgtcga gcttgtccca cagtacatgg acaactattg
     4801 cttttacact gaatgcatta gtatttatat ttttaggaat cgaattgacg caagtgttct
     4861 cgccagtatg gggagacggt ttatatccaa acggtctttt attagcgatt atcgtattaa
     4921 tctctgtcat gctttttgtg atcagattca tttctatcag tcttttttat gtattcaaag
     4981 atggcagtaa aaagttcaaa aaacagttga acgagatctt gatcttaaca tttggcggtg
     5041 taaagggaac agtcagtttg gctacgattt ttattttgcc attttcaatc aataatatga
     5101 tgttttacca gcggtctttg cttttgtttc tgacggcggg tgtcatctta gtgactttgg
     5161 tcatagggat cattgtcttg cctatgctga cggaaacaga ggaagcgaaa agcacggatt
     5221 tgaatgcttt gatgatttta gaagaggtcg ttgaagtttt gcgaaaagaa ataaaggaaa
     5281 ttgatcgtaa tacaaaagaa tttttagcca ctgaagcagt gatagaaaat tatcaagaac
     5341 ggatacgtga tctgtacttg gaagatttaa ccgatgatga aaagcaagaa gtacaagaaa
     5401 tacaagcact gattttgtcg atcgaacggg atggattgga tgaaagttat cgttcgggca
     5461 agctttcttc taatggttat cgtttttact cccgttttct ttctcgattc gaacattcta
     5521 tcacaagcca gattttgtct tttatcggct tttggttcat tgttgtccgt aggttaatgc
     5581 gaatcgttct ccatccgaaa atgttttggc aaagaagata tgctgatcgt cagacattta
     5641 ttagtgatga agatatccaa gaaatcagag agacatatca aaaaaatact cagttgatta
     5701 ttgaaagttt agataacttg actgatattt atgatgaaac gatggttcaa ttttttatcc
     5761 agcaacgcaa acttgaagga ataaaaatga actcggggaa tttgatttct tcgtggatga
     5821 tccagcaaga tagtctgttt acgaaaaaaa tgctaagagg ttattatctt gaaagaaaaa
     5881 tcattgatga atacgaagtt gctgaaaaaa tcacgacgtt ttctgcgaac agctatcgca
     5941 ggaatatcaa tttgttagaa tcttatacga tgaacaaacc atctgataac ttttctttcc
     6001 gatttgcgtt tcgagcaaag tcaaaaaaaa cgagtccaat aaaataaaaa ggtaaaaatt
     6061 ttcaagtttt ataaaaaaca aaacatatca gaacaggatc gaatcggtcc tgttcttttt
     6121 ttgagaacac aaaaagaaca aataccaaaa aaattttcct gaagttcact atttttatga
     6181 tacaatatcc aagataagga gggaacatgt tgaaagaatt aaaagtaact gacctcaaaa
     6241 aaacttatgg tgaaaaagat ttgtttgacc agatttcttt tttggtccac gaaaaagacc
     6301 gtatcgggtt gattgggacg aacgggacgg gtaaaacaag tctcttaaat attattgccg
     6361 gtatcgatag cagcgacggt gatcggcaaa cagtgtttta tccaactgat taccgtattg
     6421 gttatctttc tcaagcagct gaattttccg atgaattaac tgttctccaa gcagtctttc
     6481 aaggaaacag ccccttgatc caaactgttc gagcatatga ggaagcattg atcgaactag
     6541 gggaaaacgg agaagaccct gatgtgcaaa aacgttatgc taaagcagaa gaacaaatga
     6601 ataaagaaga tgcttggact acagatacca acgcaaagat tattttgcaa aaattaggaa
     6661 tcagtgaatt agataaaaaa atcagtactt tatcaggtgg tcagaaaaaa cgagttagtc
     6721 tggcgcaagt gttgattgat gaacccgatt tactattact agacgaacca acaaaccatt
     6781 tagattatga agcgatcgag tggttggaaa actatttgaa acaataccgt ggcgcactat
     6841 tgatggttac ccacgatcgt tattttctag atagagtagc aaaccgaatc ttcgaacttt
     6901 catttggaaa attatacgag tataaaggaa attatgaagc ttacgtctta gaaaaagcag
     6961 aacgtgatcg tgtagaagta gaacaagaag aaaagcgcaa gcggctttat aaacaggaat
     7021 tagcttggat gagggctggc gtacaggcac gtggcaccaa gcagcaagca cggatcaacc
     7081 gtttcgaaga tctaaaggag aacttgtacc aagtaaacca agaagatgat ttagagctga
     7141 acctagcgac acaacgttta gggaaaaaag tactggaaat caaagatggc agttaccgta
     7201 taaatgacca aacactgcta gaacatttag atttattgat tcaatctcgg gaaagactag
     7261 gtattactgg taaaaatggt gcgggaaaat cgacattgct taatattcta gctggcagaa
     7321 ttcccctgga tagcggtaca atgtctatcg gtgaaacggt tcatcttgcg tattatacac
     7381 aagaaaatga agaaatggca ccagataaac ggatgattgc ttacttacaa gaagctgctg
     7441 aagaagcaaa aacagcagat ggcagtcaaa tcggagtagc agaattactt gaacgatttt
     7501 tatttccaag atttatgcat gggacactga taggcaaact ttcaggcgga gaaaaacgcc
     7561 ggttattttt gttgaaactg ctgattcagc aacctaatgt tttattattg gatgaaccga
     7621 ccaatgattt ggacatagca acattgacga ttttggaaga ttattttaga agttttccag
     7681 gtgctgtgat cactgtttcc catgaccgtt atttcttgga caaggtagca gataagttat
     7741 tagtattcca aggaaacgga aaacaagaac tttattacgg aaacatgtcc agttatttac
     7801 tgaagcaaaa agagacccag cagcctgctg aaaaagcgaa accaaaaata cagagcaagg
     7861 aacctgctga aaagaagaaa ttatcttaca tggaacaaaa agaatgggaa acgattgaag
     7921 atgagattgc agaacttgaa gaaaaaatct cattgctcca agaagagatg aatcatcaag
     7981 gagataattt cactcgatta caagaattgc aaaacgacgt atctgaaaca gaagcacaac
     8041 ttgaagaaaa aatggcacgg tgggaatact tgagtgaatg ggtagaagat taggaggaaa
     8101 aaggatggaa caagcgtatc ttgacttagg aagaaaattg ttggaagaag ggcatcgtaa
     8161 agaagacaga acaggcacag gcacattaag cttattcgga taccaaatgc ggtttgatct
     8221 gcaaaaaggg tttcctttgt taacaacgaa acgagtacct tttggattga tcaaaagcga
     8281 attgctttgg tttttaaaag gagatacgaa tatccgctat ctattacaaa ataaaaacca
     8341 tatttgggat gaatgggcat ttgaacgcta catcaaaagt ccagactata atggaccaga
     8401 tatgactgat tttggccata gatgtttgac agatcctgaa ttcaatgaag aatataaaaa
     8461 gcagagcaag cttttttgcg agaagatcct aaccgatgat tcctttgctg aaacatacgg
     8521 cgatcttgga cacatctacg gctatcaatg gcgtcactgg gaaacaaaag acggtggctt
     8581 tatcgatcaa atcaaacaag tgatcgaagc aatcaaaaag actcctgatt ctagaagatt
     8641 gatcgtttct gcatggaatc cggaagatgt tcctagcatg gctttgcctc cttgtcatac
     8701 gatgtttcaa ttttatgttc aagagggacg gctaagctgc caattgtatc aacgcagtgg
     8761 ggatgtgttt ctaggcgttc cgttcaacat tgcaagttat gcgttgctga ctcacctaat
     8821 tgcacatgaa acaggtttag cggttggcga atttgttcac acattaggag atgctcatct
     8881 ttatatcaat catatcgaac aaatgaaaga acaattgagc cgagaaatac gcgcatttcc
     8941 gactttagtt ttgaatcagg aaaagcagtc agtatttgat tttgagatgg aagatatcca
     9001 attagaagga tatgacccac atccggcgat caaagctcct atcgctgttt agaatcagaa
     9061 aggatgagaa aatgttagct gcaatttggg cacaggatga aaacggattg attggaaaag
     9121 aagaccgtct tccttggcgt ttgccaaatg atctgaaatt cttcaaacaa atgacagaag
     9181 caaatacact agtgatggga cgaaaaacat tcgaagggat gggtagccgt ccgttgccga
     9241 atcgtcagac gattgttttg acgagagatt cttcctataa agcagaaggc gtgcatgtca
     9301 tgcatagtgt ggaagacgtg cttgctctgg aaaaagaaac agacggtatc tttttcatcg
     9361 ctggagggtc agctgtttat caagaatttc tgccattttg tacgatatta taccgtacag
     9421 tcatccatca tgtattcgat ggagatgctt attttccacc tgttgactgg tctgattggt
     9481 cactgatcaa tactagtcaa ggagaaatgg atgaaaaaaa tcgttatccg catcaatttg
     9541 aaacgtatca gcgtaatgag aatcctgtaa aaagcgggac aggcgaattg acgatataaa
     9601 aaagctatgg atagactagc tgttatttag agctgtccca tccatagctt tatttttttt
     9661 attaagtaaa gaataaaaca gagaagtaca taaaacctgc acctaacata acaaacaaat
     9721 gccaaacaac atgcatatag cggatagaat tcaagctata aaagaatgcg cctatcgtgt
     9781 aagaaagccc gcctgctacc atcaaaataa caccagtcat tccaagagag tgataaagag
     9841 gaacagcagc cacgacacag agccacccca taaaaatata gatgatcgta gatacttttg
     9901 atactctctc ccgtttatgc aacgtcaacg ctttatatat aatgccaaga atcgcaaaca
     9961 accagattaa tacaaataaa gtccaaccta gccatcctcg gatactcagc aaacaaaaag
    10021 gagtataact tcctgcaatc aaaagaaaaa tcgaactatg atcgaatact tggaacacct
    10081 tttttgcttt tgtaaaaatc aatgaatgaa acaaagtaga cgttaaaaat aaaagaatca
    10141 tcatcgatcc atagatagca taagagacaa tatggaggga ggaatgcaag tgggcacctt
    10201 ttactaaaag aaccactagt cccgcgatac tcaatccagt cccaattcca tgggtgactg
    10261 cattaaacac ttcatttaat atttcatacg ttcgattaaa tttcgttttt tccatgaaaa
    10321 cggctccttt actaggtgta attaatgaaa aatcattatt tgtctgttat actaaaaata
    10381 gaaattgtct tacatgtagt ttaacatgaa taaggcatct tgttaaagaa agagagagag
    10441 aaaataatga caaatgtaaa aatcgtaaca gattcttcat gtacgatgga aaaaaatgta
    10501 cgcgatgctt taggcattcg tgtcatgccg ctatccatca tgatcgacgg aacagtatat
    10561 cccgatgatg accaactaga cggcgaaaga tttatggaaa tgatggcgaa agcaaaaaat
    10621 ctgcccaaaa caagccaacc accaattgga gaattcatct cgatgtatga tgagctagga
    10681 gaagacggca gtgaagtgat ttcgatccat atgacaaaag gcttgagtgg aacagtagaa
    10741 gcagcaagac aagccagtaa tctaacaaaa acgaaagtaa cggttatcga cagtgatacc
    10801 actgaccaag gattatcttt tcaggtaatt cgagcagctg aattagcaaa agaaggtaaa
    10861 acagtagaga aaatccttga agaagtcaaa aaagtacaag acaatacaaa attatacatc
    10921 ggaatatcca cactagataa cttggtaaaa ggtggaagaa tcagccgaac aactggtttg
    10981 ctgtctagtg ttttgaacat acgcgtggtg atgaatttcg cccattctga attaatccct
    11041 gtaactaagg ggcgaggaaa gaaaacgttc gataaatggt ttaataattt gaaaaatgaa
    11101 ctgaaagaat tgccaaatgt gcgacaaatc ggtatttcac atgcggatgc aaaagaattg
    11161 gcgcaagaat tcaaagaggg tttgcaagaa ttattcccgg acatgcatat ccctgtactg
    11221 catacgaatc cggttatcgc tacgcatact ggtaaagacg cgtttgcaat catgtattat
    11281 gtagattagt cgaaaagagg ataagccctc agcctgaaag gcttgcagct tattctcttt
    11341 ttctttataa aattaggaaa ataattgttt tcttttttca taaagactac ctttttgata
    11401 aaatttttga taacattaga accaatcgaa tacaagaggt gaaaaaatga aattaacgaa
    11461 acgacatttg atcctcgttt tgttcccatt attaattgcg atcatcatct atgcaggttt
    11521 agctgcttct ataccgaaag ctggcccact aatgaaacca gtaactactg tgagagaaga
    11581 tccaaataaa aaagaaaaac ttcactacat agctatcgga gattcgctga ctgaaggagt
    11641 aggagatcaa accaagcaag gaggattcgt tccccttgtc gcaaatgatc taaaagaccg
    11701 ttataatttg accgcggttg aaacagaaaa ctatggtgta aatggtgaac gaagtgacca
    11761 gatcttaaag cgagtaaaaa caaaagaaga aattcgaaac aatatcaaaa cagctgattt
    11821 tatcacactg actgttggcg gtaatgattt gatgaaagtt atccaaaata atttattcgg
    11881 gttaacggtc aattccttta aaaagccact gaaaaactat caggaaaatg tcacagaact
    11941 attggaagaa tttcgatccc tcaataaaac cgcacctatt tacattttag gcatctacaa
    12001 tccattttat ttgaactttc ctgagatcac tgacatgcag acaattgtta acaattggaa
    12061 caaaggaaca gaaacggtga caaaaaaaat gccgaactgc tactttatcc caatcaatga
    12121 tttgctttat caaggattga atcaggaagt aggtgtcaca gaagaaggaa cagatcaaac
    12181 aactagcacg acagaaaatc taaatggcat caaaaataat gtgctctatg aagaagatca
    12241 tttccatcca aataatttag gttatcaatt gatggcaaat gcagtgagag atcagctgat
    12301 cgagacacaa aaccaatggt tagagaagga ggatgatcaa taaacatgaa aacaagatct
    12361 gacgtatctt caaacaaaac aaagaaaaca aattactgga aattcgcctt ccttatcctt
    12421 cttggggtag tacttggttc gaccgtattt ttaggcagcc gtatttttgc taatcgggaa
    12481 ccagaactcc cagaaatacc agctcttacg gaaagacaag gagatcctgt cttaacgatc
    12541 aattcaaata aagaaaaagt caatcaaatc atcagctttt tccttagtga gtatcaaaaa
    12601 gatagtgata ttgaatataa attttatttg gaaaatgaag cactactcaa tggtactttc
    12661 gaagtactag gttttcctat cgatttctat ttatattttg atccgtatgt gatggaaaac
    12721 ggaaatgtcc aactaaaagc tagaagtctt tctatcggaa cattgagttt gccaatcaaa
    12781 gatgtgatga atatgatcaa gagaaactat aaattaccag attggatcga agtcaataca
    12841 gatgatctga ctatcatgct taggttggat caattccgaa tgcaaaacgg gatgtatatt
    12901 aaagcagata aaatcgactt agtaaatgat gacattcggt ttagtctata tttgccaaaa
    12961 gatacctctg atgcttcaaa caactcaaat accaacaaaa ctagcaccag cagtactgaa
    13021 agcaagacaa aagaaaataa aaaatcatcg gatgagtagt attagagggg gaatcataat
    13081 ggaacgagca atatttgcag gaggctgctt ctggtgtatg atccagcctt tcgacacgct
    13141 tcctggtatc catacagtga tgtcaggata tactggaggg catgtaccag atccgactta
    13201 tgaacaagta aaaagccaaa cgactggaca tacagaagca gtggagatta tctatgatcc
    13261 aacattgatt tcatatgaac aattagtaga actttactgg cagcaaactg atccaactga
    13321 cgctttcgga caattcgagg atcgcggtga caattatcgc ccggtgatct tttatttgac
    13381 agaagaacag cggatcattg ctgaaaaaag taagaaacag ttagctgaaa gtggacgttt
    13441 cgaacagcca atcgttacaa aaatcgaacc agcccaacca ttttatctag cagaagaaga
    13501 ccatcaagag tattataaaa agcatcctga aaattttaaa agaaaccatg cacgccgggc
    13561 tgcctttatc gaagaaaatt ggaggaacga agggtgaatc gaagcttttt tcattattta
    13621 atgacactgc gaggcggtgg cacacatgat gctttatctg ttttcgctac agaagccggt
    13681 aaagacatcc aatttcctaa gcacagctct agctacgaag aaatttctaa ttatctggaa
    13741 ctgaatgtcg actatttgcc gtccatggat atctttgacg aagcatggga aaaatattta
    13801 gaaaataatc atgacatata agagatagtt ttgtacttta tgatcaaaaa agttttttgt
    13861 ccaatagcct aattgaaaga attattttta tttcagctat ctagtcgcat ttttttgata
    13921 tttttcttat aataaagaaa gaatgaaaaa aagagggatg gattgataga gattgacaaa
    13981 aaaacaacgc tatattaatc gcttctggct tgtattcaaa tacttacttg tttctgtatt
    14041 ccttgcgttc atgttgcggg gatttttatt catcccggta ccagtggaag gcaattcaat
    14101 ggaaaacgtg ttgaagcaag gtgatatggt tgtgatggaa aaattttcgg agatcagacg
    14161 atttgatatt gttgtttttc aattagcaga tggcacgatt tatatcaaac gagtaatcgg
    14221 tcttccagga gaaaatgtca gctaccaaaa tgatcaattg aagatcaatg ggaaagtagt
    14281 taaggaacct tatctaacta aaaacctgaa atcagatcat gcaaatgcat cctatacgac
    14341 ggactttaca ctacaagagc taacgggaca atccaagctt ccggaagata attattttgt
    14401 acttggagat aatcgaagag tttcaaaaga tagtcgttcg tttggcacga tcaataaaac
    14461 tgatattcta ggtaaagcaa gatttgtcta ttatccactt gatgaaataa aatggatcca
    14521 gtgagaaaca ataaagcgtg cagtctgttg agactgcacg ctttattgtt taatccaaaa
    14581 tcagtttact accttagtac gtaaaatcaa acagctcgtt taaacacttt tctagcctct
    14641 aaagttttga taaatgaata aacaaccatt atttgaatag ggatttggat catattcctg
    14701 atgaatctac ctagaaaaat tactttgaaa tctgcaccaa acaaaacaga catcagccaa
    14761 gaattgataa aaaggctgac tgggatcata atcaataatt gggcagcgat gacggaaggc
    14821 aggtttatct ttttatgata taaaaataag ccattaataa atccaccaag gaaagccgtg
    14881 ataagaaaag cagcttgaaa cgttcctgaa ccaaatatcg tgaaatttaa agtgttcgac
    14941 aacatttcaa gcaaaccagc ccagatcggt ccatatagat aacccataag cgccatactt
    15001 aaaaatccga atgtgatttg aaaataagca ggaccaatcg ctatcttgta taagatgaca
    15061 tcaagggcta ataaaagagc agaggtcgac aacaatcttg cattcatttc gggcaatcta
    15121 aaaacgtctt ttgcaatcaa agtgttcaaa atattctctc ctttgtcagt taataataaa
    15181 aggataccat aaaatcacca atgtgtcatg acacattggt gatttacata cactggcatc
    15241 taacaattaa aaaaagggtg agaagactgc ttttataaac tgtaaaaaag agattgtacg
    15301 aataaaaaaa atagaggcgg agaatactta tcgtatcatc cgcctttgtt tttttgttat
    15361 aaaaaacgtc agattagtta tctgcttaca tcttcatcca tacgggttct aatgtatttc
    15421 cgtctagatc ttggacttct aatgaaaaca tttcttcttc aggcattccc atatctactt
    15481 cgtggaaagt accaccattt tcttttgcaa tttgagcaaa tttttttact tcatccgcat
    15541 tttcaacact aaacgaaatc aaagcaccac ttgttttttt attatcagct atttctttat
    15601 cttttataaa ttttttataa aaatcatgag agagaagcat tatccaaaaa gtgtcatccc
    15661 ataccattga accagcttct tcagtagaaa attcttcatt ttttttaaaa cccagctttt
    15721 cataaaaagc aacggaacga ttgacatcag caacaggaaa attaacaaaa accatactat
    15781 tcatttgttt cgtctccttt ctgttttgtt cgtctatcat ctcttattta ggaaacgctg
    15841 tcaaaaattt agattcatat atagaaacca aaataaaaat ttgcatcatc aaaaaagtga
    15901 agatgtgata gaatgaggac tggttcactt tcacttaact aatagatgga atttctttat
    15961 aataaaaaag tgaatttata ttgaaaaaga aaaaaacaag taaagccggg gaatattccg
    16021 gtatgaaagg aatggagaga acaatgacca tccaatggtt tccgggacat atggcaaaag
    16081 cccgacgaga agtttctgaa aaaatgaaat atgtggacat cgtatttgaa ttggtagacg
    16141 cacgattacc tttatcttct cgtaatccaa tgctagatca gatcattcag caaaaacctc
    16201 gccttgtttt attgaataaa gcggatctgg cagatccaca acagacaaag ctgtggcaag
    16261 aatattttcg taaacaaggc catcttgcat tagctatcac ggcacaagaa agtaaaggaa
    16321 ttaaaggtct agtacctgcg gctaaagaag cattgaaaga aaaacgggca agagatgctg
    16381 ctcgggggat caagcctcgc gctattcggg caatggtctt aggtattcca aatgttggga
    16441 aatctacgtt gatgaatcga ctagtaggca agaaaattgc acagacagga aataagcctg
    16501 gcgtaacaaa aggtcagcag tggcttcgtt taggtaatga gttggaattg ttagacacac
    16561 cagggatttt atggcccaaa tttgaagatg aagaaatcgg caaaaaacta gcgctgacag
    16621 gcgcgatcaa agaccagctt gtccatttag atgatttagc gatttacgga ttagactttt
    16681 ttgcccgata ttattcagga agaatcagcg atcgttatgg tttatcaatc gagcaagaag
    16741 aaaaattggc accggaatta ctgatggata ttacagcaaa acgtgggtat aaagaagact
    16801 atgatcgtgg cagcgaatta gtcgtgcatg atattcgtca aggaaaactt ggacgataca
    16861 cactggatcg ttgcgaagaa atggagcaaa aaagtgatga ctgaatccat ccaaagtatc
    16921 aaagaacgat tgaaaagcat acagagaata gatgatccta cactagaatc attaagaaat
    16981 gatccacgca aaggcgtgca gcaagcactg gcttcttttg aacgacgatt gaaaaaggaa
    17041 gcattaatta aggaaaaata tgaagaaatg ttttgctttg aaaagcaagg gtacgcacaa
    17101 ggtcaccaat ggattgccgg cattgatgaa gtaggaagag gaccattagc tggacctgtc
    17161 gtggcagctg cagttatctt gccgaaaaat gagatcatat tagggctgaa tgactccaaa
    17221 caattatcag agaaaaagcg agaacttctt tatcaacaag ttcaagaaaa agccctggca
    17281 atcgggatcg ggatcgttga tcagcagaca atcgatgatg tgaatattta tgaagcaagt
    17341 aaattagcga tgatccaagc agtagaaaaa ttgtccattg taccaagcta tttgttgatc
    17401 gatgcgatga ccttggattt gcctattcag caggaaaaaa taatcaaagg ggatgcacga
    17461 tctgtgtcga ttgctgctgc aagtatcatt gctaaagtat atcgagacca attgatgaaa
    17521 gaatatgacg tgctttatcc tggatatggt ttctcgcata atgcaggtta tggaacaaag
    17581 gaacacttag aaggacttga acgacaagga attacgccaa tccatcgtaa aagttttgca
    17641 cctgtaaaaa aatatttaca ataaaaaaca gccgctttta cgtatcttat tagaaagaga
    17701 gacgaaaggc ggttttatga tgtatcaaat agaagaaaat ttattgaaac ttgcttatac
    17761 aaaaggaatc agtagtcaag gaaaatgggc acttgctaac tggatgatgc agtatcctta
    17821 taaagaaatc ggatttgaag acatcattaa gataggtaaa ataaccaaac accgggagct
    17881 gtttcgcaaa agttggcagg aaattcacgc taactggggc aaaatccaat cgaaacagtc
    17941 gtttatcact tgctttgatc ccaaatatcc ccctcagctg cttcacttga cctatccgcc
    18001 aattgtactg ttttataatg gtgatctatc tttactttct tgtaacatgt taagcgttgt
    18061 tggtggaaga cacacttctg ctttagccaa aaaaacagtt tattatttac taaaaccagt
    18121 gatagaagct ggatatgtga tcgtcagtgg ctgcgcgaaa gggatagata catacggtca
    18181 ccaagcagca atctctcatg gtggacggac aatcgcagtc attggaacag ggatagagca
    18241 agtctatcct gctgaaaatc gtgacttgca agaggtgatt gcaaatgatc atcttctttt
    18301 gagtgaatat cctcctcaat ccggcccgaa aaagcattgt tttccaatga gaaatcggat
    18361 tatcgcagct ttgtctaaag gaacatgtgt ctttgaagcc aagaaaaaaa gcggctctct
    18421 gataacagca cagcaagcat tggatcttgg aagaacagtt ttttctgttc caggaaatat
    18481 tttaacagaa cattctaccg gatgtcatca tttgatccaa gacggtgcag tttgcacggt
    18541 ttcgggtgaa gatatcttgg cagaatttaa agaataacac catacttttc atttgctttt
    18601 cttgacaaac gttttctgaa tggatatgat tagctacgat ttgtatgaat cctcttttaa
    18661 tagtaggaac acgacaatgg aaaggagtcc attcagtaat ggcgtataaa tatttagtga
    18721 ttgtagaatc acctgcaaaa gccaagacaa ttgagaaata tcttggacga aactataaag
    18781 taatggccag tgttggccat ataagagatt taccgaaaag taaaatgggt atcgattttg
    18841 aaaacaatta tgaaccccat tatatttcta tacgcggaaa aggcgatgtc atcaaaagcc
    18901 tgaaagccgc agcaaaaaaa gctcaaaaag tttacttggc aagtgacccg gatagagaag
    18961 gagaagcgat tgcttggcat ttagcgtacc tacttgggtt ggatctgaaa gaaaaaaatc
    19021 gggtggtctt caatgaaatc acaaaagacg cagtcaaagc agcttttaag gaaccaagaa
    19081 cgatcgatgt agatttagta gatgcacagc aagctcgtcg taccttagac agaatcgttg
    19141 gttattcgat cagtcctatt ctctggcgta aggtcaagaa agggttaagt gcaggacgtg
    19201 tccaatctgt cgctttaaaa attattattg accgtgaaaa agagatccga gaatttgttc
    19261 cagaagaata ttggagcatc gacggtaatt ttaaaaaagc tcgcaagaaa ttcaaagcaa
    19321 atttctgggg aatcgacggt aagaaaaaga aattaccaga tgcacaaagt gtaaaagaag
    19381 tcactgctag aattgatgga acagacttcg aagttaaaaa agtagaaaag aaagagcgca
    19441 aaagaaaccc tgcgaatcct ttcactacaa gtagcctgca acaagaagct gcccgtaagt
    19501 taaactttcg aacaagaaaa accatgatgg tagcacagca attatatgaa ggaatcactt
    19561 tgggtaaaca aggaacagtc ggcttgatta catacatgcg tactgattct acccggattg
    19621 ccgatacagc aaaagcagag gccgcagcat ttattgaaga tacgtatgga aaagaatttt
    19681 ctagacatga tcaccgaaag atcaaaaatg ctcaaggcgc acaagatgcc catgaagctg
    19741 tgcgtccaac gagtgtgctt cgtacaccag atgaactcaa acaatattta gataaagatc
    19801 aattgaaact ttatacattg atctggtcac gttttgtggc tagtcagatg acaccagcta
    19861 ttttagatac aatgaaagtg acattagaac aaaatggtgt catcttcatt gcgaacggtt
    19921 caaaaatcaa attcaaagga ttcatgcaag tgtatgtgga aggtagagat gacggcaaag
    19981 aagagaaaga aaatattctt ccagaacttg aagaaggcga tgtagtccaa tctgttgata
    20041 ttgaaccaaa acaacatttt actcaaccac cagcacgttt tagtgaggct acgttgattc
    20101 gtgcactaga agaaaacggg gtagggcgac cttccactta tgcaccaaca cttgatacga
    20161 tccaaagacg ctactatgta aaattgacac aaaaaagatt tgagccgact gaactaggag
    20221 aaattgtcaa ttcattaatc tgtgaattct tccctcaaat cgtcgatatc catttcacag
    20281 cagaaatgga aggagatttg gataaaattg aagaaggcac ggaagcgtgg gtcaaagtgg
    20341 ttgatcgttt ctataaaccg tttgaaaaag aactgacgaa tgcggaagaa aaaatcgaaa
    20401 aaattcaaat caaagatgaa ccagcaggat tcgattgtga tgtctgtgga catccgatgg
    20461 tgataaaatt agggaaatat gggaagtttt atgcttgcag taattttcct gattgtcgga
    20521 atacgaaacc aatcgtaaaa gaaatcggtg tgacttgccc agtatgtcat gaaggacaag
    20581 tcattgaacg aaaatctaag aaaaacagac tattctatgg ttgttcccgt ttcccagaat
    20641 gtgaattcac ttcttgggat aaaccagtgg gcagaaattg tccaaaatgt gacggatatc
    20701 tggtcgagaa gaaagtcaaa ggcggtaaac aagtagtctg tgtaaatgga gattacgaag
    20761 aagacatcca aaaataatag aaaagaggtt ctttcattga aaatggtaaa tgttgttgga
    20821 gcagggcttg ccggaagtga agctgcttgg cagatcgcac aagcaggagt ccctgtccgt
    20881 ttatatgaaa tgcgtccagt caaatcgact gaggcgcatc acacaagtaa ttttgctgaa
    20941 ctagtatgtt ccaattcatt aagaggaaac agtttggcta atgcagtagg gttattgaaa
    21001 gaagaaatgc gccgattgaa ttcggtagta atcacttcgg cagatgaaac agcagtgcca
    21061 gctggtggtg ccttagctgt tgaccgcgat tctttttctg aaacaattac ccgaaaagtc
    21121 aaagagcatc cattagtaac agtgataaac gaagaaatta ctgaaatacc ggaaggaatc
    21181 accgtagtag caacaggacc tttgacttct catccattag cagaaagcat caaagcattc
    21241 aatggttcag atggttttta tttctatgat gcagctgcac caatcgtaga caaagctacg
    21301 atcgatatgg ataaagtata tttgaagtcc cgctatgaca aaggagaagc agcttacttg
    21361 aactgtccga tgacagaaga ggaattcaaa gctttccatg aggcactaat caatgccgaa
    21421 gtggcagaac ttaaatcttt tgagaaagaa aaatattttg aaggatgtat gccaattgaa
    21481 gtaatggcac agcgaggatt caaaacgatg cttttcggac ctatgaaacc agttggattg
    21541 gaagatccta aaactggcaa acgtccttat gctgttatcc agctgcgtca agacaatgct
    21601 gcagcttctt tatacaacat cgtgggcttt cagactcact tgaaatgggg cgagcaaaaa
    21661 cgtgttttcc ggatgattcc tgggttagaa aatgctgaat tcgttcgcta tggtgtgatg
    21721 caccgaaaca gctttatgaa ttcgccagaa ttgctgaaac cgacttacca atcaacgaaa
    21781 cgcgaagatc tgttctttgc aggtcagatg actggtgtag aaggctatgt tgaaagtgca
    21841 gcgagcggac tacttgctgg aatcaacgcc gcacgcttag caaaagaaat ggaaccagtc
    21901 gagtttccac aagaaacagc tattggaagt atggcttact acattactca tgcggaagga
    21961 aaacatttcc aaccgatgaa tgccaactat ggtctgtttc ctgaactgcc agagcgcatt
    22021 cgagacaaaa aagcaagata tgaagcaatt gcacaacgag ctttaaaagc taatgaggca
    22081 ataaaaacag aattagaaaa aactgcaatc ccaaatgagt aaggaaactc catgaagagg
    22141 gtgagacgga tagtctcgct ctttttcttg cgtttttctt aagaatttct caaacaaaat
    22201 gtgaggaatt gcgccaattg tgaacaaact tagaaatatt ggttaaattc tgacaattta
    22261 tttgtctttt tataaacgct gtgctaaatt attctctggg acaaaaggaa ggtgagaaaa
    22321 tgacagaagc cacgtgggaa caaaaatttt tgcgttattt gattgtcgaa agaggatatt
    22381 cagaaaaaac gaaagaagca tatgaagaag acattctcca tttcaaacat tttttggagg
    22441 aatctggaga cgctgatctg ctgaaggcgg aatattttac ggttcgtgtc tatttgagtg
    22501 cattagctga tcatcgtcct agctatagca gaaattctat cagtcgcaag atagccagcc
    22561 tacgttcgtt ttatcagtat cttctcaaag aagaagtgat aaaagaaaat ccattttctt
    22621 acgttcatct caaaaagaaa aatttgagac tgccacgttt tttttatgaa aatgaaatgc
    22681 aagcactttt tgacagcgta gcaggagata gtcctttgga tttgaggaac cgcgctttac
    22741 tggaagtcct ttacgggtca ggcatccgtt taagtgagtg tagcagtttg tcggtatcag
    22801 acattgattt tgattcagag gtcatgttga tccatggtaa agggaacaaa gagagatatg
    22861 ctcctctagg ttcttttgct caagatgctc tgcaagaata tttcagggaa ggccgccagg
    22921 tattgatgac aaaatatcac gaagagcatg atatcgtttt tgtgaatcat catggaaaac
    22981 caatcacgcc tactggaatt gaatatgtct tgaatcaaat gatcaaaaaa agcagtttgg
    23041 atagtgatat ccatcctcac atgctgcgcc atacatttgc tactcattta ttaaataatg
    23101 gggcagattt gcggacagtc caagaattgc taggacatgc caatttatcg actacccaga
    23161 tctatgccca tgtaacaaaa gaaagtttac aaaaaaacta tcgttctttc catccaagag
    23221 cgtaaaaata aggaaaagaa caaatttagg aggaaacaaa catggtcgaa tcaccatttc
    23281 attcaaccac tatctgtgcc gtcgaaaaag acgggaaatt tgctatggct ggagatggcc
    23341 aagtaacaat gggtgaatct gttgtcatga aaggcactgc aaagaaagta cgacgtatct
    23401 acaatggaga agttgttgta ggtttcgccg gaagtgttgc agatgcgttt actttagaag
    23461 aaaaatttga aggcaaacta aacgaatata acgggaatct acaacgcgca gctgtcgaat
    23521 tagctcaaga atggcggaca cagcaatcta tgcaaaaact tgaagcgatg ctgatcgtaa
    23581 tgaatgataa agaaatgctt cttgtttcag gtacaggaga agttatcaca ccagatgatg
    23641 gtatcttagc tatcggatca ggagggaatt ttgcgttggc tgcagcccga gcaatgaaaa
    23701 actatgctca aaacgacatg agtgcgaaag aaattgcaga aaatgcgtta aatattgccg
    23761 cagatatctg tatctttact aatcataata ttatcgtaga agaactgtaa gaggtgagta
    23821 gatatgtatg aattaaaaca aacaccaaga caaatcgtaa gtgaattaga tgaatatatc
    23881 gtaggacagc acgcagcaaa aaaatctgtt gccgttgctt tgcgtaaccg ctatcgccgt
    23941 ttgcagttag atgaaaaaat gcaacaagat attacaccaa aaaatatgct gatgatcgga
    24001 cctacagggg tcggtaaaac agaaatcgca cgacgtttgg caaaaatcgt caatgcacca
    24061 tttgtcaaag tcgaagcaac aaaatttact gaagtcggtt atgtcggaag agatgtagaa
    24121 tcaatggttc gggatttagt agaaaatgcg atccaaatcg tagaaaaaga gcagtacagc
    24181 cgtgtataca caagtgctaa aaaaaatgca gaaaaacgtt tggtaaaaat cttggtacct
    24241 ggtatcaaaa aagaacagaa acaatccact aatcaatttg aacaaatgat gaatcttttt
    24301 aatgctagtc agcaaaatac cgctgaaccg caagaagaag tgacagaaga tattcgaatc
    24361 aatcgccgta cagtcttgga acaactacaa aagggtttac tggatagtcg tgaagtaacc
    24421 attgaagttg aagaccaaaa gaaacctgca ccaatgatga acaatggatt ggagcaaatg
    24481 gggatcgacc taaatgaaac tctaggtgct ttgacaccga agaaaaaagt ggaacggacg
    24541 gtaacagtca aagaagcttt agagttattg atcaaggaag aatcagcaaa attagtcaag
    24601 gatgctgata tccatagtga ggcaatcaaa ttagcggaag aaagtggaat tatttttatc
    24661 gatgaaatcg ataagatcac ttctaaatca cagcaatctg gagaagtatc cagagaaggc
    24721 gtccaaagag acatattgcc aattgtcgaa ggttcacaag taaacacaaa atacgggatc
    24781 atccaaacag atcacgtcct attcattgct tcaggagctt tccatttgtc taaaccaagt
    24841 gatctaattc cagaacttca aggacgcttc ccgatacggg tagaattaga tgatttgaca
    24901 gctgaagatt ttgtgaagat tctgaccgaa ccaaataatg ctttagtaaa acaatacgtc
    24961 gcgttgatcg gtacagaaaa tgtgtcagtt acgtttacaa aagaagcaat tgaacggatc
    25021 gctcaaatcg ctttcgatgt caaccgtgac acagataata tcggcgcacg cagactgcat
    25081 accattttgg aaaaactact agaagatcta ttatttgaag caccagatat gcaaatggga
    25141 gaaataacga tcacagaagc atatgtggat gacaaacttg gctcaattgc ggcaaatgaa
    25201 gatttaagtc gctatatttt ataaaaaatc ggaggacgac aatgacagac ttgctaacga
    25261 aaacccgcaa gataaacaca cttttgcagc aaaagaatac ttttgacatg caagcagatt
    25321 tgccttacga taaaatggct gtcacactag gtggtattct tgacagcaac acctatatca
    25381 taggaagtga cggagtatta ctaggttata atgaacgtca cgatgtgaac aatgaacgaa
    25441 tcaaaacaat gtttgttgag aaacaatttc ctgaatctta tactgataca gtggcacagt
    25501 tgatgaaaac tgaagctaat atcccaatta ctagtgatat tactgcattt ccggtagagt
    25561 caagagagaa atatccattt ggtctgacga ctgtcgttcc gatctttgga gctggcgaac
    25621 gtttgggtac gattatctta tctcgtatgg aacaatcgtt tgcagatgac gatctagtct
    25681 tagcagaata tggagctacg gttgtcggta tgcagatcct ttatcagaag tctcgaagca
    25741 tcgaagcaga tgtacggagt gcaacggctg tccaaatggc aatcaacaca ttatcttata
    25801 gcgaattgaa ggctgtacaa gctatctttg aagcattgga tggagatgaa ggtcgtctga
    25861 ctgcttctaa tattgccgat agtatcggca tcactcgttc tgtgatcgtc aatgctttac
    25921 gaaaattgga atcagctgga atcattgaat ctcgttcgtt aggcatgaag ggaacttatt
    25981 taaaagtatt gaattcccgt tttaaagacg agttagcaaa acacagttat tagaagtaag
    26041 gggactgggg cagatagaaa tgtttgttcc agccttccca ttttaaaaag taagtcgaag
    26101 ttggaggaat ggcaatgact gttattattc aaaatgacca gctgatcgcc gaaatcgctg
    26161 aacacggtgc ggaattgatc agtctgaaat caaaagaaca tggtttagag tatatctggc
    26221 aaggtgatcc agcgtattgg ggcagacatg caccggtttt attccctttt gttggacgtt
    26281 taaaagatga tcagtatgtt tatcaaggga aaacatatca aatggggcaa cacggatttg
    26341 ctcgggatat ggattttgaa gtcattgaac atggacaaga aatggctagt ttcatcttaa
    26401 ggagtacgcc ggagacatta gaaaagtatc catttgattt tgaattagtg atcagctatg
    26461 aattaggagg agacggcatc acggttcatt atcaagtggc aaataccggt gaaaaagaaa
    26521 tgttcttttc tatcggtgga catcctgctt tcaatgtacc tcttgaagaa ggattgtcat
    26581 ttgaagattt ctatctggca ttttctccat tgaaatcaag attacgccta ccattgaaag
    26641 gcccattcat cgatatggat caaaagacgt taggtcagac aaatacgaat ctggctttga
    26701 atcgtgaact ttttgagcaa gatgccttgg tttttgaaac aaggggtcta aatgcgtacg
    26761 ccattcgaag tgaaaaatct tcccatagcg taactttaag ctataaagat atgccttatg
    26821 tagggatctg gtctccttat ccaaaagaag cgcctttcgt ttgtatcgaa ccgtggtgcg
    26881 gaatcgctga cacggtgaac agtagtggaa acttgatgga aaaagtaggg atcaatcaac
    26941 taggtgccca tgaaatcttc aagacaaaat attccatcac agtgaagtaa gaggttgtga
    27001 ccgagaagtt agcagggaac accgtttacc aaggtgtgta aaaaagctat cctgtaagta
    27061 ataagggagt gtgacatcga tttgtcacac tcccgtttta tctctttgga atgaaaaagt
    27121 atcaggattt tttcttgctg ctattcaaac caaacgggat tcgactttca gtatggtttc
    27181 tgatacgctt gatattgtct ttatgccgat aaaagataaa ggaagaaact aaaaaggcaa
    27241 tgatcgtcag taaccaattg ggcttagcca aaatcacagg agctacataa ggaaggacga
    27301 tcgtagataa agtgatcaat actgcactga tcatactgct caaactcacc atacttgtac
    27361 aaaataaact aacgataaag atgatacaag aataaacaaa aaatacagga ttaaatccta
    27421 aaagcattcc tgcacttgtc gcaacagctt ttcctccttt gaacccagca aaaatcggaa
    27481 atgtatggcc aagaatggcg cataccccaa accaaagagg gttaatccca gaaaggtgga
    27541 agatcatcgg caaacaagta gccaatgtac cttttaaaat atccataagc aggacaacaa
    27601 tcccggctgt tttgcctaat acacgaaatg tattggtcgt tccagtatta ccgctcccgt
    27661 gttgtcggat atcttttttg aaaaacaatt tgccaatcca gacaccggaa ggaatagaac
    27721 ctaaaagata tgctaaaata agtaataaga tcaatttcat tttttaccct ctttcaagtt
    27781 gaaaactatc ctttatttta gcatgaatag gtaacaggaa caattgaaaa aatgaaagat
    27841 acaagtataa tagatggaat aaaaagaaaa gcaaggggtg gcagaaatgt ctgtaaaaaa
    27901 tccaacacaa gaaacgattt tcaactattt ggaagaagca aaaaatattg ccgtcgtagg
    27961 cttgagcaat aaaccagaac gaacaagtta catggttgca caggtattgc aagacaatgg
    28021 atataaaatc ataccagtaa atccattatt ggctggtgaa gaaattctag gcgagaaagt
    28081 ctatgcgaat ttgacagaaa tcgatgatcc aatcgatatc gtagatgtat ttagacggag
    28141 tgaattttta cctgaaatag caggtgattt tttgaaaact gatgctaaag tgttctgggc
    28201 acaattaggg attgaaaaca aagaagcagc tgagatgcta agaaaagcag gacgtacaga
    28261 tatcgtaatg gatcgttgta ttaagattga acttggtaag ttgaaagaaa accaaaaata
    28321 aaaatgacca caaagaagag atgatcgata gaggggaatg tcgaaaaagc ggttaggaga
    28381 taattaaaat tgatttctcg tctaccctct tttttttcac gaccttttct agtatgataa
    28441 tcgtggtgcg gttttgccgc aaagtattat tgaaggagcg tttgccttgg caaaaaaagt
    28501 aaacaacgaa tacaatgact cgtccatcca agtattggaa ggattagagg cagttagaaa
    28561 aagaccaggg atgtacattg gatccactga cagccgaggc ttgcatcatt tagtctatga
    28621 aatcgtcgat aatgcagttg acgaagcatt atcaggttat ggcagtgaga ttgatgtgac
    28681 catccatgaa gacaatagta taactgttgc agatagcgga cgtgggatgc ctgtaggaat
    28741 gcatgcttcc ggaataccaa cagttgaagt gatttttact gtgctgcatg ctggcggaaa
    28801 gtttggtcaa ggagggtaca aaacttctgg tggactgcac ggtgtaggag ccagtgtggt
    28861 aaatgcctta tcgaaatggc taattgtaac gatcgttaga gatggcgtag agtatcagca
    28921 gaaatttaaa aacggcggta aacctgacgg tactttgaaa aagataggaa aaacaaaaaa
    28981 agcaaacggg acgactgtcc attttttacc agatgataca atattcagta caacgaaatt
    29041 ttcatatgaa attttagccg aacggttaag agaatctgcc tttcttctaa aaggcgttaa
    29101 aatctctctt tctgatcttc gtggagaaga accagtcaag gaaatttttc attacgaaga
    29161 aggaatcaaa gaatttgttg attatctgaa tgaagaaaaa gatacattga caccagttgt
    29221 ttatttttca ggagaaaaag aaggtatcga agtagaggtc gcttatcaat acaatgacgg
    29281 ttattcagaa aatgttttat cttttgtcaa taacgttcgg acaaaagatg ggggaaccca
    29341 tgaagctggt atgaaagcgg cgatgacgaa atcttataat gaatatgcga gaaaagttgg
    29401 tttgctgaaa gaacgggaca agaatctgga aggtagtgat ttcagagaag ggttagctgc
    29461 tgtactttct atccgtgtac ctgaaaatct tctgcaattt gaagggcaaa caaaagaaaa
    29521 acttggtacg ccagttgctc gtaccgtagt agataacgtc atcagtgaac aaatgggctt
    29581 ttatttgcag gaaaatagcg aaatgagcca gatgttggtc cgtaaagcaa tcaaagccag
    29641 agaagcgaga gaagcagcac gtaaagccag agaagaaagc cgaaatggga agaagcgtaa
    29701 aaaaggcgaa tctcttcttt caggaaaatt gacacccgca caatcccgaa accctaagaa
    29761 aaatgaattg tatttagtcg aaggggattc tgctggcgga tctgctaaac aaggaagaga
    29821 cagaaagttc caagcaattc tacctttacg aggaaaagtc atcaataccg aaaaagctaa
    29881 aatgcaagat atcttgaaaa atgaagaaat caatacgatg atctatacga ttggtgcagg
    29941 agtcggtcct gagttttcta tcgaagactg taattacgac aaagtaatca tcatgaccga
    30001 tgcggataca gacggcgccc atattcaagt attactgctt actttctttt atcgttatat
    30061 gaaaccgctg attgaagctg ggaaagtata tatcgcgtta ccgcctttat ataaagtatc
    30121 caaaggacaa ggaaagaagc aagtcattga atatgcgtgg acagatgacg aattggcagc
    30181 aatgattaaa aaagtcggca aaggatatat gctgcagcga tataaaggac ttggagagat
    30241 gaatgcggaa caattgtggg aaacaacgat ggatccgact tcccgtacgt tgatccgcgt
    30301 ccgtatcgat gatgctgcgc aagctgaacg tcgagtaacc acactgatgg gtgacaaagt
    30361 agaacctcga agaaaatgga tcgaaaatca cgtgcaattt acgctcgaag aagatggcag
    30421 tatcttagat aaaaaagagg atactgaaat ctctccttca gtttctaatg atttattaga
    30481 tgaagaacga gcagataaaa atgaaaacaa tcagttattt gaagtagaat aggaggtcac
    30541 ctgatggaaa atcgacaaga agtacaagaa ttaactttag aagaagtgat gggtgaccgc
    30601 ttcggacgtt attccaaata tattatccaa gaacgtgcac tgcctgatat ccgtgatgga
    30661 ttgaagccag tgcaacgccg gatattattt gccatgaaca aagatggcaa tacgtatgac
    30721 aaaggattcc gtaaatcagc aaaatctgtc ggaaatatca tggggaatta tcatcctcat
    30781 ggtgacatca gtatttatga agcgatggtc cgcatgagcc aagactggaa gttgcgggaa
    30841 gtactgatcg aaatgcacgg gaataacggg agtatggacg gtgatccacc tgctgcgatg
    30901 cgttatactg aagccagatt atccaagtta agtggagaga tgctagcaga tatcgagaaa
    30961 gaaacagtcg atctcgtgtg gaattttgat gatacagaaa aagaaccaac agtccttcca
    31021 gctcgatacc caaaccttct cgtcaatgga tcgacaggta tatctgctgg atatgcaaca
    31081 gaaatcccga ctcataactt agctgaagtg atcgatggca caatctatat gatcgatcat
    31141 ccacaagcga gccttgaaaa attgatggaa tatattcctg gacctgactt tccaacagga
    31201 gggatcttgc aaggaaaaga tgaaatcaaa aaagcttatg aaacaggacg aggaaaagtt
    31261 attcttcgtt cgaaaacaaa gatagaggca atgaagggta ataaacagca aatcgtgatc
    31321 acagaaatcc catatgaagt aaataaagcg accttggtga aaaaaatgga tgagatccgt
    31381 ttgaataaga aaatcgatgg aatagctgaa gtacgagatg aaagtgatag aacaggtctg
    31441 caaattgtcg tcgaattgaa aaaagacgcc aatgctcaag gaattttgaa ttatttgttc
    31501 aaaaacactg agctacagat caattacaat ttcaatatgg tcgctatcga ccatatgact
    31561 ccgcatcaag ttggactgaa agacatttta agaagttata tcgagcatcg aaagcaagtc
    31621 ataacaaaac gtagtcaatt cgatttagcc aaagctcaaa aaagacagca tatcgtagaa
    31681 ggattgatga aagctttatc gattctggat gaagtaatcg caacgattcg tgaaagtaaa
    31741 gacaaaaaag acgccaaaaa gaatttagtc gacgtctttc aatttacaga agaacaagca
    31801 gaagcaattg tcacattgca attataccgt ttgacgaaca cggatatcac agagcttcaa
    31861 aaggaatccg aaagcttgat tgcgcaaatc acagagttga ataaaatcct ttcaaatgac
    31921 aaagagcttt tctctgttat gaaaaaagaa ttgcgagaag tgaaaaaaaa ttattcttcc
    31981 gctcgtctaa cgacaatcga agacgaaatc gaagaaatca aaattgatac gcaagtctta
    32041 gtggcacaag aagacgtaat tgtcagtgtg acgcgagaag gctatgtgaa gcgaacaagc
    32101 cttcgttctt atagtgcttc caaaccagaa gaaatcggga tgcgagaagg cgactacttg
    32161 ctatactcag gtgaattgag tacattggac catgttcttc tgatcacaaa taaagcaaat
    32221 gtgatctacc gccctgtcca tgaactaccc gatttgaaat ggaaagatgc tggtgagcac
    32281 atttctcaaa caatctccaa tctgtctgta gacgaatcga ttttagctgt tttcccatat
    32341 caaaaaattc aagcagagaa aacatttgta ttcatcagca agaatggatt gatcaagcaa
    32401 acacgaatga cagagttcga accatggcgc acctataaga gccgtccgct cagctgtatg
    32461 aagctaaagg cggaagaaga tgaactgatt gctgtgtatc tgaaagaaga tcagccaggc
    32521 ttagatgttt tcttagtaac gcatcaagga atgggtttgc gctatccttt aacagatgtt
    32581 cccgttgttg gagcaaaggc agctggagtg aagtctatga atttgaaaga tggagatagg
    32641 attatcaacg ggctgcttgt gttagcagaa ggtgatacgc cgatcgtaat cgttactcag
    32701 cgaggagctg ttaaacgcat gcttgctcaa gaaatcagcc aaacttcacg tgcgaagcgg
    32761 ggagtgacgg tcatgcgtga gctgaaaaaa aatccgcacc gtattatcta tatgtcggaa
    32821 ggaagatcaa aagaaataac cttgatgaat caaaaagggc agcagttaac gattgaccca
    32881 actgatttcc ctataggtga tcgaacatcg aatggatcat ttgcgatgga tgagaaaaaa
    32941 ggtggagaag tcatcgaagt tatcgatgct cctgagattt tcatcgagtc gtaactgttg
    33001 tagtatttta atgaagagac gccatctgta ttaatacagg tggcgtctct ttttcattca
    33061 tttttaataa atccttatac gtttgcaaaa aaagatgaaa gtgttcacaa tgcttaaatg
    33121 ttggtatgtc aacgttgatt taaatatatg taaataaaac ataaaaattg ttaaataaaa
    33181 aacaagaaaa cccttgcaaa gatagggtgc tgtgttatac taatcacgta aaaactgtta
    33241 cataaaacag aaatttagga ggtccataca atggagcaat ggaatggatt taaaggtacc
    33301 aaatggaaag aaggcgtaga cactagagac tttattcaaa ataactacac tgaatatcgc
    33361 ggtgatgaca gctttttgga aggcccaaca gaagcaacag aaaaattatg ggatgaattg
    33421 caaaagttaa atgatatcca attcgagcgt aacggtgtct atgatatgga cacagaaatc
    33481 gtatcaacta ttacttcaca cgatgcaggc tatttggata aagatttgga aaaaatcgtc
    33541 ggtctacaga cagacaaacc tttgaaacaa gcattcatgc cgttcggcgg aatcaatatg
    33601 gctaacaatg cgctaaaaag caatggctat acaccaaacg atgaattgac acatattttc
    33661 actgactggc gcaaaacaca taatcaaggt gtatttgacg cttatactgc tgaaatgcgt
    33721 gctgctcgta aaaacaaaat cattacaggg cttccagacg cttacggtcg cggacgtatc
    33781 atcggtgact atcgtcgtgt ggcattgtat ggaatcgact atttgatgga acaaaagaaa
    33841 aaagatcatg atatgactgg ttatcataca atgagtgaag aagtgattcg tttacgtgaa
    33901 gaaatcactg aacaatatcg tgcattagcg caaatgaaag aaatggctgc gaaatatggc
    33961 tatgatattt ctaaaccagc tgcaaatgca aaagaagctg tccaatggct atacttcgga
    34021 tatttagcag caatcaaatc acaaaatggt gctgcgatgt caatcggacg tatctcagca
    34081 ttccttgata tctatatcca acgtgatttg gataatggag taatcacaga aaaagaagca
    34141 caagaattga tcgaccactt agtaatgaaa ttacgtatgg tcaaattcgc gcgtacacct
    34201 gaatataacc aattattctc aggattccct atctgggcta ctttatccat tgcaggtatg
    34261 ggattagatg gtcgttcatt agttacaaag aatgatttcc gtctgcttca tacattaaca
    34321 aatatgggac cttcaccaga accaaacttg actgttttgt attctgaaca ccttccagaa
    34381 ggattcagaa catatgctag cagaatcgct atcgaaagtt cttcgattca attcgaaaat
    34441 gataatcagc ttcgtgaaca atggggttct gatgattgtg cgattgcttg ctgtgtatca
    34501 ggaacagttg tcggaaaaga catgcaattc tttggcgctc gtgctaactt ggctaaaaca
    34561 ctattatatg ccatcaatgg cggagtcgat gaagtgactg gcgcccaagt tggaccagaa
    34621 tatcgtccaa tcacatcaga aatactagac tttgaagaag tgaaacataa cttcatgaat
    34681 atgatggatt ggttagcaga actatatgtc aatacgttga acatcattca ttatatgcat
    34741 gataaatatt cttatgaagc agctcagctg gctttgatgg attctgactt gcaacgcaca
    34801 tttgctacag gtattgctgg gatctctcat gcggcagaca gcttgtcagc gatcaaatat
    34861 gcaaaagtaa aagcaatccg taatgaaaaa ggaatagcag ttgattttga agtggatggc
    34921 gacttcccta aatacggaaa tgatgatgac cgtgcagatg aattagtttc atggatcttg
    34981 gaatacttca tgggacaaat caaacgtcat aaaacttacc gcaactcaaa accaacaact
    35041 tcattattga cgattacttc aaatgttgtt tacggtaaaa atacaggaaa tactcctgat
    35101 ggccgtgaag ctggaaaacc acttgcgcca ggagcaaatc caagttacaa tgcggaacaa
    35161 agtgggttat tagctagcct gaactcaaca gctaaaatga attacggctg tgcattggat
    35221 ggaatttcaa atacccaaac aatcaatcct tcaggtcttg gaaaagaaca agatacaaga
    35281 atcgaaaact tgcgtaatgt cttagatgga tacttctcaa aaggagctta tcatttgaat
    35341 gtcaatgtat tcagtaatga tttattgcgt gatgcaatgg aaaatccaat gaaatatccg
    35401 aacttgacga tccgggtatc tggttatgca gttaaattcc gtgacttgac aagagaacaa
    35461 caattagatg tcttgatgag aacttcacac gacagaatgt aaaaagttcg tgaaaaaagt
    35521 ttttcgactt agcgtcgaaa ggacgttgaa tagccatcgc atcaaaatcg aataatcagt
    35581 atgcttattt gaaagaaacg atttacaggg gcaggacttg tatgttccgt ccctgtaaat
    35641 tttacacata acgaagcggc aattgcgaaa aattttgttc agaaagcttc gcttcgacag
    35701 ctaacttgta cttaaaatga aatcaaagaa aagatgtgaa cttaaatgga agaaaaaaca
    35761 atcggctatg ttcattctat cgaaactttc ggttcagtag acggacctgg actgcgcttt
    35821 gtcgtgttta tgcaaggatg ccgcatgcgt tgccaatttt gtcacaatcc agatacttgg
    35881 aatattggcg gagggaaaga atacacagca gatgaacttt tagataaagc agaacgcttc
    35941 agaccttact ggggagataa aggtggtatt actgttagtg gtggagaacc tctattgcag
    36001 atcgattttt tgatcgaact atttaaaaaa gcaaaagagc ggaagatgca tactacattg
    36061 gatacatgcg gaaaaccttt tacgtatgaa gaacctttct tttcacgttt tcaagaattg
    36121 atgaagtata cagatttact gttatttgac atcaaacaca tcgataatga agagcataaa
    36181 aaactaacgc attgggacaa tgaaaatatt ttagaaatgg ctcaatattt gtcaaaaatc
    36241 aacaaaccgg tttggattcg ccatgtacta gttcctgagc gaagtgatta tgatgaatat
    36301 ttgatccgac tagacaactt tattcaaacc ttgtcaaatg tagacagagt agagattctt
    36361 ccttatcata cgatgggaaa atacaagtgg gaaacacttg gtttgaaata tccattagaa
    36421 gggatcgaac cacctacaaa agaacgtgtc gaaaatgcta aacgattgct tcatacagaa
    36481 gagtatacaa aatatttaac gcgataggtc gcatcggaaa gaagataagt attgcttctt
    36541 tccgtttttt tgctattatt aaataggaga aatcacaaag gagcgaatga catgtcaaaa
    36601 attttagttt ttggtcacca aaatccagat acagatgcaa tcggggcagc cattgcgttt
    36661 tcacacttgc aaaatgaatt aggtaaagaa acagaagcag ttgctctagg tacacctaat
    36721 gaagaaacac aatacgcatt agaccacttt cagctatctg caccacgagt agtagagtca
    36781 gctaaagcag aaaatgcaga tgtcatgctt gtggatcata atgaattcca acaaagtatt
    36841 tcagatatca gcgaagtaaa tattttagct gtagtagacc accatcgtat tgcaaacttt
    36901 gaaacagcta atccattgta ctatcgtgca gaaccagttg gatgtacaag tacgattatt
    36961 ttaaaactat ataaagaaaa ccaagtaaca attcctaaag aaatcgcagg aatcatgctc
    37021 tcagctatca tttcagatac attgttgttc aaatcaccaa catgtacgcc tgaagatgaa
    37081 gcagctgcaa aagaacttgc agcaatcgct gaagtcgatc taaacactta tggacttgaa
    37141 atgttgaaag caggaacaaa tctaagtgat aaatcagctg cggttcttct tgatttggat
    37201 gcaaaaagtt tcccaatggg cagttccaac gttcgtatcg ctcaagtcaa tacagtggac
    37261 cttaatgaag tgatggatcg acaagcagag ctagaagcag caatggaaga tgaaatgaaa
    37321 gcaaatggct acgatctgtt cgtattagtt gtcacaaaca tcttagacag tgattcagaa
    37381 ttacttgttg ctggtaaagg aaaagaaaaa gtagaagaag ctttccaaac aactttgacc
    37441 aacaaccgtg ctttgcttaa aggtgtcgtt tcacgtaaaa aacaagtcgt acctcaattg
    37501 acggctgtat ttagctaatc aaatggtagt atgaagcatt caaaatgaat ggataagcga
    37561 ttgatataaa aagaaacata gaacatacta aaggccgaag aaatggagga gaataacagt
    37621 caattatgac tcttgttctt cctccttttt acgtaaaagc cttttaagta aaataaaacg
    37681 gatagaaaag agaacatata tgaactatta ttcaaaaaat aaggaaaact tttatcaaaa
    37741 actgaccgat gatccgcttt tttcttcatt gaccgattat ctatatgaac atcgagaaca
    37801 agaaacgatt ctaagagaat tgaaaaaaga attttcgcaa aataaatttt cccattttct
    37861 tgatttattg atcgatgcag gattaatcaa gagggaagaa cgaagatatc atttgaactt
    37921 tccaatattt gatcctaaag attacttgca acaagccact tcggctgctg aaaccatagc
    37981 tgaacaattg aagagactct ctgttgatga acaaaaatta gcgatgggag aagttatttg
    38041 ggcgtattgt ttcgaagatg aacggaaaga agcgtatttt tatggagtaa gaaacagccg
    38101 agagacagaa ttgctgagga caactgcagg aaatgagaag taccgtttta tcacactttc
    38161 ctctatagaa cacttcccgc ttactttggc taattacttt tttgtacaga agaatcagct
    38221 tcctgtaacg aaggcattca aagaattagc cgaacttatt ggagacgtaa atgaatcgta
    38281 cttttttgat caaatagaag ttatcgttga caggatacgt aagaataaat ataaaaatcg
    38341 ccggcctagt attttccatc agtctctact tgtgacgaat actataaagg aagaagaatc
    38401 attcacatta gaattaccta ttgtcgaaaa aaacaatttt gagattgaat taccaacatt
    38461 ggatccttca ttgacaatgg aggaaatggc ctttcttaaa cgacaaatct tttctgagct
    38521 gagcaagaaa tttataccgc atgcattttc ttatatcaaa gaatatggaa cagttttagt
    38581 gagtaaaacc taagagagca gtaagcaaaa attatactga ctcttgcagg aggagccttt
    38641 ctcttccttt atggttaaaa gaattatttg agtattttgc ctatctacca cctattagat
    38701 tcactacatg gtctggaaac aaaggaatgc aaaaaaatgg tgagaaatgt ggaatgacaa
    38761 aggaagtagt gataagaaaa gttagatttt taaataatca atattatgat tcagtcaagt
    38821 atggcatttt atgggaagaa ctagctgatt agattaggaa gtccatttga taatccagaa
    38881 tcactaagaa acgaatggcg agtcattaat aatttatcca atcttgggtt attcttttag
    38941 attgaagtgt ttaaaactaa aaaagcattt atgaagtcgt aatagtcagg cttcaaaatg
    39001 ctttttattt tgtttgtttt ttctttgcca cataaataca cctagactga cgatgaagag
    39061 catatccaac agatttcctg cgacttggat cgtcgaaggg ttggtcagtg gcattaaagc
    39121 aaggacaaaa aaggaaaaca agctgtaaat aaaacaggtg acaggaacta atcgaaagaa
    39181 gagcggacat ttcaattggc taaaaatgag tgaaaaaata aaataagtaa aaatggataa
    39241 aatcacgact aaaccattca tgataaagaa gaaaagcgta ttgtgattaa acgaataaaa
    39301 aagaattgct aaaaaagaaa acgttttaaa tgcaatcaat acgcttgaag cttcgtttaa
    39361 cgtaccagga tgtcgatgaa aaaaataggc accgaaataa acagaaaaca gtaagccgca
    39421 aagagaagac aaaatcaaaa aaaacggatt ttcttcggct tctgtgatat cagaatgatc
    39481 caaaagcaac cagcctaatg cactagaagg cgcatgtgag gtcttaaggt atgaataaca
    39541 tagaaaaaat aagatcgtca aagttgcaaa aaaagagcct aaatgtaaaa aattagtggt
    39601 tctacgttga atttccataa tatctccaaa ttaa
//
LOCUS       DAZUJR010000016        37729 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.016, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000016 DAZUJR010000000
VERSION     DAZUJR010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37729
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.016"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            476..1339
                     /locus_tag="ACG804_000784"
     CDS             476..1339
                     /locus_tag="ACG804_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFS4831733.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1468..3090)
                     /locus_tag="ACG804_000785"
     CDS             complement(1468..3090)
                     /locus_tag="ACG804_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFS4831734.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            3339..3860
                     /locus_tag="ACG804_000786"
     CDS             3339..3860
                     /locus_tag="ACG804_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HFS4831735.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="ACG804_000787"
     CDS             complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="ACG804_000787"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047112 - pyruvate oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HFS4831736.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5941..6759
                     /locus_tag="ACG804_000788"
     CDS             5941..6759
                     /locus_tag="ACG804_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HFS4831737.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKHHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6862..7059)
                     /locus_tag="ACG804_000789"
     CDS             complement(6862..7059)
                     /locus_tag="ACG804_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831738.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            7228..7806
                     /locus_tag="ACG804_000790"
     CDS             7228..7806
                     /locus_tag="ACG804_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HFS4831739.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            7901..8038
                     /locus_tag="ACG804_000791"
     CDS             7901..8038
                     /locus_tag="ACG804_000791"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831740.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(8851..9354)
                     /locus_tag="ACG804_000792"
     CDS             complement(8851..9354)
                     /locus_tag="ACG804_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFS4831741.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            9713..10738
                     /locus_tag="ACG804_000793"
     CDS             9713..10738
                     /locus_tag="ACG804_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFS4831742.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            11061..11939
                     /locus_tag="ACG804_000794"
     CDS             11061..11939
                     /locus_tag="ACG804_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase domain-containing protein"
                     /protein_id="HFS4831743.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            12415..12531
                     /locus_tag="ACG804_000795"
     CDS             12415..12531
                     /locus_tag="ACG804_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HFS4831744.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            13459..13797
                     /locus_tag="ACG804_000796"
     CDS             13459..13797
                     /locus_tag="ACG804_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831745.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            13891..14121
                     /locus_tag="ACG804_000797"
     CDS             13891..14121
                     /locus_tag="ACG804_000797"
                     /inference="COORDINATES: protein motif:HMM:NF042636.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6568 family protein"
                     /protein_id="HFS4831746.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            14521..14892
                     /locus_tag="ACG804_000798"
     CDS             14521..14892
                     /locus_tag="ACG804_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HFS4831747.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(15166..15858)
                     /locus_tag="ACG804_000799"
     CDS             complement(15166..15858)
                     /locus_tag="ACG804_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFS4831748.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(15861..16646)
                     /locus_tag="ACG804_000800"
     CDS             complement(15861..16646)
                     /locus_tag="ACG804_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFS4831749.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            16883..18283
                     /gene="lacG"
                     /locus_tag="ACG804_000801"
     CDS             16883..18283
                     /gene="lacG"
                     /locus_tag="ACG804_000801"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HFS4831750.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            18308..18625
                     /locus_tag="ACG804_000802"
     CDS             18308..18625
                     /locus_tag="ACG804_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFS4831751.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            18638..20311
                     /locus_tag="ACG804_000803"
     CDS             18638..20311
                     /locus_tag="ACG804_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HFS4831752.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            20325..21956
                     /locus_tag="ACG804_000804"
     CDS             20325..21956
                     /locus_tag="ACG804_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinogalactan endo-beta-1,4-galactanase"
                     /protein_id="HFS4831753.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(22447..24012)
                     /gene="guaA"
                     /locus_tag="ACG804_000805"
     CDS             complement(22447..24012)
                     /gene="guaA"
                     /locus_tag="ACG804_000805"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HFS4831754.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(24071..24994)
                     /gene="coaA"
                     /locus_tag="ACG804_000806"
     CDS             complement(24071..24994)
                     /gene="coaA"
                     /locus_tag="ACG804_000806"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HFS4831755.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            25190..25795
                     /locus_tag="ACG804_000807"
     CDS             25190..25795
                     /locus_tag="ACG804_000807"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFS4831756.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            26103..27119
                     /locus_tag="ACG804_000808"
     CDS             26103..27119
                     /locus_tag="ACG804_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4831757.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            27260..28561
                     /locus_tag="ACG804_000809"
     CDS             27260..28561
                     /locus_tag="ACG804_000809"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HFS4831758.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            28607..29269
                     /gene="deoC"
                     /locus_tag="ACG804_000810"
     CDS             28607..29269
                     /gene="deoC"
                     /locus_tag="ACG804_000810"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HFS4831759.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            29290..29688
                     /locus_tag="ACG804_000811"
     CDS             29290..29688
                     /locus_tag="ACG804_000811"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HFS4831760.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            29754..30836
                     /locus_tag="ACG804_000812"
     CDS             29754..30836
                     /locus_tag="ACG804_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HFS4831761.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            31048..32610
                     /locus_tag="ACG804_000813"
     CDS             31048..32610
                     /locus_tag="ACG804_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4831762.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            32603..33736
                     /locus_tag="ACG804_000814"
     CDS             32603..33736
                     /locus_tag="ACG804_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4831763.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            33736..34692
                     /locus_tag="ACG804_000815"
     CDS             33736..34692
                     /locus_tag="ACG804_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4831764.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            34791..35957
                     /gene="deoB"
                     /locus_tag="ACG804_000816"
     CDS             34791..35957
                     /gene="deoB"
                     /locus_tag="ACG804_000816"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HFS4831765.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            35981..36799
                     /locus_tag="ACG804_000817"
     CDS             35981..36799
                     /locus_tag="ACG804_000817"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFS4831766.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            36816..37523
                     /gene="deoD"
                     /locus_tag="ACG804_000818"
     CDS             36816..37523
                     /gene="deoD"
                     /locus_tag="ACG804_000818"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFS4831767.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
BASE COUNT        11762 a         6608 c         7962 g        11397 t
ORIGIN      
        1 ccactaaacg gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat
       61 gagaagctgt tttttgaaat tgttccttgt gactcggagc taaacggcag gctcacaacc
      121 tcttggtaaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa cggcaaaata
      181 tgaggaacta ttttttccgt ttttttctct aatactcagg tcaaaacgct gatttcacaa
      241 cctctgattc acggtgttcc agaagtagct tctacggaaa taagccgaaa tttcacaaaa
      301 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
      361 aacctcttat tttgattaga acttgcgaaa ataaaccggt taaagtgtgt ctagcgcaag
      421 agatttgcta taatagacga taagggtaaa atgtaacgag aaggggttga aaaatgtgta
      481 tcaaattgta acagattctt gttgtgatct gccataccat gtattagcaa aagaaaaagt
      541 tgatttttta tcaatgaatc tccaattgaa tgatcaagag ttagtagatg acctcggaaa
      601 gacattcaat tatgaccgct acatgaatca gctgaaaaat ggtgcgatgc ctacgacatc
      661 acaaatcaat gttggccgat atttagaatt tttccgttct tatgcggaaa aacagattcc
      721 tgttttatat gtggcttttt ccagtggatt aagcggctct tacagtagtg cgcttcaagc
      781 ggttgaattg ctgaaggaag aatatgaaga ccctgagatc tatgtttttg atacaaaagc
      841 tgcaagtatt ggggaagggc ttttagtatt ggaagctgta agattgaaaa aagaaggtaa
      901 aagcatcgaa gaaaccctag agtggctgga aagtaattat ttgaaagtcc attcatgggt
      961 aacagtagac gatctgaaat atctagaacg aggcggtagg atttccaaag caagtgctac
     1021 tcttggcagt ctattgagtg taaagcctat tattacggtg gataaagaag gaaggctgac
     1081 gaatgttgac aaagttcgag gaagaaacaa gtcgatccag acaatcgtca atgagacggt
     1141 aaaaacaatc gttgcaccac ttgatcaaat cgtttatgtg gcttacgctg gggatctaga
     1201 gagcgcggag aaggcaaaac ggcttttgga agagcagata aagatgaaag atgtgaagct
     1261 ttatccctta ggaccaacga tcgccagtca cacaggctat ggctgtatcg cgattttttc
     1321 gatgggaatc agtcgataaa agcagtaact cattctgtaa aaaagcccag aaattgattg
     1381 taacaaaaac agcgactctt aaaagataga tgagcatcct atctcttaga ggtcgctgtt
     1441 tttttatttt ttaagctaaa taggccatta tgcccataac tcgttcaatt gtttttgaat
     1501 atctgcattt tccaaaaatt catcatatgt cgtatcagct cgatcgatca cacctttatc
     1561 cgaaacggca atgatgcggt ttgccaatgt ttggataaat tgatggtcat gtgacgcaaa
     1621 taagattgag ccagtaaatg ccatcaagcc gtcattcaat gctgtgattg attctaagtc
     1681 taaatggttc gttggatcat ctaatacaag tacgttagct ttcgaaagca tcatttttga
     1741 aagcatgcaa cggactttct ctccaccaga taaaacattc actggtttca atacttcttc
     1801 accagaaaac aacattcttc ctaagaagct tcttaagaag gtgttatcat cttcttcttt
     1861 acttgcatat tgacgcaacc agtctaaaat cgttagatca gtatcgaatt ctttcgttgt
     1921 atcctttggt aaataagaat tacttgttgt cacaccccaa cgtactgttc cagtatctgg
     1981 cgtaatttca cccatgataa ctttgaatag cgttgttgtt gttatatcat tttctgcgac
     2041 gaaagcgacc ttgtcttctt tgctcaaatt aaaagatata tcatctaaaa ttttctttcc
     2101 atcaatcgtt acacttacat tttctacctg caataagtcg tttccaatct cacgttcagg
     2161 tttgaatcca acgaatggat aacgtctaga agaaggttgg atatcgtcta aagtaatttt
     2221 ttcaagcatt tttttacgtg aagttgcttg ttttgatttt gatgcattcg cactaaagcg
     2281 ggcaataaat tcttggagtt ctttgatttg ttcttctttt ttggcatttg cgtttgcttg
     2341 aagtttagcc gctagttgac tagattccaa ccaaaaatca taatttccta cataaagttt
     2401 gattttacca aaatctagat ccgccatatg tgtacatact ttgttcaaaa agtgacggtc
     2461 atgggataca acgatcacag tattttcaaa attgatcaaa aattcttcca gccaattgat
     2521 cgattggata tccagaccgt ttgttggttc gtctagcaaa agaacatcag gtttaccaaa
     2581 tagtgtttgt gctaataaca cttttacctt ttgtccacca gttaattcac tcatttgctg
     2641 atggtgcaat tcttcaggga tgttcagacc ttgcagtaaa acagctgctt ctggttcagc
     2701 ttcccatcca ttaagctcag caaattctcc ttctaattca gctgctcgaa taccatcttc
     2761 gtcagtgaaa tcctctttca tgtaaatcgc atctttttct ttcagcactt catacagacg
     2821 cttgtgtccc atgatgactg tttcaagtac agtatagtct tcatagtcgt aatggttctg
     2881 tttcaatacg gccatccgtt catctggtcc catagtaacg gaacctgtgg aaggctgcag
     2941 atcccctgat aacactttaa ggaacgttga tttacctgca ccatttgcac caatcaagcc
     3001 atagcagttt ccgggggtaa atttaatatt cacatcatca aatagtttgc ggtctgaaaa
     3061 gtgcaaactc acatcattta cagtaatcaa tttttttcct cacttttatc attattagtt
     3121 ttgacaagtc ttatagaatt atatagggga aaggtaaaag attcaaggca atcgaacatt
     3181 ctttgtgttt cacgtgaaac agaatgaaaa aaataaaaat aaaagcggag cgaaaatagc
     3241 tactatagga tttattagtt tgcaacagca taatttttga cgttatttat aagagggagt
     3301 actataaaac tgtaaaagaa atgaaagaag gattgaaaat ggatgaaaaa agaaccatcg
     3361 actggggctc attgattttg ggaattttat ttgtacttgt ctcattgtta tcatttcaag
     3421 accctgtcgg aaatttagtt gcaattgtag tagtctttgc gatttttgcc tttattaaag
     3481 ggatatttga actgtttgta cggaacagat taaaagagct aacaggatat aaaggaaaga
     3541 tgcccttaat aatcgggatc atcgatattc tagttggcgt ctttttctta ttcaatattg
     3601 gtgcaggagt cgcagcattg ccttttgttt ttgcagtatg gtttattgct gattcagttt
     3661 tagcgttatt tactgctgac ttggcaagag gagtaagtga aggatattat tggtttacga
     3721 tcatcgtcaa tattttagga attttattag gaattttctt attgtttaat ccaatttctt
     3781 ctgcgttgac attaagcttt ttagttggat tctattttat gttatttggt atcacacata
     3841 tcgtctatgc atttagataa gtaaaatcaa acaaataaaa aagccggctt ccgattacag
     3901 ttttactgtt gtaattggaa gccggctttt ttatcatgga caaatatgca cgaggtgatt
     3961 tttaggtgtc gagacaaatt tatgcaaaaa tgtgagaagc tatatacaca aattttatct
     4021 taatactcga agcatagcgc agttgtcaca acctcttttc atataattca ttcaatactg
     4081 gcaaatcatg gacttcatat ttttctttga atgcttggat ttcttcttca gaatattttc
     4141 ttggatctaa atgcagatct tctactggca atgggcgctt gttattgatc ttcacatcga
     4201 ttactacagg acgatctgat tttgcagctg catcaaaggc aaatcgaagt tgcgagtatt
     4261 ctgtgactgt aaagctattt gccccgagcg cttctccaac tttaccgaaa tctgcatctt
     4321 ctaaaaatac accaaatttc ttttgttccg tatcttcttg ttctgcttcg atgaaaccaa
     4381 aagaatcatt cgaaaagaca acattaataa ttggaagctg atatttgact tgtgtaatga
     4441 tatcttgcat gaccatagca aacccgccat caccacttaa ggtaaatact tgtttttctg
     4501 ggtagcttag ttgtgcggca attcctcctg gcacaccatt acccatagtt gcgaaccatc
     4561 cagatgtcgt atgtttttgt ttaccgttca tattcaataa acgaatagaa tggatagtcg
     4621 tgttaccgac atctgtgacg aaaatcgcat cgtcttcagc aatacgattg atttctttat
     4681 agacagcctc tggacgaatc ggttcttcct ctcgatcttc aaaagatttc aaccaattta
     4741 cccatttttc tttattttct tgatttgcta ggtaccagct atcagcaggg cgagcatccc
     4801 ctaactcgac aagtctttgc aaagctgtgt ttgcatcacc gaggatcgac aaagatgttt
     4861 catggcgtcg tccaaatttt gacgcatcga tatcgatttg gataaattca gcagttggat
     4921 taaaaaatgc acgtccaaat gggaagtcgc taccgacaaa taagatcaga tcggcttctg
     4981 ccaatgcttc atttccgggt ttagtagcga cacgtccagc aaaaccaaga aagttttcat
     5041 aatcatcagg aataattcct tttgctagaa cggaagcgac aacaggaact gaaaaatgtt
     5101 ctgagaattc tttgatttgc ggaaatccgt ttcgcgttcc ttgaccaaca taaagaactg
     5161 gtttttttgc tttttcaaga taaggcaaag cagctagcaa atctttttct tctggtaata
     5221 tcacacttgt tttgtgagtg tgagcggtgg agaaaggttg ttcgtcaatt tcttcaaaac
     5281 caagatcaac agggatagtc acgatagcca cgcctttatg ctcataggcg gctttaatgg
     5341 cttcatctac tacatgcgga agactttgtg gtgtcatgac tgtacgattg tatacgctaa
     5401 catctgcgaa aataggattt tcatttagtt cctggaaaga gttatagttc atggatgtag
     5461 aagcaacttg tcctaagaac gctactagag gcacatggtc catctgtgca tcatacaaac
     5521 cattgatcaa atgtgtcgca ccaggtcctg cagagccgaa gacagcgccg actttccccg
     5581 ttaattttgc atctgcagcg gctgcgagtg cgccgacttc ttcatgacga acttgaatgt
     5641 agttgatttc ggttttttct tgatatagcg catccataat tgaattgaaa gatcctccgg
     5701 gaatgccgta aatatggtcg ataccccagc tttcaagaac ttttaccatt gcgattcctg
     5761 cattgatttt tgacatggtg tttcactcct ttagcaatga tgatacataa attttttgta
     5821 tctagagtat agaacttttt atcgaaaatc ccaactaatt cgtcttttca caaaaatgta
     5881 gtcatgtttt tgggaatatg ctagagtagt acatagatag attcaagaga ggggaatggc
     5941 atggttgaat ggctattgag acttgaacct tggcagcaag cacttgctgg gacagctttt
     6001 acttatttta tgacagctct tggtgccggg ttggtttttt tctttaaaga aatcaaaaaa
     6061 gaagtgctaa acttgatgtt aggatttgct tctggtgtca tgattgctgc aagtttttgg
     6121 tctttgttag atccggctat tacaaaagca gaagaaaatg gagatattgc ttggctagtt
     6181 gtaagtattg ggtttggttt aggcggtgtg tttttatata tggcagataa aacactgccc
     6241 catatgcatt ttggaccaca acatgaagca gaaggattgc ctacccattt aaaacggacg
     6301 atcttgcttg ttttttctat tacattgcat aacattcctg aaggtttagc cgtgggggta
     6361 gcattcggtg cagcagcaac tgcggataat ccgacagccg ctatattagc cgctgtttcg
     6421 gtggcgctag gtattggtat ccaaaacttc ccagaaggag cagctgtatc aatcccgttg
     6481 cgacaagaag gtctgagtcg taaaaaggcc tttgtttacg gacaagcttc tggaatcgtt
     6541 gaaccaattg ctggagtgat tggagcgcta ctagtaacga aagtggagct gctgcttcct
     6601 tatgcacttg cttttgccgc aggagcaatg atttatgtcg tggtggaaga attgatccct
     6661 gaagcacagc agacattgtc cagcaaacat cattttgcag tttttggcgt catgagtgga
     6721 tttatcatta tgatgatttt ggatgtggca ttaggataaa taaaaaaaat atatatgata
     6781 tatcaaatag ggccgcgaac ttatatcgcg accctatttt tttagtaagt tatatcataa
     6841 tgaagtgaat ggtatcatac attaataata gttttttcta tgtgtatttc ctttgatcca
     6901 gcgaacaagc cagatgataa gtgcgattgg gattagaact ttgaccgcaa accataaaag
     6961 cccgcttagg acactgacaa aaagactgat gacgaagcta gctgcaatta gcactaaaag
     7021 aaccatgaag atatttaaga acatattttt ttgacgcata caaaaccctc ctcttgttca
     7081 ttctttacta tagaaaaagt ataacaggga ttgtttaaaa acacctccaa ctgaagactg
     7141 atttttactt catctactta aatgatcaaa caattgcttt ttctctggtt tatcatctaa
     7201 aatagagcgg aaaaggagga gaatatcatg cctaaaaatc gtcttgaagc atttacagat
     7261 gctgtaatcg cgattatcat gactatttta gttttagaac ttcatgaacc taacggagac
     7321 acgtgggagg cgctcgctgc attaggttac cgatttttta tctatattgt cagttttatc
     7381 attttagcga tttattggaa caatcatcat catttatttc aagttgtaca taagataaat
     7441 ggacgggtct tatgggcgaa cagtttcttt gtttttgcgc tttcgctttt tccgtttgca
     7501 acttcatgga tcagtgagta catcaatagc ctggctccag aaatgactta tggttttgtt
     7561 accttgaccg ctaatattgc gtattatatc ttggcaaaag aacttgtcaa agcaaataaa
     7621 ggccacgaga aagcattgaa ggcgatgttg aataattaca agaaatcgta tctatcgatt
     7681 ggtttgaatg tgttaggaat tgtcttaggg tatttagtag cgccagtagc cgtgctgatc
     7741 gcaaacatcg tgattctagc tgcttggatc atcccaagtc gtaccatcga atcacaatat
     7801 cggtaaaatg atccgtgttt aaaatttaag agaaaaatat agaaaaaata aataaacgat
     7861 caaatatccg agtgatacta gtattcaaag agggatgcag atggatcaaa aaagaattca
     7921 tgtaggactg attactagtt ttgtcacgat gcttatttat ttggatcaag gtcatttgac
     7981 ttggacagta gttggtgtcg taggattttt gacattattc acagcaataa aaaaataaac
     8041 atctttatgt aatctgatgt tctatctatt taagaaaagc atgtttacag cagtatgatt
     8101 ctgttgtaaa cgtgttttta tttgtggaaa atttaatttt tagaaaagtg tatcgaaaaa
     8161 tagatagtta gtttttccac agtggataac ttcgtaagag ataaaaataa aaaattagtc
     8221 aaagaagggc gtatagattt cttttgatag gagatataca acagaaatga ataaatatta
     8281 acgtgttttc aaacagtata aaacggtgtg gtttttggaa taaaaaaata acatatctca
     8341 ttttacactt ttgttatttt atacttaaaa aataacgaca cagaaaatac cgtgtctcag
     8401 atttctctac tacttctaaa aactactgtt tttttccttt gaaatgcctt caaaaagtag
     8461 gatcaggcag aatatactgg cagaatcaag gagaagggag cctaaataag gagaaaaacc
     8521 atagaaaata taaagtaatt acttataaaa caagcttttt atagaaaaat aatatacctg
     8581 agtagggtat aaattaagac ggaattcctt tctagattga gatattgact aggaagaatg
     8641 ttaagatttt aagcctttaa gctaaaaaaa aacccttttt gttaaataag gggaatatag
     8701 cctgtcagtt tcaaactgca agtcgtcctg ctgcaataat atagtagatt agagatgaaa
     8761 atagattttt ttaaaccaat gactgaataa aaagaccgtc atagatacac attggaatgt
     8821 gtctattacg gtcttttttt acgaacgatt ttattgaaga cggacagttc gggtcaaaaa
     8881 taaaaaagct acgatcagaa ataagaataa aatgtatccc aaaataatgg ctagacggtc
     8941 taacttattt gtcgatagat gtttgtttag aagttgatag gcccataaac ctatcagtcc
     9001 tcctgttgta ttagttatca aatcagtgat gtccgctacg ccaataccga ataggaattg
     9061 aatcaattct gccaagaagc ttacaaggaa aataatccct aattttttag aaaaagaaag
     9121 tctcttgaaa ttgacattca aaagcacccc aaaaggaaaa aagacaatca agttataagt
     9181 ggtctcacgt aataccgtcg tattttcaaa agaaaaagta gaaaaaggga cgagattgac
     9241 attgctgtaa gaataagtga gaaattgtgg aagattaaat gatagcttga ataaaatcaa
     9301 ccataataga aagaataaat aaatccctaa taaaaatttt gatacatacc gcatagacat
     9361 ctcctccatt taaaaagtat accatcgaaa accgctgaaa aatcataaaa aagtatgaag
     9421 tttaaggacc aacgtagtta tcgtacgaaa attagaagct tttttttgtt gggaatccgg
     9481 tttctttaac aaagctaaga tagcgagttg cttggaaaag ttgctatctt ttttctgtca
     9541 aaacgactcg gaatgttcgt tttttgttct aatttctcca agttgtttac tttttgatac
     9601 taagtttatg aaaaatcaag aaatagttgt tatactaggt aatgctgaca aacgggattg
     9661 gcatttcatc ttggttcagc tttttttcca attactagga aggagggata gattgttcaa
     9721 gacttatttt cgtttcaata aaatacaaga taatcctttt cgtatcatga atctgatgct
     9781 acttatcttt attgtattat ggttaggtta cataaatcat gattttttga tttcaagttt
     9841 ttcatcatta gggatcttta cttttttcta ttatcaaaac ataccgatga aatatttgct
     9901 gaaacgtatg tttctgatcg gttgcggact gttggttgct ttcgttttgg ggatcttatc
     9961 gacttatgtt ttatggcttg aaccatttgc cgtagctttg gttgcttttt ccagcagatt
    10021 cgtgttgcga ttattccata tttctaaacc aggtggcttg ttttttgcga tgctttctgc
    10081 catgggaacg agcatgcagc tgccaatcgc tcaattaccg atcgtctcac tttatttttt
    10141 tatgggtgtc gtttttgccc tgattgcggc agtgattaca aaattactgg attcacggcc
    10201 tgagcagaca attgaaaaag caactttaaa agaaagattt cacgaagagc ctttagtgat
    10261 cattgattct gttttctaca gcgctgcctt atttctttcc gtttatgtca gtcacggctt
    10321 gaatctgcat aatccttatt ggttgacctt gtcatgtgca tcgattttgc tagcagaaaa
    10381 cttggatgcg atgaagcatc gacaagtcca atatctgatt ggatcgatgg gtgggttatg
    10441 tgtgtcggca ttcttgtcat ttgtgccgtt tacgcagttg cagaccattt ttctgatcac
    10501 ttttctatat ggaatcgcac aatttctagt tgctagaaat tatgcagttg ctaatatttt
    10561 tcttaatccg atggcgttga tgctatctac acttattcgt ggagcatact tgatttcttt
    10621 gatcgaatat cgttttttag ggatcgtcat aggaagtttc atcggtttag gtgttgcgtg
    10681 ggtaatgacg gttggtttgc aacattattt aacggttgtt cgtcaaaaat tagaatagaa
    10741 ggacaaatat atgtgccaaa agaggttatg acaagatttt tgtcacaacc tctaattcaa
    10801 ggtgttcaaa agccagattc tcagcattaa gtcaaattca cacaaaaatg tggaaaggaa
    10861 ctttcaaaaa aattttatat ttattctatc aaaaaatttt gtttatgatg gtaactgaat
    10921 aaactttcct gagatggtca atgctttcct tgaaagtctt acagatattc tttcttcata
    10981 gaaagtttaa gttttatagt tagtgtacaa taaaagtatg tttataccat atggtgtccg
    11041 gataatcagt catttaaaca atgaggttca aagatatgaa aaggggaaat ttgatgaaga
    11101 aaataagcaa tgaaatccaa attctggcag aaactttaac tcttcccaaa gtcgttatag
    11161 agcaaatgat tgtacaagca aaaaacatcc ttgatgaggt gtttgagcaa tatagtcatg
    11221 aactaatgga tcctaataaa gcaaaggcga ctgcaaagaa aatagacaaa gtctatgaag
    11281 aggaaccttt tgcagcatta gctatttatc tatatgcagc ttctcaaagt tggaaaaaaa
    11341 tttatcaacc attgaagatt ccaagaacta tctatttggc aacaatgaat gcttttacta
    11401 gatttattca tgaacatttc caagtaacag gaagctatcg ctttgaccgt ggtttttgga
    11461 tttggcatta cactagtggc ttgatctttc ggattggtga attggagtac gaaatgacat
    11521 attttccgaa agggtacacg gatctaagat tagaaggaaa gcagtgcctt tctcttcata
    11581 ttccttccga tgcagattta tctcagaata agataagaga tagttacgaa agtgccattc
    11641 gtttttttga actttatttt cctgattacc attaccaagt gatgtacaca gatacttggt
    11701 tactatcacc caatcttact aaatggttga aaaaagagtc aaaaatctgt ctttttgcag
    11761 ccgattatcg attattatca gttgatgaac aggacgatag tggagtccct tggatctttg
    11821 gacgagtaga tgcccaaata catgattatc cagaaagtac gagtttacag cgacaagcaa
    11881 aagagcaatt gcttgcaggc gagcacattg gctctggctt aggtattctt acttcataag
    11941 tttagtactt cgaaatagtt taaaagagcg tgagacaaaa gtaaagaaca cttttgtctc
    12001 acgctctaaa cacgtataaa cggcggaagc agaagcaact ccttcggaaa taagctgaaa
    12061 ttcacaaaaa tttgaaaagc aattttcgtg aatttcttct tatttcttgg agttaaacgc
    12121 ttctgtccca gcctcttttt tagtgttcta tcgaacacac agtacgttca ataggtaaac
    12181 tagctataac aatagatatt aaagttaacg gacaagaggg ccttttttag gtagctaaaa
    12241 cgtaataatg aaaatttatt tccagagata ggagtcaatc agctagtctg atcgactgtt
    12301 ttaacaagtt gactttcatt ttaacttttg ataccattta aaacacaaat cgtaattgtt
    12361 tcgatttgtg ttttttagca tgactacaat caaagaagaa agtgggtcgt ccatatggaa
    12421 aaaacagata tctcaagtgc ataccgccgc ttgaaaagcc caaatatcaa aacacgaaaa
    12481 cgtgcgctga agatcatcaa agatgtgaaa cggaatagtg ggaaaaggta agaagaagga
    12541 aacttaatta aaaaaatagc cgaaaaacgt ttttcggcta ttttcaataa tcggtttttg
    12601 tgtaaggttt ccgaaagaac tgctgttgat tttccatttt taacatatga taaattggta
    12661 gaatctttct tttcaaattg ataccattcc ctaattccag ttatatagtt aactacagaa
    12721 ccacaaagca cgtacgttta taaaagtatt atctgtagtt atttttcaat tccctttcaa
    12781 cctcttattt tgaccagtag tattgatcac tttacctttt aacacctttg ttcgtttttg
    12841 aaacattttt agtcaagaat ggaaacgtaa ctacataatc aaaggttttg cgaaatattt
    12901 catgaaatat ttcatgtaga agcgagcaat acggttgcaa ataaccatta tcgtttaata
    12961 agcagttacg aaagctccca atatctctaa cgttcagctc actccatttc ttttcttcaa
    13021 aaaaatcagt gattcgtatc tctttctatt tgtcgaaaaa gttaacttta aaaagtaacg
    13081 ccgaaaaaat atgcaaaaaa ataaaaaagc agttactatt gctagaataa catcaaggaa
    13141 taataagttt tggttttcag ataatagtcg ataagttgtg tattggaatt ttagatacag
    13201 taataaagta tttttcatga aattttgtga gaatcactat tacaagtatc tttaataaaa
    13261 ttaatggtta aggaggaact taaagtagaa tgtaaatgaa tagttgtagt cagtcgattg
    13321 tgatactaga ctcaaagttg caggaataag tttttcaatt tgtgattgga agataaaaaa
    13381 tgaaaaagaa gggctttttt ttatactttg ttgattgtag tgtttatttt ccctctgttt
    13441 agccaagtaa cattttctat gactcaacca gtttcaagtg aggaacatga taaccttttt
    13501 cgtgctacag aagagtttaa gaaatatcag gaaaatattg ttccggagac tccattagct
    13561 agtgagccaa ttactgatat tgatggaaac caaataggat ggtatataca gtacgaagtt
    13621 atggtggtaa ataatgactc aatagtaaaa aatacagtag gcttagagct aacaccgatt
    13681 gaaaaggtga gttcattgtt aacgtatatt tatactgatg aaagtgacga gactgagatc
    13741 attttaacgg attactcaaa aattgctact gataaaaagt atatattgtg gatgtagaca
    13801 ctagtgaaat actttatgat atagaaattg atgaaaattt actagatgta gcacaagaaa
    13861 tcgatcatca aaagcaggaa gctattcgat atgctggtag aaaagggaaa agaaaatatt
    13921 tattacgtga atgtagcaaa agttagagaa gatgaaaatg agtggaaaga attcaagagt
    13981 cgctactcaa ttaactcgac tccgacattt acagtttaca gagaaggatc gatagaaaaa
    14041 actgtttttt ggactaaaga aagtggaatg tctttagctg aagtagaaga gtttttggat
    14101 tatgttagta tgcaacagta agggagttct tattatgaaa aattttgaca catattatgt
    14161 tattgttttt tcgatatctt tgctgttaat attactaact ttaatgcagt ataaagagta
    14221 tccagagtat tttattttaa cttttgtata tttagtaagt agctacacac ttctatataa
    14281 attcagaagt tcttctagag tttctaaagt ttgtttctta attagcttat tgattctata
    14341 atatttttga tttatatagg aaattaaaaa tattatagaa tcaacactca gagaacgggt
    14401 tggtttttaa tagatttaat aagtactgat aatgaaattt ctcctggttg ggaaaacgaa
    14461 gttggttacc ctgtagaaga attttttcaa gattactttg cggagtatgc cgataggata
    14521 atgagagatt acgtaacaga taaaactcaa gaagtcatca atcaatccca gtcattaaat
    14581 gaattatctg ataaggcgaa agaagaagca gttgccatta tttcttcagg gattagtgac
    14641 tatattgata tgagtggtga aatcaattat ggcgataaag acaaaattgt acgcatgata
    14701 aaagctttta tcaaaacttt tgatgtgaag gcagatctta agtttaatga tacttaccta
    14761 gtaggaaaat taattaatat ccttgggaca gagaaagata cggaaacgtt tatttcctct
    14821 ttgtctatgt tgtttacaga taagcatttt tcaactcagc ttggtggaga ggaactagtg
    14881 gaaatctttt aaccattacg cccagcatta ataaaagtat atcaaaaaag tactcctgat
    14941 gatttttaag attggtttga gaaataatgt gaaaacacta tttttaatgt taattataga
    15001 tagagatgaa cgcgtcatat ggttaaaaga atgaaaaagt caaagataca ctgctatatt
    15061 tcactaagga tatagcagtg tatctttcat gtcgtttcac tggcagtttt ttataaaagg
    15121 aggtgtgcat ttcagttgct tttctttggt agttagttga atcgtttaag aattaacgga
    15181 tgtggcagac aggtgctctg tccaaaaacc agtaaaatct ttgatggttc catctttatt
    15241 tagctgtgcc tgttcaaata ctgttttgtt tttaccgaat ggatcaattg caataattgt
    15301 tccgatcccc gcacgtttgg cagcaagtaa tcctgagtaa gcatcttcga taacaagaca
    15361 atcagccgga gctaagctca gtttgtctgc cgctttaaga aaaatatccg gttgcggttt
    15421 cccagggaaa gagccgtcgt catagacaat cttgtcccag tcaaaccagc gggctaaatc
    15481 gaaaatatca aaataaaaag caacattctc tttgacagta gccgtggcaa tcgttaatgg
    15541 aatctgttgg tcagtcagct ggtcaagagt cgcttcaagc ccttttgtca actgaagctc
    15601 gttttcattt tgcaagcaaa gcatacgata atagctttct ttttcttctg acaatacggc
    15661 gatctcagag gcggtcaaat gctctgaaat gaaatgtttc aaaatctccg tattcgtccg
    15721 accatgaata ttttttaaaa tatcctcgtc tgataaacca tcttttgtat gatcatgtat
    15781 catatgcagc caagcagctt catgcagatg agagtccaaa aacattgttc cgttgaaatc
    15841 aaatataatc cctttcatag ttacgctcct atagtggtat tttcggttga atcagcaatt
    15901 tgcagatcga catattgtgc atagtgctct tgaacctccc gcgagatctg gcgatccgta
    15961 atgagcagat cgaaatcatg caaattataa aacacataaa aatcatctcg attgaatttt
    16021 ttattatcaa cgagtagata tttcttacgg gaattattta gagcgatctg ctgtgcttct
    16081 ccttcttcgg tactgtaagt agagatcgct tcgttgtgaa cgccatttga actgataaat
    16141 gcttttgtaa actttagtct tcttaaattg tcgttggtga tcggtccgac aaatgcgccg
    16201 gtatttttcc ggaaatcacc gccaatcagt agaatttctg gtccatctgc ttgagcaaga
    16261 atatcaaaaa ctggataatt atttgtaatg atccgaattt tcttgttcag taaatgcgtc
    16321 gccaatagtt cgattgttgt acctggtcct aagaaaatcg tttctccctc gtgaatcaag
    16381 gaggctgctg tggcagcaat ttcttttttt tcttgaatct gcagagtggc tttttcagtg
    16441 tgagaaagtt cttgatctaa agtgtaggaa agactttgag cccctccatg gacacgcagc
    16501 agcttgcccg atttttctaa ttcatctaaa tctctgcgaa cggtcatatc agaaacatct
    16561 aattgattga tgatttcatt aacggtaagg attccttttt tattgaccat ttctacgata
    16621 gtaagcaatc tttctttttt caacattgtc ttcacctcta atttaaggat aatctatcat
    16681 ataaacggac aacagtcaat ctaattcgaa caaaagtaaa catttagggt ggtttttatg
    16741 tttgttacaa tagattttat tgctgttttc tggtttttat gattatttgt gtttgttttt
    16801 gttgacaaat gttttggatg cgtttacaat gcaatcagtt agaaagagcg aaaactgatt
    16861 atagatttga ggagagatgt acatgcttaa attaccagaa gattttattt ttggcggagc
    16921 cacagcagcc tatcaggttg aaggagccac taaggaaggt ggcaaaggcg ctgttgcttg
    16981 ggatgacttt ttagaggaac aagggcgatt cagtcccgat ccggcaagtg atttttatca
    17041 tcaatatgca aaggacattg aattgtgtga acgttttggt gtaaatggtc taagattatc
    17101 cattgcttgg agccgcattt ttcctgatgg agctgggaaa ccaaatccag aaggaatcgc
    17161 tttttatcat cgtgtgttcg aagaatgtaa gaaaagaaac gtaacgccgt ttgtgacgtt
    17221 gcatcatttt gataccccta aacgtttgtt tgaccatgga gattttttga atcgagaaac
    17281 aatagaagca tttgtttcct atgccatttt ttgttttcat gaattcaaag aagtcaaggt
    17341 gtggagtacc tttaatgaaa tctatccagt tgcaaccaat caatatttgt taggtgtttt
    17401 cccaccagga atcaaatatg attttacaaa gatcgtcgcc tgtcttcata atatgatggt
    17461 tgctcatgcc cgtgtagtga actatttcaa agaaaacgaa cttccgggtg aaattggtgt
    17521 agttcactca ttagagacga aatatgcggc aacagacgcg ccggaagata agcatgctgc
    17581 ctttttagac gatgcattgt cgatccgttt cttattagat gctacctatt taggctatta
    17641 ttcaactgaa accttgactg ctcttgatga gatatgtgaa gcaaatcagg ccagctatca
    17701 ttttcctgaa gaagatttcg ttgaattgaa aaaagcatcc acgcgtaatg actacttagg
    17761 gatcaatcac taccaatgcc attttgtcaa agcttacgat ggagaaaatg caatccatca
    17821 taacggtacg ggtgaaaaag ggacctctgt ttataaagtg aagggaatcg gagaacgtat
    17881 ttataaagaa ggaattcctc gaactgattg ggactggctg atttatccag aaggtctata
    17941 tgacttgttg ctgcgaatta aaagcgatta cccacattac aacaaaatct atatcactga
    18001 gaacgggatg gggtataaag atcagtttga agatggcatt attatggatc agccgagaat
    18061 cgactatttg agagtctatt tggaatcctt aagcaaggcg ataacagccg gggtaaatgt
    18121 gaaggggtat tttttgtggt cgcttatgga tcttttctca tggacaaatg ggtataacaa
    18181 aaggtatggc ttgttttatg ttgattttga aacccagaag cgttacccaa aagaatcagc
    18241 ttactggtac aagttggtca gtgaaaccaa aacgattatt taataagtga taatggagga
    18301 agaaaagatg aataaagagg aattacaaat gcttggtttt gagatcgttg catattcagg
    18361 cgacgctcgc agtacattat tgaaattatt gaaagaagta agacaaggaa actttgaaca
    18421 tgttgattcg gcgttgaaag aagccgacga aaatttaacc cttgcacata attcgcaaac
    18481 aaaaatttta gcggaagaag catctgggaa agagatggag atgggattca tttttatcca
    18541 tgggcaggat catttaatga ccactttatt gctgagagat ctgattcaag actttattgt
    18601 actgtacaga cagaatcaag gataggagaa gaacgctatg gatggaatca ttaaacaaat
    18661 cgaaaaaggg aaaccatttt ttgaaaaaat ctcacgtaat agttatttag gagccgttcg
    18721 tgacggattt ttaacagcga tgccagctat tttattttca agcattttca ttttgattgc
    18781 tgcggttcct gagatttttg gttaccaatg gcctgaatct gtctccacat ggctatggaa
    18841 agtctataat tattcgatgg gtgttgtagg gttactcgtt tcagcaacca ctgctcgctg
    18901 cttggctgat tcgatgaatc gtcgcttacc gaaaaacaaa gtaatcaaca ccacctctgt
    18961 gatgctggcc tctgtggtaa gtttcctgtt gttaagcgtc tctccgattg aaggtggatt
    19021 ttcaacggaa tatatgggga caaagggact actggcttcc tttgtcgctg catttttaac
    19081 agttaattta tataagtttt gtgtgctgaa agatattacc attaaaatgc ctaaagaagt
    19141 tcctggaacg atttcgcaaa ccttccgaga tatttttcct ttctcttttt cagtatttgc
    19201 ggccgtttta attgatttag gcattcgaca aatcttccaa atctcatttg cagaagcaat
    19261 cattacggtg ctgcagccgc tatttacagc agctgacggg tacttaggaa tcgctattat
    19321 ctggggagcg atggcgctgt tttggtttgt cggtgttcat ggaccgtcga tcgtggagcc
    19381 ggcaattgcg gcaattatct atgccaatgt ggaaaccaat ctgcaattgt tcaattccgg
    19441 tgaacaagct tctaaagtac tgacggtggg tttagggaat tttgtaggaa ctatgggagg
    19501 aactggggca acattggttg ttccttttat cttcctactc tttgctaagt ctaagcagtt
    19561 gaaggcagtt gggaaagctt cctttattcc agtaagtttc gctgtcaacg aaccattgct
    19621 atttgcggca cccatgattt tgaaccctta tttttttatt ccatttttgt taacacctgt
    19681 tgtaaacgtt tgcctgttca agttttttgt cgatgtattg ggcatgaaca gctttatgta
    19741 cgttttgcct tgggcaactc cagcaccgat cggtttggtt ctaggaacgg gcatgggtat
    19801 cttagctttt gttctagcag cggttctaat cgtcgttgac ttcctgatct atctaccatt
    19861 ttgcaaagca tacgatgctg tcttagtaga gaaagaagca caaaaagcag aggtgatcgc
    19921 aaccgaggaa ggtgcttctg ccgatgtacg tgaggaagta cctgtggcag cgagtcaagt
    19981 tatcagcgat gcaaataaag aaatcaatgt gttggtactt tgtgctggcg cagggacaag
    20041 tgcgatgtta gctaatgctt taaaaaaagg tgcatctgaa tcgaaagcac cgatcagtgc
    20101 aatggcgggt gcttatggtt ctcattacga aatgctgcag gattttgata tggtggtctt
    20161 agcaccgcaa gtcaattctt actatgatga tatcaaagaa gacaccgatc gcttaggaat
    20221 caagctggtt gcgacaaaag gagcagaata tatcggatta acgagagatc ctgaaaaagc
    20281 tgttcagttt attctgaacc aatttcaata aaggaggagc cataatgaaa atgggaattt
    20341 ggttgcgtaa agctgtttta tttgcagctg tgttaggggc tttgggggct gtttcaaaaa
    20401 ctgttgaagc atctgccagc gaatttattc gcggagcaga tatttcgatc ctgtcagata
    20461 tggaaaaatc tggtgcaaaa tattatgaag acgatatttc aaaagatgcc ttagagattt
    20521 taaaaaataa tggtgtcaac tatgttcgac tgcgtttgtg gcaggatcct tataatagta
    20581 atggagaaag ttatggagca gggacaaatg atctggaaac gacgattgac cttgcaaaac
    20641 gagcaaaaaa tctgggactt aaggtgctgc tggattttca ctacagtgat ttttgggttg
    20701 atcctgggaa acagaatctt cctaaagcat ggcaaggtct gacctttgaa gaaatgaata
    20761 cggcattgta cgactataca aagaacgttc tgtcggaaat gaagcagctg gacgtttatc
    20821 ctgatatggt tcagatcggc aatgaactga atagcggaat gctctggcct tatggcaagt
    20881 cttggggaga aggcggggga gaatttgatc gattggctgc ttttttgaag tctggtatcc
    20941 aagctgttcg agacactcaa cctaaaacaa ctccagtaat gctccactta gctgatggtg
    21001 gcgatacagg agcatttact tggtggtttg atgaaatcac gagtcgaggt gtgtcatttg
    21061 atttaattgg agtgtcgtat tatccgtatt ggcacggttc aatgaatgaa cttcaaacca
    21121 atatgaatgc gatcagccaa cggtatggta aagaagtgat cgtagttgaa acagcttatg
    21181 ggcatacaac agcgaatgcc gatactatgc caaatgcttt tggtgaagcc gaagcagctg
    21241 cggggggata tgaaccaaca ccgacaggac aagcagagta tttgctggat cttgccgatc
    21301 ggattcaggc agtaccgaat aatcgcgggg cgggcttctt ctattgggaa cctctttggt
    21361 acaacggaaa tgtgagttgg gcaacacaag caggtatgaa ttatctcagt gttcaatcca
    21421 ctatgggaaa cgaatgggac aaccaagcga tgtttgattt tgctggaaac gccttgccaa
    21481 gcttgcgtgc gtttaaacaa gcaggggcgc aaataaatct agttaaaaat gcaagtttcg
    21541 aaagcgatgg accaacgacc agtccttcca attggcaaac ctggtttcaa caaggaaccg
    21601 ctaagggtac gatcaaaacg gaagcgggca ctttttttgg ggactacaaa ctaacttttt
    21661 ggcaggatca agcatacgag gcatcagctt atcaaaatgt tagtggcata agcaaaggaa
    21721 cttacacatt gagtgcctat gtaatgtctg ggggagagtt tgatactaat cagttatata
    21781 tcaaaaatta tggtggagcg gaactaaata ctgcggttgt taaaacaagt gaatggacaa
    21841 aaattacaat caaagacatt ccaattacaa caggtgtttg tgaaattggg gtttatagca
    21901 aggcttcagg aaatgcttgg acgaacgttg attttgtttc attggtgaaa caatagactg
    21961 cggatcgttt cgattcaaga tcggaggttc ccttcagcca catcgttagc gtagaaggca
    22021 ggaatcgaac ctgcacctcg cctttgccaa aaataaccag aaacgatttc cagtcatttt
    22081 taccaaaacg agtaaagcac cagacttcat ctacactttg tattatgcta aagagagttc
    22141 aacgatttcg taagaagcaa tgaaaaaatt gcaaaaagtt gtgcagataa cataaagttt
    22201 gtttaagaaa gggtaacctt agaattccgt cgtgaatatg atttgagcac ttagatggat
    22261 agaaaaaagt tctcggaaaa cagttcgttt ttcgagaact tctttttatg ataagaatga
    22321 aacaaattaa cttatattat agtctctttt ggtagggaac catcttattt ttaatgaaaa
    22381 tcaagcattt tagctattga agaatgttga tttataggga ttccccctcc atattatgtt
    22441 ggctctttat tcccactcca ctgttgctgg tggtttagaa gtgatgtcat acacgatacg
    22501 gttgacgtgg gctacttcgt ttacgatacg tacagagatt ttttgcaaga cttcccatgg
    22561 gatacgggca aagtcagcgg tcattccgtc gattgaagtt acagcacgga taccgactgt
    22621 gtagtcgtaa gtacgtccgt cacccataac accgacagag cggatccctg gaagaacagt
    22681 gaaatattgc cagatatcac ggtcaagtcc agcagctgcg atttcttcac gcaagatagc
    22741 atcagattcg cgtacgattt ctagcttgtc ttcagtgatt tcgccaagaa cacgaatacc
    22801 aagaccagga ccagggaatg gctgacgcca aacgattgaa tcaggcatgc ctaactgagt
    22861 ccctaattca cggacttcgt ctttgaataa tgtgtttaat ggttcgatca attcaaattg
    22921 catatcttct ggcagtccac ctacattatg gtgagatttg atcgtctgtg ctgtttctgt
    22981 accagattcg ataacgtcag tatacaacgt tccttgtgct aggaaagaga cgccttcttc
    23041 accagcaagt tttgttgctt cgtcatcaaa aacatatacg aattcattcc caatgatttt
    23101 acgtttttgt tctgggtcag atacaccttt caacttgtct aagaagcgat ctcttgcatt
    23161 gactttgatg atgttcaagc cgaattttcc gcctagactt tccattactt gttccgcttc
    23221 gcctttgcgt agcagaccgt ggtcaacaaa gatagatgtc aattggtcac cgatcgcttt
    23281 ttgtaaaaga accccaacga cactagaatc aacgccacct gaaagaccaa gcaagacttt
    23341 tttgtcacca acttgttcac ggattttttc tacttgcata tcgataaagt tatccattgt
    23401 ccagttacct tcacagtgac aaacatcaaa ggcaaagtgg cgcagcaatt cgattccgta
    23461 ttcggaatga cgtacttctg catggaattg gataccataa aaattacgtg ttgtgtcttg
    23521 gatagaagca atcggacaat ctttgcttgt tccgactgtt tcaaagcctt caggaacttt
    23581 agttaccaag tcaccatggc tcatccatac tgtttgttgt tttggtgttt ctttaaacaa
    23641 gacagcttga tcgcttgtta cttctaacaa ggctttccca tattcgcggt ttttagcagg
    23701 ctctacggaa ccgccaagtt tgtacgtgat caattgcata ccatagcaaa tccctaatac
    23761 aggaatacct aaattgaaga tctcaggatc gatcccaaat gcattctcat catatacact
    23821 gtttggtccg ccagaaagaa tgattccctt tggattcatc gcttttactt cttctgcagt
    23881 aatgcggtgg ctcaataatt cggaaaagac tccaagatca cgaatacgtc ttgtgatcaa
    23941 ttggttatac tgactaccgt agtctaatac gataatcttt tcaacgttcg tcatatcggc
    24001 aacgtttgtc aaatttatta cccctatccc tttaaatttt atctcaaaat agtcaaacta
    24061 ttttaaaatg ctaatatttt cgcatgaaaa tcgaatcgat gatatgattt tcagttttat
    24121 ggagaattat atcggctctt cctcgtgtag gcaagatata ttcctgtaaa tttttcaaat
    24181 tcacattttt ccatacatct tttgccattt taaaggcttc ttcacgatct ccgatagcaa
    24241 aacgataata ataattctct ggattttgga aagccgtatc cagtaacgca ccaaaacgat
    24301 ccaaatacca tttttcgatc agcacgggat cggcatcgac atagacagaa aaatcaaaaa
    24361 agtcgctgac gtagatttgc tgattcgcag gtaattgaag cgtattgatc ccctcaacga
    24421 tcaagatatc aggctgctgg atcaattcgt acttgtctgg aatgatatca tacacatcat
    24481 gtgagtaaac aggtactttt atctcttcct gaccagattt tacacggttc aagaaatcga
    24541 tcagcatctc catatcataa ctttcaggaa atcctttacg gtccatgatt ccacgctctt
    24601 ttaatatacg atttggataa agaaatccgt cagtcgtgat cagctgaacg tttcttcgtt
    24661 tgaaggtacg agacaaaatc gtctgcagca gtctggctgt tgtacttttt ccaacggcta
    24721 cacttccggc gatcccgata ataaaaggcg gtacttctac gtatttatga agaaataaac
    24781 ctttactcaa gaacaaagat tcaaattctt tcatataaag ataaatcaga tgagcaagag
    24841 gtacatagat atctcgaaca tcctgcatgg aaatgcggtc attcaaactt ttgatattat
    24901 ctagttcatc ttgtgtcaaa ggtgcttgcc cattacgata aaattctcgc cattcttctc
    24961 ttgccacacg gtagtagttc attggatcat tcatattagc ctcctgcgtt ctcccatcaa
    25021 tggaactatt ttaacacaaa ataaacgcaa accccaccac ttaagagaga ttgccgatct
    25081 ttttgtataa tctttataat agaaagaaac ggagtcttat tcttgacttg cgcacggata
    25141 cataaaagga tagactgttg tcatgaaaga aatgagaagg atggaagaca tgacaaatca
    25201 ttactattct gaacgcccag atacggcgca cgattttgaa caatgggctt ttgagttaaa
    25261 aggcagaacc tttcaatttg taacagattc tggtgtattt tcacgtgaaa cagtggatta
    25321 tggttcacgt gtcctgattg atgctttcga ttgggaagag ttacctgatg aaggaaagat
    25381 cttagatgtg ggatgcgggt atggaccgat tgggttagct ttggcatttg cgacacagcg
    25441 gtttgttgaa atggtcgaca ttaatgaacg agcggtaagt ctagcgcaag gaaacgcaaa
    25501 gcgtaaccaa atcgaacatg ttgatatcca tcaatcgaat atctatgaag cagttcatga
    25561 agaaacctat gcagctatcg taagcaatcc gccgatccgt gctggaaaaa aagttgtaca
    25621 tgaaattttg acaggcgcat atcctcggtt gaagaagggc ggtacactga caattgtgat
    25681 ccagaagaaa caaggagcgc cgagtgcgca aaagaaaatg gaagaaacat ttggtaatgc
    25741 agaaatcgtc acaaaagata aaggatatta tatcatcaaa agtgtgaaag aataactagc
    25801 tgaaaaatag tggagcgacg aaagagtgga actgggcgtg catgtacggg tacgtatcag
    25861 ttcttttttt gttgagaagt ttttaaaaac aaagaactat tttttcttca aaaagaaata
    25921 gtaggaacag agtcgttgtt ttttacgata aaataaataa gatacagaac ttgtatagaa
    25981 gactgccaag tcggtagata aaggaggttt ttatcaaaaa acatactttc cttttttctc
    26041 tattcttttc ttgggggttt tggtacactg atagggaatt tagatagaag ggagccaata
    26101 ggatgaagct gaccatcaga gatatcgcag aaatggcagg cgtatcagta acaactgtct
    26161 cacagatttt gaataacaaa ggaagcagat ttagtgataa gacaagaaaa aaagtgttgt
    26221 cgatcgtgaa tgaacatcat tataagcccg attatttcgc ttcaaatgtg atcaatcgac
    26281 attcaaagac catcggaatg atcgtccctg atgtcactga tttcttcttc tccaaactga
    26341 tcgaaggtgt agagagctat ttgaatcctt tgggctatgt gatcatgtta tgcaattctc
    26401 gtcatagcca agaaaatgag atcaagtatt tacaagagct ttcccaccgc tcagtggacg
    26461 gaatcttgct ggccacacca aatattttac ctgagaaata tgcattagac agcggttttt
    26521 atcaaaaaat gccaatcatt ttaatcgatc gcggattgaa tcgtcgggat aacggacggc
    26581 ttatcgtaaa ggaatatgag ggcgcctatc aagctgtttc gctgtttatt gaaaatggcc
    26641 atacgaagat cggcatgctg aaggaaacca ctggatacta tcaattagaa gaacgtttca
    26701 acggatatcg tcatgcgctg aaagatcatg gcctgccttt taatgggaaa tttgttgaac
    26761 atggagagtt gactgtccaa ggtggatata ctgcatcaaa aaaattactc aaacataaag
    26821 atatcacggc tattttttgc gggaatgatg ccatggcgat cggatgctat caggcgatcg
    26881 atgaattggg caaaaaaatc ccagaagata tctcagtcat aggattcgat ggattaaagc
    26941 tgtcagaata catgattccg caattgacga cagtgcagca gccaagtttt gatattggat
    27001 tttatgctgc acgtttcctg atcgatacga tcgaatttcc tcaaagaaaa gttccgaaca
    27061 aagtgttcga aacaaaatta attattcgtg agagcgtaaa agtattgaca aagggctaac
    27121 tcggcggtat attgcttatg taagcattta caaaggctag ttagtgcttt ttttattttt
    27181 agtaaaccag tttactaaag tggtttacct ttcctaaaaa taatgtataa taccgaatga
    27241 agacaaggag gatcaggcaa tgcgaatggt ggatctgatt gaaaaaaaga gggatggaaa
    27301 cgagctgtcg aaagaggaaa tcgagtacat cgtcacgaac tatacgaatg gaaagattcc
    27361 agattatcaa gtcagtgcat tattgatggc aattttttat caagacatga caaatgaaga
    27421 aatcacgaac ttaacattgg cgattgctaa ttctggtgat gtcatcgatt tgagttctct
    27481 tgaaggaata aaggtagata agcattcgac aggtggcgtt ggtgacacga ccacattgat
    27541 tttagccccc ctagtagcta gtgtcggagt gacagtggct aaaatgtctg gacgcggtct
    27601 aggttacaca ggtggtacac tagacaagct agaagcaatt cccggatttc agatcgagct
    27661 ttcggatgaa gaatttgtac gcattgttaa tgaaagtaaa gtagcggtaa ttggtcaatc
    27721 aggaaacttg gcaccggcgg acaaaaaatt gtatgccttg cgtgacgtca cagcgaccgt
    27781 tgattctctt ccgctgattg ccagttcgat tatgagtaaa aaaatcgcgg caggagcaga
    27841 tgcaatcgtt ttggatgtga ccactggaga cggtgctttc atgaagaaca tcgaagatgc
    27901 aagacgtctg gcaaagacca tgacgagcat tgggaaactg gctaaccgag aaacagtggc
    27961 ggttatctca gatatgtcag aacctcttgg cgaagctatc ggaaatagtc tagaagttgt
    28021 cgaggcaatc gaaacattac aaggaaatgg tccagaagat ctagtagaaa tgtgctacgc
    28081 cttaggaagc caaatggttg ttcttgctgg caaagctaag acaaccgatg aagcaagaac
    28141 gttgcttcaa gaagctctgg aatcaggtaa agcgttagca aaattcaaag aaatgatcca
    28201 aaatcaaggg ggagacccag cgatcgtgga acatccagaa cgaattttga ctgcacgcta
    28261 cacaatggag cttcctgcta aacaaagcgg agttgtgtca aaaatcgtgg caaatgaatt
    28321 aggaattgct gcaatgatgc taggtgctgg gcgtaaaacc aaagaagaag atattgatca
    28381 cgctgttgga ttgaaactgc ataaaaaaat tggtgacact gtgacaaaag gtgagtcact
    28441 attgacgatc tatagtaacg acgaagaaat cacttctgtc attgaattat tatataaaaa
    28501 tattgaaatt ggtgaatcgg caatgaagcc aacgttgatt catgacatca tcacagaata
    28561 aaggaaaaaa gcggacttta ccgttttaaa gaaaagggga aaagaaatgg aactaaaccg
    28621 aatgatcgac catactattt tgaaagcaga cgcatctaaa gaagctgtga tgcaaattat
    28681 cgaagaagca aaaaaatacc atttttattc tgtctgcatc aatccagcat gggttgcgct
    28741 agcgaaagaa caattacaag gtgagccagt agccgtatgt acagtaatcg ggtttcctct
    28801 aggagcaaac acacccgaga caaaagcatt tgaaacaaca gatgccatca ataacggtgc
    28861 agatgaagtc gatatggtca tcaatatcgg tgctttgaaa tcaaaggatg atcaacaagt
    28921 ccaaaaagat atcgaagcag ttgttgaagc agcaaaagat cgtgcgcttg tcaaagttat
    28981 tattgaaaca tcgttattag atagagaaga aatcatccga gcttgcgaaa tagcaaaagc
    29041 tgcaggcgct gattttgtca aaacatcaac tggtttctca acaggcggag caaaggtaga
    29101 ggatgtccgt ttgatgcgtg aaactgtagg accagaaatg ggtgtcaaag cttccggcgg
    29161 tatccataac gaagaagaag caatggcaat gatcgaagct ggtgctacaa gaatcggaac
    29221 aagcgcagga gtagcaatcg tatctggttc aactggtgaa ggctattaat tttttcaaag
    29281 gagaagctca tggcagaact caaacaagaa tggatcaaca cagctattga agcgttagat
    29341 aaagcctatg ttccttattc ccattttccg gtaggcgctt gtctcgtaac ggaatcaggc
    29401 aagatttatc aaggcatcaa cattgagaat gcatcatttg gattaacgaa ttgtgccgag
    29461 cgcacagctt ttttcaaagc agtatctgaa ggagaaaaaa catttacgca tctagtcgta
    29521 gcggggcaca cccccgatcc tatctctcct tgtggtgcat gtcgacaagt aatggcagaa
    29581 ttctgttccc ctgatatgcc ggttacgcta gtaggagaca atggtgtgac gaaggcaacg
    29641 accgttcgtg cactgctgcc ttatgcattt actgaaaaag atctataact catgttcatt
    29701 cagtcagctg actgttgaaa aataaaacaa ttattttagg aggctttaca gaaatgaaaa
    29761 aagcaaaatt atttggttta ggtgctgtcg cactagcagc agggttattt ttaggtgcat
    29821 gcggcaacaa cggctctact gattcatccg gtggcaaaag ctcatcagac acaacaactg
    29881 cagcattgat cacagacaca ggtggtgtag acgaccgttc attcaaccag tcagcttggg
    29941 aaggactaga aaaatggggg aaagatcaag gactttcacg aggaaatgat ggcttccaat
    30001 atttccaatc ttcaaatgaa tcagattaca tcccaaatat tgaccaagca ttgaatgctg
    30061 gattcaaaac gatttttggt attggttata aactaaaacc agcgatccaa gaacaagcaa
    30121 caaacaatac aggtacgaac tttgttatta tcgatgatgt catcgatgga ttagataacg
    30181 ttgtatctgc aactttcaaa gacaacgaag cttcttatct tgcaggtgtt gcagcagctt
    30241 atacgactga aacaaacgta gtcggcttta tcggcggtgt aaaaggtgaa gtaatcgatc
    30301 gttttgatgc tggattcaaa gccggtgttg atgcaggtgc gaaagaatta ggaaaagaaa
    30361 tcaaagtatt gaatcaatat gctggtgact tctctgctcc agataaagga cgttcaattg
    30421 ctcaaggtat gtatgcacaa aacgcagata tcatcttcca tgcttcaggc ggtacaggta
    30481 acggtgtatt ccaagaagca aaatcattga acgaatcagg cgacaaaaaa gtttgggtta
    30541 tcggtgttga ccgcgaccaa tcagacgaag gcgaatacac attaaacggc gaaaagaaaa
    30601 acttcacatt gacatctaca ctgaaagcag ttggaacagt agtagaagat ttggcacaaa
    30661 aatcagcgga cggtaaattc cctggcggcg aacacactgt ttatggattg aaagaagacg
    30721 gtgttggtct aacagaagga caactttctg acgaagcgaa aaaagcagtt gatgaagcaa
    30781 aagaaaaaat catttcaggt gacgtaaaag ttccagaaac tcctgaagaa aactaaaacc
    30841 atttctatag ccttgttaga cacatgtttg acaaggctat ggtttgatta gaacaagaat
    30901 tgttcattta tccaagctgc cttgtgacag tttggataag ggaacaactc cctgaagtaa
    30961 tgtttgtttc aaaagaagaa cgctcactaa gcgtgaatct tagtcaatcg ttgccctaga
    31021 tagaaatcgt taggatgtga aaaaaaggtg gttcaagaaa atattgtcat agaaatgcag
    31081 aatattacca aagaatttgg aacattcaag gcaaatgaca acatcaattt acaagtaaag
    31141 gcaggagaaa ttcatgcgtt gcttggagaa aacggtgctg gcaaatctac attgatgaac
    31201 gtgctttccg gattattaga gccgacatca gggaaaattt tgatgcgtgg gaaagaagta
    31261 aagatcacaa gtccgaccaa agccaaccaa ttagggattg ggatggtcca tcagcacttt
    31321 atgcttgttg atgcctttac tgtaacagaa aacatcgtgt tgggaagcga gcctagtcgc
    31381 gcagggatgc ttgaccataa aaaagcacga aaagagatcc aaaaagtttc tgaacagtat
    31441 ggattgtcag tcaacccaga tgcttacgtt cgtgatattt cagttggaat ggaacaacgg
    31501 gtagaaattt taaaaacact ttaccgagga gcagatgtac tgatttttga tgagccgaca
    31561 gctgtattga cccctcaaga aattgatgaa ttaatcgtga tcatgaagga attagtcaaa
    31621 gaaggcaagt cgatcatttt gattacgcat aagttagatg aaatcaaagc agtagctgac
    31681 cgctgtacag ttatccgccg tggaaaagga atcggtacag tcaacgttaa agacgtaacc
    31741 tcacaacaat tagccgatat gatggttgga agaacggttt cattcaaaac gatgaaaaaa
    31801 gaagcgaagc ctcaagaagt cgttttgtct attgaaaatc tagtggtgaa agaaaatcgt
    31861 ggattagaag ccgtgaaaaa cttgaactta gaggttcgtg ctggcgaagt acttggtatc
    31921 gctggaatcg atggaaacgg gcagtcggag ttgatccaag ctttgactgg tttgcgaaag
    31981 gcagaaagcg gacatatcaa gctaaaaggg gaagacatca ctaataaaaa accccgaaaa
    32041 atcactgaac atggtgtagg acacgtgcca gaagaccgtc ataaatacgg gttagtccta
    32101 gatatgacat tatctgaaaa tatcgcacta caaacctatc atcaaaaacc ttacagtaaa
    32161 aacggcatgc tgaattattc agtaatgaat gaacatgcca gagaattgat cgaagaatat
    32221 gatgttcgaa caacgaatga acttgttccc gcaaaagctt tatcaggcgg aaatcagcaa
    32281 aaagcaatta tcgctcgtga agtcgaccga gatcctgatc tgttgattgt tgcaaatcca
    32341 actcgtggac tggatgtagg tgcgatcgaa tttattcata aacgtctgat cgaacaaagg
    32401 gacaaataca aagcagtgtt actgatcagt ttcgaattag aagaaatttt aaatgtttcg
    32461 gatcgtattg ctgttatcca tgaaggagaa attgtcggta tcgttgatcc gaaagaaaca
    32521 tctgaaaatg aattaggtct attgatggcg ggctatacct tagaagaagc acgaaaagag
    32581 ttagaaaagg gggctggcgc acatgaatga tcgcagcgaa aaattccgta atttattagt
    32641 gcctgtactt tcagttgttt taggattgat cttaggcgcg atattgatgg ctgcttttgg
    32701 ttttcagccc atccaaggtt attcttctat gctagatgca gcccttggtt cgcaaagagg
    32761 gataggtgaa acgttaaggc aagcaacgcc gttgattttt acagcattag gtttttctgt
    32821 agctaactca gctgggtttt tcaatattgg gctttctgga caagcacttt gcgggtggat
    32881 cgtcagtgtc tgggtggcac ttgcgtttcc agatctgcca aaagttgttt tgcttccgtt
    32941 atgcgtgatc ttaggtgcct tagctggtgc gatggcagcg gctgttccag gtttacttcg
    33001 agcatttttt ggaacaagtg aagtgatcgt aacaatcatg atgaactata tcttattata
    33061 cgtaagcaca tttgctttac atgaagtgat gcctgaaagc tatcgctcaa gtttggactc
    33121 ttccaatatg atcagtcaaa atgcctcact gcggttacca tggttaacac aagcttttgg
    33181 cggctctcgc gtaaactcag gattattttt agcaatcatc gcgcttattt tcgtttggct
    33241 gctgatgaag aaaacgactt taggatttga aatccgttct gttggattga atccttttgc
    33301 ttctgagtat gcaggaatga gtagtaaacg tacgatcgtt ttgtcgatgg tcatttctgg
    33361 cgctttggca gggcttggcg gtgtggttga aggattagga acgtatcaaa acttctttgt
    33421 tcaaacgact tcgctatcta ttggatttga cggaatggct gtttccttgc ttggttctgg
    33481 atcagcaatc ggtattcttt tatcagcgat cttgttcagt attttgaaga tcggtggact
    33541 tggcatgcag acaggagcag gtgttccgtt tgagatcgtc aatgtatcga ttgctttgat
    33601 tatcttcttt gtcgggatca acttcctgat tcgtttcgtc atggctaaag tcttccaagg
    33661 gaaaaaacaa gaagagatcg ttgcgacaat agaatcgaaa ccaacgaatc aaaaccatga
    33721 agggggcgaa ctataatgtc gactatcgaa ttaattgcct tgatccttac ttctacactg
    33781 gtttattcaa caccgctaat tctaacgtca ctaggcggaa ctttttctga acgaagcggg
    33841 atcgtaaacg tagggctaga gggaatcatg gtcatgggtg cttttagttc catcgttttc
    33901 aacttgacga tgagtccatc acttggttct atgacaccat ggatcgctat tttagtgggt
    33961 ggcgtcgtag gtatcctatt ttctctgatt cacgcagtag caacagtcag tttgcgtgct
    34021 gaccatatta tcagcgggac agtaattaat ctgatggcac ctgctttagg tgttttcttg
    34081 atcaaagcat ggtatggtaa aggtcaaact gataacatca cgcagaatct ggggtatttt
    34141 tctttcccag gattagcaga tattccggtc attggaccaa ttttctttaa aaatacattc
    34201 ttacctgctt attgtgctat tttgattgct gtcctagctt gggtgatcat cttcaagacg
    34261 aaattcggct tgcgcctccg ttcagttggt gaaaatcctc aagctgccga cacattaggt
    34321 atcaatgtat atgctatgcg ttattcaggc gtactgattt ctggcttgtt aggcggtatg
    34381 ggcggtgctg tttttgctca gtcgatttcc ggtaactttt cagctggtac gatcgttgga
    34441 caagggttca tctccatggc tgctatgatc tttggtaagt ggaatccttt aggggcaatg
    34501 ggtgcctcat tgttctttgg ttttgctcaa agcttgagta tcattggcgc acaattacca
    34561 gttatttctt cgattccgcc agtattgctg caaattgctc catatttgct gacaatcatt
    34621 gtgctggttg ttttcttagg gaaagcttct ggtccaaaag caaacgggaa gaactatatc
    34681 aaatcaaaat aatcttttag cgaataaaaa gggtgggtta cgggaagtgt ttttcgtctc
    34741 gccctttttg ttttaaaggc aataaaaata aaaagaaaga aggaataatc atgtttaaac
    34801 gcgtacatct gatcgtcatg gattcagtag gaattggaga agcaccagat gccgataagt
    34861 tcggtgatgt tggttctgat acattaggac acattgcgaa agaagcagga ttgaacgttc
    34921 cacatttaga gcagcttggt ttaggaacga tccgtcctct tgaaggtgtg gaatcagtga
    34981 aagatcatca aggctatgcg acgaaattag aagaagtttc tgtagggaaa gatacgatga
    35041 caggccactg ggaaatcatg ggattgaata tcaaaactcc atttcgtgtg tttcctaatg
    35101 gattccctga tgatctgatc aaacaaatcg aagaattttc tggccgtaaa gtcgtatgta
    35161 acaaacctta tagcggaaca gctgttattg acgattacgg tgaacaccaa atgaaaacag
    35221 gcgatttaat tgtatatact tctgccgatc ctgtccttca gatcgcggca catgaagaaa
    35281 tcattccttt agaagaatta tatcggattt gccaattcgt tcgtgatata acaaaagatg
    35341 atccgtatat gattggccga atcattgcac gtccgtacgt gggtgaacca ggagacttca
    35401 cacgaacaag caatcgccat gattatgcgt tgaatccatt cggacacaca gtccttgatt
    35461 ctttgaaaga agcaggaaag gacgtgattg ctgttggaaa gatcaacgat attttcaacg
    35521 gacaaggaat cactgaatct gtccgcacga aaagcaatat ggatggcgtt gaccagctgc
    35581 tgaaagttat gaaaaacgat ttttcaggaa tcagctttac caatttagta gattttgatg
    35641 cattatacgg tcatcgtcgg gatgtagtcg gctatgcgca tgcgattgaa gaatttgact
    35701 tacgaattcc agaattgctt gaagcgatgg aagaagacga cttgctaatg attacagccg
    35761 atcacggaaa cgatccgacg tttactggta ccgatcatac gcgagaatat gtaccgttat
    35821 tggtttacag taaaaaaatg aaagaacaag gggcattgcc tcaaggatat tattcagata
    35881 tttcagcaac gattgctgag aactttagtg tttcttcgac tgaaaatggc gaaagcttct
    35941 tgaaattatt aaaataatct ttttaaatag gagaaagcaa atgaccaagt taagcgagat
    36001 gttacaagaa acgacccagt ttatccttga taaaggagta aaagaaattg attttggttt
    36061 gattctaggt tcaggattag gtgaattagc agatgaaatc gaagatgctg taatgatttc
    36121 ttatgatgag atcccgttct ttcctgtttc gacagtagtt gggcatgcag gaaagctagt
    36181 ttatgggtct ctggcaggca agaaagtgtt agccatgcaa gggagattcc actactatga
    36241 aggtcattcc atgcaaacag tgacctatcc agtacgtgtg atggccggac taggggccca
    36301 ttcagtcatt gtgactaatg catgtggtgg tgtcaacgaa tcatttgtac caggagattt
    36361 gatgctgatt accgatcata tcaattttac tggtgaaaat cctttgatcg gtccgaatga
    36421 agatgcaatg ggccctagat ttccagatat gagtcaagct tatacgcctg actatcaagc
    36481 aacagcaaaa gcagcagcag aaaaactagg tttggatctt aaagaaggcg tatatatggg
    36541 ctattctgga ccaacttatg aaacgcctgc ggagatccga atgtctcgga caataggagc
    36601 cgatgcagta gggatgtcga ctgttccaga agtcatcgta gcagctcaca gcggattaaa
    36661 agtgttagga atctcttgta ttaccaactt agcagcaggt atgcaagcga atctgagcca
    36721 tgaagaagtt gtagaaacaa ctcagagagt caaacaatct tttaaagcat tggttaaaga
    36781 aacattgaca ttattgtaat aggaggaaca ataaaatgag tgtgcatatt gaagcgaaag
    36841 aaggcgagat cgccgataag attttacttc cgggagatcc tttgcgagct aaatatattg
    36901 cggagacttt tttggaagat ccagtttgtt acaatcaggt acgcggtatg ttaggcttta
    36961 ccggcaaata taaaggagaa cgtatttctg ttcaaggaac aggaatggga atgccatcag
    37021 ccaccatcta tgcccatgaa ttgatccagt cgtatggtgt aaagaaattg attcgagtag
    37081 gtacatgcgg tgcattgtca aaagacgtcc atgttcgtga tttagtacta gcacaaggtg
    37141 cagcgaccag ttcttcgatg atcgaaaaaa atttccaagc ctttcatttt cctccaatca
    37201 gtgatttcaa tctattactg aaagcatatg agatagctaa agaaaagggc tatacggttc
    37261 atgtaggaaa tgttctttcg gaagattctt tctacaaaga tgatttgaca gagacgttcc
    37321 aattagctga acttggcgtt ttaggagtgg aaatggaagc agcggctctt tattacttag
    37381 gcgcgaaata ccatgtgcag acattaagtt tgatgaccgt tagcgaccat ttgatcaccg
    37441 gtgaagaaac aacagctgca gaacgtcaat ctacgttcaa tgaaatgatc gaagtaggat
    37501 tggaaacagc gatagcagaa taagaaggaa atgaaaaagc tgccctgcat taagtaataa
    37561 gaacatccaa gcaaaaatag ctcctcatgt ttttgacttg gctggactta ttattgcaaa
    37621 tgtaagcttt tgaacaccgt ttaccaagag gttgtgaatc tgccgtttaa ctctgagtca
    37681 caaggaacaa tttcaaaaaa cagcttttca tgtttgatga atattgtga
//
LOCUS       DAZUJR010000017        37267 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.017, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000017 DAZUJR010000000
VERSION     DAZUJR010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37267
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.017"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..862
                     /locus_tag="ACG804_000819"
     CDS             <1..862
                     /locus_tag="ACG804_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFS4831768.1"
                     /translation="IDGLAPGAYQLVETQAPTGYELDATPIEFEIERSQTAVVELTKA
                     NRLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGVY
                     QLVETQAPTGYELDATPIEFEIERSQTAVVELTKENRLTPGGVVLTKIDDQSGEVLQG
                     AVFELQDANGTVLQSGLTTGADGKLAIDGLAPGAYQLVETQAPTGYELDATPVTFKIE
                     KEQEVAIFLTKENRKVADSSDIRGNNPTSSGNKHLPKTGETIISQFILSILGVLLVFI
                     SIKFRKKRNI"
     gene            complement(1215..2063)
                     /locus_tag="ACG804_000820"
                     /pseudo
     CDS             complement(1215..2063)
                     /locus_tag="ACG804_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2216..3328
                     /locus_tag="ACG804_000821"
     CDS             2216..3328
                     /locus_tag="ACG804_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFS4831769.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            complement(3406..3699)
                     /locus_tag="ACG804_000822"
     CDS             complement(3406..3699)
                     /locus_tag="ACG804_000822"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase family
                     protein"
                     /protein_id="HFS4831770.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            3867..4181
                     /locus_tag="ACG804_000823"
     CDS             3867..4181
                     /locus_tag="ACG804_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HFS4831771.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            4202..6181
                     /locus_tag="ACG804_000824"
     CDS             4202..6181
                     /locus_tag="ACG804_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFS4831772.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            6194..6520
                     /locus_tag="ACG804_000825"
     CDS             6194..6520
                     /locus_tag="ACG804_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HFS4831773.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            6536..7054
                     /locus_tag="ACG804_000826"
     CDS             6536..7054
                     /locus_tag="ACG804_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831774.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            7054..8406
                     /gene="celB"
                     /locus_tag="ACG804_000827"
     CDS             7054..8406
                     /gene="celB"
                     /locus_tag="ACG804_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFS4831775.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(8490..9995)
                     /locus_tag="ACG804_000828"
     CDS             complement(8490..9995)
                     /locus_tag="ACG804_000828"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HFS4831776.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(10087..10677)
                     /locus_tag="ACG804_000829"
     CDS             complement(10087..10677)
                     /locus_tag="ACG804_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFS4831777.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            10856..12502
                     /locus_tag="ACG804_000830"
     CDS             10856..12502
                     /locus_tag="ACG804_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis C-terminal
                     domain-containing protein"
                     /protein_id="HFS4831778.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            12551..13270
                     /locus_tag="ACG804_000831"
     CDS             12551..13270
                     /locus_tag="ACG804_000831"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFS4831779.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            13749..14696
                     /locus_tag="ACG804_000832"
     CDS             13749..14696
                     /locus_tag="ACG804_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4831780.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            14708..15628
                     /locus_tag="ACG804_000833"
     CDS             14708..15628
                     /locus_tag="ACG804_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4831781.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            15669..17126
                     /locus_tag="ACG804_000834"
     CDS             15669..17126
                     /locus_tag="ACG804_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFS4831782.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            17471..18085
                     /locus_tag="ACG804_000835"
     CDS             17471..18085
                     /locus_tag="ACG804_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFS4831783.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            18078..19802
                     /locus_tag="ACG804_000836"
     CDS             18078..19802
                     /locus_tag="ACG804_000836"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFS4831784.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            19799..21250
                     /locus_tag="ACG804_000837"
     CDS             19799..21250
                     /locus_tag="ACG804_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFS4831785.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(21722..23875)
                     /locus_tag="ACG804_000838"
     CDS             complement(21722..23875)
                     /locus_tag="ACG804_000838"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HFS4831786.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDREYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(23877..24923)
                     /locus_tag="ACG804_000839"
     CDS             complement(23877..24923)
                     /locus_tag="ACG804_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFS4831787.1"
                     /translation="MTQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            25073..26362
                     /locus_tag="ACG804_000840"
     CDS             25073..26362
                     /locus_tag="ACG804_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HFS4831788.1"
                     /translation="MVYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDACRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            26375..29077
                     /locus_tag="ACG804_000841"
     CDS             26375..29077
                     /locus_tag="ACG804_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HFS4831789.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            29062..29919
                     /locus_tag="ACG804_000842"
     CDS             29062..29919
                     /locus_tag="ACG804_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFS4831790.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(29990..30847)
                     /locus_tag="ACG804_000843"
     CDS             complement(29990..30847)
                     /locus_tag="ACG804_000843"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFS4831791.1"
                     /translation="MKITITLPMNHPETTIRDLLEKEWLVPRKVRHFLRIRKNVWINQ
                     QPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDEHLIIVDKPAGMKTH
                     PNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKNPFVLPILGRMLEQK
                     MIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSALTHVTVNKVLSEQT
                     QVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHALELHMIHPFTQEKIV
                     GKALPGLWE"
     gene            31058..33229
                     /locus_tag="ACG804_000844"
     CDS             31058..33229
                     /locus_tag="ACG804_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HFS4831792.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPAVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            33297..33638
                     /locus_tag="ACG804_000845"
     CDS             33297..33638
                     /locus_tag="ACG804_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFS4831793.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(33914..35668)
                     /locus_tag="ACG804_000846"
     CDS             complement(33914..35668)
                     /locus_tag="ACG804_000846"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4831794.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLSFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQCISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(35679..36515)
                     /locus_tag="ACG804_000847"
     CDS             complement(35679..36515)
                     /locus_tag="ACG804_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFS4831795.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            complement(36517..37200)
                     /locus_tag="ACG804_000848"
     CDS             complement(36517..37200)
                     /locus_tag="ACG804_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HFS4831796.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLMPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
BASE COUNT        12020 a         6557 c         7645 g        11045 t
ORIGIN      
        1 aattgacggt ttagcaccag gagcatatca gctggtagaa actcaagcgc caacggggta
       61 tgaattagat gcgacaccga tcgagtttga gatcgaaaga agtcagacag cggtggtaga
      121 attgacgaaa gcaaaccgac ttacaccagg cggtgtcgtg ttgacaaaga tcgatgacca
      181 aagcggggaa gtcctgcaag gagctgtttt tgagttacaa gatgccaatg gaaccgttct
      241 gcagtcaggt ctaaccacag gagcagatgg aaaactggcg attgacggct tagcaccagg
      301 agtgtatcag ctggtagaaa cccaagcgcc aacggggtat gaattggatg cgacaccaat
      361 cgagtttgag atcgaaagaa gtcagacagc ggtggtagaa ttgacgaaag aaaatcgact
      421 tacaccaggc ggtgtcgtgt tgacaaagat cgatgaccaa agcggagaag tcctgcaagg
      481 agctgttttt gagttacaag atgccaatgg aaccgttctg cagtcaggtc taaccacagg
      541 agcagatgga aaactggcga tagatggctt agcaccagga gcatatcagc tggtagaaac
      601 tcaagcgcca acggggtatg aattggatgc gacaccagta actttcaaga tcgaaaaaga
      661 acaagaagtg gcgatctttt taacaaaaga gaatagaaaa gttgctgata gctcagatat
      721 aagaggaaac aatccaacaa gcagtggaaa taagcatctt ccaaaaactg gagaaaccat
      781 cattagccag tttatattgt caatattggg tgtgctactt gttttcatca gtataaaatt
      841 tagaaagaaa cgaaatatat gagctaaaat aaaaaattga ataagcatag tttttaaaat
      901 caactagtac ccatcaattg aatggaaact accgatttta gaaggggtat acaaacaaat
      961 attagtatcg gagtagagaa ggttgaaccc aaccagtaaa taagtaaaga caattttgtg
     1021 ctgcgttgag aagtgaaaaa taaacctttg tagtaatact agttaataaa aaatatacaa
     1081 aaacactgcg aaaatcattc ttgagtttcg cagtgttttt tgcctaatga ctcaagttta
     1141 ttgggtaata ctttgatttt ctttctacaa ataatcagcg atcagttgta attttttctc
     1201 tagttttaat ggctctttgt caataaggag aaaaacaagt cgggtctttt gtctcggaaa
     1261 gcttcaacca actcgtgaat aaaggttacg cctccttgaa aggcgtggaa aaaccaagta
     1321 atcgatcaat caccaatttc gcatttggta gaacatgttt ggtgagctga aagtaggtgg
     1381 cgttcatgtc tgtaactaag aattctattt ctttaggatt agtgcagcta aggaaatagt
     1441 ttgttaatcg aggaattttt tgtgtaggta aattttctcg attaattttt ctgtctcgcc
     1501 atccgcggaa ataaaactca gtttatcctc aacggaaacg tgagaacgaa attcacaacc
     1561 ctcaacactc aagacagaat tcttttggaa gactttggta aatagcttct caactctttc
     1621 aatgtgcgaa taacggttgt caaagatacc taacaacttt tcgaaataaa aaataacgac
     1681 actttttcag tcagtaaaga agtgatttta tgtctgacat gatttgaaat cgagtgcctt
     1741 ggacggataa aataactttg agcgttccaa tggcttcgac agtttttaca ggtatagcgc
     1801 tgctttttta ggcgtataac cattggcata tgattatatt attcaaagtg gacaatggtt
     1861 tccttcttct tgtttttcac caccattaat ttcctatttc catctaccac agcagaacca
     1921 caatttctac agacacatgg agcagggaag agaactgcag caacgatcaa tgtttttttc
     1981 ttctgtaagg tttcgtaaga gacctctgta atcatcaaat ttttgtctat tgatctcaga
     2041 atttttttga tagaaccatt cataaagcat atcgttctct cagttgttta ttttgtggtg
     2101 atttaatcat acaagaaaac gatatgtttt tttataaaaa catgaatagg aaaaatagtt
     2161 gacaagaaaa tgacaacgcc atatgatgtt ccatagtatt tacaacctgt catagatgac
     2221 tgtaaaaaat aaaagtaaaa agaaaggacg acaacaggtg gatttttatc agtctctaca
     2281 actagatccg tttattttaa aacaaaaaat acgagaagca gcttctaaaa aagaaaagtg
     2341 catgtatatt tgttcattgt ttttacgatc attattcatc gtattgtttg ccatttgttt
     2401 tatcattata attacaacat tatttgaatc gaagcataaa ccatacgctg tggttttatt
     2461 ctgtatgttg atgagtattc gttttgttga ctttggttat aagatttccc attcgatcat
     2521 aggtttagca atcgtcatgt tctcactatt agtagcaccg tatgtccagc tgatcaaatg
     2581 gtcagttatg ggcatgttga ttcattttat tttactaagc agcatattaa tggcaaccgc
     2641 tagtgatccc aaaatgggga atgcttcttt gtacggcttt tcatatctct ttattgttta
     2701 ttcgttacct aaagattcgt tgaacaagaa tttctttaca caaacaagta gcttattatt
     2761 tttgtttttt tgttggtttt cagttctcct ttacagaaaa catcgagaaa agaacaaaga
     2821 caaaagcttg tttaaagaga tttttttgaa aggcatgtat tcgcaggaaa aaatttggat
     2881 gctcatctat gcatttggca ttagtctttt gatcgttgca ggagagtatg tcccttttca
     2941 gcgattgatg tgggcagggt ttgcattttc ttctattgta tctagctatg gattgatgtc
     3001 gattggtttc aaagaacgag cagtagaccg aatcattggc tcattgattg gatgtgtttt
     3061 atttattggt atcagccaat ttattccttt taactgggtc ggtatattag gtggtctagc
     3121 tttaggtgtt tgttctacct atagatataa aacagttttt aattcttttg gtgctttggc
     3181 aatcactgcc agtttattcg gggttccagg agcagtaacg atccgcattt ttgagaatat
     3241 ccttggggta tgtttaggaa tcatgtatat tggggtgact gaaatactta tccgaaaaat
     3301 aagagaaaaa cacggtttga atcattagat gagatcgaat aaaaaataag gaaaaagtga
     3361 agatacacat ggatgataaa ttgctatcat tccatgtgta tctttttacg gtaaatcagt
     3421 gaaacgttcg actttcattt ttaatttata ctttttacgg agttcgttta tttgagccat
     3481 catttcggat ttgtgatgct tttcgattgc ttcttcatct ttccaacggt cgatcagtaa
     3541 aagagattct ggatcttcta gtggaaagta atagtcatat ttctcgtttc cttcttctgc
     3601 acgaatcgct ttgacaatgt ttctttcgac catttcttct gcaaattttc tggcttgtcc
     3661 atttgtactt gtatacaaaa tattcactgt gatactcact aaatcccctc ctgaaaaaat
     3721 tctatcacta gtatatcacg gtgccagaaa ttattattca agatatgata cacatttttt
     3781 ccgcaatgct acggaaatat atattttgaa tagaaaacgc ttacaagata tgcttggttt
     3841 ataaaaataa aaggagtgat tgatttatga aaaaagcatt gattatttgt gcggcaggaa
     3901 tgtcatcctc gatgatggcc tcaaagacaa cggatttctt taagcaaaaa agagaagagg
     3961 tactcgtaga tgcagtttca gctacagaag gcgataatat gattaagaat agtgattttg
     4021 atttatttct gatcagcccg caaacgacga tgtttttgga taaattcaaa aaattaggag
     4081 aatctgttgg aaagcctgtt gttagtatcc ctttccaagc gtatgtccca atccctacag
     4141 gcatccagaa gttagcagag gtgatcgaag agaacatatg atggaatagg agtggatgat
     4201 aatgaaacag aaggaaaaat tgctgttgag atatttgatt gatcacaaga aggagtatgt
     4261 caccagtcaa cgtttagctt ctgaattgtt attatctgat cggacaatcc gtaattactt
     4321 gcagcggatc aaagagttag tagaaaaaaa cggaggtaag atcattgcta aaccaggtta
     4381 tggctaccaa ctgcatattt tacaaagact gacatttgac ttgtttttga gtcggcaaga
     4441 aatagtacct ggatatgcta gagaaccgca aggattttat gagtccgaag atcgacaaaa
     4501 gtatatattg aaccaattgc ttttggaaga tgccattctt tttatggatg atttggcaga
     4561 agagctttat atcagtcgtt ccagtttgac aaaggacatg caagaaatca aggagcgatt
     4621 gattccatat tcactaaaaa tcgtttctaa gcatggtcaa gggacatgga tcgaagggga
     4681 agaaagaaat cgacggcatt ttatcatgga tacttttttt ggaaaccatt atggaaattc
     4741 attgaaagaa tatttagggc aaagccgttt tttcccagac atcagttttg aagagctagt
     4801 cattatcatt ctcgatgaaa caagagaagc taagttaaaa gtttcggatt ttatcataca
     4861 gaatctgact ttacacttgg ctttggggat caaacggctc cgagaagggt ttgaaatcaa
     4921 ggaattaggc atcgaacaag aagtttctaa gcgagtagag tatcaagtgg cgcagcggat
     4981 cgttcaacgt attgaggtaa tcgcaggtgt atcgtttccc gaagaagaaa ttgcttattt
     5041 gacattacat ctcatggcta agtcgaatca caaagaaaat caaaatgatc aggaactatc
     5101 aaaggaatta gcgaaagttc tgaaaagatt gtctcaggaa tttcattttt cattagtaga
     5161 ggatctccag cttttcaatg gactactcga tcatttgtca ccgatgatga ttcgattgag
     5221 ccgaggtatt cgcattgaga acccattgac tgaggagata aagaaagaaa atcccaaagt
     5281 ctttgacgca gtaaaaaggc atttcagcaa catgccggct ttgaaaaact ataccatcaa
     5341 tgaagatgaa tgggcctatt tggctttgca tctcatggcg gcattggaaa aagaaagagc
     5401 tgcgcataaa ctacatgcat tgattatctg tgcaacgggt tacggcagtg cccaactatt
     5461 aaagaatcgc gtagtcagtg aattcggtaa aaatattaca gtggtaagtg taaaaggcta
     5521 ttatgagatc aatgaaacaa ctttaaaagg aatcgacctg attatttctt ctattgatct
     5581 ttcgacaatg tttttcaaaa ttccagtttt acatgtcagt atttttttga atgaagatga
     5641 tgttcgtaaa atacgaaagg tagttggaga atctataccc tatcattcct cagatagacc
     5701 gataccagca ttttctctac agcaaaaaaa gcagatttac accgaacagt tgtctgaaaa
     5761 atttttcaag acttatacgt acgaaccgaa aaaggaagaa attcttcatg atttgctgca
     5821 aaagctgagc ataaatgaag aagaaggata tataagagaa atgcgaaagc agatccagca
     5881 acgtgaaaat atgggacaaa tcatattcag tgatacagtg gcagtcccac atcccgctgt
     5941 tccagttgga atcgaaacaa aggtagccgt tgcattgatt ccttctggga tgcagtggga
     6001 tcaatatcaa gaaattcatt ttgttttttt agtttcgcct tcttatgtcg aaaatgaagg
     6061 aattacggtc gtgactaaag caatcgttag gttagttgac cagctaaaag tacagcagga
     6121 aatcttagct gaacctattt ttgagaattt cagcagtaaa tttatcaaac tgatcgaata
     6181 aggaggaaaa cagatggctg aaaaaataaa cagtgaaaca ctacaagtga cttcttttga
     6241 tatcattttc catagcggaa atgcacggac actgatacat gaagcatttc gctcgatgcg
     6301 taaagagatg tttgaagaag tagaagagaa gttgcgacaa gcaaatgaag agattcttca
     6361 tgcgcatcag tcacaaactc aacttctgaa agaatatgcc agcgggacaa aaatagaaat
     6421 ggaaattatc atggtccatg cacaagatca tctgatgacg acgatgacat tattggaagt
     6481 tgcacaggaa atgaattatt tgtatcaaaa aaataaatag aaaggaagga tcattgtgca
     6541 ggatacagta aaaaggaaaa tcgaattaga aaaaaagcaa cttagtttga aaaacatgta
     6601 tttcaatcgt tatctaatcg tacgttacct gactgccttt ttctttttca tgaacatgca
     6661 atggatgatt ctgcttctat cagctaaaag tttaggaagt agtttaccga tgattctgat
     6721 tttagctatt ttgcctgcag taggagaaca agtaaagctt tatcgaaaac accaaacgaa
     6781 cgttccatgg acaaagtggt attttttgtt ccagagtgtc tttaatttat tagtgattcc
     6841 agtgttgttt acctcaggat ttacattctt gtatcctttt atggcaaata acaatggagg
     6901 acagttattt gttttcattc ttgttgtaag cggtattttt gccagtgcat ttatacagta
     6961 tcgtttaaag aaaatttcac tcaaccaaga ccaacagtat atccgtatta aacaatatga
     7021 aaaagcgtta tatttaggaa aggagaataa ctaatgtttg attttttgca gaaatacctg
     7081 atgggaccta tggggaaaat tgcgcaactt aaaatcgttc gggctgtcat ggcagcgggg
     7141 atggcttcta ttcctttcac gattgtaggc tcgatgtttt tggttttaaa tattttgcca
     7201 ttaccgttcc catttttaga aggatttttt aatgcaactt ttttcaaagt tagtgacttg
     7261 tacatgatcg tcaatacaat gacgatgggg attttatcta tttactttgc cattgtgttt
     7321 gcttatgaat taacgtcaat tgaacgagat gaacaaaaat taaatgttaa tccgctcacg
     7381 ggggcattac tatctgtttt tgcattcttt atgtgtatcc ctgaattgat catgactgat
     7441 ggtaaaatca gcttgattgc ttctatcaat gagacagaaa ctgtagtaaa tggtattagg
     7501 atgggctctt ttgtcgaacg tttaggaact tcaggaatct ttacagctat tattatgtcg
     7561 attattgcgg tcgaattgta ttgtatgtgt gtcaagagaa attgggtcat aaaaatgcca
     7621 gatgttgttc cgccaggagt ttctcgttct ttcactgctc tgatcccaac atttgtcatt
     7681 gcgtttgtgg tgatgatcat caatggatta ttagttgcac taggaacgga tatcttcaaa
     7741 atgattgcta tcccatttgg gtttgttacg cagttgacga atacatggct tggtgtcatg
     7801 gtgatttatt tcttgatcca tgcattgtgg atcgtaggga tccatggagc gaatatcatc
     7861 acttctttct tgaccccgat cgtattagct aatatggcag ctaacgcaca aggcgcaaat
     7921 tatccgttgg caggagaatt caacaattct tatgtaaccg ttggtggatc aggtgcgact
     7981 ttaggattga tcatctttat tgcattcctc gcgaaatctg atcagctgaa agtgttagga
     8041 aaagcctcac ttgtaccagg attattcaat atcaatgaac caatcatttt cgggatgcca
     8101 atcgtctaca atccctattt agcggttccg tttttcttag ctccgatggc ttctgctaca
     8161 ctcgcttatt ttgccattcg gctggaaatc gtcaaaccga tgcttgcaca gatgccgtgg
     8221 ccttcaccag tcgggatcgg agcatttgtt ggtagtggtg gtgattggaa agctgctgtg
     8281 ttagcagtca tttgtgcaat catcgcattc attatctggt tcccatttat caaattctat
     8341 gataataaat tattaaatga agaaagagaa aaggcagcag aattagctag tgaaaagtta
     8401 aaatgatttc taagaaaaaa ggaactgtga caaaaaatca cagtcccttt ttttcttaga
     8461 aatgggaaac cactagtata taaataccat tattcttcaa tcaaccgctt cacgattgca
     8521 taatcccctt cataaggttc atctacacca ttgatttttt gatagggatc cacgcctttt
     8581 cccgcaataa cgactgaatc ttgcggagcg ctttctgcta aagcgcgtcg aatcgcttca
     8641 ggacgatcca tttcataatg aacgatcaaa tctggattag taattgcttc attgatttct
     8701 tccgcgattt ttttcggatc ttcaaatgct gggtcatctg ccgtcaaaaa ggcgatgtca
     8761 gctgtttctg atagcacttt tccaaaatca tgtcgacggg agattgcttt gtttcctggg
     8821 ctgcctaata caacaattac acggccatct ggatgttcat ttttggcaaa tttcagcaat
     8881 gttttcaagc ttagataatt atgtgcatag tccacataga catgcgctcc attggattgg
     8941 atcaattgat ccattcggcc tggtacacga gcttctttta atccgtcttg tgcatcttga
     9001 ctggaggcac ctgttagtgc tgcggcaatg atcgcactgg ctgcattttc ttggttgaat
     9061 cctccagcca gcaaaatatc ataagcagta tcgcagatag ctaagcgatc ttcatgagaa
     9121 gataaagtaa aaccgtgagt acctttatct gaacggatca cttgataatt gctttcttcc
     9181 gaacgaccat aagtgatcgt tggaatctgg aatagatcgg ctgtttccct aagtaaatca
     9241 aaatagtcac tttcatgatt taaaacaact gtttttgaat tcaagatcaa ttgtcgcttg
     9301 caatagaaat agtcatcaaa tgtcggatgt tcgatcggac tgatatggtc aggcgagata
     9361 ttcaagaaga ttccgacatc taaagtcaag ccgtatacgc gttgtgtttt gtaagcttgt
     9421 gaagaaactt ccatcactag atgagtcata ccattttcaa ctgcttctga catcatacga
     9481 tataaatcta atgactcagg cgttgtcaaa tgggatttga aatatgtttt gccatctaac
     9541 gttgtattca tagtagaaag caatgctgtt tttttatttg ttgtgtgatc caagattgct
     9601 tttgtaaagt acgcagcagt tgttttacct tttgttccag tgaatccgat cactttcaat
     9661 ttattttgcg gatagtcgta aaaagccata gcaagaagcg ccattgcttt acggatatcc
     9721 gttacgatga ttcctactgc tgaattttcg tatggttgtt ctgatacata atattgaata
     9781 ccctgttcga ttgctgaatc caaatattct tctttgaaat tcattccttt acagaaaaac
     9841 aaagtagaag catcagcttt tcttgaatca taacttaact gaagaaattc agctttttct
     9901 ggtacatcaa gatgccagcc tcttgttgaa acaaattctt ttaatagatt ttcttttaat
     9961 agtaaatgac ggatgtcttc taaagagaag ctcattgatt gatccctcgc tttattcaat
    10021 ttcttggttt attatagcac actcttttta atatatcgtt tgtttccgct atgacaaaat
    10081 ccagctttat tcaaattttc ttgacacagg ggacaagcgg atgagtattt tcataaacaa
    10141 tgaactgact gtaatagata ggagaacgaa tagtgtctcc aacaatccaa aaacataata
    10201 attcaaaaag acgataagac tattggtaag taaaagtcct tgcggcattg gaagccgaaa
    10261 aaatttgtgg aaaataatcg gcggtatcgt tataccgcca tttgaggccc cgactgtgta
    10321 caatgtgtaa accccaagac tgaacaaaag acttcctgaa atcagtgaaa agaaatgtga
    10381 ggagatcatt tccacttttg gaacaatctc taaaacaaca ggaaaaagca gacttcccgc
    10441 tacagtctta aaaaatactg attttcctaa taggacagcg gctagaagca gcatcataag
    10501 attgatgctc caaacagtaa ctgagcgttg gatagaaaag gccgtttcaa ctaaatgtcc
    10561 gatggcgccc actccggcgg aagctatatc gtgagggagc aagaaccaat tcaatccaac
    10621 tgtgataaag aaaagaccta aaaatataac gggtagtttt tttatttctt gtgtcattga
    10681 tatctcctat aaatgttagc cataaaaggc tgtatatttc tttactttac caaaaaaacg
    10741 aaaccgaatt caaaaaaaca attgttctta taaaagttat ataaaatcga ttgccagttt
    10801 ctgttttacc aattaaaatg atagtaatgt tttgtagaaa gttggaatct gaccgatgga
    10861 taatcaaaga aaaccagcat tagatcaatt aacaccgcaa gaaaaaatgg cacgaggctc
    10921 tgcttggatg accgccagta atatcatttc aagattgcta ggcgctgtct atatcattcc
    10981 ctggtatgct tggatgggcg aaaatgctaa ggctgccaat ggattattca atatgggata
    11041 caatatatat gcattgtttc tactgatctc tacagcagga atacctgctg cgattgcaaa
    11101 acaaactgca cgctataatt cattgaatga atatggcact tcacgacgat tatttatccg
    11161 tgcattacag atgatgggcg ggttaggcct gttgtttgct ttgttcatgt acatcgcctc
    11221 tccttggcta gctcatgctt ctggtggcgg agaagaactg attccaacga tgcgttcttt
    11281 gagtatcgct gtattggttt ttccttgtat gagtgtgata cgagggtatt tgcaaggcaa
    11341 tcaagaaatg atgccttatg cgctgtcgca gattgtagaa caggtggcac gtatttttta
    11401 tatgctattg gctacattca tcatcatgaa agtcatggat ggtgactatg tgacggcggt
    11461 cacgcaatca actttcgcgg catttatcgg tatgctagca agtattcttg tccttttgta
    11521 ttttttgaag aaacatcaag cgtatacatc ggcgtttatt cactacagcg aaaacaaaat
    11581 aaatattgca acgaaggaat tgttgttaga taccgttaaa gaagcgattc cgtttattat
    11641 tgtgggttca ggggtaacga tcttcaaatt agtcgatcag ttcactttta tgaagatcat
    11701 gtctgcatcc accgagtatt ccaatgcaca gttactggat cttttttcga tttttagtgc
    11761 caatccagat aagttgacga tggtagttat tgcattggca acatcgatcg cgtctactgg
    11821 gttaccgttg attacagaag ctgttacgtt gaaagatcga gtaggtctgg caaaattgac
    11881 aagcggaaat ttacagttgt tttcattttt tatgtttccg gcgacatttg gtgttatgtt
    11941 acttgcctat ccgctaaata cattatttta tacaccggat tctctaggaa gtaatgtact
    12001 gatccaagca agttttgtag gactcttcct aggactatat atgctagttt ccaacatgct
    12061 gcaaggaatg tttgaaaaca aggcggcaat taattatttg gttattgggt ttctagtgaa
    12121 actccttctt caatacccag ccattcgttt atttgaagta tacggccctt tattggcgac
    12181 aatgatcgga tttgctgtgt cttgtacctt gatcttaaag agaatccatg aagtagcccg
    12241 ctttaaacca agttttgtct ggcgcaggac attgctgatc tttattctta ccttgattat
    12301 gcttttggct tcgtggatca caaagatgat ttttggtgct tttttaaacg aagatagcaa
    12361 attccagtct ctattgttga ttcttgtagt agcaggtata ggggctttag tgtatggtta
    12421 tttagctttg aaaatccgct tggcagaaag actactagga ccaggaatag cgcgtttacg
    12481 acataaatta aaaataaaat aagtgaatca gaagagctag attgatgctc ttttgaaatg
    12541 ggggaaacgc atgcgtttag ataagttttt agcagatatg ggacttggca gccgcaaaga
    12601 agtcaaagga ttaatcaaaa aaggaacgat cgaagtcaat ggacaagtgg tgaaaagcga
    12661 taaagcgcaa gtaaatgaat tcgaagatgc ggttacttat ttaggagaaa tcattacgta
    12721 tcaaaaagat ttttactaca ttttgcataa acctgcagga gtcatttctg ctactcagga
    12781 taatcatgat caaaccgtaa tcgatttatt ggaagaccag gattatcggg aagatctttt
    12841 tccagtcggc cgattagata aagacacaga gggcctcttg attttaacga atgacggggt
    12901 gtttgcccat cagttactat cacctaaaaa acatgtggag aaagaatatc tagctgaggt
    12961 tagcggtata atgacagaag aagatatccg tttatttgca gaaggactga ttattgatgg
    13021 cgatgagcag acattgccgg caaaactcca aattgatcaa gtagatcaag agacagaaac
    13081 ttcaattatc cgtctgattt tgcatgaagg aaagtttcac caagttaagc gaatggtcaa
    13141 agcagtagga aaagaagtct tatatttaaa aagaatccgt atgggaaaat tttggctgcc
    13201 taaagatttg aataaagggc aatatcgacc catgaccaaa gaagagctag aacaagtgag
    13261 agaaaaataa ttgaatggat agctaaaaga ataagcagag tagttgtagc gccatctgaa
    13321 aagcagactt gtccgtctga ctttcggatg gcttttttgt gaaatttcgg cttatttccg
    13381 tagaagctac ttctggaaca ccgtttgttc ggaataaggg actgtgacaa gacttttgtt
    13441 acagtcccca ttgttccttg tgactcagag ttagatagta aggacacgat ctccctaata
    13501 ctcaggccaa aacgctgaat tcacaacctc tgataaacgg tgttcaatca gctgaccctc
    13561 ggtattagct caaaaaacgg caaaatatga ggaactattt tcccgttttt ttctctaata
    13621 ctcaggccaa aacgctgatt tcacaacctc tcctatactt tgtttcattt tccctatact
    13681 ttgtttattt attctcatta ttgaaagcgc tataattacg ttgcgaatga atcgaaaggg
    13741 gtttttagat gaaaaaacga aaggggttca atcatttttt tatgaatcta tggcgttata
    13801 aagcacttgt cctgatggct gtaccgggta tgctttggat gatttttttc ttttacatac
    13861 ctgtaatggc gaatgtcgta gcattcaaaa attttcatat ttcagcagat gggttcttgg
    13921 ctagcttgag ggaaagtcct tgggtgggtt gggaaaattt caaattttta ttttcttcgg
    13981 atcaagcatt tctcatcact aaaaatacaa ttttatataa tgtagcattt atccttttga
    14041 atctgctgat ctcagtcgta tttgcaatca ttatgagcga gttgagaaat aaacgactcg
    14101 ttaaagttta tcaaacgatg tccttactac cttattttct atcttgggtc attatcagtt
    14161 actttgttta cgctttttta agtcctgaca aaggaatatt caatcagtgg atcactggac
    14221 atggaggaga agctgtcaat tggtataatg aaccgaaata ttggccgttt atcttggtgt
    14281 tcattggtac atggaaaggg attggttata acagcattat ttactttgca tctgttatgg
    14341 gaatcgatcc gacttattat gaagctgcta tggttgatgg agctagcaaa tggcagcaga
    14401 tcaaacatgt gacgatacca caacttattc cactaatgac gattttaacg attttagccg
    14461 taggaaacat tttccgagct gattttggcc tgttttataa cattcctagg aattccggtg
    14521 cattatatga tgtgactcaa gttttggata cgtatatcta caatggcctg acatccacag
    14581 gagattttgg tatgacggct gctgcaggac tttaccaatc agttgtcggc tttgtcttgt
    14641 tgatgatcac aaatacgatc gcccgacgtt ttgatagcga ttctgcatta ttctaaggag
    14701 gaaaaaaatg aaaaaaaaga aagtggagag agtccaagtc cgctctttca ataagacggc
    14761 taattttttc tctaatataa tgattgcact ctttgctatt tcctgtattt tgccatttat
    14821 atttgttatc gccatctctt ttaccgatga gtccatattg tcgactcacg ggtacagttt
    14881 ttggccagaa aagttcagta tatttggtta tacgtacttg ttcgaccaga tgcaggataa
    14941 aattttccaa gcgcttttcg tcactgtact tgttactgtt ttaggtacac tgatcaatag
    15001 cacggctact tctttatatg cttatgcgat ttcacggtca aactttccat tccgtcgttt
    15061 ttttaccgtt ttttgtttga ttacgatgtt gttctcacca gggatggtgg ccaattatct
    15121 tgttatgaca aatcttcttc agttaaaaga tacgatttgg gcattgatct tgccaatggc
    15181 tgtcagtccc ttcaatatta ttgtgatgcg cacattcttt aaacgttcgg tctctgattc
    15241 gattattgaa tcggcacgga tcgatggagc tagcgaactg cgaatatttg ttcagatcgt
    15301 tttaccgtta gctgttccag gtattgcgac aatcagttta tttgccgcat tgggttactg
    15361 gaatgactgg ttcaatgctt tactctacat ccaagatgat aagctagttc cactacagta
    15421 tcttttgatg aaaatccaaa gtaatattca atatctgaca caaaattcag gagcaggaag
    15481 ccaattgaca ggcggattag cctcagttcc aggagaatct gccagaatgg cgatcgtagt
    15541 catctcgacg ttgcctattg cgatcagcta tccatttttc cagaagcatt ttgtcaaagg
    15601 tctaacaatc ggcggagtaa aagaataaag aaacaaaaat ataaatcata aaattaggag
    15661 gaagaaaaat gaagttatgg aagaaactag cctttacagg tgtttcagcg ttgttgttgg
    15721 gaacattagc agcatgcgga ggttctggtt ctaaagacca ggcagaagct agcaattcgg
    15781 acactttgca gatgtatcaa atcggagata aaccagataa tttcgatcaa ttgatggaag
    15841 tagcaaacaa acgaatcgaa aaagagatcg gtgtaaaagt caatatcaat tacattggct
    15901 ggggcgatta cgaaaagaaa atgaacgtca tcatttcttc cggggaaaat tatgatatcg
    15961 cctttgcgaa caactatgtt tccaatgccc aaaaaggagc ctttgctgat ttgactgaat
    16021 tagcgcctaa gtacgctgaa aaagcttata atgatttaga tgaagcatat attaaaggaa
    16081 atctggtcaa tggaaaatta tatgctttcc cagtcaatgg aaatgtcttt gctcaacaag
    16141 tacttacttt taacaaagct ttactagata aatacgatct ttcaattgat ggaatccaat
    16201 cttacgctga tgcagaaaaa gtcttgaagg aattccatga aaaagaacca aacacggcag
    16261 cttttgccat tggacaaggc ttcaaagtcc aagggaactt tgattatcct ttagggaata
    16321 cgttaccatt tgctattgat ctggatggag atgattcgaa aatcatcaac caatacgata
    16381 atgaaacgta tatcggactg ttacgtacaa tgcatagctg gtacaaacaa ggactcattc
    16441 caagtgacgc tgcaacgagc aataaggatt atccactaga aggaaatact tggctaatgc
    16501 gtggagaaac acaaggaccg tatgattatg gcgatacaat tttgacaaat gcagcaaaac
    16561 aagaacttgt ctcaaaagca attactgttc cactaaaatc tacagctcaa gcacaaatgg
    16621 caaattttgt cgtatcaaat acttcaaaaa ataaagaaaa atcagtagaa cttctagggc
    16681 tgcttaacag tgatccagaa ttattgaatg ggcttgtttg ggggatcgag ggagaagcat
    16741 gggaaaaagt cgatggttca gatgataaaa tcaaattgct agatggttat cagccaaata
    16801 cacatatgtc tgcttggaat acaggaaaca acaagattct atatacacaa gagtctatta
    16861 cggatgacat gattgccaaa cgtgatcaat cgattgctga tgcagaaact tcaccgattt
    16921 taggattcag cttcaacact gacagtgtca aaacagaatt aagtaatatt tctaatgtca
    16981 tgaatcaata tttagatgga ttgaatacag ggactgttga tccagatgaa acattaccga
    17041 aattgaaaga cgctttggac aaggctggct atgataaggt attgaaagaa atgcaaaaac
    17101 aatatgatga gttccgacaa gaataataat gaataaagac aaaggggttg tgacaaaaga
    17161 cgtgtcacaa cctcttgttc cgaataaacg gtgttcaaaa gccagtttct cggtattaag
    17221 ctaaatatat gtaaaaatgt ggaaagccat attcacaaaa tttttcttac tactcgaaac
    17281 taagcggcta tttcacaaac tcttggtaaa cggtgttcaa tcagctgacc ctcggtattc
    17341 gctcacaaaa cgacaaaata tgaggaacta tttttccgtt tgtttctcta ataatcaggt
    17401 caaggtgctg attgcccaac ctttttttgt ataatgagaa agtataaact taatgtttgg
    17461 aggagaagat atgttaggga aggttttgga agagttattt atccggatct gggtcattat
    17521 aaaactaacc ttgtatttct ggatatatac atttgccggc gggatcatct ttggattagg
    17581 tgcggcatgg aaaacagtca atgaactatt ttatttgtac ggattcgagt ataaagaaat
    17641 cacaataaaa agaggctgga atatatataa aagaaatttt ttaagaggca atctgctatt
    17701 tagtttattt ttatctggta ctgctttatt gagttacaat ttatatttat ctgttcaaat
    17761 caaagggctc atttttttag ctattgattt tattttactt tttgccttgc tctgcctatt
    17821 tgctacttat caatacagta tgattttaga tagtgaatat acgatctctg ttcctaatct
    17881 gctaaagcta agttttattt cggttttttc cagcttttcg tcttttctaa aaataattat
    17941 tggtagcggt ataattttag gcgtgacttg gcaattcaaa ggattgatcc tgtttggtgt
    18001 cattggtctt ttgacggttt ggaatggtac gatgacaaca cattggcgtg aagaattaga
    18061 taaacagttg gaaagttatg aataagtttc ggattctatt ttcaaaagga accttactaa
    18121 atcgtctgtt gcggaaatac gcggttatca tgatcggtgt aacgatgact gctaccgtta
    18181 tttttagtat ccatacttgg gaacaaaatc aaaaacaggc agaaaacatg acaagtgatg
    18241 ccgttcaaag cacaagcaga atgctgaatg ataaaacaac cttgagtagg atcatcaaaa
    18301 accagcttgt agggaattcc gaaaagatcg aaaatgtgac gacctactta acaaaaccca
    18361 tagatcagta tctgatgtat gtatacgaac agcaaaacag taccgatgaa ttagtttctt
    18421 tcccaaatca aatcaaagat ctctacgcaa attatgaaga actaagtgcg atatatatcg
    18481 tgttgaatca actaccggag tattatgaat cttctagaga aaacaaaggt ggggaaataa
    18541 aaaaggggac accaaaatta ctagacgcct tttatatcaa gttgcctatc acacaaggag
    18601 gagctgagtc aggaagtatt tttattggtt ttcaaaagaa agaactagat atgattttag
    18661 aaaatctaac gtcattcaat ggactctctt tatacatgat ttctggaacg acaaatcgac
    18721 tatacacatt ccatgataat aaaatagcta aagaaacgtt tgaaagacaa gaaatgatca
    18781 tcacagagag tctgaagaaa aattcacaat tgccgattga cgatctggaa aaaaacaatt
    18841 ttgttcaaca ccaagaactg tctgatgatt atcgtatatt agctgtacta gataaaaaaa
    18901 gtgtaaaaat cgaaacggga aaaaatcttg ccccgctgat cattggtatc attattttag
    18961 acaatatact gcttatcttt ctttataaaa cattcaaacg atattcacag caagtatcta
    19021 tcgtcatgca ggccatggat caaacagcag cagggaattt agagacgcgg atcgacataa
    19081 caaacacgga atatgaactg aaggaacttt caatcggtat caacgaaatg ttggatagca
    19141 tcaatcagtt tgtagaagac atctacaaat tagaaatcaa acagcaagac gcacatatgc
    19201 gggcgcttca agcacagatc aatccacact ttttatataa tacattagaa tatatccgaa
    19261 tgtatgcaat cagcgaagga agtgaagaat tagcagatgt tgtgtatgcg ttttccgctt
    19321 tgcttcgaaa caatacgaat caagagaaaa cgatcacttt aaaagaagaa ctggactttt
    19381 gcgaaaaata tgtctatttg tatcaaatgc gttatcctaa tcgagtagcc tatcatttta
    19441 tgatcgatcc tgatttggaa aagatcgaag tacctaaatt tgtgatccag ccattagttg
    19501 aaaattattt taaacacggt attgatttta ctcgattcga taatgcgcta agtgtcaaag
    19561 tcttgcagga aggcaaacgg gtaaggatca tcatcaaaga taatggaaaa gggatgactg
    19621 aaaaacggct aaaacagatt gaagaaaaac tgtctcatcc taaagtggaa cttcacggtt
    19681 ctatcggtct gcaaaacgtg aatgaacgtt tacgtgccag cttcggcagc agttattata
    19741 tgtcgcttga gaataatgag acaggtggac tgaccgtttc tattacattc aaggagggat
    19801 gagcgtgtat caagtgttat tggtagatga tgaatacatg attttgaatg ggttaaaaaa
    19861 gataattgat tggcaaagtt taggctttca aatagtagca acagcagaga atgccaaaga
    19921 aggactagct gtacttgaac agcgacagat tgatttagta gtaacggatg tgacaatgcc
    19981 agaaataaat ggactggaat ttattgaagc ggctcaaaaa gaacgtcata attttgaatt
    20041 tatgatttta tcaggatacc aagaattcga ttatttgaaa ggaggtatgc aattaggcgc
    20101 cgtgaattat ttgatgaaac ccgtgaataa gttcgaattg gttgaaagcc tcaagaaaat
    20161 caaaacacgg ttagatcagc aaaatgaaca aaaaaatcaa caagaaatct atcaagaact
    20221 gttattcagt caatggttga atgaagaatt ggatgaaata agtgaagaag aaataatagg
    20281 acaaataagt gagaagcagc ataggatagt attgattcaa ctggcaagaa ctcatgatac
    20341 tcttatcaat agatggttgc aagaacggca acaaatcttt tactatcaac gaaattacgg
    20401 agaccgtgta ttgatcacgt tgttgttgga ggcagatgaa gttgatggct tctgttgttt
    20461 tgttcaagaa aactttcctg atcaggaatg gctgatcagt atcggggaag agacagattc
    20521 tttggacaaa atccctgaaa cattccaaca agcgaaagac aatctacagt tgcatcaatt
    20581 ttatggagat aaagacgagc atgtttttta cgcagtacaa gcagaaacaa aagatcaaac
    20641 catcgatttt tcaagtttca gacgcgtgct gcaaaataaa caattggaag tcgctcaaaa
    20701 aatgatcact gatttttttg aacagtttca gttagcagcc atgatgccgg aagatatacg
    20761 atattccagt tttttactgt ttatggagat tcaacgggaa ttgattgatc tggaagatga
    20821 ggaatattta caaggaatcg aaaaaatcca tcaggcaaaa acggtgcaag aacttcagca
    20881 gctacttctg tcattcatca aaaagcatca gagacagaaa aagtacagtg acaatgtgga
    20941 aaaagtaatc gtaatcctgc accagcatta tcaagaacca cttacactca aagaagtgtc
    21001 agaaaacctg catttaaatg tcatgtatct aggacagctg ttcaaaaaag aaacgaaaaa
    21061 aagtttttca gcttatttga accatttacg tatggaaaaa gcgaaacaac tgcttttgca
    21121 cagtaatcaa aacatcaatg agatagcaag tgagattggc tacaacaaca ccacgtattt
    21181 ctctaaatta ttcaagaaaa tcgtcggcag atcccctaaa gagtaccgag aaaacagtgg
    21241 agaatcataa aaaaaaagcc aatgtaatga aataacttat aaaaaattgt ctagaaatct
    21301 aattttgggc tgttcttatt acttgaggca aggcagcttt ttcatgacct ctcgataaac
    21361 ggagttcaaa agccagtttc tcggtattaa gccaaattta tgcaaaaatg tggaaagcca
    21421 ttttcacaaa atttttctta atactcgaaa ctaaacagct ttttcacgac ctctccacta
    21481 aatggtgttc aatcagctga ccctcggtat tagctcaaaa aatggcaaaa tatgaggaac
    21541 tattttgcca tttgtctctc taatactcag gtcagaacgc tgatttcaca acctctcaat
    21601 aaacggtgtt caaaagcttg catctgcggt aataagacca accaaacgaa aaatatgagg
    21661 atctattttt gcttggctgt tcttattact tgatgcagga cagctttttc acaacctctt
    21721 gttaattata gtttgataag gaaaaaggca aatcttttgc ttgatatttc ttagggtgag
    21781 ggatgatccc taattggtaa gagatcgtgc cgcctttcag caaatcttga tgggtaaaat
    21841 ataatttcgt atattctctg tccatccgtt tgattttatg gataaattgt tgctgcggcc
    21901 gattaggcgt tgcttcaatc gtcaattcct ttccatttga caaaagcaaa acagccttgt
    21961 caattaatgg cataccgata acatattcac cggttccagg cgtgacagga taaaatccca
    22021 gactattgaa gatataccaa gcggccatac ttccattgtc ctcatctcca gggtaaccca
    22081 ttggagaatc gtcgaaggtc tgagtcatca actgtttaag cagtggctgt gccatttcag
    22141 gttgtcctat ataactgaac aagtaaggat agtgaaaact tggctggttt gaaatagcta
    22201 attgtccaaa ttctatcgcg gccatctcac tcatttcgtg gatctcaaaa ccatatcctc
    22261 ctgggtcaaa cgttgggggc tgattgcaca gctcaatgag tttttcttta tatctctcac
    22321 tgccaccata ttttccgatc agtcctgaaa aatcgtgata aacagcaaag ctgctttgcc
    22381 aagcacttcc ttctgcataa tcttgtcccc aacgattagc tgaaaatggt tctctgaact
    22441 tgccatcttt atcttttgaa cgcataaatc ctgactcata gtcaaagata ttttgatagt
    22501 tcaatgattg ctgctgatat ttcttcgtca tttcctcttc ttctagtacc ttggcaactt
    22561 ggctaataca aaaatcgcta taagcatagt ctaatgtgtg attgactgat tcgtggtagt
    22621 gattaggaac atagccatat gtcaagtaat cttctgttcc ttggcgtcca taatttggat
    22681 gtttgctttg aaccgtagca cctttttcca ttgccgttag aaattcaggc atcaagtctc
    22741 gtcggatatc ttttacagca gcatctgcaa tgaccgcatc gatcaatgtc ccaggcataa
    22801 gtccacgttc atcaggagac agccattttg gcaaatagcc actttctcta tagctgttca
    22861 aaaaaccttc cagcatttct tcgtattttt ctacagcaat caaagaataa agaggataaa
    22921 ccgttttata cgtatcccaa aacccattat ttgtatagag aacaccaggt tttatagatc
    22981 gactagtcgt atcatagtgg attttttgcc cactaggatc aatttcataa aatgtttgtg
    23041 gaaataaaaa cacccgatat aaattatgat aaaacgtccg caattgttgt tgatcatggt
    23101 gtgtgagctg tatacgatca aaataggact gccattgttc ttgactgtga gcaaggtaag
    23161 tctctttgct ttggttttgt tctagttcca ggttataagc tgcttgttcc gagctgataa
    23221 aagatgtccc aaatcggata gtttgttttt ttgtctgttc aaaatacaac gggatcgagt
    23281 cgctattttt gttggaaaca gctaactcat caattgttaa aggatattca aatctcaata
    23341 taaaataaaa agaaaaatca ggatcttctg aaccagcaaa atgtgtgatt tttccttcca
    23401 ctgtgtaagg atctataaca aagagctgat ggcgtcccgg aaaggataaa agtaaaccgc
    23461 tgtcattttt gctgtaatca atagataaga ttccgccata catgctaggt atcaatgtag
    23521 aacagatgcc ataacgtaat tgacagatcg acagatgagt cgggcaaaat atactttctt
    23581 ctgggcggta agaactttga gcatggaaaa gggtgttctc ctgtagtttt ccattgatcg
    23641 gcgtaaacag catatgactg aaatcaccca tccaaggact tggttgatgg gtaagacggt
    23701 agccttgaaa aacgcggtca tcaggatgaa accaccagct gccgttttga tccgtagttt
    23761 gcggtgcaaa ataattcatc ccaaaaggaa cgccagtata aggctggcag ttcccattag
    23821 agaaatttgg ctgattcgct gttgcatgtc tagtatctat ttgaccgata ttcattttat
    23881 ttctcctttg ttgattgtct tttgatgaat gaaactggaa atttactatc ggatggtcga
    23941 tcttttgtct ctaaccaagt gaccaaagca tctcccgcaa gcttacctaa ctgttcaaaa
    24001 tcttgtgcga tggttgtcag tggcgggtca acaagagctg ctgcttggat atcatcaaat
    24061 ccgataattg aaaaatcttc agggatatga taaccatgct gtctcaagag attcatggtc
    24121 tggatagcga caacatcgtt ttcacaaaca aaagcagtta cttcatactt agtgatataa
    24181 gaaagcaatt catctaatgt cgcgcttttg tcatccagtg aagtgtggaa agtcaaacca
    24241 gctttgtcca atgcttcaag gtaaccaagg taacgctgtc gaacggattg tggatgagtc
    24301 tgcgtaccaa acaaataagc gatttttgaa tgtccctgtt cgatcaaata agaggcagca
    24361 agcgcaccgc cttggaaatt atcggaaaga acggtaggaa aaggtaactc atagattttt
    24421 ttatctaata tgacgacagg gaattctttc aatgaaagct caaaaagtaa gtcaagatgt
    24481 tgttctgtat caagagcata ataaatcaat ccgtcaaatt cattgattag ctcttttgct
    24541 gttttatttt gtagaaagtc aagcgtcgtc atcatgacat caatctgttt atcttgcatc
    24601 acagggttca atcccttgct aaaatcacca acagacaaat cagcgacata tggaagaaga
    24661 aacagaatcc gtcgtgtttt tgtaggagaa gcaagaatct gttccggaga agcggattta
    24721 acgaaactgc ctttcccgcg aacgcgataa ataagtccta attgctctaa ttcagtcaat
    24781 gcacgtttgg aagtgattct gcttacttta taggtacgtg aaagttcttt ttcagttggt
    24841 agttggctgt ctacaggtaa ttcaccagtt aaaatagccg tttgcaaatc attaaatatt
    24901 gtctggtaca atggttgagt catataaaca cctcttaatg atatatcata ttcaaataat
    24961 accataatgg atgaaaaagt aaataaaaag atattttttg aaagcgtaga cataattggc
    25021 tgtatgaagt ataatcttta aagatatatc aaatagaaag aaggttttat tagtggttta
    25081 taaagatata ccaaaatcgg tgcagaaatt tatggaagat atcacacaaa aatgtgggga
    25141 tatccatgcg gactgggcaa agaattttac agcagcattt gccaatactc tgttgacaac
    25201 agtcaaaaag caaaatgacg gaaccacctt tttattgacg ggagacattc cagcgatgtg
    25261 gttaagagac tctactgcac aagttcgtcc ttatttagtg attgcaaaag aagatgagga
    25321 attagctgac atgatcagcg ggttagtcaa aaagcaattt ttttatatca atatcgatcc
    25381 atatgcgaat gccttcaacg aagaagctaa cggtgctggc caccaaacag atcatacaaa
    25441 aatgaacgat tggatctggg aaagaaaata tgaaattgat tctttatgct acccaataca
    25501 gttggcctat cttctttaca aaaatacagg aaaaactgat caattcaatc aatcttttat
    25561 tgaaggtatc aaaaaaatct tggacgtgtt caaaacagag caagatcatg aacactctcc
    25621 ttatacattt gtacgagaca cgacaagaaa agaagatacg ctgatcaatg acgggcgagg
    25681 tgcaaaaaca gcttttacag gaatgacatg gtctggtttc cgtcctagcg atgatgcttg
    25741 ccgttatgga tatctggtac catccaatat gtttgcggtg gtcgtgttag gttatgtgga
    25801 agaaattttt caaacgatac tcgatgataa agaaattgta cagcaaacac agaaattgaa
    25861 gaaagagatc caagagggga ttcagaatca cggacgaacg gttaatcaaa aagggcaaac
    25921 gatttatgca tatgaagtag atggaatggg aaacgccaca gtcatggatg acagtaatgt
    25981 gcccaatctg atcgccgcac cttacttggg atattgttct gaacaagagg aagattatct
    26041 gcaaacaaga agaacattgt tgagtaaaga aaatccatat ttctatgaag gaaagtacgc
    26101 aaaaggaatt ggatcctccc atacgccaga aaaatacgtt tggccgattg cattagctat
    26161 ggaaggaatg acaacgtcag acaaatctga aaaagagcgg atattgaatt tacttgtagc
    26221 aactgacgca ggaacacacc ttatgcacga aggattcgat gtgaacaatc ctgaaaatta
    26281 tacgagagaa tggttttctt gggcaaatat gatgttttgc gaattagtca tggattactt
    26341 tgatattaga gtagaaaagt aggaggtatc gtaaatgaaa aagaaagtat atatcatttc
    26401 tcatagccac tgggatcgtg aatggtacat ggcttacgaa cagcatcaca tgcgactgat
    26461 tgaattgata gacgatctac tagagctatt tgaagttgat ccgtccttca acagttttca
    26521 tttggatggg caaacgatta ttttagatga ctatcttcaa gtaaggccag aaaaaagaca
    26581 ggcaatccaa caagcaatca atgaaggaaa attgagaatt ggaccatttt atatcttgca
    26641 agatgatttt cttatcagct cggaatcgaa cgtgagaaat atgctgattg gcatggaaga
    26701 aagccgtaaa tggggaaccc ctgtcatgtt aggctatttt cccgatacat ttggaaatat
    26761 gggacagacg cctcaattaa tgaaacaagc tggtatttca gcagcagcgt ttggccgtgg
    26821 tgtaaaacca attggctttg ataatcaagt tttggaagca gaaaactatt cttcccaata
    26881 ctcagagatg tggtggaaag gccctgatca aacagcaatc tttggtctgc tatttgccaa
    26941 ttggtatagc aacgggaatg agattccagt agaaaaagaa gcagctcttg ccttttggaa
    27001 gcaaaaatta gcggatgcag aacaatatgc ctctacgaac cacttattga tgatgaatgg
    27061 tgttgatcat caaccggtac aaaaagatat atcaaaagca atccatctcg caaatgaact
    27121 gtttccagat tacgagttta ttcattctaa ttttactgac tatctggaag cagttcaaaa
    27181 agatgtgcca gaagacttag gctcagtaga aggagaattg acaagtcaag aaacggatgg
    27241 ctggtatact ttagccaata cagcatctgc tcgggtttac ttaaaacaat ggaataccaa
    27301 ggtccagcga cagctagaaa atattacaga accacttgcg acgatggctt atgaagttag
    27361 tggaaactat ccccatgatc aattagatta tgcttggaag acattaatgc aaaatcatcc
    27421 tcacgacagt atttgcggtt gttcagtcga ttctgtccat cgggaaatga tacctcgttt
    27481 tgaaaaagca gatgaagttg gaaagtatct tgcacaagat tccttagaac agctgaccgc
    27541 agcaatcgat acgaccggat tcccaaaaga cagctttcca tttgtcattg taaatactgc
    27601 aggaatggat aaaactggtg aagcagaaat aaccatcgaa ttagaaagaa aaagattcgc
    27661 tgaaggaata cctgaacaac tatatcaaga gttagaaaat ttgcctaaac gtaagtatca
    27721 tgtagaaaca aaaagtgggg ccactatacc agctatttta tctgaagaaa ctgtccaatt
    27781 tggttatgat ttgccgaaag accgtttccg tgtgccatat atggcaagaa tgatcaaagt
    27841 gactttacca ttagaaaaca tgccagcatt ttcttgggaa acattcgcgc ttgtagaagg
    27901 ggaagcgaaa gcagaagaaa aggaaacaat gattcatcag agtggacgaa tcatcgaaaa
    27961 cggccctcta catttgacga ttgaaaaaaa tggtaccatt acaatggaag atcgcaaaaa
    28021 caaacgaaag ttgaataatc tgcatatttt tgaagatatc ggcgatatag gaaatgagta
    28081 tatctttaaa caacctttct gtgatcagcc aatcctatcc agtaacaaag aaaactctga
    28141 agtaaaagta ttagtagata caccggaaat agcaaaaata agtattctac aggaaatgga
    28201 aatccctgtt tctgcagacg agcgtttaga aaaagaacag cagatggttg tggaatttcg
    28261 ttatcgaaaa gcagaacgat ccaaagaaaa acgaatcctt caaataaaaa caatcatgac
    28321 aatcagaaaa gatagtaaaa aaatcgactt tgaaacgact ctcgacaatc agatgaaaga
    28381 tcatcgctta cgtgtcttgt ttcctacaaa gttacatgtg gaacatcacg aagcagatag
    28441 tatttttgaa gtggtgaagc gcccaaacca tgtgtctaaa agttgggaaa accccacgaa
    28501 tccgcaacat cagcaagcat ttgtcaatat tcatgatgaa gagtacggtg taacagtcgg
    28561 aaactttggt ttgaatgaat atgaagtaac agaagacgga caaatcgcag tgacgctact
    28621 tcgcagtgtg ggagaactag gcgattgggg atattttcca acaccagaag cacagtgtct
    28681 aggtgagcat cggttcaatt acagcattga actacatgga ccagaagaaa aattctctac
    28741 ttatttgcat gcatacgcag cacagattcc tttttccact caacaaatca aacatcatga
    28801 aggaacattg atttcaaaac aacaatattt aacgataaaa agtgaaacgt ttgcaattac
    28861 agctttgaaa cgcagcaagt ttagtgataa agtagtagta agaggtttca atatgtctag
    28921 tcatttagaa aaattggaaa taactaaaga caatggaaaa actgtcatat tgaatctgct
    28981 tgaagaacca acgaagcaag cggttgtccc aataatccaa ccttatgaga ttcggacaat
    29041 cggattcgag gaggaaaacg aatgtatggc ggaatagaag caggcggaac aaaatttgtg
    29101 tgtgcggttt cagatggtgg agaaatttta gaaaaattaa gtatccctac cacaacacca
    29161 gaagaaacat tggatcaggt atttgaattt tttgatcgtt atgaattgaa gggaatcggg
    29221 attggctcat tcggcccgat tggtatcgac aaaacaaaag ataattacgg atacgttttg
    29281 gcaactccca aaaaagggtg ggcacaattc gattttcttg gcacaatcaa ggaacgctac
    29341 aatattcctg ctgcttggac aacggatgtc aatgctgctg catatgggga attgaagcaa
    29401 ggagcagcac aaggaaaaaa tagttgtatt taccttaccg tgggaacagg aatcggtgca
    29461 ggtgtcgtga tcaatgaaga aattttttca gggatcgcac atcctgaaat gggacatatt
    29521 tgggtgaaac gccatccaga tgaccattat gaaggtactt gtccttatca taaagattgt
    29581 ttagaaggat tagcagcagg accgtctatt gaggcacgca cagggatcaa agggcaagat
    29641 ctgccgcaag atcatcctgt ttgggctatt caggcttatt atattgctca agcactgatc
    29701 aactatacgt tgacgttagc acctgaaaag attattttag gcggtggggt aatgaatcag
    29761 gatcatctcc ttcaaaaaat ccgtcagcaa tttgttgaat tgatgggtgg ttatatggaa
    29821 acacctcaag taagtgaata tatcgttcgt tggggactgc cgaatgaaag tgggattatc
    29881 ggtagtttgc tgttagcaga acacgaacat caaaagtaag cagacaaatt acacaaaaag
    29941 aacagagtct tatcattatc tgctgataag actctgttct tttttatttc tattcccata
    30001 atccaggtaa agctttaccg actatttttt cttgagtaaa tggatggatc atgtgcagtt
    30061 ctaatgcatg gagcatcagt cgttcagctg ttctattttg gtagagaggg tctccaacga
    30121 tcggatgtcc cttatgagct aaatgaactc tgatctggtg tgtacgtccg gtttccaaaa
    30181 cacaatagac ttgtgtttgt tcagaaagta ctttgttgac agtgacatgt gtcaaggcgc
    30241 tctgaccatt tttatcatct acgacccttt ttctccgatc atggcgatct cgtccaattt
    30301 tattggtgat ggtcatatct ttggcaattt ctccccatac gatggcttga tatctccgat
    30361 agatcatttt ttgttccaac attcttccaa gtatcggcaa gacaaatgga ttttttgcaa
    30421 ataaaacggc accgcttgtt tctttgtcca agcggtggac aacgtaaggt cgttgctgtt
    30481 tagtgtcgag ataagcagct aaatgattga gtaaggtact gttttctgtc ggttcatttg
    30541 gatgagtctt cattcctgca ggcttatcca ctataatcaa atgctcatct tcatataaaa
    30601 cacggatgtg cttcgcatct cctaattgaa cttcttgata attataatct gtttcttcga
    30661 ataacaatgt gatctggtca ttgcccttta cttcatgatg gaacaaagca ggttgttgat
    30721 tgatccaaac gtttttacgt atacgcaaaa agtgtcgaac ctttctagga actaaccatt
    30781 ccttttcaag caagtcgcga attgttgttt caggatggtt cataggtaaa gtgatcgtga
    30841 ttttcacaag tgtactcctt tcagtgcaat tgcagactaa ttgtaccatt tttaaaacat
    30901 atttaagaaa aaacttacat ttttctgttc attcttatgt tactctactt gcactaacgt
    30961 aaaaaaacat attgaactac aacttaagca ggaagaaaac actctttcac tatggtaaaa
    31021 taagacgatt gaatcaaata gacaggagaa gaagcaaatg gattttcaaa gcattttaga
    31081 aaagataaaa gctgctttga tcagtttttg gcgttggatc agaccatatc tcggacaatt
    31141 ccatcgatgg cgaaagcgca tctggaaaaa atatcatgtg aacaaattga ttttgctgat
    31201 tggtttgatc tgtgtcttag tgacaagtat ctacctcttt attttagcaa aacaagcaaa
    31261 tgtcgaaacg ttaaaatcag gattaagcca atcgacagtc atttatgata agaaaaacga
    31321 agaagctggc acactgtacg cccaaaaagg aacatatgta gaattaaacg cgatttctcc
    31381 ctatatccaa gatgcagtaa tctcgacaga agataggaat ttttacgagc atcacgggtt
    31441 tgatatcaaa gggattgccc gtgcagcagt ccgaatggtc ttgtctggcg gaacatcagg
    31501 gggcggagga agtacgatca ctcagcagct tgccaaaaat gcgtatctga cattagacca
    31561 aacgtttgat cgaaaagcga aggaattatt tttggcaatc gagatcgaaa agaagtacag
    31621 caaagaagaa atcttgacca tgtatcttaa caatgcctat tttggcaacg gggtatgggg
    31681 tgtccaagac gcttccagaa agtattttgg agtagatgca acgaatgtta cgctgtctga
    31741 ggctgctact ttggcaggaa tgctgaaagg tcctggtatt tataatccga tcgatcaccc
    31801 aaaaaatgcg aatgatcgga aaaacacagt actaagtgta atggaagaaa acggaaaaat
    31861 cacaaaagaa caagaacaag cagaaagcca gacagatatc agcgcgtatc ttaatgacac
    31921 atacgataat tcagattctg gttatcgtta tccttattat tttgatgcag tgatcgatga
    31981 agcagttaac gagtatggtc ttgatgaaga agatgtcatg aataaaggct ataaaatcta
    32041 tacagcttta gatcaggatt atcaaaagca attagaagct acttatcaaa acagtgcatt
    32101 attcccagca aatgcttcag atggtgccat ggtccaatct gcttcagtag ctttagatcc
    32161 gaatacaggt ggtgtacaag cactagtagg acgaagagga gatcatgtct ttagaggatt
    32221 cagctttgct acacagatgc gtcgttcacc aggatcaacg atcaaaccat taagcgtata
    32281 tacaccagca ctggaagctg gatacaagcc ttccagtatc ttgaaagacg aaccgcaaag
    32341 ttattacgat gcgcataatt ttgacgggac ataccaagga gaagtaccga tgtatcaagc
    32401 tgttgcacaa agtttgaatt tgcctgctgt atggcttttg catgagatcg gtttacaaaa
    32461 aggatatgat aaagcagaag aattcggcct gcctttagca aaatctgata agtattatgg
    32521 cttagccctt ggtggactgg aaaaaggagt atctccattg atcatggcgg gtgcttacag
    32581 tgcatttgcc aatgatggtc agatgtatac gccgcatctt atcacgaaaa tcgttgattc
    32641 gactggagcg gtgatcgtcg ataacacaaa caaaaaacca aaacaggtca tatcaaagga
    32701 aacagccgat gaaatgacca gcatgcttct tggtacattt tcaaatggaa cagcggctgc
    32761 tgcgaatcct gcaggttata cgatagcagg gaaaacagga accacagaaa ctaatttcga
    32821 tgccacaaaa gcaaatgacc aatggatgat cggttacacg ccagacgtag tgatttcgac
    32881 atggatgggt tacgaagaat ccagcaagct gcactatttg gaagggacaa gtggaaatgt
    32941 tgtcgggaaa gtcttcaaat cagcggcaga aggcatcctt ccgtatactt caaaaacagg
    33001 atttagtgta gcagatgcct atgccacagg aggacaagtg gtagctgcag atcaagttgg
    33061 aaacacagga aattctaatg gagagtctgg aaattggcaa gataacttga atcaatatgg
    33121 tgaacaagca aaagaagggc tgaaaaactt cggcgatatg gtgaaagaag gcgttcaggg
    33181 aattggtgaa gcggctaaag acctctggcg gaaatatcaa ggagagtagc ccctttgaaa
    33241 acgaataacc ccatgttaca atagagagta actactaaaa gaaaagaggg cataacatgt
    33301 caaacatcta cgatagcgcg aatcaaatcg aacgtgagat ccgtgaatta ccagaattca
    33361 aagcgttgaa agaagcgtac gagaaagtac aagcaaacga agaagcacac aaactgttca
    33421 aagacttcca agcgatgcaa atcgaattac aagaaaaaca aatgagtgga caagagttca
    33481 gcgacgaaga tgcaatgaaa gcacaagaaa tggctgtgaa aatccaatca gaagaagtaa
    33541 tcaatgactt gatgcaaaaa gagcaaggct tcagtacaat catcaatgac ttgaaccgta
    33601 tcatcatgac accagttcgc gacctttaca gcgaataaaa ctattttatg aaacaacaga
    33661 gggtgtgaaa gagacgttcg gccttgagcg atgacaaaat tgcttcttat tgccgatagg
    33721 ctgtctcttg aacaccattt accaagaggt cgtgagccta ccgtttaact ctgagttaca
    33781 aggaacaatt tcaaaaaaca gcttctcatg tttgatgact attgtgactt gtgaccgagg
    33841 agttggcagg agaacaccgt ttattcagaa ataggagcta cgacaaaagt cttgtcatag
    33901 ctcctatttt ttgtcattca tttttcaagc ggtagaaata gcctttttga gctaacagtt
    33961 tttcgtaagt acctatttca acgatttttc cttcatcgat cacaacgatt ttatctgcct
    34021 ctttgatcgt tgaaagccga tgagccacaa taaaagtagt gggtgtttct gtcaggtaat
    34081 tcagggcttg ctggattttt ttctctgact ggttatctaa agctgaggtt gcttcatcta
    34141 gcaaaatgat ttttggctga cgtatcaacg ctcgtgcaat ggagatacat tgcttttggc
    34201 caccagacag cttgttgcca tgttcgccta ctaaggtatc cagaccatca ggaagctggt
    34261 caatcagtga agaaagttgc gcagcttcga tgacttcatc taaacgttct tttgatacgt
    34321 ttttcaagcc ataagtgatg ttctctttga tcgaagcgga gaacaacaaa gtggtttgag
    34381 gaacaacggc taaataattt cgcacacttc gcatatccag ttcatccaaa ggctgatcat
    34441 ctagaaaaat ttttcctgaa gtcggctgga taaatccaat caataagtta aggagtgtag
    34501 attttccaga gccagatggc ccaacaaaag caattgtttc tccagctttc acctctagag
    34561 aaaaatgatc gataatcggt ttgagtgagt ccggataaag aaaagaaaca tcctcaaaac
    34621 gaaaatttcc atccaaatgt tggatttttt tcttaccgtg ataagtttct acatcgccag
    34681 caatcaacag ttcgccaata gaagtgatag attccatgcc ttttgaaatc gtaggaatca
    34741 gcgtgatcat tccagaaacg gaattgacga tcgtcgtgaa atacgtctga tacatcacga
    34801 catcgccggg ttggatgcgc ccttgtaaag ctaatatccc agtgaaactc aaacaaatca
    34861 gctgaaatat ctgaaaacta gcccagctga ctgatccgaa aacagattgc aggatatcta
    34921 agtggaatcc tttttcatag atttgagtaa aatgcttatt taagcgagtt gtttcgtgtt
    34981 tttctaaccc atgagctcga gcaatcggtg ctaattcgat cacttcgatc acttttgcag
    35041 aagtctcttc catttcttgc ctgaagtctg agttggactg tctgatcctt ttacggaaaa
    35101 agagagtaac gaatgcggcg agaggaacag tcaataagaa aaacatgaaa acaacaggac
    35161 ttttataaag cgtgatacct aaagctacga ataaattgac agcgatattt aatccgctga
    35221 caaatacttg agaggacaac gtttggatag cttctacatc acggatgatc tttgactgga
    35281 ttcgtccaga ttgcaattct ttttgataag gaatagatag ttcttggatt ttcttgataa
    35341 gggtcgctct tagtccagct tctacttgac ggatcgaagt gctatggtat tttacatgaa
    35401 aataattcgt caatatattt tgaccaatca gacaagccat caaaaaagcg ttgaaataaa
    35461 tggcctgcaa ctgagaagaa tctttcgatg aagctgcatt gattacattg gcaatagcga
    35521 tcggcattaa ccaagatgga agatgtttga taataaaaaa gagtcctgac atggcaaaac
    35581 gccaataatt tccctgataa agatgcagca atgtctgaaa agcatttgca tgatattttt
    35641 gataactttt ctgtattcgt tcctccataa tcttctcctt aacaatcttg gtaaataaac
    35701 tgcaagtgtt ctattgcttc aggaacataa atctcaggag tagcttcaag agtggcgtac
    35761 attagaggac gctcatattt gatataatgc agtaccgggc ggaaatctaa acagcccttg
    35821 ccaacaggta ccatgcggat ctttccattt tccatgatat agtctttgag atgaagcgct
    35881 gtaatataac catgtaaatt gtccaaggca cctcggatca ctttttcctg atcagcatga
    35941 ttttctttat gcatcaaatt cgcacaatct aaaatgattt ttaaatttgg tgaagctact
    36001 tcatcgatta aacgtttagc taactgatag ttatagattg gatgattgat ccctgcttca
    36061 acagcaacag ttacgccaaa attttctgca tgagcgacta attcaatgat agaatttctg
    36121 gcgatctgat aagcttcttc agtaaaattt tcttttgtgt aaccgacaga gacactaccg
    36181 gtttccgtag caatcatctt ggcttgatag gcagagcaca gagcaatttg ctgtttgaaa
    36241 gttgccaatg cttgtgcacg aacttcttga tttttgctgg ataggttgat atagcatcct
    36301 aaaatggaaa gttcgatatt gtttttttgg aagtattcac caaaataggc agcactccca
    36361 agtgtcatgt cagttaattt aagttgttca ggaaatgctt tttgtggtgc aaattggata
    36421 tgggacaagt gaagctgtga tactttttga acgatttctt cacgatttcg aacatctaaa
    36481 tcgtgggcac ggatgcctaa atttaatgga aacatctcaa actccttttt gtaaataatt
    36541 agcaagaggc agacgggatt cttttatcaa ttcaacaatt attcgggcaa ctttatcagc
    36601 gccttctgga ctaaagtggg tattgtcttt tagtccttct gggtaatttt tacaagtatc
    36661 aggcataaga tgcaggtaga atttttttgt ctcttctttt gagaaggtct ggaacaattc
    36721 ttgtgatctt gagaacacat ctaaaagagg aatatggtgt ttctcagcaa atgcacgcat
    36781 cgcttttgga tagtctccaa gtatatctgg attcaatgtt ccgttttcta agtaatctcg
    36841 tcgcgtcaca gatgtcagta agaccatttg gacgttcgct ttttttgcgc attcaaaaaa
    36901 tatctgcaga ttttttaaat agctaccgaa gggaagcgta cctctttctt cttggatttt
    36961 ctggtcgtta tgtccaaatt gtacaaataa gaaatcattc ggctgaaact gtgaagctag
    37021 acgggctaac cttccttcct ggataaatga tttggtgctg cgtccattct ttgcttggtt
    37081 attgatctgg atctcgggtg aaaaataagc agagattttt tctccccaac ctgtctcggg
    37141 acgcttgttt tcatcttttt ctgccgcagt agaatcaccg gcaatatgga tagtaggcat
    37201 gttatctctt ctttcataaa ggtttatagg caatgaagca gaacagcaag agaagaagac
    37261 ggagcaa
//
LOCUS       DAZUJR010000018        36503 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.018, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000018 DAZUJR010000000
VERSION     DAZUJR010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36503
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.018"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            305..625
                     /locus_tag="ACG804_000849"
     CDS             305..625
                     /locus_tag="ACG804_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HFS4831797.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            779..1684
                     /locus_tag="ACG804_000850"
     CDS             779..1684
                     /locus_tag="ACG804_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4831798.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            1681..2454
                     /locus_tag="ACG804_000851"
     CDS             1681..2454
                     /locus_tag="ACG804_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFS4831799.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(2635..4059)
                     /locus_tag="ACG804_000852"
     CDS             complement(2635..4059)
                     /locus_tag="ACG804_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="basic amino acid/polyamine antiporter"
                     /protein_id="HFS4831800.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            4270..4716
                     /gene="nrdI"
                     /locus_tag="ACG804_000853"
     CDS             4270..4716
                     /gene="nrdI"
                     /locus_tag="ACG804_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HFS4831801.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(4781..6763)
                     /locus_tag="ACG804_000854"
     CDS             complement(4781..6763)
                     /locus_tag="ACG804_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose PTS transporter subunit IIA"
                     /protein_id="HFS4831802.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(6777..7673)
                     /gene="murQ"
                     /locus_tag="ACG804_000855"
     CDS             complement(6777..7673)
                     /gene="murQ"
                     /locus_tag="ACG804_000855"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HFS4831803.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(7676..8737)
                     /locus_tag="ACG804_000856"
     CDS             complement(7676..8737)
                     /locus_tag="ACG804_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HFS4831804.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(8948..9475)
                     /locus_tag="ACG804_000857"
     CDS             complement(8948..9475)
                     /locus_tag="ACG804_000857"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFS4831805.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            complement(9542..11044)
                     /gene="eat(A)"
                     /locus_tag="ACG804_000858"
     CDS             complement(9542..11044)
                     /gene="eat(A)"
                     /locus_tag="ACG804_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HFS4831806.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(11302..12423)
                     /locus_tag="ACG804_000859"
     CDS             complement(11302..12423)
                     /locus_tag="ACG804_000859"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFS4831807.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            12549..13490
                     /locus_tag="ACG804_000860"
     CDS             12549..13490
                     /locus_tag="ACG804_000860"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HFS4831808.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(13640..14536)
                     /locus_tag="ACG804_000861"
     CDS             complement(13640..14536)
                     /locus_tag="ACG804_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HFS4831809.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            14805..16145
                     /locus_tag="ACG804_000862"
     CDS             14805..16145
                     /locus_tag="ACG804_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFS4831810.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            16363..16806
                     /locus_tag="ACG804_000863"
     CDS             16363..16806
                     /locus_tag="ACG804_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HFS4831811.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(17310..18728)
                     /gene="nhaC"
                     /locus_tag="ACG804_000864"
     CDS             complement(17310..18728)
                     /gene="nhaC"
                     /locus_tag="ACG804_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HFS4831812.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(19131..20354)
                     /locus_tag="ACG804_000865"
     CDS             complement(19131..20354)
                     /locus_tag="ACG804_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFS4831813.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(20385..21224)
                     /locus_tag="ACG804_000866"
     CDS             complement(20385..21224)
                     /locus_tag="ACG804_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFS4831814.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(21241..21921)
                     /locus_tag="ACG804_000867"
     CDS             complement(21241..21921)
                     /locus_tag="ACG804_000867"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HFS4831815.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(21923..22996)
                     /locus_tag="ACG804_000868"
     CDS             complement(21923..22996)
                     /locus_tag="ACG804_000868"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HFS4831816.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(23052..23290)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(23333..23566)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(23643..24314)
                     /locus_tag="ACG804_000869"
     CDS             complement(23643..24314)
                     /locus_tag="ACG804_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFS4831817.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(24401..27049)
                     /gene="mgtA"
                     /locus_tag="ACG804_000870"
     CDS             complement(24401..27049)
                     /gene="mgtA"
                     /locus_tag="ACG804_000870"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015444 - P-type magnesium transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HFS4831818.1"
                     /translation="MEKKKDTQKIYAAFAGKTKQELFELFHASANGLTEEQIERSREN
                     YGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPGDKDLFGVAII
                     FTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEEIVCGDLVRLS
                     AGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSYENLVFMGSNV
                     ISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKFMSLMAPAVIV
                     INGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGTVIKNLNAIQN
                     FGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQTGLKNLLDVAI
                     IDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGAIEEMLNISKF
                     IDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFSVKDESDMVLI
                     GYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLEINELVTGEKI
                     SEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGINDAPAMKVADI
                     GISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKATASSNFGNMFS
                     VLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKWNASSIGEFMV
                     YFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAGWFVESLWTQT
                     LVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLMPLPGNYWLWL
                     FATVIAYLALVTAVKKIYIRRFQELL"
     regulatory      complement(27391..27565)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            27738..28175
                     /gene="ndk"
                     /locus_tag="ACG804_000871"
     CDS             27738..28175
                     /gene="ndk"
                     /locus_tag="ACG804_000871"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HFS4831819.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(28197..29063)
                     /locus_tag="ACG804_000872"
     CDS             complement(28197..29063)
                     /locus_tag="ACG804_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFS4831820.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(29223..31316)
                     /locus_tag="ACG804_000873"
     CDS             complement(29223..31316)
                     /locus_tag="ACG804_000873"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFS4831821.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(32065..32688)
                     /locus_tag="ACG804_000874"
     CDS             complement(32065..32688)
                     /locus_tag="ACG804_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831822.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(32847..34244)
                     /locus_tag="ACG804_000875"
     CDS             complement(32847..34244)
                     /locus_tag="ACG804_000875"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFS4831823.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(34276..35247)
                     /locus_tag="ACG804_000876"
     CDS             complement(34276..35247)
                     /locus_tag="ACG804_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4831824.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            35621..36046
                     /locus_tag="ACG804_000877"
     CDS             35621..36046
                     /locus_tag="ACG804_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831825.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
BASE COUNT        10566 a         7606 c         6395 g        11936 t
ORIGIN      
        1 ccgataatat atagaaataa ggtctagtta ctgttttttt taaatgatta ataaataaca
       61 acttctttct atgaaattgc aaagcattca tcttcttttc cgctaacgat atatccgtca
      121 gtgcttggta cactttacta aaaagtatga gattgccgat atctggatag gtgtgctata
      181 ctacagaaaa agatatacaa tctgccaccg ggtaggataa agaggatgat cattccatta
      241 ggtctttgaa gggatgattt tcctcttttt gtgtattttt ttatagttaa ggaggaatgt
      301 aagtatggca tggatggaat taatcatagc aggaattttg gaagtattct ggtcaacgat
      361 gatgaaatgg agtgatggtt tttctaaaat caattattct ttttacacag tgattggcat
      421 gattgctagt ttttactttt tgtcaaaggc aatcaaaagt ttgccgatga gtctctctta
      481 tcctatctgg acagggattg gcgcagttgg ttcggtcata attggtgtgg tcttgtttca
      541 tgataagctg aatctttcca cttggttctt tgtggggatg ctactcatca gtatcattgg
      601 catcaagatt actagcggcc actagacact tggaataagt actgatcaga aaaaataagc
      661 ctttttattt aatattcaat ttttttatga aaaaataaga aataagtcca atgacctagc
      721 gacttctcca ctcatcaggt gtatgcttgt actatctata gaaaaggagt gaatattttt
      781 gaaaagtctt tcggtccaag aattatccaa gaactttggt cacaaacaag ccctcagcga
      841 tgtcagtttt agcttatccc ctggcaaaat cgttggatta gtaggtccta atggcgctgg
      901 aaaaacaacg atcatgaaag ctattttagg actgatccat tactcagatg gaacaatctg
      961 tattggtgaa aatgagattt ctccctctag tcataaaggg ttggaacaag taggagcatt
     1021 gatcgaatac ccgggtatct atccattctt aacaggctat gatcatctga agttattctc
     1081 tgaaaccaac gatgtatctg ctatcgacac tatcgtgaat cagctcaaga tggaaaagta
     1141 cattcacaaa aaagcgaaat cctactcgtt gggaatgaaa caaaaattgg gaattgctct
     1201 tgccttactg aaccatccgt ctatcgttat tttagatgag ccgatgaacg gtttggatcc
     1261 acaagcaaca agagatgtgc gaaaaatcat taccgacttg gctactcagg gcacctcttt
     1321 cttgatctcc agtcacttac tcagcgagct tgaaaaaatg gtcgatgagc tgatcctgat
     1381 caatcaagga aagatcatca aacaatgtac aatggctgaa ttgaaccaaa cagcgcaaga
     1441 tttcatcgtt atctctacaa caaatgatct agctgctcga acgatcttga cagaagctgg
     1501 atatactttg gaagatcctg ataaaatcaa gcttttaaaa gaaaacgaag aattattagg
     1561 aaccgtgatc cagctattgt ctgcacaaaa tatccatgtg acagacgtcc agcatctgac
     1621 gaatgatttg gaatcttctc tattggaaat tctggattca gtaaaggggg aagaagaaaa
     1681 atgacattgc ttgtaaaaca agaattattt aaattgatca agaaaaagtc aactgctgtt
     1741 ttatctgttc tattagttgt tttgctcata ggaacagcac ttctagccaa aaaatacacg
     1801 acgatcattg atccagttga aatgactgct cagcttttta gtgccacatc ttggattgtc
     1861 tttatcatga ttgcagctgc aagcacgatc atttcgatgg aagcacaata tggtacattg
     1921 aaaaatctcc tttatcgaaa gtattctcga ggagaaatat tagtaagcaa atggatcaca
     1981 ttagttattt attctgttta tttatacctt ttagctatta ttgtcactgt gttgatgaaa
     2041 ctgattcttt tcccttcgat ttccttcacg gagaaggttt ctactggtca aacactgatc
     2101 caaagcttgt tcacttatac tttgggtagt tatatcggtt tatggctgat tttaagttta
     2161 gtgttgatga ttgcttgctt tatcaatagt tccggcgcat ccatctcagc aggaatcgtc
     2221 ttttattttg cttcgtcaat catatctggt atccttattg cactcatcca aaaatgggag
     2281 tggatcaaat ggaatccgat cagtatgttg aatctgcaaa accaaattgg aaacgaagag
     2341 atcatgaagc aattgactca tctttctact aatcaaatgc tattcggtaa tttagcttac
     2401 atcgttttgt tcttagcatt aggatatctc gtatttaagc gaaaaaatgt atgatgactc
     2461 atcaaaaaag aggctgtgaa agagacgttc agccttattg ccgattggct gtctcttaaa
     2521 caccgtttat tctgaaaaag gagctgtgac aacatttgtg tcacagctcc tttcctagta
     2581 tgtttttgaa taaacgacag gctcacaacc tctctttata cttcttttat acttctatac
     2641 gtgaagcatc ccagtggcaa ataaaaccat tgcaatcact ccgaccatcg tcacacctat
     2701 aagtaaaatc ttatctaagt ggatatgttg tacaggctcg ttttgctcct tacgtgcttt
     2761 gaggtaaaaa taaatgcctg gcaagaaaag aacaagaaca agcattactt cattaaaggc
     2821 tacgactagc atagcccata cttgaaaggc acttgctaaa agccctacta aaaattggac
     2881 ccattctttc cgctgataag aaagtttcat ttggtacaat cctaagaaaa gccacgtgaa
     2941 gaaaatagct gctgtaccaa gtgtgtaagc aaagttataa gcactgtcag tgaataataa
     3001 tgaaagtaaa aagacattcg tacataacgt cgtcaatacg atagcataag ttggtgcccc
     3061 atttttgttg agttttcccc atgctttagg caaaagtccg tcttcagcca tgtttcccat
     3121 tgtttcaatc ggtaagatcg tccatgagag ccaaacacca actaaagaaa tgatcaaacc
     3181 gccgttgatc acgactgctc cccatttacc aaccatcatt tcaaacacat agcccatagc
     3241 aggctgcgcc ttgatcgttt gcagctgatt catcgtcatt gtcccatatg gaagcatgga
     3301 aaccaagacg taaataataa tcaagccgaa tatccctaga atcgttgctt tcccaacatc
     3361 tgattgtttt tttgctcgtg aacctacgac agaggctcct tcaataccaa caaataccca
     3421 aagcatcacc atgatgcaac tcaatacttg actggaaaac gggatcggct gtccattcgc
     3481 attcaatata atgtcgctag aaaagttatc aatgaattgt tggatcgaaa acgtgctgat
     3541 agctactaca ataaataaaa ataatggcac taatttacag aatgtgacga tagcattgac
     3601 gaaactagca ttttcgactc cccgattcac tagccatgca tatccccata aaaagactgt
     3661 actcatcacg atcgatgcca gattttgccc accttcaaat actgggaaga aatatcctaa
     3721 tgcgctcatc aacaatgttg caaaagctac gttgcctaac cagcatgtga gccagtaacc
     3781 ccaaccgctg ataaaaccag cgaaacggcc aaaaccttct tctgcgtaac taaagatccc
     3841 gccttttaaa tctggacgtt ttttattgat attattgatc gacaaggaga gcatcaacat
     3901 tgctgttcct acgagtaccc aactgaaaat agctgggccg ccagccgatc cggagatgtc
     3961 cgtcataata ccaaatacgc cacctccaat cgctgaacca attactaagg cagcaagtgg
     4021 aattaaacca attccttttt tctgttgctc tgtatccatg taagcatcct ccaaaataaa
     4081 accgctttta tcaaaaagta taacaaacct tttttatttt tacttaatta ataaaaactt
     4141 taatagaaat ataattctac cggctttttt ctcattatac aagcaaagcg cctagtccct
     4201 ttccaaatta caccaccaaa aaacttaaaa aagatgctat actaaaagga aagaattgga
     4261 ggatgatcca tgaacatttt atatatatcg atttcaggaa atacgcgtgc ctttgccaaa
     4321 catctagcag aatatgctga aaaaatgcat gcagaagatc ctgtcaatcc tgaagttact
     4381 ttaaaagaaa tccatgaaaa tagtgatttt acgaaagaaa cagaaccatt ttttactttc
     4441 gttcctactt atttagacgg cggaaatggt ttagataacg gtgatacaga aatcttgacc
     4501 gaaacgatgc gtgaatatct ggaacatgaa gacaatcata aactttgtct tggtgtagtc
     4561 ggtagcggaa ataaaaactt caataatcag tattgtctaa cagccaaaca atatgcacaa
     4621 acatttggct ttcctttctt ggcagattat gaattacggg gaacaccatc tgatgtgaca
     4681 cgaatttatc agattttagc agaaaacaat aaataataaa aaagaagaag ctgaaaaata
     4741 gatttcagtt tcttctttcg tttctattgt ttctatcata ttaagctttg acatccatca
     4801 caggtgcttt tgcttttgct ttacctgttt tttccaagac aaagtttttt acacgatcca
     4861 tattggttac caagacgatc atggatgttt ctttgcctgc tgctttgatc gcttctaagt
     4921 cagcttctgc tacaagcgta tcaggtgtca cttgctgccc ttctgttact ttcacatcaa
     4981 atggcgtacc gcctaagtca actgtgttga ttcccatatg aagcaagatt tctaaaccat
     5041 ttggcgttgt gatcccaata gcgtgtttcg ttgggaagac agagctgact accccagtaa
     5101 ctggagaata gatatgtccg ttttctggtt ctacaaagta gccttcaccc atcatctttt
     5161 gtgcaaaaac tggatcactt gctttatcta aagaaacaac tgttccgtca gcaactgatg
     5221 agaggatagt cacactttca gctgaagttt gaggtactac tttttcaggc acttcattta
     5281 ctgtggctgt ttcagtcgct aattcttctt tttctaaacg gtctttagga ataccgaaga
     5341 agaatgtagc aacgaagcca ccagcataag ctgccaataa tccaaggatg tagcctaacc
     5401 atttaccgtc agagatcaat gggatcaaag cggctcctga aggtccaata gcgatagccc
     5461 cgacatttcc gatcattccg atcactgccc cgccgatacc tccaccgata caagcagtaa
     5521 taaatgggcg tcctagaggt aatgttactc cgtaaatcaa tggttcgccg attcctagga
     5581 tcccgactgg taaagctcct ttgatcattt ctgttaattc tttatctttt ttgcagcgaa
     5641 tccataatgc caatgctgca cccacttgtc ctgcaccagc catcgcaaga attggaagca
     5701 atagcgtacg accagtttca tcaatcattt gcacatggat tggagtcaaa atttgatgca
     5761 gtccgaacat aaccatcggc aagaataatg tgcctagaac gaagccggca aatgctccac
     5821 caacgccaag tacccagttg atcccaccga ccatgccatc agaaatgaaa cctgctaaag
     5881 gcatgatgaa gaaaatttca atcagaccga tggcaatcaa tgaaagagtt ggtgtaacga
     5941 tgatatctac cgcatcaggt actactttat gcagtttttt ctcaacgatt gacaatagcc
     6001 aaacagcgaa gatgacacct aggatcccac cttgtccagc tgcaagagct tcaccagtaa
     6061 ataagttttt cagtggtgct tccggattca tccctgtcag catcacaacg gccccgataa
     6121 ctccaccaag agttggtgtt gcaccaaaaa cttgtgcagc attgatacct gtatagataa
     6181 ctaggtagct aaacatcccg tttttcaaga tgttcatcac atcgatatat tgttgccatg
     6241 ttgctgcatc aagtgttccg gctgtgacta agtttgctaa aactgcggca atccctgcca
     6301 cgatcccagt accgacaaat gcaggaatca ttggcacaaa gatattagaa atgtctttta
     6361 ataccgattt gattttagat ggtttttgtt tcgatttttg tgccgctttc atttcttgtg
     6421 cccgttcgtt tacacggtct tttccagatg ctgatgaatt tgctgtagct gtacttacag
     6481 aagaaagttt ttctcctaat ttcacgcctg ccaaatcaac catttgctgt gctactttgt
     6541 tcactttccc aggtccgatg atgacttgaa gctgttcatc ttctactaca ccaagcactc
     6601 ctggaatcgc ttttaattca gagacattta caagatcatc attgatgatc ttcatacgca
     6661 cacgagtcat gcagtggaca atgctttcta cattgcccat gccgcctgcc cctttataaa
     6721 tttgttttgc cagttcttcc aaagtcagtt cgttttttgc catggtcttt tccccctcat
     6781 aaggtccctt ttacaaatcc gtttgcttca gctaattttg cttgagcttc ctctttatca
     6841 ctatttgtca aaatcatgac gatagccagc ttaacatttt gatctgcttc ttcaaagtac
     6901 ttttcagctg tttcgtaatc agcttctgtc gcttgcatga tgattcgttt tgagcgttcg
     6961 attagttttt catttgttgg tttgacatcg accatcaagt tattgaatac tttacctata
     7021 ccaatcatac tgatagtaga aatcatattc aagataagtt tttgtgctgt tcctgacttc
     7081 aatcgagtag agcctgtcaa aaattctgga cctgcatcga cttcgattgg gaaatccgcg
     7141 tgtttactga tttcggcttg tttattgcaa gaaatcgttc ctgtgacagc accgatcgat
     7201 tttgcgtaat ctaatccacc gatcacatat ggtgtacgac cgctagctgc gataccaata
     7261 actatatcat tttttgtcaa attcagcttg attagatctt cttgccctag ctcataagaa
     7321 tcttcggccc cttcgacagc tacagtcatt gcttcttctc caccagcaat tagacctatg
     7381 accatttccg gttctacacc gaatgtcggt acgcattcag cagcatctaa cacacctagt
     7441 cttccacttg ttccggctcc catataaatc agacgtccac cttttttaaa ggactcaatc
     7501 gtgttagcaa tcactggttc gatacttgtc agttcttttt caaccgcagc ggccactttc
     7561 tgatcttctt tgttcattag ttgaacggct tgagaaatac tcatctcatc taatccaaaa
     7621 gtttcttggt ttctgcgttc cgttgttagg ttctctaaat tgattttgct catttttatc
     7681 ttccttcttt tcttataaat tgatagttca taccagcttt gatttggttg atcaatggta
     7741 gctcttcttt gataacttta gctactacat tcactttttc atccgctggc aaatcatatt
     7801 tggttaattg gatctcaccc atatagcgca aatacttttc gttatctaaa gtaatagacc
     7861 ctttcatacg cgtagctgta tttcttgctg ggataggcgg aatctctcga aaacgtgcat
     7921 ctacgcttcg tatgacatct cttgcatcgt cttgccgatt cgtatgcttc cctaatatat
     7981 attcgtaaaa ttcttcatct acaggttccg tatggagcaa gactgtctgt tctttttgga
     8041 aagaagcaaa ttgctcctga acgttttctg acagacctgc atctccgatg taaacaatat
     8101 ccgtgttact tgctaataga tctagagcgc ctgcaagagg atggatccct cgatgttctt
     8161 ccaaagttgg caatccttga tatagtgggc ctctcaactc tgtatctcct ggtacaaaac
     8221 cttggacaag gagaccttga attttgagcc attgattttt tttctgatac cattctttgt
     8281 ccagccctgt ttcgggacgt ggataataat tatgccaagc ttcaatctgt gagaaatcag
     8341 cttctgcttc tttcaattca tcgatatctt taggcgtgat cgtgctagca ttcaaactga
     8401 ttttcaattg atgtgaccag tcggcaatct gctgattgga aatatgataa tccattctta
     8461 aacctgttac accaattgct ttcaaaggcg ttagatcttc taatgaaaaa cccgctcgtt
     8521 ccaatgcctc tcctgaaata tcgaccatca attctagttt attctttttc gcttcgcttc
     8581 ctagttcgat caatcgcttt tgatatgccg aaacatcatc ttctggtata tgcatggaag
     8641 tgaaaatacc gacaaagcca ttggatgcca tttggcggat atactgtttc ttctcttctg
     8701 acaaagaatc gttcataaat attgaaaagc caaacatatt atccctcttt ttctgtatcc
     8761 gtcttcattt ctatgactag agtatatatc taaagaaaca aaatttcaat acttttatta
     8821 aaataattaa atttcatttc taaaggttga gtttatatta tcaaaagaat tgtcataacc
     8881 taaaaaaggc actgctaagc aaaagcagtg ccttgaaata ttttatttaa ataacacaaa
     8941 aacataatta ctcataagaa accaattctg tattatctac catgaatgta aagaacccct
     9001 cattaggcat cggatgaaaa taagcattga tcactcttat caaggcatta tggcaaacta
     9061 acagatagac attttcttcg tcttcgatgc attctttcaa taaaggaacg atccgtgcat
     9121 acacatctaa gactgactcc ccatttggga atcgtacagc gaacgctaaa cgtgcttttt
     9181 gaaagttctc atctttgctt ggcagtccat cataatcccc aaaatccatt tctaccaatc
     9241 gttcatcaac ggtcagcggc aagctgagac gatcagcaac tgcttgtgct gtatctcttg
     9301 ctcgttgaag aggggaatgg atgattttcg tgattggaac aggcaaatct actacctttt
     9361 ctgctagttt ctgtgcctgc atctgtcctt tttcagtcag cggcacatct gcccgtccgc
     9421 aaactaatcc ttgtgcgttc caagttgttt ctccgtgtct cgttacataa agcatgtgat
     9481 tctctccttc gttggcaaag ttccccttaa ccataccttg ttgttcttga gattacaagg
     9541 gttagattct ctcaagagaa ataatctcag tagatacttt atccaggaag gtttgatcat
     9601 gttccactag taacatggca ggtttcacgt tcaagatcag ttgttctaat tgttcttgat
     9661 tgaagacatc caaataattc aatggttcat cccatgtata tagttcagct ggctgtgata
     9721 aagatttagc caattccact tttttccgtt ggcccatact catctgctcg atcttgttat
     9781 gaaaaacatc tctttccatc ccaagctttc ggaggttgtt caaaaatgct tggtagtcta
     9841 cttggttttt ctctgcaaat tccgccaacg ttcctcgatt gtcttcataa ttttggcttg
     9901 cataactaat gctcagatgt tttggctggt atttttctcc tataaccttg ccgttgaatg
     9961 cccccagaag ataatggata atggatgact ttcctgcacc gttaggacct gaaatcgcca
    10021 cccgctgatg aggctcgatt gtaaaatgaa ttggctcgaa taacagattt tcatacccta
    10081 attgaagatc ttctacgctt aaaagtcgct tatggtgaga cgcttggcta ttcatcgtca
    10141 aagaatcgat atattcgata tcttttaata gtttttcttt ctcgctgatc tgggtctcca
    10201 tccgattcac gattgctttg gatcgtttca tcgtccgtgc agcatcagca cccactgctc
    10261 ctttattcac tcgtctagat tcagtatcga tgaatccgac ttgtttcttt gttttatctc
    10321 cttctcggga acgagaccat tcggcttttt cagctgctgt tttctttagc ctactgactt
    10381 cttttttcaa tttttcattt tgagccattt caaattcatc acgaagtttt ttctgttctt
    10441 catagataga gaaattccct tgataaagtt ccagttgact tttttcgatt gctaaaacat
    10501 ggtccactac ttcatcgata aatccccggt catggctgac cacgatgaag ccttgttttt
    10561 tctttttcaa ataagccgct acttgttttc taccagagat atccaaatga ttcgttggtt
    10621 catcgattaa cgggaaatga gtgtcatcca caaataaaag tgccagtagg acttttgtct
    10681 tctctccccc cgatagtgtg ctgaattctc tccataagat ttcaggatct gtttgcatca
    10741 attggagctc tctttcgatt tcccatatct caaaatccgt aatatcattt aacacgtaat
    10801 aggttaaacg ttctttatct tttgtctgtt gcgggaaata ggcaaattct tgctgatgga
    10861 ttacttgccc ttgataaggt agtttgtttt gtagaatatt cagtaaagtt gtctttcctc
    10921 gaccgtttcg tccgataagt cctagtttcc attgtgtgtc aaaatttaga tttgcttgtt
    10981 caaataataa tgtgccttgg ctgtcgtagc cgaatgtcag attttttatt tcgattttag
    11041 acattttcca tcacctcgta aaaaaagacc agtcctattt tcagaactgg ctaaagagga
    11101 tgcaagggtt ggatacacac aaaaagaccc atacatcgaa aaaaccaagc caatcccgaa
    11161 aatctgcaca ctgcttcctt gtctccacaa ggtacagtct gaatgcagct ttcatcaatc
    11221 gacttaattt ttcaatgcac ggatccctca ctttgtccta tatttgaaat tacgatagca
    11281 taaagaaaat gattttgtca actacttcgg gaggatggtg aaaaatctgc taagtgtctg
    11341 tcctaagatt tttgtttttt ctaatgtttg cctgtgttcc attgcttctt ctaaacctat
    11401 tggacccaaa tgaatactta agacaattgg gagaaaatca gaaagtcctt ctagctcttg
    11461 gtctctactt ccgcaaatag cgattattgg ttttcgatat ttttttgcaa gcactgctac
    11521 accgtatgga acttttccgt ggatcgtttg ctgatcgatc cgcccttctc ctgtaatgat
    11581 gacatctgct tgttcgatct ttttttccaa tccagtgatt tggctgacta aatcgaaacc
    11641 agaaaccatc ttcgctccca acaaaaaaag ggctccacca ataccgcctg ctgctccact
    11701 tcctggaata tcatctaaat ccacctccca gaaatctttt atttgctgag caatctttcc
    11761 tgcttgttta tctaagaaag ctagcgtcgt atctattcct cctttttgtc ttccaaattg
    11821 ccaagcagct ccttgttgac ctgtatatgg attggtaaca tctgcagcga taatcaattt
    11881 tactttagaa acaagaacgt ttcttcgatc aaaatgaagt tttttagtag ataataaagg
    11941 atttccttct gtgtaccctt ctaaagaagc acccaaggat tggagtaatc ctagaccacc
    12001 atcgctacac ccgcttcctc ctaaagtgac aataatttgt tctacttctt gaagcagtgc
    12061 atctttaata agttctccta aggcataact ggaagcaagt cggatagttt gatccgttgg
    12121 tttatcaagt agatctaacc ccaatgcttg tgcagattcg atgactgcgg tgttttttcc
    12181 ttgccaagtt gtcaataaat agctgatttt tcgctgacgg aataagagat ccatcccatc
    12241 aatggtacgc catgttcccc tgagcgcgta atagattgct tctgcagtat tttctccgcc
    12301 atctgcaatc ggcacattga tttttcttcc tttacgatct tcccagccat ttagaactgc
    12361 ctgatttagt tcaaatgaag aagcacttcc tttaaatgaa tcaattgccg ccaaaatatc
    12421 catctgtatc cctcactttc ttcttaagta agacactttt tttcattttt ttcaaacaaa
    12481 acaatgctat tttcttccat ttttctatat actaaaaggg aactcattga ataaaggaga
    12541 gaaaaaacat gaaaatcgca atagctgggg ccggagcaat gggcagccga atcggattga
    12601 tgctacatca aagcggaaat gaggtcctct tgatcgatcg ttggcctgct cacattgaag
    12661 ccattcgtac aaatgggttg attgctgact ttaacggtaa agaagtggtc gcaaaactgc
    12721 caatctattc accagaagaa atcatcgaaa gcaacgaaca cgtggacttg atcgtagcat
    12781 taacaaaagc caatcaatta gatgatatgt tttgttcgat ccaatccatt attactgaca
    12841 atacttatgt tttgtgttta ctaaatggat taggtcatga agatgtactg gaaaaatatg
    12901 tgccaaagaa aaatatctta tttgggatca cgatgtggac agctggtcta gctggtcccg
    12961 gaaaagtcac attgttaggt gatggagaaa tcgaactaga gaacttggaa ccagaaggcg
    13021 aagcatttac aaaaaaagtt gtagaagtct ttcaagaagc aaatttaaat ccgatctata
    13081 gccataacgt tcgttattcc atttggcgaa aagcttgtgt aaatggaaca ttgaatggtt
    13141 tatgcacgat tttggattgt aatattgctg aactaggcgc gcaaaaagcg gcagagagca
    13201 tggttcgaac aatcgtatct gaatttgctt ctatcgcagc aaaagaagga atcatactag
    13261 atcaagaaga agtgtaccaa catattgctt ctacttatga tcctgacaac atcgggttgc
    13321 attacccatc tatgtaccaa gacctgatca aaaaccatcg tttgactgaa atcgactaca
    13381 tcaatggtgc catttggcga aaaggacaaa aatatgatat tgctacacca tattgtgcct
    13441 ttttgaccca attagtccat gcaaaagaag gaatccttgg cgcagaataa aaggctctct
    13501 gatgagaatc agctgaatca gcagctggtt ctcttttttt aagcccaata aaagatcaaa
    13561 aagaaaacac aactctcatg atgccataag aattgtgctt gtttgtttca gtacataatc
    13621 tcttcaaaat gtaggttttt tatttgtttt caacagagga gaggtcatat tcgtattgct
    13681 cataaatagt ggaatcgtta gtgataaatc gttttgccca attttctgca tcataaaatt
    13741 ccaatagctc tgataggatt ggcttaaatg gtgtatgcag aaattccggt aattcatcta
    13801 aatcacgttc tcgaagcaaa aaaatatttt caggacgata aaaatgataa tgagcaatcg
    13861 cttgattatc cgtcactagt ttcttttgaa aatacatgga ttcaaatgtc cgcaaagtca
    13921 ctccttgctg accctcccgc aacagttcca gaatcccgcg cgattcccct gtttttttca
    13981 ggtactcttc ataagtaaga tatccaggtt gttcattccc tcgatgtgga agaatgaaat
    14041 agttggtcgt aacatctctt tttataaatt cctgcttata gctttctgct cgttcttttc
    14101 tcccattatt cgttgcacca aaaaatagat ccgtctttgg ttcgctagaa gaaaaattca
    14161 tatgtttcga ataaaatgaa ctattatgtt tcagcccaag ttcttttgct tccaaaaaat
    14221 caaaatgata aatctcatcg attgccggtt catcttgtgc ctgcttcagc atcgcctcgt
    14281 gttctgcttt gaagtgattc caaaaaaata acacaatttt tgcattggta aatgggcgca
    14341 cgcgtcgagc catctccata tcaaatccat aatctaaaaa aacgatcagc tgataatttg
    14401 ccaactgttg tctagctgat ttaatgaatt ccgactgtag taaatctttt ccggaccaaa
    14461 catctaaaga gcggatggaa ggcaaaaaat aaagtgattt attttttgca actagcagta
    14521 cgtcattttt gttcatcttt tccgcctcac tttctctgtc actttttcct atgatagcct
    14581 gtttaaatag taaaaagcca gtaaaacgtt tcctatattt gtatgaaaat ttaacatttg
    14641 tatgaaaata tgatgaaata aatcattctt ctattaaaat tcgcctaaaa gttttctgaa
    14701 tagttgtaat tgtctgaaaa ttttttatca ttagtcattg ttaaatattg ctatttattc
    14761 ttaatataaa ttttgattgt gaatttaaaa gaaagaggtc atttatggaa gataaaaaat
    14821 tgaaaaaaca acttagctcc agacatatca ccatgttagc tttaggtgga gcaatcggtg
    14881 caggtctatt taaaggaagt ggcgaagcga ttgggatcgc cggcccttct gtattgattg
    14941 cttttttgat tggtgggctg attttatata tcgtgatgaa aggtctggga aaaatcgttt
    15001 taagcggtgg cgacacgcat cacggattat ctggtttgat acgcccttat ctaggtgctc
    15061 attctgctga ttttactgat tgggtctact ggtctatgtg gattatcaat atcatcgctg
    15121 aagctgttgc agctgcttcc tttttgcagt tgtggttccc gcacattcca gcctgggtat
    15181 ttgtttttat gttggctgtt ttaactacga tcatcaatct ttattcggta cggttattcg
    15241 cagaaacaga atattggctg gcttttgcta aaatcagtgt cattatctta ctgatcattt
    15301 ttgctactta tcttgtcggt cagcaaatgt tgggcacagg cgttttccct acccttcagc
    15361 aattgactga ccatggtggg tttactcctc atggtatgaa gggaatcatc agttctttgc
    15421 ttgtagttat ctattcttac ggcggttctg aactgattgc tatcacggta agcgaagcag
    15481 atgatcctaa acgtgcgatt cctaaagcaa tcaaaggtgt catgggaaga atcatttcct
    15541 tttacatcat tcctttgttt ttgcttttga ttctttttcc ttggaatact ttagcaggca
    15601 cgaatgtcag tccttttgtg atggtatttg aaaaaatgaa tatcccattt gcagcggata
    15661 tcgtcaattt tgtgattgtc cttgctttgt tctcatctat caattcgggt gtgtatgcat
    15721 cttcaagaat tttgttcttc cgtttgaagg atcgaaaagg ttcctctaga aaactagctg
    15781 ttttaaacaa gcatcaagta ccgcaacgtg ctgttttatt ttgtaccagt gttctttatc
    15841 ttggtgtagc tctttcttat tttgtcggtg acaaattatt tggctatctg gcaggttccc
    15901 tttcgtatac agtattattg atctggatca ttatcagtgc ggcatccttt gtactggcac
    15961 taagaaaagg aacattatgg gataaaggaa tcagcttttt tgcattagct gtcttaggat
    16021 tgattttcct tggtatcctg ttcacgaact ccattggggt aactgtattg actggcctgc
    16081 tttacctgtt catttatttc agttatcaaa aaaagaatga tgcgttcgta ttgacgaatg
    16141 aatgaaatcg atagaaaatt ttattttatt tatgtggaat agatggagct attgaagaaa
    16201 ggagttgtga caaaagtctt gttgcaactc ctttttccga ataaacagtc tcatgacctc
    16261 ttggtaaacg gtgttcaaaa accctctgtg caaaataatt gattgttctc catgctcatg
    16321 acatgataga agaaaggaat gaaaaaaagg agtttgtttt aaatgaaaaa gtattggaag
    16381 tttttgttga tgatcggtgt ttcaacggta gttatgtttg gtatgatgta cttgaatgtc
    16441 tatgcgctcg atcatatctt cttcagtcgt acacgagtat tcatggcgtt gatgatgggt
    16501 gcagtcatgg cagtcatcat gctgttgttc atgtggaaaa tgtatgaaaa caaaaagata
    16561 aatgttatga tcttagccgc tagtcttctt gtttttgccg gttccttgtt tatggtacga
    16621 agccaaacta ctgtcaacga cacagcttgg atgaaggcca tgattcctca tcattctatc
    16681 gctatcctgg caagtaaacg agctgattta aaagatcctg aagtaaaaaa attagcggaa
    16741 gaaatcattc aggcacaaga agaagagatc gacaaaatga aaaaaatgat caaagaaatg
    16801 gaatgaccat tatccgtcca aataaaaaaa gaggatgttc cagaagttat cagcttcaag
    16861 aaataagaag aagctacttc tggaacgccg tgaataaggg gttgtgaaaa agctgccctg
    16921 catcaagtaa taagaacagc caaacaaaaa tagcttctcc tatttttcgt ttggttaggc
    16981 ttattaccgc agatgcaagc ttttgaacac cgtttattaa gaggttgtaa aatcagcgtt
    17041 ctgacctgag tattagagag acaaatggaa aaatagttcc tcatattttg ccattttttg
    17101 agctaatacc gagggtcagc tgattgaaca ccgtttatcg agaggttgtg aaaaagtcgc
    17161 ttagtttcgc gtattaagaa aaattttgtg aaatggcttt ccacattttt gtataaattt
    17221 ggcttaatac cgagaaactg gcttttgaat accgtttatt cgtaaaaggg attgtgacaa
    17281 aagtcttgtc acaatccctt tttatgtttt tattgttcta attgcgctgt cttgcttact
    17341 gcttcttgcg gtttcacaaa tttttttgag attccccaac ctgtgaaggc actgaccatc
    17401 gaaaacacag gagaaagcaa actgaaaaat acgaatggca agtaagtgag tgtaggaata
    17461 ccaaatgtac ttgctacgaa acttccggca attccccaag gcactaagta gttgattact
    17521 gttccaccat cttctagcgt tctacctaat acagttggat caaatcctgc tttttcataa
    17581 gtttctttaa atgcattacc aggcagaata acagatagga attgttcacc aataaaaata
    17641 tttactccga tacttgtcat caatgttgta aaaatcaaat ttggtgtgtt cgtcatcttt
    17701 cttgatactc gttccatcac ggttgagatc aagccaaatt cgatcaacaa tccacctaat
    17761 gacaaagtta gaataatcaa tgacacagta ggcatcatac tttcgattcc tccgcggcta
    17821 agcagtgaat cgatttgttg gtttccagta tttgaaacaa accctgattc gatgacccca
    17881 gccaacttcg ttaaggaagt ttgtgggttt tgaataaaaa tcattcctac tgctacagcg
    17941 atattcaaca aaatcgttaa aattgccggc acctttttcc atgcacacag taacattaaa
    18001 aataaaggaa tcagtgacca gattgaaata gtaaagtttg cttctagaac atcagtcact
    18061 tcacgaatag atgaaagact tgcggcttta cttgtgtgtc ctaaaatcat gaataaaaag
    18121 aaagaaacaa caaatgccgg gacagttgac cacatcatat gcttgatgtg tttgaacaaa
    18181 tcggcatcaa caatagctgc tgctagattt gttgattcgg ataatggaga catcttatct
    18241 ccaaaaacgg cacctgaaac aatagctcca acaaccagcg ctggatttaa gcctagtgtt
    18301 gtcccaatac cgaaaaatgc aatcccaatc gttgacataa cagtaaaggc actccctaca
    18361 gcgctaccta cgattgcaca cacaacaaat acagaaggga caaaccactg gacactgatc
    18421 aatttgaacc caatgaccat tagagttgga atgatccctg cttgtatcca tacagcaatc
    18481 aatgaaccga ctaaaataaa aataaagatt gggatgattc ctggtttgat gccattgatg
    18541 attccttcgt gcagccaatc tgtcgggtat ctttttatca ctgcatacaa catgaccatt
    18601 ccgatcgctg ctaagatcgt gatattaggt gagaccttta atccgacaac gccaatcgca
    18661 atgcctaaaa caataaccat taatacaagt gttgcttcta aaaaacttgg tgttcctttt
    18721 tttcccatga taatctctcc ttttttagtt gttcttatgt tctaaaaaag ttaagatatc
    18781 ggattactcc gccgcaattc atccgcgatt cctcctttat aaaaataaaa agacctgttt
    18841 taaactaagg acgaatgact ccgcggtacc accttaatta aaaacagatc tgtttttcac
    18901 tttcaaactt ttattcaaat gtatggactt tccatgtaat tcgtcaatta ggcttgatcg
    18961 gttcacagcg accaccgact ttctgaacaa aacacctaac cgctactgcg tgaaaagttg
    19021 acttgtacga agtttacctt ccataagatc atttgtcaat gaaaaagaaa atattttttc
    19081 atttttctga aaattatttt tataactttc acacacaaga ttatttttta ctagaaagta
    19141 gcgccctctt gtttttttct tgctactatt tcttgatgtt cttgcttgat tctttctaat
    19201 agctttggct ctttcaacag atcaagagct gtattggcga gtagttctgc tgcaatcgca
    19261 atagaagcaa ggcctttgtc acttttagca gcagctttga attcttctgt gtgtccggca
    19321 atatatgtct cagagattgc taccgtaggc tggattgttg gtatgacttg gctgacattt
    19381 cctacatcag aagaaccgag acttgttctt tgttccgttt ctatttcttc atctggaaca
    19441 cctgcttctt ttgcatgctg gaagaataag tcatcaaaag aaggagtaac gatgacatca
    19501 tcaactgcat tttggaacaa tccaaactca aaagtcgtgc ccgtacttat cgcagcacct
    19561 cgtacgatat tttccacttt ttcatatact ttatctaatg tttgccgatt tcctgcacgt
    19621 aaatagaaac gtccagcagc gtaatctgga atgacgttgg cagctactcc tccgtctgta
    19681 atgatcccat ggatattgac atcttttggc aattgcaagc gtagagcgtt gattccatta
    19741 aacacttgga tcaatgcttc caaagcattt actccttttt caggtgctgc tgctgcatgg
    19801 gaagcgacac cgtaaaattt gatgtcgact ggatcattcg ctaaagattc tgtcgttttc
    19861 ccataacgaa aagctggatg gacgcataac gctacatcga catcctcaaa aaaaccttct
    19921 cgaacaaagc tgcctttagc tgatccgttc tcgccccctt cttcccctgg ggtgccatat
    19981 acacggattt ctccaccagt ttcatcaatg aattgcttca ctatgctggc ggctaatacg
    20041 gagtaagtac caaacaaatt atgcccgcat gcatgaccaa tacctggtaa agcatcgaat
    20101 tctgccaaaa aggcaattgt gggaccgggt ttattggaaa tataacgtgc atcaaaggct
    20161 gttcggtgtc cagctacttc tttttctacc caaaaccttt ctttttctaa ttgtttaatc
    20221 aacgctgctg aggaataaaa ctcatagtta cttacttcag gatgttcgtg gatatctaga
    20281 gcaagtgctt gatattctgg taaacgatat tggattagat ccttcaattg gtttgttgag
    20341 attgttgttg tcataaaaaa ttcctcctat gctagtcatt tttcttattt tctcccgaat
    20401 gtttcccatg caggcacgct tgatcctttt gatgttttct cgattacttt gactgtgtct
    20461 tctgtttgat aagcgtctac tattttttga tacgttttat tgttttcatc ttcttttctt
    20521 gcaacgatga tattcacata aggacgtgca tggtcatcca ctggttctaa gaagatggca
    20581 tcagaagcag gattaaatcc agcatctaca gctacaccgc tattgatcac tgaaatgtct
    20641 acatctgaca aagcacgtgc tgtttgggaa gcatctaatt cagaaatgtc tagatttttt
    20701 ctattctcgg taatatcaga aacagtgggc gcttgtcctt ttgccttatc cactttgatc
    20761 aatccagcag tttgcaataa cagaagagct ctgccgccat ttgtaacatc attagggatt
    20821 gctacttttg ctccgtcttt gatatcagct acatccttca aagtgttaga ataaattccc
    20881 agcggtgcat tgacagtatt tccgatcgat actaaatcag ttccgtgttc tttattgtaa
    20941 ttgtctaaaa agaattgatg ttggaaagaa ttcaaatcaa tcgatccatc tgctaaagcc
    21001 acatttggtt gattgtaatc tgtaaatttc acgtattcca aattaatgtt ctcctttttc
    21061 aaacggtctt tcacgttgtc ccatacatct gtatcttctc caataatccc tagttttacg
    21121 atagtttctt ttttgtcagt tgtatctgct tttccttggc tacaccctgc caaccaaata
    21181 attgctacaa atgtaatgac tacaaaacga ataatttttt tcattttttc tcctccactt
    21241 tcaatgtgta atttttttaa tcagttgatt actgataaat tgacttaaaa aaactaagat
    21301 tagaatcaat aatgtagcca caatcgttac atctgtttgg aatcgattat accctctcga
    21361 tatagcaaga ttccctaatc cgcctgcacc tactgctcca gccatggtag tcagtccgat
    21421 cacgttgatg atagtcaacg ccgagacccg aatgatacca ggcaaacctt ctaacaaata
    21481 cacacgtaaa atgataccga ttggactggt tcccatcgct tctgccgctt cgatcacccc
    21541 aggatcaact tctagcagtg cgttctcgat ttgacgagca aaaaacggaa caactccaaa
    21601 aatcaatggc actaaagctg ctttcgcacc aatcgtcgtt ccaactaaga aacgagtagt
    21661 caatgctaaa agagaaagca agataatgaa agggatggaa cgaatgatat tgatcagctt
    21721 atcaagtatt tcaaatagca gacggttagc tagtaatcca ttagggcgtg tcactactaa
    21781 cgtcacacct aagatgattc caatcatccc gccaatgaat gctgtccaaa aagacatata
    21841 tagtgtttgc ttcgtcgctt cgacaaattc atccggaatc aaataaacat tgggcaaata
    21901 tgttttaaag aaatcagtca ttttatcttc ctccttcgat cactttgata cgactatcta
    21961 aatcgttttt ttgtaaaata tttattttta caccagattt gatcaaataa tccaatgctt
    22021 ttttccgctg tttggtttct ccagctaaag taacgatcaa actccctaac ggcgtttctt
    22081 gtaataactc tacattgcca tataaaatat tcgctgttac ttgatatttg ctgtacagat
    22141 gagcgattag aggttcgttc gtctgatttc caatataact taattccacc agccatttat
    22201 tggcgatctg atcggcaaaa gcagaatggg caatgatcgt ttctaatgct tggtcaagat
    22261 gagtagctgt tcgaataaaa tctttggtca attcttcttc aggattgctg aagatctgga
    22321 tgctgctacc tttttcaacg attcttccat cttccataac cgctaccttg ttgcagattt
    22381 ctttgacaac ttgcatctca tgagtgatca ggacgattgt taaacctaac tggcgattca
    22441 atttttttaa caatgcaagg atctgaaggg tcgttttcgg atcaagtgca ctggttgctt
    22501 catcacataa taatacctta ggttcattcg ccaaagctcg tgcgattgct actcgttgtt
    22561 tttgtccccc cgacagttgt ttaggataag cagatgcttt ttcttccaaa ccgacaagtt
    22621 ccagtagttc attcactttt tgacgacgtt cctgtttcga ttttccagaa tactttaaag
    22681 aaaaatcaac gttgtcaaaa atagttcggc tttccattag attgaaatgc tgaaagatca
    22741 taccgatggc ctttctttct tttcgcaatt ctttgggaga gagctgactc agattcgtct
    22801 gattgacaat gacttctcct gctgttggtt tctgcagcaa attcatcaca cgaactaacg
    22861 tacttttccc tgcacctgag taaccgacga ttccataaac atcgcctttt tcaatcgtta
    22921 aatctacaga atctactgcc tgtatctctt tttctttttg tttgaaacat acagaaacat
    22981 ctcgcaattc aatcattaaa attcctcctt atctaaaaaa agcgtcctca agaaaatgaa
    23041 aatgtcattt tcttgaggac gcttttttgc gtgttaccac ctcatgttca agctgtgttc
    23101 acacacaact cctcttcaag tacgatcata ctctagcaag atatcggtcg cagccgtcat
    23161 cgccttacat ctatgctcgg gatgaattgc tcgatggcca ttttccaata gtcgttcctt
    23221 gcttcttctc agctaccgaa gctctctgtc aaaggttctt ctatcgtact taccatttca
    23281 atgcaaataa tattcaaaaa aaaagtcctt ttactaacat aaactatgtc agtaaaagga
    23341 cgacgtatcg cggtaccacc ttttttcgga agtttccttc cctcaagccc aacatctcaa
    23401 aaagagagat tggcgttcgt tttaacggtc gaacagttcc gaatttgcct acttatcgac
    23461 aaattattct ccaaggccat tttcagcttt tcttacttga ctcttctcac cagccagagc
    23521 ctctctgcaa agtttccaaa cttactttcc ttttcaacga aatcgatatt ttgttgttgg
    23581 gattaatcta catgaggaaa actgaaaagt caagtacgaa attcaaatta ttttttctat
    23641 atttattttt ctgttttttt atttaacatt tcaataacag ttcgaagatc ttttccttcc
    23701 gcaagaagtt tcaatttttc cttttcttcg acggtataat ttcggacaaa actggaatca
    23761 ggtatcaaaa caacgcctaa tcctgctcgt gaagcagctg ttgctcctac taaagaatct
    23821 tccactgcaa aggctgaact agcttctaat cctgttcgtt ccaaagctgt cagataagga
    23881 atcggtgaag gcttgttctc cgacacttcg tctccgaatg taaacgtgtc caagtaatca
    23941 gctaatttaa agtgatccaa gatatctgtt gctcttttcg taacagtggt cgtagcaatg
    24001 cctagtttca tatgacgttc ttttaagtct gccaatattt cttttgcata tggttttaag
    24061 tggatggctc cgcttgtcag ctgttgataa aaatattctt cacgcttcgc tcggacttcc
    24121 tgtacttttt cagggctacc tgctgctttc actaaaatat caaaactttg tttccagttt
    24181 tttccgcccc aagcgtcaac gatttctttt gggatatgga tatcaaattg ctgaaatccc
    24241 caaagccagc catcacgata cgttttttct gtgtcaacta acaaaccatc taaatcaaat
    24301 attgcacctt tcatctatac attaatcctt tccaaaacaa tacacatagt ttagcacgac
    24361 tggtccaaaa agaacagaag caaagaacca gccttctcgt ttataagagt tcttggaatc
    24421 gacggatata gattttcttc acagctgtca caagcgccag ataagcgatg actgtagcaa
    24481 ataaccataa ccagtaattg ccaggaagtg gcatcaagcc taattcagca ccaaaacttg
    24541 taaaaggaag gacagaaccg acaataattc ctaatgtagt gataacaaac atggcaaatg
    24601 ttgcgttgct ttggataaat ggtactttcg gtgtacgcag tgcatggagc actaaggttt
    24661 gtgtccatag tgattcgaca aaccatcctg catggaataa tgcgatgaaa atcactcgct
    24721 gtgaactatc caatgtatgg aaacttccgc ccactacagc aggacaaata acaaaataca
    24781 tcaacaagta agtagtaata tcaaatatcg aacttgttgg accaaagtaa accatgaatt
    24841 ccccaatact agatgcattc catttttttg gctcgtccaa atattcttta tccatccgat
    24901 cccatggcaa ggaaatgcag gaaacatcat agatcagatt caaaaacaaa agttgtaaag
    24961 gcagcattgg taaaaatggc aggaacgtac ttgcaatcag cacggaaaac atattgccaa
    25021 aattagaact tgctgtagcc ttgatatatt tcatgatatt cccaaaagtt tctcgtccag
    25081 aaagaaggcc tctttccaaa atcgtcaaat ctttttctaa aaggatcacg tctgcagatt
    25141 ctttcgcaat atccacagct gtatctacag aaataccgat atcagccact ttcattgcag
    25201 gagcgtcatt gataccatct cctaaaaatc cgacagtatg accattttta cgtaaagctg
    25261 tcgtcaaacg tgctttttgc tgaggattca attttacgaa tacttcatgg tcttcagcta
    25321 cttgtgctaa ttcatgatca ctcatttccg agattttctc accggtaacc aattcattga
    25381 tctctagacc tacttgacgg cacactgaac gtgtaactaa ttcgttgtcc ccagtcagaa
    25441 cttttacagc tacaccatgt tctttcagag ctttcaacgc ttgtttcgtt gtttcttttg
    25501 gtggatcaag gaaagcaaga taaccaatca aaaccatgtc tgactcatct ttgactgaaa
    25561 attctccaac gacgcttgga ttggtctttt gtgcgacacc aatcactcgt aagccatctt
    25621 cattaagtga ctgtactttt gcaagtacgg cttcttttcg ttcttttgtt aatggtgtaa
    25681 cagtaccgcc aagatcaata aatttagaaa tgttcagcat ttcttcaatc gcaccttttg
    25741 tgatcatttg tgttttacca gctggatcag caaccacaac actcatacga cgacgttcaa
    25801 aatcaaaagg aatttcatcc actttttgat aattgatctt atctgtatct aaagtttctg
    25861 ttgcttcatc aatgatagcc acatctaaca aatttttcag ccctgtttga tagtagctat
    25921 ttagatacgc atggcgcaaa acacgatcat cttcatttcc ttcacaatcc atatgatatt
    25981 caagaatgat tttatcttgt gtcaatgtcc ccgttttatc cgtacataac acatcgattg
    26041 caccaaagtt ctggatggca ttcaaatttt tgatcactgt tccttttttg gccatcacac
    26101 ttgctccttt gaccaaattc gtcgtaacga tcattggaag catttcaggt gttagaccaa
    26161 ctgctacaga tagtccaaaa agaaaagctt ctagccaatc cccttttgta agcccattga
    26221 tgacgataac tgctggagcc atcaatgaca taaatttgat cagtagcatg gatgttttat
    26281 ggatgcctaa ttcaaagctt gattgaattg gtttttcaga tagcgtttct gctacatgac
    26341 caaatagtgt ttcatttcca acagaaacaa tgattccttc cgcacttcca ctgatgacat
    26401 tacttcccat aaagacaaga ttttcgtaac ttgtttcgct ttgctgatcg tcttcacata
    26461 ctttcgcatg cttttctact ggatagcttt cccctgtcaa tgctgcttgg gaaatgaata
    26521 aatcctttgc ggacaataaa cgcatatccg ctggtatcat atcccctgct gaaagccgaa
    26581 caagatctcc acagacgatt tcttccatag gaatctctgt gtactttcca ttacgtttta
    26641 cagctgccgt tactttcaca agtgatttca gtttttcagc cgcttgattg gaacgtacgg
    26701 actgaatcaa cgtcattgtc ccgctgacga taaccatagt gaagataatg gctacaccga
    26761 aaagatcttt atctccagga gctgctaata catattccgt gatgaatgaa ataattccta
    26821 atgcgatcaa cactaatgta aatggcgtga tgtatgcttt caatatttct acaatgaatg
    26881 gtgttttttt gccatatgaa atcgcatttt caccgtaatt ttctcttgaa cgttcgattt
    26941 gttcttctgt caatccattt gctgatgcat ggaatagttc aaataattct tgtttcgttt
    27001 ttccagcaaa agctgcatag attttttgtg tatctttctt tttttccatc tcaatctctc
    27061 ctttgtgtcc aaaagacagc tgttctcgct gcttttggtc tttagctatt catcggatcg
    27121 atagagaaaa aactgaaagg ggctgagaac agatagataa tagccctggc ctttcctcta
    27181 gatccttgtt tttcgaatga ctgtcatcca tttgttctca tctcctttac taagtaattt
    27241 taattcatga cttccaatca tttttcgaat agttattttt ccaattagac cacctccttt
    27301 ttatttttca ccgatgggga tttgcggcaa caaaaaaacc tctcgccaaa tactcagcga
    27361 aaggtttgaa aaagcatatt aaaaaaagct tctcagatct catcgttgag ttttgacact
    27421 gtacaacgta aaaagcagat acctgctttt agctacctta tgaaaagcct tatctcgaca
    27481 attcctgttc tacccattgg cgtctctcga cgtttttggg cagtagccta tgtttgtata
    27541 ggagcctcac ctaacaaatc ttattcggtt ttccttcgtt aatataacaa ctaaaaaaga
    27601 ggatgtcaaa tcaattttcc atgtttttca tacttttttt aaaatacaca cgttatattc
    27661 ctgtctcacg cggttttatt tgtctcattt tccacctccc gctataatag aaatatagta
    27721 ggaaacgagg tgctgttatg gaaagaacac ttgttattat caagccagac ggcgtgagac
    27781 gccatttagt cggaagcatc atccaacgtt ttgaagcaaa gggactggcc attgctgaaa
    27841 tgaagtttga aactatgact cctgaattag caaaagaaca ttatcagcac ttgactgagc
    27901 gcagtttttt tgatgaactg atcgattaca tgacttccgg tcctgtcgtt tatcttgtgc
    27961 tggtcggcga ggaagtgatc gatatcgtcc gtaagatggt tggagcaaca aaagctgccg
    28021 atgctgttcc aggtacgatc cgaggagact acgcgctgcc ggggactgaa aacatcattc
    28081 acgcttctga ttcccgtgat gctgcggtaa aagagatcgc ccgctttttc ccgccattcg
    28141 atataaacaa accgtctgaa aaagcggcga agtgatacaa attctaaact gctggtctag
    28201 ttgctgggtt cagcaatggc cagcagtttt ttctctaagg acctccgttg attctttcct
    28261 aacatatatt cgagcactgt gaagaattct tggtagtctt tcgtcttttc ttcccctaaa
    28321 gcagcagaaa tcaatctttg ataataatct gccatcaatg tttcatagat cactgtactt
    28381 ctttctttat gtgctaagct ccgtttcata tcttcattca cactacgtgc ctttttcaac
    28441 cgaccatttt ctatataaaa cgaagtcagg ttcattaaaa aagtaaagag atactgctca
    28501 tgattgttca actgtgctaa tcgtcgcatt ctttttttga ttttcaaata attgttctca
    28561 atgaaccgat cactgaatat ccaaggaaaa tcagctagaa tagatagttc aaattgacca
    28621 tagtctggta tctgcatcaa gtattcttca atgattcggc attcataacg taaaaattca
    28681 aattctgtct cagatacttc tgttttttcg accatgtgaa gattcaaaac caaataatac
    28741 agatcttctg ttttcttaaa atgcctacgg ttattgctga tctctttata aggatcaaag
    28801 ctgtcttctt gtacccgatc tagcattcgt ctttttttct ttaactttat tggttcatcc
    28861 agctggtttc gcatccattc atattctgca agtgtcatgt tcattcgctc taaaaatgat
    28921 ctcaatgtta caaatgacat ttttttcact gaatttgtct caatcccgac tagagaagtc
    28981 ttaaaacaga ttccttccgc taattgggac tgtgtcaact tcttgttgac tcgaagtttc
    29041 ttgatcaatt caccatcata cataatagtt ctccttttta atttaaattt ttccacattc
    29101 aataaataga tacgttaaaa aggaaaaata cacgaaaaaa ataaaaaaat gtttttttca
    29161 taaaaaatac caaccttcaa gcattagaat gttgtctaac tactgaaggt tggtttgatt
    29221 gtttattgat tatttttttg ctgttcaacg tctgttcttg ttactggata taagttggtt
    29281 gttgttttat taccattttt tgaaaagaca cttgtcgaat gttcgccttt ttgcttttcg
    29341 attgcttcat tacgttccgc ttcattttta tagtcatatt ttttcggatc aatcgtctca
    29401 aatccgtttg gcacataaaa ccgcaagaga ttttcctgat tcagcttatc tgaaagactt
    29461 aacgcagtct tgactttttc ctgatctttg gagatttcct catcgattcc tgctgctttc
    29521 gtatcgatga tttctcctgt ctgattattg taagcttttc ctcctaggac ggtgtatttg
    29581 ggtgtcacaa agttcccatt tcgaaaagca actacttgat catgctgaga agataataag
    29641 tctgtaccaa aatgaagata atctttatca tcgattccca atagatgtag taatgtcggc
    29701 aaaacatcga tttctccacc gtattcatga ttgactgtcc ctttagtata accaggcata
    29761 tggatcatca atggcactcg ttgcatctgt gcgttgtcaa attcatccca tgtatctgga
    29821 tctttaccaa gagcgcttgc taaatcttta ttatctgtat tcgagatccc aaaatgatcc
    29881 ccgtaaatca caaagattga attttggtaa ataccagatt ttttcaaata cgtaaaaaat
    29941 tgttccaatg attgatccag ataatgtgcc gttcgaacat aattatctac tgtgctattg
    30001 ccagtattca aagatggaaa gtcgaaattc ttgtcatccg tataataagg cgtgtggttg
    30061 gttacggaaa gaaatttcgt gtaaaacggc tgttgtagat gctcaagata ttgggcagat
    30121 tctctgaata aatctttatc taatatccca taacctaacg tttcgtcgga ttcatcaaaa
    30181 taagatcgat caaagaaatt gtcataacct aagtttttat atacatgatc tctattccaa
    30241 aaactagcta cattcccatg gaaaacagcg cttgtatagc cttgcttttg tccaaggatc
    30301 gctggtgcgg cttgaaagac attgtctgac ccaagttctg tgaataatga gccttgaggt
    30361 aaaccaaatg tgccagtttc caacatattt tcagcatcac ttgtctttcc ctgtcctact
    30421 tcatgaaaga aattgtcaaa gctgatcgtt gcttgattct ggaaaatact atttaaaaac
    30481 ggtgtgactt cttgtccgtc taccttcata ttaatcaaaa actgctggaa actttctaaa
    30541 tggagaacga tcacattttt ccctttagcg atcccaaatg tttcgggatt tggctctgca
    30601 taatgtttct ttgtataatc taaaacttca tcaatcccat tactgcttgc atgcgcgcga
    30661 acactgctag tcattcctgt tttgattccg tcataaatag tatacgcatc gattcctaga
    30721 tatttgacaa tatatgaacg gtcaaatgtt cgctgcagca attgtggacg gttggcttcg
    30781 ctcagcgcta gatttcctga aaaaataagc cctgaaagac aggtaacagc gatagccatc
    30841 ggtttgccga cagggttgct tttgataggt attttcttga ccttcaacca aaccagtagc
    30901 ccaatgaaca cagcgatatc cagccagtag atgacatcat ggggcttcat caaagaaaag
    30961 gagcttcctg acaatccttg cgacactttc gaaaagccta atacagattt gactgtaatg
    31021 aaatctgtga attcccgata aaaaataata ttcaagtaca acaaaagcgt atttaaaata
    31081 tcaatgatca aaagaatagc taacgctggc tttggctttt taatatacaa agaaaggcca
    31141 aaaaacaata aggtagtcgc aattgggttg atccacaaga taaagtactg gatcgtacct
    31201 tccacaccta atgaaaaatc tgcatagtag gcaatgatcg tcttcagcca gaaaaagaaa
    31261 acagctgtca aaacgattgc taaacgattt tggcacaatt ttttaagttg tgtcacgtat
    31321 atcacttctc tctattcaca ttttttctta ttttgctcct gaaaaatgaa aatttcctaa
    31381 aaaagttgtt atcttaagat ttttttattc tttctaaaga ttattccgtc cacttttcac
    31441 agcataaaac cgctgcgatg taagcgatta aactaatgaa gagataaaag tcttgtggtg
    31501 accgcttcac tccacggtat tcaaaagcca gtttctcggt attcgtacaa aaaaagaggc
    31561 tgtgacaaaa ttcttgtcgc agctccttat ttcttgatgc aggacagctt tttcacaact
    31621 tcttccttaa acggtgttct cctgccaact cctcggccac aagtcacaat atttataaaa
    31681 catgagaagc tgttttttga aattgttcct tgtggctcag agttaaacgg caggctcaag
    31741 acctcttgat acacggtgtt caatcagctg accctcggta ttagattatg tcaggacgct
    31801 aattttacaa cctcttggta aacggtgttc aaaagcttgc atctgcggta ataagcccaa
    31861 ccaaacgaaa aatataagga gctatttttt gaaattgctc cttgtggctc agagttaaac
    31921 ggcaggctca agacctcttg atacacggtg ttcaatcagc tgaccttcgg tattagctca
    31981 aaaaacggca aaatatgagg aactattttg ccgtttgttt ctctaatact caggtcaaaa
    32041 cgctgatttc acaacctctg tttttcattg tccataggat tgatattgtc cttgtgatga
    32101 ctcattcgta ataattgagg cttgattttc ttcacttccc gttatcgttt gtccactgcc
    32161 agaatctgaa ggacttgttc ctgtcgactc gtttttttga gaagagacag ttgttttctt
    32221 gacttgttca tttgtctttt tccattccgc taaacgatcg gcgaccactt ttttgtctac
    32281 tttttcagaa taagcggtga tcacttttcc atttttcaaa cgggctactt tgtcgccatc
    32341 atgagtcaaa agcaaaacgg tcaaatgctt gtctttaaat tgatattgtc tgagagaaat
    32401 cgcactaagt acgtcatcga tattaataaa ttgattttct tcttttcctt ttggcaaata
    32461 aatgtccaat tcgccttttt cgtaattggc agttatttta tactccgccc accaataagt
    32521 tgagaattct tttttgaaat tatctactga ttctttgctt gctacgattt tttctgtttc
    32581 tttctgagca agatctgctg tcatttttcc tgaaaatgct gcggataaaa taagcagtaa
    32641 gaaaaaaccg aataaccaaa agagaagaaa cggtcttttt ttcctcatgc tttcctccac
    32701 tcctatttaa ttttgactat tctattatat acaaaaaatg aaatagaaag acaaaaaagt
    32761 tgaaaaagat cgtaaataat tgaacttctt tttcacaaaa tggtaagaat ggagaatttc
    32821 acgcatttgc tctcaactat tctttcttaa gcctcaaatc cgtttttatc tgatacgtct
    32881 ttgaaccaat gacccgattt tttgattgtt ctttttccat cttgtgctaa gtctactgaa
    32941 ataaagccat atcgattctt atatgcattg gtccacgacc agttatccat acatgtccac
    33001 atatgatagc ctaaacaatt ggcaccttct tgaatggctt gatggacata tttcagatga
    33061 gattggacaa attcgatccg ataatcatcg tggatcatgc catcttcttt gataaatcgt
    33121 gcttcgtttt ctacacccat accgttttca gaaataaagc agtcgatatt tccataatga
    33181 tctcgtacat tgatcaaaat atcatagatt ccttgttcat agatctccca tccgcgataa
    33241 ggattcattt tacgaccagg catttcataa ttgtcgaaat aatcctcagg cattggaccg
    33301 tttttagtat cgattggtgt ttcttttgct tttacccggc gtggctggta ataattgata
    33361 cctaaaagat ctactgtatt ttctttgata accgtcaaat cctctgcatg gatcacaggc
    33421 atgagatcaa gttcttttac tatctcaatc aattcacttg gaaactcgcc ttttacagct
    33481 ggatcaagga atgaacgatt gaagaacgca tctgctattt gcgctgcttt aacatcttca
    33541 gggtttgatt cgtctcttgg atagcttggt gtcagattca agatgatacc aataacacca
    33601 ccttgctcca tttcatggta agatttgatg gctaacgctg aagccaacgc ttcatgatag
    33661 ccaacttgga tcgctttttt catatctgac tcttctggat aatgccatcg atataaataa
    33721 cctgcttcga ctggaacgat tggttcatta tgagtaaacc atttttttac tttcgaacca
    33781 aacaattcaa aacaactttt ggcatatttt tcataggctt caaccgtttc tcggttcaac
    33841 catccgcctt tttcttgcag atacatcggc atatcgaaat gatacagatt cacaaagggt
    33901 tcgataccgt tttcaatcaa ctcatcaaaa taacgatgat agaaacgaac ggcttcttcg
    33961 ttgattgttc cagattcatc aggtatcaaa cggctccatt ggatagatgt tcgaaatgaa
    34021 ttatgcccag tctgtttcat caactgtaca tcctcttgat acttcgtata aacttgcgag
    34081 gttttttcag gtcctacttg atcaaagaac ttttgcggtt cttttttgta ccaataatca
    34141 aaaatgttct ctccttttcc atcgcctgaa atccttcctt ctgtttgtgg gccacttgct
    34201 gcagaacccc accaaaaatt tgctggaaat tgatattttt tcatcaaagc acctcttttt
    34261 cttttttagt tcgttttagt tgattccatg tatgatattt tccatcacaa tcactttttc
    34321 attttcttcc tcttcttttt tgattcgttt taacagctgt tctgctgctc gttccccgat
    34381 tttatctgtt ggtggcgtga tcgtgatttt cggaaggata ctcagatcgt ttttatctaa
    34441 ataatcatag tgactgaacg caatatcctt cccgattctg acaccttctt gattgaaaca
    34501 ttcgatggca ccaatcgaca tattgtaatt gctgacaaaa atagcagttg cccctttttc
    34561 taataatgct tttgccccgt aatagccgct ttttctagaa tagtctcctg taaagacctc
    34621 taattggatc gatggatcat tttggaccgc ttctttggct cctgctaaac gttctcttgc
    34681 tacgtagtct gtttgagtgg cagcaataaa tccgattttt ttatgtcctt gttcaccatg
    34741 atgagcgatc acttttgcta cactttctcg atcattcact aatattgtat caatacctgc
    34801 tggtccttct ggacaattca atgcgataac tggaatactc atttttgtga gcatttcaaa
    34861 tccagaccac tcttcttcgg ataagaagac aatcagccca tcgatcacat gcttcatcag
    34921 gtattcaatt ttttgttcaa ttttttctgg ctgatcggca aacccgctta ataataagct
    34981 atacccattt tcttcagcta ctctttcgat ccctgagaca acttccgacc caaaacggct
    35041 ggaaatcccg tttatcaaaa gtccaataga gaagcttcga ttattcttca accctttagc
    35101 aatgatgttt tctttatagt ccaacgctga aatcgcttct gctatttttt tcatgttctt
    35161 ttccttcagt tgctgaccat tcaagtaacg ggaaactgtt cccactgaaa caccagccat
    35221 cttagccaca tcacggatcg atgccataca ttctcactcc tgccagttac atttgatttc
    35281 tctttcttgt tgttcgatta tgatgaccgc attctttgca tagtgttgct tgtcatcaat
    35341 atccatataa ctaaagtctt cagtagagca acttcctctc actattaatt atacttaaac
    35401 aagtatttga accggttcat ttttaatata gcattttttt aaaagattgc aacacttttt
    35461 taaaacgctt tctgaaagtg gcggattttt tgccttttta aaattttatt ctaaaattta
    35521 ctctatttgt gggtgttttg tgcgtttttc tcttccatcc gtttgaagtt ttacattcca
    35581 atggtataat ttctttatcc tatcaaatgg gggaagtatt ttgaagaaat taatcgtact
    35641 atttattttg tctgcgggac ttttgacatt gactggctgt gatttgtttg gcggctctga
    35701 ccaatcctcg gacgaaacaa ccgattcttc tgtcttaaaa gcggaaaaag cagataccac
    35761 caacagtgta tatacgctaa aagtacgtaa agatatggat ttatccgcgg gacagttgac
    35821 atttacagat aaaaaaatgg aatggacacg cacgtatcag acacaaggaa ctgattcttc
    35881 tgaatcatct gaagaaaaaa cagtgctgac agatatcaag atcactacca aagatgacga
    35941 atatattatt tcaggaaaag aaaataaaaa agaaacaaca gtcatattta caaaaatcgg
    36001 taattaccgt ttgaaggatg aggatggcaa catctacagt ctatagtgcc gtctgttgga
    36061 tcttcttttg tttctcccct tcttttctgc tatagtaaag aagcaagatg attgtaaagg
    36121 agacgaaatg gatgatcgat agtcctgatt attgtacatg taataacaac aaaaatatcc
    36181 atacagaatt taatgaccaa ggaagcttga gcatatgcga caactgtcac aaactagtca
    36241 aagattcatt taaaacattt gaatcttatc ctgttcaaaa ttatgtaaaa agtagaagaa
    36301 gataaacaaa tccaagcaaa actcactatg gctgattttt atgaacttca aactcagctt
    36361 cttcctttga tcaagcttca tcagtaaaac aaacagtgga tcatttcagt ttacaaatca
    36421 aagagtaaag atttatttat ttcaaatatt tgaatataaa ataaccaaac gatagaaagg
    36481 cttattctac atcacgtagt aat
//
LOCUS       DAZUJR010000019        34952 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.019, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000019 DAZUJR010000000
VERSION     DAZUJR010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34952
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.019"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            153..1859
                     /gene="efbA"
                     /locus_tag="ACG804_000878"
     CDS             153..1859
                     /gene="efbA"
                     /locus_tag="ACG804_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HFS4831826.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            complement(2017..2919)
                     /locus_tag="ACG804_000879"
     CDS             complement(2017..2919)
                     /locus_tag="ACG804_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFS4831827.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(2916..3608)
                     /locus_tag="ACG804_000880"
     CDS             complement(2916..3608)
                     /locus_tag="ACG804_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HFS4831828.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            complement(3651..4292)
                     /locus_tag="ACG804_000881"
     CDS             complement(3651..4292)
                     /locus_tag="ACG804_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbR-like 5'-deoxynucleotidase"
                     /protein_id="HFS4831829.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            complement(4330..4644)
                     /locus_tag="ACG804_000882"
     CDS             complement(4330..4644)
                     /locus_tag="ACG804_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831830.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            complement(4632..5261)
                     /gene="pyrE"
                     /locus_tag="ACG804_000883"
     CDS             complement(4632..5261)
                     /gene="pyrE"
                     /locus_tag="ACG804_000883"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HFS4831831.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            complement(5268..5984)
                     /gene="pyrF"
                     /locus_tag="ACG804_000884"
     CDS             complement(5268..5984)
                     /gene="pyrF"
                     /locus_tag="ACG804_000884"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HFS4831832.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            complement(5981..6913)
                     /locus_tag="ACG804_000885"
     CDS             complement(5981..6913)
                     /locus_tag="ACG804_000885"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HFS4831833.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(6910..7686)
                     /locus_tag="ACG804_000886"
     CDS             complement(6910..7686)
                     /locus_tag="ACG804_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HFS4831834.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(7740..10925)
                     /gene="carB"
                     /locus_tag="ACG804_000887"
     CDS             complement(7740..10925)
                     /gene="carB"
                     /locus_tag="ACG804_000887"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HFS4831835.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            complement(10930..12006)
                     /locus_tag="ACG804_000888"
     CDS             complement(10930..12006)
                     /locus_tag="ACG804_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HFS4831836.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            complement(12011..13291)
                     /locus_tag="ACG804_000889"
     CDS             complement(12011..13291)
                     /locus_tag="ACG804_000889"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HFS4831837.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            complement(13310..14236)
                     /locus_tag="ACG804_000890"
     CDS             complement(13310..14236)
                     /locus_tag="ACG804_000890"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HFS4831838.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            complement(14249..15532)
                     /locus_tag="ACG804_000891"
     CDS             complement(14249..15532)
                     /locus_tag="ACG804_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HFS4831839.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            complement(15546..16085)
                     /gene="pyrR"
                     /locus_tag="ACG804_000892"
     CDS             complement(15546..16085)
                     /gene="pyrR"
                     /locus_tag="ACG804_000892"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HFS4831840.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            complement(16320..17231)
                     /locus_tag="ACG804_000893"
     CDS             complement(16320..17231)
                     /locus_tag="ACG804_000893"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFS4831841.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            complement(17228..17692)
                     /gene="lspA"
                     /locus_tag="ACG804_000894"
     CDS             complement(17228..17692)
                     /gene="lspA"
                     /locus_tag="ACG804_000894"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HFS4831842.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            complement(17697..18395)
                     /locus_tag="ACG804_000895"
     CDS             complement(17697..18395)
                     /locus_tag="ACG804_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HFS4831843.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            complement(18382..18768)
                     /locus_tag="ACG804_000896"
     CDS             complement(18382..18768)
                     /locus_tag="ACG804_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831844.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            complement(18915..20585)
                     /locus_tag="ACG804_000897"
     CDS             complement(18915..20585)
                     /locus_tag="ACG804_000897"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HFS4831845.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            20768..21001
                     /locus_tag="ACG804_000898"
     CDS             20768..21001
                     /locus_tag="ACG804_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFS4831846.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            complement(21100..21531)
                     /locus_tag="ACG804_000899"
     CDS             complement(21100..21531)
                     /locus_tag="ACG804_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HFS4831847.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            21610..22023
                     /locus_tag="ACG804_000900"
     CDS             21610..22023
                     /locus_tag="ACG804_000900"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HFS4831848.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            complement(22061..23209)
                     /locus_tag="ACG804_000901"
     CDS             complement(22061..23209)
                     /locus_tag="ACG804_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFS4831849.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(23331..23927)
                     /locus_tag="ACG804_000902"
     CDS             complement(23331..23927)
                     /locus_tag="ACG804_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFS4831850.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            complement(24127..26769)
                     /gene="alaS"
                     /locus_tag="ACG804_000903"
     CDS             complement(24127..26769)
                     /gene="alaS"
                     /locus_tag="ACG804_000903"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HFS4831851.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            27157..27588
                     /locus_tag="ACG804_000904"
     CDS             27157..27588
                     /locus_tag="ACG804_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4831852.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            complement(27633..28982)
                     /locus_tag="ACG804_000905"
     CDS             complement(27633..28982)
                     /locus_tag="ACG804_000905"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFS4831853.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(29052..30215)
                     /locus_tag="ACG804_000906"
     CDS             complement(29052..30215)
                     /locus_tag="ACG804_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFS4831854.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            30344..30667
                     /locus_tag="ACG804_000907"
     CDS             30344..30667
                     /locus_tag="ACG804_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831855.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            complement(30850..32199)
                     /locus_tag="ACG804_000908"
     CDS             complement(30850..32199)
                     /locus_tag="ACG804_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFS4831856.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(32268..33221)
                     /locus_tag="ACG804_000909"
     CDS             complement(32268..33221)
                     /locus_tag="ACG804_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HFS4831857.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            complement(33323..34513)
                     /locus_tag="ACG804_000910"
     CDS             complement(33323..34513)
                     /locus_tag="ACG804_000910"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008890 - glycine C-acetyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HFS4831858.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            complement(34713..>34952)
                     /locus_tag="ACG804_000911"
     CDS             complement(34713..>34952)
                     /locus_tag="ACG804_000911"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831859.1"
                     /translation="KNRTVTRLLSQSFFRIQQVKLLRNIQRVKLKIADKRRWKFYVFL
                     LVYAINKLNIQNTIDFNERASINGCVVFICPGRVK"
BASE COUNT         9948 a         7638 c         6119 g        11247 t
ORIGIN      
        1 taaaaatttg gatttcaacg atagaaacac tgttttttat gtaattagtc caagattttt
       61 ctagactttt gctttactat tcggccaaat tggtttttct tctttttttc gttataatga
      121 atatacttat gaaaagaaat gaggaatgaa ccatgtcctt tgatggtgta tttacccacg
      181 cgatggtcaa cgaattgcgt gaaacgttac tatctggccg gatctcgaaa atccatcagc
      241 cttatgaaaa tgaaatcgtg ctggtgattc gttcacgcgg caaaaaccat cgattattat
      301 tatctgcgca cccaagttat gctcgtgtac agattaccca aatcgattat cagaatcctg
      361 ataatccgcc taacttcgtg atgatgcttc gaaaatattt ggatggcgct attttagaag
      421 acatcgaaca aatcgaaaat gatcgagtga tccatttcca ctttgctaaa cgaaacgagt
      481 tgggtgatct acaaaatatc atattgatcg ttgaattaat gggacgtcat agtacgatcg
      541 tcttagttaa tcgagaaact ggaaaaatac tggatgcgat caaacacatt ggaagctctc
      601 aaaacactta tcgttctttg cttcctggtg tagaatatgt tgctccgcca aaacaagagg
      661 tcttgaaccc atttagctcc gagaaagaaa aaatctttca gcggctttcc caaactgaac
      721 tagatccaaa agcaatccaa cgtcagtttc agggaatcgg tttcgatatc gctcaagagc
      781 tgaccaaaag attactggaa cgtcctaatg aaaagatggt tgtatgggac gaatttttct
      841 cagccatcag ccatcagcct attcctactt tttacgaaac ggaaaataaa gattttttca
      901 caccgattgc ttatcaggta ttgtccgaac aggcatctgc tgtaacagct tatccaacac
      961 tcagtcaatt attagatagc tattatcacg aaaaagcaga gaaagatcgg gcaaaacaac
     1021 aaggcggaga actgattcga aaaatcgaaa atgaactaaa acgaaataaa aataaattga
     1081 aaaaacgtga acaaacactc aaagaatccg aaaacgctga gaattaccgt agaaatggcg
     1141 aactacttac tacttttctg acacaagtac cacgcggcgc aaaagaagtt gttttaccta
     1201 attattatga agaagatcgg ccaatcaaaa tagcactaga tccggcattg acaccaaatc
     1261 aaaatgcaca gaaatatttc catcgatacc aaaagctgaa gaacgctgtt aagctgattg
     1321 gcgaacaaat ccaagaagcc aaagatgaaa tccaatatct tgaatctgtc ttatctcaac
     1381 tggaaattgc cggcccaatg gatatcgaag caattaaaga agaattgact tcagaaggat
     1441 acctgaaaaa gaagaactta aaaaaacaaa aacgtaagaa accatctcag cctgatcaat
     1501 acttttcttc tgacggaacg ctcattcttg ttggtaaaaa caatcttcaa aatgaccagc
     1561 tgacaatgaa gacagctaaa aaaaccgact attggcttca tgcaaaaaat atacccggtt
     1621 cgcacgtcat cattaaaagt gacaagccct cagatgaaac aattacagaa gctgccgagt
     1681 tagctgccta tttttcaaaa taccgatact ctgcccaagt gccggttgat cttgtacagg
     1741 taaagcatat ccgaaaacca aatggcgcca agcctggtta tgttatttat gaaaaccaaa
     1801 agacgattat cgtgacacca gaagaagaaa aaattacagc tatgaaacaa aacaggtaat
     1861 caatgagtgt ttctagaatc atatttgcgt actttcccac aacagcaatt agttataaat
     1921 tgtttgctac aaaaagagga gttgtgacaa aattctgtca caacccctct tttttgatca
     1981 acggtgttca ataaacagcg ttctcatctg cttttcttag ctctgctggt ccagtaaccg
     2041 agtaagctct ttgataaatc tttgagcgat ttcactgagc ggacgtttcg ccgaataaat
     2101 gatataaaat tcatttagtt cgccttctgc caaagggatt aaccgcaagt gctcgcgaat
     2161 ccctccaatc acaataccag atcctgaagc gtaagcatca gtttcaagaa cgatattcat
     2221 caaagtacct cgatcactcg tataaatcac tgtttcttga tcagggatct cgataaggtc
     2281 ttcataaaaa tacgggaaat tatttccatc ctgtgtaaaa cgaacttgag gataagataa
     2341 caattcttct ttggtgatct ctgcgtgttc agctaatgga tgtccttgcc ttaaaaaaat
     2401 atgcgttttg aattttccaa tgctgcggcc acttagctct ccttgttgta aatatcttct
     2461 gataccagct tgattatgct cattcatata aataatgccg atctcactgt gctgctcttt
     2521 gacttcttcg atcactctcg ctgttgtcgt ctccatgatc cgaaattgtt tgatctcgtc
     2581 tttgaattcc tcgagtagct gtgcggtcaa aggacctaag aaatcataat gctgggcagc
     2641 gatcgaaaaa ttgtctctct tttcactcgt tagatagtga gtttctaatg tatcaagctg
     2701 gaccaatatt ttctcggcac gatttaagaa gtcttgccct tcttctgtta aatatgcccc
     2761 tcgattcgtt cgagtaaaca gcgtgatccc taactcggtt tctaattctt tgataccagc
     2821 tgaaagactt ggctgggaga caaacatttt ctttgccgct tctctgaaac taccattgtt
     2881 tgctacagcg accacgtatt tcatctgctg aatattcatt gctcaaactc ctcgaaataa
     2941 taaatttctc ttccattcaa gggctggatt ggtcggttgt tcggtcgagc atactgacca
     3001 tcgaagggga gaagaaactc ttggttcagt tttcctacat gatccattac aaaccattgg
     3061 attggcccgc tggtaggcgg agttgtcaat gagccaatat aatggaaatg gcttttttgc
     3121 tccggaaaga acacatccgg atttacccaa tgctcatgtt tttctaagtt ccaactttcc
     3181 ccattttctt gattatacag ccaaccttcc tgtaccatta gctggtacat gacacccaca
     3241 actagattct cttttttgct gttcatatga acaaaatgaa attcaatatc ttcctgtttt
     3301 ccgttgatga tatgttcaga aggcaagtgg aaatgaatat ctgtcaaata atagcgttct
     3361 ttcttgaact ctacataact gagttggtca aaaggtacta aatgaatcgt gtttttgaat
     3421 tccttgtcag taaaccgttg cttttgataa tgaaaggaaa gcgtgtctcc ttctattttg
     3481 gtttcttccc ccttggtcaa atgaataggc gactgcaatg gaaattccgc acctctcgca
     3541 aaccaatcac ataaactcgc ccaattttcc ggacctttgt ctccagaata gccccattcg
     3601 acatccatat tctttttcaa ctatacttcc ccctgcatct catatcattt ttatttttct
     3661 tctttcttta caatcgttga gacggtttct aaaaacgcct cttttccata aaattcctgg
     3721 ttcaatagtt ccggaaatat ctctttaaag aaatactgaa cagaaggccg atgttcaaag
     3781 cttttaatcg tagtcactgc ctcaatgaac atctccttat aaactttttc cgggttattt
     3841 ttgatgattt catcaaaaga ttcataaaga aggtcaacct tatctgaaat ggctaatagt
     3901 tctccttcta cggtttcatc ttttccttcg aacaaccgac ggcgataaac ttcttggaac
     3961 tcagctggaa tctcttggtt gatgaattcg tccgtcatct tttcttcaac tgtttgcagc
     4021 atccctctta actctttgct tgcgtatttc accggcgttt tgatatcacc aataaaacgc
     4081 tctgtgtagt catgattcaa tgatttttca tagagcagtt tccaatcgat cggttgtcca
     4141 ttcgcttctt caatgtctcc tagaacttgc gcaatagatg ctacacgata cgaatgtgct
     4201 gcaactgtat gctctgtata tttaaaaaat ccaggtgccc ttgtgatcgt ctctaaattg
     4261 ttcaatccta aaataaattc attcaacccc ataaaagtta cctccctttg agatttcttt
     4321 ttccgaatat catatcatta aataactgat attcgcaaca tttccgctct ttaccatttt
     4381 tgaaacagct cccttaccaa aaaatagaga aaatctatat ataatagaaa aaagagaaga
     4441 gattattctc ttctttctgc taaccagtct tagaaaaatg aattttaaaa aaatcaaaaa
     4501 ctgatcacga tagaagtttc ttttcatacc tgatgaaaag atgcttctcg caatcagttt
     4561 ttggattttt gctattccaa ttgatgattc tggagacaca aatcggattt ctctatcttc
     4621 atcaagcgcg cttaaatctg ccaattttca ggatcttttt tccattcttt tagcagagtt
     4681 aattcttgct catcgatata acgatcttct aaagctgctt caatcaatac agaataattg
     4741 gtcaacgtca taagagggat ttcggctttt tcgaaatttg cttttccttt tggcaactca
     4801 tacgtaaaga tagccgcaac accaaggata tccgcacctt ctctttttgc tgcttcagct
     4861 gcttccaaga cacttccgcc tgtagaaatc aaatcctcga tcacaaccat cttctgacct
     4921 tcaaatatac gtccttcgat ttggttacct ttcccatgat ctttcgcctt acttcgaata
     4981 tagaccattg gcaaatccag tatttccgct acccatgcgg catgagggat tcctgctgtt
     5041 gcagttccag caatcacttg tacttcaggg taagcttctt tgattttgct tgctaatcct
     5101 tttgcgatct cttttcggac ttttggatag ctcatcgtga ttcggttatc acagtaaatt
     5161 gggcttttga ttccacttgc ccatgtaaaa ggattacttg gatttaaaaa tactgcttca
     5221 atttctaata agtcttttgc gatactttgt tcaacattca ttttaggtta gctccattct
     5281 gtttgaatcg tttgatatgc tttataagga ttagttgact gagtgattgg tcgacctata
     5341 acgataaaag ttgagccgat cttttttgcc tgagaaggtg tgactactct tgtctgatct
     5401 cctgcgactg ttccttctgg tcttataccc ggagttaagc aaacaaattc gtctcctgcc
     5461 atttctttga tcgcttctac ttcccaagca gaagaaacca caccatctaa tcctgctttt
     5521 ttggcacagc tagcataatg gatcacactt ttttctaaag aaacttcgat tagttgatcg
     5581 gcatgcattt cttcttcact tgtagaagta agctgagtga tagctagaag tagcggacgt
     5641 tttccacctt ctggagtccc ctcttctaat cctcgcattg ccgcctccat catacgaata
     5701 ccgccagcgg catgaacaca ggtgagatca acaccaagct ttgccaatcc ccgcattgct
     5761 ttttcgaccg tattcggaat atcgtgaagt ttcagatcta aaaatacatt atgaccagcc
     5821 tcttttagat aacgtacgat ttcaggtcct tcttggtaga acaattccat tccgattttc
     5881 acaaacaatt tttcttcttt cgggaaaaat cgaagaaagt cttctacctc ttgcctagtt
     5941 gaaaaatcta atgcaataat tggtcgttgg tctagttgat tcatcgttca cgttcctctc
     6001 tcacttcttt gattaatctt tccagcgatt cgatgcctag ttcgctcatt cgcacaggga
     6061 gctctttaat tagtttagga cagatatacg gatcggtgaa attcgcggtc cctatagcta
     6121 cagcacttgc tccagccata aacatctcaa gaacatcatc cactgtctgc acgccgccca
     6181 tcccaatgat tggaaggctg gatatacttg ctacttggtg aatcaaacga atagcgacag
     6241 gcttgattgc tggtccggag agtccacctg tttgattggc taaaatcggt tttcttgtct
     6301 taaggtcaat ccgcatacca agaagagtat tgatcatcgt aaacccatct gcccctccag
     6361 cttcgattgc ctgagcgatt ggaacgatgt ctgttacatt tggggacaat ttgacataga
     6421 caggaacaga agaaactttc tttactgctt gtgttaattg aaaagcaaca tcagaatctg
     6481 ttccaaaagc aattccgcca tgtttgacat ttgggcaaga aatgttcagc tcgattgctt
     6541 tcacatttgg tgcttcgcca attttgctac aaacttctac atagtcttct tcacaagcac
     6601 cagcaacatt tgcgatgatg ggtaactcat tgtactcctc taattctgga agaagtttat
     6661 gcataacaac gtctagacca ggattttgca aaccaattgc attcaacatg ccagatggtg
     6721 tttccgccac tcttggcgtg ggattgccaa agcgggcatt tggagtcgtt gccttgacca
     6781 tgatcgatcc aagctgattc aaatcatagt attttccgta ttctttgcca aaaccgaaac
     6841 agccgcttgc cggcatgata ggatttttta attctaggcc aggaagtttg accgctaaag
     6901 gattctcatt catataatta cctctcctat tttaaaaatc ggtccttcgt cacaaacttt
     6961 cacacttttt gttcctgttt catcttccgg cgtatgacaa acgcaagcat agcaagcccc
     7021 tatcccacat gccatgcggg attctaatga taactggaca ttttgatgcg aagaaaacag
     7081 ctgttccact gtcttcaata acccgtttga accacatgca aaaacagctg taggttccgt
     7141 cttcgttcct aacaataaat taccgacatt tccgtgcata ccgtatgttc catcgtcagt
     7201 agcgattctt gtttctccta gacgattaaa ttctttttca taataaacga cttcatgtgt
     7261 ggcaaaacct aaaaaatgcg ttggcttaat tcctttttcg actaactgtt ttgataactc
     7321 atatagagga gggacaccga ttcctccacc gattataaat acttcgtctc ctgtatgaag
     7381 attggacaaa tcaaaaccat tgcctaaagg acccatgaca tctaaatggt ctccggcaga
     7441 aagagtagag aagactctag tcccctcacc ttccacccga taaatgatac ggcaagtatt
     7501 tgtttcgtgg tcgatatgat tcaagctaat cggtcggcgt aatagcaagt ctgcacgcgg
     7561 cacgagaata tgcaagaact gtcctggttg ctgcatttct tttactagat cacctttcaa
     7621 tgtcatttca aaaatctttg gtgccagctg tttttgctga acgatttcca tcatttcttg
     7681 tttcatctgt cccctcctgc aacggttttt cgtctttttg tcttaacatg tgctcgccgt
     7741 taaatagggt tagttgaaaa agcacgggat tccatcactc gaacgatcgc atctgctgtg
     7801 tctaaagaag taaacaatgg aataccatgt tcaactgctt ctcttcggat gatgaaaccg
     7861 tctttagaag catttccccg atctttatca atcgtattga caaccacttg tgttttacca
     7921 tctcttatta agtcgactac atttttttct gctgcttcct cagaaatttt cgctactgtt
     7981 tcaacgacca gaccattttt ttcgaaataa gcagctgtat gtttcgttcc tatcagacta
     8041 tagccaattt ctgtaaaacg tttagctaat tctagtgctt cttcttttgt ttcgtccgca
     8101 atcgtaaata atacggctcc atattcaggc aagtgtaatc cagaagcttc gaatgccttg
     8161 tacaaagctt tgtctaattg tctgtcagat cccattactt ctccagtcga tttcatttca
     8221 ggccctaagt aagtatcaac tttctgcaat ttcgtaaaag aaaagacagg tgctttaaca
     8281 tgaacttctt ttgtttctgg ataaagtccg ttttcataac caagtgtctt tagtttctct
     8341 cccaaaatag ctttcgtcgc aatttgtgcc attggaattc ctgtcacctt acttaagaat
     8401 ggaacagtcc gacttgctcg aggattgact tcgatcacat aaacctcatt ttcatggatg
     8461 acaaactgga tattcatcat cccgacacaa ttcaaaccta atgctaagcg gatcgtgtaa
     8521 tcttcgatcg ttttcttgat cgattcagat aatgtttgag gtggatacac agccattgaa
     8581 tcccctgaat ggacaccagc acgctcaata tgctccatga tccctgggat gagtactgtt
     8641 tcaccgtcac aaatcgcatc cacttcgcat tcaccaccaa gcaagtaacg gtccactagt
     8701 actggatgtt ctggagatgc tttcacagca tgttccatgt aatcttctaa atctcgctgg
     8761 ttttcaacga tttccatcgc acgtccgcct aatacatagc ttggacgaac aagaactgga
     8821 taaccaattc tcgaagcgat aaccacggct tcttctttac ttgtagcagt atcccctaaa
     8881 ggttgaggaa tatccaactc tttcagcgct tgctcgaata aatcacgatt ttccgcacga
     8941 tccaagtctt cgatcgttgt ccctaagatt tttacaccag cagcagtcaa aggttcggct
     9001 aagttgattg ctgtctgacc accaaattga acgattactc ctatcggctg ttctagctcg
     9061 atcacattca tcacatcttc gaaggtcaat ggctcaaaat ataatttatc cgaaatagaa
     9121 aagtcagtcg aaactgtttc aggattgctg ttcatgatga ttgcttcgta tcctgcctgc
     9181 tggattgctt tgacagaatg cacagtcgca tagtcaaatt caaccccttg tccgatacgg
     9241 ataggaccag atcccagtac tagaattgag ggcttttctg atcgtgaact ttcattttca
     9301 tattcatagg aactataaaa ataaggtgtt tttgattcga attccgctgc acaagtgtca
     9361 accatcttat atacaggaat caaatcattt tcttttctca tctggcgaac ggcttcttcg
     9421 tttatttccc acagctccgc cacttttttg tctgtaaaac cgttttgttt cgctgttttc
     9481 aatatcttgt catccaacgg ctgctgtttc aactgctgtt cgatttctac gatatgcaac
     9541 agtttatcta aaaagaataa atcgattttt gtcaaatccg ctaattcttc tatggtgtac
     9601 cctcttctaa tagcttcagc tacataaaac aggcgatcat cttgtgctcg aaccactttt
     9661 tggattaggt catcgtccgt gatgtctgcc aactcaggaa gttcgatatg gtgtgtaccg
     9721 atttctaaag aacgcacagc tttcaataaa gactcttcga tattccgacc gatagccatc
     9781 acttcaccag ttgctttcat ctgcgtgcct aaaagccgtt ctccgttttc aaacttatca
     9841 aacggccagc gaggaatttt agctacaaca taatctaatg caggttcaaa ttctgcaaaa
     9901 gtcgttcctg taacaggatt tttcatttcg tctaatgtta atccaagcgc tattttagca
     9961 gctagcttag cgatcggata gccagtcgcc ttacttgcta acgcagatga acgagaaaca
    10021 cgcggattga cttcaatcac ataataatta aaactatgtg gatcaagagc gagttggaca
    10081 ttacagcctc cctcgatctt aagtgctcga ataatcgaaa gagaagcatc acgaagcatt
    10141 tgatattcat ggtcagacaa tgtttgacta ggggcaaata cgatagaatc acctgtatgg
    10201 atacccaccg ggtcaaaatt ttccatattg cagacaacga ttgcattatc agccgaatct
    10261 ctcatcactt catattcaat ttctttaaaa cctgcaatac ttcgttcaat caaacattgg
    10321 gtagcggggg aaagacttaa tccattttct gatacgatac gtaattcttc ttcattttca
    10381 cacatacctc caccagttcc gcctaaagta aaggctggac gaacgatgac aggatagccg
    10441 attttatttg caaaatctac agcttcttct actgtattga cgatttcaga ctcggggatt
    10501 ggctgattca attctttcat caactgtttg aatagatcac gatcttctgc ttgatcgatc
    10561 gcagaaagct ttgttcctag aagttctatg ttcaattctt ctaaaatacc tgatgctgcc
    10621 agctccattg ccatattgag gcctgtctgt ccgcctaaag ttggaaggag agcatctgga
    10681 cgctcttttc gaagaatcct tgatacaaat tcaagtgtga tcggttcgat atatacttga
    10741 tctgccactt ctttatccgt catgatcgtc gcaggattag aatttactaa aaccacttca
    10801 tatccttctt cttttaaggc aaggcaggct tgtgttcctg cgtagtcaaa ttctgcggct
    10861 tgaccaatga tgatcggacc agatccaatc accataattt tcttgatatc tgtacgtttc
    10921 ggcatctgtt tactgctcct ttcctgcgtc catcatttcc ataaattcat caaataaatg
    10981 tagtgcatca tgcggaccag gggcagcatc tggatgaaac tgcacactga aagcgggata
    11041 atctctgtgt ttgactcctt ctactgttcc gtcatttact tctacatgag ttacgatgag
    11101 tttttctgga tcaatcgtgg cttcatcgac tgcatagcca tgattttgag aagtaaaatc
    11161 aattcttccg gtcgctactt ctcgtaccgg gtgatttaat cctcgatgtc cgaatttcat
    11221 tttataggta tctgcaccgt tggctaaagc aaataactgg tgaccgagac aaataccaaa
    11281 aatcggtact tttccttgga tttttttgat catttcgatt gcttctggca catcttttgg
    11341 atcaccaggt ccattcgtca gcatgactcc gtctggtgat agcgctaaaa tcgtctcggc
    11401 atctgtgtta tagggaagta ctgtgaggtt acagtttctt ttactcaatt ctcgtaaaat
    11461 actatgtttc aagccgaagt caatgacaat gactttccga cctgttcctg gacttggata
    11521 aggtttgtta gttgagactt gctgcacttg attggttgct agaacggttg ctttcagctg
    11581 atcaaatgca tgttcgaagg aatctccagc atcaactata ctagctttca tcgttccgac
    11641 ttcacggatt ttgcgagtaa gggcgcgcgt atcgatacct gatattccag gaattccttt
    11701 ttgtttcaaa aatgaatcta gcgtcatttg gtttcgccag tttgaagcta cacgtgcatg
    11761 ttcttttact actactcctt tgcatgttgg agaaatcgat tcataatcat ctctatttac
    11821 cccataatta cccaccatag gataggtaaa tgtaatgatt tgaccgttaa aactttgatc
    11881 agtgatagtt tcttgataac cagtcatact tgttgtaaaa acgatttctc cgaagacact
    11941 agcatctgca ccaaaagcct ttccttcgaa aactgttcca tcttctaata taagcaaacg
    12001 ttccatactt ttattctccc ttctgccaca caagttttcc gttgacaaaa gtcatttgtg
    12061 tttcgccttt tactttccag ccgataaaag gtgtattctc cccttttgat aaaaagtctt
    12121 ctttatcgat cgtgcaagtt tgtgtaatat caaaaactgc tacatcagcg ggggcaccaa
    12181 ccgttagcgt tcctgcattc aaaccaaaaa tctcagccgg tttaactgcc aaccaattga
    12241 tcacttgttc caacgtgaat cgaccagttt ctacaaaatg agtatagatc agttgaaacg
    12301 ctgtttcgct tcctacgata ccaaatggtg atttcatgaa actttggctt ttttcttcta
    12361 atccatgggg ggcatggtct gtagcgatgc aatcgatcgt accgtcaagc aagccttcga
    12421 tcaaagcttc tctgtcctcc cgtcctctta gcggcgggtt cattttccaa aagccgaaat
    12481 cttcgggaat atcttcgtcg atcaaaataa gatgatgggg tgaaacttct gctgttacgt
    12541 ggattcctgc tttttttgcg tctctgatta cacggacact ttctttagta gaaacatggc
    12601 aaacatggta atgaacacca gttgcttcag ctagcaacag atctctagca atttgagaag
    12661 actcggttac gcttaagatc ccgggaagac caagttcttc tgccttcttg ccagcgtgca
    12721 taacgccgcc aaataataaa gattcatctt ctgtatgggc tactagggct ttattgtttt
    12781 ttgcagcttc tttcatagcc agatacatcg tcccagctgt ttggacacct acaccgtcat
    12841 ttgtgaaagc aaaagcacct tcttcaatca gtgcttcttg atcaactaat ttctcacttc
    12901 gcagattttc tgtgattggc gcatactgca ataccttcac aactgcatct tttctaatga
    12961 tgtcatatac ttgtctcagc ttttctgccg tatcaggtac aggatttaaa ttcggcatcg
    13021 cgcatacagt agtgaaaccg ccacgagcag ctgagcgagt cccagcttcg atcgtctcct
    13081 tgtatgtaaa tcctggctct ctcaaatgaa catggacgtc cactaaacca ggtgtgatca
    13141 attgtccctt tgcatcaaac acttcatcaa attcggcttc tgagaatcct gtaccgattg
    13201 ctttgattcg cccatcttct atccaaattt ctgctggtgt cgtcatattt tttcgtgtat
    13261 tgatctgacc gtttttaatg agtgttttca ttttttcatc ctcctataat tacgcttttc
    13321 catttagcac tgcttctaag attgccattc tgacgaatac tccattgctc atttgctgaa
    13381 cgatccgcga ctgtaatcct tccactaatg aatcagctaa ttctacatca cggttaactg
    13441 gtgctgggtg cataatgatt gcatgttttt gcaacttctt cgcacgctca actgttaacc
    13501 catgttcctg atggtagcct tcttttgaga aactttcttt tccatcatgg cgttcgtgtt
    13561 gcacccgaag catcatcatg acatcaactt gatctagtag ttcatccaat ggcatataat
    13621 gtccgtacac ttcgaattca tcgtcgtacc attctctagg acctgagaag aatacttgtg
    13681 cgcctagacg ttttaacatc tgcatattgg atttagctac gcgagagtga gtgatatcac
    13741 ctacgatggc aactttcaga ccttcaaaat gaccaaattc ttcataaatg gtcatcaaat
    13801 caagcaagca ttgggttgga tgctgtccgc ttccgtctcc tccattgata atcgaacact
    13861 ggattgtttt actttgtatc agttcgtcat aatagttctc atcaccatga cggataaccg
    13921 ctacgtctac gcctaatgct gacatcgtca gtactgtatc gtatagtgtt tccccttttt
    13981 ggacagagct tgtgcttgct tcaaattcaa tcacttctag ccctagtttt ttctccgcta
    14041 catcgaagct tttatgtgtg cgagtactat tttcgaaaaa gaggtttgta gcaaagtact
    14101 ggcgcttttg cggagtccaa ttagcacctt gcttgaattc ctgccctctg cggatcaagc
    14161 ccataacttc ttgatcagta agtgcctcaa cggtcaataa atgctttaag ctgatacgtt
    14221 ctgatttgat gatcataatg tttcctcctt agttttcttc gcttcgtgaa gtttctggta
    14281 agataagatt taaaatgatg ccaagtacag ttgctaatgc cattgccgac aatgtaaatg
    14341 tgcctacttc aaagacgagt ccgccaattc ctactactaa gataactgaa gcaatcaaca
    14401 gatttttctt tttatcaaaa tcgattttgt tctcgattaa aatcttcatt ccacttgcgg
    14461 caattactcc aaataagata aaactgattc ctgagatgac tggtccaggg atacttaaaa
    14521 tcaaagcgct taattttcct acgaatccta aaatgactgc aaatactgca gctccaccga
    14581 tcacaaacac gctatggaca cgtgtgatag ccagaacacc aatgttttca ccgtaacttg
    14641 ttacaggagg acctccgaca aaggctgcca cgatttgtgc taatccatca cctgtcaacg
    14701 tcttatgaag acccggttct tcaaagaaat tacgtttagt tagtttattc aataccataa
    14761 gatggccgat atgctctgtc atcgtcacaa aagcgatggg tgccattgtt gtgattgctc
    14821 caagatatag ctttggttca tattgtacaa agggaatctc aaagttagga acagcaaacc
    14881 aggcagcgtc tacgattggc ttagtatcca cgattccaaa cagcaaggct acgatgtatc
    14941 cgctaataat acctagtaaa atcggaatca atccgagaaa acctcttagc cacatgttga
    15001 agaaaattgt taatcctaat gtgatcagcg ctacagcaat atacttgaaa tcatacgtgc
    15061 cctgattata catagcattt gttgctgcat ttgccgcaag tcccaacccg ataaccatga
    15121 tgactggacc gacgacgatt ggaggcaaga ttttatccag ccatgctgaa ccgatctttt
    15181 tgatgatcag cgcaacaatc aaatagacta atccagttgt gactgctcct tgtgcaatcg
    15241 ctggataacc atctgttttc atcaaaagct gcatcgctgc aatgaaagcg aagctgcttc
    15301 ctaagtacgc aggtatcttt cctttagtag taaataagta caccaatgta cctagtcctg
    15361 aactgactag cgcaatacct ggatcgatac ctactaagat ggggactaac acggttgctc
    15421 cgaacatcgt gaacaagtgt tgtaaactta atcctaccca atgtcctggg gttgggcgat
    15481 cgtggatatc taacaccacg tcatcattat gaaatccttt tttctccgac atgtttctct
    15541 ctcctctaat cttcctcttt caaaatcatg atgcgatctt gtccatcaag ctcttgcatc
    15601 tctactaaaa tctcttccgc ccgagatgtt ggaatgttct tcccaacata atctgcacgg
    15661 attggcaatt ctcgatgccc acgatcgacc aggactgcta atgaaatttt tcttggtctg
    15721 ccaaaatcca ttactgcgtc cattgctgct cgaatcgttc gtcctgtata caaaacatca
    15781 tcaatcaaaa taacttcttt tccttctaag gaaactggga tgtcagaaga atgaagttcc
    15841 ggttcttctg gattttcttt tttgtcatct cggtataaag tgatatccag ttctcctaca
    15901 ggaatatcga tatcttctag ctgcttcagg cgttcggcaa ttcttgatgc aatgtagatt
    15961 cctcgtgttt tgatacctac caatacgata tcttggatac tatggtttct ctcgataatc
    16021 tcataagtaa ttcgagtcaa tgctcgcttc atggttacct gatctactac ttcttttgct
    16081 tgcattttca ttccccctac ttttttgcat aaaaaaactc ctgccctaag aggacaggag
    16141 gaatgtttag actgagcgta tactgataca ctgatagcta tactatgtca atgagcaatc
    16201 tacttatggc gcaccatacg tatccttgct cccacccttc ttagcctcac gggactaaac
    16261 ttaaaggaat tctattaagt tttatgcttt cgttgttaat tactataccg ttatctaaat
    16321 taaaatgcaa tgttttttct taatttttct aaagtttttt caaaaacttc tggaagaggt
    16381 gcttcaaaga tcatcttttc gtttgtagtc gggtgcgtaa aacctaacat ttgcgcatgg
    16441 agaaactgac cattgccttt caaagttttc ttcggtccgt atactggatc tccagctaac
    16501 ggataaccga tatacttcat atgcacacgg atctggtgtg ttcttccggt ttctagtttt
    16561 aattcaacca gagtaaatcc ttcgaaacgt tccaatacag taaaatgtgt gacagccgac
    16621 ttcccatctt ctcttatcgc ctgcattttc cggttttcct tcgaacggcc gattggcgca
    16681 ttgatggttc ctttttcgtg aggaatctct ccatggacta aagcaacata tttgcgcaaa
    16741 gaggtcttat cttttaattg ctgagctaat gattcgtgtg cctggtcatt tttggcaacc
    16801 attagcagtc cggaagtatc tttgtcgatt cggtgaacaa tacctggacg aataacgccg
    16861 ttgatcgtag aaagatcctt gatatggtac atcagcgcat tgaccattgt gccatgcgta
    16921 tgacctgctg aaggatgaac gaccattcct tgaggtttgt ttatcaccgc tacatcttca
    16981 tcttcgtaaa cgatcgtcaa cgggatattt tctgggacca catctaatgt ttctggttcg
    17041 gggatcaaga cagtaatctc gtctccttgt tttactttgt aatttgcttt gactggctgt
    17101 ccattgacag aaaccgctcc atttttcagc cacagctgaa tttgcgaacg actgtaatcg
    17161 gtgaataaat tagtcaatac tttatcgatc ctaccagatt catggtgaat cgtcgtttta
    17221 agttctgtca tttttttctt tgatcctttt catctaaaat aatataaatt aacatacaaa
    17281 tcactccaca tacaagtgtc acatctgcta cgttaaaaat cggaaagctc ataaaatctg
    17341 tctggaacat atctactaca tagccaagac gaatacggtc gataaaattg ccaatcgcac
    17401 cagctagaat caaactcaat ccaatcatga accagcgatt acctttttca cgatttttaa
    17461 tcatcaatgt gagaatcaca acgactgcaa tgagtgtcac tatagtaaag aaccacatct
    17521 tcccttctag catactccat gcggctccag tgtttcgaat atgattcagt gacaaaatac
    17581 ctggtataag atttttcgtc tctccaagcg ctagattatc agtgatccac catttgacca
    17641 actgatccac tcctactagc aaagcgctga atatccaata aataattaac aaaaaatcaa
    17701 tccttttcta tttgtttata aatatcacga ggtcgtacga tcccgagcag attaccatcg
    17761 ggattcccat ctttagtgat aagtacggct tccaaagtcc cttgctcacg aaacatcgct
    17821 tcaacctcgt aaatatgtgt tttagctgga acaaaatgat aatttgtgta ctttccgttt
    17881 tggatgatca aatccaacgc tcgtttattt gttaaatcaa ccggaccttt ttggctttct
    17941 tttgctagcc aaaacccgat attacgtaaa gtaatcaatg ctacaaattt tcctttattg
    18001 tataacggaa attgtgaata ccttttttct gctactatct ttaacagttc aagtaacgga
    18061 agatcttgtt caaaacctgt tacacgtttt gcaaatcgag gcagcacggt ttcaggctga
    18121 atcagttctt gttcgatcag ctggattcgc ttgactgtcc aatcatttgg ctctgcaatg
    18181 acaaaatcga ctgcgatccg atcatggacg atcgcattcc ttaactgagc aagctgtaaa
    18241 agatcatctt cgtattttct gatcattaat tgttttcttt gagctaggcg tctgacaagt
    18301 tcggtaaatc ccatatttcg tgcatttccc atctcgtctc tcatccattt ttcgattcga
    18361 ttgaaactga ttaaaaaaag atcagagttt gccataattt tcctccttga tcaaatatgc
    18421 ccggtttttt atatagaaaa agaacgcaat caacacaata actgcaaaaa aactgaaaaa
    18481 taaattttgt aggaaaacgg cccccaaccc agttgctaga aataaaaacg gatagatttg
    18541 aagaatcaag taattcattg tgatcacata agcaggcttt gcttctttca ctgtataaac
    18601 ggggcttttt agccaataaa aggtgacctg catcgtaaag ggcacttcca gatcaagcgt
    18661 tatcttttgt tcatgactga gaacactgcg tttttcattg ttgattctta gctgaatcga
    18721 gctacccata ccgtaaaaac cggtttttct tataaatgtc gttttcatca taccctccta
    18781 ttatgcttta gtatagctca aaatacaata aagaaaaaga atgatcctag tgtaaacaaa
    18841 attaattccc tatcgtctaa aaaaagaagc tgtagtcaaa atacagctcc ttcgatggta
    18901 gattataatc aagcttaaaa caatcccaac acttctccgt catttgtcac gtccatattc
    18961 aatgcagcag gttttttagg caaaccaggc atcgtcataa catctccagt caaggctact
    19021 aaaaatcctg cccctaattt tgggatgatt tcgcggatcg tgatggtgaa atcttccggt
    19081 gcacctagca gtgaaggatc atcagaaaat gaatactgtg tttttgccat acaaatcggc
    19141 agtttgtccc atccattctt cgtaaactct tctatttgtt tttgcgcttt tttgctgaaa
    19201 acaacaccat ttcctccgta aattttcttg acgattgttt ctgtcttttc ttgtatcgtt
    19261 tcttctaggc ggtataatgg cttgtaatta gcttcttttc tatcaatcaa tcgtactaca
    19321 gcttttgcta aatcaacgcc gccttctgct ccatctgccc atacactcgc tctcttggca
    19381 agaatcccct gattttcaca caagtgctcc aacagtgtga gttcattgtc tgtatctgtt
    19441 acgaattcat tgattgcgac gatcacaggt agctgatatt gttccatatt acgtatatgg
    19501 cgctttaaat ttgcaaaacc tactttcaaa gcatcaagat tctcattttt aagttcatct
    19561 tttttcattc cgccatgcat tttcaatgca cggacagtgg cgacaatcac cacagcatcc
    19621 ggcgcttttt tcaagttagg tactttgata tctaaaaatt tctctccgcc aagatctgca
    19681 ccaaatcctg cctctgtgac aacgtaatct gctaatctca atgctgtctt ggtagctaaa
    19741 atactattgc agccatgagc gatattggca aacggtcccc cgtggacaaa agctggtgtt
    19801 ccgtaaattg tttgtacaag attcggcttg attgcatctt tcagcagtaa tgccagagcg
    19861 ccttctgctt tcaagtctcc agcagtcaca ggctgacggt caaatgtata gccgacaacg
    19921 atccttgcaa gacgagcctt taaatcttca aggtctgccg caagacacaa gatagccatg
    19981 atttcgctgg caactgtgat atcaaaccca tcttctcttg gaacaccttg gattggccca
    20041 cccaagccaa caattacttt acgcagttca cgatcattga gatcgactac ccgtttccaa
    20101 atcactcggc gggcatcgat gttcaattca tttccttgat gaatatgatt atctaaaaga
    20161 gcagataatg cattattagc tgttgtgata gcatgcatgt caccagtaaa atgcaagttg
    20221 atatcttcca taggcaatac ctgtgcatat cctccgcctg cagcaccacc tttgattccc
    20281 atcacaggac caagtgaggg ttctcgcaat gcaataacag attttttatt gattttattg
    20341 agcgcgtctc ctaaccctac agtgatcgtt gactttcctt cgccagctgg tgttggattg
    20401 atggaagtaa ctaagatcaa atgcccctca gcgttatcct ttgatcgatt gattccagaa
    20461 aaattgattt tcgccttata tttcccatac agttccaaat cgtcttcctt aagatctaat
    20521 ttactagcca cttcaacaat cggttctagc tctgtttctt gtgaaatttg cagatcattc
    20581 ttcatttgat tacccctttt cacgaacttt attcaacaaa atatcttctt tgttaagata
    20641 tgccaattat accttttttt attcagaaaa aaaacataaa attacaggtt tttaatttat
    20701 ttgacgtact tataaatact ctttataatg aaggctatga tcagacttta gaaaggtcgt
    20761 gagtgctttg accacaggaa ttgtaaaatg gtttgacaac aaaaaaggat acggctttat
    20821 cagttatgat gacacagaag aaatttttgt acattttact gcgattgaag aagagggatt
    20881 caaaactttg gaagaaaatc aagtggtcga atttgagatc atcgaaggga atcgaggaac
    20941 acaagctgcc catgtcaaga aaggcaacgt tcagactacc gatactagta tgcatgaata
    21001 gataaacaaa tagagtgaga cgctaaacgg gatgaaccgt acgtctcact cttttctttt
    21061 cctgtaaaaa ttcgtttttt taggttctga tttttaaaat tagctttttc tttttttcgt
    21121 ataaggataa ggaattgatt ctgatttggg tccgtttttt tcaaaatgat caaaaaggac
    21181 tacttgatct ttttttcgca tcatgaaaac agatggggct ttctcatctt gcaacatcat
    21241 ttgcacccca gtattagttg gcgtcaaaga tcgaatctgt ccgacagata tttctcggtc
    21301 tttccaaaaa gcagcataac gtataatcac agagtttgat tttaaaataa aagaacgccg
    21361 caaacctaga aatagaaaaa caagaaaaat acctaaaaca aaattgcttt tccaataagg
    21421 acctgtgttt tctaaagaaa gaatcagact aaaaaacaga atgatcaagg tcaatgacca
    21481 atagatgatc gtatgtgcca gttcaggctg ccatcgaata ttttttttca ttctctaacc
    21541 tctcaccgat tcagtaatga tataatctta ccataacatt agtttgaaca aaaaggagaa
    21601 tctcttttta tgttaaaagt atacattgat gcctctacaa aaggcaaccc tggtcctagt
    21661 ggaggtggaa tcttgattgt ctatcaaggt aaacaagaac agctatctat cccgctttct
    21721 atagggacaa accatcaagc agagttcgaa gtctttttaa aaactttaga atttctaaag
    21781 aaaaacgact tacagaatga aacgattttc tgtttttcag acagcaaaac actagtttct
    21841 acggtcgaca aaaacgcaac gaagaacgag ctcttccttc cctaccttca aagaatccaa
    21901 gaacttctat ccgaattttc tttattgatc ctgcaatggt tgcccgaaaa caaaaataaa
    21961 ggagcagata atcttgcacg tcaggctctc cataaacaat taaaagaaaa aaagactctt
    22021 taaattaaaa actttaagga gtctttttat agtttctcat ttaatataaa agataattgt
    22081 gatcaaacgt aatttccaat tggtaatctc cgattttttc ttctatttga ctacgtaaga
    22141 ttctttctag ttctgtatca acaaactgga atttctcagg gaccactaca tcaaattgca
    22201 gcgtttttcc ttgatgaatt actctaaaat catgaatatt aagccctgta cctgtttcaa
    22261 gaagaatttg ctttaactgc cgcaagatat tatagtattt ttcgttatca acaggcattg
    22321 gatccaagtg acagacaagt tccacatcca aagacttttt aaagtctttt tctatcagat
    22381 caataatctt atgagccaca ttcaaattca ttgattcatc tacttcgatg tggactgatg
    22441 caaagcgttt attgggtcca tagttatgca ccaataaatc atgatagcca agtatatcat
    22501 cgcaagcatt taaatgctct tccatttctt caatctctgc tggcgttggg cgacttccta
    22561 atagttcgta tacaaaattt cgaagcatcg tcaatccact ataaaggata tataatgcta
    22621 aagcaaaacc tatatatcca tcaatacgcc atccagttac ccattcgatt gctgctgaaa
    22681 gcaatacagc cagtgtagta aagacatcat tataactatc tgttgctgta gctctcaatg
    22741 tttcagaatc aatggattgc gcaataacct gatacatttt gccttgtgca aatttcaaaa
    22801 agatggaaat gattaggaca aaaaagacga tgggtgttaa agagacattt tctggatgga
    22861 tgattttttc agcagaagac tctaaaaatt gaaatcctac ataagtaatg atgatcgaaa
    22921 caaataaccc actgatatat tcgaagcgtt cgtgtccata aggatgttcc tgatctgctg
    22981 gctttgcagc aattttaaat ccgatcaaag tcaatatgga tgaagcagta tctgatagac
    23041 tgttcactgc atcagccata atggagacac ttcctgaaaa aagcccgatc attagcttag
    23101 agacaaacaa gatcagattc gtaaccaatc ctaagatacc cgctagtact cctttttttg
    23161 tccgctgttg cggtatttgt ttcttttttt cttcttgttt cttagccaag ttttttaccc
    23221 cttctagttt gcttgttgct caggtaaaaa gatggagagg acgattgttt tcctctcctc
    23281 tcttcctttt tctatctatc gtgcgtccta ttactattaa aagatggtca ttattctggt
    23341 ttcaacggtg ttgctgcaaa taacgctttt gctagtaatg gtgttatgat tcccgcacct
    23401 attgcttctg gtatcccatt gattgctgca acccctgcta aggttttaaa taaaagagca
    23461 gagtctacac cataggcatc tgccgttgca cctgtataaa ataatcccat gaatcctaac
    23521 actaagactg tattgaccaa tgaacccagt acccctgcaa aggctgagct gatcgttatt
    23581 gatttatttt tttgataaat ccagtggaaa accaagcctg ctactaagcc aacaagtact
    23641 ctgggaacta ccgagataat cggattcgtg aacactaatg tatcaaatgg cgttgttggc
    23701 atggcatagg cacgaacaat tgtagcgatt ccccaaaaca agccaatcac catgccatct
    23761 tttgggccta atactactgc agcaataatt actgtgatat ggataattgt taaactaatg
    23821 aatcctaatg gaataaaccc cagccaagga accatcgctt gtacgatgat gattgctaac
    23881 aagatcgcac gtaagactag tcgaaaggtc ttatttctac tattcatttt ttcacccctt
    23941 tttatttata ctaatcgtaa aaatttctgt cactttcgtc aactaaagac catccgaatc
    24001 cgaccatttg attagatgcg ccatccaatt gaaaaaagta tgagggcaag acttgtttgt
    24061 cttcgccccc ataatcatgt ttcgttcaat gtttgaactt ttgtttttct gtcaaacgta
    24121 aacgccctat tgttgcgcaa cccattcttt cgcagcttta agtgcatctg gaataccagc
    24181 aggatttttc ccgccagctt gtgccatgtc tggacgtcca ccaccgccac cgcctacttt
    24241 cggtgcgatt gctttaatca agtcgccagc ttttagtcca gcttcatttg attctttcgt
    24301 cattgccgct agcagactga cttttccttc ttgttcgttt gctaaaacaa gaatatctga
    24361 aatatttttt tgtttccatt ggtcagctaa ttgacgcagc tgattcatat ctttcacttt
    24421 tacttgtgct gcaatgattg tttttccatt gatcgtttct ggatctttga atacatcacc
    24481 agcttgttga ttcgctaact tgctagctaa ttgttcattt tccttttgta gctctcttac
    24541 ttgctgttgc aattgttccg cttttgaaac aacttctttc aattgaggtg atttaacaat
    24601 tgttgctact tgttttagtt gtttttcttc ttcttcaagt agttcgtacg cttctttact
    24661 tgttacagcc tcgattcgtc gcacgcctgc accaattcct gattcagaaa cgattttgaa
    24721 gattccgatg ttttctgtat ttgctacatg tgtgcctccg cacagttcga ttgaccagcc
    24781 gccaatattt actactcgaa cgtcatgtcc gtatttttca ccaaacaaag ccattgcacc
    24841 catgtttttg gctgtatcga tatctgtttc aattgtttca actgggatag cttcccagat
    24901 tttttcgttg acgattcttt ccatttcagc taattcatct gaagtgattt gaccaaagtg
    24961 ggtaaagtcg aatcgtaaat gtccaggagc gactaaagaa ccagcttgat ttgcatgctc
    25021 gccaagtact tctttcaatg ccttgtgcag tagatgggtt gctgtatggt ttttgatgat
    25081 ccgattgcgc atcgattgat cgatcaatag atgataggtt tgtccttcac tcattggtgc
    25141 ttttacttct acggtgtgca taaattgacc attaggcgct ttttgaacat ctgtaacaac
    25201 tgctacgatt tcgcctactt cattcatgat ccatccttga tccgctactt gcccacccat
    25261 ttctgcatag aaaggtgttt gatcaaagat catttgagct tcaccttctg cgacttcatt
    25321 caaaagagac tcacctttaa cgatgaccaa taattgacta tctgattctt gttctgtgta
    25381 tccaatgaat ttactttcta ctttgatatc tgtcaataaa gcagattgta cccccattga
    25441 tttttcagta ctgcgggcag agcgagcacg ttcgcgttgt gcatccattt ctttttcaaa
    25501 accagcatga tcaactttca gtccttcatc ttctgccacc tcttccgtta attctaccgg
    25561 gaagccatat gtgtcgtata gtttgaagat gtcttttcct gctagagtcg tcccgttttc
    25621 gttttttact tcttggatca cttgatttaa gatttccaaa ccttcattga ttgtttcatt
    25681 gaaacgttct tcttctgtac ggataacttt ttcaataaat tctttttgtt gaagtacttc
    25741 aggataataa cttaccatga tttccccaac aacagggact aaacgatata agaatgcttg
    25801 ttcaatacct aattttttcc catgcatgac agcacgacga agcaaacggc gtaagacata
    25861 ccctctccct tcattcgatg gcaatgcacc gtcgccaata gcaaatgaaa gggcgcgaat
    25921 atgatctgcg attactttgt aagaaatatc tgttactggg ttttcaccat attttacttg
    25981 tttgcttagc ttttctacgg cgtggataat aggcataaac aagtctgtct caaagttcgt
    26041 tgacgcatct tgaacgattg agaccatgcg ttccaatccc atccccgtat caatgttttt
    26101 atgaggaagt ggttcaaatg tgttatcagg cttatggttg aattctgaaa atactaagtt
    26161 ccagatttct aaataacgtt cattttctcc tcctggatag ttttcaggat cgtcttctgc
    26221 taaatcgtta taagcttctc cacggtcata gaaaatttcc gtatccggac cacatgggcc
    26281 tgcaccgata tcccagaagt tgtcttctac atcaataatg tgatctagtg gcaggccaac
    26341 ttcttcatgc cagatgcgtt ttgcttctgt atcttttgga taaactgtta cataaagttt
    26401 ttctggatcg aatgccatcc attttggatc agtcaaaaat tcccatgccc agtggatggc
    26461 ttcatttttg aaatagtcac caatcgaaaa attacccagc atctcaaaca tcgtatggtg
    26521 ccgtgctgtt ttaccgacat tttcgatatc atttgttcga atagattttt gggcatttgt
    26581 gattcttgga ttttctggca caactgaacc atcaaaatat tttttcaatg ttgcaacacc
    26641 agagttgatc cacaataagg ttggatcgtt cacggggatc aaagacgcac taggttcaat
    26701 cgtatgtcct ttagattgga agaaatcaag aaacatttgt cgaacttgtg cactacttaa
    26761 ttgtttcatg tcattacctg ctttctataa attaaataca aaaaaacacc atcacagcca
    26821 aggacgaaaa ctcgcggtac caccttgatt gcaatgatgt gtaatcatta cctcttaaac
    26881 tcgataacgc tgagctgcgt cggtatttct accaaaatag aaaaagggag caatttgatt
    26941 agtgactatt cttttttcag ccaagaaaga attttctgtg agtcttaaaa aacaaatcat
    27001 atccttttcg tacttaatta gtatacgcat tctattgatc actgtcaata tctcaatttt
    27061 tattttcatt tccttttggt catactccac gatttttggt acgataagaa taaaggaatc
    27121 aatacatctc tgctattcat gacaaggagg aatatgatga aaaaaatagt tggagcggat
    27181 gaatggatac gcgcagctag ctgctttttg agatatcaag tttttgtatt agaacaaggg
    27241 attcctgcag aactagaatt cgacggaaaa gatatcccgc aacaaaccta ttatctattt
    27301 cttgatcaaa aaagaccagt agctactttg cgttatgaaa agaaaacacc tacttgcttc
    27361 aagccggaac gattttgcgt agcaaaagaa taccgaggaa aagggttagg cggtcagttg
    27421 cttgaagctg ctgaaaaacg ggcggtttca gaaggttgtc agactagtta tgtagtagct
    27481 gaaatgacgg ctgtagattt ttatgaaaaa caagggtatc atacttgcac agaacctttt
    27541 attgaagatg aagtactttg tatcggaatg aaaaaaagtc tagcttaaaa acaagagatt
    27601 gtgacacgcc ttttgtcaca acctcttgtt ttttatttat gtgaattttt cttattttta
    27661 cgagcagtac ggctttgctg tctgcgttcg attttgcgtt cttttttatt tttttctgca
    27721 attgcccaat cgattttttt cttataacca ggcttgatct ttttcttttt cttcttcaca
    27781 agaccaatca gcgtgggatc taatacatct tttgattttt ctcgtttggc acgtctatta
    27841 cgatcgtatg ttttgacgat ttccccgttt ttgatttctt ttggttcaaa tgagacgccc
    27901 aatttttcta tcgcatcaat ggcttgctca tcatttggcg aatataacgt aatggccgtt
    27961 ccttttaagc cattacgtcc agtacgtccg acacgatgga taaagaagtc tagatcttct
    28021 ggaatttctg cattaataac atgagagaca ccttcgatat cgatccctct agcagctaaa
    28081 tcagtcgcta caacatattg atactccaga ttctgtactt gtcgcatcac tcgttttctc
    28141 tctcttgggg tgatgtctcc atgaatcttt gctactttca agccttggtt tttcaagtaa
    28201 tcggcaattt catccacatg ctgttttgta ttggcaaata cgattgctaa ataaggatga
    28261 ccaattgtca gcagttgata aatcatttga ttctcatctt taccttttgt tgaaatcagc
    28321 caattttcaa tgtcttcaga aataactgct tttggtttga tttcttcaat gattggattt
    28381 tccatgtatt ttcgtaagaa tggacgaagt ttttctggaa tagtggcaga aaaaactaaa
    28441 aactgcagct tttctggtaa tcgacttgca atttggtcta cttcatttaa aaaacccata
    28501 tccaatgtca tatccgcttc atcgacaaca aatgcaaatg cggtgtgaat cttcagcgct
    28561 tgttcattca tcatgtctaa tattctacca ggcgtgccta ctacaacctg tggctgttgg
    28621 tgatgcagac gatttaattg acgctgtttg tctgtaccgc cgacaaaatt cgagacacgg
    28681 atctccggtg tagaaaattt agcgatttgt gtagctgctt catagatctg tgcagctagt
    28741 tccctacttg gagctgtaat aacaacttgt acttcctctt tttctgcatt gattttttca
    28801 aacaaaggca acaaaaacgt atgtgttttt cctgtaccag tttgagattg cccaatgata
    28861 ttttttcctt ttgcaattaa aggaatcaaa cgttcctgga cctctgtggg ctgtttgaag
    28921 ccctttgcgg ttaacgcttc attgataaac ggtttgaagc ggaatatatc aaaattattc
    28981 attcgtgcac ctcttctctt taaattatca cgactttggc attataacac agacaaagcg
    29041 tttttgctca gctaatttcg agaatcatca tcctttgttt ggccaatcgt gctaacagta
    29101 tatgtgtgac tagctttttc ataaaacaga atccgttttt ttctcaaaaa tgatagcaag
    29161 atatttaaaa taaaaatacc ttgtagtaac aagacaccga gagaaatgaa tactgcactc
    29221 atctgcaaca ccgtattcgt tgtcgaattc atgatttgct gaagcaactg ccccaaccag
    29281 cttaaaccat aaaaaagaaa gtacagatac ccgtagcgga tcatcaatgc ttttaaagaa
    29341 attcgttcgc ggtcttcttc caccaaacgg atacgcacaa tttttttgcc aagtgtccat
    29401 ccattggtta taaacggtac aatcataaag tataccccta cttctaataa aagccaccag
    29461 atatgagaag taactgcccc tgaatcgaac gcaattttaa agaaaatcgc cgctaccaaa
    29521 ttaataagag ataaaaatgt ccagtcgatc aaataagcga ccaagcgtcg agtcaatgag
    29581 acagtctttc ctttttcata agaaagttca tccattcgtc ttcttgtagg aagcataaat
    29641 gtaaataacg gcgtaacgac aaaaccaatg attccaccca atgtatttgt cactaaatca
    29701 ttcacatcaa ataagcggta tggtcttggg tagataaaat aaagtccact tagctgcgtc
    29761 aattcaaaaa atagagaaag gcagaaacta gcaatcatcg ttttcataaa agaaagccgg
    29821 aaataatatc ttaaataaat gccaaacggt atgagtaata aaacattaaa agctggttcc
    29881 aaaaatacac tctgcttcat tgccggcagg taggtactag gttcagacaa gaccaatacc
    29941 gtgttgtctc tgaaatgttg ccatgaagca aataaatgca gctccatctt tggccctgtc
    30001 atttgggcaa ccgtctcctt tgccggaagt ggtaagatca ccaaaaaata cgcacacaat
    30061 aaataaaaaa cgaaagaata caaaataact gcccttgtta ctagaaatgt tccatacttt
    30121 cgatattcat aaataaaaaa aacagatgag atcgctaagg ctaaaaatgg aaaaacaatc
    30181 agcgcaaaac gaatcggttc gatataactt gccatatgac tcctccttga ttctttgtat
    30241 ctctcttatc ttagcagtcc tttgctgttt caagcaagta acgaggctat tatttctcat
    30301 ttctttcaaa gtaaagtaag ataaacacaa agggggtgtc gagatgctga atatgtactt
    30361 tgtttttggc gtacctattt ttttactgtt cctttatgct acgatcgctt atgtaagaaa
    30421 aagaactaca attcattatt taggatttat tctcctgatt atttcgggtt tcatgctagt
    30481 cttcaatctt cagacttggc agcaagcact tcttgaaatg gataaaatga ctccacatgc
    30541 tttgtctaaa gtgcttggct accctgtcta tctgatttgg cttcccattt tcatttctgg
    30601 ttgcttggtt ttattaaata tttatcgcgg cgtacgccga atagttcagt tacgcaaatc
    30661 aaagtaaaag acagaaatcg gttgagcccg atttctgtct tttactttgc tatttcatcg
    30721 tagacaaaac gacatttacg tgatcaaaat taacgagtac ttttgacatt tcttccacgt
    30781 actcctcatt taaataaaat attttgtttg gcagagaagt gcagttctaa taaaattcga
    30841 atgttttagc tatctacgtt ttaaatagag ataaatcggg ataccagcaa gtgtcaatac
    30901 tatccccatc gaagctaaaa aggtctgagt gataagcgtg cttgatacga taaaagtccc
    30961 tccaatgatt gctactagtg gaataaacgg atacattgga actttgtatg gtcgaaacaa
    31021 atcaggttct tttttacgaa gaagaatgac accaacaaag accatcgtat aaaaaatcca
    31081 aatgacaaag atcagcatat ccgttagtgt atcaaaacca ccgatcatca tcatgccaat
    31141 agcgatgact agctctaaga tacctgcggc tacaggaact ttagttttat catgaagttt
    31201 agcaaagagc ttgctaaaag gcaggttgtt ttcttttgcc ataacataag ggagacgcat
    31261 tccagtaagg gtatagccat tgatggttcc ataaacagaa atcaagatac caactgtgac
    31321 cagtcttcca ccgaagccgc caaaaatcat ttttgcaacg tcacttgccg cattgctgtt
    31381 tcctgcgact ccgtcgatag atgcggttct taagaacacc gcatttacta ataaataaac
    31441 gatcatgatt ccgatgattc ctaaagaaat tgcttttggc aaatctttcg ccggcttttt
    31501 caattctccc gaaatatttc ctacgtgtat ccaaccgtcg tatgcgaaca tcgttgctag
    31561 caagcccgct cccaaggctg agaaaaatga aagattttct cctgcttgga tcggaaacag
    31621 ttggaagtct actccttctt gtcggaacaa accgaaaatg acgatcacaa acaaaggaat
    31681 aagcttgcag acaagcgtaa tcgactgaaa agcccctcca gctttagaac ctaaaaaatt
    31741 gatcaacagg atcgatacag cagctgtaac agctacggga acaatcattg actgggaaag
    31801 accaaataga ttgacgaact gtgtaccgaa aatgatcgac aaggctgcta catttgctgg
    31861 aaaataaatc acgacttgcg cccagcccaa taaaaaagct gctgtatttc cgtaaatccg
    31921 ttcgatatat ttaatcatcc ctcctgtttc tggaatagca gctgccagtt cagctcctgt
    31981 tagtcctgca cagacagaaa tcataccacc gagaaaccaa gaaaacatat gcaaactggc
    32041 ggatcctgta acttctgcta cgcttgcggc tttaaaaaat acccctgcac cgatcactgt
    32101 gcccataaca gtcgataaag cagtaaaaaa tcccatcgta cgttttaatt cattttctat
    32161 ttttacttct tttactggcg tggcttgata ttcttccatc ccttgtcccc tttcatacca
    32221 tagccaatcc caaaagtata aaaaactttt tggatgtggt tcttgtttta taccgtctct
    32281 accaattttt ctttcagttt ttccaacata tcctttgtca tcacatctaa gtcgtatttc
    32341 ggcgaaaagc cccattcctc ttgcgcacaa gaaacatcta gtgaatttgg ccaagattct
    32401 gctattgact gacgtacagg atccacatca taatccattt caaaatctgg tatgattttt
    32461 tgaatagatg ctttgatctc ttccgggtca aaagacatcg ccgatatatt gaaggcattt
    32521 cgatgaacca atcgatcagg atctgcattc atgagtttta taatggcatc gatcgcatct
    32581 ggcatataca tcatatccat tgatgtacct tgatcaatga aactagtgta ctttccttct
    32641 ttgattgctg aataataaat atcgactgcg tagtctgtcg taccgcctcc tggcaaggtt
    32701 gcataagaaa tcaatccagg gaaacggaca ccacgagtat ctacgccata tttcacataa
    32761 taataatcac atagtagttc tccagctacc ttcgttaccc catacatggt tgtaggacgc
    32821 tgaagagtat cttgtggggt atgatctttt ggagtatttg gaccaaacgc gccgattgaa
    32881 cttggcgtaa aaaatttcag ctggaattct ctagcgactt ccaatgcatt gaccagccca
    32941 gtcacgttca aattccaggc taattgtggt tttgcttctg caacagctga caaaagagca
    33001 gccaaatgaa tcaatgtgtc cacttgatat tgttctgcta tgctgcgcat tttttcgtaa
    33061 tccattacat ctaggatctc aaagatatcg tttttctcaa tgacttcagg catgcgtata
    33121 tctgtcgcaa tgacattttc actgcctagt tcttgacgta gccgtgtgat caactctgaa
    33181 ccaatttgtc ctaaacatcc tgtcaccaat acttttttca tgatgatcct ccctgatctt
    33241 ttttactact atcttcagat gattaacaat atatgcgtga acatgttctc taattttaaa
    33301 tagacgaaaa aactaaattt agttaaataa tttccatttc ttttcctatt ttttgataaa
    33361 ctgctactgc ttcatcaagc atttccctcg tatgttccgc agtcggcata tttctgatcc
    33421 tgcctgtccc aagaggcaca gttggataaa cgattggttt agcataaatc ccatgttcga
    33481 tcagcttctt agagaaagtc tgagtcactt tttcgtctcc caaaatgact ggagtaatag
    33541 gtgtttcaga cataccgatg ttatagccta cttttttcaa ttcttcttta aaataattag
    33601 cattttccca aactttttcg acaagttccg gatgttcttg catcaaagta atcgaagcca
    33661 atgcagctgc agctgcacct ggagttagcg aagtagaaaa taggaatggc cgacttctag
    33721 ctttcaacca gtcgattagt gttttcgatc cagctacata acccccaaca acacctatag
    33781 ctttcgataa cgtgcccatt tgcatatcga ttttgtcgct taatccaaaa tgcttgacgg
    33841 ttcctgcacc ttttccagtt acgcctgagc cgtgcgcatc atcgacgtag gtgatcagtc
    33901 catatttttc aacaatcgga ataatttccg gcaatcgtgc aatgtctcca tccatggaga
    33961 aaacaccatc tgtgatatac atgatttttt tatatttctt actttctatc gcttcctttg
    34021 cttttttctc aaggtctttc atatcttgat gtttaattcg gatgattttt gctccggata
    34081 agcggcaacc gtcaataata gatgcatggt ttaattcatc cgataagata gcatcttctt
    34141 ttgtcattac tgcagagata gcgcccatat tgcagttgaa tccagattga aaggcgattg
    34201 ctgcttctgt ccctttgaat tctgcgattt tttcttctaa ttgctgatgg attttcagcg
    34261 aaccattgat cgttcggact gctcctgctc ctacaccata agtttcggtt gcttcaatac
    34321 atgctttttt caattcttcg cgattggcaa atccaagata attgttggat gctagattga
    34381 tcatcttttt tccgtctacg atgatacaag caccattttc actttctagt atgtcgatcg
    34441 tattgtataa ccccttttct ttcagttgat ccaattcttt ctctaaatac attgttagtt
    34501 ctttggaaga cattgtctcc acctccatat tcatctgtct tgcagaacat accaaacata
    34561 tatcgtgtca ttcatctaca aagcaagtat gctatatttt tgataacgct tacactgatt
    34621 atgagaatta tttaaccaca ttttttattt acagtatctt tttactttca aatgacttat
    34681 atagtatgaa caattacctt ttagataatg atctatttta ctctacctgg gcagataaat
    34741 acaacacaac cattgataga agccctttcg ttaaaatcaa ttgtattctg aatatttaat
    34801 ttatttattg catagaccaa taaaaataca taaaatttcc atcttcgttt atcagcaatt
    34861 tttaatttta ctctctgaat atttcttaaa agttttactt gttgaattcg aaaaaaggac
    34921 tgtgacaaaa gtcttgtcac agtcctattc tt
//
LOCUS       DAZUJR010000020        34604 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.020, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000020 DAZUJR010000000
VERSION     DAZUJR010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34604
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.020"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..798)
                     /locus_tag="ACG804_000912"
     CDS             complement(<1..798)
                     /locus_tag="ACG804_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFS4831860.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEK"
     gene            complement(1022..2962)
                     /gene="thrS"
                     /locus_tag="ACG804_000913"
     CDS             complement(1022..2962)
                     /gene="thrS"
                     /locus_tag="ACG804_000913"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HFS4831861.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(3299..3478)
                     /locus_tag="ACG804_000914"
     CDS             complement(3299..3478)
                     /locus_tag="ACG804_000914"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016862 - intramolecular oxidoreductase
                     activity, interconverting keto- and enol-groups [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxymuconate tautomerase"
                     /protein_id="HFS4831862.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(3525..5348)
                     /locus_tag="ACG804_000915"
     CDS             complement(3525..5348)
                     /locus_tag="ACG804_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFS4831863.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            5626..7905
                     /gene="helD"
                     /locus_tag="ACG804_000916"
     CDS             5626..7905
                     /gene="helD"
                     /locus_tag="ACG804_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase recycling motor HelD"
                     /protein_id="HFS4831864.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(7998..8645)
                     /locus_tag="ACG804_000917"
     CDS             complement(7998..8645)
                     /locus_tag="ACG804_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831865.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(8824..9543)
                     /locus_tag="ACG804_000918"
     CDS             complement(8824..9543)
                     /locus_tag="ACG804_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4831866.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(9674..10825)
                     /locus_tag="ACG804_000919"
     CDS             complement(9674..10825)
                     /locus_tag="ACG804_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HFS4831867.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(11042..11782)
                     /locus_tag="ACG804_000920"
     CDS             complement(11042..11782)
                     /locus_tag="ACG804_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFS4831868.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(11786..12109)
                     /gene="rsfS"
                     /locus_tag="ACG804_000921"
     CDS             complement(11786..12109)
                     /gene="rsfS"
                     /locus_tag="ACG804_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HFS4831869.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(12166..12759)
                     /gene="yqeK"
                     /locus_tag="ACG804_000922"
     CDS             complement(12166..12759)
                     /gene="yqeK"
                     /locus_tag="ACG804_000922"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HFS4831870.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(12743..13393)
                     /locus_tag="ACG804_000923"
     CDS             complement(12743..13393)
                     /locus_tag="ACG804_000923"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HFS4831871.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(13403..13714)
                     /gene="yhbY"
                     /locus_tag="ACG804_000924"
     CDS             complement(13403..13714)
                     /gene="yhbY"
                     /locus_tag="ACG804_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HFS4831872.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(13730..14839)
                     /gene="yqeH"
                     /locus_tag="ACG804_000925"
     CDS             complement(13730..14839)
                     /gene="yqeH"
                     /locus_tag="ACG804_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HFS4831873.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(14836..15363)
                     /locus_tag="ACG804_000926"
     CDS             complement(14836..15363)
                     /locus_tag="ACG804_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HFS4831874.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(15543..16328)
                     /locus_tag="ACG804_000927"
     CDS             complement(15543..16328)
                     /locus_tag="ACG804_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HFS4831875.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(16321..17190)
                     /gene="accD"
                     /locus_tag="ACG804_000928"
     CDS             complement(16321..17190)
                     /gene="accD"
                     /locus_tag="ACG804_000928"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HFS4831876.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(17191..18570)
                     /locus_tag="ACG804_000929"
     CDS             complement(17191..18570)
                     /locus_tag="ACG804_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HFS4831877.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(18578..18997)
                     /gene="fabZ"
                     /locus_tag="ACG804_000930"
     CDS             complement(18578..18997)
                     /gene="fabZ"
                     /locus_tag="ACG804_000930"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFS4831878.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(19022..19498)
                     /gene="accB"
                     /locus_tag="ACG804_000931"
     CDS             complement(19022..19498)
                     /gene="accB"
                     /locus_tag="ACG804_000931"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HFS4831879.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(19501..20736)
                     /gene="fabF"
                     /locus_tag="ACG804_000932"
     CDS             complement(19501..20736)
                     /gene="fabF"
                     /locus_tag="ACG804_000932"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HFS4831880.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(20755..21492)
                     /gene="fabG"
                     /locus_tag="ACG804_000933"
     CDS             complement(20755..21492)
                     /gene="fabG"
                     /locus_tag="ACG804_000933"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HFS4831881.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(21504..22421)
                     /gene="fabD"
                     /locus_tag="ACG804_000934"
     CDS             complement(21504..22421)
                     /gene="fabD"
                     /locus_tag="ACG804_000934"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HFS4831882.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(22528..22752)
                     /locus_tag="ACG804_000935"
     CDS             complement(22528..22752)
                     /locus_tag="ACG804_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFS4831883.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(22805..23767)
                     /locus_tag="ACG804_000936"
     CDS             complement(22805..23767)
                     /locus_tag="ACG804_000936"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HFS4831884.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(23777..24217)
                     /locus_tag="ACG804_000937"
     CDS             complement(23777..24217)
                     /locus_tag="ACG804_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFS4831885.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            24523..25488
                     /locus_tag="ACG804_000938"
     CDS             24523..25488
                     /locus_tag="ACG804_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFS4831886.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(25545..25775)
                     /locus_tag="ACG804_000939"
     CDS             complement(25545..25775)
                     /locus_tag="ACG804_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HFS4831887.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(25861..26748)
                     /locus_tag="ACG804_000940"
     CDS             complement(25861..26748)
                     /locus_tag="ACG804_000940"
                     /EC_number="1.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFS4831888.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(26837..28060)
                     /locus_tag="ACG804_000941"
     CDS             complement(26837..28060)
                     /locus_tag="ACG804_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFS4831889.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(28077..29123)
                     /locus_tag="ACG804_000942"
     CDS             complement(28077..29123)
                     /locus_tag="ACG804_000942"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFS4831890.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIRSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(29287..31014)
                     /gene="ptsP"
                     /locus_tag="ACG804_000943"
     CDS             complement(29287..31014)
                     /gene="ptsP"
                     /locus_tag="ACG804_000943"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HFS4831891.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(31014..31280)
                     /locus_tag="ACG804_000944"
     CDS             complement(31014..31280)
                     /locus_tag="ACG804_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HFS4831892.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            31759..33993
                     /locus_tag="ACG804_000945"
     CDS             31759..33993
                     /locus_tag="ACG804_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFS4831893.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            34141..34461
                     /locus_tag="ACG804_000946"
     CDS             34141..34461
                     /locus_tag="ACG804_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HFS4831894.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
BASE COUNT         9779 a         7494 c         6045 g        11286 t
ORIGIN      
        1 tttttcgcta agcttttcgt ttttagccat atagaaataa aaaatgatat cgatcgtagc
       61 aaattgggcc aaaagtgaat tagttgccgc acttcgattc gtgatttctt ttggtctaga
      121 tgtttgtacg agtacatcgg ctatcttgct aagcgggtta tttccaaatt gcgtcaacgc
      181 aatgatttcg atattcatgc ttttcgccag ctcggctaat gcgactacat ctgcacttct
      241 acctgagttt gaaacaagcc aaagcacttt ctttttctca ttgctgacaa gttgcgggag
      301 caagacgtgg atatcttttt caaaaatgat tggcttaccg acacgagacc atttttgcag
      361 aatatcttct actactaaag aagaggcgcc aaccccatat aaaaaaacag tctctgccga
      421 ttccaaacac tctacgactt tttggatcgt ttcttcttct agaatatcta ctgtttcttt
      481 tatcgctact tgtgcattgt taccaagttt gtttttgata gagtaaaagg actcatttgc
      541 ttctatatca ctaaaacctt catcgattcc agtctgtagt tctgttgaaa tcgtgatttt
      601 gaagtccgtc agactttgaa aaccgatttt tttggaaaaa cgtacaactg tcggcgcact
      661 caacccggaa gcttctgcta attcattagc tgtcattgta gggaccttct caatattacc
      721 gataatgtag ttggccaact ttttttctgc tgaagaataa tcttccatca tactttcaat
      781 acgactaatt acgctcataa gttcctccac ccttttaatg atagtctatg taagtatacc
      841 atatcagacc cttattcacg gtcgtatact ggataaaaaa caaaaaaaca atccgcccaa
      901 cagaatatct tatcccatca atcccacaga ttctattgag catctgtgtc tttgaggaat
      961 acctgttatc tattgttcgg attgctttct atctactact tttttacagg aaatttacct
     1021 attagttttc tctgctgtaa tttttgactt ctgcttccat agcatcaata aagatattca
     1081 aatcttctac agctgtttct ttacttccat aacgacgtac gttcactgtt gcatcttcca
     1141 attccttgtc tccaacaact aattggtaag ggatcttttg tgtttgagag gcacgtatct
     1201 tatagcccat tttttcatta cgatcatcaa cttctacacg caaccccttc atttgcaaac
     1261 gttctttgat ttcataagca taatcgccat gtgcatcaac agaaacaggg atgattgttg
     1321 cttgtatagg tgccaaccat gttggaaaag cgcctttgta tacttctgtt aaataagcga
     1381 caaaacgttc cattgtagaa acaattccgc ggtggataac tactggacga tgcgtatttt
     1441 ccccgtcttc tccaacatat gtcaaatcaa agcgctctgg caataagaag tctaattgta
     1501 tagttgataa tgtttcttct gtaccaagag ctgttttgac ttgaacatct agttttggtc
     1561 cgtaaaaggc tgcctcgcct tctgcttcaa agtaatctag ttctaattca tccatagcgg
     1621 ctttcagcat tgcttgggct ttttcccaca ttgcgtcatc atcaaaatat ttatctgtat
     1681 tgtttggatc gcgatagctc aagcggaaac gataatctgt aatattgaag tcagcatata
     1741 ctgccaccat caattcaagc gtacgtttaa attcatcttt gatttgatca ggacgaacaa
     1801 atgtatgacc atcattcaac gtcatttctc gtacacgttg taaacctgac aaagcacctg
     1861 atttttcata gcgatgcatc attcctaatt cagcgatacg aattggtaat tcacgataag
     1921 aatggatcgt gtttttgtag accatcatgt gatgagggca gttcattggg cgaagaacaa
     1981 gcatttcgcc atctcccata tccattggcg ggaacatgtc ttcttgataa tgatcccagt
     2041 gtccagatgt tttgtacaac tcaacatctc ccattattgg tgtatataca tgttggtaac
     2101 ctagactaac ttctttgtct acgatataac gttcgatcgt gcgtcggatt gttgcccctt
     2161 ttggaagcca gaatggcaaa ccagaaccta cttctgggga aaccatgaac aagtcaagtt
     2221 cttttcctag tttacgatgg tctctttctt ttgcttcttc acggagacgg atatattctt
     2281 tcaaagcttt cttgtcaaaa aaggctgtcc cgtatacacg ttgcatcatt tgattgtttg
     2341 agtttccacg ccaataagca cctgccactg ataataattt aaatacttgt atacggccag
     2401 tggatggaac atgtggtcca cgacacaaat cgatgaattc gccttgttga taagcagtaa
     2461 tcacttcttc ttctggcaat tcactaatca gttctacttt gtacggatca cttgcaaaaa
     2521 tttctaatgc ttcctgtttt gaaagaacac ggcgttcgat cggcagattt tctttgacga
     2581 ttttcatcat ttctgcttcg attgccggca aatcttctgc agttacttgg ttttgtccat
     2641 tatctgtatc gtagtaaaac cctgaatcga tagctggtcc aacgccaaag tggatatttg
     2701 gatagaggcg acgcatggct tgggccatca aatgagctgc tgaatgacgg actaagccaa
     2761 gtgcatcttc atggtctggt gtgatgatct caatacttgc atcttcctcg attggacgag
     2821 tcaaatcaac gagttttccg ttcactttac cagctaaagc tttttttgct aagctttttg
     2881 aaatgctttc agcaattgcc aatgttgttg ttccagactc aaattctttg actgcaccat
     2941 ctggaaaagt aatttttatc ataatagttt cctccttgaa atgttttgat tgatcagatc
     3001 atcaagctga aaaacaaaaa aatcctagca tctcttgaaa agagatacta ggacgaaaag
     3061 ttcgtggttc cacctaatgt tcaaacgcaa atgcgttcct caagcgttgt aacggtccga
     3121 ccgcccttgc ttcaacaagg gtttcgaaag tggtcatcct ttggttttct cctggaaaag
     3181 tttcagccta gcttttcctc tcttatcgaa gactctcaaa ttcagttggc tttctcatca
     3241 atcaattatg tgtttattta accactaata aatagaaaaa tcaagtggga aactaaactt
     3301 attttttcca ttccccattt acaccgtatg ttcctttttt catctcattg atgatgacat
     3361 ggatgtgttc ttttggtgcc tgcgtgtttt tatgaacagc ttccgtgata tctttcatca
     3421 tattttctaa ttgttccgga ctgcgacctt ctactaattc gacatgtacg aatggcataa
     3481 tgctctctcc tctttctgat cgttcttttt tcaactcgat tctatcatac tatgtttgtc
     3541 ttgggtactg aatcaggaaa aatggctgga tctttttttg ctctcaaggc actcaaaata
     3601 gagaccgtat ccacgacttc ttgcaaaaca gctccgaata atgcggggat tagtcccgta
     3661 cttgcaatta acatcaaaaa aatacaaata aagatgccaa tcagtacaga ctgtttcgct
     3721 attctcatcg tatctcttga aatcactact gcttttgcta cacgcaagag atcatctttc
     3781 aagatgaccg catctgcact ttcactagca gctgtagaac catgagcccc cattgcaata
     3841 ccgatatctg cagcagcaag tgctggtgcg tcattcacgc cgtctcctac catcgcaaca
     3901 ggtctttgat ctttagggat actttctaaa atggtcagtt tatcttgagg caagctacgg
     3961 gcatgtacag aatctaattg gactttttct gcaatcgttt gagcaatggc agatccatcc
     4021 ccggtgatca tcatcaaatt tttcacatca agttttctta gctccttgat tgtctttgct
     4081 gcttctgggc gaatctgatc cgaaaatagg atcgttcctg caaaagatcg atcaattgtt
     4141 acatagattg ctgtattgga cgtttctatt tcttcagctg aaacaaaaga ggcacgtcca
     4201 atctttactt catgattatt gactactgct tggattcctt gaccggtcac ttctttcagt
     4261 tgactaacag gatacagttg gctgtttttc acgttgttca ctaacgaacg agctaagata
     4321 tggctagatt cctgttctgc actagctgca tacagaagta gctcttcttt ttttattcca
     4381 ttgactggct gaatcgcctc tacttccaat atccctttgg taagcgttcc tgttttatca
     4441 aaagcaatcg tttttgtacg tgcgagcttt tcaatcgttg ttccagtttt tacaacgatc
     4501 ccgtttttac ttgaacggct cattcctgca actaaagcaa tgggcgcagc tagaatcagt
     4561 ggacaaggtg atgccactac cagtacctca gcaaatcgta aagggtcttt tgagaaccac
     4621 caagaaatac caccgatcaa ataagcaatc aacgtgaaag ggactgcata acgatcagct
     4681 aaacggacaa atcgggcagg cttttctttt gattcttcga ctagtttaat aatcatttga
     4741 tactggctgt ctgcggcacg tttttcagcg atcatttgga tcgatccgtc tccatttaaa
     4801 gaccctgaca taatctgatc tccaggtttc ttggtttccg ggcgggactc acctgtcaaa
     4861 gaagattcat cgaccgaaga ttctcctttg gtcactcgac catctgcggg tacaagttcg
     4921 ccaggcttga ctagtaactg gtcatcaata tttatttcat cgattactat atcctgcaat
     4981 tttccttctt tgaatcgatg ggcaattctt ggggtgttat ctaacaaaga ctgcagttct
     5041 ttacccgctc gtttattcgc gtaatcctct agactatctc cgcccgtaag catgatcaat
     5101 atcatcaaac tagcccagta ttctttgacg gctaatgttg caaggattgc ggtaatcgct
     5161 aatacatcta cgccatatct tcctgaacgt aacgtcttga tcatttccaa aaacatcaag
     5221 aaggcgagaa tccctccagt aaatgcgaca atcgcaaatg caagggccgg ctggtgaaaa
     5281 acaaattcac ttaataaagc tatcccacca ataagcaaag taagtaaaaa ttttttgaaa
     5341 tgtgtcattg ttttttctcc tcttttatgt gacttagaga ggttagtaat aaatttccag
     5401 ctgcctcttt catcttaagc atagtccttg actagcactt tttaaaacaa taggccttaa
     5461 ttgaaaacaa ctatcactat cagcgtttcc aaaattcatc agttctacaa acaaaaatat
     5521 tcagcaagga ttactttttc gattcatcag ttaaaaagta ccttttttcg aaaaactatg
     5581 ctatactttt aattcgttat ttacggcgga aggagcaaac atgcgatgaa tgagaaacaa
     5641 ctagaacaaa cgcacgtgga tgaaacgatc gaactaatcc agatcgaaca aaatatgctg
     5701 gatacaaaac aacaagaatt gactcaggaa atgaatcatt cgacaaaaga cacagctaat
     5761 cacaagattc gagctggttc caatgaagct ttttatgaat ctgctgttga atatcgccaa
     5821 catgagcagg aattgctttt gaaataccat actcttgaag cacagcaaaa acgcctgcaa
     5881 acgttgtctg tcatgaaaga tagtccttat tttgcccgta tcgactttaa agaagaccgt
     5941 gaaacagaaa cattatatct aggtatcgct tctttaagag atctggcaga agaaacaatc
     6001 gttattgact ggcgcgcacc aattgccaat ctttattatg aaggtgagat tggtcccgca
     6061 ttttatgaaa ctgaaacaga tagaatagat gtcgatctgc agttgaaacg acaatttaaa
     6121 atccaagaag gacgtatttt atctatggta gatacgtcgg aagtaatcaa tgatgacttt
     6181 ttgctagaga tattggatga atcatcaagc aaccatatga aaaacatcgt ctctacgata
     6241 caaaaagcac aaaatgcaat cattcgggac acaacaagta aagtaatgct gattgaagga
     6301 atcgccggaa gtggaaagac atccgctttg cttcaacgta ttgcttttct gttgtatcat
     6361 aatcgcaagt ggctcgaggc tgaaaacgtt cttctatttt cacccaacca tttgttttct
     6421 gattacatct cgactgtatt gccttcatta ggtgaaagcg gcgtgcctac acagacattc
     6481 aaaaattatt tggtgcagct gctgccagag ttttctttac tagatgaaca gcaacaagaa
     6541 agtggttttt tgctagggga aaaagatccg atacaagtga tgaaaagcgg attgacctta
     6601 gtcgatcaga ttgatcgcta tatccaaggc atcacaaact acggtccctt gttccgtgat
     6661 atgaaaataa atggccgtac gatcctatca aaggaatcga ttcgccaatg gtataaagaa
     6721 acaaatgaac aattaccttt acatcataga ctttctctat tacaaacgaa gctcctgaaa
     6781 aaattaggcg gtctgcaaaa agacgaaaca cgtcagcaat gggtcaaaga tctggcggaa
     6841 gaacagctcc aagaactata cgcaacagat ccaaatcttg aatatacaga acaaaaggag
     6901 cgttcattac gtaaaaaact ggccaaccaa atcgtacgta aaagattccg tcgaatccat
     6961 cgagggatca tgaattatca atttgtcaat ataacgaaac aatatctcca ctttctacaa
     7021 actgtgccac tttctcttct aacacgacat aaaatcagcg agaccaggtg gcaggaacat
     7081 ttgacaactg ttcgtacaca cttgcgtcaa agagaattgc gtcaagagga tgctgtacta
     7141 ttctttttac tgatgcgccg aacatatcca gtgacggtta cacacaaagc tcgctatatc
     7201 tttattgatg aaatgcagga tttcgcacca tcacaagtgg cattgctgca agccttgttc
     7261 ccaaaagcaa atttgacttt ctgtggagat ctaaatcaaa atgtctttgg aaatgaaacg
     7321 atcgttggat cattggaaga ccttttcgtg gaccgtgaag tcactcgttt ccaattaacg
     7381 acaagctatc gctccacaaa agaaatcact gattttgcta atcattttat tgtgaaagaa
     7441 catcaagtag aaacaacagc aagaaaagga gaccttcctt tgctcatcca aggaacaaca
     7501 gatgatatca aattgaattg gttagcagat accattcgaa cgactcaggg aaaagcccgg
     7561 tattggcgta cagcaatcat agctaaaaca caagaagaat gcgaagctct ttatgctcaa
     7621 ctgccagacg agttgaaaca acaagtccag ctgattttaa atgagagtga ctttatgaag
     7681 cgttccatta ttttacttcc agccttttta gcaaaaggtc tggagtttga ccgagttttc
     7741 ttgtgggatg tagatgcaga acatttttct tctcagcaag acaaattgat cctttacacc
     7801 atgtgtacac gtgcgatgca tgaattgacc ctttttacct ccaataatga aagtcctttg
     7861 ttaaacaata tggatatttc atcttatgag aaaaaagtac tgtaagtaaa aagacaactg
     7921 ctatcattaa tgttagcagt tgtcttttta tttacaataa taattgcaga aaaagtaatt
     7981 caatcattta aggtcattta ttctatatat aaatccaaat ctgtttcagg atattttaat
     8041 ttgacaagcg aaataatcat tttcagttct tccatgtttt ctggatattc tgggtcaaat
     8101 accttgctat gacggccaat cccgccattg tcgatcaatc ggtaaattcg attccattca
     8161 atgaattggt caattgattg gaaattgctg attggatagc cgccacaatc caaaatctct
     8221 gatacacgaa atgctaggta tgcactatcg atcactttat tttttttcgt gtctatcttc
     8281 tcatttcttt cgataagaat tttttcagga cgatgtttca agctccactc taatagtaga
     8341 aagaaagcct ccatccgata ctcttcttca aataaccgaa aggctgaatc agaacgacga
     8401 aaaagcagcg gaatcagata attttgtcta taaatcagca ttggtgcgcg gtccaccata
     8461 cactctaaat aacggttcag ataccctgta ccgacatagt ttcctaatcg atagccttca
     8521 acgccgaatc ttgcgtattt ttgcgctaat tttgaacaat cagttacgtt cacagctaac
     8581 tcttctactt tgcggtaacc gcttaagata cgttcaaaag gttctaaagt gatttttgct
     8641 tccatattct tccccgtcca tcttccacat acttcatatc atttcacatg atacttatgc
     8701 tctcatcata ccacaggttg aattagaaaa gaaaataaat cacacaaaaa agcaagacaa
     8761 tctgttagtg agattgtctt gcttttcgaa aaagactgaa tacttttcgt taaaactggt
     8821 tgcttagtct tctaatgcca cattatggaa cacatgctgt acatcttcta gatcttccag
     8881 tgcatcaatc attttttcaa atgtttcttg atcttctgga gatagtgtta cctcgttttg
     8941 agggatcatt tggatctcag cgattgaaaa atcagtgatt cctttttctt ttaatgcttc
     9001 ttgtatacta tggaaatccg ctacttcacc gtaaacgatg atttgtcctt cttcttccat
     9061 tacatcgcga acatcgatgt ctttttccat taggtattca aggatctcgt cagcgtcttc
     9121 tcctgcaaaa gcaaagattg ctgtattgtc aaacatgtaa gaaaccgctc cggaaacacc
     9181 catgttcccg ccatttttcc caaatgctgc ccgtacgtct gctgctgttc gattcacatt
     9241 gttcgtcaat gtatcaacaa tcaccattga gccgcttggt ccaaatcctt catagcgcaa
     9301 ttcagagtat gtttcatctc ctgcaccttt tgctttttcg attgctcggt caataatatg
     9361 ttttggtaca ttataagttt tagcgcgatc aatgacgaaa cgtagttttt ggtttgcatg
     9421 cggatcagga tcacctgatt ttgctgccgc gtagatttca atcccaaatt ttgcataaat
     9481 ccggctatta ttagcatctt tagcagtttt ctttgctacg atatttgccc atttacgtcc
     9541 catattttca cttcgctttc tgatttgata gtttcataac gcaaaaacgt cctgttccat
     9601 tatacttgtg aatcacgatt ctgtgaagct ttttttcttt cttccttcat tcttctcatt
     9661 tttagtcaat tatctatact cggattggga tttgcccgaa attctgttcc ggaatattgc
     9721 ctcccaattg atagatttga tcacttctaa ctaacagttc cgcttcttgt gcctcttttt
     9781 ttccgattcg ggaataaata gaaatctctt ttttttcttt taagaatctt cttccagcat
     9841 cggtaaatcc aagtagtcga agataatttt tattttgttg gacaggaatc tcttgctttt
     9901 tgatattcag caagacataa caagataatc gttggatccg tgtccatgta tatctttttg
     9961 tttttacctt tgacacaaaa tcctcaaaac tatcagcagt tgcagctgct gttttcatgc
    10021 gcgattctat tccttcggtc atctgataga tatctgtcag ttccagcaaa gtagaagata
    10081 acaaccgata acgcaaatac ggccaataag attcccaagt ctgcagcgaa caagttgaaa
    10141 gatcttcttc tgtctgaggc ggcacaagtc cagctattct ttttccttct tctaacgcat
    10201 ggcgaatggc tgttgcactg gctatcctct gatctgtgat gattttttca tgatagcctg
    10261 cacttttacg tcggatcgga tgtaattcca tagggtggac atacttggca ttttcctttg
    10321 cataacttaa tcccaagata tgatttggcg aagaaaaatc aagcgtaata tcgggataca
    10381 gactgcgaaa aacctcagtc attttttgcg gataactata cgtttgatca gacagttctt
    10441 gaaatgcctc ttctatccta tcttgattct cttggacaaa gcgtccgaaa ctgctgtaat
    10501 caaacgaagt ctcttcttct gttccaaaac acaaactgtc acagtccagt gtttgcaaga
    10561 tttttactgc acctttagca aaatagtcag ctgactgaac cgcccattcg acgggaagct
    10621 ccactactaa atccacacca ttttgtaaag cttcattcgc gcgatgccat ttatcgatga
    10681 tagccggttc gcctctttgc aaaaaattcc cgctcattac agcaatgacg acctctgctc
    10741 ctgttatttt tcgtgccatt tccacatgat agcgatgtcc attgtgaaaa ggattgtact
    10801 ctacgataat cccgcagctt ttcatgcgca tcctccttca tagttatcga taaaaaagaa
    10861 atagagacaa gtaaaaaaag gcaaaaatcg gaaaaaatac ccgaactata taaactattc
    10921 tcgcaaacac aatacttctg cgacgaaaag ctgcactgca agagcaatgc ctatatcgtt
    10981 cggatatata atttatgttg aagatttatt cttttcttgt taactcgagc aggcaaaacc
    11041 gctagtcttt gtatgctaca aagaaccagc gctttgattt ctctgatgct gcttcgtctg
    11101 taaaatcaga aaatgcttcg actttcgaaa agccgctgtt ttccagcatt cttaaataac
    11161 tttccaatgg ataggtacgc tcttgatgta gttcatcttc acgaataaat cgaccagacc
    11221 cttcttgttc ttcaacgaaa aaggtaagaa aatgttcgat gctgtgtttc tcgcttcctg
    11281 gataactatc ccacaaaaaa gcaaaattat ccccttgata atgatagcta tattctggaa
    11341 aaacctcatc tacttgatag gtggagtgta cgtcaaataa aaatcggcca ttttcttcta
    11401 acgcttgata gacttcatca aacacttgct gtacctcttg tctatttttc atatagcaca
    11461 gcgaatcaga aaaacaggta attgcctgat attgtccgat ttctgataaa tcgagcatat
    11521 tgccttccac aaattggatc gatgcgtctt cttcatatgc tcgctggctg gcaatcatca
    11581 acatctcttc tgaaaggtct aaccctgtca ctttatatcc atcttttgca aaggcaaccg
    11641 ctaatgctcc agtaccgcat gccagttcca aaatattttt tgtgtcttct tgtaaatgac
    11701 gtttcgaaaa agctaaccat tgctgataaa gtgtttcgtc catcacttca tcgtaaatga
    11761 aagcaaatgt ttcataagcc atatgttaat ccaaccattc actaagatcg actagcggag
    11821 catctgacca tagtttttcc agattataga aatttcgttc tggcgcatgg aaaacatgta
    11881 cgatcacatc tccaagatcg atcaataccc attttccgcc ttcttttcct tcaatacgtt
    11941 ttacttcata tttgttttct tcttctttat caatgatttc ttctgtaatt gcgttgattt
    12001 gacgttcgct atttgctgaa cagatcatga aataatctgc caacaaggaa acatttcgaa
    12061 cgtctaaagc gataatgtct tctgcccgtt ttgaatctgc tgcttcaatc gcaattttta
    12121 attgttcttt actatctatg atgatttcct cctaatatga gcagcttatt tttttgctac
    12181 ccagtaatta tatgtttcga ttgtttttgg ataaatctgt tgttcttgcg caagcaaatg
    12241 ggccaatgta tgttttgttt caaatgctac agcttcgtct agatcagccc atgcaatggc
    12301 tcgtgcatct tgtaccccag gaaaatctcg acctggttca atatagtctg ctacataaat
    12361 gattttgtca aggagactca tcttagcagc cccagtcgta tgcacccgga ttgcatgaag
    12421 aatctctgca tcggtgattc ctaattcccg ctctacaaac gaagcgccaa caagaccatg
    12481 ccagattgca ttattataat tcaataactc cggatcaaaa ccgtctctta cgattaccat
    12541 tttgaactcc tcatctggtc gttcttttgc ataatcatgt gtcaatgcag caatactagc
    12601 tttttcagga gaagcaccgt attttttggc aagagccacg gctgtttctt ctactccaag
    12661 cacatgcttg aagcgttgtt cgctcattct catctgtatt ttttgcatca ggttttctct
    12721 agaataagca gtatattcat tactatagtc catattcata caacccttca ttttgaatat
    12781 aatcaattac tttatctgga acaaggtagc ggatagaaca gccttctttg atcttttgac
    12841 gtattttcgt ggaactgatg tcgatctcag gtacatctac ccaaattaca ggatatggag
    12901 tatccgttgt gtatcctggt cgacgtatac ccacaaagtt gaccatagaa gtcagctcat
    12961 cgattttata ccattttggc aaatattcta ccatatcccc accgataata aagtaataat
    13021 ctgtatccgg attgttttgc gtcaattcct tcatagtatc ataggtgtaa cttttcccac
    13081 cacgagctaa ttcaatcgtt tcaatctgca aaaaaggatt gtcttccacc gctaattcca
    13141 acatgttgag tcgatgtttt gcatcaatcg tctgtttctc atcaacatga ggtggctgat
    13201 aagaaggcat caaaaatacg cggtcaagac ctaaattccg gccagcttgt tcagccatca
    13261 ctaaatgtgc aaggtgaacg ggattgaatg ttccgcccaa gatccctact tgctttttct
    13321 tctctaagaa ttgaggcatt tcttcaggaa ataattgtga acgaacaaat gtcttagctt
    13381 gcgtattcat catggtcact ccttatattg cttttacttc ttttgatagc ctttgatact
    13441 tttcttttgt ggaaggtttg tataatacaa taacacgtcc aatgatttgg acgatttcgc
    13501 aatctatttc tttttctaat acttgagctg cttcttctgc aatctcatct gtattttgaa
    13561 gtaacgatac tttgatcagt tctctttttt ctaaagcttc ttcaatttga acgatcattg
    13621 ctgaattgat cccacctttt ccgatttgaa aaatcggctg aagatgatgc gctttgctac
    13681 gtaaaaaacg cttttgtttt cctcttaaac tcataatttt ccttcttcct taaatcaatg
    13741 ctttgcgttt caatacatct acaccctttg gcgcccagcc cgcaattact actggcgctg
    13801 ttacagtgat ccagcctaga ccggcaaaaa cgatgtctgt tttttctttc acagaaaact
    13861 caaaacgaac aagctccgga aatgcctcga cttcatcagg acgaggaggc tgtaataatc
    13921 cacctacatg tttttgataa aattcgtctg ctttttccag tttcgttcga tgaatattta
    13981 catcatttga cacataagca ataaatgaag cacgattgcc gctgataaaa tcaaatcttg
    14041 caagtccgcc caagaaaagt gtttgccctt cattcagctg ataaacttta ggtttgattt
    14101 cttttaacgg tgcaatgatc cgcaaatctt ttttacctaa gtagtgcgcc atttgatggc
    14161 gatggataat tcccggtgta tcaatcaaaa aatgcccgtc atctaaagga atctcgattt
    14221 tatccaaggt cgttcctgga aactgcgaag ttgtgattac atcttgtact cccgctgtat
    14281 ttttgatgat ttgattgata agcgtcgatt ttccgacatt tgttactccg acgatataga
    14341 catcccgtcc atcgcggtat tcttcgattt tttctaatag ttccgtcatc tcatgagatt
    14401 tcttagcact agttaataat acatctactg gacgaattcc tgcttcgtaa gcacgttcct
    14461 tcatccattg tgttaattta gtttttttca atgatttagg taatatatcc actttgttcc
    14521 caactaaaag tactggattg tcaccgacaa aacggtgtag tcctgggatt agtgaaccat
    14581 tgaagtcaaa aatatccacc acattgacga tcaatgcatc tttttgccct aattcattca
    14641 gtaagcgcaa aaagtcgtca tccgtcaatg agacatcttg ggtctcatta taatggcgta
    14701 atctgaaaca acgctgacaa tagacttccc cggaagctaa acctttttcc aaagccgttt
    14761 gcggcgtgta tcctaattca ccgggtttgt ttgtttgtat aacggcacca cagccgatac
    14821 attgtaattc ttctgtcatt cgattccacc tcgccagccc atatcagggt gttttgctaa
    14881 tagataggcc ataattcttt tttcccaaaa acgattaaat tgtgtcttcc aactatctgt
    14941 tgcgataatg ggttttacaa ggatgctacg tatccctgca cgattggctc cacgtatatc
    15001 agtcataatc tgatcgccta ccattactat ctcatcatct gctaaatcca attgtttctt
    15061 tgctatgttg atccctcttg ctaaaggttt cattgctcgt gcaacataca aaagatcaaa
    15121 tttttcaatc gctcgcgcga cacgttttga attattgttt gaaacaacaa caacagggat
    15181 tcctgcattt ttcatttcta aaatccaagt aagcaactct tctgttccat ctggattatt
    15241 ccatgcaatc aacgtattgt ctaaatcggt caatactgct ttgatgccta gattctttaa
    15301 ttgggcaggt gtaatctgat agatggcttc taccatccat gttggtttgt aatttgaaaa
    15361 catgctgtct cctcatctgc aaaaaatgaa ggagcacata aagtactcct caaccccgta
    15421 ttatactgca tatcagcaaa aaaaactacc tctatactcg ttcgtctttc agaaaaagca
    15481 tttctttaca aaatgaccaa aaataaagat tgatcacaga aaaatttaga aacaaaaaac
    15541 aactaatatt ggcggaacct cttgtatcgt ttttccagta atttatgctg atctaatcga
    15601 acaagttccg tcaatctttc aatcaacgct tttttcataa tgtgtgcgac tttatatcgt
    15661 ggcaactgct cgccgttgaa cgtttcagga ataactcgat caacgattcc taactcgcgt
    15721 agttctggcg cagtaatttt catcaactca gctgcttctg cggcgcgact accgtctttc
    15781 cacaaaatcg acgcaaatcc ttctggagaa agcacagcat aaatcgtttc ttccagcatc
    15841 cagacttcat ccgctaaacc tagagcaagg gcaccgccac ttccaccttc accaatgatg
    15901 atggcgatga tcggtacctt taaatcagac atttcgagca gatttctggc aatagcctct
    15961 ccttcgccgc gctcttctgc tcctacaccg caatatgcac ctgctgtatt gatcaaggta
    16021 atcaccggtc tattgaactt ttccgcttgt ttcatcagtc gtaaagcttt tcgatagcct
    16081 tcaggatggg gagaaccaaa atttctgcgg atattttcct gcagatcccg tcctttttga
    16141 ataccgatca ctgttaccgg tttgccatct aatcgagcga ttccaccaac aatcgcttcg
    16201 tcatctgcaa ataaacgatc accatggcat tcctcgaaag aatcgaagat ctcttcaaaa
    16261 aaatccaagc ttgtccatcg ttctttagct cttgctaact gaacgacatc atgtgctgtc
    16321 ttatccacga tctatccatc ctttctgtgt atgcaattca agaagcgtat ggattttctg
    16381 tttcaattcc atgcggggaa caatctgatc gacaaaacca tgagataata agaattcagc
    16441 cttttggaaa tcttctggaa gttcctgctt gatcgtctgt tcgatgacgc gtcttccagc
    16501 aaaaccgatc aagctttggg gttctgctag aataatatcg ccttccattg caaaactggc
    16561 agttactcct ccggtcgtcg ggtccgttaa aacagttaga taaaaaagac cttcattgct
    16621 atgccgtttg acagcagcag agatttttgc catctgcatt agagaaaaga ttccttcttg
    16681 catccgtgcg ccacctgaag ctgtgaacaa gacgactgga agactttcct ttgttgctcg
    16741 ttcgaataat ctggtgatct tttctccgac aatcgttccc atacttccca tgataaaatt
    16801 aggatccatc actccaataa tgaagggaat cccctgaatg gttgctttac cagtgaggac
    16861 tgcttcatga agtcctgttt tatcttgcat ttttttaatt ttttccgtat attcgggaaa
    16921 tgctagcgga tctttggtta caagatccgt atcccattct tcaaaacttt tttcatcaat
    16981 aatcaaagct agacgctgcc atgcaccgat tcgaaaagcg tatccgcaat gagggcatac
    17041 tttttcttca ccgatgtctt tcgtataaag gatatgtttg caatttggac actttgccca
    17101 catgttatca ggaacagatg gcgagttagc aggtttgctc tctctattag gattgatccg
    17161 aatatatttc tttttcttaa acagagccat ctatgcgcct cctatctccg tttctggtgt
    17221 ccaattcggt aaaaattctt cttgtaaaaa tgctgtgctg taatcacctg ctatgactgc
    17281 aggatgacta atcaaatcca tctgaaattc tgcgttcgtg atgattcctt ctgtgataaa
    17341 ttcacttaag gctcgctgca tcttcattaa tgcttcaaaa cgcgtatttc catggacgat
    17401 tatttttgca atcattgaat cataatatgg cgggatcgta tatcccgggt aaactgcact
    17461 gtctactcgc agtcccatcc cacctgctgg aagcagtaag ttttggatct tccctggaga
    17521 aggagcaaaa tggaaagcag gattttctgc attaatccgg cattcgattg cgtgtccttg
    17581 gaatactact tcttcttgac acacattcaa aggctcaccg gctgctatct ccacctgttt
    17641 ttttactaaa tcgattcctg tgaccatttc tgttactgga tgttccactt ggattcgagt
    17701 attcatttcc atgaaataaa aatcgccttc ttcatccatc agaaactcga tcgttccggc
    17761 attttcataa ttgactgctt tagctgctcg aacagcagcg tctcctagtg cttctctttt
    17821 tgtttgtgag atcactacag aaggagattc ttccagtact ttttgattgt tgcgttgtaa
    17881 agaacaatct cgctcgccta aatgaatgac atgaccaaat cgatcaccta agatctgaac
    17941 ttctatatgg cgagcaggat aaatgatttt ttccaaatac atatcatcat ttccaaatgc
    18001 cgctgctgct tcttgctgag ctgaagaaaa atgctgtggg agctcttctt ttgattgaac
    18061 tttccgaatg cctttcccgc caccacctgc agctgctttc agcatcactg gataaccaat
    18121 tctgtctgct atttccaatg cttcttctac tgtagataat acaccagtac ttcctggaat
    18181 gactgggaca tttgcttctt gcatcaattg acgcgcattg atcttatttc ccattgcatc
    18241 gatcgttgca cttttaggac caataaatgt gatattgcac tcttcacaca tggaggcaaa
    18301 tcggctattt tcagataaaa aaccaaatcc tggatgaatt gcttcggctt ttgtcacgat
    18361 tgcagcgctc agtacttcct gaacattcag atatgaatca acggcttttg ccgggccaat
    18421 gcagattgct tcatctgcta actgtgtatg aagtgcttcg gcatctgctt ctgaatatat
    18481 cgctacggtt tggatcccta gttcgcggca tgcacgaatg atacgtacag cgatttcacc
    18541 gcggttagct atcaatactt tagaaaacat atttcaccta tccaatcata aaggttaatt
    18601 ccgcttcggc tactttttta ccgtctactt tagcgattcc tttgcctatt ccggctgaag
    18661 ctttcacttt caatatctca acttcaaggt ataaggtatc tcccggtgta actttcttac
    18721 ggaattttgc tttgtccaat ccgccgaaat aagccgtctt tcccttgaat tgttcaagag
    18781 aaagtaatgc aactgctcct gcttgagcca ttgcttcaac aatcaatacc cctggcataa
    18841 caggttcttc tggaaaatgt ccttgaaaaa agggctcatt gatcgttaca tttttcttag
    18901 caacgatccg ttctccttca accatttctt ccactcgatc aatcaaaagc attggataac
    18961 gatgtggaat gatttctttt atttcttgta tgttcattgt tttccctctt tcctgctttg
    19021 cttatttttg ctgaatccta aagagtggct gtccatattc gacaactgac tcgttttcta
    19081 caaggatttc tgtgatcact ccgtcggcct cactagttat ctcattcatc agtttcatcg
    19141 cttcaataat gcagataact tctcctttgg caacttgatc acctactttt ttgaaagctg
    19201 gtttgtcggg cgctggttgc agataaacga ttcccacgat tggcgaaaca acctcgattc
    19261 catcaaatac tgccgattct ttttctttca ttatttctgg agcagttgtt gcttgttcag
    19321 gtatgacatt gactggctcc gaaactggca acgtttcgtt tgtttgaacc atattcatgc
    19381 ctcgacttgt tttattttta ttcatataca attcaaattg accttcacgc aaatcgaatt
    19441 ccgttagcga ggattgatca aattgactga ctaattctct gatttcattg atatccaaaa
    19501 ttattcctcc cagcgtttca tgcacagaac cgcattatgt ccgccaaacc ctaatgaatt
    19561 actcattgca taagtaaaac ttgcaggttt gctttcgttt ttgacaactg tcaagtcaat
    19621 ctcaggatct tgtttttcta cattgatcgt aggtgggata aattgatgtt ctaatgccag
    19681 caaagttgcc aaggcttcga tcccgccggc tgctcccaat aaatgtccag tcatcgattt
    19741 cgtgctgctg acgtaagtat ctctgaaatt ttcacctaat gcgatttgga ttgcttttgc
    19801 ttctgcctgg tcattggctg gtgtacttgt tccgtgagca ttgatatatc cgacttgttc
    19861 cggctgtaca ccagcttctt ccatcgcaag cttcattgct ttagatgcac cagaaccatc
    19921 tggagtagga gctgtcatat ggtaagcgtc acagtttgca ccgtatccaa cgatttctcc
    19981 atagattttg gcaccgcgag cttgtgcatg ttctaaagat tcaagaacta gaacgcctgc
    20041 tccttcaccc atcacaaaac cattccgatt ttcgtcaaac ggaatcgaac cacgattagg
    20101 atcagttgat tctgagagtg ctgttaaagc tgcaaatcca gcaatcccca tctcacaaat
    20161 cgttgcttct gttcctccag caagaatgac atcagaatag ccatgtttga tgttacggaa
    20221 tgcttcccca attgaattcg ttccgctagc acaagctgtt acgatagctg tacaaatacc
    20281 ttttgcacct acacgcaaag caatatttcc agctgccatg ttggcaatcg ccattggtac
    20341 gaacattgga gaaactcgtt ttgcaccttt ttcatgtaga cgaataactt ggttttcgat
    20401 tgttggaaga ccaccgatcc cagatccgat gatgacgcca aaccggtctt gattcatttt
    20461 ttctttatct aaaccgctca tctccattgc ttctaaagca gcgtagattc catagatcga
    20521 aaacatatcc attcgtttgc tatctttttt aataaaatat ttatcgtaag ggaaatcttt
    20581 gacttcaccc gctaaggtaa tccctgtttc tgaagcatca aatttagtga tcggtgcgat
    20641 gccattcgtc ccctctttta agctattcaa aaagctgtct gcgtcatttc caataggtga
    20701 agtgactcca tagccagtaa ttaccactcg attcatttgt ttgctctcct tttcttatcc
    20761 gtgcatgacc aatccgccat cgacattgat gacttgtccg gtgatatatg gattttgtgc
    20821 taagaaaact gctgtttgtg caatatcttc tacttgtccg aaacgctgca tcggaatttg
    20881 cttttccgct tgttccttga ctttgtctgc taaaacttcc gtcatatcag ttgtgatgaa
    20941 tcctggcgca atggcattac atgtaatgcc tctagttgca gcttctcgtg ccacagattt
    21001 tgttaatcct actacgccag ctttactagc tgcataattt gcttgaccaa tatttccaat
    21061 caacccagat acactagaga gattaatgat ggccccttct cgctgcttca tcattttttt
    21121 caatacgtgc tgcgtcatat tgaaggttcc aatcaaattg atatccagac attttttgaa
    21181 atcttctgca tccattcgca tcacaagttt gtcatttgtg attccggcat tgtttactaa
    21241 cacatggatc gatccaagct tttcttctgc ttctttgatc atttgtcccg ctttctcata
    21301 atcagagatg tcaccggaaa ctcctacgca ttttacaccg aatgcttcga tttcttctat
    21361 cttttctttt ggaatctctc cgcgaccatt caaaatgata tttgctccag cttttgcaaa
    21421 agctaaggcc atcgctttgc cgattcctct tgtactacct gtgataaata cattttttcc
    21481 ttttacatcc ataacgttcc tccttatagt attgctattg tttcatcaaa tgtctgctta
    21541 ttctcaacac gcagaactgg tattgtttta tcgatttttt tcataaatcc gcttaatact
    21601 tttccggggc cgacttcgat gacttgttcg atgccgattg tttttaactt atggatactc
    21661 tcatagaaac gaacaggttg catgacttgc tgttcaagta gtcccgcgat tgtttctttc
    21721 ttcattattt ccgttgttgt gttgcttatg ataggaaaag aaggttcaga gaattgaatc
    21781 tgacttaggt ccttcgccag tttttttgct gccggttcta aaatagctgt atgaaaaggc
    21841 ccgctgacat ttagagggat cattcttttg aacccttttt cttttaatag taaaacagct
    21901 tcgtctactg ctttttcttc gccaccaatc acgatctgct gaggtgtatt ataatttgca
    21961 ggagatacga tgccgtactt gctagcttca tgacagcttt cctcgatcgt ttcaatcggc
    22021 gcattcatca ctgcaaccat tttcccgctt ccagctgggg cagcttctgt catataagcg
    22081 cctctttttg ctactaacgc aactgcttca gtgaaggata gcgcattact agctactaat
    22141 gccgaatatt ctcctaaact cagtcctaaa gctgcatctg ggatgattcc atgctccttc
    22201 aataagcgat aatacgcgat gctgactgtt agaatagctg gctgtgtata ttgcgtctga
    22261 tccaaacgtt cattttctgt aaagcaaagt tcagccatat cgtagccgag aatctcactt
    22321 gcttcatcaa atgtctgctt tacaacggct tcttcatata aatcttttcc cataccttga
    22381 tattgtgcac cttggccact aaataagaat gctgttttca tgtttttctc caatatatcc
    22441 agaatatatg tttgattctt cctattcaaa aaggccgaga cattcctatt tcaggaaatg
    22501 tcccagcccc caacctaatt ttaatgatta tgcagtttgt ttttctacgt aagtcactaa
    22561 atcttgaacc gttttgattc cgtcttctgt ttcgattttc acgtcaaatt catcttcaat
    22621 ttcattgatg atttggaata aatccaagct gtcagcttct aagtcttctt ggatgtcagt
    22681 agtcaatttg atttcttcag tttcttttcc taattcttct gcgatgattt cttgaatttt
    22741 ttcgaatacc ataataatat attcctccga tattgtttgc tttttatttt tataatttaa
    22801 cagtctacaa ctccatgaga atacttcccc atgttaaacc tccgccatag cctgtaaata
    22861 ttactttctg ctgttttcct aaggtgatct ttccactaga aactgcttca tccaataaga
    22921 tagggatgct tgcagcagat gtattcccat atttatccat attggtcagg aacttttctt
    22981 gcggcatctt tacttttcgg gcaattttct caataattct gaggtttgcc tgatgcaaaa
    23041 gcagataatc aactggtttg tctttcatga cttcttggat attgtttgca acgtctcgta
    23101 cggcaaaatc aaaaatatct ctgccagtca tttgcaaata atacgaacct tctgaatctt
    23161 ctgaatagaa cggattttta ttttgctggt agccagcggt caatgagcta cttctggtac
    23221 cgtcagctgc taatttttct ttcagcaatt ttttctgtgg attcgcttct aagagaatcc
    23281 cacctgctcc atcgccaaac aacacagcag tcgtacgatc agaccaatcg attagcttag
    23341 atagtgtttc accaccaatc accagtccct tagttgagcc gcagcggatc attttttcag
    23401 ccatgcttaa cgcataaaca aatcctgagc acgcagcact gatatcaaaa gcgatagcat
    23461 gagttgctcc caatttccct tgtacttgtg ctgctacaga tggtgtcgtg taatcgggcg
    23521 acattgttgc tactaaaata aaatccaaat ctttagggtt tagatttttc tgttttatca
    23581 atttttccgc cactaaaatg cataaatcag aagtctcctg atttgttaca catcttcgtt
    23641 cacgaatacc cgtccttgac gaaatccatt catcagaggt atccatcatc ttggaaagat
    23701 cattattagt aataatcttt tcaggaagga cgctggctgt tgcagtaatc attccaaatt
    23761 gttccattaa atatcctcac ttatagtctt gcaagaagtc gtgcaagttt ttcagtgcat
    23821 ccagcaaggc atgctgttcc tccgtagcca ttccgtctaa gatgttcttg accatttcac
    23881 gatgaaaatg ctgatggacc cgaaatagta actttccttt tttcgttagt cccaacttta
    23941 caacgcggcg gtcatcttca ctgcggatac gttcgacata gccttttttt actaacttgt
    24001 taatagcagt ggtcaaggtc ccaacagtaa ttgatagttc tttggctact tctgaagttg
    24061 tttttttctt gtacatcccg attgcctcga tcgtgtgcat ctctgtgatt gacagatctt
    24121 tgaattgaga ttttttcagc tcagactctt cgattgtcaa aatatcattg aagacactaa
    24181 caagataatc atttactgtt tttaaatctg gttccatgtt ccaccgtcca ctaattagtt
    24241 tgattatcaa atcttttgat gttcaaacta tatcttaact tttttcaaaa tgcaacctta
    24301 aaagatcatt tttttactat atgagctttt tttaagattt tactcattta aaacaactga
    24361 taaatcagca tttataattt cttttattag aaaaatcatc tatctcacat attttgatta
    24421 tcaaagtatt ttctgtgaac agaactatag aattccctaa aacttgtcca ttatttcaaa
    24481 atttgttata gtctttttat tcaaagcgta aaaggagatc ctatgttaaa agaaaaaatg
    24541 aaaactctcc ccatgctgcc gggtgtctat cttatgaaag accgagatgg taaggtcatc
    24601 tatgttggta aagcaaaacg gctcaaaaat agagtaagca gctattttca tcagaataaa
    24661 cagcattcaa aaaaagtatt acgtatgatt catcatataa cagattttga tttcgtcgta
    24721 gtagacacgg aattagatgc tttattgctc gagtgtcaat tgatccaaca ttaccgtcct
    24781 ttttataacc gacaaatgaa ttatttcagt aattataatt atgtacatat taccaataag
    24841 ggatttgtat taacagatac tcctacggct cgaacatacg ggccttttcg tctctataaa
    24901 aaaatgccgt ctattttgcg tataatggaa gaaacttatc aaatgccttg gttgtctgaa
    24961 attagtttgt tagctttgcg agtccagctt cctgacctac aggaaatgac ttttgaacag
    25021 aaaaaaaagg aactccaagg gctgtttcaa ggccgaaata aaaagctact gacttacttg
    25081 aaaaaaagac aacaacattt catctatcag ttgaatttcg aaaaagccgg tatgcttcaa
    25141 aaagatatcg aattagttac ttattttatt agacggatcc aggaacaaaa gcagttttta
    25201 agaacaccat cgctcacctt cagcatgcca ttagcagcag atgagagtca gaaaaagcac
    25261 tacctcgttt gttatggtca acttgcagaa acaatgatta cctctggtga cgtttctcct
    25321 gacttctatt atgaaaagaa agaagctcat ttatctttga aacgtcaatt gtcaaaagaa
    25381 gaaatcgatc ctgtacaaat cttgatcagt taccgcaaaa aattagaaaa agaacagttt
    25441 gaaattgaac tgttaaacaa aaaagaagct gaaaagcaac taaattagtt gcttctcggc
    25501 ttcttttagg catcttcaac ttcaaatgtc aattatccta aaatttattg gattaagtca
    25561 tagatttcca tcgctacgat atcgatatta tcaaattcgt attgctgatg agtatctgtt
    25621 tcagttaatt caaatgtatc ggtcgcttta tcataagtta ctgtacactt ctctacgcct
    25681 tctttttcaa aacggcgaac ttgcagttca ttatctgctg actcgaccat agcctccagt
    25741 cgttttatga ttgcgactaa ttgtgaatgt gtcatcggag gtcctccttt tcttatttct
    25801 gttatattgt atcaaaagca tagcctactt gcattgattt tctctaaaaa aactcgtttt
    25861 ttatgatttt ttttctggta tttttccttc aggccaccaa agtttgatca aagcttgggt
    25921 tccgtcattc tcaaaacctt tatctgccaa ctcttcatat agtttcaatg cttgggtagt
    25981 tgctggcaat acaagatcca ttttttctgc ttcttctaat gcaatcttta aatctttgat
    26041 aaaatgtttg acaaaaaaac caggtgtgta atcttctttt aaaatacgag gagaataatt
    26101 gcttaaagac cagttagctg cacttccacc tgaaagcgtc tcaatcactt tctttaaatc
    26161 aagtccgttt ttttgtgcat agacaagcat ttccgtcatt cctgtcatcg tacctgcaat
    26221 catgatctga ttagccattt ttgtatgctg acctttccca gcagaaccat gcaatgtaaa
    26281 tgtcgtacca aattctttga ataaaggcag tacttgatca taaacggctt cttctccacc
    26341 gaccatgatc gtcagtgtac cattctttgc tcctaagtca ccaccggata ccggtgcatc
    26401 taacgcatct gcgccttttt cttttgctgt ttttgcaatt ttttctgcca ggcttggtgt
    26461 acttgtagtc aaatcaacta aaatatgtcc tgagatatct gcagaaaaaa tccccgactg
    26521 tccatagtag atttcttcta catctttggg gtaacctacc attgtaaaga gaatattact
    26581 ttgttctgct accgcttttg gtgtatctgc ccagatagct ccttctgtta ctaaaggatc
    26641 agcttttgct tttgtccgat tatagacagc tacttcgtgt cctgcttcta gtagatggcg
    26701 tgcgacagca cttcccatga cgcctgttcc gataaaacca agtttcattt tttcgacctc
    26761 ctaaaaatca aaaatccttg cttctatgct agtatacgct agaaacaagg attttttcat
    26821 aaaaaatgtt tgaattttat cttttaaatg aatttaattt tattttgatt cgttcaatcg
    26881 agtcttcttc ttcttttctt cgcatctctt cttcatgata aacaaccatg tcttgataaa
    26941 attcgatcat agcttcgccg aaatgtgtag atgaaatatc ataaagttta gcttctaaaa
    27001 cttttggatc tttaggaact tcactggaaa tataatcaat aagtgctggt gcaaagtctt
    27061 cgtcggtttc aaaagttttc cctaatgaag gatgatcgaa caatcggttc aaataagcat
    27121 ttccttccac gacacaaggt gttccggctg ccatcgcttc tgtataagta agcccttgtg
    27181 tttctgaagt agaagcactg acaaaataat ctgccgcttt ataataaagt gctacatcat
    27241 tgttgtccac ttctcctgtg aactgcacaa attcttctaa ctgcagttct gagatcaatt
    27301 cctctaactc ttctacataa ggtccttttc ctacgataac taatctggcg ttaggataag
    27361 cggagatgac ctgaggaaac ccattaatca aggcttggat atttttctca taagaaatcc
    27421 tgcttaaaga aagaatcatc aaatggtttt cctgaagacc tagtgactcc cttaatttgc
    27481 tgatatcctg ctgagtgata tcagaacgtt tgaatttttc aatgtcgata ccagtaggaa
    27541 tcacgcgaag cggtgctatt acaccatagc tgcgtaatgt atcaataaca cgttcacttg
    27601 gacaaactac acctgtcgta tgatttgcaa ataatctaga caagtatttt acatgggatt
    27661 gcctgatcac ttttccttta ccgatataat gaaggtagtc ttcatacatc gtatggtaag
    27721 tatggatcag aggtattttc aacttcttag ctaccatctt cccaagtatc cctgctccga
    27781 attctgtatg ggtatgaata agatctagtt ctagttcttt ggcaaccaaa taagcatacc
    27841 acatgcctct aacaacaact cttcgatcct tgaaagaaat aaatggtaca cttggcattc
    27901 gaatcacatc tttttccaac ttatccgcat taggatcggt cgttgtaaaa atatagactt
    27961 catgcccatg tctttctaat tcttgtttta atgttttgat cgatgtagca actccgctga
    28021 cttgcggaaa gtaggtatcg gtaaaaaagc cgattttcat gtttttcgcc tccaaactag
    28081 tccttgacct gatttacttt ttttaatttg ctagagactt tttcattcag tacactttcg
    28141 tatacatttt taagttcttc accgatttta ttgatacttc gctcttttgc tgtttgataa
    28201 ccggcttgtg tcgtactcgg tagttcttga ttggtaatct gttggatcag tcggataaat
    28261 tcttcgtttg tcttccccat atagcagttc ttgctatctt ctaaccagcc attatacact
    28321 ggaatatctc gaacaagtac gttttgtttg cttgctaaag cttctaaaac aacgatccct
    28381 tctgtctctt cataagaagg gaaaaagaat agatctgcac ctgaatacgc accttctatg
    28441 atctctccac gaatgtaacc aggaaacagg acattttcag gatgatcttc ttttacaatt
    28501 ttccggatgt tccgaggaat cgagtacatg ggaacatgac caaaccaaat aaatgtgtat
    28561 tcgggcatct tcttagcaat ttctacgaaa tcaatgattc ctttacgttc gaaaaacaaa
    28621 ccgacacaaa tgattacttt ttgatccgga gacagtttga aatattctct gaacttttgt
    28681 tctttcattg gatcagggtg atatttctct aagtcgatcc cattggaaat agcttgaatc
    28741 ggcacacgga taccatagct ttccaacaac tgttttgaat aaggtgttgg cgtgatcaga
    28801 tagtccgctt tttggtacaa tcctaccaga tattttttta cgataggaga aagctggttc
    28861 gatctgataa aggaatttcg gaaatcttcc tctgtagaat gcgcatgata gacaactttt
    28921 tttccttctc ttctggcttt attgaccata ttatgactat tgattccgta tgtattgatg
    28981 tgcaggatgt cataatcttc tttttcatct agtgtataag agataccgac ttccgtcaga
    29041 gcacgttttt gatgatcaag cgcacgcccg attccagatt ttgcaagcat cttttcactt
    29101 tcaaaatata ataatacctt caccttacgt cccccttcac ttatatagta taacatagcc
    29161 tacaaactgt cactcaaact taagccctat ttttgtctat tcttactgac aaaaacgttt
    29221 tcttaaaaaa gaacaaaaaa actggcgtag ctcttttaca agccacacca gcttttgata
    29281 cgttgtttat tttacatatt catgaacaag ttcaacgact tcttccatca tatcgcattc
    29341 tttcaatgca cgatcagcaa gttcagccat tttcgctgtg tccaagcgtt tcattaaact
    29401 acgcgtttta agaatagatg tcgcactcat tgagaactca tctagaccca tacctactag
    29461 caatggaaca gctgtttgat ctccagccat ttctccacac atacctgccc attttccttc
    29521 agcgtgtgct gcatcaatta catttttgat caaacgtaaa attgatgggt tatatggttg
    29581 gtacaagtaa gaaacgcgtt cgttcatacg gtctgctgcc attgtgtatt gaatcaaatc
    29641 gttcgtacct acagagaaga aatctacttc ttttgcaaac ttgtctgcta agactgctgc
    29701 tgctggaatc tcgatcatga tgccgacttg gatcgtatca gatacttcct tgccttcact
    29761 tatcaatttt tgtttttctt cttcaaagat cgcttttgct gcgcggaatt ctttgagtgt
    29821 agctaccata gggaacatga tacgtaaatt accatgaaca gatgcacgaa gcaatgcacg
    29881 catttgtgta cggaacattt cgtcgccttg ttcagataaa ctgatacgca atgcacgata
    29941 tcctaagaat ggattcattt catgaggtaa ttgcagatat ggtagttctt tatctccacc
    30001 gatgtccatt gtacgaacaa ctacaggttt tccttccata ccttctaata cagctttgta
    30061 agcttcatat tggtcatctt ctgttgggaa gtctggagaa tccatataca ggaattcagt
    30121 acggtacaga ccaactgctt ctccaccatt attatggaca ccaactagat cttttggtgt
    30181 tccgatgttt gcagctaatt caaaatgctt gccgtcagct gtgacagttt ctgcattttt
    30241 taatttttcc cattctgctt tttgtgctgc gtaatctgca cctgcttttt caaattcagc
    30301 tttttgttca tctgtaggat cgatgattac atcgccttcg atcccgttga cagccaaaat
    30361 atcgccttct ttgactttag cagtaatttc ttttgtccca acgattgctg gaatttctaa
    30421 agaacgtgcc atgatagcag aatgtgaagt acgtccacca atgtctgtta caaacgcttt
    30481 tacaaaattg cgatctaatt gtgctgtatc acttggagtc aagtcatgtg caacaacgac
    30541 cacttcttcg ttgatcattg atggatttgg taaagtaacg cctaataagt gcgctaaaat
    30601 acgtttagca acgtcacgaa tatctgcagc acgctcttgc atataagcat tatcttccat
    30661 tgcttcgaac ataccgatat acatatccgt tacttctttt agcgctgatt cagcatttac
    30721 gctgttgtct ttaatatttt gcttgatttg acctaccatt tctggatctg aaagaaccat
    30781 caaatgggca tcaaatactt gcgcttctgc ttcacctaag ctttgcgctg ctttttcacg
    30841 aatttgctgc aattcttcag tagatttagc taatgcagca tccaaacgag cttcttcagc
    30901 cgcagtatct tctactgttg ccttactgaa tgttaaatcc ggttgaacta gcaggtaagc
    30961 ttttgcaacg gctacaccgt cactagcggc aatccctttt agcatttcaa ccattattca
    31021 gataagcctt ctttcttcat tgtttcaacg attgctgcca ttgcatcagc ttcgtcagca
    31081 ccttctgcag taatagtaac atcagaacct tgacctacac ctaaagacat aacgcccatg
    31141 attgatttca agtttactga tttaccttta tactctaagt ttacatcaga gttaaatttg
    31201 cttgctgttt gtactaatag tgtagctgga cgagcgtgga tcccagtttc tgctactacg
    31261 tgaaattctt tcttttccat attaatcggt ctcctttaag tgagtgttgt ttttatgtga
    31321 gggttttctt ttttagtaat tcagagaatc ctaacaaatg ccaccctttc atctgtaaag
    31381 attaacattt tttttcgtta gatacaacag ttttcattca atttcagata aaagtattca
    31441 aattattccg gattcttttt catccttttc ttcacatttt ataacaaacg tgtttatttc
    31501 ctttttcttg tcgctttctc ttctcctgac gtttatcatt ctttcctttg accctctttg
    31561 ttttcatatg aaacgaatta cttgcttccc tttttatttt tagtataata agagtcaaag
    31621 gtcaggaatg gtcaatagag atttcacctt ttctacctca taaatctctt aaaaaactag
    31681 gggttattct tttacctcat gaaaaacgag atgtaaaata tggatgtacc catttttgtg
    31741 aaaggacgtg aatgattcat gctttgtcaa aactgcggca agaatgaggc aacgattcac
    31801 ttgtatgcca ctgtcaatgg tcagcggaca caactcgatt actgtcagag ctgttatcaa
    31861 aaaatcaaaa atcaacaaaa tggaggtctg actaatatgg cccaaaatga tccatttgga
    31921 tttggcagtt tggacgatct tttccgttcc atgtctcgcc aaatgcaaca gcaaggaaat
    31981 tatgagcaaa caccaccaac acaatttggc ggaaacaaca acttcaatgg tggtcagcca
    32041 cctcaaggca atacagaagg tttattggga gaatacggaa tcaatatcac agaacaagca
    32101 cgacaaggtg atatcgatcc tgtgatcgga cgcgatgacg aaatcaaacg agtcattgaa
    32161 attttaaatc gccgaaccaa gaacaatcct gtcttgattg gagaaccagg tgttggtaaa
    32221 acagcagttg ttgaaggttt agcacaaaaa atcgtagatg gtgatgtacc gcaaaaatta
    32281 atggacaaag aagtcattcg tttagatgtc gtatctttag tccaaggtac tggtatacga
    32341 ggacaatttg aagaacgtat gcaaaaattg attgaagaga tccgtcaagc agaaaatgtg
    32401 atcctattca tagatgaagt tcacgaaatc gtcggtgctg gttctgctgg tgatggaaat
    32461 atggatgctg gtaatatttt aaaaccagct ttagctcgag gagaattgca aatggttggt
    32521 gctactacct taaatgagta ccgcatcatc gaaaaagacg ctgctttaga acgtcgtatg
    32581 caacctgtac gggtagatga accaactgtc gaagaaacga tcagtatttt gaaaggtttg
    32641 caaaaacgtt atgaagacta tcatcatgta aaatatactg atgaggccat cgaagcagcc
    32701 gcaactttat ccaatcgtta cgtccaagat cgcttcttgc cggataaagc catcgatttg
    32761 ctagatgaaa caggttctaa gaaaaacttg acgatccaaa tcgttgatcc taaaacaatc
    32821 gagaaaaaac tgcaagaagc agaagaacaa aaagttttag cttctcgaga agaagatttc
    32881 gaaaaagcag cttattatcg cgatcagatc aataaacttc aaaaaatgaa agaacgtcag
    32941 ctcactgaag aggaaacacc tgtgattacc gaaaaagata tggaaaaaat cgttgaacaa
    33001 cggacaggta ttccagtggg tgaattaaaa gaaaaagaac agacacaact gaaaaactta
    33061 gcagatgact tgaaagctca tgtcatcgga caagataacg ctgtagatcg agtagcgaaa
    33121 gcgattcgcc gaaaccgtgt tggattaaac aaacagaatc gtccaatcgg ctccttctta
    33181 tttgttggac caactggtgt aggtaaaaca gagcttgcga aacaacttgc ctacgaacta
    33241 ttcggttcac aagattcaat gattcgtttc gatatgtctg aatatatgga aaaacatagt
    33301 gtctctaaat tgattggttc tcctccaggt tatgtcggat acgaagaagc tggtcaatta
    33361 acagaaaaag tacggagaaa tccttacagt cttgtcttgt tagatgaagt agaaaaagct
    33421 catccagatg ttttgcatat gttcttgcaa atcttagatg atggtcgatt gacagatgca
    33481 caaggaagaa cggtcagctt taaagatacg atcatcatta tgacaagtaa tgccggaact
    33541 ggtaaagtag aagcaaacgt tggttttggt gcggcacgcg aaggtgttac tcgttctgta
    33601 ttgaaccaat taaacaacta ctttacacca gaatttctga accgttttga cgggatcatc
    33661 gaattcagtg cattatcaaa agaaaacttg atgacaatcg tcacactaat gctagacgat
    33721 gtcaaccaaa tgctggcagc acagcaactt cacatcgaag ttcctacgaa tgtcaaagaa
    33781 aaattagttg acttaggcta tgatccatct atgggtgctc gtcctcttcg acgcacgatc
    33841 caagaacaaa tcgaagatgg tatcgctgaa ttttatcttg atcacccttc tatccatgag
    33901 ttgaaagcaa aactggataa agatggaaaa atcatcgtta cttctaaacc agaacgtttg
    33961 gctaaagaat cagccgaaga aacggctgaa taaatccagt tttatagcgt gagacggtat
    34021 ttctttgaga aatgccgtct cattcttttt tcagaaaagt caaaatactg ttcattttat
    34081 aaaaaagaaa ttataataag agaaacaagc aattaaaaat acataaaaga ggtgagcgcc
    34141 atgaaattgg taaatgtaac aaacagccat tcccgtcttg tattaaacca gcttgaaaac
    34201 actgatgccc atctagtcaa ggtctacaca gccggaaata ccactattgt ctacactgaa
    34261 gcccctgaac ataatgaaat tctgctgatc aatgacaaac gtaaaatcca gccgaaagaa
    34321 atcgaagatg ctaaaaatta tttcttagat aaaatcaaag acgccgttta ccacgaggat
    34381 gaaatcaaag taatcgaatt ggcaggcctt gttgaaatct cgattccaaa acatgaatta
    34441 ggcgctacat tagccgtgta aacaaatttt gaacataata attaaagagc gtgggacaaa
    34501 agtaaagaac acttttgtct cacgctctaa acacgtataa acggcgaaag cagaagcaac
    34561 tccttcggaa ataagctgaa attcacgaaa attgcttttc aaat
//
LOCUS       DAZUJR010000021        34532 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.021, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000021 DAZUJR010000000
VERSION     DAZUJR010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34532)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34532)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34532
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.021"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            5..478
                     /locus_tag="ACG804_000947"
     CDS             5..478
                     /locus_tag="ACG804_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HFS4831895.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            487..714
                     /locus_tag="ACG804_000948"
     CDS             487..714
                     /locus_tag="ACG804_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4831896.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            1350..1721
                     /locus_tag="ACG804_000949"
     CDS             1350..1721
                     /locus_tag="ACG804_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831897.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
     gene            complement(1977..2219)
                     /locus_tag="ACG804_000950"
     CDS             complement(1977..2219)
                     /locus_tag="ACG804_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFS4831898.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(2251..3153)
                     /locus_tag="ACG804_000951"
     CDS             complement(2251..3153)
                     /locus_tag="ACG804_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFS4831899.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            complement(3166..3354)
                     /locus_tag="ACG804_000952"
     CDS             complement(3166..3354)
                     /locus_tag="ACG804_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HFS4831900.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            complement(3368..3931)
                     /gene="amaP"
                     /locus_tag="ACG804_000953"
     CDS             complement(3368..3931)
                     /gene="amaP"
                     /locus_tag="ACG804_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HFS4831901.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            complement(3969..4862)
                     /locus_tag="ACG804_000954"
     CDS             complement(3969..4862)
                     /locus_tag="ACG804_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFS4831902.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKVAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            complement(4940..5863)
                     /locus_tag="ACG804_000955"
     CDS             complement(4940..5863)
                     /locus_tag="ACG804_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFS4831903.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            complement(5912..6262)
                     /locus_tag="ACG804_000956"
     CDS             complement(5912..6262)
                     /locus_tag="ACG804_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFS4831904.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            complement(6295..7197)
                     /locus_tag="ACG804_000957"
     CDS             complement(6295..7197)
                     /locus_tag="ACG804_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HFS4831905.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            complement(7190..8047)
                     /locus_tag="ACG804_000958"
     CDS             complement(7190..8047)
                     /locus_tag="ACG804_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HFS4831906.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            8381..9190
                     /locus_tag="ACG804_000959"
     CDS             8381..9190
                     /locus_tag="ACG804_000959"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFS4831907.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            9230..9727
                     /locus_tag="ACG804_000960"
     CDS             9230..9727
                     /locus_tag="ACG804_000960"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase family cysteine hydrolase"
                     /protein_id="HFS4831908.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(10112..10185)
                     /locus_tag="ACG804_000961"
     tRNA            complement(10112..10185)
                     /locus_tag="ACG804_000961"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10149..10151),aa:Ile,seq:cat)
     gene            10372..10695
                     /locus_tag="ACG804_000962"
     CDS             10372..10695
                     /locus_tag="ACG804_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831909.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            10859..11113
                     /locus_tag="ACG804_000963"
     CDS             10859..11113
                     /locus_tag="ACG804_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831910.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            11183..11428
                     /locus_tag="ACG804_000964"
     CDS             11183..11428
                     /locus_tag="ACG804_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4831911.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            11504..11869
                     /locus_tag="ACG804_000965"
     CDS             11504..11869
                     /locus_tag="ACG804_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02328 family protein"
                     /protein_id="HFS4831912.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(11930..12493)
                     /locus_tag="ACG804_000966"
     CDS             complement(11930..12493)
                     /locus_tag="ACG804_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831913.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
     gene            complement(13220..13933)
                     /locus_tag="ACG804_000967"
     CDS             complement(13220..13933)
                     /locus_tag="ACG804_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFS4831914.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            complement(13926..15011)
                     /gene="uxuA"
                     /locus_tag="ACG804_000968"
     CDS             complement(13926..15011)
                     /gene="uxuA"
                     /locus_tag="ACG804_000968"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFS4831915.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            complement(15028..15471)
                     /locus_tag="ACG804_000969"
     CDS             complement(15028..15471)
                     /locus_tag="ACG804_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFS4831916.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            complement(15505..15858)
                     /locus_tag="ACG804_000970"
     CDS             complement(15505..15858)
                     /locus_tag="ACG804_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831917.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            complement(15970..16371)
                     /locus_tag="ACG804_000971"
     CDS             complement(15970..16371)
                     /locus_tag="ACG804_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831918.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            complement(16408..16917)
                     /locus_tag="ACG804_000972"
     CDS             complement(16408..16917)
                     /locus_tag="ACG804_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HFS4831919.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            complement(16939..17796)
                     /locus_tag="ACG804_000973"
     CDS             complement(16939..17796)
                     /locus_tag="ACG804_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFS4831920.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLKQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            complement(17814..18647)
                     /locus_tag="ACG804_000974"
     CDS             complement(17814..18647)
                     /locus_tag="ACG804_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFS4831921.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            complement(18661..19458)
                     /locus_tag="ACG804_000975"
     CDS             complement(18661..19458)
                     /locus_tag="ACG804_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HFS4831922.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLSSEFKQLSEIIFAVAGLVGGLGDKYARNVAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            complement(19491..19775)
                     /locus_tag="ACG804_000976"
     CDS             complement(19491..19775)
                     /locus_tag="ACG804_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HFS4831923.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            complement(19772..20773)
                     /locus_tag="ACG804_000977"
     CDS             complement(19772..20773)
                     /locus_tag="ACG804_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-isomer specific 2-hydroxyacid dehydrogenase
                     family protein"
                     /protein_id="HFS4831924.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFNVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMCEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            complement(20775..21677)
                     /gene="gnd"
                     /locus_tag="ACG804_000978"
     CDS             complement(20775..21677)
                     /gene="gnd"
                     /locus_tag="ACG804_000978"
                     /EC_number="1.1.1.343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphogluconate dehydrogenase
                     (NAD(+)-dependent, decarboxylating)"
                     /protein_id="HFS4831925.1"
                     /translation="MEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDI
                     PAYQEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSI
                     RRAEEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLY
                     AGASGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWL
                     MEIMEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEED
                     SFSAKVVSALRNGFGGHEIVEKGE"
     gene            21841..22689
                     /locus_tag="ACG804_000979"
     CDS             21841..22689
                     /locus_tag="ACG804_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFS4831926.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            23335..23541
                     /locus_tag="ACG804_000980"
     CDS             23335..23541
                     /locus_tag="ACG804_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HFS4831927.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(23743..24744)
                     /locus_tag="ACG804_000981"
     CDS             complement(23743..24744)
                     /locus_tag="ACG804_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFS4831928.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(24749..26662)
                     /locus_tag="ACG804_000982"
     CDS             complement(24749..26662)
                     /locus_tag="ACG804_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFS4831929.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            complement(26830..27336)
                     /locus_tag="ACG804_000983"
     CDS             complement(26830..27336)
                     /locus_tag="ACG804_000983"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HFS4831930.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            27496..27936
                     /locus_tag="ACG804_000984"
     CDS             27496..27936
                     /locus_tag="ACG804_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFS4831931.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            complement(27962..29077)
                     /locus_tag="ACG804_000985"
     CDS             complement(27962..29077)
                     /locus_tag="ACG804_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831932.1"
                     /translation="MKNYHLSCSLKKGNPIEGEEYRIRYFFHLMYWQSFDENHSDILS
                     SIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSITYVPEEMNKFVHPL
                     ITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYLEEDLLDTPDKVQES
                     WGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGTKKKVDAFGKSAEDR
                     DFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCMLVRDIFIKHEQPVIF
                     YIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYPIDKKAYDQTNTQIF
                     YWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(29122..29478)
                     /locus_tag="ACG804_000986"
     CDS             complement(29122..29478)
                     /locus_tag="ACG804_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831933.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            complement(29776..30750)
                     /gene="sgrA"
                     /locus_tag="ACG804_000987"
     CDS             complement(29776..30750)
                     /gene="sgrA"
                     /locus_tag="ACG804_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HFS4831934.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            complement(30946..31785)
                     /locus_tag="ACG804_000988"
     CDS             complement(30946..31785)
                     /locus_tag="ACG804_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFS4831935.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            31970..32857
                     /locus_tag="ACG804_000989"
     CDS             31970..32857
                     /locus_tag="ACG804_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HFS4831936.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLIDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            complement(33451..34146)
                     /locus_tag="ACG804_000990"
     CDS             complement(33451..34146)
                     /locus_tag="ACG804_000990"
                     /EC_number="4.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HFS4831937.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(34130..34528)
                     /locus_tag="ACG804_000991"
     CDS             complement(34130..34528)
                     /locus_tag="ACG804_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HFS4831938.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
BASE COUNT        10097 a         6915 c         5493 g        12027 t
ORIGIN      
        1 aaaaatgaaa tttaaaacat tgctattaaa atttgtcgtt ttaggtataa gtgccgtatt
       61 tattttgttc ggcgtacttt tttatactca gatcgctaca agcgaaaaag gattcaattt
      121 tgattggcag accacattat ttgtttctgt catttacttt gcccttctcc tagggatcgt
      181 tattgcttat ttcttattga aactattgaa aaaaatcgaa gataaccaag ctttttccac
      241 tcaaagctta aacatactaa aaaaaatcga acgaaccatt ttgtttattg gtttcgcctt
      301 ttttggctta cttcctaaat ttatgaaagt agcggattta gacgatgctc caggtttgat
      361 gttggtagga atcgctgtcg tattcattcc ttttgcagta tacacattaa caagcgtgct
      421 ggaaaaactg cttgaacatg cgattttact taagacagat catgatttga cagtgtgagg
      481 tgcgacatgg caattatcgt taatttagat gtagtattag ctcaaaaaaa aatgagtgtg
      541 actgaattga gtgagaaagt gggcattacg atggcaaaca tctctattct aaaaaatgga
      601 aaagcaaaag ccatccgttt ttccactctc gaaaaaatct gccaagtttt ggagtgtcaa
      661 ccaggtgatt tgttgaccta taaaaatgac tcgaatacta taccagaaga ataaaataaa
      721 gtagaacaaa cagtaaataa aaaataatct gaatgataga tgtgtgagac ttttagaagt
      781 tatttacgtc tattattcag attttttatt tcgattgaat accgttttat ctataaataa
      841 gatatgtact gactcataca aagggggcct tttcttctcc atgtactatc acttttcctg
      901 atacaactgg tttcctgtta cgttgtagtt ggatctgctt ttagtataat actttattca
      961 ttccaccaga ctgatagcag tttgagcagt ctaaataatc atgtagtatt acaggccatt
     1021 ctgtttcata ccttgaagtg cttaaaactt cagctaatgg cccattgtgt taactcttac
     1081 tccattcttt tttagtaagc tcccatatat actgtaaagc cttctatata ttatgtcatg
     1141 ttgcttttta acatttacta tgtagttttg ataaaatgat ttgaataaca gtgatggaca
     1201 attctttttt atttttaaca ttattttgat aataatgatt atttatttaa aaatacatta
     1261 gataacattt gttacgacac gaaaaagctt cacaaacaaa tatcgttatt ttaaaatgag
     1321 ggcgaactca cacaattagg aggaatagta tgccatttat tgtttacttt tttctttcat
     1381 tactcgtgat ctatattcca ttaccaacat ttttcctgct cgtcaatcgt ctagcagagc
     1441 aacatgatac gattgctgct cttacgaaac tttgtttact tctatttgtt tgtctagatt
     1501 actttacgag ctattattgg ctaaaacaga caagagtaaa aaagagatat tatttcttcc
     1561 ttgtcttttt caatctcttt gagtttctga tccattgctt tttacttcat cagtatcata
     1621 cgatccattt gtggatcatc tgggttttca aagtggtcgt attattttgt atgttcacct
     1681 ttcctatctc aagaaaattt agggaggcat tgttttatta aagaagcttc tctgtatcaa
     1741 taaagacaca tttaaggaaa aacttttaaa aatctaattg ggaatttgcc cgcataaata
     1801 agaggctgtg acaaaagtct tgtcacagcc tcttattccg tataaacagt gttcaaaagc
     1861 ttgcatcttc gataatatgc ccaaccaaat gaaaaatatg agaagctatt tttgtttggc
     1921 tgttcttatt acttgatgaa gaacagcttt ttcacgacct ctttttaaaa gtctttttac
     1981 agttttcgag caaagaatga tacgattagt actaaaatga tggcaccaat caatgatggc
     2041 acgattgcca ttcctgcaat acttggtccc caagaaccta ataatgcttg accaagtgct
     2101 gatccaacta aacctgctac gacatttgca ataatcccca tcgaagaacc tttattcgtg
     2161 attgctcctg caattgctcc gataattcct ccgacgataa gtgaccaaat aaatcccatg
     2221 tttcgttcct cctaatgttt tacttcctta ttactgaacc cgtggttctg tattttcttt
     2281 tactttttgt gcgccgcttc cagctgctga ttttacttta tctgtttgat tcgaagcaaa
     2341 ttcaccggtt tttttcgctg cgtcagttac tttgtcttgc accgtttctt gatctttttc
     2401 aaattcttct tttgttttga tgtccactac gttagcgttg acttcgatca cttctaaatg
     2461 tgtcatattt tttacttctt tgccgattac ttcttgcatt tcttcaaaga ttttttcgat
     2521 atctttgcca tattccacaa tgacatccat atcaactgct acttgttttt taccgacttc
     2581 tgtttcgatc ccagccgtta cattatctgt attcacaagt tttcctgcca cattagagaa
     2641 gaaaccaccg tttgcagata ataaaccgtc tacttgttca attgcgattc cgatgatttt
     2701 ttgcacaact ttatcttcat aattcagctc accgcgcatt gaatcttcct gttcagaatc
     2761 atgctttcct tggttatttg tatgatcaga accaagtttt ccttgtccgt ttgtgtggtc
     2821 agaactaagt ttttcttgtg ctttcgcatg gtcagaagga tgtttttgct cttccacagg
     2881 tttagaagga tcgattgcat catgttgttc tggaacttta gattctggag ttcctggatg
     2941 atgaggtgca tgcttttctg catcatgttt cttctcttct actccttgtt gaacgttagg
     3001 gactactgga tctggatgtg cagatactgg tgctgttttg ttcttttcat cgttcacacc
     3061 atttgattgg tttggtgtcg ttgggtctgg atgtgcagac actggttttt ggttgttcat
     3121 tttattgtta ttatttttgt tattgttatt catggatgtt tcctcctaag atttaaaata
     3181 gtgatctaag attttcgttt gtttcagata aaaaccgata gcgacgccga tcgctgccat
     3241 gatcaagatc aataaggtct tgaaaaagcc cacggtgatc cataaaacgg ctaatatcaa
     3301 tccaagtacc ccaaagatga tagggagctt gtatgtcgaa aatagttctt tcatttttgg
     3361 tcccccccta ttctactcgt ttgcggtcat tgcttcgttt agctggttct tcaaagcctg
     3421 tgtatttcac cgatactttc actggctctt ttgttcccaa tatgtgttgt acttcatttt
     3481 cgatttcttt catcaatgtt cctgttttac caatgagtgc tgaagttcgt ttcaactccc
     3541 cttttacatt gacggcgatc ttgtttttcg ttgctttgac atttactttt ggtgaatgga
     3601 tgaattcatc ttcatgcaag tgagaacgaa ccattccttc aattgctttt ttatccaacg
     3661 tcaactcccc atcaccatgt ttcagtagaa agtttccgat tgtttttgga taaaacagga
     3721 aaacaagtaa cgtgataatt gtcaaaatag caaatgcaac ggcaagccaa aatacatatt
     3781 gttgcacgta tgaattagtg atggaaaaga atcgaaactt ctctagctga aaaggcaatg
     3841 gataggttgc acttaatagt atcgcaaaca aaagcacaga tagcaaaagt aatgttccga
     3901 tcactccgat cgtttttaca cctttattca ttttcgcacc tcctcatagg ggtgaaacga
     3961 tcaacttctt ataagttgat cgcttctcca ccagttactc cgtaaatttg ggctgtaaca
     4021 taacttgctt tattcgatgc taagaaaaca taaactggtg ctaattctcc tggctgacct
     4081 gcacgttcta gtaaactttg ctgaccaaat tcagggatcg aatcagaagg ttgtccttcg
     4141 tctagttgta atggtgtcca gattggacca ggtgctacac catttacacg gattccttta
     4201 ggtgcaagct gttttgctaa accgatcgta aagttagcga ttgaagcttt tgttgctgcg
     4261 taatctaata aatgttcgct tggattgaat gcttgaacag aagttgttgt tacgattgct
     4321 cctcctgctg ggatatgcgg aacagcttct ttcactaaag caaacatagc gatgatgttt
     4381 atcataaatg tgtctttgac ttgctcaagt ggtaactcag caatagactg acaagaaatt
     4441 tgctgtcctg cgtttagtac catcgtatct agcccgccaa gttcactcac ggctttatct
     4501 atgatttctt taggtgcttg ttcgtcacga agatcaaaag gtagtaagac aatcttacgt
     4561 cctgcaactt tcacgtattt tgctacttcc tctgcatctt tttcttctcc tgggaagaat
     4621 tgaagagcga tatctgcccc ttctctagca aatgcaatcg ctgctgcacg accgatccct
     4681 gaatctccac cagtgattag tacacggcgg ttttctagtt gattattgcc ttcataggat
     4741 tcttctccac aatcaggaac aggaatcata ttctgctgta aagctggtgt atcctgatct
     4801 tgtttaggaa atttctccgt atggtacaag tttcgcgggt cgattaattt tggttctgtc
     4861 attgctgtat tcctcctagt ttttaaattg tattgccaaa acaaatttct ttgtttgata
     4921 cctgttttaa atagattctt taatttgtat aatctttccg gtataaatgg taacctaaaa
     4981 ctactgctgc tatcaaagag ccaaagacta cgagtataaa gcctagagca gaacttttac
     5041 ccggtaatcc tcctgtattc attccccaaa tccctgcgaa caacgccgga acggaaatga
     5101 ttaatgcagc tgaatctaga tatttcatga tatgatttag attattgtcc atcatcccgt
     5161 tgaatagatc accaatactc tctaataaat ctcgatagat ctcgatcatt ttttctgttt
     5221 gtcgctgtct caaatggaca tcatagagta gctgttcatc gtctaaacgt ttgatgaaag
     5281 tttcagaatt ccataattga tccattgttt cccgttgatc tcttaaggta tgatcgatat
     5341 atacgatgtc tctttcaaga tctgcctgtt tatacagttc ttcattttcc gttgttttac
     5401 gagctgcttt atccaaagcg tcaattcgct ttttcatctc tcttagttct ttcacgtaat
     5461 gggtgtaaat atctaataat gtatacgtga tgatcttttc aaacgagttt aaatgatttc
     5521 catgctttgt cagcagccga tccacaaatt cggtttttct atcgatacaa gtaatcaaga
     5581 gattatcgga aagtacaaaa gatattggcg ttaatttttt ttcgatacga ttatctgact
     5641 gatctagatt aatcactacc aaagaaaatg gatgctctag tttcgtctca taaaggcgct
     5701 ccatccgaga aacttcttcc ggatattcgg ttcctacgaa aatatcatca ggaagctcga
     5761 attcttcgat tgcttgctca atctcttcgg gctttgcact atcaagtacg agccaattat
     5821 attttttttc atctgtttct attacattct tttcttcatc cacaaagtag tatctcaatg
     5881 tatacctcct ttttggactt tctcgaaact attagctgaa gaagcagttc tttaatttga
     5941 tattataatc gagtactgcg atttcatttt ctaatgaaaa gctgtcaagc tgtttgttga
     6001 agtccatgtt caatcgttta ccgaaataat tttgctctaa tttagatgta tagatgtcca
     6061 ataatggatg ctcgatttta gtcgcatatt ctccaaattc cgaaacaaaa ggaatgattt
     6121 gaaaaaagct gccttttgca aaagcacctt tgtcccttag aaatggatcg gaatcattga
     6181 taagcgcgag tgcgattttt gtattttccc caaccttttc aattaacgtc tctactgcat
     6241 ttttagacat tgtaatttcc attcctactc cccctcttca gttgttgtct tctattattt
     6301 aacaactaca tctgtttttg gttgaacttt tgcatatttt ggatatttag ggaatttagc
     6361 tacacaacgg aaagccgtca tccctgcata tttttcgtaa tatttcttcg ttggcccttc
     6421 aaaatccttg ctccacggtt tcacatgtcc tgaaaaatgg ataatgtaag gattgttgcg
     6481 agtttcttcg tattcacgtt cacctgctgc tgttggatgt ttttttgctt ttgccatgat
     6541 atagccttgt gcattccaac gcggatgaag tggtaaccaa cggtcatgta agatagcatt
     6601 taatgcatct tggtcatgga atcgtaattt ttctggatta tgttcgatga aatctaatac
     6661 tttttgcgta atattttcat ctaaccattt tttcacattg atcagcatca aacctgagtt
     6721 gaaataacgc attgatttag ctgaaatttt cattttttcc agtcgttgat ggaacccagc
     6781 gtcttcaaca gctgctacga ttgaatcacc gaagtcaaga cgccataatt tagagatatc
     6841 ttgtaaagcg atcatgtcgc aatccatata taagatacgt tcaacttctg tgccgcggaa
     6901 caattccgga atcgcaatac gataataagc tgtttctgga atacgatcgc tgattaccac
     6961 atttgtaaag aattctttat tgattttcaa gaattccaca tctgagttca ttcgtgcgtt
     7021 tttcactgag aagcgtaaaa gctgtttact ttcaaaatcg atatcatcgt caatcacata
     7081 gaaccgaaca aatttagacg ggttgcaatt atctaatact gagacaaata atgcagctaa
     7141 atgtggtacg aattttgtgt tacaacttgc gactactgct atttcttttt tattcattga
     7201 tctcgcctac tttcgttaga gtactgtgtg ctaatttttt taagtataaa ttggtatacg
     7261 gatgatcttt caacgtattc caaggtttat catgtcctgt aaagtgaacg atcgaaggtt
     7321 tttcatttcc ttctttatac tgacgttcat atttttcatt tggtgctgga tgacgttcaa
     7381 aaatcagcga agtctgcatg ttccattttg gatgaagttg ttcccaatct tcataaagta
     7441 cagcattcaa agcatcttgg tcgtgataga tgattcgatc gccattttca ctgaggtaat
     7501 ggatagtttt ttctgtaatt tcttttttat tccattgatc aatgtcaatc accatcactc
     7561 ctgaattgaa gtacaagtca tcggaatcga ttcctaatct ttccaaagct ttcacttggc
     7621 ctggatcgat aatagcgccg attgtttttc catttaacgg ctcatcatat agttttacga
     7681 tatcgtctag tactaacaca tctgaatcta agtaaaggac tttcttataa tcctctttag
     7741 ctaataagtt tggtaaagaa attcttaagt aagcggtagt tgtgatatgg tcactgacta
     7801 ggaagtcttc gtagatatct ttttccactg tcaggaattg gatacttgca ttacttgaat
     7861 atttatttac cgtttcttcc aatccttctt tactatattc tgatagacca tcgtcaatca
     7921 cataaaattt tatgcgtctt gttttattgc aattttctaa tgcagttgcg atcatcacgc
     7981 tcaagtaagg agcataattt tcgtctgaag cagttaccac aggaactacg ccgtatctct
     8041 tctccatcaa aatcactcct ttttctaatc tttttctaac ctgttctaca tctagaatat
     8101 tcctcatttg gttttaaagc aaaatatatg ctttgttttc attgaatatt ttaaaatttt
     8161 tttatcacaa aacgcatcgg taagcgctaa ctattcgttt ttcatggctt tttattcaaa
     8221 ggtattgacc aaaaactact atatatagcc acctttttct taagaatgtt ttttgaaaaa
     8281 attcataatg acaaagcaag ttagtttcat ttttttaaat tctcatttaa tcttaaggta
     8341 acaggaaaat agatatgtaa aaagaaagta ggaagataaa atgaaactag cagcgattga
     8401 tttagacggt accttgcttg atcgaaatgg aaagatacca gaagaaaata tccaagcact
     8461 tcggaaattt gatgaaaatg gcggaatcgt aaccgtcgct accggaagga acagcatttc
     8521 tgctaaagat attttttccg aattaggaat cggtggctat ttgatttctt ccaatggttc
     8581 actgattgct gaaatgaagg atggaaaaat ggcgaaagtt ctcagacgtt caaaaataga
     8641 tagcgataca ctgagaaaag ccttcttcta tgctcaagaa gcgaaaatat ccatcattgc
     8701 tagccgagaa acccaagatg atcagctgac attcgatgaa tcaaatctag tcaaagatga
     8761 cccttattat gaacatttca atttacagaa ccattctttt gatcaaattt taaatatgtt
     8821 ggaagatcct tctcttagct atcttaaatt agcattaaca gataagagtg aagaaaaact
     8881 acagaagcta caaagagatc tgcaagcaga tggtatccaa tcagtattct ctgatccgca
     8941 tttcttagaa atcacgccta caggtatcac taaagctcat tcacttgttt ttctggcgga
     9001 ttaccttgga atcgaatcga gtgacatcat ggcttttggc gatcaagaaa acgacattgc
     9061 tatgttgaat tacagcgggt tgagtattgc gatggggaat gcacagcgac aagtaaaaga
     9121 aattgcaaac caagtaacac tgacgaatga agaagctggt gttgcttata ttttaaaaaa
     9181 cttctattaa aaagaataaa atgacgatat gaatgtagga ggaaagaaaa tgttagttat
     9241 tattgatatg caaaatcata ttcttgatcc aaacagcgaa ttttatattc cagagtcaga
     9301 tcaattggca gaacgtattg ctcaaagatt agctaaagca cgccaaaata atgaatatat
     9361 tctcttcaca cgggatatac cagttgaact gaaggacaaa gaagaagaac gagaagattt
     9421 gcaattgatc cctcttcttt ctccacaaga aaatgaacga gtgattaaaa agtattactt
     9481 tacgattcca cctgaaactt tagctgaaat ccaggaaact ttatttgaaa gcaaagaaga
     9541 acaaaaagag atcgaagtag tcgggattga aacaaacttg tgtgtactct ctaatctgat
     9601 aggcctgcag agtgcttttc ctgaagcaga cttttttgtt gatccaatgt tagtctccag
     9661 tagaaaacac ggagaatccg ctttagagct gttgaaagat ttcaacgtct ctatcgtcga
     9721 atcataaaaa tatctatctt catttacgat atttaacaca caataaaaaa agcacgcaga
     9781 actgttttag tcctacgtgc tttttctatc aaagtagatt ggctttttta tgacacagag
     9841 tgaaacggca ggctcacgac ctctttctta aatggtgttc aatcagctga ccctcggtat
     9901 tagcttaaca aacggcaaaa tatgaggaac tatttttccg tttgttaagc taatactcag
     9961 gtcaaaacgc tgatttcaca acctcttcct taaacggtat tcaaaagctt gcatctgcag
    10021 taataagaac agccaagtaa aaacataaga agctgttttt acttggctgt tcttattact
    10081 tgatgcaggg cagctttttc acaacctctt atgtaccttg taggactcga acctacgacc
    10141 ggacggttat gagccgtctg ctctaaccaa ctgagctaaa ggtacatcat aaataaaatt
    10201 tatttttgtt acttttcaac tatagcacga atgacaaact ctcacaagtt tcaaaatata
    10261 agtaaaataa tattgttatt cttatttctt ttacttgtgt cataactatt ttgttacttt
    10321 aatttttatt tgcttatttt agaaaaaatg ttattctttt atttattctc aatgttagga
    10381 gtgattattt tgccatttat tgcgatttta ttcgatttag ttgcggcagc agcttatttt
    10441 ctccaattaa attatcaaac ctcaggaatt ctgtttattg gaatgatttt tcaaggtgtg
    10501 attacccttt tgcttcttgt catgatgctc agctataaag gaaaaagata tgcccgtatt
    10561 caaacaaaag tatttgttaa atatgtttcc attcgctatg ggatcatcat tctttccttt
    10621 ttagtgaatg cgatcgtcct ctttttatat gtattgaatt acttagatat caatccattg
    10681 attttttctc gatagataag acacattcag cggaacagtt cctgcttatc agcagaaaac
    10741 tgttctgctt tttcattttt cattgatcta ttcttctttt attttcctag catttcattt
    10801 gtgatgtatg caataacatg ttatctttta ttatatgaat cgttgaggag tccgttacat
    10861 gattacgttg gtgagagttt tgttttgggt gcctgcggtc gcactggtcg caagtattgt
    10921 ttatcttatg aattggaaca aagaacggtt ttatttagct attttgactc ttccggctat
    10981 ctactttatg tggaaagttt ttaattacaa ctactttgaa cccgatagtg tttttataga
    11041 agaattatca ggactggttt tgtctttatt gatcgtcatt ctttatttga tacgtttaaa
    11101 taaaaaacat tgagtactat tgattgcatg tgtagctttc tatagtcatt ataactattc
    11161 tactataatg aaaggtgatt aaatgagtat cgaagaagct attttactgg atactttacg
    11221 ttgtcgtctg aatttcttaa gaactggccg atctttatct caagtagctg tttctagcgc
    11281 gttaagtatt cctttattca aatatcgtaa gtacgaagaa ggagaagaaa ttccaagcat
    11341 cattgaatta atctatatcg ctgactttta cgatatttcc gttgattacc taattggtcg
    11401 ctcagaaaca gcaagcaaac tgaagtgatt ttttccagcc ttggtgctgg ttttttcatt
    11461 taacgtctaa ggttaacaat ctatatataa aggagacatt tctatgcgat tatggcatga
    11521 aaaattgatt tcaaagcttc ctcgtcaaca gcttttagga caacatcggg aatgctgtgc
    11581 attaagagga aatggctggg gaaagaaaca tgctactgtg gattatgttt ttcactattc
    11641 tccttataga ttattccaat atcatcagct tgtcatggat gaaatggaaa aacgtggtta
    11701 cagcccagca ccagagtgga aaaatcctat gtatcgtggc aaatcatgcg aagcattttt
    11761 tgatttacct actgtagagc gcaacgtgcc gatttatccg gaacacgatg aagtttatct
    11821 agcagaatgt ttagcaaatt tggagcaaaa aggaatttat cttacctaat ataactagaa
    11881 aagccttcta tctcctctta cttcattaaa aagctttaac catcttagat caagctaaaa
    11941 tgtcgtaagt tttagggtta tcttcatcct cacgtgcaaa actaaaagcg tactctagtt
    12001 ttggttcatc gccaacttcc ctagacataa atgaacatct cctgacgtgg tttaaaagta
    12061 ccgcatcttc gacgtctgta tacgatgcac agcacagatt gcttcttttg atctttcttt
    12121 tgatttttct gttgcttctt ctacaccttc ttcgattact acatcgatgc ttacaattgc
    12181 ttctgcctaa tattcccatg catcgtcgat ttaagcctct gtagtcactg tgatcgtttc
    12241 cacattttaa ctcctctgtc gtggcttcag ttgattttgt gatcagttca gttgctaagc
    12301 cagagtcaga acaacctgcc attgctagcg ttaatattga tagtaaaaat agttttttta
    12361 tcataaggtt ccccccctga aaatagacta aaataataac gctttctttt tttgttttca
    12421 gacgaaaatt aataatttct aaatattctt taaaaaagct tataactatt atgccttttt
    12481 taatatataa cacagttatt tttaaaaata agaatgctaa atcactctac aataacggcg
    12541 aaagcacaaa aaataaaaaa attattacgt tattaaaaaa acagatgaaa gatcaggttt
    12601 tattagatct cattctttca tcacttgaag ggatttaatg aactactttt tcctctttgt
    12661 cgtttttata tattcgtatt ccttcaaaca gtaggatagc ctctttcaat gcttgatatt
    12721 tgaactgtcc gttacttaaa aatttagatg tgccgccctc ttcctagaac atattctttt
    12781 ttactttttc attaattgac agaccaatcg aacgaaactg taaatttcga taggataatg
    12841 attggtcaaa ctcattcatt ttcaagacat ctcgattcat attcaagata ggaatctttt
    12901 tatcaacatc actttattcg tattttcctc taccataaaa gcttcacgct ccacaaaatt
    12961 gttttataca ctactattca gcccattcaa cgaccaatga attttttcgg ctctataatt
    13021 tatgggactg atgaatcaga attgattctt cagccccata aattatagag ccgataacag
    13081 tagatgcgtt ttgtgtttgt tctaaattgt tcactacaaa taaggtagat acttcaaaat
    13141 aaaaaattac ttctttttca tctgttccct cagtcgtgca ggacaataaa taaagaggac
    13201 tagaaaatag tcctctttat tagagataca accctttact ttctaaaaat cgttttgctt
    13261 gatgcaggtc ataaaattca tagtctgctt tattggattc atataaactt acatctactt
    13321 tcaacttatg cttcccatta tgatcgggca accctatcaa atgatctttg atgagaaaag
    13381 acaaaatgcc cgctcgcctt gctgcttcga tccctgcaat cgagtcttca aatacaagtg
    13441 cttcacttgg aggaatattc atttttgaac aagctttcaa aaagatctct ggttccggct
    13501 ttcctttttt tacatcatcc cctgaaatga tttgatcaaa caaggcatat agattttcca
    13561 tttttaaata catttctact tttacccgtg tattagacga agccacgatt gtatggattc
    13621 ctctttcttt tgcaaaagat aaaatttctt ctgctccttt tttcgtatat actctcttat
    13681 cttctttcac gattttttct ttatattgat tgattgcttc tcgccatttg atatatggaa
    13741 catcttctcc gtacaaaatg cccatttgtt ctcttatcgc catttctgtt tggccagtta
    13801 gtaaataata gacttcctta cgcatttcat aatcatactt ttgtgctgat tttacataag
    13861 cacgataagc taaacgtcca gtttctaata aaaggccatc catatcaaag atgaagagct
    13921 tgattttatt cataatgctc tcccagtggt ttttccttac ttatcgcctc atatagacct
    13981 tgcatgtaag tgagtcccat tgcacgatca tacaggccat atccaggcat agccacttca
    14041 ccccacacgg ttctaccatg atcagggcgt ataggaccgt cgaacccttc ttgcaccaac
    14101 gctttcataa tatgatacat atcaagggag ccttctgtag agggatgtgc cgtttctttg
    14161 aactttcttt ctcctaaaaa ctccacgttt ctgaagtgga caaaatggat gcgcgaacct
    14221 acctcatgga tgatttcaac taaatcgttt tccggatttg cccctaaaga tcctgtgcac
    14281 agcgttagtc cattatatgg agaatctact gcatttagaa ttttcttcaa gtcgccaaga
    14341 tttttcgtca ctctaggaaa accaaaaagt tcccatggcg gatcatctgg atggatagcc
    14401 atttttacat ctgctttttc gcacactgga atcacttttt ctaaaaaata agtcagattt
    14461 tcaaataatt cttcttcggt cattccttca tacagttttt ccagctgagc gaattttttc
    14521 aaccgttctt cttcccaacc cggcaatttg aatccctttg actggctgtg tatcaattga
    14581 tacatttctc ctggctccat ctgatcgacg attttctgat cgtataaaag agaatagctt
    14641 ccatcgttgt tttcattaaa caaatcagtt ttcgcccatc caaaaattgg tttgaagcta
    14701 taacaaatca atcgaacccc acatcgagac aagtttttga ttgttcgtat atagttatca
    14761 atatagtaat ctcgttcatc tgtccctgcc ttgattgcat cgtggatcgc tacactttca
    14821 attccaagca gttccagtcc ttggctctca acagatgctt tcaactcctc aatttctgaa
    14881 atctcccaaa catctccagg cattttagtc agcaaagttc caattatccc atttattccc
    14941 ggtatttggc gaacatattt taatgggatc gaatcccctt tttcaccata ccatctaaat
    15001 ccccacttca tcttttcagc cttccttcta aaaatcgtcc tcatctaatt ttttttcttc
    15061 cgctgaagca tgccaaacag ttaaattatc ttttccttgt ttgacaattt gttccaccgc
    15121 ttcttctatc ggtgtgtgaa gcatctgatg attgattgct tctaacaaca ttggcagatt
    15181 cacgccccct atgacataag tggctgcttt cttttcttca gtcagttcat tgactgccaa
    15241 gagcgcttga ttgtacggac ttgcgctaat tagatcaaca aatactagca tgggttctgc
    15301 tgtgttgatc atagttaatt tttctttgac cttctctccg aatgtttgga tgtcctcccc
    15361 agactctaag cacattgttt caatatggct cgatgtcccg acaattactt ccgccgcatc
    15421 tttcagtcct tcgctcaact taccatgtgt aacgatcatg atttccaaca ttagtcttct
    15481 cactccttgt tttgcacttt ttacttatcg aaaaagagca ataatctgat tggcattttg
    15541 ccaattaaat gttttccctc gtaaatctgt tttggtcaaa tagaagaact gcgcttgctt
    15601 ttttcttgca ctaaaaatat aattgacgtt tttttctttc aacttatcaa cttgtttcag
    15661 ccactgttct ttatttgaaa aataatttcc cgaaaactgt agcggtgtat ctgccccaac
    15721 agagtctaga taaaaaagaa tagcctcttt tttcataccc gatctcacgc tgtctaagcc
    15781 cttttctcca taacagcctt catcaacaaa cgcatacgct acactcggat catcaatcgt
    15841 acggatcatt tctagcatcg ttaatatgga tgaagtattt cgaataaaag tttgtctgct
    15901 aggccatccg cgagctgctt ttcccaataa gaaaaagtag ctcccaaatg ctagtacagt
    15961 gatacctgtt tatacggata gcagatcgaa tacgtgatga ggatttttgt tatatatcat
    16021 cattccccac caacctaaac tgaacaacaa aatgaaggac aataatatag agtagattgt
    16081 ttttttcctt tggtctttcc aatcaaacat gaaataactt cctaatgcat gaacgggtgt
    16141 atcgtaataa gtacagataa ctttctctgc tttttcgata tctccaacat aaatattttt
    16201 tgatcggtag gctagcgtat cgtaagcaat gactgtcaca tctgttctca tactgtaaat
    16261 atctgatact aatgctgaaa gaaaacgctg tttactcttt tttgtacggc gcttacggta
    16321 aatatagcga taacgaaatt cccaatcacg aaacagctcg ttcttcttca ttttttcgcc
    16381 ctctttatct tttttctaag catttgttta tgacaaatca aacttgttca atacatcttt
    16441 taatcctgtt ttaggtgcag atggagtggc ttgaaaataa atattcttta cgccatattg
    16501 ttcattcatt tctttcaatt tttcagcatc tgatttattt aaataaacag atttcgtcac
    16561 taaaagatct gtatcaggat ttttttgagc aatccctcca atattcaatt cttccatggg
    16621 gattccgtgt tttactaagt cgtaaatcgt ttggactgtt tttgcgatca aaatacaatt
    16681 gtattcttta aattgatatt catcccaata gaatttagct ttctctggtg taatgacaat
    16741 tgttttttgt cctgtacggc ttcctgcatt tttgtaaaga tctctcataa atttatcttt
    16801 tgctacaact tcgtctacaa caaaaatgga attcactcca cttttttgag ataacgttac
    16861 cattacttgc ccatggatca aacgctcatc cacacgcgct aaattgacta cacccatctt
    16921 attcacgttc ccttcttttt ataaaatacc gattcctgct agcacaatta atattccagt
    16981 cagccataat aatgcttgtg tgactttcaa tccttttttc gtatagaaca agtacacacc
    17041 cattacgaca gctaaaggta atatccctgg cacgatttga tcaagaattt cctggataac
    17101 aaactcacgt ccggatatcg caaatttcaa tgaagattct acttttacat agtttcccgc
    17161 aagcaccccc atcataaaca accctaaaac tgatagcatt tcaatcgctg tctgaacacc
    17221 agtgttttgc tttaggcctg tagcattacg gcccatagtg aaagcttgtc ttgcgaaaaa
    17281 tacccctagt aaaacctgat acaacccaaa gcagataaaa ggaaaaagtg cgcctaaagg
    17341 acttccctgt tgtgcccaag gtaccgcgat tgcgataaaa atatattgga cggttcctga
    17401 atcgattgca tctccgattc ctgctagtgc ccccatcaat cccgctttcg tgttatacat
    17461 caagtcatcc tgcatcaaga tctctttttc ttcatactct tcttctgctc tttgctgttc
    17521 catagaagac attaggccag taatcacacc gccaccccag cttaattgag tgttgaagaa
    17581 cagtaactgc cgtttatatg ctgcttttaa agagtcttca tctttataaa gttttttcaa
    17641 gattggcatc attccgtata gtagtgatgg cgccaagtaa cgttcaaaag agtgaggaat
    17701 ttcgtttgca aaatgccatc tcagataggc ttttgttaca tcttttttcg tgatttcttc
    17761 aggagcacct gtttgattat ccattatttc agccatttcc cattcctcct aaattaaaat
    17821 ccgtcatcat agtcatcttc gtcatcaaaa gatgctgaat tgttattgct tgtggcaggc
    17881 tgtacttgtt tccctttttg cgactggaca aagatcaaag cgataataat cccaaaaatg
    17941 gcataagtaa ccatcgtaat atctaaagat ttcaaaacaa cactcataaa ataagcaagg
    18001 aagaaaaaga ccagataatc ttttcgaccg ataacgtata cagttgtcgc gataccgatt
    18061 gccgctaacc ctccacctac tacttcaaga atgtggataa cgactgttcc ctctaaagct
    18121 ttgattacat cagcgatcaa tggcgcccct aaatataaag caatgaaaac aagcggaacg
    18181 aataataaaa atgaggcaac cgttggataa agaataattg atcgggccat agcttttgta
    18241 ttcaaatctt ctacagcttt gtctgtatat ttacctaaaa aagtattgat gaaaaaacga
    18301 aactgataca agtaacttcc gagcaatccg actggcaccg caacggcaat cgctgcttct
    18361 ggcgacagat cccctaataa tgcgactggt actgcgatag ctgctgcaat agatggttca
    18421 gctggcattg atcctcctgg agaaaaaacc cccatataaa tcatttgcaa agcggctgta
    18481 acaatcatcg cttgtgcaac ttcccccatg atcaacccga cgactaatcc agtcatcaaa
    18541 ggagaaaaac gtaaggtcaa cgtggctcct ccacctaacc agcgggacat aaccgcggct
    18601 acccataaag caatcaacaa actttgtact acacttaatg tttccatgtg tcctcctcct
    18661 tcagatcttt ctgatataac cttccagttc catcattgac tgtatcagtg atttctgtgt
    18721 tacctctata ggaatcaaat gcactttctc tttcgaatca ataaattcag ccattttatc
    18781 tattatctgt ttatctttcg gaaataatcc catttgttct agagaaaccg gcagttctaa
    18841 ttcccgatac aaaggatata actcgtctat tttttcccag cgaccttcta gtgccagttg
    18901 atagaaaatc ccatacgcta ctttttctcc atgtagaaaa cgatggcttt ccggaatata
    18961 tttactgata gcgtcatgca tagcatgtgc tgccacattt cttgcgtatt tatctcctaa
    19021 tcctccaact aaaccagcaa cagcaaagat aatctctgaa agctgtttga actccgatga
    19081 cagttttctt tgtgccatat cttggattgc tttagcagaa tgattcaaaa tctcttcttt
    19141 gcagatcttc gcagtatctt gtgctagctt caaaaatgat tcatcttgca aaaaatcttg
    19201 ttctaagatg agctcagatt cataccattt tgctagtgta tctgctaacc cggcaatgaa
    19261 atatggaaca ggggaatcaa tcactaattg gggatctgtt ataaaaaaag cagcttgtct
    19321 gtaaaagtgt tctgttttcc cttctgcttg tccattctcc ttatacatga cagcaagagg
    19381 tgtccatgga gcacaattac tagctaaagt agggatgact ccgaaatcga ttcttgcaag
    19441 attggcacta taacccacta gatcggtcag ttttcctccg ccaacgccaa ctacgaaatc
    19501 gatttcattt ttttgatgat tgtagctatt cgtctggctt cagcataact acattctcca
    19561 gaataacgat gataaaaaaa ttgaatcgtt tcgtcattca aaaatactaa tttaggtagc
    19621 gccttttccc atgataccgt tccgtgggtg accagtactc ttttcgcgcc gtatgatttc
    19681 aagagatcag aaacttttga aataccacct tcttcatata aataaaattg agggcctgtt
    19741 ttcactttta aaccgttcac cattttcttc atcatccttt tatatagttg ctctttgtct
    19801 ggacagaacg ttcaggaaga aggtgctgac tgatctgttc gacatctctg acacattttt
    19861 cacacattgc ttctaaacat tcccttgtgt aggccgatat atgtggcgta atcactactt
    19921 gttcaaacgc taaatacgga tgatcttgac gtcccggttc ttcttctaaa acatctgtgg
    19981 catatcctgc gatctttccg cttttcagac cattaatcat cgcttcttca tcaactagag
    20041 cgcctcttgc actattagat agataaacat tttctttcat ctgatcgact tctttatcag
    20101 aaatcatgtg atagttctct tctgtcaaat tcgcacataa acaaatgata tctgattgtt
    20161 ccagtaattc ttgaagttct actttttttg caccaaagct ttcgatgtat aaatctgatt
    20221 tgtaaggatc ataagctaga acatcacagc gaaaaccgtt acgcaaaatt tcgattactc
    20281 cgcttccggt atttcctgca ccaatcacac caactgtttt gttaaacagc gtcctaccga
    20341 cgaactccgc ccgatcttcc catcgatcgt ccttgactct tgcttgtgct tgtgtcgtgc
    20401 gtcgaagcat ggacaacaaa ttagttatat tattttctgc tacagcattt cgttcaacta
    20461 aagcaggtat gatagatacg attgtctggt gttcttttgc tgcttttaaa tcaatattgt
    20521 tgtaaccaat accatgtcgg gaaatcaata gcagttcatc tttgttttca aaaaaatctc
    20581 gtcgaaaaaa tggcgtaaca cttgcaataa tgatattgaa tcctttaagt aactccgcta
    20641 gttcttttcc tggaatctct tgatcaacat taaagaaatg aacgtctcca actgacttta
    20701 atctttccaa gtggtgtgga aagactcttc cgaaactgct ggaattaacg attgctatat
    20761 gataatctgg cattttactc acccttttca actatttcat gtccgccaaa cccatttctt
    20821 agtgctgaaa ctacttttgc tgaaaaacta tcttcttcct gtgaaagatt cctcatgaac
    20881 aaactagttg caattactgg aactggaaca gccatttcta gcgctgtttc aaccgtccat
    20941 tttgcttcac ctgatgcaga aacgattccc cgataattac ttaaattggg atgttcgttt
    21001 aactgatctt ccatgatttc catcagccag ccgcgaatca ccgaaccatg attccaaaca
    21061 cgtgcgactt gttccaagtc aaaagcatac tcactttttt gtacaagttg gaatccttca
    21121 ccgattgctt gcatcattcc atattcgatt ccattatgga tcattttcaa gaagtgtccg
    21181 cttccggatg caccagcata cagatatcct ctttcaattg ctacatcttt gaataattgt
    21241 tccacggata gaaaagtttc tttatctcct ccaatcatta agcaggcttg atgtcgtgct
    21301 ccttcgattc ctccagaagt cccacaatcc aagtaaccga tttcattttt ctgaaactct
    21361 tctgctcgac ggattgaatc tttataataa gagtttccgc cttcaataat aatgtctcct
    21421 ggtccgagtt ttggaaaaag ttttcttaac atgttttcgg ttatctctcc agcaggaagc
    21481 attaaccaga tgattttttt ctgctcaaaa gtagctagaa attcagagat ctcttgataa
    21541 gcaggaatgt cattttctct tgcctgacta acagctgtac ttgaaatgtc gagtccttgt
    21601 actttgtgat ggtgctcttt taagtttaaa gctaaattca atcccatttt tcccaaacca
    21661 attacaccaa tttccatgat agcgcctcca tttcttatac cctcattata caaaaaaatt
    21721 tttttgtaaa tagattttac aaaaatattt tttgtttgat tttttcctac tctccttgta
    21781 tctttaacat taatgagaac ggaaaaaatg ataatcttat tatgaaaatg aggaattctc
    21841 atgagcgtct ccataagact acaaatcaaa acaatgtaca acgacttcag cccaaaagaa
    21901 caggctatcg ccgattatat tttagaaaat ccaagcaaag taagtcatag tcctattagc
    21961 aatttagcaa gtgaactggg cattgctgac tctacttttt ttcaatttac aaaaaaactt
    22021 ggttataatg gatttaaaga ttttaaaatg gccatgttga tccaagaaaa tgatctatct
    22081 gctatttcta tccacgaaaa tattcagaaa acagatactg agctcactat ggcgcaaaag
    22141 gtgttcgagt ctagtatttc aactttaaat gacacaaaaa agttgttaca acaaaaggat
    22201 ctaaaaaaag cggctactat tatcaatgaa tctaaacgtg tctatttttt cggtgttggc
    22261 ggttcagaga ttgtagcaac tgacgcttat cataaatttt tgcgttcccc tatcgcaact
    22321 tctcacagca cggattacca tattcaattg atggaagctt ctttattgac ggaaaaagac
    22381 tgtgctgttt tgatttctca cacagggcaa tcaaaagaaa caatccatat tgctgaaacc
    22441 gtaagaaaaa ctggagcaaa aacaatcgtt attactagcc aagctaattc ttcccttgct
    22501 aaacttggcg atgtcgtttt tatttctatt tctgaagaaa cagaattccg atctgaagct
    22561 ttagcttccc gtatttctca actaagcatt ttggactctc tatatgtgat tttgatgttt
    22621 tacaacgaaa aagaatcacg tcgttctatc gctaaagttc gacatactat ttctgaaatc
    22681 aaagaatagc accataacag aaaaagcgaa aaatccataa aacaaaaaaa gccactacca
    22741 aatatttggt agtggctttt ttggttctgc aagggtggta cagaacatca atagtcggtg
    22801 ggttagaacg tatgtcatcg catctttgga gaaggttgta ttggtattat tcgagttact
    22861 tgttagatgc gataacaaag ttagtataca gtagtaaaaa atttatcttt tctttttttt
    22921 attatttttg tttcttattt tctaaaaaat taaaaaaaat tttggtgaat taagtatttc
    22981 cttgataaca ctggcttttg gcctcatttt aggttatcat ttgtaatttt atttcacagt
    23041 tgatatgatt gttatgtaaa ataaaaaagt ttaggataca tcgaattttt ggggaaattc
    23101 ttttgggggt atcctaaatc ttttctatta tattcccata ttttctatta ttggtctaga
    23161 cgtatgatgg taaactttgt acctatctga ttgctgaatc attaattgct tatcattagc
    23221 catctttgtt tcaagttcgc tagatgatca ttttattcac atcctaacaa acttgtcaca
    23281 tttatagatt cttaatctat ttatcataca attataaaaa aggaggtgct gcttatgaaa
    23341 gctatccata tttctttgct ttttttcgct agtgcattga ttttatttgc tattcatctt
    23401 tgttcccagc cttatatcaa taacaacgga atattagtgg aaccagcatt cttttgctta
    23461 ccactcggct ttttgtccct tcttgcctcc gcaggcttcg gatttgttgc tttttttaaa
    23521 cgatcaaaac aacaaatctg acttataaaa tttacgtaaa agagatcgtg acaataatcg
    23581 tgtgatattc ccaaatttcg aataaaaggt gccccttgcc atctctaact cctcagtcac
    23641 aagttacaat attcataaac catgaaaagc ttgtttattg aaattgctcc ttgtgacttg
    23701 gagctaagtg acagattaca acctcttttg catcataaga ctttactcct tgaaaaacat
    23761 tactaacttt tgatatgttt cttgcgcttg tttattgctg aaatcaaact gatattcatg
    23821 gttcaaaaca gcatttttct ccgcataatc tacttttgtg actttcaccc ccgctttctc
    23881 aaatacagaa gttacttctt ccatttgttt cgtaaacgta tttgtatttc catccgttaa
    23941 gaatgtgttt tgcgtccaac gatccgcatg tctgaccaag gctaaacttt tgaccttctc
    24001 tgattgttca aagtccttat tatcaaagta agcccatcca catttttcat aaagaaagct
    24061 agagatttta tcacttactt gagtaagtgc agaaggatcc aacagaccag acaaagaaat
    24121 aaacttcgta atctgcttgt tctccaaagt cggatcaaga tgatcagctt ttttaatttc
    24181 ttcattttga agtgctaaca aatattctcc actaatttgt gcacctgccg aatttccacc
    24241 aatcgaaata ttcgaccaat ctgcttgatc ttttatctct tttttagctg cttgaatggc
    24301 ttcgttcaat tggataactg gtgtaggatg ttttgcttcc ggtgatcgtt cataatctat
    24361 atttacgatg atttgctgcg tgtctgaaca tagatattcc aaataatcac gacaatcatt
    24421 tttatcccct cctacatatg cgcctccatg catccagaaa agaatcggta attttttctt
    24481 ttccactttc ggtgtgtaga tatccatatt attatttttg tactttgaag gataggatat
    24541 ttcttttttt atatcgattt gttcgatttt ttgctggaaa tcatctggtc gggcatatac
    24601 ttgttctttt tcacttgtgt caaattgttt tctaacaagc aagctaatcg gctttggtgt
    24661 gatttgatta atcaaaaata cagtgactaa aataactacg atgataactg gtactgcaat
    24721 cactattcgc ttgaaccatt tcattcattt accctctctt tcttcgccaa atccatgtga
    24781 taatcgtgct aacagataaa aatccacctg aataaatgag aagcgaatgt ttcttttctc
    24841 cagttttcgg caacattctt ttttttgcat ctgtcttttt ttgtactttc actgtcatct
    24901 gaatcggttg cgtatcatca cttgattgat cctctcgagg ttcattcttt cccttattgt
    24961 ctgcattctc tgtcggatct tgcttttttg gtggagctac tgggattttt ttgtaataga
    25021 aaataatagt tggtatcgtc tcattaaaaa tcccttcagt cggtccttca acatttgcta
    25081 attcgtatcc ttcgaatgtc ttttgctctg tcatataatt ttctccataa gctccgtaaa
    25141 gctggatttc gtcctggtct ttgagtagac ttttattgtt ttcatccaca tactttacgt
    25201 ttatctgatc atggaacact actttcaaaa agtccgttac atgtttcgtg taggcagcat
    25261 ggtcaacttc ctgtgccttt ccatgccctg ctccttctac taataaaaga tctttatacc
    25321 ctcctgataa ctcatataat ttttgcgcgt tagacacagg tactacatca tctgctgttc
    25381 catggataat caatttaggc aatgaatctg acattccaat cgtaggtaga gcagcttttg
    25441 tatccaaatg catctcctga tcaaaatagt attgtttcaa aaggcccata aataaatctt
    25501 catgctcttg atccccaatg atgtctaact gattttttat ggcatccggt agtgcggggg
    25561 ctactgtctg gctgtacgta aaacgtagtt gttcatcaat tgatgcaaat ccgcaatttt
    25621 caataattcc tttgacattg acaggaatat ctttcgctaa tacagacatc atcgtagctg
    25681 ctcccatcga accaccataa agtaaaatct tttgagatgg ccgctctcga acttcttgat
    25741 ttatccagta aaggacgtca tctgactcat attgtccata ggtcacataa tcgcctccgc
    25801 tattaccagt cgctctggaa tcaacaaata ataaattata cccggcctta taaaaatcat
    25861 tgtattcttc tgtaacgatc ccgttattcc aattccctcg aaatccgcca tggatcatga
    25921 ctgttttatc tgaaccttga tcgacataat atgcatatac atccatcatt ttgccatctt
    25981 gtttgtttag tacagtttga tgaagttgtt ttgtatttgg atagaagcct gtgttttctg
    26041 taggcgttgt cccatcatct gtacctccaa gcatcgacat caacacactg ttttttgcaa
    26101 aagcgatatc gtacaataga taagtagcaa tcagatgttt gataatctct ttatctacac
    26161 cataatcatt aacagcaagc tcagtgacta ataactctat taattttgac ttgatgtctt
    26221 ctgttggtcc attaagtatt tctgtcatct gtttaccgaa gtaattcaaa tattctttac
    26281 cattgaaatt ttcaccttta ccgatatcat cattttctgt cccattctct ttgtcactta
    26341 ctttagcaga agaggattcg tcgtttgaca tttttgtagc tgttgcttct tctgtttgtt
    26401 ggttatctgt ggtagcggtc gtttcttgat ctgtgctagt aacagatgtc tcaaccgttg
    26461 tttcagtatt tgtttctgtt tgtgaagtac tcgatttcgt ttcatttcca gcatcagtag
    26521 tttctgtggt ttctacctcc cgagattccg attcggaaga aatgctctct ccatatactg
    26581 tccattgcgg gacgcttgta cttacagcaa ataagatgac caacgctccc tttaatactt
    26641 gttttgttct caagctattc actccttttt atgtttctag gagaattata tgtaaacgca
    26701 aacatttttt atacaaaaaa taaatggttt atcccataaa aatagaacag gattattttc
    26761 tcattttacg taataaagca gaatggataa accagtatcc attctgcttt ttttaaacga
    26821 agaaacaact tattgctcca aaaatgtcag aaatcgttta tcccaaattt tctcgtaaaa
    26881 agcgattgtt tcctttgctt tcataaaagg attatcataa gttgtcgttg ctcctctaca
    26941 catcataagc tggtatccta atccatgagc aaacttcaca gtcgtatcta tacaatactc
    27001 tgcttgtgcc ccacataatt cgatcgaatg acagtccaat tcagttaata aaacactcaa
    27061 attagtctta taaaatgaat tcgcatgggt ttttctcaca aaataactgt gctcaggaat
    27121 agataattcc gacaatagct cccatggttt tgtttgtggc actaattgag catcttcgtg
    27181 ttgaacgaaa ataactggtt tcccaatcgt ttcgtatgtt ttgattcttt tattcactaa
    27241 tgctgtcact gtttctaatt cgtgtatcgg cgaagaatca aaacataccc ctttttgtaa
    27301 atcgatcact actattgcgt cggctgtgtt tgacatactt gtgccttctt tcttttttct
    27361 tgatttaata gtatttctta tctagctagt tccattatac gtgacaacat tttcttattt
    27421 tacacctcta aatggcactt ttcgactatt tcttcatgtt attatttcat aaatacttag
    27481 ctattggagg aatgtatgat gattaaattg tatacaggtt ctggctgctc gtcttcaaga
    27541 cgcgcaaaac gttggcttat cgtccatgat ataccgttta tcgaacagaa cttaattcgt
    27601 caaccactaa ccaaaaatga atttatccac ttactaaaat tgacaaacaa cggcgtgacc
    27661 gaaatgctct ctactcattc tattagttat aaaaatcttg ttcacagaat agatgaactc
    27721 agtttgagtg aactatatat tgagattcgt acatcccctt ctttattgaa aaaaccgatt
    27781 atctacgacc aatctgcaaa acttttgact ggatttagcg aagataaaat caggatgttc
    27841 ctttctaaaa ctaaaagaaa gcaagagctc aacgaactct tgctttctgg tcatcttgtc
    27901 gattttaaag aaaataatct ttttgcaatg tcttaatttt ggcataaaca atctgctttt
    27961 cttaattaac gaaatccaat ttttccaata tggatctatt tttctcattc ctgattttta
    28021 tgatttcagc tttcagacgc gcccaatcat tttttgtagg ttgtccattc cagtaaaata
    28081 tctgtgtatt cgtttgatca tatgcctttt tgtcgatagg ataatcgcta atgacaatat
    28141 caggtaactg atcagcggat gcactatatt ttattgggcg ttcagtcata gataatatcc
    28201 ttttctttgc ccataattcc tgtgttttac catactttga ttgaatatag aatatgacag
    28261 gttgttcgtg ttttataaaa atatccctga ctaacataca gtattgaaaa atcaaccgtc
    28321 tgttcttttc ataataagta ttaagctctg gaattctgcg agctacccca ctaaaaaact
    28381 gttgcatgat tggatacatc actggaaata tatgctgaaa atctctgtct tctgctgatt
    28441 ttccaaaagc atccaccttc ttttttgtcc caaaaaccct tgaatacaaa tggatcattg
    28501 ccaaattgac atatagataa tttttttctg aagttgtaaa acaaatcttg aagttttttt
    28561 caaaattttc tacaatagac gattcaatcc agccccaact ttcttgtact ttatctggag
    28621 tatccaacaa atcttcttcc aaataggtgt tcattacacc aaacataaaa taaaggtaag
    28681 cttgctctgt tggagtgatg tgattcatcg accagaagtt tgcttcaaaa aaaggctcta
    28741 gtatgtaatg cgtaaactct tcttttgtta tcaatggatg cacaaatttg ttcatctctt
    28801 ctgggacata cgtaatcgag tggccttgtt tcattcgttg caacgaaatt cttagtaggc
    28861 tgatccattt ctttctatct atactacgcg tatatggcgc atgtttcgca aatttttcta
    28921 atagttgacg tttatttttt atacttgata atatatcaga atgattttcg tcgaatgact
    28981 gccaatacat caagtgaaaa aagtatcgga tacggtattc ttctccttct atcggattac
    29041 cttttttcaa gctgcaagat aaatgatagt ttttcaaaat agtattaagt tctcttaatt
    29101 ttctttgaat cgtacgcaaa cttatataat tttttgacta agattttcta aggattgata
    29161 agtacctttg taaagtgaat ccagtaaaat ataaccaatc gttccctcta aaagtataga
    29221 ataaacttta ctcagtaaaa actgagaaga aaactcgact tttatcatct tgttttctga
    29281 aagaaaagat aatttatatt ctggatacct ttcgcaaaac gattctgctt gttgaatcac
    29341 cgaattcatc ttagccaggg tgtagtttag atctaaagcg atatccttca ccacatataa
    29401 tttctcgtct ctttcataac aatagttcaa aaattgatat acttgccttt cattgatatc
    29461 aataaattct tcaaacaaag tacatactcc tttttatcta ttatttagac ttattccgac
    29521 agctacatga ataacgtaca aatagattcg ttactgattt ttcagagata ctaccatgcg
    29581 cagtgtgcat tgtcaattat tcttgctctt attttccatt tgtgttcctg ttatttcctg
    29641 tttctcaaat atgttagtaa acaaaaatag atctggcaaa gctacaactt cgccaggcaa
    29701 tacagcactc tcgaatgaaa tattcactca aaaatctatc gttttattca attttagatc
    29761 tgttgctttt attctttatt tcactcgatg gaagagagaa cgaaaatagc ttgctcctac
    29821 aatcaaaatg agtaacacac ccatccatgt aattagcttg ttcaaggttc tactaccagt
    29881 ttctggtaaa tcgctttttc tattatctgt ttctttcgct ttttcttgat gatcaattcc
    29941 acgagaaaca aaatcaggct gttttagcac actttttagg ttgctccctg catttctctt
    30001 ttgttcctta gttggtatga taggtaccaa atcaagttca ttatttactt ttcctgtgct
    30061 gctttcgctg ctcgtgcttc ctgtgctact ctcactactc atgcttcctg tgctactttc
    30121 actactcgta ctctccgtac tgctttcgct gctcgtgctt cctgtgctac tttcactact
    30181 cgtactctcc gtactgcttt cgctgctcgt gttttctgtg ctactttcac tgctcgtact
    30241 ctctgtactg ctttcaccgc tcgtgttttc tgtactgctt tcactacttg tgctatccgt
    30301 actgcttggc ggtccaacaa ctgtccaact gcttggtttc aaattctccg tgatcgtcat
    30361 ctgtccatca taaaaaacaa tcaaatcaac tttatcttta ctcttgatct catcaatcga
    30421 tagttctgca gaaatcatta ttgtatactc aataccagcg gtccattgta cgtcttttaa
    30481 ataaacttcc ccaataactt tttctgaact tccattacca tcccaaccat atgttagaac
    30541 agcatgtaca tcactagcat tcacgctttt gtttggtttg actggaatag taatgacttg
    30601 ttgtgtcatg tcataaacaa tccgatcagt tttcacagta aatgaaagat tctcatttgc
    30661 ccgttcattt gcagaagtac tgattccaat cattgctgca attatactca gcccaagaat
    30721 aacaaataat acggtcgctg ttttcttcat ttctatcact ctccatataa ttaccttcta
    30781 tttgataaag gaattatata aaatgaaaat gatgagaaca cgacagtcag ttgtgaaaat
    30841 ctaacaaaag atgtcgtgta ttcgcttgaa tttgtttact ttttcgttta atcaatgaca
    30901 gacttaaaaa agcaagaccg atatcagcct tgctttcttc atcttttatt gataaacagc
    30961 agtgtatttc ttcatccgct ttgttttata tgcatagagt aacaaaccaa caatcaagac
    31021 taacaagaat aatgtagttg atatagatgc ttcagcccca aagtttcccc cagtaattat
    31081 tgtattttgc gattggatca gagtggagaa aaaaccttgt tcttgcgttc cgctgactgg
    31141 tatacccaaa atagctcctt gtgtccaatt ccaagtaata tgagcaccaa tagccgtaaa
    31201 taaacttcct gtactgtaga taagtgcgct gaaaaagcaa cctgctaaaa agatattgaa
    31261 aactgccaga aatgtcatgt taggattcaa tccgtgcaaa agagcaaata atgcagcaga
    31321 tccaatcatt gctattaacg gaccaaatct aagcatctga tgctgaaaaa agccacggaa
    31381 taaaagctct tctgatgccc ccactgcaat aaataaaata aaactcgtta tcagcggcac
    31441 aatgtttgcg tttcctgaat ctaaccgata cgcccccgtc aaatataatg gactagtaat
    31501 aagcagaaac actccaattc caacaacgag acctcccgct aaataccccc agtcttttcc
    31561 tcgaacagaa acaccataat cttctattct ttttccttcg accttactag caagaaataa
    31621 agctagtaaa aaaacagcta aatgtccgac cgtaccggca attgctccaa tccattcact
    31681 atttccaata aacatatccg caagtgcatt attgacaaga attcctaaaa caaaaccaac
    31741 taagactatt aaaacagatc caatcaaccg aataatcctg atcatctttc atccctcctt
    31801 tatattaagt ttaacaaccc ttttctttct tgtctcgtga aaactatgta aatgttctcc
    31861 atcatagaga gaatagattt ttacgaacta agaatatcta cagcaacctt acgaaaatga
    31921 aagactgtct ccctaattct tctgttagac tgtttttaat aaggaaagga tgggaaattt
    31981 tttgaaaaaa caactactaa ttatgtgcct ttcagcatgt gcaattttac tattctcagg
    32041 ttgtagcaag tccaatgaaa cgattgcaac gtttaaaggt ggaacactta cagttcagga
    32101 tttttatgat aacccaaaag ttaaatcaaa taatcaaaca ctattaaaaa aaatgattgt
    32161 cttcaaagca tttgatgatg tatacggaaa agagatttct tcaaaggaag taacaaaaga
    32221 atataatgaa caaatcaaaa aactcggtcc aaactacaag gaacaattaa aagcagttgg
    32281 ccaaacagaa gagacatata agaaactctt taaacagatg ctggctttcc aatacggttt
    32341 gaaagccaat gtaaaattaa tagataaaga tctagacact gcttggaaag aattctatcc
    32401 agaagttagt acacagatca ttctattttc gactaaagaa gaagcagata aagcaaaaaa
    32461 agaagcaaat gaaggagaaa atttctccaa gcttgttcaa gcttatggaa aaaataaaac
    32521 attaaaggaa actgatggaa aaatgaattt tgattcaacc aatccagaga ttcctactga
    32581 agtaaaaaaa gcagcattta aactaaaaaa cggggaagtt tctgatatca ttcctgtaac
    32641 agatccaacg acttatcagc aaagctatta tctagtaaaa atggtaaaaa aacaggataa
    32701 aggttctaat aaagacaaat acaaatctga gctagaaaaa attgctaccg aagcaaaaac
    32761 tcttgatacg gaattcatgg ataaaacaat ccgtaaagtg atgaaaaaag acaatgtaac
    32821 tattaaagat ccttatgtaa aaaatatatt caaataaaca aatttgaccc aattggggat
    32881 gtggcaaaat ttgagaagtg atttttggaa attccttctt atttttgagg caaaccactt
    32941 ttgccacaac ttcatcgggg ccttttttta tttgtaccaa aacaaatcac tggatttgtt
    33001 acaatcatga ggatataatt taaaaaagtt ttttatttct atcacatgaa tcaatgcgcc
    33061 attaagtaga ttctttcatg cttccctatt ttttcacttg ccgtatcgct tcaaaaacaa
    33121 ctatcataaa ctcaaactcg actgaaaagt tattttaaaa aagactaaaa atatcccttc
    33181 tggacttgtt cttcttattc tgttatacta gagaaacacg aaagatattt ttatgcgaca
    33241 cttttcattt gtttttatga aatttattca aaactggcgt aacttcagag ttacaaggat
    33301 gtattagagg ttagggaata catcgtttaa atgagaaata agtaatagtt agtaatagtc
    33361 acccaaactt taaattaatg aatattgaat cgtcagatag cctcctcgag ttttcgagaa
    33421 ggctatcgtt tattttatgg agaaattgat tcagaagtaa tcagcgacct tttttagttc
    33481 accaatcgtt tctgcttgga aagtttgcac ccaatcttct tggaagcccc tcactgcttt
    33541 atcaatcgag ggcatctcta atacttgatc tagtagctct ttacctaacg ttatcgcatg
    33601 agctccagat cgaatggctg tagtgacttg ttcacaattt ttgaaactag ctgctaatat
    33661 ttttgttggt ctttgcgtac gttcgatctc agtccgcaac gaatcaatca ctttcatagc
    33721 atcaatgcct tgattttgca tcctgttata ataaggtgca atataatctg ctccattatt
    33781 aatagctaaa tacccttgta attctgtgta aatagctgta ccggtaatca aataaccttc
    33841 ttttttcaac tttttgatcg cttgaaggcc tgcttgattc accggcacct tgataaacgt
    33901 atcttttccc agttcttcta tgataactcg agcatcctct atcatttctt cttccgttct
    33961 tcctattgtc tgaatatgga taggaatctg tccgattatt tttttgattt ctttcatatg
    34021 cgagaagaag tttgacgctc cttctttttt cagaattgta ggatttgttg ttacgcctgt
    34081 taaattcaaa aactgttgac aagaataaat actttttgta tttgctgtat caagcatgat
    34141 ttccatatag ctttccccca ttctgatcct cttgatcgat tttaatgatt gtcccctttc
    34201 ttaaatgcgg catttcctta tcttctacat acattgttcc tggaagttcc ggctcatgag
    34261 atccatcaaa ttttatcgtg atatgtccta attcattcaa attagtttgg acaacatctc
    34321 ctactgctgt gattacatac atttgtttat caaaacagag cttcatatca caagttattt
    34381 cttttcttac ctgattcaat tcaatcttat aacaataatc tgttaatgtt tccggtgctt
    34441 catctccaaa taaaatcatt attttttctt tcctgaatac ttctgcttct ataccaacat
    34501 ctgttacaac cgtttcaaag atcgtcatct ct
//
LOCUS       DAZUJR010000022        34439 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.022, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000022 DAZUJR010000000
VERSION     DAZUJR010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34439)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34439)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34439
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.022"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            342..1031
                     /locus_tag="ACG804_000992"
     CDS             342..1031
                     /locus_tag="ACG804_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFS4831939.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1018..2226
                     /locus_tag="ACG804_000993"
     CDS             1018..2226
                     /locus_tag="ACG804_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFS4831940.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2520..3791
                     /gene="serS"
                     /locus_tag="ACG804_000994"
     CDS             2520..3791
                     /gene="serS"
                     /locus_tag="ACG804_000994"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HFS4831941.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4340..5824)
                     /gene="guaB"
                     /locus_tag="ACG804_000995"
     CDS             complement(4340..5824)
                     /gene="guaB"
                     /locus_tag="ACG804_000995"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HFS4831942.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6329..7024)
                     /locus_tag="ACG804_000996"
     CDS             complement(6329..7024)
                     /locus_tag="ACG804_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HFS4831943.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7114..8214)
                     /gene="ychF"
                     /locus_tag="ACG804_000997"
     CDS             complement(7114..8214)
                     /gene="ychF"
                     /locus_tag="ACG804_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HFS4831944.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8223..8414)
                     /locus_tag="ACG804_000998"
     CDS             complement(8223..8414)
                     /locus_tag="ACG804_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HFS4831945.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8435..9325)
                     /locus_tag="ACG804_000999"
     CDS             complement(8435..9325)
                     /locus_tag="ACG804_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HFS4831946.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9312..10079)
                     /locus_tag="ACG804_001000"
     CDS             complement(9312..10079)
                     /locus_tag="ACG804_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFS4831947.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10091..10804)
                     /gene="rsmG"
                     /locus_tag="ACG804_001001"
     CDS             complement(10091..10804)
                     /gene="rsmG"
                     /locus_tag="ACG804_001001"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HFS4831948.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11036..12937)
                     /gene="mnmG"
                     /locus_tag="ACG804_001002"
     CDS             complement(11036..12937)
                     /gene="mnmG"
                     /locus_tag="ACG804_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HFS4831949.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(12954..14351)
                     /gene="mnmE"
                     /locus_tag="ACG804_001003"
     CDS             complement(12954..14351)
                     /gene="mnmE"
                     /locus_tag="ACG804_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HFS4831950.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14650..15033
                     /locus_tag="ACG804_001004"
     CDS             14650..15033
                     /locus_tag="ACG804_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831951.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15201..15959)
                     /gene="jag"
                     /locus_tag="ACG804_001005"
     CDS             complement(15201..15959)
                     /gene="jag"
                     /locus_tag="ACG804_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HFS4831952.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(15977..16795)
                     /locus_tag="ACG804_001006"
     CDS             complement(15977..16795)
                     /locus_tag="ACG804_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0032977 - membrane insertase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YidC/Oxa1 family membrane protein insertase"
                     /protein_id="HFS4831953.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(16792..17148)
                     /gene="rnpA"
                     /locus_tag="ACG804_001007"
     CDS             complement(16792..17148)
                     /gene="rnpA"
                     /locus_tag="ACG804_001007"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HFS4831954.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17266..17400)
                     /gene="rpmH"
                     /locus_tag="ACG804_001008"
     CDS             complement(17266..17400)
                     /gene="rpmH"
                     /locus_tag="ACG804_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HFS4831955.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            17924..19258
                     /gene="dnaA"
                     /locus_tag="ACG804_001009"
     CDS             17924..19258
                     /gene="dnaA"
                     /locus_tag="ACG804_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HFS4831956.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDIKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19456..20586
                     /gene="dnaN"
                     /locus_tag="ACG804_001010"
     CDS             19456..20586
                     /gene="dnaN"
                     /locus_tag="ACG804_001010"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HFS4831957.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            20815..21057
                     /gene="yaaA"
                     /locus_tag="ACG804_001011"
     CDS             20815..21057
                     /gene="yaaA"
                     /locus_tag="ACG804_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HFS4831958.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21044..22168
                     /gene="recF"
                     /locus_tag="ACG804_001012"
     CDS             21044..22168
                     /gene="recF"
                     /locus_tag="ACG804_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HFS4831959.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDSRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22165..24111
                     /gene="gyrB"
                     /locus_tag="ACG804_001013"
     CDS             22165..24111
                     /gene="gyrB"
                     /locus_tag="ACG804_001013"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HFS4831960.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24131..26602
                     /gene="gyrA"
                     /locus_tag="ACG804_001014"
     CDS             24131..26602
                     /gene="gyrA"
                     /locus_tag="ACG804_001014"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HFS4831961.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            26838..27137
                     /gene="rpsF"
                     /locus_tag="ACG804_001015"
     CDS             26838..27137
                     /gene="rpsF"
                     /locus_tag="ACG804_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HFS4831962.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27187..27699
                     /gene="ssb"
                     /locus_tag="ACG804_001016"
     CDS             27187..27699
                     /gene="ssb"
                     /locus_tag="ACG804_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFS4831963.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27725..27961
                     /gene="rpsR"
                     /locus_tag="ACG804_001017"
     CDS             27725..27961
                     /gene="rpsR"
                     /locus_tag="ACG804_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HFS4831964.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28104..30077
                     /locus_tag="ACG804_001018"
     CDS             28104..30077
                     /locus_tag="ACG804_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HFS4831965.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30083..30535
                     /gene="rplI"
                     /locus_tag="ACG804_001019"
     CDS             30083..30535
                     /gene="rplI"
                     /locus_tag="ACG804_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HFS4831966.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            30809..32176
                     /gene="dnaB"
                     /locus_tag="ACG804_001020"
     CDS             30809..32176
                     /gene="dnaB"
                     /locus_tag="ACG804_001020"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HFS4831967.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            32956..34248
                     /locus_tag="ACG804_001021"
     CDS             32956..34248
                     /locus_tag="ACG804_001021"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HFS4831968.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT        10501 a         6693 c         6824 g        10421 t
ORIGIN      
        1 gtcaacaact tattttttat tatttaataa gttattggtg ttcttttgaa caaataataa
       61 tatatcaaca tcacatgtga aagtcaataa gaaaatgctt atttatcaac atttctagct
      121 tacatgatca ttggttagtt ctggtccttt ttcgttcgtc tttataactc cgagagacgt
      181 aaaatccttt tgttttcagt ttaatgttca tgttcttgtc ttattcacac caactagatg
      241 tctcaccttc taaaattttc cttaacaaag tgctgctttt atctatttct gctttttttt
      301 gctagaataa tagtaacaat atgactctgg aggatttatt tatgaaaatt ttgattgctg
      361 acgatgataa agaaatcgtt gaattattaa gtatctatgt tcacaatgag gggtatgaag
      421 cagtaaaggc ttatgatggg aaagaagcat tatctaaaat cagaacaatc cctgatattg
      481 aattacttat tttagatatc atgatgcctg agatggatgg gatgcaagta gtgaaagagc
      541 tacgaaaaga atcccaaata ccaatcatta tgctgacagc aaaaactact gatatggata
      601 agatcaaagg actggtcgct ggtgcagatg attatgtgac caagccattt aatccgttag
      661 aagtaatggc tagagtaaag tctttattac ggcgtacaaa aatgcagatt gccccagatc
      721 agcctgatgt attagaagta aatgcattaa tcatcaataa agactctcat gaagttaaaa
      781 caatcgatgg gaaagaaatc cagttaacag ctttggaatt cggtatcctc tacttgcttg
      841 ctagtcatcc taatcgagta tttagcgcgg atgaaatttt tgagcgtgtt tggaaacaag
      901 aaagtattgt ctctgctaaa actgtcatgg ttcacgttag tcatttaaga gataagattg
      961 aagaagcaac tggtggtgaa aaagtcattc aaaccgtttg gggagtgggc tataaaattg
     1021 acgcaagata gtaaacgagc aactgaaaaa cgccgtcgga tcaatttgac ttcaaaagaa
     1081 atcagcgaat tgttagcgga aggaatcatc acgattatcc ttttgcttct attaaatgtt
     1141 tctattctgg ttgttatcag ttcggtgatc aacagttcac cttctttgac gaatgcgatt
     1201 tgggattcaa agaatatttt tgcagaacga ttgaacactg atttgttctg gaacggccgg
     1261 aattttatta ttcccttttt ctttctatta gatattggtg ttttgtattg gcgcttgatt
     1321 cgaagatatc gccaaatgca attgcggcat atcatcagcg aacttcacta catcgcaaac
     1381 ggaaattatg atcatcgtat cccttttgaa ctgagtggtg acttaagccg agtggtaaca
     1441 agtatcaatg gattggtgga tagtaccgta gcagcgattg aagacgaacg taaaatcgaa
     1501 aaatcaaaag atgaattgat cacgaatgtc agtcatgata tccgtacccc actcacgtcc
     1561 atcattggat acctaggact gatagaagat ggccagtatc actcagaaga agatctttta
     1621 aagtatacgc atactgctta tatcaaagca aagcagatga aatctttagt ggacgactta
     1681 tttgaataca ctaaggtacg ccagcctgct gtcccggtga atttttctgc ctttgacatg
     1741 atccagttga tcgaacagtt agcagctgat tttgagttgg aagcttctaa aaaaaatatc
     1801 caaatacttg ttcaatcaaa agtagactcc cttatcatgg atggcgatac cgaaaaactt
     1861 gtacgtgtct tcaataatct tttgacgaat gcgttgaaat acggaaaagg agcaacgaag
     1921 atcgtaatcg aagtagaacg tatcggttca gaagttgttg caacagtcaa aaataacgga
     1981 gcaatgatcc cacaacaggc aatcgataat ctattcgacc gtttttatcg tgtagaagaa
     2041 tctcgttcac aagcaactgg aggaactgga cttggtttag caatcgctca aagcattgtg
     2101 gctttgcacg gcggatacat ttatgcaaaa tcagataagc aatggacttc tttcatcatg
     2161 caccttccaa tcaagaaaaa tgaaaaatta cctattgata cacaggaagt tattgacgaa
     2221 agctgaaata ttcgctattc ttattacaat tattagaata aatgaaaaac acagaaccca
     2281 gtacacttta ttctttttca gagagctgat ggcaggtgta aatcagcaaa ggataatttg
     2341 gaagttccag ttcgtttacg tgccctttcg aaataagaaa ggtcggttca acagccgtta
     2401 tgtgttcaac aagtgcagct gacgctgaac ttgggtggta ccgcgaattt cagactgatt
     2461 cgtcccaaga ataatgggat ggatcagtct ttttttattt tcaaaaagga ggaaatcata
     2521 tgttagatgt aaaaatgatg cgacaaaata ttgaagaagt acaagaaaaa ttgatgactc
     2581 ggggcgtaaa aaaagaaaca ttagctgaat tcatggaact agatgaaaat cgtcgtaagc
     2641 tactagtcaa aagtgaagaa ttaaaaaaat atcgaaatga tgtttctgct gagatcgccc
     2701 aattgaagcg tgcaaaagaa gatgcttctg ctaaaatcgc tgaaatgaaa gaagtcggtg
     2761 gcaacatcaa agcattggat actgaaattg ctgaagtgga tgaaaaattg aaacaaattg
     2821 caactacttt gccaaacctt ccccatgatt ctgtgccagt tggaacagat gaagaggaca
     2881 atgtagaaat ccgtcgttgg agcgaaccac gtacatttgc ttttgaacca aaaccacact
     2941 gggaaattgc agaaaatctt gatattttag attttgaacg tggcgcaaaa gtagccggta
     3001 gccgttttgt ctattacaaa ggattaggtg ctcgattaga acgtgctgtc tacaacttca
     3061 tgcttgatca gcatatttac gaacacggct atactgaaat gatcactcct tatatcgtca
     3121 acagtaaagc gatgtttggt acgggacaat ttccaaaatt caaagaagat gttttccaat
     3181 tggagaatac tgatctaaca ttaatcccaa cagctgaagt accattaact aactattata
     3241 atgatgaaat tttagatggt gcagatttac ctatttattt cactgcacta agccctgctt
     3301 ttcgttctga agccggaagt gctggtcggg atacacgagg actgattcgt cttcaccaat
     3361 tcaataaagt agaaatggtc aaattttcgg atgtagagca ttcttacgaa gaattggaaa
     3421 aaatgacagc tgatgcagaa gatatcttga aaaaattgca tttgccttat cgtgtgatgg
     3481 ccttatcaac tggagacatg ggcttttctg cagctaaaac ttatgactta gaagtatgga
     3541 tacctgcaca agatacttat cgtgaaatca gttcttgttc taactgtgaa gatttccaag
     3601 cacgccgcgc aatgatccgt tatcgcgata atgatggaaa aatccactat actcatactc
     3661 tgaatggttc aggacttgca gttggccgta cagtagctgc cattttggaa aactaccaaa
     3721 atgaagatgg ttctgtcaca gttccagaag cgctcgttcc ttatatgggg aatctgaaag
     3781 ttattaaata aagaggctgt gaaaaagccg cttagtttcg agtattaaga aaaattttgt
     3841 gaaaatggct ttccacattt ttgcataaat tggacttaat accgagaaac tggcttttga
     3901 acaccattta tcgagaggtt gtgaaatcag cgaattaacc tgagtattag agaaaaaaat
     3961 ggaaaaatag tccctcatat tttaccgttt gttgaactaa taccgagggt cagctgattg
     4021 aacaccgttt agtggagagg tcgtaagcct accccccagc tcctagttac aaggacaaat
     4081 tcaaaaaaca gctcttcata ttttatgaat gttgtacttg tgattcggag gtggcaaggg
     4141 aacactgttt attcaaaaag aggctgggac agaagcgttt aactccaaga aataagaaga
     4201 aattcacgaa aattgctttt caaatttttg tgaatttctt cttatttccg aaggagttgc
     4261 ttctacttcc gccgtttata cgtgtttaga gcgtgagaca aaagtgttct ttacttttgt
     4321 cccacgctct ttaatgtttt taagattcaa ctgaatagtt tggtgcttct tttgtgattt
     4381 gtacatcatg agggtgtgat tcttttaatc cactgccgct catttggata aattgcgctt
     4441 catcacgtaa ttgctgtaga ttggctgccc caacataacc cattcctgaa cgcaaaccgc
     4501 cgatcatttg gaaaataata tctgcaacac ttcctttata agcaacccga ccttcgattc
     4561 cttctggtac taatttattt gcttcattga cactaccttg gaagtaacgg tcttttgaac
     4621 ctttttccat cgcgcctaat gagcccatac ctcggtatgt tttgaatcga cgtccttgga
     4681 agatttcgaa ttcacctggt gattcatctg tccctgccaa catacttcct agcatcactg
     4741 catgtccgcc ggcagctaat gctttgacga tgtcaccaga atatttgatc cctccgtctg
     4801 caataatcgc tttgccatat tgacgagcaa ctgatgctgc atcataaata gctgtgagct
     4861 gaggtacacc tacaccggct accacacgtg tcgtacaaat cgatcctggt ccgataccaa
     4921 cttttacgac atctacacct gcatcatata aagcttttgt cgcttcagcc gtcgcaacgt
     4981 ttcctgcaat caatgttgca tctgcaaaag ttgaacggat ttcttgaatt tttcggatca
     5041 cacctgcact atgtccatga gctgtatcga tgatgattgc atctgcccct gcttctaata
     5101 aagcattcgc acgctcaaat gtatcgcttg ttacaccaac ggctgctgct acaagcaatc
     5161 gaccatgttc atcttttgct gcatttggaa attcgatcac tttctcgatg tctttgatcg
     5221 tgatcaatcc gcttaaacga ccttcgttat ctacgattgg taatttttcg attttatgtt
     5281 tttgcaaaat cttttctgca tcttttagag aggtacctac tggggcagtc actaagttgt
     5341 cttttgtcat cacatcagca atcggcatgt gataatctgt tacaaaacgc atgtcgcggt
     5401 ttgtaattat ccctaccaat tttctgtttt caagtgtttc aacgattggc acaccactga
     5461 tacgatattt gctcatcaat tcttctgcgt ctgctacaag atgctgcggc gttaagaaga
     5521 acggatcaat gattacgcca ctttcagaac gtttgacttt tcttacttca tccgcttgct
     5581 ggctgatcgt catgttttta tggatcacac ctagtccgcc ttgtcttgcc atagcaatgg
     5641 ccatcttgct gtcggtaaca gtatccatac ttgcactgat gattggaata ttcaacttaa
     5701 tatttttagc taattgtacg ctcatatcca cttcgtttgg taacacgtga ctttctgctg
     5761 gtatcaataa gacatcatca aaagtaaatc cttttttcgt gaactttgtt tcccagttgg
     5821 acatttttag taccactcct ctaatttagt ttatctatta aaataattga ttttttcatt
     5881 taagtcaatg atctacttgg aatcaagtta gctttctcat agaataccaa tataaagcgt
     5941 ttacatctgt gtgtattaaa agagattgta aaaaagctgt cctgcatcaa gtaataagaa
     6001 cagccaatca aaaacagctt ctcatgtttt tgaattggtt gggtttatta ccgcagatgc
     6061 aaacttttga acaccgttta gtggagaggc tgtgaaaaag ctgcttagtt tcgagtagta
     6121 agaaaaattt tgtgaaaatg gctttccaca tttttgcata aattggactt aataccgaga
     6181 aactggcttt tgaacaccgt ttatcgtaaa aagggactgt gacaagactt ttgtcacagt
     6241 cccttactat tatttaacta tggataaaca aaatgaggtt ctttactacc cctagatatc
     6301 tagcaaaata gctgatcttt ttgctagttt atcttcttgg gacggataaa cttccaataa
     6361 tcccgtattt tttcttcaag tagtaacgga ttgctaaagc agttgccccg ataatgataa
     6421 ctactactgg atctaatact ggattgataa ctggtggcaa tagtgttgtc gcagaaaaca
     6481 gtacgaccca aagaagtgtc gttccaccta ggataagcaa tgtcttaccc attcctggtt
     6541 tcttgcttcg atctgctccg ggatattcat attgatagat gtatttgtac atcatataaa
     6601 agacccagcc accgattgca gaacctagaa cgagtgtaga aaagccataa gctggcgttg
     6661 ttccacgtga aaacaatccg gtaatcgcaa tcatgatact taatagacca agcaacagca
     6721 acgtattatc taaccacatc aataaagggg tggatgaatt ttttacttct gctggcttat
     6781 tgatgattgc ttccgttctt tcagagactg tcccaaacaa ttgacgggct gttcttccgc
     6841 ctttttgttc tgcaactaaa gtaggcagaa tgtcatgaag ggcttttact ttttcttctt
     6901 cagacaaatt cgctgcttct aaagattttt tcaaatcaaa aatgtactgt tgatttcttt
     6961 tggttaattt tgtttctaaa ctattgtttt cttttacgat tgctcgtaat tgttctggtt
     7021 ccattatcta atagtcctcc ttagccgttc cttttctcaa cggtcgtcac aaaagacatt
     7081 ctaccatatt ctacagctag tttgatagcc cttttacaca ttaaagcgga ataacattac
     7141 gtcgccgtct tgtacgacat aatcttttcc ttctaatcga acacgtccag cttcttttgc
     7201 tgcatgcatg tttccgtaat gatccaagtc ttcaaaagag acagtttctg cacggataaa
     7261 tccgcgttcg aaatctgaat ggatgattcc tgctgcttgt ggtgctttga ttcctttttt
     7321 gaatgtccaa gcacgtactt cttgttcccc agcagtaaag taagtagcta agcctaacaa
     7381 atcataagca gcacggatca actgatccaa acctgattct tcgattccta aagcttctaa
     7441 aaattccgct ttgtcttctt catctaattc tgcgatttct tcttctgcac gagcactgac
     7501 cacgatcact tctgcatttt cttctgcagc aaagttgcgc acttcttgta cataatgatt
     7561 cgcgtctgca tctgctacgt catcttctga gacattggct acataaagaa ttggttttgt
     7621 cgtcaataaa aatagtgatt taacgatttt ttgttcttct tcagtaaatt cgatcgttcg
     7681 ggcagatttt ccttcttcca gtacaggttt gattttatcc agtacagcta gttctgccac
     7741 tgcatcttta tctttggttt tagcaacttt tgctacacga gtatagcgtt tgttgataga
     7801 ttctaagtct gctaacacta gttccaagtt gatcgtatca atatcttcta gtggatcaac
     7861 acgtccttct acgtgagtaa tattatcatc atcaaaacag cgaacaacgt gacaaatagc
     7921 gtctacttgg cggatatggc ttaagaattg atttcccaaa ccttctcctt tacttgcgcc
     7981 ttttacgatt ccagcaatat ctgtaaattc aaaagtcgtc ggaacagttt ttttcggatg
     8041 tacaagttct gttaagcgtt gcaaacgcca gtcaggtact tctaccatcc ctacgttggg
     8101 gtcgatcgtc gcaaagggat agtttgctgc ttctgctcct gcttttgtga tcgcattaaa
     8161 caaagttgat tttcctacgt tgggcaaccc aacaattcca gcagtcaatg ccataaattt
     8221 attcactctt tctctgcatt tttttcaatt acttttttta atttcttttc aaaatctcga
     8281 cgggtcatca tgacgatatg tccgcaattc atacatctga ttttgatatc tgcgcccatt
     8341 cgaatgactt cccagcgatt cgtctggcaa gcgtgaggtt ttttcatttc aacgatatcg
     8401 tgcaagtcgt acataaaaat agcctccttt ttgtttattc ttcatcaaat tgaatattca
     8461 agatatcaag aattcgagtc aaatcttttt gagaaagata ttcaatctcg atcttacctt
     8521 tcccattttt ttcttggata gctacacttg taccaaattt atccatcaaa cgatcttcgc
     8581 tttctcggat ataatatggt ttttcctttg ctagccttgg gatttttttc ttttcttttc
     8641 catcattttg atttaactca gaaacaagct gttccagttg gcggacagtt aaattttcag
     8701 ttactgcacg attggctaat ttcaagatca atgttttatt ttttaaacct aacagcgtac
     8761 gggcttgtcc catagataaa cgctgatctt gtaccatttc cttgacaaga tccggtaaag
     8821 aaagcaagcg caaataattg gcgatataag gtctgctctt tcctaaacga ctagctactt
     8881 ctgcttgtgt tagtttcagg tttttcatca gcatctcata tgcttctgct tcttctaacg
     8941 gattcagatc ttctcgctgc aagttttcca gcactgctac ttgcatcatc gcttcttcgt
     9001 caaagtctct aacgatagca gggatcgttt ctttttcagc tagtttggac gctcgaaaac
     9061 gtcgctcccc tgcaataatc tcatatcctt ttactgcgga acggcgtacg atgatgggtt
     9121 gaaagacacc tgattgttca atagaattag ctagttcctg caaagatact tcttcaaatg
     9181 ttttacgggg ctgatacgga tttggtcgca gctcattcaa tggtagctgg acaacggtat
     9241 catcttttac atccaccgtc tctaagtttt ctaaatcttg aaacagtgca tcgattcctc
     9301 ggcctaatcc tttacttttc ttcacgactt accacttcct ttgccaatgc ttggtagact
     9361 tcagctcctc gagaacgtgg atcgtagtcg atgatcggtt ttccatgact aggtgcttct
     9421 gataaacgaa tatttcttgg aatgatcgtt tcgtaaactt tttcgcggaa gtatttacgt
     9481 acttcttcta cgacttcatt tcccagattt gttcgtgcat catacattgt cagtaagact
     9541 ccctcgatct ctaattctgg attaaagtgt ttttggacta aacgaaccgt attcagtaat
     9601 tggcttaatc cttccaatgc gtaatactca cactgaacag gtatcaaaat cgaatcactt
     9661 gctgtaaatg aattgattgt cagatggcca agagaaggcg ggcaatcgat caaaatataa
     9721 tcatactgac tgcttacttc tgctaaagat ccttttaatc ttgattctct tgccatcatt
     9781 gacgtcaatt cgatctctgc tcctgctaat tggagagtcg caggcacaat actcaaattt
     9841 tcgtgttcag tgatcaaagt tgcctcatca attggcaatt cattgactag aacatcatag
     9901 atgtctcttg tcacatcagg ttttctgatc ccgacaccac tggtagcatt tccttgtgca
     9961 tccatatcca ctagcaatac ttttttgcca aggctagcaa gacaagcacc tagattcacc
    10021 gtcgtcgttg ttttgccgac gccacctttt tggttcgcaa cagatattat ttgtgccatc
    10081 tcttctcctc ctatttgatt ggctgcttat taggcagtcc gggctttctt gggtatttct
    10141 ttggggttgg tttctttttt tgaataacga tgatatgccg ttgatcagag acattcggca
    10201 aggtaaccgc ctcttctttg aggaatttac cacctaataa agcaatcgct tgttttgctt
    10261 ctgtcaattc ctcttcactt tttgctgctt tcaatgcata aaaatagcct tcttgtttag
    10321 ccaagggcaa acacaattcc gctaacacat tcaaacgagc aaccgcacga gcagtgacaa
    10381 ggtcaaatga tgcacgaaag tgaggatttt gcccaaatgt ttctgcccgg tcatgatata
    10441 aggaagcatc gattcctaat aatcgggtta actcagataa gaaggttatt cgtttattca
    10501 gagaatcaac gatcgttatc tgcagttctg gaaaggcaat ttttaaaggt atgctaggaa
    10561 accctgcccc cgaaccaaca tcgcataaag ataaaggttg cgtaaagtct acttcaaatg
    10621 ctaatgtaag tgaatcgtaa aaatgcttca gatatacgtc tttttcatcc gtaatagctg
    10681 taaggttcat cttttcgttc cattcgacta atgtccgata ataaatagcg aattgattca
    10741 tttgatgatc ggtaagctct atcccttttt ctgccaagga ttggcgaaat tcttctggta
    10801 tcataaatat tcctttcatt gtgaaacagc aattgtttca cagattctct ccctacttta
    10861 acgcaaaatc tctagacatg caatccttcc atatggattc ttaaaaattt gaaaagtaag
    10921 aaaagccgat agactttttc tttctagtat gactcataaa atatacacag aagagagaac
    10981 tagctttgag caatttctgc aaaaactagt tctctcttct atttattatt acgtattacg
    11041 ctggttcact gactttcgca atcttccctt gttcgatata gaccattagg atacttaggt
    11101 ctgcagggtt tacgccactg attcggctag cttgggcaat tgtttctggt tggattttct
    11161 gcaatttttg ttttgcttct gttgctaatc cgttgattgc tgcgtagtcg atgttttctg
    11221 gaatcttttt cgcttccatg cgttttaatt tttctacttt ttccatggct tttttgatgt
    11281 agccttcata tttgatttgg atttctactt gttcgatttc ttttcgtgtc aattcttcat
    11341 tttctggaat aaaccgtaga agttctgcat aagtaatctc aggacgtctt aaaaagtcgc
    11401 ttgctagtac accatctttt aatggtgccg cattaatcgt tgctaaaaag tcttggactt
    11461 cttctgttgg tttgattcgt acattcatca aacgtttgat ttcttgttca actgcttctt
    11521 ttttcttcaa ataattcttg tattgatctt cttttactaa gcctacacgg tgacccattt
    11581 ctgttaatcg caaatctgca ttatcatgac gtaaaagcag acggtattca gcacgtgaag
    11641 tcagcaaacg ataaggttcg ttcgttcctt ttgttaccaa atcatcgatc atgacaccga
    11701 tgtaaccgtc acttcgtttg atcactaaag gttcttttcc ctgaactttc aaagctgcat
    11761 tgataccggc aatcagccct tgtccagccg cttcttcata accgcttgta ccatttgttt
    11821 gtccagctgt ataaagattt tcaacgactt tagtttctaa tgtcggacgg agctggtgtg
    11881 gctctactac gtcatattcg atagcatatc ctgtacgcat catttctact ttttctaatc
    11941 cagcaataga atgaagcatg ttgacttgaa catcctctgg taaagaagta gataaacctt
    12001 gaacatagac ttcttccgta tttaagcctt ctggttccaa aaataattga tgacgtggtt
    12061 tgtctgcaaa acgcacgatc ttatcttcga tggatggaca atagcgagcg cctacccctt
    12121 caacgatccc tgtaaacatt ggggcacgat gtaagttgtc tcgaataatt tggtgagtcg
    12181 tctcacctgt ataggtcagc cagcaagatt cctgatctag tttataggca ctatctggtg
    12241 tgctgaagct aaaatgattc ggctctttgt caccaggctg ctcttctgta acagaatagt
    12301 cgatcgtact tgattttact cgaggcggtg ttcctgtttt gaaccgttcg atagcaaagc
    12361 caagttcttt tagatgattc gctagtccaa tagaaggttg agagttattc ggacctgatg
    12421 aatatttcaa ttcaccgata atgatttctc cgcgaagtgc tgttccggct gtaataacaa
    12481 ctgctttggc ccggtagctc gctcctgtgg acgtcactac tccatgacaa acaccatctt
    12541 cgacgatcag ttcttcgacg attccttgtc ttagcgtcaa atttggttct ttttcgatcg
    12601 tatgtttcat ttctgttgaa taagcatgtt tgtctgcttg tgctcgcaat gctcggacag
    12661 ctgggccttt tcctgtgttc aacatacgca tttggatata ggttttatcg atattcttac
    12721 ccatttctcc gcctaacgca tcgatttctc gaacgacaac gcctttagct ggtccgccta
    12781 cagaaggatt acatggcatg aatgctacca tgtccaaatt tattgtcagt aataatgttt
    12841 ttgatcccat acgtgcagca gcaagtgcag cttctgaacc ggcgtgtcct gcgccaacaa
    12901 cgatcacgtc atacgcatct gcttcataat gttccaatcg tttgttcctc cttttatttt
    12961 cctaaacaaa attgactgaa taattgagtg attagctcat cttgtacact gtcgccgaca
    13021 acttctccta gatagtccca gcaacgcgtc atatctattt gaacgagatc cacaggcatt
    13081 cctgaatcaa tacctgcaat gacttcttca agtgagaggg aagctttttc taacaacgcg
    13141 atatggcggg tattagaaac ataagtagcg tctctttctc ctgtttctcc gctgaagaat
    13201 aaatcagaaa tagctgattc caaacgatct agtccgtcgt ttttagctac ggaaattgaa
    13261 aaaactggtt cattttcgat caatttcttc aatttttctt gttccagctg tgctggcaaa
    13321 tctgttttat ttagaagaat gatccgtttc aatccacttg tcgcttccaa taattgttca
    13381 tcttctgctg tcagtggttc gctttggttt agaacaagta agatcaagtc tgcttctgct
    13441 aatgcttttc ggcttctttc gaccccgatc cgttccacca catcttctgt ttcccgaatt
    13501 ccagctgtat cgattagctt gagcggtacc ccccgaacat tgacatactc ttcgattaca
    13561 tctcgagtcg ttcctgcaat atccgtaacg attgcttttt cttctcttaa caaatggttt
    13621 aacaaacttg atttgccgac atttggccgg ccgatgattg ccgtacttaa cccttcccgc
    13681 agaaccttcc cttgcttgga tgtagcaagt agcgcttgga ttctttgttg gatcatctgc
    13741 gctttttcaa gcaataactt cgtagtcaat tcttcgacat catcatattc tggataatca
    13801 atatttactt ctacttgtgc taatgtctct aaaatctctt gtctcaatga gcggatcaaa
    13861 gcagacagat tgccgtctaa ctgattaaga gctagtccca ttgctttgtc tgtttttgcc
    13921 cgaatcaaat ccatcacagc ttctgcctgt gaaaggtcaa cacgaccatt caagaatgct
    13981 cgttttgtga attcgcctgg ctcagctaat cttgcacctt ctcttaacaa tagctgcaaa
    14041 atttgattga ctacaacgat cccaccgtga caattgattt ctactacatc ttcccgcgta
    14101 aatgtctttg gtgctctcat cacggagacc atgacttcat cgacaagctg attgctcttg
    14161 ggatcaacga tatgtccata atggatcgta tgacttggta cttctgataa tcgtttgttt
    14221 ccagattgat aaactttatc tgctagttgc acagcttgat cgccacttaa acgaacgata
    14281 ctgattgcac cttctccagg tggggtagaa attgccgcaa tcgtatcaaa ttctaaagta
    14341 atttcagcca ttttttcact tcctttttca ttttgcgcac aaaaaaagtg cccactccac
    14401 cctttatgca caataaacgg tgaacttcgc actttgactg cttgttcttg attaaattct
    14461 ggtcatagat tatcacactt gctataagga atcaagtgtt taaaacaatt agatgaagtt
    14521 gagcctgttc tgcttccatt accttatatt taattgtcct tggatgtctc tttgcgttct
    14581 ttggtttatt cgaagagaag atactgtata aacaaggctt tatctttctt aaaaaaaacg
    14641 gtacactaaa tggtagcgct atctaaacta tacacttttg aaaggagaaa atatgtgagc
    14701 ccgttcagat ctgctgcatt ggaagaagaa agtgaccctc ggatcaacga tgtcgtttta
    14761 tctacaggga atatcaacca gaaatatatc gtccgcgata tcgtttttgt tgtggaatgc
    14821 ttagaagctg atttgtttga cccatctttt cccaaagatg accttttctt aacaacgaag
    14881 aggaaattaa agacgaaggt acttgaatat ggtgcgaatg cagtaatcaa ctgtcatttt
    14941 gagtatcagc aaaaaaaacg cgacggaaag tattttctgg aactttttgc ttatggaaca
    15001 gtgatccaat ttatccaaac aacgattggt taaatgaaac agacaaaaaa agcggatcaa
    15061 aactgaagac agtttcgatc cgcttttttc tatcaaagtt agtgactact tcatcgtata
    15121 ctctgataag aatgatttct agtaaaatat acttggtttg aaaaactttg tcaacgtgat
    15181 ttattcaaaa agtaatggaa tcaataatat tttttagcag gttctactac taaataacga
    15241 taaggttcct caccttccga atgtgttttt acatgttcat ctttgcttaa tgcagcatgg
    15301 atttgtttac gttcaaatgc aggcattggt tctaagaaaa caggctgccc tgtccgtttt
    15361 actttttcag ccgtgcgatc agctaaacgc tgaatgatct cttggcgctt ttcacggtaa
    15421 ttgcctacat tgactactac agacagctta tttcttgcta aacgatggat gaagacttgt
    15481 gccagatatt gcaatgcatt cagtgttttt ccatgtttcc caatcagtat gccttgcttt
    15541 tgtgtttcta aatggaaaac aaccatatta tttgattctc tttccatttt gacaagagct
    15601 ggagcatcaa gctgttttga aatttcagta agataaactg ccaattccgt taaagctgct
    15661 tcatcaccta gctcacttac ttcttctgtt ttttcttcaa gaatcgtttc gttgactacc
    15721 tcgatctcag ctgttggttc ttcttccaaa atttcttcta cagtctgttc tactgtttca
    15781 gaaacttttt cgctgatact tggctggatc gaaagccgtg cattctttcg acccattcct
    15841 aggaaacctt tttttccttc ttccagtatt tcgatttcga cttggtcttt ggccaaaccc
    15901 aaatcagcca gacctagttg gacagcttcg tctattgttg cagcttcata aatcggcatt
    15961 agcattacct cccctattat ttccgttttt tcttaggatt cattgctttc ttaagagcac
    16021 gttctctttc gcggattctc cgtgcttctt cttcacgctc ttttcgaatt ttgaaagggt
    16081 tgttgatcag cagcgtttgt acaacttgga aggcattgga aactacccag tataatgaaa
    16141 gaccgctggc taaattgaca cccatcacta aaatcattac aggcatcacg aaattcatga
    16201 tcttcattga tgcattcgat tcaatttgac tcatgctaga taaatacgta cttgcaaaag
    16261 taaagattgc tgctaaaatc ggcaaaataa atgttggatc cgcgttccct aagttcaacc
    16321 ataagaaatg cccttgtttc aactctggta cacgtgaaat agattgccat aacgccatca
    16381 agattggcat ttgtactaat aaaggaagac aaccagcata tggattgacg ccattttctg
    16441 catataaacg ctgctgctct tctcttaact tactttgtgt ttccggatct cttgaactat
    16501 attgttgctg cagtgctttt aatttcggtt gtaattcttg cgttttacgc atgctctttg
    16561 tttggaaatg catcaacggc aataggatca cgcggatgat cagtgtaaat aaaatgatcc
    16621 ctatccctgc attaccaaat gacaacgcct tgatcgcctc agcaaagtaa taaacaatat
    16681 aacgatccca aattcctgta ctctgtgcgc tgacttcccc agttccgcaa ccggataaga
    16741 cgatgaccaa actaacgata ccggccatca aaagtaaacg tttgtatttc ttcacttact
    16801 cttttcctct ctgtcgatta tttttgcaag ttttaagacg tggactaaat tggagcgaac
    16861 ctcatcataa gtcaacccct tcacacttgg tctagcaatc acaataaaat ccaactccgg
    16921 atcaatttct tcttttatag aataaactgc tgctcggatt tttcgtttga cttcattgcg
    16981 gtttaccgcg ttgccgacct tttttcctac agataaacca actcgaaaat gaggctgtcc
    17041 cggtttttcc aaacggtaaa cgacgaattt gcggttagca aaagaatctc ccgtatggaa
    17101 cacggcttga aactctcgtt ctttttttac tcgatacgct tttctcatta gttttctttc
    17161 cttttctatc tctcacttac gctcataatc ataccataat tacgattgtc ctttcatcat
    17221 ttccctaaaa aagagtataa aaaaaaccac tgaaacccca gtggcctaag ctgaaagaac
    17281 ttttcttcct ttgcgacgac ggctagctaa cacacgacgt ccatttttag tactcatacg
    17341 tttacggaat ccgtgaactt tttgacgttt acgtttattt ggttggtatg ttcttttcat
    17401 atattccacc tccaaaatgt tcttatctat tttataaaca cagacatact ttgatagtat
    17461 aacgacaaag tagtgatttt gtcaatataa aatagaagat cgattgttaa aacttatcca
    17521 caagattatt tttttctatg ggagtcctat gtggaaaaag ttatgcacag ggattatcca
    17581 cagataataa atggctggtt ttacacagaa aacacacgtg taaaaaaagt aatccacaat
    17641 caggtgattt cctgtgtatt ccgtctccta actattggta tatctatatt ttttatccac
    17701 agatgcaaga ggaaatctat tgatttttac gagttttcca cctgtgcatt agtggtgtgg
    17761 aaaacttttt tttgacaact gtgtttttct cttttttctt tttgtcgatt gtgtggataa
    17821 ttgtaattaa aaaatttttt tcttcggttt ctgtggaaaa ctattgaaaa aaatgctaaa
    17881 ttagtactag ttattcactt tttaatgaag gaggaggcct tatatggtat ccctcgatgc
    17941 tttatggaat gaattaaaag caacatacca aaaggattta tcgcctgcta gctataatac
    18001 atggatcgaa acagcgaacc ctcgaaccct tgatcaaaac cagctcgttg ttgaggttcc
    18061 tagcaagatt cataaagaat attgggaaaa aaacctggcg acaaaaatcg ttgaagtcgg
    18121 ttatatgtta tcaggaaatg agattatccc tcgctttatt actggcgaag aagcagagca
    18181 agaagaagtt atagaagaaa aaaatccaaa agttgtggca cctagtccgc taaaaaaagc
    18241 catgctgaac cctaaatata cctttgatac gtttgtcatt ggtaaaggaa accagatggc
    18301 tcatgcagca gcgctcgttg tagcagaaga tccaggttct atttataacc cgctcttctt
    18361 ttatggaggc gtgggacttg gtaagactca cttgatgcat gcaattggtc atcaaatgct
    18421 gcaaagtcag cctaatgcca aagtaaaata tgtaagcagt gaaacttttg ctaatgattt
    18481 catcaattcg atccaaaaca aaacagcaga agagttccgt caagaatatc gaaatgttga
    18541 tttactgcta gtggatgaca ttcaattttt tgcagaaaaa gaagctacgc aagaagagtt
    18601 tttccatact ttcaatgcct tgtacaatga agggaaacaa atcgtactaa ccagtgatcg
    18661 gttgccaaac gagattccga aactgcaaga acgcctcgtt tctcgctttg catgggggct
    18721 gtctgttgat attacaccgc cggatcttga aacaagaaca gcgattttac gtaaaaaagc
    18781 ggcggctgaa cgtctagaga tcccagatga cacactaagc tacatcgcag gacaaattga
    18841 ttctaacatt cgtgaattag aaggtgcgct tgttcgagtg caagcttttg ctgcgatgaa
    18901 tagtgaagat atttcgacta gtctagctgc agacgcactg aaaacgttaa aatcaggaaa
    18961 aggacatcct caattgtcaa tcctgcagat ccaagaagaa gtggcaaagt attatcacat
    19021 ccaattgaaa gatatcaaag gaaagaaacg cgtcaaatct attgttgttc ctagacaaat
    19081 cgctatgtat ttggcacgtg agctcacaga taattcttta ccgaaaatcg gagctgaatt
    19141 cggtggcaag gatcatacaa cggttatcca tgctcatgaa aaaatccagc agctgatgga
    19201 ttctagtgtc agtatgcaaa atgaagtatc agaaatcaaa aactttttac taaattaatt
    19261 tgtcgattct atcaactgaa aatagcatgt ggataaaaga aaaaaacgtt caaaagttat
    19321 gcacactttt tccacagctg ttttttcgtt tctctcttac gttttttgag ttttccacag
    19381 aatcaacatg ccctattact tttattattc tttttaacta ataataaata aacaaacatt
    19441 caaaggagat acatcatgaa agttacttta aaccgagcta gctttatgca ggaattgcaa
    19501 actgttcaac gagctatttc aagcaaaacc acgatcccta ttttgacagg tgtaaaaatc
    19561 acactgacac aagaaggttt gactttgacg gggagcaacg ctgatatatc aattgaaact
    19621 tttttgtctg ttgaaaacga aaaagcaaat atgcaaatcg aatctactgg ttccattgtt
    19681 ttacaagcac gtttctttag cgaaatcatt cggagacttc ctgaagaaac atttacttta
    19741 gaagttttag aaaataaaca agtagcgatt acttctggaa aagcgaattt tatcgtaaat
    19801 ggattagatg cagataacta tcctcatctt cctgttgtcg aaagccataa ccagatgaaa
    19861 ttacctgtac acgtattgac taaactaatc aacgaaacag tttttgctgt ctcacaacat
    19921 gagagtcgtc caatcttgac aggtgtgcat ttcattttat ctgataattc tttattggct
    19981 gtagctactg attctcaccg tctaagtcaa cgcgtgattc cagtagaaca agcggctgat
    20041 cattttgata ttgttattcc tggaaaaagt ttgatcgaat tatctcgctc attaacaaat
    20101 gaagaagaaa tcgtcgaaat cagcattatg gaaaaccaag tgttgttcaa aacagaaacg
    20161 atgtatttct attcccgttt gctagaagga aactatcctg ataccaatcg tttgattcct
    20221 tcaagtttta atacagaggt tgaattttct gttcctagct ttttagcggc gatcgaacgg
    20281 gcttctttac tttctcatga aggccgtaac aacatcgttc gtttatctat tcgtccagat
    20341 gcggttgttt tatacggaaa ttcgccagaa atcgggaaag tagaagaaag cttgagttat
    20401 acagcaagca gtggcgatcc attagatatt tctttcaatc cggattatat gaaagcagcg
    20461 ttgcgtgcat ttggagatat gagcatcaaa gtgaaattta tctctgctat tcgtccattt
    20521 acattggaac caacggaaga tggcgttcaa tttattcagc tgattactcc tgtacgtaca
    20581 aattaacaat gattttcatt gttcttgaaa atttaattga aaagaaatag aaaaaataaa
    20641 attttaaaca gaaggcccta aaatctcttt taaggctttc tgtttatttt tgtttaaatc
    20701 acctttttta gattaaatcg tcttatatgg aaaaatatat ggataaattt gttttattgc
    20761 gaaaaaaaag gtataataga gtatactttt aataatgaaa atgagggatg ggcattgaaa
    20821 caacaagtca ttctaaatac ggaattcatg acgttgggcc aaatgttgaa agaagtcaca
    20881 gttatcggta gtggcggaca agcaaaatgg tatttggcag aaaacactgt gttagtcgat
    20941 ggcgaaccag aaaatcgtcg tggacgcaaa ctttatcccg gcatgatggt tgaagttcca
    21001 gaagtaggaa ctttttttat ggtaaaaaaa ggaaacgacg ataatgaggc tgaataagct
    21061 gtatttaaaa aattatcgaa attacgaaga gctgaacatc gaattttcca agaacctcgt
    21121 catcttttta ggagaaaatg cgcaaggaaa aacgaatctt ttggaaagta tctacgtatt
    21181 agctatgacg cgaagtcatc ggacaagtag tgagcaggaa ttgattggct ggactgacga
    21241 tcaggcgatg attcaaggag agatcacaaa aggttcatcc actcttccat tagaaatctt
    21301 attatctaaa aaaggccgaa aaaccaagat caaccatatc gaacaaaaaa agttaagtac
    21361 ttacgtggga caaatgaatg tcattttatt tgcaccagaa gatctttctt tagtaaaagg
    21421 cagcccgcag atcaggcgga agtttttaga tatggaatta ggccagatca atccaatcta
    21481 tctttatgat cttgtccaat accaagcaat tttgaaacaa agaaaccagt atttaaagca
    21541 attgaatgaa aaaaaacaaa ctgatttgct ttatttggat attttgtccg aacaactagc
    21601 agcgtttggc agcaaagtat tgaaagcaag agcacagttc gtcaagcgat tggagttttg
    21661 ggctaattct ttgcatcagc aaatcaccca tcaaaaagag cagctggaaa tcgagtatct
    21721 caccgcagtc gattctttag aaacacatac gcaagagcaa atccaagaac aatttctcgc
    21781 acttttgaac caaaataaaa agaaagacct ttttcgggga acaacgacag ttggtcctca
    21841 tcgtgacgat ctttcctttt ttattaatca gaaaaatgtg cagacttatg gatcgcaagg
    21901 acagcaaaga acaactgcac taagtgtcaa attagcagaa atcgatttga ttaaagaaga
    21961 gacgggggaa tatccaatcc ttttgttaga tgatgtgatg agcgagctgg atgatagtcg
    22021 tcaactccat ctgctagaaa caatcgaagg aaaagttcaa acgttcttaa caacaacgac
    22081 acttgaccat gtaaaaaata aaatgactgt tgaacctgag attttttatg ttcaacaagg
    22141 gaaactaaaa ggagaagaaa ctgaatgaca gaagaaagaa gtttagtaga acgcgctaaa
    22201 gagtatgatg ccagtcagat tcaagtactt gaaggacttg aagccgttcg taaacgacct
    22261 ggcatgtata tcggttcgac tagttctgag ggtctgcatc accttgtttg ggaaattgtc
    22321 gataattcga tcgatgaagt attagcaggt tttgcaacga aaatccatgt gattattgaa
    22381 aaagacaaca gtatcaccgt tattgacgac ggtcggggga tacctgtaga tatccaggca
    22441 aaaactggac gtcctgcagt tgaaacggtc tttactgttt tacatgctgg aggaaaattc
    22501 ggcggtggtg ggtacaaagt ttctggtgga cttcacggag taggatcttc tgttgttaac
    22561 gcgctttcta cacagcttga tgtcaaagta tacaaagaag gaaatgtgta ctatcaagaa
    22621 tatcgtcgtg gagctgtagt ggacgactta aagattatcg aacaaacgga tcgccatgga
    22681 acaacggttc actttacgcc agaccctgaa atttttacag agacaactga gtttgatttt
    22741 tcaaaattgg ctacccggat ccgtgaactt gctttcttga accgcgggat gcgtatatcg
    22801 attgaagaca aacgagaaga agaaccagtc atcaatgaat accattatga cggcgggatt
    22861 aaaagttatg tcgaatactt gaatgcaaac aaaaccgtga tttttccaga acctgtatat
    22921 ttggaaggtg aacagcaaga tatcgcagtt gaagtctcta tgcaatatac agacggctac
    22981 cattccaata tcatgagttt tgccaacaat atccatacgt atgaaggcgg aacacatgaa
    23041 tcaggattca agactgcttt aactcgtgtg ataaatgatt atgcccgaaa acaaaagctg
    23101 atgaaagaaa atgacgacaa cttgaccggt gaagacgtgc gagaaggatt gacagctgtt
    23161 atttctatca agcatcctga ccctcaattc gaaggacaaa caaaaacaaa attgggcaat
    23221 tccgaagtac ggacagtcac tgatcggtta tttagcgaac atttcatgaa attcttgctg
    23281 gaaaacccaa gtgtgggccg tcaaattgtt gaaaaaggat tactagcttc cagagctcgt
    23341 ctagcagcga aacgtgcgcg tgaagtaacg agacgtaaag gtgctttaga gattagtaat
    23401 ctgccaggaa aattagcgga ctgctctagc aacgatcctg aaaaatgcga attgttcatc
    23461 gtcgaaggag attcggccgg cggatcagct aagcaaggtc gtaatcgaga gtttcaagcc
    23521 atcttgccta ttcgtgggaa aatcttgaat gttgaaaaag caagcatgga caagatcttg
    23581 gcaaatgaag agatccggtc tttatttact gctatgggta cagggtttgg agaagatttt
    23641 gatgtatcga aagctcgcta ccacaaatta gttatcatga ctgatgccga tgtcgacggc
    23701 gcgcatatcc gtacattgct gctgactctt ttttatcgtt acatgcgtcc tattgttgaa
    23761 gctggatacg tctatattgc tcagccacct ttatacgggg taaaacaagg gaagaatatt
    23821 acgtatgtac aaccaggaaa aaatgcagaa gaagagttga aacaagtcgt tgcttcactt
    23881 cctgcctcac caaaaccaag cgttcagcgt tataaaggac ttggagaaat ggatgatcat
    23941 caactatggg aaacaactat ggacccaagc aatcggatga tggcccgcgt cagtgtggac
    24001 gatgctattg cagcagatca gatatttgaa atgttgatgg gggatcgagt agaaccccgt
    24061 cgtgcattca tcgaggaaaa tgcacactat gtgaagaact tagatattta atcatgaagg
    24121 aggaaaaaga atgagtgaag aaatcagaga aaacatccat gatgtcaatc taaccagcga
    24181 aatgaaagac tccttcatcg attatgcgat gagtgttatt gtcgcacgtg cacttcctga
    24241 tgtcagagat ggtctgaaac ccgttcatcg ccgtatttta tacggcatga acgaattagg
    24301 tgtaacaccg gataaagccc ataaaaaatc tgccagaatc gtcggagatg tcatgggtaa
    24361 ataccatcct catggagact atgcgatcta tgagtcaatg gtacggatgg cacagccatt
    24421 cagctaccgt tatatgctag tggatggtca tggaaacttt ggttctgttg acggtgacgg
    24481 tgccgccgct atgcgttata ccgaagcacg gatgagcaaa atcgctacag aaatgctgcg
    24541 tgatatcaat aagaacactg ttgatttcca aagcaactat gatgatacag aaaaagaacc
    24601 agttgtacta cctgctcgct tcccgaatct tttagtgaac ggaacaacgg ggatcgccgt
    24661 aggtatggcc acgaatatcc cacctcataa cttgtctgag gtagtagcgg ctatcgattt
    24721 gctgatggat aatcctgatg tgacgaccaa tgaattgatg gaagtattac ctggaccaga
    24781 ttttccaaca ggtggtttgg ttatgggaaa atcaggaatc cgaagagcgt atgaaacagg
    24841 taagggttct attaccgtac gtgcaaaagt tgagattact gagatgccaa atggtaaaga
    24901 acggatcatc gtgacagaat tgccttatat ggtcaataaa gcaaaattga tcgaacggat
    24961 ttctgaactg cacagagaca agcgtatcga agggatcaca gatttgcggg acgaatcttc
    25021 ccgtgaaggt atgcggatcg tcattgacat ccgtcgtgac gccagcgcat ctgttatctt
    25081 gaataactta tataaattga catccttgca aaattcattt ggattcaata tgttggcgat
    25141 cgaaaaaggt gtgccgaaag ttttgagctt gaaacaaatt cttgaaaact atatcgaaca
    25201 tcagcgcgaa gtcatcacaa gacggacagt ctttgaaaaa gaaaaagcag aagcaagggc
    25261 acacatttta gaaggtttgc gtattgcttt ggatcatatc gatgaaatca ttgcgattat
    25321 ccgcgggtct aaatcagatg acgaagcaaa agcgacgatg atcgaacggt tcgatttatc
    25381 cgatcgccag tctcaagcta ttttagatat gcgtttacgc cgattgaccg gtttggaacg
    25441 ggaaaaaatc gaaaatgaat accaagaact cttaaaactg attgaagatt taactgacat
    25501 tctggcaaga ccagaacgtg ttacagaaat catcaagaat gaattagcag acttgaatca
    25561 acgatttggt gataaacgac gcacagaatt actagtcggt gaggtcttaa gtctggaaga
    25621 tgaagattta atcgaagaag aagaaatcgt tattacattg acaaacaatg gttacatcaa
    25681 acgtttggca aataatgaat tcagagctca acgaaggggt ggacgtggtg tccaaggaat
    25741 gggtatccac aatgacgact tcgtcaaaaa tctggtttct tgttctaccc atgatacatt
    25801 gttattcttt acgaataacg gaaaagtgta tcgggcaaaa ggatacgaaa ttccagaata
    25861 cgggcgcaca gccaaaggaa taccaattat caatttacta ggtatcgatt cgagtgaaag
    25921 catccaggca atcattgcgg tgacgggaga agcagaagaa ggccactatc tcttctttac
    25981 gacgcgtcaa ggtacagtaa aacgtacttc tgtcactgct tttgctaaca tccgaagtaa
    26041 tggtctgatc gcaattggtt tgaaagaaga cgatgagctc gtcaatgtgc tactgacaga
    26101 tggtcaatct aatatcatta ttggaacaca taacggctac tctgtcactt tcaaagaaga
    26161 agcagtccgc gatatgggac gtacagcttc cggggttaga ggaatacgcc tgcgtgagga
    26221 agattatgtc gttggggcag ccttaatgaa ggaagatcaa gaagtattag tgatcacaga
    26281 aaaaggttac ggaaaacgga caaaagtatc ggaatatcca gtgaaaggcc gcggaggtaa
    26341 agggatcaaa acggcgaaca tcactgaaaa aaatggtcca ctagctggat tgaccactgt
    26401 ttctggagat gaagacatca tgctgattac agataaaggt gtcattatcc gtttcaacgt
    26461 atcgactgtt tctcaaactg gacgttcaac attaggcgta cgtttgatga agatggaagc
    26521 tgatacgaaa gttgtcacga tggcagcagt cgaaccagaa gctgcagaac aaacagttga
    26581 agaacaagga tcagaagaat agccatcaag actaattgtg taagctagca agaatgaccg
    26641 attaaaaaat ctggttattc ctgctggctt ttttgattag ttgaatttct cttaaaatat
    26701 tcgaaactgt tcattctgta ttgcttttga ccaaaataga gtgtataatc agagcttgtg
    26761 agtagtctaa ttaattagat aactctcctt gctcttagga acctaagagc cgaaagtcca
    26821 cagggaggtg aatatcaatg gaaaacacga aatatgaaat catgtacatt attcgtccaa
    26881 acattgatga agaagcaaaa actgctttaa tcgaacgttt cgatgcaatc ttgaaagata
    26941 acggagcaga agttatcgaa tcaaaagatt gggaaaaacg ccgtttcgct tatgaaatga
    27001 acggttaccg tgaaggtatc tatcacatcg ttaaagtatc ttctccatca tcagcaaatg
    27061 ctgtcaatga atttgaccgt cttgctaaaa tcaacgacga tatcattcgt cacatgattg
    27121 ttaaagaaga agcttaattg ttgtttcatg tgaaacaata gaaaacgatg agaggagatg
    27181 actattttga ttaataatgt tgtattagtt ggacgtctga cgaaagatcc agatttgcgt
    27241 tacacagcaa gtggtacggc agtcgcaaca tttactttgg ctgtgaatcg taattttaca
    27301 aaccaaagcg gcaatcgcga ggctgatttt atcaactgtg tgatttggcg caaatcagca
    27361 gaaactttag caaactatgc tcgtaaagga acacttttag gtgttactgg acgtatccaa
    27421 actcgttctt atgataatca gcaaggacaa cgtgtatacg tgacagaagt agtagctgac
    27481 aacttccaat tgctggaaag tcgttctgca tctgaaaatc gccaacaaag cggcggattc
    27541 caaagttctg gtcaatcagc tggcggattt ggcggaaaca ataactctaa tcaaacatct
    27601 caatcatcca acggtatgcc tgatttcgac cgtgatactt ctgacccatt cggctcaagt
    27661 tcaacgatcg acatttcaga cgatgattta ccattctaaa cgaatttgat aggagggaaa
    27721 tagaatggca caacaaagaa gaggcggacg taaacgtcgt aaagtagact acattgctgc
    27781 taaccatatt gaatatatcg attataaaga tatcgaatta ctaaaaagat ttatttcaga
    27841 acgcggtaaa atcttgccac gtcgtgtaac tggtacaggc gctaaaaacc aacgtaaaat
    27901 tactgttgca atcaaacgcg ctcgtatcat gggcttgcta cctttcgtta gcgaagacta
    27961 ataaatccta ggaattgaat gactgatcct tttgatcagc tattcaattc ctttttttct
    28021 gtaaaaataa cctctattcg tttagtcgct cgaatgacga aagttatggt aaaatcaaat
    28081 tagtcatata tgggaggaaa attatggaaa ataaaaacaa tcatttatcc ccgaaacctc
    28141 tcttccttat cctgtttata ttaatcgaag tattggtagt cttaatttta ccatttcgtt
    28201 ttgttagcgc ttcggtcatt ctattgatga atttatgggg tgttcgctat tggttgaaaa
    28261 tgaaacgttg gcttatttta aataaacgtg aaaaaatcca gcaggcttcg actgtagctg
    28321 aaaccaatct agcttatgtc tcagaagtca tgcctgtagg agtgattgct tatcagccat
    28381 caagccaaaa aatcgaatgg ctcaatccat tagcattgaa aatcaaagat caaagtggat
    28441 taacagagga agaattgcta gatacttttt ttactgcaaa agaaaaaaag aaaaaccaag
    28501 tctatctagc agataaaaca tttcagtttg atatggatac agtaaagggt gttgtttatt
    28561 ttaatgatat tacccaaaac cagttgttaa aactccatca gacgaacagt cagccggtga
    28621 ttggtatttt atctattgat aactatgcag atgccattga taaattggat gacaaagaga
    28681 tttcttattt gaactctttc gtcactacac tagtttctga ctggatgaat gaataccatg
    28741 tctttttcaa aagaatcaac gcagaacggt ttttcttcgt agcacagatg atcgatctga
    28801 aaaagatgat ggataaaaaa tttgatttgc tggatcgctt tcgagcagaa gctgaaaaac
    28861 agagctcgcc tatcaccctt agtatgggga ttgcttatgg ctcaagaacc ctcgatgaaa
    28921 tcggtggaga agctcagaat aatttagatg ttgctttagt ccgtggaggc gaccaagttg
    28981 tcgtgaaaga ggtaaaagaa ggagcaaaac ctgtttatta tggggggaaa tctgctaaga
    29041 atgtcaaacg cacgcgtgtt cgttctcgag cgatgagtac cgctttgcgt cggatttttg
    29101 atgaaacagg cgatgtgttt atcatggggc acaagtttcc ggatatggat gctttaggct
    29161 ctgcttttgg tgtcagttgt ctggcacgct tcaaccagaa aaaagcttac atcgttatca
    29221 acgagaacga gatcattcca gatgtagaac ggtgtcttga agaaatccat aagcatcctg
    29281 aattagaaat gcaactaatc tctccagaac gtgccataga gctgaaaaaa gaagaggacc
    29341 tcctcgtgat ggtggattac cataaacctt ctctatcgat ctctcagggc ctatatgagc
    29401 aatttgataa gattgtgatc attgatcacc atcgtcgtgg ggaagagttt ccaagtaaac
    29461 ctctgctgac ttatatcgaa tcttcagctt cttcagcttc agagctagtt tctgagctga
    29521 tccaatacca aagcagcaaa acaaatcgct tagatcgttt tgaggccaca ttattgcttg
    29581 cagggatggt tgtagataca aatagtttca atgtccgtac aactgcacga acttttgacg
    29641 ttgccagcta tttaaggtct tgtggagcag acgcatcctt agtacaatat ttattgagct
    29701 cggatttagc gacatacttg gagatcagca atttgattgc tggaagcgac tatgtgactt
    29761 ctgatattgt tgtggcggca gggacagacg aaaaagagta taatagtgtt atagcagcaa
    29821 aaacagcaga tacattgctt tcgatgatca atatcaatgc agctttcgtc attacaaagc
    29881 ggacagacgg cttgattggg atcagtgcca gaagtaccgg cacgatcaac gtccaaatca
    29941 tcatggaatc cttaggtggc ggaggacact tcacaaacgc agctactcaa ctggaaaata
    30001 cgacagttga ggaaacaaaa cagaagctat ttgctgcaat caaagaaaat atgaatcaaa
    30061 tatatgataa ggagtaatcc aaatgaaagt aattttttta caagatgtaa aaggaaaagg
    30121 taaaaaaggg gacatcaaag aagttccagc aggttatgca caaaattatc taatcaaaaa
    30181 taacttggca aaagaagcaa cgaaaagcag tatcagtcag ttagcaggac aaaagaaagc
    30241 acaagaaaaa cacgaagctg aaatcttgga agaagctaaa aagttaaaag aattcttgga
    30301 aaaagaagat actgtagtcg aattgaaggc gaaagcaggg gaagacagcc gtttgtttgg
    30361 ttcgatccct tcaaaacaaa ttgctgaagg gttaaacaaa caatacaaaa tcaaattaga
    30421 taaacgaaaa atcgaattag aaaatccgat ccgttcacta ggctacacaa acgtacctgt
    30481 taagcttcat catgaggtga cggctacgat caaagttcat gtcgtacaag aataacaaat
    30541 cttgatagcg atgttcagct ggtaagtata accagaagga aaaaagacaa accgaaattt
    30601 atctgagaaa acagctgcag caatgaaagc aaaagctgca aatcgatttc agattgattt
    30661 cggtttcttt tttgggaaca gcaaaatagc ataaagaaaa cgagtataat aaaagagaac
    30721 tattttttta ttacactttc ggtacgaatg atgacttttc tctcattttc ttgtaaaatg
    30781 aagcaattga agacaaggag cgatacgtat gaatgaagtg tggcaggatc gaatcccacc
    30841 gcaaaatatt gaagctgaac aagcggtttt aggctctgtt tttcttgacg cagaaacgat
    30901 cattgatgcc atggagtaca tagagccaaa agacttttat cgtcgtggcc atcaaattat
    30961 ttttgagaca atgatcgagt taaatgatcg taatgaagcg attgacgtgg ttactgtcaa
    31021 agaccggctg gaacaagcca atttgttaga agatgccggt ggtttaagtt atctctcaga
    31081 cttggcatta gcagttccga cagcagcaaa tatcgtctac tatgcgaaaa tcgttgaaga
    31141 aaaatcattg ctgcgtacat tgatccagac agcaacagga atcgttacga aaggattcga
    31201 gcaaggagaa gaagttcaaa caattttaga tgatgccgaa cgcagtatct tggaggtttc
    31261 ggaaaaaaga aatcgaagcg gctttttatc tattgctgaa gtactgaact ccacgattga
    31321 aaatatcgat cgactagctc aaaacaatga agaaatcaca ggtctaccaa ctggctatca
    31381 aggtctggat aaaatgacag caggtttcca gcccgaagaa ctaatcattc ttgctgcacg
    31441 tccagcggta ggtaaaacag cgtttgcatt gaatattgct caaaatgtag gaacaaaaac
    31501 agatcgttct gttgcgatat ttagtttgga aatgggggca gaatctcttg taaatcggat
    31561 gctttgtgca gaaggttcga ttgaggccag ccatttacgt acaggtcagc tttcggaaga
    31621 agaatggtcg aatctgatcg ttgcgatggg gagtctttct cgagcaaata tttttatcga
    31681 tgatacacca gggatcaaaa tctctgaaat ccgtgcgaaa tgtcggaaac tagcgcaaga
    31741 aaaaggcaat ctaggcttga tattgatcga ttatttgcag ttgattgaag gtaacggtaa
    31801 agagaaccgt caacaagaag tatcagatat ctctcgccaa ctgaaaaaac tggcgaaaga
    31861 gctgaaagta cctgtcattg ctctttcaca gttatctcgt ggagtagaac agcgacaaga
    31921 caaacgacca gtgctaagtg atattcgtga atccggatca attgaacaag atgcggacat
    31981 cgtagccttc ttgtatcgag atgattatta tgaaagagaa ggcggagatg acgatgatgg
    32041 aaacgagcca aaaaatgaca acgtcatcga agtcatcatc gagaagaacc gaagcggtgc
    32101 acgaggaaca gttgaactac tgtttatcaa agaatacaat aagttttcgt cgctttcgcc
    32161 aagagaagaa ttttaaagaa gaggttgtga gccttgagca atcccgagag ctctcgtaag
    32221 aagatgcaag gagtaaccgc aggaacgact agagtactta atttaaacag atctccaaag
    32281 ggattgtgac aaaagtcttg tcacagtccc tttttccgaa taaacggtgt tcaatcagct
    32341 gacccttggt attagctcag caaacgtcaa aatatgagga actattttga cgtttgtttc
    32401 tctaatactc aggtcaaaac gctgatctta cgacctcttt tccttaaacg gtgttctcct
    32461 gccaactcct cggtcacaag tcacaatatc atcaaacatg agaagcagtt ttttgaaatt
    32521 gctccttgtg actcagagtt aaacggcagg ctcacaacct ctttcttaaa cggtgttcaa
    32581 aagcttgcat ctgcggtaat acgcccaatc aaacgaaaaa tatgagaagc tatttttgtt
    32641 tggctgttct tattacttga tgcaggacag ctttttcaca acctctgatt cacggtgttc
    32701 caaaagtagc ttcttcgaaa aataagtcga aatttcacaa aaatttgaga agcaattttc
    32761 gtacattcct tcttatttct tgaagctgac cacttctgtt acaacctctt ttttaataac
    32821 cattctaaaa agataaagtt cgttttttaa gcgtttttat aaaataaaaa taaaaatcat
    32881 tcgattttat ttgaaatatg tatctattat tgatacaatg gttcaggatt aaataatata
    32941 gaacgaggtg ttcacatgtc atctgtagta gtagtaggta cgcaatgggg cgatgaaggg
    33001 aaaggaaaaa tcacagactt tctcagtgaa aatgctgaag tgattgcacg gtaccaaggt
    33061 ggcgacaatg cagggcacac aattaagttt aacggtgtga cttataaact gcatttgatt
    33121 ccttctggga ttttttataa agacaagatc agtgtgatcg gaaacggcgt tgtagtcaat
    33181 cctaaatcat tggttaaaga attagcttat ttacatgaaa aaggtgtaga aacaagtaat
    33241 ttgcgtattt ctgaccgcgc gcacgtaatc ttgccttatc atatcaaatt ggaccaatta
    33301 caagaagatg ctaagggcga aaataagatt ggtacaacga ttaaaggaat cggacctgcc
    33361 tatatggata aagcagctcg tgtaggtatc cgtattgcag acttattaga taaagaaatt
    33421 tttgaagaac gtcttcgttt gaatctagat gacaaaaacc gtcaatttgt aaaaatgttt
    33481 gattcagaac cacttgattt tgacgatatt tttgaagaat attatgaata cggacaacaa
    33541 atcaaacaat acgtcacaga tacttccgtt atcttgaatg atgctttgga tgcaggcaaa
    33601 cgcgtgttgt ttgaaggcgc acaaggtgta atgctggata tcgaccaggg aacttatcct
    33661 tttgttactt cttctaaccc agtagccggt ggggtaacaa tcggaagcgg tgtagggcct
    33721 tcaaaaatca ataaagttgt cggcgtctgc aaagcctata cgtcacgtgt cggtgatgga
    33781 ccatttccaa ctgaattatt tgatgaaaca ggagaacaaa tccgcgaagt aggacgagaa
    33841 tacggtacga caactggtcg tccgcgtcgt gtaggctggt ttgattctgt agttatgcgc
    33901 cattctaaac gagtttcagg tattaccaac ctatctttaa actcgatcga tgtattaagt
    33961 ggattggaaa cagtaaaaat ttgtacggct tatgaattag atggcgaact aatctaccac
    34021 tatccagcaa gcttgaaaga gttgaaccgc tgcaaaccaa tctatgaaga attgccaggc
    34081 tggtcagaag acattacagg atgcaaaaca cttgcagaac tgccagaaaa cgcacgtaac
    34141 tatgtacgtc gtatctcaga gcttgttggt gtacgtatct caacattttc tgtcggacct
    34201 gatagaacac aaacaaacat cttagaaagc gtctgggcgc aaatctaagg ataaaaacga
    34261 cgactgaatc aggacgttct taccagagcg agtcgaagtg tttatctata cgataataat
    34321 aacttgaaga ggtagtgaaa gagacgttta gccttattgc cgataggctg tctcttgaac
    34381 actgtttatt cagaataagg gactgtgaca aaaaccgtgt cacagtccct ttttccgaa
//
LOCUS       DAZUJR010000023        33959 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.023, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000023 DAZUJR010000000
VERSION     DAZUJR010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33959
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.023"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(27..1259)
                     /locus_tag="ACG804_001022"
     CDS             complement(27..1259)
                     /locus_tag="ACG804_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HFS4831969.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1514..2083
                     /locus_tag="ACG804_001023"
     CDS             1514..2083
                     /locus_tag="ACG804_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFS4831970.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2261..2701)
                     /locus_tag="ACG804_001024"
     CDS             complement(2261..2701)
                     /locus_tag="ACG804_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HFS4831971.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            2859..3623
                     /gene="map"
                     /locus_tag="ACG804_001025"
     CDS             2859..3623
                     /gene="map"
                     /locus_tag="ACG804_001025"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HFS4831972.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3655..4578
                     /locus_tag="ACG804_001026"
     CDS             3655..4578
                     /locus_tag="ACG804_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HFS4831973.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            complement(4803..5042)
                     /locus_tag="ACG804_001027"
     CDS             complement(4803..5042)
                     /locus_tag="ACG804_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4831974.1"
                     /translation="MSKDYGYPSFELICKASSGDEMAVKEILKFYDGYISKLCLRPFY
                     HSESGKIIMQVDEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(5047..5466)
                     /locus_tag="ACG804_001028"
     CDS             complement(5047..5466)
                     /locus_tag="ACG804_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HFS4831975.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
     gene            complement(5693..6931)
                     /gene="mef(H)"
                     /locus_tag="ACG804_001029"
                     /gene_synonym="mefH"
     CDS             complement(5693..6931)
                     /gene="mef(H)"
                     /locus_tag="ACG804_001029"
                     /gene_synonym="mefH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_070509550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide efflux MFS transporter Mef(H)"
                     /protein_id="HFS4831976.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSVSVLLMGISLFLELPAIVSYWVVTVMCFVAMGVSTM
                     FVVQIYTLVQTQTPPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVA
                     SIASIMISIYSKRIFQKLEI"
     gene            complement(7038..7673)
                     /locus_tag="ACG804_001030"
     CDS             complement(7038..7673)
                     /locus_tag="ACG804_001030"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFS4831977.1"
                     /translation="MARNKYPEETVKLILDVSTKMFCEKGYDNTSLQDIINETKLSKG
                     AIYHHFDSKEDILKAIFQRIGNENAVIFAKIRDNDSLNGLEKLREIFKTAVFNSNQSV
                     LLTVSPQLLNNPRFLAMQIEQMYEIVVPEFVEPVLEQGIKDKSLEIENSHEIAEVIMV
                     LSNVWLNPLVEMTDKEGMEKRCNTFNALLNGIGIDTLLDEETISAFIQFCK"
     gene            complement(7787..7879)
                     /locus_tag="ACG804_001031"
                     /pseudo
     CDS             complement(7787..7879)
                     /locus_tag="ACG804_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323349.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            complement(8015..8650)
                     /locus_tag="ACG804_001032"
     CDS             complement(8015..8650)
                     /locus_tag="ACG804_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4831978.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            9162..10304
                     /locus_tag="ACG804_001033"
     CDS             9162..10304
                     /locus_tag="ACG804_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFS4831979.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRFPTTDALEVIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGVIRRFDLAINDMCGLLDIPVLSEKYRNGGAECRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDKKAVQAVEELLLTYNPHG
                     LVFYLITDFVEFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDISDVIESEGVFYE"
     gene            10297..10503
                     /locus_tag="ACG804_001034"
     CDS             10297..10503
                     /locus_tag="ACG804_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HFS4831980.1"
                     /translation="MSNTQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEKVIDKLDAI"
     gene            10582..11775
                     /locus_tag="ACG804_001035"
     CDS             10582..11775
                     /locus_tag="ACG804_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4831981.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDGKYLYKYVDALGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRTNVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVIENDTKEKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQRVINSRPKIKSIEVDGHSGFVFINPKGNPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            11980..13119
                     /locus_tag="ACG804_001036"
     CDS             11980..13119
                     /locus_tag="ACG804_001036"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MraY family glycosyltransferase"
                     /protein_id="HFS4831982.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            13112..13912
                     /locus_tag="ACG804_001037"
     CDS             13112..13912
                     /locus_tag="ACG804_001037"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFS4831983.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            13912..14739
                     /locus_tag="ACG804_001038"
     CDS             13912..14739
                     /locus_tag="ACG804_001038"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFS4831984.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            14744..15451
                     /locus_tag="ACG804_001039"
     CDS             14744..15451
                     /locus_tag="ACG804_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFS4831985.1"
                     /translation="MRSVCIATFNGGRYLREQLDSILSQLSAEDEVVISDDGSVDDTW
                     DILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWLETKVKKITD
                     YFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYIGAGMAFRSS
                     LKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIETHSKLRQKIS
                     WRVHLITALIKRKWFKR"
     gene            15551..16417
                     /gene="rfbA"
                     /locus_tag="ACG804_001040"
     CDS             15551..16417
                     /gene="rfbA"
                     /locus_tag="ACG804_001040"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HFS4831986.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            16431..17003
                     /gene="rfbC"
                     /locus_tag="ACG804_001041"
     CDS             16431..17003
                     /gene="rfbC"
                     /locus_tag="ACG804_001041"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HFS4831987.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            17025..18053
                     /gene="rfbB"
                     /locus_tag="ACG804_001042"
     CDS             17025..18053
                     /gene="rfbB"
                     /locus_tag="ACG804_001042"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HFS4831988.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            18151..19002
                     /gene="rfbD"
                     /locus_tag="ACG804_001043"
     CDS             18151..19002
                     /gene="rfbD"
                     /locus_tag="ACG804_001043"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HFS4831989.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            19036..21069
                     /locus_tag="ACG804_001044"
     CDS             19036..21069
                     /locus_tag="ACG804_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4831990.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            21113..22393
                     /locus_tag="ACG804_001045"
     CDS             21113..22393
                     /locus_tag="ACG804_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HFS4831991.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFSVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNIIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQILLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            22603..23409
                     /locus_tag="ACG804_001046"
     CDS             22603..23409
                     /locus_tag="ACG804_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4831992.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            23421..24641
                     /locus_tag="ACG804_001047"
     CDS             23421..24641
                     /locus_tag="ACG804_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4831993.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            24631..26217
                     /locus_tag="ACG804_001048"
     CDS             24631..26217
                     /locus_tag="ACG804_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFS4831994.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            26256..28394
                     /locus_tag="ACG804_001049"
     CDS             26256..28394
                     /locus_tag="ACG804_001049"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFS4831995.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(28762..29745)
                     /locus_tag="ACG804_001050"
     CDS             complement(28762..29745)
                     /locus_tag="ACG804_001050"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFS4831996.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            30123..31514
                     /locus_tag="ACG804_001051"
     CDS             30123..31514
                     /locus_tag="ACG804_001051"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HFS4831997.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            31530..32570
                     /locus_tag="ACG804_001052"
     CDS             31530..32570
                     /locus_tag="ACG804_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFS4831998.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            32589..33674
                     /locus_tag="ACG804_001053"
     CDS             32589..33674
                     /locus_tag="ACG804_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HFS4831999.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            33707..>33959
                     /locus_tag="ACG804_001054"
     CDS             33707..>33959
                     /locus_tag="ACG804_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-1,6-N-acetylglucosaminyltransferase"
                     /protein_id="HFS4832000.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQN"
BASE COUNT        11003 a         5823 c         6696 g        10437 t
ORIGIN      
        1 ttttttgcat gtgtgcgaaa gtatactcaa gcccaatcgc catttcggaa aatcggtact
       61 gtagagccat cttcacggat tccgtcgata tccatcttgt cagatcctac catgaaatct
      121 acgtgggttt gacttctatt caatccagct tctgctaatt cttcatcgga catttctgta
      181 ccgcctttca cactgaaggc ataagcagaa cctagtgcta agtgattcga tgcgttttca
      241 tcaaataatg tattgaaaaa gatgatgcca gattgagaaa taggtgaagg gtcaggtaca
      301 agtgcgactt ctcctaaacg acgcgcacct tcatctgtat caagcagttt tgctaagaca
      361 tcttctcctt gttcggcaga aaaatcaaca acttttccat ctttaaaagt aaatttcata
      421 cccgagatga tggtgccagc ataactcagt ggctttgtac ttgaaatgta accatctact
      481 cgatgactgt caggtgctgt gaacacttct tccgtcggca tatttgccat gaatttttct
      541 ccacgagcat tatagcttcc agcgccttcc caaagatggt ttttaggcaa tccgataatg
      601 atatctgtac cgggagcagt atagtgaagg gcagaaaatt gttctcgatt caattcttct
      661 gctttttttg ctaatttttc atcatgcttc ttccatgcta agacagggtc ttcttcatag
      721 acacgagtcg ttttgaaaat ctgatcccat aatgcctcaa cttgtttttc ttctggcagt
      781 tctgggaaga cttttgctgc ccattgttta ccagccgcag ccacgacagt ccaactgact
      841 ttatttgctt gagttgcctt gcgtaaattc attagtgctt tgccattcgc tgattgataa
      901 gacgctactc gatggctatc tacaccagca aatgcatcgg gatcggcaga aacaacgctg
      961 atcctgcttg ctcctttttc aagccattca tccgcttgat cgattttaga ttgtggtaca
     1021 ttctcaatac gatccgttgc agcatgtaaa agaaattctc tttggatctg gtcgtcagtc
     1081 cattgaacga taacctcagc ggctcctagt ttataagctt cttgtgtgat caatcgagca
     1141 aggggtgcct gttccacgct gatctgtaaa acaactgtgt gtcctttttc tgtggctacg
     1201 ccagtttctg caattaagcg tgcatatttt tttagaagtt cattaaaatc agataacata
     1261 ataaaaattc ctcctcacca ttttttctgg taactattag catgatacca tttaattatg
     1321 attcaaacaa tgaggcttta aataaaaaaa ggaggttatt tttttaaggt taagtttcat
     1381 gatatatgtt actacttgct atttcagctt gtgaagaaaa tcaaaaacta attttgcata
     1441 tcaaaaaaaa catgttacaa tgaaattaat caatggtgga agcgttataa aaaaattaag
     1501 gagattaaaa aatatggcaa gaaaaaagac gattactaga gaacagattt tggcagctgc
     1561 ttatgaagta gctgccaccg atggatttac acgatttact gcgagaaaca tcgcgaacaa
     1621 aatgaattgt tccacgcaac cgatttatct tgagtttaaa aatatggatg acttgagaca
     1681 agctcttttt gagcagatct atgatcattt acaatatgaa gtgttcactg ttgagcatac
     1741 agggaatacg attatcgatc ttgcttttaa ttatatccat tttgcaagaa gagagaagaa
     1801 gttgtatcgt tcactgtact tagaagaata tggtggagga aaagagatgc agaatttctc
     1861 ttatacttac tttgtgaata cagtgaaacg cgatccagct tatgtgaatc tttcagaaga
     1921 gcagatcgaa tctttgtata atgggacatg gatcatagct actgggatcg cagctttgat
     1981 gtcttcaagc atcatccatc caactgatga acagattgaa aagatgatcc aagacagtat
     2041 agatgctatc ttgaaattca aagaaccaat cgaaatcgat tgaatatact caaaagttcc
     2101 acaaatcagt aggtaacaag agatgtgtca aaataaggaa aagttcgttt ttcttacagc
     2161 gtatgcattt ttaactcccg aagaactctt ccatgaatgc aatgaataaa agagccatac
     2221 agattgaata aatctggatg gctcttttat tgcaagtata ttaaattttt gcgactagtt
     2281 ctttagcgaa agcttctaaa ttttcgatat cttcttcttc agcattcaga tccactttaa
     2341 cattttcggc tccttttgat gcgcctgttt ttgcaaaagc agcatcgaaa tcatccaccg
     2401 atttgcagaa ttcatcgtaa aaagtatcac cagatccgca gacaccgtaa atttttccca
     2461 atagatccaa ttcttgcaag tcttcataaa agtctacgat ctcatcaggc agatcgccat
     2521 catcgtatgt ataagtagct actacgcaaa tatctgcctc ctcgaattca tctgcatcta
     2581 cttgggtaca ttcgttgatt tcgacttcga tatccagatt ttcaaatgct tctgcaacaa
     2641 tatcggcgat ttcttcagtg tttcctgtca tgctagcata tacgattttt gctaaagcca
     2701 tgatgtgcct cctcgtttat aattatttaa caattatgaa ttataccaaa acatcattga
     2761 aaagaaaata aaacctagag acacctgggg aatgtcattt ggctaaatgt atgccgctat
     2821 gttaaaatga gagggatttg taaaaaggag acgaaaatat gattacttta aaatcagcac
     2881 gtgaaattga aatgatggca gaatctggag ctttattagc agatgtacat aaaaatctgc
     2941 gtgattttat aaaaccagga atcacaagtt gggatattga ggtatttgtc agaaactata
     3001 tcgagagtca tggcggaatt gctgcgcaaa ttggctttga agggtatgaa tatgcgactt
     3061 gtatcagtat aaatgatgaa atttgtcatg gattccctcg taaaaagcct ttgaaaaacg
     3121 gtgatttggt aaaagtcgat atgtgtatcg atttgaaagg cggcatttct gattcttgtt
     3181 gggcctatgt agttggagaa tctacacctg agatcgaccg attgatggaa gtaacgaaga
     3241 aagctttgta catcggtatt gagcaagcac aagtagggaa tcggattggt gacatcggtc
     3301 atgctatcca aacttatgta gaaggcgaaa atctagcgat cgttcgtgat tttattggtc
     3361 atggcgttgg tcctacgatt catgaagaac cagcagttcc tcattacgga gaagctggaa
     3421 aagggttgcg gttgaaagaa ggcatggtta tcacgatcga acctatggtt aataccggaa
     3481 cttggaaaat gaaaatggat cctaacggct ggactgcgta tacaagagac ggcggacttt
     3541 cttgccaata tgaacataca ttggctatta ctaaagatgg tccaagaatt ttgacatcac
     3601 aaggagaaga aggcacttat tgatctatcc agtcaatagg tacgggagag gtacatgaaa
     3661 gtttggaaca aaataaaaca aaatgaaaat ctgatgcgct ttattgagac gactcaaaag
     3721 cgcatcactg attcagaaat gagtacgacc tctgtcgtcg ttgcttatta tttactcttg
     3781 tctttatttc cattgattat tgcttttggt aatattttac cgtttctcca catcgatcaa
     3841 gagactgtac tgacctattt acgagaagtg attcctgaga ccgtttacca gtttatcggt
     3901 cctgcaatca aagacctttt gacacaaagt tcaggaggct tgttatccgt ttctgcatta
     3961 gcggctttat ggtctgcaag tcaaagtatc aatgctttgc aaattgcgat gaataaagcg
     4021 tatggcgtag aaaatagaaa aaattttttg atcgtccgtt tcttctcact aattgtcatt
     4081 gtcttgttca tgattgctat tagtggggta actatcgttc ttgggttggg acagctgatt
     4141 ttggatgcta ttcagccaat cgtacaaata cccgtgaact ttatcgatca gttccaaact
     4201 ttgaagtggc caatcacatt ggtagcttta tttgtcatca tgttcttgat ttatttaatt
     4261 gtccctaatg ctcagttgaa gttgaagacg atcattccgg gcacgatctt cgctactgtc
     4321 ggctggatgc tgttatcaca agtgtttagt atctatgcta ggtattttgc aacgaggatc
     4381 agcggttatc agatcatagg aagttttatt gtactcatgc tttggcttaa ttttgctgct
     4441 acgatcatca ttttgggcgg aatcatcaat gcagttgttc aagaatacgt gacgggtcat
     4501 caaatcaaaa aacgtcgaga tccaagccga aaatggttca ataaattgaa aactaaattt
     4561 tctcataaaa aaaagtagaa acaagagttc ttattgtaaa tttatatcag taatttattt
     4621 gaaattttat atctaatttt caattatccg cataaacact atacattcaa gcattttgaa
     4681 gtatagaaaa acactcatct taccacgaat ttaccacgat tgaatgagcc ttgatatgac
     4741 cgtaaaacta ctaagggaga tagcacgaaa ctgtgtatct cccgattttt ttatacagtt
     4801 gattacttca ctccgatttc aaatttcaat attgctttca tcatgtctgt atgaatttct
     4861 ccttttagtt cttcatcaac ctgcataatg attttaccac tttcagagtg gtaaaaagga
     4921 cgcaagcata atttagaaat ataaccgtca taaaacttca aaatctcttt aactgccatt
     4981 tcatctccgc ttgacgcttt gcaaatcaat tcaaaagagg gatagccata atctttactc
     5041 atttctttac ttcctttcgc tcaaaagcat ttttaacttc cttagtcctc tagttcttct
     5101 actgcaaata gcagaacgtg atacatggta cagttctgaa atttctctgt cgttcattcc
     5161 ttgaaaataa cgtaataaaa tcgcactacg ctgtttttct gacagtctat gtaaaactgt
     5221 accaagtgtt tcatcagata cataaattgt aaagtgcaag actttaaatg atacacaatc
     5281 ataaaaacag gtatcaatcg ttccacgttc aacttgtttc gtttcggcta tttcacaaaa
     5341 caatacttca cgtttagaat gtcttgcaag ctgtctgttt cgacttttca ctttgttctt
     5401 aatgacaatc agcattaaag aattgaactg taatctgacg atatgctcga aagaagatgt
     5461 cctcataatc tcaccccctt tctgctaatg ctgaaatata taaacggaat accgtttata
     5521 ccctttagaa atacagaaaa atggtaagaa aaaagcccac acaaaacata tatttgtgcg
     5581 agccttaaat actgcaatat tactctttct tttataacac tatcctttta gcagatttca
     5641 aattttcttt tatatattgt ttttagccta acatactatt taaccccttg tattatatct
     5701 ctaacttttg aaaaattctt tttgaatata ttgaaatcat gattgaagca atagaagcta
     5761 caaacataac aacccatgtt tcttgtataa atacatcgaa taaaataccg taaaccattt
     5821 gtccaatagg ttgaccgcac atagcaactg ctaccagcgt agccattatc tttcctacta
     5881 attgcggtgg tgtttgtgtc tgaacaagag tgtaaatttg aacaacaaac atagtagata
     5941 cacccatagc cacaaagcac atcactgtaa ctacccagta ggaaactatt gcaggcaatt
     6001 ctaaaaatag cgaaattccc ataagtaaaa cagaaacaga acaaataagt aacaaggtat
     6061 aaaggttttt tagttttaac tttgaagcaa caagagctgt taaaatacca ccacataaac
     6121 cacctaatga taatgctgat tgtgaaaaac catatagtgt atctggcatt tttaaaactt
     6181 cagaaattaa gataggcaga ccaacaatta aaacagcact taaaaccaaa ttgaaaatgc
     6241 aaaccaaaaa gattacggat ataaaaatgg gtttctcctt tttcaaaaag gtataactat
     6301 cttttaaatc gtttttagca actgcaatta cacctacttc acgaggtctt ttttggtgtg
     6361 gaatatggat aaaaatttcc ataatggctg aaaaagtaaa acatataata ctaacaatta
     6421 aaatgggatt gataccataa aattgaaaaa ctactccgct tatagctggt ccgataaagt
     6481 ttgctaaagt atttacttga tttattatag cattaccgac ggtaagttta tctgatgata
     6541 ccaatagagg aatacttgct tgtaccgctg gttgatatgc accagaaata ccataaagta
     6601 acatcaaagc aacaataaac aaaggtatga taggaatttt tcccaatgac aaataaaata
     6661 ctaaaattat gattgctgtt acaaaatcta gtatgaccat aatgtttctt ttatttgtcc
     6721 tgtcagcaat aataccacct accagcgaca aaataaccat aggtaaaaaa gagcaggctg
     6781 tagcaatacc aaacaaagct gatgaaccag tttcttttaa caaatagtac ggtaatgcaa
     6841 atcgtaggat agcgtttcca aataaagaaa ttatctgtcc tataacaaca agtataaaat
     6901 cacgattaaa aagttttttt tctgcttgca taaaatctct cctttttatt taatcaaaca
     6961 gaccgtcggt ttatataatg gtttaaataa actgctcttt tatagagcag tctatcgtat
     7021 agggataaca aatacagtta tttacaaaac tgtataaatg cagaaattgt ttcttcgtct
     7081 aataatgtgt ctatgcctat tccatttaaa agggcattga atgtattgca acgtttttcc
     7141 ataccctctt tatccgtcat ttcaactaat gggttgagcc atacattact taataccatg
     7201 ataacttctg caatttcatg tgaattttca atctccaaag acttatcctt gataccttgt
     7261 tctaaaacgg gttcaacaaa ttcaggtact acaatttcat acatttgttc tatttgcata
     7321 gcaagaaaac gaggattgtt taatagttga ggagaaactg tcaataaaac gctttggtta
     7381 gaattgaata ccgctgtctt aaatatttct cttaactttt ctaaaccgtt taaactatcg
     7441 ttatctctaa ttttagcaaa tattactgca ttttcatttc caattctttg aaaaattgct
     7501 tttaaaatat cttcctttga atcgaaatga tgataaatag cacctttaga aagttttgtt
     7561 tcattgataa tatcttgcaa tgatgtgtta tcatatcctt tttcacaaaa catttttgta
     7621 gaaacatcta aaatgagttt tactgtttct tctggatatt tatttcgtgc cataacttac
     7681 ctccaataca aaccgttggt ctgattaaag tatatcttag tattttatgc ttgtcaatat
     7741 aaagacttgc aattttataa aaatgcagaa tgcaagcctt tttcatttat tctacaatct
     7801 tccagttgct ttccttatgc ggtgtcaatt catactgtga tacctgcgtt gcctttgcct
     7861 gatttaccac aaatcagatt ttatcccttt cttcctcttg attgcccaca acagaaaaga
     7921 aaaagccctg tcaagagctt tgccaccatt ggtggtgctt tgcactcttg atcgggcttt
     7981 ttgtttgctg tatcttctcg caagaggaaa aaagttactc gtcctcatca tcaaaattgt
     8041 tattccttaa tacttctcgt aacagttcca tatcttcttt tgagttcggg tttatcattt
     8101 tcacgacttg ataaggtgtc ttatacttat gtccctctat gctttcccca aacatatcca
     8161 tactgtataa atcatcatag cggtctaata atttttgaaa cttcaaatgc tggataaatt
     8221 ctttgattgg gtaaaggtcg gacgcttcaa tgcttttccc gttgatatag tctgtaatat
     8281 attcccgtaa cttttctaac tcatattcca gccattcttc ctcgctgtca aagaagttat
     8341 catagtgtcc atgtttcagt tctgcattta gacgttcttc ggctcttaaa aactgacaga
     8401 cttccttttc agattgattg acatacttcc attctcccga caacaattca ttgggcgtaa
     8461 cgtccagcac ttccattatc ttttccagcg tttcataggc aggatagttc aaccctcttt
     8521 caatcttgga aaggctctgc atattgatac cgattttgtc cgcaagttcc tgttgtttca
     8581 ttcccctaaa ttttcttatg gtctgtatat tatttcctaa atggcttatt ttcattgcat
     8641 aaccctccat atctcgttat atcttcgcta ttataagtct atcatgctta atatgatttg
     8701 taaaggcaaa aaaagatatt gacaaataag catataagaa ttactatgtt cttgtaatcg
     8761 aataagcaca atagaatgaa atataaaaac attcaaaaag aaatacctat ctgattaaat
     8821 ccgtagatat gaatatcggt tgaaatggaa cttgttagaa aaggcaaaac agaacttgct
     8881 gacaaagtat ttctgacacg gtggcggaag cctctcaggc ttaccgccat gacaccttgt
     8941 gtcaagggga agaaatgctt tgtcggctgg cgagcctgcg agccttgtct gtgcccccgt
     9001 tatctaacag gggggcacta tttcacaaaa gacaagtcaa aaaccataca cccccaaacc
     9061 tgtgagtagt aatgagaggt tttaagaaga tagtacatat cacacttttt gaaaggtggt
     9121 ttacaggtat ttcaaggcta ttgtgggatt ggaggaatac aatgaacaat ttagaatttg
     9181 cacttgaaat gaagaacaaa cgtcttgcca gcggtctttc acaaggagaa cttgcaagtc
     9241 ttacccatgt atcaagatat agtatcaacc gctttgagaa cggaaaagct aacgccagca
     9301 aggaaacaca gaacattatc ctgcgttgtc tgaattacta tatctgcgat aagccttttt
     9361 atctgctcgt tgattatctg tctgtccgtt ttccaacgac tgacgcattg gaagttatcc
     9421 gaaaggtgct tggcatgaaa gcagattatt ttatccatta tgactatggg tattatggct
     9481 ataaggagca ttatgcttac ggggaaatca aggtcatggc ttctgatgat gaacacatgg
     9541 gcgtattttt agaattaaaa ggggcaggct cacgcaacat ggaatatgtc ttacaggcac
     9601 agaacaggga ctggtattca ttcttaaacc gctgtcttga ctgtggcggt gttatccgac
     9661 gttttgactt ggcaatcaat gatatgtgcg gtctgctgga tattcctgtg ctatctgaaa
     9721 aatacagaaa tggtggtgcg gaatgtcgct gtaaaaacta tgaaaatgta caaggtggaa
     9781 aattaagcgg aaaaaaccgt aatttagcaa gtacccttta tatcggctca aaggcaagca
     9841 caaaatattt ctgcctgtat gaaaaacaaa aggaacaggc aacgaaaaag aaacataccg
     9901 atattatcaa ccgttttgaa attcgtctgc gtgacaaaaa ggcggtacag gcagttgaag
     9961 aactgttatt gacgtataac cctcatgggc tggtgtttta tctcattacc gattttgtgg
    10021 aatttcctga ctatccattg tgggagatat tcatttccca tgacagttta ccttttgaaa
    10081 tgaaccctgt acctgtcaat atggaacgca ctctgcaatg gctggaaaga caggtcatgc
    10141 cgtcaatcgt gatgatagag gaaatcgaca ggctgacagg ttcaaactac atgaaaatga
    10201 ttgatgaatg tacccacctt tctgaaaaac aggaaatgct tgtggaacag atgtgtacgg
    10261 acatatcaga cgtaatcgaa agtgaggggg tgttttatga gtaatacaca ggatattccc
    10321 gtatgggaaa aatacaccct taccattgaa gaagcgtcaa agtatttccg cattggagaa
    10381 aacaagttaa gacgattggc agaggaaaac aaggacgctg gctggctcat tatgaatggc
    10441 aaccgcatac agattaaacg ccgacagttt gaaaaggtta ttgataaatt ggacgcaatc
    10501 taatgcaaat gagccttgta tgtgttatga tgaacacaag tcatatcaag gctctttcca
    10561 acaaggaaag gagcagacac catgaaagaa aaaagacggg ataacaaagg tcgtatcctg
    10621 catactggag agagccaacg aacagacgga aaatacttat ataaatatgt agacgcattg
    10681 ggaaacacaa aatatgtgta tgcttggaga ttgacaccca cagacccgac accaaaggga
    10741 aaacgggaaa aaccctcact tcgagaactg gaacagcaga taagacggga tattgaggac
    10801 ggtatcgaca gcacaggcaa gaaaatgacg ctttgccaac tctatgccaa acagaacgca
    10861 cagaggacaa atgtgaagaa aagcacacag aaacaacggg aacaactcat gcggttatta
    10921 aaagaggaca agttaggtgc taggagcatt gatacgataa aaccctctga cgctaaagaa
    10981 tgggcgttac gcatgaaaga caaaggcttt tcctacaata ccattaacaa ccataaacgc
    11041 tcgttaaaag cgtcattcta catagccata caagatgatt atgtgaggaa aaaccctttt
    11101 gatttcaagc taagtgaagt catagaaaat gataccaaag agaaagtcgc attgacagag
    11161 gaacaggagc aagccttatt gtcatttatt aagacggaca acgtgtatca caagcattat
    11221 gatgatgtgc tgatactgtt aaagacagga cttcgtatct cggaactgtg cggactgaca
    11281 gtagccgaca ttgatttcaa gaatgaagtt gtgattatcg accaccagtt actaaagagt
    11341 aaggaacagg gctattatat tgaaacgcct aagacgaaaa gcgggataag gcaagtgcca
    11401 ttaagcaaag aaacgataca ggcatttcaa cgggttatca acagccgacc aaagataaag
    11461 tcgatagagg tagacggaca cagcggtttt gtgtttatca atccgaaagg taatccaaaa
    11521 gttgccattg attataacgc cttatttatc cgtatggtaa agaaatacaa caagcaccac
    11581 aaggacaatc ccttgccaca tattacaccg catacgctac gccatacatt ctgcacaagg
    11641 ctggcaagca agaacatgaa cccgaaagat ttacagtata tcatggggca ttcaaacatc
    11701 agtatcacaa tgaactggta cgctcatgcg tccatagata ccgcaaaatc agaggttcag
    11761 cgtctaatcg catagaagta tttaccacga ttttaaccac gattgacagg gaaaatataa
    11821 gaagatagac ctagatatgc gaggtttacc acaaaagcaa aatgcccgta gagccgataa
    11881 aataaggctt tgcggacatt tgagaagata taaaaagata gtcaaaaaga catatataat
    11941 ttataataat tatgactctt aattaaagta ggtgcccata tgcttgtttc ttttagtatg
    12001 gttataagat tttttctgac aattttatta tcactgatat taacacctgt attcaaaatc
    12061 atttcagtac aaacaggtat ggtcgacaaa ccaaatgaaa gaagaataaa taaagttcca
    12121 atgccttcag cgggcggact gcctatcttt atttcatttg ttatatcgac tttattctta
    12181 ttccgtaaaa ttatccctca atcgtatatt gtaccgatct tgattgcttc tttagtaatc
    12241 atagtcacag gagtgctcga tgataaatat gagctgacac ctaaacaaaa aagtataggg
    12301 atcttgattg cttctcttat tatttatttt gtagcagata tacgtattga ttccttcacg
    12361 cttcctttta ttggatatat ccaactaggc tggcttagtt ttcccgtaac gattttttgg
    12421 atcttcggta tcacgaatgc ggtcaatctg attgacggtt tggatgggct ggcggcaggg
    12481 atttcattga tcggtttaat tacgatagga atcattggat attttttcct ccatgcttct
    12541 acagtgtata ttccagttgt tattttctgt cttgtagcaa gtattatcgg tttttttcct
    12601 tacaattttt atccggcaaa gatttattta ggcgatacag gagctctatt cctagggttt
    12661 atgatggccg tcctttcact acaagggctg aagaacgtga cttttgtttc atcgatttct
    12721 ttgctgatcg tcatgggagt gccggtaaca gacacgtttt ttgctatcat taggagaaaa
    12781 gcaaaccgtg tttctttttc tacagcagat aaaaaacatc ttcatcaccg actaatcagt
    12841 ttaggcttta ctcataaagg tgctgtcctg acgatttatg cgatggcttt gatgttttct
    12901 ttcacagcta tggtcatgaa ttatactgga agaatcggaa cgatcatatt gattattgcc
    12961 atgttgtttg ctgcaatttt attatttgaa ttgattggtc tgatcaatga gaaacatcag
    13021 tttattttaa aaacattgcg atttttaggg aataaagagt accgtacgca agtaaaacag
    13081 aaatatttga agaaatggaa ccgtcatata gatgaataac aaattaaacc agccgatcct
    13141 tattagtatt gtgacggcaa acagtgataa aatttttcgg acactagata attttatttc
    13201 aactgtaaaa gatgaaacag cagtaaaaat ccgaattttt gacaacaatt cacttcccga
    13261 gtacaaaaaa agactaacag agtataggaa atatccctac atcgatatct attttcatga
    13321 tgaaaattcc ggatttggtt atggacataa tcacaatctg atagctagcg attctcgcta
    13381 tggcattatt tgtaacccag atattttagt ggatgaagag acagttacag cattggtctt
    13441 gttattgaaa gaacatccgg aatgtgcgat gttagcacct aagattctta atgaagatgg
    13501 aacaactcag cacctcatcc gtgagcagct ggctgttttt gattacgttt tgcgctttgt
    13561 gcctttcaaa tgggtcaaaa aaaagtttga caaacgactg gctgtgtttg aatgccgagg
    13621 attgcctact gatgctaata gttatgtacg gatgatctca ggtagtttta tggtagctga
    13681 tattgataaa tttaaagaga taaaggggtt tgatgagcgt ttcttcatgt actttgaaga
    13741 caacgacttg tgtttgagtt ttgaaaaagc aggttacaag ttattgtaca caccctttta
    13801 tgcagttatc catttttacg ggaagggtgc gcatcgaaat gcaaaactgt ttcgcgtgtt
    13861 tttgacttct atgatgaaat ttttcaataa gtgggggtgg cgttttttct gatgaaacca
    13921 gaaatattag tagtcgttgt gctttatcag caactattca gtcaatctcc agcttatgga
    13981 ccattaagca aagcacttag cgaaaagcaa attcagctta ttatttacga taatagtcct
    14041 caaaggcagc aaaatgagct gtttgaaaaa gaaaatatcg tttatcatca tgatccgcaa
    14101 aatcctggtt tagcggtggc ttataatttt gcgttgtctc aagcagatga aggaacacgt
    14161 tgtctcgtca ctctggatca ggatacgagg ctagtcgacg attattttga actattgcgt
    14221 aaagtaacct ttacagatga atgtgttgct gcagttccga tgattttttc tgggagccga
    14281 caagtttctc ccctatattc agatcgttat atcaatcgta cagctcaagc agtagaagtt
    14341 gaaggcccaa cagctgaacg aatcatggca atcaattcag gtgttgcctg gtctgtcaaa
    14401 tttctaaaaa agattggcgg gtttaatcct gctttttctt tagatttttt ggatcattgg
    14461 ctgttttgga aagtggatca gttggaaaaa actgtggaga tccttcctgt acgaatggaa
    14521 catgatcttt cggttttaga ctatgaaaaa gtttcaagta atcgataccg ttctatttta
    14581 caagcagaaa atcgatttta tcatgaatat gatcaaaggc atttatccag tcaccgacga
    14641 caattattgt taagaacagc taaacagttc ttgaccgtca aaaaccggca tatctggcgg
    14701 atgactttgc gctcatatgt taagaattgg aaggtgtgaa ttcgtgcgtt cggtttgtat
    14761 agctaccttt aatggaggca gatatttaag agagcagtta gatagtattt tatctcagct
    14821 ttcagcagaa gatgaagtag tcatttctga tgatgggtca gtagatgata catgggatat
    14881 attaactgaa tacgcagaaa aagataagcg aatccagctt ttttcggggc ctcgtcaagg
    14941 attgatcgct aattttggtt atgcgatcca gcagacgaaa ggagatctaa tctttttggc
    15001 agaccaagat gatgtttggt tggagacaaa agtgaaaaag atcactgact attttgagca
    15061 gaatccggat cagctagtag tagtttctga tttaatcatt gtggacagcg agctgcaaga
    15121 gatccatgat tcgtattttt cgtttcgaaa ttccaaagaa ggatggctta ataatgtgat
    15181 aagaagtcac tatattggtg ctggtatggc tttccggtct tctttaaaac ccgatatttt
    15241 gccgatcccg tcagaagtgc cgatgcatga tatgtggatt ggtttgctgg gaggaaagaa
    15301 gactgggttc ctaagagaac cgttaactct gtaccgaaga catgatttaa acgcgagtga
    15361 gattgaaaca cattctaaat tacggcaaaa aatttcttgg cgtgttcatc tgattacggc
    15421 gttgatcaaa cgaaaatggt ttaaacgttg ataaaagatg tttaaatcct taatatttcc
    15481 atgacaaata taacaattga tgagataata acaaagtgaa atttgaaatc aaaaaggaga
    15541 gcagatatcc atgaagggaa tcattcttgc tgggggcagc ggaacacgtc tgtacccttt
    15601 aacaaaggca acatcgaaac aattgatgcc gatttatgac aaaccaatga tttattatcc
    15661 aatgtctact ctgatgttgg cgggaatcaa agaaattctg attatttcaa cgccacaaga
    15721 tacaccacgt ttcaaggaat tatttggaaa cggaaatgat ttaggactgc agatcgaata
    15781 tgcagtacaa gaaagtccag atggattggc acaagcgttt atcattggag aagaatttat
    15841 tggagatgat agtgtctgct tggtattagg ggacaatatt tactatggtg gcggtctgtc
    15901 taaaatgttg caacgagcag cttcaaaaga tacaggcgcg acagtatttg gctatcatgt
    15961 caatgatcca gaacgctttg gtgtagtaga atttgatgag aatatgcaag ctttgtcgat
    16021 tgaagaaaag cctgctcagc caaaatcaaa ttacgctgta actggccttt atttttatga
    16081 caatgaggta atttctatcg ctaaaggtat caaaccttca gaacgtggag aactagagat
    16141 tacggatgtc aataaagcat atttggataa aggaaaacta tccgtagaac ttatgggacg
    16201 cggatttgct tggcttgata caggaacaca tgaatcattg cttgaagcat ctacctttat
    16261 cgaaacaatt gaaaaacgtc agaacttaaa agtggcttgt ttggaagaaa ttgcttaccg
    16321 tatgggctac atcgataagg aacaattgct ggcccttgca cagccattga aaaaaaatca
    16381 atacggtcaa tatttattga atttggccgc tgaataagga gtccttacag atgaaagtaa
    16441 cagatacaaa attaacagat gtcaaaatcg tagaaatgga cgtctttggc gatcatcgcg
    16501 gtttcttcac agaaagttat tcaaaagcaa aatttgcaga acatggattg aaatatgact
    16561 ttgttcaaga caaccattca ctatcagctg aagctggtgt ccttcggggg cttcatttcc
    16621 aaaaaggaga agctgcacag acaaaattga ttcgggtagt cactggagca gttttagatg
    16681 tagtagtgga tatccgcaaa ggtagcccga cttatggtca atgggacgga tttatcttat
    16741 ctgaacataa tcatcgacag ttgcttgtac ctaaaggata tgcccatgga ttcgttactt
    16801 tgacaccaaa tgtgaacttc ctttataagt gtgataatta ctataatgca gaagcagatg
    16861 ggggcatcgc atttgatgat ccagatttag cgattgattg gccaattgat ccatcaagag
    16921 cgattatgtc ggaaaaagat caccgtcatc cgacattaaa agaatttgaa gcagaaaatc
    16981 catttgttta cggagaaatc taagaattaa ggagaaattt tcttatgaaa aacatcattg
    17041 ttaccggagg tgccggattc atcggctcta atttcgttca ttacgtggta aacaatcatc
    17101 cagaagtgca tgtcactgtt ttggataaac tgacttatgc aggaaacaaa gagaacttgg
    17161 ctggacttcc tagcgatcgc gtagaattgg tcgtaggaga tgttgcagat gcagaattag
    17221 tggaccgtct agtaaaagaa gcggacgcag ttgttcatta cgcggcagaa tcccataacg
    17281 ataattcatt aaaagatcct ttcccatttg tacaaacgaa tatcattggt acgtatacac
    17341 ttttagaagc ttgccgcaag tatgatgtac gctatcatca cgtatctact gacgaggttt
    17401 acggcgatct tccattacgt gaagacctgc caggacatgg ggaaggcgaa ggagaaaaat
    17461 tcactgcgga aacaccatat aatccttcaa gtccatattc ttctacaaaa gctggttcag
    17521 atctgttagt aaaagcatgg gtgcgttctt ttggcttacg tgcaaccatt tcaaactgtt
    17581 caaacaacta tggtccttat cagcatattg aaaaatttat tcctcgccaa gtaacgaata
    17641 tcttaagcgg tattcgtcca aaattatatg gcgaaggaaa gaatgttcgt gactggatcc
    17701 atacgaatga tcattcttca gcagtgtggc tgattttgac gaaaggcaga attggcgaaa
    17761 cctatctgat cggtgcagac ggtgaagaag ataataagac cgtgatggaa ttgatcttag
    17821 aaatgatggg tcaaccaaaa gatgcgtacg accatgtaaa cgaccgtgca ggacacgact
    17881 tgcgttatgc aatcgattcg acaaaattac gggaagagtt aggatggaag cctgagttta
    17941 cgaacttccg tgatgggttg gctgacacga tcaaatggta cgaagaacat gaagactggt
    18001 ggaaaaaaga aaaagaggcc gttgaagcag catatgccaa aaatggacaa taatacagag
    18061 aaaatgtcac tgtattaatg gaaaaacaca tgtgaggcag gcgctcgcct gtctcttttt
    18121 taaaataaaa atcaaggagc ggataatcat atgtttttat taactggagg aaatgggcaa
    18181 ctaggtacag aattgcgcca tttattagat gaaaaaaatc tgcaatatgt ttcaacagat
    18241 gcaaaagact tggatatcac agatgccgag aaaacaatgg cttacatcac agaattaaaa
    18301 cctgatgtta ttttccattg tgcagcttac acagcagtag ataaagcaga agaagaagca
    18361 aaagaattag atgagaagat caatgttgat ggtacaagaa atgtagcact tgcagcaaaa
    18421 gctgtgaatg ctcaattcgt ctatatcagt acagactatg ttttcgatgg aaaaaacaaa
    18481 aatgtagaat acgaagtaga cgaccaaacg aatccactaa atgaatatgg tcgtacgaaa
    18541 ttattaggcg aaaaagcagt agaagagatt ttagaagact attatatcat acgaacttct
    18601 tgggttttcg ggatctatgg acacaatttc gtcttcacga tgcaacgcct agcggaaacc
    18661 cgcgacaaac tgactgtagt aaatgaccag tttgggcgac caacttggac acgtactttg
    18721 gcagaattta tggtatatgt catcgaagaa aaagcaccat ttggtattta tcatttgtcg
    18781 aacgaaaata gctgttcttg gtatgaattc gcaaaagaaa tattgaaaga tacagatgta
    18841 gaagttgcac ctgttacgtc agaagaattt ccgcaaaaag caacacgtcc gcagtattca
    18901 gtcatgagcc tgaaaaagac agaagagtta ggatttgtca taccaacttg gcaagaagca
    18961 cttgcgcaaa tgctggaagc tgccaaaaaa atgaataagt aatttccttt tatcaaatag
    19021 aatttggagc atgatatgga aaaacaaaca agaagtgcac gacgaaaaga aaagccaaaa
    19081 gcgaaccagg cagattcgaa tttggtgctt gacctgtttc taaaactccg ctatcttatt
    19141 ggcgttttag tcatcgtggt catcgttact tttaatttaa acggaagttc acttggtgtt
    19201 tgggataaat atgtgtcgca aagagacgat gggaaaaaaa ctgatgtgat ttttggacag
    19261 aatcgggaag tgcggtcaga cgaatggctg gtgcagacac ctttttacct ctcacaagct
    19321 gaagaggact ttccgttggt gaacgaggat tattcattaa acggacaaaa catgatcatt
    19381 gcgtataatt ctcctgtaaa ggatattacg gttatcggaa aaccattcaa ctggggattc
    19441 tttttcctcg gaagagatcg aggactttcc ttttattggg cgatgaaatt agtcgtcatg
    19501 gtcttgcttg gattcgaagt actgatgata ttaacgaaga gaaaaaaagc tctatcgcta
    19561 atcggtgcat ttgcgctgac attttctcca gcagtccagt ggtggttcat gcaacatgtg
    19621 ggcgatttga ttttctttac tttgggactg atgactgctt tttatcatta tttctacaat
    19681 catgataaaa aatggctacg aacgttgatg atgcttttgg tggttatttt cggtattggg
    19741 tttattttag tgatttaccc agcccatcaa gtgatgctgg cgtacttgct gattttttat
    19801 tttgttggcc tgcttattta ctatagcaag aaagtttcat gggatctgtt ggatgtagtg
    19861 ttgattggag gggcagtttt atttattggc ggagtcatgg ttcatttctg gctaacgtca
    19921 aaagacgcat tgttagcttc tttgaatacc ttatatccag gaaaacgggt aagtactgga
    19981 ggaaagtgga cgattggcga atttttttct ttccttacaa attggaaaat tccttttgaa
    20041 gatatcaact attcgaataa ctctgaagtg gccctgttct atcacttttt tccaactgta
    20101 ttcctagcaa gtccatttgt gttatttggc aaaaaagata gcgaacaaaa gttactggga
    20161 cgtattttga tgattttttg tctgttttct atcttttgga ttaccgttgg gttgccaaaa
    20221 tggctagcag aaatcactct gctgtcttat gttcctccat taagagccat ccttactttt
    20281 agttttgcgg cttgtttatt atcgatctgg tttatcgctt atatttggag agaagatgtt
    20341 attcctattt ggtataaatt cattttgttg gcagtaaatg catggtctta tttctatgcg
    20401 attacgcatt cgaaaatgga taattatttt tcggattttg aaaccatcgc agttgctgtg
    20461 ttgggaacag tgattttagc ttttgcatta tttggctgga gacgcttgtt ttacctcgct
    20521 tttgccgcct tagttatcgt atctggcttt ttcgtcaatc cagtcgtaga aggtacagga
    20581 gcgatttttg aaaaaacact ggcaaaagaa atccaaaaaa tcgatcaaca agatcctggt
    20641 aaagtttggt tgtctgaaga tgaattatat aacttcaccc caacattggg agtgaaatcc
    20701 ttcaatacag tacgctttta tccagatata gctgcatgga agaaaatcga tccgaaagaa
    20761 gaatacgaga agtattataa tcggtatgct catacaagag cttttatcgc taaggaagat
    20821 acaaagttca ttttagatcg tccagatatg ttttcggtca cgttgaattt tgaagacgca
    20881 gaaaaattag ggatcgacta tgtgatcagt aaacgaccat taactgatta caaccaatta
    20941 tatgaagcgc agttcacgca gctatatgga ccggataaag acggttatat gatttttaaa
    21001 gtagaatatc cggattatcc agatgtacca caaacacaaa ctcaggaaaa tcagctagtc
    21061 gtacagtaat aggctagctg agaataatcc tgaaatgtta gtagaaagga gagtggagat
    21121 aattcaagca atcgtacaaa aatttgtcaa caaaatgagt gtcggtttct tgcttttgtt
    21181 actgacgcta gtcttttttg tttggacagc agggttaggt tttccagcaa ctttgtttat
    21241 atataacaat agttcattac ttatcgcttt tagtgtggct attttgctca ttttaaatgt
    21301 ttataaagca aaaggcgtcg attttcttta tctaggtgtt gcgcttgccc ttttcatttt
    21361 cttttcttac tttcgggaat taagaaatga gtctttattt ggagacttac tgtttccttt
    21421 gattatttta ttttgtttag taattaaatg gatcgagtgg acaaaatggg atcgcggtat
    21481 ttatctgatt gtcttttcgg tcttcctcgg aatcacgtta tatcgtgtat ttacagagat
    21541 ccaagtacca gaaggacaaa gcatctgggc tccaggcaat tcgctttctg atatttggat
    21601 caatacgaat ataatcggaa gttctttgat gactcttgct ttattgatca gtggatttgc
    21661 cagttctttt gaacgatggt atgtacgaat catcggtgca gtagcagttg ttgcagcttt
    21721 tctcgggatt tgggtctgcc aatctagagg tgcattagtc gcgttgattg tttttgcgat
    21781 attggatctt ttacctaaat cgttgatgcg tgtcattcgt gcgccattta ttgcttacac
    21841 ggttacgatt cttttagctt tgccgatttc ttatctggcg gctgtctctg aaaaagtcaa
    21901 tttgtttacc ggtcgagaag atatttggca taaattctat cagacgctag gagaaaaatc
    21961 tgaacaaatt ttactaggaa tgaaaacatt tatcttccaa cgaggaaacc aatttttagg
    22021 aaaccacaat agttataatt ctattttgaa tatctatgga ttgataggat ttgggattgc
    22081 tgctttgctg cttatccttt ttattggtcg cttaacgttg aaagcagatt tatccaacgg
    22141 gcagatgact tttatctggg ccttttttgc ggtgatgatg cagtcattta tggaggatac
    22201 attgacttca tacccatggg ttccgattat ttatatcctg ttggctatgg ccgttcatcg
    22261 atatgatgaa ccagaagttg cggaggaatt ctatgttatg gaagaggcat atgacgatat
    22321 gacttatgat gatacatctt atgaggaaca accagatagc gctcattctt ccaggatcca
    22381 acgctatcat tgataggcac aaaatacgag agaggctgtg acaaccgtcg cagccttttt
    22441 tggtttattg caattgtcta gcatcttctg taaaatagaa acgttagaga aaatcttgta
    22501 tcatagaaaa ttaagaaaga aataagaacg cagctcggta ccaaaaatat ggtaaaatgg
    22561 cacttgactg taattcactg aaaatcgctt ggaggaacac aaatgtttaa agatttgtat
    22621 ttatttatga aggacattta tcagaacaga aaattattgc tacagttttc gatcaatgac
    22681 ttcaaatcaa gatatgcagg atcgttttta ggaatcttat gggcgtttat caatccgcta
    22741 tttactgtat tgatttattg gctggtattt ggtgttggac tgaaagcaca aatgatcgat
    22801 gcaaaatacc catttatcgt atatttagtt accgggatga ttccctggtt cttcttctca
    22861 gatgcatttg catcaactac ggttgttttt cgggaatata cttatttagt aaagaaagtc
    22921 gtattcaata ttcgtatctt gcccacgacg aaaatcctat ccaatctgta cacccactta
    22981 ttcttcattc tgattggcat agctgtcgcg cttataaatg gtatatatcc ttcagcaatg
    23041 tctttacagc tgatttatta tttattttgc atgtgtgctt tcttgacagg attgacttgg
    23101 ctgacggcat cgatccaacc atttttacct gatatcatgc aattaattac gatcgtgctg
    23161 cagttgatca tgtggacatt accgatatta tggagcccta atcagtttga ttcaggtctt
    23221 gtaagcatat tgaaattaaa tccgctgtac tatgttgttc aaggttatcg tgagtcattt
    23281 ttaagtgaag cttggttctg ggagcatgga acatatactt tgtatttctg ggttttcacg
    23341 ttagtaatgt tcgtaatcgg ctctgcagtg ttccgtagat tgaaaccaca tttttcagat
    23401 gtgctgtaag gagaatagct atgacagaat atgcaattag actaaaagat atcacaaaat
    23461 cttataatat gtacgcaaaa ccttcggatc gatttcgtga agccctcaat ccttttaaga
    23521 aatcctatca tgatgtattt tatgcgttga aaaacgtgaa tgtagaaata aaaaaaggtg
    23581 agatgatcgg tttcgtggga gaaaacggat cgggaaaatc tacaatgttg aaaatcatta
    23641 cgggagtact gacaccaaca tccggcacga tggaaatcga aggaaaaatc tcagctttgc
    23701 tagaactagg atcaggattc aatcctgagt attctggcta tgaaaatatc tatttaaatg
    23761 gaatggttct aggattttca agagaagaag tcgatgaaat ggtcgatgat atcattgaat
    23821 ttgctgacat cggagaccat atttatcaac ctgtaaaaac ttattcaagc gggatgttcg
    23881 ttcgtctagc ttttgctgta gcaatcaatg tgaatcccga tattttgatt gtggatgaag
    23941 cattggcagt aggcgatctt gaatttcaac taaaatgtat ggaaaaattt acagaaatca
    24001 agaactcggg aaagacgatt ttattcgttt ctcatgatat cagttcgatt cgtcgttttt
    24061 gtgatcgttc ctattggttg aaaaacggag aagtcgtcga atatggcgat acgatggaag
    24121 taacgacgaa ttatgaaaac tttttaaaga aaaaatcagt taaaacagtg gatcggaata
    24181 aaaaccaagt agaacggttc gccgctccag atatcgtcga cgtgacgaaa gcggaattgt
    24241 tggataaaga caaaaatccg gtggatatgc tggaacaagg agaaaaacta tacgttaaag
    24301 taacttatga agtaaaagat gatacaatca aaaatccggt tttaggaatt gcgctacgaa
    24361 cagtcgacaa tttttatgta tgcggactta atactctact agatggtatc aagattcctt
    24421 ggaaaaaagg agagaatatc ttttatctgg agtatgaaaa gttaggtttg ttagctggtg
    24481 aatattattt tgacgttgcg gtctttgaag aaaatgcaac ggttcctttg gtatataaga
    24541 caaagtacat gaacttgttt gtcagcggtt cttatatcgg agaaggcatc gtggtcttag
    24601 accataaatg ggaagaaggg actcatagca atgaaatatg attttgaaat ggacctagat
    24661 gaacaaagca gtgtgggaaa aattgccgca cagatcaaac caggaagtaa agttttagag
    24721 tttggtcccg gaaacggccg attaacgaaa catttaatcg gagcaaaaca atgtgaagtg
    24781 agcattgttg agttagataa ggaattgttc gattttgtca gcgaatttgc tcaagatgga
    24841 ttttatggtg atatcgaaag ttttgagtgg gcaaactatt atgctggaca gacatttgat
    24901 tacgtcttgt ttgcggatgt tttagaacat ttggtagatc ctggaaaaac attgaagaaa
    24961 gtcagagaat ttttgaatga agaaggagag atcctgatta cattccctaa cttggcgcat
    25021 aattctgtca tgatcgattt gttcaataac caattgccgt gggcttctta tggtctccta
    25081 gatgaaaccc ataattcttt ttatactcat gatggcttcc aaaaagtttt tgaaaaagcg
    25141 ggattattca ttaatattga agattatttg tacttagctg taggtgatac agaattaaaa
    25201 tcaacttatg aagaattgcc ggaagctgta cgctatgatt tcaaaatgcg accatttggt
    25261 gaagtctacc aatacttttt ctcattgatg aaacatccag tagcacaaag ttccattgca
    25321 gagccacaaa attctaatta tgtaaaagtg ttagaagtaa cccagcaaac gaaacaagat
    25381 gaaacaatcc aacaaatacc attcaataat ttcacagggg aaaatgagac actaagtttc
    25441 cccgtatcag aaacaacaga aagaatggtg tttcgcttcg cgcaacaacc tagctttatc
    25501 gaattcagcg cagaagctgc cggagaaaaa ctaacattta tcgattcgaa tgctgtagtc
    25561 aaaacagtaa atgattgtta tttgtttgat gggaaagaat taccagagtt cgttctaacg
    25621 gatatttctg ggaaagaagt gactatccat tgtcactatc gctttatcgg ggaattgaca
    25681 ccaacaatga aagaattgtt ggaaacgatt cgtcccatgg ctgaagtcac aaagcagctt
    25741 tctgagaaaa atgacgaatt agaaagagaa aatcatcatc ttcttgagga aaatacaaga
    25801 ctagaccata cgttaaaaac aaccacaaat cgctattgca cattgttgga aagtgatgaa
    25861 tggacaataa aacatagact aggacgacgt aagaaagaaa cttcgaaaaa aatccaagaa
    25921 aaagaacttt ctatatgtat tgacgagaaa atctgggatg cagaaacaaa aatattaaaa
    25981 atcatcggat ggggaatcgc taattcggat cgccagccct tgtcctataa gttatcagct
    26041 gaccaatcgc catttttcga agcaattcct gtttcacgag aagaagtcaa tcaagcagaa
    26101 cagctcgcaa aaggaacaga agcgggattt gagttacgaa tcctttgcga gcaagaacgt
    26161 tcattcttag tggaagcagt agctcaaaat ggccaatcat ggatcattga aatgtaaata
    26221 atgattaact tataaagata aggagtaaac gaatcgtgca aaaaaaagaa attgccgtat
    26281 ttatcgatca aatcactcgt gaacgggcca ctggcgattt gcttattgtg ggctgggcaa
    26341 ttgatgaagt gaccaaagaa atccctacga taaaggtaga aaaagaaaat gtgattgctg
    26401 aagcaacaca tgtcgtaaga ttggatatca atcatttata taatcttgat gttaagaccc
    26461 aaagcggttt taaggtacgt ttatcaggga aaatgagagg aaaagccatc ttagacttcc
    26521 aaacagcgag acatcaaaat ggcatagctg tgaaattaaa cggtaaatac ccttatgatg
    26581 acggcattga atcttcatgg gaaagaaaaa aaagattact gaaaaaaggg ataaattatg
    26641 caaggactca tggcgtaaaa aaagcgatcc gtcgggtcaa attggaattg aagccaggat
    26701 cgatcgacta tgcagagtgg atcagtcgtc atgagaaacc agatttgaaa gagcaaagga
    26761 aagaagcaca aggatttgcg taccgtccat tgatttccat acttatgcct gtctataacg
    26821 ttgaaatcaa atggctcgaa aaatgcattg attcggtact ggatcaaacg tatgatcatt
    26881 gggaactatg tatcagtgat gatgcttcta ctgatccagc tatccgaaag tgtctggaat
    26941 cctatcaagc aaaagatgat agaatcaaag tcgttttccg aaaagaaaat ggacacatca
    27001 gtctggcaac taattctgca ttggaaatag cagaaggaga atttatagca ctcttagata
    27061 atgatgatga attaccgcca tttgcattat atgaagtggc aaaagtgcta aacgtacatc
    27121 cagaactgga tgtgatctac agtgacgaag ataaaatcga tgcagatggc aatcgctttg
    27181 atccgcattt caaagcagac tggtcgcctg atacattgat gggaaataat tatatctctc
    27241 acttaggcgt atatcgaaca agcattgtta aagaacttgg cggtttccgt aaaggctatg
    27301 aaggttctca agattatgat ttggtccttc gtgtgacaga acaaatccct gcagatcata
    27361 tttaccacat tgaccgagtc ttgtatcatt ggcggacgat cccaggatca actgcaagta
    27421 atggcgaagc caaaagttat atctatgatt ccggagtgaa agcattgaca gatgccctgt
    27481 ctagaagaaa catcaaagga agcgtacgtc ctggcagaat ttctggattt tatgagattg
    27541 cttatgacgt cttgcaagag gatttggtca gtgtgatcat tccaacgaag aatggctatg
    27601 aagatctaaa aacttgtgtg gattcgatca tcgaaaaaac gtcttattca aattatgaaa
    27661 tcattattgc ggataacgga agtacagatc caaaaatgca agaattattt gcagaataca
    27721 agcatcagct gaaagaccgc tttatcgtag aattgattga cattccattc aattattctc
    27781 gaattaacaa tttagcagca gaaaaagcaa acggcaaata ctttttattc ttgaataacg
    27841 atacagaagt gattgagcca gattggatga cggtgatggt ttcttatgca cagtttgatc
    27901 gaatcggctg tgtaggagca aaactgtttt atccagatga tacaacgcag catgcaggag
    27961 tattattagg aatcggtggt gttgcagggc atgcattgaa taactatgat cgaacacatt
    28021 gtggttattt cggccgattg gtcattgacg tcaattactt agcagtcact gcagcttgta
    28081 tgatggtcaa ggcagctgac ttcaatgctg ttaacgggtt tgatgaaaca ttagaagtag
    28141 cattcaacga tgttgacttg tgcttgaaag tttatgaact gggtcgttac aatgtctatg
    28201 cacatcaagc agaattgtac catttcgaat ctaaatcaag aggttatgaa gatactccag
    28261 aaaaacaaag acgttttgct ggtgaaatca aaaaaatgca agataaatgg ccagcatata
    28321 ttgcgcatga tccattttac aatgataatt taacaaaaga aggaatcggc gacttttcgt
    28381 tgagaccaga ttaaactata ataaaaagct gttatgttgt gattcgctcg cacataacgg
    28441 ctttttatag ttttttgtca aaaaaaggca gaaggtgccg actcaaaaaa ataagtcgag
    28501 gttgggacag aagtgtttaa ctccgagaaa taagaagaaa ttcacgaaaa ttgcttttca
    28561 aatttttgtg aatttcggct tatttaagaa gaagttgctt ctgctcccac cgtttattcg
    28621 tttttaaaga atgagacaaa agtgtttctt acttttgtcc cacgctctta ttcatgctca
    28681 gagcgccaat agatacaaaa tcatagccaa agtttcacga accctagctg tcaaagaatc
    28741 gatattttat tttaatatag gctattttaa aataaatggt ttaaggtatt cctctacaaa
    28801 agccactcta tcaattatca tgggtttaaa ataagaagtg atggagataa ccagattgtt
    28861 cttagcgtca atataaagaa catttccact attaccaatt gctgaatata tttcgttctc
    28921 agaatctaat acccaccata aatagccata tctcatattt tgtaagtctt ctaaagcact
    28981 ggttctaggt ttgaacatct cgtttatcca catgggtggt acgatttgtt ttcctttata
    29041 catcccttta tttaggcata atacaccaat ttttgccaga tcacttgccg ataaacacaa
    29101 accatatcct gccgtcccga tatttagtgg atcacaaaac cagacattgg ttttaggaga
    29161 cttatccatt gtaaactgct tatgttcttc agctgtttca gcataataat tgacatggtt
    29221 tggtatccct ataggatcaa atagatactt attggcaaaa tcaacagttg ttagcttact
    29281 tgtctgatac aacaagccag ttaatatgtg taaacagaca gtttgatagt tgaattcgcc
    29341 ggttatacct tttcttcctc ccaataaatc tagtgatgtt tttgtccaat cttcacttga
    29401 acagactttt gtccatggat cgcctttaca tttgtagggt gctttcattg ttagcaagtg
    29461 cttgattgta atagcgtaaa tagttttctc cccgcgtttc actttatact ctggaaaata
    29521 atctaatact ttatcatcga tacttttgat taatccttgc tctaaagcaa tgccaatcag
    29581 caaagataca atacttttcg ttgctgacat gatatgacaa gtatcgtctt ttttataacc
    29641 attccattca tctgtataaa cttctacccc atccttatat gcgacaattt gacatatatt
    29701 tggttgtcga aaaccaataa aatcatgcaa ctcttgttta ttcataagat attacctcac
    29761 tttcttctat aagcataatg tcattaaaaa tcgatttcaa ttttttcgat tcttcacgta
    29821 atacaggtat tcttatggac tagacagcgc tttgggaaga tggattctct gaaaaatata
    29881 aaggttcact ttatgagtgg ataaaaaaag cagcaaatac ttcgacttct ttaatttacc
    29941 aacattagtg aaaatcgatt catctggaga tttgtaattt agagtccttg tcttgattag
    30001 aggtgtataa agctttttat tagacatttt taaattccat tacaatttgc ttataaacta
    30061 ggtttttaaa ggtgactatg gtaagataat agagatatta ttttgtgatt aggagtgtat
    30121 atatgaataa aaatggagaa tggagtgctg cacgacggat attcattata ttaatggatg
    30181 ttattgtata caatgcagca atatatagta gtttcttact gaagtttcgt ggagagatcc
    30241 cattacgaaa tttagaaact ttccaacact cagcaattat tatttcagtg atttttattg
    30301 cgttgaacat tttgttgggt gcatatgttt tttataatcg aatgatcagt gacatcgtgt
    30361 ttgtcacagt catcggtcag gtattgatga cactagggat catggtagtg acttttgcgg
    30421 gccgctggtt tgcttttcca cgtcttgtta tcttactttc atttgttctc ggtacgcttt
    30481 tcttaagtat ctatcgtatt ctcgtatata aactttattt acgcgtaagt cgagataaaa
    30541 aggtcgtcat tattgggtta gaaaaggatg tcgcaccagc aatccaaaat tttggttcaa
    30601 agaaaaacaa caaacataaa gtcgaagcag tcattcttga taactattat gcaaacatca
    30661 aaaatatgat taaagacatc gatattgtct atcttgcttc tcatatcgaa gaaactgaaa
    30721 aaatcaaaat ctatcaatta gttactaaaa atgaaaaaaa attgtttttg aatacaacat
    30781 ttgaaaactt gacattgatc aatccaaata ttatgaattt cgaagatgaa agtattattg
    30841 aagcatctgg atttagaatc caacctgaat atgaactatt caaacgtttg tttgatatca
    30901 tcgtttcact tgttttatta gttattgctt caccatttat gttattcaca gcaattttag
    30961 tcaaagtgac atcaccggga ccaatcatct ataaacaagt gcggatcaca aaaaatcaaa
    31021 aggaattttc aatctataaa ttccgctcga tgaccgccac agccgaagca aaatctggac
    31081 cagttttagc taagagcaat gatgcacgag taacgcctgt aggtaaattt attcgagctg
    31141 tccgctttga tgaattacca caaatcttca atgtgctgaa aggcgatatg tcgatcgtag
    31201 gaccacgtcc tgaacgtcct ttcttcgtcg atcagttcaa tgcagaaaac ccttattact
    31261 acttacggca taatgttcgt gctggtatca ctgggtatgc acaagtctat ggaaaatatg
    31321 tctctgatta caacagtaaa ttacgttttg atttacttta tatcaaaaaa tattcattga
    31381 tgcttgattt aaagatcttg ctgcaaacca tcaagatcct atttgataaa atgtcctctc
    31441 aaggacttga agaagacgaa aatgtgatct cattggcaga aattgctttt ccgaatgaaa
    31501 aaatctttcg ctagttggga ggcgtaaaaa tgaacaatcc gaaattcagc ataatcgtac
    31561 cagtatacaa tgcagaagca actattggtc gaacgattga tattctaaaa gaattggatt
    31621 atgaagagta cgaagtcgtt ttagtaaatg atggatcaac agatcaaaca caggaaatca
    31681 ttcaagaact gattgaaaat gatgaacgtt ttgaattgat tactacgacc aatcaagggc
    31741 ccggattagc aagaaacgaa ggaataagac agtcaaaagg agaatatctc ttattcttcg
    31801 atgcagatga cacgccagta aaaacgatct tgtcagatta tgatcatttg ctagaaaaga
    31861 gtccaaaagc ggatcttgtt gttagttcgt ttgtttttcg tacaatggac gagggaagaa
    31921 tcgtttccga aaaagaaaac ttagttacag aatgtcacta tctaactcac gaagagttta
    31981 taaaagacat gtatcagtta atgaatgaac agttgatgta tgttgtatgg aacaaatgct
    32041 atcgtagcga tattctgaaa aataaccaaa ttctatttaa aacttataat agttgtgagg
    32101 atcgaatatt taacttacat tattatgaat actgtcatca agtgatcatg aacccaaaag
    32161 tagaatatat ttatgaattt gaaggtggga aggggatcac taatcaatac cgacctaaca
    32221 agttcgaaac atttaaagaa ttctattcat tagcaaatac tgtaacagac gatattaata
    32281 aagacggtat ggcggcgctt cttttaaaag ggacaacttc agttattttt tctatttata
    32341 gtacctctgc aagaacttca aaagagaaga aagacgaagc aaagcagata ttgagtgatc
    32401 cagtgatccg agaagccaag caaattgcta agacggattc ttcagcaaaa aaaataacaa
    32461 agttgcttta caatatgcca gctccactat ttttatctgc tgtaaaagtt ggaagcttcg
    32521 ttgaagtgaa aatgccaggg ttaatggctg ctttgaagcg agtatattag ttaatggagg
    32581 aaaatataat gaaaagaatt ttgcattttc agggacgaat gggtttaggt ggagcagagt
    32641 ctttcatgat gaatttatat cgtaaaattg atcgtacaaa ctatcaattt gattttttga
    32701 tttatgaaga ttatgcagat gttcaagact atcattcaga gattgaaaga ttaggaggcc
    32761 gtatttttgt tgtacctaat cctaagaaaa atatttttaa atatttaata gaagtgaata
    32821 agttactaaa aaaagaatct ttttctatag ttcacaatca ggtttatttt ggcgggggaa
    32881 ttaatttatg gttagccaaa aagaatggaa tcagacagag aattgctcat agccatgcaa
    32941 ctgaagatgg aaaatctcaa aatattgtaa tgaatgtatt gcgtaaattt ttaaccaaat
    33001 tgttgttaca aaatgcaaca gactaccttg ccgttagtca agaagctggt gaaagtctgt
    33061 ttcaaaacca cccctttgag atagttcata atggtattga tttagagctt tatagtaaaa
    33121 attcagaagc taaggttaat aagagaaaag aattggatat ctcaatgagt acttttgttg
    33181 tgggaaacat tggacgatta gagaaacaaa aaaatcaatc ttatttgtta gagatttttt
    33241 tagaaatact aaaaatgaat tctgattctt acttgatttt agtaggtgaa gggtcactta
    33301 gaaataaact gaaagccaaa gcagtagaat tggatataga gaaaagagta aaatttttag
    33361 gagaaagaaa cgatattccc gagttattat ctgtgatgga tgtttttgta atgccttctc
    33421 tttatgaagg tctgccaatg gttggattag aagcacaagc agcaaaatta aaattagtct
    33481 tagcagatac tatttccaaa gatacaaagt taacaaataa tgtggatttt gtatcattag
    33541 atgaaacacc acaagaatgg gcaaaaaaag taataaaaga gccgtatgct aataaaataa
    33601 cacaagaact aaagagttat gatgtttcgt acactactga acaaatggag agtatatata
    33661 gtagagatca ttaaaaatgt tcaagatatt ttaggagtga ttatttttga aaatatgtta
    33721 tttgatattg gcatacaatg atattggcaa cttaaagaga ttggtcaatc gattgaacga
    33781 aaatgcagtt tttattattc atatagataa aaaaactgat atagaaccat ttattgaagc
    33841 atttaaatca tatgataatg ttgaattttt atgtaataaa aaccgtgtta aaatttattg
    33901 gggtggtttt tccattgtac aagcagaaat caatttagta aagagagcat tacaaaatg
//
LOCUS       DAZUJR010000024        33842 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.024, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000024 DAZUJR010000000
VERSION     DAZUJR010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33842
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.024"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(26..145)
                     /locus_tag="ACG804_001055"
     CDS             complement(26..145)
                     /locus_tag="ACG804_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HFS4832001.1"
                     /translation="MVFQKPLNNFRYIVYYCHTKIKKNKQKETVTKVLSQSLI"
     gene            324..1985
                     /locus_tag="ACG804_001056"
     CDS             324..1985
                     /locus_tag="ACG804_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFS4832002.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(2055..2402)
                     /locus_tag="ACG804_001057"
     CDS             complement(2055..2402)
                     /locus_tag="ACG804_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HFS4832003.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSTLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            2486..3427
                     /gene="opp3b"
                     /locus_tag="ACG804_001058"
     CDS             2486..3427
                     /gene="opp3b"
                     /locus_tag="ACG804_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HFS4832004.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            3428..4471
                     /locus_tag="ACG804_001059"
     CDS             3428..4471
                     /locus_tag="ACG804_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4832005.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            4477..5547
                     /locus_tag="ACG804_001060"
     CDS             4477..5547
                     /locus_tag="ACG804_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4832006.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            5537..6490
                     /locus_tag="ACG804_001061"
     CDS             5537..6490
                     /locus_tag="ACG804_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4832007.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            6502..7512
                     /locus_tag="ACG804_001062"
     CDS             6502..7512
                     /locus_tag="ACG804_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HFS4832008.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(7797..8618)
                     /locus_tag="ACG804_001063"
     CDS             complement(7797..8618)
                     /locus_tag="ACG804_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFS4832009.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(8715..8993)
                     /locus_tag="ACG804_001064"
     CDS             complement(8715..8993)
                     /locus_tag="ACG804_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832010.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            9261..11270
                     /gene="metG"
                     /locus_tag="ACG804_001065"
     CDS             9261..11270
                     /gene="metG"
                     /locus_tag="ACG804_001065"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HFS4832011.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(11749..12336)
                     /locus_tag="ACG804_001066"
     CDS             complement(11749..12336)
                     /locus_tag="ACG804_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832012.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            12511..13833
                     /locus_tag="ACG804_001067"
     CDS             12511..13833
                     /locus_tag="ACG804_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFS4832013.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            13988..14764
                     /locus_tag="ACG804_001068"
     CDS             13988..14764
                     /locus_tag="ACG804_001068"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFS4832014.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            14757..15326
                     /gene="rnmV"
                     /locus_tag="ACG804_001069"
     CDS             14757..15326
                     /gene="rnmV"
                     /locus_tag="ACG804_001069"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HFS4832015.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            15319..16203
                     /gene="rsmA"
                     /locus_tag="ACG804_001070"
     CDS             15319..16203
                     /gene="rsmA"
                     /locus_tag="ACG804_001070"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HFS4832016.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            16654..17283
                     /locus_tag="ACG804_001071"
     CDS             16654..17283
                     /locus_tag="ACG804_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832017.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(17407..18516)
                     /locus_tag="ACG804_001072"
     CDS             complement(17407..18516)
                     /locus_tag="ACG804_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4832018.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            18725..19147
                     /gene="mgsA"
                     /locus_tag="ACG804_001073"
     CDS             18725..19147
                     /gene="mgsA"
                     /locus_tag="ACG804_001073"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008929 - methylglyoxal synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006007 - glucose catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019242 - methylglyoxal biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HFS4832019.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     regulatory      19334..19432
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01831"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="THF riboswitches regulate genes encoding folate
                     transporters and folate metabolism; They are most commonly
                     found in Clostridiales and Lactobacillales; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="tetrahydrofolate"
                     /db_xref="RFAM:RF01831"
     gene            19470..20006
                     /locus_tag="ACG804_001074"
     CDS             19470..20006
                     /locus_tag="ACG804_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HFS4832020.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(20046..21809)
                     /locus_tag="ACG804_001075"
     CDS             complement(20046..21809)
                     /locus_tag="ACG804_001075"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4832021.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(21812..23527)
                     /locus_tag="ACG804_001076"
     CDS             complement(21812..23527)
                     /locus_tag="ACG804_001076"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4832022.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(24306..24530)
                     /locus_tag="ACG804_001077"
     CDS             complement(24306..24530)
                     /locus_tag="ACG804_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832023.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            24721..27498
                     /locus_tag="ACG804_001078"
     CDS             24721..27498
                     /locus_tag="ACG804_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFS4832024.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            27579..27998
                     /locus_tag="ACG804_001079"
     CDS             27579..27998
                     /locus_tag="ACG804_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFS4832025.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            28010..28480
                     /locus_tag="ACG804_001080"
     CDS             28010..28480
                     /locus_tag="ACG804_001080"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFS4832026.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            28497..29276
                     /locus_tag="ACG804_001081"
     CDS             28497..29276
                     /locus_tag="ACG804_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFS4832027.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            29263..30084
                     /locus_tag="ACG804_001082"
     CDS             29263..30084
                     /locus_tag="ACG804_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFS4832028.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            30101..31150
                     /locus_tag="ACG804_001083"
     CDS             30101..31150
                     /locus_tag="ACG804_001083"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFS4832029.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            31163..32167
                     /locus_tag="ACG804_001084"
     CDS             31163..32167
                     /locus_tag="ACG804_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFS4832030.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            32800..33819
                     /locus_tag="ACG804_001085"
     CDS             32800..33819
                     /locus_tag="ACG804_001085"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFS4832031.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
BASE COUNT        11048 a         5997 c         6912 g         9885 t
ORIGIN      
        1 aaactggctt ttgaacaccg tttattcaga taagggactg tgacaagact tttgtcacag
       61 tttctttttg tttattcttt tttatctttg tatggcaata atagacaata taacgaaaat
      121 tatttaatgg cttttggaag accatggaaa accttgtaca aagctatttt ttctgaaaaa
      181 ttccttgaaa cctcacgaaa aaatcattat tttatgaaaa agacaaaaaa aagtgttgat
      241 tttttaataa ttattcatta aactcttaaa caacttcaga aaatattaat tattctgaaa
      301 attccaataa aggggtacgt aaaatgaaaa agaaatttac atttggtttg gttgcggtat
      361 gcggccttgt acttgctgga tgttatggcg gcagttcagc cacaagcagt agttcagcaa
      421 aaagcggttc agcagatgga ggaggcgtat ttaacttagt cgtgcctcaa gaaatgccta
      481 cagctgactt atcagttgca acagatacaa tcagttttac agcattgaat aacgtttatg
      541 aaggaattta ccgtcttgat gaagacagca aaccacagcc ggcaggagct agcgagttgg
      601 cagaagtcag tgaagacgga ttaacttaca aaatcaaatt acgagaagac gcaaaatggt
      661 caaatggtga tcctgttaca gcagcggatt acgtttatgg ctggcaacga acagtagacc
      721 cagctacagc ttctgaatat gcttacctgt atgcgccagt tgaaaatgca gaagacatta
      781 cagctggaaa gaaagataaa tcagaactag ggatcaaagc agttggtgac tatgaattag
      841 aaatcaaatt gacgaaacaa acaccatatt tccaatatct gcttgctttc ccatcatttt
      901 tcccacaaaa acaatccgta gtggaagaaa atggggatgc ctatgcatct gcaagtgata
      961 aagctgttta taatggacca ttcacattag aagattttga tggaccagga acagatacag
     1021 aatggactta taagaaaaat gatcattact gggacaaaga tacagtaaaa ctttctgaaa
     1081 tcaaagtcag tgtagtaaaa gaatcttcta ctgcattgaa cttattcaaa gatggccaag
     1141 cagatgacgt gatcttgtct ggtgagttag cacagcaaaa cgcaaacgat ccagcttata
     1201 cttctgttaa agaagcgcgg acaagctata tcgaattcaa tcaacgtgaa aagaattcac
     1261 cattcaacaa tgtgaaccta agaaaagcta tttcttattc tatcgatcgt gaagctttag
     1321 taaaacaagt actaggtgac ggatcagttg tctctacagg attgatccca tcagatatgg
     1381 taaaaagtcc aacaacgaac gaagactttg caaaagaagc tggaaaatta gtttcttatg
     1441 acaaagataa agcaaaagaa tattgggaaa aagcgaaaaa agaattgggc gttgattctt
     1501 tagaatttga tttgatggct tctgatgatg attcatcgaa aaaagtaatc gaatatgttc
     1561 aaaactcaat ccaagaaaac ttggatggcg taacagtcaa accaacacct gttccattct
     1621 ctgtacgtct tgaccgctca acttcgggtg attttgacgc agtactaggc ggatgggctg
     1681 ctgactatgc agacccaagc agctttactg atttgtttgt cacaggtaat tcatacaacc
     1741 gtggtcgctg gagcaatgca gaatatgacg aagcagttaa agcagcttca tcaacagacg
     1801 ctggcgatga acaagcccgt tgggatgatt tccaaaaagc aatcaagatc atctctgatg
     1861 atatgggtgt cgttccggtg taccaaaaag cagaaggtca cctagtgaat gaaaaaatca
     1921 aaggtatcgt tcaccatgcg gcaggcgctt catgggatta caaatggaca tacgttgaag
     1981 aataatcgtt aataccgtga gcatgagaaa aaacgaggct gcggcaaatg tcgcaacctc
     2041 gttctcatat tcacttatcc taacaaagaa aaaagcatga aaatagcaga aagagcaatt
     2101 agtattccgg caatgatcag ccaaaagctg tacataccgt agctggcaga cgagagcgtg
     2161 gaaaattctg gttttttctt tcggttcctt gttcgtgcaa gatggaccga tcgctgaaaa
     2221 tgatcgaaga aacccgaaga aaagacccat aaaaaaccgc cgataatcag aaacggcaat
     2281 gaccataaga atagatcatt agataattga atgagtgtaa aggaatggtt gatgagattt
     2341 tttattaaaa taaccagaat cagtagaaaa gctactgcgt aggggataga tttttttttc
     2401 atttgattgc tcctttattt ttggttcatt atctaataat gtagcgaaac atctgtcaga
     2461 agtcaaaagc tagggggaaa cattagtgaa tagttatatc aaatatgtat taaaacgtgt
     2521 ctttttcatg atcatcacgc tttggttaat tgcaacaatc acctttttct tgatgcaatt
     2581 gctgccgggc acgccatata cgaatcagga acgtttgagt cctgaaacaa tcgagatgct
     2641 aaataaacaa gtcggtttgg ataaaccagt tatcgtacaa tatgggattt atctttctaa
     2701 tttgcttcaa ggagattttg gaatttcctt ccaatttaaa aaccagccag tcgcacattt
     2761 gttagctgga agaatcggac catccttgca gttagggtta caggcaatta tctttggaac
     2821 agtcctaggg acgattttag gaacgatctc tgccatgaag caaaatacat gggcagatac
     2881 atcttctaca ctcgtagcga tattaggtcg ttccattcca aactttgtat ttgctgtttt
     2941 attacaatat atctttgcaa tcaaattaca agttttgcca atcgcaaaat gggatggctt
     3001 tgtgtacaca atcttaccaa caattgcgtt ggccatgtcg ccgcttgctg actctgctcg
     3061 gtttatccgt acggaaatgg tggaagtact gcatagtgat tatgtggaat tagcaaaagc
     3121 aaaaggattg agccgttggg aaatcgcctt taaacatggt cttcgaaata gtttgattcc
     3181 attgatgact ttattaggac cgttagctgt agcattgatg accggatcac tggtggtaga
     3241 aaatatcttt gctattcctg gtatcgggga acaattcgtt aagtcaatca caacaaatga
     3301 ttatcctacg atcatggctg taacgatcct ttactcattt atgctgattt ttgttatttt
     3361 gatcgtggat ctattgtacg gtctagttga tccaagaatt cgtgtttcag aagggagccg
     3421 aggataaatg gaaatgatac caaagcgtta tgaaacagtt gcagatatcc ctgcggatga
     3481 atttcttcca ttacaaaaaa ataccgaaga agaacgtgaa cagattactg caccttcttt
     3541 gaattttatc caagattcat ggcgccgttt aaagaaaaac aaagctgccg ttatttcaat
     3601 ggttttacta ttggtcatca ttttgatctc tgtgatcaca atctttgttt ctcctcatga
     3661 tccaactgcc caaaacgtgg cttatatcaa tttgcctcct cgtattccgg gaatcaatat
     3721 cgatggattg aatggaaaag caatggttgg tggtgaactt gttgataaat atgctcaagc
     3781 aaacgtccct tcaaacgtaa atttcttttt aggaacagac ggtttgggac gtgatgtatt
     3841 aagccgctta tttatgggaa tgagaatctc gttgctgatc gcatttattg ctgcattact
     3901 agatgtaacg attggtgtag cttacgggtt ggtttctggt ttgttaggcg gacgtgtcga
     3961 taacgtgatg caacgttttt tggaaatctt atcaggaatt ccaaacctcg ttgtcatgat
     4021 tttgatgttg gtcgtttttg aaccaggaat tttttcaatc gtggctgcta tggccatcac
     4081 aaactggata ccaatggcac gtatcgttcg tgcacaaaca atgaaattaa aagatcaaga
     4141 atatgtttta gctggattga cattaggtga atcaagaatg aaaattgcat tcaaacatat
     4201 tttgccgaat atctctagtg tcattattat tcaaatgatg tttagtattc catctgctat
     4261 tttcttcgaa gcctttttaa gctttatcgg tttaggtctt acgcctccgt cagcttcatt
     4321 aggaacgatg ttgagcgaag ggtacaagac attcctgtat ctgccttatc tattatggat
     4381 tccggcagta actttatcgg ttatcatgat tggctttaac ttacttgctg atggattgcg
     4441 tgatgccttt gatcctaaaa tgaaagagtg aagacgatga cgaaaatttt agaagtgaaa
     4501 gacttagaaa tctcttttga tacgtatgct ggaaaggtac gagcgattcg cggtgtcaat
     4561 tttcatttga ataaaggaga aacattggcg atcgttgggg aatctggaag tggaaaatca
     4621 gtgacgacca gaagcatcat gcgcttgctg tcaagcaacg ccaatataga tgctggtcaa
     4681 atcctcttta aaggtaacga tatcgttgga aaatcagaaa gagagatgca aaaaatccgt
     4741 ggtaaagaaa tagcgatgat tttccaagat ccaatgacct ctttagatcc gacgatgccc
     4801 attgggaagc aagtcgctga gtcccttaga aagcataata aagtttcaaa aaaagaggga
     4861 caaaaagctg cattagaatt gcttaaatta gttggaatac ccgaagctga gaaacgtatc
     4921 aacagttatc cgcatcagtt ctcaggaggt cagcgtcaac ggatcgtgat cgcgattgca
     4981 ctggtatgtt atccggaaat cctgattgct gatgaaccta caacagcgct tgatgtgact
     5041 attcaagcac agattttgga gctgctgaaa gaaattcaga caaaaatcga tacatcaatt
     5101 atctttatca ctcatgacct tggtgtagta gcgaatgtcg ctgatcgtgt cgctgtcatg
     5161 tatggaggaa gaatcgttga agttggaaca tcggaagaaa ttttctacaa cccgcaacat
     5221 ccctatactt ggggactgct tggttcaatg ccgacattag atagtgcgaa cgatcgattg
     5281 tatgctattc ctggttctcc accggattta ttgaacccgc caaaaggaga cgcattctat
     5341 ccaagaaatg aattcgcgat gaaaatcgat gcagaacaag aaccaccatt ttttgaacta
     5401 tcaaaaacac acaaggcagc aacttggcta cttgctccgc aggcacccaa agtgacaccg
     5461 ccagaagaaa tccaacgtcg ctgggctatc tttaaagaga aacaaaaaca tacttacggt
     5521 caaggaggaa ttgctgatgc caaataaact acttgaagtt aaaggattga aacagtattt
     5581 caatgtagga aaaaagaatg aagtacatgc tgtaaatgac atcagctttc acatttatga
     5641 aggagaaaca ttcggtttag ttggagaatc tggaagcgga aaatccacta ctggccgtac
     5701 gatcattcgc ttgaatgaac ctactgatgg tgagatatta ttcgacggtc aagatataac
     5761 gaagatcaaa gataaaaaag gtttgacgaa attccggcat gatgttcaga tgatctttca
     5821 agatccatac gcttcgttga atcctcgtat gaaagtcaga gatatcattg ccgaaggaat
     5881 tgatgttaat ggactagcta aatcatctga agagcgtgca aaaaaagtcg atgatctatt
     5941 gagaactgtt ggattgaatc caagccacgg tactcgttat cctcatgaat tttcaggtgg
     6001 gcaacgccag cgtattggta ttgcacgagc attggcagta aaaccgcgtt ttatcatttg
     6061 tgatgaacca atttctgcac tagatgtgtc gatccaagcc caagtggtca atttgttgca
     6121 agatctccaa aaagaacatc aattgaccta tctatttatt gcacatgatt tgtcgatggt
     6181 taaacatatt agtgaccgaa tcggtgtaat gcataacggc ttgttattag agatgggaac
     6241 aagtgatgaa atctataatc acggtgttca tccttataca gaaagtttgt tatctgctat
     6301 tcctctacca gatccagacc atgagagaaa acgcagaaga atcaaatatc aacctgaacc
     6361 agatgacgga caagtacgtc aacttcgtga aatcgcacca gaacattttg tctatgcaac
     6421 tgagcaggaa gtcccatatt acgcaaaaaa actaaaacga caaaaggaat ctcttctggt
     6481 tgctaactag gagggacata gatgctaaaa gcttttaaat tccgtatgta tccgacagaa
     6541 gaacaaaaac agcaattgat tcgtactttt ggatgtgctc gatttaccta taaccatttg
     6601 ctgaaaaagc ggcagaaaag ttggcaacaa acaggagtag ccaatttttc gctcacaccc
     6661 gctacattaa aaaaagaata cccattctta aaagaagtag acagtcttgc tttagcaaat
     6721 gcacagctta atttggatcg ggcttttcgc aattatttca agggacgtgc cagcttccca
     6781 aagcttaaaa cgaaaaaaag tatgtggcaa tcttatacga ccaacaacca aacccgtacg
     6841 atctatctgg aaaatggcta cttaaagtta ccaaaacaaa aagaactaat caagataaat
     6901 cagcatcggc cagttgaagg atcgattcgc tccgctacga tttctgctcg atataatgaa
     6961 gaattttatg tcgcactact ttgtgatgtt tcgccagtaa aaaaagaatc tttagctaaa
     7021 tggatcggga tcgcctatca tccgaagaca ttgatccaaa catctcgacc tctagaagta
     7081 actttaccaa aatttcacca gacagaagaa aagctgcaac atgcacagcg gaaattgaat
     7141 gtgaaagtcc gctccgctca ccatagaaag atcaggttag atcaggcaag caattatcag
     7201 aaacaaaaga gaaaagtaat ggatctttat ctgaaacaaa agaaccagcg agaagattat
     7261 cttgaacaat tatctgggaa attggtcaaa caatatgact acttatttgt agaatctttt
     7321 ccaaaagaag aggcacatgc tgatttttct attcacgact ggcataaatt aataacaaaa
     7381 ttgcgttata agtcccaatg gtataataaa aaatttcttt tgatcaatac cgacggagca
     7441 gaagaaagca attccgtaag aaagagccaa gtagtagaaa aaatgggcag acattcggtt
     7501 atcaagggat aaaaaatgaa tgaaactgat aggagcgtta gggttagcct tgttaataaa
     7561 aagtcttaat gacttttgtt tctaggaatt tttcttttga agaaaagctc actaattatg
     7621 acaaaccaat aaaacaatag cagaaaaagt tcgtacgagc tttttctgct attgttaatt
     7681 ttttattcag aaagtttacg aatacatcaa aattctgaaa caaaaaacgt aactcacaaa
     7741 gagttgtttt tgcgtttttt cttgaatgat taggtctgaa tcttttgctc acaaccttat
     7801 tcatggtgcc ccggcttgag ctgatagatt tttgaaggac ggccgattcc tacaggacgt
     7861 tcaccgatct catcgaaata ttggagcata gctttcttaa aattggaatg atcgatcgtt
     7921 ttataatcga tccctaagaa tttagcaaat acttttcgag cttccgtaat cgtgaaatct
     7981 ttacctaaaa cttgtagaac ttgcggctcg tgttccattt tattgactac acggttgaat
     8041 gctttcaaga tgatttgact atggtcaaaa gccaaagtat ctttgccaga agactctcca
     8101 gtgactaaat caagcgagat agccacttct ccgctagata aatggatctt gttactatga
     8161 cgttctagtg tgaaccagcg tacttccttg gcatcatctc cggcgattag cggttcttct
     8221 ccaataaagg ctaagtagct gactgtgacg acccagcctc gcggatctcg attaggcgta
     8281 ctgaatgtat gcagttgctc aatattttct tttgaaataa ccacaccagt ttcttccttt
     8341 gtttctctta agacgctttc tccagttgac tcatcctttt ggacaaagcc accaggcaat
     8401 gcccatgaat ttcgataagg atgccctttt ctttggatca acaaaacttt cagctgatct
     8461 tcttctttgt tatagcacat cagtacgata tcgacagtca aagagggctt gtcatattct
     8521 ggacgttcct gtttttgata ccagttaaga aattcttctt cacttgcttt atgttcataa
     8581 tataattttt cttcttcttt agaagcaaaa cggttcatct gaccacctcc attgacagta
     8641 aaagtacttt ttaccttatt gtagcagact ctgaaaaaaa accaaggatt tacttgaaaa
     8701 atctaggtta tcatttaaat atgaaaaata aatggaagta tgagattgaa taaaaagaaa
     8761 agcagataaa acggcaatac tttataccgc tcttcacgaa tggcaaagaa gccacaaata
     8821 acgatatata cgtcaatgat aaaacgcaaa atccaagctg ctgtcataaa actgttcaaa
     8881 tgcccatgga ggttaaaata accatacata cgaatataaa aatagctgaa tattaaatgt
     8941 gctaatgaaa gaaaagcaat actaagtgta aaaaaaagat gtttcttctg catgattgtt
     9001 ccagtccctt actaagatag atagtcttta ttataccacg tgtgagggga gaaataaaaa
     9061 gccgtttttt agtagatatg aaacaaaaca aaaacccgca tttattcaac ctattcatcc
     9121 ttttaaagga tagattgaac gtagatagaa gtcgtttatc cagtcttttt cattttgaaa
     9181 aaaagctaac agcatgcttt ttttatggta tactagcaag gaaacgaatt cgcatcatgc
     9241 gataaaggag gaagagcccc gtggcagaaa aggaaacttt ttatatcact acgccaatct
     9301 attatccaag cggcaaactt catatcggca actcgtatac tacgattgca tgtgacgcaa
     9361 ttgctcgtta taaacggttg atgggctttg atgtgtttta tctcactgga gtggatgaac
     9421 atggtcaaaa aatcgaaaca aaagcagaag aactaggtgt aaaaccgcaa gaatatgtag
     9481 ataaaatggc ggctgatgtc aagaaattat ggaaaacgct tgatatcagt tatgataaat
     9541 tcattcgcac gacagatgat taccataaag cagctgttca aaaaatattt gatcgtttat
     9601 tagaacaggg agatatttac ttaggtgaat atgaaggctg gtactctgtt tctgacgaag
     9661 aattctttac agaaacacaa cttgcagaag tgtacaaaga tgacgaaggt aacgtgatcg
     9721 gtggtaaagc gccaagtgga cacgaagtag aattggtaaa agaagaatca tacttcttcc
     9781 gcatgagcaa atacgcagac cgtctattgg aatactatga agaacatccc gaattcatcc
     9841 agccagaatc tcgtaaaaac gaaatgatca acaactttat caaaccagga ttagaggatc
     9901 ttgcagtttc acgaacaact tttacttggg gagtaccagt caagagtgat ccgaaacatg
     9961 tggtgtatgt atggatcgat gcattatcca attatattac tgcactagga tatggctccg
    10021 aagatgaaag tctattcgaa aaatactggc ctgcagatgt tcagatggtc ggtaaagaaa
    10081 tcgttcgctt tcatacgatc tattggccaa tcatgctgat ggcccttgat ttgcctctac
    10141 ctaaaaaagt atttgggcat ggctggctat tgatgaaaga cggaaaaatg tctaaatcaa
    10201 aaggaaatgt cgtttatcct gaaatgcttg tggaacgtta tggtttagat gcactccgtt
    10261 attatttgct tcgtgctgtt ccgtttgggt cagatggtgt ctttacgcca gaagattttg
    10321 tttcccgtgt caattatgat ctggcaaatg atctagggaa cttattgaat cgaacgattg
    10381 ctatgatcaa caaatattgt gatggactcg ttcctgacta tgcctcactt gtcactccat
    10441 ttgatagtga actgtctacg acggctgcta acgttgtcgg acgttaccat gatgcaatgg
    10501 aaaaaatgga attcaataca gcattggctg aaatctgggt gctgatttct cgtgcaaaca
    10561 aatacattga tgaaacagaa ccatgggtat tagcaaaaga cgaagaaaag aaagctgaat
    10621 tgaatagtgt catgatccat ttagctgaat ctttgcgtat cgcagcgata ttacttcagc
    10681 caatcatgac agaaacgcca gagaagatct tcaatcaact aggattggac tctgaaacaa
    10741 tgaatcttga aggattacac tttggcgaat ttccttcagg aacaaaagta gttgcaaaag
    10801 gtacaccaat cttcccacgt ttagatatgg aagaagaagt tgcttttatt caagaaaaaa
    10861 tgtctgaagg tactcaaaca aacgaagata cagtcaaatg ggatccagaa gaaacagaac
    10921 ttgtttcaac gaaagaaaaa caaatcaaat ttgatgtatt tgaaaaagta gaactaaaag
    10981 tagcagaagt catcaactgt caaaaagtag aaggggcaga taagttgctg caattccgac
    11041 tagatgctgg agacagccaa gaccgtcaaa tcttgtcagg aatcgctgaa ttttatcctg
    11101 atccaagcga attgatcggg aaaaaagtcg tcattgtagc aaatctgaaa ccacgaaaga
    11161 tgcgtggaca aatcagtcaa ggaatgatcc tttctgcaga agcaccagat ggctctttac
    11221 aagtaatcga agcaccaaaa tccatgccaa atggctcaga aatcgcatag aaattcaaag
    11281 ggggtatgac actagttgtg tcataccccc tttttccgaa atttgagaag caattttcgt
    11341 aaattccttc ttattacttg aagccaatca tataatacag aaacagagaa ctatccaaaa
    11401 taaatcctag aaaaagaagt acgagcttcg ctgatttttg ttaatttaga ataatactaa
    11461 taggaatcgt aaaaacagaa aaaaagcata atgataaagg gtcgggcaga ttttaattga
    11521 ttcatctggt actctttttt attgtcctta cattcataaa gtttgaatgc aatgacttta
    11581 ttacatctat atttatatct aacagtagcg ttgatgtgtt aattataagt tctatcactt
    11641 tatgttcaat tagtttgtgc tcttatatgt gtgattgaaa atatagataa aaaaacaatc
    11701 atcggctttg acttcgatga ttgttttctt tattttgtaa aaatcctatc acttgatttt
    11761 atggtaacct tttatttttg tcttcaaacg gcttggtaag agagcagtaa gcagtgcaaa
    11821 tgggatcgaa aagacatacc agaaaatcgt acgtccgata ccataatgtt gatagagctt
    11881 tgtcaacatc acgtgtaaca agatcaaccc taaaagcaag gagccagcta taaaccaatg
    11941 attatcccaa tgcatgactt cactaagtgc catcactcca aaaggataga aataaaaata
    12001 gatcccgact aaggtcatcc gccagttctt tgtaaatgtt ccgatattca ataaaaagaa
    12061 aatcgctgaa agcaaaatac cgataggcgg aaaaagccca accaaaaagg aatacaacat
    12121 cccccacaag atcatcacag gacctttgat caatgcaacg attgcgatga acaaagtcag
    12181 caatattagt ttttgtgata acgttgcaac agtcattaat ccaaataaaa ttaatgtgaa
    12241 ccaatgccaa tgggactgct gttgttcttt acgggaaaaa tcgacccggt tggataaata
    12301 atctgctaat ttcggataag aacgcttaaa atccataaac tgttcctcct tcgtggaaaa
    12361 ggtaggttta gtatacgaaa aataaaaaag aaatacatcc gtcttaagag ggagtttttc
    12421 actgaaagtg gagaaaaaag aatggtaaat taaaatattc tcagttatac tgaaaattat
    12481 accaaatttc aaagaagaaa gaggatggga atgaaaggca aactaaaacg agaaatcaat
    12541 ctgtttggcg cattagctac cgttatggga accgtgatcg gtgcaggcgt cttcttcaaa
    12601 actgctgctg ttactgctag tactcagtct acaagtttga cattgctagc ttggcttttg
    12661 ggtggtttct taacgatctg tgctggattg acagtggctg aattagctac agcaatcccg
    12721 gaaactggtg gagctgtaaa atatattgaa gctgcgtatg gaaaattgcc cagcttttta
    12781 ttaggatggg cgcaaagctt gatttacttt cctgctaata ttgctgcatt atcgattatc
    12841 tttgcgacac aattgacgaa cttattacaa ttatctaccg attatctttt gttgattgca
    12901 gtgatcaccg ctgtttctgt gacagggttg aatttgttag ggacaaaagt cggtgcttct
    12961 gtacaatcag tgacgttgat tgttaaatta ataccaattg ctgtgattgt catatgggga
    13021 ttattgaccc caggacaagg aactgtccag ttatttccaa tcgaagctgg aaaagatgtt
    13081 acttttgtcg aaggattgag cagtgcgttg ttagcaacgt tgtttgctta tgacggctgg
    13141 ttaggtgtcg gtgcaatggc aggggaaatg aaacggccgg aaaaagattt gcctaaagca
    13201 attattcttg gtttgagttt tgtaacagtc gtttatctat tgatcaattt tgtttttttg
    13261 aaaactttgc cgattgatca tcttgccggt aatttgaatg cagcttctga agcatcagac
    13321 gtcatttttg gaggaatcgg tggaaagctg gtcactattg ggatcttgat ctcggtatac
    13381 ggtgcattga acggttatac actaactggg atccgcgtgc cttatgcgat ggctttagaa
    13441 gacgagctac ctttcagtaa acagctgaca aagctttcaa agaagtttac ggttccttat
    13501 gttcctgcgg ttttccagtt agcagtagct tgtattatga tgagccttgg ttctttcgac
    13561 tttttaacag acatgttgat ttttgtgatg tggctattca gtttactgat ttttatcggt
    13621 gtctttattt taagaaaaaa agcgccggaa ttgccacgtc catataaagt accactttat
    13681 ccaatcgttc cgattattgc gattctcggt gctattttca ttttaggtat gacgatgatg
    13741 acgcaaacga aattagcatt gatcggtata ggtgttacct tgataggtat cccagtctat
    13801 tatcaaaaaa agaaaaaacg ctcagaagag taaaatattt caacaacaga cagaaaaagt
    13861 acgaactagg tcctctagat cttcgtgctt tttctatttc aataaaacaa gttcttctat
    13921 tttgattttt gctacttctg caagtagtgc ttatgtgcta aagtaagaat gaaaaggaga
    13981 gataaacatg atatttgatt ctcataccca tttaaatgct gaacagttca atgaagatat
    14041 tccagaaacg attcagcgag cacaagaaat gggggtaacg aaaatggcgg tcgtgggctt
    14101 cgatacgcca acgattgaaa agtctttgca attaagccat gactatccaa atatatacag
    14161 tattatcggc tggcatccga cagaggctgg cagttatacg aaagaaatcg aaaataaatt
    14221 acaagaacaa ttgactttac caaaggttgt agcattaggg gaaattggct tggattatca
    14281 ttggatggaa gacccgaaag aagtccaaga taaagtattt cgcagacaga ttgctatcgc
    14341 aaaagaaatg aacctaccaa tcagtattca tactagagaa gcacttgaag acacgtatca
    14401 aatcctaaaa gaagaagatg ttcgagatat cggtggaatc atgcatagtt tcagtggtga
    14461 ttatgaatgg gcaaaacgat ttcttgactt agggatgcat atttcattta gcggtgtcgt
    14521 cactttcaaa aaagcattag acgtccaaga ggctgcagca aatgtaccaa tcgaacgatt
    14581 acttgtggaa acagatgccc cttatctggc accagttcct tttagaggaa agcgaaatga
    14641 accaggctat actcgttata cagtagaaaa gattgctgaa cttcggaatc ttccgacaga
    14701 agaagtggct gcccaaacat ggacaaatgc gcaccgatta tttggtctaa gcgaacatgg
    14761 ataagatgaa gatccaagag attatagtcg ttgaaggaaa agacgataca agaaggctgc
    14821 gggaagtagt tgatgcagat acgatagaaa caatagggtc tgcaatcaat gaagagatcc
    14881 tgatgcaaat tgaacatgcc caagagactc gtggagtgat cgtttttacc gatcctgatt
    14941 tttcaggaga aaaaataaga aaaatcatta tggaagctgt tcctcaggca aaacatgctt
    15001 ttttgccgcg cacacaagct aaaccaaaga aaaagggaag ccttggtgtc gagcatgcaa
    15061 gtgatgctgc tattttagaa gcattgaaaa aggtcgtgac gccagacatt tcccaaacgg
    15121 ctgtttctga aatcactaga caagaccttt tagactatgg tttaatagct ggggcacaag
    15181 caaaagaaaa acgagaaaaa ctaggtgacg agttgcgcat cggttacacg aacggcaaac
    15241 aattggaaaa acgtttgaag atgtttcgta ttacgccgaa agaactcgcc caagcaatga
    15301 aaatagtgga ggaacaacat gagtgaatat cgtgaaattg cgacaccctc tagaacaaaa
    15361 gagattttat tgaaacatgg tttttcattt aaaaaaagtt taggacaaaa ttttctgact
    15421 gaaccaaata ttttaaggaa aatcgtagaa actgcgcaaa tagatgaaca tacgaacgtg
    15481 atcgaagttg gaccaggaat cggtgcattg acggaacaat tagccaagca tgcaaaacaa
    15541 gtcgtagcat ttgagatcga tgatcgtttg atccctgtat tggctgatac gatgcaaccc
    15601 tatgacaatg tgactattgt acatcaagat attttaaaga ccgatttgtc aacagctgtt
    15661 agagaaacat ttcatgagga gcttccgtta aaagtcgtag cgaatttacc ttactatatt
    15721 acgacaccga tcatgatgca ttttcttgaa tcagatttgg ttgtggatga actagtcgtc
    15781 atgatgcaaa aagaagtagc tgatcgtatc tctgctgaac caggaacgaa agcttatggt
    15841 tcattatcga ttgctgttca atattatatg gaagccagtt tagcattcat cgtaccaaaa
    15901 acagtatttg tccctcagcc aaatgtagat tcagcgattt tgaaactgac aagaagagat
    15961 ataccggcag tcgaagtgac agacgaaaaa gcatttttcc gattgacaaa agcggcattt
    16021 cagcaaagaa gaaaaacgct ttggaataac ttgcagcatt cgtatggcaa agatgaccag
    16081 acaaaagcat ggttagcaaa aagcttggaa acagctggaa tcgatccaaa acgtcgtggg
    16141 gagactttgt cattacaaga attcgccgca ttaagcaatg cgatgtcaga aaatatgcag
    16201 taaaaaaaga ggttgtgaca gaagttgtga aaaagctgtc ctgcatcaag taataagaac
    16261 agccaaacaa aaatagttcc tcatgttttt cgtttgtttg ggcttattac cgcagatgca
    16321 agcttttgaa caccgtttaa gaaagaggtt gtgggcctgc cgtttaactc taagtcacaa
    16381 ggaacaattt caaaaaacag cttctcatgt ttttgagtta gttggtctta ttacttgatg
    16441 caagcttttg accactatta tgccgaacaa ggagatgtga cacaaatttt gtcacatctc
    16501 ctatttttgt ttcttgatca aaaaattctt atacttgata ctcacactca ttttgtatgg
    16561 atttagaaaa gaatatgtgt cttgacagtt attagtaagt gagttatact aagtcgacat
    16621 ttatgtgtca agacatatta ggagagagaa aaaatgagaa aaaattcagt tcgaaaacta
    16681 acgatttctg ctttattgat tgggatgggg gtcattatcc caatggtcat gcctaaaatc
    16741 atgattccac cagcttcctt tactttggcg tctcatgtgc cattatttat tgcgatgttt
    16801 tttacaccag gagttgcagt ggctgttgcg ctaggtacga catttggttt ctttttaaca
    16861 acgccggtta tcatcgcatt gcgagcattg tcacatcttg tgtttgcgtt gattggggct
    16921 tggtacttgc aaaagcatcc gagtatcgtt ttaaaaaatg gacagtttac ttttgctaat
    16981 tggcgtttcc aagggttcaa ttttgtgatc ggtgtgattc attctttagc agaaatgcta
    17041 gtagtcagca tcttttactt tattggtaat atgcctgaaa catattattc tcaaggatat
    17101 ttttatacag tattcatctt gatggggatt ggtgggctta tccacagttt agttgattat
    17161 aatattgctt attttatagc aggaacactc agcaaatatt ttgatatccc cgtatttacg
    17221 gcagcaaaaa aagaaaatcg gaaagagtcg attcaagggt acgcgaagaa aacgacatat
    17281 tagacatgat ctctcaaaaa aaaaactctc atctagtaat ggataataaa tcctctaaga
    17341 tgagagtttt ttgtcctaaa aagagctgca ccaacatctt ctggcacagc tctaacaggg
    17401 ggcaatttat ggaagtttga tgacttgttc tgtttcttta tcaaagaagt ggcctttgct
    17461 gatgttgaag gcaaggtcga ctatttcgcc tggtttatgg aaatctcttg catctacttt
    17521 tgagatgaac tcagtagaac cagtttttgt gtaaagcatc gtttcagctc caagtaattc
    17581 ggaaacgaca acttctgatt tcactacggc ttcaggtgaa gcttcaaggg ctacttgttc
    17641 actgtggatg tcttctggac gaataccgaa gataacttct tttccttcat aacctttttc
    17701 aactaatact ttgttttttc cttcaggaat acgaagctta agcccatgtc catctgtgat
    17761 aacaccattt ttcaatgtca cattaaagaa gttcatggca ggagatccaa taaagccggc
    17821 aacgaacata ttgacgggtg tatcataaac ttctttcggt gtaccgattt gttggataaa
    17881 tccgtctttc atgataacga ttcggtcagc catagtcatt gcttctgtct gatcgtgagt
    17941 aacatagatg gtcgttgttt caagacgctg gtgaagtttg gcaatctcag cacgcatggc
    18001 tacacgtaat ttagcatcta aatttgataa tggctcatcc attaagaaga cttttgcatc
    18061 ccgaacgatt gcccgtccca atgccacacg ttggcgttgt ccaccagata aagcagctgg
    18121 ttttcgtttc aagtattctg tcagacctaa gatctctgct gcattgtcca cacgtttttt
    18181 gatgtctgct ttatcatatt tacgtaattt caagccaaaa gccatattat caaaaacagt
    18241 catatgagga tacaatgcgt agttttggaa aaccatggca atatcacggt ctttaggtgc
    18301 cacgtcattc atgacttttc cgccgatatt tagttctcct tcagagatat cttccagtcc
    18361 cgcgatcatt cgcaaagtag ttgactttcc acaaccggaa ggaccaacaa aaacgataaa
    18421 ttcacggtct ttgattgata gattaaaatc agttacagaa taattttctg cattgtcata
    18481 ttttttatat acgtttttca gagccatttc taccataata cgttccacac tttctttttt
    18541 agttttatta actatttaaa gtataaatga aagcgttaac taacttcaat gtcatgttga
    18601 acaagaattt tttctttttt ttgtcaatgt gctagtttta agctttaata aatatccata
    18661 agaaataaaa actgatacac tggagtaaat aagtatgtta acaatatcaa aaggagtgtc
    18721 tcttatgaaa atcgctttga tcgctcatga ccgaaaaaaa cctatgatgg tgaaattagc
    18781 aacagcgtat aaaacaatat tggaaaaaca tgaacttttt gctaccggga cgactgggca
    18841 gaggatcacg gaagcaaccg gcttgccgat ccatcggttt aaatccggac cgttaggcgg
    18901 ggatcagcaa attggagcca tgatttcgga ggatcagtta gatttggtga tttttcttcg
    18961 agacccgctg gctgcacagc cccatgaacc agatgtaaca gcacttatcc gtttatctga
    19021 tgtctatgag attccgttag ctacgaatat cggaacagct gaggtgctac taagaggact
    19081 ggaagccggc ttcctagatt ttcgaagaat cgtccatgaa atagacaagc atccactttc
    19141 attttgatgg ataagcgtat ggaaaaataa cgtttaatgt tcgcctatat gtagctataa
    19201 aagctaaaca aactgataat atgcgatata atacgaacgt attggataat ataaacaata
    19261 atattagttt ttcgtatttg cagtaaatgt gaaaatatgc tatagtttct gtgggaaaag
    19321 atcccaaaaa taatacagag tagaaaataa agcgttaagt gctaagagga tgggatgttg
    19381 cctcttggac gaaggacgta atgttcgcgg ttttattttc gcattcgctg catgatacga
    19441 tgtagcagct cttaaaggag atgctaaaaa tgaagaaaca ccggttagac gcacgtatga
    19501 ttgctattat gggcttattg attgcattga tggtcacttt gtcccgactg gtagcaatcg
    19561 agaccccatt tattaaaatc agtgtcacat ttattccaca agtgatcatg ggcattcttt
    19621 ttggtccttt ttggtcaggg ataggcgcag ttttagctga tttagtagga atggccctct
    19681 tctcgaaatc tgcattcttt attggattta cattgaatgc atttattgaa ggagcaatct
    19741 acggattctt tttctatcga aaagagatca cttggaaaaa tgccattctg gctacgctta
    19801 gtgtcacgct gatcatcaac ttatttttga caccattatg gcttgcgttg atgtaccatg
    19861 tgccattgtt cagctgggtc gtttgggcgc cccgcctgtt aaaaacagta atatggttac
    19921 cgattcaatc aattgccatt tattacgtag gacgtagtat tccttacaaa aaaattttaa
    19981 gaagtttagc gatccacgct aaataaaaaa caagcagtct tcccatccca gaagactgct
    20041 tgtttttatt gtgctgtgaa ttgtgcttga tagagccgtc ggtaataacc atctttttga
    20101 agcagctcat catgggtgcc catttcgaca atagctccct gatccatcac taatatctgg
    20161 tccgcatttt tgattgtgga caggcgatgg gcaatcacaa aactggtttt tccttccatc
    20221 attgctaaga aggcttgttg gatttttttc tctgtcaatg tatcgactga gctggtagct
    20281 tcatctaaga tcaacatagg gggattactg atcatcgttc gagcaatcgt caacagttgg
    20341 cgttgtccat ctgatatctt taacccttga ccgccaatct tagtatctaa tttttccggc
    20401 aaacgttcta caaattcata catataagag gcttttaggg catcattgat ttctgcgtca
    20461 cttgcttccg gattcccaaa acgaagattt tctcgcaatg tactgtcaaa tagccaagta
    20521 tcttgtaaca ccattccaaa acttttacgt aatgtatcac gttggataga gcggatgtca
    20581 tggtcatcga ctgtaattgt tccttttgtt gtgtcataaa aacgcatcag caaattaaca
    20641 agtgtggatt ttccggcccc tgtttttcct actatagcaa tggtttgacc tggataagca
    20701 gtaaaattga aatcttcgat caaacgctgc ttggggtcat aagaaaaaga aacatgatca
    20761 aaagagactt ttcctttgat atttttgggt tccaaggcat aggcatctgg caaatcaggc
    20821 ttttcttctg gctgatcgat caaatcaaat gctcgttcta gaccagaaaa agcggtttgc
    20881 agttgtgtcg tgattccaga aagttcgata aatggtttag aaaactgact tgagtagatc
    20941 gtaaagctgg aaatcacacc aacagtgatt gacgaaccac tcttcaatgc caataggccg
    21001 ccaactaaac caatcgataa ataagcaagg tgatctacaa aacgagaaga cgggtttgtc
    21061 aaggaagaag aaaattgtgc ccgttgtcct ttttcatata gatcagcatt tagcagttca
    21121 aattgctgtt gactagcttc ttcttgctga aaagctttca cgattttctg gttaccgatt
    21181 cgttcggtca caaagcccga gatatcccca ataatccttt gctgtctatc gaaatttgtt
    21241 tgtgaagcac gagcaacgat ccaactcaca aggaaaataa ttggtgtaga acaaagaacg
    21301 accaatgtca gaagtggact tagacgcatc ataaaaataa acgaaagaat gatgattgcc
    21361 actccagaaa ataattgatt gaaggccgca gaaattgcaa tggaaatatt gtccatatca
    21421 tttgtaaatc gactgacgat atttccgtgg gagttttgat cataataacg aagtggcaat
    21481 cgattcagat gagcaaatgc atcttttctt aattttgcaa cggataagta agctaaccga
    21541 ttgcttaaca cttggatgag ccattgactg actacgttga ttaaaacgat accaccgaat
    21601 agaataagta aatggaacag tcgattgaag cggacctgtc cttctccaat catttgatcg
    21661 atactttgac caatttgtaa cgtcatcaca actgttgcaa tcccattgat gattcctagt
    21721 atcacagcta gccaaatgtc ttttgcatag gcagtaaggt aaggaatgaa tcggcggagc
    21781 gtctgcaagg ataatttttt tactttcata actattcttc ctcctgtgat gcgacgattt
    21841 cctgatattc tgctgattga gcaagtaatt cttcatgggt accctgagca gcaatcttac
    21901 cttgatccat cactaagata tgatgtgctt cttgaataga gcggacacgt tgggagataa
    21961 taatcactgt actgccaaga taagtctgta gcgccttacg caaatccaag tctgtttgat
    22021 aatccaacgc acttaaagag tcatctaaaa tcagtaatgc tggcttggca atcaaagctc
    22081 ttgcaatcgt cagtcgctgt ttttgtccgc cagagaaatt tttcccattt tccatgactt
    22141 ttgtatctaa accatttgga agctgacgga caaattcttc tgcctgagcg attttcagag
    22201 cttcccaaca ttctttttct gtggcgtctt tcttacccca ttgaaggttt tcacgaatag
    22261 tcccggtaaa tagtacagaa gtttggggaa caagagcaat ttgctgacgg agatgatcca
    22321 gctgccaaga acgaacatcc attccgtcca ttataactgt accggaactg acatcataga
    22381 aacgcggaat caattgtgtc aaagtcgttt tcccgcttcc ggttggacca atgattccaa
    22441 ggactgtatt tcgcttcagc tgaaatgtaa tattttggag agaaagacca gaatcaggag
    22501 tataacggaa gtcaacatgg tcaaaagcga taattgcttc agaagaaaaa tcgggagtag
    22561 tactgacctc agcttcaaga atcgaatttt ctgtgtctag cacctctttc acccgatttc
    22621 ctgaagcttc ggcacgtgtg aagatcacga cgaggtttga aacaacgatc agtgccaaaa
    22681 gcatttgatt catataattg atcaaagcaa gaacttgtcc ttgttgcaag ctaccaatat
    22741 ttactttgat cccgccaact gtcagcaaac agatgatccc gacattcatg atcaaggttg
    22801 tagcaggtga taatagggca gagatattgg aaacacgtaa ataattgttc gctagatcat
    22861 ttgtgctttt atcgaacttc tctgtttctt tttttgtctg cgcaaatgcg cggatgacac
    22921 gaacaccgct aagattctga ctaacgtgtt cattgagctg atctagtttt tcttgcactt
    22981 tttggtagag aggaacggtt tttttgatga taaaaaataa aatgattgag aaaataggca
    23041 ataatgctaa gaaaaacaga cctacttccc agtcgatcac aaaagccatg accactgacc
    23101 cgatacttaa aaacggtgct ctgatcaata aacgaatgac cattgctaaa gctagctgaa
    23161 gctgattgat gtcgtttgtc attcgggtga tcaaggtatc tgttccaaaa tgattcaact
    23221 cgttgtgaga gaaagtattg atttttttga ttagctgatt acgtaactct gtaccaaatc
    23281 cttgtgaagc tactgaagca tagtattggc aaatgatagc acaaatcaga ccaatcacag
    23341 acatagcgac catccataag cccatttcaa tgatttttcc tcggtcattc atttttagtc
    23401 cattatcgat caaggaagcc atcattaaag gcaggacaag ttcgaagaca gcttcaagaa
    23461 atttgaagaa cgggcccaaa atgatttgct tacgatagtc ttttgcataa cgtaataact
    23521 gaatcatatg attcctccta ttatttattt gtccacaatt gaaaaaacaa gtactaccac
    23581 attgtagctt aggaaattta gaatgaaaag agaacaagcc ttttcataaa tgaaagtttt
    23641 attatgaaga agctttagaa attgaataga ctattttttt taaaaaaaag aaaatgagaa
    23701 aacatgccag tctcttcatt cataggaacg tctattttac ttaatttttc tataaatgaa
    23761 ttctgcataa aaaatatatc aagtaaatgt ttatagatga aactctattt acttcttttt
    23821 taatttgttc ttgcaatctt ttttgctacg taatttttgt aaaaaagtgg gttgagagaa
    23881 atctaattga ttttcaaaga aggagtatga aaatgagaaa aatatttatt cgtttattgt
    23941 gggtactatc ttagaggaat aaataatagt ggagaaaact atggtttggc gcagattcta
    24001 tcaggtttga tggaacgaag acaacctccc gacatcaagt caaaagccac ttgagatttt
    24061 gatctgaaaa taaaaaaaga aaacaaggta ggaacatcaa tgtttctacc ttgttttcgt
    24121 aatcaatggg aaaaaactaa gagtggtgta cgtaatcaat aaaaaggatg gtgacaacag
    24181 tacctcttta ctctctgaaa gcatcataac tcgtttttcc tcattatgcc aataaattgt
    24241 tgttatacca catataagga tttgtaatag ctaaaaacag acaggaaagt tgaaatctgt
    24301 gaatcttatt ttgtatggaa ggatttatag aacgcaaaaa tcaagataaa gatgaataaa
    24361 aatcctgttt cggctatata ttgcgtatct acgccaataa aacgagtttg ttctgtcata
    24421 gccatataaa gcaaaggcaa aaatacaact acagcgagat aagatccgat gatttctcga
    24481 aaagttttcc aggaagtatg tttcctgttt ttatatttat ccgatttcat tgaatagtca
    24541 tagcctcctt attctttcat atgttgaaat tccagtataa aaactggaag gaactgtacg
    24601 ttttttagaa taaaaattat aagggataag taggctgctg tctataataa gatatatttt
    24661 tcaattcttt attaaagatt ttattgacaa aatgaatccg ttttctatga tggaggaggg
    24721 gtgaataagt tgttgaagaa ggaaatttta tgttacttag agaaccagac agcctttttc
    24781 gatttagaac atatgaacga ggtctttaca gcacaaaggt tagctgatca ttttggggta
    24841 aaaagaaaca cagtcagtca ttatttgaac cagttaaatg atgagcaact actagtcaaa
    24901 atcaattctc gaccagtgat ttatttccac aaagaagctt ttgaaaaaca attttttaag
    24961 ttacgcacga atttttattt ttctatcgat gatctcaaag aggaacagcc ttttttcgcg
    25021 caaccaaaag acttattctc ttttatgatc ggatacgacg ccagtttgaa agaaagtatc
    25081 gaacaaatca aaacagctct ttactatcca gatggcggat taccactttt gattacaggc
    25141 gaaagtggca caggtaaaag ttatttagtt aatttggtct atcagtattg tctgcttcat
    25201 gatctgctag aagattctgc accattcatc acttttaatt gtgcacaata tgcagataat
    25261 cctgaacttt tgactagcaa tttgtttgga catgttaagg gagcgtacac tggtgcagaa
    25321 gaaaataaaa aaggggcttt tgaagcagca gatggtggga tcttgttttt agacgaggta
    25381 catcgcttaa caccagaagg tcaggaaaaa ctgttcacct atcttgatca aggtgtgatt
    25441 tatcgtatgg gagaacctaa tttgtcacgc cggatcaaaa cacgtctctt ttttgctacg
    25501 actgaagaga ttactagtca tttcttaaca actttcattc gaagaatacc tatccgaatc
    25561 gaactacctg cacttaatca gcgtagtcgt aatgaacggc tagaactgat ttactctttt
    25621 tttctcgaag aacaaagaaa aatggggagc cctttgtcag tcagtggacc agctttgtca
    25681 cttttaacaa gtcagaaatt atccggaaac ataggagagc tgaaaaatat cgtcaaagtt
    25741 tcagcagcaa aagcatatgc tgaacagcgt gaacagcctg aaatccatgt cacgatccat
    25801 catttgcaaa aagaactact tgcgcagcct attactaaaa atacagcaca gcaaggaatc
    25861 tatattacgc aagaccagac cttagagcaa ttaatggaga agcaacagcc cgaacagcag
    25921 cgaatcgtta aaagttttga gcaaatccta attgatttca agaaaaataa ctgtctgcta
    25981 tattcttgcg aaggaaaatt aaagcaagaa gtgattcaat tatttgattt tttgctgttt
    26041 gagaccagta gacaagaaaa acacgagctg ctggtttatt ggacacaatc tatccgagag
    26101 acctttcgac aaatggaaac tgcctatcaa atcaaattcg atggaaacag tgtctatgcc
    26161 ttgagttact atctctatca gcgaagcact atcaaatggt taccggaaga acatgatatt
    26221 atccaactaa tcaaagaatt agaacaacaa gtttctcagt cttatccatc tagttatcac
    26281 tatgtccaac gaattctgga attaagtaag atcaaattag atattgaaga cacaagtatg
    26341 gatcggattt tactgacgat ctatctaaaa aaagcgaaat ggtcaaaaga aaaacgactg
    26401 ccaaaagcga tgattgctgc tcacggttat gcaactgcta gcagtatggc aaatgtagta
    26461 aatcgtttat tacaagagga tctatttgaa tcatttgata tgccactaga tgtcacacca
    26521 cagcagattg cttcagaaat ccttgattat tgcgaaaaca gcgatgtttc aaatggattg
    26581 atcatattag tagacatggg atctctgaaa gaaatccatc agttttttaa aaaacagtta
    26641 tccgtaccgc ttttgatttt gaataatgtg acgacacctt tagcaatcac agtaggggaa
    26701 tgcctgcaaa aaaatgtatc attagaagag atagcagaag agactgttcg acagatccag
    26761 ccagaatggc gactgctcta tccagaggaa aacaaaccca aagcactcat tactacttgc
    26821 ttcactggaa tcggtacggc ggtccactta agtgaactgc tagaaaaaag cttacctacg
    26881 gcttgtcagt tgaaaatcat cccatatgaa tatcagcaat taaaagataa gaaaaacagt
    26941 gacccattat tttccatata cgaagtcgta ggaatgattg gcaccacaga tcctgatatc
    27001 accaatatcg actatctttc attagaagac ctcatctcgg gggaaaagat gtctgtacta
    27061 gctgaatggt tggacactac tatgaatgct tcagagaagg aaatattcaa tcagcgcatc
    27121 attcgtaatt tttcattgga aaaagtactg gattccgtga ctattctaga tacagagaag
    27181 gtgatgggag aaatcgatca ttttatgaga gaattagagg tgcagttgaa tcgaagcatc
    27241 agcaatccca aaaaattagc gttgtatgtc catgtgagct gtctcattga acgattgatc
    27301 cgacaaatgc caatcgaaac ctatcaagga ttagagaaat ggaagcagtg tcaaaaagaa
    27361 gggttatctg ctattaaatc tgcgtttagt gtcattgaag agcattatag tgtcatgatc
    27421 cccaattctg agattgccta tatctatgat attttgagtg aagatacaga gtttctctcg
    27481 atagaagaag aattttgaac ataagcaagt tgttgccact aattttggca tgcaacttgc
    27541 ttttttagta tgtgtaagtg aaaagaggag atgaaaaagt ggatagagaa attatcttag
    27601 cttcccatgg aaaatttgct tcagggatat tagattcatt agagctgatc tatgggaaaa
    27661 atcattctat tactgtattc gattgctata ctgatgagaa ttttgattta gcggaaacag
    27721 taaggcagct ttttatgagg tacaaagata aagaaatcat tgttctgacg gatctttttg
    27781 gcggaagtgt caacaacgaa ttcttacaat atatcaatcg ggatcatgtc tatctcgttg
    27841 ccggattgaa tttgccacta ttgattgagc tagtatctcg gttggacgct gaagtagaga
    27901 caactgtttt gatccagcag gtgctaactg attcaaaaaa aatgatccag ttttgtaacg
    27961 agcggctcaa tcagaaaata gaagaagacg aattttagga ggaagaaaaa tgattgtatt
    28021 gacaagagtc gaccatcggt tattacacgg acaagtagct ttttcatgga cacaaacaat
    28081 aggcgcagac tgtattttga ttgctaatga tgatgtacct acgaatgaga tacgaaagac
    28141 aacgatcaaa ttagccaagc cacaaggagt caaactagtg atcaaatcaa ttgatgactc
    28201 gattgccgcg ttgaaaagcg gggtgacaga taaatataag ttattcatcg tagtggaatc
    28261 gatcgaggat gcatataagc tggcagaagc gtatccagaa atcaaaacca tcaacttagg
    28321 agggatcaag gcaaaacctg gtactcgcag catcggaaaa gcggtaaata ttttaccaga
    28381 agaggaggaa cgcttgaaac gattaattga caaacaaata gaagtagaaa tccgtcaagt
    28441 accagcagat aaaaaagtgg atgtaagaga agttttgtaa gaaaggaaga acctcaatga
    28501 ttgtacaagc agtcttatta ggaattgttg catttgtcgc acaatcagaa tatgcactag
    28561 ggacatcgtt gctttctcgt ccgattgtga cggggctgtt tacaggaatc gtgttaggtg
    28621 atgtaaaaac tgggatcatt atgggcgcaa ctttagagtt agcatttatc ggatcgttct
    28681 cagtaggtgc ttcgattcca cctgatgttg tgaccggtgg gattttaggg acggcttttg
    28741 ctattacagc tggagccggt acagaaaccg cgcttttact aggtttgccg attgctacgt
    28801 tgacattgat attgaaaaat atttacttag ggcttttgat tccaattatg aaccataaag
    28861 cagacaatta tgcagaagaa ggaaattata aaggagtcga gcatatgcac ttgcttgccg
    28921 gtatcggtct ttccttgatg cttggtgttg tggtaatggt ttcttatatg gtgggaagca
    28981 atacgatcgg aaatctatta aatatgattc ctgacttcgt tcaaaagggg ttgtcagtag
    29041 ctacagggtt gattccagct cttggttttg cgatgcttgc tcgtttgctg atcaacaaac
    29101 aagttgcacc atattttttc ttaggttttg ctatagcttc ttacttagag attcctgtga
    29161 ccggagtagc tatttttggt gcgattttag cagttgtggt agtcaatatt atgaatgtcc
    29221 gtcaactacc acttcaaaca actgcagggg aggtagaaga agatgaagaa ttctgagatc
    29281 aaaaacagca aaataacgaa aaaagagcta aatcacgtat tttggcgttc ttttcaaatg
    29341 gagttttctt ggaattatga acgtcagatg aatatggctt atgtttatgc aatgattccg
    29401 attttgaaaa agttatatca gtcgaaagaa gaaatggcag cagctttgaa acggcatcta
    29461 gagtttttta acacgacccc acatatcgtt acactgattt taggaatcac ggctgcaatg
    29521 gaggaagaaa ataaggatga tcctgaattt gatgtgactg cgatcgatag tatcaaaaca
    29581 tctttgatgg gacctcttgc agggttagga gattctttct tttggggaac tttgcgattg
    29641 attgccacag gtgtgggtac ctctttagcc atgcaaggaa atattttagg ccctatcttg
    29701 ttcattttga ttttcaatat tccgcacatt ctgtttcgct atctagcaac aggttgggga
    29761 tatcgcttag gaacgggttt tttgaaaaag atccaggcaa acggtatgat ggaaagtttg
    29821 acattaggcg cgtctattat tggactgatg gtcgttggag caatgactgc cacgatgatc
    29881 accatcaata ttcctttaaa aatcggttca ggagaaaatg ctgtgactgt tcaaagtatt
    29941 tttgatgata tcgttccaaa tatcttatgt cttggagcat ttggcatagt gttttatcta
    30001 ttgaagaaag aagtgaaacc attaacgatc ttgatcggac tagctttctt tggaattttt
    30061 ggttcgtgga tagggatttt ttaaaaaagg agcagagaaa atgtttacga tgcaagatta
    30121 tatctatgaa gaaaaggaag tactaagtac gatcttgaaa aagaatgatt tttcgacaag
    30181 agaacatatg aaaaaaacag tgaatttact gatcttagca acgggttcat cttataacgc
    30241 ttgtttagca gcgaagccag cattggaatc ttatggtgat cttactgtcg atattcaaga
    30301 acctttttat tttttcaatt atggaaaact ttctccttca atcgatactg tgattgctgt
    30361 gtcacaaagc gggaaaagtg cttctactgt tgaagcagta aaaatgatac aaaaacaagg
    30421 gttacctgtt gttgctatca caaatgacgt gcaaagtcca cttgctttag aagctgcaca
    30481 aattattgat ttaggtgccg gggtagaatc agtaggcttc gttacaaaag gctattctgc
    30541 gactgtttta cagttactac tcttagggat aggaattgga ataagtaaaa ataaaatcag
    30601 caaaaaaata gaacaagact acatgcaaca gttgcgcaaa ataatcaacc atttaccagc
    30661 gattattcaa aaaacggaag aattttttga tggatatcaa agtttatttc gtttagcaca
    30721 gcgtttcgtc accattggat atggtccaaa ctggggaaca gctaaagaag cagagacgaa
    30781 attgactgaa acaatccgcg ttccgtcaca aggatttgag ttagaagctt atatgcacgg
    30841 cccatacctg gaggcagatg cttcgcattt gctattcttt attgaagggg aaagtgtaaa
    30901 taaggaacgt tcgcaaaagt tgcaaagata tatgagtcgg tacgttggag agactctcac
    30961 cattaccaca aaaaaagcaa gaaacgagaa aacacttgga ttagcaatag aatgtgatga
    31021 atatctgtct gtattagcgc ttgtcgttcc gtttcaacta ttcgcttata aaaccgcagt
    31081 agctaaaggt attgacttga acaaaaagat ttttgaagac tttgatacag tcttgaaaag
    31141 taaattataa gaggtggaaa tcatgctgaa attcaatgaa gaagaacaaa tcaaagcaat
    31201 aaaaggcgca ctagctttac gtccgcaagt agaagaaatc atcgataaac tttatgcgga
    31261 aaaatttgac gctgtctatt atctaggaat cggtggaacg tatgcttcct cgatgcaagc
    31321 tgtcacttat atgaatggga aaagcaactt gcctgtcttt gtacagcatg ctgcagaata
    31381 ttacactact ggaaacaaaa gattaacaaa agattctatc gttattttgt cctctgttac
    31441 cggtacaact caagaagtag tgaaagcagt agaacaaatc aagaaagtag gagcgacact
    31501 gattggattt atcgataaag cgaacagtaa gttgtctcag ctatgcgatt ttgtggtcac
    31561 ttatccagct cctggaacag aacaaatcaa attttttatg gcagcagatc gattgatgta
    31621 tttgaatgga gaattcgaag cttattcaga atactatgaa cagctcgaac gttatttacc
    31681 aacagggtta gtggaagcag agaaaaaagc agatgcattt ggcttatcat ttgcagaaaa
    31741 acatcgacgt gatagtatgc attattttat tggagcaggg aatcaatggg gagctgttta
    31801 ttcatatgcc atgtgttact gggaagaaca aagctggctt ccatcgaaat ctatccatgc
    31861 tgccgagttt cttcacggga cgttagagat cgtagaagaa acaaccccag tcacattatt
    31921 tttaggcgaa gatgaacaga gagtgttatc tgaacgtgtg gctaaacttt tgccaaaaat
    31981 ttgcagcaat tatacattga tagacacaaa agactatcca gtagaaggta tcagtgaaaa
    32041 atatcgcgga cgtgttttgt ctttcttatt gatgcatgta gtgacacaac gcatcgatgc
    32101 tcatgtggag cagttgaact gccatccatt agagatacgc cgctactatc gtcagtttga
    32161 ttattaggat agactggata aaaagaatat aaaaaataaa gagagcagcg ataactgctc
    32221 cctttatttt tttaaaatat tggcatcaat tacgttataa aacacatttt ttgcattatc
    32281 tacagttcaa cttataatct gtttaatggg acatgtgggt gccaaccatt ttttgttatg
    32341 caatagtact atttagttgt tgcatggatc cgtagtaaaa gtccaagtac aacgagttgc
    32401 gccagtttac atagcgtttt gtatccagaa tgttgactaa aacaaaagtt cctatgtcaa
    32461 ccgtcaacag agacaatctg tccgttgcag gacctgacag atttagaaat gttcaatctg
    32521 tctcttatgt attttaaatc aatactcact aggagaagtt tcctaacctc ctaatagtaa
    32581 tgctggtagt aacattgtca aaactgcttc ctcttaggaa caagcaaagc ataacgagtg
    32641 taaaaataaa atgtagacta ttgtaacata tcattgatta tttcaagtaa aaacgataaa
    32701 agaagtaaac aaacacttaa aaacaatgga aattagtccc aactttaaga aatgtatact
    32761 ataatggaaa ttatcaatta tttatttgga ggaatatcca tgaaacaaaa aatcgcagtt
    32821 cttggtcctg gatcttgggg cactgcttta gcacaaacat tggcagaaaa cgggcatgat
    32881 gtccgtattt ggggaaatgt acctgaacag attgatgaaa tcaataagta tcatacaaat
    32941 cagcattttt tacctgattt gacgatccca gaatcgatta tcggatataa agaattggca
    33001 gaagcagtgg ataacgcaga tgctatttta tttgttgttc caacaaaagc gattcgttca
    33061 gtcgcacagg aacttattgg taaaatgaat actaagccaa tcattataca tgcaagtaaa
    33121 ggactagaac aagatacgca taaacgaatc tcagaagttt tggctgaaga aattccagaa
    33181 gaaaaaagac aggcaattgt tgtattatct ggtcctagcc atgctgagga agtggcagta
    33241 catgatatca caacaattac agctgcaagt attgatcaaa aagcagcagc ctatgtacaa
    33301 aaactgttca tgaatgatta tttcaggatt tatacaaata atgatgtgat tggcgtagaa
    33361 actggtgcag cactgaaaaa tatcattgca attggtgccg gcgctatcca tggattagga
    33421 ttcggagatg atgcaaaagc agcaatcatg actcgaggat tggcagaaat cagccgtctt
    33481 ggtgtcgcga tgggtgccaa tcctctgaca tttatcggtt tgagtggtgt gggggacttg
    33541 atcgttactt gtacaagtgt tcattctcgc aattggcgtg ccggtaactt gttaggacag
    33601 ggacataagc tggaagaagt tctagaaaac atgggaatgg tcgttgaggg tgtggcaacg
    33661 acaaaagcag cagtagagct agctcaacag ctaggtgttg agatgccaat tactcaaaca
    33721 atctataatg ttttgtataa tggagaagat atcaaaaaag cagcaaaaga aatcatgtta
    33781 cgtgacggaa aaatggagaa tgaattttct cttcgttaaa tagatgatca atagttaatc
    33841 gt
//
LOCUS       DAZUJR010000025        33779 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.025, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000025 DAZUJR010000000
VERSION     DAZUJR010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33779
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.025"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(36..593)
                     /gene="frr"
                     /locus_tag="ACG804_001086"
     CDS             complement(36..593)
                     /gene="frr"
                     /locus_tag="ACG804_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HFS4832032.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(596..1318)
                     /gene="pyrH"
                     /locus_tag="ACG804_001087"
     CDS             complement(596..1318)
                     /gene="pyrH"
                     /locus_tag="ACG804_001087"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HFS4832033.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(1454..2335)
                     /gene="tsf"
                     /locus_tag="ACG804_001088"
     CDS             complement(1454..2335)
                     /gene="tsf"
                     /locus_tag="ACG804_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HFS4832034.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(2434..3216)
                     /gene="rpsB"
                     /locus_tag="ACG804_001089"
     CDS             complement(2434..3216)
                     /gene="rpsB"
                     /locus_tag="ACG804_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HFS4832035.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            3575..4054
                     /locus_tag="ACG804_001090"
     CDS             3575..4054
                     /locus_tag="ACG804_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFS4832036.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            4271..5362
                     /gene="phnW"
                     /locus_tag="ACG804_001091"
     CDS             4271..5362
                     /gene="phnW"
                     /locus_tag="ACG804_001091"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047304 - 2-aminoethylphosphonate-pyruvate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HFS4832037.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            5355..5483
                     /locus_tag="ACG804_001092"
     CDS             5355..5483
                     /locus_tag="ACG804_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HFS4832038.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            5487..6032
                     /locus_tag="ACG804_001093"
     CDS             5487..6032
                     /locus_tag="ACG804_001093"
                     /inference="COORDINATES: protein motif:HMM:NF024811.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase-like protein"
                     /protein_id="HFS4832039.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(6486..8177)
                     /gene="argS"
                     /locus_tag="ACG804_001094"
     CDS             complement(6486..8177)
                     /gene="argS"
                     /locus_tag="ACG804_001094"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HFS4832040.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(8597..9544)
                     /gene="arcC"
                     /locus_tag="ACG804_001095"
     CDS             complement(8597..9544)
                     /gene="arcC"
                     /locus_tag="ACG804_001095"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HFS4832041.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(9659..10678)
                     /gene="argF"
                     /locus_tag="ACG804_001096"
     CDS             complement(9659..10678)
                     /gene="argF"
                     /locus_tag="ACG804_001096"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HFS4832042.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(10769..11998)
                     /gene="arcA"
                     /locus_tag="ACG804_001097"
     CDS             complement(10769..11998)
                     /gene="arcA"
                     /locus_tag="ACG804_001097"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HFS4832043.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            12459..13160
                     /locus_tag="ACG804_001098"
     CDS             12459..13160
                     /locus_tag="ACG804_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFS4832044.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(13769..14785)
                     /gene="tsaD"
                     /locus_tag="ACG804_001099"
     CDS             complement(13769..14785)
                     /gene="tsaD"
                     /locus_tag="ACG804_001099"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HFS4832045.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALAAKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(14782..15246)
                     /gene="rimI"
                     /locus_tag="ACG804_001100"
     CDS             complement(14782..15246)
                     /gene="rimI"
                     /locus_tag="ACG804_001100"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFS4832046.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(15253..15795)
                     /gene="rimI"
                     /locus_tag="ACG804_001101"
     CDS             complement(15253..15795)
                     /gene="rimI"
                     /locus_tag="ACG804_001101"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFS4832047.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(15779..16501)
                     /gene="tsaB"
                     /locus_tag="ACG804_001102"
     CDS             complement(15779..16501)
                     /gene="tsaB"
                     /locus_tag="ACG804_001102"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HFS4832048.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(16692..17672)
                     /locus_tag="ACG804_001103"
     CDS             complement(16692..17672)
                     /locus_tag="ACG804_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4832049.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(17696..19180)
                     /gene="galT"
                     /locus_tag="ACG804_001104"
     CDS             complement(17696..19180)
                     /gene="galT"
                     /locus_tag="ACG804_001104"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0017103 - UTP:galactose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019388 - galactose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HFS4832050.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(19192..20181)
                     /gene="galE"
                     /locus_tag="ACG804_001105"
     CDS             complement(19192..20181)
                     /gene="galE"
                     /locus_tag="ACG804_001105"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HFS4832051.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            20429..20596
                     /locus_tag="ACG804_001106"
     CDS             20429..20596
                     /locus_tag="ACG804_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HFS4832052.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(20658..22469)
                     /locus_tag="ACG804_001107"
     CDS             complement(20658..22469)
                     /locus_tag="ACG804_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HFS4832053.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(22466..22831)
                     /locus_tag="ACG804_001108"
     CDS             complement(22466..22831)
                     /locus_tag="ACG804_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HFS4832054.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(22994..23389)
                     /locus_tag="ACG804_001109"
     CDS             complement(22994..23389)
                     /locus_tag="ACG804_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFS4832055.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(23407..24369)
                     /locus_tag="ACG804_001110"
     CDS             complement(23407..24369)
                     /locus_tag="ACG804_001110"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HFS4832056.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(24369..24581)
                     /locus_tag="ACG804_001111"
     CDS             complement(24369..24581)
                     /locus_tag="ACG804_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HFS4832057.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(24602..25300)
                     /locus_tag="ACG804_001112"
     CDS             complement(24602..25300)
                     /locus_tag="ACG804_001112"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HFS4832058.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(25320..25862)
                     /locus_tag="ACG804_001113"
     CDS             complement(25320..25862)
                     /locus_tag="ACG804_001113"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HFS4832059.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(25994..26998)
                     /locus_tag="ACG804_001114"
     CDS             complement(25994..26998)
                     /locus_tag="ACG804_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFS4832060.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(26995..27984)
                     /locus_tag="ACG804_001115"
     CDS             complement(26995..27984)
                     /locus_tag="ACG804_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFS4832061.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVEKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(27981..28787)
                     /locus_tag="ACG804_001116"
     CDS             complement(27981..28787)
                     /locus_tag="ACG804_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4832062.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            28953..29909
                     /locus_tag="ACG804_001117"
     CDS             28953..29909
                     /locus_tag="ACG804_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFS4832063.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(29986..30504)
                     /locus_tag="ACG804_001118"
     CDS             complement(29986..30504)
                     /locus_tag="ACG804_001118"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0005542 - folic acid binding [Evidence
                     IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HFS4832064.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(30592..30741)
                     /gene="rpmG"
                     /locus_tag="ACG804_001119"
     CDS             complement(30592..30741)
                     /gene="rpmG"
                     /locus_tag="ACG804_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFS4832065.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            30969..31415
                     /locus_tag="ACG804_001120"
     CDS             30969..31415
                     /locus_tag="ACG804_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HFS4832066.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(31610..33505)
                     /gene="asnB"
                     /locus_tag="ACG804_001121"
     CDS             complement(31610..33505)
                     /gene="asnB"
                     /locus_tag="ACG804_001121"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HFS4832067.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
BASE COUNT         9836 a         7096 c         5910 g        10937 t
ORIGIN      
        1 gcggaatgat ccgcccctct gtttttatga ttttattaaa cttccaataa ttctttttct
       61 ttatcagcag cgatcttatc tacttctttg atgctgttat ctgtcaatgt ttgtacgtct
      121 ttttctaatc cgcgcaaatc atcttcggta atatcaccat ttttttgttg ttttttatat
      181 tcatcgatcg catcacgacg gatgttacga atcgcgattt ttgcattttc tgcttctttt
      241 ttaacatctt tagctaattc ttttctgcgt tcttctgtca gttgcgggat aactaagcga
      301 atgacatttc catcattggt tggactgatt ccgatatcac ttgccataat agctttttca
      361 acatcttgaa gaatgctctt gtcaaaaggt gtgatcatta aaacacgtgc ttctggaatt
      421 tggattgatg ccatttggtt caatggtgtt ggcgcaccgt agtagttcac agtaatacgg
      481 tccaaaaggc tagcgttcgc acggcctgcg cggatttgcc caagttcacg ttgaagattt
      541 tgtgctgctt ttttcatttt ttcttttgct tctgtcataa ttgcatctgc catttttatt
      601 tcccccttac agttgttccg atattttcgc ctaagattgc acggcgaata tttccgtgtt
      661 catttaaatt gaagacaagc agtggaatat cattatccat gcttagtgaa cttgcagttg
      721 aatccatgac ttgtaatcct ttggcaataa cttccagatg agtcagttct tcaaatttta
      781 ctgcatttgc atctactttc ggatcagcag aataaacacc gtctacattg tttttagcca
      841 tcaggataac atctgcgccg atttctgccg cgcgtaatgc tgctgttgtg tctgtcgaga
      901 agtacgggtt gccggtaccg cctgcaaaga taacgatccg tcctttttct aaatgacgtt
      961 ctgctttacg gcgaatatat ggctctgcga tttgacgcat ttcaatcgaa gtttgcacgc
     1021 gtgtcggtac acccacgttt tccaacgtat cctgtaaagc taaggcattc ataactgtag
     1081 ctaacatacc catgtaatca gcttgagcac gttccatgcc catttgtgct ccgatttgtc
     1141 cgcgccagat atttccgccg cccacaacga ttgccatttc aacgcccagc tcgtgaactt
     1201 ctttgatttc ttggatgatt tctttgatta ctggtggttt gattccaaat cctgcgtccc
     1261 cagctaaagc ttctccactc aattttaaga ctacacgctg atatttcggt gtgaccatgt
     1321 tcattcctcc aatattttct attgccattt taccatactt agatgatttc gacactctaa
     1381 gactggtttt tcttgttttg cttaaaaaaa gggagcgcac aaaccgtgcg ttcccgtctg
     1441 ttattcaaca gaattatttt ttcacttggc tcataacttc ttctacaaag ttatcttcgc
     1501 gtttttcgat accttcgcca acttcgaaac gtacgaatgt tttaacagtt gcgccttttg
     1561 atgcaacgta tttttcaaca gtcatatcag gatctttaac gaatggttgg tccaccaaag
     1621 cgatttctgc tttgaatttc ttcaagcgtc cttctaccat tttttcaacg atattcgctg
     1681 gtttgccttc gttcaatgct tgttctgtaa gaacagtttt ttcatgttct aattcagctt
     1741 ctggaatttg tgattcgttt acataacgag gattgatagc tgctacgtgc atagctacgt
     1801 ctcttgcaac tgtttcgtca gttgttccat ctagaacagt caatacggca atacgtccgc
     1861 ccatatgcaa gtatccacca aatgcagcat tgtcgtcttt ttctacaact tcaaagcgac
     1921 ggaagctgat tttttctccg ataacttgag ttgcttcgat caagtcagat tcaattgtac
     1981 ctttatctgt tttgattttc attgcagctt ccatgtctgc tggtttgttt tcagcaacaa
     2041 gttctgcaat ttcttttact aaatcttgga acatttcgtt tttagaaaca aagtctgttt
     2101 ctgagtttac ttcaacgatt gctgcagtgt tacctttcac agcaactgaa gccaatcctt
     2161 cagctgcaat gcggtcattt ttcttcgcag cctttgccat tcctttttca cgtaaaagat
     2221 caactgcttt ttccatgtcg ccttctactt caactaatgc ttttttcgca tccatcattc
     2281 ctacgccagt catttcgcgt agttctttta ccattttagc tgtaacgtct gccatgttta
     2341 actcctcctg tgtgtttttc tttttaaaaa aagctgcttc aaaggagagt gaggcttgtc
     2401 gcccagcctt tgaaacagct ccatcattca aaattattct gctgaagaat tgtcgccttc
     2461 aacaacatct acgatttctt cgattgatgt tgctgtgttt tcttctgtga aatcttcttc
     2521 aactacttga tcttcacctt ggtttccttc gatgaaagca tcagccattt ttgaagtaat
     2581 caatttaacg gcacgaattg catcgtcgtt tgaagggatt actacgtcga tttcatctgg
     2641 atcgcagttt gtatcaacca tagctacgat tgggatattt aatttgtgtg cttcttgaac
     2701 agcaatacgt tctttacgtg ggtcaacgat gtacattaca tctgggattc ttggcatatc
     2761 agcgataccg cctaagaatt tttcaagacg ttcacgttct ttgttcaaac cagcaacttc
     2821 ttttttaggt agaacttcaa aagttccatc ttcttccatt gcattgattt gtttcaaacg
     2881 gctgatacgt ttttggatag tatcccagtt tgtcaatgtt ccgcctaacc aacgatggtt
     2941 aacgaagtat tgtcctgcac gagttgcttc ttctttgatt gcttcttgtg cttgtttttt
     3001 tgtacctacg aataatgcta cgccgccttc ttcagcaacg ctcttcatgt aatcataagc
     3061 tgcatctact aatttaactg ttttttgcaa gtcaatgatg tagattccgt ttctttctgt
     3121 gaagatatat ttcttcattt ttggattcca gcgacgagtt tggtgaccaa agtgtacgcc
     3181 ggcttctagt aattgtttca tagaaattac tgccatgttt gtttcctccg atttggtttt
     3241 atttttcctc ttcttatctt ctaccttgcc ggcaaacttt ttcaagcacc taccgacaat
     3301 ccaataagaa tgtggatttg ctgatgcata aagcaccctc agctattata cagacaaaag
     3361 atccgtatcg caagagcaaa tatacttttc tgctcaacat tcaatagttt acctgaaaga
     3421 taaaaagaat tcaagaaaaa cagtagattt ctctttgttt ctttattatc ctttttccat
     3481 aaaataattt taggtataaa agacgaatat tattgggcaa tccttctttt ttttgttatg
     3541 atacatgtga aatctttcgt aaaggagaaa gaaaatgcgc aaagctcaaa gacatttgct
     3601 gattaaacaa gtcattgaag aattcccgat ccgtacgcaa gaagaactat taaacaaact
     3661 tgggcattat ggcgttaccg ccacgcaggc aacgatttct cgagatatcc gtgatctaaa
     3721 aatcgtgaag gcacctgatg aaaatggcgt ttcccgcttc gtattgtttc gcgaaaaagg
     3781 aactcctgag actaggactg aggaagagga tcggctggtt caaatgattg aagacattgt
     3841 attgaaagtc gaacgagtcc actttttgac gatcgtcaat accttgccag acaatgctca
     3901 tttatttgca tctgttttag atgagatcaa acctccctct attgtcagta caattgctgg
     3961 attcgatacg atcatggtca tctcggaaaa tgaggaggac gcaaaacgag tagaagaatt
     4021 tcttcaccat ccaactgaag tatcactttt ttaatcagag cacgtattcc taatatggaa
     4081 tgcgtgtttt tttattttca atattttcct tattgaataa acctttacac tctttacaaa
     4141 aatacatcat tttttattca aatttttcaa caccttgatt gaatcacaat aatcatcatt
     4201 tatattggat gttaacaaga gcagcttctt gctctttgtg tatttcaaaa aagaaatgaa
     4261 aggaaatcat atgtataaat tattaacttc tggaccattg acgacttctg aaacagtgaa
     4321 aaatgctatg ctgatcgatc attgtacttg ggatcaagaa tacaaagaaa ttacacaatg
     4381 gataagaaaa aaattattgg atcttgctca agtatcggaa ggaatataca caacggtctt
     4441 aatgcaaggt agcagctcct tcggggtaga atcggtatta agttctgtga tcaggccaga
     4501 agatactgta ctgatttgtt caaacggcgc atatagacaa cgaatgatca acatgtgcga
     4561 atgtctgaaa ctgaactata ccgtttatga ggtatcggaa catcaaatcc tccaagctca
     4621 tgtgattaca cagctgattg aagagaatcc gtctatctcc gcactagcaa tggtccatag
     4681 cgagactact tccggtattt tgaataattt ggaagagatt gctgctgtca cacaagaaag
     4741 agatcttttg tttatagtgg acgcgatgtc aagctttggt gggataccga tttgtgtagc
     4801 cgaactaggg attgattttt tgatttccag ctcaaacaaa tgtattcaag gtgttccagg
     4861 cttttctttt gtacttgcta ataaagcgga actggaaaaa cgaaaaaatg ttagccgaag
     4921 tttgtcactt gatctatatg accagtaccg cgtgatggaa aacgagaatg gcaaatggcg
     4981 tttcacttcc cctacccata cggttttggc ttttcaacaa gcgctgaagg aactagaggc
     5041 agaaggagga atcgaaactc gatattcacg ttatctcgcc aataatcatg tgctacgaca
     5101 aaaaatgaca gagatggggt tccagccttt cattcaagaa tatcaggggc cattcatcac
     5161 ctcttttctt taccctaagg actggcgatt tgattttaat catttttatc agtatttaaa
     5221 gcaaaatgga tttgtgatct atcccgggaa aatcagcgat catgaatgtt ttcgtatcgg
     5281 aaatattggc gagatctatc cggaagatat tttggaactg acagcaatta tcaaagacta
     5341 taaggagaac gttaatgatt aaaactgtaa tttttgattg ggcaggaaca actgtggact
     5401 ttggctgtat ggctcctgtc cacgctttta gaaatgcttt tctagaaaaa ggaatccaac
     5461 tgactgacaa agaaatccgc taaccgatgg gaaaattaaa atgggatcat atccaacagc
     5521 ttctttccct cccttctgtc aaaaaacaat ggatagctat ttatggacaa ctacctcagg
     5581 aaaaagaggt ggaggaattg tatcaacaat ttgaacatta tctgtttaaa gatttggtca
     5641 agcattctac cttgaaaccc gacacattgg aaacgatcga acggttgaga aacgctggga
     5701 tcaatattgg ttccacgaat ggatttaatg ctcctatgat gacaatcgta gcagaaaccg
     5761 caaaaaaaga aaggtattca ccagacttca tggcaacttt tgaagacgtc gaagggtatg
     5821 gtcgaccgtt tccttatatg atccataaaa acatgcagta cttcaaaaac aagtcggttg
     5881 atgaagtaat caaagtcgga gatacggtct cagatatcca ggaagggaaa aatgccggag
     5941 tgttgacagt aggtgtaatt gaaggtagtt cgctaatggg gatttcttat gatgagtacc
     6001 aaaaattaga gatggggaaa aagatcgttt aaaacagtct gttgctctta gattccaaca
     6061 agccggcgct gatatttgtg taaacaattt aaaagagtta acagaataca ttttgtacgc
     6121 tgacatgaat ccagaatgac ttttatacaa aataagaggt tgtgaaaaag ctgtcctgta
     6181 tcaagtaata aaaacagcca agcaaaaata gctcctcata tttttcgttt ggttaggctt
     6241 attaccgcag atgcaagctt ttgaacaccg tttattcgaa aaaaaaaagg gagctgtgac
     6301 acgacttttg tcacagtccc cttatttgca aacaaacagt gtttaagaga caacctctcc
     6361 actaaacggt gttcattcag ctgactctcg gtatttgctc aaaaaacgat aaaatttgaa
     6421 aagctatttt ctcttttgtt tctctaatac tcggatcaga acgctgattt cacattctct
     6481 ttttcttaca tcttatctgg tgcatgaagt cctagcaaac gaaggtcttc tttcaataat
     6541 acagtcactg cataaactag agctaagcgt gcttcttttt gttcatcatc agctaaaatc
     6601 ttcgtatgag catagtattt gttgaatgct tgtgctaatt tgattgcatg tttcgcaatc
     6661 actgacggtt cgtatttttc cccagcagac aagaccgttt cagggtattt ttgaactaat
     6721 ttaaccactt cccagctggt atcgtcattc aatgcatagt ctgctgtttc tgaagggaca
     6781 aatcctgctt tttccaacag gctgactgca cgagcatgtg tatattgcac ataaggtcca
     6841 gtttctcctt caaatcgaac aacttcttcc aggttaaagt caaatgtatt cagtcgatcg
     6901 tttttcaaat cgtggaaaat gactgcccca accccaactt gtttagctac agcatctttg
     6961 ttttccaaat cagggttttt ctcgctgatt tgttctttag cagattggat tgcttcattt
     7021 aatacttctt ctaataagac gatctttcct ttacgagttg ataatttttt accaccttgc
     7081 gtgatcaaac caaatggaat atggtgcatg tcgtcagacc agtcaaagcc catttccttc
     7141 aagacagctt tcaactgttt aaaatgatag ctttgttcat tccctactac atatagagat
     7201 tgtttgaagt cgtaagtacg tttacggtac aatgcagcag ctaagtcacg tgtaatgtat
     7261 agtgtcgcac cgtctgactt cttaatcaac gctggattca ggtcataagc agataggtca
     7321 acgatctctg cacctttatc ctcgttcagc aaatgttttt cttctaaaag tttgacgatt
     7381 tcatccatct tgtcattgta gaaagcttca ccgttcaacg aatcgaaacg tacttccagc
     7441 agatcataga ttttattgaa ttctttcatc gattcatcac ggaaccattg ccataattga
     7501 atagcctctt tatcgccttc ttccagacgt ttgaaccaag cacgagcttc ttcatttaat
     7561 tctggttctg tttcagctac ttcatggaat tggacgtata aacgaagcaa ttcattgatt
     7621 ggttctgctt taacagcttc ttctgtaccc cattttttgt aagcgacgat cagttttcca
     7681 aactgtgttc cccagtcacc taaatggttg atgcggattg gctgataacc gattttttcc
     7741 ataatgaaac cgatcgaatt accgataact gtcgaacgca aatgtcccat tgagattggt
     7801 ttggcaatat taggagaaga catgtcgatt ggtactgttc cttgattccc gatgttgcta
     7861 tccccataat gttctttttc tttcactact gtttgcaaaa cttttttgct gataagttct
     7921 ttattcatga aaaagttcaa gtaaggtccg acaacttcga ttttttcaaa gttggcagaa
     7981 tcgatttttt ctgctaaatc tgcagcgatt tgctgtggcg cttttcggta aacttttgct
     8041 aatgaaaagg ctggaaatgc aacatctccg tgttcagctg attttggatt ttctagtaat
     8101 tgctcgactt gttccagtgt taaatcatct ttgacagcgt catagacagc ttttgcgaca
     8161 agatctttat tattcatctt tattcctcct aaagtgttcc cttgattgtt aaacaaaaaa
     8221 aatctctagc gacggcatac ttagtatgcc atcactagag acgagatttc ccgcggtacc
     8281 actccaattg tcctaaaaaa ggaccagctc catctgatat cggtagacga ccgtctgttt
     8341 aaaacagaat tctccaagtg cgcttcgttg tatcttcttc attcggcttc caccacttcc
     8401 gaattcgcta gccaagaatg atacaagtac tctcttgttc aacaaatctt agtcttatta
     8461 aactttcttg aattatatca gaaaaaaaaa cgaaaggcta gtcgtttcat aaaaaaacaa
     8521 tccagatggc ctaaaggaga agaaatacca cctggatagc tataaatcat ttcgtaaata
     8581 cgaaagactt aacaaattaa tcagctacga taatcgttcc ttcttcagaa gctaaaagat
     8641 tctcgatatt ttctaaagaa gtgatgattg ccttagcgtt tggttttgct tcaacaaatg
     8701 caatagctgc ttctactttc ggaagcatgc ttcctggagc gaattgcttt tcatcaatgt
     8761 attgtttcat ttctgaaaca gtaacagttt ctaatttctt ttgatctggt ttttggtaat
     8821 tgacatacac attgtctact cctgtcaata cgatcagcaa atccgcatcg atgatttcgg
     8881 ctaatttttc tgaagcaaaa tctttatcga ttacggcttc tcgtccttct aatccagtag
     8941 ctgtttctac aacaggaatc ccaccgccac caacagagac tgtgataact ccttgatcga
     9001 ccagcgtttc gatgacacgt gcttctttaa tcgagatggg tttaggggaa gcgactactt
     9061 ttctccatcc acgtccagca tcttctttga atgtcacagt ggagtcagca ttcatttgtt
     9121 ctttggcttc ttcttccgtg tagaatggac cgactggttt acttggattt ttgaatgaag
     9181 gatcattttc atccacaata acttgagtga ctaaagaaac cacatcttta tcgatccctt
     9241 tttccttcag tacttcgccc atggcgtttt gtaaccagta accgatagat ccttctgtca
     9301 ttgcaacaca tgtatctaaa ggcattgccg gtgttttctc agaatcagca gcttgctgct
     9361 gaatcaatag gttaccgact tgcggaccat ttccgtggga gatgatcaat tcatctcctt
     9421 gttcgataaa tttcactaaa tactttgctg tttccattaa cgcttcttgt tgggcttttg
     9481 cacttgcatc cgtagacaag atggcattgc cccctaaagc gacaactact tttcgtttgg
     9541 ccatttcatt cgtcctttct tcagttctac cgaattttct agataacaaa acgagccagc
     9601 gttttgtgat tttccctcaa tgctgactcg ttttttcgtg agatgaatgt ggttatgctt
     9661 aaacgcgagg gataaacaag ttacctaatg ttgctgccat gatcgctttg attgagtgca
     9721 tacgattttc tgcttggtca aattgacgag catatttgct gcggaagact tcatctgtta
     9781 cttccatttc agtgatgcca aagcgttctt tcatttgttc accgtaaaca gtgtttgtat
     9841 catggaaagc tggcaagcag tgcaagaaga tcaaacgatc tgtgttgtgt gttttttcta
     9901 ccatttccat attgatttgg taaggtttca acaatttgat acgttcttcg aatttatctt
     9961 cttcacccat tgatacccat acatcagaat aaaggacgtc tgctccgtct acacctttat
    10021 caacatcgtc ggtaatcatc aattgtgcac cggatttttc agcaaagcct tctgccattt
    10081 tgacgatttc ttcttcaggt tgtaattctt ttggtgcaac gatacgcata ttcgctccta
    10141 aaattgcacc tgtgactaat aaagagttag ccatattgtt tcgaccatct ccgcagtaag
    10201 caacagtgat accttctact gttccaaagt tttcttggat agttaaaaag tcagcgatca
    10261 tttgtgttgg atgccattca tcagtcaagc cattccaaac tggaacacca gagaattctg
    10321 ctagttcctc taccattttt tgactgaatc cacggaattc gattccgtca aacatacgtc
    10381 ctagtacttt agctgtatct tctgtggatt cttttttacc taattggata tcatttgcac
    10441 ctagatattc aggatgtgca cctagatcga tcgctgcagt agtaaatgca gaacgagtac
    10501 gtgtagatgt tttttcaaat aaaagcgcaa tattttttcc ttctagatag tgatgtggga
    10561 taccacgttt tttcaagtct ttcaagtgtt ctgaaaaatc gatcaaatat tgtaattctt
    10621 cttttgtaaa gtctttttct gctaataagc ttcttccttg gaatactgat tctttcatat
    10681 taaacattct cctttagatt gtttttattt aagattaaag aggaaatccc gacggcagct
    10741 gacagtaaga ctgccgtcag gaaacaaatt acttcaagtc ttcacggaca agtggttggc
    10801 tcatgcagcg tggaccacca cgacctcgtg acaattcact tgaattgatt tctaacactt
    10861 tgatgccata gctacgaagc aattcgttcg atacataatt tcggttataa gtgactacaa
    10921 cacctggagc gattgccaat gtgtttgatc catcattcca ttgttctcga ggtgcaacga
    10981 tctcatctcc attaccagtt gggatcagta caagatcatc taatccaaga gcagctttca
    11041 tcgtttcgtg taagttatct gaatgagtaa tcttgatatc atcaccatct ggttcgattg
    11101 taaagacatc catcttaccg tctttacttt gaattgctgg atggatagtg aatttatcgt
    11161 gatctaccat tgtaaatacg gtatccaaat gcatcattgc acggttgttc ggaattttga
    11221 ttgccaacac tttttcaaat cctgaatttt ttgcgaatag gtggcgtgct aatttttcta
    11281 aagctttcgc attagttcgt tgagaaatcc caacagctac tactttatcg cttaagatca
    11341 attcgtctcc gccttcgata tgatctggat tttcacgatc caaccatact tcgattcctt
    11401 tatttgcaaa tcttggatga tgtttcaaaa tatattctgt aaacatcgat tcacgacgac
    11461 gtgcttcaaa agtcatctta ttgactgtca tcccatttcc cattgatgcg gaagggtcgc
    11521 gtgtaaagta caagtttggc attgggtcca tgtaaaatgg atagtcatcg tctgctgaca
    11581 gatcatatag actgctagaa cgtacttcga tatcttttgt acgaacccca gccatgattt
    11641 tatctaccat ttcttgcgtt tccattgata gaaggaactc atgaagaccc tctcttacag
    11701 cattcgatgc aatatgagat tcatccaaca ttttattcaa gaattgttct ttgacattgc
    11761 ctgcgtcaat cgcttctgcc gctaattttt ccaagtaaag agtctcgacg ccttcatttt
    11821 gcaatgtctt cgcaaagttg tcatgttctt cttgagcaat cggaagatat ggaatatcat
    11881 cgaacaacag acgatccata atatctggtg tcaaattttc cacttcttgt ccaggccgtt
    11941 tcagtaaaac tgtctttaat ttccctattt cagagaaaac gtgaataggt ttatccatgt
    12001 tgtgttgcct ccttcttttt gattacatgt ataggatatc ctccttttgt aatcactttc
    12061 ataattttgt ctcattcaaa atgagacatt cctcacatta atattcgata attaaataat
    12121 taaacgtttt tctattttta agcgtaattt attcattttt tattctgtat acactttcaa
    12181 aaaaatattt attcattgaa aaaatttttt tgaataaatt aaaaaaataa attatattat
    12241 cgttgttagc gtttactata tgtattattg ttgtttttta tacacaaatc attcgcttca
    12301 aaacaaatta ttcaatacca ttgtatattt tttacataat aacaaattat atttgtaaag
    12361 tattaaaact tgtttctaat gttggtatgt taaaacttta caaattcttt aaaaaaagtg
    12421 acaataaata tagtgaacaa taaggagagg actttttaat gcgtgttaat aaaatcgatt
    12481 ttcacttttc aaaactcaga tatcaacctg attttgaaca tttctcggat gaagagttcc
    12541 aacagatcaa ggaacatact gttcttcgtt cttataaaaa aggacagatc cttttcgacg
    12601 atggtgatcc cagacaacgg ttgtatatct tgaccaaagg actcgttcgt ttagaacgtt
    12661 atgatgaaag tgcaacttat tactactatg actatgtgaa tacaaataac ctttttccta
    12721 tgtcaggaat gtttggagaa gagacctaca cttatacagc tcaagcgatg actgatattg
    12781 aaacattcta ccttcctgtt tcctactatg aaaaattagc acgaaaaaat cccgaacagt
    12841 tgatctatat gatacaaaaa atttctaaag tagttgaaat acatgaattg cgtatccaaa
    12901 tcggattgac ctctagcgcc tttgaccggg taaaacaaaa tttattcatt ttgaaagaag
    12961 aattgggcgt accaacaaaa gatggtcata tcaccattcc ttatccgatc accttaaaag
    13021 aattagcagt gaatagcggc acgacacgtg aaactgctgg acaagtaatc aaacaactac
    13081 gtgattccgg gctgttagat tatgacaaaa agcgttttac tttctgtaag acagctacta
    13141 ctccagctat gagagaataa cgcgaacaaa aataagcagt gaccctgata aatatcaggg
    13201 tcactgctta ttttcctccc taaaacttct gaaagatccg gcagttttag atcactggac
    13261 aagactcaaa gattttctat gtgtgtttca gttatgtaat attcactgtt tgcaaaaaat
    13321 actgttagat taactagatg aagcgtcttg tcctcatccg atctagatta ttcgatattc
    13381 ctcgacaata aacgattact cagtgagggc aatcagagga acggataatg ataaataagc
    13441 tgtaaaaaat agcaaaataa caataatgat taaaagtatg taaaaaatag ggctttgaca
    13501 aaaacgtgtc acagccctat ttcgattaaa cggtgtgtac ctgtcaactc ttcggtcaca
    13561 agtcataatg ttcataaaca tgaggagctg ttttttgaaa ttgttccttg tgaatcagag
    13621 ttaaacgaca ggcttacgaa ctcttgatta aacggcgttc aaaagcttgc atacgcggta
    13681 ataagaacag ccaggtcaaa aacatgagaa gccgtttttc ctgggctgtt cttattactt
    13741 gatgcagggc agctttttca caacctcttt attcagataa aaccaagctt ggatcagcat
    13801 tcaactgata gctagcaaaa tttctttttt gcatttccac atgtgctgct gctccaatca
    13861 ttgcagcatt atctccacaa agtcgaagag ggggaatcac tagttctacc tcagggagtt
    13921 tagctgccaa agcatcctgc aatccttcac gcaacccttg attggccgct acacctccag
    13981 ctataatcag ttgcttgact ggataatttt gacaagctcg aagtgtttta gtaatcaata
    14041 catcgatcac acttgcttga aagctagctg ctaaatcatt tttgtctaga tcttctccac
    14101 gctgttgtgc attatgcacc aaattgataa atgcactttt taatccgcta aaactgaaat
    14161 cataattatc ttcatggatc atcgctcgcg gaaaatggta attatctttt ccctgatgag
    14221 ctagctgatc gatttctttt ccgcttgggt aagaaagacc taatactctt ccaactttgt
    14281 cataagcttc tcctgctgcg tcatctcttg tctccccaat gatttcatat gatccatctt
    14341 cttgcatata gactaattct gtatgtcctc cgctaacaag aagtgccatc aatggaaact
    14401 ggaatggttt aaccagacgg gctgcataga tatgccctgc catatggttt acaggaataa
    14461 gcggcaattg gtgtgcccaa gcaaaagcct tagctgcaga aataccaatc agcaacgagc
    14521 cgacaagtcc tggtccataa gtgacagcga ctgccgataa atcttctgcc gacacaccag
    14581 cttctaccag tgcatcttcc aagcataagg tgatttgttc tacgtgatgg cggctagcta
    14641 cttcaggtac tacgccacca aaacgtttat gactgtttat ttgagaagca acgatgttag
    14701 ataagatctc tgttccattt ctaacgaccg ctacactcgt ttcatcacaa cttgattcaa
    14761 tcgccagaat caattcttca ttcatttcat cgtctccgtt tttaactttc tgctcataat
    14821 gatcgcatct tccgtcggat tgcgataata tgatttccgt ttacctaata tacgaaactt
    14881 ttctgattca taaagttttc ttgctgcttc attagataga cgtacttcta aaaaaacatg
    14941 cagcgaatct tttatttgtt ccgtaatcag taattgtaac aaatgccgtg catgcccttt
    15001 tccttgttct gaaactgcaa cagcaatatt tgtgatctcg acttcatcta ttactttcga
    15061 gtatccaata aagccacaga tctggttatc ttcagctaaa agcagataat cagagtgagg
    15121 ctgttggatg tctgccaaaa actgcatttt cgtccaaggt gaaccatgtg gataagcatt
    15181 ttcgctaatc atccatacgc attctgccaa gtacgcttca tcaaaatctt tttttctgca
    15241 aatcaactaa tctcactcat tttctaaaag ttttatcata tccaacgcat cttcttttgt
    15301 ttcagtgtaa tatctttttt tgatcgttgt tgcttgaaac cccaatttcc gataaagtct
    15361 ttgtgcatct tgattactca tacgcacttc taatgacatc gtctcacagc gattcattat
    15421 agcaaagttc tcgatttcgt caataagcag cgaaccgatt cgtttacgct gatatgccgg
    15481 tcgaacggca atattcgtga tatggcaatc taaaccgaac gctcttgaac cgataaaacc
    15541 aatcattctt ccattatcaa agatacctag atatagatga ggaagcggtg acttcaattc
    15601 tgatataaag gcactttttg tccatggcaa ttcgccatta tagacttctc gttcgacatc
    15661 cagcagctct ttgatatctt ctgtagtcaa ttctcttagt acgtaacgac gatcgatttg
    15721 ttcgactgtt ttttctgtat aaatcatttt atcttgaaaa aagcttctgg catacgctct
    15781 aaattttttc aacataactt tcgtctccag gtgtgtgcgt ctccaaccat ttttcttctg
    15841 cttctactcg ttttaaatag cgaggaagaa aagcttgttt ctctgcaact ggttcaacta
    15901 aagcacctaa ttgagccaca gttacaccac ttggaatatc ccatgctgga actgtattaa
    15961 tcatcgcact aggcaatatt tcctttattt cagagaagaa tttgtgacaa tcactcccga
    16021 cgaaataaat agcttcattc agcttttgta gttgtgtgaa caaatcagaa gcagaaatat
    16081 gtacatcttc aagtacagtt tctaatctat tttctttcca gcggtatgcc ccagcgtata
    16141 cattttttct tcgagcatca aacatgggca caataatatt atccacaccg atgcaattag
    16201 ccgcgatggt tttcagacta gatactccta ctagctcttt atctaatgta taagcaatcg
    16261 tttttgctgt cgttacacct atacgaagcc ctgtataaga accgggacca tcagaaaccg
    16321 cgattcggtc aatgtctttt ggacttattt gaagatctgc aaacaattgg tcgattgcag
    16381 gcatcagtgt tacactgtgg ttgcgtttga tatttgtttg tatttgtcca agaatttgtt
    16441 cgtcttctac cacaccgatc gccaaagttt ggtttgcagt atctattcct aatgtaatca
    16501 tatatttgat cctttctgct atgacattct cgccttccat tgtagcatac ttttttattc
    16561 tgaggatgaa aataccaaag gcaaaactag tacaataata catgattatc tgctggcggg
    16621 caaattttgc cccttcctga aacacaaaaa agctgcggta tcactccatt ttcccacagc
    16681 ttttccatct tttatttcgt tgattctcga ataatcaact ctgtttccac aataatcttt
    16741 cttgaaaccg gtgctttgga attacttaat tgaagaatcg tctccactgc tagctctccc
    16801 atccattcgg tataaacttt tacagtagaa agcgagggcg ttacatattt cgctacactg
    16861 acatcattga agcccatcac agaaatatct tctggtacca ctaaaccttt ttcttgaatc
    16921 gctttcagtg cgccaatcgc taatgcatca ttagctgcaa aaagcgcatc aggaacatgc
    16981 ggattcgttt ttaaatattg cttcactgct tgatatcctg actcgacaga aaaatctgct
    17041 tcgataattg gaccttcgtc gtagcctttt tctgccaaaa cttgttgaaa tgccataatt
    17101 ctgggatctt ttagccgctg atggtttttc ttcgtatatt ctgttccagc aagcatagcg
    17161 atatgttgcg ctttatggga gacaaagtgt tcaatgactt tttgaacact tgacttaaag
    17221 tcgacaacta gagagtcgat tccttgagaa gtgccgtcag aatctaccaa aagcaaggca
    17281 ttttgggatc ctttcatttc taataactga gcttcgtcga attttcctag tgcgatcgtt
    17341 ccatctgccg gaagatcact aatggaatcc cacgtttctt tcaataaagt aacgtttgct
    17401 tcttctgcct ttttttcgat tcctaggcga atagataaat aataaagatc ttcaagctct
    17461 tccgtatcgt cgtaccactg gatcaggcga agcgtttgct tagtatttgc tgcattttta
    17521 cgatgtttcg tataatttaa gcgttctgct gcttcaaaaa ttttttgctt tgtggctaag
    17581 ccaacggaaa gatcaggatc atagttgaga actcttgaaa cagtagcagg agaaactcct
    17641 gccaactgcg caatgtcttt aattgttgcc atttgtctct cctccttttt tacgtttata
    17701 aaatcgcagt aaatcgttca aacgctgcct gtcctttttc atctcgcttg aatactccag
    17761 cgtcttccag tacacgtgca aaaacctgac ctacagattt ttgtacgaca tcggtgaccg
    17821 tatctttcgt caaatcagga tgttcttttt ttaattgttc tgcccacgga cgatgatatt
    17881 cagccatctg gttttcttct cctaataaga aatgctctac ttctactagt tctggtttca
    17941 aacgaggtgg taaaacagca agccccatta cttcgatcaa cccaatgttc tcctttttga
    18001 tatgttggac atctttatgt ggatgaaaaa tcccatcagg atgttcttct gaaacattgt
    18061 tgtctcgaag gacaaggtcc aactcaaagt aattgtccct tcttcgtgca attggcgtaa
    18121 tcgtatggtg tggtgtacca tctgctgaaa aagctctgat agatactgtt tcatccgaat
    18181 atgctttcca tttttccaat actgagttag ctgcttcaat aagcaagttt ttctctgttg
    18241 attgcaaacg gatcacagac atcggccatt tcacgactcc tgcgatgact tgcggataat
    18301 cttctagttt gataagtttt tctatcggtg cttttgccat aggaaattca tgacgtcctg
    18361 cctgataatg atcatgagaa agaatcgatc ctccaacaat tggtaagtca gcattcgaac
    18421 caacaaagta atgaggcaag acttcagtaa tccgaagcag tctagcaaat gtttcctttg
    18481 tgattttcat cgggcggtgt tgttctgata aaatgatcga atgttcattg taataagcat
    18541 aaggggaata ttggaatccc cagctttcac cgtctagatt cattcgaata atccggtgat
    18601 tggtgcgggc tggatagttc aagcgacctc tatatccttc gttttccatg caaagcatgc
    18661 aggtaggata gtctactttt accgcctcgc gttctgctgc gatttgtttt ggatcttttt
    18721 ctggcttaga taaattgatt gtgatttcca gttcaccata ctccgactct gccggaaatt
    18781 tgatgttttt tgcgatggct cttgttttga tgtagtcatt tttcttactt aaattaaaga
    18841 aatactcagt tgcttcctct gggcttttcg aatagtgctg tgcaaagaat gcattgacga
    18901 ctgaaggtgg cggtgtgaga aaatccatta attgcgcttc aaaaatctct tgttctgctg
    18961 gcaattctga aagaacacca ttttctcttg ccttagcgac aagctgatcc aataagtcta
    19021 cagattcttc cttaactggt cttacttcaa tgctttctag agcatcttct cctaccatcc
    19081 ctaaaagacg attctgtaaa tataagcggt ccatttccat ccatccgcca gcttcgatcg
    19141 caagtgtggc aaaatcacaa atcgtttgac tgattgacat atctcattcc cctattcttc
    19201 ataaccattt ggatggctga catgccaatc ccatgctgtt ttgataatcg ctttgatatc
    19261 tgtgtattca ggtttccagc ccagaatctc tctcgctttt tcacttgaag cgactaatcg
    19321 gctaggatct ccagctcttc ttggtgctat ttctgctgga atttcttttc ctgtcacttc
    19381 tctagctgct tctagcattt ccttgactga gtatcctttg ctgctgccta aattgaagaa
    19441 gttgctttca tttccttctt tcaagtattc caaagctaaa atatgtgcag caatcaaatc
    19501 ttctacttga acataatctc tgatacatgt tccatctggt gtatcataat cgtctccata
    19561 aacagccaag gcttttcttt gaccaagagc tacttgtaaa atgattggga caagatgcgt
    19621 ttctggtgta tgatcttctc cgatagatgc atctgctttt gctccggcta cattgaagta
    19681 gcgcaaagcg acatagcgca tgccatatgc ttggtcacac cacttcatca ttttttccat
    19741 catcaattta ctttcaccat acggattttt aggattagct ggtgtatctt ctgtgattgg
    19801 agactctttc ggctctccat aagttgctgc agtagaagag aatacgattt tattcacgtt
    19861 gaactcgtgc atgacttcaa gtaagatttg cataccgtat acgttgttgt tgaaatacat
    19921 caatggtttt tcgacagatt ctcctactaa agagcttgca gcaaaatgga ttactccttc
    19981 aatcggttcc ttttcaaata cggaacgtag aaattcttta tcccggatgt ctccttcata
    20041 aaaatgagca tctggatgta ctgcttgttt gtgacctgtg agcaaattat ctaccacagc
    20101 tacttgatac cccttttgaa ctagctggtc tacagcgtgc gaaccgatat aaccggctcc
    20161 gcctagtact aaaattgtca taaaaaacac tcctttgatt agtaaaattg tgtttgttga
    20221 ttctatataa tttaaaaaac gaagtttact tttatggtga aaacaaacaa agtaaaattt
    20281 cgtaaattca tatggtaaat ttataataaa acatttagta aacattttca agggtttttt
    20341 gcaaaggttt acaaacaaac gtaaaactag cctttttttc tcttttgttc cataatagat
    20401 ataacaaata ataaatgagg tggattcaat gaaaaaattt gtatctggaa tattagtagg
    20461 aagtctggca acagccgctg ccgttgctgg tttggttgct tctgtgaaaa aaacagtgat
    20521 cgatccaatt gacgaaaaag aagcaatgat cgaagaaaac cgtaaaaaag caatgcgtaa
    20581 acgcgtttct cgttaataat tatttaaaaa tacgcatgaa gactttctaa aaaacagata
    20641 agtcatcatg cgtattttta tttgtcagtc aatataagtt gtgctatttt atctgcctgt
    20701 ctcagattcc atggatctgt ataaggtcta gctactgctg cagttagcca atccacacct
    20761 tcaacaggta ttccatagca ataaaagtca gactggattt cccctgaagc atcaatcacg
    20821 cgattcgtac ctcgctcaac atctatagct tctgaatgat aacttcctgt attatctgaa
    20881 aatgaaaaag ggcgaacaag tttgttttcc ttcaaatttt ttatgacagg attacttgaa
    20941 cgagaaaagc ttgtttgtgg caatcgagct tcaatcaaat agcgactgct gatttcttta
    21001 tcttgtagag aaataacata gcggttgtgc ttttgctgaa tatcaaatgg cggttcgatc
    21061 aaatgaaaaa tacccgcatc tatcagtgct gctaattctt tcgtccgaat gattggcgga
    21121 ccgatcgtta aaaagctatt tagatgagta aaccatcccc atagtatttc tttgtattcc
    21181 ttagcagaaa aaacgtgcca ttcaatagcc tgccggattg gatcacgcca gtcttttaat
    21241 gcatcaaatg ttgaagcaaa tgctcctgtg caattgcctt tttccgcttc ttttatctgc
    21301 ccttcaataa atattcggct agcttctgaa aagggctcat tctgataggc aagaggagtt
    21361 tctaaatacg accaatccca tctataaggg attagtgctg gatgctttcc gagacactcc
    21421 tctgaagaga gggagagaaa atcatgctca aaatttttct ttggaatcgg caagtgatat
    21481 tcttcgatga ttttcttgta ataaaacaac tcaacgtctt ttttcagata gtcaaaaaat
    21541 gtttcgccag tcaaaaatcc cgactgatgc cattgctcca ggttttcttt tgttagtaac
    21601 cgtggccatg ccattgctcc gccttgcttt tgatttcttc ctcgagggta ataagggagc
    21661 ccccttcttg atccactgta tacaatcggt tccttgcctg atggatgata gaccagtttt
    21721 cccttttcgt tctcgaagcg ccctcctctt gatactgtaa acaatccgac ataatcaaaa
    21781 aaacttaagc ctagacctct taaaaagaca ttttctttag gcggtatctt cgaaagatct
    21841 acatctgcag gattagaagg aagctgatac agtaaaacat ttttctttgc gtagtctacc
    21901 cacactcttt cttcttctgt ctcatcattt tcccagtgac cgcttgctaa aacaagctga
    21961 tcgatagaat agctttgctg atctgtctgt aaaagataac catcttttct tttgcttact
    22021 ttttttacta aagaataaac aaactgaata gaagctggaa attcttcttg caactttgag
    22081 aaaaaccagc gttgatagag tccgtataaa catcgagtag attgctgatc tttttccaga
    22141 cgattgattt cttctataat tagttgctta tttttggtta ccgtctgttc gatataatct
    22201 gtagcaggtc ctttactcca ttgaaacaag ttgggtccct gtgttaccaa tcctccactg
    22261 gacaatgttt catctgtaaa aagcgtcact tgttgagaaa cagaattcat taataactcc
    22321 ggtggctgat tcaaccgcca aactcgacct ccaggaccat tgggatcgaa aagaaaaagt
    22381 tcaagagaat gtctgtcctg attattatgg agaatccttt ctgctacact taatcctcta
    22441 ggtccggcac caatgatccc tattttcatt tgcatgcctc catttcgata aattttttca
    22501 ataaaacagc atggttctga tgttcatttt ttgcaccata aacaaaagta atgactggat
    22561 gttctttcat aagttgactg agtttaaaaa tagcttgctt cttttcttct tcgaaaatca
    22621 attcttgctg gtatttcttt gcaaatgaag caaatcgttc tggtacatgg tcaaaagttt
    22681 tgcgtgcttc attactaggt gcaatttctt tcaaccacag atctaactgc gctttttctt
    22741 ttgaaattcc tcgtggccag aatctatcca cgagtattct atagccatcc tctttttcag
    22801 catcaaggta aacacgtttt aatttgatca tagttgtttc cttctttcta ccttttcgct
    22861 tagcttatat atgtagataa tagcacaaaa taaaaaaaat gaacggcaca actatccatt
    22921 gcgccgttca tgtgatcttg gtcaaaatct aatgattgat tcggttttta aagctgtcat
    22981 acaatcatct gttttatact tttttacttt tgatttttcc agaccatccg tcatatccac
    23041 ccttaagtaa ataaatctct tgataacctg ctttacgtaa tttatttgct gtacggatgc
    23101 tcaaactttt cttttgatcg taaatataga caggctggtc ttttcgaata gatcctaatg
    23161 aatctttcaa aacagtgtaa gggatgtttc ttgcacctaa aatatgccca gcatcaaaca
    23221 catctttttc gcgaacatcg attacttgtg cttttctcat tccttctcga aattcttctt
    23281 ctgtcaaagt cgttgctgaa cgtttggcca ttactcgtag atagacttcc caaaggatga
    23341 ttgcaagcac aatcaatagc aaaatgatat taattaccca taaaaccatg taatgcctcc
    23401 gtttttttaa gcaaatttca aggctaatga ggcagcacca atgacaccag cttcattacc
    23461 aagctctgct aatttgattt ttgttgattc tcttacttgc gggaaagtaa attctttaaa
    23521 atatttctct acacggctac gtaaaaattc tcctgctgcc gatactcctc cacctaacac
    23581 gatacttgac ggatttaatg tattccccaa gtttccgcaa gctaaaccta agtagaagca
    23641 tacgcgatca acaaccatca atgcaaacgg atcgtcttct tgagccattt caaagatatc
    23701 tttacttgtt acttcttctc cgttgtctag cattgctttc agttttgaat cccctgcgta
    23761 ttcttctgcc aagaaacgac ctaggcgtac cacacctgta gcgctagata cagtttctaa
    23821 acatccgcgt ttaccgcaag tacattcgaa cccttcagga tccacagtga tatgtccgat
    23881 ttctcctcca gctccgctca cgccgtgaat caaatttccg ccagcaacga tacctccgcc
    23941 aacacctgtt cctagagtaa cgaatacaac gtctggatcg ttttctccag cacctttcca
    24001 tcgttcacct aaagcagcaa cattcgcgtc attatcgata gcgaatttga ttcctgttcc
    24061 tgcctcgatc agttttttca caaattgaac ttctgtccag tttaagttat acgcaccaat
    24121 aaccgttcca gcttcgctgt ccacgcttcc tggggtaccc atgccgattc cgataaagtc
    24181 ttcggctttc atattatata aattcaaacg atgattgatt gattcaatga tttcaggaac
    24241 gatatgctta ccatcatcca aaatattggt atcgatgctc catttttgct gaatctctcc
    24301 ttctggtgtt aaaattgcaa attttgctgt tgttccacct aaatcaatcc caataatctt
    24361 cttgtccatt acaaatttcc tttctttcgg ctttcttcaa ttcggtgctc tctttttaat
    24421 atgcgccacg ctgtcatgta tgtatcatga tcaatcaaac ggctatcata cagattacgc
    24481 aattcgatag tcattaattc aatgtcatag atgcgtgcac ccacatagat aaagatgcca
    24541 aattttttga acagctgctg tacatcatat aagctctcca tctttaagca cttccttcat
    24601 attatacaag taaaccatat ttttttaaac ccagtaaaat acatattaca aaaagaaata
    24661 caaaaactag tgtagaaaga atcctttggt gtatcgaata gcttgtctgt tgtttcggta
    24721 gacccaaaac attccctaac actaatccgc caattagccc accgacatgt ccccaaacat
    24781 ctacagaggt atccagaaga ccaaaaacaa atgtcaacac aataaataaa agaaaatgtc
    24841 tgactagctg ctggatcgct gggttatgtt taaaatgaaa ccctaagata aacaacgcac
    24901 cgaacaaacc gaatatcgaa gtacttgcac caccagacag aacattcgct tcgttaaaag
    24961 caaagcttgc tgtatttccc attatcccgc tgaacatata aatcaagaaa aaacgccaat
    25021 ggccatagat tgcctcgatt tgctgcccca taaaatacag tatcagtgag ttcattacga
    25081 aatgcatcag tccaaaatgg atgaagattg gtgtcactaa acgccaccat tcattgaagt
    25141 gaacaagata aggaccatac attccggcat aataagggat ctcaagtcgc ggaaataatt
    25201 ccatcatgag gaagaccgct gtctgtatcc ctaaaaaagc ataggtccat aacggtcgtc
    25261 ttaaccatgc acgcaatttt atttgctgtt gataattcat gaaaacctcc catttcattt
    25321 tagtcaataa acaattgttg gatcttctga tcaaagctct ccggttgcca ttgttcattc
    25381 aattgttcac gaaaaacaag gctacatgtt tttttatgaa aattatttaa ataccggtcg
    25441 taataaccac cgccaaaacc gattcgataa ccggctctat tgtagataat acctggtaca
    25501 atgaggagat cgatcatctc cggcaaatag agcttctctg attgtggctc aagaacacca
    25561 aaactcgaac gtacaagaac ggactgttca tccatttcat aaaacgccat ctgacgtttc
    25621 ggcaaagttt taggtacaac tattttcttt tgttcttttt ctgctcgttg gataaccggc
    25681 tgtgtatcca gttcaaattc attcgataaa gtcgtcccta tcacttttgc tgacttccag
    25741 tactcgctgg cgaatagctg tttatagatt cgctgttctt tttccttttt cttgccactt
    25801 ttggccagat ttttcagctt ttcgattcct ttccggcgta atcttacttt caattggtcc
    25861 aaaaactcac ccttccttct ctcataaaat ggtataggaa aaaaagaaaa atagcaatcg
    25921 aactttcaaa taaatgcata aatagaataa aaagaagacc tagaaatgat tggccttcct
    25981 tttttaatga atttcaactg ttcagcgcgt gtttttgtct gataaaaagt gcatacagaa
    26041 aatatggcgc accaaaaagg gcaatcaaaa ttcctgtagg tacttcccca cttggtagaa
    26101 tcactctagc aaccatatct gcactaagca gaaaaatgga accgaacaaa ccgctcagaa
    26161 caaaggtcca gttattttct ttacgtacga ctagcttcgc agcatgagga gctagtagtc
    26221 ctacaaaaga taaactacct gtcaccgcta cactaccgct tgccaaagca acagctaaca
    26281 acaaaaggat tttttgactt ttagccacgt taaggcctaa tccttgcgcg cgttcttgac
    26341 caaatgatag caatacaatc ctctgtgcat aaagtcctcc tagcggaatt aagataaccg
    26401 cccatggaag caatgcccaa acataaggcc agctcgcacc ccagattgat cccgctaacc
    26461 atgcattcac aaatccataa ttttccttag ataattggat cgtgcatagc aatgttaatg
    26521 cagaaaggcc ggcattaacg gcaataccgg acaataagat tcgattcata cccaaaaagc
    26581 catttcgatc ataggccgca agatagacac agcaagcagc taaaacacca cctagaaagg
    26641 ctacaactag caatagaaac ggcagcgaat agtgcgaaaa gaaacctaaa taaagcatca
    26701 ctaaaaatcc tgctccggca ttaatgccca atatactaga atctgccaat tcatttcttg
    26761 ttactccttg caagatataa ccagaaacgc caagacaagc tcctgctaat aaactgatca
    26821 gtaatcgagg aactcgaaat tctctaacaa tcagcgccaa agaagatgat tctttcccta
    26881 tgaacgtggc aaaaagctga tccaggtaaa taaaaggcgt accaatcatt aaactaccta
    26941 tagacaggat gacaagtaca aaaagcaaga aatagaacgt ccaatatatt tttttcaccg
    27001 ttgttccctc cttacttgta tcagtaaaaa cggaacgcca atcaatgcaa tgactaatcc
    27061 aaaaggtgtt tcaaaagggg gattgatcat cctcgctgta aaatccgcca acataaccaa
    27121 tccaccgcca actaaaaaag agacaggtag aacataacga tagtccgttc caaccattcc
    27181 gcgaacaact ggcggaacca acagcccaat aaatgaaaca ggtccgacta acgaaacggc
    27241 aatggctgct aacactgcaa ctagacagaa aacaatcaac cgcgttcgtt taggatgact
    27301 tccaagagct aatgcatgtg tttcactcaa atgaatcaaa gatattgctt ttcctaatga
    27361 aaaagaaacc aaaacagcaa gtatatataa aggaaacaat actgctaatt gtttccatgt
    27421 gatattggca gctccgccta caaaccaaaa agcaagatcc tgctgcagat taaagaattg
    27481 ggtaagtgct tggctgatag cagtaaaaaa agaactaata gctacgccag ctaaaatcag
    27541 ctgtaaagga ttcatgccca ttttcgaaaa ctgcaaaaaa ccaaatacga gcaaagttac
    27601 agcaaaagaa cctgccaatg acattagaaa cacagaaaaa tcagaagctt taggccaaaa
    27661 agcaaaacta agggccattg ccaacgaagc acccgcgttg attcctagta agcctgaatc
    27721 tgctaaagga tttcttgtca ctccttgcat caatgcaccg ctcaatgcaa aacaactccc
    27781 tacaagaaat gctcccgcca cacgaggcaa acgaatattt cgtatgattt ggtgactttg
    27841 ttttgatcta tcaaaatcaa acaacgcctg ccaaaaatct gctttttcca cagtcgctgc
    27901 gccatttgaa agagcaacaa aaaaaataat caaaagaaca aaacagacca aaagcaggag
    27961 tctatttttc ttcatagtcc tcataattga tcctcctgct cttttggcaa caaatcatag
    28021 gttagaaaaa ctggtttatt tgttcttgga agcgtgacaa tcgttgcatc aatctcaaat
    28081 atttttttca tacactcttt tgtgatcact tcttcaggtg taccttctgt gatcaactta
    28141 ccgtttttca ttgctaataa ataatctgaa aaacgtgaag catgattaat gtcatgaatc
    28201 gacatcaaga tcgttgtttg tttcatttga ttgatttcag tcaataactg taggatctct
    28261 aattggtgtg ccggatctaa aaatgttgtc ggttcatcca agatcaagat atctgtttcc
    28321 tgagcaagcg ccatagcgat ccagacacgc tgggtttgtc caccagacag cgttgcgata
    28381 tcccgcatac gaaatccagc tagacctgta gcatccaacg cccactcaat tgcttcatga
    28441 tcttgcgtgt ccatgccact gaacagtttt tgataagggt atcgtccgta agatactact
    28501 tcttctactg tcatacctgt agggtgttca ctagtttgtg ctaataatgc aatttttttt
    28561 gcaagttctt ttgaactgta tgtagagata tcagagttat tgacaatgat ctttcctgat
    28621 ttcacaggta gtatacgggt aaaacttttc aataaagtag attttccact tccatttggc
    28681 ccaatcaaac tagtgatttt cccttcagga atcgtaacag acatgttttc aatgattttt
    28741 ttgttttcgt agccggctgc aatgtcagct gctcttaatc tcgtcatttc acccatcctt
    28801 tcgctgaaaa tcattctcaa ttatgacgct gtttcaacat ttcgtcaagc gctactttca
    28861 tatctatagc caaatgaagc ggttgacagc gttcgaaata tcaggaataa taaccaatga
    28921 gaaagattct caattatgtt aggaggaaag aaatgaaatt aaaaacaaaa gtattcacat
    28981 tatctagcat attgctgctg gctggagtac tgagcgcttg ctccccctct tcagataaag
    29041 aaacagctac aactgccaat tcgacgactt catccaatag tactcataca gtcacagata
    29101 cacttggaca taaagtagag attccaaacg cgcccaaacg gatcatcggc agttacttag
    29161 aagactatct gattgcacta ggggaaaaac ctatcgccca gtggactgtt ggcagtggtt
    29221 ccattcaaga ttatctgcaa gatgatttaa aggatgtccc aacgatttct tatgaccttc
    29281 cttatgagaa agtgttaagc tttgagcctg atttgctgtt gatttcttct tccgctactg
    29341 tcgaaggcgg gaaatacgaa caatatagca aaatcgcgcc aacttatgtt gtaaaaaacg
    29401 gaacagatgt cacatgggaa gaacaactaa aagatgtcgg caaagctttg gcaaaagaaa
    29461 aagaggcaga aaaaatcatt tccgattatc aaaaatccat caagaaaact cgagaagaac
    29521 tagcagataa aatcgagaac aagacagctg cagtgttgtg ggtgaccaac aactcagcct
    29581 ttatggtcag caaaaatcgg tcaagtggaa gaatcgtata cgacgatctg gaatttggtg
    29641 ttcctgatct agtggaagag gtctccaaaa aagccacttc tgactggtct gctgtttcct
    29701 ctgaaaagct agctgaatta gatgctgact acatcatcct tgtgaacagt gacaaagatg
    29761 ctgccatgtt caatgaacca agctggaaga atctaaaagc agtgacagac aatcatgtac
    29821 tgcaattcgg acctgaatct agttggctat ataacggacc tattgccagt caggaaatgg
    29881 tcaatgatat caaagaaaaa ctaaattgat tttaactaaa aaaagcatct tcacgattag
    29941 tcgtgagatg ctttttttct tattaacaaa ctagacgcat agattttatt cttcttttga
    30001 agcaacccta ttttttactc tttcccattt ttgaaaacga tgggcatata gattttcttg
    30061 atccgttatc ccctcatact cctctataag ggcgaagtct gaaaaatcaa tattcccaat
    30121 atacgtatcg ccttcaaacg tgctatcgat caatgttcgc cagatccgac cagtgtaagg
    30181 aagaagttct tgaaaaatcc gactaccacc cgaaacatag atatcttctg agatcgtttg
    30241 actatacgac aaaagttcat cgatcgaatg cattacttcc gcattttctt tcgtgcgaaa
    30301 atttggttgc gttgtcaaca cgatgatatg gcgataagga agtgaaagat cccccattcc
    30361 ttcataggtc tttcttccca tcactaaaat tcgatccatt gtatgttcgc gaaagaaacg
    30421 catatcattt ggcaatcgcc atggtaacaa accatttttg ccgatcagac catttttatc
    30481 ttgtgcccac atggaaataa acatattatc cgctccttat gattttagat gttttgagat
    30541 aaaaaaagtc tcaattcttt gaccagcaag gaattgagaa ctttaaaaac attattttgt
    30601 ttcacggtgc aaagtaactt tgcgttcgcg tgggcaatat ttttgttttt ccaaacgatc
    30661 aggattgtta cgtttgtttt tgcttgttag atagttacgt tctttacaag aagtacactc
    30721 taaagtgatg tttacgcgca tgtttttccc tcccattttt acaagaatcc tctaagatga
    30781 ctctcagact tgattatctt accatgattt tttctagatt gctagtgttt ttcacgattt
    30841 tgttaagtaa aactacttga cgataaatac aacggtttta cttctcaaac aaaatctttt
    30901 tctttttgta taaataccct tacacttgtt tatatagatt atgtttttta ataaaggggg
    30961 atactaatat gccatggaac atgaaggact ttcctgcatc aatgaaaaac ttagataaat
    31021 tgacaagaaa aaaagcaatc gacatcgcaa atgcattatt agatgaaggg taccctgata
    31081 accgtgcgat cccaattgcc attgatcaag caaaaaaatg gtatgaagat gctagtgaat
    31141 cagaaaaacg aactttcgaa aaagaaaaaa atccaagcaa gacggatgaa cacgatacga
    31201 atcctcgtgc tggaaaactg cttgattcag atgtgatcgt agaatatgag gaagaacaat
    31261 ggatcgtgaa atctaaaggg gcaaaaaagg caagcaacca ttttgataca aaaaaagaag
    31321 caatcgaaaa aggaaagcaa gtagcacaaa acaaagaatc aactttgttc atttataaaa
    31381 aagatgggac aaaagaaaaa gaaatcgatt attgaacata tgtaaagggg ttgtgacgaa
    31441 aatcgtgtca caaccccctt atgttcgaaa caatggtgtt cctctgccaa ctccgaacca
    31501 taagtcataa tatctataaa acgggaagag ctgttttttg aaattgtttc ttatcactca
    31561 gtgttaaacg gtaggagaaa acctcttttt tattgatatt tgattttcat caaacagtca
    31621 catagtcgat tgcttctgct tgcggaatcg tttcatctac aaagtagact ttataccatg
    31681 tcaagaaact gaagattgtc cagatttttc tttgctcttc tttacgtcct tcgtgatggt
    31741 catctagcaa cttcatgatt ttttcttgat caaaaaattc ttttgcaaaa tctgcttcga
    31801 ataatgcttt gacttgttcg tagccgtgtt cttctttcaa ccaagctttg attggcacag
    31861 ggaatcctaa tttcacacga ttcgaccatt cttccggaag atgtttgttc gcagcttgtc
    31921 tgaaaatatc ttttgtgttg ttttgattca ataaaaactt acttggtatt tgttgagcca
    31981 atttcatgac ttcgatatcc aataaaggta ctcggacttc caaagaactt gccatagaaa
    32041 gtttatctgc ctttaacaag atatcttttg gcatccattg atgaagatcg acatattgca
    32101 tcttattgac ttcatctttg attccttctg ttttctcgta atgaacagtc atgatttcat
    32161 ccacagatgg tgctgtttga tattttggtg ttaacacttc tgatgcttct gattcttcga
    32221 acactcgagc atgaccgata aaatattctt ttgcaggagc aagtgattca tataaatgga
    32281 tccgtccatg gaagtttttc atttttccga ttttacgtcc taaattatag cgtgttcctt
    32341 ttggtaattt tttcaatcct tgagcaatca cacggatgaa ttttgaattc gtatggaatc
    32401 catacgtttg gtatcccgca aacagttcat ccgccccttc tccagattgg actacccgca
    32461 cactttgtga agcaagattt gctaaaaagt acaaaggtac gcaagaagga tttgaatcag
    32521 gttcatctaa gtgatactgg atcaaaggga atgctttgaa cgacatgtct ccgtcgatca
    32581 ctgctgctgt attatctaag tccaatagtt cggttagttt tctggcttca atcgcttcat
    32641 tataggtttt atcatcaaac ccgattgaga aagaatgatc tggtttcaat acagaggtta
    32701 cataactgga atcaaccccg ctggataaga aagaaccaac ttctacatca ctgaccgtat
    32761 gtgcttcaat agaagcttga acggtttcgt cgattttttc gatccattct tgtcgggaat
    32821 gcgtttcttt tgtttcaaaa tctgcatccc aatattgctg aatgtctatt tttccatctt
    32881 tatacgtata ataatggcct tcaggcaaac gatagacatc tttgaagaat gtttcgccgt
    32941 ttaatggaga atattggaaa gtcatataag gtttcaacgc ttctttgttc aattctttgt
    33001 taaaatcagg atgaggcaga aaacttttga tttctgaacc aaacataaat gttccgttca
    33061 tttctgcata ataatatggt ttgatcccaa agtggtctct tgcaccgaat aactcattct
    33121 tttcattatc ccaaatagca aaagcaaaca ttccgcggat cttttgcaat aattctgttc
    33181 cccattcttc gtaaccatgc aaaaggactt ctgtatctgc atgtgtttga aaaacgtggc
    33241 cagctgcaat caattcttct ctcaaaggct ggtaattata gatttcgcca ttaaaaataa
    33301 tgatctttgt ccgatcttca ttgtaaatag gctgagtacc gccctctaag tcaataatac
    33361 ttaatcttct gaatcctaaa gcaacatgtt tatcgatata ttctcctgaa ctattaggtc
    33421 cacggtgaac gattcgatcc atcattgtat taataattgt ttttttgttg tccttgtcgt
    33481 taacaaaacc tacaataccg cacatttaac tttcacatcc taatataaaa ttactgttta
    33541 tttcattcat atgcatctta tcatagaata aatagcggac gaatattttc tctcttacaa
    33601 tttcgtcacg tgaaaacaaa agatgaaagt ttctgttttt acagaaaata aagtcccaat
    33661 atctaattta ccatgttttc ttttttgagg ctaccttatt ctcttcgtgt taaaaaaata
    33721 ttagtggatg ctatttccaa aaaaaccagc aaaaaaagac acgacctaaa gatcgtgtc
//
LOCUS       DAZUJR010000026        32550 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.026, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000026 DAZUJR010000000
VERSION     DAZUJR010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32550
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.026"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(41..229)
                     /gene="rpmB"
                     /locus_tag="ACG804_001122"
     CDS             complement(41..229)
                     /gene="rpmB"
                     /locus_tag="ACG804_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HFS4832068.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            499..861
                     /locus_tag="ACG804_001123"
     CDS             499..861
                     /locus_tag="ACG804_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFS4832069.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            913..2595
                     /locus_tag="ACG804_001124"
     CDS             913..2595
                     /locus_tag="ACG804_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HFS4832070.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKETPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            2712..4748
                     /gene="recG"
                     /locus_tag="ACG804_001125"
     CDS             2712..4748
                     /gene="recG"
                     /locus_tag="ACG804_001125"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HFS4832071.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKEFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LLTGSTKAKERRELLEKLEQGEINIVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            4797..5798
                     /gene="plsX"
                     /locus_tag="ACG804_001126"
     CDS             4797..5798
                     /gene="plsX"
                     /locus_tag="ACG804_001126"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HFS4832072.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            5920..6162
                     /gene="acpP"
                     /locus_tag="ACG804_001127"
     CDS             5920..6162
                     /gene="acpP"
                     /locus_tag="ACG804_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFS4832073.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            6430..7434
                     /locus_tag="ACG804_001128"
     CDS             6430..7434
                     /locus_tag="ACG804_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4832074.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            7435..8379
                     /locus_tag="ACG804_001129"
     CDS             7435..8379
                     /locus_tag="ACG804_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4832075.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            8379..9341
                     /gene="opp4B"
                     /locus_tag="ACG804_001130"
     CDS             8379..9341
                     /gene="opp4B"
                     /locus_tag="ACG804_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HFS4832076.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            9368..10282
                     /locus_tag="ACG804_001131"
     CDS             9368..10282
                     /locus_tag="ACG804_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4832077.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            10308..12089
                     /locus_tag="ACG804_001132"
     CDS             10308..12089
                     /locus_tag="ACG804_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFS4832078.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            12437..13123
                     /gene="rnc"
                     /locus_tag="ACG804_001133"
     CDS             12437..13123
                     /gene="rnc"
                     /locus_tag="ACG804_001133"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HFS4832079.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            13143..16724
                     /gene="smc"
                     /locus_tag="ACG804_001134"
     CDS             13143..16724
                     /gene="smc"
                     /locus_tag="ACG804_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HFS4832080.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            16733..17542
                     /locus_tag="ACG804_001135"
     CDS             16733..17542
                     /locus_tag="ACG804_001135"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFS4832081.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            17553..18551
                     /gene="ftsY"
                     /locus_tag="ACG804_001136"
     CDS             17553..18551
                     /gene="ftsY"
                     /locus_tag="ACG804_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HFS4832082.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            18738..21005
                     /gene="gshAB"
                     /locus_tag="ACG804_001137"
     CDS             18738..21005
                     /gene="gshAB"
                     /locus_tag="ACG804_001137"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004357 - glutamate-cysteine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HFS4832083.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKKYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(21094..21546)
                     /locus_tag="ACG804_001138"
     CDS             complement(21094..21546)
                     /locus_tag="ACG804_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HFS4832084.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            21696..22646
                     /locus_tag="ACG804_001139"
     CDS             21696..22646
                     /locus_tag="ACG804_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFS4832085.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            22639..23598
                     /locus_tag="ACG804_001140"
     CDS             22639..23598
                     /locus_tag="ACG804_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFS4832086.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            23595..24350
                     /locus_tag="ACG804_001141"
     CDS             23595..24350
                     /locus_tag="ACG804_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4832087.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            24373..25326
                     /locus_tag="ACG804_001142"
     CDS             24373..25326
                     /locus_tag="ACG804_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HFS4832088.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(25970..26266)
                     /locus_tag="ACG804_001143"
     CDS             complement(25970..26266)
                     /locus_tag="ACG804_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HFS4832089.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            26621..26977
                     /locus_tag="ACG804_001144"
     CDS             26621..26977
                     /locus_tag="ACG804_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFS4832090.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            26987..27886
                     /locus_tag="ACG804_001145"
     CDS             26987..27886
                     /locus_tag="ACG804_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFS4832091.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            28406..29134
                     /locus_tag="ACG804_001146"
     CDS             28406..29134
                     /locus_tag="ACG804_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFS4832092.1"
                     /translation="MKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEAG
                     DEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYAA
                     ADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAVS
                     LVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSVP
                     GKSVKLAQQYSTKLVWTLEDTPNN"
     gene            29279..31306
                     /locus_tag="ACG804_001147"
     CDS             29279..31306
                     /locus_tag="ACG804_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HFS4832093.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRINIPVENQRIGTFEGKLSWILADVPGN"
     gene            31414..32511
                     /locus_tag="ACG804_001148"
     CDS             31414..32511
                     /locus_tag="ACG804_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HFS4832094.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
BASE COUNT        10860 a         5667 c         7000 g         9023 t
ORIGIN      
        1 aaaaaccgtt cactatctga acggtccaag tatcattcaa ttaaacgcgt tcaacttttc
       61 ctgatttcaa agcacgagtt gacacccaaa cttttttagg ttttccgtcg accataacgc
      121 gaactttttg taagttaggt ttaacagtac gttttgttga gttcatagcg tgtgaacggt
      181 tgtttccact ttttgtcttg cgacctgtaa agtaacaaac ttttgccatg gtaatttcct
      241 cctttgcctt gatttggagc aatagaataa ttcagctcat accagactaa catatcatat
      301 agaatggaaa tttgcaagta cattttcata gatacaattg acaattgaga agaataattg
      361 taaattaaac aaggttatac ctgaaatttt gcaaggtttt tgagtacttt gggtaactgc
      421 cttttatttc aagttgcgct atgataaaat atgatagaag aaaaatggga gttttttacc
      481 cgttaaggag gctcattcat ggctgtaaaa attcaaacgt cagctggaac cattgaaatt
      541 accaatgatg taattgcaac agttgttggt ggcgccgcga cagatgtgtt cggtgttgta
      601 ggaatggcca gcaaaaatca aattaaagat aatattactg agattttgcg taaagaaaat
      661 tactcaagag gagtagttgt ccgccaagaa gataatggta ttgctgtaga tgtttatacg
      721 attatcagct atggtacgaa aatctctgaa gtttcccgca acgtccaaga aaaagtgaaa
      781 tacaatctag aggcattatt aggcgtaact gccaattcag ttaatgtctt tgtacaaggt
      841 gttcgtgtac tgccagacta ggcaggagac tggctggtaa ctcagcagtc gatctgaagg
      901 aggattatct aggtgagtgt aacagaaata agtgcaagcc agttccagga aatggtccag
      961 gcaggtgcga atcgtctgca agtaaatgca gaatacgtca attcattaaa tgtattccct
     1021 gtgccagatg gcgatacggg aacaaatatg aatctatcta tgactagtgg agctaaggca
     1081 gtagtagatt caacctcaga aaaagtagga gaattagcag caatgctttc aaaaggattg
     1141 ctgatgggtg cgcgcggaaa ttccggcgtt attttgtctc aattgtttcg tggattttct
     1201 aagcaaattc cagatgttgt ctcattaaat gcttccgatc ttgctgcagc cttcactcat
     1261 ggagttgaaa ctgcgtataa agcagtaatg aaaccagtag aaggaacgat tttgacagta
     1321 gctagagaag cagcgaaagc tggagaaaag aaagcaaaaa gtactgatga tgtcgttgaa
     1381 gtaatgacag ctgttgtaaa aggggcaaag cgtgctttag ctaaaactcc agacttgctt
     1441 ccagtcctaa aagaagtcgg tgtcgtagac agtggagggc aaggactgct gtttgtttat
     1501 gagggctttt taagtgcatt gaatggagaa ttccaagcgg atgaaacata tgaaccttct
     1561 ccagcagaaa tggatgatat ggtcaatgca gaacatcatc gcagtgtcca aggtcaaatg
     1621 gcgacagaag atatccattt tggttactgt acagaaatca tggtaaaaat cggagaagga
     1681 cctacagtcg atagtacatt cgattacgaa gaattccgta actatttaga tggtatagga
     1741 gattctttac ttgtggtcaa tgatgacgag atcatcaaag tccacgtgca tacagaaaac
     1801 ccaggagaag tcttgaatta tggacaaaaa ttcggttcat tagtcaaaat caaagtcgac
     1861 aacatgcgct tgcagcatga gacgattttg gaacacgatg aagaagtgaa cgagtttgcg
     1921 aaaaaagaaa caccacgtat cccgtatggt atcgtagcga tcgctgctgg taaaggcgtc
     1981 caagagctgt ttgaaagttt aggcgctaat tatgttatca gtggtgggca aacaatgaat
     2041 ccaagtacgg aagacattgt taaagcgatt caagaagtaa acgcagataa agtgattgtc
     2101 ttgccaaaca ataagaacat cttcatggca gctgatcaag cagcagaagt agcagatatc
     2161 ccagtagcag ttgttccttc aagaacgatt tcccaaggat tgacagctat gctttcattc
     2221 aatgatcaag cttctttaga agaaaacaaa gaaacgatga cagaaatgtt gtctagcgtt
     2281 gtgagcggtc aagtcactca cgcgatcaga gatacctcaa ttgacggtgt agagatcaaa
     2341 gaaggagact ttttgggcat gatcgatgga aaaatcctga tctctaaccc agatatcaca
     2401 gcaacagcgt taagtacact agaacaaatg atcaatgagg acacagagat cgtaacgatc
     2461 ttggcaggtg atgaaggaac agttgaacaa gcaaatgaat ttgctgagaa actaacagaa
     2521 aaacatcctg atttggaaat cgagatccac caaggagatc agcctgtcta tccttatcta
     2581 ttttctgctg aataatttct gtgtcagaat atctttctaa cacagtattc attcataaaa
     2641 ggccttcggt tagtgatcag gtatgatcgc tgaccaagtc ctttttttgt taagggaggg
     2701 aggaaaaatt tatgcgttct ttagatgatc caatcactat gctggcagga gtcggagaaa
     2761 aaagagcagc tagtcttgcc agcttgggca tccaaacgat tgaagactta ctgacttatt
     2821 atcctttccg ctacgaagat attcaggaaa gaaatctaaa cgagatccaa gatcaagaaa
     2881 aggttacttt gaaaggaatc gtagtctcgc ctcctgtgat gaatcgattt ggttataaaa
     2941 aaagccgatt gcaatttcgt atgatgcaag aacatgatgt gttcaacgtt tcttttttta
     3001 atcaacctta tctaaaagaa aaagtcattt tatcggagga aatcgccgta tacggtaaat
     3061 gggatgcaaa gcgtaaagca ttgaacggga tgaagatttt aggttctcaa acaatggatg
     3121 acttttcgcc gatatatcac gtcaacaaat caattcgtca aacgacatta gttgatctaa
     3181 tcaaaaaagg gtttcaagaa tacggcacat tgattgaaga aaatctgcca aacaaccttg
     3241 tggagaaata tcgactgctt gaccgagctt ctgctgtaag aagtatgcat tttccaaaag
     3301 accacgaaga aaaccatcaa gccaaacgac gtgtcgtttt tgaagagttc tttttatttc
     3361 aaatgcgtct tcaaggattg aaaaaagcag aaaaagcaga aacgaatggt ttggagatcc
     3421 tttatgatgt ccaaaaattg aaagaattta ctcaaaagct accttttgaa ctgacaaatg
     3481 cacaaaaacg tgtaacgaat gaaatctgtc gggatcttcg cagtccgcag catatgcagc
     3541 gacttttgca gggagatgta ggtagcggaa aaacagtggt tgccgcgatt gcgttatacg
     3601 ctaccgttac agcaggtttc caaggtgcgt tgatggtgcc tacagaaatc ttggcacaac
     3661 aacatatgga aagcttgcaa cagctgtttg atcccaatga agtaaccatc gcattgctta
     3721 cggggtcaac gaaagcaaaa gaacgtcgtg agctccttga aaaactagag caaggggaaa
     3781 ttaacatcgt gatcggcaca catgcattga tccaagatgg agtcgaattt cagaatttag
     3841 gtctagttat tacggatgag cagcaccgtt ttggcgtgaa ccagcggaaa gtacttcgtg
     3901 aaaaaggctg gcgaccagat gtcttattta tgacagcgac tccgattcct agaacattag
     3961 ctattacagc atatggtgag atggatgtat ctatcattga tgaacttcca gctggacgta
     4021 tcccgatcga aacacgctgg gtaagaacac ctcaattgga cagtgtactg gattggacga
     4081 aaaaagaact ggcaagagga catcaaatgt atgtcatctg tccgctgatt gaagaatcag
     4141 aagcattaga tgtaaaaaat gcagtggaaa tctatgaaaa acttcgtgaa ctatttgcac
     4201 caaaatatga agttggcttg ttacatggta aaatgaagaa tcaggaaaaa gaagtaatca
     4261 tggaagcctt caaagacaac cagatgcaga tattagtttc gactactgta attgaagtag
     4321 gggtaaacgt gccgaacgcg accgtcatgc tgatcatgga tgcggatcga tttggattgg
     4381 cacagctgca tcaacttcgt ggacgtgttg gacgcggaag tgatgcttcc tactgtatct
     4441 tagttgctaa tcctaaaaat gaactaggtg tggaacggat gaaaatcatg acagagacca
     4501 ccaatggttt tgtactaagc gaaaaagatc tggaattacg tggtcctggt gaagtatttg
     4561 gcttccgtca atctggtctg cctcaatttg cgattgctga cttggtgacg gatggaaatg
     4621 ttttggaggt agccagagaa gaggctgcag ccctttggca gataaaggat tggcagatgc
     4681 ttcctgagta tcagccttta gcgcaaagcc tccaaataga aaatcaggat aatcgttatt
     4741 tcgattagca gactgtgcta tactttatac tgatgacgga aaaaggagtg gaaacaatga
     4801 aaattgccgt agatgcaatg ggcggagatc acgcacctca agcaattgta gaaggcgtgg
     4861 ctttagcgca gcaagatttt ccagaagtag aattcttact ttacggaaaa gaagcagaaa
     4921 tcaagaaata cttaacaaat gaaaaaaaca tcacgattat ccatacagac gaaaaaatca
     4981 atagtgatga tgagccagta aaagcaattc gacgaaaaaa gactgcatca atggtccttg
     5041 ctgcacaagc agtgaaaaac ggtgaagcag atgctgtatt ttcagcaggg aatacaggcg
     5101 cgctactagc agcagggttg ttcatcgtag gacgtatcaa aaatatcgaa cgccctggct
     5161 tgatgtctac cttgccagta gtagggaaag aaggtgccgg tttcgatatg ctggatcttg
     5221 gcgctaacgc agaaaacaaa ccagaacatt tgttgcaata cggtatttta ggttcttttt
     5281 atgcacgtaa agtccgaggt atcggacgtc ctcgtgtcgc actcttaaac aacggaacag
     5341 aagcaacaaa aggtagtgaa gtgacgaaaa aagcctatga actccttcag aatgaaacaa
     5401 gcttgaattt tattggaaac gtagaagctc gtgagctact caatggtgtg gctgatgtag
     5461 tggtcacaga tggatttaca ggcaacgctg ttttgaaatc tattgaagga acagcaatga
     5521 atatgatgaa tctattaaaa tctgctattc taaatgaagg gatcaaagga aaaatgggcg
     5581 ctatgctttt aaaagacggc ttacgttctt tgaaagcaga aatggattat tccaaacatg
     5641 gcggtgccgt tttgtttggc ttgaaagcac cagtcattaa aactcatgga gcaacaggcc
     5701 ccgatgctgt tcgctatacg atccgccaaa tccacacaat gcttgagaca gatgtagttg
     5761 gacaattagt cgaacaattt gaaaaaagcg aagaatagta tttggatatc tgaagcaatc
     5821 cgttccattg aaaaaaaggt ggacattcct gaaaaatgcc agtaaaatta gccatggtgt
     5881 aggtaattga caagtgtatg attcttggag gtgaaaaagt tgactcgcga agaagtattt
     5941 aacaaagtag cgaaaattat ttcaaatcat tttgagatag ataccgataa agtgacggat
     6001 gaattgaaca tcaaagatga tttaaaagct gattcaatta gtattatgga attcgtttta
     6061 gagcttgaag atgaattcgg tacggaaatt tcagatgaag acgctgaaca aattgaaaca
     6121 gtcggtggcg cagtagatta tatcagcagc catcttaaat aatttcaaat aaaagcaaag
     6181 aaggataaaa agctgcatac agctttttat ccttcttttt ttaatctttt tgacacgtaa
     6241 aagtcatttt tctgataatt ctggcgataa acagaaatta tgttgcaaag taaagcgatt
     6301 ttctatataa ttattaataa ttcattacac aaagataaga ataacctttg ttataaaacg
     6361 ctttattctg tgtaatgtcc ttttttatta agaaaaactt ccatttagga agcagagagg
     6421 ggtattcgat tgtccgataa ccaattatta gaagttcaga acctacatac aggattccga
     6481 ctcaaagatg actattacga tgcagtagat gacgtttcat ttactttaga caaaaacgag
     6541 attttagcaa tcgttgggga atctgggtgc gggaaaagta ccttggctac tacgattatg
     6601 ggattacttg atcctaataa cacaaaaatt acaggtgaga ttttatataa cgatctgaat
     6661 ttaatcgacc tgaacgaaac gctctataat aaaatccgcg gaaatgatat cggaatgatt
     6721 ttccaagatc cgttgtctgc attaaatcct ctcatgagaa tcgaagacca gatcaaagaa
     6781 ggactttcct atcacacaaa gatgaatgca gaacagcgtc aagctcgtgc actagaattg
     6841 ctagaacaag tagggattcc taatcctgcg agagttggac gccaatatcc ccatgaacta
     6901 tcaggcggta tgagacaacg tgtcatcatc gcaatcgcaa tcgcctgcaa acctccaatc
     6961 gtcattgcag atgaaccgac gacagcccta gatgtaacca tccaagcaca gattcttgat
     7021 ttactgaaag accttcagga agaaacaaaa acagggatca tcttgatcac tcatgactta
     7081 ggagtcgtag cagaaatggc tgatcgagtg gcagtgatgt atggcggaca gttcgttgaa
     7141 gtagcaggtg taaaagaact gtttgatcat cctaagcatc cttatacacg ctctttactg
     7201 aactctatac cacaagaagg aaatcatgat gcagaactcc atgtgatcga aggtgtcgtt
     7261 ccttctctga aaaacatgcc tcgtaaaggt tgtcggtttg caccacgtat tccatggata
     7321 ccagcaagcg atcatgaaga agagcctatc cttcatgaag tcgcaccgaa ccacttggta
     7381 cgttgctcct gctataagca tttccacttt agagacgaaa aaggagaggt gtagatgaca
     7441 gaattaatca caatcaaaga cctgaaagtt cattacccta ttcgcagtgg attcttcaat
     7501 cgagtaacgg atcatgtata tgctgtagat ggtgtggatt ttattatcga aaaaggaaag
     7561 acatatggtt tagtgggaga gtctggctct ggaaaatcta ctacgggaaa agccgttgtg
     7621 ggattagaaa aggtaacagc cggacaaatc atgtatgaag gaaaagatgt aacgaagcga
     7681 agcaaccgca aaaaaatggg ttataacaag gatgtgcaga tgatcttcca agattcaatg
     7741 tccagtttga atcctaaaaa gcgagtgttg gatatcattg ctgaacccat ccgaaatttt
     7801 gaacggttaa gcgatcaaga agaaaagaaa aaggtaaaag gactgctaga tatcgttggg
     7861 atgccggaag atgcgctata taaatatcct catgaatttt caggcggaca acgtcaacgt
     7921 ctaggagtag cccgtgctgt tgctaccaat ccaaaactga tcgtagccga tgaacctgta
     7981 tctgctctgg atctatctgt tcaagcgcaa gtattgaatt tcatgaaacg aatccagcaa
     8041 gaatacggcc tcagctattt attcatttca catgatttag gtgtagtaaa acacatgtgc
     8101 gacaatatcg caattatgta caaaggtcga tttgtagaaa tcggtacaag agaagacatt
     8161 tataatgacc cgcgacatat ctatacgaaa cgtctgcttt cagctattcc gcaaatcgat
     8221 gtagaaaata gggaaagcca caaagaaaat cgacgaagag tagaacaaga gtatatccaa
     8281 aaccaaaaag aatactatga tgcgactggt cgagtctacg atttgcgtac gatcacaact
     8341 acacacaaag tggcgttgaa agatggaggt gcaagctaat gtggaaaacg attctgcgac
     8401 gtgttttatt gatgatcccg caagttatta ttttaagtgt tctgatcttc ttattagccc
     8461 aagcgatgcc gggggatcca tttaccggtt tgatcaatcc aaatcaggat ccggcagtga
     8521 tcgaacagat gcgacaagca gctggcttga atgacccatg gtatgtccag tacttccgtt
     8581 ggatcggaaa tgctttgcaa ggcgattttg gtcaaagttt cttatacaaa cgctctgttg
     8641 ctgacttgat cggcgaacgg atcatcaaca ctttatatct atcgatcttg acagttgtcc
     8701 ttacttattt gattgctgtg cctctgggga tgcttgctgg ccggtatcaa aattcaatct
     8761 tggataagat tgtcgtaatc tacaacttct ttagttttgc tgttccttta tttatcttcg
     8821 gcttgatcat gctatttgtt tttggttatc gtttaggctg gttcccaaca agtggatcac
     8881 aaacactagg tttgcaaggt ggatttatca ctcaatggat agaccgtttg aaatatattc
     8941 tgttaccatc aattacccaa gcatttttgg cgactgccgt cacaatccaa tatctgcgaa
     9001 gtgaagtaat cgattcgaaa tcgctcgatt ttgtcagaac agcccgttcc aaaggggtac
     9061 cgacgaataa agtattcagt cgacatattt tccgaaatgc agcgttgccg atggcttctc
     9121 aaatggggta tgaaatcact tcgttgattg ctggttctgt agttatcgaa aagatttttg
     9181 gttatccggg agtcggaaaa ctatttattg attccatcgg ccaacgggac tataccgtga
     9241 tcacatcctt agtattgatt ttaggaatcg cgacgctagt ggggacatta ctttcagata
     9301 tcatcatgag tatcgttgac ccgcgtattc ggattcaata aaaccaatca gaaaggagaa
     9361 tggatcgatg agtgaaaaaa acaatacagc agttcaagaa agtattcctc ctatggggat
     9421 acgaatgatt gctcgagaat ttaaaaaaga taaaattgct attttttcat taggtttgct
     9481 agtggtttta ttattagtga tctttatcgg tgcgatgctg accgatcaag acaaagtgat
     9541 gtatgttagt atcttcgaca aatacgctgc accaggaaca gtttcgacac aaggacaaaa
     9601 gttcattctg ggagcagatg aaggcggacg tgatgtatta ggacaattga tcataggtgc
     9661 tagaaactct gttacgatcg gatttgcgat cacgatcctt acttcgatca tcggggttgg
     9721 attagggatc atctctggct actacggagg gatcattgac aacatcttga tgcggatcgt
     9781 tgattttatc atgattctac cgatcatgct gatcattatc gtcttcgtat cgattatttc
     9841 cagatacaat gtctggtcct ttatattcat catgagtgca ttttattggg tagctaaagc
     9901 ccgattattc cgaagcaaga cattatctga agcaagaaga gattatgtca gtgcctcaaa
     9961 aacaatggga accaatgatt ttaaaatcat gttccgcgaa atcatgccga atctaagttc
    10021 attaatcatt actaatttga cgatgaactt tgcggcaaac atcggtatcg agacaacttt
    10081 gactttctta ggtttcggct tgccggcaaa tgtacctagt ttaggtacat tgatcggtta
    10141 tgcaagtaac ggagaagtct tagtgaatcg gcaatggatc tggttacccg catcaatcct
    10201 tattttagtt ttgatgttga gtatcaatta tgttggacaa gcattcaagc gttctgcaga
    10261 tgcgcgccaa cggttaggct agtatagaag cgaaggggga aataggaatg aagaaaacga
    10321 tttttggatt tgcagcgctg atgtctgctg tcgttcttgc agcatgcggg ggcggaggta
    10381 cagatacctc tggaaacaac tctggaggca acggcaataa caaagaggaa ttaacttttc
    10441 caattgcaac aaaaaataat gatgatgcaa tcgaagacgg cgaattagaa gctgcggtcg
    10501 caacggacag tcagtttaaa ggattgttcc agtgggagtt ttaccaagat tcatatgatg
    10561 cagcttttat ggctccttct catgaaccgc tatttgcaaa cgatgacgat ttcagaatca
    10621 cagacgacgg agctgcaacg cttgatctag atgaagatac gaaaaaagcg acaatcaaag
    10681 taaaagacaa cgtcaaatgg tcagatggtg aagatgtaac ggcggacgat gtgattttcc
    10741 cttacgaaat cattgggaat aaagattaca ctggtatccg ttatgacgac actttccgta
    10801 acatcgtagg tatggaagaa tatcatgatg gaagtgccga cacaatctcc ggaatcaaaa
    10861 aaatagacga caaaacagtt gaaatcgaat ataaagaagt aaacccaagc atgcttcaat
    10921 cgggtggtgg tatctggtca tatgcagcac caaaacatac gttagaaggt gtagcaatca
    10981 aagatatgga atcaagcgat caagtacgta aaaatccagt gacttttggc ccttattaca
    11041 tgagtaatat cgttgcagga gaatcagtag aatacttgcc aaacgagcac tactggaatg
    11101 gtacgcctaa attgaaaaag atcacgatga aatctgtacc gatggcaagt gcaactgaag
    11161 cattgaactc taaattatat gatatgattt tccaaatgcc aacagatact tacgatacct
    11221 ataaagaaat tgctggctat acaaacttag gccgtgaaca aacttcttat acttatctag
    11281 gattcaagtt aggtaaatgg aatgcagata caaagagtgt ggaatacaat ccagattcaa
    11341 aaatggctga taaatcatta cgtcaagcaa tgggctatgc attagataat aatgcagtag
    11401 gtgaacgttt ctatgcaggt ttgagaagca atgcgacttc attgattcct ccagtattcc
    11461 agtcatacca tgatgatgag atgaaaggat tcacacaaga tctagacaaa gcgaaaaaac
    11521 tattagatga tgctggctac aaagatgtgg atgacgatgg tttaagagaa gacaaagatg
    11581 gaaataaact aacaatcaac tttgcttcga tgtccggtgg ggaaacagcg caaccattgg
    11641 cagattacta tatccaacaa tggaaagaaa ttggtttgga tgtccaatac acaacaggtc
    11701 gtctgatcga attcaattct ttctatgata aattagaaaa cgatgatcct gaaattgatg
    11761 tttaccaagc tgcttggaat acaggaactg atccaaatcc aagtggacta tggggaccaa
    11821 atgctgcgtt caactacact cgttatgaat cagaagaaaa tacaaaattg atcaacgata
    11881 tcagttcaag caaagcattt gatgaagagt accaaaaaga agcatatcaa aaatggcaac
    11941 aatatgcatt tgaagaagca tttgcgattc caacgttgtt ccgtaatgaa gtattgccag
    12001 tcaacgaccg tgtcaaagac tgggattggt cttatgatgt accaaaccca tgggcaaatg
    12061 tttctgttac agcagattca cgttcataat cactaaaaat gaccgaaaaa gggcgatgtc
    12121 ctttttcggt tttttgatat ttttctgttt atttctctaa tattcaggtc aaggcgctga
    12181 tttcatgact tctccaataa acggtgttca aagtccagtt tctcggtatt aagtcaaatt
    12241 tatgcaaaaa tatggaaagc cattttcaca aaattttttc ttcatactcg aaactaaacg
    12301 aatttttcac aacttctcgt caatcactag gattattaaa gctttactta ccttttgacc
    12361 gaaccatttc aaatttgaca aaaaaccagt ataataagga agtatcgaaa aaatatccat
    12421 aaaaggaatg tggaaaatgg acaaccagct gacaaaagaa ctaaaagaaa actataacat
    12481 cgtttttcac gatctaaatt tgcttgaaca agcttttacc cattcatcct atgtgaatga
    12541 gcatcgcaat ctgcaattat cggataatga gcgacttgaa tttttaggag atgccgtttt
    12601 agaactgatg gtttctcagt atttattccg tttatatcct catttgccag aaggaaaatt
    12661 gacaaaaaca cgagctgcga tcgttcgcga agacagcttg tcgaaatttg ccaaagaatg
    12721 tcactttgat caatatgttt tgttgggcaa gggagaagag aattcaggag gacgtacgcg
    12781 accagcattg ctttgcgacc tattcgaagc ttttttaggc gcgttatatc ttgaccaggg
    12841 attcgacacg acccatgcat tcatcgaaaa agtgattttt cctaaagtca aagcaggtgc
    12901 tttttcacat gagatggatc ataaaacaaa actacaagaa gtcttgcaaa aatcaggtga
    12961 tgtatcaatc gaataccgat tgatcaatga agaaggtcca gctcatgaac gagtattttg
    13021 gatcgaagtt tatgtagatg atcaattgat tggcactgga caagggaaat cgaaaaaatt
    13081 agcagaacaa gctgcggcgg aaaatgcatt ggcagcactg taaaagtaag tgagggaaag
    13141 ctttgtattt gaaacgaatt gaaatagccg gttttaaatc atttgcagac aagacagtca
    13201 ttgattttga aaatagcgtc acagcagtgg ttggaccaaa tggcagcgga aaaagcaata
    13261 ttacagaggc tatccgctgg gtattaggag aacaatctgc taaaagtctg cgaggcggaa
    13321 aaatgccgga tatcatcttt gccggttccg atacccgtaa gcagctgaat attgcagaag
    13381 tcacagtgat tttagacaat agtgatcatt atctgccatt ggagtacaat gagatcagtg
    13441 taacccgccg ttatcgacgg actggggaaa gcgagttttt catcaataaa caaagctgca
    13501 gattaaaaga tatccaagaa ttgttcttag attctggatt aggaaaagaa tcgttctcaa
    13561 tcatttctca aggaaaagta gaagcgattt tcagtagtaa accggaagac cgtcgtggga
    13621 tctttgaaga agcagctggt gtcttgaaat acaagcagcg gaaaaagaaa gcagaacaga
    13681 agctttttga aacagaagac aacctcagcc gcgtccaaga catcatccac gaattggaag
    13741 aacagttaac tcctttggcc gcccagagtg aggcagcaaa ggagttttta cggctaaaag
    13801 aaacactgac tcaaaccgat gtctctttga tggttgctga aatcaagaca gcaaaaaaag
    13861 attgggacaa caaacaagca cagcttgcga aattcaatct agaattaggc aaactatctg
    13921 agtcgatcca agaacaagaa tccattttgg cgaagcagcg taaagaaaat gcgcaagccg
    13981 atcgtctgat cgaaaaaaat cagcaagtat tattagatct ttcggaaaaa ctgaagcaga
    14041 cagaaggaca aaaagatgtt ttgcaggagc ggacaaagca tacacaaaaa agctcgcaag
    14101 aatatcaaac ttcattagca gaagcacaaa aaaaggttaa acattttgaa aagcttcaag
    14161 aaagcttgat gaaagcagca gcagaaaaag aaacagagat ccaaaaagct gaagcaaatc
    14221 tcataaaaac acagcaagaa ttagaaaaat accaaaaatc aacgaaagaa ttattggcag
    14281 aattaagaga tcaatatgtt gatttgatgc aagaacaagc agctgtagga aacgaactga
    14341 agtatctaga acgtcaatat atacaagaaa cagcaaaaag caagcagacg ttagccaagc
    14401 aatcggaagt agaagcatca gtagaccgat tgatcttaca aaaagaagaa ttgacacaaa
    14461 agcaggcgca gctaaaatca tctttaactg aaacaaaaga gaagttagaa atgatccaac
    14521 aaaacgggaa aaagttccaa gaagcattag caaaagaaca gcctaaaatg tatcaattaa
    14581 tgaatcaagt ccagcagcta cgtgctcgta agaaaagcct tcaagaaatc caagaaaact
    14641 attttggttt ttaccaaggg gttcgattgg tcttgcagca taaacagcag ctttcgggta
    14701 ttgtcggagc agtggctgaa ctgatcgatg ttcctgcaga tttcacgtta gctatcgaag
    14761 cagctttagg tggggcagcc cagcatgtca tcgttgaaaa tgaaaaagat gctcggcaag
    14821 ccatcacgta tttgaaacag caaagaggag gaagagcaac attccttcca ctgacgacaa
    14881 tcaaaccaag acaattaccg gctcatatat tgacacaagc agcagctgta gaagggttta
    14941 tagggattgc cagtgaacaa gtcagttatc ccgatcaaat ccaaactgtg gttcaaaacc
    15001 tgctaggaac gatcctttta gccaaagact taactagtgc caatgcaatc gcgcaaacga
    15061 tccgctatca atatcgagtg gtttccttag aaggtgatgt gatgaatgcc ggaggatcca
    15121 tgacaggtgg agcgaataaa cgaggaaacc aaggcagttt gtttgtacaa aatcaagaat
    15181 tgaaacagtt gactagtgaa tttgaagaag cagataaaca actccaagca caagaaaaaa
    15241 aagttcagga gctgcaacaa gaaacagctc gtttagccga agaacaagaa gttttgcgta
    15301 cacgaggcga acaattacgt tttgaagaac aagaagcgac aaatcagcta caaaacatca
    15361 taaatgaact tgaacgtttt gaaaaagaaa agcaaatctc aacttttgag acacgtgaac
    15421 tgcagcagtt tatcgaagat tacgaaaagc aaacgaacga attgaaagac aaacaaacag
    15481 atcttgaatc gcaacgacaa aaaatcgacg aagaaatcaa atcgttaagt caagaaagcg
    15541 accagatgga agccagaaga gcacaagtac aaagtcaaaa agcacaagaa caagcagatc
    15601 ttgctgtctt gaaagagcag tttaatcatc tgcagatcca gctccgcggt gcccgagtcc
    15661 aaaaagcaga ggcaaccgaa cgtcaagaag cgatagaaaa gcagttggcg acattgacag
    15721 cagacttttc tgatcatgaa gtcacagaag aaagtttgga aaaacaaatt aacgaattat
    15781 ctgctcagcg agaaacatta aaagccgagt tggcaaaagc caaagagcag cgagatagaa
    15841 ggcaaaagga gatcgataag cttgaagcag tcttggcaga gcgtaatcgt gagcaaaaag
    15901 cacgactgtc ggaacaatcc aaattagaag tccaaaaaga ccgagctgaa atgattttag
    15961 ataatcattt gacctatctg cagtcagaat atcagctgac atttgagaaa gcttcccaag
    16021 actatcaaga aacaaccgat atcgaagaca gtagaacaaa ggtttcatcc ttaaaagaac
    16081 agattgaaaa actgggacca gtaaacttaa attcaatcga acaatacgaa caagtcagtg
    16141 aaagacatac attcttagca acacagcgag atgatctgtt agcagcgaaa aaccaattgt
    16201 ttgaaacgat ggatgagatg gatgatgaag tgcggacaag attcaaagaa gtatttgaag
    16261 ctatccgtca agaattcaaa attgtctttc caaatatgtt tggcggcggt aaagctgaat
    16321 tagtactgac ggaaccaact gatttgctga aaacaggtat tgagattgaa gtacaacctc
    16381 ctggcaaaaa actgcaaagt ctaagtttgc tttctggagg agaacgagca cttacagcca
    16441 tcgcgttgct cttttccatt atccgtgtct gtcctgttcc gttttgtatc ttagatgagg
    16501 tagaagcagc gttagatgaa gccaacgtga aacgttttgg tcgttacttg agcgatttcc
    16561 aagatgacac acaatttatc gtagtcacac accgcaaagg aacgatggtc gcagcagatg
    16621 tactgtacgg agtgacgatg caggaatccg gtgtatcaaa aatcgtttct gtacggatgg
    16681 aagatatcaa tgaagaggcg aaaatcaacg aaacgaaagt gtaggaacga aaatgatcaa
    16741 attagtagca atcgatttgg acggtacatt attaaatgaa caaaagctga tttcagatga
    16801 gaataaacaa gcattagcac aagcaaaaca gcaaggggtc aagatcgttc tatgtacagg
    16861 acgcccctta gctgcgatgg cgcattatct gcaagaatta ggactggtag atgaaggtga
    16921 ctacagcatc actttcaacg gcggtttggt acaaaaaaat gatactggtg aaatcatgga
    16981 aaagaaagtg atggaagtat cagatatcca acgcttatac aaactggctc agcaattgga
    17041 tctgccacta gatgttttgt ctgacaatgt ggttttacag ctgcctagtg ccccaaggaa
    17101 gcaatccttg tacaatgtgt tgaataagct gctgcaattc caaccagcgg atataagcga
    17161 tattacagat gaatttgtgc ttaataaggc agtaatcgct tatgaccaag aagaattaga
    17221 tcctaaaatc aaagaaatac cagcagaatt ccatgaaatg tatgagatca tcaaaacaag
    17281 aagtatgctt ttggaattta tgccaaaagg tgttacaaaa gcttatggta tttctttatt
    17341 ggcaaaagat cttggtttga aacaagaaga aatcatggcg atcggtgatg aggaaaatga
    17401 tttaccgatg atccaatatg ctggactagg cgtagcgatg gagaatgctg tgcctttcgt
    17461 caaagaagca gcagatttcg tgacagccag caatgaagaa aatggcgtag ccaaagtgat
    17521 ccaaaaattt gtattagagt agggggagtc aaatgggatt ttttgataaa atcaagcgtg
    17581 cttttactgg cgaagagaaa acagaagaag ttgaagtaca ggagaagtac gacaagggtt
    17641 tagaaaagac gcgtaaaaca tttggtgaac ggatgaatga gttgtttgcc aattttcgaa
    17701 cagtcgatga agactttttt gaagaattag aagaaacact tatcggtgca gatgtaggtt
    17761 ttgaaacagc gatacgaatc accgaagcat tacgtcaaga agtgaaactc agaaatgcga
    17821 aaaaatcggc agaagtccaa aatgcgatca tcgagaaact tgtggatctc tatgaagcgg
    17881 aaggaatcaa tgaagtaaat gaactaaata tccaagaaga cggactaaca gttattttgt
    17941 ttgtcggtgt taatggtgta gggaaaacaa caagtattgg taaacttgcc catcagttca
    18001 aaaacgaagg taaaaaagta ttgatggcag cagcagatac cttccgcgct ggagcaatcg
    18061 accagttagt tgtctggggc gaacgcgctg gtgttgaagt tgttcgtggc aatgcaggag
    18121 gcgatccagc agctgtcgta ttcgatgctt tggaaagagc aaagacagag caggcagatg
    18181 ttttactagt tgatactgca ggccgactgc aaaataaagt gaacttgatg aacgaattag
    18241 aaaaaataaa acgagtaatc cagcgggaat taccagaagc accccaagaa acacttcttg
    18301 tattagatgc aaccactggt caaaacgcga tggttcaagc aaaacaattc aaagaaacaa
    18361 cagatgtgac cggtcttgtt ttgacaaaat tagatggtac agcaaagggc ggtatcgtac
    18421 ttgctatccg taatgaattg catttaccag tgaaattggt cggtcttggt gaaggaatcg
    18481 atgacttgga gccgtttgat ccaaatgatt ttgtcgttgg attgttcaaa ggattactaa
    18541 aagaagaata acccatgtct aaaaagcagg agctgtgaca aaagttgcag ctccttgttt
    18601 gaatgattgt ttttaacata gctgtgtttt tgatgccttc atttttatac ttatttgtaa
    18661 gcggttctca aacaatttcg ttctttttct tagacttttt gattataatt agattcatat
    18721 gaattggagg tcacttaatg atgaatttta agcaattatt attgcatgtc aatgcgcgcc
    18781 cttttatcga ccaagctcga tttggtatag aacgggaagg acagcgggtt gatcttgcag
    18841 gaaatctagc aaaaaccgat catccagcaa tctttggcga tcgatcctat cacccctata
    18901 tccaaacaga ttttagcgaa acacaaacag agatgatcac ccctgttacc gattctattc
    18961 ccgaattatt tcagtatctc gctgctgttt atgatgtgac tgctcgttct ataccgaaag
    19021 aagagatgat ctggccatta agtatgccac ctgccttacc ggaaaaagac gaagagatca
    19081 ttattgcaaa attaaaaaat ttcgaagatg tcttgtatcg acgttattta gcaaaaaaat
    19141 acgggaagcg aaaacagatg gtaagcggta ttcatttcaa ttttgaattt ggcgatgagt
    19201 tgctaagaac attgttcagc catcaggaag aatttcaaga tttttccgaa ttcaaaacag
    19261 aactttattt gaaaacagcg agaaacttta tgcgctatcg ctggatgatc acttatttat
    19321 tcggtgcttc accaatgagt gagaagaact actttttaga tgaatcacat ccgcaagaac
    19381 ctgttcgcag tattcgcaac agtgcgctgg gctatacgaa tcatccaaat gtgaaagttt
    19441 cctatgcttc tatgaaacag tatttagcag atatcgagcg aatgatcgaa gaagggaaac
    19501 tttcggagga gaaagaattt tatacaccgc ttcgtttccg aggcggaaag aaagtcgcag
    19561 atttagcaac aacaggtgtt cgttatattg aattgcggaa tatcgatttg aatccttatg
    19621 caagattggg tatcaatcca gagcaagttc ggttcttaca attattcctg atgtacatgt
    19681 tatggacaga agaaaaagaa gactgtgacc aatgggtagc agaaggtacg actcgaaata
    19741 acaaagtagc actagaacaa ccatcagatc aaacagaatt tcatcaagaa ggtagagaaa
    19801 ttcttgaagg aatgaagcaa atgctggttg aattggattg gttggattct ctttatttag
    19861 tagaggaagc attgactcaa atggatcatc ctgaacaaac gttagcagcg aaactctatc
    19921 aagaagcaca gctatcgagt cagcaagaag ttgctgtggc attgggacat caatattata
    19981 aagaaagcca tgaacgtccc tatcagttgg ccggttttcg cgaaatggaa ctttctactc
    20041 agatatttat gttcgatgcc atccaaaaag gtgtccaagt caaagtatta gatgagtcgg
    20101 atcaattttt gcgtctgcaa ttccaagacc atgtagaata tgtgaaaaat gcaaacatga
    20161 caagtaagga cagctatatc gtcccactta tcatggaaaa caaaacagta acgaaaaaag
    20221 tcttaaaaga agctgggttc cgggtaccag gaggcgcaga attttcatcc atggaagaag
    20281 cggtaaaagc ttatccgaga tttgccgagc aggcatttgt gatcaaacct aaatcaacca
    20341 attacgggtt aggtatcacg attttcaagg aaggagctag tctggaagat tatcaagcag
    20401 gtttagccat tgcttttcgt gaagacagtt cggttttagt agaagaattt atgccgggaa
    20461 cggaatatcg tttctttgtg atcgacggag aagtccaagc catcatgttg cgagtccctg
    20521 ctaatgttat tggtgacagt atccgaacag tgaaagaact tgttgaagaa aaaaatagtg
    20581 accctttgcg tggaacgaat catcgtgcac ctttagaatt gatccaatta ggtgaattag
    20641 aacaattgat gttgaaagaa caagggttga cgatcgaatc agttccccaa gccaatcaaa
    20701 ttgtttatct aagggagaac tcaaatatca gtacaggtgg tgattcgatc gatatgactg
    20761 atgaattttc tgaagcttac aaaaaaatcg ccgtttctgc ggtagaagca ctaggagcta
    20821 agattagtgg tatcgatttg attataccag ataaagaaat cgatcctaca actgataaaa
    20881 aagcatatgg gatcatcgaa gcaaatttca atccagccat gcatatgcat gtttatcctt
    20941 ttgcaggaaa aggcagaaga ttgacgatga atgtattgaa attgttatat cctgaagtat
    21001 tttaaaagaa aaagcttttg acagattgtc ctatttgatg tcaatctgat caaaagcttt
    21061 ttttgcatgt aaaaatttat gtgttttttc gttttaaaat aaacgatccc agaagctttt
    21121 tttctttttt ggtttttctt tttcagctgg cgaagagttt tcttctgggt attttttttc
    21181 gatatcaatc acaggttcat ttactgcttc ttttgctgtt aagagcaatc cgaattcctc
    21241 aggatttgca gtgacgtaat cgttgactac agtgaaacgg ctattgtttt tcgttgctag
    21301 ctggatatat tggttttgga cagaaagggg tagagcccca ttcaagagta tggaagcatc
    21361 tggatgtttt ttgagttctt ttaaaaagtt ttctttgttt tttggttgga tcatttcagc
    21421 aacagtcata ctaagatagc agcgttccct gaatgtccct aaatatttat gctgttcttc
    21481 agggttcact aaaggtgtac cataaagtcc cttatccaaa tggcttttta catcatcttg
    21541 tgccataaaa aataccctcc ttcttctctt tgtctttctt acgattatag catattccca
    21601 ataataccta aaacatatga aaaagcggtt gcttttgttc aacgattcac ttaaaataag
    21661 aatgaaaatc attctcaatt agaaaggtgg attggatgcg ctacggacga ctagtagcat
    21721 tattagttat tttaagtagt atttcattgt tcatcggagt atcgaatgta caattgtcag
    21781 aactgctcca gttagatggg caaagcttac aaatcttgct agtgactcgt ttgccacgaa
    21841 cgatttgttt gatccttgtg ggagcgacca gtagtatttg tgggttgatc atgcaacatt
    21901 tgacccaaaa taaatttgtt tcaccaacga ctgcgggcac gatggatagt gcgcgtttag
    21961 gtattttagt ggctatgatt ttcctacctg gtgcatcctt gattgtccga tccttgacag
    22021 cattttgctt tgcttttgca ggaacattgc tttttttatc ccttacgcga ttgttcctcc
    22081 agaaaaatca attgatgctt ccgttgattg gagtcatgtt agggaatatc attggttcag
    22141 ttgctacttt ttttgcttat caattccagt tggtacaaaa tatgacttca tggcttcaag
    22201 ggaattttgc gactgtgata cgaggaaatt atgagttatt gtatgctgtt gttccattgt
    22261 tgctcttggt ttggctattt gcttaccgat ttacgatcat tggtctgggc gaatcgtttg
    22321 cagtaaatct gggaatagat taccagaaga tgcagttttt aggcattggc ttagtatcat
    22381 tggctagtgc agtcatgttg atcatggtag gaagcattcc ttttatcgga gtgatcattc
    22441 cgaatcttgt ctctagaata tatggagatc aagtgcacaa aacaattggc gtaactgctt
    22501 tagcaggtag tttgttctta gtattttgcg atcttgtcgc tcgcgtgttg atttttcctt
    22561 atgaaatacc agtcagtgtg atcgttggaa tcatcggtgg ggctatcttc ctttatcttc
    22621 tgataagggg acgacgatat gcttaaaaaa aagccatcta tttttattgg tatgcttgtt
    22681 cttgttttat ttgttacagg aatgtacttg acgatccata catatggaaa ctggcatttt
    22741 gcatgtgcat tgaggagtaa gaaaattttt gcatttatcc ttgtctcgct agctgtcagc
    22801 agtgccacaa tcagctttca gacaattacg cataaccagt ttttgactcc ttcagtattg
    22861 ggacttgagt cgttatatgt ccttgtccaa acggtccttt tcttctttat cggaggagtg
    22921 acgatgcttc agcagacagg tacagttttt ttcttattga acgttgggct gatggtcggg
    22981 ctgagtctat tgttattttt ctttcttttg aaaaaaatga gagcgaatct ttttttatta
    23041 ctgatgtcag ggatgatttt aggtacgctt tttggtagtg tcagtacctt tttacaagtc
    23101 atcatggatc cgaatgaata tgatttgctt caaggcagat tatttgcaag ctttggcaat
    23161 atccagagtc agtatctttt gcctgcttct ttgatcatta tcggctgctg gtacctgtta
    23221 tttcgatatc gacatgtgct agacgttttc catctcggaa atgaacaagc agtaaacctc
    23281 gggatagaca cagatcgttt tgaatttttg attttatgtt gtgtcagtct tttgacaggg
    23341 acatcaacgg ctcttgtggg tccagttact tttttagggt ttattgtcgc aaatatcagt
    23401 tatcgtgtct tttctactta tcgtcatggt cagctattta tcggaagctt tctggtagct
    23461 atgctgtttc tgacaggagg acagctcgca gtagagcaga ttttcggctg gaatacaaca
    23521 gtgagtgtcg tcgttgaatt tgtcggagga atttattttg tcacaaaatt gattcgcgaa
    23581 aggaagagta tcctatgatt gatttacaaa aggtcaataa actgtaccat ggaaaatcag
    23641 tggttaaaga tgtacagtta acgattcctg aaaagaagtt gactgctttt atcggtccaa
    23701 atggtgctgg aaagtcaacg gtgttgtcga tgatcagtcg tttgatacca aaagatacag
    23761 gtgaaatcta tttagaccat aacgaagtaa aggcttggaa atccaatgaa ttagccaaaa
    23821 aattatcgat cctacgacaa tcgaatgaaa taaatgtcca aatcaccgtg aaagaattag
    23881 tagaatttgg acgatttcct tatacgaaag gaaaattgac gacaaaagac gaggaaatcg
    23941 ttcaggaatc actggaacac cttgggttag aagaaatagc ggatcaatcg attgacactc
    24001 tttcaggcgg tcaactccaa cgtgcgtata ttgcaatggt gctagcgcaa gacacggatt
    24061 atattttact ggatgaacct ttgaacaatc tagatatgaa ttttgcggtt caaatcatgc
    24121 agattttaaa aaatttagta caagaaatcg ggaaaacaat tgttattgtt cttcatgata
    24181 tcaactttgc tgcaagttat gcagacgaaa ttgttgcaat gaaagatgga cagttattta
    24241 cgcaaggaac gacccaagaa atgataaaaa aagatgtatt ggatgaatta tacgaaatgg
    24301 acatacggat ttgtgagatt gaaggccgca gattctgtct ttatttctaa aactaacatt
    24361 aggagagaag agatgaaaaa attagtagta ggtatcttga ttctagcatc atttggttta
    24421 gcagcatgtg gaaatagcaa caacaccagt caggcagaca caaaaaaaag cagcacacaa
    24481 actgaaacta cattgacgat aacagatagt aatggagacc aaatcgaggt gccaaataat
    24541 ccagaaaaag tcgtcgtatt cgacaatggt tctttagata cgatggatgc tcttggtgtt
    24601 ggagataagg tagttggagc agctacaagc agccttcctg agtatctttc atcctataaa
    24661 aaagtagaat cagcaggtgg aataaaagaa ccagacttag aaaaaattaa tcagcttcag
    24721 ccagatctaa tcatcatttc tggccgacaa agagattttc aaaaagatct aagtcaaatt
    24781 gctccgacca ttttcctttc tttagatgcg aaaaatccat gggaatcttt ccagcaaaat
    24841 gtcactgctt taggggagat ctttggtaag caagaagaag ctaaaactca attagaggaa
    24901 ttatctagtg caatcgatca gacgaaaaag aaagcagaag ctactgacaa aaaagcacta
    24961 gtcacacttg tgaatgaagg gcaattatca gcctacggat ctggttctag attcggtttc
    25021 atccatgatt tatttggctt tgaacaagca gatgatcaaa tcgaagcatc cactcacggt
    25081 caaagtgttt cttatgaata tgtgctggaa aaaaatccgg atatcttatt tgtagtagac
    25141 agaacaaaag ctattggtgg agacgacagc aaagatgata tttctgccaa tgaactggta
    25201 gcacaaacga atgctggtaa aaatcagcag atcatctccc ttgaaccaga tgtctggtat
    25261 ttaagcgggg gcggtttaga atcaatgaaa ctgatgatcg aagatgtgaa tcaagcattt
    25321 aaatagcata aataacagag gattaaactc tcatactatg taacaataat gtttcttaca
    25381 ttcttaaata gcaagagcct atcctcaaag aagttatcaa aaaccatccg taaaatcgta
    25441 ttgatgattt tacggatggt ttttatttat ttgagaaatc ttttttcaac gtgaattcat
    25501 tatctacatc atacgggttg attctagaat ggggagtggc aaaaaatagt gtgatccatt
    25561 ttttcagcat caagatcgcc tcctttgatt tgaatcaaag gtacaaagcg aaacttagat
    25621 aaaacttaaa tttagatatt tttattttgt accgatctct tctttaaacg atgttccatc
    25681 tgctgcttct cggcaataag tccactagac tagaaaatat gagaagctat tttctgtcca
    25741 gcgttcttat tactcaaaac aaatcgcagt tgtcacaatc tcttctaaac gatgttccat
    25801 ctgctgcttc tcggcaataa gcccactaga ctagaaaata tgagaagcta ttttctgtcc
    25861 agcgttctta ttactcaaag caaatcgcag ttgtcacaat ctcttctaaa caatgttcaa
    25921 tcagctgacc ttcggtatta gctcaaagca ctgatttcac aacctctatt taggcatgtg
    25981 tctcagcaag cggttgatag ttgatgatct gcatttttcg ataaaaatcg gcgggaagct
    26041 tactccaccg ttttagtaat tgatagaaat aactctcttc tgctttgatt ttatactcgc
    26101 ttaatatcaa tccaaaacta ttcgtttttt ttgaagctaa ttttttataa atatccaatg
    26161 ctttggtttt atcttcattg acaaagagtg tttttacttc aatataagaa ccctcgatat
    26221 tttgtgtttc ttcgataaaa tagatgtttt ttatatattc cttcatagtg attcctccaa
    26281 agaagtcttt tatttgataa gtttactcta ccgaagagtt gttaataatc cgtgaacaaa
    26341 aagtaattct ttttccaata gttgttaaag gttttttatt ttttatagta ttttttgtta
    26401 tttaagaaag gaataaggtt aaacaaataa caggttgctt tttgggtctt tttccgttca
    26461 agaaactgaa cgaagaaaag ggaaagttgt ctcttttgtg ataagagaaa tcataataaa
    26521 cgaatgactt actttccaat aaattgagaa cagtcagaac cagacaaatt agttgcatct
    26581 gatgaataaa gtgattattc tatgacatga ggtgatacag atgaaattag aagtgacaaa
    26641 agaagcacaa gaagtattga agaataaatt agaagcagac gatcaacttt tattagatat
    26701 cgaaaacggt gacggtccat ttgcagaaag ccaagtcagt tgccaattgg atacggcatt
    26761 tcgattgatc attgtcaaaa aagatacaca aacagatcta agtctttatt ctgtagtggc
    26821 tgatacacca gttggaccaa tcaaaatcaa agacagtgca atactttaca tggatgatcc
    26881 atccacactt gctttagaac caacttataa tagtttacaa ttaaaaggac caagcggctt
    26941 gagaaaaggc aacttgcaag ttgttcgaaa agactagagg gataaaatgg gaaaattggc
    27001 gatcatcagc gacctacatg tggacatcaa taaattcggc gaatcagagc tgatgcagct
    27061 ttggcaagtt ttgcaaaagc acaagatcac tcggcttcat ctagccggag atacggctaa
    27121 taaagtagac cgttgcctag ctgttgtcga atttttcgtc aataaaggat tatctacgac
    27181 atttcatttc ggcaatcacg agttggcaga tgtgcccaat gaacagatga tggaccattt
    27241 tccagaccca cattttttaa atgaacggta tattgcttta aatgagcaga ccgttctttt
    27301 agggatgaat ggctggtacg actatcagtt ttccgaattg aaagattacg aggcaatcgt
    27361 acgaatgaag cgtttgtatt ggtatgatcg gttcatccag cgtgggaaaa cagatctcga
    27421 ggtcaatgca gaaatgcttg cagctgcaaa aaatttgcta gaccagctgg aagcaaaaaa
    27481 acttgaggtg attttatcca ctcatttcgt tcctaaacgg gcatttatca tgtatcaatc
    27541 tgctccttat gagcgttgga acaaattaaa tgcattttta ggatcagaat cattcggaga
    27601 attacttgac cgttattcaa atatcaaaca agtagttttt ggccatacgc atcgtcgctt
    27661 tgaagataaa tccatcggtc acacgattta cagctgcaga ccttttggtt attattatga
    27721 atggcagctg acccgagatt ttgtcttgaa agaacagttg ctagacagct atgatcctat
    27781 gaaattacgt gtcctcttgc gtgcccatca cccagctttt caggcctatc aaacacaaca
    27841 tttgcaagag gaatttgaac aagcgatgac aatcgttccg tattgagaca gcattagtaa
    27901 tgtgtaaaag aaaatacctt gtaaaacata aggataagta agagcagtag atccatttat
    27961 cgtggatatg ctgctttttt tgcggaaaat aatcagcgaa tgtttatttg atcggatgat
    28021 ttgtaactcg cagagtacta gatgcaagcg tgtattcttt ttttgaacga taatcacaaa
    28081 aaaaaatata atatacattt tttatttaat tataattaat attgattgaa gtctaggcag
    28141 tcaagtcaca ttttgataga taggaggggg acttacgaat tattttaaag gctatgacag
    28201 ctgtatttct agattgtgtt tgcatcaagt tgcaataaaa actagaaatc aaatcgggct
    28261 gataatcatt tataactaat cgatacatag gaccaaatat aggtctatgt tcttttattt
    28321 cataagtatc gtaaaacaga attttgctat ggattaatcc aatcgactga tatgtttagt
    28381 aaataaagaa agaggaatgt caatgatgaa aaaagaaatc gtattaacag cagcaatgat
    28441 gttattcagc atggtagcaa gtacgacttt tgtttctgca actgaagtat acccaaagga
    28501 atataacaca gaaggaacga ttacatttga agcaggagat gagggtgtaa ctcctcctgt
    28561 tgatccagag aatcctgatc ccaataaacc tgtcgatcca tcagatcctc caagccctgg
    28621 aacaggaggg gcattatcga ttgattatgg atcaaaattc aaatttggga ctcaaaaaat
    28681 ttctactgcg gataaaacgt attatgcagc tgctgatgtg atgaacgatg ggtctagaaa
    28741 accgacatat gtccaagtga cagataggag aagtacctta tctgggtgga aattaagtgt
    28801 ctctcaacca gaacagttta aaactgccag tggggatgaa ctagttggag cacagctgaa
    28861 atttacgaaa gggcaggctg tttctttggt tgatccaaca tatacgccgc aaacggtgaa
    28921 ttctgaatta acgttgacac cgggaggaaa caatacgtta gcaattaatg ctaaatcagg
    28981 aacaggtgtg gggacttggg tctatcgatt tggtgcaaat gaaaatgaaa atcaagatgc
    29041 ggtacagctt tcggtacccg gtaaatctgt caagttagcg caacaatatt ccactaaatt
    29101 agtttggaca ttagaagata cacctaacaa ctagtttact gaaaagaact gttaaaaata
    29161 aatacgtagt catattgtct tgcgaggtaa tcgagcaaaa attgtcaaag gctaggctaa
    29221 atttgtttgg atacgaatag ttcatctagg aatttaacga tcaggaggaa aagatatatt
    29281 gaaaaagagg aggatcgtgc tcattttaag cagtctctta gtgactaata tctttccgat
    29341 catagggtac tctttggaat tgaatcagtt ggagcatgga aatagaagag acgaagaaag
    29401 caaactcact tcgacattcg acagtttaat agaatccaac cagacacaag aaagcagtga
    29461 ggatttaagt atttcgagta gtggagagac cactgacaac gtagaagctg agggttcgga
    29521 caaacaagga ctagaagatg caccaatttc tgcggttgag ctgcctgacg atcccaatat
    29581 tatttctatc gataaaattt ttcaaacacc tatcggtact agcacgtcca tattggaaaa
    29641 tgggaagtta ctgcagttga acccagcaga aaggtctcaa agaggagcta tttggtcaaa
    29701 taagaagatt agtttactct cggattttac atttaaatct tatttatact taggaaatca
    29761 acgagataga gcgggagatg gcatgacctt tacattgact ggcgatccta gaatggctag
    29821 taatcccagt caagttattg gatcgccagg tatgggaatt ggctcatatt ctactcgttc
    29881 tggccaacct tacattgcga atgcgctctc gattgagttt gatacgtata aaaatagtgg
    29941 ttcttctgat cgaatggatc gagagataac tgctgataat agagggcatg gacatgtcgc
    30001 ttttgtcacg cctaaaccaa ataataataa ttattctgga gagcatactg gcgtgacggt
    30061 agctcctaca tttctttcta atggcacatg gcgcttgtta ataattaaat gggacgcgga
    30121 gcaaagaagt cttacttatg atttggaagg tgtcggtcgc tcttctcgga ttatacctga
    30181 tctcattagg cagtttggtt ctacagaagt aaattggggg tttacttctt caacaggtac
    30241 tttttttcaa gaaaatgctg tcgctgtcac gcgacttcca tcgaatgtca catcaacagc
    30301 tgatgtaaaa gtcaacgata gtgattatgg ggccatcgct gaagctggag gaaacgataa
    30361 gataactatc agaaatacat tgaaggtcga gggggatttt cttgaatata agaaaatgca
    30421 gactagtatc gacctcccac aagaattaac tattcccgag catatcttga tcaatggaaa
    30481 tcaaattgat gccaaagata tcttgataac cggaaatcga gtcacgctaa atctgacaga
    30541 ttattttatt gctggagata cgttaataat cgaattggag acaactttgc aggaagtaat
    30601 tcctgaaaaa gtactcacta tgcattttga ataccttgaa aacgggaatt tgattgagca
    30661 atcgaatgaa ataaacctaa agatcgcaaa gctgaaggag atagatatcc atgtttatta
    30721 taaagataaa gacagtcaga ttgatattgc tgaaatgaaa acaatcactg ggaaaatagg
    30781 agagaagtat aaagaaactc ctattgatat tgaagggtat gtttttgact cggattcagc
    30841 gaatacagaa ggcatcttct ccgaaaatac agaggatatc tatttttatt acagaaaagg
    30901 caaactttat ctctcaactg ctcctcaata tgtcaatttt ggaaaacata aaatatccag
    30961 tagaccatta agtgaattcg gacagttttc aggtgggttg aaaattatag atgaacgggc
    31021 ttttggaagt tggaaattac aattgaaaca agagaaagtt cttacaaatg gagattttga
    31081 gcttccagaa gctctttcct ttgttacctc tgaaaataca acggttatag ggacatccgc
    31141 tgttacgatt ttcgaaagtg atcaaaaggg tgaaagcgat ttgtcctctc ttttagattc
    31201 tacagctcat cgtggaatca gaataaatat tcctgtagaa aaccaaagaa tcggaacctt
    31261 tgaggggaaa ctatcttgga tacttgcaga tgtcccagga aattaacagg aagagaagaa
    31321 tataacaaaa ttattgagtt tcaagaaggg cacaggtacc ataggctctt gtgtcccaca
    31381 gagacaagat tttgttatag tcttctctta catatgatta aaggagcgat tttcttgaga
    31441 ccaaaacaac aattatttat aacactccta gttattttag gggcactttt taacaatata
    31501 tcagtgtcag ctagtgcatt taatttttca gtgacgccga taacttcaga gaatcaaatc
    31561 gacaagagaa aaacttactt cgatcttcaa cttgatccgg atcaggaagt agaagtaaaa
    31621 gcggaattga gaaatgatac agaaaaagaa gtgaaaatcg atatttctgt gaatagcgca
    31681 accaccaatt caaatgtgat ggttgaatac ggaaaaaacg agattgaaaa agacatgagc
    31741 ctgatctttg atctggtaga ttatgtgagc tatccacaga tagtgacgct aaaacctaaa
    31801 agtgtccaaa ccgttgcttt tcatgtcagg atgccgaatg agcgatttga tggtgtattg
    31861 gctggtggga tcacattcca agaaatccag acggaaaagg accaaacaga aactaaggat
    31921 caaagcttat cgattgagaa tgaatacacc tatattattg ctttgttgat gcaacagaca
    31981 ctgaacgaag ttgctccgaa ccttactctt catgaagtta aaccagatca aatcaatgca
    32041 agaaatgtca tcttagcaaa cgttcaaaat gatcaaaaaa cctatatcaa tcaagtagtt
    32101 attgaaacaa aaattacaaa aaaaggacat tctgaagttt tatatcaaga ggaaaaagaa
    32161 ggattgcaga ttgcgccgaa tacaaatttt tcttttccaa ctgctttaaa tggtcaaccg
    32221 ctaaccccag gtgaatatca ccttacaatg actgttttag gaaatgaaaa tgaaaatgga
    32281 aaattttcga gaaaaaaagg aaatactacg atcaactata ccaatcaatg ggtatttgaa
    32341 aaagatttta caatagacgg aaaagtagcc aaggaattga acacgacgga tgttacgatt
    32401 aaaaaagaca ataattggat ttatatctta gtagcttcac ttttcttatt gtttatttta
    32461 ttatgcatac ttttgtttgt tttgagaaaa aaagaagaga aagaaaagta aggttaagat
    32521 aacaaatagt aaatttttat tattgtagga
//
LOCUS       DAZUJR010000027        32372 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.027, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000027 DAZUJR010000000
VERSION     DAZUJR010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32372
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.027"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..296)
                     /locus_tag="ACG804_001149"
     CDS             complement(<1..296)
                     /locus_tag="ACG804_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HFS4832095.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENEL"
     gene            complement(314..634)
                     /locus_tag="ACG804_001150"
     CDS             complement(314..634)
                     /locus_tag="ACG804_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4832096.1"
                     /translation="MITFERIKELAKKQGKSLNKVEEDLGYGKNVLYRLKNSNPSTER
                     LQEIADYFDVSVDYLLGREEKETPKHVDLSENDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            928..1068
                     /locus_tag="ACG804_001151"
     CDS             928..1068
                     /locus_tag="ACG804_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832097.1"
                     /translation="MEKTVSAKIEDLKLDILKQAKVAMEHAVDKEDSAMVAAIAEILA
                     HV"
     gene            1366..1623
                     /locus_tag="ACG804_001152"
     CDS             1366..1623
                     /locus_tag="ACG804_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="HFS4832098.1"
                     /translation="MNKEMSQTIKVQKMIDDLTHGIDSQADKIIKELQGQKVKDAKML
                     LKTINFEMNPTKRKLADVLEEKLASAINEQELLFETDTFNS"
     gene            complement(1594..1902)
                     /locus_tag="ACG804_001153"
     CDS             complement(1594..1902)
                     /locus_tag="ACG804_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832099.1"
                     /translation="MKPEFVITMLDGEKIKIFADTLVVGYDDASNIEEKDGMFYSSQI
                     YVNTLQGDIGVSTLATSRPLVGLIGFLSKATFFSLGDDIDSDETVIYKTSAVKSIGFK
                     "
     gene            1980..2726
                     /locus_tag="ACG804_001154"
     CDS             1980..2726
                     /locus_tag="ACG804_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HFS4832100.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVADVLGYSNPQKAIR
                     DHVDLEDKTQNDSFTVNGTAVVLINESGLYSLILKSKLPSAKKFKRWVTSEVLPTIRK
                     TGSYSNVPQSFAQALRLAADLEEKNQLLEQQIAEYEPKISYLDTILSSTDTVATSQIA
                     ADYGMSAIALNKLLNELGVQHKVSGQWILYRKHMNQGYTKSHTSEIPKADGGTKVVMN
                     TKWTQKGRVFIYNLLIAEGYYPQMDLEEIG"
     gene            2741..2944
                     /locus_tag="ACG804_001155"
     CDS             2741..2944
                     /locus_tag="ACG804_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4832101.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            3049..3348
                     /locus_tag="ACG804_001156"
     CDS             3049..3348
                     /locus_tag="ACG804_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832102.1"
                     /translation="MKKPTLSELIEAAEKAVKPDDWYRQSLILEKFHGMSKTTLVEYC
                     KEMETIPEFAEGILRPGHSTTFIHYHTFIWFLKWKDANKYRVKSLSPSDVLKEAS"
     gene            3348..3518
                     /locus_tag="ACG804_001157"
     CDS             3348..3518
                     /locus_tag="ACG804_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832103.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFIGLDE
                     AEYKTKKPVGRD"
     gene            complement(3577..4056)
                     /locus_tag="ACG804_001158"
     CDS             complement(3577..4056)
                     /locus_tag="ACG804_001158"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832104.1"
                     /translation="MSRKIDNIILLTTIFYLVIGATLSLLSFLSNSSLIVLNQKSILT
                     EFAHIDYFSFFKTGLICLFLSSFILYIGTTFCLMVLNLKMFIIEKWIVIIAKIFSSIS
                     IIIPMTLTFSKEQFNVATTFVSFIALFSFAVPKTFQSKSSNAKVNVENTDRKNDESY"
     gene            4101..4808
                     /locus_tag="ACG804_001159"
     CDS             4101..4808
                     /locus_tag="ACG804_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HFS4832105.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFDKKHRHVLTAIDELKEGVAEN
                     WADLFWEDTYVHPQNKQSYRIIYMNRDGFSLLAMGFTGKKALSFKLQYIEAFNKMEKE
                     LKDQLPSIPATKREMALLALAANEETNERVDAIESDLNDLKNNQLLAEPDYRTISNMV
                     RNKIRVICNQQHLNSKAKAELFKDLNGGIKRITGAVARNRIKAKQFDDVIDFINNWMP
                     STATMTIIKQMELLEDE"
     gene            4801..4929
                     /locus_tag="ACG804_001160"
     CDS             4801..4929
                     /locus_tag="ACG804_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832106.1"
                     /translation="MNRAEALKIGVIIANRWWRHNKPNILSQQHIDKQKAWQQIKK"
     gene            4987..5328
                     /locus_tag="ACG804_001161"
     CDS             4987..5328
                     /locus_tag="ACG804_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832107.1"
                     /translation="MKKELSTLDQYLTDPSWGKSNIKETSNRKIRRNLLTDEELACDQ
                     DDLGNFVSIWDHVYLIHLSRKSKKTEYIYVIEDGLIDALEEYDRDNLIDISYYGSGKK
                     YIAEMEAEFDE"
     gene            5321..6067
                     /locus_tag="ACG804_001162"
     CDS             5321..6067
                     /locus_tag="ACG804_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HFS4832108.1"
                     /translation="MSEKEQPLKNRSDNTLFNTLYKINVKDVTEKRNNLTYLSWAWAW
                     AEVSKVCEAVDYEIYHDPETYLPYVFDKKTGYMVFTSITVNGVKRDMWLPVMDGANKA
                     MKDEPYTYEVNDYQWNNETKKKEIVGKIEKRVEAATMFDINKTIMRCLVKNLAMFGLG
                     LYIFAGEDMPEDVSMLEPATQRSKKLFLDALQLVANKYEKSIDEAIVALTDAASITAD
                     DSKWTKRDLGILKRGVNWIEDQYREETKEK"
     gene            6073..6759
                     /locus_tag="ACG804_001163"
     CDS             6073..6759
                     /locus_tag="ACG804_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative HNHc nuclease"
                     /protein_id="HFS4832109.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDIGATINEEVNIDRLKTMYDGYDGD
                     RIIEVRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHNIGVINFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
     gene            6766..7599
                     /locus_tag="ACG804_001164"
     CDS             6766..7599
                     /locus_tag="ACG804_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HFS4832110.1"
                     /translation="MSDNKRYYYLKLKENFFDSDEMVLLESMPDGYIYSNILLKLYLR
                     SLKHEGKLMFNDRIPFNSTMLATITRHSVGVVEKAVQIFRDLQLIDVLDNGAIYMSDI
                     QSFIGKSSTEADRKREYRKKIEEAKRNLITGGQVSDKCPDKTTPELEIEIEKDIDIDK
                     EEKKGKYSDEHLRLAKKLQSNLTEDFPKEMNKVDIEKWADTIRLMEERDKASIEAIEY
                     VINWLPTNEFWFGNIRSAKKLREKFEKLKFEIKADKNNHKKQSQKLQYSNPSEYDDLP
                     I"
     gene            7616..8467
                     /locus_tag="ACG804_001165"
     CDS             7616..8467
                     /locus_tag="ACG804_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFS4832111.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALERAKSFVNDVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNAELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            8464..8823
                     /locus_tag="ACG804_001166"
     CDS             8464..8823
                     /locus_tag="ACG804_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HFS4832112.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELDGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCHQYQV
                     PLILAKKYRNTFKEERF"
     gene            8838..8999
                     /locus_tag="ACG804_001167"
     CDS             8838..8999
                     /locus_tag="ACG804_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HFS4832113.1"
                     /translation="MTTEEVIQMRIRSIQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            8996..9301
                     /locus_tag="ACG804_001168"
     CDS             8996..9301
                     /locus_tag="ACG804_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832114.1"
                     /translation="MSVDKKAAMKRIIELTHSENWQEDKEIVAEVQKLGKSMWTEKTR
                     RRMPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRAKNMDIDSKGRQFRYVEEK"
     gene            9301..9618
                     /locus_tag="ACG804_001169"
     CDS             9301..9618
                     /locus_tag="ACG804_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HFS4832115.1"
                     /translation="MNLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILDEYME
                     GSK"
     gene            9615..10001
                     /locus_tag="ACG804_001170"
     CDS             9615..10001
                     /locus_tag="ACG804_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HFS4832116.1"
                     /translation="MIPRFRSWYTPFKGKTIGQEMKYGQAGRLITHAEMAPDKYVLMQ
                     STGLKDKNGVEIFEGDVVLVNVSNGFDHLVNEKTVVQESEFHSGLVCKSLISGMEYRI
                     FSHQKMGYEYEVTGNIHENSELLEVE"
     gene            9998..10333
                     /locus_tag="ACG804_001171"
     CDS             9998..10333
                     /locus_tag="ACG804_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832117.1"
                     /translation="MIILATDYIDSLKDENGNVPALLNCGIKSKNRIILLRISADLAK
                     YLYLSKTAVYYTAATRYQYKGKTISQDYYDRLISPDIHGKSKSAIKLFGAIEIYADDF
                     PNLWLKEEQ"
     gene            10333..10467
                     /locus_tag="ACG804_001172"
     CDS             10333..10467
                     /locus_tag="ACG804_001172"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832118.1"
                     /translation="MKDWLEEASALVGCFINCAFISVIIALVGFVSLKVIILLWQLIF
                     "
     gene            10479..11048
                     /locus_tag="ACG804_001173"
     CDS             10479..11048
                     /locus_tag="ACG804_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HFS4832119.1"
                     /translation="MNKQEAIKKLESIKVIGNDALAACYNESINAGITLMKKIDEPKK
                     LVIPQLVAGWLEKSTDPFTKAEKIAYLIKSKDGDSYYFCDWFVRDGIVTQEQGEELLA
                     WATRQSYETLLSLYNGYEVEKEPLYSVIIAGEYLVKEISCSNEVKLVSTAYLPQYLAH
                     HYQLTEKQIKAIDERYWPFAVPVEEVAEG"
     gene            11045..11218
                     /locus_tag="ACG804_001174"
     CDS             11045..11218
                     /locus_tag="ACG804_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832120.1"
                     /translation="MSRQIMLHIPDGTKAMTITIVAAQKDGGLALKTKSIDTKQILEG
                     RDVEIEIDEEEAE"
     gene            11215..11520
                     /locus_tag="ACG804_001175"
     CDS             11215..11520
                     /locus_tag="ACG804_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832121.1"
                     /translation="MNVQVYLKRDLARFPRSWDTNSHPSEAEEEGYLMSANMIEITRD
                     DADEFDKKRSWYSVPNPMYTAVIEDYHISDRFILIDLERPKKRIKQYRRCGFSTKKW"
     gene            11544..11741
                     /locus_tag="ACG804_001176"
     CDS             11544..11741
                     /locus_tag="ACG804_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HFS4832122.1"
                     /translation="MNNRHRRVAKLRNQELNVAKVKFEREYGVSAEETYKVASQCVAD
                     ASDAIRKFGISILDIKWEDTE"
     gene            11738..11944
                     /locus_tag="ACG804_001177"
     CDS             11738..11944
                     /locus_tag="ACG804_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832123.1"
                     /translation="MKIYVVKFGNQFYRSDERSIGANTLSIVDILQSARWFDNLEEAN
                     QVSRRLGGLTQVYELVTVDHEGVE"
     gene            11944..12240
                     /locus_tag="ACG804_001178"
     CDS             11944..12240
                     /locus_tag="ACG804_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832124.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTREKPKFKVGDMVRCEA
                     EGFIYPFRGYVEKVLSNSAIIRIENTMECDKWLAKSKENLAVARLVDMEVIESK"
     gene            12316..12729
                     /locus_tag="ACG804_001179"
     CDS             12316..12729
                     /locus_tag="ACG804_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family phage packaging/lysis
                     transcriptional regulator"
                     /protein_id="HFS4832125.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGRIIAYK"
     gene            13413..13580
                     /locus_tag="ACG804_001180"
     CDS             13413..13580
                     /locus_tag="ACG804_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832126.1"
                     /translation="MYRPQYLEQKYEVITVQNGNGEIVRKYRRPIKSDTYKRKESNEV
                     IPLYGKRIAKH"
     gene            13606..13950
                     /locus_tag="ACG804_001181"
     CDS             13606..13950
                     /locus_tag="ACG804_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="HFS4832127.1"
                     /translation="MTEEFYRWLLQLIREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            13955..14236
                     /locus_tag="ACG804_001182"
     CDS             13955..14236
                     /locus_tag="ACG804_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832128.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVDIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            14339..14653
                     /locus_tag="ACG804_001183"
     CDS             14339..14653
                     /locus_tag="ACG804_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HFS4832129.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            14631..16325
                     /locus_tag="ACG804_001184"
     CDS             14631..16325
                     /locus_tag="ACG804_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HFS4832130.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            16345..17523
                     /locus_tag="ACG804_001185"
     CDS             16345..17523
                     /locus_tag="ACG804_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFS4832131.1"
                     /translation="MGIFQKAVGYFTKKATVTLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            17486..18172
                     /locus_tag="ACG804_001186"
     CDS             17486..18172
                     /locus_tag="ACG804_001186"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0046797 - viral procapsid maturation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head maturation protease, ClpP-related"
                     /protein_id="HFS4832132.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            18172..19332
                     /locus_tag="ACG804_001187"
     CDS             18172..19332
                     /locus_tag="ACG804_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFS4832133.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            19342..20217
                     /locus_tag="ACG804_001188"
     CDS             19342..20217
                     /locus_tag="ACG804_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832134.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIKIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            20214..20525
                     /locus_tag="ACG804_001189"
     CDS             20214..20525
                     /locus_tag="ACG804_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832135.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            20515..20868
                     /locus_tag="ACG804_001190"
     CDS             20515..20868
                     /locus_tag="ACG804_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HFS4832136.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            20858..21259
                     /locus_tag="ACG804_001191"
     CDS             20858..21259
                     /locus_tag="ACG804_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832137.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            21252..21656
                     /locus_tag="ACG804_001192"
     CDS             21252..21656
                     /locus_tag="ACG804_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832138.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            21668..22273
                     /locus_tag="ACG804_001193"
     CDS             21668..22273
                     /locus_tag="ACG804_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4832139.1"
                     /translation="MAKTTTVTTFDNISIKRISFNFKNATNAISTDCNGQLDGETEMQ
                     RIVKKCGSTEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDERIKSGIYSYGPDSVG
                     EDFSLAAEIVDDFEEKNKLIGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFGK
                     FYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            22293..22655
                     /locus_tag="ACG804_001194"
                     /pseudo
     CDS             22293..22655
                     /locus_tag="ACG804_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            22658..22840
                     /locus_tag="ACG804_001195"
     CDS             22658..22840
                     /locus_tag="ACG804_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832140.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            22858..26277
                     /locus_tag="ACG804_001196"
     CDS             22858..26277
                     /locus_tag="ACG804_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFS4832141.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     ATAGQSASEAEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLSKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDYAVAIGGLTAAFTLLMPIIVGFMALGGPTTL
                     IIGAVITAIAGVIAIIKNWGAITDWFKGIWSKFTDWLGGTWESIKEGASSVWDGVKET
                     WSGFVDWVQDIWQGVSDWFGELWSGLVEGASNIWQGVQETWQTFVDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWISIAWNGIVTTFHTIFDPVVAWWNGIWTSISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWNSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISGIFDNLNISIPHIPLPHFKLSGEF
                     NPLKGKIPTLGVDWYAKGSVFNSPNIIGVGEAGPEAVLPLKRSVLQEIGDRILSSTSV
                     SSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKIQNDNASAWR"
     gene            26328..27065
                     /locus_tag="ACG804_001197"
     CDS             26328..27065
                     /locus_tag="ACG804_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4832142.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVAGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINHFNCTGLSKIQIYRNGLR"
     gene            27075..29366
                     /locus_tag="ACG804_001198"
     CDS             27075..29366
                     /locus_tag="ACG804_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HFS4832143.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYSINGTNADLIVEGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKVLAKPAIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKSLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLINDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYDTAWTLDGGFNASFITAGEIVGITIRGTTLISDGTDYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNKPFLSFGAPNFR
                     YSNASYITDGDGSSLSINGSAGSSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKNFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDDGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDVRLKEDTAYDSTVLDQKRF"
     gene            29390..31471
                     /locus_tag="ACG804_001199"
     CDS             29390..31471
                     /locus_tag="ACG804_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832144.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDSVATSITSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFLAEIKGRMDSLNKQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLHVMYSNSIDFGGYDYSGNPNLMSKLKSSDFN
                     VGYHGSLTNVNGMLHFMSDGTGDIDMFTRINTPQLASGKTYTLSAKVRFDEGTTGAID
                     KLRLVYRTSPGEKILLEANSTNITTDDVGKEITIKGTANVNYQITNLDRFYISVSFSN
                     RDKINGGFKLYDIKIEEGSTATPYQPNLLDDPYWVGKTSLGKNIANKGTTFPIKSSAY
                     EIYKGNTEEELIIGQTYTITLKGTKPASQTFVAYNYWNVNFGDLKPVEGLTDVWSLTF
                     TPTKLEPGLPKDLRIFQSPKETAGACRIDWLKIEKGDTRTPNIEQYKYRGIGMRDSNN
                     PKDYVWDLEPSYVENNLATDIKVAEITGKANNYTDGKVSEINSQLTASINEVDTTAKD
                     AQTKANANATAIDELDNKIDERINDTATTTLTVTNGNTGSAKLYREGKTVSIYFVALN
                     GKRSGGNDSTILTIPEGYRPPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYG
                     SDYTFAITYTI"
     gene            31488..31637
                     /locus_tag="ACG804_001200"
     CDS             31488..31637
                     /locus_tag="ACG804_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832145.1"
                     /translation="MKAAYRPIEPYGFEQIIVNDEEHLPEECTEVEPPIPNWKPKFNY
                     WEGNK"
     gene            31634..32080
                     /locus_tag="ACG804_001201"
     CDS             31634..32080
                     /locus_tag="ACG804_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832146.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            32082..32219
                     /locus_tag="ACG804_001202"
     CDS             32082..32219
                     /locus_tag="ACG804_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HFS4832147.1"
                     /translation="MFSFSDVKMMYDWGCFTNEQVMVFVPLCITEEKADKIISKEESA
                     S"
BASE COUNT        11663 a         4896 c         6789 g         9024 t
ORIGIN      
        1 agttcgttct caatatagat atttaataaa attagaatag ctattttatc tgcttctgtt
       61 tcaaattttg agtgaaaagt tgtagaagta tcgtacaaaa ctgaaaattc aaaatgagag
      121 gcgctgaaat gtgcaagttc atgagataaa tgaaaggctt ctgcagtttc gccatataga
      181 ttttcattca aaaaaatgat tctaggcttc ggataataga agccaggctc tttcatttcc
      241 atgtaaacta ctttcaaatt gtattcgctc aacatttctt tcaatttcaa atacatacaa
      301 cccatcactc caactattca ttttcctcta aagctttagc gattgcaatc gctttacgca
      361 ttgtctcctt agatatttct tttccatcaa aagaaaaaac agtatcgttt tctgataaat
      421 ccacatgttt aggggtttct ttttcttcgc gccccagaag atagtctaca gagacatcga
      481 aatagtcagc aatttcttgc aaacgttctg tagaggggtt tgagttctta agtctatata
      541 agacgttttt accatagcct aggtcttctt caactttatt taatgatttt ccctgttttt
      601 tcgctaactc ttttattctc tcaaacgtta tcatatcaat attcctttcg ttcaagaaaa
      661 aatatttaac tttatttgtt aaaattcgtt gactatttta acaaaaggtg ttaatatcat
      721 tcttgtaaac aagtttaaca actaaaaaga caacaaaaaa cactattgat taataaatgc
      781 caaccgccaa gaaagctttt aaaatcaatg tttatatgtc ttatttaact atgttctgat
      841 tttaacactg tatgttaatt tagtcaacgc agttttttaa aaagttgtta aatttgttta
      901 cgaatataaa agaaaggaga gaagaatatg gaaaaaacag tctcggcaaa aatcgaagat
      961 ttgaaattag acatactgaa acaagcaaaa gtggcgatgg aacacgcggt agataaagaa
     1021 gactctgcca tggttgcagc catagcagag attttagctc acgtttagtc atcgttttta
     1081 cggtcttctg gaagctgacc atagataaca gcataatgaa tatctaaata agtttgaaca
     1141 atttcttttg gcgaaattga ttcgccttta gtagatactt gtgattcgtg atttagccat
     1201 gcaacaacta aatccgcagc gatttcaaac ggcgttacac tttgtgtcag ttgccataaa
     1261 gaatttcaca atatgtatgg tcgtggtaat aataccaaag agcaatttga ggaatttatg
     1321 gaaattaaaa aatacaaaaa atcatttatt aaaggaggct aaacaatgaa caaggaaatg
     1381 agccaaacaa tcaaggtaca aaaaatgata gatgatctaa cacatggaat tgatagccaa
     1441 gccgataaaa tcatcaagga attgcaagga caaaaagtta aggatgcaaa aatgcttctc
     1501 aagactatca actttgaaat gaatccaaca aaaagaaagc tcgccgatgt gttggaagaa
     1561 aagttggctt ccgctatcaa cgagcaagaa ttactatttg aaaccgatac ttttaacagc
     1621 tgatgtttta tagatgacag tttcatccga atctatatca tcgccgagag aaaagaatgt
     1681 tgcttttgac aaaaagccga taagacctac aagcggtctt gatgttgcaa gagtagatac
     1741 cccaatatca ccttgcaagg tattcacgta aatttgagaa gaatagaaca ttccatcttt
     1801 ttcttcgata tttgacgcat catcgtatcc aacgaccaaa gtatcggcaa atattttgat
     1861 tttttctcca tcaagcatag taattacaaa ttctggtttc ataaattttc acctccttaa
     1921 caattatttc agcctgtcac actgataagg aaattatacc aaagaaagga atgagaaata
     1981 tgaatacacc acaaattttt aatttcgagc aaaacgaagt tcgaactatt ttagtaaatg
     2041 atgaaccata ttttgtagga aaagatgtag cagacgttct aggatattcg aatccgcaaa
     2101 aagctattcg agatcatgtg gacttggagg ataagacgca gaacgattcg ttcaccgtca
     2161 atggaacagc agttgttttg attaacgagt caggccttta cagtttaatc ttaaaatcaa
     2221 aacttccctc tgccaaaaaa tttaaacgtt gggtaacgag tgaagtcctt ccaacaatta
     2281 gaaaaacagg tagctattca aacgtacctc aaagttttgc acaagcattg cgtttagcag
     2341 cggatttaga agaaaagaac caattactcg aacaacaaat tgccgagtac gaaccaaaga
     2401 ttagctactt agatacgatt ctttcatcga cagatacggt agctacttct caaattgcag
     2461 ctgattacgg aatgtcggca attgctctaa acaaattgct aaacgagtta ggtgttcagc
     2521 ataaagttag cggacaatgg atactttacc gaaaacatat gaaccaagga tacacaaaat
     2581 cgcacacaag tgagataccg aaagccgatg gcggcactaa agttgtaatg aataccaaat
     2641 ggacacagaa agggcgagtg tttatttaca acttattaat cgcagagggc tattaccctc
     2701 aaatggattt agaggaaatt ggttagaaag gagttttagt atgactgaca ttgcagaaat
     2761 cactcaacga gatagagaaa aaatcaaaga atatgtcgaa agttcaaagt tcttaactta
     2821 caccatgctt gctgaaagat ttggaattag caaaagctac ttatctttaa ttttaaacgg
     2881 taaaaagact tctgcagaag caaacagaat tatagattcg attatcacta tgtacgaatt
     2941 gtagagggag gtaaagtcgt tggaagataa aatcattctt acaaaatcag agcttcaaga
     3001 aatgttaaac atcgagtatg gaacgataat ttttaggagg gataataagt gaaaaaacca
     3061 acactttcag agctgataga agctgctgag aaggcagtaa aaccagacga ctggtaccga
     3121 caaagtttaa tcttggagaa gttccacggc atgtcaaaaa ctactttagt tgaatactgc
     3181 aaggaaatgg aaacaattcc tgaatttgca gaaggaatac ttcgtccagg tcactcaacc
     3241 acatttattc attaccatac ttttatttgg tttttaaagt ggaaagacgc aaacaaatat
     3301 cgtgtaaaaa gtttatcgcc ttcagatgtt ttgaaggagg caagttaatg ggcaaattca
     3361 acagagcact agtattcagc gcaccgctaa tcatctacgc tttaggcctc tggggaagca
     3421 gacaagcgtt gataggtacg attgtgtaca tggtttggat ttttataggg ctggatgaag
     3481 ctgagtacaa aacaaaaaag ccagtcggga gggactgact aaaaaagtct aatgtctata
     3541 agaaaggttt gacaataaat gaaagaatta ttttttttaa taactttcat cattttttct
     3601 atcagtgttt tctacattaa cctttgcgtt gctagatttg ctttgaaaag ttttaggaac
     3661 agcaaacgaa aatagagcta taaaagatac gaatgtagta gctacgttaa attgctcttt
     3721 agaaaacgtc aatgtcattg gaatgataat tgatatcgat gagaaaatct ttgcgataat
     3781 aactatccat ttttcaatta taaacatttt taaattaagc accattagac aaaatgtagt
     3841 tcctatatag aggataaatg aagatagaaa taaacatatt agtccagttt taaaaaaaga
     3901 gaagtaatct atgtgggcaa attctgttaa tatgcttttt tgatttaaca caatcaaact
     3961 actgttggac aaaaatgaca gtaaggaaag agttgctccg attactaaat aaaaaatagt
     4021 tgttaacaat attatattat caatttttct gctcatgttt tcaccccacc agaattatat
     4081 caaaaaggag agaagaaata atgcaagaat tagtaatttt gaaaaataaa gaagctgtga
     4141 ctacgagctt acaagttgca gaaagcttcg ataaaaagca cagacatgtt ttgacggcta
     4201 ttgatgaact aaaagagggg gttgccgaaa attgggcaga cctattttgg gaagatactt
     4261 atgttcatcc tcaaaataaa caatcatacc gaattattta tatgaataga gacggcttct
     4321 ctctattagc aatgggcttc actggtaaga aagctttaag ttttaaactt caatatattg
     4381 aggccttcaa caagatggaa aaagaattaa aagaccaatt gccatcaatt ccagcaacta
     4441 aacgagaaat ggcattactt gctctagctg caaacgaaga aacgaatgaa agagtagacg
     4501 ctatcgagtc tgatttaaac gatttgaaga acaatcaact tctagctgaa ccagattacc
     4561 gaacaatttc taatatggtt cgcaacaaaa ttagagttat ttgtaatcag cagcatttaa
     4621 atagcaaagc aaaagcagaa ttgtttaaag acttgaatgg cggaattaag cgaatcactg
     4681 gagcagtagc tagaaatcgt atcaaggcaa aacagttcga tgatgttatc gattttatta
     4741 acaattggat gccttctaca gcgacgatga caattattaa gcaaatggag ttgttagagg
     4801 atgaatagag ctgaagcgct aaaaataggc gtaataattg ctaatcgctg gtggagacac
     4861 aataaaccaa acatcctaag ccaacaacat attgataagc aaaaagcatg gcaacaaata
     4921 aaaaagtgac tcagccgacc aaagcaatga gtcacaaaga aaatacatct aaggagatgt
     4981 taccacatga aaaaagaact ttccactcta gatcaatatt tgactgatcc tagttggggc
     5041 aaatcgaata tcaaggaaac aagcaatcga aaaatcagac gtaatctttt gacggatgaa
     5101 gaactagcat gtgatcaaga cgatttggga aattttgtga gtatttggga tcatgtctat
     5161 cttatccatt tatcgaggaa gtccaaaaaa actgaatata tctatgtcat cgaagatggc
     5221 ttgattgatg cgctagaaga gtatgacaga gataacttga ttgatatctc ttattacgga
     5281 tcaggtaaga aatacattgc tgaaatggag gcagaatttg atgagtgaaa aggaacaacc
     5341 tttgaaaaat agaagtgata atacgctttt taatacctta tacaaaataa atgtgaaaga
     5401 tgttactgaa aaacgaaata acctcactta tctttcgtgg gcatgggctt gggcagaagt
     5461 tagcaaagtg tgtgaggcag tagattatga aatctatcat gatccagaaa catatctgcc
     5521 gtatgtcttt gataagaaaa caggctatat ggtttttacc agtatcacag tcaacggagt
     5581 aaagcgtgac atgtggttac cagtcatgga tggtgcaaac aaggcaatga aagatgagcc
     5641 atatacctac gaagtcaatg attatcagtg gaataacgaa acgaagaaaa aagagattgt
     5701 tggaaaaatc gaaaagcgag ttgaagcagc aactatgttt gatatcaaca aaacgatcat
     5761 gcgctgtctt gtaaaaaatc tagcaatgtt tgggctaggg ctatatatat ttgctggcga
     5821 agatatgcca gaagatgtct cgatgcttga accagctact caaagaagca aaaagctatt
     5881 cttggatgct ttacaactgg ttgctaacaa gtacgaaaaa tcaattgatg aagcaattgt
     5941 tgcattgact gatgcggctt ctataaccgc tgatgacagt aaatggacca agagagactt
     6001 gggcattcta aaacgaggcg ttaactggat tgaagatcag tacagagaag aaacaaaaga
     6061 gaagtgatat gagtgtttaa accattgatc gattcatatt cagcggttct gaaaaagttc
     6121 aaaggaaaag acataggtgc aacgatcaat gaagaagtga acattgatcg actaaagacg
     6181 atgtatgacg gatatgatgg cgatcggatt attgaagttc gatttattga tccacgtcga
     6241 tttactgtgc agcaacgaaa cttcatctat gcgctgatag gcgatatttt catcgataca
     6301 ggcatgccaa cggacttctg gaaggaattc ttttacttcc gttttgaagg cgtcacaggg
     6361 cgcaaaataa gcctcaaaga cgaatcgaat acaactgtga gtgatgctaa tgtcttagca
     6421 aatatcatct tagatttcat ctttgaacat catattcctt tcaaagaagg ctatgagatt
     6481 ttaccagcga atcaagaata ttacttctac aaatgcatca caaaaagagt ctgctgcatc
     6541 tgtggcaaaa caggagctga catcgatcac tttgacaaag cgctaggaag acgaaagcgc
     6601 aaagaagttg atcattcaga gtacacattt gcagcactct gcaggattca tcacacggag
     6661 aaacacaata taggtgtgat caatttcaaa aataaatatc aaatcaaagg gatcaagtta
     6721 aaccaggaaa caattaagaa acttagaata ggagggtaaa aaatattgtc tgacaacaaa
     6781 cgctactact atttaaaact aaaagagaat tttttcgata gtgacgagat ggttctctta
     6841 gaaagtatgc cagatggcta tatttattct aatattcttc tcaaacttta tttaagaagt
     6901 ctaaaacacg aaggtaagtt gatgtttaat gacaggattc catttaactc tacaatgctc
     6961 gcaactatta caagacattc tgtaggagtc gtagaaaaag cggtacaaat tttccgtgat
     7021 ttgcagctta ttgacgtatt agataacgga gcaatttata tgtctgatat acaaagtttc
     7081 attggaaaat cctcaactga agcagataga aaaagagaat acagaaagaa aatagaagag
     7141 gcaaaacgga atttaataac tggaggacaa gtgtcggaca aatgtccaga caaaactaca
     7201 ccagagttag agatagagat agagaaagat atagatatag ataaagaaga aaagaaaggt
     7261 aagtattctg acgaacactt acgccttgct aaaaaattgc aaagtaattt aactgaagat
     7321 tttccaaaag aaatgaacaa agtagatatc gaaaaatggg cagacacaat caggttgatg
     7381 gaagaaagag ataaagcgtc tatagaagcg attgagtatg tgatcaattg gctacctaca
     7441 aatgaatttt ggtttggaaa tattagaagt gctaagaaat tgagagaaaa atttgagaag
     7501 ctcaaattcg aaatcaaagc agacaagaat aatcataaaa agcaaagtca aaaactacag
     7561 tacagcaatc ctagtgaata tgacgacttg ccaatttaaa aaggagatgc atcacatgga
     7621 aagcctagca aatgctatgg agaaactaat aagaagagta ttagtgcaaa gcgggaaatg
     7681 tccagaatgt agcgaacctt tgtatagttg gcgagctaaa aataaggatg gttcagaacg
     7741 ttgtaaacca acatgcatga gttgtggtta taaagcgtta cgtgtgaaag aggatataca
     7801 gaccgaacgg atatataacg acagcttaaa agcacgagcg ttgagttttt ttcaaaatgg
     7861 ttcggtatta acagataaaa ctttgtttaa atgcaaaatg gagaattatc acgtagtgga
     7921 ccaagaaacg aaaattgctt tagaaagagc taaaagcttt gtaaatgatg tcttactgaa
     7981 ccatcctgca catttcattc tatcagggaa atcaggaagc ggaaaaagcc acttgtcaat
     8041 ggcgacagct tgggaaatac ttgagcgctc aaattatgac aagaaaatac tttttataag
     8101 ctatcaagag ttattagagc aaataaagtt ttcttataac aatgctgaac tgagaaaaga
     8161 aattgaagga tcgcttatag ccgatattaa aacaactgat ttggtggttt ttgacgatat
     8221 tggagctgaa ttaggtagtg gggtatcaaa tagtaggcag tttacaaaca acacgttaaa
     8281 cacgctctta gaagcaagac agaacaaggc aacgatcatc acaacaaact tatctggtcc
     8341 tgaactaaga gaagcctacg gtgaaagaat tgtttctagg atatttaaga attcagaagg
     8401 ttatgcgctg aaattccagc aaacagcaga caagcgcata aaaccagtga aaggtagtat
     8461 cgcatgaata aataccgtaa taaaaaaact gttcatcgag gtatcaagtt tgattctatc
     8521 gcagaagcag agtattacga tctagccttg tggcaagctg aagcgaatgg ctggaaagta
     8581 aaacttcagg aaagatttga gctgatgccg aaatttgaac tagacggaaa gaagtatcgc
     8641 aagatcgagt atattcccga cttcacattt tataaaaacg gcaaacttgt caaagtcgta
     8701 gatgttaaag gaatgcagac aaaagacttt aagatcaagg caaagctgtt ttgtcatcaa
     8761 tatcaagtgc cgttgatatt agctaaaaaa tatcggaata cgttcaagga agagcgtttt
     8821 taaagaggtg gtctatcatg acaacagaag aagtgattca aatgcgaatt cgaagcattc
     8881 aacgtgagat tgacgatctg gaacgaacaa aggcagtgat ggtcaatgaa acggcgagaa
     8941 aggcaatcga tttgcacata gagaacttaa gaagggaaat tcgtagattg gaggaatgag
     9001 cgtggataag aaagcagcaa tgaaacgaat catcgaactg acacattctg agaattggca
     9061 agaagacaaa gaaatagttg cagaagtcca aaagctcggt aaatcaatgt ggactgaaaa
     9121 aaccagacgg agaatgccga gaaaaattgc aatctggcac ggtgaccgaa ttctagtaac
     9181 aggtaccgct gaacagttat ctgaaattac tggtctgagc aaaaacatca tctgggatag
     9241 agcgaagaat atggatattg attctaaagg aagacagttt aggtatgtgg aggagaaata
     9301 atgaatctca ttacacaata cagtgatatc atcctcaaga aaatcatgat gaagattcag
     9361 aaagacaaaa aatcaaaaga acgagcggaa ttagttaagt tggaaatggc tgaaacaggg
     9421 gcaggagtgc gaagtagcag gcattggaag gcagcagcaa acattgaatt ttattacaac
     9481 gaaattcaaa aagggttcga tcaaatgcgt gagctggatc ggcaaacaaa ttggagcaag
     9541 aaacttcatc aagatcgttt caaatttgta gagaaatata aagagatatt agacgaatac
     9601 atggagggca gcaaatgata ccgagatttc gatcgtggta cacaccattt aaaggtaaaa
     9661 caattggaca agaaatgaaa tatgggcaag caggaaggtt gatcactcat gctgaaatgg
     9721 ctccagataa atatgtgctt atgcaatcca caggactgaa agataagaat ggcgtagaaa
     9781 tatttgaagg ggatgtagtt ctggttaatg taagtaatgg ttttgatcat ttagttaatg
     9841 aaaaaacggt tgtacaagaa tccgagtttc attccggatt agtttgtaaa tcattaatta
     9901 gtggaatgga atatagaata ttcagccacc aaaagatggg atacgaatat gaagtcaccg
     9961 gaaatataca cgagaatagc gagttattgg aggtagagtg attatcttag ctactgacta
    10021 catcgattct ttaaaagatg aaaatgggaa tgtcccagca ttgctaaatt gtggaattaa
    10081 aagtaagaat agaatcattt tgttacggat atcggctgat ttagcaaaat atctttatct
    10141 gagcaagaca gcagtatatt acactgcggc tacacgttat cagtacaagg gaaaaacaat
    10201 cagtcaggat tattatgatc gtttaatcag tcctgacata catggaaaat caaaatcagc
    10261 gatcaagtta tttggcgcaa tagagatata tgccgatgat tttccaaatt tatggttgaa
    10321 ggaggaacag taatgaaaga ctggttagaa gaagcaagcg ccttagttgg ctgtttcata
    10381 aactgtgcgt ttatatctgt aattattgca ctggtgggat ttgtatcatt gaaagtgatt
    10441 atattgcttt ggcagttaat tttttaggag gaacagcgat gaataaacag gaagcaatca
    10501 aaaagttaga aagtattaaa gtgataggaa atgatgcact agctgcttgc tataacgaga
    10561 gtataaatgc aggtattacg ttaatgaaaa aaatagacga accgaagaag ctagttattc
    10621 cacaactcgt ggccggttgg cttgagaaat ctacggaccc ttttacgaaa gctgaaaaaa
    10681 tagcgtattt aatcaaatct aaagatggtg attcatatta tttctgtgat tggtttgtac
    10741 gagatggcat agtgacgcaa gaacaaggag aagaattact cgcttgggca acgagacaat
    10801 catatgaaac actattgagc ttgtacaacg gctacgaggt cgagaaagag ccgttgtaca
    10861 gtgtaataat tgctggcgag taccttgtca aggagatcag ttgcagtaat gaagttaaac
    10921 tagtatcaac agcttacctg ccacaatacc ttgcacacca ctaccaactg accgaaaaac
    10981 agatcaaagc aattgatgaa agatactggc catttgctgt gccagtggaa gaggtggcgg
    11041 aaggatgagt agacagataa tgctccatat accagacgga acaaaggcaa tgacgattac
    11101 cattgttgct gcacaaaaag acggtgggtt ggcgttgaaa acaaaaagca ttgataccaa
    11161 acagatttta gaaggcagag atgtcgagat agagatcgat gaggaggaag cggaatgaat
    11221 gttcaagttt atttaaaaag agatttggcc aggtttcctc gaagctggga tacaaattcc
    11281 cacccatccg aggcagaaga agagggctat ctaatgtctg ctaacatgat agaaattaca
    11341 agagatgatg cggatgagtt tgataaaaaa agatcatggt actcggttcc gaatccaatg
    11401 tatacggctg taatagaaga ttatcatata tccgacagat ttattctgat tgatctagaa
    11461 aggcctaaga aacgaattaa acagtataga cgttgtggat tttcaacaaa gaaatggtga
    11521 taacaaaaca gaggtgaaga aaaatgaaca acagacaccg cagagtagca aaactaagaa
    11581 atcaagaact gaatgtagcg aaagtaaagt tcgaacggga gtatggtgtt tctgcagaag
    11641 aaacatataa agtggcaagt cagtgtgttg ctgatgcaag tgatgctatt cgtaagtttg
    11701 gaatttcgat actagatatt aaatgggagg atacagaatg aagatttatg tagtaaagtt
    11761 tggaaatcaa ttttacagaa gcgatgaacg ttctataggg gctaacacat tatccattgt
    11821 agacatactc caaagcgcaa gatggtttga taatctcgaa gaagctaacc aagtttcacg
    11881 acgacttggt ggattaacgc aagtatatga actggtcact gtcgatcatg agggggtaga
    11941 gtaatgaaac taaaagacgg attttacgct agtagtcatg gtatcggcgg tttgatgcta
    12001 gatatgccga caaagaaccc taaaacacgt gagaaaccaa aattcaaagt cggtgacatg
    12061 gttcgctgtg aagcagaagg atttatctat ccatttcgtg gatatgtaga aaaggtattg
    12121 tcgaactcag caatcattcg tattgaaaac acgatggaat gtgacaagtg gttagcgaaa
    12181 agcaaagaga atttagctgt agcgagatta gttgacatgg aagtaatcga gagcaaataa
    12241 aaaagccgga tcgctccgac taacataata aaacagacaa gtttattata tcacataaag
    12301 gagcggtttg acttgatgca attgttacga gaggtagatt tcaaacagac aagatgtaat
    12361 gcgagagatg tgctgaagaa ctttcggcgt ttggagcgga tggcaggtcg ctctttgata
    12421 gatattaagt ctccaattat tacggatatg ccgaaggcgc cgaagcacgg caataaggca
    12481 gaggacgcga tcattcagat gatggatata gaagcagaga gagatgcgat tttagcggct
    12541 ttgatggctc ttagtctgat tagccgtcag atactctact acagcttttg tgtgccagat
    12601 agcttctcaa actacagaat tagccgtgaa gtgggttatt cagaaagaag tatacaacgg
    12661 atgaagtcgg aagctctaat agagtttgca gaagcatata aacacggaag aataattgct
    12721 tataaataat ttggcggttt tttggcggaa tgatggcggt ttttagctat ttaccagtga
    12781 tattatggta gtgtcgaaag attagtgata ggtctgagac aaaataataa taaaaggaac
    12841 atcgttttat tattgtttca caattaagct tcgatagaca gcaacggaaa tattaagaat
    12901 aaggatgtga atttcaactc cttctaaatt gttcttatta tctatcatcc gttgctgtct
    12961 attgtttttt taattattca cacgataact aaaggtgagt gaagagaaat gattccatta
    13021 ataatttcaa tttttgcgct ctgtcttaat gtctatatga ttggatttaa aaatgggcaa
    13081 aataaaaaat agtagcagcc aagaataatt ttatagtgtc actgtggcgg aaagggtaga
    13141 cgcttaaaaa taaggtcaat acgtcgaggg atagccttaa cgttttatga tttgaccatg
    13201 caatgttcga ttcattgcca gtgactttgg caaccgaggg ttggaaatgg gcgctcaaag
    13261 tacacgagca aggcgaggtc gatagtaatc gatggaatcg gtgtaggttg cttgatagag
    13321 ctataactgc atctcgttta tgaggtgtag tttttacaga ttagatcact ctttgagtgg
    13381 tctttttatt ttacacaaag gaggtaacaa gaatgtatag accacaatac ttagaacaga
    13441 agtatgaagt aatcactgtg caaaacggta acggtgagat agtacgaaag tatagaagac
    13501 caataaagag cgatacatac aaacgaaagg aaagcaatga agttattcca ttgtatggca
    13561 aaagaatagc taagcattaa ataagattgc gaaaggagac ggaatatgac cgaggaattc
    13621 tatagatggc tattacagtt gataagagaa gatcgtttag ttaagttcta tcagtctcct
    13681 aaatggcgca ggcttagaga gaaagcgatg aaacgagatc actatgaatg ccaagagtgt
    13741 agaagactag gtaagtatca tagagtagaa aacgttcatc atataaagga agtcaaggat
    13801 agacctgact tagctttaga tttagataat cttatttgtt tatgtgttga acatcataat
    13861 gaagttcatg gcagatatct tacagcatta gataaacaag agaagaagat agaaagcttt
    13921 gctaacttcg atgcaagtga aaggtggtaa gtgcatgatc atcaatgata atggcagaga
    13981 gtatgataca gaaaagattg aagagtattc atcttatact cagggattaa ttaaacgttt
    14041 gatatacgtt cgctatgtag atattaggga tctgttatca gataactgtt gtagtaaata
    14101 caaagtgaat caagtaagag aagcgttgaa taaagataat aacgtcgaaa gaataaaaaa
    14161 tgtttttgga tatagtattg aagagattaa ttattacatt gacttcgctg aagctttcat
    14221 tccgatggtg agataacccc cccttaaaat aaatcgcaaa ttttttgggg gtgatgaaac
    14281 ggagggggct gtcaggaaaa gagatttttt cgaactttat catgaaagga gggctaaaat
    14341 gtttaaaaac gaattgtctc aaaatcgcta cagagaaaaa ttacgccgct ctttaataag
    14401 ccaattggaa agtcagaaaa caaatattga gccattctta gataatgttg atcgttatat
    14461 cagtttatgg gaaacggcga tatcactgga agaagatata tccgagaacg gcattagact
    14521 ggagaatggt aaaaagaatg aatcagtagc gttgcttgtt tctgtcaaca aacaaatggg
    14581 attgatgttg gataaacttg ccattactcc tgaattggta ggtgaagcaa atgaatcaat
    14641 tcctgagtta taagcatatt gaaaattggt tcaaagctat agaagaaggc actatcaagg
    14701 tatgcaaaga gcaattattg ctaaaaaatt atctagaaga aagagtcttt actagagaag
    14761 atatttactt cgataagcag atggtagagg attcaatcaa tataccagca caatactttc
    14821 cattcgaatt aattccgtgg gaaaaatttc tacaatgttt tatttatggt gttcgatgga
    14881 aaaaagataa aacactagtg ttcaatagat atctttcatt aatgggacgt ggtaatggta
    14941 aaactggttt tgcttcttgg aacaacttct ttctactaac cgctaaacac ggtattaaaa
    15001 attatgatat tgatatctat gccaataatg aaagccaagc aaagactagt tttgatgatg
    15061 tatttaaagt aattaaagat catcctgatt tagataaaaa agtatttaaa gctacgaagg
    15121 aagttattca aaatatcgct acaaacagca aacttcgtta taacacggca aatgctagaa
    15181 caaaagatgg gaagcgacca ggtgcaaacc gctttgatga aattcacgaa aatgaagatt
    15241 attcaatgat aaatgtggct acttctggtg gtggtaaaat tcgagattat agagaatttt
    15301 atgatacaac taatggtcat gttcgtggtg gtccgcttga tgacattata gaagaatcaa
    15361 aaatgattct ttctggagaa cttggaattg acaaggatgg agcagaattt tctagtttgt
    15421 ttccatttat ttgtcgcttg gataacgata atgaagttga tgatcccgac atgtgggaaa
    15481 aagcttgtcc aactattaat tacaatgcag atttaaaacg gaaaatgttt caagaatact
    15541 ctcaaatgca acgtaatgct ggtttaagac ttacgttcat gaccaaacga atgaacagac
    15601 ctatggaaga tacacgattt gctgttgctt catatgatga tgttctgcat acgaaagaaa
    15661 aagaatttcc tgaaaaaatg gatgaagtga taggaacagt cgattttgct gatagacgag
    15721 attttgccag cgttgggttg ctaggaaaat acgataaaga tgtttatttt acacaacata
    15781 cttttatcca cgaatcagcc cttcgattac aaaacatcaa acgagaggtt atagatattt
    15841 ctatagatca aggaaaatca cagatcgttc atggaaaaaa tatagaagct gattatattg
    15901 taggttggtt tcttgaaatg agtaataaat attatattaa aaaaatcgct atggatatgt
    15961 accgtgcaaa aatattgaag cccgctttag aagaagcagg ttttactgtg gaaattgttc
    16021 gaagcggatc tgttacacat ggtatgttaa aagatctggt tgatgacctt tttattaatc
    16081 aacgtttatt ttttggtgac gatgcgatta tgcgttggta ttgcatgaat gtatatgaag
    16141 agcatatttc taatggaaat atacgctatg aaaaaataga acctgaaact agaaaaacgg
    16201 atggcttttt ttcattcctt catggtttga attttttaga tgatatttat gattctgctc
    16261 ctgtaacagt cacaaatagc tcagtagaaa atacaggaac tggatttact cctctagtat
    16321 tctaacttga aaggaggtga gaaagtgggg atttttcaaa aggcggtagg atacttcaca
    16381 aaaaaagcaa cggttacttt agaagaatac ttttgtaaat tgcaagttga ttttgtgtat
    16441 cgaaaatttg cgattgaaac ttgtattgat ttgattgcaa atgcgatgag taaagcggaa
    16501 ttcaagtcat atgaagatgg aaaaaataaa aagaatgatc tttactatag gctgaatgta
    16561 gctcctaata agaaaaataa tgcaacagaa tttagaaaaa aactgatcag gagattaata
    16621 ttctacaatg aagtattgat cgtttctccg tctaataatt ctagcgaaat atttattgcg
    16681 gatagttggg atgtcacaga atatgcattg aaagatgatg tgttttctca agtgcaaatt
    16741 aacaacatag tccttgatag agaatttcta gaaagtgatg ttatctatat aaaatacgca
    16801 gatcaacaaa ttaggcaact agtcgatgcg tattatcaag cgtatgggaa actcatttct
    16861 agtgccatga atgtttacaa gcgctctaac gctcgtagat acgtactgaa agggaattta
    16921 ttccgaccgc aagacaatac aacacaagat caaatcaata aaatgatgac atcacaattt
    16981 aaggctttta tggaagctga taatgcaggt gcggtatttc aattacaaaa tgagtacaca
    17041 ttagaagatt tcagcggaaa cttccaaagc aattcaagag atataaaaaa cttaatagac
    17101 gacatctttg agatgacagc agcagcgttt cacgttccga aaaacctact aaagggagac
    17161 atgagtgggt tatcggatca agtggacgct tttttaatgt tcgaaatcat accgattgct
    17221 gaacttattc aggatgcgtt taacgctagt ctctatgaag tagaagaata cttgtcaggg
    17281 aattttgtac gtgtggatac aactatgatc aagattacta gcttcaaaga tttggttgac
    17341 gctattgatg taggcattag aaatggagta tttacaatca acgaaggaag agaacgcgtt
    17401 ggaaatgatc gctctgataa ggcgatggca gatgaaatat ttataactaa aaacaatcaa
    17461 caagtatcga aaggaggtga ggcgaatgac gacaatgaaa acatttctag cagtaaagaa
    17521 tgaaggcgca gtaccgcaaa tttttattca gggatttatt ggttctagtt ggttctttga
    17581 agggaatact gacaagggaa tcaaaaatat tttggatagt ctaggtgatc aagaagaaat
    17641 tgaagtagta attaattcaa acggtggaga cgtatttcaa gggattgcta ttgggaactt
    17701 acttaagtca aataaagcaa aagttaacgt tgtgattaac ggcttagccg ctagtgctgc
    17761 ttcaattatc gcaatggctg gcgatactat aaaaatctac aacaatgcac aattgatgat
    17821 tcaccgcgct tccacatacg gagaaggaaa tgtcgatgac ttccgtacga ttgctgacca
    17881 actggaatca attgataaat cggtaaaggc ttcatataaa acacgattca atggcacaga
    17941 tgaagcattg caagaacttc ttgaaaaaga atcgtttatg gatgcagaaa cagctttgag
    18001 ttatggattg gtcgatgaaa ttatcgatgc agaaaatagc tcaggtactg aagctaaaaa
    18061 agaacaaagc gttgaagaaa ttttgaatga cgttaaagaa aaaagagcag aaaaaattgc
    18121 tgcatttaca gcagcattaa ataaaacatt tggacaagga gatgtaaaat aatgacagtt
    18181 aaaaatttaa aaggtgtaac agctgcaagc gaccaattga tgaaagcttt taaagatggt
    18241 aacgaagaat cttttagcgc agctatggta agcttatcta aggaaattca ggataaaatt
    18301 ttagaagaag caacagcaaa aaatcaagat caattagtat taatgaaccg tggtcagcgt
    18361 gtattaacta cacaagaaac aaaattctat aacgaagtag tgaaaaacga aggttttgca
    18421 ggggtcgaag aattagtgcc agctactgta tttgaacgtg tatttgaaga tttagaacaa
    18481 tctcatccac tattgcaaaa aattactttt gttaacacaa ctggtgtaac agaatggatt
    18541 gtgtcacgtg gagtcaatcc agcatggtgg ggtaaacttt gcgaagctgt taaaaaagtt
    18601 ttagataatg gctttgatgt aattaacatg aagcagttca agctatcagg ttatattcct
    18661 gtatgtaagg caatgcttga tttaggtcca gtatggttag atcgttatgt ccgtactgtt
    18721 ttagtagaat cattgagaat tgcattagaa caagcaattg ttgatggtac tggtaaagat
    18781 atgccagtcg gaatgatgcg tgacatgagc aaacaaacta gcggagaata tgctgaaaaa
    18841 aaagcagaac ctattacagc tttagatgct gtaactatgg gcggtttgat ggcgcgacta
    18901 tcaaaattca atatcgaagg tgtgaatgat ccgatttatc gtaatgtgaa tccttctgat
    18961 gtggtcctaa ttgtgaatcc aactgattac tggtctaaag tattcccagc taagactgta
    19021 ctaactgcta atggagaata cgtacaagta ttgccagtac cagtttcaga tttgcagtca
    19081 acggctgtgc cagaaggaaa agcagttatt ggggtagcct cagattactt catgggtgta
    19141 ggatctacac taaaaattga agcttcagat gaataccatt ttgttgaaga cgaacgcatt
    19201 tatctagcta aacaatatgc aaacggtcaa cctaaacgta acgatagttt cattgtatta
    19261 gatattagcg ctttgggaac tactactaca actacaaaac caacaaccac aacaactaca
    19321 acacaagcgt aggtgatcag aatgaagtat attctttgtc agccggcaat caatcggttt
    19381 aaatgggagc ttgaagtttg tttaactaat ctgaagaaac taggaatcaa agatatcgta
    19441 ttgcttttca gcagacacga tgatcagatt cctatttttt ttgagaagga atatggtgtt
    19501 gaagttcatg tgtacgatga tctgcgggac gacaaagagt atattccttc gattaaacca
    19561 tatttatggt ggaaatattt agaagaagat cattcgcgtg aggacgaccg atatttctat
    19621 atcgattcgg atgtcatttt caataaaaga attaatttgc gcaaattgcc ttctaaagat
    19681 gatgtttggt attgtagcga ctgctgtagt tatctaagtc ttgattatat tagaagctgt
    19741 gaaaacggag aaaatattct aaaagatatg gcaaacattg taaatgttac agtagaatct
    19801 ttggaaacta taaacactaa ttcaggaggc gcacagtggg ttattaaccg ccctaaagcg
    19861 aattattgga aaaaggttta tctggattct aatcggctat atcgctacct tagagggcaa
    19921 aaaacaaata taaaaatctg gacagccgag atgtgggcac agctttggaa catgatgtat
    19981 ttcaatattg gtcctaaagt tcacgaggaa ttagactttt gttttgctac tgatccaata
    20041 gaaaaagtta aagaagtaaa aatcttacac aatgctggag taacaacaaa cgatgaagat
    20101 ttatttttca aagggagata cgtgacttct acgccttttg atgaagattt atcatttgta
    20161 aacaagaaaa aatgctctta cgcatatgtt aaagcaatta aggcggtggt tagatgacgc
    20221 ctgaacaagt gactgaagaa ttgctaatag ctgtgaagga taatatttac gttacctgga
    20281 acgaagaaga tgagtcaatt aaaaagatga tagctaaaaa tgctgtttat cttcaaagta
    20341 aagtgagtac aacactttct ttttctcctg aaagcttaga atacggattg ctaatcgaaa
    20401 gatgtagata cgactggaat cgtgctttag atgagtttga acaaaatttc gctagtgagt
    20461 tattaggttt cattcaacat tatgcgctac aagaatatat tgcaggtgat gtgaatggcg
    20521 aataatcgta gactcgaaga aacattcaac gatggttggt taaagatttt gacgcaaact
    20581 accaaaagaa atgaactagg aaaaaagatt ggtgtagaag atacagaaat cacttcttta
    20641 aaatttagaa atctttccat gagagatagt gatataacag ctatggatgc gatgggatcg
    20701 aaattaacta agaaagtaaa gactccattt catccaatcg ccaagaaatt taataaagat
    20761 caatatttta tcgtaatcga tagtatgcgt tacaacgtta tctatgccga ttacgataat
    20821 ttttatatct atttttatct tgaaagtgtg ggtgaatatg gtgattgata attctaaaga
    20881 aaaagaacgt ttaaataagc aaatttctgc tatcaaaact tccttagaag agcattttgg
    20941 cctcaaactc tttcaagact ccgtaggcga ggatgagcta cctgatgatt ttaattactt
    21001 cattctcgaa acaggagaaa tagaaatgat cactgagcca aaatatagcg tgggtcaaaa
    21061 tctatatcta actttctatt cagaaaatag agaagattta acaggagatt cactagatat
    21121 tatttcattg attcaaaatc gttcgattcg ttttcagaga atggatccca atcatttaaa
    21181 actagagaac caagatcgct atatcgatca attggtattt acgtttagac gattattgaa
    21241 gagtgattgt catggctaaa aatagttggg agctaaaaat aaatggacat gatgaacttc
    21301 ttgtgcggat ggaacgctat tcaagcgaga gcgaacgact gattaacgaa gcattgaaat
    21361 caaaaggttc ggctattgca gtggatagga ttacagaaaa aattcctgtt tctgaagcag
    21421 atttaagaag agggcaccaa cacgcaaaaa atagtcgtcc acttaagact caatacatta
    21481 atttgggttt catcattaga cctacaagaa aatttgagta tttaaaatat cctgatttgg
    21541 ggataggtac ttctaaaaga aatcagccgg acgaatttat gagaagagga ttaggtcttg
    21601 cacttgatcc aattacagaa cttctgattc gtcaattcga taaattaaat aaataggagg
    21661 aacaacaatg gctaaaacaa caacagtaac aacttttgac aatataagta ttaaaagaat
    21721 ttcttttaat tttaagaatg caacaaatgc aatttcaact gattgtaatg gacaattaga
    21781 tggcgaaaca gaaatgcaga gaattgtaaa aaaatgcggt tcaacagaag taaaatcgaa
    21841 atctaaacca atcaatatga cggtaacaat tactgcacat gtaccgatgg aagtttatcg
    21901 acgcttcaat gggttgaaac aagatgaacg tattaaatcg ggaatttact cttatggtcc
    21961 tgattccgta ggggaagatt tctctcttgc tgcagagatc gtggatgatt tcgaagaaaa
    22021 aaataagctg attggtatgt tagcatgcac ttcgaataca ggattaacat tctctattga
    22081 aaatggtgcg gatgaagtag ctgcgttaga actagaaaca aaagttatgc aagatgaatt
    22141 tggtaaattt tatcatgaag caattgttgc agaacttgaa gaagacttaa cagatcaatg
    22201 gatgacgaat ctatctgctg atgtgattaa aaaaacttca gttgtgacaa ctacggccac
    22261 tcaatcacag taaaaaaaac ggaggtagcg aaatgaacga agattactca aaaattgaac
    22321 taaacgatgg aacaattttg aatttagaac ctaaactgaa tatcaagaaa ttattgatga
    22381 tcaatagaga ttttaacaca gacgagtttg caaaaatgtc gatgggaaaa ggctctatgg
    22441 atattacagt tattcaaggt gcaaaagccg tatatgtagc ttatcgtcaa gcgaacatgg
    22501 tcgattacat ttcattcgat gaatttatag ataaatgaga ttttgatatg gaggttgcag
    22561 tagctgtata cagtactatg atgttcaaac aagcacgtga tgcctatcaa aaagaattcg
    22621 aaaaagcaaa taaggaaaaa aagcttcaaa agtaaaaatg ccaaagctct tagttgaaac
    22681 gtgggtcgat gtctattcga tgttgaccga cgttttttct atgccttcag atttggtttt
    22741 aagcgatatc tgtttagatg acattttgca aatggcttac aacaagagcg cttatgaagg
    22801 atggaagaac tatgcaataa atcaatccca gaaaaactaa aggaaaggag gtaaaaaatg
    22861 gctaaaaaga gaacggaagc agaagtaact ttcatagcta acgatgacgg attgaaatct
    22921 acgttaaaag aaatcagtgc tgaattaact aaaaatagag cagaattaaa actagaacaa
    22981 gctcaattgc aacagactgg ttctgaatca gacaagttag gaagtaaatt atcttcttta
    23041 gaaaagcagt atgaattaca aagtcaaaaa gttgaagtaa ctagccaacg tttagccaat
    23101 gcgaaaaaat attatggaga aaattccacc gaagttcaga aacttgaaag agaactgatt
    23161 aatcaacaaa cagcgcaaca acgtttgtca aacgaaattg ataaaacgag taatgcacta
    23221 gctcaagcaa aaggcgaaat acagacgtac gagtctacaa tgcaacagtt ggatagcgaa
    23281 caaaaaaatg ttcaagctag tgcttctctg attgaatccg aatacaaaaa atggcaagca
    23341 actgctggtc aatcagcttc tgaagccgag aaattagcga aagcccaaga atatgtttct
    23401 caacaatctg aaaatgcgga gaaaacgata gatatcctaa gacgacagtt agaagctaca
    23461 cagtctgaat ttggcgctac atccacagaa gcaatgcaga tggaagcgaa gcttaatgat
    23521 gctgaacgtg aatttgaaga gttaggacaa gctgctaaaa atgtagatac aactaacttg
    23581 gacgatatcg gaagcaaaat agatatgaat aatttaatgg aagcttctga cgttttaagc
    23641 gacattggcg ataagcttac agaattaggg aaacaagcag tggactctgc taacagtgta
    23701 ggtagttccc agagtaagat acaagctaat tttggtttgt ctaaacaaga ggctgaagaa
    23761 ttaacgaatg tagccagaga catttattat aaaggttttg gagaatcgtt agatcagtcc
    23821 acagatgcat tgattttggt aaagcgtaat ttaggagatt taaataatca agatttacaa
    23881 aatatcacgg aacaagctat ggtcctagaa aacaccatgg gcgctgatat ggatgaaacg
    23941 ttacgtggtg taaatggctt aatggtcaat ttcggcttga gtgctcaaga tgcaatggat
    24001 ttaatggttt cgggtactca aaacggttta gataaaacgc acgaattagg cgacaatatg
    24061 gcagaatata gccaattatg gagtcaaatg ggatattcag ctgatgaaac gttcggaatg
    24121 cttcaaaatg gtttagatgc gggtgcttat aaccttgata aagtcaatga cttagttaag
    24181 gaaatgggaa tatcgttaac agatggtcga tttgagcaaa acatggatat gtttagtgaa
    24241 agtactagaa aagcttttga agagtggaaa aatggcggag gaacacaaaa agacgttatt
    24301 aattccatga ttcaagattt tagcaatatg gatggtcaat acgaccaatt aaataaagct
    24361 tcgacaattt ggtctgcgct tggcgaagat aatgcgatga aagttgtcca atctttaact
    24421 gatgttaacc atacatttga tgatgttagt ggatctgcac aaaaaatgaa tgaagattct
    24481 actactccgt tacaagaatt aaacggaaaa atagctgaat taaaggattc attagctcct
    24541 ataggcaaca caatcataga tgcactcgaa ccagtaattg attttctagg aaagatggct
    24601 gatgcgttta ataatcttcc acaaccagta caggattatg ccgtagcgat tggcggattg
    24661 actgctgcat ttactttatt aatgccaata atagttggct tcatggctct aggtggtcct
    24721 actacattaa taataggagc agttattact gctattgctg gagttatagc aattataaaa
    24781 aactggggcg caattactga ctggtttaag ggaatatgga gtaaattcac tgattggttg
    24841 ggtggtactt gggaaagtat aaaagaaggt gcctcatcag tttgggatgg agttaaagaa
    24901 acctggtctg gatttgtaga ttgggttcaa gatatttggc aaggagtttc tgattggttt
    24961 ggagagctat ggagcggatt agttgaagga gcttccaaca tctggcaagg agtccaagaa
    25021 acttggcaaa cattcgttga ttgggtttca aatatttgga acggagtcaa agaagtatgg
    25081 tcgattattt gggcagacat tgtaggaatt gttcaaatac catggacatt aataacgtca
    25141 ttgattcaag ctggtattaa tattatcgtg ggtatttttg atgtagctgg acagttatta
    25201 ggcgcagctt ggcaagctgt ttggacacct atttctgatt tccttaaaaa tacttgggat
    25261 actatgacac aatggataag catcgcttgg aacggaattg taactacatt ccatactata
    25321 tttgatccag tagtggcatg gtggaatggt atatggacat ctattagtac tacggcttca
    25381 aatatttgga attcaattag tgcaacagct tctagtattt ggaacagtat caagaataca
    25441 atcactagct tggtacaagc agctgctaca gtaattcaaa atatttggtc aactgtatct
    25501 agttggttag gtggaatttg gaattcaatc agctctacag catcaaatat ctggaatagt
    25561 gtgactagta gtataagcaa tgctataaac gcagctaaaa gtgccattca aagtgtttgg
    25621 aatagtatat cttcgtggat cagcggaatt tggaacggta tcaaaaacac tgctttgaat
    25681 ctttggaatg gaattacaag cactattagc tctaaagtaa acgatggaaa aaatgcaatt
    25741 tcaagcggtt ggtccaatct aacaggtatt gtttccgaca tattcaataa tgttaaaagt
    25801 acaattgcta acatttggga aggtatcaaa aagactgtta gcgctccgat tgattggatt
    25861 agagataaaa tcagtggcat ctttgataat ttgaatattt cgataccaca tattccgtta
    25921 ccacatttta aattgagtgg ggaattcaat ccattgaagg gaaaaatccc aacgttgggt
    25981 gttgattggt atgcgaaagg tagtgtgttt aattctccga atattatcgg tgtcggtgaa
    26041 gcaggacctg aagcagtttt acctttgaaa agatctgttt tgcaagaaat tggtgatcgt
    26101 atcttgagta gcacatcagt ttcatctagg gcacaaacga ttcaacctgt gaataactac
    26161 gaattcaatt tcacaattga tggtaacgca gatgaggtta ctatgaagca aacaactcaa
    26221 caaatcattg atagcattac aaaaattcaa aatgataatg cttcggcatg gcgttaaaca
    26281 ggagagtatt tctcctgttt ttttagtatt aaaaaggatg tgaaaaaatg actgattgta
    26341 tacattctat aatcgatgga tttcctgatt atttgcataa attggcttta gctgaaagac
    26401 caaccatacc ttctccaaaa agacagagag ttgaaacttc tgttttaggt aggttaggtg
    26461 gcttagtaca agattactcg tttgaagata tgtcgtttac attgcactat aactatttag
    26521 aggatgtgga agaccatcaa gcgttcaagc aatcgtttta tatcatgcgt cattggttaa
    26581 actatgcaaa gaaattagaa ttctctgacg atcccaacgt ctattacgtt atccagacta
    26641 tcgatattgg ggatgcagaa aacgatattg ttgaatgggg agagttcgat gtaaatatta
    26701 ctgcgaaacc attcgcaaga gttcaagaag atgtacctat aaccgtagat aaaccacagt
    26761 catttaactt gctgaataat agtttagaag aaagttttcc aaagattatc atcactcctt
    26821 cagctacttc atgccagttc atcttaaatg attatgtgtt tagtttcgaa ggcttagtag
    26881 caggaactga tgtagtcatt gatagtgatt tgatgctttg ctacgaagag caatcggacg
    26941 gagatatttt agatcggtcc aacaaaatga agaccatgca atatccaacg ttgcaagtgg
    27001 atattaatca ttttaattgt actggtttga gcaaaataca aatttatcgt aacgggttaa
    27061 ggtaggtgaa atagatgatc gataatttaa taactattta cgataaaaat gacgcgaata
    27121 atttagctga acatttatat gatacgcaag gtttaggcgc tttgtcagac tggttaacag
    27181 ctactgttag caataaacta aacggagccg agatatttca gggtacttat tcaataaacg
    27241 gaactaatgc agatttgatt gtagaaggac gtattattca gtgttatgta gatgaaaatc
    27301 gagcaaaaca gcgtctacgg atttattatg caaaaacttc tgtaataggc aatacgatag
    27361 aagtaaaagc tgaacctatt ttcaatgata taagaaaatc ggtgttgaat aaatatgaca
    27421 gcggaacaga aaagatcact gctactcagg catggcaaaa cgcaaaagtt ttagcgaaac
    27481 cagctatccc ttcgcagttt tctttctcgt cattagtaga tacgcttgct aatgtgaaga
    27541 tagaaaaggc gaatttttta gaattctttg gtggaaaaga gggatctatt ctagatcgat
    27601 ttcatggtga gtttctaaaa gataataaca cattacgtca tgaaaaaagt ctaggtacgg
    27661 atcataaaat caaagcgatt tatactaaaa acttaactgg tcttgactta gagattgatg
    27721 ctcaaagtgt tttagttgga gtttatccat tcattagcag ctcttcagaa ggagaagacg
    27781 agatcactct accagaagaa gttattttca cggattacgt ggatgattat cctgctggat
    27841 atgtttcttt tgttgatttt aaagacaaag cgactgatgt agccacatta agggaagctg
    27901 ctaaagactg gttgaaaaca aacatagata aacaaaaacc acaagtgagt ggttcgattg
    27961 aattagtacc attgaggcat caaagaggct atgaaaaatt tgttgatcta gaaaaagttt
    28021 cgatgggtga cggagtagat gtgtatcatc cacagttaaa agtgaatatg tcagcgagaa
    28081 ttgtggaata tacgtttaat gttctaacca attcatacga taaattagtt gtaggaaacg
    28141 tcaaaacaaa cttcttagaa aacacagaga ataatgtcag caatttgatt aatgatgcca
    28201 ttgatcaatt gaaaaatggt ggcgaaatca gtgatttaat caatgatatt gtagatcatc
    28261 aaactgatat gattactggt caaaatggtg gttacgtttt attagatcct aaagaagccc
    28321 ctagtcgtat tttgattatg gacacaccag ataagaatac tgcacggaac gttttgcaaa
    28381 tcaacaacgc tggtattggt ttctctaaaa ctggcattaa tggaacgtat gacaccgcat
    28441 ggacgttaga tggcggattc aatgcctcgt ttattacagc tggtgagata gtagggatta
    28501 ctattagagg tactacatta attagtgatg gcactgatta tagaacaagt atagctaatg
    28561 gcaaaatgac ttggtactca aaaaaagtta acaaagatat tatggagcta gaagcacgtg
    28621 attatgtaag tgctgatgca ggtattgtat catacaccat gaaaactggt ggtggtttca
    28681 tgattagaaa tccacagggg aatttggttt ttagtacgtg ggataatggt aataacaaac
    28741 cgtttttatc ttttggtgcg cccaatttca ggtatagcaa tgctagttat ataactgatg
    28801 gcgatggtag ttctttaagc attaatggta gtgcgggcag ttcatgggag tttaaagtag
    28861 ctggtaggac tatgaaattt actagtgatg gtatgctaac gttgccaggt tgtttttttg
    28921 gttcatggga agatggaaaa cttgctaggt ttgaacaatc aacggtacaa gtatataaaa
    28981 attttactgt tagaggtact aaaaactcaa ccgtaccaac agaacattat ggacaacgac
    29041 tattaaacgc ttatgaaact ccagaatatt atttcgctga ttatggggaa gccgttacag
    29101 gtgatgatgg taaagttcgt gttgatattg atcctatgtt tgccgagaca gtaaatctaa
    29161 gtcgatatat gacacatgtg acacctacag agctagtttt gtgtgctgtt actcatgaag
    29221 atattgacca tttcatcatt gaaactagta agccaaacgt attggttaga tggaatttag
    29281 tggcacatcg actagggtat gaagatgtta gattaaaaga ggatacagca tatgatagca
    29341 cagtgcttga ccaaaaacgt ttttaaaacg aagacaagga ggtatataaa tggctagcag
    29401 tttatataat ttggctttag atttcagcaa agaattaaac tacaccaaag ctattatggc
    29461 tcgtcaaggt gacaaaggaa ttacggtgac tgttaaaccg tttttaaatg gcttgcagat
    29521 ggatacgagt ggcggaacct ttacattaaa aggaacaaca ccatctaacc gttacgtaga
    29581 tagtgtcgct actagtataa ctagcgaaga agtcacattt tctcttgatg gaacatttat
    29641 gagtgaagca ggatactata aacactgcta cgtagaatat agaaaagata atcaaatttt
    29701 aacgacgcaa gatatcattt ttttctcact aggagtgtct gacatttcgc aaggccaagc
    29761 cgatgaatat gtttcgcaat tagaagaatt gattcgaaag tataacgaaa cttttgatgc
    29821 ttttctggct gaaattaaag gtagaatgga tagcttaaat aaacagatta ctgatttaac
    29881 tggtcaagct aaaacactac aagacaagtt agatgctctg aaagaagaaa tttctaaatt
    29941 aggtaactta catgtgatgt actccaacag catcgacttc gggggctatg attatagtgg
    30001 gaatccgaat ttaatgtcca aactaaaatc gagcgatttt aacgttggtt accacgggtc
    30061 actaactaat gttaacggaa tgttacattt tatgtctgat ggtacagggg acattgatat
    30121 gtttacgcgt attaatacac ctcagcttgc tagtgggaaa acctatactc tgagtgcgaa
    30181 agttcgattt gatgaaggaa ctacaggagc tattgataaa ttacgtttgg tgtatcgtac
    30241 atcaccagga gaaaagatat tattggaagc aaatagtaca aatattacaa cagatgatgt
    30301 agggaaagaa ataacaatca aaggtacagc taacgttaat tatcaaatca caaatttaga
    30361 tcgattttat attagtgtta gtttttctaa cagggataaa ataaatggtg gatttaaatt
    30421 gtacgacatc aaaatcgaag aaggctcaac agccactccg tatcagccaa acttactaga
    30481 tgacccttac tgggtaggta aaacatcgtt gggtaagaat attgcaaata aaggtacgac
    30541 gttcccaatt aaatctagcg cgtacgaaat atataaaggt aacacggaag aagagcttat
    30601 aataggtcaa acgtatacta tcacgcttaa aggaacaaaa cccgcaagtc aaacctttgt
    30661 agcatataat tattggaacg ttaattttgg agatctaaaa ccagttgagg gattgacaga
    30721 cgtatggtct ctaacattca caccaacgaa acttgaaccg ggtttgccta aagaccttcg
    30781 catttttcag tcgcctaaag aaacggccgg cgcatgccga attgactggc tcaagatcga
    30841 aaaaggcgac acacgaaccc cgaatattga gcaatataaa taccgaggaa tcggcatgcg
    30901 agactcaaac aatccaaaag attatgtatg ggatctagaa cctagctatg ttgagaataa
    30961 cctagctaca gatatcaagg ttgctgaaat cacaggtaaa gcaaacaatt ataccgatgg
    31021 gaaagtatcg gagattaatt cgcagttgac tgcttcaatt aatgaagtag acaccacagc
    31081 taaggatgct caaacaaaag cgaatgctaa tgcgactgct atagatgaat tagacaataa
    31141 gatcgatgaa cgcattaatg atacagctac taccacatta acagttacaa acgggaatac
    31201 cggatcagca aagctttatc gtgaaggaaa aacagtttct atatattttg tggctttaaa
    31261 cggaaaacgc agtggtggaa atgattcaac gatactaaca attccagaag gctatcggcc
    31321 accaattagt tttgagcaac tggttggctc gatagaccgt tctactttga acagtgctca
    31381 gttatctatt ggtgcagatg gagccattaa atggcgaaga aactcaagtt atggatcgga
    31441 ttataccttt gcaattactt acacgattta gaaaagcgtg aatcgatatg aaggcagcat
    31501 atagaccaat tgaaccttac ggattcgagc aaatcattgt gaatgatgaa gaacatttac
    31561 cggaagaatg cacagaagtc gaaccaccga ttccaaattg gaaaccgaaa ttcaattact
    31621 gggagggaaa taaatgaaaa acatttggaa atatggacgt actggcggag agtacgcagg
    31681 aaaagtattg gacgacatgc ttgtatccgt tccttacaca gatcagccac cgcttgaagg
    31741 aattcgtgct gatggcgaac cgttaacaat cgctgatcaa atgtttgatc ctaaattgaa
    31801 tcaatggatt attttagcga acgcactaga tcacaacgat ttaaacaatc tcaaagcaat
    31861 gtatgagtcg ttagaaaatg agaacggcga tttaaaacag atcaatgcca aactcatgct
    31921 aagcgatgta gcaattaaac aggaaaatac tgcattgaaa gaaaaagcgg atagtttagc
    31981 acaaatcaat tcaaaaatga tgcttgcttc gttacaaaat agcaaagaca tttcagaaat
    32041 taaagagcaa ctaaatccag cttcaaaggg aggtgagtag tatgtttagt tttagcgatg
    32101 tgaaaatgat gtatgattgg ggctgtttca ctaacgaaca agtaatggtt ttcgttccgt
    32161 tgtgcattac tgaagaaaaa gcagataaaa tcattagcaa agaagagagc gcatcttaat
    32221 tgatgtgctt tttattttga ttcaaggagt tgtcacatga ttaatttagg ggaatgggga
    32281 gcgatagcag gatcaataac cgctatcgtt tctttgattt tattagtaat aaaaccaatt
    32341 actgcatctt tctcgaagat tactgagact ct
//
LOCUS       DAZUJR010000028        30798 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.028, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000028 DAZUJR010000000
VERSION     DAZUJR010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30798
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.028"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(51..3704)
                     /gene="rpoC"
                     /locus_tag="ACG804_001203"
     CDS             complement(51..3704)
                     /gene="rpoC"
                     /locus_tag="ACG804_001203"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HFS4832148.1"
                     /translation="MIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYRTLKPERE
                     GLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVS
                     HIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTEREYREKRE
                     QYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLDILEAFRA
                     SGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNA
                     PGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKNAKRKIER
                     QEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVCEAYNADF
                     DGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTMEEEG
                     REGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMITTVGKII
                     FNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKKKNLGNII
                     AEVFKRFKVKETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIENAHKQVET
                     ITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSGARGNISN
                     FTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTRKEVRHPE
                     TNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNLATGSDVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNPKGQAVIT
                     EVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGAPLTEGSI
                     DPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRVMDPGDTD
                     ILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAASFQETTRV
                     LTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVYSISDIEA
                     QMAAEDAMNNQTK"
     gene            complement(3783..7400)
                     /gene="rpoB"
                     /locus_tag="ACG804_001204"
     CDS             complement(3783..7400)
                     /gene="rpoB"
                     /locus_tag="ACG804_001204"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFS4832149.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLFALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            8128..9096
                     /locus_tag="ACG804_001205"
     CDS             8128..9096
                     /locus_tag="ACG804_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFS4832150.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            9114..10019
                     /locus_tag="ACG804_001206"
     CDS             9114..10019
                     /locus_tag="ACG804_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4832151.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGSAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            10016..10822
                     /locus_tag="ACG804_001207"
     CDS             10016..10822
                     /locus_tag="ACG804_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4832152.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            10979..11947
                     /locus_tag="ACG804_001208"
     CDS             10979..11947
                     /locus_tag="ACG804_001208"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004077 - biotin-[acetyl-CoA-carboxylase]
                     ligase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HFS4832153.1"
                     /translation="MTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKAIKELEKA
                     GYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMMTSESTMKDAKLAAAQGD
                     SVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTIIAASACVK
                     AIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLNFSVPQNH
                     FPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKSFVLGKTV
                     SFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(12264..12788)
                     /locus_tag="ACG804_001209"
     CDS             complement(12264..12788)
                     /locus_tag="ACG804_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HFS4832154.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            13075..14829
                     /gene="scm"
                     /locus_tag="ACG804_001210"
     CDS             13075..14829
                     /gene="scm"
                     /locus_tag="ACG804_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HFS4832155.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSTSSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDT
                     SASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTS
                     ASSDSTDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSS
                     TTSDTRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVI
                     LLVIGLRITFMSYKKSKR"
     gene            complement(14984..15970)
                     /locus_tag="ACG804_001211"
     CDS             complement(14984..15970)
                     /locus_tag="ACG804_001211"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HFS4832156.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(15993..16559)
                     /locus_tag="ACG804_001212"
     CDS             complement(15993..16559)
                     /locus_tag="ACG804_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HFS4832157.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(16573..16989)
                     /locus_tag="ACG804_001213"
     CDS             complement(16573..16989)
                     /locus_tag="ACG804_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HFS4832158.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(17446..19380)
                     /locus_tag="ACG804_001214"
     CDS             complement(17446..19380)
                     /locus_tag="ACG804_001214"
                     /EC_number="1.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFS4832159.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            19682..20617
                     /gene="pplA"
                     /locus_tag="ACG804_001215"
     CDS             19682..20617
                     /gene="pplA"
                     /locus_tag="ACG804_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular electron transfer flavoprotein
                     PplA"
                     /protein_id="HFS4832160.1"
                     /translation="MKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSESSTAQSST
                     AKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKYDNVNENG
                     ESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSSESFQNYA
                     QQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGKVTESNFD
                     YIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPANVEVVTGA
                     THSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            20707..21810
                     /locus_tag="ACG804_001216"
     CDS             20707..21810
                     /locus_tag="ACG804_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HFS4832161.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            21823..22776
                     /gene="menA"
                     /locus_tag="ACG804_001217"
     CDS             21823..22776
                     /gene="menA"
                     /locus_tag="ACG804_001217"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HFS4832162.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(23590..24936)
                     /gene="gor"
                     /locus_tag="ACG804_001218"
     CDS             complement(23590..24936)
                     /gene="gor"
                     /locus_tag="ACG804_001218"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HFS4832163.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(25070..26323)
                     /locus_tag="ACG804_001219"
     CDS             complement(25070..26323)
                     /locus_tag="ACG804_001219"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1901576 - obsolete organic substance
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HFS4832164.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(26329..27252)
                     /locus_tag="ACG804_001220"
     CDS             complement(26329..27252)
                     /locus_tag="ACG804_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HFS4832165.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(27473..29965)
                     /locus_tag="ACG804_001221"
     CDS             complement(27473..29965)
                     /locus_tag="ACG804_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HFS4832166.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(29972..30439)
                     /locus_tag="ACG804_001222"
     CDS             complement(29972..30439)
                     /locus_tag="ACG804_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HFS4832167.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(30575..30648)
                     /locus_tag="ACG804_001223"
     tRNA            complement(30575..30648)
                     /locus_tag="ACG804_001223"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(30612..30614),aa:Arg,seq:acg)
     gene            complement(30706..30779)
                     /locus_tag="ACG804_001224"
     tRNA            complement(30706..30779)
                     /locus_tag="ACG804_001224"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(30743..30745),aa:Pro,seq:tgg)
BASE COUNT         8934 a         6557 c         5749 g         9558 t
ORIGIN      
        1 caaaaaagag gttgtgacaa taatttgtca caacctcttt tttaaaatat ctattttgtt
       61 tgattgttca ttgcgtcttc tgcagccatt tgcgcttcaa tatctgaaat actgtagaca
      121 ttttcgcttg ctacaccgac ttcttttggt tccatgtcac gataacgttg cataccagta
      181 ccagctggga tgatcttacc tataataaca ttttctttca aaccaagaag aggatctttc
      241 ttaccgcgga tcgcagcatc cgtcaagaca cgagttgttt cttggaatga tgcagcagat
      301 aagaaactat ttgtttctaa tgatgctttt gtgataccta gtaagacagg tcgagaagtt
      361 gcaggaacgc ctcctgagac tagcgtattg tagttttgat ctttaaagtc tgcgatgtct
      421 aataatgtac ctggtaagat atctgtatca cctggatcca ttacacgaac tttacgcagc
      481 atttgacgaa ccattacttc gatatgcttg tcgccgattt ctaccccttg catacggtaa
      541 acacgttgta cttcacgaag caagtagttt tcaacagata atacatcgcg aacttgcaac
      601 aattgttttg gatcgattga tccttctgtc aatggtgcac cacggtggat catatcgcct
      661 tctgctactt tcatacgtgc tgtataagga acagtatacg tacgtgtatc tgtttttcct
      721 ttgattgtta cttctttggt acgtgttgca ggatcttctg agatatcgat gacatcccct
      781 gttacttctg tgatcactgc ttgccctttc ggattacgtg cttcaaagat ttcttggaca
      841 cgaggaagac cttgagtgat atcgtctccg gcaaccccac ctgtatggaa tgtacgcatc
      901 gtcaactgag taccaggttc accgattgat tgagcggcga tcgtaccaac tgcttctccg
      961 acttcaacgt cagagccagt tgcaaggttg cgtccgtaac aatgtttgca gacaccatgt
     1021 tttgtattac atgtgaagac agaacggatt gtcactgttt cgacacctgc atcaacgatt
     1081 tgttttgcga tgtcttcgga aatcaattgg tttcctgcaa tgatcaattc atttgtttca
     1141 ggatgacgta cttctttacg ggtgtaacgt cccactaaac gatcttctaa tgattcgatg
     1201 atttcatttc cctcgcggat ggcttggatt tcaagacctc ggtcagtacc gcaatcttct
     1261 tcacggatga ttacatcttg ggccacgtca accagacgac gagtcaagta acctgaatcg
     1321 gcagtcttca aggctgtatc ggtcatccct ttacgagccc cgtgagttga gataaacatt
     1381 tccaagacgg atagtccttc acggaagttc gaaatgattg gcaattccat gattcgacca
     1441 ttaggagcgg ccatcaaacc acgcattccg gcaagctgtg taaagttgga aatgttacca
     1501 cgagctccag aatcagacat catgaagatt ggatttttcg cttccaaacc ttccatcagt
     1561 ttttgttgga tgctgtcttt tgcagcattc caaacagcaa tgacacgttc ataacgttcg
     1621 tcatctgtga tcagaccacg acggaattgt tttgtaatag tttcaacttg tttatgggca
     1681 ttttcaatga tttcttgttt ttcattcagt acactgatgt cagcgatccc tactgtgata
     1741 ccggcatgtg tcgaatgttt gtaccctaag tctttcatac ggtcaagcat cttagaagtt
     1801 tcttttactt tgaatcgttt gaagacttct gcgatgatgt ttcctaagtt tttcttcttg
     1861 aacggtaata ctaattcttg ctctttgata tgtgcaggaa tatcagtacc agcttcaaca
     1921 aagtatttgt ccggtgtttg gacggtcaag ttgaagtctg ttggttcatt cagataaggg
     1981 aattcaggag gcatgatctc gttgaagatg atcttaccaa ctgttgtgat catcgtacgt
     2041 tctttttgcc attcagtaaa tggtttttca cctaatgagt tagggttcac accgatacgt
     2101 gaatgtaaat gaacatatcc gttgcgccat gcgataacgg cttcgttttg atctctgaag
     2161 accattcctt cgccttcgcg tccttcttct tccattgtca agtagtagtt acctagaacc
     2221 atatcttgag aaggagtaac aactggttta ccatctttag ggttcaagat gttttgagca
     2281 gctaacatca acatacgtgc ttctgcttgt gcttcttcat tcaatggaac gtggacagcc
     2341 atttggtctc catcgaaatc ggcattataa gcttcacata caagtggatg caaacggatt
     2401 gcgcgtcctt gtactaaaac tggttcgaat gcttggatac caagtcggtg aagcgtaggt
     2461 gcccggttca gcaatactgg gtgttccttg attacgtctt ctaaaacatc ccatacttcg
     2521 tcttcttgac gttcgatttt acgtttcgca tttttgatgt ttgaagctag ttcgcgttga
     2581 acaagctcac gcatcacgaa tggtttgaat aattcaatgg ccatttcttt tggaagtcca
     2641 cattggtaca tcttcaagaa aggtccaaca acgataacgg aacgacctga gtagtcgaca
     2701 cgtttaccta gcaagttttg acggaaacga ccttgtttcc ctttcaacat atgagaaaga
     2761 gatttcaatg ggcggttacc tggtccagta actggacgtc cgcgacgacc gttatcgatc
     2821 aatgcatcta ctgcttcttg cagcatacgt ttttcatttt gaacgatgat tccaggtgca
     2881 ttcaagtcta acaaacgttt caaacggtta ttacggttga ttacacgacg gtaaagatca
     2941 ttcaagtcac ttgttgcaaa acgtccacct tctaattgaa ccattgggcg taaatctggt
     3001 ggaataacag ggataacgtc cataaccatc cagcttggtt gatttcctga agcgcggaat
     3061 gcttctaaaa tatccaaacg gcggattgca cgtgtacgtt tttgtccttg tgcagatttc
     3121 aattcttctt tcaattcggc tgcttctgca tctagatcaa cattatcaag taattgttta
     3181 atcgcttctg cacccatagc agcttggaat tcttgtccat attgttcacg tttttcgcga
     3241 tattcgcgtt ctgtcaacaa ttgttttttc tctaaattcg tatttcctgg ttcgatgact
     3301 acatatgaag caaaataaat gatttcttcc aaagcgcgtg ggctcatgtc taatacaaga
     3361 cccatacgtg aaggaatccc tttaaagtac cagatatgtg aaacaggagc tgctaattca
     3421 atatgtccca tgcgttcacg gcgaactttc gaacgagtaa cttccactcc gcatcgatca
     3481 caaacgattc ctttataacg gatacgtttg tattttccgc aggcacattc ccagtctttt
     3541 gtaggaccaa aaatccgctc acagaacaac ccttcgcgtt caggttttaa ggtacgatag
     3601 ttaatcgtct caggtttttt tacttcaccg taagaccagc ttctgatttt ttcgggagaa
     3661 gccaaaccta tttgcatact ttcgaattta tttacatcga tcaaaagggg ttccctccat
     3721 ttcatttaat ggcaaaccgc aagacggctg atcttcgacc gccttgcagc tcatagaccg
     3781 gattagtcta aattatcttc tgcggtttca aagttttgga tgacatcgtc tttttcatct
     3841 tccacttgtt cagcagcttt cttttctaat tctttggcag tttgctgttc ggcaaatttt
     3901 gtcaaagcat caacagtgat caaatcgtcg tcttcatcgt ccatgtcgcg aagttcgatc
     3961 tctgtttctt cgatatccaa gacacgcatg tccagaccta gtgattgcaa ttctttcacc
     4021 aatacgcgga atgattccgg tacacctggt tttggaattg gttcaccctt gacgattgct
     4081 tcgtatgttt tcacacgtcc gactacgtca tctgatttgt atgtcaagat ttcttgtaaa
     4141 gtataagccg caccgtaagc ttccagtgcc catacttcca tttcaccaaa acgttgtcca
     4201 ccaaattgag ctttacctcc caatggttgt tgtgtaacca atgagtaagg tccgattgaa
     4261 cgtgcatgca atttgtcatc gaccatgtga gcaagtttga tcatgtacat cacaccgaca
     4321 gacacacgtc catcaaatgg ttcacctgta cgtccgtcgt acagaacagt tttcgcatcg
     4381 ctggccatac cggcttcacg aactgtttcc catacgtctt catcacttgc accatcaaat
     4441 actggcgttg ctacgtggat acctaactga cgtgcagcca tacccaagtg taattccaat
     4501 acttgcccga tgttcatacg tgaaggcacc cctaaaggat tcagcatgat atcgattggt
     4561 gttccatcag gtaggaatgg catatcttct tccggcataa tacgggatac aaccccttta
     4621 tttccgtgac gaccggccat tttatcccct tcatggattt tacgtttttg aacgatataa
     4681 acacgaacta acatgtttac gcctggtgac aattcatctc cagcttcacg agtaaagatt
     4741 ttcacatcgt gaacgatacc gccgccgcca tgtggtacac gtaatgatgt atcgcggact
     4801 tcacgagctt tttcgccaaa gatcgcatgc aatagacgtt cttctgcaga taattctgtt
     4861 accccttttg gcgtgacttt ccctacaagc aaatcgccat cttggacttc tgcaccaata
     4921 cggatgatac ccatttcgtc taaatctttt aatgcgtctt ccccgacatt agggatttcg
     4981 cgtgtgattt cttcaggtcc taattttgta tcgcgggctt ctgattcata ttcttcaata
     5041 tggatagaag tgtatacgtc atcttttacc aaacgacggc tcatgatgat cgcatcttca
     5101 tagttgtacc cttcccaagt catgaaacca actaaaacgt tttggcctag agccatttcg
     5161 ccttgttcca tagatggtcc gtctgccaga gtatcccctt tttcgacttt ctcacccaaa
     5221 tgaacgattg gacgttggtt gtagcttgtt ccggagtttg aacgacggaa ttttgttaca
     5281 tcgtatttat ctaatgcacc gttgtcgcgg cgtacgcgga tttcagaagc atcaacgtat
     5341 tcaacgacac catcatgttt acataacaaa gcagctcctg agtcatgcgc tgatttgtat
     5401 tccataccag taccaaccca tggtgcttga ggattgatca acggcactgc ttgacgctgc
     5461 atgttggcac ccatcaaggc acggttggag tcatcgtttt ccaagaaagg aatacatgct
     5521 gtcgcaacgg caactacttg tttaggtgat acgtccatgt agtctacttt atcaatagat
     5581 acttctaagt tttcactttg agcacgagcc ataacaacgt cttgagcaaa tgttccatct
     5641 tcattcaatg ggctgtttgc ttgggctacg atgtaatggt cttcgatatc agctgtcaag
     5701 tagtcgattt ggtcagtaac acgacctgtt tcacggtcta cacgacgata aggtgtttcg
     5761 ataaatccga atttatttac tttcgcataa ctggacaaac tattgatcaa cccgatgttt
     5821 gggccttcag gagtttcgat cggacacata cggccatagt gggagtagtg aacgtcacga
     5881 acttcataac cggcgcggtc acgagtcaat ccgccaggtc ctaaggcgaa aagacgacgt
     5941 ttgtgtgtca attcgccaag agggtttgtt tgatccatga actgtgacaa ctgagaagaa
     6001 ccaaagaatt ctttgatact tgccacaact ggacggatat tgatcaattg ttgaggtgtc
     6061 aatgtttcag tatcttggat cgacattctt tcacgaacca cacgttccat acgtgctagc
     6121 ccgatacgga attggttttg taaaagttca ccgactgaac ggatacgacg atttcctaag
     6181 tggtcgatat catcgacatt gccgatacct tccatcaagt tcaagaaata gctcattgaa
     6241 gcaatgatgt cggctggacg aaccgttttt acagctgctt ctggatagcc gtttccgatc
     6301 acgtttactt cacgttcagg gtctcttggt gaaaatactt tgatgacttg gacagtcatt
     6361 ggatctgtga ccacaccgtc ttctgatgga tagtaagtca ctgaatttag gccattatca
     6421 atgaaaggag ctagtgtttc catgacttgg tgagtcagaa ctgttccttt ttcaacgatg
     6481 atctcgcctg tttctggatc aactaatgtt tcagctaatg tcagattcaa tagacgtgtt
     6541 ttcaaatcta attttttgtt tactttgtaa cgaccaacgt ttgctaagtc gtaacgtttt
     6601 ggatcgaaga aacgagcatt cagcaagtta cgtgagctgt ctgctgtttt tggttcgcct
     6661 ggacgcaaac gttcgtaaac gtctttcaaa ccttcttctg ttcttgagtc gcttgcgttt
     6721 ttatgcaagt ctttttcgac tgtattgcgt aatgtttcgc tgtcgccgaa gatttcaaag
     6781 atcgtatcat cggaaccaaa tcctaacgca cgaactaata cggttaaagg aatcttacgt
     6841 gtacggtcga tacgtacata agagatgtct tttgcatcag tttccatttc tagccaagct
     6901 ccacggttag ggataacagt agaaccgaat ccttcttttc cgtttttgtc gacttttcca
     6961 tggaaataga cacctggtga acggactaac tgagaaacga ttactcgctc tgccccgttg
     7021 atgatgaatg ttccttgttc tgtcattaat gggaaatcac cgaagaatac ttcttgtgct
     7081 ttgatttcgc cagtctcgcg gtttgtcaaa cgcaatgtta catgtaatgg tgcagagtag
     7141 tttgcatcat gcgcacgagc ttctgctact gtatactttg gttctttcaa ttcataatct
     7201 acaaattcca aagatagatt gccattgaag tcatcgattg gcaaaatgtc ttcaaacatt
     7261 tctctaagtc cctcatctaa gaaccattgg taagagtctg tttgaatttc gatcaaattt
     7321 ggtaattcca acacttcact gattcttgcg aaacttctac gttcgcgatg ttttccgtat
     7381 tttactacgt gtccagccaa gctcttcacc cctctaaaat gtcattcaaa aagactaccc
     7441 gatcaattgt tacaataata tttcaaatat tatttttagg taacaacaga cattttttgc
     7501 ggcttttagg caaaaaaaaa ccaaaaatag aacattctct tgaaacctta cttcgtgagc
     7561 ttctactttt gtttccttat attaaagccg aaacggacaa tatttcgttt ctgccttttc
     7621 ttcatcagat agtttttgca acttcatata ctacacttat tttctataaa agtcaacact
     7681 tcctggcgtt tcttctgctt tttcgcaaca ttttcttaat gttttcaatt ttatgttttc
     7741 aattatctga caattcttaa ttgacagacc tttttatctc ggttatactt tagaaaattc
     7801 attttgtgga ggaacttcta tgcgaaccaa catcaaccaa atcgcaccaa cacaactgaa
     7861 taacttttac tttagctact ttagataggt ttgtattcat catgatggat acaaacgtta
     7921 aacgacagtt tgtatctatg atggctaaag aactttgtat tgcagcaaaa agccacgtag
     7981 acaaaatgct aagtggctga gcagtgaaaa tacaaagtaa aagtatcaag cattctactt
     8041 tttcaattta ttttccgact tttcaatcca tttggacatt ttgtctgaat ggattttttg
     8101 tttcccaaaa ttaaggagga aaaagaaatg aaaaaaaata taatcatcgg attaggcgct
     8161 gccctgctac tagctttagg aggttgcgca caaaaagaca attccgcaga ggcatcagat
     8221 ggacaaaaaa caattggcgt attgcaactt gtacaacata actcgttaga tgctgcctat
     8281 aaaggattca aagaaggatt agcagaagaa gggtataaag aaggcgataa tctaacaatc
     8341 gattatcaaa atgcccaaaa caatcaagac aacctgaaaa gtatgagtga gaaactcgtc
     8401 aaagaagatc ctgatttgct acttggaatc gccactccag cagcacaatc tttattaaat
     8461 gaaacaacca ctatcccgat gactgtcaca gcggtcacag acttggaaca agcccattta
     8521 gtcacatcca atgaaaaacc tggcggcaat gtgactggca cgacagatat ggtgccaatc
     8581 gaaaaacaaa tcggcttact gttaaatatc gtgccagacg ccaaaacaat cggcatcatg
     8641 tataacaacg gtgaagcaaa ctctaagatc caagctgatt tggcagaaaa agaattgaaa
     8701 aaagcgggcg tcaaagtcaa agtactgaca gcaaattcca caaatgatgt ccaacaagtg
     8761 acgaaaagtc tagctaaaga tgtagatgga atctatattc ctactgataa cacgttcgca
     8821 agtgcggcaa gtgttgtcgg tgaagtcgca aaagaaacaa aaacacctgt cgttgctggc
     8881 gcagttgatc aagtcaaaga cggcggtcta gcaacagtag gaatcgacta cgaaagcttg
     8941 ggcaaacaaa cagggatcat ggcagcaaaa atcttagacg gcaagaatcc aagtgaactt
     9001 cctgtcgaaa cagcgaatga tttggaactg tatgtcaata aagacatggc caaagcatta
     9061 ggcatcaatc cagacagcat caaagaagct gaataaaaca caggaggatt ctcatgacaa
     9121 atttgctctc tcttttctta tcatctgcat cgcaaggggt cttatgggcc ctacttgcga
     9181 ttggtgtata cgtcactttc cgtatcttgg acattgccga cttgactgct gaaggaagct
     9241 ttcctttagg tgcagggatc gcggcagtaa gtattacaaa tggctatcat ccattgacag
     9301 cttgtcttct aggcttttta gggagtgcgg cagcagggct tgtttccgga ctgcttcaca
     9361 caaaattgaa aattcccgcc cttcttgcag ggatcatcac catgactggt ttatattctg
     9421 tcacatcccg tgtgatgggt gcgccgaaca tctctttatt gggtcagcca acgatctttc
     9481 attgggtcga gtcattcggc ataacaaaag acaacgctgt actgatcgtc ggtctgcttt
     9541 ttgctttgat cgttgtatgt ttacttgttt tgttcttacg tacagaaaca ggacttgcta
     9601 ttcgtgcaac tggcgataat ctggcaatga gcgaagcaaa cgggatcaac acagataata
     9661 tgaagatcat cggttatatg atttctaatg gatgcattgc tctttctggc tccttgcttg
     9721 cgcaaaacaa cggctttgct gatttaaatt ctggtattgg aacgatcgta attggacttg
     9781 cttctattat catcgcagaa gttttgttac gtaaccagcc actatttctc cgtctcttga
     9841 ctgtcgtttt aggtgcggtc atttatcgtt ttattttagc gttagtcttc gaactgaatg
     9901 ttgaaccaag tgattcgaaa cttgcttctg ctttcgtgct agtgatctgt ctttctttcc
     9961 cgcagatcca gcaaaaattc catttacctc aaaaaaagaa aggcggtagt gtcaaatgaa
    10021 tgacgtctta acattggaaa atctccatca tacctttgaa aaaggaacga tcaacgaaaa
    10081 tcatgtcctg aaaggcatta atctttcctt agatcccggc gacttcgtga cgatcatcgg
    10141 tggaaatggg gctggtaaat ctactttgct gaacagcatc gccggtacat tttctgtcga
    10201 tcagggtcaa attttattga atggaaaaaa tatcacgaaa aaatctgttg tcgaacgttc
    10261 gaaatccatc agtcgcgtat tccaagatcc taaactaggg acagccgttc gtttaacggt
    10321 agaagaaaat cttgctcttg ctatgaaacg aggaaaaaaa cgcggcttct tccgtggtgt
    10381 caaaccacaa gaccgaacat ttttcaaaga ccagctggtt cggctaaatt tggggttgga
    10441 aaatcgttta tcctcagaaa tcggtttgct gtctggagga caacgtcaag ctattacgtt
    10501 attgatggcc acattacagc gtccagaact gatcttatta gatgaacaca ctgcagcgct
    10561 tgaccctgct acttccaaaa cggtgatgga attgacagaa aagctgatca ctgagcagaa
    10621 tctcactgct tttatggtca ctcatgacat ggaagacgcg atccgctatg ggagtcgact
    10681 gatcatgctg catcaaggaa ggatcgtcgt agatatccag caagaggaaa aacagcagct
    10741 cacagtgccc caattattag cgttgttcaa acaaaacagc ggcacggcat taaaagacga
    10801 tcaagtactt ttatcttcat aatcagaaag aggatgggac aaaaaatgaa cgcccaccct
    10861 cttctttttt ctctttcctt ctttcgtttt tgctttatgt atcaaccgtt gtttcttcga
    10921 aaactatttt gttctctcct tcttcctgat agaatggatg ggaaaggagc ttgatgccat
    10981 gacaacgaaa gacaaggtac ttcaattatt gaaaaagaca ccagattttc tttccggaga
    11041 aaagttggca cagcaactgg aagtttcccg gacaagtatt tggaaagcca tcaaagaatt
    11101 ggaaaaggca ggctatcgtt ttgagcacgg gcctacaggg tatcgttacc tgccctctga
    11161 cgtactagat gcaaaagaaa tccagcaaga gctacggtcg tttattcctg atttgaaagt
    11221 acaaacgatg atgacttctg aatctacgat gaaagatgcc aaactggcag cagctcaagg
    11281 agattctgtt tcgaagttat ttgttgctga tacacaagaa caagctcgtg gacgttttgg
    11341 acggcctttt ttcgctgaac ctggacgagg aatctacatg agtctcttgc tccatccaga
    11401 caaacggttt gatgaattgc ctcaatatac gatcatcgca gccagtgcct gtgtgaaagc
    11461 cattgaatct gtaaccggtc gttctgcttc gatcaaatgg gtcaatgata tctacatgga
    11521 tggaaaaaaa gtctgtggga ttttatctga agcagtcagt gatatggaaa gcggcaggat
    11581 cagtcatatc atcattggga tcgggcttaa tttttctgtt cctcaaaatc attttccagc
    11641 tgatctccaa gaaaaagcca tctctgtctt tcccgacgga caagctagtg tcacaaggaa
    11701 tcagctaatc agcaaaatct ggcaagaatt gttcacttat ctttctcacc cagaaaaagc
    11761 gttggacttc tataaagaaa aatcattcgt attgggaaaa accgtgtcgt tcaatcaaaa
    11821 aggaacgact tatgtcggtc ttgcaaaaga aatcggtgat catggcgaac tgatcgtcca
    11881 aacaaatgaa cagaagatga gtttgtcttc tggcgaaatc agtctcacat ctatccgtac
    11941 gcaataatta tcagatttca caaaaggaca cctgatctca tacagtgtcc ttttttctga
    12001 attctcttca aaagactctc cttattctat cagctgacag tttctctatc ctctagaaaa
    12061 aggtattcta aaaatatcta taaagcatgg tacactttct ttaaatgaat caatgcaaaa
    12121 aacaagagag tcatcagttt acacgatcaa aagagatagc aggccgcttc ctttttcaat
    12181 cttatagata gaccatgggt aacgataaaa acaaaaaaga acttgcgact tattttgccg
    12241 taagttcttt tttagctagt gccttaatct cttaatccca acaaacgtct cgcatagatc
    12301 acctgaccag agtgcatagc agcatcatca ataatagaaa cgagacgcat tcctcgtgtg
    12361 actggtggtg tccagttctc gtcaattact tcatctagct cggaaggttc cagccttctt
    12421 aagtaagaaa tagcaaaatc agcagctcct cgcaagtatc ctagcagatc ttctatttga
    12481 ttagcttgga tctgctttgc ttgttccaga ctatgcttcc aatcttgttc gttatctgct
    12541 atcgtcatcg gaaaccggct ttcccagtct tgactatgcc aaattggaga agttcctgct
    12601 aaatcagcaa tctggaaatc taattctcga gcggtatgcc aagccagcca agtcattgat
    12661 ttgatctgcg gggctctatc ttccactgga aaacgattgg cctcctcaat agagacgcct
    12721 tcaaacaaac gttcaaaccg atcgtatgcc cgatccacac tctcgcatag catatctaaa
    12781 taatccattt attttcctcc tttttattta tcctacttac tttttcctaa ttctaggata
    12841 cctacttata tgttactaca cacccttatt ttttacactt taacagtcac catcatcaat
    12901 agtttggaga ttgaaagaaa aagatagtgt cgaactatca attgaacaag aagcaacaat
    12961 atgaacgttt cattaatatt ctttaaataa acaatgattt ttcaaacgaa cagtttaaga
    13021 ctaggagaaa aagagtataa taggaaaatg tttgaaagga aaggaagggg aaaaatgaaa
    13081 aaaagggcaa gtttactagt cctagttgct ttgttgttca atatcttttc gtatggtgtg
    13141 gccgtttcag cggaaacata cattcctaaa gaccctggga atatttataa tgatctaact
    13201 ggtaactatg gcttgttagg aattgctagt caattccacg tatttgctaa aaataagaca
    13261 actgtgaatg cacatacaga cggaaatata gcaacacatg aacttgatgc aaaaaataat
    13321 tttggtacag agcttcatga aggtttattg aaccaagaaa taaattatat acaaaaaact
    13381 gattctttcg ctaattcttc aggcatacct acaggtagca caagaatgaa taaatttgtc
    13441 gttggcagta acgtggatgt agcacttcaa gatggtcatc ctacagtcaa tggatccagg
    13501 cttgatcact taactccaga tgatttttat aaagatcgtg ctgggcatga atatattgat
    13561 ttcgagcagg aatttgctaa attgaatgta gcagcaaatg atcttgcaac gatcactcca
    13621 gctaaaacat atactgctgc agattttcca gacatgaaca atcggacaat cgatttaact
    13681 gatttatcag ataccgggtt tttattggta aatatcgatg cagaagtgtt aacgatgaat
    13741 acgccacttc aaatcattaa tccaaatgat caagtagttg tatttaatgt catcaacagt
    13801 tcttctgcat tgaacgtaca gtcaccaatc aaatacaatg atcgttcaaa tcatgaaaca
    13861 gaagattttt cggatgcgaa tatctcttgg aattttggaa atgagatgac tgatttgaca
    13921 atcagtgctc cttttcaagg aacaatcctt gcgcctaatg ctactatccg cattactcaa
    13981 aaccaagacg gaacgattat aggaacaaat gtgattttag atgcagctac caatcgttgg
    14041 gatcctaacg aaatatttat cagcgacaat ggtacagata cgacagacac aagcgacagt
    14101 acagatacat ctaccacaag tgatagctca gattcatcaa cttcaagcga cagtacagat
    14161 actacctcta ccacaagtga tagcacggat acatcagctt caagcgacag tacagatact
    14221 acctctacca caagtgatag cacggacaca tcagcttcaa gtgacagtac agatactacc
    14281 tctaccacaa gtgacagcac ggacacgtca gcttcaagcg acagtacaga tactacctct
    14341 accacaagtg atagcacgga cacatcagct tcaagtgaca gtacagatac tacctctacc
    14401 acaagtgata gcacggacac gtcagcttca agtgacagta cagatactac ctctaccaca
    14461 agtgatagct cagattcatc taccactaca agtgatagca cggacacgtc agcttcaagt
    14521 gacagtacag atacatcctc taccacaagt gatagctcag attcatcaac ttcaagcgat
    14581 agtacagaca cgtcgtctac cacaagcgat acacgtcatg caagtgtctc cttctcaaaa
    14641 acaagttcgg ataacaggac gaactttaac ttaactaata aaacaagcaa tgacaatgga
    14701 aacaaatcaa aaagagcact tcctaaaact ggaagtcaat cgaataattg gataacactc
    14761 gcaggcgtta tattacttgt aatcggttta agaatcactt ttatgagtta taagaaatcg
    14821 aaaaggtaaa aaaatattca agataaaaaa gagcaacgtc gctaacggac gttgctcttt
    14881 atttttgctt tttatcataa atacaagaac tacaattcaa tttgtcaaaa aacacgtaga
    14941 tttccttctg agaaatttat ttacgtatcg aacctttccc tattcagtct ttgcgatcca
    15001 aaatcagttg ggtaagggaa aagagattct cttttgttcg aagagaggtg gcaggtaatt
    15061 tctttatttc cttcaaagcc ttttctgtgt aagaggccgc taacttccta gcttcttcca
    15121 cgcctcctgt atgttcaacg attttgcgta cggcgtcgac atcttcttct gtcattgccg
    15181 ctttcttctc taaataaggt agtagctttg gtttgttttt ttgcaaagag tagatcaacg
    15241 gtaaagaata gaccccttga cgcatgtctt ctagtacagg tttgccgatt tcctggctct
    15301 cttttgtata atctaaaata tcatcgataa tctgaaaggc catcccgata gaaagtccga
    15361 tatctcctgc tttttttgcg aagcgctcgc ttgttccact ttcaaaagcg ccaacagaac
    15421 aacttaattg gaacagttca gctgtcttac ctgaaatatt ttccaaatat tcttttacag
    15481 aaagttcata attatagcga tcatccatct gccctaattc gccattcaat actttttcca
    15541 tactgcgaga attcaattgg agacttttca aggaagtgga gtaatcagac aatagtttaa
    15601 aacagcagac aaataaatag tctcctgcat agacagaaac gacattacca aactgactac
    15661 ggatattagg ctgaccacgt cgcagatccg cttcatcaac gatatcatca tggatcagtg
    15721 tggccgtatg gagcatttcg atagaagctg ccaaagcgat ggctttgtct cgatcttgct
    15781 ctggtccaaa ttgtgagaac aatagctgat aggcaggacg caacagcttt ccgccggcat
    15841 ggatcgtttc tttgattgct tgttcgacag gtttgttttt caggcggaca gtttcttcca
    15901 tccgttttag tgtttctgtc aattctttac ttaaagcagg atagttttcc cacattggat
    15961 gtagcttcat aaaaaaactc cttgtgtgac gattattttt tggtaaacat tgggctccat
    16021 ttttgtttgg ttccctgctc ataatctttt tggaatcgtt gaagtgtctg cacatgtcgt
    16081 aaaagataat tcgctgcgat cccgattgca atccctgata aaatccctaa aactgaaagg
    16141 actggcaagt acaacatgac tgtccatgat tgtgcaatga aagaagccat caaaagctgt
    16201 ccgacattat gcatgaaacc gccggccgca ctaattccga tgatactgac acgttttggt
    16261 cctaattgct tgaccaataa cattccaaaa taactaagca aagcaccact catactataa
    16321 aggaatgtgg aaatcgttcc gcctagcaaa gtagtcagga atagtcgtag ccaaagtagt
    16381 aagaagctgt cttgtttttt catggtaaaa atggcaacga tcgtgattag attggctaag
    16441 cctagttttg caccaggcgc aaaagaaaaa ggataaggga tcatattttc caataaacca
    16501 atgatcactc cttgtgcaac aagtagcgaa atataaatca ttttttgtaa tttactcatg
    16561 gtgtgtaaag gtctaataaa tcagactgtc ttcgtcacct ccatctgttg aacggacttc
    16621 gatcactaat ttatgtggca aacagacgat ggtttcgcca tttttcgttg cccagcctcg
    16681 acgtacgcag atctggtcat cgcaatctgc ttcttttatc cgtactcgat cgccatctat
    16741 ctcgatcaag ttataatctc cgtgttcatc tttgtaagta tatgtgttgc tctcttctcc
    16801 agccatcaaa gggaatgttt tgatttctgt gccatccaca cgcagtaccg cttctttttc
    16861 tgctgttgcg gtgttttgct gaagaccaaa aatcatgact ggtaaaaaag aaagaacagt
    16921 caaaagcaaa ataataaaaa catcccaagg tttgagcaga cttttttcag caaattcttt
    16981 aaggctcatt tttgttctcc tttttccaga ttaactcacc caattttagc ataaaaacaa
    17041 gaggttgtga cacctgtgtc ttgctttgag taataagaac gaagaataga aaacagcttt
    17101 ccatgttttc taattctttg ggcttattac cgagaagcag caggtggaac accgtttata
    17161 acaagaggtt gtgacagaag tgggcaactt caagaaataa gaaggaattt acgaaaatta
    17221 cttttcaagt ttttgtgaaa tttcggctta tttttcgaag aagctacttc tggaacaccg
    17281 tttataacaa gaggttgtaa cagaggttgt gacacctgtg tcttgctcat ggaggcttat
    17341 ctcgggcatc ttattccttt aattttacat aaaaaggagg ctgtgacggt ttgtctcagc
    17401 ccctttctat tgaaatcttg cattcaaata acgttcttta tctatttatt tcttgccgta
    17461 ctgggaactt ggtctaccgt accaccaatt acctagtgta cgttgtagcc atggaattac
    17521 ccagcgatcc aacccaatcg cacgtccgga accgttcatc aatgcgaaag caacaaaaat
    17581 gaaccaaatg tttacccagt aaaacatgcc tgataagcag aacgtgatca ccaatacaat
    17641 cgttgtcgca ctgcatagcc atgtgaataa tccagcaatc aatgctaatg ccaaggcaat
    17701 ttcaaagaat accatgaatt tttggaagaa cattgctaca tcattgtttg gcatgatcac
    17761 ttgcatgatc tttgtgaacc agtctggtga cttctcaatc acagccattg gttcttcacc
    17821 gtatgcataa ctcaaaccaa aatgtgcagc ttgagtcgct gcttctccgg cacttgcccc
    17881 tgctccgctg gcagctgtgg ttgcatcacc agcagcagaa gcaccactgg caacatctgt
    17941 tacattgtat tcccatgtcc aagggaacac actgtttcca gtgaaccatg atccttcacc
    18001 aaaccaagta cttggtttga acacttcacc attcccaatg atttttttgg aagcttcaac
    18061 gaaccaaact aaaccataga aaatacgaag tggcacactc cataagacat tgccgtaacg
    18121 agaagaatgt cctcgagtca cgttgcgatc atctttgata tggaaaaact catgcattaa
    18181 atattggaac atataataac cagaacgaat atcaaagaag tatttcaaat tcacgatatg
    18241 tttcattacg atagctaaaa atccgcttaa atggatctta tcaaataggt tagctacccc
    18301 ccatttggca ccaatagaaa ccataaatcc ttgatagttt cctttaaatt tatgcttttc
    18361 tccgcctttg atcgaagcca cgatattcgc tgcggctgtg tgtcctgttt gttcagcagc
    18421 ttgaacgatc tgcggtgtcg gtgttcctgg gaattcttca taaaagacta aatcaccaat
    18481 gatatagatg tttttatctt cgtagccttt tgcctgcata tattcattgg cgatcaaccg
    18541 ctgtccgcgt gctgattcta atccaaagtc agcagcgtca gaagttcctt tgacaccagc
    18601 tgtccaaatc agtgtgtgag tcggaatgtt gcgtccgtct ttcaatttga tatgatcagc
    18661 agccacttct acgattggtg cattcaataa taattccacg ttgtgcttac gcaaatagcg
    18721 ttcagctttt gcagcatcat ttcgatccaa catattcaag atcgtcggca ttgcctctac
    18781 gaccatcagt gtgatttcgt ttggatctaa tttataatct ttggctaggc gatttttcca
    18841 gtcgatcagt tccccaatca tttcaatacc ggtaaatcca gaaccacaga caacgaaagt
    18901 cagcatggct ttacgcagtt catcatctgg ttccaatgca gcttttgcta ctgtcttctc
    18961 aatatgttcc cgaatcctta cagaatcttc aaatgaccaa agggtgaatc cgtgtgcttt
    19021 gacaccaggt gtaccaaagt cattcggctc tccgcccatt ccaaggatca gctgatcaaa
    19081 aggataggaa cctaatttgg tcttgacgat ttttcgttct ttatcgatac cgattacagt
    19141 gtctgtgaca agttgtacat tcttttgacg agcaaacaaa tgctgcagat cgtattggat
    19201 tgcttctggt tctacacgtc cgccagctac ttcatgcaac tcggtcatca tagtatggta
    19261 cgaatgacga tcgatcagag taattgctac atcttctttt ttcagtttct ttgccaagta
    19321 ttttgtagct gaaacaccgg catatcctgc tcctacaacg acaatatttt gctttgccat
    19381 tgatcatccg ctccttatag actatctata taatgaatat atgataattc ttttagtttg
    19441 atacttatta cacaatctcc atatattata tagatgttct gttcttttgt ctaactcctt
    19501 ttggattttt ttcaaatttt aaaataaagc gttttttcac gaaatttgct gaaagaaaac
    19561 gtttgaaata ttacatgggt tatttatcaa aaatagttga cttataggct aaaaagatta
    19621 gaatgtataa tgaatcacaa agaaaaattg tggactagaa atggaatggt ggggtattaa
    19681 aatgaagaaa aaacgttttg taactggatt tgccgtatta gcattttcag ctctagtgtt
    19741 aggcgcttgc ggcgcagatg acaacggaag ctcaaactct tcttctgaat catctacagc
    19801 acaatcttcg actgcaaaaa gcacaacaga atcatctgca aaagttgtag ctggcggaga
    19861 tttgcaagac ggcacatata aattagaaga aaaaaattat tcaaatggtt accgtgcagt
    19921 ctttgaaatg gttgtaaaag acggcaaaat cactgaatca aaatatgata acgtcaatga
    19981 aaacggcgaa tcaaaaacaa aagatgcaga atacaacaaa aacatggaag caaaatctgg
    20041 cacaaaccca gaaaaataca ttcctgagtt gaatgaccaa ttcttaaaag cacaaagcgc
    20101 aagcggtgtg gaagtcgtaa ctggagctac tcactcatct gaaagcttcc aaaactacgc
    20161 acaacaattg atccaagctg ctcaagctgg taacacagat acaatcgaaa tcgacaatgg
    20221 tgctgatttg aaagacggca cttacaagct tgaagaaaag aactactcta acggctaccg
    20281 tgtgcaattc gaaatgacag ttgctggcgg caaagtaact gaatcaaact ttgattatat
    20341 cgacaaagac ggtaaatcaa aacaagatga tacagaatat aatgaaaata tgaaagcaaa
    20401 aagcggtaca gaaccaaaaa cttacatccc tactctgaac gacgaattcg tcaaagcaat
    20461 gggcgaagaa gatggctcac ctgctaatgt agaagttgtt acaggtgcta cacacagctc
    20521 acattcattc atcatgtacg cacaacaatt agtgaatgca gctgaaaaag gcgacactca
    20581 aacaatcgaa gtagataata tcgtaacaga aaaataatca cataatcata ctaataaaag
    20641 ttggagggtg ggacgatagc cagattaggc agtcgtctca cctttcaaaa tgaagagagg
    20701 aaaaagatgc ggaaaaaact actattttcc ttaatcacac tgggcatctc ttttatggtg
    20761 ctaactggct gcagcaactc agcaaataaa acaaccactg aaagttcagc agctaccaag
    20821 atattgaaag atccatattc tgatgaacag ttcttgttag ggacttacgt tcgtatccgt
    20881 gtgtatgatg aaggcaaaga atcagcattg aaacctgcct tcgatcgagt aaaagaactt
    20941 ggtgataaaa tcacgatcaa tcaaaaaggt tctgagatcg atgaagtgaa tgagcaagct
    21001 gggatcaaac cagtaaaagt ttctgatgac gtctacacgt tagtcaagcg ggcctacgaa
    21061 tatagccaag attctcaagg cggattcgat atggcgattg gtgcaatcac acaattatgg
    21121 cgaatcggtt ttgatgacgc cagaaaacct tcccaagaag aaatcgatca ggcattgaaa
    21181 ttagtggatt atcataagat cgaactaaat gacaaagaaa aaactgttta tctaaaagaa
    21241 aaaggaatga tcatcgattt aggtgcaatc gccaaaggtt acattacgga cgaagtagtg
    21301 aaagtcttga aaaaacaagg agtgaccact gccatcgttg acttgggcgg taatgtctat
    21361 gtcttaggcc acagcccaag aggcgaaaac caagactgga cagtcggcat ccaagatccg
    21421 aacatggctc gcggatctgt tttaggttct attaaagaac ggaacaaaac attagttacc
    21481 tctggaattt acgagcgtta tttagaagta gatggcaaaa aataccatca tttgtttgat
    21541 ccaaaaacgg gttatccgtt cgacaatgat atcgcaagtg tcacgatcat aacagataaa
    21601 tcaattgatg gtgacgggtt gtctacagca gtcttttcaa tgggtgtgaa aaaaggactg
    21661 gaatacgtcg aaagcgaatt gaataacggg acggaagcga tcttcgtgac aaaagacgat
    21721 aaagtatatg tgaccgatcc aatcaaagac accttcaaat tatcggagga ctcccattac
    21781 acgatgggtg accgttctga actaaaataa ggagtacgaa ccatgacact aaaaatcttt
    21841 ttagaagtag ttgaaatacg aacaaaggtg gctagtgtat ttccttttgc ggtaggggta
    21901 ttattctcta tcgctttttt tcatgagata cattggctaa acactttttt attttttatt
    21961 ggaatgctag tttttgattt agcgactacc gctatcaata attacatgga ttatgaaaag
    22021 gctcattctg aagtatataa gtatgaagaa aatgtcattg gccgcagaaa tctatctcct
    22081 gtattgattc gaaacatgat tttagctatg attgcatttg tttttgttat cggcgttatt
    22141 ctaacgatca atacgggttg gcttttactt ttgatgggat ttatctgttg ttttattgga
    22201 gtattctata cattcggacc gattccttta tctcgaatgc ctttagggga aattttcagt
    22261 ggggtgacta tgggccttgg aatttttgcc atggtcgttt atgtcaatac attcggttca
    22321 gatgtctatg atctgacagt caacttttca tctggacaat ttgctttggt aggaaatctt
    22381 tgggctatag cagcaatcgt attagcttcc ttacccttgg tgtttacgat tgccaatatc
    22441 atgttggcta ataatttgcg ggatcttgac cgtgatattg aaaatcatcg ctatacacta
    22501 gttttttata tcggacgtcc tgcgggaaca gtcttattcc agctattgat gtatgcttgc
    22561 tatttcgtga ttttaatggg gttgttgagc ggtatctatg aatggccgat cttggtcacc
    22621 ttcttgacct tgccaattgt gaagaagcat ttggatcaat tcaagcaaac gttaccccag
    22681 cctatcagtt tcagctattc catcaaaaat atggtcttat tcaatgccag ttatgtattg
    22741 gggctattac taacaatcat tatgcaagcc atttaacagc atgaagaggt tgtgaaaaaa
    22801 ctgccctgca tcaagtaata agaacagcca aataaaaata gctccttata tttttcgttt
    22861 ggttgggctt attaccgcag atgcaagctt ttgaacaccg tttatcagga ggttgtgaaa
    22921 aagtcgctta gtttcgagta ttaagaaaaa ttttgtgaaa atggctttcc acatttttgc
    22981 ataaatttgg cttaataccg agaaactggc ttttgaacac cgtttatcag aggttgtaaa
    23041 atcagtgttt tgtcctgagt attagagaaa caaatggaaa aatagttcct catattttgc
    23101 cgttttttga gctaataccg aaggacagct gattgaacac tatttgttcg gaaaaagtga
    23161 ctaactatga cacaattttt ttcacagtcc cttttttcac ttgatttgat tcgtaccagc
    23221 gaacttgacg agaactttct tggtttggta actatatggt attcttttaa catcctcgtt
    23281 tgcttcttct aatttattta tacaaagtca cactttttta aacatctgtt cttcgataca
    23341 tttctatttc ttttaaacat cgataccaat attttgaact taagagtgca taccaaatgg
    23401 attcatttac tcttcgtcag ttacgaagat aatcaaaatc tccaacttcc ctacttattt
    23461 cgttttgaga attatcgaag caatcttaca taaataacta aaaaacaaaa aaccagaaaa
    23521 tcagtatact gattttctgg ttttacatgg tttgttcaat aaaaagctgt tggaactgtt
    23581 aatattaaat tatcgcatcg ttacgaattc ttccgctcct gttggatgga tggctactgt
    23641 attgtcaaag tcttctttag ttgcacccat cttgatagcc acggcaaaac cttgcagcat
    23701 ctcatcgaca ccaacaccaa tagcatgtaa gccgacgatt ctttcttctt ttccgacaca
    23761 gatcaatttc atttcgcatt tttggcgata atcatttaat gcaaagtaca ttggggtaaa
    23821 gcgtgaacga taaactttca attcattttc gccatatttt tccaatgctt cttcttctgt
    23881 caaaccaatt gttgcaattg gtggatgcgt aaagacgact gtcggaacaa gtttatagtc
    23941 aagataagaa tctttctttc cattaaataa acgttctgat aaacgtctac cagctgcgat
    24001 tgcaacagga gtcagatcta atttaccgat cacatcacca acagcaaaaa tatgttcatc
    24061 cgttgtattt tggtatttat ctactttgat aaaccctttt ttgtccaatt ccacatttgt
    24121 attttccaga cctaattttt cggtattcgg tacacgtcca ccggcaaaaa gtacacaatc
    24181 accagttaag gtttcaccat tttcaaatag caccgtatat tcgtcattgt ttttagtaat
    24241 ttctttagca atatgatgtg cgtaagtttt tattccagct tcttggtaca tttggatcaa
    24301 attgtccgaa agcattttat caaacgttct aagtggtcgt tcttttcgat atgcccacat
    24361 gacttcacta cctaaaccac gaaatacacc tgaaagttca gccgcaatgt atccagcacc
    24421 taaaacgatt gctctcttag gtaactctgt taattcaaaa aatccatttg aatcaattgc
    24481 gtattctcca ccaggaatgg tcattttact tgcacggcct ccagtagcga tcaagatttt
    24541 aggagcacga taggtttcac cgtttacttc gatcgtttga ctatcgataa aagtagcgta
    24601 accttttata gcctcgacat gattgctatc taatcctctt tgataagcac cgtgtagaaa
    24661 atcaatatat ttttctcgtc tttctactag accggcgaaa tcaacatttt ttaaatctgc
    24721 ttggataccg taacttgagg catctcgttc aattgtttcc aaaatcgtac ttgcttgcca
    24781 cataactttt ttaggtacac aaccgacgtt gacacatgtt ccgcccaatt cattcgcttc
    24841 aatcagcaaa acttttgcgc catgcatccc tgctctgttt gctgaagcaa taccgccaga
    24901 gccgccacca attacgatgt aatcatatat ttgcattttg ttcctcctta ttgaagagat
    24961 caatcaaaac ctttatttaa cgatcctttt tctacagaaa acaagtgtaa cacttttctt
    25021 gaattttgta tgcgaagatg cttaaaacag ggatatatca gctttttcct tatttacgtt
    25081 ttcggatcat atctccaggt ttcaccggct gtgcgactgg catagttaaa atcatcattg
    25141 gatttggtgc tcggtcaatg gattcgcctt cttcattatg cataacttca acggtttgac
    25201 tgaaatgact gaatcctgga ccataaaatt cgatttcatc tcctacagaa aacaagtttc
    25261 tctgacgtat cgtagcaatc tgtgttgcct catcataaga taatacttca ccgacaaatt
    25321 tatatactgg gattttacga cgttcaccga ataattgttc gttttcagtt ggtgtattgt
    25381 agtaaaaacc tgtagctaat tctcgttgtg ctactttcca taactcgtcg atccattctt
    25441 gcttgcagac atagttttca ggatcttcca tataactgtc tacagccgct ttatagacat
    25501 ttgacaccgt agatacataa tggatcgatt tcattcttcc ttcgatcttg aagctgtcta
    25561 cgccgttttc aatcaattct ggaatatgtt cgatcattga catatccact gcactcatcg
    25621 agaattcttc ttccacttcg cctgtatcag ttaaactgtt tcgttcttga ccaaaaggca
    25681 tatcgaacaa tccatacttc cagcgacaag attgagaaca tccgccacgg tttgcatccc
    25741 gcatcgacat atggttggac aatgtgcatc gaccagaata agagatacac atggcaccat
    25801 ggataaatgc ttcgatttcg gtatccgtat ttttacgaat ctctgccact tcctccattg
    25861 aaacttcacg agctaaaacg acacgttcca acccttcttc tttccagaat tccaatgtct
    25921 caaaattagt tgctgaagct tgagtggata aatggatcgg cagacctggg gcttctgtcg
    25981 cacaaatttc gatcaaagct ggatcagaaa caatcactgc agaaataccg acatcacgca
    26041 aactgcggaa aaattcccct gctccatctt catttccttc atgggtgacc atattagcag
    26101 caacgtatac cttcgcatca tgttcttttg caaaagcaac tccttcagcc atttcttcat
    26161 aagtaaaatt acctgcacgg cttcttaaac catatgcatt cccgccaata tatactgcat
    26221 ctgctccata atggatcgcg gtttttaact tttccagtgt tcctgctggc gctaggattt
    26281 ctggtcgttt caattttctt tttactgtca tttctttcat catactcctt atttgatagc
    26341 agaaggatca atataaaaga atcctgtatc taattcacgg ttttcaggat gcaatttact
    26401 gatttcgcta gtcatttttt ccgctttttc ttgatcccag ctaccttcta aaatttgttt
    26461 ttttgcttcg gcgaatagtc gagtgatgtt tacgaatttt tcgcctggag taaataatcc
    26521 gtccaatttc catgtacagt aatgatgctg ataaagttca ttcaattcat tcgagagatt
    26581 cagatcattg ctggcaaaaa tatgtgtgcc atgactatct tcataaatag aataatgtgt
    26641 ctcttctttt ttaggttccg agataaaaag acctctttca cgatcttttt gttcgtcttg
    26701 tttcgtatag ttatagtaat tctgtagcag tggacgtttg gattgatgga tgcatgtagc
    26761 accatacaca agggtttcta caggaatatc gagtttttct tccatcgcct tcatctcttc
    26821 aaaaggaact tcacgagcaa gtactgctcc aactgcgcct tttttcgccc agaaattgat
    26881 ttgacgtgcg ctcgttacta atgtttcagc atcataaata tacggtatac gcaattcagg
    26941 attttttttc atcgtataaa taatacctgt atcaccaact gtgatcacat ctacgtttat
    27001 ttcttttaaa aaagccaaat attcaggtac atttttcatt ttttcaggat gaatgatccc
    27061 atttacagca atattcgctt ttttaccata cttgtgtgct aattctacca attgtcgctg
    27121 ttcttctcgt gtaaatgaag caggcagacg caatccaaat tgctcttcac cgaaatatag
    27181 tgtatctgca cctgcagcaa gcaactgttc tgcttgttca atagtttcta ctgtggttat
    27241 gagttcgatc ataattttct cctcctacaa cttcataata gtagcatagc tctaaaaact
    27301 ttccaatact tcttctattt aaagtcggat ttttgaaaat tatttcacaa aaaatcaaaa
    27361 taaagttcga tatattctgt ccaaatataa aaagagattg tgacaaaaat cttgtcacaa
    27421 cctcttaatc aagtcttact attataaaaa ttcagctaca caggccaagt aactataggg
    27481 aacctactgt ttccttttta ggtccgcgaa cattcaatgt gatcttacct tttgaagcac
    27541 ctactgttac gtggtcacct aaacgaattt ctccgccaag caaagcctcg ctcaatcgat
    27601 cttcaatttc tttttgaagt gcgcgacgga ttggacgtgc accatattca ggatcaaatc
    27661 cagctttccc gatcacatcg attgcagatg gtgtgatttt cacttgaata tcttgttctt
    27721 tcaatcgttt gataatcgct ttgctcatga tttggacgat tgtatggatt tcatctttac
    27781 tcaatgaatg gaagacgaca gtctcatcga ttcgattcaa gaattcaggt cggaaagctt
    27841 tctttaactc ttctaagata cgtttttgca tggctttgtg atctttagta acatcttgga
    27901 cattgaatcc gacatttttt tcttctcgaa tttgtgtcgc tccgatattt gaagtcataa
    27961 tcatgattgt atttctaaag tccacttttc tacctttaga atctgttaaa tgaccatcat
    28021 ccaatacttg cagaagtaaa ttgaaaacgt ctggatgtgc tttctccact tcatctaaga
    28081 gaatcactga atatggtttt tgacgaattt tttctgtcaa ctgtccacct tcatcatacc
    28141 ctacgtatcc tggaggagac ccgattaatc ggcttgtact gtatttttcc ataaattctg
    28201 acatatcaac acggatcagg gcatcttcac ttccaaacat gacttctgaa agtgctttgg
    28261 ccaattctgt ttttccgaca ccagttggtc caaggaacat gaatgaacca attggacgat
    28321 caggatcttt caatccgctt cgtgcacggc ggatcgcacg tgaaactgct ttgacagcct
    28381 catcttgacc aacgacacgt tcatgcagaa gtccttccag ttctaacaag cgttcgcttt
    28441 cttttttctc caactgctgt agagggacac cagtccactc cgatacaact gtagcaacat
    28501 cttcttctgt tacacgatca gaataacctt gctcctgttt tgcttcaatt gcagaaactt
    28561 tttgcagctt tttacgtagt gctttttctt gtctgcgtaa ttgagcagca ttttcaaagt
    28621 cttgtttttg gatcgctgct tccttttctt gtactagttc atcgatttct agtttgatca
    28681 cagttgattt tgttaagtga tcggtttgat ccaaacggac tttcgctgct gattcatcga
    28741 tcaaatcaat tgctttatcg ggtagttgac gagaagtgat ataacgaaca gaaagattga
    28801 ctgctgctcg tacagcttca tctgtgatct ccactccatg gtgctcttca tatcttgtac
    28861 gtaatccttg aagaatcact tctgcttctt caggagttgg ctcatctact tgaatgcgag
    28921 caaaacgtcg ctctaatgca gaatcttttt cgatatattt ttgatattca tctagggtcg
    28981 ttgctccgat cgtttgtaat tctcctcgag ctaacgccgg tttcaagata ttcgaagcat
    29041 caattgctcc ttctgctcca cctgcaccaa ttaaggtatg caattcatca atgaataaga
    29101 ttacttgacc atcattatag atttcgtcga tgaccttttt cattcgatct tcaaattcac
    29161 cgcgatattt cgtaccagca accaaagatc ccatatcaag catcatcagg cgcttttctt
    29221 gcatgtcttc tggcacttca cctaaaatga ttttttgagc taacccttca gcaatggctg
    29281 ttttgcctac accaggttca cccaccagta cagggttatt ctttgtccgt cggctaagaa
    29341 tctggataag ccgtttcact tctctcgaac gaccaacaac tgggtccagc ttgttttctt
    29401 ttgctaattt cgtcaaatca cgtgctaatg aatctagcgt aggtgttcct tgcggtgttt
    29461 gccgtttatc ttgtacattt acatttctac gacgattcat tccttttcca gcagaatcac
    29521 cagctagccc cattttttgt ttcagaactt gacgggcttt tgaaaggctg atacctaagt
    29581 tgatcatgat tcgagtagcc atgatacttt catcttttaa taagctcatc aaaatatgtt
    29641 ctgttccaac tttttgagaa ccagttttct tcacttcgct gctagctaaa gcaaaaactt
    29701 gtttcattct tggtgaatat ggaagaaaga ctcctttagg gtaagaacgg ataccaccat
    29761 aaccaatcag atgttcaatt tcttcataaa tttccgtttc attcaaatcc atttcacgta
    29821 atacttttcc agcaattcca ttttgctcga ccactaaggc tagtaaaaca tgttctgaac
    29881 taactgattg atgtttcaac cgttttgctt cttcttgtgc aatttctaat actgcttggg
    29941 ctctttcagt aaaaagttct tccatctaat ctcacttccc atcttcataa cttaaacgtt
    30001 ccagaaatgc tcggagaatc cgagcacgtg tatgatcttc atattcattg aaattcaatg
    30061 tgttttttgc aattgcactc aacatcaagt ttccttcttt ttttgtaatt atttggtctt
    30121 cataaagttt ttgaataata gcaaaagcat ttttctcact gattgtatca tcaaataact
    30181 gatttatctg ctcaagtaat tgttttttat ctgaaatcct tacttttgca attcgtatat
    30241 aaccaccacc accacgtttg ctttctacta gataaccacg ttggatggta aaacgggtat
    30301 taatcacata gttgatttgt gaaggaacac agttaaagag gtctgccatt tcaatccttc
    30361 gaatctcgat catttcacta ttttccagaa ttttctttat atatgattca attaaatccg
    30421 aggtattctg atgtgccatc ttattcattc cctttgacta atattgacct taattataac
    30481 gaatttgata atagaaagaa agaagaacgc tttttgttaa ataaatcctt tagaatcaac
    30541 aaaaaaaaat acggaatata ctattccgta tcgacgcgcc caagaggagt cgaaccccta
    30601 accttttgat ccgtagtcaa acactctatc cagttgagct atgggcgcat attcaattta
    30661 aaaaaattat aaatcatttg aaaacaaaaa gcaagataaa aaaaatcggg aagacaggat
    30721 tcgaacctgc gaccccttgg tcccaaacca agtgctctac caagctgagc tacttcccgt
    30781 ttaaaaaata aaaaagac
//
LOCUS       DAZUJR010000029        30586 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.029, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000029 DAZUJR010000000
VERSION     DAZUJR010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30586
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.029"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..2052)
                     /gene="glyS"
                     /locus_tag="ACG804_001225"
     CDS             complement(<1..2052)
                     /gene="glyS"
                     /locus_tag="ACG804_001225"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HFS4832168.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEIIPFEILDVKTDRASRGHRFLGEDVTFTHAKEYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKNHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEA
                     MKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     AS"
     gene            complement(2054..2971)
                     /gene="glyQ"
                     /locus_tag="ACG804_001226"
     CDS             complement(2054..2971)
                     /gene="glyQ"
                     /locus_tag="ACG804_001226"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HFS4832169.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENMKEAE"
     gene            complement(3355..4167)
                     /gene="recO"
                     /locus_tag="ACG804_001227"
     CDS             complement(3355..4167)
                     /gene="recO"
                     /locus_tag="ACG804_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HFS4832170.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKSGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            complement(4310..5209)
                     /gene="era"
                     /locus_tag="ACG804_001228"
     CDS             complement(4310..5209)
                     /gene="era"
                     /locus_tag="ACG804_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HFS4832171.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(5224..5619)
                     /locus_tag="ACG804_001229"
     CDS             complement(5224..5619)
                     /locus_tag="ACG804_001229"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFS4832172.1"
                     /translation="MDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            complement(5603..6079)
                     /gene="ybeY"
                     /locus_tag="ACG804_001230"
     CDS             complement(5603..6079)
                     /gene="ybeY"
                     /locus_tag="ACG804_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HFS4832173.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(6096..8288)
                     /locus_tag="ACG804_001231"
     CDS             complement(6096..8288)
                     /locus_tag="ACG804_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing metalloprotein"
                     /protein_id="HFS4832174.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIVCGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNDKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            complement(8312..9283)
                     /locus_tag="ACG804_001232"
     CDS             complement(8312..9283)
                     /locus_tag="ACG804_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HFS4832175.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            9989..11368
                     /gene="brnQ"
                     /locus_tag="ACG804_001233"
     CDS             9989..11368
                     /gene="brnQ"
                     /locus_tag="ACG804_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFS4832176.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            complement(11524..11970)
                     /locus_tag="ACG804_001234"
     CDS             complement(11524..11970)
                     /locus_tag="ACG804_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HFS4832177.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(11997..12173)
                     /gene="rpsU"
                     /locus_tag="ACG804_001235"
     CDS             complement(11997..12173)
                     /gene="rpsU"
                     /locus_tag="ACG804_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HFS4832178.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            complement(12335..12763)
                     /locus_tag="ACG804_001236"
     CDS             complement(12335..12763)
                     /locus_tag="ACG804_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFS4832179.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            12855..13715
                     /locus_tag="ACG804_001237"
     CDS             12855..13715
                     /locus_tag="ACG804_001237"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, water dikinase regulatory protein"
                     /protein_id="HFS4832180.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPSVEFNLFRRT
                     FVTDEKTLMQALQDALEEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            complement(13799..14149)
                     /locus_tag="ACG804_001238"
     CDS             complement(13799..14149)
                     /locus_tag="ACG804_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HFS4832181.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKTKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAIIQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(14165..15892)
                     /locus_tag="ACG804_001239"
     CDS             complement(14165..15892)
                     /locus_tag="ACG804_001239"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HFS4832182.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     TIIQKMTEE"
     gene            complement(16105..17031)
                     /gene="trxB"
                     /locus_tag="ACG804_001240"
     CDS             complement(16105..17031)
                     /gene="trxB"
                     /locus_tag="ACG804_001240"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HFS4832183.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            complement(17176..18609)
                     /locus_tag="ACG804_001241"
     CDS             complement(17176..18609)
                     /locus_tag="ACG804_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFS4832184.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFPV
                     ITGKKKMFEFDENHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            complement(18609..20012)
                     /locus_tag="ACG804_001242"
     CDS             complement(18609..20012)
                     /locus_tag="ACG804_001242"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008706 - 6-phospho-beta-glucosidase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFS4832185.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPTMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMNELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            20242..21144
                     /locus_tag="ACG804_001243"
     CDS             20242..21144
                     /locus_tag="ACG804_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFS4832186.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            complement(21185..23071)
                     /locus_tag="ACG804_001244"
     CDS             complement(21185..23071)
                     /locus_tag="ACG804_001244"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFS4832187.1"
                     /translation="MGKYQELASKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGVVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTALLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPAFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNPGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEAGETDDRQKRSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSEAGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEEEGYSLETPVIVTNYTDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(23168..24019)
                     /gene="licT"
                     /locus_tag="ACG804_001245"
     CDS             complement(23168..24019)
                     /gene="licT"
                     /locus_tag="ACG804_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HFS4832188.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELYQVIQKKYKDTFGCVEKIADFLAEIFNYQMSTDEKMYLTIHIARL
                     VHENRCK"
     gene            complement(24477..26261)
                     /locus_tag="ACG804_001246"
     CDS             complement(24477..26261)
                     /locus_tag="ACG804_001246"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4832189.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPTITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLTKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            complement(26261..28012)
                     /locus_tag="ACG804_001247"
     CDS             complement(26261..28012)
                     /locus_tag="ACG804_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter transmembrane domain-containing
                     protein"
                     /protein_id="HFS4832190.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLAPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAALLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGCSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQKLEAKIEGGEA"
     gene            complement(28154..28378)
                     /locus_tag="ACG804_001248"
     CDS             complement(28154..28378)
                     /locus_tag="ACG804_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HFS4832191.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            28629..30215
                     /locus_tag="ACG804_001249"
     CDS             28629..30215
                     /locus_tag="ACG804_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HFS4832192.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFVVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADQIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETIEEIE"
BASE COUNT         8505 a         6587 c         5473 g        10021 t
ORIGIN      
        1 acttgctagt gacaaagcca tggcagcaat ttgacttaat tgcgttaatc ggttcttacg
       61 tactgctggt tcttctgcca tgaccatcgt ctgatcaaaa taattttcga tcagtgggcg
      121 aaggcttaca agctgatcat aattttcgtt gatcgtttgg tcagcaaagc ttgttttcat
      181 tgcctctact gctttgtgca gttctttctc cgcttcgttt tcgaacagtt cagggtctac
      241 ttctgattgt ttttcaagct ccgctttttt cgctaagttc acgacacgtg tcaaagcttc
      301 catcgatggt ttgaagtctt catctgcaag atgctgcttg aacaattgtg ctgctgcaaa
      361 tacttttgtc agatcttttt gttctgcatt caaaacagct tcgatgacat catgacggat
      421 attcttcgtt gtcaataatt ggcgcagacg gcctttgata aagtcgatca cctgttgttg
      481 tcccgctgac aagccaatgc caaaacgatc cgtatcttta ctgataactt cactaatcgt
      541 ttcttgcaga acagacaaag gaaaggccca ttttttcgat tcgatgattc gaacgacacc
      601 atatgcttga cggcgcaaag catatggatc gtttgagcca cttgggatca tcccaactgc
      661 aaagaaagaa aagatactat ctaatttatc agcaatcgct aaaacagaac ctactgtagt
      721 ctcaggtaaa tctccttcac tggatatagg catgtaatgt tcacggatcg ctgttgctac
      781 ggctggtttc tcgcctttca gcagagcata tttttctccc atgatccctt gtagttcagg
      841 gaattctcct accatgttgg ttactagatc aaatttatag atttcagcag cgcgttgcag
      901 atccatcaat tcttcctcag atagtcctac ttgttcgcct atgatgcgag cgatgacttg
      961 tacccgttgc attttctcat agatgctacc gattttttca tggaaagtaa cagtttttaa
     1021 tttttcaacg tattggtcga ttgaagcttt cttgtcttca ttataaaaga attccgcatc
     1081 ttctaaacga gccgtcaata ctttttgatt gcctcgtacc acattttcca attttacccg
     1141 atcgccatta cgagcagaaa taaaatgagg aagcaacata ccttgatcgt tccgtacttc
     1201 gaaataacgt tgatgttctt tcatagaagt gactagtact tcttcaggaa cagatagata
     1261 tttttcttcg aagtcgccag aaaagacagt tggatattcg actaaattgt tgacttcttc
     1321 tagtaaatct tcatctagat caatgatcca gtgatttttt tcggctaatt cgtttgcttg
     1381 tgtgatgatc atttcttttc ttttttgcgg tgaagcaata acaaattgtt cattcaattt
     1441 ttcttcgtat tcttttgcat gcgtaaatgt cacatcttcg cctaagaaac gatgacctct
     1501 tgaagctctg tctgttttga catccaagat ctcaaacggg attatttcgt catctaacaa
     1561 tgccacgatc cagtgaatag ggcgaatata ttcaaaatcg tattctgccc agtgcatcgt
     1621 tactgggaaa gtgaggcttt taatgacatc tgctaaacct gtcaatactt cttttgcttc
     1681 tttgccgtga gtgtatttcg ttacatagac atattccacg ccttttaatt ctctaaaagt
     1741 gatagcatct gtcgtcagac cttgtccgcg gacaaatcct tcagctgctt tcgtccagtt
     1801 tccatctgcg tccaaagcaa tttttttggc tggtcctttg acttcttctt cgctgtctgc
     1861 ttgacgttct ggaatgtttg ttactttgat tgctaagcgg cgcggtgtag aaaacgtttc
     1921 gatcgtatca taagtcaatt ggttttcatc taaaaatttt gctgtttttt cttctaattg
     1981 tttcatgctt ggtgtgacaa catgagcagg catttcttcc agcccgattt caagtaataa
     2041 gtcttttgcc atcttattca gcctccttca tgttttctgg atttgctgtg tttttattca
     2101 ataaagggaa tcctaatttt tcgcgttctg ccacaaagat tttggctaca gcacgagcca
     2161 tgttgcggat acgggaaaga taacctgctc gttctgttac ggatactgca ccgcgagcat
     2221 ctaataaatt gaatgtatgg ctgcatttca aaatataatc atacgctgga tgaacaagat
     2281 tttcatcgat acagcgttta gcttcttttt caaaacggtc aaagttgctt agtagcaagt
     2341 cttggtcact tacttcaaaa gaatatttgg aatgttcata ttctggttgt ttgaagatct
     2401 cgccatattt cacaccatca gcccattcca gatcatagac actttcaact tcttgaatat
     2461 atgaagcaag acgttctagt ccataagtga tctcagaagt aactggttta caaggtagtc
     2521 ctccgacttg ctggaagtac gtgaattgtg tgatctccat cccatcaagc catacttccc
     2581 aacccacacc ggcacacccc atcgatgggt tctcccagtt gtcttcaaca aaacgaatat
     2641 cgtgttctaa tggatcaatt cctaaaagac gcaagctttc taaataaagc tcttggatat
     2701 tttcaggtga aggtttcatt acgacttgaa attgatgatg ctgatacaaa cggtttgggt
     2761 tttctccata acgcccgtca gctggtcggc gggatggctc tacataagca gcattccatg
     2821 gttccggtcc gattgcccgt aagaatgtat atgggctcat cgtacctgct cctttttctg
     2881 tgtcataagc ttgcatcagc atgcagccgt ttgatgacca aaatttttgt aatgttaaaa
     2941 tcatatcttg gacggtcaat tttttactca tctgttttgc ccctttcaat ttttaagcgt
     3001 tgctgtcaat aagaatacag gaaagaaaac gacaaaaagt ccctatgtct gattacagac
     3061 atagggacga ataatttcgc ggttccaccc tacttccgaa taaagattcg gcagcttcat
     3121 ttatcgtact cgcaagtgcc tcttcaaaaa tcgtttgggt ccggcttcca ctctcccgaa
     3181 ctcgctaaac cacgtgtttt ttactgatct tggtcaatgt acgtattcat tttgcagttt
     3241 tcttgtttat ataatagatc ctctcagtga acgatctatt taatctacgg ttaataatag
     3301 acggaagtcc ctgtatttgt caaatagttt tgattttttt gttgtatctt tcatttattc
     3361 ttctttttca ggtatctctt tttcaggcat atttttctct ggcgtcttta atacgtgtgc
     3421 ccaagacttc atttgatcaa tgaacttttt gctttttaga tgaataccga catattcatc
     3481 atacaactgg tcaatgaggt cacggattgc ctgcttcgtt tcttctttca agtggattcc
     3541 actgatctta tcataagaaa tagccgaaaa cattcgaacg aaataaacag cgcgaggatc
     3601 tgcatgataa cggtgttcgt ccattggcca gtgtttctcg catatcacac cgccagattt
     3661 ggaagaatag tcaaattttc cttttgtttc cccgcatacg acacagtgcg tccaaattgg
     3721 cgcgattccg aagcgttgca gtatttgaac ttcaaagata ttcgtgatga tttctgcatc
     3781 atctccttga tccatccgct gcagagcttg ttgcgtaaat tggaataaat gcgggtcata
     3841 ttgatgatct tcgattgctg catctactag atttagcaaa taggtaccat aaccgctcaa
     3901 aaagatatct tcttggatgt tccgaaacgc atggacgtct ttgacactgc ttaaaaacga
     3961 caaaccttca cttcgaaaat taccgatata gactgcttcg gtaaagggga gcaaagccgg
     4021 agctaatggc tgattttgcc gatggattcc tttgatataa aacatcattt tgccagaaga
     4081 ttccgtaaag attttgacta atttatcttt ttctttgtaa ttacggctag ataaaatcaa
     4141 gcctttcgat tctgcaagct ggctcatatt ctccctccta aaaaataaat ctggaaaagc
     4201 agattctgcc gatccagatt atttatgttt cgatcttccg ccgtttttct caacgtgcgg
     4261 atttttatcc agtttatttc tatacttaac ctataagaag ttcagaatat cagtattcgt
     4321 cttttcggta gccaaagtct tgcagataga cttttttgtc tcgccagtct ttttggactt
     4381 tgacccaaag ttctagaaat actttgtctc ctaaaagatt ttcgatatcc tttcttgctt
     4441 tcgttcctac ttgcttcagc atttttccgc ctttgccgat aatgattcct ttttggctat
     4501 ctctttcgac gatgatcgtg gcctggatat ggattttatc attctcgttt cgcttcatcg
     4561 aatcaacaac gactgcgaca gaatgaggca cttcgtctcg tgttaaaaac aagactttct
     4621 cacggatcaa ttcagaaacg ataaagtatt caggatgatc agtcacttga tcatctggaa
     4681 aatattgtgg gccctctggc atttcactga ctaatacatc cattaagcgt tcgacattgt
     4741 ttccttctgt agcagagatc ggaatcactt gtgcaaaagg catctgcgtc gaataatctt
     4801 cgatgattcc cagcaactcg tctggatgga tcttatcgat tttattgata atcagataaa
     4861 ctggagaatg cacgtttttt agacgttcaa taataaaatc gtctccccgg ccgcgttttt
     4921 gatcagcact gatcataaat aagactgcat ccacttcttt caacgcactg taagctgctt
     4981 ctaccataaa atctcctaga cgatgctttg gtttatggat tcctggtgta tcgataaaaa
     5041 tcagctgagc ttctggtgta gtatatactc cttggatttt atttctagtt gtctgtgcct
     5101 tgtcactcat aatggcaatt ttttgaccca cgattcggtt caataatgtg gattttccta
     5161 cattcgggcg gccgacgatt gcgacaaacc ctgatttatg ttctggcata tacgttctcc
     5221 tttttaatta aacaacaaat gatatatttt agggacaaat aaaatcaacc caatgatgac
     5281 agcaaaacaa gcggtcacta aaactgctcc agctgccata tctttgattt ttttcccaat
     5341 cggatgaaaa tgaaaatccg taaacatgtc cactacattt tcaaaaacag tattgatgat
     5401 ctctactatc caaacgagaa aaacagctaa aagcagccat aaccactcta tccgatcaag
     5461 ctggaaaatc acgcccataa ataaagcaag gataccgaac gcaacatgtt tcctcatatt
     5521 gcgttcttcc tcaaaaacgg ttttgactcc ttggacagca aattccacag acatcaggaa
     5581 atgtttgttt ttctctacgt ttttatcttt tgagtccata ggcatccaag atctctttct
     5641 gtaaaccaaa catttctttc tcatcttctg gtgtcatatg gtcatacccg ttgatatgca
     5701 agaatccatg taccgctaaa aagccaagtt cccgatcata tgaatggccg taagcttctg
     5761 cttgttcagc agcacgttca atagaaatca tgatgtctcc tagtacacga ggcaaaggat
     5821 tctctccatc ttcaaaaatc actgggattt cgtcttcgcc ttcttcttcc agagcaaaac
     5881 tgatgacgtc tgtcggtgca tcttttccac ggtaatcacg attgattact tggattgccg
     5941 cattgtccat gaaagtaaca gacatttctg tttcctctgg cagctttaaa taagatgctg
     6001 caaattgcag caagtcatcg atttctttca ttttctcttc tgagacttgg tttgtttcat
     6061 ccataaaggt aatatccatt atacatcgct tctttctatt cttcttgttc ttcctttatc
     6121 ttctcaactt ctgttttcat tttaggatat ttgatccgag aatggaaggt gctacttaaa
     6181 ccgctgatca atgatttttc cacttttcgg atttctttca aggtcagtcc actatcgtct
     6241 aattgaccat cggaaatacg ctcttcgata agattatgga caaaactttc gattttttcg
     6301 ctcgtcggat gatccattgc ccgtactgca gcctcacaac tgtcagcaat attgacgatc
     6361 cctgcttcac gactttgcgg ttttggtcca ggataacgga attgctcttc tgttacttcc
     6421 ggattgcgtt ctttcgcttt gatgtagaaa taacgcatta gcgtggttcc atgatgctgt
     6481 ttgcaaatat cgatcaccat ttgcggcata ttataatctt ccaatatttt ggctccatct
     6541 gtcacatgtc caaagataat atgtttactg tcttctggca ataagaaatt gtgcgggttt
     6601 tccgctcctg aaggcaagtt ctcaacgaaa aagctagcat gtttgatctt gccgatatca
     6661 tgataatagc aagctactcg agttagcaaa gaacgtccgc cgatttctgc tacagcgtta
     6721 gcacttagat tagctaccat catactatga tgataagtac ctggcgcttc ttccagcaac
     6781 tgtttcaata aaggatgatt tggattgctg agttcattta atacaattac actgtcatca
     6841 ttgaccatca attcaatata tgggtgtaga ccgatcgtca gcaagaatga gaagagtgca
     6901 ccagtgaacc cgcagacaag cattaaccaa gtcgttgcat caccaaagct cattccttga
     6961 tagacgatca aaatgacatc catcatcaca ggaaaaataa tgacccacat ggcagcagat
     7021 aatccttgtt ctgagatccg tttgcgtctg acaatcgttg ccatgagccc agagaaaaca
     7081 taagacatca agataatcgt tagaaagttc gtgccaatcg aatcataaaa aatgaaaagt
     7141 gcagatactg cttggaaaat accagccatg atccctgctc ttcggttcaa gaaaaagctt
     7201 aaaacaagtg gtgcaaaagc agcgggataa aacagcggga tataagtagc ttgttccgtt
     7261 tggaataatt ggaaaaattt catcagcact atgctgactg acatagctgt cacatagaaa
     7321 agcacgtatt ttgttctttc tcctgcattt tggaattgaa gtgaattata aatcagtacg
     7381 ccgatttgaa gcaaaacagc taaaaccatg gcaatgagtg ggaaaatcga agtcgtttga
     7441 ttcgtcaatc ctagtaattc caattttttc atcgctgaag catcaatttg atttccttcg
     7501 cgaacaatga tttctccttg gaagatcatc actggttgta cagcttctcg tgcagattgt
     7561 tttaattctt ctgtcttttt ctcattcaat acatcattga ctacaatgcc ttgatccact
     7621 aagtagcgaa tcatttgttg ctgctctgtt gtgacattca aatactgaat ctgatcttct
     7681 gcttcttgtt taaaagcttc caattcgctt tcacgaactt gtttactcat ctgttcgtca
     7741 atgagcttca aactttcatc cctaaccgtg tgaatttccg tttcagtcat ttcaaatatc
     7801 gtcgaataaa aattgttcgg cagtttttgg taaaacgcaa cgttttctgc attcacgttt
     7861 tcaaaatttt tcttcagtgt agcaatccgc tcttctgtag taggtttcgg gatattttca
     7921 tcttccttcg ccttatctac cttgtcatta taagatttgt tgatggtatc attcgtctta
     7981 tcgatcaatt cgaataattg cttgatccga ttgttctggt catctgccag atctttttga
     8041 taagtatatt ctggagtcac tgcttctgct gccagttttc ttctttgttc ggtttcttcc
     8101 gtgttctcga tcgttttatt cgcacggata ctctcttctg ctacttggcc ttctctgaaa
     8161 tcattggcct tttgtttgac actactaaat gtaacgccgc agacaatgat aaaaaacaag
     8221 aacagaagga aaggcaatgc tgcctttccg agtttttctt gtagtttctg cagtgtttta
     8281 ttcaacatgt gcttatcctc ctaagcaaag cttattcttg atgaagatcc gccttttcat
     8341 aagctttgat gatttcggca actacagggt gccgaacaac gtcacttgct tcaaaattaa
     8401 caaaatcgat ttttttgatt tgctttagtg ttcgttctgc atgaacaaga ccacttgtcg
     8461 tccctcgagg caagtctatc tgacttgtat ccccattgac aatcattttt gattgataac
     8521 cgagacgggt caagaacatt ttcatctgag cgactgtcgt gttttgtgct tcgtccaaga
     8581 taacgaatgc atcatccaat gtccgccccc gcatgtaagc taatggtgcg atttcgatta
     8641 cgcctcgttc catcaatcgg ttcgtatgat ccaatccaaa aatttggtat aaagcatcat
     8701 aaacaggccg cagataagga tccacttttt ctttcagatc cccgggtaga aagcctaggt
     8761 tttcccctgc ctctacagcg ggccgcgtca aaatgatttt ttgcacttcg ccttttttta
     8821 gggcagcaat tgctaatact acggcaagaa acgttttccc tgttccggct ggccctacac
     8881 caaatacgat gtcatgtttg gctaccgatt caacgtattt cttttgaccg ctgtttttta
     8941 cccgtatagg ttttccatta cggtctttga cgatctcttc ctcatacatc tcaacaaaat
     9001 aatctaatgt acctttttgc cccattttca atgccgtcac gacatctggt gtacttacgt
     9061 ggattcctcg tttgatcaat tcctgtaatg tccgaatgac tgaggcagcc aaggaaatct
     9121 gggattgttc accaatgatc tgaatgattt ctccacgtgt atggatggtt gtttccgttg
     9181 tttcctcgat cagttttata tgcttgtcgt gtgcacctaa aagcatgctg acatcatcag
     9241 cagctgtcaa tctaatctct aaagaactag actcttccgt caaaaataga catccccttt
     9301 ttttcgattc attctttcct attttaccat actcagaaga aactatatag caaataagaa
     9361 aaggttgtaa aagagtcgtt taaccatacg taccaagaaa cgttaaaaaa tagctgtttc
     9421 cattcgctaa aggtctcgtt ttgataaaaa gaatctgaga atgtaagtta tatgaaagtg
     9481 gagaacaaaa tattccgttt cattcagagg tattctctag gtatttttct tgtttcaaaa
     9541 aaagaaaaca aaatagttaa aatattcttg catttcaaaa aaaacaggtg tattattacg
     9601 tcaacaaata aacatacagc aaagcgtcga ggaaaacagt aggctattca acgatttatt
     9661 cccagtgagt catgtaagtg agaaatgaca ataaatcgaa tagacgaaca tcatttccga
     9721 gtcaatgtcg aaaacgtaga tcattgtggc tgcctccatt atcaggctag cggataactt
     9781 tatcaaaaag cgtccgtgaa tgaagaagct tttttaagcg aaaaaaggtg gtaccgttct
     9841 agaatctaga gcccttttcc caagtggaaa agggcttttt tttatatttt aaggtggtgg
     9901 ttttcatgga atctgatatt agtggcatta ctaattgctg caacgtttat atcgtcaatc
     9961 aaaatgataa ttattggagg aaaaatttat ggaagaaaca aaaacttatt catggaaaca
    10021 actattgatg gtcagttcac ttatcttcgg gatgtttttc gggtcaggta atctaatctt
    10081 tcctgtccac ttaggtcaaa tggctggcgc aaactgggtc agtgctggcg taggatttgc
    10141 catctcaggc gctcttttcc cattactagc tatcttagct gtagtagtga caaaaagtga
    10201 tggtctgtat gacttagcta aacctgtcgg aaaatggtat gctgccttgt tcttaatcct
    10261 tgttcatttg acgatcggac catttttcgg tacaccacgg acagctgcta ctgcttttga
    10321 aatggctgct aaaccatttt tgcctgaaaa atataattca ttaggtatgt ttttattctc
    10381 tgctcttttc tttttacttg cttatttcct tactgtccat cccacacggt tggtcaaata
    10441 cgtcggaaag tatctaaact ccttgtttct tgcattatta gcaatcattt ttgtcgtttc
    10501 tttattccac ccaatgggaa atctaaatca atctgctgca gatacttacc aaacaaacgc
    10561 tttaacaaat ggtgtcctag aaggttataa cacggttgat gcagtagcct tgcttgcctt
    10621 aagtgtcact tttgtccatg cagtccgtga ccttggtttc aaagataaaa aagtcacaga
    10681 attaacagca aaagctggta gcctgagcgt tgcgctagaa gtcatgatct attttggtct
    10741 tgttcttctc ggtgcgatga gtttgaataa gatgtcttta tcagaaaatg gcggaactgc
    10801 actttctcag atcactaatt tttatttagg taacttcggc gctagcttct taggagtgat
    10861 ggtcacatta ggtgtcttca ctaccgctat gggactcgtt gtttcttttg cacaagattt
    10921 ccataaactg ttccctaaag tcagttatat gacatggctg cggttaacga ctttcgtctc
    10981 ttttgtcgtt gcaaatgctg gtttggacaa tatcatccaa tggtctttac cagtattgat
    11041 gcttttgtat ccattgtcgc ttgcgttgat tttgctttcc ttaacagcaa aatttttcca
    11101 aaagacacca tttgtctatc aagtaacgat gttgtttgct gctgttcccg ccgtattgga
    11161 tatgctggca aattcgcctg ctttagtgag tcaacaaaga gttgtagcaa gcatgctcga
    11221 attttatcat catcacgttc cttttgctgc attgggactt ggctggatgg tcccaacgtt
    11281 acttgggtat gctggcagct tactcttcta ttacgcctat cgcctatcag ggtataaaca
    11341 agaagcaaat gaactaccag aagaataacc agatcaaaca caatttaaca taagaaatat
    11401 taaacaggaa aaaaacagct agatgaaaga atcctattct ttcgtctagc tattttttag
    11461 atctcttttt tacgagcaca aaaaaactgc ggacaatgat tgtccgcagt ttaaatgata
    11521 aaattaagat tgtaatagtt ctttcacaat ggcatttact tggtttccat ctgcttttcc
    11581 tttgacttta ggcatgatcg cacccatgac tttgccaaat tctttcattg atgaagcacc
    11641 agtttgcgtg attgcttctt gaacaagttg tcgaatttct tcgtcggaaa gttgttccgg
    11701 catgtatttt tcgactatca caatttcact ttttactttt tcagctaaat cgtcacgtcc
    11761 tgcttcttca aactcatgca aagaatcacg tcgctgtttc atttcgcgag acaacaccgt
    11821 taattcttct tcttctgtca agtcgtgacc ttctttaatc tgctcgtttt gtatagatga
    11881 cttgatcatt cggatgactt gtaaagattc cttatctttc gctttcatcg ctgttttcat
    11941 gtcatcgttt aatctactta gtagtgacac actaccaact ccaattcatc acagaactag
    12001 aattttttgc gttttctagc tgcttcagat tttttcttgc gtcttacact tggtttttcg
    12061 tagaattcac gtttacgaga ttcttgtaaa gtacccgctt ttgacacgga acgtttgaag
    12121 cgacgaagag catcgtcaag tgattcgttt ttgcgaacga ctgtttttga catgttaatt
    12181 ccctccctcc gagcttaaaa agtaaccgta attgttattg aaatatatct caaaaaacaa
    12241 gactgtcctg taaatattat atctaatgct gttttgaccg tcaaggaaat cttgcttttt
    12301 tttaaaatta tcaaatgtta ttttatttaa atccttattg acaattttca catcttccga
    12361 aaatctcgaa tctatgccct tcgatcgtac atccaccgag ctgttcttcg aaataattca
    12421 ttggacacat atggatttct ttcgttgttc cgcacaccgt acagataaag tgatggtgat
    12481 ggccgatttc cccttgacag caatgaaaac gaaacttcat ctctccattt aaatcggttt
    12541 cttccagtaa atcgatttct gcaaaatcat ggagatttcg ataaatcgta tcgtaactta
    12601 ctcctttgaa ttcctgattc atatagtcaa aaacttcttt agcggatacg tagcgattgc
    12661 gcttcactaa ataagttaac aatgcttctc tttttttagt atatttaaaa ccgttatttt
    12721 tcaatgtttc tagtgattgt tcgatcaacg tctgtttttt catgacttat tcctccaaat
    12781 caaaatgatt acgaagtaca cattctagag tatggtataa taaacataaa aaaaatgcaa
    12841 gtgaggtttt atccatgtct tccgattcta cagaaatcgt tacttttttt gtcatctccg
    12901 actctgctgg agaaactgcg acaaaactag cgcaagccac tatggcccaa tatcctagcg
    12961 ttgagttcaa tttattccgc agaacatttg tgacagatga gaaaacattg atgcaggcac
    13021 tgcaagatgc actagaagaa aaagctcttg tcctgcacac attgatcaat caagaattga
    13081 tcgagatgac gcgttctttt tgtgaagaac atcaattatt tagttttgat gtgatgactc
    13141 cgccgatatc agaaatcgag cgcttaactg gtatcaagcc cattcggcaa cctggcgccc
    13201 ttcatttatt gaatgagaac tatttcaaac ggatcaaagc aatggaattt gctgtaaaat
    13261 acgatgacgg gaaagatcct cgtgggtttc tagaagcaga tgtcgttttg ctaggcgtat
    13321 cccgaacttc caaaacgcct ttgagcttgt ttttagctaa caaaaattta aaagttgcca
    13381 atctaccttt gatcccacaa gcacatattc ccaaacagct ttgggagatc gatcctaaaa
    13441 aaatcgtggg actgacgaat aacccagata ttttaaacaa tatccgtaaa gaacggatgc
    13501 gctcttacgg attaaatcct gatactgctt attccgatat cgaaaaaata cgagctgaac
    13561 tcgattttgc gaatgatctt tatgaaaaat tgggctgcgt agtaatcaat gtcgcttctt
    13621 tatctattga agaaacagct tcgcttattt tgaatgcttt agacctagaa gaccatagtt
    13681 attatggaac tgaaaccacc gaagaaacag actaacaatt tttctttaaa aaaactggac
    13741 tgtgtcagcg aagaagattc gttgacacag tccagtttgt ctctatttgc acctatcgtt
    13801 attgatgttc cacatgtttg agtgtctggt tcaaaatatc cagtacgtga gaatcatcaa
    13861 gactatacaa aatcgctttt ccctcacgat gggacttgac gacatggttt tctcttaata
    13921 aacgcagttg atgcgataca gcagattgtt ccatttccac tgcttggatg attgctgtca
    13981 cattttgttc cccgtctttc agatacagca gaattttgag acgagtgggg tcactcaaca
    14041 ttttgaatag ttggctgact ttctctactt ttgttttttg cgtgtctggc aatccattca
    14101 cctccaactt gaaaaaagac tgacttctaa agtttaccac tttttccatc agtctcaagt
    14161 ttttttattc ttctgtcatc ttttggataa tcgtttcata agcggctact ttttcagctg
    14221 cgtcttctga agagtttcct tttacaccga tataaaattt gattttcggc tcagttcctg
    14281 aaggacggat agcgatccag ccattttctt ccagcgtata cttcaatacg tcagatggcg
    14341 gtgtcgttag tttttctacg tttccttcac ggtctgttct cgtcaactct ttgaagtctt
    14401 ctgtttggat gacttttgct ccggcaaatt ctgttggtgc ttcttcacgg aatttttcca
    14461 tcaaagcaga gattttcgca gaaccttctt gtccgctcat tgtcacagaa atcgtttttt
    14521 ctgcgtagta gccataggtt tcaaaaatcg tttgcaagcc atcatacaac gttttgcctt
    14581 gttttttata gtaagctgct acttctgcta ataagagcaa tgcttggatc gcgtctttgt
    14641 cgcgaacgaa aggtttaact aaataaccgt aactttcttc gaatccgaac ataaaagtat
    14701 gggaatgatc ttcttcaaat tgttgaattt tttcagcaat gaatttgaat cctgtcaata
    14761 cattgaacat ggtagcccca tagtgttccg caattgctgt aggtaattcg ctagaaacga
    14821 tcgatttcaa taccgctgcg ttttcaggta aagtgcctcg cgattggtgt gcttccaaaa
    14881 tatattgagc aaacagtgct ccgatttggt ttccggtcaa tacttcatag gagccatttg
    14941 gcaaacgaac ggctgcacct aaacggtctg catcaggatc tgttgcaatc agcaaatcag
    15001 cgccttcttt ctcgccaagt cgtatcgcat actcaaaagc agagtgttct tctggatttg
    15061 gtgatttgac tgtagtgaaa tctgggtctg cgacagcttg ttctggaact agtacgaatt
    15121 gttcgaatcc agcttgtttc aacgcacgtt cgcccaacat ttttcctgtt ccgtgaagtg
    15181 gtgtgtacac aagtttcaaa tctttcccca ttgtttccac caattcatga tcaatcgtta
    15241 ctgctttgat ttcttctaga taagcggcat ccacttcttc tccgatgatc gtgatcaatc
    15301 cgctatgttc agcttcttcg tcagataata cttcaacttt taacggattg ctgacttcac
    15361 ggacatattt cgtcaatgca tctgcgtctg caggaggcat ttgtccccca tcttctccgt
    15421 agactttata tccgttgtaa gctgctggat tgtgggatgc ggttaccatg attcccgcaa
    15481 acgtcttcaa atgacggact gcaaaagaaa gctctggtgt tggacgtaga ctttcgaata
    15541 cataagatgg gatattgtga tgtgctaatg ttttggctgc ttccatggca aattctggtg
    15601 attgatggcg tgagtcataa gcgatagcga cacctcggcg ttttgtttct tcgccttgtg
    15661 tatccatgaa acgtgcaagt ccttctgttg cttgtcttac cgtatagatg ttcattcgat
    15721 tgatcccagg ccctaagatt ccccgcatgc ctgcagtacc gaattccaac ggtgcataaa
    15781 aagcatcttc aagtttttca ggatcttcac ccagatcatt taattgtttt tttaagtttt
    15841 cttctaaatt ttcttcatgt acccattgtt catacacttg ttcccaagac atgaaaataa
    15901 cacctctttc tgaaatatgg ttcttaataa gtatagcatt cacttattag atatgaaagt
    15961 atgaggacca aaaaacgctt aaatcaagaa aggattcttt tatcaagcac ggttgcaagt
    16021 attcgcataa atcggattca gtagatttca cgcgaaaaaa aagagtaaaa gaacaattaa
    16081 accgttcttc cactcttttt aaacttatgc agttgtttct tctaaagatt ccaagtattt
    16141 atacacttgt tgtccagcga tcccaccatc accaacagca gtagtgattt gtcgcaaatc
    16201 tttttcacga acatctccga tggcaaaaac gcctggtata ttcgtcttca tttcgttgtc
    16261 tgttggaatc cagccagctt cgttcgtcaa ccctgcttct ctaaatggtg cagttaatgg
    16321 atccagtcca acatagatga atactccgtc tgctgccaaa tcaaactcat tgccggtttt
    16381 gacattacgt gctttcacac ctgtcactac catttcattc ccaacgattt cgtcaacgac
    16441 tgtatcccac ataaaggaaa ttttttcatt cgcaaatgca cggtcttgga tgatcttttg
    16501 tgcacgtaat tcatctctac ggtggacgat gactacttca gaagcaaatt gtgtcaaata
    16561 gatggcttct tctactgctg agtctcctcc tccgatcact actagacgtt tgttacggaa
    16621 aaacgcacca tcacaaactg cacagtaaga aacgccacgt ccagcaaatt cttcctcgcc
    16681 aggtacgcct aatttacggt ggatacagcc tgttgcgata atgactgttt ttccttcgta
    16741 agttttatct tcacaaataa cttctttgtg gctgccgtga tccttgatat cttgcacgat
    16801 tccataagca ttttctgtcc caaatcttga aacaccttca tacatcttat aagctagatc
    16861 aggacccatt attgaatcga aaccaggata gttttcgatt tctgccgtat tgttcatttg
    16921 gccgccaggg gcgccttgtt cgatcatcaa tacggataag tttgaacgtg aagcatataa
    16981 agcagcagtc atcccagcag gacctgcgcc aataacgatt acatcataca tatgtagatt
    17041 ctcctttact taatcaagta agcatacttt acagccaatg cgaaaaaaag tctattgttc
    17101 tgcttgcgtt tctcgaatag ctttattata ctcgaaaaat ccgctgaaaa acaatagact
    17161 tttataaatc attgatcaat cattcgaaag attttctcca tttgaatcaa ttactttttt
    17221 ataccagttg aatgatttct tcttcgaacg ggctaatgtg ccatttcctt cgttgtcacg
    17281 atcgacataa atgaatccgt accttttctt catctcacct gtaccagctg atactaaatc
    17341 aatacatccc caagtcgtat agcctaatag atcgactcca tctaattcta ctgcatcttt
    17401 cattgcctgg atatgtgctg ccagatagtc gattcgatag tcatcttcca cataaccatt
    17461 ctcatcgggc gtatcgactg cacctaagcc gttttctaca ataaatagtg gtttttgata
    17521 acgatcataa atatcattca tcgttattct caagcctaat ggatcaattt gccaacccca
    17581 ttcacttgct tccagatatg gatttttgac agaagcaaag atatttcctg cagtctgttc
    17641 caagagttcg ttgtcagtag tcgaaactcg agaagaataa taagaaaagg agataaaatc
    17701 aacagtatgt tctttcagca atgcggcatc cccaggttcc attttgatct gaatgccatt
    17761 tcgttccatt tctttcaatg cataagcagg atattctcct cgtgactgga catcaatgaa
    17821 gaaataattt tctcgatctg attttctaga agcccaaaca tcttcaggat tgcaagtgta
    17881 tggataatat gctcctgctg ccagcataca gcctactttg ttctccggat ctacttcatg
    17941 agcaatcttc gttgcgatgg cacttgcaac caactcatga tgtgccgctt gatatttgat
    18001 ttgttcttca ttttctcctt cttcaaaata cagccctgcg cccatgaatg gtgcatgaag
    18061 gatcatattg atctcattga atgtcaacca atatttgaca agtcctttat agcgattgaa
    18121 gatgactcgg cacagatttt cataaaaacc aacgagttct ctggaacgcc acgcaccata
    18181 ttctttgatc aaatgcatcg gacaatcaaa atgtgtaatc gtcacaagcg gctcgatccc
    18241 gtacttttga cattctttaa agacatcctc ataaaatttc aaaccagatt catttggctc
    18301 tttttcatcg cccattggaa aaatacgact ccaagcaatg gacatccgat aagtcttgaa
    18361 ccccatttct gcaaataaag caatatcttc cttataatga tgatacatat cgatcgcaat
    18421 ttttgctgga taaaaatgat tttcatcaaa ttcaaacatt ttcttttttc cagtaatgac
    18481 aggaaaacgg tcttctccga ttggcacaac atctacgttc gctaacccac gtccgccttc
    18541 atcataaccg ccctcgcatt gattggctgc tgtagctccg ccccataaaa aatcttttct
    18601 gaatcccatc atacttcctc cattacatgt gtattgcttg ataattctct tgccagttca
    18661 tcttggactt cgattccttc tgcttttaac cggctgattg tttccttgaa ttgcggtaaa
    18721 tactgctgat gtgcaataaa caactcattc atgatccgtt ttgctgtctt tcctgatcgt
    18781 ataagcggat tgatcgtaaa cgcttgtaaa gctgttccat aatcaccagt cacagctgct
    18841 tcgatcgtca gcaattccat attcttcatt acttgcaacc agcctctttc agcagcagga
    18901 agggaaccaa acgctacatt tcgtgcgcct tgtgcgccaa cataggcagt gacttctact
    18961 acacaatctg ccggcagatc aggaacagct ccatcattct ttgtagatac cacgatctgt
    19021 gtttctttat ttccatagat cgaagcaatc gtttcacagg cagcatctga ataataagca
    19081 ccacctcgtt tttgcaattg ttcaggttta tgatccaatt ctggatcttt gtataattca
    19141 aacagctctg cttctgtttc tttcacttgc tgcgctcttg taccaatcgt ttgatattct
    19201 tctaaagcat gttccagcat ttcttcttca cggtagtaat agcggtggta gccacaaggg
    19261 atcatgttca tttgttttaa ttgttctttg aaaaacggga tatcaaagat atttttcggc
    19321 aatccattgt cttcatcgta taaacgatca atcaattctg ccgtgcggtc atttccttta
    19381 ttatctgcta ctttgtgcca atggaagtga tttagaccgg caaacttgta gatcagctct
    19441 tcttttttct tgccaagcat tgttggttct gtcatcatcg ccattactgg cacattgcat
    19501 aatcctatca ctttatccca tttgccatat ctgataactg cttctgtcac catcccgctt
    19561 gggttcgcga aattgatcag ccaagcattt ggacataaac gcttcatgtc ttcaacgatt
    19621 gccaaaacca ctggaacggt acgaaaagct ttgaatatcc cgccagcacc atttgtttct
    19681 tgcccaatca tcccataata actagggatc cgctcgtctt tgattcgtgc atctaattga
    19741 ccgacacgaa actgagtcgt aacaaaatcc gcatctttca atgcttcttc ccgatccaga
    19801 gttgcataga ttttgacttc atacggagaa gcatcccaca tacgctgaga catctgactg
    19861 acgatctcaa gcttttcttt tccttcttct acatctacga gccagatttc tcgtatcggt
    19921 aattcctcat atcttttgat aaatccttcc atcaactcgg gggtgtaact gctgcctcca
    19981 ccaatcgtag cgattttgat tccttttgcc atgttctcac tcctttactt tttacacttt
    20041 tattatcttt tttgtaaaca aaacaaacaa tagaaattcg tttctttcca gtaacattta
    20101 caaaagttag tgttttctac tggatttttg taaatatctt gtcaaaaaat gtctttatta
    20161 agctatataa cataaatccg tttacaaatc attttcaaaa aagttataat ttacgtaaaa
    20221 aaacaagaag aaggtatcta catgttatta cgtgaaaaaa tcaaagaaat ctccttttct
    20281 ccttcagaaa atgaagtgat tcagtttctc ttaagcgatt ctccagcact tggcgaaatg
    20341 accatccaag agattgctga gcgatgttat gtccacccgt ccacactcat ccgtgtagca
    20401 aaaaaaatgg gttttgatgg ctgggtcagt tttcgtaatg cttttttagc tgaaacagcc
    20461 tatcttgaag ggaattttca agacgtagat gcgaatcttc ctttttccac cacagacggt
    20521 attatgacga tcgcaaataa aatggcttct ttagaacaga tgacgattca agatacactt
    20581 tctctcattc atcatgacca actgcaaaaa gccaaacaac taatgcttca agcaaaaaaa
    20641 atcgtgattt tcgccagtaa ctcgaatact ttgatttctc aagatttcat gctgaaaatg
    20701 aagcgcatca aaatggatgt cacgattgtc accacttttg gtgaatcgtt ctatgaagcg
    20761 tacaattgca cgagtgatat gtgcgggatt ctgatttctt atacgggtga aaacaatgtg
    20821 atccttcgta ccgcagaaat attgaaacaa aatcatgttc caattttagc tttgaccagt
    20881 atcggtgatt caacgctatc ttcaatgagt acagccgctt tgcgacttac gacacgcgaa
    20941 cgactgtatt cgaaaattgg taattttacg atcaatacat cgatttgtta tcttctagac
    21001 gtgttatata gttgtgtttt tgcagaaaat tatcaacaga atttagtcca tctaatttct
    21061 gtaggacaaa aatttgataa acgccctatc agctcagcca tcatgaaaga gcctttcaat
    21121 tttgaaaata aagaagtgga ctaaaaagaa taattaagcc tagtccattc tttcacctaa
    21181 ccgttcaggt cagtgcggtg ataagtgcat cgtctggccc gaccgtctcc ccttgatttt
    21241 ccaaaatatc caaataatcc gtgtaattgg tgacgatcac aggtgtttct aaactgtatc
    21301 cttcctcttc gattttcttt ttgtcgaagc ggagcaacag atcgccttgt ttcactcttt
    21361 ctccttgctg caccaagctt tcaaaatatt tcccttccaa ctgaacagta tccaatccga
    21421 catgaatcag caattccaga cctgcttcag aaaccattcc gattgcatgt ttcgtcggga
    21481 acagggtcat gactgttccg tcaaaagggg cacgtacttc tcctttttca gggtagatca
    21541 agattcctcg acctagtgtt ccttgtgcaa aagctgcatc ctttgctgca ttcagtggag
    21601 cgatttgtcc ttgtatcggt gtttttacaa tttctttacc tgatcttttc tgtctatcat
    21661 ctgtttcacc tgcttcctcc ttccaaaaga aaaaagtcag cgcaaaggat accaccatcg
    21721 caatggcgat tccaatcaat acattaatca catccgttaa atcaccatct ggtctaatat
    21781 agttgggaat tgtaaagatg cctaatccac ctggattcca agaagttaaa ttcattaatc
    21841 cactatacgc gccccctaac gcaccaccga cacaggtaaa aataaatatt tttttacgtg
    21901 gcaatgtaaa cccataaata gctggctctg taatccccac aataccagaa acaatggctg
    21961 gtattgcgat tgctttgtct tttgggtttc taagcttaaa gtagagtgca gtaagtgctg
    22021 cagtttgtcc aaaagacact actgcaacag gtgtcatgat attttgccaa ccattcacag
    22081 aaaattgcat caatcccatt ggtacgattg cccaatggag accaaacatc actagaattt
    22141 gccagaagaa gcctacgatt gctccataaa taactggcga aagtgctaaa agtgtttcaa
    22201 atccagccat taaaatatca gttgcgaatg tgaatgctgg tccaacgagt aaaaaaccta
    22261 agggcattgt aataagaacg gtgaagaatg gaacgaagaa attcgcgatc atctcaggta
    22321 ctaacttttt aattggtttc tgaatttggc tagctaacaa cacaataaag ataatgggaa
    22381 tgacagaaga agcgtagtta cgcgcaatcc agggaatgcc gaatactgtt tgataaatag
    22441 gtgcttcaaa aatagtgcca gaaaatatgg tagtcagtgg tgcttctgct gcaccactca
    22501 aagcttccag cgacaagcta ggattcatta atgctgcccc aagcaacatc cctacgaatt
    22561 catttacttt aaatttacgg gcagctgtta aaccgataat aacaggcata aattggaata
    22621 cagaatcacc gatattatca aacataacaa atgtgccaga accgcggtca aatgcgccta
    22681 agaagacaag taatgctgtc agtccacgaa tcatcccacc agcagctaga atagcaagga
    22741 atggctggaa acagcccgat attccatcaa taagcatatc aaacggtctc attttttctg
    22801 ttgaaacagc ctcatcaaaa gtaaggtttc ctgcttttat aacctcttca aacacgactg
    22861 gcacatgatt cccgatgaca acttggtact gtcctcccgc tcgcattacc gtcacaacac
    22921 cgtccatatt tttcaagatc tcatcatttg ctttttcttc gttttttaat ttgaaacgaa
    22981 gccttgtgat acaatgtgtc aaaccattga tattttcctt cccgccgaca ttttctacaa
    23041 ttttgctcgc taattcttga tattttccca tttctattcc ctccaattta ttagtggaag
    23101 gtttagccaa ctgaatgtca ctacccttat ttcatgcgtt cttgttaatt tatcctcctt
    23161 tttttattta tttacaacga ttctcatgca ctaaacgcgc aatatggatc gttaaataca
    23221 ttttttcgtc cgtggacatc tggtagttga atatctcggc taaaaagtct gctattttct
    23281 caacgcaacc aaacgtatcc ttatattttt tttgaataac ctggtacaat tcctcagaaa
    23341 cttctcccac ttctgatttt tctccatcta ggacgcgtgt cagaaaaaaa cgtaggtgtg
    23401 tgacgaatcg aaaaaaatgg actgaatctt catcaaatgt aatcttatag taatagcgga
    23461 cgatatttag aatatcctgt attgttgtag taaacaggta ggtattgtct tgttggcttt
    23521 gaatgccttg tgcattgact aaatgcaatg cgataaatcc ggcttcatct tctgataact
    23581 tgatgtggta tttatccgag attttcttca ctgttttttt cccgatggca tactctttag
    23641 gaaatagttg tttgatatca tacagcaata catttggtac aaatattccc attttgtgac
    23701 gttcgatagc cgtatacaaa tgatccgtca atgcaatata caccgaatca ttcaactgga
    23761 cttgtagagc ctcttttgta tattcaatga tttcacaaga aatttctaag tactcaagag
    23821 gaatcgcttg tgccaattct tggaactgtt gtgaaagtcc gtcatttgtc aactgaaatt
    23881 ttttgtcgat gcatgagtca aaaatcgggt cacccacttt ctttttgaat gccaaacctt
    23941 ttcccatcac gatcatttcc tgatttcttt catccctggt tattacgacg ttgttattca
    24001 gtactttctc aatcagcatg ttttactcct ttccatgata tatagggctg tatccaaaac
    24061 aaaaagaaaa acccaaaaag ccgtccatgg aaccatggga gactcatcag gtttagcttg
    24121 catcaggcaa tcactatcca agttgtatcg ttttctttat attatcgaaa gcaagcactt
    24181 ttgtcaacgc tttcttagcg gctattgggc acttctgact agctgtcgtg atttttttta
    24241 aatctggtaa ttacgacact aacgctcaca gatgaagaat ctgggaagct ctgttttatt
    24301 ttcactctag cgcttaggtc aaaatgctac tatgctactg tcccaacttc taatatacgg
    24361 tgttccagta ccagcttatc ggtgataagc caaatttatg caaaaatctg gaaagccttt
    24421 tttacaattt ttttcttatc acctaaagct gaacggagcc ctgtcacaac cactttttac
    24481 acaccactgc tttgcagttt gtacatatct gcatacaaac cattttgcgc tagaagtgtt
    24541 tcatgattcc cacgttctac tatatgacct ttgtctaaaa ctaaaatcaa ttctgcatcc
    24601 cgaatcgtgg acagccgatg ggcaatcgca atcgttgtcc gtccttgtcg catttttgtc
    24661 aatccttctt ggatcaatcc ttctgtttca gtatcgatat ttgctgtcgc ttcatccaat
    24721 actagtattt taggatctgt cacgattgtt cgcgcaaaag tgatcagctg tcgttgtccg
    24781 ctagaatagc tggcaccgtg ttcgatcact tttgagtgat atccttttgg taattcatcg
    24841 atgaacttgt ttgcttgaac aaactcagct gcatggcgaa tctgttcgtc tgtgatagtt
    24901 ggattcatca tccggatatt tcctgcgata tctccataaa acaagaaggc atcttgcaag
    24961 accaatccca ttttcttacg taactcttcc attggatatt ctcgaatgtc atgatcatca
    25021 atcaagatct ggccttcata aaattcgtaa aaccgcatca atacgttgat gatcgagctt
    25081 tttccgcttc cggtgtgccc cactaatgca acggtctctc ccggattagc gacaaaagag
    25141 atattgttca atacattgtg ctctccatca taagaaaagc ttacattgcg aaactcgatc
    25201 ttacctgaag taatcgcttg atctgctcca ggattttgtt gcggtgcata ttcttctgta
    25261 tccatgattt tcaaaatacg actaccggca accattccat ctgtaaaggt gctcaaaaag
    25321 tccatcattt gagacattgg attaaaaaat ccctggacat aggtcgtaaa tgcatagatc
    25381 agtccaactt ctacgggaga atgcagcgca tcgatcccaa acaaagtcaa cgccaacgca
    25441 atcgccaatg catatagaaa attgatgatc ggacttaaca gaatcgaatt tgttttgatc
    25501 atcgcatagc gcgtgtctaa atactcgttg ttcacttgtt caaattcttt agctaaacga
    25561 gcttcttggc gaaactgctg gataatacgc atgccggaaa tcgattcatt caatttcgtg
    25621 ttcagctgac ttaatttttc ccgcatattc cggtaaatac gagaactgaa tttctggtaa
    25681 taccagatga cgattcctaa aatcggcaag aacaccaaag tccacaaggc aatttctcca
    25741 ttgatttgaa acatggcaat gaaggaagaa acgactgcaa agatcccagt caataccatc
    25801 aaaaagacat accaaaattc aaatagcgtt tctgtgtcat ttgtcactcg agaaacagtc
    25861 gatcctgccg gtgtctgatc aaaataacgc atacctagtg tatgcagctt ttcaaataat
    25921 cttacccgaa catactgata ggtcttcaat gaagccatgg aatacaaata ccattggaaa
    25981 aaccaaatga tacttttgac tatgactcca aacaagtaca taccagcaaa aaacaaaata
    26041 acttgtgtcg tagccgactg tttagccaga tgatcatcca taaaagtttg gatgatcctt
    26101 ggcaatagga cattgatcac agacagggca aacgcaaata agatagcaac gatgaacgtt
    26161 cttctaaaag gtttggcgaa cttcatcagt cgtttgatga tcttcttctg ttctttaagt
    26221 ggaatcgatt ttgtccattc cgattgataa ttttcatcca tcaggcctcg cctccttcta
    26281 tcttcgcttc taatttctgt ttctcccaca ttcgttcata ccagccgcct aatgcaagca
    26341 gctcatgatg ggttcctcgt tcaatgattt tcccttgatc gacaacaatg atttcttttg
    26401 catgcatcac gctgcttaaa cggtgagctg caatgatggt tgttttctct tttcttattt
    26461 cttttaaatt atgcaagata gcttcttctg ttttggcatc tactgcagaa agtgcatcat
    26521 ctaagatcag caattcagga tttttgatca atgctcgagc aatcgaaatc ctttgtttct
    26581 gtccgccaga taaagagact ccacgttctc caactaaggt atcataacct tttggtaatt
    26641 ccttgatttc attgttgata aatgctaaag aagccgcatg ctctacttct tcttctgaaa
    26701 gttttggatt agaaaaacgg atattatctc gaatggtcat cgaaaacaag aagtgatctt
    26761 gaggcacata gccgattgat cctaataaag cattcaatga atattctttg atcgaacatc
    26821 cgccaaattg aatttttcct tgataatcat cgtattcacg catcagtaat ttgatgattg
    26881 tcgtttttcc cgcaccagtt ttcccaacaa tacctaatgt ttctccttct tggatcgcaa
    26941 atttgatttg ttctaatgct ggtgattctt ctttcggata gttaaaagag gaaatagcta
    27001 cattcagctc gccttttgcc ggagtctgca ctgcacccag ttgttccacg atatgcgtct
    27061 tttcatgcaa aagttcattg acgcgatcat aagaagcatt tcctctttcc aatacgttga
    27121 acaatcgacc aatcgcaaac atcggccaaa caagcatacc gatatagcta ataaatgaga
    27181 ccatctgccc gattgagatc gtgccttcca agacatactt tccacctaaa ataattgttg
    27241 caacataaga cagaccgata atcaaggtaa tgaatggatc aaataaggag tctaaaaaat
    27301 tgactcgttt gtttttaata attgcatctt caatcttttc ttcaaaatcc gcgagatctt
    27361 ctttttcttg tccaaatgtt ttaatgactt tgatcccagt aatactttct tgtgtcttat
    27421 cattgatact agaaaaagct tcttgcgaat cacgaaaagc atcgtggagt tttgacccca
    27481 gcactcgtga agtaacggct agtaaaggca gaggaatcag cgcaatcagt gttaagcgcc
    27541 aatcaataaa caaaatcatc gcaatgatcg ttgttccgcc cgtgatcact gaatctgcaa
    27601 aggtcaagat accagctcct gctacatttt ggattgcatt caaatcattc gttgcatgag
    27661 ccatcaaatc tccagtccga tatttttggt aaaagagatt gtccatttct gtaaaatgtt
    27721 tgaatagctg ctgccgaagt tctttctcca accgagctgc acttccccaa atattcgtcc
    27781 gccagatata acgaaaaaga tattgtaaga gagctgcaag gatcaataat aagatccacc
    27841 aggaaatgat ctttattgat aaatttttat cggcgatctc atcaatgatg atcccaatca
    27901 cttttggagg agctaactgt accaaggcca ctgcgaatag ggagaaaatc ccaattaaat
    27961 aatgtttctt ttcctgtcga aaaaaccaac ctaattttct aaaaatcgac attttactcc
    28021 tcctttgtct ttatcaagag cataggattg tctgtgcttg tcttttttgc tgaatagtct
    28081 gaatagtcta acaaattacg aaataaaaaa cggactgaaa aaatcagccc gcaaaaagtc
    28141 tttgggtcag aacctatttt ttcccttggt tcttcatttg ctgcatcatc tggcgaattt
    28201 tcttctcaga tggtttttgc cccattgaca tcatcattga tcgcaacatg tcctcattaa
    28261 cgggaggatt tttttctaaa tagtctttca tatatttacg cgctaggaaa aagccaccta
    28321 ctgcgccgat tagcaaagca ataatagcaa taagtacgac aatacctgtt gataccatat
    28381 aaatctctcc tttctatttc cgaattgctc tcaatgattt attttactaa agtttattga
    28441 aaaaagaaag gcgtattctt tagtttcatg caaaaaatag tggttttttt agagaagaac
    28501 aaaatttctt tcattaacca gcaagacacg ccacgaaaaa aaattaggca taccaaatct
    28561 ttttctttaa ttttttcttt ctgaggtgta gaatgtaatc gtagataaat aggaaaggtg
    28621 gttttttctt gaataatcaa tccaacaaac aatttcataa gcatcgactt attgaacata
    28681 caaatggttt atctttagct gaagtaaatg gaacagtgga tgtacccaag ggaaaaagtt
    28741 tttttaaaac acttcttgct tactctggac caggtgcatt agtagcagtt ggttatatgg
    28801 atccaggtaa ctggtccact tcgatcactg gtggacaaaa tttccaatat ttattgatgt
    28861 cagttatttt gatgtctagt ctgattgcta tgcttttaca atatatggca gcaaaattag
    28921 gaatcgtgac ccaaatggat ttggcccaag caatccgagc acggacaagt aagacattgg
    28981 gtgtcatttt atggatcttg actgaattag ccattatggc aacagacatc gcagaagtca
    29041 ttggtgcagc aatcgccctc tacctgcttt ttgatattcc attggtaatt gccgtattta
    29101 tcactgtgtt agatgttttc gtccttttat tgctgacaaa agtcgggttt cgtaaaatcg
    29161 aagctttggt tgtctgcttg attttcgtca ttttattcgt tttcgtctat caagttggct
    29221 tgtctaaccc tgattggcac agtttgtttg ccggatttat ccctaacagt cacacattct
    29281 cagactcacc ggtcatcggc ggcgaaactc cgctgactgg agctttaggg attattggtg
    29341 caacagtcat gccgcataac ttatatcttc attcagcagt ttctcaaact cggaagatcg
    29401 atcaccaaga cgaagaagat gtagcacaag cggtacgctt ttctacttgg gattctaata
    29461 tccagttgtc aatggctttt ctagtcaatg cactgctatt gatcatgggt gtggctgtat
    29521 tcaaaaccgg ttctgtccaa gatccttcct tttttggtct gtatgaagct ttatctgatc
    29581 catcagctat gagcaatggt atcttgattg ctgtagcaaa atctggtatc ttgtctactt
    29641 tatttgctgt agcacttctt gcttctggcc agaactctac tattactggt acgttgaccg
    29701 gtcaagtcat catggaaggc ttcatccata tgcgtatccc aatttggcta agaagactag
    29761 tcacacgatt gctttctgtg attcctgtat tgatttgtgt tttgtttaca agtacaaaag
    29821 gaacgatcga agaacatacc gctttgaata acttgatgaa tgaatcccaa gtttttctgg
    29881 cttttgcatt gccattctcg atgattcctt tactgatgat gaccaatagc caagcggaga
    29941 tggggagccg attcaaaaat tcatttgttg taaaactact tggctggttc tctgtgatta
    30001 gtctgactta cttgaattta cgaggattac caggtcaaat cgaaagtttc ttcggcgagc
    30061 aagccacctc agctcaacta gcattggctg atcaaatcgc ttatgtaatc attgttcttg
    30121 tccttctcct gttggcatgg acgattggtg atttatataa aggaaacaaa aaatatgaac
    30181 agcgtttgca ggaaacgata gaagaaatcg agtagaaact gattctttta cacaaaggag
    30241 gttgtgtcag aagtgggcag cttcaagaaa taagaaggaa tttaagaaaa ttgcttttca
    30301 aatttttgtg aaatttcggc ttatttccga agaagttact tctggaacac cgtgtatcag
    30361 aggttgtgaa aaagctgcct tgcatcaagt aataagaaca gccaagtaaa aacagctttt
    30421 tatgttttta acttggttgg acttattacc gcagatgcaa gcttttgagc accgtttatt
    30481 cggaaaaagg aactgcgaca agacttttgt cacagttccc tttcctacga ttagtcaagt
    30541 aaaaggtgta agaaaaatag ctcataaacg aaagcgacaa aatcaa
//
LOCUS       DAZUJR010000030        29884 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.030, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000030 DAZUJR010000000
VERSION     DAZUJR010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29884)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29884)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29884
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.030"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            558..3197
                     /locus_tag="ACG804_001250"
     CDS             558..3197
                     /locus_tag="ACG804_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFS4832193.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(3365..4063)
                     /locus_tag="ACG804_001251"
     CDS             complement(3365..4063)
                     /locus_tag="ACG804_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HFS4832194.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            4281..5426
                     /gene="tgt"
                     /locus_tag="ACG804_001252"
     CDS             4281..5426
                     /gene="tgt"
                     /locus_tag="ACG804_001252"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HFS4832195.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            5523..5903
                     /gene="yajC"
                     /locus_tag="ACG804_001253"
     CDS             5523..5903
                     /gene="yajC"
                     /locus_tag="ACG804_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HFS4832196.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            6208..8805
                     /gene="adhE"
                     /locus_tag="ACG804_001254"
                     /gene_synonym="adhC"
     CDS             6208..8805
                     /gene="adhE"
                     /locus_tag="ACG804_001254"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HFS4832197.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            9034..10140
                     /locus_tag="ACG804_001255"
     CDS             9034..10140
                     /locus_tag="ACG804_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFS4832198.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            10157..11185
                     /locus_tag="ACG804_001256"
     CDS             10157..11185
                     /locus_tag="ACG804_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HFS4832199.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLEGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            11191..11670
                     /locus_tag="ACG804_001257"
     CDS             11191..11670
                     /locus_tag="ACG804_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HFS4832200.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            11686..12981
                     /locus_tag="ACG804_001258"
     CDS             11686..12981
                     /locus_tag="ACG804_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0031317 - tripartite ATP-independent
                     periplasmic transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HFS4832201.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            12992..13816
                     /locus_tag="ACG804_001259"
     CDS             12992..13816
                     /locus_tag="ACG804_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFS4832202.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPETP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            13981..14880
                     /locus_tag="ACG804_001260"
     CDS             13981..14880
                     /locus_tag="ACG804_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4832203.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(15006..15875)
                     /locus_tag="ACG804_001261"
     CDS             complement(15006..15875)
                     /locus_tag="ACG804_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFS4832204.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            16028..17488
                     /gene="rhaB"
                     /locus_tag="ACG804_001262"
     CDS             16028..17488
                     /gene="rhaB"
                     /locus_tag="ACG804_001262"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008993 - rhamnulokinase activity
                     [Evidence IEA];
                     GO_process: GO:0019301 - rhamnose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HFS4832205.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            17485..18741
                     /gene="rhaA"
                     /locus_tag="ACG804_001263"
     CDS             17485..18741
                     /gene="rhaA"
                     /locus_tag="ACG804_001263"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008740 - L-rhamnose isomerase activity
                     [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0019299 - rhamnose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HFS4832206.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            18755..19600
                     /gene="rhaD"
                     /locus_tag="ACG804_001264"
     CDS             18755..19600
                     /gene="rhaD"
                     /locus_tag="ACG804_001264"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008994 - rhamnulose-1-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019301 - rhamnose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HFS4832207.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            19602..19913
                     /gene="rhaM"
                     /locus_tag="ACG804_001265"
     CDS             19602..19913
                     /gene="rhaM"
                     /locus_tag="ACG804_001265"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0062192 - L-rhamnose mutarotase activity
                     [Evidence IEA];
                     GO_process: GO:0019299 - rhamnose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HFS4832208.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            19995..21146
                     /gene="fucO"
                     /locus_tag="ACG804_001266"
     CDS             19995..21146
                     /gene="fucO"
                     /locus_tag="ACG804_001266"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008912 - lactaldehyde reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HFS4832209.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEVSVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            21273..22031
                     /locus_tag="ACG804_001267"
     CDS             21273..22031
                     /locus_tag="ACG804_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HFS4832210.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIQTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            22131..22775
                     /locus_tag="ACG804_001268"
     CDS             22131..22775
                     /locus_tag="ACG804_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HFS4832211.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            22782..23789
                     /locus_tag="ACG804_001269"
     CDS             22782..23789
                     /locus_tag="ACG804_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PfkB family carbohydrate kinase"
                     /protein_id="HFS4832212.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            23805..24647
                     /gene="kduI"
                     /locus_tag="ACG804_001270"
     CDS             23805..24647
                     /gene="kduI"
                     /locus_tag="ACG804_001270"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008697 -
                     4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0045490 - pectin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HFS4832213.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            24667..25470
                     /locus_tag="ACG804_001271"
     CDS             24667..25470
                     /locus_tag="ACG804_001271"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HFS4832214.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(25719..26783)
                     /gene="fni"
                     /locus_tag="ACG804_001272"
     CDS             complement(25719..26783)
                     /gene="fni"
                     /locus_tag="ACG804_001272"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HFS4832215.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(26780..27865)
                     /locus_tag="ACG804_001273"
     CDS             complement(26780..27865)
                     /locus_tag="ACG804_001273"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HFS4832216.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            complement(27878..28855)
                     /gene="mvaD"
                     /locus_tag="ACG804_001274"
     CDS             complement(27878..28855)
                     /gene="mvaD"
                     /locus_tag="ACG804_001274"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HFS4832217.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            complement(28848..29792)
                     /gene="mvk"
                     /locus_tag="ACG804_001275"
     CDS             complement(28848..29792)
                     /gene="mvk"
                     /locus_tag="ACG804_001275"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HFS4832218.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
BASE COUNT         9423 a         5428 c         6611 g         8422 t
ORIGIN      
        1 aaaaagccga gctctcgata agctcggctt tcttgtacct cggaaggatt caaataaaca
       61 gaaatgattg taactttcca tcatacatgc aaagcacggt gttgaatttc ttcatgttaa
      121 acaaaaattt tgttttcgtt acatcttcaa catttgaaac atctcttgtt cctattcaat
      181 tttcagacgt ttacgttatt caattgttac gtatcgcatt acttcttgtt tcggatactt
      241 cgtgatccaa acatccatac gcattcacta tttataggtt tgtactctac acgcatgtct
      301 gggtgaaacc tgtacttcta acaactttgt ttgcttacac tgttctatcg agaaattctt
      361 ctgtctattt gatggtatcc tccttcctta catctatata atagcatcct ttggtagcgt
      421 ttgcaaatat aagcacttta aattttacgc tttcttaaca aataatcgat aagcccttta
      481 tttgaagtaa ataaaaaaag gatgttatag taaaataagt accttttttt gtacgaagat
      541 tttaaaggag gaataggatg gaagaataca agcagacaat agaagaagta aagaaggtaa
      601 cagaagcaga tccagatact gggttgtctt cacaagaagt ggatgaacgg cgaaaaaagc
      661 agggattgaa taaattcgat gaggcgccga aagaatcgat gatcaaaaaa ttctttcgaa
      721 gcttgtccga ttttacaacg atcatccttc ttgtagcagc ggtgatttcc ttttataccg
      781 catttgctac agaacatggg gatttatttg aaggactgct gatcatcgct atcgttgtga
      841 tcaactcggt attggcgatt gtccaagaag gaaacgcaga aaaagcactg gaatccttgc
      901 aagatatgaa taaacaaacg gcaactgtca tacgagacgg caaagtgacc actgttgagt
      961 cagagcaact ggtagtgggt gatattcttg ttttagagtc cggtgatgct atttctgccg
     1021 atgcccgttt gatcgaagca tcacaattac gtgtagaaga atcggcgttg actggagaaa
     1081 gtgaagcagt tgaaaaagat gcagcattta ttgctgaaga agatgagtca ttaggtgacc
     1141 aacttaatat ggtatttaaa ggatgtacgg ttgctgcagg tcgtgggaaa gcgatcgtca
     1201 ctgccattgg catggctaca gaaatgggta agatcgcgga tcttttgaac gaaaatacta
     1261 tgcaaaaaac acctttacag gtccgattga atcagctagg caaacgaatc agtatgatcg
     1321 ctttagcggc tgcggcttta gtatttgtga ttggtgaact gcaaggagaa ccactccttg
     1381 agatgttcat gacttcgatt tccttggctg ttgcagctgt accggaaacc ttgactgtta
     1441 ttgttacgtt gacacttgca tacggtgtgc agaagatggc gaggaaacat gcgatcatcc
     1501 gacagttgcc agcagttgaa acgctaggaa ccgctaatgt tatctgctca gacaaaacag
     1561 gaacgctgac acaaaatgaa atgcgcgtcc gccgggtatg gagcaaagaa gatgaagtaa
     1621 cgaatatcga agattcaatg acgaacagcg cgatggaaat attgaaaatg gctgcactat
     1681 gtacagatgt gacggtcgag caagaagatg acgaccttgt tatcaaaggt aatccaacag
     1741 aagtagccat cgtaagggct gttgaagaga attatcatac aaaggcagaa ttagaagaaa
     1801 aatatccacg agtaaacgag cttccttttg attctgaacg aaaaatgatg acaacagttc
     1861 accaaatggg cgaaaaatac atctcaatca ccaaaggagc attcgatgtt cttgctccgc
     1921 gctttagttc aggcgatgta gaacaagcgg cgatcgttaa tgatcgcttt ggtaaacggg
     1981 cactgagagt gattgctgtt ggttatgcta cttatgacga agaaccgcaa gatatttctt
     2041 ctgaagcact ggaaaaagac ttacgtttga ttggtctgat cggaatgatc gatccaccac
     2101 gtccagaaag taaaggagca atcaagcgag cgaaaaaggc tggcatcaaa acagtcatga
     2161 tcactggaga tcatgtggtg actgccagtg ccatagcgaa agaattaggt atcttgaatg
     2221 atccgtcaga agcactttca ggatcagaac tgcatcaatt atcagacgaa gaattagatg
     2281 cgcgtgtcaa agctctctct gtctatgctc gggtaacgcc agaagacaag atccggatcg
     2341 tcaaatcttg gcaacgtacg ggtgcagtcg tagcgatgac tggggatggt gtgaatgatg
     2401 caccagcgtt gaaagcaagt aacgttgggt gtgccatggg gatcacagga acagatgtgg
     2461 cgcaaagtgc cgcagatatg attttgacgg atgacaactt tgcgacgatc gtagacgctg
     2521 tcagtcaagg acgttcggtt tatcagaata ttcgtaaagc tatcaacttt ttgctaagct
     2581 gtaatatttc ggagatcttt attgttttga ttgcgatgct gttaggatgg ggagcaccat
     2641 ttacagctgt gcaactactg tttgtcaatg tagttgctga tggacttcca ggatttgctt
     2701 taggaagaga gccagcggaa cacggcatca tggatcagcc acccattccg aaaaatgaag
     2761 ggatctttgc tcgaggttta ttgcaaaaaa ttgccataaa tgcaggggtc ttcaccatcg
     2821 taaccttgtt tggttattat ttaggtagtt atgtcgatac tatcagccca tgggtagacg
     2881 caagtcagca tgtcggtcaa actgttgcat tcttgatctt agcttattca tcgattctgc
     2941 atgtgttcaa tgtacgcagc agccaatcga tcttcaaagt caatttagcg accaataaag
     3001 ctttggtaga aatggcgtta ctggcattag ctattacaac ggctgttgct ttgctgccat
     3061 ttacgcaaga actattcggc ctagtacaca tcagtttgaa tcactggttc ttggtaggga
     3121 ttttatctat cgtaccaatc gcggtgaatg aactgatcaa gttccatcga ttaccggaag
     3181 cagaagaaga ggaatgatta actgtttcta agttgatttt ctttttactg gaactataca
     3241 aaaaggaggt gtgacatgaa tgttgtcaca cctccttttt gctaatgggc tgaatgtttc
     3301 ttttactgcc tctcgataaa cggtgttctc ctgccacccc ctcggtcaca agtcacactc
     3361 tcttttaaat atcttttggc aattgttcat aaaatgctgc ttttgttgca gaaatgtatg
     3421 ggctgagcca tagataacca ataccagcag ttgctaatgc taagatatgc cagccgataa
     3481 atgaaagatc taaccagaaa agttgtcctt tataaccatc catcaatttt cgacttgcag
     3541 tgatcgtatc cagtacttta ggtgtttgtc ctgtttcttg gacgatatcg tagtaaataa
     3601 aatagctttg agaataagaa tagcttttaa tgattccagg aataactaat agcaaacccc
     3661 ataatgttgt aaagatcgag atcagcacag ctaagctgat cactccgccg ataaacaaac
     3721 ctttgaatcc acgaaatgca tctttgaatg gttcgatctg atctttttgt ccacgtaaaa
     3781 tatcaagata agtccaagaa ataccgctca tgaacaaagc gctaatgatg ctggaaataa
     3841 ttccgccacc gcctcctgaa ctaccgcctc ctgaagttgt cgcttctgag acgctcgctg
     3901 atccatcata tatggtggtg gcaaacaaga taataggaat cataataaga agaatagtag
     3961 caataccaat caatgtaggg attagattta gtaaaacagc ttgtccccaa cgtcctttta
     4021 gactctcttt tgcttggcgt tttaattctg cagaagattg catgattttt ccctcctttt
     4081 ctttaataac accaatatac catgtatcaa aaaatatttc tgtcataatg tttttctttt
     4141 ttttgttatt cataaaaaaa ggataaaaaa aagaatatta aataaagtag aaggaagccg
     4201 agggaacttg caaaaagcac ttgaaacgat tatgatggtg ggagttgtca agatatttta
     4261 tatagaaagt agggaaatga atgacgcaac ctgccattcg ctatcgttta atcaagaaag
     4321 aaaaacatac tggcgcgcgt ttaggggaat tgatcacgcc acacggaact ttccccacac
     4381 caatgttcat gccagtagga acattagcta cagtaaaaac aatgtcccca gaagagttga
     4441 aagaaatggg tgctggcgtt attttaagta atacatatca tttatggcta cgccctggtg
     4501 aagacttagt agaagaagct ggcggactgc ataaatttat gaactgggat caaccgattt
     4561 taacagattc aggcggcttt caagtttttt cattaagtga tatgcggaat atcgaagaag
     4621 aaggcgtgca tttcaaaaat cacttgaacg gttcgcgtat gtttttatca ccagaaaaag
     4681 caatcaacat ccaaaataaa ttgggctctg atatcatgat gagttttgac gaatgtccac
     4741 cattcgatga aagttacgac tacgtgaaaa aatcagtaga acgtacgtct cgatgggcag
     4801 aacgaggatt gaaagctcat gctaatccag accgtcaagg attatttgga atcatccaag
     4861 gagcagggtt tgaagatctt cgtcgtcaaa gcgcgaaaga tctagtcggg atggatttcc
     4921 ctggttactc aatcggcggg ttatctgtcg gggaacctaa atcagaaatg aatcgtgtat
     4981 tagaattcac tacaccgttg atccccgaaa acaaaccacg ttacttgatg ggtgtcggtg
     5041 ctgctgattc attgatcgat ggtgttatcc gtggagtaga catgtttgac tgtgtcttgc
     5101 ctactcgaat cgctcgaaat ggcacatgta tgacttctca aggccgtcta gtagtgaaaa
     5161 atgcgaaata tgcccatgat ttccgtccaa ttgatgagaa atgtgattgt tatacatgta
     5221 aaaactatac acgtgcctat atccgccatt tgatcaaatg tgatgaaaca tttgggattc
     5281 gtttgacttc ttaccacaat ttatacttct tgttgaatct aatgaaacaa gtacgtcaag
     5341 caatcatgga tgataatttg cttgaattta gagaagcctt ttttgaagaa tacgggttca
     5401 ataaagaaaa cgcaaaaagc ttctaaagga aaatctttta aaaattaagt aaaaaactag
     5461 tgttatcagc atttttctgc taaagtgttt tttgtagata cagaattagt gaggtgaaaa
     5521 aaatgggaac attaccaatg cttgtgatgt ttatcgcgct attagcaatg tggtttttta
     5581 tgtcacgttc gcaaaagaaa caacagcaag aacgtcaaaa cttgttagat agcatgaaac
     5641 caggtgattc agtcgtaacg atcggcggat tacatggagt tgtttcagaa atcgacaatg
     5701 acaaacggac agttgtttta gactgcgaag ggatcttcct tgagtacgat cgtgcagcaa
     5761 tcaaaacggt caaaccaggg actgtcgtaa caaatgatgc aacgactact gttgaaacaa
     5821 cagaagaacc agctgagaca gttgaagtaa aaactgaaac aacagaaacg ctggaagaga
     5881 cagaagagaa ggaagaaaaa taagtatcaa agcttattta aagacgaggt agggcagaaa
     5941 gatgtcctac ctcatttttt attcaaaaaa gaaagagata agagcatggg atatattgct
     6001 caatattgaa taatcgggtg tgtcatataa ataataataa ataactttat atatttttct
     6061 atacaaacac ctgtaaataa agcaatttta tatttaaaaa taactgtgaa aaaaatcaca
     6121 aaaaagtgtt tacatagaaa aataaatatt gtatgatata catgtgaatt atttaacaaa
     6181 taaccatgac ccattaggag gataatgatg gctaaagtaa tagaaaaaga aaaaacgaag
     6241 acaattgacg tacaagcaat gattgatgat ttggcagaaa aagcaaatgc agcattgaaa
     6301 gaaatggaaa gctttgatca agaaaaagta gaccatatcg tgcatgaaat ggcaatggca
     6361 gctttggatc aacatatgcc attagcgaag atggctgtag aggaaacagg ccgcggtgtt
     6421 tacgaagata aagcaatcaa aaatatgtat gcgtccgaat atatttggca taatatcaaa
     6481 catgataaaa cagttggtgt gatcaatgaa gatgtccaaa aagggttgat tgaaattgct
     6541 gaaccagtcg gtgtggtttg cggagtaact ccaacaacga atccgacttc cacaacgatt
     6601 ttcaaatcaa tgatcgcgtt gaaaacaaga aatccaatcg tttttgcttt ccatccaagt
     6661 gcccaaaaat cttctgcaga agcagcacga gtggtacgtg atgctgctat cgctgccgga
     6721 gctcctgaaa attgtatcca atggatcgaa catccttcga tcgaagcgac ttctatgcta
     6781 atgaaccatc caggtatcgc gatcgtctta gcgacaggtg gagctggaat ggtcaagtct
     6841 gcttactcta caggaaaacc agctttaggt gtaggtccag gtaacgtacc agcttatatt
     6901 gaaaaaacag caaaaattaa acgtgcagtg aacgatttga tcgtttcgaa aacatttgat
     6961 aatggaatga tttgtgcttc tgaacaagct gtgatcgtgg ataaagaaat ctatgcagca
     7021 gtaaaagcag aattccaagc acaccaagtt tatatcgtaa aaccagatga attgcaaaaa
     7081 ttagaagatg cagtgatgaa cgaaggaaaa tatgcggtca atccatcaat cgttggacat
     7141 tctgcgatgg aaatcgcaaa attggcagga atcagtgtac caaaaggaac gaaaatgctg
     7201 attgctgaat tggaaggcgt aggcccagat tatccgctat caagagaaaa actttctcca
     7261 gttcttgcca tgatcaaagc taacaacacg gaccatgcgt ttgatttgtg tgaaggtatg
     7321 ttgaatcttg gaggattagg acatacagca gttatccatt cagaaaacga agagttgcat
     7381 gtcaaattcg gtcttcgaat gaaagcttgt cgtattttag tgaatacacc atctgcagaa
     7441 ggcggcatcg gtgatatcta taacgaaatg attccgtcat tgactttggg atgcggttct
     7501 tatggtaaga actctgtttc tcgtaacgtc tctgctgtaa acttaatcaa tgtcaaaact
     7561 gtagcgaaac ggagaaataa catgcaatgg ttcaaattac cgccaaaaat cttctttgaa
     7621 aagaactctc tattgtactt agagaaaatg gaaaacgttg aacgtgtcat gatcgtttgt
     7681 gaccctggta tggtccaatt cggttactgc gatacagttc gtgaagtatt ggcacgacgt
     7741 aaaaatgatg tgaagatcga agtcttctca gatgttgaac cgaacccatc gacaaatacc
     7801 gtatacgcag gaacgaaact gatggcagac ttcaagccag atacagtaat cgctcttgga
     7861 ggcggttctg caatggacgc agctaaggga atgtggatgt tctatgaaca cccagacaca
     7921 tctttctttg gtgcaaaaca aaaattcttg gatatccgta aacggacata taagatcgac
     7981 aaaccagaaa aaacacaatt cgtatgtatc ccgacaacat cagggactgg ttctgaagta
     8041 acgccatttg cggtcatcac tgacagtgaa acacatgtga aatatccgtt agcagattat
     8101 gcattgacgc cagatgtcgc aatcgtcgat cctcaattcg tcatgtcagt tccagcatct
     8161 gtcacagcag ataccgggat ggatgtgtta acacatgcaa tcgaatccta tgtttcagtc
     8221 atggcttcag attatacacg tggattgagc ctacaagcaa tcaagttagt ctttgactat
     8281 ttagaaaaat cagtaaaaac acctgatatg gaatcacgtg aaaaaatgca caacgcttct
     8341 acaatggctg gtatggcgtt tgctaacgca ttcctaggta tttgtcactc agtcgcacat
     8401 aaaatcggcg gggaatacgg gatccctcat ggacggacaa atgcgattct tttaccgcat
     8461 attatccgct ataatgcaaa agatccacaa aaacatgcga tgttccctaa atatgactat
     8521 ttccgtgcag atacagatta cgcagatatc gcaaaattct taggtctgaa aggcgaaaca
     8581 acagaggaat tagtcgaagc tttagcaacg gctgtttatg aattaggaaa atctgtcggc
     8641 atcaacatga gtctaaaagc tcaaggagtc acacaagaaa cactagatac aaccgtagac
     8701 cgtatggctg aattagctta cgaagaccaa tgtacgacag ctaatccgaa agaaccattg
     8761 atctctgaat tgaaacagat catcattgat gcttacaacg gataagcaaa agaaagcgta
     8821 gaaaaaagat aagaaaatag atgaaaaaga acttggaaaa cgttgtttct ccaagttctt
     8881 tttttaattt ccaagtaact gaaagttact tttgttattt aacatttagg tcaattttag
     8941 acagtttttg ttcaaaaagc gatatttata gtggacggta ttactgctat attaaggata
     9001 taaaatgaaa gcgtttaaaa aggtggcgta aagatgatta ttaaagaaga gatttttgta
     9061 cctaaagaat tagtgaaaga aaaaattgac ctgctcgttg aaaacctgac aacgatcaaa
     9121 gacgataatg gtgaattttt gttggacttt gatggactga aagtagatga caaaagctgg
     9181 acagtgtgga attggccaca aggtgtcggt ctatatggta tttataaaaa ttaccagatg
     9241 acaaaaaatc ctcgcgctta tcaagtggtc aatgaatggt ttgaggatcg tatggaagaa
     9301 ggcgctccgc ccaaaaacgt caatacaatg gcaccgctat tgactatggc ttacttgtat
     9361 gaagacacga aagattcacg ctatttgcct tatttagaac aatgggcaga atgggtcatg
     9421 aatgacatgc ctcggacaaa tgaagacggg ttacagcatg ccacatatgg accggaaaat
     9481 aagaatcagt tgtgggacga tacattgatg atgacagtgc ttcctttggc aaaaatcggg
     9541 aaactgttga atcgcccaga atatttagaa gaagctcgtt accagtttat gatccatatc
     9601 aaatacttga tggataaacg aacaggattg tggtatcacg gctggacgtt tgaaggaaat
     9661 cataactatg ccgaagcatt ttgggctcgt ggaaactgct ggttgacgat tgctattcca
     9721 gagatcattg aaatcttaga attatcgaaa gaagatgcat tgcgcaaatt attgatcgaa
     9781 acacttgaag cacaagtgcg tgcattaaaa acttatcagt ctgaaagcgg tttatggcat
     9841 acgttgttgg atgatccttc ttcttacgta gaatcttctg caactgcagg atttgcttac
     9901 ggtattttga aagcggtcca taaacgttat ttaccacaag aatataaaga agtcgcttat
     9961 cgtgctatcc aaggattgct tgaacaaatc gatgaaaaag gagaagttca aaacgtttca
    10021 atcgggacag gaatggggga cagtttagat ttttatcgga atatcggaat cacagcaatg
    10081 ccttatggac agtcgttaac ggtgctttgt ttgacagaat tgctcgtctc ttattgttaa
    10141 aagaaaggaa acccatatga aaaaaacatc actgctgttt gcagcaagtt cgcttagcct
    10201 aggtctgcta ggtctaagcg gctgcggaaa taattctagt gtggcaactg tcgcagatgc
    10261 agatgtaaat gagatagtta ccttgcgctt tgcttatgca agcaacagcc agccagtaat
    10321 tgatgcaatg aatgaatttg ggcgtttagt aaaagaaaaa acagatggtt ccgtacagat
    10381 ccagtatttc ccagatggac aactgggtgg agaacgtgaa ctgatcgaat tgacacagtc
    10441 aggagcagta gatttcacaa aagtaagtgc ctcagcgttg gaaagtttct ctaaagatta
    10501 ttcgattttt tcagttcctt atctattcaa tgatgaagaa catttcttta aggtgatgga
    10561 taatgaagaa ataatggagc caatctacca atcgaccaaa aatttaggat ttaccggatt
    10621 gacctattat gattctggtc agcgcagctt ttatatggta gacggtccga tccatacgcc
    10681 ggaagatttg gagggaaaga agatccgtgt gatgcaaagc gaaaccgcta tcaaaatggt
    10741 agagctttta ggcggttcgc ccgtacctat gggaagtgat gaagtgtaca cgtctcttca
    10801 atccaatttg atcaacggat cagaaaacaa tgaatttgtc ttgtatacag ctggacatgg
    10861 tggtgtggct aaatactatt cctatgatga gcatacacgt gtgccagata tcatcatcat
    10921 gaatgatgcc atcaaagaac agctaactga tgagcaggaa aaagccattg aagaagcagc
    10981 gaaagaatca acggtttttg aaattgaagc ttttgcaaaa gcaattgaag aagaaaaagc
    11041 tttagcacaa gaagaacatg gagtccaatt caatgatgta gataatacac cgtttcgaga
    11101 ggcagttgcc ccacttcatg atatattcaa aaacgatcct acctacaaag acctttatca
    11161 aaagatccaa gagcaaggag cgtagctgtg atgaaaatga ttttaaacaa ggtattagag
    11221 atcctgggag ctgttttgct tgttgggatg gtcgctgttg ttttatggca agtattttcc
    11281 agaacggttt taggaaatcc aaatacggtc acggaagagc ttgttcgatt cggtcttgtc
    11341 tggtttgcca tgttgtcttc cgcgtatgtt gtgggacaaa aagcacattt agccgtaacg
    11401 gttttaagtg aaaaattaac tggcaaaaaa agtaaaattt tagaagttgt tgttcaaagt
    11461 ttatttctgg tatttgctgc gatgatcatg gtgtatggcg gatggaatgc tgtcacattg
    11521 acaatggggc agatctcgcc ttctttaagt attcctatgg gatatgttta tctgtcagta
    11581 cctgtatcgg gggtactcat cattatctat agcctgatca atctaatcga tacattaagc
    11641 aacaagccag caattcaaga aaaaatataa aaatggagga ataaaatggc aatagaagcc
    11701 ggattagtgt tattttttgt atttgttgtg ttgcttgtat tagggatgcc gattgctata
    11761 agtattgcat tctcatcgat gatgacttta ttgttagtta taccgtttga tgtttctgct
    11821 tttagttcag ctcaaaaaat ggtgggaagt atcaatagtt tttcgctgat cgctattccg
    11881 tttttcgttc tctcgggcat tatcatgaat aatggaggga tagctaagaa actagtggat
    11941 tttgcgatgt tgttcgtcgg gcgcgtgccg ggggctttgg ctcatacgaa tgtgttaggg
    12001 aatgctttat ttggttccat ctctagctcg gccattgccg cttctaccgc gattggcgga
    12061 gtgttgatcc ctcagcaagt ggaagaagga tatgaccgga agtttgcgac agcggtcaat
    12121 atcgcgtcag ctccgacagg tatggtcatt cctccaagta ctgcttttat catgtattca
    12181 cttgttgctg gtggtgcttc gatctctgct ttgtttatgg gaggttatct cgtaggcgct
    12241 ttgtgggcgc taggaatcat gctagtagca ttcatcgttg ctaaaaagaa taaataccct
    12301 gttgtcgaaa aaggacagat ggctcatgct ggaaaaataa taaaagaggc gattcctagc
    12361 cttctattga ttgtcatcat tatcggtggt atcttgacgg ggatatttac agcagtagaa
    12421 gcttcagcga tagctgtcat ttactccctg ttgattgcta tgttttacta taaaacggta
    12481 aaactaaaag atatacctaa tatgttgttt caatcagtag caatgtcagg gacgatcatg
    12541 ttcttattgg ctacttcttc catgatgtct ttcgccatgg cgtttaccgg tattcctcag
    12601 gcaattagtt cgttgattat gggcgtaacg gataataaat ttattattct gttattagtc
    12661 aatcttgtgt tattactggt gggtatgttt atggatgtgg cgcctgctat cttgattttt
    12721 acaccaatat ttttaccaat cgtcacaagt gtaggggttg atcctgtaca ttacgggttg
    12781 ttttcaatca tgaatctgtg tgtaggctcc atcacgccgc cagtaggtac aggactatat
    12841 gtcggtgcaa gtgtaggagg cgtaaaagca gaggcaatgc tgaaaccgct tcttcctttt
    12901 tatggggtta tcttagtcgt cttgtttttg attacttact tcccgcaaat cgtcatgtgg
    12961 ctacccaata tgctgagtta ggagaatagt tatgttgaac attacaatta gaggacatga
    13021 tctttccgaa gtccaaacga tagaagatct tgcagaaaaa acaaaagaac aagggattca
    13081 tacactgcag ctcgccttag gtctttcgtt tcctgaaaca ccttctggcg caaatgagat
    13141 caattctggg atgggaaatt atgtcaaacg agttttagaa aagcaagaag tgaccgtagg
    13201 aattttaagt tgctatatca atatgattca tccagattta acgatacgac aagagttgct
    13261 gacaaagttc gagcagtatc ttcgctatgc ttcttccttt ggtgcgtcga tggttgcttc
    13321 ggaaactgga tgtgttttgc cggaaatcca atatacggaa gaaaatttca cagatgaagc
    13381 atttgctgaa gctgtgtccg ttatccgtcg cttggtaaaa gctggagaaa aataccaaat
    13441 gatggtgggg atagaaccag gtttgaatca tccggtgtat tctttagcaa gggtagagca
    13501 gctgatccaa gcagtagatt cggactatct aggaatcatt ttagatccga ccaatttgat
    13561 cacaagtagt gattatcaag aacaagtcca attggtagaa gaagcttttg aacgttttgg
    13621 tgaaaagata tgtgcggttc atttgaaaga ttttcgtgtc gaacaggaaa aaatcgtgcc
    13681 ggtaaatttg ggagacggtg tgatcgagta cacaaaaatc aaagaaatca tcatgaagaa
    13741 tcgtccgtac ctgtatgtgg ttcttgaaga aacaaaagat gatgggattc gttatggaag
    13801 aagtcttctt gaataatgta aagaagacgt tggttaacta atatttagaa tggagggggc
    13861 ggggctagaa gatgccacgt ctcttctttt ttataagagt atataaaagc agctcttttt
    13921 gattacaaaa aacgtggtat aataaaattg tgcataagtg aacaaaagga ggtgcggcac
    13981 atgctccaaa agaaaatcag cggtgaacaa gtcaatacga tggtttctga tcagtatgaa
    14041 atctatcatg tcaaagatgt cgtcagccaa aataaaacga tctatcatca tcatgatttc
    14101 tatgagatcc atgctacatt aaagggagaa gcgacttttt atttgaacgg acgacaattt
    14161 acgatcaaag caggaagtgt gctgctcatc cattccaatg atttgcatcg tatcgtccgc
    14221 caatcttcag atgtattcga gcgtgtctat atctttgtca ccccttcttt tctagaaagt
    14281 cgttccacgc catggtctaa tctatcggct tgttttcaac caatgggaga gaagaggagt
    14341 cgtgtattgc aaatagaaca ggaagtattg aagcaaaaat tatcatttat cgaccatcct
    14401 cctgataaaa aaatttacgg tgaagacata aaatatgaac aagctctggt agaatacttg
    14461 atttttctca atcaagttgt acaaaaagaa gagagtgcgc aagaacagaa tgctgtagtt
    14521 cctaatgagc gtgtggaaca aatgttacaa tatatctcaa aaaatttatc tcatccgctt
    14581 tctttagagg aaatggaaaa gcagtttttt gtcagcaaat accatatcac acgagaattt
    14641 aaaaagtaca ctggatttac gtttcatcag tatgtaatga agaaaaagct gatctatgcc
    14701 aagcacttgt tgcgagaata ccgcagctct agtgctgtat atagtaaaag tggtttttct
    14761 tcttatccgc attttctgaa agcattcaag agagagttcg gcataacgcc taaagaattt
    14821 ttgaaacgtg atacacagaa acagttggtt cattatgaac attttgaaga tgaacaatga
    14881 gaatgatcac taaaaaataa ccgcagtagc tgctgttgtt tacatagaag cagaaactgc
    14941 ggttatttta tttttatcta tatatttcaa aatattttga aaaaatgacg tacatattat
    15001 atgaatcagc tgaatttacg aaagtctctc ggcgatagtc ctgtttttgc tttgaacagg
    15061 cggctaaagt aagcaaaatt ctcaatccct atttcttcgg aaatcattcg aaccgtaaat
    15121 tctgtatacc gaagaaggtc tttagcgtaa gaaagttttt tgctgatcaa ataatcgatt
    15181 ggtggagaac cgataaattt ggaaaaatct ttgctcagct gatatttatt caataagaat
    15241 tgttgttcta attgatcaag tgtaatcgtt tctttgaaat gttcgtctaa gtattgcttc
    15301 agtttgtaaa cgtaggcggg aatatcctct tcttcgaaat ctagctgata cttttgcaaa
    15361 atcagttcat tcagcaactc gtggatagct acagaggact ggaaatcggt acgggcattc
    15421 gtgccttgtt gcatgtggat caattctgtg atcaaatggt ggatcttgtt ttctgatgga
    15481 tcccctgttg aatggaaggt gttatggccg tcttttgtga actcctgata aaatgattgg
    15541 acgttctgac cattcaaatg gatccaatcc atttcccatg gttcttcgct gatcgtttga
    15601 taacgctgat attcttggca gtcaataaaa aataagtctc cagcttttag ctgttgctga
    15661 ttatcattat atgtaagcga acctttgcca gacaaagtaa actttatcaa gtaagaaggt
    15721 aaatgtgctc gttcagtata gtaagggatt ggtgctttga agtaaccgat ttcttggata
    15781 taaaaaaata aattcctgct tctttgtgta ggcgtcaaga tcactctttt tgagtcttcc
    15841 gaccatgagt ggttggcttt ttcccagtaa tccatgtaaa cactcccaac ttgtcaagat
    15901 aatgcaatta tataccaaaa tagtgtgaag caaaatataa gattctgtat tatgatagca
    15961 ttgttaataa atgataacgc tttattaata aagtgctaat caacaataaa gtaaaagagg
    16021 tggagaaatg aatccaacat ttgttgccat cgatatcggt gcatcaagcg gacgactaat
    16081 gaaaagtacg agggatgcaa aaggttcttt gatcttggaa gaagtacacc ggttcaaaaa
    16141 cggctttcgg aacaaagacg gtcacgatcg ctggaagatc gattatctta tcaaagagat
    16201 tttgattgga tttgaaaaat taaagcagac agggattgat cgcctttttg cggggatcga
    16261 tacatgggca gtcgattact gtctgattga tgaacaaggg gatcggataa atgatccgat
    16321 tgcttatcgg gacaagcgta ccaatggagc agtagaacag ttttctgaaa tctattctct
    16381 agataagttg tatgagcaga cagggattca gatccagcct ttcaatacct tgttccaatt
    16441 gtttgctgaa gaaaaagaaa atttggcaaa agcacataaa ttgttactga tacctgatta
    16501 tttagggtat gtctttactg gtaacatggt gacggagaaa actaatgcat ctactatgca
    16561 gctgctgaat gcagggacaa aagaatggga aatagaactt cttgaaaaaa tcggtgtctc
    16621 gaaggaatta tttccaccat tgacagagcc gggaacgata ctaggagatc tgcaaaaaga
    16681 acaattttca aaatatgatt tgccagatgt gacctttatc acagtagcaa gtcatgatac
    16741 ggcgtcagct gtattaggaa cgccaggtca aggagaacgt tggggttata tcagcagtgg
    16801 gacatggtcg cttttaggga ttgaaacaaa gatcgccaat gtttctcgca atgctttttc
    16861 tgaaaattat acgaatgaat ggggtgccca taacacggtg cgttttttga aaaacatcat
    16921 ggggatgtgg ttgatccagg aagttgcccg aatgcaagag tacgagtaca gttatgcgga
    16981 attggcagag cttgctgcaa aagaaaaacc gctgcagcaa gtgatggaaa tcaatgaccc
    17041 tcgatttttg aatcccccaa atatgataga agagattcag caatactgtt ttgaaacaga
    17101 gcagccagtc cctgtctcat cgggagctat cgctcgttgt gtgtatgata atcttgctct
    17161 ttgttacgca caagagctga tcaaagtaga acacttaact ggaacgaaat tggaaaagct
    17221 gcacatcgta gggggcggat cgaataatcg tctactgaat caattgacag cagattatgc
    17281 cggaatcatt gtagaagcag gacctagtga agccacagca atcgggaatg ttgccatgca
    17341 aatgctcagt acaggtcagt tttcgaatat agaacaagca agaaatgtaa tcaaacagtc
    17401 gtttccatgt gaaacttttt acccagatga aaataagcaa aacacgatgg aatggtacgt
    17461 gaataaaatc aaaggagtaa tcgtatgaac acgattgaaa gaaattacga acaagcaaaa
    17521 gaaaaatatg caactatcgg tgtagataca gatgctgtac tagaaaagat acaggacatc
    17581 aaaatttcta tgcattgctg gcaaggagat gatgtcaaag gtttcttgac accggatggc
    17641 gaattgaccg gtggaatcat ggcgacaggg aattttccag gagccgcacg aacacctgaa
    17701 gagcttagac aagatctgga gaaggcttat tcgttgatac cgggcaaaca caaattgaac
    17761 cttcatgcta tctatttgga tacagaagaa tctgtcgatc taaatgaaat tgagccgaaa
    17821 cattttgaaa aatgggtaga gtgggcaaaa aaagaagaaa tcggtcttga cttcaatccg
    17881 actttctttt cgcatccaat gatgaaagac ggctttacat tggctcatcc agataaagaa
    17941 gttcgtgaat actggatcga acacgggaaa agaagccgca aaatcgcgga gtactttggg
    18001 aaagaaactg ggcaaacaag tatcaataac ttttgggtac ctgatgggat gaaagataat
    18061 ccgattgatc gttttacccc acgggaacgt ttaatggaat cactcgatga aatttttaca
    18121 gaagagttag atgaacggta tgtacaagat gcagtagaaa gcaaactatt tggtttaggc
    18181 gctgaagctt atacagtcgg ttcccatgaa ttttatatgg gttacgggtt gactcgtgac
    18241 aaacttgttt gtctagatgc tggacatttt catccaacag aagtgatttc caataaatta
    18301 tcttcattag ctttattcag caaaggaatc atgttgcatg tttcccgtcc agtgcgttgg
    18361 gattcagacc atgtggtttt gatggatgat gaattgcagg aaatcgctaa agaattagtc
    18421 cgtaacgaat tgttggaaaa aacaaatatc ggtctggatt tctttgatgc aacgatcaac
    18481 cgtatcgctg cttgggtcat cggtacgaga aatacacaaa aagcactgct gaaagctatg
    18541 ctggaaccag ttgagcgatt gaaagaaatg gagctggctt ttgactttac ttcaagaatg
    18601 gcttatacgg aagaattgaa agatttcccg tatgccgatg tatggaatta tttctgttac
    18661 aaaaatcaag ttccagttgg tttggattgg ctggaagaag tccaggaata tcaaaaagac
    18721 gtgttggaat taagaaaata ggagtgtggc tatattgaaa aaaatagata ttttacaagc
    18781 gccttatgtg aaagaaatga tcgaaacgac gtcgaatctt tatcgcttgg gatgggatga
    18841 aagaaatggc gggaatattt cttatttact aaaagaagaa gagatcacac cgttcttgga
    18901 tcctgaaaaa gtgatccgcc gcatctcgat gatttttgat gccagccgtt tagcaggatg
    18961 ctattttatt gtaactggtt caggaagata ttttaaaaat gtagcgagcg aacctgccga
    19021 gaatcttgga atcgttcgag ttgctgaaga tggcaaaaca ctggaacttt tgtgggggct
    19081 ggaaaacgaa tgccttccta caagcgagtt gccaagtcat ttcatgagtc atatcgcccg
    19141 tttagaagta gacccagata atcggatcgt tatgcattgc catgctagtc atctattagc
    19201 gatgagtttt acgcatgaat tagacgaacg ttcctttagt cgtacgctat ggcaaatgtg
    19261 tacggaatgc ttagttgttt ttccagaagg aatttccatc attccgtgga tggttccggg
    19321 aacaaatgag attggggaag caacagctga aaaaatgaaa gaaactcgat tggttttatg
    19381 gccacaacat ggaatctacg ggtcaggaaa agacatggat gaagtctttg gtttgatcga
    19441 gacagcagaa aaggcagcag aagtctatac gtacgtcaaa gcgcaaggac caatcttgca
    19501 aacaatcacg gacgaaaacc tgtggcattt agcagatgcg tttggtgtca ctccaaaagc
    19561 aggttatttg gaggaagttc atacgaaagc aggtgtctga catggtgaaa aaagcttttt
    19621 gcatgaaagt ttacccagaa aaacaagaag aatacaaaaa aagacatgat gaactttggc
    19681 cagaaatgcg tacagcactt cgtgaacacg gggtcatcga ctattcgatc tatcttgatc
    19741 cgagtacaag tttgttattt ggttacttag tgatcgaaga tgaaaagtta tgggaaaaaa
    19801 tggcaaatac atctatcaat caaaaatggt ggaagtacat ggaagatatc atggagacaa
    19861 atccagatgc ctctccagtc agttgggaat tgatgccagt ctttgaactg tagcaacaag
    19921 caactgggca accggttgct tggggttctt tcgtttttat tgtgaaaaaa aatacaaatt
    19981 aggaggaata gaaaatgagt aatcgaatga ttttaaatga aacatcgtat tttggaaaag
    20041 gagcgattga gtcgatcgtc cctgaatttc agcagcgagg attcggcaaa gcagctgtca
    20101 ttactgacaa aggattgatc gagcacggta tagcaacaaa agtaacagaa cttctagata
    20161 aagcagcaat cgcttatgct ttatacgacg ggatcgtacc taatccaacg atccaaaatg
    20221 taaaagatgg agtggctttt gttaaagagg cagaggcaga ctgtttgatc gcaatcggtg
    20281 gaggttcgcc aatcgatacg gcaaaagcca ttgggattat tttgacgaat ccagagtttt
    20341 cagacgtcat tagtttagaa ggtgttgctg atacgaaaaa tccatgttta cctatattag
    20401 ctataccaac gacttctgga acagcagcag aagtaacgat caactacgtc atcacagatg
    20461 aagtaaatca ccgaaaattt gtttgtgttg atcctcatga tatcccaatc gtcgcgttca
    20521 tcgacagcga tatgatgatg ggaatgccga aaaaattggc tgcatcaaca ggtatggatg
    20581 ctatgacgca tgctattgaa gggtttatca caaaaggcgc ttgggaaatg actgatatgc
    20641 tgcatttaaa agcaatcgaa atcatcggcc attctttgga agtttctgta gatggcgatc
    20701 aaaatgggcg agaaaaaatg gcattaggac agtatattgc gggaatgggc ttctcaaatg
    20761 tcggtttagg actggtacac gggatggctc acccgttaag tgcatggtac aacattcctc
    20821 atggcgtagc gtgtgcagca cttttgccaa ctgtcatgaa atataacaaa gaatatactg
    20881 gagaaaagta ccgtgagatc gctcttgttc tagggattaa aggagcagct gaaatgtctt
    20941 tagaagatgt aagagaagcg gcttgtggtg agatcgatcg gttgagcaaa gcggttggaa
    21001 tcccagaaac catttctgaa ttaggtgtaa aagaagcaga tattccagca attgcagaag
    21061 atgctttgcg agatgtatgc acaccaggaa atccaagaga aacgacagta gaagaaatca
    21121 ttgctttata tcaaagtttg atgtaaaaac gaagcggatc ttcaacatta aattgcctgt
    21181 aaagagaaat ggtagtttat atctggatat ctcttttaaa ttgatggtat ttccgctata
    21241 atttttctta taaagaaata ggagaatatt atatggaaaa taaaaagcct tatggaactg
    21301 tattgatcaa agcctctaaa atactagact atttagcgga aaaccaagat gtctctttgc
    21361 agacgatcgc aaagggtgtg ggaatgacct cttctacagt cttgaaaata ctagatactt
    21421 tgttgatgat cggctacgta aataaaaatt cagagaaaaa ctatcgttta ggtgcaaagc
    21481 ttattcgcta cgcgaataaa aacattgaac aaatcgattt ggtagagttg actttaccgt
    21541 ttttagaaca gctgcagcaa aagatcgatg agactatcca cttaggggta ttggacaaca
    21601 atgagatctt gtacgtgaac aaactagatc caaaacatca aacgatccgc atgtcttcaa
    21661 aaatcggaat cacccgacca ttatacaatt ctgcgatggg caaagccgta ttagcagaat
    21721 tcagtgaaga gcagtacact gattatcttg aaaagcatcc gttgatccct tacacagaat
    21781 atacgatcac caatgcatta cggttgaaaa aggaaatcca aacggtaaaa gaaacccaca
    21841 tcgcatttga cgatgaagaa atcgaacgtg atattttttg tataggagcc tcaatcgtga
    21901 aaaacgaaca aatcattggt gcatttagtg taagtatgcc gaaatatcgt ttaacagatg
    21961 agacaaaaga acaaataatc agtgccctca agcaaacaaa aagcgaaatc gagcaaagaa
    22021 ttcaaaaata atgaaaaaag cgtttgcaat ttttcttttc tgccgtataa tatgggtata
    22081 gatttccaag ttataaaata aaatttctaa ataggaaata ggtggagaag atgaaaaaaa
    22141 ttgatatttt atctcgattg aaaaacgccg gagtgattgc ggtggtacgc ggaaaaagca
    22201 aagaagaagc tttgaatgct tgccacgcaa tcatcaaagg tggtctaact ggtattgagt
    22261 tgacttttac agtccctcaa gcagatcaag taatcaaaga acttttgtca ttctacaaag
    22321 accaaccaga aatagtgatt ggcgcaggca cagtattaga cgctgtcaca gctcgcttgg
    22381 ctatcttagc tggcgcagag tatattgtta gcccttcctt tgatcaagaa acggcagaga
    22441 tgtgcaatct gtatcaaatt ccttacttac caggatgtat gactattacc gagatcaaaa
    22501 cagcgctgaa aagcggggta gatatcgtca aactatttcc tggaagcgct tatggaccaa
    22561 gtatcatttc tgccttcaag gcgccgatgc ctcaagtcaa tatcatgcca actggcggtg
    22621 tgagtctgga caatatgaaa gagtggttcg atgctggtgt cgtaacagtc ggagtaggtg
    22681 ggaacctttt agcacccgca gctacaggag attttgacaa agtaacggaa gtcgcgcaac
    22741 agtatgcagc aaaaatgaaa gaaatcaaga ggtagctgct tatgggaaaa gtagtgacac
    22801 tcggagaaat catgttgcga ttgtccacag agcagggaac ccgtatcgat tcaagtgaac
    22861 gattcgctgc ccattatggc ggaggggaag caaacgtagc aatttcttta gctaattacg
    22921 gacatgaagc gatttttgct acaaaagtac ctgataacgc attgggaaaa gcagtcaaaa
    22981 agcacttgca atgttatgga gtagatacga aacaggtatt atctggtgga tcaagactag
    23041 gtacttatta tatggaaact ggtagtggcg aacgcgccgc ctcagtgatc tatgatcgtg
    23101 ccggatcaag ttttgctgaa atggatcatt tggaatggtc gctagaggag ttattccaag
    23161 gaatagatat atttcatgtt tcaggaatca ccccagcttt gtctaaaaaa tggcaaaaaa
    23221 tgacgaaaca ggtgatagaa gctgcaaaaa aagctggctg cctgatcagc ttcgatatca
    23281 actatcgtgg aaaattatgg acacagcaag aagccagcga agtaatccat cagcttttac
    23341 ctttagtaga tatctgctca gctggaaaaa tggatgctct ttatttgtta ggtatcgaga
    23401 aagcgccaga agcagaagaa caacctctaa tttattatta tcaaaaaatg caggaaaagt
    23461 tcccgaatat tcaggtgttt tattcgacca agcgtaccgt tcattcagca agtgaaaatg
    23521 aattgaaggg gacattgtgg atgaaccatg aatatgtgga atcccaagtc catagaatca
    23581 ccccaatcgt ggatcgagta ggtggcggag atgcttttgc aggtggcgtg ctccatggga
    23641 ttttatccaa tatgtctccg caagaaatca ttgattttgc tacggcagct tctgccttga
    23701 agcatacgat ccatggggac tgcaaccaat ttagtcaaga agaagtcgca caatttttag
    23761 catgcggctc tggaaaaatc attcgataga aggagtagaa gaaaatgcaa gaaatggaaa
    23821 cacgttatac acacagtcca gaagatatcc gtcattattc aacggaacaa ttgagaaaag
    23881 aatttttagt agaaaaggta tttgaaccag ggaaaatcag tttgacttat acgcacaacg
    23941 atcgaatgat ctttggtgga gtgacaccta ctgaaaaaga attagaaatc acattagaca
    24001 aagaactagg tgttgattac ttcttagagc gtcgtgaact aggtgtgatc aatatcggtg
    24061 gaccaggatt catcgagatc gatgggcaaa aagaagaaat gaaaaaacaa gacggatact
    24121 atatcggaaa agaaacacga catgttgtat tttcttctca agatgctgaa aacccagcta
    24181 aattctatat tagttctgtt ccagctcatc ataaatatcc aaatgtaaaa atcagtatcg
    24241 accaagtaaa accaatggag actggtgaag gcctgacact gaatgaacgt aaaatctacc
    24301 aatacatcca tccaaatgta tgcgaaagct gtcaattaca aatgggttat acgattttag
    24361 aaccaggaag cgcttggaat acgatgcctt gtcatacaca tgaacgtcgt atggaagctt
    24421 atgtctactt tgattatgcc aatgaagata cacgtgtgtt ccacatgatg ggcaaaccag
    24481 atgaaacaaa acatttagtt gtagacaatg aacaagccat tatttcgcca agctggtcga
    24541 tccattcagg tgtaggtaca agcaattact cattcatctg ggcaatgtgc ggagaaaata
    24601 tcacctatac agacatggat atggtgcaaa tggatcaatt aaaataagca taagggagag
    24661 aaaatgatgg aatttagtat ggatatgttt cgtttagatg gaaaagtagc attagtcacc
    24721 ggtgctgtct atggtattgg atttgagatt gcacgctctt tagctacagc aggagcaaaa
    24781 atcgtattta ataacttgaa tcaagaatca gttgatgaag gtatagcgca ttataaagaa
    24841 gcaggcatcg atgcaaaagg ttatgtctgc gatgtgaccg atgaagaagc ggttcaagcg
    24901 atggttcaac agatcaaaga agatgtaggt tcagttgata ttctagtcaa caatgcaggg
    24961 atcatcaaac ggacaccgat gatcgaaatg gatgcggcag acttccgcca agtaatcgac
    25021 gtggatttaa atgccccatt catcgtttca aaagcagtta ttccggatat gatcgaaaaa
    25081 ggcggcggta aaatcatcaa tatctgctcc atgatgagtg aattaggacg cgaaacggtc
    25141 agtgcttatg ctgcggcaaa aggcggatta aaaatgctga cgaaaaacat cgcttctgaa
    25201 tacggtcaat acaatatcca atgtaatgga attggaccag gttatattgc tacaccgcaa
    25261 actgctccat tacgcgaaac acaagaaaac ggtgaacgtc atccattcga tcaatttatc
    25321 gttggacgta cgccagcagc acgctggggc gagccaatcg atttggctgg accatctgtc
    25381 ttcttggctt ctagcgcatc tgatttcgtt aacggccatg tcttgtatgt ggacggaggc
    25441 atacttgcct atatcggaaa acaaccttaa aagagcttta gtacactgtt tagtggagag
    25501 gttgtgaaat cagcggattg aacgaatacc gaaggacagc tgattaaaca tcatttattc
    25561 gaaaaaagag gctgggacag aagcatttaa ctccaagaaa taagaaggaa ttcacgaaaa
    25621 ttgcttttca aatttttgtg aatttcagct tatttccgaa ggagttgctt ttacttccgc
    25681 cgtttgtacg tgtttagagc gtgagacaaa agtgttcttt acttttgtcc cacgctcttt
    25741 tctgtgcgtc ttccatactt cactaagtcg atccctcttg cttcgcacca atccttcact
    25801 ggtccggaaa agatcagaga ttgttggtgt agggccgcgg tattcgttgc gccgaccata
    25861 gtataaagca gacgaagctc ttcttgccat tgcttcatca gtataatagt ttcttctacg
    25921 ccgtgattca tcagatgcgt cagtacggtt cctgaagtac ccacggcatt tgcgccgaga
    25981 caaagggctt taaatatgtc ataggcattg cggatacctc cggaggctag gatttccata
    26041 gaagtgtctg cttcatttgc ttcaagcaat gaagagactg tcgattgccc ccagtcagct
    26101 aaataactca gttcccgctt ggagcgacgg gcgttttcga tctgggtgaa gcttgttccg
    26161 cttcgaccgc tgatatcaac tgtatgaact cctaaagcag ctagatcatt gagcgtttct
    26221 cttgtcatgc caaaaccgac ttcttttacg atgaggggga cgtcaatggc tgtttgagtt
    26281 tcttgaataa gtactttcca attggtaaaa tcacggtctc cctcaggcat aaccaactct
    26341 tgaggtgcat tcaaatgaat ctgtaaggca tctgcgtgaa acaatcggat agcttctttg
    26401 gctctttcga cagaagtccc tgcaccgatg ttggcaatga ttttcccgtg aggatattct
    26461 tgtcgcataa tcgtataagt atcggctaaa gaagggactt tcaaggcagc gctgactgaa
    26521 ccagtggcaa tcatcaaatc tgcttctctt gcgacgattg caagatcttg gttgattttt
    26581 tttgtttttt cgcttccgcc agtcatcgca ttgatataaa atgggctgct tagtgtaaac
    26641 ccaactgcct gtgtacttag atcgacatca gaaactgcta tttgcggcaa agggttatgg
    26701 atgatccgta cgaagtcaaa ttcgtttttt tgtttatcat gaaaggcttt agctagtgaa
    26761 acatgttcgt cttttcgatt catcggtttt cctttctttg atcgctatag acatgtaacg
    26821 gcagtggagt gatttctgct ttttcccatg cactcattaa aggaagaatg ccagatttct
    26881 ggtcaacaat tacgattccg caatcgcccc cacctgcacc agaagatttt gcggctcctt
    26941 catactgttc agctaaatta cacaatttgt tcaaagcagg cgtttcgatg acgaccccag
    27001 tgattgcaga taaatcatgc agtaattgtc ggttttttcg aatcatctgt tggatcaacg
    27061 ttacattatt ttctttaaac cctttgatca tttcgttgac acattctgta ctatttttta
    27121 agaaaagctg ataagccacc attttatctt ctctcgaacg gtgaacttga tcgaccaaat
    27181 cagaagtaga ggcagggcta cccgtccaac caatcaataa acgtaaatct tcaggagcaa
    27241 tcaatggctc aatggataga cctggccaat ccagggcaag taactcactg atagaatgct
    27301 gagtttcttg ttcttggagc caaggatggt cgaaggttga gaaagcgatc cagccaccat
    27361 aacagctagc agcgatgtcg ccgcaggaac cattatcttg aactgctaaa ttggctagtg
    27421 ctgcaatctt gaaaatctcc aactgagata aattcaacgc gtaaaaaaca ttcaaggctt
    27481 tgaccgttgc aacggtcacg gcaccgctag aacccaatcc atatttccgg ccatttgaac
    27541 tgtctaactc acttgttact ttcagatcat aaaaggataa aagaatgttt ttttcttgtg
    27601 catacttttc agtcaagcga atagcagcaa ggatataatg aaaaggattt tcccgaatat
    27661 ctaaaactaa ttctccgttg cgtcttgtcc aacgtacagg catcccacta tattgtgcag
    27721 attggatact tccgactttt cgtgcagatt ctacagtgac tgtcacgaat tgatcgactg
    27781 cagcgataac tgctggatgg cctgtttcaa caactgcata ttctccggca atatagagtt
    27841 tgcctggtgc agatacttca atcataaaaa tctcccttta ttcaataatc gcaattcctg
    27901 gaccagcatg tgcagtaatt acttgttctt tgctaaataa tttggtaaat gtttcttgta
    27961 cctcagataa atggctgttt tccactaaaa ctttgacatt agggccagca tccatcgtaa
    28021 agtagcatgg aatgccttgc tttctcaatt gtcgcaccgc atccatcgct tttaagctgt
    28081 caggagacca gtaagtgaat ggaggctggg cagctaaagt cgttccatgc atttttagtc
    28141 cgtttctttc catcgtttct ccgagaagtt ggaaatcttt tgttttgatt gcttgtttca
    28201 attgatatag atccccttca acggaatcta accagccttg ataaaaactg gatgtttcga
    28261 ctgtccgacg catcccattt ctgctggaca cttctttttt ctggtcgttg atcaaaacga
    28321 aaaccattgc taaatcgtct tcgaaagaat cggaagggac tggcttagcg taagaactta
    28381 agtcgtcatg gcctttttcc cattcgacga aaccaccgaa aatacttcgg caagctgaac
    28441 cagacccgcg tcgagcaaat cttgaaagag agagatcatc taatccaagc ttaagagcag
    28501 tattgcaagc gcctgctaaa gcagctagcc cgctggcaga ggaggctaat ccagctgcgg
    28561 taggaacgaa attctgactg attactgaag cttttagtga gaggccggct tctttacgaa
    28621 aaaggtcaag aaactgactg actttttttg ttgctttttc gtcttgcaag gtgccatcta
    28681 gataaaattc atctaccata tagctatcag aaaagatgac ttctgtctct gtataaaatg
    28741 catccaatgt taacgaaagg ctgttgttca ttggaaggat gagttcttca tttttcttac
    28801 cccaatattt gattagagca atgttggtat atgcgcgtgc tttgccttta aacataggta
    28861 tgtactccta atccttgtat ccaagtttca gcagcacccg catcttcaag tgcttgactg
    28921 atttcttggg cttttgtttt tgtttgtgct aatgcaatca tacagccacc gcgtccaccg
    28981 ccagttaatt tggcacccaa tgccccggta tcttttgctg tttggatcaa tagattaaga
    29041 aaatcattgc tgattgtcag cttttccaga agtgattgtg attcatccat tgtctgtgcc
    29101 aacgtttctg gtgaattttc aatgattgct tgttttgctt gcttcgtcaa gtatcctaat
    29161 ttttggatca tttgtccagt ttcatgaggc tgggtttcaa agaggtgagc gacatctttg
    29221 acggcttctc ttgtttgtcc tttgattcct gtatcagcga caatcaaaaa agcatcgatg
    29281 ttcaaagaaa agtagtcgaa aggatgccct tttgtaaaat aaatcggctg caagctgcta
    29341 gtagcggctg catcgattcc actaggatta ccgtgggcga ttttttccga aagctggaca
    29401 ttttctaata gtatttcacg agacaaagga aatgctaagt aatcataaaa agcacgagtg
    29461 actgctgtgg cgactgcagc gcttgatccc attccacgtt cagcaggaat cgtgctttca
    29521 atggtcagtt gcaagttttt ttggatgtca tgctgttttt ttaagtgaat gaataatttt
    29581 ttgatatttt ttaatgcatg aggagcttcg gctaaatttc ctgaatagta ggaagaaacc
    29641 agttgatcgt ccattgcatc cagctcttca aggaatgcgg tgacttttgt tgcatagaaa
    29701 ggaaaggcaa tcgctggttc tccataaaca accgcgtgct cgcccatcaa tatgatcttt
    29761 ccgcttgatt ctccttggcc atagtttgcc ataatctaac tccttctcac gtaaaagtga
    29821 tttttaagca aaaaataaag cgcccaaaac gagttgcgct gcttcacgaa tttttttgtc
    29881 cact
//
LOCUS       DAZUJR010000031        28200 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.031, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000031 DAZUJR010000000
VERSION     DAZUJR010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28200
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.031"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(74..385)
                     /locus_tag="ACG804_001276"
     CDS             complement(74..385)
                     /locus_tag="ACG804_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFS4832219.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPGPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(387..584)
                     /locus_tag="ACG804_001277"
     CDS             complement(387..584)
                     /locus_tag="ACG804_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HFS4832220.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(978..2705)
                     /locus_tag="ACG804_001278"
     CDS             complement(978..2705)
                     /locus_tag="ACG804_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HFS4832221.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2698..3891)
                     /locus_tag="ACG804_001279"
     CDS             complement(2698..3891)
                     /locus_tag="ACG804_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HFS4832222.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4078..4722)
                     /locus_tag="ACG804_001280"
     CDS             complement(4078..4722)
                     /locus_tag="ACG804_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFS4832223.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4816..4950)
                     /locus_tag="ACG804_001281"
     CDS             complement(4816..4950)
                     /locus_tag="ACG804_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HFS4832224.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(4952..7084)
                     /gene="feoB"
                     /locus_tag="ACG804_001282"
     CDS             complement(4952..7084)
                     /gene="feoB"
                     /locus_tag="ACG804_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HFS4832225.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7081..7554)
                     /locus_tag="ACG804_001283"
     CDS             complement(7081..7554)
                     /locus_tag="ACG804_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HFS4832226.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            7955..8179
                     /gene="nrdH"
                     /locus_tag="ACG804_001284"
     CDS             7955..8179
                     /gene="nrdH"
                     /locus_tag="ACG804_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HFS4832227.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8338..10497
                     /gene="nrdE"
                     /locus_tag="ACG804_001285"
     CDS             8338..10497
                     /gene="nrdE"
                     /locus_tag="ACG804_001285"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HFS4832228.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFLSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYAMAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10547..11512
                     /gene="nrdF"
                     /locus_tag="ACG804_001286"
     CDS             10547..11512
                     /gene="nrdF"
                     /locus_tag="ACG804_001286"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HFS4832229.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11601..12740)
                     /locus_tag="ACG804_001287"
     CDS             complement(11601..12740)
                     /locus_tag="ACG804_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFS4832230.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAV
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13049..13762)
                     /locus_tag="ACG804_001288"
     CDS             complement(13049..13762)
                     /locus_tag="ACG804_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HFS4832231.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(14016..14717)
                     /gene="nagB"
                     /locus_tag="ACG804_001289"
     CDS             complement(14016..14717)
                     /gene="nagB"
                     /locus_tag="ACG804_001289"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004342 - glucosamine-6-phosphate
                     deaminase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HFS4832232.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            14951..16483
                     /locus_tag="ACG804_001290"
     CDS             14951..16483
                     /locus_tag="ACG804_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFS4832233.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16674..17876)
                     /locus_tag="ACG804_001291"
     CDS             complement(16674..17876)
                     /locus_tag="ACG804_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4832234.1"
                     /translation="MKSNEKKPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMAALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTVFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQTVVFKG
                     KRNLENKK"
     gene            complement(17958..18647)
                     /locus_tag="ACG804_001292"
     CDS             complement(17958..18647)
                     /locus_tag="ACG804_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFS4832235.1"
                     /translation="MKKKIIRLILISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(18753..19121)
                     /gene="rplL"
                     /locus_tag="ACG804_001293"
     CDS             complement(18753..19121)
                     /gene="rplL"
                     /locus_tag="ACG804_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HFS4832236.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(19174..19677)
                     /gene="rplJ"
                     /locus_tag="ACG804_001294"
     CDS             complement(19174..19677)
                     /gene="rplJ"
                     /locus_tag="ACG804_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HFS4832237.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(19881..20008)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(20087..20776)
                     /gene="rplA"
                     /locus_tag="ACG804_001295"
     CDS             complement(20087..20776)
                     /gene="rplA"
                     /locus_tag="ACG804_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HFS4832238.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(20880..21302)
                     /gene="rplK"
                     /locus_tag="ACG804_001296"
     CDS             complement(20880..21302)
                     /gene="rplK"
                     /locus_tag="ACG804_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HFS4832239.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            21645..22313
                     /gene="sdaAB"
                     /locus_tag="ACG804_001297"
     CDS             21645..22313
                     /gene="sdaAB"
                     /locus_tag="ACG804_001297"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HFS4832240.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            22326..23198
                     /gene="sdaAA"
                     /locus_tag="ACG804_001298"
     CDS             22326..23198
                     /gene="sdaAA"
                     /locus_tag="ACG804_001298"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HFS4832241.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(23289..24389)
                     /locus_tag="ACG804_001299"
                     /pseudo
     CDS             complement(23289..24389)
                     /locus_tag="ACG804_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324221.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
     gene            complement(24481..25368)
                     /locus_tag="ACG804_001300"
     CDS             complement(24481..25368)
                     /locus_tag="ACG804_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFS4832242.1"
                     /translation="MTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEVSDKEKT
                     AESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDGQIQATG
                     DLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSMGGVSAL
                     RYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQDYQQMI
                     GNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTGENASHS
                     MLHENQEVDQLVSRFIWKE"
     gene            complement(25445..25990)
                     /gene="nusG"
                     /locus_tag="ACG804_001301"
     CDS             complement(25445..25990)
                     /gene="nusG"
                     /locus_tag="ACG804_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HFS4832243.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(26091..26261)
                     /gene="secE"
                     /locus_tag="ACG804_001302"
     CDS             complement(26091..26261)
                     /gene="secE"
                     /locus_tag="ACG804_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HFS4832244.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(26285..26437)
                     /gene="rpmG"
                     /locus_tag="ACG804_001303"
     CDS             complement(26285..26437)
                     /gene="rpmG"
                     /locus_tag="ACG804_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFS4832245.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            26599..27243
                     /gene="cbpA"
                     /locus_tag="ACG804_001304"
     CDS             26599..27243
                     /gene="cbpA"
                     /locus_tag="ACG804_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-AMP binding protein CbpA"
                     /protein_id="HFS4832246.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(27299..27802)
                     /locus_tag="ACG804_001305"
     CDS             complement(27299..27802)
                     /locus_tag="ACG804_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HFS4832247.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(27815..27861)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
BASE COUNT         8543 a         5820 c         4974 g         8863 t
ORIGIN      
        1 ttatgtcact gattcaatat acctattttt ctaatcaaaa aattttgaga catatttaat
       61 attataagta tcattaaaat tgagatttat ctccataatc tgctcgatat aaaccattta
      121 ttccagcagt tcttccaatt tcactcaaat ttcttattaa ttcctcttga tattcagtga
      181 atcttatttt attagtataa gcagtaaaat atagataatt caccaatcta tttattaaag
      241 gaccgggatc taattcatat ttttgttttt ctaattttaa atataccttt tgtaaaacct
      301 caagaatatc agaatattta ggatctttac ttatagatat atcattatat aattcatgaa
      361 caatttgctt agcatttttt ttcattttag cacttccctg gaattgctcc acctaaaaaa
      421 ccacctatag acattcctgc aatacaagta gttgccttgg cccaatcgac cgtacattta
      481 tttttagtgc aatacactcc atttccataa tattttccac tatgagtggt acccccatag
      541 ataagttgtg tctctttaat agacaaaatt tttaaatgtt tcataatcta atcaccccta
      601 aattaatgtt tttagactat tattctaaca ttcattaaat ttcaaaaaac aattccttct
      661 tgaaacgtag caaaataatt cctgaataag aatttaatca cttttaagta tataaactat
      721 gtatattctt taatattttt tgagaatgca cttcgtacat aataaacttt aatcacatta
      781 gtctttcata cctacgatcg atctctttga ctcgcaccca taaattcata atagtttgtc
      841 ggcgtctttg gacgtttcga agatgagcta cgcattctct ttttttatag acaaaaaaga
      901 tagagacgaa catggagctt ccaaatttgg atatttgatc caattttgga agctccattt
      961 atttcgtgtc tgtcttttta ttttttccag ctttcgacta attcttggtt ctctttgatc
     1021 cagtcttttg ctgcttgctg tggatctttt ccattgttga tttccaacat aactttttcc
     1081 atatcttttt ctgaccaatg gaaattgtct aatactttgt aagcttctgg ctggtcttct
     1141 ttcaatcctt ttcgaaccat cgtatggatc tgctcttcgc ttcccattcc gttttcagga
     1201 tcttctaagt atttcagatc atatttggca aacatccaat gaggtgtcca tcctgtaact
     1261 acaattggtt cgtgtttttt gatcgcttga cctagtgcaa cggtcattgc tcctgaagaa
     1321 gatgtctcta ctttccagtc tttcaagttg tcatattttt ggatcgtgtt ttcagcagcc
     1381 gtaactacac cagctcctgg ctcgattcct atgattttct tacctgcctg atcggttaac
     1441 tcatcgatcg aatttacatc catgtaggct ggcactgcta aaccaacttt tgctcctgtc
     1501 aaattggcac ctaggtcttc gacttgatct ttatattgtg catattgtga accatgagtt
     1561 ttaggtagcc aagctgaaac catggcatct gactcgccat ttgaaacaga tttccacatg
     1621 attgaattat ctaatggcgt catcgttaca tcatagccca tttgtttcaa tacttcaccg
     1681 actacatttg ttgaagcaac ttctgtatcc cattcaacat aagataagtt gatacgtttt
     1741 gtttctttgg cagatgaaaa actccctata ccaatcgcac ctaagatcac tactactaca
     1801 gcaccaatga tcagtccttg acgtttttta cttttctgtg ttgttgctcc tgcagctttt
     1861 ttattgtttg gctggttcaa atgctgtgta aaacggtcaa tgatgattgc taagataact
     1921 aatgcaaccc cgttgacaaa tccattcccg acttgtgctc tttgcaatgc tgataatacg
     1981 ccgcgtccta agccgggtgc accgatcata gaggcaataa cgaccattga aagtgacagc
     2041 attgttgttt gattgatccc tgccatgatc gtacttttag ctaaaggcaa ttctagtttg
     2101 aatagttttt gacgacttgt gctcccgaat gaatcagaag cttctactaa ttctttagga
     2161 acttgtcgaa tccctaaatt cgtaaaacga acggttggtg gcagagcaaa gatgactgag
     2221 gcaaataccc ctggaaccat cccgataccg aaaaatgcaa ctgctggaat caaataaacg
     2281 aatcctggca ttgtctgcat aaagtcaagg atcggtttga taatactttg ggctttactg
     2341 ctttttgcca tcaagatccc taatggtacc ccaatgatga tcgagatcac actagataaa
     2401 agaacaagtg tgacagtatt catcaaatca ttccatagac cttggttata aataaaccat
     2461 agaccgatta atgtgaacaa cgtaagtcct ggacgtttct tagaaataaa gaaagctgct
     2521 accgtcaata acaagataaa caaaggagct ggaatcacta acagtaaatt tgtaatcccc
     2581 gacatcactg cctgtccaat cgtttgtaaa aatgaaaata ggccagaaaa agttgtcgta
     2641 aaccattctg tgatattttc tacccagttt gccactggta attgatagtt caatagatta
     2701 ttcatgttca ctcacctcgc ttgtttctgc taatgcttca atcacactac ctcggatgac
     2761 gacacctttt aattttccat cctctacaac tgcaagtgga gtcggtgagt cataaataat
     2821 attgaaaata tcacttacca ccatgtcttt cccaatcacc gtcacatttt catctaggaa
     2881 gtcgatcaat ggacgttttt gcttcctagc ttctaacgct tgatctgcag tgatgatccc
     2941 tttcaggtgt ctctttctgt caacagccat cagcatgctg acttcttcat tacgcatcct
     3001 tgtcaatgca acgtttggtc catcagattc gatattcgtc gtcaatgcag gtaccatgat
     3061 gttttgagcc gtaagcactt tggaacgatc gacttcttcc acaaattcac gtacataatc
     3121 atttgctgga ttggtcaata tttcttcacc tgttccgatc tgcatgattt cgccgtcttt
     3181 catcaaggcg attctgtccc caatccgtaa agcttcattc aaatcatggg taatgaaaat
     3241 aatcgttttt tgaacattgg cttgcaggtc cagtaattcg tcttgcattt ctcgccggat
     3301 cagcggatca agagccgaga acgcttcgtc catcagcaag atctcaggat catttgctaa
     3361 agctctggct aggccaaccc gttgttgcat cccaccagat aactgactag gatattggtc
     3421 tttaaatgaa agcaaactag aattttctaa tgctttttct gctttttctt gtcgttcttc
     3481 tttaggtaca ccacggactt ctaacccgta ttctgtattt tccaagatcg ttcgatgtgg
     3541 aaacagaccg aagttttgga aaaccatatt gattttatga cgacggactt ctcgcaattc
     3601 ttctttgctt aacttcgata catcttctcc atcaatatag atactgcccg aagttggctc
     3661 aatcagacga ttcaatagac ggatcaatgt ggatttccca ctcccggaaa gccccatgat
     3721 cacgaagatt tctccttctt ttacgtcaaa attcacgtca tacacaccaa ccgttgcacc
     3781 ggttttcttt aaaatctccg ttttcggctg gtgatcattc atcatatcta aagcggcttg
     3841 tgtcttttta ccaaatatct ttgttaaatg ttttacttct acttttacca aacaaattct
     3901 ccttttttat gtaaattcat ttttctttct gaaaaaagtg accacactat gttaacatca
     3961 tgtagtcact ttgtcaaaaa tgaaagaaat ttgcttgtcc aaactgaaaa aaacttggct
     4021 aaatctttgt aaataaaagg tttagccaag ttaatatttt tttaatattt cacacaatca
     4081 ttctgcaagc tgatgctccg ggtaaaaaaa gtttgtcata cgctgtagtg tatattcatt
     4141 tccaataaaa tgaacgatgt cccctgccgt aaatttagca taggggccag gtgaaacaag
     4201 cagttcttca ttatgagaaa ttgcgataac tgtggcgcca gtcgcctgcc agatattcaa
     4261 ctcgctaatt gaacggtcca gatgcattgc tttttctgat aaagataatt caaacggaag
     4321 taaaggattc atcttatgta ttcgcttcgt ttgattgacc agctgatcca ataattgaga
     4381 aaaatgattc agctcatctt gttgcttctc cacacttgcc atgatttctg cttttgtatc
     4441 ttggatggat tgtacatctt gatattgcaa taggaaatct tttgcttttt ccttcgaagc
     4501 aacaaatgcc ccacttccat gccgtacttc catgattcca agatctacca gcacattgat
     4561 agccttgcgg gtagtctcag gagaagcatt gtacgtactg gcaagtgttg agcgggcatg
     4621 gatcttctca cccactttat atcggttttc aacgatacgt tcggctaaat caacagcaat
     4681 ctgctggtag cgcgggcgga cgattttttt ctttccagac attttctttc ctctttcttt
     4741 ttttactttc cctcatctta ctatgctcta gcaaaataag caaaaaaggg gagaatagcc
     4801 tcttgcaacg actgatcatc gcttgatctg ttcctttttt actgggcaag ctgtttgaca
     4861 gtcatcacaa ttcttaccgg attttaaacg agtatagaca attgcgcctg cacttccaaa
     4921 gattaacaca cttaataaga atgtcgccat cctattcctc tccttctaat gacaatatag
     4981 tataaaactg gttcttggat tttggctgac ggaacaaaac ataaacgagt cctatcatca
     5041 gtaaaatagc aagatacgtc cctaacgcta cctgtccacc ctccaataag tgtcccaact
     5101 gataaatcac aaaactaact aaataagcta aaccgcattg atagcctatg gcgatccaag
     5161 tccatttctt ggcattcatt tcccgatgga tagccccaat tgccgcaaaa caaggcgcac
     5221 aaagtaaatt gaaggctaac aatgaataag ctgctgcggg agtatatgtg tgttgtagca
     5281 cttgccagat ttctctgcca ttttcggata cttccgcatg accaaacaaa ataccaaatg
     5341 tgccaataat attttcttta gcgaccaatc ctgtaatcgc tgcgactgtt ccttgccagt
     5401 ttccccaacc aagcggctga aaaacaactg ccaggattcg cccgaaaaag gctaagatac
     5461 tttggtcttc agaaacaggt tgagcataaa aattataaga agagctgaac cagatcacga
     5521 tactagaaac aaagataatc gttcctgctt ttttaacaaa agacttgctg cggtcatagg
     5581 tttgtcttag gaccgctgac cattgaggaa aatgatatgc gggcaattcc atgataaaag
     5641 gagctgtatc tccagcaaac aaacgtgttt ttttcaagct gattccagag aaaataattg
     5701 cagtcatacc aagaaaatag gcagaaggag ctacccaaga ttgatgagga aaaaaggccc
     5761 ctgctactaa ggcaataatc ggcaactttg cagaacaagg catgaaggtt gtgaccatga
     5821 tcgtcaaacg acgatcttgc tcgttttcaa tcgtgcgact ggccatgacg cctggcactc
     5881 cacatcctgt agcaatcagc ataggaatga aggattttcc tgaaagaccg aatttcctga
     5941 aaagtcgatc catgacaaaa gcgatcctcg ccatatatcc gcagtcttcc agaaagctca
     6001 agcataaaaa caatataatc aattgcggta gaaatcctaa cactgctccc acgcctgcga
     6061 tgatgccgtt caagatcagc tcctgcatcc atcccgctac ttgccattca gctaacaatc
     6121 tgccaacatg ttctggtaac catgtaccaa acaatgtgtc attgatccaa tctgtcccca
     6181 ttgttcctac tgtttgaata gccagataat agatcagcca catcacaaat gcgaagatcg
     6241 gcaaggctaa ccaacgattc gttgcaatct gatcgatttt gtcactcatc gataattgga
     6301 aagaatcatt tgacacaaca cagagtgtac atagttgggt aataaattca taacgttcat
     6361 tgaccagaat cgtctcacta tcgtcgtcca atagtttctc tgttaactgg atcagttgct
     6421 cgatctcttt ttgctgagaa actgctatct cgtaatcctc tcttaccttc tgatctcgtt
     6481 caaaatattt cattgcatac cagcgtttct tgccgctttg ttctcctagt acatcttcaa
     6541 tttcatgtaa agctgcttct aaacgtggat catatgtaca gggaacagga atagaaggcc
     6601 gcttttttgc agactcctga atcttttcga ttagtttttc gattccttgc tttttcaata
     6661 cgctgattgg taaaactggt acaccaagac cataggaaag cttttctaga ttgatttttt
     6721 ttccttcttt tttgatgaca tccatcatat tcagaccaat gatcatagga atgtctaaat
     6781 ccaataactg cgtagttaaa taaagatttc gttctaaatt ggtagcatca ataatgttga
     6841 tgatcagttc aggctgttcc tgaaccaaat aatctcttgc aatcacttct tctggtgtat
     6901 aaggagacaa agaatagatg ccgggtaggt cctgaatatg aatgttcgga ttttttttca
     6961 acgatccttc ttttttttct actgttacgc ccggccaatt ccctacatat tgattcgaac
     7021 cagtcaagag attgaacaag ctagttttcc cgctgtttgg atttccgact aacgcgatat
     7081 tcattctttt tcctcccttt gtatcaagat tagttcggcc tctgactttc gtaacgtcag
     7141 ttcataccct cgcactgtca gttcgattgg atctcccaga ggggctagtt ttcggataac
     7201 tatttttaca tttcgcgtca atcccatatc cattaaccgt cgcttcactg cgccttgtcc
     7261 gtggattgct acgacgatcc cagtctctcc tgcttttaat tgatcaagag aagtccagct
     7321 ttcagaggaa gcagtctttt tattgacaaa gatttgacct agtatttccc gacttactgc
     7381 cactcgatga ctttttacca gtaaaatggc attgttgcct gataaattga cgacgacgat
     7441 tttacttccg gcaacgatcc cgatattttg caaatggcgt tttgtttttt cttctgtttc
     7501 gattcgttcg acttgataaa cgaaattctg ctttgcctgc gctaaggtct gcatattgat
     7561 tcctctcttg tgaaataaat catgtattaa aatcattcat tatatgttct aattttctta
     7621 cgtgttacgc aaataaatga gaatcattct cacatagaat actctcggta attgagaatg
     7681 tcaattatac ttgtgatatt atgagcgaat ctttagtatt gatagataaa aatgagaaaa
     7741 aaatatttct tcatagtttt ccacaatttt ttctctatta aatttgctat tttcccacac
     7801 gatacttgtt ttcagctctt ttttcaaaaa cacaaaactt agtattccac agtttccaca
     7861 acacaatatg tagtgtttgt tgtttgactt ttttactaag agttttatac tatctattat
     7921 agataataag aatgtgttag aggaggcact caccatgaac gtaaaaatct tttctaaaaa
     7981 taattgtatg caatgtaaga tggtcaaacg gtttttaaca gaaaatcaaa ttgcttttga
     8041 agaagtcaat atcgatgaac agcctgaagc agtagactgg ttgaaagcac aaggattcca
     8101 aagtgttcct gtcattactt ctgatgcaga aacagttatc ggattccgtc ctgatcagtt
     8161 gcgtaaactt gccagctaac atgactaaaa gaatcaaaac gtgatacatg gatttgaagg
     8221 gcttgagaca gcaccagttt ttgtcgcaaa cttccaaatc cttttttaaa gcttaaaaac
     8281 aatgcaatga tttgcaatca agcatcatca aatacgaaat gaaggttggg cgtacgtatg
     8341 agtcttaaaa atttacaaga tgtcagttat ttcaagctga ataatgaaat caatcggcca
     8401 gtcaatggtc aaatcccttt gaataaggat aaagaagctt tagttgcctt ttttgaggaa
     8461 aatgtcaaac caaatacgat gacttttcta tctattatgg aaaaaatcaa ttacttgatc
     8521 gatcaagaat atatagaagc agaattcatt caattgtatt caccatcatt tattgaaaag
     8581 ctatatcaat ttttggacga gcaacatttt tctttcaaat cttttatggc tgcttacaaa
     8641 ttttattctc aatatgcgtt gaaaaccaac gacggttccg cttatctgga aacttatgaa
     8701 gatcgagtag ccttcaatgc gctttacttt gcgaacgggg atgaagaatt agcacttgct
     8761 cttgcagacg aaatgatcca tcaacgatat cagccagcta caccttcttt cttgaatgct
     8821 ggacgtaaac gtcggggcga attggtgtct tgtttcttga ctcaagtcac tgacgatatg
     8881 aactctatcg ggcgctcaat caactctgct ttgcaattgt cccgtattgg tggcggcgta
     8941 gggattactt tatcaaatct tcgtgaagcc ggcgctccta tcaaaggata tgagggtgct
     9001 gcaagtggtg tcgttccagt catgaaatta ttcgaagata gtttcagcta ttctaatcaa
     9061 ttaggtcagc gtcaaggagc tggcgtggtt tatttgaacg ttttccatcc agacattatt
     9121 gctttccttt cagcaaaaaa agaaaatgca gatgaaaaga ttcgcgtaaa aactctttct
     9181 cttggcgtga tcgtacctga taaattttat gaattgacac gtaaaaacga agatatgtat
     9241 ttatttagtc catatagtgt cgaaaaagaa tatggtgtcc cattctctta tgtaaatatt
     9301 acagctgagt atgatcatct agttgcaaat ccaaacattc gcaaacaaaa aatcaaagcg
     9361 cgtgatcttg aaaatgaaat ctcaaaatta caacaagaat ctggctatcc ttacgtaatc
     9421 aatattgata cagcgaaccg cgagaatcca atcgatggca agatcatcat gagtaattta
     9481 tgttcagaga ttttacaagt tcaaacgcct tctgtgatta acggcaaaca ggaatatgaa
     9541 gtattaggaa cggatatctc atgtaactta ggctcgacaa atatcgtgaa tttgatgcaa
     9601 agccctaact ttggtcaatc tgtgcgtacg atgactcgtg cattgacatt tattacagat
     9661 gcatctgata tcgatgtcgt accaccgatc caaaacggaa ataagctgaa tcatacgatt
     9721 ggattaggtg ccatgggctt acacacttat cttgcaaaag aacaaatgga atatggctca
     9781 gaggattcat tagactttac aaatatttac ttcatgctgt tgaattattg gacacttgtt
     9841 gaaagcaaca atatcgctcg tgaaagaaaa caagttttcc ataattttga aaaatcagct
     9901 tatgctgacg gcacttattt cgaaaaatac gtaactggag aattccagcc aaaatcagaa
     9961 aaagtcaaag cattgtttga aggcattttt atcccaactg ctgaagattg gaatgctttg
    10021 aaacaagcag taatgaaaga tggactgtat catcaaaatc gcttggcagt agcaccaaat
    10081 ggctcaattt catatatcaa cgatacgagt gcaagtattc atcctatcac tcgcatgatc
    10141 gaagaacgcc aagagaagaa aatcggtaaa atttattacc cagcgcctta tctatccaat
    10201 gagacgattc cgtattacac ttctgcttat gatatggaca tgcgtaaagt aatcgatgtt
    10261 tatgcaatgg cacaacaaca cgtcgatcaa ggcatgagtt tgactttatt catgcgttct
    10321 gaaatcccag aaggcattta tgaatggaag acaacaacga agcaaacgac acgtgatttg
    10381 aatattttaa gacattacgc tttccacaaa ggaatcaaat ccatttatta cgtacgtacc
    10441 tttactgatg atgcagaaga aatcggaagc aatcaatgtg aaagctgcgt gatctaatat
    10501 catagataga ttcgcttatt catattttaa ttaaaggagc attctcatgt cagaaacata
    10561 ttatgaagca ataaactgga atgaaattga agatatcatt gataaatcca cttgggagaa
    10621 gctgacagag caattttggc tagatacacg tatcccactt tcaaatgacc tagatgattg
    10681 gcgtacattg tctcaattgg aaaaagatac agtaggacat gtatttggcg gtttgacact
    10741 gctagatact gtccaatctg aaagtggcat ggatcagttg cgtaaagatg tccgcactcc
    10801 ccatgaagaa gccgttttga acaatattca attcatggaa tccgttcatg ccaaaagtta
    10861 ttcttctatt tttagtacac tgaatacgaa aaaagaaatc gaagaaattt ttgactggac
    10921 aaatacgaat ccttatctgc aaaaaaaagc tgagcgtatc aatgaaatct acaaacacgg
    10981 tacaccgcta gaaaagaaaa ttgccagcgt ctttttagaa acattcttgt tctattcagg
    11041 tttttatact cctctttatt atttaggaaa caacaaattg gctaacgtag cagagatcat
    11101 caaactaatc atccgagatg aatctgtaca tggaacctac atcggttaca aattccaatt
    11161 aggattcaac gagttacctg aagcagaaca agaaacgtta aaagactgga tgtacaatct
    11221 tctttatgag ctttacgaaa acgaagaacg ttatacagaa gaattatacg atccaatcgg
    11281 ctggacagaa gaagtcaaga cattcctacg ctataatgcc aacaaagcat tgatgaacct
    11341 agggatggat ccactctttc cagatactgc caatgatgtc aacccaatcg taatgaacgg
    11401 gatttcaaca ggcacaagca accatgactt cttctcacaa gtcggaaacg gctatttgtt
    11461 aggtcatgta gaagcgatga aagacgacga ttatttgatt ggattggaat aaggatttat
    11521 tttaattcaa aaatttttcg aaaaataaaa agagtttagc gtacagatat tttaaatgta
    11581 cactgaactc ttttttatgc ttattcactt gtttcttcca gcacttttgg actgtctaac
    11641 ttttccgaaa catgttccat tcttctcaat aaatagattt tccggatatt taatattatc
    11701 gtcttaatca ctgcatagac aggtatgcaa atcagcatgc ctaatattcc tgcgacactt
    11761 cctgctccaa tcaataccaa gatgatcgtc aaaggatgga tattcattga tttcccaaat
    11821 aacaacggct tgatcaaatt tccatctaat tgttggatca ctaaaatcga caacgccata
    11881 tacaaagctt gaaatggaga gataaacaaa ccgacaatga ttgctggtac cgctccaata
    11941 aaagggccga catacgggat aatattcgtg attccgcaaa tgaccgcaag caacaagcta
    12001 taaggctgat cgaatattct cattgccaaa aagctcatta caccaataat caaagcatct
    12061 aagatcgtac tgctgatata ggcagataat gtttcgttta attcttttac cgtttggcgt
    12121 aactctttac gaatcgcttt cggaaagaag tgagacaacg catcaataaa tttgtgccca
    12181 tccttgaaca taaatagcaa aataaatgga acggtaaata acaaaataaa aaattgcatc
    12241 ataaatgaaa tgatttttga gacacttgca gataaactga ctaatatgat attgaacaaa
    12301 ttactaagag ataaatttgc tgatgctaat tgttcttcca aattgaaatt tttaaactct
    12361 tcccgctgcg ccaattcatt taaccatttg cttgtttcat ctgcatacat tggcaagctc
    12421 tgggtcaatt gaattgtctg ttccattaac tgaggcacta cattcatgac agttaaaaca
    12481 actaaaatga ttacgaccaa aaacgtcaat aaaaaaccga acactctcgg gatccgatgc
    12541 ttttcgagaa aaacaacgat tggatcgaac atataataga taaaaccagc aacaagcaat
    12601 ggtaaaaaaa ctgccgaaag cattttcaat attggactaa aaatattcgg catttgtaaa
    12661 ataaagtaca cgccgatgat cgtgagtact agctccactg tccagaaaaa taattttgat
    12721 tgtttaaaac gtgattgcat acatctcctc caaggtcctt tgatacttct attctatcat
    12781 ttaacaaaga gttacgcgct gagattttca tttgcttaaa aaaaacaaaa aaaataaaca
    12841 tattttaatg agtagacgag tacttaaaca aaaacacggt ttggagtagt gacaaaaatt
    12901 atactgcagt ccctttttcc aaataaacgg tgttcaaaag cttgcatctt cgtaataagc
    12961 ccagccaaac gaaaaatata aggaactatt tttatttggc tgggcttatt acttgatgta
    13021 ggacatctat tttacaacct cagatcattt attgcgcaat actgactaaa tgcaactttg
    13081 tgatattttt gtgtacggac aactcctcga tcacatcggc ataagtgagc ccttttggaa
    13141 gatcaatcgt atagatattt ttgtacactc ggtagtcatc aacgaatttt acgtcaaaat
    13201 tcacatcttc gattacgata tttttctctt caaaataatc ggtaagaaaa tctttggttt
    13261 cttttctatg gataaattgg atttctaact ttttagtcgt aggtacatgg atcacgcgtt
    13321 tcactactgt gagtgcaata gcaatcccga taaaactgat gatcgcaatg gaatagtaac
    13381 ccatgccgat ggcgatccct aatccagcaa ttgcccataa agaagcggca gtcgtaagtc
    13441 ccgtcaccga ttgtttcgtg acgatgatcg ttcccgcgcc taagaaaccg acaccactca
    13501 ccacttgagc aatcagcctt gcttcatctg aacgaatcgt tccagcaagc tgtggatact
    13561 ctaaagcatc tcttaatgca ccactagcga tctcaacttg gatcaatgca atgatacatg
    13621 ctcccataca aactaaaata tgcgtacgca tacctgctgg acgattttta tattgtcgtt
    13681 caaaaccgat tgctccgcca aatagcatag cgatccctaa acgtaaaata atctctggaa
    13741 ttgtcaatac catatcattc atctaaacac cctccagtcc aatatatcat gtctgaaagg
    13801 agcagacaaa aaaagtgcaa tttttacctc ttacgaaaaa aggactgtga caaaattttt
    13861 gtcatagtcc tttttatgaa taaacggtgt tcaatcagct gaccctcggt attactcaac
    13921 aaacggcaaa atatggggag ctatttttcc tttgtcttct ctaatactca ggtcaaaacg
    13981 ctgatttcac aacctcttta gcctactatt gaaaattaca acttacttgc tgcttcttca
    14041 tcgatgatca caacaacatt gtcgtgattt tgcaatacac ttgctggcaa atgattcgtt
    14101 acaggtcctt caatcatccc tttgattgca tcagctttgc tttcgccaaa tgccatcaag
    14161 acgatttctt tacttttcat aattgaaccg attcccattg aaacagcttt tgttggtaca
    14221 tcttctgctt tatcgaagaa tcgtttgttt gcattgattg ttgattctgt taagtcaact
    14281 actgaagtcg ttccgtcaaa tgaagcacca ggttcattga aaccgatatg tccattttgc
    14341 ccgattccta agatttggat atcgattgga tgtgcatcga tgatttgatc atactttttg
    14401 catgctgctt ccagatcttc tgcttttcca tctggtacaa acgtttcttt gaatggtttt
    14461 ttatcaaata attggacatc catgaaatga cggtagcttt gttcatctga accgcctagt
    14521 ccaacgtact catctaagtt tacagaagtc atttcactga aatccaaatc gcttgaagtc
    14581 atttctttat ataaagtaac tggtgtgctt cctgttgcca atcctaatac ttttgcacct
    14641 ttgttcatac cttctttgat gatttcaaat gctttttttc cgccttcttc agcgtttttt
    14701 acacgaatga tttccatagt gattgctcct ttatattttg gtatagccca attatagcat
    14761 tctttttttc tttttacaat aattagtata gaccaaattg catttttttc attttcttga
    14821 caataaatag gaatccgtgt taggtttcat aagatggttc aatcaaacaa tccatgttgc
    14881 atgaaaacca agcaagtgat tcactgtgga cgctttatgt ctgcagtttt tttatgaaaa
    14941 aggagttatt atgagtatac tgacattaaa caacattacc cagcaatttg gcgacaaaat
    15001 cctctatgaa ggtgtcgatc tgcaattaaa tgctggcgaa catcttgggc tgattggaca
    15061 aaacggagcc ggtaaaagta cattgattaa aatcatcact ggtgagatct taccagatga
    15121 cggacagatc cattggcaaa aaaatattca caaaggttac ctcgatcaat atgtggaagt
    15181 cgatgaaaca ttaacaatcg aagaatttct aaaaactgcg tacgcaaaag aatacgaaaa
    15241 ggaagaaaaa attgcttttc tttaccaaac atatagcgag accttcgatg attccttgct
    15301 ggaaaaagct gggaaactcc aaacggaatt agaccaagga gtgttttatc aaatcgacac
    15361 cttagttgct gagatgagca gcgggttggg gatcgatgtc ttaggtttag attcactgtt
    15421 gaaaaatcta agtggtggac aacgttcaaa ggtgatttta gcaaaactac ttttagaaaa
    15481 cccagatgtt ctgatcttag atgaaccaac caatcactta gatgatcagc atatccaatg
    15541 gctgacgcag tttcttcagg attttgacgg tgcgtatatc gtgatttccc atgaccaaga
    15601 atttcttgat cagatcacca cccatatcgc agacatcgag tttggaaaga ttactaagta
    15661 tactggccat ctaaaacaag cattgaaaca aaaggaacaa aatcgcgaaa gctatttgcg
    15721 ccaatatcat gctcaacaaa aacaaatcga aaagaccgaa gcttatattc gaaaatacaa
    15781 agccggttcc cgatcaacga tggcaaaaag ccgacaaaaa caattagata aaatcgaacg
    15841 gctgacgcct ccagcttcag caagtaaagc tgtctttgat tttccattct cgcctattgt
    15901 cacgacatta gcagtggaaa caactgattt agtcatcgga tatgatcgac cgctacttgc
    15961 acccatcaat ttgaccatcc gctttggtga aaatattgcc attcgaggct tcaacgggat
    16021 tggaaaatct actttattaa aaacactgat cggtgagatt gaaaaaataa gtggcgattt
    16081 ccacttccca gataacacaa aaatcaatta cttttcacaa gatctgtact gggaaaatcc
    16141 attagaaaca ccactacaat atttaagcag tcaatttcca aaagcgacta tcaaagaatt
    16201 acgtcgccaa ctagctaaag cagggttagt taatcaatta gcaagtgaac ctctcactac
    16261 attaagtggt ggggaacaaa ctaaggtgaa acttgcacag ttgacaatga accaaggtaa
    16321 tttactgatt ctcgatgaac cgacgaacca tatcgatcaa gaaacgaaag aaagcttaca
    16381 agacgggata cagaaatttc caggaacagt aatcatcgtc tctcatgaac aagaatttta
    16441 tcaagatctt gtgcaacgag tcattgagat tgaaccaaaa taaacgtttg attgaatagt
    16501 tgaaaaaaag gagctgtgac aaaagttttg tcacaactcc ttcttctgaa taaatggtgg
    16561 ccaattagct gaccttcggt attagctcaa aaaacggcaa aatatgagga gctattttta
    16621 tttggctatt cttattactt gatgcagaac agcttttcac aacctctttt cgtctatttt
    16681 ttattttcga gatttctctt tcctttaaaa acaactgttt gaaagaagaa cgcacatcct
    16741 tgaaaaacaa gcccgctaac cgttacacct aaccagccat actgctgcca cattgtcgtc
    16801 cctagcaatg aaccagccgc acctccaata aagtacataa acataaatac agtattattt
    16861 cggttgcttg ctgcttcacc tagcccttgt actcgtgttt gattggcgac ttgaccaaat
    16921 tgattcccga cgtctaataa aataatagct aaaagcaaaa tggccaaatg gcttccgcca
    16981 accaataaag caataaagct tattgtttgc ataacaagtc ccatatacac gatttttctt
    17041 tcagaataag aatctgccag tcgtcccacg ataggtgcag caactgctcc agacaaacca
    17101 aaaatcgcta atatccctgc ttcgaatgtt ccccaattgt aggcgggact gctgatataa
    17161 aaaatcaacg tagaccaaaa gatcgaaaat gttccaaaca tgaaaaatcc actgactgcc
    17221 gcttctctta atagacgttg agaagcaact aaatgcggca aacttttaag tgaatcaagg
    17281 tatgaaacag ctgtactact ttgctggaca gaacgcggca ttttccagta aagcagaagt
    17341 gtaagaattc cgactgcaca taaagcaaat aaatagatca tccgccaaga aaaaagactg
    17401 gcaacaatac cagataccgt ccgagaaagc aaaatcccca cgagtaaacc gctaagcaat
    17461 gtacccatga ccttccctct tgcttttggt cccgctagta ccgcaccgta aggaatgatg
    17521 atttgcggca cgatcgaaag taatcctatt aaaaaagaag cgcatgcaaa taacgtaaac
    17581 gaaggcgcaa aaaaagcggc caacagagag acggcagata acgctgccat tcgaatgatc
    17641 aattttggac gatccaccac gtcccctaaa ggaactaaaa acagtaaccc taacgcatag
    17701 cctaattggg tcaacatcgt caatatcccg actgcacttg tgctaacaga taaactagct
    17761 gctacttttg ttccaatcgg ctggatgtaa tacatattgg caacaacaac gccacaagtg
    17821 attgataata gtaaaataag cgaagttgtt aaaggttttt tttcattact cttcattgat
    17881 ttcccccatt tcctatctta gtttacaact tatggaaaag attggaaata gaaaaataca
    17941 actattcgcc acacttatta tttgtgcttt tgttttcctt gttttttctt gcgatcttta
    18001 taaatgaaga caactaaccc tactagcaca gtaacacttg caaccaacgt gactgcagtt
    18061 ttgttatatc cgtgaaacag agcttctcca ccacacgcat acaacacaga cgaagggatg
    18121 actccaatca cgatcgacaa tatgatttgc tgtagaggca atttcatcgc atctgcagca
    18181 aaattgacca tagaagatgg aataaccggt atcatatagc ctaacattac acctattttt
    18241 ggatgtttca tttgtcggat tgcttgcacc caatgattcg tttcggtttt cttatctaaa
    18301 aattttaagc gatgcataag gaaaattgca gtgatgttac caagagcatt acccaaaatg
    18361 ttgatgatcg cacctgtcag tggtccaaag ctcaaaccag caatgactcc aactactgaa
    18421 gtaggaatac ctggaacagc acacatcacc gctgtcaata cgatcaagag tatcgatgca
    18481 aaagtcccat gcgaacgaat atgtgcgagt agctctgcct tactcgctct cggatttaaa
    18541 aataattgga tgtctgtctg atattctaaa tacaaccgat agcccactac cagtatcaga
    18601 atgattccca acgagatcaa tatcaatcgg attattttct ttttcatatt tcctcctgaa
    18661 aaaaatctat attcattaaa taatagttta acataaaaac aaaaaagcac cgaaatccaa
    18721 cataggatct cagtgctttt aaatagtaaa aattatttaa cagttacaga tgcgccaact
    18781 tcttcaagtt tagctttcaa ttcttcagct tcttctttag atacgccttc tttaactggt
    18841 gcaggagcgc catcaactac agctttagct tctttcaagc ctaaaccagt tgcttcacga
    18901 actgctttga taactttaac tttttggtct ccagctgcag ttaattctac agtgaattct
    18961 gtttgttctt cagcagcagc agcgccacca gcagcagcta cagctacagg agcagcagca
    19021 gatacgccaa attcttcttc aatagcttta actaggtcgt taagttctag gatagttgct
    19081 tcttttaact cagcaacgat gttttcaatg ttcaatgcca ttataatttc ctccgtttaa
    19141 ttgttctttt ttatttaatg ctttatgcgg caattaagct gcatctccat cttctttgtc
    19201 tgccactgct ttgacagcgt aagccacgtt gcggactggc gcttgtagta cagatagcaa
    19261 catagataga agtccttcgc gatttggcaa ttttgccaat gctgtgattt cttccaatga
    19321 agagacttta ccttcgatga taccgccttt gatttctaat gcttttgctt ctttagcaaa
    19381 ttcgtccatg attttcgctg gtgcgactac atcttcgtta ctgaatgcaa cagctgtagg
    19441 tccagtgaat acttcgtcca tgccttcaag gccagctttt ttagctgcac gtgaaagaat
    19501 agaatttttg ataactttca tttctacgtt agcatcacga agttgtttac gtaaacgtgt
    19561 tacttcatca actgttaatc cgcggtagtc aacgactact actgatgcag ctgctgtaaa
    19621 tttttcgctt acttcatcaa cgattgctgc tttttttgcg ataattgctt cactcatttt
    19681 tgagtttcac ctcctgaatt ttgatggaag agttttttgc actgaaaagg caagtcactt
    19741 ttatagttac tttgctcaac cagtattatt catcacctat tcacttcgtt catagtgatt
    19801 ctactcgctt tgctcgaaag gaaactcctt tcgctttgct caaccagtat tgttcatcat
    19861 ctcttcactt cgttcatagt gattcacaat aaaaaactct atgccaccgc agacatagag
    19921 ggactattga atatattcaa taaacgtcct cggtaggaaa ttaaggcttg atgccaccta
    19981 ctgtcttcgg tacaagttaa ttattaacct caactagctt agcatgctaa actagttgag
    20041 tcaagaatta tttttcagtt ggatcaatca acattctaat atttaattag aaagaagctt
    20101 ggtcaacatg gataccaggt ccaaatgttg ttgtgatcgt tacatttttc atgtattgac
    20161 ctttagctgc tgatggttta gcttttagca atacatcatg gattgctgca aagttttcaa
    20221 ctaatttttc atcgtcaaat gaaacttttc cgattggtac atggatattt ccagctttgt
    20281 ccacacggta agttacttta ccagctttca cttcgtttac tgcttttgtt acgtccattg
    20341 taactgtacc agttttaggg tttggcatta agccttttgg tcctaatact cgtcctagac
    20401 gacctacagt agccatcata tcaggtgttg caacaactac atcaaagtca aaccatccgt
    20461 tttggatttt ttgaaccatg tcgtcgtcac ctacgaaatc tgcaccagct gcttcagctt
    20521 cttttgcttt gtctccttta gcaaaaacta aaacagtttg tgttttacca gttccgtttg
    20581 gtaatacaac agcaccacgg atttgttggt ctgctttttt agggtctacg ttcaaacggt
    20641 atgcaacttc aactgttgca tcaaattttg caatgtttgt ttcttttgct aaagctactg
    20701 cttcggcaac aggataaact ttacttgaat caactttttt taatgcatct tgcatttttt
    20761 tgctcttttt agccattttg gttcctcctt gattgtggtt ataacggttg tacctcccac
    20821 gtgttctata tctttcaata tagagccaac tgagaagctg ctgtcttagg gtgtatagat
    20881 tattctacag tgatccccat gcttcgtgca gttccttcaa ccatgcgcat tgctgcttca
    20941 acgttagctg cgtttaggtc ttccattttt aattcagcga tttctcttac ttgatcgcta
    21001 gaaactttcg caactttatt tttgtttggt tcgcctgaac ctttttcgat tttagctgct
    21061 tttttcaata gaacagcagc tggcggtgtt tttgtaacga atgtgaatga acggtcttcg
    21121 tatacagaaa taacaaccgg aatgatcaaa cctgcttgat cagctgtacg agcgttgaat
    21181 tcttttgtga atcccatgat attgataccc gcttgaccta gtgcaggacc tactggtgga
    21241 gctggagttg ctttacctgc aggaatttgc aatttaacga ttttttctac tttctttgcc
    21301 acgagacata cctccttaag tccgtgatgt ggttaattgg agatgcatat ttctcctccc
    21361 acgttttatc tgatctgaaa aaatccagac aaataatgtg caaaacaatg cacactggta
    21421 cagtatagca aatttatttg ttttttcaag atttttttct gctattttta cattttgctt
    21481 gaataaacgc taaatttatt ctaaaaaaac aacaattttt cgttctcatt tcttctttta
    21541 tgttacactt gcgctagcat ggttcaacag atgaaagcaa acaataacac ggttttttag
    21601 acccttgtac aaagattcct acataacaaa atgaggtgga gaaaatgaaa gatttaaggt
    21661 atagaagtgt ctttgatatt attggacctg tgatgattgg tccaagtagc tctcacactg
    21721 ccggagctgc tagaatcggg aaaatcatac gtagtatatt tggcgaacag cctgattctg
    21781 tagatattta tctatatgaa tcatttgcaa aaacctatcg ggggcacgga acagatattg
    21841 cattagttgg cggcctgtta gggatggaac ccgatgatga acgtttagct gattctttga
    21901 aattggcata tgaagccggt atggaagtct tgtttgttcc taagagtgaa aaagccgaac
    21961 atccaaactc tgtaaagatg cttctaaaaa aaggaacacg aaagctttca gtcactggca
    22021 tttcgatcgg cggtggcaat atccagattt ctgaattgaa tggattcaaa atttctttaa
    22081 gcatgggtac tcctaccttg atcgttgtcc accaagatgt tccaggtatg attgctaaag
    22141 tgactagtat actttctgag accaatacga atatcggcac tatgacagtg acacgggaat
    22201 caaaaggtga aaatgccatt atgataattg aagtagatga tcctcaagta gaagaaacgg
    22261 taaaaagact caaacagctg ccaaatatcg acagcgtaaa ttatttcgat taaggagcta
    22321 aaaaaatgtt tttatcgatt gaagaattag tagatcaagc aaaagcttat ccaagtgtag
    22381 cagaattgat gattgcagtt gaaatggaaa tgagtggccg ttcccgtagt cacatcatcg
    22441 agatcatgga aaaaaacctc tcagtaatgg aacaatcaat caacgaggga aaagaaggtg
    22501 ttacctccgt cacaggaatt accggtggtg atgcaaaaaa attagatgat tatttaaatg
    22561 aggcagactt tttaagtgga gaaacaatct taaaagctgt acgcaatgct gtagctgtta
    22621 atgaagtcaa tgcaaaaatg gggttgattt gtgctacacc gactgccgga agcgcgggtg
    22681 ttgttcctgg tgtgctgatg gctgtccgag atcggcttga tttgacacat gaacagcaat
    22741 tggaattctt atttaccgct ggcgctttcg ggttagtcat cgcaaacaac gcttctatca
    22801 gtggtgcaga agggggatgt caagcagaag ttggttctgc aagtgcaatg gcagcagcag
    22861 ctttggtttg tgcaaaaaat gggactcctc atcaagcagc acaagcagta gccattacat
    22921 tgaaaaatat gatgggactg atttgcgatc ccgttgcagg cttagttgaa gtcccgtgtg
    22981 tcaaacgtaa tgctttaggc tcttctcaag cttttatctc tgctgatatg gcattagcgg
    23041 gtatcgaaag tgtcattccg ccggatgaag tcgttgctgc aatgtaccaa gtcggacgtc
    23101 aaatgccgtc gattttcaaa gaaacagcag aaggtggctt agctgttacg ccaactgcta
    23161 aacgacttgc ggaagagatt ttaaataaga gggcgtgata aagctcctta atttcgagta
    23221 ttaagagatt agttatcttc ataacaaaaa acgaagagag gactaattgc ccttctcttc
    23281 gttttttatt aatccatcaa tttcgtattt tttacttcat cgatcgtttt tgttcctgca
    23341 agttgcatcg tgatcgacaa ttctttgttc aggtgttcaa aaacagatgt tactccttct
    23401 gccccaccta gattcaaccc ataaatcact ggtcggccaa tcgcaactaa gtcagcacca
    23461 cttgccagag ctttgaagac atgctctcct cgacggacac cagagtcgaa aatcactggt
    23521 acacgtttgt tgactacttc ggcaattttt ggcaatactt caaaggacgc aggacctcca
    23581 tctagttgac gtccaccatg attggatacc cagataccat ctgcccctgc agagatagcg
    23641 attactgcat cttctggcga ttgtattcct tttacgataa ctggaagatg ggtgatttct
    23701 ttgattgttt tgatgtcatc tggtgtcaag ccttgttttg cagctgcata aatttctgcg
    23761 attccttttc cttcgccatt accacttgca ctttgttcgc tatacgcagc taagttaggc
    23821 attggtaatg gaaattggaa ttgattgatg acgtcttctt cacggtaacc accgagcgtt
    23881 gaatctgccg ttaaaatgat agctttagcc cctgcttcta ctgctttgtt caaaatgaac
    23941 tcattgaatc tgtcgtcttt actcatatat aattggaaaa actgcggtgc gcctggcgct
    24001 gcatcggctg cgtctttgat tgtcgtattt gcataagtgc tgatggaaaa gattgatcca
    24061 gcagcagcta ctcctttagc tgtatcagct tccccttttt catgtgccaa tccttgggcc
    24121 gctgatggcg cttggataat cggtgtatct aattcaattc cgaaaacaga tgtatgcaaa
    24181 tcggctgagt cgattccgcg taatatccgt ggcatgattt tctttgtatt aaaagaagtc
    24241 gtattttctt tcatcgtcca ctcatcttca gaaccaccgc gaatatagcc aaaagctcct
    24301 gcttccatgc gctcttttac acgaccttct agttaggcaa tgtttacaat atcgattgga
    24361 tgttcttcat tacttgtatg ataagtcata gtagatcctt ctttcatctt cttgattaca
    24421 tataaatcat actaaactta caaaaagtaa gcaaacattt actctcagat acttttatcg
    24481 ctattctttc caaataaatc gacttacaag ctgatctact tcttggtttt catgaagcat
    24541 actatgagag gcattttcac ctgtcactac tttttcctct atttcatttc cgcgttgctt
    24601 caacaacgca tagaccgcta atgcactgtt taacggtact gttccatcac tcaagtctgt
    24661 ttcatctagt tgaccagcaa tcaagaaaaa tcgagtggtt ataggaatat taccgatcat
    24721 ttgctggtaa tcttgatagc ggttagaaac gacagcaggc ccctttgcta actcatctgt
    24781 cagagactgc gcactatcat cgacaaaatc attaaaaggc gcgccaattg ctgttaatgt
    24841 ctgaacttgt ggcaatgacg tatcctgtcc atacgttcct aaatagcgta gtgcactaac
    24901 tcctcccatg gaatgcccca ctatgttgac tttatctatg ccgtagtttt ctttcagata
    24961 caaaagacaa gttttgatcc attctgcttg attccactcg ttatttttat tatcttcaaa
    25021 caatacttgg accatcggat tgtctgcttt tccagacaaa tctcctgttg cttgtatttg
    25081 tccatctgtt cctactgtta aaaccaattc ttttactgct tgctgatttt tttccaaacg
    25141 ccgcaacatc cctttaaagg aattttctgt cccgctgtag ccgtggaaaa aaagtgttgg
    25201 aatagtggtt ttttctatca ctttactgga ttctgccgtt ttttctttat cagaaacttc
    25261 agtagtattt atcttcgtcg tctggcaacc acttaacgca aacaaactga taaggactaa
    25321 agctgctgca gttgcacgtt tgcataaatt tttgattggt tctgtcatac acctcttcct
    25381 ttccatatag aaaaaagaaa gacttgaaag gccaatcata tgatcgacat ttcaagtctc
    25441 tttattaatc gattttatct acttgatcga aatcaagttc tgtactggtt tcacgtccaa
    25501 acatatcgat gttgactttc aatttttctt tttctccgtc aacttctgtt acttgtcctt
    25561 ctaatccagc aaatgcgcct tcgatgattt tcacgacttc gccaacttct acttctagat
    25621 cattttgtcg caggctcata ccgatagaac gcaagatatg attgacttct tctggaagta
    25681 atggtgctgg tttgcttccg gctccgtgtg aaccaacgaa tcctgtcaca ccaggtgtgt
    25741 tgcggacaac ataccatgaa gcgtctgtca tgatcatttc aacaagtacg tatcctggga
    25801 atgttttatg aacgatttct ttttctttcc catttttgac ttcagtttct ttttcttcag
    25861 gaacaacgac acggaaaata aagtcggcca ttttcatact ttgcgcacga gattcgatat
    25921 ttgcttttac tttgttttca tatcctgaat atgtatgcaa gacataccag tttttttcaa
    25981 aagattccat tgaaggctcc tcatttcatt gtaaaataaa aaaacctcag tacacccgaa
    26041 gtttttcttt cgcttcatta tagcactaaa agtacgttgt ggctagcgag ttattttaaa
    26101 atccagccaa ataagctttg gatggctgta tccattacgt aaaacatcaa tccgaaaata
    26161 atagaagttt cgatgactac taacgtatct ttacggagtt gttttctgct tggccaagtt
    26221 acttgtttga tttcatcttt tacgcttttt agaaatttca tgagacaacc tcccttgcta
    26281 ctgtttattt cgtttcttta tgtaatgtat attgattaca atatttacaa aacttattga
    26341 tttccaaacg ttcgccgctt tttccttcac tgactgattt tgtgtagttg cgagacccac
    26401 aaacggaaca agcgagtgct gcttttttct ttgccattta cttctgcccc cttgctgaga
    26461 atcagactta tacttcataa cagtatcacg taacttttta cttgtcaatt tgtgaaataa
    26521 actatctatt gttttggata aaattatgat atgattaatt tgaaattaag ctaaaatgag
    26581 acaattggag gtatagcgat gctattaaaa acacttgtat ataagaaaaa agatctgaca
    26641 accgttacag agactagtac attagaagaa gcattaaaaa ttttagaaac ttccggatac
    26701 cgttgtgtgc cgatcttaga ttcttcaggt aatattttcc gtggaaacat ttacaaaatg
    26761 catatctatc gtcataaagc aaatggcggt gatatgacgc ttcctgtcac tcatcttttg
    26821 aaaaacgcta caaagttcat ttacctggat acttctttct tcaaagtatt ctttacgatc
    26881 aaagagcttc cttatattgc tgtccttgac agtgaaaatc atttttatgg tattttgaca
    26941 catagtacgt tgcttaatat gctctctcaa tcttggagcg tagaacaagg aagctatgta
    27001 ctgacaattg cttccacagg aaagcaagga gatttggctg ctattgcaaa aatcatttca
    27061 aaacacagca gcattgccag ctgtattact cttgatatcg aaaaagacga atacattcga
    27121 cgtacattga tcacgctacc ggctaacact gaagcgaaag tatgtgaaac gatcgtcaac
    27181 cacttagaga aaaagaatta taaagtggta gaaattgaaa atttgcaaaa ccaagaagca
    27241 taatcaaaaa gcgaaaaaag aaaacagcta atctgctttc ttttttcgct ttttataatt
    27301 agacacgctt ttcaaaatca agcgcgcgat ctaaataata catcaatggt gctgaaacag
    27361 ccatgacgat aaactcactt aatgcaagcg tgccataggt tgtccaaaat gcttggccac
    27421 ctgttggaac taacatataa gcaatcagtc ccatgctgat ggtaaagaag atcgtgttca
    27481 atactaaacg catctttaca tttttcactt tgttttgcaa taaagctgtc aggcctaaag
    27541 aaagcaatgt ttggccgcca ccaaaaacca catccatgat accaaaacca aagaaggcat
    27601 tatagacgat gaccccgcct aaaactcccc aaagcaattt acggttaaag acaactaaat
    27661 gattcaaact ttctgaaata cgaaactgga tcggccctga ggatacaggc gcaactaaaa
    27721 tagttaacgc tagataaaga gccatgatga tgccatttac aacgattacg gataaccgtt
    27781 gtctgctttt cgttttttgc attttctctc ctcttttctc ctagtttttt taacgcggga
    27841 tggttgatga accgcggtta tgtgaaacaa acaataatta taacagactt ttcatttatt
    27901 tcaatccgtc ttatctgctt ttaaaaaagc aaaagcttaa acaatgtaaa cgtttgctaa
    27961 aaatcgtggg atatggtata aagtaagtgt aaggggtcat aagaattccc agtaaagcag
    28021 acgaagtagg atctgcaaga acagaattgt tgtgaaactt aaataaataa aaaaggatgt
    28081 gggaatttga gcaacctctt actagagaac ggtctagcaa gcagctgaag atctaagtgg
    28141 acatgccgaa ccttggaact tctccttacg taagtaatgg atcatgcgct tgctaggctt
//
LOCUS       DAZUJR010000032        27680 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.032, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000032 DAZUJR010000000
VERSION     DAZUJR010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27680
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.032"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            109..1587
                     /locus_tag="ACG804_001306"
     CDS             109..1587
                     /locus_tag="ACG804_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4832248.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            1864..3923
                     /locus_tag="ACG804_001307"
                     /pseudo
     CDS             1864..3923
                     /locus_tag="ACG804_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
     gene            4006..4575
                     /locus_tag="ACG804_001308"
     CDS             4006..4575
                     /locus_tag="ACG804_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4832249.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(4750..5556)
                     /locus_tag="ACG804_001309"
     CDS             complement(4750..5556)
                     /locus_tag="ACG804_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832250.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            5694..7208
                     /locus_tag="ACG804_001310"
     CDS             5694..7208
                     /locus_tag="ACG804_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HFS4832251.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            complement(7611..8594)
                     /locus_tag="ACG804_001311"
     CDS             complement(7611..8594)
                     /locus_tag="ACG804_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HFS4832252.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(8599..9246)
                     /locus_tag="ACG804_001312"
     CDS             complement(8599..9246)
                     /locus_tag="ACG804_001312"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding oxidoreductase"
                     /protein_id="HFS4832253.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            complement(9331..9963)
                     /locus_tag="ACG804_001313"
     CDS             complement(9331..9963)
                     /locus_tag="ACG804_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFS4832254.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            complement(9979..10530)
                     /gene="coaC"
                     /locus_tag="ACG804_001314"
     CDS             complement(9979..10530)
                     /gene="coaC"
                     /locus_tag="ACG804_001314"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HFS4832255.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            complement(10527..11264)
                     /locus_tag="ACG804_001315"
     CDS             complement(10527..11264)
                     /locus_tag="ACG804_001315"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HFS4832256.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            complement(11261..12250)
                     /locus_tag="ACG804_001316"
     CDS             complement(11261..12250)
                     /locus_tag="ACG804_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HFS4832257.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIITFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            12508..13050
                     /locus_tag="ACG804_001317"
     CDS             12508..13050
                     /locus_tag="ACG804_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFS4832258.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            13067..14152
                     /locus_tag="ACG804_001318"
     CDS             13067..14152
                     /locus_tag="ACG804_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4832259.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            14164..14970
                     /locus_tag="ACG804_001319"
     CDS             14164..14970
                     /locus_tag="ACG804_001319"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4832260.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            14971..15798
                     /locus_tag="ACG804_001320"
     CDS             14971..15798
                     /locus_tag="ACG804_001320"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4832261.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            15795..16868
                     /locus_tag="ACG804_001321"
     CDS             15795..16868
                     /locus_tag="ACG804_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFS4832262.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            17296..19992
                     /locus_tag="ACG804_001322"
     CDS             17296..19992
                     /locus_tag="ACG804_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFS4832263.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            20057..20557
                     /locus_tag="ACG804_001323"
     CDS             20057..20557
                     /locus_tag="ACG804_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFS4832264.1"
                     /translation="MIKPMFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLS
                     SIQLLTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITK
                     TFLEKEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVN
                     EEEDFF"
     gene            20569..21063
                     /locus_tag="ACG804_001324"
     CDS             20569..21063
                     /locus_tag="ACG804_001324"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFS4832265.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            21084..21893
                     /locus_tag="ACG804_001325"
     CDS             21084..21893
                     /locus_tag="ACG804_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFS4832266.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            21890..22711
                     /locus_tag="ACG804_001326"
     CDS             21890..22711
                     /locus_tag="ACG804_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFS4832267.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            22762..24861
                     /locus_tag="ACG804_001327"
     CDS             22762..24861
                     /locus_tag="ACG804_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HFS4832268.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            24858..25976
                     /locus_tag="ACG804_001328"
     CDS             24858..25976
                     /locus_tag="ACG804_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 172 protein"
                     /protein_id="HFS4832269.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            26015..26893
                     /locus_tag="ACG804_001329"
     CDS             26015..26893
                     /locus_tag="ACG804_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFS4832270.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            27039..27236
                     /locus_tag="ACG804_001330"
     CDS             27039..27236
                     /locus_tag="ACG804_001330"
                     /inference="COORDINATES: protein motif:HMM:NF016526.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HFS4832271.1"
                     /translation="MLLRFLFSFCCALYTLRIFTGGVHLNSNILCYFMSVVIVIVAYQ
                     CMFIFRNVDFIILGLMFEFFW"
     gene            27220..27450
                     /locus_tag="ACG804_001331"
     CDS             27220..27450
                     /locus_tag="ACG804_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832272.1"
                     /translation="MNFFGDRFFQPYKINRNSIIESCDYKKIARKKKKVSIHFKYFIP
                     ISIAKKVEILYLPLTLASLANVVSILIDNKLR"
BASE COUNT         8841 a         4726 c         5772 g         8341 t
ORIGIN      
        1 ctgatgaaaa aacaagcata atccatcata aaatcagtat aggtgaaaag atgaactttc
       61 atctgcatat caagtaattg gtatgaggca ttttttgagg tgtaggatat gaagttggat
      121 taccttatag aagaggaaga tagagaaaaa ctgctgctag ctagatattt agaatttgag
      181 aaaaagaatt atgtagtgct gcctaagtta tatgaaacat taggtttgtc taaatttaaa
      241 acaagaaatt atatcataga attaaataaa gaatttactg aattcaaaac aaagccagag
      301 atccaaattt cagaagaagc agagatccat gtcgaacgtc tgaatttgac ggatatcaaa
      361 aatttaagaa gaatctactt tcaacgatca aaaattgctc gactgttaac ggagatcgtg
      421 gattcaaaag taacgatcga aaaatttgca gagaatcatt ttttaagcat atcaagagcc
      481 tatgtaaaaa gaagagaatt agtctctttt cttgaacagc atcaaataaa gttaaagaaa
      541 aacatattag ttggggaaga aataaacata cggaacgtat tatttggggt atatttcggg
      601 gtctttaatg gtttttctat gccatttaga gaaagcgtca tgaatgaagc aaagagtatc
      661 gtgcaatatt ttgaatatct gttcaattta aaactgtctg caacaaaacg aatcaaattc
      721 aatttgctaa ccactattag tttgttgagg gcctatggga atcaaccaat cggaaaacgt
      781 ttcttttcag atgaatactt taagagctca gaaggaatga agatcatcaa ggatttatca
      841 catatttctt ttcttcatat ccctaaagag cagatcattg atgagatttc ttatatcatg
      901 ttgtttttga tcacggaaga agaatttgaa ttagatggcg catttggact tgcggaagct
      961 cattttcatg atatccacat gattagtcaa aaaatgtcag tggaattgat tgatcaatta
     1021 ccattttcga ttgaaatctc tgaagaagaa agactatata tacgaaaaga acttcgtatg
     1081 ggtatgatgc atgtcaatcg aaaaaattgg atattcgact ttgagatgac tagctttacg
     1141 tctaaaaagc agctacagtt tttcttcgag acgtatccaa tattcagtac agcaatccaa
     1201 aaggtcatac aagagaataa acgctatttc ttgggaaaag atgaacgttt catgattcgc
     1261 ttattttatg attatctctt tttattggtc ggtatttgtc cggtatcata ttttgaagca
     1321 ccgattcatg tctgtattga tttttcgcaa ggatctgctt ataccgatta cattatttct
     1381 caagtgaaag gatttaaaaa ttacaatatt gtgattgaga gtcgaatcac ttctcgtacg
     1441 aatatttatt tatctgattg tttacttgaa aaatttaata aagaacagat aatttggaaa
     1501 aatccaccga ctccagatga ctgggaatat tttggaaata ccatcatcag agaaaaaaat
     1561 agacatttaa ctgaaaaaat cagctagtat ttatggatgg cagctttgtc tcacatattt
     1621 attagctgat ttatgttttt ttcaaagaaa aggtaactag atataactag atataactag
     1681 atatattact taacaaaatt aaaaagtaca taagttatta ttccgatttt cttgaaacaa
     1741 taaaaaatca aaaaaaatac tctcctaata gtccatcttc ttttgatttt atttatataa
     1801 tgaaatcatc ttatgaaaat tactacttca tgtttagaca agagtaggga ggactaagaa
     1861 taaatgtgtt caaaaagacg ttcaaaacaa ctaaataaac acgcttgtcg tttagataag
     1921 gaacggtcgt gttctgaaaa acactacgtt aagtttatga tgcgcacgat gctgatcagt
     1981 ttatctgtag gtgtctatat gcatgtaccc gttcaggcaa cgacacaaac catcaaggtc
     2041 gtacgtacct ctgtttctga gaccactgat tcccctatca ctattactca tactttcact
     2101 gatgcaaatg gaaaacagct acttcctgca ttgacttcct ataataaagt cagttatcct
     2161 ccaacgataa accactactg gttaattcct aacaaaacat tatggacatc ggaaaccgga
     2221 agcagtgtgc cgctttctat cttttccgat atgactgatc ctacaaaagg tgatcagtta
     2281 aaacagatca ctgatatttt gaatcatgct ttgacagata taaaggacgg tggaagcgca
     2341 caagtttctt atgtatatga aaaagattat tcacagtttg aaagaaagaa aatcgatgtt
     2401 ctggcaggga caaaagtttc gatatctgat ctggtagaaa ggctgaagaa cgcagatgga
     2461 acacaaggag atatgtccaa agtaatttca aacaatggga atatcgtgga tacgactaat
     2521 acaggaacat ctactatttc cttgtcctat tttgatccaa ttgctttaaa aacaatgact
     2581 gcatctgctg tgatccatgt tcgtgctgat caaacagcta tcaaaggaaa agatcttcac
     2641 ttaagaacag gagagagtta cgcccctaaa gatcttgttg aatatgtaac aaaaagcgat
     2701 ggaacttcag gaaataaaga agaaatcaaa atgaacggga cagtagatac tacaactccg
     2761 ggagaatatc ccgttgtatt aacttatata gactcgaaaa catcaaatgt ggcagaaaca
     2821 acagctgtag tttatgtaga agcatctgct gcttcatcga ctgtcatcac tcattttata
     2881 gatagtcaaa caaataaaga acttcaagca gaaacacata tgagtagtgt aaatcgtatt
     2941 cctgatttgc gcctacctgc tgaattttct gatcgagtgc caaatataga tttatcgact
     3001 tatgaacaaa atgggaaagt cacttctatt tctgattgga tgcaagcaaa cggattagac
     3061 agaaaaagtc actggtcgga gatccttgaa gtacttcact cagaactgat gaataatagg
     3121 aagcaatcag gaggggaaat tacctttact tatgtttata taccagacaa tcgttcatta
     3181 gaaggtcatg atcttattgt tcatccaaac gaaaaaataa acaaagaaga gttgatccaa
     3241 tcagcaacaa attccttagg taaacccgta ccgttaaagg atgtatcggt tacaatcaat
     3301 gaagtaccat tggaggatgg ttatttgacc aaacaaacag gtgattttac gattatgtat
     3361 agttatcatg acccgtattc actccaagaa ctccatgctc agtcactatt acatgtttta
     3421 ccattaaaca aacagataga tcaaaaagaa caaaaaagac aagaagaaag cttgtcagaa
     3481 aaaaacaaca aatggctcat gcagtttctc caacagggaa agtaaaacaa acaagaagcc
     3541 tagagttagc aagaatatct agaaaaatct cagaatctaa taaaacgata aggcaagaag
     3601 ctcatttggc cccacaagtt tctggattgg aaaatgaaat tttagagcct aaaataaaac
     3661 aacaatcaga aaaagaattt gttgctaaac agtcggaaga tcagaaggaa tcagatgacc
     3721 agaaggaaac gaagaaaaaa cgcttgtcaa ctattgattc caccgatgag catctgcagc
     3781 cgcaagtacc acttcctagt ccgggaacac ccgcacctgg tggaggtatt ccttcttctg
     3841 ctttaggaga tttcatgcga ggtatggcag gaacatgggt atacgctaat cgaaatgaat
     3901 ttgacgcaga tgactggttc tgatttatat ctctatctgt tatagtcaaa taagtagctg
     3961 agtcatatgt tatttggcat aatggagacg aggagggata gaaaaatgtt agataaaacg
     4021 ttaccttacg cagaaatctg gatgacaaga ccacttcaac aaaatgttcc aatcacgcct
     4081 ttagcggaag gttttgaatt tcgattttat caaaaagaag atgaatctgc ttgggcggag
     4141 attgagactt ccgttgggga atttcaaacg acagatgaag cacttgagta ttttcaacaa
     4201 aactttgctc cttatcctga agaacttgaa agaaggatgt tttttgtaga gacaaaaaaa
     4261 ggagaaaaag tagcaacctg taccgcttgg cgaaaaaaat caagagagca agtgtatccg
     4321 gtttttcatt ggttagcagt gaaaccagat taccaaggaa aagggctcgc aaaagcattg
     4381 actgccagag tcttgcaaga atttcctacc ctccatacgg acggaccaat ctatcttcac
     4441 acacagacat ggagccatca ggcgattgct ctttataaaa aaatgggttt tacttttatt
     4501 gctgaaaatc tagacggcac acctaatcca gattatgaaa aagttatgca ggttttaagt
     4561 aaattagata aataacgaaa tggtgaaata agtcctcagt attgggataa aaaacgaaat
     4621 agtcattcct catatcttac ttttttgagt taatactatc ggataactaa tggcatgcca
     4681 tacattcaaa aaagaagggg cagtgacaaa agtattgtca ctgccccttc tcttgttttt
     4741 tagcatgttt tatcgtttga tttttttagg aataaaattc ttgatgaacg taaatttttg
     4801 gtaatcgttt cgactataga ggtaaccaaa tacactgaaa acaactgctc caataaaatt
     4861 aacaaataaa tccttcatag tatccatgat tcccacgtct aagtaaccat tttggatgat
     4921 tgttttatct gttttaccat ctgcattttg actttcaatg attgtccgag tgatatctgg
     4981 aacatgatag acagtgtttc cgtctttact taactccaca ctattgattt gctggatgat
     5041 cgtatctttt tgcatatcga attgcagtaa tttatctgct gaaaattcca caaactccca
     5101 cataacacca actgtcatcg aaaaacagaa ggaaacaact gctagtaata aaggagtcaa
     5161 gttcatggtt tttgtatttt tattgagcaa ataaacaagg gaaaagccga cacccccagc
     5221 taaaaatccg ctgaatgcat gtagaaaagt atcccacatt gaaaaatagc cataaaaatc
     5281 acttaactct cctaaaactg ttgaactaaa aataaaagat aacaaaatga tttctagcat
     5341 atttggaatc tgtatcttta atatcttttc cagaaaataa gggatttcaa ataaaattaa
     5401 tgtcagtaat aaaagcattg tatttcccca gtgttggttc cagacctgat ccactagcat
     5461 aataacgacg atgatacgta ataaaatata gattccgttt gtgattctac ctgcagtttt
     5521 tgtactgttc gtaaaaaagg ttttcaaatg attcataaaa taactccttc atgtatatcc
     5581 ttaattatac taagaagcgt gtgtttacca aagctatatg acttaaagaa aaacagagtt
     5641 gatattgtga aaaaaatcac ttaatatagt ataaggagaa aagggggata caaatgaaaa
     5701 aattagttgc tggtttatta acagccgttg cacttcttgc tatgagcgca tgcggcgcag
     5761 atcagaaaaa tacagcgcag acaagttcta gtacgaagga atctgccgaa gtatcatcag
     5821 gcgcttctga acaagtatat acagatccaa aagaaatgaa agaatcttat gatgtcgtga
     5881 ttattggagc tggtggtgca gggatggcag cagctatcga agcaaaagat gctgggttga
     5941 atccagtaat tttggaaaag atgcctgttg ccggaggaaa cacatctaaa tcatcaagcg
     6001 gtatgaatgc ttcagaaaca aaatttcaaa aagaagaagg aatcaaagac tcgaatgatg
     6061 ccttctatga agaaacgcta aaaggtggtg gaggaacgaa tgataaagaa atgcttcgat
     6121 actttgtcga tcactctgct gatgcggtcg attggctaga tcaaaacggt atcaaactgg
     6181 acaacttaac gatcactgga gggatgagtg aaaagaggac acatcgtccg tctgatggct
     6241 cggctattgg tggatactta gtggaggggt tattgaataa cgtccatgag cgggaaatcc
     6301 ctatttttgt caacgcagat gtgacagaca ttaagaaaaa tggggaaacg gtcaatgaag
     6361 tgactgtaca tgttcaagga gaagaaccaa aagaggtcac cggaaaagca atcgtagtta
     6421 ccacaggcgg ttttggtgcc agcaaagaat ttattgaaaa atatcgtccc gatttagctg
     6481 attatattac gacaaatcaa gaaggatcaa ctggagatgg tatcaccatg attgaaaaat
     6541 taggtggaca aaccgttgat atggataaaa tacaaattca tccaactgtg cagcaggatg
     6601 agggggtctt gattggtgag gttgttcgcg gagaaggagc aatcttggtc gatcaagagg
     6661 ggaaaagatt tgtcaatgaa atggatacaa gggataaagt atctgcagca attacagcat
     6721 tgcctgaaaa atcagcttat ttgatttttg accaaggcgt gcgtgatcgt gccacagcta
     6781 ttgaatttta tgaccaaaaa ggatatgtca caactggaaa gacaatggaa gaattagcag
     6841 aaaaaatcga tttaccaaaa gaaacactag caaaaacagt tgatggatgg aatacggatg
     6901 ttgcggagaa aaaagatgct caattcaacc gtgccacagc catggaacat gacttatcgt
     6961 ctccgaatta ttatgcgatc aaaatcgcac caggaatcca ttacacgatg ggcggtgtga
     7021 aaatcaatac gaacactgaa gtattagata aagaaaacca gccaattagg gggttatatg
     7081 ctgctggtga agtcacaggt ggcttacatg gaaacaaccg gatcggtgga aattcagttg
     7141 cggagatcat tatttttggg cgacaagcgg gcatacaagc agctcgattt gcttcggaaa
     7201 atgaatgaaa tagaacgtaa ataaaaagag gttgtgaaat cagcgttttg agctaatacc
     7261 gagggtcagc tgattgaaca ctgtttagtg aagaggttgt gaaaaagctg ccctgcatca
     7321 agtaataaga acagccaagt aaaaacagct tcttatgttt ttaacttggt tggacttatt
     7381 accgcagatg caagcttttg aacaccgttt attcggaaaa agagcgtggg acaaaagtaa
     7441 agaacacttt tgtctcacgc tctaaacacg tataaacggc ggaagcagaa gaaattcctt
     7501 cggaaataag ctgaaattca caaaaatttg aaaagcaatt ttcgtgaatt tcttcttatt
     7561 tcttggagtt aaacgcttct gtcccagcct cttttttgat cagcatgatt ttattcagtt
     7621 atcttcaaaa tgatttttcc gatgtttttg tttgcttcca tatattcatg cgcttgtttg
     7681 actgcgctga attggaatgt acggtcaatg attggccgaa tcttgccatt ttctagaaaa
     7741 ggcccagctt tttgcataaa agtttgtgcg agctctgctt tatactgatc acttctaggt
     7801 gtcaataatg taccaagcag ttggacacgt ttcccaatca atacaccaag gtctatctca
     7861 ggcacgatgg tcccacctag cataccaatc aagacccaac gtccatcaac ggctatagaa
     7921 gctaaattct tttcccagta agaagcgccg atgaaatcca aaataacatc gactccccga
     7981 ccttcagtga tttttcgtac ctcttcttga aagtcttgtt ttttatagtt gatcaattca
     8041 tctgcaccaa gttctttaca aaaggcgagt ttttcttctg atcctgcagt aacgatgatt
     8101 ttcgcgtgag aaagctgtct agctaattgg atcgctgctg ttcccacacc acttgctcct
     8161 gcatggatca agacagtttc gccttcttgt aattttccaa gccagtaaag tgtttgataa
     8221 gcagtcaaaa aaacttctga gattccagca gcagaaacat agtctagcgt atcagggaga
     8281 aggattgcac gatcggcagg catcacagca tattcggcat aaccacctag attgactaat
     8341 ccgtatactt ttgtcccagg agtaaaagtg gagatatcac ttttattctc aactacctct
     8401 ccagctactt cgactcccaa aatagggtag ggaggtttca aagagactga ttctcttttc
     8461 ataatatctg ttcgattgac agctgctgta tggactttga tcagtaattc gccttgtttt
     8521 ggtttaggaa caggcacttc aatttgttct aatacatcta cagaaccagg atgcttgatt
     8581 gaaatggcac gcatggatct attcctcctt tgcccattct tggaatgctg tattcaactc
     8641 tttgctacct tcagaaagta ctagagtcgt acgagaaata tccgtttctt ccactagagc
     8701 ggcaagtaca gcagcaactg tagagcgagt gatcgttttt gatgccttct cattaggctt
     8761 agttaattga atggaagtaa cttcttcatc gttagtcaat gtgactggtt gaagaatgac
     8821 aaaatctaag ttagttcgtt tcagccattc atctgcataa tgtttagtaa tataataatc
     8881 tgtcatggac tcaggccatt ttgctggttc atctgcataa acagcactga ccatcagata
     8941 gcgagagaca tgcgcatttt cagctgcgat cactgttttg attgcgccat ccaagtctac
     9001 ttgcagaaga ttctttcctt gagagccggc agcaaaaatc aatacatcga tgcctttgaa
     9061 tgcttcggtc attttttcca cggaccaagt taaatcaaaa gagacatacg aaacattctc
     9121 tttttttact aatgtttggg aagcaacatc tctcacccct gcaaaaattt catgggaact
     9181 tggagctaaa tcttttatca ggtgtcggcc aatttgtccg tttgcaccta caacaaaaat
     9241 tttcatttgg atcatccttt cgacgtcaaa tctttccatt caatagtaac accaaaagag
     9301 aaaaaaatca gagatcggct acgatgacta tcagttagta agagaagggt gcttgaagta
     9361 tcttaacaag acattgcata ctgctgcagt cgcaagacct gcgacgattc cttcaggtat
     9421 accacttgta aaaataaccg ctagaatagc tgaataaaca gcatttaaat ttgttccgat
     9481 gactttggca taatcttgct ggaataaaaa gtagatcata ttcatcacta aaatcgtatt
     9541 ggtcaatgaa ccggaaagtc cagctaagaa taaagaaacg gaatctgctt tttgtttcat
     9601 tagtttgcgc agacctttat aaacgaaata aggaaccacc ccaatcaaga tgcgaggaat
     9661 aaacgcgatc agcaaggctt tccagcttcc atgttctgtt ccgatgactg ggataaacgg
     9721 agaaaagaca aaagacaaag gtgtttggat aactgtgcta cggatcatgc tgatcagtcc
     9781 aaatgtaccg ccaagaaaag cacctagtct tggtcctaaa acgatcgaag caatgattac
     9841 aggaatatgc atggttgttg cattgattgg accgataggg ataaaaccta aaggcgtaac
     9901 agctaataaa atcaaaatag ctaaaaacat cgcagttaat gtaaagtttt ttgtattttt
     9961 cataagtact ccttttttct aagcatttct ttcattaaga gtcagcatga cctgttcgat
    10021 gatcgtctga atatcagcta aggcaccttt tccaaaatct ccacaagcta aaagagattc
    10081 tcttggttca atttcctgat agccgacaga tctcaatgtt tccagattac gctgagtgat
    10141 cgggttttga tacatattcg tgttcatggc aggggcaatc aattttggtg ttcccactgg
    10201 aagcgccatt gcgactgttg aaagaagatc gtctgcaatg ccgtttgcta gcttgccgat
    10261 aatgtttgct gtagcaggcg cgatgagaaa caagtcagct tgttttgcta gttcgatatg
    10321 attgattacc tgcggatttg attcttgcat gacgtctgta tggactgcgc gcttcgacag
    10381 agattgcaag gttaatggcg tgataaaatg tgtgctgctt ttagacataa tcacatctac
    10441 ctgggcacct aatttgacga attgacttgt aagatcagcg cttttgtaag cagaaatact
    10501 tccagtaacg cctagtaaga tctttttcat tttgattcct ccagtctaat tttctcagta
    10561 atcaatgcag caatctcaga tttactttga gcttcttcca ctgttccatc tttagataag
    10621 agatagccgt ggtgtgtctc gccatggatt tccgtcaaat catttgcgaa aataaaatca
    10681 gttttgttat ttatcagact attttttgcg actgccagaa gagattcctt tggtacatct
    10741 actaatagtt tgaaaccaat gatttttgct tttggctgcc attcacgtag ataagaaatg
    10801 atttttggtg ttttcttcaa aacgagcaca agatgctcgg tgttagaaga gatctttgaa
    10861 acagtggtat ctgtctgttc attttccgca aaccaattgt ccagttcttc ttgcgttgaa
    10921 gaagtgggta ggttttttgc cagctgttct tctgaaaaac taaaagcagg agtaaaatca
    10981 ctgactgcca tactgtggat aatcgcatcg tagtgttctt ttttcgttag ttcttctaat
    11041 tgtaaaaata agtccagtgc agattcgatc gtataaatcg ttatattgga gtgtcttttc
    11101 ggtttcagtg cttgtttcgt agtcacgtaa tcgattgtgg tatccggatt ggcagctaaa
    11161 taatcagcta atgcttgccc taatcgtcct gtcgaatgat ttgtaatagc acgtacttga
    11221 tcgatttttt cagtcgttcc tccagctgtg attagaatct tcatttatgg tcacctacat
    11281 ttactagtgt tcttccttgg tgtgttccag caagtagttt agatgctgtt tcaggcaatt
    11341 gatccagagt aatctcttgg acgaccagtt catctgcaat ctgcaaatcc gccatctgtt
    11401 gccataaaga aagacgttga tctattggta cattgacaga atcaattcca atcaactgga
    11461 tgtttcgcag aataaaaggc aagacagtcg cgtttagttt gattccccca gcattgccac
    11521 ataaagctac tgcaccgtta taagagatca atggaagaag actgcttagc tgctcgccac
    11581 ctactgtgtc gatgacatag tcgatttgct gttttcctaa agcttttgtt gtctctggca
    11641 gaaattcatc aggtcgtacg acttgcaaag cacctagact ttttagccat gtgacagact
    11701 cttcttttct ggaaaaggta atgattgact ggaatcctag tttatgtaac agggctatcg
    11761 ctgtactgcc tacaccgcca gaagcaccag taacgacaac ttttttatcg gaggtcatac
    11821 cttgacggat taaagcgttc acacacaaca tagcagtaaa ccctgctgta ccaaggatca
    11881 tcgcttgacg cagcgtcata ttttttggta gaggaactaa ccagtctcct ggtacttttt
    11941 gatattggct ataaccgcct ggatgggtga cgccaagccc aaaaccagta gcaagtacaa
    12001 gatcttcttt tgaaaaacgt ggattgttac tttggacgac agttccggat aaatcaatcc
    12061 ctggagtcat cggatatgtt cgtatcacct gaccagactc gctcattgcc aatgcatctt
    12121 tataattgac atcagaatag gcaattttta ccaagacttc attttcagcc aactcagtaa
    12181 atggcagatc actgattgct gtatggaaaa caggttcctt tattacctga aaagatcgaa
    12241 aagcgttcat tcgtgagaca ctccttttaa aattttcttt tatcatacca taaagcctac
    12301 tcttttattc ttgttcttcc gtaaatttag acaaaaatta ggtgaaaaat aaagaatcaa
    12361 acaactagaa tttattccaa aagataaaga aatattcagc aaaaaaaatt ttacaaaggg
    12421 ttgccttttt caataaattt cgtatactaa tacgagtggt agtaaacagg aagtttacta
    12481 ttagaaaact tcgattcgga ggaaattatg gaaattggtg agaagttaag aaatttgcgc
    12541 atccaaaaga atttgacaca agaagaacta ggcgaacgca cagatttgtc aaaagggtat
    12601 atttcccagt tggaacgaga tttaagttca ccatcaatgg aaacattctt ttctattctt
    12661 gaagtcttag gtgtgactcc agaagaattt tttcatcaag aagcagcgaa tctgcaagtg
    12721 gtttattcaa aagaagatca tacggtttat ttcgatgaag aaaacgggta tgaattggaa
    12781 tggctcgtgg ctgattcgaa tgaaaaagaa atggagcctg tcttgctgac ttttgaaggt
    12841 gcaggagaat ataagacgtt tgaaccttca ttatctgaaa cgtttatttt tgtattagaa
    12901 ggggaattag agttaagctt aggagagacg gtctatgtgg caaaagcagg acagtcgatc
    12961 tattatcaag cgacaaaaca acatcaatta aggaatcatc tcaaaaaacg aacaaaagta
    13021 ttgattgttg caacgcaatc atatttgtaa tatagggggt aaaaacgtgg ggaaaccaat
    13081 catttcattt gatcaagtag tgaaacgcta tgatgatgaa acagtattaa aaaaagtaag
    13141 ttttgagatc gaacaaggaa aattttatac actgcttggt ccttccggct gtggtaaaac
    13201 aacgatccta cgtattatag ctggattcac cgaagctaca gaaggggaca tctattttga
    13261 agggaaacgg ttgaatgatt tgccagctaa taagcgacaa gtaaatacag tcttccaaga
    13321 ttatgcactt tttcctcata tgaatgtttt tgataacgtt gcttttggat tgaagatcaa
    13381 gaaaatgtcc aaatcagata tcgaaaagaa ggtaaaagat gctttgcgta tggtccagct
    13441 tcctggatac gaaaaacggg agattagtga aatgtctggt ggtcaaagac agcgtgtagc
    13501 gattgcacga gcaattgtaa atgaaccgaa agtattgcta ttagatgaac cgttatcggc
    13561 gcttgatttg aaactacgta cagatatgca gtatgaactg cgggatctgc aacaacgatt
    13621 aggaatcacg tttatttttg ttactcatga ccaagaagaa gcgttggcaa tgagtgatga
    13681 gatttttgtc atgaataaag ggaaaatcgt ccaaagtggt acacccgtag atatttatga
    13741 tgagccaatc aatcatttcg ttgctgattt tgttggggag agcaatatcg tggacggtgt
    13801 aatgatcgaa gataatctag ttgagtttgt tggtaagcaa tttgaatgtg tcgatggcgg
    13861 gatgcgtcta aatgaaccag ttgaagttgt tttacgccca gaggatttga cgatcacgac
    13921 accagataaa ggaaaactag tcgtaacggt cgatactcag ctgtttcgtg gtgtccatta
    13981 tgaaatcatc tgttatgatg aacagcaaaa tgaatggatg gtccattcaa cgaaaaaagc
    14041 taaagaagga agcaaagtag gattggcctt tgagccagaa gatatccatg tcatgcgttt
    14101 caacgagtct gaagaagaat tcgatgcacg tcttgacagc tacgaagaat aggggggaca
    14161 agaatgaaaa caatgcgcag gatctattcc gtcccttata ttttgtggct cggtttattc
    14221 gtgatcgcgc ctgtattaat gatcatttat caatcttttt ttgatatgaa tgggcaattc
    14281 acgctgaata attatctatc ttattttacg tcggggacat cgctttctat gacgatcaat
    14341 tctgtatggt atgcattttt gatcacgttt ttcacgctga tcatcagtta cccgactgct
    14401 tattttttaa caaaactgaa gcacaagcaa ttatggctga tgctgattat tttgcctaca
    14461 tgggtgaatc tgctgcttaa agcttacgca tttattggga ttttcagtgt gcacggcagc
    14521 gtgaatcatt tctttgattt tatcgggatc gggccgaaac agatattatt cacagacttc
    14581 agttttctgt tcgtggcaac gtatatcgag attccattta tgattatgcc aattttcaat
    14641 gcattggaag agatgaatcc ttctttgatc agtgctagta gagatttagg cgcgaatagc
    14701 tttgagacct tccgacgagt gatttttccg ttatcattaa atggtgtgaa aagtggtgtc
    14761 caagcagtat ttattccttc tctttcttta ttcatgctga ctcgtctgat tggcggaaat
    14821 cgggtgatca ctttaggaac ggctatcgaa cagcatttct tggttacaca aaactggggg
    14881 atgggttcta caatcggtgt gattttaatc attgctatgt tcatcgtgat gctcctgaca
    14941 ggcgagaaga aaaaaggagg tcgctcataa atgaaaaaat ttaaatggtc gtatctttat
    15001 ttagggatcg tctttttatt cttatatgca ccgatcttct atctgatttt ttattccttc
    15061 aatgaaggag gaacgatgaa cagctttaca ggatttactt gggaaaatta tgaagctgtt
    15121 tttgaagata cacgtttgat cattatcgta ttgaatacgt tcatgctggc tttcttatct
    15181 gcattgatcg ccacgatcat cgggacattt ggggctatgg gaatctatta cacgaaaaaa
    15241 cgacgtgcac ggacagcgtt gttgagcatg aataacatct tattagtctc tcctgatgtt
    15301 attatcggtg ctagtttctt gattttcttt acactactag gattcggatt aggttttcag
    15361 agtgtattgc tttcccatat tgctttcagc attccaatcg tcgtcttgat ggtcttgcca
    15421 aaattgcagg aaatgaacga ttcaatggtc gatgcggcta gagaccttgg tgctaataat
    15481 ttccaagtag tcaaaaatat cattttgcct tatctttctc caggaatcat agctggatat
    15541 tttatggcat ttacctattc tcttgatgat tttgcggtta catttttcgt cacaggaaat
    15601 ggctttacga cgctctcagt agagatctat tctcgtgcaa gacaaggaat cagtttagaa
    15661 atcaatgcgc taagtgcgtt agttttcttg ttctccatga tattggtcat tggatactac
    15721 tttattagta aagaaaaccg tccaaaacgg ctgaagaaaa acagaagagt acgcgagggg
    15781 gtggcacggc tgcgatgaaa aaattacaat ctctgttttt aggtattctc atcattattg
    15841 cggtgctgct gcttggtgtt cgtcaacttg aaaaaacaag tggcatgagt ggagcaaagg
    15901 tacttaccat ctataactgg ggagattata tcgatcctag tttgatcacg aaatttgaaa
    15961 aagaatatgg atacaaagtg aattatgaaa catttgattc taatgaagcg atgttcacaa
    16021 aaatccagca aggtgggaca aactacgaca tcgctatacc aagtgaatat atgatccaaa
    16081 aaatgatcaa agaaaaacta gtacttccat tagatcattc gaagatcaaa ggattaaata
    16141 atattgatcc acgattttta gacttggatt ttgatccaga taatcagtat tcgattccat
    16201 atttttgggg aactttaggg atcgtatata acgataaatt ctttgatgca aatcaaatta
    16261 agcattggga tgatttgtgg aagccggaat taaaagacag tttgatgctg attgacggtg
    16321 cacgagaagt tatggggctt tctttgaata gtttaggcta ttctttgaat agtaagaata
    16381 tggcacagct gacagaagca gcaaataaat tgaatcattt aacaccaaat gtcaaagcaa
    16441 tcgtggcaga tgagatcaaa atgtatatga tcaatgaaga agcctccgtg gcagtgacat
    16501 tttctggcga agctgccgat atgatgtggg aaaatgaaca tttacattat gtgatcccac
    16561 cagaaggatc caatctttgg tttgataata tcgttatgcc aaaaaccgtg aaaaataaag
    16621 aaggtgccta tgatttcatc aactttatgc tagaaccgga aaatgcggca caaaatgcag
    16681 agtatattgg ttattctaca ccaaatgaag aagcaaaagc gttattgcca aaagacattt
    16741 cgtcggacga acaattctat ccatctgatg acacgatctc ccatcttgaa gtctacaaag
    16801 atctaggatc gaaataccta ggcatctata atgacctatt cttagaattc aagatgtata
    16861 ggagataatg gcaaaactca gtaagaatgg ggacttatca acgttctaaa gagctaaaaa
    16921 tcgtcctttt tctatctgag ttttccaatc ttctaccaaa agcggatgaa acgccgcttt
    16981 ttttgtgtta ttttattttt tctaccacgt ttttctacca gagaaaagtg gacaaaacca
    17041 ttgtaaaata gggcccgaga cgggctagta aatctaagat tgaaaaagtt acagaaggat
    17101 aaagtaattg gaaactatgc aaatatactt aacccttctg taatctatta ataaaactaa
    17161 tatatgaatc cagttcaata tttgtagcta tgaaaaaaca taaaaatcat attagataaa
    17221 aactaaattg gtagataaat tattttgtca gatatctgag gcaaatattc gactatttgt
    17281 gtttcaaagt aaaaattgga atacaaatat agaatagaca tattgcagcc gatagtttat
    17341 tatgctttta gacacattaa actggaggaa aaaatgaaaa agagcgctaa agatcgagtt
    17401 tttgatgagc tgatacgact aacagggaat atgtcttctg tcactgccga gaaaatttcg
    17461 aagaatctag gtatctctcg tcagaatgcc agccattatt tgacgagatt agtggaagat
    17521 aaaaaggtcg agaaattacc gggaaagcct gttttgtgga agcctttaga tgaatatgcg
    17581 gttgtagata atacggagca aataaacgaa gcctttcatt ctgtagttgg tcatgacgga
    17641 agtctgagag aggtcattca aaaatgtata gccgctgtca aatatccgcc taacggactc
    17701 agtgtattaa taaatggagc cacgggtgtt ggaaaaagtt ttttagccac aaaaattttt
    17761 gaatacgcta tccatgagca aattattgaa aaagatgcac catttgctat cttaaactgt
    17821 gccgattatg cggacaatcc cgaactgctt tcggcaacac tgtttggata caagaagggg
    17881 gcctttacgg gggctgaaaa ggataccgat ggtttattgg caacggccaa caacggctat
    17941 ctttttctcg atgaggtcca tcgcctatcg aaagaaaatc aagaaaagct ctttctattt
    18001 attgatactg gaaactatcg tccagtcggt gaaaatgtaa attggcattc tgctaaggtt
    18061 cgttttattt tcgccacgac ggaaaaaggt gaaaattatt tattagacac ctttgatcgg
    18121 cgtattcaaa ttagtgttat gttgccaact tttgaagatc gccccattcg agaacgatta
    18181 gagctgattc aattattttt tcaaaatgaa gcggatgttt tacaaaaaga tattattgtt
    18241 tcaagagaag ccttgtcttt aatgttatct catcccttta gtgggaatat tggtaagctg
    18301 aagaatatca ttaaaatcag ttgtgcggat gtgtatagtc gaacacaaga agaaccatta
    18361 acgattggga aaaatgagat cttgattcag ttaaatatgc tggaatccga agtagaaagc
    18421 ttgccgattg ctagtttatt gataaagaaa aatcaaaaga taaaaacgga tcgaatcaaa
    18481 ccgtttgatt atgattcgat tttggaaaaa attactcagc tgataaatga aggtaatttc
    18541 aatgaaaatt tttcttcgat aaagaatgaa gtacagcatt tggtgcatca cattgataag
    18601 gattcttttt tatcaatgag tagaaaattg atgattcaga tgtttagaaa ggtctgggta
    18661 tccgttttag gaaaaacgta cggattgacg acgagtggac ctgttgcaga aattattagc
    18721 agatcctatg tcatttcccc aagctataag acagacttaa ccgggataaa tcgtacatta
    18781 gctgcaaatc tacctcggac gacttactta tgtaatcagt tcttggagca tttaccaccg
    18841 ctctcagaaa aggacgagaa ctttctaaga ctgcttattg tcgtgacttt atctgattat
    18901 gtagatgaat ccatcgagct gaagggcctg ttgcttgctc acggagatag tacggctagc
    18961 agcattcaag cagtagtgaa tcaattatgc ggcaattatg tttttgaagc gttggatatg
    19021 ccagtagaga gtaatgtgtc agagattgtc gaatcgacaa ggaatttcgt gaaacggcaa
    19081 gtgaatacag atagtctagt gctgatcgta gatatgggct ctttaaatca aatttacaca
    19141 cagatcaaga acgatttaaa aggggagtta cttcttctga ataatttgac gacttccatt
    19201 gcacttgata ttggcttgaa gatgacgatg aatgcgccat ttaaacagat tgcggaggat
    19261 gcagcagaca agtattcaat caatgttcaa tactttgaag gcttttctca aagtagcaac
    19321 attatcattt cctgtatgtc gggtttgggg atttcggaca aattgaaaga tgtttttcgt
    19381 catcatttat cggatgaatc catcgaagtt ttcacgaagg actacagaga actacgtgaa
    19441 ttaatcgacc aaaatgatga aacttatttt gacaagacaa aattggtcat cacgacttcg
    19501 gatcttccac gttccttttc aattcctaat attaatgttt atgacatctt agacggtgat
    19561 ggagcagcca atttggagca tattttgagt cctgaaatga agccggcaga atttaaccgc
    19621 ttgattcagg agctagtaaa attcttttcg ttggaaggaa ttgcggaccg tttgaacttt
    19681 ctgaacccaa cgatcgtgat gagtgaagtg gaaacagtca tttctaaata tgaaaattac
    19741 tatcatttca ctttaaatgg ccgtgtaaaa ctaaatctct atatgcatac ggcattgatg
    19801 atggaacgtt tattcttggc tcggacagaa aaatctgaag aaccgaatta tgatttgaaa
    19861 ccagatgaag atgaatttta ttatgtttct agaagtattt ttcaatcaat ggagatgaaa
    19921 tataatttta aagtcaatgc ttatgagctt tcgctgctct atgaattatt aggaccgtat
    19981 attcaaaaat aaagtgtcta aaaaagtgtc taatctgttt tttttaggtt agacactttt
    20041 tttaatgtga attaacgtga ttaaaccaat gtttttaaaa gttggcacag gaattgctta
    20101 tataaaagtg aacagaaaga aaggaattaa ccatatgaag aaaattctaa tagcgactca
    20161 cggtcactta gcttcaggct ttcttagcag tattcaatta ctgacgggga aggttcaaga
    20221 gattacggtg attaatgctt atgtggatga gtgtgatttt gaacaggagt tgaatgtatt
    20281 tgtaaaccag gtgaacgagc aggatcagat ttttgttttt accgatttat ttggcggaag
    20341 tgtcaatcag aagattacca aaaccttttt ggagaaagag attgctgtaa ctattttgtc
    20401 tggctttaat ctgccaattc tgctcgaaat agtattggca accaaggaat taacaaagga
    20461 ggatattcag gaactggtaa ataaatgcca acaggaatta aagatgacca ttcttgatga
    20521 ggtacatgta gtaaatgaag aggaagattt tttttaggag gaagaaaaat gattaaagca
    20581 gtgcgaattg atgaacgatt aattcatgga caagtagcga tgacttggac aaagagtcta
    20641 aatttaaccg ggttagtagt agcaagcgat gaggcggcta ccaacgatat tcaaaagatg
    20701 acattgaaga tggctgcacc atcgaatgtc aaagtcatta ttaaaacagt tgatgacgcg
    20761 attcatttgt taaaagatcc gcgggcgaag gacatgcgct tgatggtttt agtccctaat
    20821 gtcaaagatg cggtaaaagt tgcgaaagct ttcccaacgg aaatcgaatt aatgaacgtg
    20881 gggaatgctg ggaaaatgac accgccatcg gaagataaga aaaccttatc aaaggaagtg
    20941 atgttaacga cgtcagaaat tcaagactta aaagaattag ttgaacttta tccagatacc
    21001 gtttttcagc ctacaccggc gatggaaaaa cgttcagcta tctctatttt gagtgatttt
    21061 tagaaaaagg aaggagaaaa attatgtatg atgcatttgt agtcgctttg gccgttttta
    21121 ttggagttgc tggacatgaa atgttcggga tgtccatgct gagtcgtccg attgttgttg
    21181 ctccgttagc aggagcgttg atgggggatt tgcagacggg gttgattgtc ggggcgtcac
    21241 tagaagccat ctttatgggt gtcgtcaata tcggaatctc tagtacggcg gagccttctt
    21301 tggctgctgg gctggctaca gcgttcgcaa tcaaaatggg aggaaacgtg gatgcgatta
    21361 ttcccattgt ctttccacta gcagtattag gattacagtt aatgaatatg attttttctt
    21421 ttgtatgtgg accgatggct gctaaatttt tcaaatttgc aaaatctggt gatcaaaaag
    21481 gaatcatcaa tctgcacttc tttatgtggt ttgtccacta tgcgctttat gctcttattc
    21541 cattctttgc cgttttattt ggagcagatg ttgtcaaaag cgtcttggat aatattccag
    21601 aggtcatcat gaacggatta acagtcgctg gaaatctgct gccggcagtt gggatggcga
    21661 tgctgttacg gatgctttgg agtaaaaata ttgctgtgtg gtttttcttt ggggccgttg
    21721 ttatggcgta tctcgagtta ccattgattg caattgccgc agttggaacg attattgcaa
    21781 ttgttatagc ccaaagagat ctacaactaa aaaatatatc tgttcatgca gttcaaagcg
    21841 atgctgctgt aaatgcaacg cttgaccaag aagaggagga tttctttcaa tgaaattagc
    21901 tgatggaatt tctaaagatg agaaaaaatt ggttcggaag atgttttggc gctcgatgac
    21961 tatgtatgct tcggtgaatc cggtgacgat gggcggcggt ggtttcgcct attctatgat
    22021 gcccttcatt aatcatttct acaaaagtga agaagatcga gctgcggcgc tggaacgtca
    22081 tacacagtat ttttcgacga ccattccttg cgcgtccttt gtcatgggga ttgcggcatc
    22141 gatggagaag gaaaattctg aaaaagctgg ttttgacgtg gaaagtatca acgcgatcaa
    22201 aacgagtttg atgggaccat tggctggaat tggcgattca ttgttctggg gagtttggcg
    22261 tgtcgttacc gcgggactag cgatcaactt agccaatgcc ggaaatattt tggcaccaat
    22321 tatcttttta gttatgttca atatacctaa ttacttgatg cgatactatg gcggcgtttt
    22381 aggctattca ttaggctcta aatatattga aaagctgtat gcgaacgggt taattgaaat
    22441 tctgacaaaa gctgctagta tcttgggtct gatcatggta ggtgcaatga cgatcagtat
    22501 ggtcaaattc aataccgttt tgagcttttc aatgaagggc gaagaactaa tgaatgtcca
    22561 agaaatcctc gatagtattt ttaaaggaat tgtaccgtta ttggtaacat tgagctgttt
    22621 caaattacta gataaaaaag tcggcgtcat caaaattatt tttggaatgg tcgtcttggg
    22681 aattttattg tcattacttg gaatcgcata gtaggaagct gcagctacta ggctgcagtt
    22741 tttttagcaa ggagggaaaa gatgactatt aatgaagtaa tttattcacc caaacaccca
    22801 ttttttaatg ctgagttaaa cgacggaaat gtgactactt caaacgaata cagctactat
    22861 cggaatattc ctgatgtaaa gggattgacc ttcgatgtaa gtaatcaaaa gacattagca
    22921 aaccttgatg tttgcgggac gattcaaacg ttgacctttt atcgagaaaa tttactaact
    22981 gaggaaaaac caggtgtttg ggtcaataaa cagctctctc aaaccaattc gttatcctta
    23041 aaggttgaag taaacgggat tgtctaccat ttgtcagaat cggatcatcg tattgaagtc
    23101 gatgtgattc aagactgttt gcctagatat attcatcatt attcgacgtt taaggtcatt
    23161 gtagtatcct ttgctcccat actggctaat aagcgtttaa gtatgcttgt tcaacaggtt
    23221 tacattgtga atgaaacaca cgaaagcctt caagtttcag tgaaagatgt gccttcgtat
    23281 caagagaagt attcggatca gcaaaatgtg ttgatttctc aaaaaggaaa taaggacacg
    23341 atcgcacaac aggaagtggc aagcttcgcc attgcttttg tggacccaaa tgcttttgaa
    23401 gaagtaatga cttttcagga atctgatatc gaaaaatggc tgaaggaaac attgaactat
    23461 tttgctcagc tatttgggca gctgtcaatg ccaaacgata gagttgtcca tctctatcgt
    23521 cgtgcacttt atcaaagctt ttctagtttc ggtatgaatc gacagggaca ggtcgtcggc
    23581 agcaattggg gcagctatcc tgctactaat cgaatttgga ataaggatat gtattacgca
    23641 tcattgccat tcaccatgtt tgaaccggag ttatgtcaaa aaacggttct atggtttgat
    23701 caatatggcg ttaagtttcc tggttcaaaa tttacaggag gtatcaatca ttctctgagt
    23761 aattcgttat ccagtgcgtt actggctagt ctttattttg aacatactgg ggatacaaaa
    23821 ttctttgagc ggtgtccgca ggttctactg aatgcttcaa gaattattga ggacatatta
    23881 gctcaacgtc ggtcagggga accaatgctt tttccatctg tttggttatc agacgccttt
    23941 gcacttggaa agtatcatac cggcagcaat ctttgtcttt ggaaggcctg tattggactt
    24001 gcagaaattt ttgaagccct agaacaactg agtcttagca agcgatacaa aaacattgcc
    24061 tgtaaactaa aggaatcaat ttgtaaacaa atgactatcg atggtccttt tggtgagcaa
    24121 tttttggagg gaatcggtga tgaggagaaa acaacctatt cagtgaagca ctatcaaaaa
    24181 ccgattcttg agcaagggtt aatcttttta agtgatgtga ttgtggatgg aaaaattaat
    24241 ttattgatgc atgatggaga agaatcagac actacgttga tgccttttta tcaattttta
    24301 gataataaag atcatttata tcagaacacc atggcctttt ctgctagttc tttcaatcca
    24361 acctatagcg aggaaatcaa aggcatcact tggggattag aatccggcgc cacttttcct
    24421 ggctttatca ctgttttaat gagcgagctg cacaaccctc aagctttcgt aacccgatta
    24481 gaagaactaa tttgtttggc agatttagac ggttcgtggt ggtggtggcc gtatcgctta
    24541 gaggctcaac aaggagaagt cgtgcgagac tttggctgcg gcaaatgcgg ctgggcatcg
    24601 ggtctttttg tcagcctaat gatcagtcaa tatttcggat tgaaattcaa aaaaggagta
    24661 ttgcaaattg atcctgttga taatttaacg ttttcttgga agaatttgaa gttcggtcaa
    24721 gccttcattt cgattgaatg tacgcaatcc gagttgagta tttcaaattt gtcagaaaag
    24781 ccattgaaaa taagtgatac gaaaaaaatt cttcacgtag aaaagggaaa aacgattcac
    24841 attcaaagga gaaaaagatg agtatactaa aaaatattac ccaatttaaa aaaatccaga
    24901 gtcgagcaat cactcccgaa aatccaacag gcgagaaagg taaagctgcg atgttgccaa
    24961 gcgagctagg accaagccgc aaaggtcgtg gcgcaattcc gctgacttct ggtgaagaaa
    25021 ctgtgattgc ggatattact ggaacgggaa taattcgtca tatgtggatg acgattcgtg
    25081 atcgaacaga atttggcagt tttgttttac gtgatttaat cttaagaatt tattgggatg
    25141 ggtcggatag ccctgctgtt gaaagtcctt taggggattt cttttgtaat gggtttggag
    25201 agcgttgcga ggtgaactcg ttgccgatag tggttaatcc tacagggggc tttaattcct
    25261 atttcgaaat gcctttccaa acatccgcta aaattacgat cgagaattta catccgaagg
    25321 atatgtcctc atttttttat acgataaatt acgctttggt ggacgaattg gaagaaaata
    25381 gcctatattt tcacgcaaat tggcatcggg aacgcattac caaattacag gaggattata
    25441 agttaattga tcgattaaag ggtcaaggct attacgtggg tacttacctt gcgcttacct
    25501 gcctagaacg ttattggtgg ggcgaaggcg agtttaaatt ctacattgat ggggatagtg
    25561 agtatccgac cgtaacctca acaggttcag aagattattt tggcggggcg tgggcctttc
    25621 atgagtacga tgagttcgga cgtccacatg cgaaaaacta ttcaacagcc tttttagggt
    25681 atccttacca atcaaataga gatgccacaa gagatcgttt tgaaacggga aaattgaatg
    25741 ccgttcatgc ctttggtgac gacgcaatgc cacgacatgg tctttatcgt tggcatcttc
    25801 aagaccccat ctgttttacc gaagatttat cggtcacttt acaacaaatc ggcaacgatg
    25861 atgttcgctt atttgagcgg caagacgatg ttgctagtgt cgcttactgg tattcaacag
    25921 aagcttcagg aaatactaaa cgtcatttca ctgatcgaga acgcttgccg cgttaatgaa
    25981 gtgtttttca catattcgaa gggaggaacc tatgatgata tatggggcaa ttgaagctgg
    26041 agggactaaa tttgtctgtg cagtcggtac tgaggaatta acgattttgg aaagagtcag
    26101 ttttcccaca acaactccag ttgaaacaat gaagcaggtc attgattttt ttaaaccttt
    26161 taaggaacaa ttggcaggca tcggggtcgg ctgctttggt ccaattgata ttcaatgcaa
    26221 atcaacgagt ttcggtcata tcacatcaac accaaaactt gcttggcaaa atttcaattt
    26281 tgtaggaacg ctaaagcaat atttcaatat tccgattgaa tggacaacag atgtcaatgc
    26341 ggcttgctat ggtgaatatg ttgctggttc tggcaaaggg ttagcaggtg ttgcatactt
    26401 cactgtggga acaggtatcg gaggtggtgc cttgttcaat gggactttcg tggaagggtt
    26461 cagtcatccg gaaatggggc atatgttgat caagcgacat ccaaaggaca atttttcagg
    26521 aaactgtccc ttccaccaag attgtttaga ggggatggca gcaggaccag cgattgaaaa
    26581 acggttgggt gtaaaaggcc agaatttatt ggctgacgat tcgttttggc agattgaagc
    26641 cttttacctt gcccaatgtg catacaatac aacactgatg ttttcgccag atagaattat
    26701 ttttggcggt ggtgtaatga aacaagaaca catgaagaaa aaagttcagg ataaatttgt
    26761 tgagcttata aatggatatg ttgaaatacc accaattgat agctacatta ttacgcccga
    26821 attaggtgat aatgccggaa taatcggcgg attagcattg gccagaaaag cggtaagaaa
    26881 taagcaacca taattaatga atgtttcatt gatactcatg tcaaaagtat ttaaccgagt
    26941 aatcaaatga tcaaatgaag ttggataaag cgaaaatgaa ttcaaataaa aaggctctaa
    27001 gtcaaatcgt gttgttttca ttaaatcact gaaaggaaat gcttctgcgt ttcctttttt
    27061 ctttttgttg tgcgctgtat accttgagga tattcactgg tggcgtacac ttaaatagta
    27121 atatattgtg ttactttatg tctgtggtaa tagttatagt tgcttaccaa tgtatgttca
    27181 tttttcgaaa tgttgacttc ataatccttg gcttaatgtt tgaatttttt tggtgataga
    27241 ttttttcagc cgtataaaat aaatcgtaat tctattatag agagttgtga ttataaaaag
    27301 atagcaagaa aaaaaaagaa agtttctata cattttaaat attttattcc tatttctatt
    27361 gctaaaaaag tagaaattct atatttacct ttaactctcg cttctcttgc aaatgtagtt
    27421 agcattttaa tcgataataa actcaggtag ttatattacc ttgaaatgat tgataatttt
    27481 gtcacttcta ttttttttgc aataaatttt ttattttagt gaaaaataag aaactatttc
    27541 tttgaaggcg ataagttaga aaaatattat tgtagtcttt tctttattag gaatcatcac
    27601 tgttgtatct tattaccttt tctgtttttc ttattagaga aaaataattt gagaggtaga
    27661 tagtttttat tggaggaagt
//
LOCUS       DAZUJR010000033        27545 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.033, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000033 DAZUJR010000000
VERSION     DAZUJR010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27545)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27545)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27545
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.033"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(20..964)
                     /locus_tag="ACG804_001332"
     CDS             complement(20..964)
                     /locus_tag="ACG804_001332"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFS4832273.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(1260..2204)
                     /locus_tag="ACG804_001333"
     CDS             complement(1260..2204)
                     /locus_tag="ACG804_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFS4832274.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            2425..3639
                     /locus_tag="ACG804_001334"
     CDS             2425..3639
                     /locus_tag="ACG804_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4832275.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            3661..5676
                     /locus_tag="ACG804_001335"
     CDS             3661..5676
                     /locus_tag="ACG804_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HFS4832276.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(5759..7132)
                     /locus_tag="ACG804_001336"
     CDS             complement(5759..7132)
                     /locus_tag="ACG804_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFS4832277.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(7158..7442)
                     /locus_tag="ACG804_001337"
     CDS             complement(7158..7442)
                     /locus_tag="ACG804_001337"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFS4832278.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(7444..9459)
                     /locus_tag="ACG804_001338"
     CDS             complement(7444..9459)
                     /locus_tag="ACG804_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFS4832279.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(9638..9943)
                     /locus_tag="ACG804_001339"
     CDS             complement(9638..9943)
                     /locus_tag="ACG804_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HFS4832280.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(10032..11063)
                     /locus_tag="ACG804_001340"
     CDS             complement(10032..11063)
                     /locus_tag="ACG804_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFS4832281.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            11270..12145
                     /locus_tag="ACG804_001341"
     CDS             11270..12145
                     /locus_tag="ACG804_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFS4832282.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(12297..13139)
                     /locus_tag="ACG804_001342"
     CDS             complement(12297..13139)
                     /locus_tag="ACG804_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFS4832283.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(13231..15108)
                     /locus_tag="ACG804_001343"
     CDS             complement(13231..15108)
                     /locus_tag="ACG804_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFS4832284.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(15105..16526)
                     /locus_tag="ACG804_001344"
     CDS             complement(15105..16526)
                     /locus_tag="ACG804_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFS4832285.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(16529..19918)
                     /locus_tag="ACG804_001345"
     CDS             complement(16529..19918)
                     /locus_tag="ACG804_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFS4832286.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            20175..21566
                     /locus_tag="ACG804_001346"
     CDS             20175..21566
                     /locus_tag="ACG804_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4832287.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(21639..22286)
                     /locus_tag="ACG804_001347"
     CDS             complement(21639..22286)
                     /locus_tag="ACG804_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFS4832288.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(22294..22980)
                     /locus_tag="ACG804_001348"
     CDS             complement(22294..22980)
                     /locus_tag="ACG804_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4832289.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(22986..24059)
                     /locus_tag="ACG804_001349"
     CDS             complement(22986..24059)
                     /locus_tag="ACG804_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4832290.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            24281..24955
                     /locus_tag="ACG804_001350"
     CDS             24281..24955
                     /locus_tag="ACG804_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFS4832291.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            24960..26300
                     /locus_tag="ACG804_001351"
     CDS             24960..26300
                     /locus_tag="ACG804_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFS4832292.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(26449..27435)
                     /locus_tag="ACG804_001352"
     CDS             complement(26449..27435)
                     /locus_tag="ACG804_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HFS4832293.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
BASE COUNT         8022 a         5213 c         5009 g         9301 t
ORIGIN      
        1 agttcatatt cattgtttct tataatacag tgttcaatac ttctcttaaa gcacttgttg
       61 atttgctgaa cattgctttt tcttcttcgt tgattgataa ttcaacaact tcacgaacac
      121 cattttcgtc aacgattgat ggcacacctg taaagatatc tttttcgtcg tattcaccag
      181 ttaaataagc agatacaggc aatacagctt gttcgttatt caagatagct tttacgatac
      241 gtgcagtact cataccaata ccatagtaag ttgctttttt acgatcaatg atctcataag
      301 cagcattacg gactttatca gcaatcacat ctaattcatc ttgggcaata cgatggtctt
      361 tttctacaat ttcaaacact ggtttaccac cgacagttgt atgtgaccat gcagcaactt
      421 ctgaatcacc atgttcacct aagatatagc cgtggacgct gcgtgggtca acttttaatt
      481 tcaatgcgat ttctttacgg aaacgagttg tatccaatgt tgttccagta ccgataacac
      541 gtgatgttgg cagaccagat tcgttccaag cgatatatgt caaaatatct actgggtttg
      601 aagcaacaac gataataccg tcgaatcctg atcccatgat ttcttttacg atttggcgca
      661 tgattgacgc atttgtttta actaaatcta aacgagattg accaggtttt tggttgatac
      721 cagctgtgat aacaacgata tcagcatctt tacattcttc atagccacct gaccatacag
      781 ccacattttc atcgccccaa gccataccat ctaaaaggtc caatgcttcc ccttctgctt
      841 tttcttgatt cacatcgatc aatactaatt cattagagat tccttggttg atcattgcat
      901 aagcgatact tgttccaaca aaacctgtac cgacgattac tactttacga cttgtttttt
      961 tcatgaataa acagctcctt ttcataacta tttgttactt tcatgaaaag tatagtcttg
     1021 tttattcatt ttatcaacat gttaattata atagttgtta ttataatttt tgatggaaac
     1081 gaattcctga atacgcataa cagataaatg acaaatgttt acacctatat cccctgataa
     1141 tacaaccaaa agtttagaac tgaaaataaa tccaaaaaaa ttcgctgcaa cgatataata
     1201 agacagcaat cgcacctaaa acaattttcc ttcatatgct ttagtgaaag attttcttct
     1261 taatgtttat ttctccattc attgggagta catgttgaat acttcttgaa taatttgaat
     1321 aaagaagtcg tttgtttata tccgatacga ttagcgattt cttccaacga aaaactcgtt
     1381 tcttgaatca gttccaacgc aaagtcgaat tttttcttta gaaccagttc ttgaaaggaa
     1441 gcatcaaaat acattttcaa tttattacta agatagaccg gattgtagcc aaaatgagct
     1501 gctgtttctt ttaacgtaca agaagtaaaa tgcttatcga tataatctaa tactctaagc
     1561 atctcatttt ctgcgcatcc atctgctgat gaaaagcttt gttgttctaa taaatgagtc
     1621 aattcgatca gtaatagtga tgtatagaga tttaacgaac ggatcttatg actgtatgta
     1681 tcaaaataaa tcaacagcat attttcaatc aaatgcgtca aacgacttgt ttttccgccg
     1741 cgaaaatgaa tgaattgtgt atgttcccct ttttcttttg atgcatttat caaaaaagaa
     1801 gaaagtagat tatttgtgct tgccaaatga ttcaatatct ctgtagataa ggtttcttct
     1861 tttaataaga tgttgattaa aatatcctct tgccctgtgt attcgattct ttgagtagct
     1921 tctttatcaa tgatcaccac gtcactttct tccatctcta tcctttctcc attaataatt
     1981 tgtaaacatg taccgctata catataattg atttcaacaa aatcatgtgt atgctcggga
     2041 acttccgcat atcgacggtg tttactgata tgaatatttc cctgttgaaa tagatcccct
     2101 cggtggattt ttggcggtgt ctgaagatgg taagctaagt ttaaatcatt gatattcatt
     2161 ccttgttcac gctgcagagt ttcgattgat tcttcgttac gcaaaaaaaa tgtctaattc
     2221 agctagttcc aattgactcc ctcctttttg taagcggttt ctttcgctta ttagttcacg
     2281 ctgtactgct attatatgca aagctatttt tggtttcata aagactttct atggttggga
     2341 catgaacttc ctgtgattcc gctattgaga gaataaccac ttcatactat atttttgata
     2401 agcgcttaca aaaatgaaag gaacatgctt atgaataaaa agatgatgaa attttctctg
     2461 ctgtcagtct ctcttatttt gacttctgct ggtgcagtca cgtctgcaat tcccagtatg
     2521 tcagctactt atgccacgcg ttctttatct gctgttgaat tattaacgac tgctccctct
     2581 tttatggtca ctatttttgt tttgattagt agttttattg ctaggaaaat cggacaaaaa
     2641 caaactgtga tcatcggatt agtgattgca tcgatttgtg gtatcctccc cctcttctca
     2701 caaagttaca gtattgtctt agcttcaaga gctggactag gtattggctt tggattgatc
     2761 aattctttgg cagtcagcat gattgctgcc ttttatcacg gagatgaacg agcctctatg
     2821 attggttttc aaagtgcatt tcaaggattt ggtgcagctt taatgacatt tgttgcagga
     2881 cagctagtac agttcggttg gcaatatacc tttttagtct acgccatcag cttacctatt
     2941 cttgtcttgt ttgttttgtt tgttcctaca cctgaaacaa ctgaacttca atcgcatggc
     3001 acagccccaa caagacaagt aatcaaaacg aatcctaaaa tgattagtta tggtattttt
     3061 ctcttgctgg tcatcgtggt atataatgct gtatcgatta aattagccac agtcctgacg
     3121 acttattctc taggaaacga aactaatgca gcgaatatct taacaatcat gcaattggca
     3181 agtatggctg ccggagtttg ttttggctgg cttcagacaa aagcacatcg ctatatgctt
     3241 acactttctt tactactgat gggaatcggc tttgtattga ttgccactgt gataaacctg
     3301 tatgtgattg ggtttggtgc gatcctaaca ggaatttctt tttcgttatt cattccttac
     3361 ttattcaacc aagtaagtat ccaagcgccc aagtacgcgg agagtttcaa tacttcaatc
     3421 ttattggttg gcgctaattt aggtactttc attgcaccat atggtttgct ctttctctct
     3481 tttgcttctc ttgggagtaa aacacttgct gttttcgtca atggcagtat cttgctgttg
     3541 attagcgcgc ttattagcct tctagtagta cacaggacga atagaaagac agtgataaga
     3601 gtagatgaag aaataaaaga acaattgaca acaaaataaa tttgatggag gtcgtgtaaa
     3661 atgacaaatg aaaaacataa agatagatgg ctttggtatc ctggagactt tgagatccgc
     3721 catggactgc tacaaaattt ccaacgggaa gaacgaggtt ttgactggcc agcgtactgg
     3781 tacatggatg attgccatcg gaacgtcaag tttaagagat attactttct tgatcaacct
     3841 tccatgttta aagtgacgat ccaaggagtt gggtatgtag aaattaatgg acaaaaacat
     3901 ccatgtggaa aatggctgac ttgtccagct ggtaaagcaa aaattcgtat ctttgtagga
     3961 catacatcag ggctaccagc gatgtttatc gagggagacg aagtaaaatc agatattggc
     4021 tggacagcaa gtaattttat tgaagaatat ccagctggct ggagtccgct ttatgtcgat
     4081 atcgcaaaag atccaaatca aatctattat caaaaagaat gcgtccatcc agtcactgaa
     4141 acggagattg gcggaggaat cttattcgat tttgggcgag cagtgaatgg ctgtgtagaa
     4201 ctaatatctc tggatgacca tatcgaatct atcactctat gttatggaga gtccgatgta
     4261 gaagctatgg atatcgatta ttgctactat aagcaaatag gaatgacaag aaaaatgaaa
     4321 gctcgtaaac gcgcttttcg ctatttgttt ataccagagg tttctactgg aatggttcaa
     4381 cttcaagttt ttcatgaatt tttatctctt tcgaaacaag ctgctttttc aagcgattct
     4441 tctttactga atcagatctg gtcagtatca gaagaagcct tcaagttatg tagtgatttg
     4501 ttttttatcg acggtatcaa acgagatcgc tggatttggt ctggagatgc gtatcaatca
     4561 ttcatgatca atcaatatct tttttttgac gaggaaatca ataaacgaac gatattagca
     4621 ttaagaggac aaaatgaaat caagcagcat atgaatacta tcgttgacta ttcgatcttg
     4681 tggttgattg gtatcgaaaa ccactatatg atgacgaaag actatgaatt tttacgcatc
     4741 gtctacccta agatgcaatc attaatgaga tacttgatgg agcaaacgaa tgaattaggg
     4801 tttatttatg ggagagcaaa agattggata tttattgatt ggtctgaaat ggataaagaa
     4861 ggaacgcttg ctgcagaaca agtcttatta ctgaaagcct atcattccat gatcacttgc
     4921 ggagatatct tagctgaaac atatggagag aacgaaaatt atcatactca tctctatcaa
     4981 gaaaaatatc aactattgaa acaaaaccta tttgactact tttgggatga agaacttggc
     5041 gcttttatcg attgctatga atctgggaga agaaatgtga cgcgtcatgc gaatattttc
     5101 gctgttttat tcgattttgc taacaaagac caacagcaat cgatcttaaa gaatgtctta
     5161 ttgaatgaca ctatcacaca gattactact ccatatttca aattctatga acaagatgct
     5221 ttatgcaaac tcggacagac gaatatcgtc taccaaacga ttcttgatta ttggggaggg
     5281 atgttatctc atgatgcggt aactttctgg gaagaatacg accctactca aacaggaaat
     5341 gaaaagtaca gtatgtatgg agatccttat ggaaaaagct tatgccatgc atggggagca
     5401 agcccaatct atcttttagg acgctatttt atcggtttgt atccaacaaa gccaggttat
     5461 gaagaattta tgatacaacc taatctagat tcatttgaaa cactgaattg tacgctacct
     5521 atcaaagatg gaaagatttc gcttgaaaaa acaaaagata agatcgtgat tacttctgat
     5581 agaacaggcg gaacagtgaa aatgaatggt aaaagttatc ctcttctagc aaaacagcca
     5641 cttgtcttaa caagctattc aaaaataaat gcataaaaca aaaaactgct tgcgacatat
     5701 cagaagactt taaatcttct tctgatattg tccaagcaat ttttattttg aagtttgctt
     5761 aattctgttc tttagaaaca atgtttgttc tttttccggc aaaaagaaag ctagataata
     5821 cgacaagtaa aaagaaagcg atgattccaa ctgtcaaggc tatttgaccg tattctccta
     5881 gtttcccaag tacaagtcct ggtactagat aatcagtatc ggcaaatgta gaagaagcga
     5941 ttttaagatc tcctaatact ggaaggataa ataatggcag ccaactaatc aataagctat
     6001 tgaaagcaga acctaatacc gcccctcttc taccgccagt cgagttgccg aagacaccag
     6061 aagcagctcc gcagaagaaa tgtcctacta ccccaggaat gataactgta gtttgcaagc
     6121 ctatcatagc aaacatggat agtgttccta caaagaagct aacaaaaaag ccaattaata
     6181 cagcattagg tgcatatgga aaaacgatag gaacatctaa tgctggttta gaatcgggta
     6241 cgagtttttt agcaatccct tggaatgctg gaacgatttc tgccaacacc attcgaaccc
     6301 cttgaaggac gataacaaac ccagctgtga atgttccagc ttggatcagt gcaaagatta
     6361 cagcgttgtc tccattgctt agttctcttt caacaaatcc aggaccagct aacaaagcaa
     6421 gtgcgacata tacgatcgac atcaagagca tgatcgatac agtagaatct cgcaaaaagc
     6481 tgaaactttt aggaatcttt atgtcctctg tagaacggtc tttgtttcca aaaaactttc
     6541 cgatccatcc actagaagca taaccgatat ttccggtatg ccctaacgca acttgattgt
     6601 ttccagtgat gttcttcata aacggttgac aaagagcagg cgtaatagtt aatagtgttc
     6661 cttcgaagac cccgcctaat aagatcatcc acaaatttgc agtaaacccc gcgcttacta
     6721 aaatgactgc tgttagacaa gaaacataaa gcattgcttg acctgtaaga aaaatgaatt
     6781 tatatcttgt gaatctagca agtaaaatat tcacgatcat ccctactagc atgatcaaag
     6841 cagtaggtgt accgtattgt tgcaaagcaa tcgccactac tgcttcattg ctaggaacta
     6901 ctccttgagt atgcagagct gtttggaaca tcgaagcaaa aggggttagt gaattactga
     6961 ttaaaccagc accgccgatc agtactagga atccgacaaa tgttttgata gttccttgga
     7021 tcacttctga aaatttcttc ttctgaagaa cgagaccaag cagtgcaatc aaagaaacga
     7081 ggatggaggg ctgactgacg attgacacaa acaaattcaa caatttatcc attgatagtt
     7141 cctcccttga atcattttta ttcttttgac aagatcttcg ttactttttc ttttacttct
     7201 tcgctgtcaa tgatcgattg caaaggtacg agcttttcat caggtataga agttagcgta
     7261 tctttcaaag aatgctcaat gaagaaataa tcagccatat cgctagatac acttccaaca
     7321 tccgtatgac ttacttcaaa ctcgtccaca tctgctccaa gatctgcaag tgcttgtttg
     7381 atgttcatct ctaccataaa acttgttcct aatccacttt gacatactgc aaaaattttc
     7441 atatcattcg tctccttttc ttatgatcgc taatatttct tcttttgttg atgcgtgtaa
     7501 taaatcttga agattttgtt tattagaaag tagctttgtt aaatttgcca aagcccgaag
     7561 atgtgcctca ttatcgatag cagctaaaca gatgaacaaa ctaatgggat gggctggatt
     7621 atcaagcaga tccacaggtt gttgaagttt cagcaaagac atccctactt cgtttacgcc
     7681 atcttctgga cgagcatgag gtaatgcgat gtgatcgcca atatggataa acgcaccata
     7741 ctgctccacg cgctcgatca tagctttgat ataactttct tctattttat tttctgataa
     7801 tagcggctgt gcggcaaatg tgattgcttc ttgccagttt tttggttgat ccgataattg
     7861 gatcatttct tctgttaata attcagatag cataggacgt tgatcctcct tcttttctaa
     7921 aagtttgttc attttacgat ttaatacttg atagagcttt tcttcgtcta cgccttcttt
     7981 taattcgata taaggcagta gcgccgacaa caattcttgg gcagaaggca ttgaaaatcc
     8041 tggtatcagc caatctcttt gtacttgatt gatcagctga tttttttcca agtcagtcat
     8101 gattggatgc agaacataga gagacttttt cttatcagta agtgtgagag gtacagtaga
     8161 aaaaataata tcgtaagaag tttcgtcaac ctcgtgtaag cggtcagctg aattagtctc
     8221 tgtaaaaaag atcatcggga ataattgctg aagttcactt tttaagatca atgaagagct
     8281 aatgccactt ggacagacga tcacggctct tatttttcta tttctttctt ctgcgtccgc
     8341 ttttctgatc tctccgccaa atagtatagt gaaaaaacca atctcttctt cagggatgct
     8401 cttccctatt cgtctttcta acggaagtaa tgcttttctt gtcatttcgt agatggaagc
     8461 atattgatgc ttaatttgat cgatcatcac attaggtaaa taaaaagaat aggaaatacg
     8521 aaaataggca gggaccaagt gataaaagac attcatcaat aattcacgaa acgaagcaaa
     8581 ttctacggcc atcaggaatt ccatgcgatg gatgacttct gaagaacatt ccagcaaaaa
     8641 atcaagtgca ggctcctgga catctccttc aacgatcgat gctaagcaaa gagagaaaaa
     8701 tataatctcc gaattttgat gttcggaata gccaaggcca gtcaatactt gtcgactaat
     8761 gtcagtgact gcaagagaag ccaacagttc agcatctttt accagttcca tggatgtttt
     8821 tccaattcga atggttgtca aactcaaata ataagctaat tcatccattc gatttggtgc
     8881 gaatcgaaga tctgatagtg aaatcgtttt atctagcaaa tctctaactt tggcgtaata
     8941 atcaatggaa agggttgcgg ttaaatacgt gagcccaaat cttccagcaa gtgactgcat
     9001 caaacgagca gtgcgatttt ttgcttctct tcttaatatt gcttctgacc ctagcagcct
     9061 aaaaccagtt ttcctagtat acgacagctg acaatcttcc acttctaatt catttcttat
     9121 ctttttgata tctgacagga ctgtcccttt agaaacctga agaaaatctt gaaaatgaaa
     9181 aacagaaaca gacgttgcag tcgaataaac catcaaataa agaagatctc ttcgctcttg
     9241 ttcggtatac acagcttcaa atcgagtaat atccaaaaat ttttctgccc agtcgattgc
     9301 tcggaatttc tttatacgga tacgggtatc atccacatat tcggcaaaag gagttaattg
     9361 tttgatcgcc tcgcttgtat ttacttcgat gatctctgct gctttttcta gactgatttc
     9421 tcttggtgtt ttcaggagat aactaatttt gtagttcaca gcgctgttca cctcctactt
     9481 atattctagt atggtagcgc ttttaaatcg aggggtgttt ggtacaactt acagttggat
     9541 tttttttacg actgtaccga acgatttcta tcgaatggat acagaaaaaa agcaggtgac
     9601 caaatgtctc ctgcttttat gaattgattt cgtccgatca atgatgatca tgtttatttt
     9661 ttgaggtcag ttcttcaaat ttttctttga catcttcaac cgctttttcg atatcttttt
     9721 caaagtgatt gggctcatta ggctttgttt cctcttctac agaatttgaa ccagataaag
     9781 ctgtttcttt attttctgtt tcaccagagt ttgtgccagc taatgattct tctttgtctt
     9841 ctgtttcacc agaattagtt cctgctaaag ccacttcttc ttctgtttta ggggccattg
     9901 aacctcttaa tcgtttgtgt ttttcaccgt cataatttgt catgttggtt cctcctagta
     9961 gttctatact ttttcatcgt acaataagac agtttatgcg tcaaaaaaca aacccgattc
    10021 ttacaaatat gtcatatttt tccttctgat tcttgaatgc ttttgattcc ttcttccaaa
    10081 attttcattt gtaagattgt ttcttcatct ttgatgactt tttctgcgcc attaactaat
    10141 gtctcgtaaa tcccttcgta gacacggctg taatcaccaa cctcggaaat tactttttct
    10201 tcatgataac tcccttgttc atctatatag gtcaatacac cataatgttc gggcaaatcg
    10261 ataccaaagt cttcatgatc aggcatgtaa aacattttca gatgttcttc ttgtcgatct
    10321 tttgtttgtt tcacgaacat cccttttttt ccgtaaacga cgaaacttgg acgttctttg
    10381 atgcggaaat aactggattt tatcgaaatt ttcatatttc catagaaaaa atccagatcg
    10441 aagtaatcat tcattcgtcc tttccctaaa agttgacgta catcatagct gatatcatct
    10501 ggttcgccga aataagaaag aacttgatct actgtatgac aagcatgtcc atataaatag
    10561 ctgttcgcag tagaaaattc atgcgtattt tctggtactt ccggtctgaa ataatcataa
    10621 tgcatttcta cttctaaaat atcccctaat tttccgcttt cgattacttt ttggactgtc
    10681 aagaagtcag aatcgaaccg tctgttttgg taacattgga taaatagacc tttttctttt
    10741 gctaatgcaa ataactcttc tgcttccttt gacgtttctg caaaaggttt ctctactagt
    10801 acattcttac catgttcgag tgccattttt ccatattcat aatgaaattg actaggtgta
    10861 gtgatgacaa ctaattggat ctcaggatca tcccaaagat cagacagctg atcagtatat
    10921 tcgatgtctt cgaatgtttt ccacactggt tcagatgggg aaaaaatttt tttgatattg
    10981 attttgttcg taagttttct tgaaaaaggc aaatgatagc gatttgtact ctttccattg
    11041 ccaagataag cgattgtaag catgagtggt gcctcctttt attgatgttt tcagtatatc
    11101 ctagaaaagc gcagaaagta tttataatag ctattctggt aaaaaagttc agaaaaacac
    11161 ttgttatcat tcggtttggt gaaattaatg ttcaaagtaa ggataaaaat caaaaagata
    11221 gtagcggaac caagtgttta tcagtaagat agaatttgga ggtcagatca tgcttattga
    11281 agaaaaacta acaaaacaag agttgtttac cacgacagag aaacggattg tcgattacat
    11341 ccgtaggaat atcgaagctg cagtctacat gacgattgaa gaattagcaa aagctacgta
    11401 tacttcccat tcagctatca ttcgtttatg caaaaaaatg ggattcagcg gatttaaaga
    11461 attccgtttc gagctggggc gggaagttca tcaattgatt gctcagttca atcaaacgat
    11521 tgatcctaat tttccttttt caagtgaaga tagcactcag caaattgcaa agaaaatggc
    11581 ggatttatcg atccagtcaa taaaaaaagc acaattgcag attgaacatg aagatttaga
    11641 tcaaatcggt aaagtattga acaaggcaca gcgaatcttt ctttttgcaa aaggtgattc
    11701 tcaaatcacg gcaaggaaat tccagaataa aatggtcaag ttgaataagt ttttgatcat
    11761 ggctgaagaa tacagtgatt cttcttggaa tgcagccaat ttgactagcg aggattgcgc
    11821 catttttatt agctacagcg gtcgcatcca tcattatgaa cgaataatga cctatttgaa
    11881 gcatgtagag gcccctacct tgctgattac cggaaatcag cattcagaaa tggccaaaca
    11941 ggctgatatg tgtcttgtta tatcgcagga ggaatatgat tttgctaaag tagcgacttt
    12001 ctcctctcaa attgccttcg attacgtatt aaatacgtta ttctcagtga tatattctca
    12061 aaattttgaa gagaatatcc gcaacttgaa aaacaaacaa gaattgatgc aaaaaggcct
    12121 tcttaaagaa tatcggaaaa cttaagaaaa gatcctcatt tagtaataag aaagatagtg
    12181 tttgataggc tctctttgat atcatcataa aaacaggctg aagttttctt tttcaaacct
    12241 cagcctgttt gtttacggaa cgattcgaat agatatatta tagaaatgag gaatagctaa
    12301 cttctgtttc ttattttgaa cgattgacga aaaagatata taagaaggag gaaaatcagt
    12361 atacatgcag ctaacaatcc atacaggaaa aatcgtttgt tctcggatac tttctgtact
    12421 tctttttgaa cttcttttgc atgataagga acccggtgcc ctctgacaag taagcgatga
    12481 ctgttgacca tataaggtgt acaagttagg agtgtcacga aatcctgccc tttttcgatt
    12541 ctcagatctt ttgtatcagt cggttctacc gtcttgatct gatcgacttg ataagcgagt
    12601 gtccgtccat tgatttcgat atagaaagaa tcacctaaag tcagtttcgg taagtctgtg
    12661 aacaactttg cttgaggcag tcctcgatgg ctggaaataa cggcatgtgt attttctccc
    12721 cccgtaggat aagacgttcc ttccaataat gaggcacctt tttctagcag cacagtattc
    12781 gtttcatcaa aaattggcaa atggacattg atctcaggga tcgtcaaaat accgatcgta
    12841 tgtttctcaa aataggttct atcctttttc gcaggttctt ttttcttagt aaagggatct
    12901 gcacctggat ttccaccttc ttttgctaat tgctggtttt tctttgtcat gttttcttgg
    12961 attttagcca tgacttcttc attttctttg accgcttgtt gctgataatg agagatgatc
    13021 tgctgatcca gataattatt cagcgcgtcg ctaacaaatg gataagctag tatccctatt
    13081 cctgagagaa gcaagaaaag catcagcaga tctagaagtt tccttttctt tggtttcatt
    13141 tgtgttctcc ttgtgatgac tgtttgataa taaaagaaaa aggagcattt gcgtaatccg
    13201 ctgctccttt ttccaattct tgcaaaaaga ctaaatctga ctgtgcttgc gtctagcaaa
    13261 gtacagtcca gcaatcagta gaaggactac tcctgcaccg atatacacat agattccctt
    13321 accgcctgtt gaaggaagtg tacctttgtg tttatttggt attttttcag gagaaatcaa
    13381 ctgtcctgct gttacataag attgttcatc gatagtaaat gctacacggt ttgttaatgg
    13441 aacatatttt tctggcgctt tcgtttcttc cagatagtac gtgccatatt ttagacctgt
    13501 cacatcgatt aaaccgttac ttgtggttgt aaaaaccgtt gctgattctt tcgccgatac
    13561 ccagctgacg gcttttgtgg atgggtcgat cgataaatat ttcgctgtgt cactatcttg
    13621 atcacgaacg acgaattctg ctccagcaag tgtttggtct gatgtaacgt caccatctac
    13681 tttaacaaat cgtttgcccc cagtaacgac atcgactgac ggtggtgttt gatcatttgt
    13741 atgcccgtta tcgacatttg cttggttaga aaatcctttg gttggatctg ctttttcgtt
    13801 caaatgcata tagtaaacga atttcaatgt accgccagga gttaatgaag gaatataatt
    13861 cggatcaact gaaaccgtga atccgtctgt ttgctcagtg acagaataat ttactgggtc
    13921 gatttcttta tttccatcat ataaggcata agcatacgtt cctgaagaat cattatcaaa
    13981 tgttaaagca gcgtcatgag tatcgataag tttgaatgtt gtgtacttgt tttgcgttcc
    14041 ttctttatca gcgataccta atgggatatt gacagaaatc tcatattgaa ttttttcacc
    14101 gattgcgaca tcttttccat tcaattgagg tgttgtttta tcaactttag acgtatcatt
    14161 tttgatggtc ttttctactg gtgtttggct atttgccagg atctcaaaag gcgtgattgt
    14221 ttgcttttca atcatttccg cattatcagg agcttttact tcttctaaat tatattttcc
    14281 aacttctaaa tgattaacga tcaactggcc tttttcaata gatgcctcgg caaagtcatt
    14341 gttgccgatg tcataagaat gaccagtaat gaaatgtttg gctttggttt gatcagttgt
    14401 ccaagtgtac aatccatctg tgacactttg gatgtatttt ttgacgcttg gtgttccttc
    14461 ttctttagaa ataataaatt ctgctccatt tagtgcttcg ttttcggcag taccgatttt
    14521 tgtaactttc aacgttccat cattaccgac tgtattttta gggtagagat ggatagtatc
    14581 tagttcttct gtcccgtatt tataagagcc atctgcttgt ttgatcatct catatacagg
    14641 gaaagctaaa accatgtttg cggcagctga cactccgtct tttggttctt ctttgatcgt
    14701 gtagactgca tctttcccat tttgtttttt aggtaaagat aaagtgacat ttccatcagc
    14761 atctgtcgtt cctgaagcaa ctggtgtacc aggagtcaaa gactggactg cttgttttgc
    14821 tgcatccacg gacgctcctt tatctcgttg cgcataaaat tcttgagtga cgttataaac
    14881 tgaaaatgaa atatcggcta atccttggta ttgatcgaat tcgctcattt ctttcccgct
    14941 gttttggatt aaaggatcgg gtaaatcagt cattttcttt ttatgaagga tgacttgagc
    15001 tgctgtctcc tctgcaaaca ctttttttgc gccgaagctg tttgtgagta atggtaaaat
    15061 aaggaaaagg actcctaaca taacgtttat ttttttatga tttttcattt tttcactcct
    15121 gttctttttt tgataaacaa ccagattgca aagcttgcga ataccatacc aacaacgcct
    15181 aaaagtgtat ttttcgtttc gtttgttttt ggaagaaatg gacggctatt ttctttttta
    15241 ttgactactt tcaatatact gtccgcctct ttatcctcag aaagaaaagt tgaaatggta
    15301 aacggaattt ctgtttcact taaaatataa ccagaaggtg cttcgatctc ttttaatcga
    15361 taacttcctg ttttcaaccc ggaaattgaa aaagcgccat ttttatcgga aatcaggtga
    15421 agcgcatctg attcgttctt tgtccacttg tatccgttgg ctgtttgctg gaggtaattt
    15481 cctgctttgt ttttaataag gaatactgcg ccagctaatc gtttatctgg tttatttgtc
    15541 tcgattttga caaattgctt actccctgta tatacagaga ctttctttgt actgacacca
    15601 aaaccaaaat ccagtgttcc gttgttgttg atttccttgt tcgcctgtgc tgtactgctt
    15661 agctgcatct gataagaaat ggtcagtttt tttccagcat atttttccaa cgaagggatc
    15721 gaaaataaaa catcaaatcc gtgaggtttc ttgtgtatga caaagccttc tgtcagcttt
    15781 tctccattcg atgaaatcgt taaactatta ggtaaaaacg ttaatgcttc atccgcacta
    15841 tctgacaatt cgaacttttg atagtcaagg atatttacag gaattgtcgt atgcaaggaa
    15901 taagtgattt tttcaccaat cgtaaaatca tttctaggct cttctaatac cttctcaaaa
    15961 ggtggatcag ggtagtcgtt ttcttcattt ttaggataca aatggatagt tgaaagtttt
    16021 tgattgtttt gtccatgtac aggaagaaca actaccatat tctctgcctt ttctttgacg
    16081 acttctggta ctttggattc aatgaaaaga tacgctttat ctcttttttc ttgatcttta
    16141 gcggccagag aaaaagaagc gataccatct tcgttgttaa gagttgtagt tgttgcttct
    16201 gcggtaaaca taccggaaga cgcaccgttt tttgcgatct ctgcttgtgc ttcttctacc
    16261 gttttgccct tttcccgtag atggtaaaaa gaatctgtga catcataaac ttggaatgtg
    16321 acaccattta atcctcgata cgtttgtaat aaagcttttt cttgtccgtc atttggatga
    16381 tttttcggca gttgcccgtt tgggaaaagc aatttgtgta aagtaatctg aaccatttct
    16441 gtttctgttt ctgttgctac ctgagtaaaa gctggtttaa atagtaacaa gaagagacac
    16501 atactaagcc aaccaagttt tttcatattt agctgccccc tctttctttt ttcaaaaaaa
    16561 gataccaaat agaaaacgca caaccaatca tccctactag atagattcct aaacggccaa
    16621 ttcctcccgt ttcaggtaat ggtacttttg cctgattcgt gatgtctaaa gaaatctggt
    16681 tgtttttggc tcctggtgac agaacagatt catgatcttg tccatccact tgaattgacc
    16741 catcttcgtg tataactata gtaactggct cttttagacc ttggtatcct tctggtgtaa
    16801 aagtttcggt cagcgtataa gttccaggtt ttaaattttc gaatagaaag gtatctgttt
    16861 cttgtccatc ttttggcgat tctaagtcca tttctggtcc ctgcagtctg aattttgctc
    16921 cttttaatgt ctgtccgttg tcttcttttt tgtgtaccgt tagatcaaac gcttttagtc
    16981 gattttgatg agtgagcgtc catacattat ttgtcatctc ggtatttttt cccgtgtaaa
    17041 tgatttttcc atatttatcg atttggaatt cataatttcc cggcgaagta tcatatccgg
    17101 caggaccagc tgtttcaacg actcgatatt taccaggtgt gagtgaatca aaactggcaa
    17161 gacctttttc attcgttgtt tggctgtcaa ttggctgata agtaccattt gcttcttttt
    17221 tctgtaggga aaatgctgct cctttaagat ttatctcttt gtccgtccct tgcatcgcat
    17281 acttacgtac tgctacagga acttcaacaa aaggattttc aatagtcaac tggatcgtat
    17341 catcggaagt agtgactgtt tttccatcaa tggttaccgt accatcagaa gcgatcttga
    17401 tttcccaagt agtctttttg cttaatccat gcccttctgg agcttttgtt tctgtcagcg
    17461 tataggtcat ttctttttgc aatttgacat tttctggaag agaataggtt ccgtcgccat
    17521 gatctgttag taaagtatca atagaatctc ctgttaattt gaaaacagcg ccaataagat
    17581 ccttttcacc tgtagaggaa tttttcgtta ttttcaagtt taacggtgtg aattgtttag
    17641 tatttttcca tgtcattgca tctatttgtt gagaatcgta tcctggtaca ggtaattctt
    17701 tgattgtttg gtaactgaat gcttgacctt gattattgta ttgaggtagt gataatatct
    17761 cttgataact ttctccgcta tttgcagata atttgtcaat gtctgcacgt tcccacgtat
    17821 ttgttgtatc tttagctggt ttaatgattc gaatatatcc gtttttccaa gctgcagcat
    17881 ttgtcgtatg ttcccgttga atctcaaaag taacttgatc tggacgatca gctagattgt
    17941 tgtcaaattc ttcccataac tttttgatgt gaagactgac tccgggagct ttagcagatg
    18001 gtataccgaa ttcagctaat tcattggtat caatgtttgg ctggaaagtt gtcctgccgt
    18061 tcatttgata ccagaaattt ggatggaagt cctcattttc tgtttggatt ctcacttggt
    18121 aatggatttg gatttcttgg tcttttccta aatagatctg attgctcttg atggtatttc
    18181 cttctatgga aatagatgga gtgaccgttg taggacttgt ccccacactc ttgactgaaa
    18241 gtgtaccagg ctgataaatg aatggttctg cgattggatc atttatttgt ccattgctta
    18301 cagttgctga gatctgtaca gcttttttgg ctaggtattc agagatatct gttgcatgat
    18361 cagctgattc atagtaaaga tcgccttttt catctgatga aaccatttgt cgcatacgag
    18421 actctacttc tgcttttgag agaccagctg ccggatcgct ttgaagttgg atgccaagac
    18481 catgtatttc gattcctcgt tctttgagtg ccatcgcttc tccgatggtt gcgataaacg
    18541 tactgtcgat tcttctggat agattgtttt ggtcaggtgc atcatagatt cttgagatta
    18601 gagaagtatt tcccggccga tcttgcgtat tagaaaactg agttccgtaa taattgctgc
    18661 ttgattgtgc gtgtacccgc tgtactttat aggaaaatgt tggtacacca tccgtcagca
    18721 aaacgatcac ttttttatgt ccatttggaa cggatagcat gcttcctgca tctcttagtg
    18781 ctttttgtgt aaaagtacca ccatttgtcc gtgaaggtgt aatggatttt acttgatttt
    18841 tcactgaatc aaatgaaccc atctgtactg caccgttact gtagctatat ccttcgcttg
    18901 agtagccgac atatcccata ttgattttgt ctgtgatacc gctatctgct aaagtatcga
    18961 caaaacgatc gacaccaatc tttacttcac cgatccgatt attgtcgttc atacttcctg
    19021 accagtctac gaccaatacg agatcaagag gcgtgatatc tttttgtaca tttccacgag
    19081 cattcaaata aacatcaaac aatccgggtg tacttgtttc ctttgcatac tttcgtatcg
    19141 catagtctgc ttgattaccg gttcctccat attcgatata cgaatgggtc cgatcattag
    19201 gatctccatt ccaagaattt ataccatccc attgatttgt tccgttttta ttgccttgat
    19261 gatcaagaac atttgtattt cctgtaggtt gccaactggc tttaggataa gtgccctgat
    19321 catctgttgt atattctgta ggaatcgttt gattagatgg cacactcaca gctggcaagg
    19381 ataatgtagg caatgtaaat gggctgacag aattttcgtt ttcttttgat gattcttctt
    19441 ctatttcgtc tggctttggt actgacacat ctgtatcttt cttattttct gtctcatcaa
    19501 taatgtcata ttctttatta tcgacgatca gcttgtttgc ctggctgtgg taaagtgctg
    19561 gatcgattgg aaaactcaga tcgatagttt gtttagtgtt tgatgagatt tccaacgtaa
    19621 ttttcccgct atttacctga taagcatagc catctccttc ttttctttcc acatcactta
    19681 agtaattttc gactagacca atttcttttt ctatcttttc agcactggtg ttattcgcat
    19741 ttagcttgat gttcagtgct ttttttccag actgatccga aatgacttca gctgaaattg
    19801 tttctaaaac tgttggatca tctgtagtgt ctgctattgc agataatggc acaaagtttg
    19861 ataaactcaa tattatcagc atgaaaataa ctttcagttt cttccctgtg gtcgtcattt
    19921 ttcccctcct ttttcttttt ttctgttttg acgtgaatag tgaaaattat taaaataaac
    19981 aggcgttaca taattttatt tattttaata tgataattat tatacgaagg gcgctaaagg
    20041 gaatcacacc aattttcata ccaattggtt tcatttatga agttgattcc ttcgattaat
    20101 gagcgtttca ttgaaagaaa agggttgagg gagaaaaaca tatgatcagg ttgttggaat
    20161 taaactatag aaagatggaa aaaatcattc gaattctgtc catttctgac aagtggatga
    20221 ctaaaaaaga acttgccaaa cgaattggta gttcagaatc tacatttgta aggtatatcg
    20281 aagagatcaa aatccgctgg ggaacggatg taacgattca atcttcacaa aaattggggt
    20341 atcgtcttga acatttgaat gtaccagctt atttaaatgt tctgatggaa atgtcgcaaa
    20401 gttctacaaa cagtcgttta ttaaatgaga ttattgtcaa tccgggtaaa acgattgagt
    20461 attattgtga aaaaatttcc atcagccggt cttcttttac acgtaagttg aaacaatgca
    20521 atcaaatttt agaaagctat ttattaaaag tgatcgttga ccaaggtttt cagttaacta
    20581 gccttaaaag tgagctccag ttgcgtatct ttgttacctt tttcttttta agttactacg
    20641 gaagacgcac gttgccattt ccaatcgaaa aaaagaagat caaagaaatt atggtcaaga
    20701 ataattgtca gatgaatttg tttcaggaag aaagcccata tgagcaatct ttctttatta
    20761 tgtattttgt tgtgcatctc atgagagaat cccaaggaac tccatttgaa tggaaagctg
    20821 gagactctta tgtacagttg ataaatatcg ataaaaaaga cttcttaatc ttgaaaaatc
    20881 tcttaggaaa attgaagtac agcagctata taaaagtagt gaactatttt gtcaatacga
    20941 ttttttcaga attttcggag aaagaaaaaa atgaaatcag tgagcagata cgaaaaaata
    21001 tgtcctactg ttcgttttca tccgctgatt gcaaagaaaa aaacgaagaa tatgttgttc
    21061 aattattaac gcaaatttat tttttctccc gtattttccc atacgatacg actcatttga
    21121 cgatccgtgc aacttacttt gcacagcaga tgcaacaccg ccagatacgt ctatatgctg
    21181 gatttcgtgc agaacttcaa ttttattcca ctctactgaa tcagaatctg atttattatt
    21241 tatctagcta tatcttttgg atgcttatcg gtaatcctga aattcaccat tatacttctg
    21301 ataaaaaaat actgattatc agcgacttaa gtcttcgaca tagtcaatat attgaagaat
    21361 atatcagtga tattcttgct gtgcataaaa ttcactctga gacaactgct attactgaag
    21421 atcagctgtc gaaatacaat cttctcgagt atgatctgat cgttacgaat caacccattt
    21481 tgaatgccca tgttcctcat atattgattg atgatagtgt gtcattcgca aatgaagaag
    21541 aactcatccg cttattcgag ttatgaataa tcaaaaaaca gctatgtata aaccaccctg
    21601 ataaaaattt caggacaaat acacatagct gtttcttttt attgtattcc ttcagcaatc
    21661 caacgagatt tatagcgaaa gtcttttaac aactcttctt ttgtccaatt atttgcaatg
    21721 agatccgtca aagtgttcat tacgagggtc atggaaaagt ataggaaact aactgcttct
    21781 tccgacgatt gaatggagaa atgattgatt cttaataatt ccagccattt ttcgttcatt
    21841 ggagaatcag ccgatagttc tctacgtttg gttgtctgct gatcatttcg ctgggttaac
    21901 aagtataacc tttgccaata gatactttcg tgatctaagt cgcagcacca ctctaaatat
    21961 ttttcgatcc ccaaaaagaa atgttgtttg ttttcgctaa tgaattttaa gatatcttga
    22021 tggactatgt gagaactgct tttgatcgta tacaaataag catcttccaa atcttgaaaa
    22081 tatttataaa aagcaccgcg cgacatcccc atcttgtcaa cgatttctga gactttgact
    22141 tggctgatgt gctgtgagca aaatatctcc agtaataggt catcgattct ctgtttcttt
    22201 gcgttcgata aattgaaaaa agtttctttt ggcatccaca tctctccttt atctctgatt
    22261 atacgtggat agcccttcat tgtcatgaag gattcattcc ttctttttct cttcttctgt
    22321 caagtaccca tcttccattc gataaacgcg atcactccat tgaatcatac ggacatcatg
    22381 agtaaccata atagtcgctt tttgtttctc atgagcttct ttaactagta atttgacgac
    22441 ttcatatgca tgatctgtat ccaaactagc tgttggttcg tctgctaaga tcaagcttgg
    22501 ctcattatat aaagcgcgag caattgccac tctctgtctt tctccaccag aaaggtcttt
    22561 aggataacta tttttaagtg actggatatc taaagattgc agcaaggaat cgatttttgt
    22621 tgaatcttct ttttttgaag taacttggtc aactagttca aattgttcct ttaccgttaa
    22681 aaaaggaatc aaattagagc tttggagaat aaatcctatt tctttaaagc gtaaatctgc
    22741 tcgttttttt tctggaagct cagttagtga gtgaccgttg atcactattt ctccggaagt
    22801 cggtgtttgc aatcctcctg aaatggtaag gaaagtactt ttacctgaac cagaaggacc
    22861 aatgatgctg acgaattctc cttcctttac ataaaaatca attgctttca aagctgagac
    22921 ctttgtatga ccagaaccaa atgttttggt aacttttttc atcgttaata tttttttcat
    22981 ttttattaac ctcctattgc tgtaattggg tctactttgg ttatcgtacg tatcgaaaac
    23041 aatccgccta gcattgcgac aatgatcaaa atcccactat atagcaacca ttgtgaccaa
    23101 aaaacagcaa aaggcatcgc gcttggtaaa atcagactag tcaaataagc aaacaaaaga
    23161 gcaagcagaa cgcctaccac cccaacaata aaggactgtg ctactaaaga tttagcgatg
    23221 aagaaatttt tgatcccttg tgctttcatt actccaaaaa tagcagtctt ctgaagtgtc
    23281 atcacgtaca tgaaaatacc gaccacggca gcaaccacta agaacaaaaa gtatatcatc
    23341 gcatttaagg tcatattttg ggcagaatag ccaggaatac tttcaatgaa tgtcccaata
    23401 gttaataact gtagaccctt cgatgctttt tctttcgaaa ttttagctga atcctttatt
    23461 acgatcccat tgatcggctg ttcttcttca gaagcaaacg gctgttgtcc atacttcaaa
    23521 gcagtccacg tatctaggga cgcatagatg acgggagaaa ctgtgtaata agtttcagga
    23581 aagataccga caatcgtcaa aggatcgtcg taactgccaa ttttgatcgt atctccaatt
    23641 ttatagcctg aatcagccag attttgagag atgatgattt cattctttgt tttaaattca
    23701 tgccctttcg tgagttttgg taataaaaat gcttctttcg ttgtgccgaa aactgtaaca
    23761 ttttctttgt tttttccttt gattgctccg ctgtacaatc cgattggtgc tttctctcct
    23821 ccttcaatgt atttcagatc tcctcttgtt aattgtgaag ctgcaaatac ttgatttgca
    23881 tcctccgaca aaacaatctc ttgtgcgtcc caatcatcga ttgctttttt aaactcttct
    23941 gaaagtccat tcgctagtcc tgacaacatg aatacgacat acgcaatcaa gaacataata
    24001 ccgacgatca agccatatcg taatttagaa tagcgaattt ctttgatagc tagaaacatt
    24061 tgtttttcct ccctatgata gattgatagt gacaaaatgt cacttgttga atagtgtaac
    24121 tctaaagtga caatttgtca cttgtgttgt ttttttctta tcaataaatt gtctaagaca
    24181 tctttcgata aaaccttaac atgagtcata aaaaatttat ttaagcctta tttatgcttt
    24241 ccatgataaa ctaaagtgac caaatcaatg aggtgggaaa atgattaaac tattagtagt
    24301 agaagacgat aaagtattat ccaataatat aaaagaaata ctcgctgcaa tcggcgagat
    24361 aacacaagtt tatgatggta gtgaaggact gttcgagttg gaaagtggag tttatgatct
    24421 tgcaatcttg gatttgatga tgccggaaat gaatggatat gaagtgttag caaaaatacg
    24481 gaaagaaaaa atacagactc cagtattgat tttgactgca aaagatagtt tggaagataa
    24541 gattgaagga tttgaacgag gtgcagatga ttatctaaca aaacctttct atcgagaaga
    24601 actgatcatg cgcgtgaaag cattattgaa acgctcgcta ggtctctttg atgaaaatgt
    24661 tctgaagtat aaggatatca gttgtgattt aaaaagcaat gaagtcttgt ataaagaaca
    24721 agttttgccc atacaaggaa aagagtttga attgctcgtt tattttttac aaaataaggg
    24781 aatcattttg acaaaagagc agatatttga ccggatctgg ggatttgatt ctgatacgac
    24841 gattacagtt attgaagttt atatgagcaa cttacgaaaa catctgcgaa gtactggatt
    24901 ggataaagaa atcaaaacct tacgtaatgt cggttatata ctgcaaaggg tgtgatgcaa
    24961 tgaatggaga tattacacga aagcaacgta gtcgcttttt tgcgacaaat gtagcagcat
    25021 ttgcttttat cttttttctt ttgggattca ttactttaca gatattaaac caatctgcat
    25081 acagagaaac agatctgtca ttagagaaaa taaattttga ttctcgaaca gtacaattag
    25141 agatacaaag atatcagcaa ggcgatccct ttttaaaccc gactcaaacg gaacaaaaca
    25201 gaacaaacat ggaacagcca ttaatggaac catcaaatga ccgttttaac actcaagtga
    25261 tcttgtggtc taaaaatggt gagatattga ataaagcagc tattggtggg cgtttcaacc
    25321 aaatcaaaga attaaaaatg gatacgaaaa atctgaatac catccaaaat attgaattaa
    25381 atgaagacag tggctcatct gccctctctt tccgttcgat tacgaaaaaa gcggagacga
    25441 atcaagatgg cgttgcctac atccaaattt tagaaaatac aaatcaaatc aagaattcat
    25501 tagcgacttt tcgcacgatt atgattttgt gtatgattgt tttttggatt ctctctattg
    25561 gtatcagtta ttacttgtct agtctaagca tgcgccctat tattctttct tggagaagac
    25621 aaaaagaatt tgttgagaat gcttctcatg aattgcgcac accgttaacg attattcaaa
    25681 atagtttgga acatcttttt accaagccta atcatactat tattgaagaa tccgaaagca
    25741 tcgctcaagc attgtcagag acgaggcgcc tcactggatt gacttcggat ttgctgacaa
    25801 tcgctcggaa tgattctgat cagcagctgc tttcaaagca aatgatcaat acacaagaat
    25861 atatcgaaca acttgttaaa ccatttcaag agatggccat catagatgga aaagagttta
    25921 ttctccataa cgatgcaaca ttagaagtac caattgatga aaaaaaaatc catcaagttt
    25981 tggttatttt gctggataat gcattaaaat atacgaatcc agaagataag atcattttgg
    26041 attcatctgt taaccataaa gaatggctga ttcacgtaaa gaatactggc ccttctatca
    26101 gtgaagaaga tcaagcaagg atttttgatc gattttatcg ggaagatcaa tctcgggcga
    26161 aagagactgg cggatacggg cttggcttgg caattgcaaa acaggtaatc gaacagcatc
    26221 atggacagat ttctgtatcc aattatcttc cacaaggagt cgattttaaa gtccaattgc
    26281 cgttgaagcc taaaaaataa tgcttatccc taaaaaaggg ctgtgacaaa aatcttgtca
    26341 cagccctttt ttgttgcgaa taaacggtgt tccagaagta gcttcttcgg aaataagccg
    26401 aaatttcttt aagctgacca cttctgtcac aacctcttta gcttacgctt acgatttttt
    26461 attgcggtct tcaatgtgta catcaccgct tgtgtcaata tccaattctt ctcggctaac
    26521 atcttctgtc actttttcaa catcttcatg ttcttcttta tgaatcccaa cttcttcacg
    26581 aataactgta tgtttgctta catctacttg ctcttctttg attgggatag taatcgtgtc
    26641 atcttccaat ttttcgtctg ttccctgtga agattgatct gttactggtt tgcgttcgat
    26701 gacgatttct tcacgtttga ccggtacttc taccgtttca gtatcgttga ccacatgttt
    26761 gtggatgtcg acttctccag ttgtcacatc atgtgtattt acatctaatt tttcttcttt
    26821 tagttgaatt gtatcatcat ctagatttgg tttgcgatcg atgtcttcag tcttgcttgt
    26881 acccattgta tcagtctcgc caggtacgtc catcggatca gttcctggtg tcatattcaa
    26941 tggatccgtt gtattttgaa agcctgtcgt gccacctacg tccattggat ctgttccagt
    27001 gccagtttct aatccagtcc ccattgtgct tgctgggcta acagtatctt gtgtatccat
    27061 tgtatcttct gttgtttctg gctgacgata gccttttact gtgatgacaa attttccatc
    27121 agaaatatct cctctatatt gatataaagg atcattttct ggtgtagccg tctcagaatc
    27181 ataggtatca aaagaaaaag tatcttttat tttttcccat aaagaacggt cttcttcacc
    27241 atccatccga ttttcatctg tttcaacatc tataccagac aatccgtcaa atcctagtct
    27301 agatgctgct tcatcagtag tataaataac gatatcatct cgttcatacc cttcgttacg
    27361 caaccgttca attactgata atgcttcttc cctcgtacta tagcttccga tgaccgttaa
    27421 atttttctct tccatgtaaa ttcctcctag caaatagatt tatgattggt atattgttac
    27481 ttataaattt attctatagg agacgattgt tttctacaaa tatttagatt ggaatttgat
    27541 taaaa
//
LOCUS       DAZUJR010000034        27493 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.034, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000034 DAZUJR010000000
VERSION     DAZUJR010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27493
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.034"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(79..765)
                     /gene="gpmA"
                     /locus_tag="ACG804_001353"
     CDS             complement(79..765)
                     /gene="gpmA"
                     /locus_tag="ACG804_001353"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HFS4832294.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(937..1518)
                     /locus_tag="ACG804_001354"
     CDS             complement(937..1518)
                     /locus_tag="ACG804_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFS4832295.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(1651..2334)
                     /gene="rpiA"
                     /locus_tag="ACG804_001355"
     CDS             complement(1651..2334)
                     /gene="rpiA"
                     /locus_tag="ACG804_001355"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HFS4832296.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            2653..3066
                     /gene="rpsL"
                     /locus_tag="ACG804_001356"
     CDS             2653..3066
                     /gene="rpsL"
                     /locus_tag="ACG804_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HFS4832297.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            3150..3620
                     /gene="rpsG"
                     /locus_tag="ACG804_001357"
     CDS             3150..3620
                     /gene="rpsG"
                     /locus_tag="ACG804_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HFS4832298.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            3714..5801
                     /gene="fusA"
                     /locus_tag="ACG804_001358"
     CDS             3714..5801
                     /gene="fusA"
                     /locus_tag="ACG804_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HFS4832299.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            5973..7160
                     /gene="tuf"
                     /locus_tag="ACG804_001359"
     CDS             5973..7160
                     /gene="tuf"
                     /locus_tag="ACG804_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HFS4832300.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            7567..7875
                     /gene="rpsJ"
                     /locus_tag="ACG804_001360"
     CDS             7567..7875
                     /gene="rpsJ"
                     /locus_tag="ACG804_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HFS4832301.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            7906..8535
                     /gene="rplC"
                     /locus_tag="ACG804_001361"
     CDS             7906..8535
                     /gene="rplC"
                     /locus_tag="ACG804_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HFS4832302.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            8563..9186
                     /gene="rplD"
                     /locus_tag="ACG804_001362"
     CDS             8563..9186
                     /gene="rplD"
                     /locus_tag="ACG804_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HFS4832303.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            9186..9476
                     /gene="rplW"
                     /locus_tag="ACG804_001363"
     CDS             9186..9476
                     /gene="rplW"
                     /locus_tag="ACG804_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HFS4832304.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            9515..10348
                     /gene="rplB"
                     /locus_tag="ACG804_001364"
     CDS             9515..10348
                     /gene="rplB"
                     /locus_tag="ACG804_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HFS4832305.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            10391..10669
                     /gene="rpsS"
                     /locus_tag="ACG804_001365"
     CDS             10391..10669
                     /gene="rpsS"
                     /locus_tag="ACG804_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HFS4832306.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            10692..11039
                     /gene="rplV"
                     /locus_tag="ACG804_001366"
     CDS             10692..11039
                     /gene="rplV"
                     /locus_tag="ACG804_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HFS4832307.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            11053..11709
                     /gene="rpsC"
                     /locus_tag="ACG804_001367"
     CDS             11053..11709
                     /gene="rpsC"
                     /locus_tag="ACG804_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HFS4832308.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            11712..12146
                     /gene="rplP"
                     /locus_tag="ACG804_001368"
     CDS             11712..12146
                     /gene="rplP"
                     /locus_tag="ACG804_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011375443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HFS4832309.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            12136..12324
                     /gene="rpmC"
                     /locus_tag="ACG804_001369"
     CDS             12136..12324
                     /gene="rpmC"
                     /locus_tag="ACG804_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HFS4832310.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            12349..12615
                     /gene="rpsQ"
                     /locus_tag="ACG804_001370"
     CDS             12349..12615
                     /gene="rpsQ"
                     /locus_tag="ACG804_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HFS4832311.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            12673..13041
                     /gene="rplN"
                     /locus_tag="ACG804_001371"
     CDS             12673..13041
                     /gene="rplN"
                     /locus_tag="ACG804_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HFS4832312.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            13078..13386
                     /gene="rplX"
                     /locus_tag="ACG804_001372"
     CDS             13078..13386
                     /gene="rplX"
                     /locus_tag="ACG804_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HFS4832313.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            13414..13953
                     /gene="rplE"
                     /locus_tag="ACG804_001373"
     CDS             13414..13953
                     /gene="rplE"
                     /locus_tag="ACG804_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HFS4832314.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            13972..14157
                     /locus_tag="ACG804_001374"
     CDS             13972..14157
                     /locus_tag="ACG804_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HFS4832315.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            14193..14591
                     /gene="rpsH"
                     /locus_tag="ACG804_001375"
     CDS             14193..14591
                     /gene="rpsH"
                     /locus_tag="ACG804_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HFS4832316.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            14623..15159
                     /gene="rplF"
                     /locus_tag="ACG804_001376"
     CDS             14623..15159
                     /gene="rplF"
                     /locus_tag="ACG804_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HFS4832317.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            15320..15676
                     /gene="rplR"
                     /locus_tag="ACG804_001377"
     CDS             15320..15676
                     /gene="rplR"
                     /locus_tag="ACG804_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HFS4832318.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            15697..16197
                     /gene="rpsE"
                     /locus_tag="ACG804_001378"
     CDS             15697..16197
                     /gene="rpsE"
                     /locus_tag="ACG804_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HFS4832319.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            16212..16391
                     /gene="rpmD"
                     /locus_tag="ACG804_001379"
     CDS             16212..16391
                     /gene="rpmD"
                     /locus_tag="ACG804_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HFS4832320.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            16435..16875
                     /gene="rplO"
                     /locus_tag="ACG804_001380"
     CDS             16435..16875
                     /gene="rplO"
                     /locus_tag="ACG804_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HFS4832321.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            16875..18170
                     /gene="secY"
                     /locus_tag="ACG804_001381"
     CDS             16875..18170
                     /gene="secY"
                     /locus_tag="ACG804_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HFS4832322.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            18232..18879
                     /locus_tag="ACG804_001382"
     CDS             18232..18879
                     /locus_tag="ACG804_001382"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_function: GO:0019205 - nucleobase-containing compound
                     kinase activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HFS4832323.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            19070..19288
                     /gene="infA"
                     /locus_tag="ACG804_001383"
     CDS             19070..19288
                     /gene="infA"
                     /locus_tag="ACG804_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HFS4832324.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            19321..19437
                     /gene="rpmJ"
                     /locus_tag="ACG804_001384"
     CDS             19321..19437
                     /gene="rpmJ"
                     /locus_tag="ACG804_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HFS4832325.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            19455..19820
                     /gene="rpsM"
                     /locus_tag="ACG804_001385"
     CDS             19455..19820
                     /gene="rpsM"
                     /locus_tag="ACG804_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HFS4832326.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            19848..20237
                     /gene="rpsK"
                     /locus_tag="ACG804_001386"
     CDS             19848..20237
                     /gene="rpsK"
                     /locus_tag="ACG804_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HFS4832327.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            20317..21255
                     /locus_tag="ACG804_001387"
     CDS             20317..21255
                     /locus_tag="ACG804_001387"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HFS4832328.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            21283..21663
                     /gene="rplQ"
                     /locus_tag="ACG804_001388"
     CDS             21283..21663
                     /gene="rplQ"
                     /locus_tag="ACG804_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HFS4832329.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            21935..22774
                     /locus_tag="ACG804_001389"
     CDS             21935..22774
                     /locus_tag="ACG804_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HFS4832330.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            22750..23619
                     /locus_tag="ACG804_001390"
     CDS             22750..23619
                     /locus_tag="ACG804_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HFS4832331.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            23609..24406
                     /locus_tag="ACG804_001391"
     CDS             23609..24406
                     /locus_tag="ACG804_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HFS4832332.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            24609..25355
                     /gene="truA"
                     /locus_tag="ACG804_001392"
     CDS             24609..25355
                     /gene="truA"
                     /locus_tag="ACG804_001392"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HFS4832333.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKVRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            26019..26213
                     /locus_tag="ACG804_001393"
                     /pseudo
     CDS             26019..26213
                     /locus_tag="ACG804_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(26401..27177)
                     /locus_tag="ACG804_001394"
     CDS             complement(26401..27177)
                     /locus_tag="ACG804_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFS4832334.1"
                     /translation="MNIHHIRNATAILDYGGKKFLIDPMLAEKGTLPPFISKGPFPSP
                     RKDQMNPLVDLPMPVEDIINGIDAVIVTHLHLDHWDDIAKEVLPKEIKLFVQDENDAN
                     EIRLYGFKNVEVLREDTVFESIQLVKTKGKHGRGEILNYVGNVCGIVFKHSTEKTLYF
                     TGDTVWYEAVKQTIDQYNPEIIVANAGDNHFLVGESLIMGKDDLYELHKAIPDSTIIA
                     VHMEAVNHWGLSREELKSFNKEKGISEKVLVPEDGDNIFI"
     gene            27300..>27493
                     /locus_tag="ACG804_001395"
     CDS             27300..>27493
                     /locus_tag="ACG804_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HFS4832335.1"
                     /translation="MLDQTDINIIEELSKNSRITMKELGEKVHLTGPAVSARVTKLEE
                     SGVIENYTVKLNMEKLGFSI"
BASE COUNT         8932 a         5042 c         5819 g         7700 t
ORIGIN      
        1 agttggcagg agaaaaccgt ttatacgaaa aaagggactg tgacaaatcg tgtcacagtc
       61 ccttttttat agtgtttttt ataggtagta ttttttagca actgttaagt catcatttaa
      121 ttcataaaca agtggttgac ctgttggaat ttcaagatcc atgatgtctt cgtcagagat
      181 accttcgata tgtttagcta gggcgcgtaa tgagttacca tgtgcagcta ctaaaacagt
      241 tttgttgtct agtaatgctg gagcaatttc atcttgccag aatggcaaag cgcgttctaa
      301 tgtcactttc aagttttctc caccaggaat atcgcgtttg tctaacattg cgtaacgacg
      361 gtcatttgct gcagaacctt cgtcagtttc ttccattaat ggaggaagag tatcgtaaga
      421 acgacgccag atgtgcactt gttcgtcgcc gtatttttca gctgtttctt ttttgttcaa
      481 accttgtaat ttaccatagt gacgttcgtt taagcgccat gatttgattt gtggtaccca
      541 aagttgatct gaatattcta agatcaagtt acatgttttg attgcacgag ttaaaacaga
      601 agtgtaagca acatcaaatt cgattccagc ttctttgatt ttgcgtccgc cttcttttgc
      661 ttcttcgatt ccttctggtg ctagatttac atcagcccaa ccagtaaatt ggttcaatgc
      721 attccattca ctaagaccgt gacgagaaaa aactaatttt ggcatgttta gctctccttt
      781 taagataggt ttatatttct gaaattttca gttctgtttt attgtacaat tttttggaag
      841 agatttccat cgaaaaatta gataagattc tatgagaaaa caagtagaga atataaaaaa
      901 acgaacagtg cccacgcaac tgttcgtttt taggtattag atgcataatt gctcgatttc
      961 tttttcaggt aaattgatat atttataaca tgttccaact gaaacaccgc attttgaaga
     1021 aataaattgg atcgtttctt ttttttcata atagagacgt cggatttttt tgatcgtttt
     1081 tgcatcgatt tttggtcttc cgccgatttt tcctttttta cgagcttcat ctaatccaac
     1141 taatgtacgt tctttgatca atgcgcactc catgtttgct aggttttcca ttaattggaa
     1201 atagattttt cccatttcgc gcgtatcgat tccttcatca agactaatca agtgcagccc
     1261 gcgatctttg aataattgcg tgagttctgt taattgccgc gtagatttgc ctaatcgatg
     1321 aagttggcaa atgactagtg catcgccttg ttgcatgtca gcgatcactg actccaaatg
     1381 aacagcagta gaatcatttt gttccacttc atatgtctca tggaaaattt cttgacaacc
     1441 aaagtcagat aattgatcaa cctgagttgt taaatcaacg tcatttatgg ttgtgcgtgc
     1501 ataaccaata attttcatgg tgattccttt ctagcagtga ttttctaact ggatataaca
     1561 gtaaaaatgt agcataaagt acgtcaaaaa gatagttttt tcgcaaattt tccgctgtct
     1621 ttttttattg gatgatcaag cagtttttct ttatttacga cggattgcgt caagaatctc
     1681 aacgcctttt tctgagccga caactacttt agaaaccatg tttaggaaaa gcccatgttc
     1741 tactacccca acaagttcat ctaaataggt agctaagctt tctggctgtt cgatgacttc
     1801 tagatgcaga tcaatgatgt aatgaccacc atctgtggtt aagacttctc cgttttcgtc
     1861 tgtacgcaag acgggttgga atcttttttc ttcaaaaata tgaagtagct gttgggagcc
     1921 ataagggatc acttcaactg ggagtgggaa cttcccaagt ttatcgacta atttagaaga
     1981 atcaacgatc caaatcgttt cttttgagta cgtagcgact attttctcga aaagcaaagc
     2041 agcgccgccg cctttgatcc cttgaaaatc agcactgatt tcatcagcac cgtctattgt
     2101 caaatcgact acggggactt catcaatact ctttaacggt attcctaatt tttccgcttg
     2161 ttcttttgtc gcatttgaag tagtaactcc tgtgatacgt aaaccttctt cacgcatacg
     2221 gcgaccaatc tcttctacca tataataggc ggttgaaccg gtcccgagac ctacgatcat
     2281 cccgtccttt acgaatttcg cggcttcaat gccagctaat tgttttaaat tcatctttgc
     2341 gtccaccttt ttttagtttg agcatcgtgc tttcctcact attttagcgt gatttacggt
     2401 aaaaagatac cattcttttt tattccaata aagctttttc aaaaaaaatt gcatctcttg
     2461 ttgacatgtt ttttcattcg tgatattcta acaaaggtgc tttatctaca ggtttctgtg
     2521 aagaaacgtg ctgactgttt atcaaagcat atttgataag gatgcagaca ttgcatttat
     2581 tttttatcac aaaaaaagaa ccacctggat gtgtggaact agacgcaaat cgtgggaagg
     2641 aggaaacaag gaatgcctac aattaaccaa ttagtacgta aacctcgtaa atcaaaggtg
     2701 gaaaaatcta attcacctgc tttgaacaaa ggatataaca gctttaagaa aactcaaact
     2761 aacgtaaact cacctcaaaa acgtggggta gcaactcgtg tgggtacaat gacacctaaa
     2821 aaaccgaact cagctttacg taaatatgca cgtgttcgtt tgtcaaactt aattgaagtt
     2881 actgcttata tcccagggat tggtcataac ttacaagaac acagtgttgt attattacgc
     2941 ggtggtcgtg taaaagactt accaggggta cgttaccata tcgttcgcgg tgctttagat
     3001 actgctggtg ttaacgaccg taaacaaagc cgttctaaat acggaactaa aaaacctaaa
     3061 gcttaatttt aattattaaa caaatgaaac ttgcttctac tatatagaag taattactat
     3121 gaacaatatt tcggaaggag gagttacgga tgccacgtaa aggtcctgtt gcaaaacgtg
     3181 atgttttacc agatcctatt tataactcaa aattagtaac tcgcttgatc aaccgtgtaa
     3241 tggttgacgg aaaacgcggg attgcagcta acattatcta taatgccttt gacttgatca
     3301 aagaatctac aggtaacgat ccattagaag tgtttgaaca agcaatgaaa aacgttcaac
     3361 ctgttcttga agttaaagca cgtcgtgttg ggggttcaaa ctaccaagta ccagttgaag
     3421 ttcgccctga acgccgcgtt actctaggtc ttcgttgggt agtaaactac gctcgcttgc
     3481 gcggtgaaca cacaatggaa gaacgcttag caaaagaaat catggatgct gcaaacaaca
     3541 caggtgcttc tgttaaaaaa cgtgaagaca ctcataaaat ggctgatgcc aaccgtgcgt
     3601 ttgctcacta tcgctggtaa gattctctct gtttggtcgg cttttataag tcgacctcag
     3661 atagtgtcct tatttttagc aactagatag taaagagagg agaaacaagg agaatgacca
     3721 gagaattttc tttacaaaac actcgtaata tcggtatcat ggcccacatc gatgctggta
     3781 aaacgactgc tactgaacgt atcttgtact atactggtaa aatccataaa attggtgaaa
     3841 ctcatgaagg agcttcacaa atggactgga tggaacaaga acaagaacgt ggtattacga
     3901 tcacttctgc tgctactaca gcacaatgga agggtcaccg aatcaacatc atcgacacac
     3961 caggacacgt agacttcaca gttgaagttg aacgttcatt gcgtgtactt gatggtgctg
     4021 taactgttct tgatgcacaa tcaggtgttg aacctcaaac tgaaacagtt tggcgtcaag
     4081 caacaactta tggtgtacct cgtatcgtat ttgcaaacaa aatggacaag atcggtgctg
     4141 acttcttata ttcagtatca actttacatg accgtttgca agcaaacgct cacccaatcc
     4201 aattaccaat tggtgcggaa gacgacttca caggaattat cgaccttgta acaatgaagg
     4261 ctgaaatgta tacaaacgat cttggaacag agatcgaaga aacagaaatt cctgaagaat
     4321 accgcgaatt agctgaagaa tggcgcgaaa aattggttga agctgtagct gaaactgatg
     4381 aagaacttac tttgaaatac ttagaaggtg aagaaatcac tgaagctgag ttaaaagaag
     4441 gtatccgccg cgcaacagtt aacgtagaat tctacccagt actatgtggt tcagcattta
     4501 agaacaaagg ggttcaatta ctattggacg ctgttcttga ttacttgcca tcaccgttag
     4561 atatcccagc tatcaaaggg attgacccta aaactgatga agaagtagaa cgtcctgcag
     4621 acgacagcgc tcctttctca gctttagcat ttaaagttat gactgaccca ttcgtaggtc
     4681 gtttaacttt cttccgtgtg tactctggtg ttttacaatc aggttcatac gtacaaaacg
     4741 caacaaaagg caaacgtgaa cgtgttggtc gtatcctaca gatgcatgcc aactctcgtt
     4801 cagaaatctc tgaagtttac gctggagata tcgctgctgc tgttggtttg aaagacacaa
     4861 ctactgggga cacactatgt gatgaaaaga gtctagttat tcttgaatcc atggaattcc
     4921 cagaaccagt tatccaagtc gctattgaac ctaaatcaaa agctgaccaa gataaaatgg
     4981 gtgtggcttt acaaaaacta tctgaagaag atcctacttt ccgtgctgaa acaaacgtgg
     5041 aaacaggcga aacaatcatc gctggtatgg gtgaacttca cttagatatc atcgttgacc
     5101 gtatgcgtcg tgaattcaaa gttgaagcta acgtaggtgc gcctcaagta tcttaccgtg
     5161 aaactttccg tgctggcact caagccgaag gtaagtttgt acgtcagtct ggtggtaaag
     5221 gtcaatacgg tcacgtatgg attgaattta caccaaatga agaaggtgct ggtttcgaat
     5281 ttgaaaatgc gatcgtcggt ggggttgttc ctcgtgaata cattccagct gttgaaactg
     5341 gtttgaaaga tgctatggaa aatggtgtct tagctggcta tccattagta gatatcaaag
     5401 ctaaacttta cgatggttca taccatgatg tcgattcaaa tgaaactgcc ttccgtgttg
     5461 ctgcttctat ggcattacgt gcagcagcta agaaagctaa tccagtaatc cttgaaccaa
     5521 tcatggctgt agaagttgtt atccctgaag attatttagg tgatgttatg ggtcacgtaa
     5581 ctgctcgtcg tggacgtgtt gaaggtatgg aagctcgcgc tggcggccaa caagttgttc
     5641 gtgcgatggt tccacttgct gaaatgtttg gttatgctac aactcttcgt tctgctactc
     5701 aaggtcgtgg tacatttaca atgacatttg accactacga agatgtacca aaatcagtac
     5761 aagaagaaat cattaagaaa aacggcggaa aagctgaata atttcttaaa accggatagt
     5821 cctgcaaaga gattatccaa agagactata tttttaatat agtttcgtgt aaaataatta
     5881 tcgatgatat gggcatgtgg tgtaccttgt gtacatcata tacctatcag acaaataaaa
     5941 aatatattgt atttttagga ggacatttta aaatggcaaa agaaaaattt gaccgttcta
     6001 aaccacacgt taacattggt actatcggac acgttgacca tggtaaaact acattaacag
     6061 ctgcaatcac aactgtacta tctaagaaaa acggcggcca agctatggct tacgatcaaa
     6121 tcgatggtgc tccagaagaa cgcgaacgcg gaatcacaat ctcaacagct cacgttgagt
     6181 atgaaacaga tacacgccac tacgctcacg ttgactgccc aggacacgcg gattacgtta
     6241 aaaacatgat cactggtgct gctcaaatgg acggagctat cttggtagtt tctgctgctg
     6301 acggcccaat gcctcaaact cgtgaacaca tcctattgtc tcgtcaagtt ggtgttcctt
     6361 acatcgttgt attcttgaac aaagtagaca tggttgatga cgaagaatta ctagaattag
     6421 ttgaaatgga agttcgtgac ctattaacag aatacgaatt ccctggtgac gatgttcctg
     6481 tagttgctgg atcagctttg aaagctctag aaggcgacgc ttcatacgaa gaaaaaattc
     6541 ttgaattaat ggctgcagtt gacgaataca tcccaactcc agaacgtgac aacgacaaac
     6601 cattcatgat gccagttgaa gacgtgttct caattactgg acgtggtact gttgctacag
     6661 gtcgtgttga acgtggacaa gttcgcgttg gtgacgaagt tgaagttgtt ggtattgctg
     6721 aagaaacttc aaaaacaaca gttactggtg ttgaaatgtt ccgtaaattg ttagactacg
     6781 ctgaagctgg agacaacatt ggtgctttac tacgtggtgt tgcacgtgaa gacatccaac
     6841 gtggacaagt tttagctaaa ccaggtacaa tcacacctca tacaaaattc tctgcagaag
     6901 tatacgtgtt gacaaaagaa gaaggtggac gtcatactcc attcttcact aactaccgtc
     6961 cacaattcta cttccgtaca actgacgtaa caggtgttgt tgaattacca gaaggaactg
     7021 aaatggttat gcctggcgac aacgtaacaa tggaagttga attaatccac ccaatcgcta
     7081 tcgaaaacgg tactaaattc tcaatccgtg aaggcggacg tacagttggt gccggtgtcg
     7141 ttacagaaat caaagcttaa ttcacttaag ttttaaagta aagcaacatt tattcggacg
     7201 taatcgctcg gaacgaaggt cttaggatct ttgttccgag cttttttatt tattgcagga
     7261 tcaggaaaaa agacaggagt attataaata gaagaaacac gaaataaaag agtcagtatt
     7321 ttctaaatga aactttatga aaacaaaatg ttttttacaa gaaaaagcct tgctttgtga
     7381 gtttatatat attataatga caaaggtgcg tttactttag tgaattgcac agacgtaatc
     7441 agaatgattt cgtcggctaa gaaacgagag gttgcgacac gcccggacgc tttgccacga
     7501 acgagcgtga cggaaatttt cgtggagcta tgtctacttt tcaaaatagg cgaaggaggg
     7561 aacaagatgg caaaacaaaa aattcgtatc cgtttaaaag cgtatgaaca ccgtatttta
     7621 gatcaatcag cggataaaat cgtggaaact gcaaaaagaa ctggagctag cgtgtctggt
     7681 ccaattccat taccaactga acgcagtctt tacacaatca tccgtgcgac tcataaatac
     7741 aaagattcac gcgaacaatt cgaaatgcgt acacacaaac gtcttatcga cattgtgaac
     7801 ccaacaccaa aaactgttga tgctttgatg aagctagact taccatctgg tgtaaacatc
     7861 gaaatcaaat tataaaacta aaacaaaaat aatggaggtg tactcatgac caaaggaatc
     7921 ttagggaaaa aagtgggaat gacacaaatc ttcactgaat ctggtgaatt aattccagta
     7981 actgttgtag aagctactcc aaacgtagta ctacaagtga aaacaatgga aacggatggc
     8041 tacgaagcta ttcaagttgg ttaccaagat atgcgtgaag ttttatcaaa caaacctgcg
     8101 aaaggtcatg ttgcaaaagc aaacacggct cctaagcgct tcattcgtga attcaaaaat
     8161 gttgagctag gagaatatga agtaggaaaa gaaattacag tagatgtttt ccaagcagga
     8221 gacattattg atgtaacagg tactacgaaa ggtaaaggat tccaaggggt tatcaaacgc
     8281 cacggacaaa gccgcggacc aatggctcac ggttctcgtt accatcgtcg tcctgggtca
     8341 atgggtccag ttgcacctaa ccgtgtattt aaaaacaaac gtcttgctgg ccgtatgggt
     8401 ggcaaccgcg taactatcca aaacttggaa gttgtacgtg tcgatgcaga aagaaatgtt
     8461 atcttgatca aaggtaatgt tcctggagct aaaaaatctt taattactat caaatcagct
     8521 gtgaaagcta aataattgta ggaagaaagg aggaactaag gaatgccgaa tgtagcatta
     8581 ttcaaacaag atggaagcca aaacggtgaa atcacactta acgaagaaat cttcggaatt
     8641 gaacctaatg aaagtgttgt ttacgatgca atcgtaatgc aacgtgcgtc attaagacaa
     8701 ggaacacacg cggttaaaaa ccgtagcgct gttcgcggcg gcggacgtaa accatggcgt
     8761 caaaaaggaa caggtcgtgc acgtcaagga tctatccgct caccacaatg gcgtggaggt
     8821 ggcgtagtct ttggaccaac accacgttct tacagctaca aacttcctaa aaaagttcgt
     8881 cgtttagcaa tgaaatctgt attgtcagaa aaagttgctg aaaacaactt ggtagcaatc
     8941 gaaggcttga acttcgacgc accaaaaaca aaagaattca aacaagttct tgctaactta
     9001 tctatcgact ctaaagtatt ggttgttcta gaaaaaggta acgactttgc tgctttatca
     9061 gcacgtaact taccaaacgt ttctgtagta acttctgata atgtgagtgt gctagacgtt
     9121 gtatcaaata caaaagtgtt agcaacacaa actgctctta ctcaaattga ggaggtgctt
     9181 gcataatgaa cttactagac gtaatcaaac gcccagtgat cactgaaaaa tcaatgcttg
     9241 ccatggatga caagaaatac acttttgaag tggacactcg cgcaaacaaa actttagtaa
     9301 aacaagcggt agaagctgct tttgacgtta aagtcaaaaa cgtgaacatc gtgaacgtac
     9361 gtgcgaaatt caaacgtatg ggcaaatatg caggatatac aaaaaaacgt cgcaaagcga
     9421 tcgttacatt gactgaagat tcaaaagaaa tccaattatt cgaagctgct gaataagcac
     9481 taatagataa ctcattaaat taggagggaa aaacgtggcg attaaaaagt acaaacctac
     9541 ctcaaatggt cgtcgtaaca tgacaggttc tgattttgct gaaatcacaa catcaacacc
     9601 tgaaaaatca ttgttacaac cattgaaaaa ccatgctgga cgtaacaaca acggccgcat
     9661 cactgtacgt catcaaggtg gcggacacaa acgccaatat cgcgtgatcg acttcaaacg
     9721 taacaaagat aacgttgttg caactgttca aacgatcgaa tatgatccaa accgttcagc
     9781 taacatcgcg ttagtacact atgaagatgg agtgaaagct tacatcttag cacctaaagg
     9841 actagaagtg ggtatgaaac ttgtttcagg tccagaagca gatatcaaag tcggaaatgc
     9901 tcttccatta gaaaacattc cagttggtac tgttatccac aacattgaaa tgaaacctgg
     9961 taaaggtgga caattgatcc gttctgctgg tacaagtgct caagtacttg gtaaagaagg
    10021 caaatacgta ttgatccgct tgaactctgg tgaagttcgt atgatcttag ctgcatgccg
    10081 tgctacaatc ggttctgtag gtaacgaaca acacgaatta atcaacatcg gtaaagctgg
    10141 acgctctcgt tggatgcgta aacgcccaac tgtacgtggt agcgtaatga accctaatga
    10201 tcacccacac ggtggtggtg aaggtaaagc tcctatcgga cgtaaagcac cagtttctcc
    10261 ttggggtcaa ccagctcttg gttacaaaac tcgtaacaaa aaagctaaat cagacaaact
    10321 tattgttcgt cgtcgcaaaa ataaataatt actttgacca tgtgtcgcac attttgagag
    10381 gaggttcacc atgggtcgta gtttaaagaa aggacctttt gtcgatgagc atttaatgaa
    10441 aaaagttgaa gctcaagcag gggttgaaaa gaaaaaagtt atcaaaactt ggtcacgccg
    10501 ttcaacagtt ttcccaagtt ttgttggata taccatcgca gtttatgatg gacgtaaaca
    10561 tgtaccagtt tacatccaag aagacatggt aggacacaaa ttaggtgaat ttgcacctac
    10621 aagaacttat cgtggacatg ctgctgacga taagaaaacg aaacgctaat ttgaggggag
    10681 gataaatcca aatggcagaa caaatcacat cagctaaagc aactgcaaaa acagttcgca
    10741 cttcacctcg aaaagcccgt ttagtaattg accttatcag aggtaaaagt gtcgcagatg
    10801 caatttcaat cttgaaattc acaccaaaca aatctgctgg aatcattgaa aaagtattga
    10861 tgtcagcagt tgcgaatgca gaaaataact ttgacttaga tgttgaaaac ttggtagtaa
    10921 gcgaagcttt tgttaacgaa ggacctacaa tgaaacgttt ccgtcctcgt gcaaaaggat
    10981 cagcttctcc aatcaacaaa cgtacaagtc atatcacggt agtcgtatca gaaaaataag
    11041 gagggataat cagtgggtca aaaagtacat ccaattggaa tgcgtgtagg catcatccgc
    11101 gactgggatg ctaaatggta tgctgaaaaa gagtatgctg agttcttaca cgaagattta
    11161 agaatccgta aatttatttc aactaaactt gctgatgctg ctgtatcaac agttgaaatc
    11221 gaacgcgcaa caggtcgcgt aaacatttca attcacacag ctaaaccagg tatggttatt
    11281 ggtaaaggcg gttctgaagt cgaaagccta agaaaagaat taaacaaatt aactggtaaa
    11341 agaatccata tcaatatcgt ggaaatcaaa aaaccagatc tagatgcaaa attagtaggt
    11401 gaaggaatcg cacgtcaatt agaaaaccgt gttgctttcc gtcgcgctca aaaacaagcc
    11461 atccaacgct caatgcgtgc tggcgctcaa gggatcaaaa ctcaagtatc tggtcgtcta
    11521 aacggagcag atatcgctcg ttcagaagga tactcagaag gaactgttcc tcttcatact
    11581 ttacgtgcgg acattgatta cgcatgggaa gaagcagata caacatacgg aaaactagga
    11641 gttaaagtgt ggatctatcg tggagaaatt cttccaacta aaaaaaacac tgagaaagga
    11701 gggaaataat catgttagta cctaaacgtg taaaacaccg tcgtgaattc cgcggaaaaa
    11761 tgcgcgggga agctaaaggc ggaaaagaag tagcattcgg tgaatacggt ttgcaagctg
    11821 ttgattcaca ttggatcaca aaccgccaaa tcgaagctgc tcgtatcgca atgactcgtt
    11881 acatgaaacg tggtgggaaa gtatggatta aaattttccc tcacaaatct tatactgcca
    11941 aagcaattgg ggtacgtatg ggttctggta aaggggcacc tgaaggatgg gttgcaccag
    12001 taaaacgtgg taaaatcatg tttgaaatcg caggcgttcc tgaagaagta gctcgtgaag
    12061 cgttacgtct agcttctcac aaattaccaa tgaaaactaa gatcgtaaaa cgtgaggaaa
    12121 tgggtggtga atcgaatgaa ggttaaagaa atcagagaat taaccactgc cgaaatgctt
    12181 gatcaagaaa aacaattaaa agaagaattg tttaatctta gattccaatt agcaacaggt
    12241 caattagaaa acactgcacg tattaaagaa gtacgtaaat cgattgcacg catcaaaact
    12301 gtgttgcgtg aacaagctaa gtaattatgg aaggaggcca ttaagcgtat gactgaagga
    12361 agaaatcaac gcaaagttta tcaaggtcgc gtggtttcag acaaaatgga taaaacaatt
    12421 accgttgctg tcgaaacaaa gaaaaaccac cctatctatg gcaaacgcat gaactattct
    12481 aagaaataca aagtgcatga tgaaaacaac acagcaaaag ttggcgacat cgtgagaatt
    12541 atggaaactc gtccattatc agctacaaaa cgtttccgtt tgttggaagt agtcgaagaa
    12601 gcagttatta tctaataaca cgagattttc ctatatagat tgaatgcaaa atctgaaagg
    12661 aggatacaca acgtgatcca agcagaaagt cgtttaaaag tcgctgataa ctcaggcgca
    12721 cgtgaaattt tgacgatcaa agtccttggt ggatctggtc gtaaaactgc taacatcggt
    12781 gatgtgatcg ttgctacggt taaacaagca acgccaggtg gggttgtcaa aaaaggtgac
    12841 gtcgttaaag ccgttatcgt tcgaacaaaa tcaggagctc gtcgtacaga cggttcatat
    12901 attaaatttg atgaaaatgc tgcagtgatt attcgtgatg ataaaagccc tcgtggaaca
    12961 cgtatctttg ggccagttgc acgtgaacta cgtgaaaaca acttcatgaa gatcgtttca
    13021 ctagcaccag aagttttata atcttgagac acttatcaaa ggaggtgcga aacagttatg
    13081 tttgttaaaa aaggcgataa agttaaagtt atcactggaa aagacaaaaa caaagaaggc
    13141 gttgtactag cagcgttccc gaaaaaagat aaagttattg tcgaaggtgt aaatgtcgtt
    13201 aaaaaacacc aaaaaccttc tcaagctgct cctcaaggtg gaattgttga gatggaagcg
    13261 ccaattcatg tttctaacgt gatggtggtt gactctactg gtgtagctgg ccgagttggc
    13321 tacaaagaag tagacggcaa aaaagtccgt gtttctaaaa aaaccggtga agttttagat
    13381 aaataaaagt ttaaggaagg agggtcttac tgaatgaacc gcctaaaaga aaaatatctt
    13441 aaagaagtaa ctccatcatt gatggaaaaa tttaactata gctctgttat gcaaacacct
    13501 aaagttgaaa aaatcgtcat caacatgggt gttggtgatg cggtatcaaa cgctaaaaac
    13561 ttagataaag cagttgaaga attaactttg atcactggtc aaaaaccaat gattacaaaa
    13621 gctaaaaaat caatcgctgg attccgttta cgtgaaggaa tgccaattgg tgcaaaagtt
    13681 acattgcgcg gagaaagaat gtacgaattc ttagacaaat tggtttctgt ttcactacca
    13741 cgtgtacgtg acttccatgg tgtaagtaaa aaagcctttg acggtcgtgg aaactatact
    13801 ttaggtatta aagaacaatt gatcttccca gaagtagatt atgatttagt agataaagta
    13861 cgtggtatgg acatcgttat tgtaacaaca gcaaactctg atgaagaatc tcgtgagttg
    13921 ttgacacaat taggcatgcc attccaaaaa taattaaagg aggcgaacta cgtggctaaa
    13981 aaatcaatga ttgctaaaaa caaacgtcct gcaaaatttt caacacaagc ttatactcgt
    14041 tgcgaacgtt gcggacgtcc acattcagtt tatcgtaagt tccatctttg ccgtatttgc
    14101 ttccgcgaac ttgcctataa aggtcaaatt cccggcgtga agaaagctag ctggtaaaaa
    14161 gtaaattcgc ataagaagga ggtaaaagat caatggtcat gacagatcca attgcagatt
    14221 ttctaactcg tatccgtaac gcaaacatgg ttaaacatga gtctttagaa gtacctgcat
    14281 caaaaattaa acgtgacatc gctgaaatct tgaaacgtga aggtttcgtt cgtgatgttg
    14341 aatacatcga agatgacaaa caaggcgtga tccgtgtttt cctaaaattt ggtaaaaacg
    14401 gcgaacgtgt tatcacaaac ttaaaacgta tctctaaacc aggtttgcgt gcttatgtca
    14461 aagctgacga agtaccaaaa gtattgaacg gtttaggtat cgcaatcatt tcgacttctg
    14521 aaggtgttgt cactgataaa gaagctcgtg aaaaaaatat cggcggcgaa gttatcgctt
    14581 acgtatggta atcaagtaga atctacaagg aggtgtcttt aagtgagccg tatcggaaat
    14641 aaagtcgttg ttatccctga aggagtaaca gttactcaag acggaaacaa cgttacagtt
    14701 aaaggaccaa aaggtgaatt gactcgtact ttttcagcag atatcaaaat gaatatcgaa
    14761 ggaaacgaag taactttcac tcgtccaaac gacagtaaag aaatgaaaac aattcatgga
    14821 acaactcgtg cgaacttcaa caacatggtt gtaggtgtca gcgaaggttt ccaaaaagcg
    14881 ttagaactaa tcggggttgg gtaccgtgca caattacaag gatcaaaact tgtattgaac
    14941 gttggttact cacatccagt agaaatcaca ccaccagctg gagtaactgt tgaagtacca
    15001 gctaacacac aagtaattgt taaaggtgcg aacaaagaag aagttggcga attagctgca
    15061 aacattcgtg gaactcgtcc tccagaacct tataaaggta aaggtattcg ttatgttggc
    15121 gaatatgtac gccgtaaaga aggtaaaact ggtaaataat cgtttagaaa aattgcatag
    15181 aagccagcag caggaaaaag gcatttggct gaagtttacc ttcaaaaaaa tacattttta
    15241 cttgtgccgc agcttctatt tttcgaaacg tatttactgc ttgaaatagt agtacaataa
    15301 aaataaagag gtgacaattg tgattacaaa accagataag aacaaaacac gtcaaaagag
    15361 acatcgtcgt gtacgtaaca atatctctgg tactgctgag cgcccacgct tgaacgtttt
    15421 tcgttctaac aaaaacatct acgctcaaat tattgatgac gtagcgggtg taacgctagc
    15481 aagtgcctct accttggata aagaaatttc aggtggaaca aaaacagaag cagcacaagc
    15541 tgtcggtaaa ctagttgctg aacgtgcagc tgaaaaaggc attaaagtag tagtctttga
    15601 ccgtggtgga tacctttacc atggccgtgt gcaagcttta gctgaagctg ctcgcgaaaa
    15661 tggactagaa ttttagaaga aggaggaata ccattcatgg tttatatcga tccaaaacat
    15721 ttggaattag aagaccgcgt tgttgcaatt aaccgtgtaa caaaagttgt taaaggtgga
    15781 cgtcgtctac gttttgctgc tttagttgtt gtcggtgaca aaaacggaca cgtagggttt
    15841 ggtacaggta aagctcaaga agttcctgaa gcaatccgta aagcaattga agatgcgaag
    15901 aaaaacttag ttgaagtacc tatggttggt tcaacaatcc cacacgaagt aatcggtgct
    15961 tttagtggtg gtagaatcct aatgaaacct gctgtagaag gttctggggt tgctgctggt
    16021 ggaccagttc gtgccgtatt agaattagct ggggtagcag atatcacttc taaatcttta
    16081 ggctcaaata caccaatcaa cgttgttcgc gcaacagttg aaggtttgaa acaattgaaa
    16141 cgtgcagaag aagttgcaga acttcgcggc aaatcagttg aagaattaat cggataagga
    16201 ggacaacaat aatggctgaa ttaaaagtta ctttaaaacg cagtattatc ggacgtcctc
    16261 aaaaccaacg cgatacagtt aaagcgttag gtcttacaaa gattaacagt tcagtggtta
    16321 agccttctaa tgaagcaatt aaaggcatga tcaatactgt ttctcaccta gtggacgttg
    16381 aagaaattta atttagaaaa atcataacta gaacattaag gaggtgccaa acctatgaaa
    16441 cttcatgaat taaaacctgc tgaaggttca cgccaagtac gtaaccgtgt tggtcgtggt
    16501 acttcatctg gtaacggaaa aactgccgga cgcggacaaa aaggacaaaa agctcgttca
    16561 ggcggcggtg tgcgtttagg atttgaaggg ggacaaacac cattgttccg tcgtttacca
    16621 aaacgaggat tcacaaacgt gaaccgtaaa gactatgcag tcattaatct tgatgtattg
    16681 aaccgctttg aagacggagc tgaagtaact cctgttgctt tagttgaagc tggaatcgtg
    16741 aaaaacgaaa aagctggaat caaagtatta gctaatgggg aactaaacaa gaaattaact
    16801 gtgaaagcag caaaattctc taaagcagct caagaagcaa ttgaagcggc tggtggatca
    16861 atcgaggtga tctaatgttt agactattaa aagatgcttt taaagtaaaa gacattagat
    16921 cgaaaatcct atttactgta tttgtgttgt ttgtatttcg cctaggtgca catattactg
    16981 taccaggcgt aaatgctgct tcattgcaaa acctttcttc tttgccattt ttcaacatgt
    17041 tgaacttggt aagtggtagt gcgatgcaaa acttttccat tttctcaatg ggggtttcac
    17101 catacattac tgcttctatc gtcattcagc ttcttcaaat ggacatcgtg cctcgatttg
    17161 ttgaatggtc gaaacaaggg gaagttggtc gtaaaaaact gaatcaagcg actcgatatc
    17221 tgacattagt attggcattt atccaatctg tcggtatcac tgctggattc aatcaatacg
    17281 ctcaattagg tttcgtgaat aatcctaacg tagcaactta cgtaacgatc ggtttgattc
    17341 taacagccgg tacgatgttt gttacttggc taggagaaca gatcacagaa aaaggtatcg
    17401 gaaatggcgt atcaatgatc atttttgcag gtatcatttc tagattgcct gaaagtatca
    17461 gagaaattta tgaagattac tttataaata ttgatccttc agacatatgg aaatctgcta
    17521 tttttgtggc cattttacta gtagcggtct tgttgatcgt gacattcgta acatttttcc
    17581 aacaagctga acgcaagatc ccgatccaat atacgaaacg cgtagctggc gcgcctacaa
    17641 gcagctatct gccgttgaaa gtaaatgcag ctggagttat tccagttatc tttgctagtt
    17701 cgtttattgc tacgccaaat gctgttttac aagcattgag cggtagattc ggttctgaaa
    17761 actggtacaa agtgatgatg gagatcttta actataatac agcacctggt gctacgattt
    17821 atacgattct gatcgttgcc ttcactttct tctacgcctt tgttcaagta aaccctgaga
    17881 aattagcgga aaacttgcaa aagcaaggaa gttatatacc aagcgtacgc cctggtaagg
    17941 ggactgaaga gtatgtctca agattactga tgcgtttaag tacagttggt gcagtcttcc
    18001 ttggtttagt ggcattgctt ccaatcattg ctcaaatggt ttgggatctt ccacaatcaa
    18061 tcggattagg cggtacaagc ttactgatcg ttatcggtgt agctttagaa actgcgaaac
    18121 agttagaagg cttaatgctg aaacgtaaat atgttggatt cattgagtaa gaaagcgtgt
    18181 tgaggtttcc cctcaacaca cgttctcaca catttattag gagggaaaac aatgaacctc
    18241 attttaatgg ggctgccagg cgcaggtaaa ggaacacaag ctgaaaaaat cattgatgct
    18301 tatggtattc cgcacatctc aacaggagat atgttccgcg cagcgatgca aaacgaaaca
    18361 gctcttggcc tggaagcaaa gtcttatatg gataaaggtg cattagttcc tgatgaagta
    18421 acaaatggaa tcgtgaaaga gcgactagct gaaccagata cagagaaagg cttcttatta
    18481 gatggctttc cacgtacgct agatcaagca aaagctctgg acgcaatgct aaaagatttg
    18541 aataaaaaaa ttgatgctgt catcgatatc catgttggtg aagaaatctt ggtcgaacgt
    18601 ctagccggcc gatttatctg cagcaattgt ggagcaactt accataaaat tttcaaccct
    18661 acaaaagttg aagacacatg tgatcgttgc ggtgggcatg aattctatca aagagaagat
    18721 gataaacctg agacggttaa aaatcgtctg gctatcaaca tcaaaaatag tgaaccaatc
    18781 ttggcttatt ataaagaaca aggtttgcta aacactattg atggtgctcg tgaaatcgat
    18841 gctgtatttg cagatgtaca aaaaatcatt gaaaaatagc acgattgccc gtagccgact
    18901 tgcattatgc agttactctt gtcaagttca ataaattatg atagaatatg tcagtccgac
    18961 ttctagagaa tcctctagat gatccatttt gagaattttg aggtgggaac tgcagtttcc
    19021 gccattttat cgtgtgaaaa tgcgaaacaa gtacaaggag gtactgtgcg tggcaaaaga
    19081 agatatgatt gaagtcgaag gtacagtcgt cgaaactttg ccgaatgcaa tgtttaaagt
    19141 tgaactagaa aacggacacc aagttcttgc tactgtttca ggtaaaattc gtatgcatta
    19201 catccgtatc ttacctggtg acaaagtaac ggttgaattg tctccatacg atcttaaccg
    19261 tggccgtatt acttatcgct ttaaataatt gtactccgta aaactacagg aggtattatc
    19321 atgaaagtaa gaccatcagt aaaaccaatg tgcgaacatt gtaaagtaat tcgtcgtaaa
    19381 ggacgcgtta tggtgatttg cccagcaaat ccaaaacata aacaacgtca aggataattg
    19441 gaggtgctat aaatatggct cgtattgcag gagtagatat tcctcgtgat aaacgtgtag
    19501 tagtttcact tacttatatc tatggtattg gtaacactac tgctaaaaag atcttagctg
    19561 atgctggtgt atctgaagat gttcgcgttc gtgaattaac gaatgaacaa acagatgcta
    19621 tccgtgcaga agtagataaa ttaaaagttg aaggggatct tcgtcgtgaa gtgaacttga
    19681 acatcaaacg tttgatggaa atcggttctt accgtggaat ccgtcatcgc cgtggattgc
    19741 ctgttcgtgg acaaaacacg aaaaacaatg cacgtactcg taaaggccca gctcgcgcta
    19801 tcgctggcaa gaaaaaataa ttcttaagtg aaggaggtta aaacttcatg gcagcaaaaa
    19861 aagtgaatcg taaacgccgt gtgaagaaga atatagaagc aggtattgca catatccatt
    19921 ctacattcaa taacactatc atcatgatca ctgatactca cggaaatgca ttagcgtggt
    19981 catcagctgg ttcattaggt ttcaaaggaa gcaaaaaatc aactcctttt gccgctcaaa
    20041 tggcagcaga aactgctaca aaagcagcaa tggaacacgg attaaagact gttgaagtaa
    20101 cagttaaagg acctggttct ggacgtgaag cagcaattcg ttcattacaa gctacaggtt
    20161 tagaagtgac tgcaattcgt gacgtgactc cagttcctca taatggtgcc cgccctccaa
    20221 aacgccgtcg tgtttaatga gtgccgctca ttttgagttt tatcagtaac gtcattgaac
    20281 aagacacttt tcgttttgaa aggggtaaag ataagaatga ttgagttcga aaaaccaaga
    20341 atcgcaaaaa ttgatgaaga aaaagattat ggcaagttca tcgttgaacc tcttgaaaga
    20401 gggtatggga ctactttagg gaattcccta cgtcgtattt tattatcttc tttgccaggt
    20461 gctgccatca ctaatattca aatcgatggt gtactgcatg aattctctac catcaaaggt
    20521 gttagagaag acgtcactca aatcatcttg aacattaaag gcttagcgct gaaaatgtat
    20581 ggccaagaag aaaaaaccct tgaaatcgat attaccggac ctgctacagt aactgctggc
    20641 gatattatcg ttgatagtga tgtagaaatt cttaacaaag atatgtacat ctgtagtgtc
    20701 tctgaaggag ctacgttcca tgctcgctta acagtgaaac ctggacgtgg ttatgttcaa
    20761 gcagatgaaa ataaaaaaga agatatgcca attggcgttc ttccagtcga ttcaatctac
    20821 acacctgttc gtcgtgtgaa ctatcaagtt gagaacacac gtgttggaca ccgtgaagat
    20881 tttgataaat tgacgatgga gatttggaca gatggttcaa ttgaaccgtt ggaagcaatg
    20941 agtttgtctg cgaaaatcat gactgaacat ttggatattt ttgtgaactt aactgatgaa
    21001 gcaaaaaatg ctgaaatcat ggtcgaaaaa gaagaaacac aaaaagaaaa aatgttggaa
    21061 atgacgatcg aagagttaga cttgtctgtt cgctcttaca attgtttgaa acgtgcagga
    21121 atcaatactg tacaagaact tacaaataaa tctgagcctg aaatgatcaa agtccgtaac
    21181 ttaggacgta aatcattaga agaagttaaa gcaaaattgc acgacttagg tttaggttta
    21241 cgtaaagaag attaaaacct tttacgaagg agggaaacca acgtgagtta tcgtaaacta
    21301 ggacgcacat ctagccaacg taaagcgatg ttgcgtgatt taacaactga tttattaatc
    21361 aacgaacgta ttgtgactac tgaagctcgt gcgaaagaag ttcgctcaac tgcagaaaaa
    21421 atgatcactt taggtaaacg cggagatttg catgcacgtc gtcaagctgc ggctttcgta
    21481 cgtaatgaag ttgccagcgt gcgtgaagaa aatgaggaca tcgtcattga atcagcttta
    21541 caaaaactgt tcaacgatat tgcacctcgt tacgcagaac gtcaaggcgg atacacacgc
    21601 attttgaaga cagaaccaag acgcggtgat ggtgcaccaa tggttgtctt agaacttgtc
    21661 taaaatcaca ctaataacat cactttatag atgattcttt tagagtgtta tgatgttgga
    21721 agatattttt ccgagtctag ctcagcgctg ctcctcaagc gaatatcgct tggggagtaa
    21781 gcactcatca taaagtgttt ttttatacct tcaattacct gtcatgacag atatgtttga
    21841 aggcataaaa aaacatttta agcgagaaat aattgaaaat tttgtctttt tttgatagtg
    21901 ttagtaggaa ctttaggatg aagaaggagt aatcatggag ccaattattg aattagaaaa
    21961 gataaattat aaataccagc cagatgatct tcgccccgca ttgaaagatg tctcctttac
    22021 aattgataaa ggtgagtgga tcgctattat tggacacaat ggttcaggaa aatcgacact
    22081 tgccaaaacg atcaatggat tgcttctgcc agaatcaggg atcgtgaaag tgggaaatca
    22141 aatattggat gaagaaaata tttggacgat ccgacagatg gttggaatgg tttttcaaaa
    22201 tccagacaat cagtttgttg gttcgacagt agaagatgac gttgcttttg gtcttgaaaa
    22261 tcaagggatt cccagagaag aaatgctagt gcgtgtgaaa gatgcacttg agaaagttag
    22321 aatggctgag tttgcttcac gcgagcctgc tcgtttatca ggagggcaaa aacaacgtgt
    22381 tgccattgcc ggcgtggttg ccttacgacc tgatatcatt attttagatg aagcaaccag
    22441 tatgctagat ccagaaggtc gtgaagaagt gatctctacg atcaagaaga tcaaagaaga
    22501 aagtcaattg accgttatat ctatcactca tgatattgat gaagcagcta atgccaatcg
    22561 gatactagtg atgagacaag gcgaacttgt ccgtgaaggt acaccaaaag aaattttttc
    22621 tgctggtcct gaactgatcg acttaggtct agatctacca tttcctgaaa aactgaagag
    22681 cgcactgaaa gaacgtgggg ttgatgtgcc cagtgaatat atgacagaag aaaggatggt
    22741 ggattggtta tggacatccg ttttgaacaa gtagacttca cttatcagcc gaatacacca
    22801 tttgaacaaa gagccttatt tgacatcaat atgacgatca aagaaaacag ttatactgca
    22861 ttagtagggc ataccggaag cgggaaatca accttacttc agcatttgaa tgcgcttgtt
    22921 aagccaacaa gcggtacagt ccatattgga gaacgagata ttcagccgga tacggataat
    22981 aagaatttaa agcccatccg aaaaaaagtt ggcatcgtct ttcagtttcc agaagcacag
    23041 ctattcgaag aaacggtagc aaaagacatt gctttcggtc ctaaaaactt tggtgtcagc
    23101 gaagaagaag cactagtcct agcaaaagaa acattagaac aagttgggct ggatgaaagc
    23161 tatttggaac gttcgccatt tgaactttca ggagggcaaa tgcgtagagt agcaatcgct
    23221 ggtgtgcttg ccatgaggcc ggaagtactt gtattggatg aaccaacggc aggacttgat
    23281 ccccagggta gaaaagaaat gatggagatg ttttggcgtc ttcataagga acagcagatc
    23341 actattgtat tagttacgca tttaatggat gatgtagcca attttgcaga ttatgtctat
    23401 gtgttggaaa agggacgaat cgttaatagc ggggagccgc aagaggtctt tcaaaacatt
    23461 gaatggctaa aagaaaaaca actaggcgta cctactgcca ccgagtttgc agaagaatta
    23521 atggctaaag ggatgaactt tgctaccttg cctttgacag ctgaagaatt agcagacgct
    23581 atcgtccatt atgctggagg aaatgcccat gatgaataaa ttgatatttg gtcgttatat
    23641 gcctggagat tccttgatcc atcgattgga tccccgagct aaattattag ccagttttta
    23701 ttttatcgga atcatttttt tagcaaataa ttgggaaacg taccttttgt tggcattttt
    23761 cacattactt tctgtcttct tgtcaaaagt agatttgaaa ttttttatcc gaggcattcg
    23821 cccattgatc tggctaatcc tcttcactgt agctttgcag gtcttgttta caagtggcgg
    23881 agaaacttat tggagttggg gtgttttcca tatcactgaa tttggtgtga tgaacggcct
    23941 ctttattttc tgtcgattcg tgttgatcat ttttatgtcg actctactca cgcttactac
    24001 accgcctttg gaattatcgg atgcgattga gtacttgctt cgtccattga aagccgtacg
    24061 gttcccagtc cacgaaattt cattgatgct gtcgattgct cttcgttttg tgcctacatt
    24121 gatggacgaa acagaaaaga tcatgaacgc tcagcgcgct cgcggtgttg attttggtga
    24181 aggaaaccta gttcagaaaa tgaaagcagt cattcctttg ctgattcctt tatttgtcag
    24241 cagcttcaac cgtgcggaag atcttgcgac tgctatggaa gcaagaggct acaaaggtgg
    24301 ggaaggaaga acgaaatatc gtgtattgca ttggcataat agagacacga tggttatcat
    24361 tgcttttgta ttattaactg tgctactgat ctttttgaga ggataaacgt tcagtgggcc
    24421 gctatctatt cttttcttgc tgatctgttt gcaagaaagg atgcgagcag tgtatgacaa
    24481 gaaatattag ggtctgtggc agactaaggt cacaggcctc tttcttttat ctgaaaagaa
    24541 agaacgaaaa aattttataa aaaaatcatt attccagata accttttagg aacaaaggag
    24601 agaaaaacat ggtacgttac aaagcaatca ttgcatacga cggaacaaat tttaatggat
    24661 tccaaaaaca gccaaatggg cgtactgttc aagaagaagt agaaaaaaca ttacaaaaaa
    24721 tggcaaatgg aaaagaaatc acggtctttg gttcgggaag gacagatgcc ggagtacatg
    24781 cgattgggca agtaatccat tttgattatc cagaggagcg tccgttagaa cgaatgcgtt
    24841 tcgcgctaga tacccagtca ccagaggata ttgctgtaag acaagtagaa attgtttcag
    24901 aagacttcca cgcaagatat ttggtcaaag aaaagacgta tcaatttcga gtggatatag
    24961 ggaaaccacg cagtcctttt cgacgccatt atgcaagtta ttttccttac cctcttgatt
    25021 tggaaaaaat tcagcgggcg cttcctgatt tattagggac tcacgatttc acctcttttt
    25081 gtgcatcagg aagctcgata gaggataaag tacgtacgat ctacgaggct aagatggagg
    25141 taaatgaaac aaaagacgaa ttgttgttta catttagggg aaatggcttc ttgtataaga
    25201 tgatacggat cttagtagga acgcttttga aaattggcaa tggccgattg cctgaagata
    25261 gtatcccaga tattattgcg aaaaaagatc gtaatgcagc aggacctaca gcacatcctg
    25321 aaggacttta tttgtatgaa gtgaaatatg aataagaggt tgtgacagaa gtggtcagct
    25381 tcaagaaata agaaggaatt tacgaaaatt acttctcaaa attttgcaaa atttcggctt
    25441 attttcgaag gagctacttc tggaacaccg tgaatcagag gttgtgaaaa agctgccctg
    25501 catcaagtaa taagaacaac caaacaaaaa tagctcgtca tatttttcgt ttggttgggc
    25561 ttattaccgc agatgcaagc ttttgaacac cgtttaagga agaggttgtg aaatcagcgt
    25621 tttgacctga gtattagaga aacaaacgga aaaatagttc ctcatatttt gccgtttgtt
    25681 gagctaatac cgaaggtcag ctgattgaac accgtttaag aaagaggtcg tgagcctgtc
    25741 atttaactct gagtcacaag taacaatttc aaaaaacagc ttctcatctt tgatgaatat
    25801 cgtgacttgt ggacgaggcg ttgataagtg aatcatcttt ttgttaccta ttttttctgt
    25861 aaccaaaaaa cgatggaacg ttgttttgat tgcccttaat gaggacagtc ggaacaggtt
    25921 tgtcattttt atatttaaat ggcacaaatt tttctaatta tttgtcattt agcgctgaaa
    25981 atttttgcta tttatctaaa aaagtgataa ctacttaaga tgaagcagaa tatttacgcc
    26041 atacggcata caaccgcgaa aaatataaaa aaaagaaaac gattgaacgc gtttttgcag
    26101 tcgcaaagga aaagcatgga atgcgctaca tcaagtatcg agacttggaa aacaatcagg
    26161 tgtatacgct gattgttttt gctgcaatga atctgaaaaa gttgtccact tggcagttgg
    26221 aacatatgtc ttcatatctt ttattataca aaaatagcaa aagcaccagt ctacactctt
    26281 agtaaagagg aaactgatcc ttttgtctac attcttaaag tacttaaact aagtacttta
    26341 ttttactctt taggattgat acagtagcat ctatcccttt attaataatc ttttattttt
    26401 ttaaataaag atgttgtctc catcttcagg cactaaaact ttttcggaaa ttcctttttc
    26461 tttattgaaa gactttaatt cttctcttga cagtccccaa tggtttacag cttccatatg
    26521 aacggcaata attgtggaat ctggtattgc tttatgcaat tcatataaat cgtctttccc
    26581 cataataaga gattctccaa ctaaaaaatg attatctcca gcatttgcta ctatgatttc
    26641 tggattatac tgatcaatag tttgtttaac agcttcatac caaactgtat ctcctgtaaa
    26701 gtatagtgtc ttctcagtcg aatgtttgaa aacaataccg caaacattac ctacataatt
    26761 caagatttct cctctgccat gtttgccttt tgttttaacc aattgtatag attcaaaaac
    26821 tgtgtcttct cgtagtacct ccacattttt aaaaccatat agtcgaattt cattcgcatc
    26881 attttcatct tgcacaaata attttatttc tttaggtagg acctctttcg ctatatcgtc
    26941 ccaatgatct agatgtaaat gtgttacaat aacagcatca ataccgttga taatatcttc
    27001 gactggcatt ggcaaatcaa ctagaggatt catttgatct tttcttggtg atggaaaagg
    27061 acctttcgaa ataaatggtg gaagtgttcc tttttccgct aacattggat caattaaaaa
    27121 ttttttacct ccatagtcta agatagctgt tgcattacga atgtgatgta tattcataaa
    27181 cgttgtctcc tttttgttga tatgaaatat ttttagtata attcaattcc atacaataaa
    27241 taaaccgaac aaaaaaagtc ttttactatt tttacttaat ttatgaaagg ttgtttacca
    27301 tgttagacca aacagatata aatatcattg aggaactatc aaaaaatagt cgaatcacaa
    27361 tgaaagaact tggagaaaaa gtacatttga ctggacccgc tgtctcggcg agagtgacaa
    27421 aactagagga aagtggagtt attgaaaatt atacagtaaa attaaatatg gaaaagctag
    27481 ggttttcgat tca
//
LOCUS       DAZUJR010000035        26161 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.035, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000035 DAZUJR010000000
VERSION     DAZUJR010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26161)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26161)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26161
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.035"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(62..1093)
                     /gene="queA"
                     /locus_tag="ACG804_001396"
     CDS             complement(62..1093)
                     /gene="queA"
                     /locus_tag="ACG804_001396"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HFS4832336.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            1286..2461
                     /locus_tag="ACG804_001397"
     CDS             1286..2461
                     /locus_tag="ACG804_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015837 - amine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HFS4832337.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            2465..3106
                     /locus_tag="ACG804_001398"
     CDS             2465..3106
                     /locus_tag="ACG804_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4832338.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            3103..4020
                     /locus_tag="ACG804_001399"
     CDS             3103..4020
                     /locus_tag="ACG804_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HFS4832339.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            4017..4688
                     /locus_tag="ACG804_001400"
     CDS             4017..4688
                     /locus_tag="ACG804_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4832340.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(5229..5717)
                     /locus_tag="ACG804_001401"
     CDS             complement(5229..5717)
                     /locus_tag="ACG804_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HFS4832341.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(5918..6184)
                     /locus_tag="ACG804_001402"
     CDS             complement(5918..6184)
                     /locus_tag="ACG804_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFS4832342.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(6184..6447)
                     /locus_tag="ACG804_001403"
     CDS             complement(6184..6447)
                     /locus_tag="ACG804_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFS4832343.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            6968..7108
                     /locus_tag="ACG804_001404"
                     /pseudo
     CDS             6968..7108
                     /locus_tag="ACG804_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            complement(7250..9073)
                     /locus_tag="ACG804_001405"
     CDS             complement(7250..9073)
                     /locus_tag="ACG804_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFS4832344.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(9671..12376)
                     /locus_tag="ACG804_001406"
     CDS             complement(9671..12376)
                     /locus_tag="ACG804_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HFS4832345.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(12682..13629)
                     /locus_tag="ACG804_001407"
     CDS             complement(12682..13629)
                     /locus_tag="ACG804_001407"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HFS4832346.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            13819..14088
                     /gene="rpsN"
                     /locus_tag="ACG804_001408"
     CDS             13819..14088
                     /gene="rpsN"
                     /locus_tag="ACG804_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFS4832347.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(14264..14626)
                     /locus_tag="ACG804_001409"
     CDS             complement(14264..14626)
                     /locus_tag="ACG804_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFS4832348.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(14637..15758)
                     /gene="alr"
                     /locus_tag="ACG804_001410"
     CDS             complement(14637..15758)
                     /gene="alr"
                     /locus_tag="ACG804_001410"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HFS4832349.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(15774..16124)
                     /gene="acpS"
                     /locus_tag="ACG804_001411"
     CDS             complement(15774..16124)
                     /gene="acpS"
                     /locus_tag="ACG804_001411"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HFS4832350.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(16254..17765)
                     /locus_tag="ACG804_001412"
     CDS             complement(16254..17765)
                     /locus_tag="ACG804_001412"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFS4832351.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(18087..19439)
                     /gene="murF"
                     /locus_tag="ACG804_001413"
     CDS             complement(18087..19439)
                     /gene="murF"
                     /locus_tag="ACG804_001413"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HFS4832352.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYLEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(19592..20668)
                     /locus_tag="ACG804_001414"
     CDS             complement(19592..20668)
                     /locus_tag="ACG804_001414"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HFS4832353.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            20864..22609
                     /locus_tag="ACG804_001415"
     CDS             20864..22609
                     /locus_tag="ACG804_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/UbiB family protein"
                     /protein_id="HFS4832354.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(22889..23326)
                     /locus_tag="ACG804_001416"
     CDS             complement(22889..23326)
                     /locus_tag="ACG804_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HFS4832355.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(23310..24683)
                     /locus_tag="ACG804_001417"
     CDS             complement(23310..24683)
                     /locus_tag="ACG804_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832356.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(25005..25493)
                     /locus_tag="ACG804_001418"
     CDS             complement(25005..25493)
                     /locus_tag="ACG804_001418"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4832357.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(25515..26117)
                     /locus_tag="ACG804_001419"
     CDS             complement(25515..26117)
                     /locus_tag="ACG804_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFS4832358.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         7504 a         5561 c         4837 g         8259 t
ORIGIN      
        1 ctttgtcata aaatctttgt aaagcttttt tgttattcaa aactagcggc ttttcataac
       61 cttatttcac gaacatcgca tctccaaaac taaagaaacg atagcgctct tcaatcgcat
      121 gctggtaagc agataaagtc aattctcttc ctgcaaaggc actaactaac atgactaaag
      181 tcgattttgg caaatggaaa ttagttgaga aagcttctac cactttgaat tcatagccag
      241 gcgtaatgaa aatatcagtc catccgctgt ctgctttgat ttctccatta aatttcgttc
      301 caatcgtttc taatgttcga attgaagttg ttccgacagc cacgattttc ccgccatttt
      361 tacgtacttg gttcaatcgc tcagccgctt cttccgtcaa acggtagaat tcactatgca
      421 tatggtgttc ttcaatttta tctacgctga caggtcggaa tgtacctaac cctacatgta
      481 gtgtcagata gactaattca acaccctttg cttcgatctc atcaagtaat tctttcgtaa
      541 aatgcaatcc agctgttggc gctgcagcag aaccattttc tttcgcatag acagtttgat
      601 agcgatctgg gtcttccaga cgttctttga tatatggagg caatggcatt tctcccaatg
      661 attcaagaat ctctagaaaa attccttcat actcaaagtc aatgatccgt ccgccgtgtt
      721 ccaattcttc tttcactact gcttgcaatc tgccatcacc aaaagagatt cttgtcccaa
      781 ctttggcacg tttcgcaggt ttgatcaatg tctcccacgt atctccttgt gtattcgtta
      841 gaagaaggac ttctaaatgc gcaccagtat ctggtttttc tccatataaa cgagcaggca
      901 gaactcgtgt attattcata actagcgcat caccaggctg taactcttca atgatttcat
      961 ggaaatgttt atcttccatc tctccagttt tccgatccaa aacaagtaaa cgagaatgat
     1021 cgcggtcttt taatggtgtt tgtgcgatta attcttccgg caagtcaaaa tcaaaatctt
     1081 ctgttgttaa catatcgtca ctcactttct atcatgtgct tcatcattct atcatgtttt
     1141 tcgttctgtt ggcaaaatca gcactttttc acttctattt tttgttttcc taaataaaaa
     1201 aactacccta tttgtatttt ttcattgttt taggcatact agtaatagat agttcttcat
     1261 tgaaaataga aaaagaggtg gcaccatgat tgaatttcaa aatgtgtcaa aaatttataa
     1321 aggtggaaaa gtcgctgtag aggacgtcaa tctttcattt gaaaagggtg agttcatttg
     1381 ttttatcggt acgagcggaa gcggaaaaac gacgacgatg cggatgatca accgaatgac
     1441 tgatccaaca caagggaaaa ttttgattga tggaaaatcc atccaagaaa ttgatccagt
     1501 ggaattgcga cgtcagatcg gctatgttat ccaaagtatt ggattgatgc ctcacatgac
     1561 gatccgtgaa aatatcactc ttgtccaaaa attgttgaaa gtcagtcaag aagaacggaa
     1621 taaaacagct gaaaaaatga ttgatcttgt ggaattgccc cgtgagatgt tagatcgcta
     1681 cccacatgaa ttatctggtg gtcagcagca gcgtattgga gtcgttcgtg cccttgcagc
     1741 gaatcaagat atcatcttga tggacgagcc attcggtgcg cttgatccaa tcactcgtga
     1801 ttccttgcaa gaccttgtca aagatttaca agagcgtttg ggaaaaacga tcgtatttgt
     1861 aacccatgac atggatgaag cgattaaact agcaagccgt atcgccatca tgagtgaagg
     1921 ccgtgtgatc caatttgata caccagaaaa tattttacgt catcctgcaa acgatttcgt
     1981 agaagagttg attggagaag atcgcctact acaagccaag ccaaatgcga caagagtcgg
     2041 cgaagttatg ctaaatacag caatcacgat tacaccggaa aaatcattac aagaagcaat
     2101 caaactgatg agggaaaaac gtgtagatac gttgttagtt accgataatt cgaatgtatt
     2161 aaaaggattt atcgatgtag aaacgttgaa taaaaaacga ggaaaagtat ccagtgtcgg
     2221 cgacattttg aataaacatg ttttttacgt aaaagaatcc gcctatcttc gtgatacctt
     2281 gcaacgcatt ttaaaacgcg ggctgaaata cgtgccggtc gttgatgaac agaacaaagt
     2341 cgtaggtatc ctgactcgtg catcattagt ggatatcgtc tacgatgtga tttggggaga
     2401 agatcccgca actactgatg ttgcagagtc agctactcct gaagaatcta aggaggtctg
     2461 acctatgcag cagttttttc atcagcacgg ttcagaaatt ctctcaaaag gttttgaaca
     2521 tctttatatt tcaggacttg ctttgatcat tggtatcatc attgctgtac cgcttggtgt
     2581 cttactgaca cgttttccaa aagctgccac gattgtgatt ggcttaacca gtgccttgca
     2641 gacaatccct tctcttgctt tattggcatt gatgatcccg ctatttggcg taggtaaatt
     2701 acctgcgatt atcgcactct ttatttattc attattgccg attttacgta atacgtacat
     2761 tgggatgaaa aatgtcgatt ggaattatcg ggatgtggca aaaggcatgg ggatgactga
     2821 gttccaatcc attttttccg ttgaattgcc cattgctatg ccaacgatca tggctggtat
     2881 tcgtttagct gccgtttacg tgattgcatg ggctacactt gcctcttata tcggcgctgg
     2941 tggtttaggc gatttgattt ttagtggact gaataattac caaccagatc tcattttggc
     3001 aggtacgatc cctgtaacaa ttttagcact attggctgat tggcttctag gtctcttgga
     3061 acaccggctg acaccgatcg cacttagaga ggagaatgaa gaatgaaacg tatactaaaa
     3121 atgaccatgg ttcttttctc tcttcttata cttgcgagtt gttccttccc tggtcttgcc
     3181 agcaatacag atgaagacac catttcgatc acaggtggaa tcacttcaga agcacagatc
     3241 ttagcaagtc tagttgccgg aatggttgaa cattatacag ataaaaatac cgcaatcatc
     3301 aacaatctgg ctactacaac tatcaaccat caagcgatga tgaacggaga tgcttcaatt
     3361 tcagcggctc gctacacagg aacagattta acgactacat tgaaccttcc tcctgaaaaa
     3421 gatccgaaaa aagcgtttgc taccgtgaaa gatgaatttg agaaaagata cggtcaaacg
     3481 tggttcccgt cctatggttt tgaaaatacg tatgtctttc ttgttcgaaa agacaccgca
     3541 caaaaatacc atctatctaa agtcagcgat ctgaaaaatg tagcggatga attagtagct
     3601 ggtgtagata cttcttggat caatcgtaaa ggagacggtt atgacggctt ccaagaaact
     3661 tatggcttct ccttcaattc gatattacct atgcagattg gacttgttta tgacgcagtc
     3721 gaagcaggaa aaatggatat tgttcttggc tactctacgg atggacggat cgccagttat
     3781 gatctagtca tgttggaaga tgatcgtcaa ttcttcccac catatgatgc tgctccagtt
     3841 gtagacaaca agatattagc tgatacgcct catttaaaag aagccttaaa taagttaggt
     3901 cataccatca gtacggaaaa aatgcaggaa ttgaactacg aagcagataa taatctagtg
     3961 gaaccatcag tagtagcaca acgtttctta caagaaaacc actattttga agggaagtga
     4021 agcaattgga taaaatgaat gtctttcaac aatttttcta ttatttccag gaaaatggct
     4081 cctatatctt tgcacaattt atccgtcact tcctgatttc tatctatggt gtcctctttg
     4141 cagcagttgt cgggattccg gttgggatca tgatttctag gagacgtaaa ttagcaaact
     4201 gggtgattcg tttggcgaat atcatccaga cgatcccttc tctagccatg atctccattt
     4261 taatcattgg attaggcctg ggagtcaatg tcgtgattgt tactgtattt ttgtattccc
     4321 tcttaccgat catcaagaat acgtataccg ggatgatcca agtagacaaa aacatccttg
     4381 atgtcggcaa aggcatgggg atgactgcta gacaacgact attcatggta gagttaccac
     4441 tctctgtttc tgttatcatg gcaggcataa gaaacgcgtt agttgttgcc atcgggataa
     4501 ccgcgatcgg tgcattcgtc ggtgctggtg gtcttggaga tatcattatc cgaggaacca
     4561 atgcaacaga gggcacatcg attattttag caggtgcatt gccaactgca ttaatggcga
     4621 tcatcacgga ctggctttta ggtattttgg aaagacggct agatccagcc agccgtacat
     4681 cacgctgatg ttattgtaaa aaacaaaagc ttctgcgacc atttgttggt cgcaaaggct
     4741 tttttagttc tgtcattttt aaggcaataa tccactctga ttcttccctc cttatgggca
     4801 aagagttgct tttcttagct atttatccat tccgtatact ccaacttcat actgccaacg
     4861 ggttcatatc tgcatccacc gactaagttt ttttcttatc cgctaaggca ttttgccaat
     4921 ccattttccc atcactcgtc atggaattca taccacatga tctctaaata ctcgtctgct
     4981 tgttctttga attgggcatc aattcttaca tcctttggcg tggctttcat ttaagccttt
     5041 tccatcagtc ctcgattgtt cgatgccttc agctgcatca tcaaaactgg tgactgccgt
     5101 atcggtaact tcgatcatct tttatacaat caggaacttg ccatcctcat ccttggctaa
     5161 aaacatatct agccattcca gcttctcgcc atgggaggtt tgcggttcct aaaaccggta
     5221 cacgattctt atggactgca tccgtcgcaa ctagacttgg cgatacgatg atccttcacc
     5281 agaagagcac ccccgtaaac caattgatcg atatattgcc aataagaaaa gacattggcg
     5341 taaaagatat cgatccctcg tgatgcattg ccgttgatac tgctattcat ggccgaaagc
     5401 gccacgactt taacttcttc cgtttgagtg acattcatgt tcggcaatgt cgctttggat
     5461 acccgctctg ctaaaggaac gacactggta ttgtatttcg tatctgtatc ttttccaaaa
     5521 gaccatgcca acgaatcctc tgggaaccaa taagacgact ccggttgatt gtccattgct
     5581 tttttcaaca tacttttggc tgtttctcga taaacgacat ttccaattgt cttcgcctca
     5641 ctttggcgat aatcgatggt cgttgccact gccaacacta acaacgatgc tccaatttta
     5701 ctgattttcc ttgtcacact tcttcctcct tgttttacat aaacccgtca acattccatt
     5761 cctaaactca aacaatgacc cttcaaaggt ggagatatag gaacaaatta aagaaatcat
     5821 gcaataaatc caagaaggtt ggttttagaa caaaaaaaga gtctcctttt tggggagact
     5881 ctttgttaac tatctaaaaa ggttggctct tctcacttca ctcataatgt gtccaggcag
     5941 aataaatttc tacaacttta ttttcctcat caactttgta aaccactcga tgctgtctat
     6001 tcagcctgcg tgagtatctg ccttcatgtg taggtctcag cttttcaaaa gactgcgtgg
     6061 gcatatatgg atcttccttc aatgtctgaa tcacttcttc aaattgtttc tttaaattcg
     6121 tttgcttgat ttttcttaaa tccactttcg cagagttttt gattgcgact gtatagttac
     6181 tcatcaaaga gcttcccaat caatatcatc gatattcgta aagctactgt cgtctttttc
     6241 gcggtctcgt actttatcta aagtacctgt ttgctcaaga aaaagggttt cttgaatcgc
     6301 tctccagtct tccagcccaa tcaatacagc attgtttcca ctacgatcac taataatctc
     6361 gatttcagta tgattttcat ttacctcttt caataactga taaaaatttt tacgagcagt
     6421 gctaggattc atcgttgtat tagccattgt ctctcctcct ttttctgata taattatagc
     6481 gtacttgatt aagtacgtca aaaaaataca ataaagcact taaattcagc aaacttttcc
     6541 tcttttttac atagagaaaa agaccccttt ttagggagga tctttgtcca cgctcacttc
     6601 ttactccttt acgactagcg gtagccaaac gtaaagtaat tggtaacaac gtatcatctt
     6661 tagcaaaggt cgaatccaaa gcctgtgagt ctatgcaaca acaccaatac acgaaggttc
     6721 ctcgttgcag tgtgacttga ttgatatctt gaataacctg aggatacgca cgaaagattt
     6781 gtaacggtta ttcaaaactg attttggccg tcaagtcttc tactgcctca aaaatgattg
     6841 cctctttcgt ctcctgtcat tcatgttcac tatcgatttg atacttgctt agaccgttgg
     6901 gtttgtgaat caccaattaa aaatggcact gagttatggt aacaaaaaat ggtcacttga
     6961 cgaggctgag attcctactt atgaagacac atggcactta agagtcgagg taaaggaaga
     7021 agctgaaaat ataggaggct gtacattatt tggcaaagga ttcggaaatt atgatcaaga
     7081 catcaaaatc aaaatgtttt acagctaaat aggaagaata ataacatttc atacgctgtt
     7141 cccatcttta atggcttata gagggcacct ttagctgaga ataagacaaa acagaccctc
     7201 tagcttcaat taagagctag agggtctgtt tttgatttta aaacttggtt tatttcttca
     7261 aatggtagct ataggtgctg acaacgatat tttcacgcca agacaatcgc aatcttaacc
     7321 gcaaacttgt ttggttatgg agaatattct gccagcgtct gtttggtaca aattgaggaa
     7381 tcaacacagt agttgtatag ttttgtttcg ctgcattttt acttacgata tctacataac
     7441 ggataattgg attttcaatc gagcgataag aagagtggac gattgaaaaa cggacatctg
     7501 ggaaatgctt tttaaattct gcttcgattt ctttttcttt ttcgacatct tcgtctagcg
     7561 aaacatgcat cgcaacgaca taatcaccga tcgaacgtgc gtaattcaac gcaccgatat
     7621 ttacccgtgt cacattcccg actaatacaa gaacggtatt cccgtcataa tcatgtagtt
     7681 ttgcatcatt ttctaaacga agctgttctg ctactttttt ataatgatca tggatcttat
     7741 aaaaaatgaa cataacgatt ggcataatga tgaagaaagg ccaaatgtcc cctaaccgat
     7801 agacaaacaa aatcgcaatg attgcatatg agatgaacgc acccgtaata ttggcaatcg
     7861 atttgcttaa ccatcttttt ccttcttttt tccatttgac gaccatccct gtttgagata
     7921 aagcaaatgg aatgaacacg ccgatagagt ataacggaat caagcgttct gttgagccat
     7981 ggaaaataaa cagcaatacg atcgaaccta gcgctagtgt gataatccca ttggaatagc
     8041 ctagtcgatc cccacgatct tgatacatgt gaggcatgaa tttatctttt gccagattgt
     8101 atgcaagaac tggaaaagca gaaaaaccgg tgttagcagc aactgctaaa atcagcgctg
     8161 tagcaaattg aaggacgtaa tacaaaatac catgtccaaa gacagcttta ccaatttgag
     8221 acaaaacagt gacttctttt tcaggaacga tcccatacca atagttgata aatgtgatcc
     8281 ccacgaagaa gaaacctaag atcaatgcca tcatcgtcaa tgtagcagcg gcattttttg
     8341 ctcttggctt cttaaagaat ggtacagcat tactaatcgc ctccacccca gttaaagagg
     8401 aagaaccaga agaaaatgct cgtaaaatca aagcgataga aacacccggc acagccgctc
     8461 ctggaagtgc agtagcttgc aatggcacag cacctgtcac gatattatat aaaccaacaa
     8521 cgatcagtaa cgagatcaca aggataaatg tgtacaccgg aaataatagg aacgatgcag
     8581 attccctcag cccacgaaga ttcagcatca tcagtagcaa aacgattgtc acagaaatag
     8641 cgacttgatg accgtagagt gctggcaccg ctgatgtgat cgcttcagca cctgctgaga
     8701 cagatactgc tactgtcaac atgtagtcga tcaataaaga gccaccggaa atcaagccag
     8761 cattctttcc aagattctca ctgctgacga catatgctcc cccgccatga ggataagcat
     8821 ggatgatttg acgatatgat agcgttaatg aaatcaataa aataataaca aaagcggcaa
     8881 tgggtagcga ataccagatg gctgcagcag acaaagcgac taaaacgaca acgatttgtt
     8941 ccgtaccata tgcaatagat gataacgcat cagacgacaa taatgccaaa gcagcaaatc
     9001 gggttaattt gtgctcatca ttttcagcag attttaaagg cttacctact aacaaccttt
     9061 ttaagtaatc caatttctaa actcctttac acacaatttt acttcaagtt ttatagtcga
     9121 aaatttatag taaacaagat gttatagtac gctcactgac cttaaaagtc aataaacttt
     9181 aagaaaataa ttggaaaaaa acagaaaaat atcaagcgct ttttcaaacg ctttaataca
     9241 gcaaaaatct aacatttttt tatgggcttt ttctttgaat tctataataa aaggatagaa
     9301 cttgacttag aaaatcaagt tctatccttt ttgatatctt aacttttgga agagagatgt
     9361 aaggctgctt tctacccatc attcttacta ctcgaagcat agcgcagttg tcacaacctc
     9421 ttgataaacg gtgtttaaaa gcttgcatct gcggtaataa gcccaaccaa attaaaaaca
     9481 taagaagctg tttttatttg gtcgttctta ttacttgatg cagagcagct tttttacaac
     9541 ctcttggtac acggtgttca atcagctgac cctcggtatt agctcaaaaa aacggcaaaa
     9601 tatgaggaac tatttttcca tttttttctc taatactcag gtcaaaacac tgatttcaca
     9661 acctcttttt ttaatgaaaa atatggctct catgcgccgc ttctttgaat ttcgtcattt
     9721 tttcttcgat gaacggatag attgccgttc ctacgattcc aaagacaaca aacaaaccga
     9781 tcatgatcca gattgctttc gtagcatttg gccaataaat tcctcctgca gattcccgta
     9841 acaagtttac cgcatgagta aatggcaaga acggattgat catttggaag aatttccctg
     9901 agacttggat cggatagttc ccgcctccgc cagagatcga cagtactaag atgataatag
     9961 cgatcccttt accgacatta tcgaataatg cagccaagac atagacgatc atcatgaacg
    10021 ctaaggcgat caagacagca aatgacacgc tgtagaccgg attttggaca tctactccta
    10081 gtaagaaaat attccctaat gtaacgatca agctttgcgc aatcgccatt gtcaaaaatg
    10141 tcagcatacg agcaacgaat tgttctcgtt tcgtaaaatt gtttcggtct ttctttccta
    10201 aatagtattc tgtcgtagca acacttgaaa gaagaacagc gccgacccac agacatagtg
    10261 cagtataaaa cggggtgcta gctgaaccgt tatttgcgat tggataaagc gcattggttt
    10321 gtagctcaac aggttgtgta aagaagtcac tttcttttgt tgcgtctagt ttcaataatt
    10381 tgatgacttc gcctagatcg acttcttgtt cgccttttcg gatcgcgtct gctgcttttt
    10441 ggataccagc tttgatattt ggccagtcat tgttgatcaa gtccgcagca gcgttcacag
    10501 ctgtttcgac ttctggcatt ttttcattta ctgttgtcaa tgtaccggtg atttcatttt
    10561 ttagtgctgg ccaatcattt tggataaaat cagcggccaa tcctaatttt tgctgaatga
    10621 tcggtaattc attgttgtat aggtctgccc cttcattgat gccattgacg atggtatcca
    10681 tatttccatt cagcattgta ttggcatcat ggatttcttg tccaattgca ggcatttctt
    10741 tttgatattt ttctaaaatt gccactgcat tcgttacagt tgctttcgtt gagctgagaa
    10801 gcgaatcaaa gtcgatctgg tccgctttgc tcagtgcgcc ttgtgcagtc ccaatcgtat
    10861 cgatgacttg gtctagtaga gaagtgacag tggaactgat ttgacctgta ttgataccag
    10921 caatgatgcc attgatatta ttaacaacgg catcaatttg atctagcaat tcatcaatag
    10981 ccttcgtgtc ttcattttga acagctgtgt tcaaagcaga taggcggttt tgcagattgc
    11041 ttagcaaggg ttttaattga tttagctgat caataattgg ctgtaatttc gtatttccag
    11101 cacttgtttg caatttagtc aggaactcga ccagtttatc gattgcattt tgttgttgag
    11161 atattccgtc aataaagccg ttcaatacat tgctgatgtt tttcttttca tcatcagtca
    11221 gcttaccatc ttcaatagct gttcttacag tatctattaa cgaacctgtc gttgttgcca
    11281 cttgtccaat tgacttcaat gtaacatcta cactgtttgt gatgcttggt atcgcatctt
    11341 tcagctgaga ggcacctgat tttgtttggt ttgctagatc acttgcctga ttttctaaat
    11401 ttttcacatc tggcaagata tcttgtactt gttggatgat cgtcaagcct tgttttgctt
    11461 catcgattcc ttggttcatt gtctcttgga tcgaagcaaa atcgccgtcg atctctgcta
    11521 gttgcttacc ggcattttgg atctctggga ttttttcttg caaatcaagg atgatttttg
    11581 cttgatcttt caactcaggc attttgtcat tcaatgcaac gactttttca cccatctcat
    11641 ctactttagg gatgtaatcc acgaattcat ttgctttatt cagtttttcc ttgatttcag
    11701 gtagttgact ttgtaattcg aggacttgtt ttgtgtagcc gtcgatcgtg tccaaatttt
    11761 catctgttga taaaatcata tctttaactt tattgatact tactaggttc gtatcgatgt
    11821 cgtaacctat ctcattgaat actttcaata aagtcgaact ggctgttttg ataaattcat
    11881 ttgtgatttg cgattggatc gaacttgctc ctttatcggt gattttcggt gcaatcgcat
    11941 tgattttttc atttaccgta tattcgattt ttggtttctt gatatcacca ctagtaaaac
    12001 tcagcagatc ttctgagaaa tcctttggca agtaaatacc tgcgtaatac tttccggaac
    12061 ggactccgtc ttctaattgt tcttttgaat caacgaattg ccatcctaat tgtttatttt
    12121 tatgaagcga ttcgatgact tgctccccaa tggccacttc tttaccttga aactctgctg
    12181 gcttgtctgc actgtaaaca gcaattggca gctctccagt atttccatat ggatcccata
    12241 atgctttgat gttaaaccac gcatatagcg aagggatgat catgatcgcg atgatcagaa
    12301 gtgttgcaat cgggtttttg aaaatccgtt tccagtcaag caaatataat cgaagcgtat
    12361 ttttgattga ctgcatagtt ctcccccttc ttcttttttc agctgaatta ctttaccatg
    12421 tatttcatac ttttttcaat cggctttttt caaaaaagtc gaatttttgg acatatcacg
    12481 gcaattgtct cattgtaatc tcttacatat tgagaaataa ttaaggatta cagcctttac
    12541 tttatcatga aataaaaggg aaagataatt ttatgccaaa gtttttatct attatacgta
    12601 tacgcaaaaa agctaaaaca ttttttgtct ttgcccctac aaaaatgttt cagctttttt
    12661 cgttttttat tcctgtattt cttatttttc gaatgacagg atgattttcc cagcaggagg
    12721 atgtccttca actagctgat gtgcttggat gacatgctta agtgaagcag acagattcat
    12781 tgaaataaaa acatgaaagg ctcctttttg gtaggctttg attatgccag caaaggcttc
    12841 tgcatctaga tattcctttc ttggaacaaa cgattcataa aagccttcct ttttttgccg
    12901 caaatctaga tctgggaggt catttaatgc aacatacctg ccgcctggtt tcatgatctg
    12961 gatgccggtt tctcctttga tacttccttt cgtcgcatcg attacaaggt ctgcctgatc
    13021 agcaaattgc agacctggat ttgttttatc ataagcagca aatgctgaag ctcctaattt
    13081 ttttaccttt tcctcatttt tactggatgc actggttaag attcggattc ccttttcatg
    13141 gagaagctgg atcagacttg acccgaccgc acctgatgct cctagtatca ttacagtatc
    13201 tgtcggctgg atttccgtca aatggttgat tagattataa gccgtaattc ctggcgtgac
    13261 cattccggct gcttcttccc aactcatttt atctggaatt tttgctactt ttgctgatgg
    13321 caacacgact tcttctccgt aagtcccgcc gactgcatgg acagctactc gatcacctac
    13381 atgaacagtt gtgacatctg aaccaatctc tgtcacaata ccagcgccat cattacctgg
    13441 tacataaggg aatttcaatg ttcgtatctc tttcatttct cctaaacgca aggcaacatc
    13501 ataaggattc acactgaatg cttttatttc tacacgaaca tgtccagaac cgacttctct
    13561 gggatgagca tcgatttctt caaaaacatc ttgtgcttct ccgtaaccgt taattgcaaa
    13621 tcttcgcatg gtcaccatct ccctttttct ttaagtttac gtttatgcct ttattttgac
    13681 aaaaaaaatg tcttttcgtt ttggcgcatg attcaaaaca aaatagttgt cttttttcgc
    13741 gtaacgtgtt aaattattta tctaaaagcg taaagattac gatttacgct aataaaaaat
    13801 aattggagga atttgttgat ggctaaaaaa tcaaagattg ccaaagcaaa aaaacagcaa
    13861 gaaacgattg aacgctatgc tgctttacgc caggaattaa aagcgcaaaa agattacgaa
    13921 ggcttgcgta aacttccttt agatgctcgt ccagaacgat tgaaaaatcg tgatttaatc
    13981 gatggacgcc ctcgcggata catgcgtaaa ttcgggatgt cccgtataaa attccgtgaa
    14041 ttagcacata aaggtttgat tccaggagta aaaaaagcca gctggtaatc caagtctggc
    14101 tgtaatgtaa aggaggaggg cgcatggacc actccttgga tcatcaaaaa agatacgttc
    14161 gcttcttcta gcagaaatgc tggtactaga agcagacgta tcttttttta cgcacagctg
    14221 gtcctttttt atatgtaaag gctgcatggt tacttcgcta tatttattta gtaacaggag
    14281 tcagtgcttc gatacccaca ctaattttca atgctcggtc aacttctgcc ataatgggtc
    14341 gatccaaatg gcagaccttt tctttcaatc ttgatttatc gatcgttctg atctgctcca
    14401 acaggataac ggagtctctt tctattcctg ttccagtagc tttgatccca atgtgagtcg
    14461 gaagcttagg tttagccatt tttgccgtta tggccgcaac aatgatcgtc gggctaaaat
    14521 ggttacctag attattttga ataaccaaaa ctgggcgtgt tccgccttgc tccgatccca
    14581 cgactggaga aagatcagca aaataaatat ctcctctttt taccatagga tcctccttat
    14641 tcttgatatt ctcttggtat ccgctgtcct aatccgcaag ccacttcata gtggatcgta
    14701 cctaattgat ctgctatatc ctgcatagtg atttctttgt ctgcattttt gccgataagc
    14761 gtcacttttg ttccgacagg aaattcttga ggcaatcgga tcatcagttg atccatacat
    14821 acacgcccaa tcgtttcaca gtagttccct tctaccaata gagaaaaacc ctgcatcttt
    14881 cgtggccagc catctgcata accgatcggt atcgttccga tccactctgc ttcaggagtg
    14941 atatatgttt ctccatagcc gattccttca cctgctggga gttttttgac ttgaatcaat
    15001 tcagaaacca gctcaagtgc tggctgcaat ggataaactt ccggtagtgc gtgcccagag
    15061 ggattaagtc cgtacattgc tactccataa cgaatcatat tgccgattgt ttcatcatgc
    15121 cataaagccg ttgcactatt gctgacatgt acatatcgag gaagttcggg aagttttttc
    15181 agcacttcta taaagcgttc tttttgcaga ttccaatatg tatcatctgc ctgatctgct
    15241 gtagaaaaat gggtaaataa accttcccat tctaatacac gactttcttt gatgaatgca
    15301 gctgcctctt ttacttcttc aggtgtacaa aatccgatac gacccatccc agtgtctgct
    15361 tttagatgaa tcgaaagagg cgtctctagc ttacttttct ctaaaacagc agctgctgct
    15421 tgcaaccatt cccgtgtacc tgcagttact gataaatcat gagcaacagc tacagtcagt
    15481 gcgtcgtaag gaaccatatt caagataagg atgggctgag taaatccagc ttctctcaac
    15541 tcgactcctt catctaaatt tgaaacacaa aagcccgaag ctccacctgc aactgctgcc
    15601 tcagctgttt caatagctcc atgaccgtat ccgttcgctt ttactactgc aaacaattct
    15661 tttccttgcg gaagtcttgc aacttcattt gctacatttt cagttatagc ttttttatgt
    15721 atcactgctt tcgttgggcg gtgccaagcg acaaccatcg tttttccttc tttctagtct
    15781 tccaaaataa tttgtgcaaa agctgtttca tttgtatgag taatactgac ccatacattg
    15841 ccttcatgag gtgaacgcgt cacaacaggc tgaccatttt cattttttaa aatctcgaca
    15901 tcttgaaagg taacttttcc gatcccagtt ccccaagctt tagagaaagc ctctttgcaa
    15961 gcgtaacgcc cgcctaaaaa ttctacttgg cgatgaaaag gcaaggactg gaatagtttc
    16021 atttcatcag aggtcaagat tcgtgcaatg aattttggtt tttcttcgat cagccgagtg
    16081 atcctaggaa gttcgactgc atcgatccca attcctttta tcatatgctt ttctcttttc
    16141 aataaattta gaacactctc attctaccaa attataacca ttttgccaca aataagtcca
    16201 caaataacaa aaatgaaagt ttctcttaaa aaagagaaac tttcatttta tgtttaatcg
    16261 ttatttgaac ggattacaaa tccgcgtttt ttatcattgt gacgtttacc gccatctttt
    16321 tggctgttat tatttttgct ataaccgcct tttgatttgt ttccacgata attaccgccg
    16381 tcacgacgat tacggttgtt tccgccacca cgtttgccat ttttattgta tccttttttc
    16441 tgcattggca atgggcgttc tggtgtgatc ttcactggca ctgcatcagc tggatctttt
    16501 gctgtcgttt ttagcaaaag tgcaactaaa tcttgtgcag aatattcttc taataattta
    16561 tctgctgttt gcaggtattt atctagacca ttttctgcaa gttttgtttc gatttgttca
    16621 actgcagcac ctaattgacc tttgaatgct tctttttcgg ttggtggacg taaagtcgtc
    16681 atccgttttt tcgtcaagtt ttcaatcaca tgcaagtagt ccatttcatt tggtgtaacg
    16741 aaagtcacag acataccgcc ttttccggca cggcctgtac gtccgatacg gtgaacgtag
    16801 ctttctggat cttgagggat atcatagttg tacacatgag tgacacctga aatatctaat
    16861 ccacgtgcag caacgtctgt cgctacaagg atatctaaat gaccgctctt aaatgaacgc
    16921 aatacgctca ttcgtttttg ttgagacaaa tcgccatgga ttccttctgc acggtaaccg
    16981 cgtgcttcta atccgcgtgc caattcgtct acacggcgtt ttgtacgtcc gaagacgatt
    17041 gttaattcag gtgtttgaac atcaaacaag cgagtcatga tatcgaattt ttcgtattct
    17101 tttgcgcgga catagtattg atcgatcaag tcagctgtca tttctttcgc tttgatcttc
    17161 acatgatgtg gatttttcat gaatttaacg ccaatattct tgatagctgg cggcatcgtt
    17221 gctgagaaaa gtaatgtttg tctttgatca ggaacttgtg aaatgatttt ttcgatatct
    17281 tccaagaagc ccatattcaa catttcatct gcttcatcca aaactaatgt ttgaacggtt
    17341 ccaagtttca atgtgtggcg gttaatgtgg tcaagcatac gtcctggtgt acccacaacg
    17401 atatgtggac gatctttcaa gccacggatc tgacggccaa tatctgctcc gccgtaaacg
    17461 gcttgtacac gtactttttt gtcgcgccct aaacgatata attcttcttg tgtttggata
    17521 gctaattcac gtgttggtgc gataactaaa ccttgtaatt cgtgacgatc tggatcgatt
    17581 ttttctaaca ttggtaatcc aaatgcagct gttttccctg tacctgtctg tgcttgtcca
    17641 ataacgtctt ttccagctaa tgctagtgga atcgtttctg cttggatagg cgttgcttct
    17701 tcaaaaccag cgcgttcgac tgatttcaac aattctggtg ataattctag ttctttaaat
    17761 ttcaaatgaa tcctcctata tggttgttaa ctgaggatgt agcttttttg ctaccccgtc
    17821 gatttgttcg gtcaaagtgt attgtttctt tttgacagtg gccacgcacg tttttatcca
    17881 ttcttagccc ctgtggcacc accgaaaaat cactttgcga agtttaggca ttagaaaagc
    17941 caaacgggtc gcgttcagct ttatcattat tatgacatct ggcttcaaca agttgtttct
    18001 atggcaaaac cagtccaatt tctcttcatc tttcggcaat aggttattct aacatagttt
    18061 ttcgttttct gcaagtttac agatttttat ttcatttgct gaagttgttc taccacttca
    18121 aataagccca tgctgttgct gccttttagc ataatactat ctgttgcttc aagattttgt
    18181 ttgatagcat caatcaattt attcttttct ttttccaaat agaacacagg tagttggggg
    18241 tatttttggt tcaattcttc ttttagtgca tgcatttgtt ccccataaag gaaaatcatg
    18301 gcgaatttct caggatcgat atgttcactc atttgcgcat gcatatttaa agactctttc
    18361 cctaattcca gcatatctgc taacacagcg attctgcgtc cttttgttgg cagattttta
    18421 aaagtatcta ataccagtcc catggctgtt ggatttgcat tgtagacatc gctcaaaata
    18481 gctgcaccat ttcctgccgt tagccattcg gttctgtttt gagtgataga aacatgggcg
    18541 agcccttggc gtatctcagg tatggacagt ccaaagaagc gcccgatcgt atacgcaatc
    18601 aaagcattcg ttacattata acttccaggc agcgggatcg taaatgtttc tccttctact
    18661 acaaaatcgg tttgtgcttt tccttttgct gtcacttccg catgaacatc gccatttcca
    18721 ataccgaatg ttgtgactgt ttgtactaat gttgccgtta aaggtgtcag caacggttca
    18781 tctgcgggca caacgagtaa tccgtctgat acaagtccgt cagtgatttc cattttggct
    18841 ttagcgattc cttctcgcga cccaagattt tctatgtgtg cttcaccgat cattgtgatt
    18901 gctgcagctt ttggttgagc cataagtgaa agttccgtga tttcattggc gtgatccatg
    18961 cccatttcca aaacgatctt ttctgtatct tggggcatgt gcaaaatcgt gtaaggaaga
    19021 ccaatattat tgttgtaatt tccttgcgtc ttatatgttt tgtatttttc agacaagaca
    19081 gacgcggtta gatctttcgt ggtggtttta ccattgcttc ctgtaattgc aacgacttct
    19141 gcgcctactt tttccaagta ataggttgcc aattgctgca tggctttcaa aggatctgct
    19201 acaggaataa ctggaaaatt ttttggagct tgttcaacag gcaagctcca aaatgaagca
    19261 gatgctccgt ttgtgatcgc ttgctggata aattcatgtc catctcgcgt accagcaaga
    19321 ggaacgaata aacttccttc ggttatcttc cggctgtcaa attcgacatt ggtaatcttt
    19381 gtcagtgcag agcattcgct gcccacggct tgtgcaattt cttgtattgt tagattcatt
    19441 gagatctctc ctaaaaaagg ttgtgaaaaa agcgtttggc ctaaacggcg ggttcgcatg
    19501 actctcactt ccaagtaaat ttctctattc gtatttagaa gctagaatga acgcggttac
    19561 gcaatcactc cagcctcttc tttatttctc tttattcatt tttttcaaaa aaagattgac
    19621 gctgatggta tcgattcatt cctaactgga tcagttcttc aatcaaatca ccgtatttca
    19681 agcccatatt ttcccataag agtgggtaca tactgaactc cgtaaatcct ggcatagagt
    19741 ttaattcatt caggaataat tcatttttat ttgtcaaaaa gaaatcgcac cggctcaatc
    19801 cgcttccacc taacatcgtg taagctaact tcgcgtactc ttgcgctttt tgataaactt
    19861 cttctggcac ttcggctgga atctgcattt cgattttatt attgatatat tttgcttcat
    19921 aatcatagaa tgctacgtct tttacgactt caccaggcaa agtcgtccga acgtcttcat
    19981 ttcctaatac agcaacttcg atttcgcgcg cttcaattcc ttgttcaacg attgctcgag
    20041 aatcatactg ataggctgtt gctaaagcat tttgcagctc ttctcggttt tctgcttttg
    20101 taatgccgac actagaaccc atattcgccg gtttgacaaa catcggataa agcaaagaac
    20161 cttcacattg atcaaatact tttttaggat tttctttcca ttgattctta agtactggta
    20221 cataaggaac ttgcggcaca ccagcagctt gtaaaatata cttggtcatg attttatcca
    20281 tggcacatgc actggtcaat acgcctgcgc cgacataagg catattcaat gtctctaaga
    20341 agccttggat cgttccatct tccccgtttg gcccatgtaa aactggaaaa acgatggctc
    20401 cttcttcttt gatttcgccc ggattgatca cttttcctgt aaagccttcc tctgtctgtc
    20461 cacttgggtc ccatgaaaga tgcaagacat ctttgctggc aggtttttct gttagtaatg
    20521 gacctttgac ccattgtcct tcttttgtaa taaatacgag ttgaacttgg taataattat
    20581 aataaatggc atttaaaact gaaaatgcgg aaagaatgga cacttcatgc tctgcgctgc
    20641 gtccgccata tagtaaagta atcttcaaaa gattgtcctc ctgtattcta aatcgttcag
    20701 tgatttactc tcatatttta gcacaaaaca aaaataaacg aataacttat ttataaaaaa
    20761 acgagccagc ttctaaaaga acgagcgtca tttatttttt gtcagctaga ttatttgtcc
    20821 cgttttttat aaaaagttat gataaagaaa aggagggatg atgatggcgc aaacaaatcc
    20881 acgcagccgc ttggcagaaa tcattcgagt gttcatcaat tacaatgtag tgccaaactt
    20941 tgtacagcaa aaaaatcccg aacaggtaaa aaaagccttt gaagaactag gccccacctt
    21001 catcaagata ggacagatgc tttctgttcg agaagatttg ctttcttctg ccttcactca
    21061 aacattcaaa acattacaag atagtgtacc tagcgacaca ttttcaacgg tcaaaaagac
    21121 gatcgaaaca gaactttctc tttcattatc agatatattc gatgattttt caaaatcgcc
    21181 ttttgcctct gcttctatgg ggcaggctca tcgtgccaag ctgaagaacg gtgacgcggt
    21241 agtcgttaag atccaacacc ctaacatcgc cgaagagatc cgacttgatc ttcaactatt
    21301 tgaacgagcg atccctttga tcaaatacat tcctgaaact agcgtagttg atctaaaagg
    21361 ggtactccaa gaagtaaaac gttccttgat caatgaaatg gacttcttaa aagaaagtca
    21421 aaatggcgaa caattctatc aaaagaacaa tggctggaaa gagatccgca gccccaagat
    21481 ttatgacgct ttttgttcga aaaaagtgat cgtgatggaa gaaatgtctg gtaaaaactt
    21541 gaatcattta atgaacgccg aaaacaaaac tgaaactttt atcactggaa ttcaaaacaa
    21601 gcagctgaaa caagaagttg caaagctttt agttgagaac tttatgaaac aggtgtttga
    21661 tgatggtttt ttccatgctg atcctcatcc agggaatctg ctattccatg tactaacaaa
    21721 agaagaacag acacaagcta gccgaaaaac tgaaacagtc catgaaaaag agttcggttc
    21781 ctttgctttt cgagcctcca cttctgcaga agaccctgtt gcgccatata ccatcaacta
    21841 catcgatttt ggtatgatgg ggcatctttc tgcaggactt aggcaaaaac tcacacaagc
    21901 cgttttagcg ctgtatacga aagatgctta tcgaatcgaa aaagcggtcc ttcgactttg
    21961 tcagcaagaa ggctcgtttg atgaaagtcg gttccaccaa gaactgacaa gttttcttga
    22021 acagtattat gattctccta ttgatgaaat caacttgcaa gaagtattca cacatgtcgt
    22081 gacgatttgt catcaaaata atctgcagtt cgatcgtgat atcacgcttt tgctgaaagc
    22141 atttgggaca ttagaagggg tgatccgcgt cctcgatcct gaagtttccc tcatggaagt
    22201 cgcttcgcct tttgctcaac attattttct cactcatctg gatgtagaag atacattgaa
    22261 acaaagcgga ttagacttat tggaagggat gaaggctgcg cctaagatcc ctcaacagct
    22321 ccaccatcta ttagaaatgt ggacttcggg acaaggaaaa gtcaatttgg aattgaaaaa
    22381 gcaagacaaa ttattgagca ggatcgaaag tatgatcaat cggcttgttt tcggtatgat
    22441 tttagctgca ttgatcgtag ggtcctccct gcttgtccaa gcagcacctg tagaaaacgc
    22501 agaggtcgtt tccttattag ggatatttac gtatgctatt gccgcattcg tcattatttt
    22561 tttggcaatc gatgcattga tccaaatgta taagaagagg aaaaagtaga aaaaggttgt
    22621 gacagaaaga atcagcttca agaaataaga aggggtttta cataaattgt ttctcaaatt
    22681 tttgtgaaaa ttcggcttat ttttcgaaga ggctacttct gaaacaccga gaataaaaaa
    22741 tgtgaaaaag ctgttctgca cccagtaata agaacaatca aaaagggaac atggaacaca
    22801 tttatcctgt ttccctgttc cctttttgat gtattcgagc ataaataaaa taccttcgtt
    22861 acctactatc ttctgtactt ggtaaacctt agtcaattgc cttttttaac gcttgacgaa
    22921 aagacatatg atctttctcc gtaaagggtt ttggaccctt tgtccttatg ccagcttttc
    22981 ttaactttcc actatgataa cgttgttcta gaagcgtgcc gatattcgct tcgtcaaatt
    23041 cttttccaga gtgatggaac actcgcacac ccttcggcaa tacaagtgaa gctaaaccat
    23101 aatcttgcgt gatcaaaaag tcattcttct taaccatacc gacgatttta taatccgcac
    23161 tatcagctcc gcggtctacg tagacgattt ggacatgatt agcgtattct ttggtcgtat
    23221 aatggtccac actggtcacg ataaccacgt caagaccata ggattctcct aattttatga
    23281 catcttcttt tactggagaa ccatctccat caatgaatag cctcattctt tttcgccttc
    23341 ttccataaat gataaacagt tactaatccg ctcagtaaaa gaccaacatt gatccatttt
    23401 gccaagataa gcagttgtac actttctatc ggcactgatt catggttcag cgtgatcaat
    23461 aatagatgga ttggctctcc catttctttt gctaaaacaa acaaaagcgt catcaataaa
    23521 aactggtgga tcacactccc tttattttga gtagtatact tgacaacgat ccggcgatcc
    23581 attggaatag ctgtatcagt ttgataatat tccttattta gccagctgcc tgttactacg
    23641 tgccagaaac taagcagaaa gacacctatc gcaaaaccat ttggaatcaa gaggaccaat
    23701 aaagaagaac tcagtccaag caattgcata gccaatggag accatgttaa acgtttcaaa
    23761 atccatggtc cgactatttt tgctgcaatc aagcctgctg cataaggcaa atacataaaa
    23821 atcgaaagtt tttctaatcc gtacagtatg ccaacataaa aactgctaaa taaaaaaagg
    23881 aaattcccta gcattccatt tagaaaagta aacagattta gccagcttgg caacttccat
    23941 tccttcttct ggtgtcctaa aacaaacacg aacaagatga acagcagcaa gaaaccataa
    24001 atagcaagat caaaaagcct ttcatcgaat aacaatcggg catttctcaa aagaaacaat
    24061 aagccaaaga atatcaaaaa taaaacaagc tctcgcgtag ctaccagatt tcttttgatg
    24121 tctttgaaat ccagttcgta acgcggataa tgactaaccg tatggtaggc catgacgtaa
    24181 aaaagtgtat aaatagtaaa gcttgctgca atctgagtcg gtgcaggcaa ctcaatcgct
    24241 tgatacagga gaaatagcca gatagctgca aataagtact ttttcccatc catattgata
    24301 aaaccttgcg tcttttcgtg aaaattgacc gtggtattag caggtacaag ccatgctgca
    24361 ctcagcccta gcaaaacact tgaaaaataa aataaaggaa aataaaatac gcctaatatt
    24421 ccaagcaatg aaccagcacc accaatcagc agagcgatca tcagcaacgt gtaactatct
    24481 agaccaaatc gtagactgtt gactaaaaat agtccagtca tccgaaaggc ataaaacagc
    24541 gtaaatggca aaatcgtcag ccaattatgc gagtctgtta gtcccaaaaa taaaagataa
    24601 ggaataaaaa taaccgtgtt acttaagata aagggcgttg tttgtgtaaa attacgccca
    24661 aatcgtttga gtttttcgaa catgacaatg gctccttaaa cagtcttata actaatctgc
    24721 tcttcgattt tagcattaaa ggggaaataa accaatttta cagaatatat tcttgtaaaa
    24781 aaaaatacag aaagaagcat aagcttcttt ctgcattttt acggtacttg attactcaag
    24841 cagacaagcc cttctccaca aaagtcttgc ccgacacccc tgcatccggc aggtgataaa
    24901 gatagaaatc aattatcctg tgcctccaaa atcaattagg agctctgtaa accagagtcc
    24961 ttctcgaccc gtcgcataaa tttactttaa cacagttcct atgtttatgc gagagctttt
    25021 ttcattttat aatcgaccat ttgaaatcct tgaccgatat ctgaaataag ttcttctgta
    25081 atctcaaatc cttcatgctt ataaacctcg attgcttgat gattcccctg attcactcgc
    25141 aaaaagatct ctctttcctt tgtttgcgca gcaagttctt cataccagcg aaaaactgaa
    25201 gaagtcaatc cttgaccacg tactttattt agcaaatata atttacttaa ataaattttt
    25261 ccatttatct cttcataagc agtgtaaccg acagtctttt cttcgctttt taataaaaag
    25321 taggacacac cttctgtcag ttctttttga atctgttttt ttgactgata agttttcagc
    25381 atgtaatcca cttgtttttg accaatgatc ggcacaaaag cttccggcca tacttcttgt
    25441 atgactgcca tcagctcatc cagttcattt tctgttactt ttattttttc catacaccca
    25501 cgtccttttt tacattataa atgaccttgc gcttgatgga ataaaaagag catgatcatg
    25561 ctatacacac ccaccgacca tggtttcaag aaaatcacaa tctgcataaa ttccctaaaa
    25621 gataatttcg tcaaaccagc tactagacag atcaagtcgt ctggcgcaaa gggaagcagc
    25681 aaggtaacaa ctagtacttt tttaatatct ttcgtttttc ttgtcagcaa ttcatcaaat
    25741 ttctgatact tttttggcga taaaataagc tggacaaagg ctacgccata gtaacggaca
    25801 agcaaaaatc cgattgcttc cccaatcact aggccaatac aactatataa aagcccaaat
    25861 ccattgccaa acatcagcat gcccgctact gaggagatcc ctcccggcaa aataggaatg
    25921 atcacttgga tcacttgcaa cagaacaaat atcatcactg catacttgcc aaattgctgg
    25981 ataaacgctt gcaaagacgt gctcgatcga aaaatcccat gatgataagc ataaagaatc
    26041 aacacaaaga aaaaaaacag accaataatg ggcatgatct gaagacattt ttgtaaaact
    26101 gatccttttt tagacatcta tattccccac atcttttttc atttattaaa actgcctcct
    26161 t
//
LOCUS       DAZUJR010000036        25680 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.036, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000036 DAZUJR010000000
VERSION     DAZUJR010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25680
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.036"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            279..1127
                     /locus_tag="ACG804_001420"
     CDS             279..1127
                     /locus_tag="ACG804_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SWIM zinc finger family protein"
                     /protein_id="HFS4832359.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
     gene            complement(1298..1639)
                     /locus_tag="ACG804_001421"
     CDS             complement(1298..1639)
                     /locus_tag="ACG804_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HFS4832360.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SVEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAVEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            1725..2432
                     /locus_tag="ACG804_001422"
     CDS             1725..2432
                     /locus_tag="ACG804_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HFS4832361.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            2419..2742
                     /locus_tag="ACG804_001423"
     CDS             2419..2742
                     /locus_tag="ACG804_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HFS4832362.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(2831..3868)
                     /locus_tag="ACG804_001424"
     CDS             complement(2831..3868)
                     /locus_tag="ACG804_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HFS4832363.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(4315..5298)
                     /locus_tag="ACG804_001425"
     CDS             complement(4315..5298)
                     /locus_tag="ACG804_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase"
                     /protein_id="HFS4832364.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ"
     gene            complement(5714..6484)
                     /locus_tag="ACG804_001426"
     CDS             complement(5714..6484)
                     /locus_tag="ACG804_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4832365.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(6477..7412)
                     /locus_tag="ACG804_001427"
     CDS             complement(6477..7412)
                     /locus_tag="ACG804_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4832366.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(8006..9655)
                     /locus_tag="ACG804_001428"
     CDS             complement(8006..9655)
                     /locus_tag="ACG804_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HFS4832367.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLNYPKSIVEQAQKESLLFDEQRQWYPFD"
     gene            complement(9850..10746)
                     /locus_tag="ACG804_001429"
     CDS             complement(9850..10746)
                     /locus_tag="ACG804_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFS4832368.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWVDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDSFIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(10739..11419)
                     /locus_tag="ACG804_001430"
     CDS             complement(10739..11419)
                     /locus_tag="ACG804_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFS4832369.1"
                     /translation="MFLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(11420..12202)
                     /locus_tag="ACG804_001431"
     CDS             complement(11420..12202)
                     /locus_tag="ACG804_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFS4832370.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(12195..13112)
                     /locus_tag="ACG804_001432"
     CDS             complement(12195..13112)
                     /locus_tag="ACG804_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFS4832371.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(13115..13399)
                     /locus_tag="ACG804_001433"
     CDS             complement(13115..13399)
                     /locus_tag="ACG804_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832372.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWQTTQPRLRDSLIFLEIQLENLHFLYTFLAAFFIPVNYTSLINKKEG"
     gene            14187..17414
                     /gene="fss3"
                     /locus_tag="ACG804_001434"
     CDS             14187..17414
                     /gene="fss3"
                     /locus_tag="ACG804_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HFS4832373.1"
                     /translation="MYKKQKKKLCVLTILSLAVQSIVGAIAPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCVEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIADYQKKPSFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENTANIDYRVN
                     GNQLIISPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTVKIDVE
                     MEGSLKIKKVDKESGDIIPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTATIKAGETISVTSKNTREKGQIILDKTGIETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGHETQGKAEFKRAEYTL
                     FTVKDGKAVKWTENFKPELLKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDSEKNAVITRDVAAKEQVIRFGFDFFKFAGSTTGTAETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDYTKSDYIFTITEKGQKQPIKTVTVPYGNLTNENFSVSLNR
                     LMLYDLPEEEDSLTSLATWKEGDKELTTLDSTELVDKLSYNLHEIKEDWYIVAQAIDV
                     DATKAAQEKDKKAKPVAIAETTATLANKEKTGTWEILHKLTVEQVLDKTIVLFNYVYE
                     SKEAYEAGDEPVAKDASLNNQAQTVNCMVERHVSIQTKAHLEEGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALFPDGTSKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYDKDGNINGKHNEDLKEKSQTLTPKKVPTTPSTPEQSEMPTVP
                     SGSQESSPTVKAFPQTGEKTSNVLLFIGFSLIFATAGYYFWNRRN"
     gene            17526..17840
                     /locus_tag="ACG804_001435"
     CDS             17526..17840
                     /locus_tag="ACG804_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFS4832374.1"
                     /translation="MELKFVVPDMVETFGKLTYGGEGEVLSEGYGRNTTIVGRSYHLF
                     SNKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLIAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            17853..18227
                     /locus_tag="ACG804_001436"
     CDS             17853..18227
                     /locus_tag="ACG804_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFS4832375.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQLNQGKPTNQNEGKK"
     gene            18237..18581
                     /locus_tag="ACG804_001437"
     CDS             18237..18581
                     /locus_tag="ACG804_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HFS4832376.1"
                     /translation="MEINVEHILDCLDQFGKGELTEEQLTNALTYDEKMFLIMHQGLL
                     EVGNDAKEDFDVLDWLGEEESFFMVVEVNESLCRQAESVLEEIDVEMPDAIERFLKQL
                     VETKQLPVVVND"
     gene            18650..19666
                     /locus_tag="ACG804_001438"
     CDS             18650..19666
                     /locus_tag="ACG804_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HFS4832377.1"
                     /translation="MYKGHRIRAGDQHLIYHFVLGWLIFLFIGWMSVFYLQELRQFDI
                     SKVSFSTSEIGWSMKDVICLLGSLALSGSMMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQGEGFFKDLNSSWTKESISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LENKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIEEIVAENGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIQALLKSDAELFILDPKNADLADLGTIMPHVYSQK
                     EEISECVEDFYERMIARSRSMKEMPNYKTGENYAYLGLPPNFLIFDEYVAYMGANRFP
                     TSIE"
     gene            20260..22134
                     /gene="ltrA"
                     /locus_tag="ACG804_001439"
     CDS             20260..22134
                     /gene="ltrA"
                     /locus_tag="ACG804_001439"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFS4832378.1"
                     /translation="MNVETDEVQGSGKNVGKSVMEVPRLNTKIRYWEYYDLQETFDQL
                     FTQSRNGKKFYQLYELIISENNILLAYRTIKANKGSSTPGTDSFTIDNYKEMNQAEFI
                     HLILSHLENYKPKSIKRVMIPKPNGEKRPLGIPCMIDRMIQQMFKQILEPICEAKFYE
                     HSYGFRPLRSAKHALGRIMYLINISKMHYAVDIDIKGFFDNVNHRLLIKQLWNIGICD
                     KQVLAILSKSLKSPIQGEGIPSKGTIQGGIISPLLSNVVLNDLDHWVSKQWHTFETKY
                     PYTKGYNKFRALRDTNLKQGYIVRYADDFKIMTNDYPTALKWFHAVKLYLKDRLKLDI
                     SNEKSKIVNLRKCKSEFLGFAICVKQKGKKWVCNSRISNKKKDQIKEEIKQRIKDIQK
                     SPTAQNALLFNALVLGVHNYFRYATHINLDLNRMNYVLSFTTYNRLSNCSTRCYPNKA
                     SPTYKKFYSTTMKTYKVAGVYLYPLCDVSTKTIYGFNTEDTPFTPFGRQRLEHKSLQS
                     LVFQELRKLMESKIPNRTVEYLDSRISRYSMKSGKCEITKQFLPAKAVHCHHYLPKSL
                     GGDDKFDNLRIIHKDIHLLIHTTNKMIIDHYVHELKLVPEQIAKINLYRKMCNLQNIQ
                     "
     gene            22236..22616
                     /locus_tag="ACG804_001440"
                     /pseudo
     CDS             22236..22616
                     /locus_tag="ACG804_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            22661..23803
                     /gene="dcm"
                     /locus_tag="ACG804_001441"
     CDS             22661..23803
                     /gene="dcm"
                     /locus_tag="ACG804_001441"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HFS4832379.1"
                     /translation="MTFLDLFAGIGGFRLGMEQAGHQCIGFCEIDEFARRSYKAIHDT
                     RKEVEMHDITSVSDEFVRSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     ATLLQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQSRERI
                     FLIGHSRDACTEQVFPIIGSSSTSDQNIRNLVNINPSNRGMGGQVYGSDSVAPTLTGD
                     EGIKIALPVKDGISVAGMLSGNFEQGNRIYEVTGTAPTLSTKQGGTKIMIRKNETEYQ
                     EVKPGDSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKGVKAYDL"
     gene            23793..24082
                     /locus_tag="ACG804_001442"
                     /pseudo
     CDS             23793..24082
                     /locus_tag="ACG804_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            24338..25522
                     /gene="mobT"
                     /locus_tag="ACG804_001443"
     CDS             24338..25522
                     /gene="mobT"
                     /locus_tag="ACG804_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobT family relaxase"
                     /protein_id="HFS4832380.1"
                     /translation="MAQRNLDYRLLKERRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     IASTKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDVRKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYYAIQDLL
                     KGRSIESTTFSIINRYLRFADKVDGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     IV"
     gene            25519..25632
                     /locus_tag="ACG804_001444"
     CDS             25519..25632
                     /locus_tag="ACG804_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HFS4832381.1"
                     /translation="MKRGILMEIVKDMLLVLGGSMLGVTVMCLMNASAAAD"
BASE COUNT         8057 a         4994 c         5032 g         7597 t
ORIGIN      
        1 tctttgcgat acatcatacc tcttttatca attggaacaa ttatttattt ctaacaaaat
       61 cacttcattt ttgtcagata aataaaaaac aaaaaaagtt ccatctttaa aacacgctat
      121 tcttttactt tttctcacat tctctaagaa aagaaaagga gaatgaattt ttgacaattc
      181 gagcaaaagt gattatcaaa tatgtaaaat cagctacttt tttcttaaac gtttctttat
      241 actaaatata aataagtgtt tcatgaaagg agaactagat gaataattgg cttgagtatt
      301 ttcctgaaaa cgttttggaa cgcggttaca gctatcatct gcacggtttt gtccgtcatt
      361 tgaactatac aagcaagtac ttgtccgcaa cagtttctgg cacggaagat tataaggtag
      421 tgatcacttg ggatgaaaag accaacatga cttgtgattg tctatatgcc atagaaggaa
      481 aaaaatgcaa acacatggct gctgtcttat tcgcttacga agaacgtcca ataaaaaaat
      541 ccaactactc actttccgaa ctctcgtccc ttgtttcctc cgctagttcc tctcttgtac
      601 gggagctttt aacagagatt cttatagaac atccgcactt tatcgaacgc ttcaaagtta
      661 agatgccatt tcatgcaata aattattcag ataaattaac aactatcatc cataaatacg
      721 atcatattat caagaaaaac aaaaacagga aaacagcgaa gttcatcatg gagatgcgaa
      781 agttcatcca agaagcagtt gaatcgctta ttcagcaaaa tgcctatctt cccgcattcg
      841 aattgatcaa tgaagtgatt gctactctcg aaacattcta ttgggagcct gaggatgaac
      901 gaacccttct tctgatagag gactgttatt atttatggaa agaattatta gcagaagcac
      961 ctcatgcaga aaaaaggcaa atgttctctt ggttcgtctg ccaagtcgat catactgacg
     1021 cctcttattc aaaacgctac tctataaaaa tcctgaaaga agactttcgg gaaaaagaat
     1081 tttctaacca aaagaaaaaa atagataaaa aactaaagaa acggtaaaga aagacgattt
     1141 caatgaaaaa tagcaagtaa acgataacaa ccatcctaaa tccacaagaa atacagcaga
     1201 ccttgcttta aaaacacgaa tcatgcaaag gatgaagtaa agaagactta acgcgtaccc
     1261 aatattagtc atttgactat taggtacgcg ttttgtttta taagtcatga caaatttcct
     1321 tcgttgctgg atagattttc cggcattgtt gatagatttt atgatacttt tctacatttt
     1381 gtaagagagg ttccactgca tctgtatatt ggataaaatt ctgacaacaa ctttcaggtg
     1441 tgtcgaacca ccctaaccct agtgcagcaa tcattgttgc gcctaatgca ggtccttcct
     1501 ccacacttaa acaatagacc gttgcatcga aaatatcagc ttggatttgt agccatgcaa
     1561 gatttttcgc gcctcctccc accgaaacaa tacgtgtaaa tctgcgaccc gctagttctt
     1621 tacgtttcaa tcccaccatt gacaaatgct cattaaaaat ttagaatatt cacaagttta
     1681 acgacaatta tgaaaattta tgtcgtgcta aaggagtttt gttattggat gaaaagttag
     1741 atataaaaac tgcgatcaaa gacacgttac ctaccgtttt cggttatatc ggtattggac
     1801 ttgcatttgg tatcgttggg aaagctgccg gatttcatcc actagtcgtc acgttgatgt
     1861 ccctgctggt ctatgctggt tctgcccaat ttatcacagt cagcatgctt gctagtcaca
     1921 gcccattgct ttccatcgtt ttctcgacct ttctagtcaa ttcccgaatg attctgatga
     1981 gtatgacgat tgctccttat ttcaagaaaa atcggctgct tcaaaatctg ctgattggca
     2041 cattgctgac agatgaaagt ttcgcactgg gaatgaataa attgaactat actggacaaa
     2101 agttaaactt tcgttggatg aatacagcta attggatttc ttatttgacg tgggtgggtt
     2161 cttctcttgt tggcgcactt ttagggaatt ttattactga tccgaaaaag tttggtttgg
     2221 atttcgccat cgtcgctatg tttatcgggt tactttatct tcaagtcatt tctgatagaa
     2281 acacctctaa acgattacag ttgatcctga ttggtctcac tttgattctg gtatatgtcg
     2341 gactgatttt tatcccaagc aacttagtga ttgtagttgt aacactgatt gggtgcggat
     2401 tgggggtgtg gatcaaacat gccttctttt gagtttacat tgctgactat tttaggttgt
     2461 actttagcaa cttggctttc tagggtccta ccatttgtct tactgaaaaa attcgattta
     2521 ccgcaaccgt tgcttgagta tttaagtttt gtcccgatcg tcattatgtc tgctttatgg
     2581 ttcagcagtc tatttaccca aaatatcgga catctgccgc agatcaatct cgaaaatgct
     2641 ttggcttcag ttcctacact tttagctgct attctttcaa aaagcttatt ggtgatcgtc
     2701 ttggcaggaa ttctttccct ttcgttgatt cgcttattat aaataaaaaa acaagagctt
     2761 atggcaaatt actgtcatgc gctcttgttt ttatcaaagt caaataagaa aaaaatcggc
     2821 gtattcttgc ttatccgttg aacggaccac taacaacgac ttttcctaac atatgtcctg
     2881 tttctacgtc tttggttgct tgtttcaagt tcttcgcatt catcccatct gaatagacct
     2941 tgctcaatgt actgcggata atcccttcat ttgctaaagc agcaatgtgc gctaaagctt
     3001 ctccttgcgt ttcgatttca tagttatagt ctgttttagc gaacatatac tcccagtcga
     3061 agctgataga ttggtttttc caaacaccta tatctaacgg ctctttgatc cctacgatcg
     3121 ttcccacatg tccaaatggt cggacaaggt gcttgatttg atcaaagtag cgggtaatat
     3181 cgaataatac agcgacatac tctacttgat cgattcctaa ttcacgaaaa cttttactta
     3241 agtcgtgatg ataatcgatt ggatagtcta cacctgtttt tttcagccat tcaaaattct
     3301 tcggacttgc agtcgcgtag acttctaggc cagcccaatg cgctagttga ttcaaaatcg
     3361 aaccgacgcc cccggatccg ttgatcacta agattttttt cccgcgattg gcattttctt
     3421 ctggagttag accaaatttt tcaaataaca attcataagc ggtcaatgag gtcaacggca
     3481 aggctgcagc ttcttcatct gaaagatttt ttggtgcaag agcgacaata cgttcgtcaa
     3541 ctagttggta ttcttgattg cttcctgctc ttgttgttgt acctgcgtaa aaaacgcgat
     3601 cgccgacaga aaatttttgc acttcgtcac ctacagcaac aactttcccg actccatcaa
     3661 aacctaagat acgtaaagca tttcttatcc cgttatcttg gcgaagtttc gtatcgacag
     3721 gattaacaga tactgcgttg acttttacca gaagatcccg tgaactgggt acaggtatct
     3781 gttctttttc atcaataaag ctttttggat catcgatcgg caacccttca taaaaaccga
     3841 ctaccttcat taattccttt tctgacatac gaattcctcc ttagcttcat caagttggag
     3901 catccataca gtgttcattt caatatatat agtatgctat ttgttccacc ttttttattc
     3961 atcataatta ttctcttact taaagtaaac tatttgcact tttttggtta aaaaagaggt
     4021 tgcgacaaga cttttgtcac aacctcttat aaacggtgtt ctcctaccaa ctcttcggtc
     4081 acaagtcaaa atattcatca aacatgagaa gctgtttttt gaaattgctc cttgtgactc
     4141 agagttaaac ggcaggctca caacctctga tataaacggt gttcaatcaa ctgaccctcg
     4201 gtattagctc aaaaaacgac aaaatatgaa gagctatttt tgtttggctg ttcttattac
     4261 ttgatacagg acagcttttt cacgacctct aattcacggt gttcaagcaa gaaatcattg
     4321 ttcactgaaa agcgttggat gttctttttc aaaggtctct aagatctctc gtacttcatc
     4381 agtagatttc gtattcatca actgaactcg caagtcattt gctcctggaa atcctttgat
     4441 atagatttta aagaaacgat gtagtcctgt gatggaacgc gggatgattt ctgaataatg
     4501 atcttgcaga tctagttgca gacgaagtag tccgatcagt tctttttctg tatgttccct
     4561 cgggtctttt tcaaatgcat aaggattctt gaaaatccct cggccaatca tgatgccatc
     4621 aacgccatat ttctcggcca attcttctcc tgtctggcga tcggggatat ctccattgat
     4681 cgtgattagt gtttgtggag cgatttggtc acgtaaagca atgattttag gaatgacttc
     4741 ccaatgtgca tctactttac tcatctcttt acgcgtacgc aaatggacag aaagattggc
     4801 tatatcttga tgaagtaggt gactgatcca ttcttccatc tcagacattt ccgtatagcc
     4861 gatacgcgtc ttgacgctga caggcaaacc gccagcttta gctgcttcaa tcaattgtgc
     4921 cgctacttct ggacgaagga tcaagccact gccttttcca cgttctgcta cattagggac
     4981 tgggcagccc atgttgatat cgattccttg gaagcccatt tctgccatag caatgctcat
     5041 ttctctaaaa aattctggct tgtctcccca aatatgggca accatcggct gttcatcttc
     5101 tgtaaatgtt aatcttcctc gtacactgtc ttttccatct ggatgacaga aactgtctga
     5161 gtttgtaaac tcagtaaaga agacatccgg tgctgctgca tgctttacga catggcgaaa
     5221 tacaacatct gttacatctt ccattggtgc taaaacaaaa aaaggctttg gcagctcttt
     5281 ccaaaaatta gtagtcattt atttgttact ctccattcta tcaagcagtg aagtcgcaat
     5341 ctttctcaaa aacattgtca ttatactagg aaacaaaaaa agaagcaaag tgaacagctt
     5401 aaaagatgtt tctgattgag caaaaaaaag actgtgacaa aaatcttatc acagtccatt
     5461 ttccggaata aatggtgttc aaaagcttgc atctgcggta ataagtccaa ccaaacgaaa
     5521 aataggagga gctatttttg tttggctgtt cttattactt gatgcagaac agctttttca
     5581 caacctctcc actaaacggt gttcaatcag ctgaccctcg gtattcgctc aaaaaacaac
     5641 aaaatatgag gaactatttt cccgtttgtt tctctaatac tcaggtcaaa acgctgattt
     5701 cacaacctct tttctaactt ctcaatcctc ttcctttatt gatcaaatac caagtaacgg
     5761 cgtacaaaac aacgatgaat aacacaagta cgatcatcga tgttgctact ggcacatcga
     5821 tcgttccaag gaatccgtaa cggaaaccgg agatcatata aacgatcgga ttgacttttg
     5881 aaacagcttg ccaaaagggc ggtaacatag agatggcata gaaaacgcca cctagataag
     5941 ttaacggctg caagacaaat gtaggcacga tcgatacatc atcataagac tgagcaaaaa
     6001 tcccgttgag cagtcctgct aatgaaaaca agattgccgt catcaataat gtaatgatga
     6061 ccatgaacca tgaatacaca tgaagtggta caaagaacaa ggaaatgatc gttacgagag
     6121 agccgacgag aatactgcga cccacaccac caatcacaaa gccccaaata atcacatgcg
     6181 taggaacagg tgctaccaag atttcttcga tatttttctg aaatttttga gagaagaagg
     6241 acgaagaaac attggcatac gaactagtga tagcagacat cataatcaaa ccaggaacga
     6301 tgaattccat atatgaaaaa ccacccatgt caccgatccg cccaccgatc atttttccga
     6361 aaataacaaa atacaaggat gtcgtgatca ctggcggaac cagtgtttgg acccatatac
     6421 gcaaatagcg gttcgtttcc ttgatagcta aactttttaa tgcagtaaaa taaagattaa
     6481 acatttttct cctccgtatg attattttct tctgtgattt tcaagaacag ttcttctaaa
     6541 cgattcgact tattcctcat agaaagaact ttgattcctt gtcttgtaag ctgatcgaag
     6601 attccgttca ccccttgatt tcgttcaact tcgacagcga ttgtctgctc atcttcaaat
     6661 gtacaagcat atccttcaat cacaggtttg gtatcatatg gcgctaaatc aaagataaat
     6721 gtttcaaatt gcagttttga cagaagctct ttcatacttg tattctcgat cagttcaccc
     6781 gattggatga ttccgatgtt gcgacaaagc atttcagctt cttctagata atgcgtcgtc
     6841 aaaatgatcg ttgtaccatt ttcgttcaat tctcgtagaa actcccacat ctcgcgtctc
     6901 aactcgatgt caactcctgc tgttggttca tccaagatca gcaaacgtgg ttcatgcatc
     6961 aatgccctag caatcatcag tcttcgcttc attcccccgg aaagcatacg tgcacggaca
     7021 tttctctttt cccaaagatt ggactgcttc aaatattttt cgctgcgttt catcgcttct
     7081 ttgcgagaga caccgtagta gcctgcttga ttcacgacga tttgctggac cgtttcaaaa
     7141 gggttaaaat tgaactcttg tggaaccaat ccaatctgtt gctttgctcg aactagatcc
     7201 ttgtccagat cataaccgaa gacattcact tttccagatg ttttattgac taaagaagta
     7261 ataatcccga tcgttgtaga cttcccagct ccatttggcc ctaatagcgc atagaaatct
     7321 ccttctttca ccgaaagatc gattccccgc aatgcttcga ccccacttcc atagatcttt
     7381 ttcaaattat ttatttcaag cgcatttgcc atttatttcc tatctcctta tagacatgat
     7441 tcttaattgt atcatggaat acagcagatg aaaaaacaac ttggcttcca cacaaaaaca
     7501 cacctgctaa caaagaggag atgtgttttc tagttcatga tcatcttcga tagaataact
     7561 atctaaacaa ctctggaact tttaaaatca taaaagtacc gacagcaact actacgatga
     7621 catatagaag atccttataa ctgaggttct tgtctttttt attcatgtta agctttcctc
     7681 cgtcctttta tcgaaagctt ttttctttta ttttaaccga aataaataaa atggaaatag
     7741 ttattttcaa tttctgtttt cgctgtttgt tttacggaga actttgccat ggaacgtgcg
     7801 tctcgtcgct gatgctaagt tttttcgata aaagctgcta gaaggaagac agcgtggttt
     7861 attttgtatc gtcttttgct aaatcttcca agatcatctg gacagcagac tcgttcccat
     7921 tgaattctgc cacttttttg gcatcaatgt acttcttttg ataatcgtct ttttggaccc
     7981 acgcatcatg cttcgtttga taaagttaat caaacggata ccactgacgc tgttcatcga
     8041 acaacaaact ttctttttgg gcctgttcaa ctatggattt aggataattc aaaactttca
     8101 gcaaggcaat cgcatttcgg gtccttgaag gtccttcttt taatttgaaa tcaaaactga
     8161 ttccttttcc ttctgttact tgttcttcaa agtggacatt ctcacaataa ttctttaaaa
     8221 tctctgtcaa ttcgatatca tgtgtggcga caaatgctaa agatggatac tccgcaagcc
     8281 accgaacgac tgaagcggaa gaagcaatcc gttcgatcgt atttgttcct tttaaaatct
     8341 catctacgaa gcagtagcag cgttctttgg aagccacttg gtccagcaaa cgtttgatcg
     8401 atttgatttc tgaaacaaaa taactgtcgc cttcaaataa atcatcttcg attgccatgg
     8461 aagtcaacac atgtccaggt tgcagggtaa actgttctgc aatcgctgtt tggatcgtct
     8521 gtgctagaat acagctgatg gctatacttt tgacatacgt agattttcct gatgcattgg
     8581 aacccgtgac taatgtattc ttctgccagt tgactggatt aactaccgct tcttttaaca
     8641 atggatgata gatatctttc gctgtcacac cgccctcagt aaactctggt cggcaagtga
     8701 tcggcatata ggtgcgataa ttcaaaacgg ctgctgcaac ttccaattct cccagcaatt
     8761 cccacagctt gatggcttca gttgaatgct tttctaattt agtgagaacg aaatgatagg
     8821 agataaatgg cagcatgaac atgatgttga catattcaaa aatcaattct gcttcactcc
     8881 cgctcttcat tcgaaatgaa aaacctaatt tagggatgtc tcttaatggt ttagtttgct
     8941 gtttcagctc tttttgaagt ggtgtcgtca tttttgctaa ctgattggcg gctgaaatcg
     9001 ttgaaaccaa ataactcatg ctattcagct ctgtttctag tgtttgtttc ttcactagat
     9061 aatagaccgt attgaatact aagccaccga ttgctagata gattcctagt acttgcccta
     9121 aaagaagcaa acctacaccc accagcggaa gcaagccaag aaaaataaat aaacctacgc
     9181 gtccaatctt tttacttttt ccatccgcta gatattgttt tgcaaaatta tgatcttttt
     9241 ttcctaaacg agcgaattga tattggattc tttctctcag ttgaggattt tcctgataaa
     9301 aagcaattag tttttctaac tgataatctt ctccaaaatc aaagctacgt aaacgctgat
     9361 acaacgcttc tgaacctaca ctagaatagg tactgttgat cccttcaaat acttcgaaca
     9421 tatccaagtc ataccaagta agatcgtcga tttcactatc ccatgaacgg aattttttct
     9481 ccgtgagcca cgcatccttc aaactttctt ctttatcaaa tctcggttga taaggaattt
     9541 ttccccaatt actacgaact gtttccttta ctttcaaacg tgaaaaaatg tctaaaacaa
     9601 ctaataaaat aacaactgca ataataatta aaacgataaa ttctctttgg cccatatccc
     9661 tctccgttcc ttgatttgtt agttttagta tagcactgtt gcgctatttg aaaagggggt
     9721 acaaaaataa ctgtcttcgt tacctaattc gtatcaatca caccaaaata aaaacacctt
     9781 ccaaaaaaga agatgtcttt aaaacgagat acaatttttt gtcattcact tcaggtaaat
     9841 tagagccaat taaaccctcc gcaacttgac ggagatggag aagatgcccc cgtctaatct
     9901 agcggtcatc tctcctccca ttccttccac caattttttt gacaggtaaa gcccgattcc
     9961 gctagattcc gtatttgtgc ggctggtatt ttcggtataa aaacgctgga agactttttc
    10021 aacagaggtt tgcgctcctg gtttgatagg attggccact gttaatcgaa tgaatgaatc
    10081 ctcttttgaa aatgtcacct ttgcttgtcc atctgcataa cgcaataaat tctgtatgat
    10141 attttgcagc actcgcagca acatgagcgg atctgctaat acagttgtat ttatcgagtg
    10201 ttcagcgaac gctacctcga tatttttctc agaaaattgt tcataaaaag agaaaaatac
    10261 ttcttccacc tctttagaaa aagaaagcgt atggagatcc atttcttttt gcttcgtctc
    10321 tattcgagca agatcataaa actgatccgt catactgagt aatcttgcaa cagattgttt
    10381 gatgatcgtt aaatacttct cccgtttctc cgtatcctct acctgttcca gtaattgtac
    10441 ataaccgtta atagcagtca aaggagttct gagatcatga gaaaggccga cgatcgatag
    10501 tctgatgttt tcttccattt cttgaaatgc ttgtcctttt tgttcatttt catccaccca
    10561 tgtattcagt gcatctacta ggtccattag attcttttct cgaaattcga ctgaaagacg
    10621 accaccatat tcttgtcgtt cagaaagagt ggcgattttc ttagttaatc tcttgatttc
    10681 cctttgcagg aagaaaataa aacttcccat aaagataaca acgagaagca acagccactt
    10741 aatcaaatct aaaccccact ccccacaccg tatgaatata cacagcatgt gcctttgcta
    10801 gtttccctcg aagattggaa atatgcatat tcactgtttt ctcactatca aaatatggtt
    10861 cttgccaaac tgtttcataa agatttgctc gcgaaaatac ttttttcgga tgttctaaaa
    10921 aaagcttcag cagatcgaat tctcttcctg tcaaatggac agccacacca ttcacattta
    10981 catccctcga ctctttgtcc agtaagattt ccttgtaata gatgcgttgc gacagatctt
    11041 ttacttggac agaagtctga tgacgaagtt ggatgccgat tcgtaacaac agttcttcga
    11101 tatcaaatgg tttcgtcaca tagtcatccg ctcctgctgc caacaaggaa actttatctc
    11161 tttgatcgct ttttgctgaa agaacgatga tcggaacatt cgatgtctgt cggatttctg
    11221 ctaacaatgc ttcacctgaa agccctggaa gcatgagatc tagaaggatc aaatcgacag
    11281 gatatgtgct taacaataat tttccttccg tacctgaata agcatcaaga agtttgtatc
    11341 tctgttcaag aacctcctcc agtaaagaat gaacagcttc atcgtcttcg ataatcaaaa
    11401 tagtttccag caggaacacc tacttaatgt cagatttttg gaaaataaac attcctagag
    11461 ctgatgatac cacgattgtt actagactga ccagaatcat tttcggtgct tgcgaataag
    11521 ttgcttgttg cgcaaagtcc gtatacatga gccacgtttc cgtaaaccac tccgttagaa
    11581 attccaagcc tttgattttt gcgaaaacac cgggaacgaa ggccgttccc atgatataaa
    11641 gaaaagaaag aagcaaactg acactggtac ttctagtgat gaatgtcaaa gccactggaa
    11701 cagataatgt cgctaatatc agcagaagca atacaggaaa tacttttaga acataatttc
    11761 catagttttt gattccctca acttcaccaa atccgaaagc aagtgtgtaa gcaatcatgg
    11821 ctagccccgt aatcaaaacc acgccaagtg ttgtgatcaa aagcgtaacg agaagtttcg
    11881 acacataata agtcattcga ttccgtccta aagataacgt attgcgaatc gtaccgtttt
    11941 gaaattcttc cccaatataa aagcacgcaa atgctgcgaa agccagaaga atccatgcag
    12001 ccattttttc caccattaaa atccctgttg caccgttgat gactgtatcc gttgcttggt
    12061 ttaattcatt gccgtatttt gtatgcatat accattcgtt ccaagaataa aaaagcggaa
    12121 gtacgaccat cagtcctagt gagacccaca ttttacggct cttccatact tttatttttt
    12181 cagcagttaa tagattaaac atgtggattg cctccagtta attgtaagaa ataatcttcc
    12241 agtttttgcc caactaggtg gataccatcc acaggaactt ttgcctctac caatgcttga
    12301 ttgatggctg ctacttggtc aattccttca aaaagctgga taacacggct agattggaca
    12361 aaataatccc tataaccaag agagtcgaga accgttactg cttgttccgt cgccgaagtg
    12421 tcaattttta taaattgacg agattcttgt gccaattctt ctttcgataa ttctttgatc
    12481 aagtgtcctt catgcaaaat accgtagtga gtggcgatct gtgacaattc atctagcaag
    12541 tggctagaaa gcaagacggt gatgccccgt tcttttacca aacgttggat gatttctcgc
    12601 atttctgcca tccctgctgg atccatccca ttcgtcggtt catccaaaat caaaaattct
    12661 ggattcgtga tcagtgcatt tgcaatagct aaacgctggc gcatacctaa agagaaattc
    12721 tttgctttct ttttccctgt attttccaat cgcatcattt tcagcaggtc ttcgatttct
    12781 ctatccgaca caccgccgtt cgctgcttgg atacgtaggt tatctcttgc agttaattct
    12841 ggataaagag caggggtttc aatcgattga cccatacgtc gtcttgctgc ctgcaaatcc
    12901 gtcgttccaa ataattcgat cgaaccttca tcaatcgaga tcaaacccat aatagttctc
    12961 ataaaggtag acttacccgc tccattctcc ccaatcaaac catagatcat tccacgtttg
    13021 atttcgatcg atactttatc taatgctttg gcagcaccgt attttttggt tataccagtt
    13081 gctttcaaga ccgtttcatt tccaaaatcc atacttatcc ttctttctta ttgataagtg
    13141 aagtatagtt gacgggtata aagaaagcag ccagaaatgt ataaagaaag tgtaaatttt
    13201 ccaattgaat ttcaagaaaa atcagactgt ctcgcagacg tggttgagtt gtctgccaat
    13261 caaagagcgc accaaacagt gctaatccaa gtggactggc caccatggta atcgttgtta
    13321 tcgttgacat cagacgtcct tgtatatgcg ttggaacttc tcgctgaagc cagaccatat
    13381 aaaaagcaaa agaaaacatt aatccttaaa aacggactta tgaaaaataa tacatgccgt
    13441 ttgggattta caattagcta ccaaataaga ggttatgaca aaagactttt cacaatccct
    13501 tcttccgaat aaacggtgtt ctcctgccaa ctcctcggtc acaagtcaca atatttatca
    13561 aacatgagaa gcaatttttg taaattcctt cttatttctt gaagctgacc acttctgtca
    13621 caacctcaga agcggataaa taatattgtt tgatgatact ttatcttttt cccgtttgtt
    13681 tatagatcga atgatattat agaccaagaa tcctacctat taacatagct aaaaacacaa
    13741 aaaaggcact ttccaaattg tggaaagtgc cagaaaagtt aggattaagg taactgcgct
    13801 cagcattgct tcgcccagta cgattctcgt aactcgtgaa ctcgaacgat aatcgcaatt
    13861 aacgttttga gaactgtgaa gctttacggg ctttcttaag acctggtttt ttcttcgtat
    13921 cattgaataa gtttgaaaag ccttgattta taaaggtttt tccgtaaata tattttgtta
    13981 tatttgatta aatttgaaat gtttgtgttc taaaatgtgt tctaatttaa aggcagtata
    14041 tttcgtattt tatattaaat ttttaggctc attcattctc aaatccattc tatttagtca
    14101 ataaatattt taaaaagact ttataaacaa agatgttcaa gcgagcatct tatttttttg
    14161 tgcctaattt gaaaggagaa catttcatgt ataaaaaaca aaaaaagaaa ttatgtgtat
    14221 taactatttt gagtttggct gttcaatcaa ttgtaggagc aattgctcct acgattgctt
    14281 ttgctgatga aattacccat ccacaaacgg taaccgtaga actagattta gcacatcaat
    14341 atgctgttga aggaactttt agtgatggtc gtccaatgtc agaagtcact gttccgcatt
    14401 atgcagttta caatggtgtg aagcaagata ttttctgtgt tgaaccagga gtcccgattt
    14461 acaatgagtt cactcctgga tatgagaaga acccgttacc agatatgtcc gataaagcca
    14521 aattagtttc cgttttatgg aaaaaagtag gtacagatgc agatactcat attgtggcac
    14581 agaagatgat ctggcaagaa gttaatgggt atacccttca ctcaataaaa cgatcagatg
    14641 gtagtgccgt aaatatcgca gccattgagg caaaaatcaa tcaagccatt gccgattatc
    14701 agaagaaacc aagcttccat aatagtacgg ctaaaacagt attagggcaa tcgactactg
    14761 tgacggatac gaataatctg aatttgtcag agttcgatga ggttgtggaa aataccgcaa
    14821 acattgatta tcgtgtgaat ggcaatcagt tgataatcag cccaaatgcc aattcaaaag
    14881 aaagtggtgt gttgacgctt aagaaatctg ctggtaccgg aacacctgtc gcctataaaa
    14941 aggctggcca acagacttta atggccgggg cgatcgataa gccgaacact tatacggtca
    15001 aaattgatgt ggaaatggag ggttctttga agattaaaaa agttgataaa gaatcgggtg
    15061 atattatacc aggaacggtt ttccatttag actttggaaa aactttaccc gcaaaagacg
    15121 tgaccaccga taaagaaggc attgcgacct tagatgagat tcctcatggt acaaaggtaa
    15181 ccattactga aaaatcggtg ccggcgcctt atacgattga taccacaccc atgactgcca
    15241 caattaaagc aggtgaaacc atttcagtga cttcaaaaaa tacgcgagaa aaaggtcaaa
    15301 ttattctgga taaaaccgga attgaaacag ggagtgatct ttggaacgat aattactctt
    15361 tagcgggcaa tacgtttgcc attcgcaagg atagcccaac tggtgaaatc gtccaagaaa
    15421 tgaccacgga tgaaaaaggt catgcagaaa caccaaaaga gattgccaat gcgttggaat
    15481 tgggaaccta ctatgtgact gaaaccaagg ctagtcatgg ctttgtgaat actttcaaac
    15541 cagtaaaagt cgaattgaat tatgtcaatc aaacagtggc tcttgttacc agtaacgtaa
    15601 aagggcaaaa ccaagaaatt actggtgaaa ccactttgac aaaagaagac aaagataccg
    15661 gtcatgaaac tcaagggaaa gctgagttta aaagagctga atacaccttg tttactgtta
    15721 aggatggaaa agcggtcaaa tggaccgaga actttaaacc agaattgttg aagggaacga
    15781 aagcttctga tgaaaccgta actttgactt tagatgaaaa gaatcaagtt gccgttaaac
    15841 acttagcgat taatgagtat tactggcaag aaaccaaagc gcctgaagga tataccttgg
    15901 atgaaacaaa gtatcctgta tccatcaaaa aggtggatga tagcgaaaaa aatgctgtga
    15961 ttactcgaga tgttgcggca aaagaacaag tgattcgctt tggctttgat ttctttaaat
    16021 ttgctggatc aactactggc actgccgaaa ctggcttcaa tgatctaacc tttaaagtgt
    16081 cgccattgga aggaaccaat gaaatcaccg gtgccgaaga tgaagcgacc acagcttata
    16141 acgagcaatt agggtttgat ggttatggca agtttgaaaa tcttccttat ggggattatt
    16201 tacttgaaga agtagaagcc ccagaaggtt ttcaaaagat tacgccatta gaaatccgtt
    16261 ctacttttaa agaaaataaa gaggattata ccaagagtga ttatatcttt actattaccg
    16321 aaaaagggca aaagcaaccg attaaaacgg taacggtccc ttatgggaat ctaaccaatg
    16381 agaatttctc agtcagtttg aaccgtttga tgctttatga tttgcctgag gaagaagata
    16441 gcttaacttc tcttgcgact tggaaagaag gagataaaga attgactact cttgattcta
    16501 ccgagctagt cgataaattg agctataatc tacatgaaat caaagaagac tggtatatcg
    16561 tagctcaagc catcgatgta gatgctacaa aagctgccca agaaaaagat aaaaaagcca
    16621 aaccggtggc gattgcggaa acaaccgcaa ctttagcgaa taaagagaaa acaggaactt
    16681 gggagattct gcataaatta actgtcgaac aagttttaga caagaccatt gtcttattca
    16741 actatgtgta tgaaagcaaa gaagcctatg aagctggtga tgagccggta gcgaaggatg
    16801 ctagcttgaa caatcaagcg caaactgtta attgtatggt ggaacgtcat gtttccatcc
    16861 aaaccaaagc gcacttagaa gaaggttctc agacctttac tcatggtgac gtggtagata
    16921 tgtttgatga tgtatccatt acccatgatg tactagatgg ctcaaaagaa gcttttgaaa
    16981 caattctgta cgctttattt ccagatggta caagtaaaga aatttggaaa tctggcaaga
    17041 ttgattacga agtgaatgac aaagaattta ccaaaaccgt acttgcggaa aaagtggata
    17101 caagtaaata tccagaaggt acaagtttta ccttcaaaga aattaactat gacaaagatg
    17161 ggaatatcaa tggaaaacac aatgaagatt tgaaagaaaa atctcaaact ttaacgccca
    17221 aaaaagttcc gacaacacca agtacaccag aacaatctga aatgccaact gttccaagtg
    17281 gctctcaaga atctagtcct acagtgaagg cattccctca aaccggggag aaaacttcca
    17341 atgtgctact gttcattggc tttagcttga tctttgcgac ggctggctat tatttttgga
    17401 atcgtcggaa ctaaggtgat aagatgaaac atgtaaatag tagaaaacaa tacgcgcgac
    17461 cgcctcctaa aaaagtggtc gcgctatttt tgtattcaaa actaacaatg aaaagaggaa
    17521 aaaatatgga attgaaattt gttgtaccag atatggtcga gacgttcgga aaactaacat
    17581 acggtggtga aggtgaagtt ctatcggaag ggtatggtcg aaatactaca attgttggtc
    17641 gaagttacca tctgttttca aataaacaac gggccgatga tattgaagtg gtggtagctg
    17701 cggaagccgg cgaaaaggat tttgaccaag atcaaccact aaaagctgta aatccccact
    17761 taattgccaa aggctatgaa attgagaatc gtgggtttac cgattacgtg ttgtatgttg
    17821 atgatttagt gaaagcatag gaggaaaaga agatgagatt aacagaaggt attgtcgtag
    17881 attcaggatt aacctttggc aagttgcgtt tttccgcatt acgtcgagaa gtacgcaagc
    17941 aaaatgagga cggaacggtt agtaacgagg taaaagaacg gacctataat ttgaaatcct
    18001 ccgcgcaagg tcgaatgatc caagtcagta ttccagcaaa tgtaccctta cgcgagtttg
    18061 cttatgatgc agaggtagag ctggtcaatc caatcgtgga tacggtcgcc aattatgttt
    18121 ttcgggaagg aaccaccgtt aattggttta tcaaggcaga tgatttagtc ttgaaacgac
    18181 aactgaatca aggaaaacct acgaaccaaa atgaaggaaa gaaataggtg aagaatatgg
    18241 aaattaatgt tgaacatatt ttagattgtc tcgatcaatt tggcaaaggt gagctaacgg
    18301 aggaacaact cactaacgca ttaacctatg atgaaaaaat gtttctgatt atgcatcaag
    18361 ggttactgga agtaggtaac gatgccaaag aagactttga tgtactggat tggttagggg
    18421 aagaagagtc tttctttatg gttgtcgagg taaatgaaag tttatgtcgg caggcagaat
    18481 ctgttttgga agaaatcgat gtggagatgc cggatgccat cgaaagattt ttaaaacaat
    18541 tagtggaaac gaaacaactt cccgtagtag taaatgacta gcataacttt ttgaaattgc
    18601 ccaatgaaat cctattgggc tttttcgact ggaggtggaa accatcaaaa tgtacaaagg
    18661 acatcgcata cgcgcaggag atcaacactt gatttatcac tttgttcttg gctggctaat
    18721 ctttttgttc attggttgga tgagcgtctt ttatttacaa gaacttagac aatttgatat
    18781 ttctaaggta tcattttcca ctagtgaaat tggctggtct atgaaggatg taatctgctt
    18841 gctaggaagt ctcgctcttt caggaagcat gatgttactt tatatacact tttttcagga
    18901 tcattggcga agtctttggc atcgacaaaa gttagctcgg atgattctag aaaaccattg
    18961 gtatgaagta aagcagactc aaggtgaagg ttttttcaaa gatttgaata gtagttggac
    19021 caaagagagt atcagttact tccccaaaat ttattatcga atgaaagatg gcttactttc
    19081 tattcgcgtt caaatttcac tgggaaaata tcaggatcag ctattgaagt tggaaaataa
    19141 gttagaaagc ggactgtatt gtgagttagt agaaaaagaa ctcaaagact cctatgtgga
    19201 atacaccttg ttatacgata tgattgccaa tcgaattggg atagaagaaa tagtggcaga
    19261 aaatggggcg ttgcgattga tgaaaaatca agtatgggcg tatgattcct tgccgcatat
    19321 gttaattgct ggcggcacag gtggtgggaa gacctatttc ttactcacca ttattcaagc
    19381 actattgaag tcagatgcag aattgtttat cctcgatccc aaaaatgcgg acctcgccga
    19441 tttaggtacg ataatgcctc acgtatactc ccaaaaagaa gaaatttctg aatgtgtgga
    19501 agatttttac gaacgcatga tagctcgtag taggtcaatg aaagaaatgc ccaactacaa
    19561 aacaggagag aattatgcgt atctcggact tccgcccaac tttttaatct ttgatgaata
    19621 cgtggcttat atgggtgcga atcgttttcc tacaagcatc gaatagatgt gaaatggaag
    19681 cctattgaga ttatcaatag tgacaactaa tgttttgaga gatggaatga aagccttcaa
    19741 gttgagctga aacatccccg ctaatactcc tacatgctct aatcaatgaa gtagattggt
    19801 tttggtatga agctaggtga agtcgtctga aatctgccta agtgcttgag cataaggctg
    19861 actatagggc gggcggctga aaaagataac tatggtaaga atgtctgaaa atgactgacg
    19921 aatctgcgaa tgtacgggtc taaaaggctg atcttattga aagataggaa catacggacg
    19981 tatggtgaga taccgacaag taaggttcca tgatatgaaa atcgggatag ctaacgaaga
    20041 agctataatt tcacaggctc atagtagata cctaaggtta tacatgatag ctaaaaacat
    20101 tggaacgatg taagcagaaa actatcaatt aaatgactac ttctagatag gtgcatataa
    20161 gtaataacga aattgctttg tttctgtgaa agtaagggca cagtaccgat gaagcgtcta
    20221 acaaatgtgg agggatagcc ctaagtctat ttaataacaa tgaatgttga aacagatgaa
    20281 gttcaaggat ctggtaagaa cgtgggaaaa tccgttatgg aggtgccacg cttgaacaca
    20341 aaaatacgtt actgggaata ttatgatcta caagaaacat tcgatcagct atttactcaa
    20401 agtagaaacg ggaaaaagtt ttatcaatta tatgagttaa tcatttctga aaataatatt
    20461 cttttagcat accgtactat caaggcaaac aaggggtctt cgacaccagg aacggattcc
    20521 ttcacaattg ataactataa ggaaatgaac caagcagagt ttatccatct tattctcagt
    20581 catttagaaa attacaaacc aaaatccata aagcgagtaa tgatacctaa acccaatggt
    20641 gagaaacgcc cattaggaat tccatgcatg attgatcgaa tgatccaaca gatgttcaag
    20701 cagatactgg agccaatatg tgaagctaag ttttatgaac atagctacgg tttcagacca
    20761 ttgagaagtg caaagcatgc tctaggtcgc attatgtatc tcataaacat cagtaaaatg
    20821 cactatgcag tagacattga tatcaaaggt ttctttgata atgtaaacca ccgtttactg
    20881 ataaaacaat tatggaatat aggaatttgt gacaaacaag tcttagctat tctttcaaaa
    20941 tctctgaaat cacccattca aggagaaggt atcccgagca aaggaacgat ccaaggaggt
    21001 atcatttctc cactattatc taatgttgtt ctaaacgact tagaccattg ggtctcaaag
    21061 cagtggcata cctttgaaac aaagtatccc tatactaaag gttacaataa atttcgtgct
    21121 ctaagagata caaatctaaa gcaaggctat attgtcaggt acgcagatga ctttaaaatc
    21181 atgactaatg attatccgac agcattaaaa tggttccacg ctgtcaagct ttacctaaaa
    21241 gacagactta aattagatat ttccaatgag aagtctaaaa tcgtcaattt gcgtaaatgt
    21301 aagtcggaat ttttaggatt cgctatttgc gtgaaacaaa aagggaaaaa atgggtttgt
    21361 aattcacgta tttctaacaa aaaaaaggat cagattaaag aagagattaa acaaagaatc
    21421 aaagatattc aaaagagtcc tacagcacaa aatgctctcc tgtttaatgc tctcgtgctc
    21481 ggtgttcata attatttcag gtatgccact catattaatt tagatttgaa taggatgaac
    21541 tacgttcttt cattcactac ttacaaccga ttatcaaatt gtagtacaag atgttacccc
    21601 aacaaagctt ccccaactta caaaaagttt tactcaacaa cgatgaaaac gtataaagta
    21661 gctggagtct atttgtaccc tctttgcgac gtatctacaa aaacaattta cggatttaat
    21721 acggaggata caccgtttac tccgtttggt cgtcaaagat tggagcacaa aagcctacag
    21781 tctcttgtgt tccaagaatt aagaaaattg atggaatcga aaataccgaa tagaacggtt
    21841 gagtatttag atagtagaat atctcgttac tcaatgaaat caggcaagtg tgagattaca
    21901 aaacaatttt tgccagcaaa agccgttcac tgtcatcact atttgccaaa aagtcttggt
    21961 ggagacgaca aattcgataa cttgagaatt attcataagg atatccatct tctgatccat
    22021 acaacaaata aaatgataat cgatcactac gtgcatgaac tgaaactggt gccagagcaa
    22081 atagcaaaaa tcaaccttta tcgaaagatg tgtaatctgc aaaacattca atagaaaata
    22141 aatagatgga acgccgtatg aggtgaaagt ctcacgtacg gtgtggagcg ggggaaaaga
    22201 tggagattat atcaaattct tacctatcgc tatagatgtt aacgacaaaa gaaagtgcgg
    22261 tgattttgaa taagcttaaa caaatcgtga tgttaggccg tcaatctggt ttctttctga
    22321 ttctagcttg tcaaaggccg gatgcgaaat atctaggaga tgggattcgc gatcagttta
    22381 acttccgtgt ggctttgggt cgtatgagtg agcttgggta ttccatgatg tttggagaag
    22441 tcgataaaaa tttttttatg aaacgcatca aaggacgagg ttatgtagat acagggggca
    22501 gtgtgattag tgagttttat acgccacttg taccaaaagg gtatgatttc ttaagggaaa
    22561 ttagcaacat tgttggatta accgttcata cggaaagaga aaataatagt gtgtagccta
    22621 ggaatatcaa taatcctggg cttttttatt gaggtgattt atgacatttt tagatttatt
    22681 cgccgggatt ggtggctttc gcttaggtat ggaacaagcc ggtcaccagt gtatcggttt
    22741 ttgtgaaatt gatgaatttg ctcggaggag ttataaagca atccatgata caaggaagga
    22801 ggtggaaatg catgacatca caagtgtatc agacgaattt gttcgatccc tcggaccagt
    22861 ggacatcctt tgcggcggct ttccgtgcca agctttttca attgcgggaa agcggcaagg
    22921 attttccgat actcgaggta ctttattctt tgaaatcgct cggttcgcca ctcttctcca
    22981 acctaagttt ctattccttg agaacgtccg gggattgctc aatcacgaag gaggggctac
    23041 gttcgagacg atcctccgaa cgttggatgg attggggtat gatgtggaat ggcaagtgct
    23101 taactcaaag gcctacgttc cccaaagccg tgagcggatc ttccttatcg gacattctcg
    23161 agatgcatgt accgaacaag tatttcctat cattggatcg tcttcaacat ctgatcaaaa
    23221 catcagaaac ttggtaaata tcaatccttc caatcgagga atgggtggcc aagtctatgg
    23281 ttcagatagc gtagcaccaa ccttgaccgg tgatgaagga attaaaattg ccttaccggt
    23341 aaaggatggg atttctgtag cgggtatgtt gtcgggaaat tttgaacaag gcaataggat
    23401 ttatgaggta accggaacag cccccacttt gtcaacgaaa caagggggaa cgaagattat
    23461 gattcggaaa aatgaaacag aatatcaaga ggtgaagcca ggggacagtg tgaacctggc
    23521 ttttcctaat tccacaagtc gccgaggtcg tctgggaaaa caaagtgtgc ataccttact
    23581 aacaggagac caacaagcgg tagtcacgga tcagtaccag attcgaaagt taacacctag
    23641 ggagtgctgg cggcttcagg gctttccaga ttgggctttt gatcgagctt ctcaagtcaa
    23701 ttcagatagt cagttgtata aacaggccgg aaactcagta acagttccgg tcatttttga
    23761 tattgctaga agattaaagg gggtaaaagc atatgattta tgacgagttg attggagaaa
    23821 tctactggat gattggcaag attcaggcag atccgaaatt ggaagaagaa ctgtaccggc
    23881 tcaattttga tattcgcaaa aacggggtga aagtccaggt gattcgtatg tagtggatga
    23941 ggaaacggat gctcgaatgg agctcaatca agtcatcggt gaattggaac gaattgcgga
    24001 ccttgccaaa gaacctgata tccgccaata cttgtttgag ataaaagcag agttggaaat
    24061 tgagggtatc accgcggagt aatagggaaa taacccactg ataggcactg accgcggggg
    24121 atttgcgaag cagaaatcct ccgtggtgct gtgcctgttc atggacggcg gcagccggcc
    24181 atgatgtctc accccccgta tctaacaggg gggtacaaaa acacaaaaaa caagcaagta
    24241 accataaaaa atgcttgttg tatcaaggat attaagtaat ttgtataggt gttaactcat
    24301 ttggaaaagt taacaccttg aatttggagg tgaaaacttg gcgcaacgaa atttagatta
    24361 tcggttatta aaagaacgac gcaacgaata tggcgtttca caaaataaat tagctactgc
    24421 ttgcggactt agccgcccat acctaaatca gatagaaaac ggtggcgtaa tcgcctctac
    24481 aaagaccatg agaaaaattt ttgatcaact ggaaagtttc aatcccgatt tacctttaac
    24541 gttactattt gactatgtaa ggattcgctt tcccacaacg gatgtgcgga aaattattca
    24601 agaaattctc catttgaaat tcgagtatat gcttcatgaa gattacgcct tttactccta
    24661 tcaagaacaa tatgtcatgg gcgatattgt agtgatgtta tctcatgaag aagataaagg
    24721 tgtccttttg gaattaaaag gtcgtggttg ccggcagttt gaaacttttt tactcgccca
    24781 aaagcgtagc tggtacgact tttttgaaga ttgtctaaaa gccggtggcg tgatgaaacg
    24841 cttggattta gcaatcaatg atcgagtggg gctactggat attcctgatt taacgaaaaa
    24901 atgtcagaag gaagaatgta tctccttgtt tcgtaccttc aaaagttacc gttccgggga
    24961 actgttgaaa gctgatgaaa aggatggtat gggcaatacc ttatatattg gcagcctcaa
    25021 aagcgaggtt tatttttgtt tgtacgaaaa agattatgaa caatatatca agttagggat
    25081 tccattggac cagaccgaaa cgaaaaatcg ttttgagatt cggttgaaaa atgaccgtgc
    25141 ttattatgcg attcaagatt tgttaaaagg tcgtagcatt gaaagtacca cgttttccat
    25201 tatcaatcgg tatttgcgat ttgcggataa agtagatgga aaacggcgaa ccaattggcc
    25261 cttgaatgaa caatggggtc gttttattgg acggaatcgg aaagagattc aattaacttc
    25321 tgaaccgaaa ccgtatacca ttgaacgaac attaaattgg ctaggtagac aagtcgcccc
    25381 tacgtggaaa atggctaagg agttggatcg attgaatcaa acaacgtata tccaggatat
    25441 ggtacagaat gcgcgactct cggaccggca taaaaagatt ttggagcaac aaagtatggc
    25501 aatcgaaaac ttgattgtat gaaaagagga attttgatgg aaattgtaaa agatatgtta
    25561 ttggtacttg gtggcagtat gcttggtgtt accgtgatgt gcttgatgaa tgcaagtgca
    25621 gcagcggatt gagcaatgga aaagaaagga aagtgacaaa atgaatttcg gacaaaattt
//
LOCUS       DAZUJR010000037        25509 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.037, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000037 DAZUJR010000000
VERSION     DAZUJR010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25509
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.037"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..376
                     /locus_tag="ACG804_001445"
     CDS             <1..376
                     /locus_tag="ACG804_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFS4832382.1"
                     /translation="ITRHVWGDLMDEVEHLRLTDLNKSIYKKRKQTIERIFADAKEKH
                     GMRWTKYRGLEKVATHTMLVFAAMNLKKLATWLWKGKEPLFFCSKIRNEVDKKLFQAR
                     VTSLEQLLSTVWLSVRTAFFVG"
     gene            859..1002
                     /locus_tag="ACG804_001446"
     CDS             859..1002
                     /locus_tag="ACG804_001446"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HFS4832383.1"
                     /translation="MITAHSGSDNTEENSWAFLRFCLDRQLCFEVDVRQQTDGTLILA
                     HDR"
     gene            1048..1581
                     /locus_tag="ACG804_001447"
     CDS             1048..1581
                     /locus_tag="ACG804_001447"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832384.1"
                     /translation="MANEKATMTINCDLKEEGLEMAVFSLAQTYQIWPQIVLSGYVQL
                     SWAAIWGKHIFYNIENQFEGKKLGDITEADLIDTLQKLAYQSVQIVNIHEGWLTKLAR
                     EVGQQLGLTFSVWTVNELETIEYLARCGVYNITSRCAWAYLWKKGAQNKLFYNQNRGV
                     KRFGDGIHDHMGALFLA"
     gene            1725..3014
                     /locus_tag="ACG804_001448"
     CDS             1725..3014
                     /locus_tag="ACG804_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFS4832385.1"
                     /translation="MLKKNLVIGVVSVLSVISLAACGSGNTKTTKKSEGRVTIEYWHV
                     NADTLGGKTVNELVDKYNQSQDKVKVVAKYNPDMYKGLMQNLQASVASKEIPDVVQVG
                     WAFKDYFAENFKYTNPQSLVEEVDPDNADYFKDHFLDNIMALSEKDGKQVGIPYSISN
                     PVLYLNQDILKAAGLDENGPKTWEEVQTFSKIIKEKTGKYGVYIQEPADNWAQQAILE
                     SNGASVIKDGKATFASKDGIAAYELYQRMVKDQTALHTTWEQGVQSFIDGNVAMVYTT
                     IAQRDNIQKNSTFTAKAVESPSWEGKKVKLPAGGAMLAVTSQTDKKKEATWDFLKYLY
                     SVESLAKWTEGTGYLPPRKDVADAQNGLKAFLAENQMMIPAIDQMDKMVSWSSFPGDA
                     GLEAEQKLLDMRDKILSGNSVNETMKATQKEINELLK"
     gene            3099..3971
                     /locus_tag="ACG804_001449"
     CDS             3099..3971
                     /locus_tag="ACG804_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013669610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4832386.1"
                     /translation="MKRYVGYLYLAPAIILLGVFVFYPLIYTIYLSFFDWNMVAPTKE
                     FVGFANYVKVLTDPVFHKVLKNTLSYTVLFVLLSCVFPYITSFLLGIVIEKGQNLYKP
                     LFFIPAVISLVVAGMVFTWILNPVSGPIAVLLGNFGLRLPMWMNLQGWVIAVIAGITA
                     WKVFGYNFIVIFAAIVGIDQEMIEAAKLDRVPIWRIFFTIVLPMSSSTGLYLLVMTIV
                     QGLQYVFTPIKIITRGGPNNGSANVIYYAYQKAFEMYKVGESSAISVLTLLIFAVFLG
                     VIFKFVEKGVYYEN"
     gene            3961..4776
                     /locus_tag="ACG804_001450"
     CDS             3961..4776
                     /locus_tag="ACG804_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4832387.1"
                     /translation="MKIKRWLPHLLFMFIIIIIIYPLLFIMANSFKPLKDAYQTITSL
                     IPQPFTLENFCYLFENLPIIKITRNTFFIATIITVVKLGVAFFAAYSFTYCRIKGKKI
                     WYFIIIGTMFIPFTVAMIPNYLLIAKLNLIDTTWGVIIPQFADAMGIFLLTQTMREIP
                     VSLLDVAALDNIKQTTVMSKIVFPLTRHAITSTGIWFFITSWNEYVWPVLILRTVDNY
                     TLPLAMQTYISSEGGTNFTVAMAISLITMFVPLVLYAIFQKYIIGTFVSAGIK"
     gene            4792..5916
                     /locus_tag="ACG804_001451"
     CDS             4792..5916
                     /locus_tag="ACG804_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4832388.1"
                     /translation="MGETLELRNIGKKYGEHTILKEIDLAVAAGERIVLLGPSGSGKS
                     TLLRMIAGLEKITSGELFLGTQLANKLPCGEREIAMVFQNYALYPHMTVKENIIFALR
                     ANKIKTADIQHRLEEALKMLGLTPYQDRLPKDLSGGQRQRVALARAVVKRSNYFLLDE
                     PLSNLDVRLRLDARKELVKIHQRYKQTFVYVTHDQIEAMTLADRIVLLNEGRIQMIDT
                     PKNVYTKPKNTFTANFIGSPGMNIMPVTYDQGTLKVASQFLTLNPAWQKQLLQVSGSL
                     YLGIRPEHVTFSKETSDLHGQVKYRELLGQSYAYTVKVDGIEMIVLNEKPTWQIGDAV
                     NLRIEPERMHFFDYQTQENLGYPDYFIEERGNSHALFASL"
     gene            5894..6697
                     /locus_tag="ACG804_001452"
     CDS             5894..6697
                     /locus_tag="ACG804_001452"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFS4832389.1"
                     /translation="MRFLHLSDIHFRENYQTNLFTAELFPTIKNPQLALEKLLQELSL
                     TVYDFILLTGDLVHEGGISDYQVLRKMLDQYFPTTPYYFCRGNHDRRSVFFEGMSVES
                     NETGEYIHCTNQNGLRIISLDSAQDTQHEGKISIGQMIQLQEWLGTPAEKGTILLVHH
                     PLSWEDPSIVTEVPEGFAELIAESDILGIFVGHIHQGSSAEFAGKKQFMAESLSFGVD
                     EYPDYSLFTNRTGFTSGSLIDGKIFTYQHYLTPHQIEIGRMKKPITGNH"
     gene            7157..7420
                     /locus_tag="ACG804_001453"
     CDS             7157..7420
                     /locus_tag="ACG804_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HFS4832390.1"
                     /translation="MAKLQISMDEKLKNEAESIIDELGMSPKTAVTVFYKQIVEQGKI
                     PFSIELSEKSKRIHNIQRLAEKLPVQKLDTDEKIEEWFNEDEY"
     gene            7404..7739
                     /locus_tag="ACG804_001454"
     CDS             7404..7739
                     /locus_tag="ACG804_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFS4832391.1"
                     /translation="MKMNTNDIATVYVAFTAAEGGKRRPVYILKNGLDTISFLSITSK
                     YHTKSDKIKLKYVEIRDWKQAGLKKESWIDVGTLNELPKNNKKVKWKKIGELSPSDLQ
                     RLEERMEEL"
     gene            complement(7918..9132)
                     /locus_tag="ACG804_001455"
                     /pseudo
     CDS             complement(7918..9132)
                     /locus_tag="ACG804_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            9333..10607
                     /locus_tag="ACG804_001456"
     CDS             9333..10607
                     /locus_tag="ACG804_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1476 family transposase"
                     /protein_id="HFS4832392.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSP
                     SYCEHCRSVRIIRNGSYTTRTQILKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQAILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQSRMNFLPTVL
                     CMDEFKSMKSVSGSMSFICVDGTTHQLFTILEDRRLYKLTQYFLHFPRKARLKVKYLV
                     MDMNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQIMNRFRTSHSENQKKYR
                     RLKRYWKLLLKDSTTWEPLKRHYHRLFKRPISQTEIVDELLSYNEELRTAYHFCQLLR
                     YYFVKRGTEGFQETLKTISSTLPQSFKKKFTIFHCYQSGISNAFKVSHSNGVTEGLNN
                     KIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
     gene            complement(10990..11718)
                     /locus_tag="ACG804_001457"
     CDS             complement(10990..11718)
                     /locus_tag="ACG804_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4832393.1"
                     /translation="MLRIAIVDDDCTIVEGIRHYLLKKVPDIIIDHCYTDGDEAFKNL
                     QNQRFDLLITDITMGKISGLELIESLQQTSNRYFTSIVISAHQNFQYAKKGIDLSIKS
                     YITKPIDFPYLVKLVQEEKMRKSAANQNSLTDDSFNESIQQVIDYVQNNYSEKLTLKD
                     VATQFHYHPAYLGRAFKKETGYSFHDYLLDFRIKRASALLKDTFLSIDEISQKVGIDH
                     VSYFSVLFKKTTGHSPSNYRKKLL"
     gene            complement(11696..13270)
                     /locus_tag="ACG804_001458"
     CDS             complement(11696..13270)
                     /locus_tag="ACG804_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFS4832394.1"
                     /translation="MKNDLSKVIMRFTYILIFFITLLACFTLFFSYINVIEKEKNQNL
                     QNIQQITHYMETYNRILSGIVTEIYQNYDFQENLNDYYLSSPAEYMEDILSKDRSPTY
                     LVDNLKKLVQDDEVKNISISLDYEKYLSAYAPTKNEKISFIRSLSFISEDMPDATLIL
                     DVSINALKKSLFPTHYNYSLSNGIDSVNLSEDISPSKWKKTQQIAIGNHTLQVYENPN
                     YSSQTLLGLAIMIFLLMSLFILAIHQLLNRSFRNYIQQYQEIITSLNHSSTGDYKSIN
                     IENKVGDLKEIAMHINQFYLDNATYQKTLYENNWLKQEAKYAALQYQIEPHFLFNNLE
                     FIRMTAILNDDEEISDSIYLLSKLYRNNTYQPDIIDLKEELINIDLSLQLHQRRYRHN
                     FDYQLIDHIDQLMLPKLSLQPFVENYIKHGFDSSKKENRLTVYATETTNHYVLKIVEN
                     GKGMDQDKLEHIQQKLNDDIPYSENIGISNSFRRIKHLYPGDTRFVIESQLHVGTTIT
                     IKIQKGGNMHVENCNC"
     gene            13499..14437
                     /locus_tag="ACG804_001459"
     CDS             13499..14437
                     /locus_tag="ACG804_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4832395.1"
                     /translation="MKLKKGLLGNLKKNRALFIMLLPGALWLFIFCYIPMFGVVIAFK
                     DFRISSRGFFTSLFNSPWVGWENFKYLFASQDAWIITRNTVVYNVVGILLSTFCTVSL
                     AIILSQMANKRLLKKMQTFMIFPNFLSWVVISYFVYAFLSTDKGLINILLSNFGVEPI
                     NWYSEPKYWPFIIVFTSLWKGVGYGSIIYYASIMGIDTSYYEAALVDGASKWQQIRNV
                     VLPHLRSIIVIMLILSVGSIFRADFGLFYQLPRNSGALYDVTNVLDTYVYRGLMNSGD
                     IGMSTAAGLYQSSVGFVLILITNKIVNKLDPSSALF"
     gene            14449..15360
                     /locus_tag="ACG804_001460"
     CDS             14449..15360
                     /locus_tag="ACG804_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4832396.1"
                     /translation="MISKLKRQMYFSLPVERFFTILLILFTLSCIFPFIFVIVISLTD
                     EKALQLNGYELLPAQWSTDAYQYLIQDGGQLLRSLGVTIMITVIGTLITVFMTGTYAY
                     VLSRASFPYRKFFTFYLFFTMLFAGGMVPSYLVMTKMLGLKNTIWALILPLAFSPYNV
                     IILRTFFKKSIPESIIESAKMDGCSEFRVFFQIVLPLAIPGVATIGLFSSLGYWNDWF
                     NALLYIDTNKLIPLQYLLMKIQNSMEFLANNNDITLAQQQAIQNSLPQESTRMAMVVV
                     ATLPIAIVYPFFQKYFVQGLTIGGVKE"
     gene            15384..16856
                     /locus_tag="ACG804_001461"
     CDS             15384..16856
                     /locus_tag="ACG804_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFS4832397.1"
                     /translation="MKKNMQKYLIGGASVLTLGLLGACGSSNGEANNETGTTKVTWYQ
                     VGEEPKDFDEVMTKVNEKLKEEINVELDMRLIPDGDYQQKLGVMINSGEEYDICFVNG
                     TDYVNYGNKGAFISLNDHLDKELKDYAAELNEGFIEGGAINGETYGLPVNNDIATTEY
                     WTFNKDLVDQYQLDVENVEGVETLAPVLEKFAEKNTDTNITPIGMTRTSVCIPYDNII
                     GGGVPLAVAFEGDTQTVVNTYETPEMMTYLKAMHEFYKKGYILKDAATVTTDPFRIDS
                     KNWFLGRNSSGYQPLAQKKLEALAGHGLILKPAGKAFKTTGFARVAMHAVSASSKHPE
                     AALKLLNYVNTNQEVADLMVYGIEGKHYDRNEDGSITLTNSDDYYQGAWALVNTYLVS
                     KTSPITEESKKLEEESKKFQNEAPMSPILGFSFDASDFRTEIASVQNIVSQYEVLLSS
                     GTVDPEQYVPELLEKLEKAGLDKIQASAQEQYDEWRKSNK"
     gene            16907..17518
                     /locus_tag="ACG804_001462"
     CDS             16907..17518
                     /locus_tag="ACG804_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFS4832398.1"
                     /translation="MNENKWTKGFNWVFQLLLLNFTYFILICLGFGILGFFPATIALI
                     AGVVNRKKYGLQESVKFMSKIYKKNFVRYNLYCWSATLLLAGNITTIWLCWQQSAPLF
                     YLLSTLLSVITLFLVFAMLNWVVIKSLGLWMMGDRLIDYLLFTATMLPTVVMQGLVLG
                     IYFRILMILPVIFLFGGTAVTVILISKLTERALAKLPCQIQSH"
     gene            17548..19461
                     /locus_tag="ACG804_001463"
     CDS             17548..19461
                     /locus_tag="ACG804_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 20 glycosylhydrolase"
                     /protein_id="HFS4832399.1"
                     /translation="MKLTDKQVANIAFIQQLEIPLTQKDEEQIDLIFTDTKANVRQIK
                     ITKNEQQRICLSYSHEDLLYRGLFICLPRFLAQGGEMPYIEETSIIETSYSLDASRNG
                     VMNKETLKKFISYLALMGYNTLYIYTEDTYEVEDLPYFGYLRGAYTKEEVNEIVEFAS
                     GFGIEVVPSIQTLAHLTQFLKWYAQQELMDDQNTLLIGEEKVYAAIEKMIIACKEMYQ
                     TERIHLGMDEAYQAGLGRYLSLYGYCDRTTLMIQHMDRVLSIVDKYKMKPMIWSDFIY
                     KLLDETGKDRYYNPDFKLKALAAKGLPAGLTYVHWDYGSDEVSSYEKVIDNHLKFCDI
                     DHYVLASGAHIWGRLAPNHGKTEAIVSAAVKASKNKGVRSVMLTTWGDEGQETEHWHS
                     LIGALKLADYVYSEEEWNDFEEIYDRLLGTGSYQLMSELRYFDEVDTITNNNLQMASV
                     SKLLLWQDPLVGIYDFHVAAHNKIATRTIGTYYHELAQKLDMNKNWNPKQPILTTIRQ
                     RYILLAEILAQKAELGIYLQHCCLVEDLAGLMELANRCEALANRVNELASIHEIIWYQ
                     TYKTYGWEVLEQRYAALAHRLKTVARRIKNHLQGQDALEELLEERLPFCQYQVPLEIS
                     GFNYRQSSVSGYN"
     gene            19589..22570
                     /locus_tag="ACG804_001464"
     CDS             19589..22570
                     /locus_tag="ACG804_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 TIM barrel-domain
                     containing protein"
                     /protein_id="HFS4832400.1"
                     /translation="MLSDYYQNLSVISVNTEPLRNYYIPYASKEEAKQELEREKTSQF
                     IDLNGTWDFQYYPSVQQLPENFFQEAFTESYDRISVPGVWQTEGFDLPQYINVSYPIP
                     FDPPYVPNDTPCGVYRRQFQIEQTDARFYLNLEGADSNCFVWINRNFVGYDQVSHSTS
                     EFDVTKYLQVGVNEIQILVMKWCDGTYFEDQDKWRMSGLFRPVYLLQRPTMHLTSYQL
                     RTLTDPKKGSGTLMVSFQRFTPIEVSLPISYELFHPDGRLIAKGECYSEQQINLDVED
                     CLFWTAETPKLYTLLLTCNGEYFKEKVGFRALTIKNRKLLLNGTPIKLYGVNYHDVNQ
                     QGTPVMTREQLRADLLLMKKLNVNTVRTAHYPKSPDFYELADEIGLYVINEADLECHG
                     VVNLYDTEANYQLIANDPTFEKPIMDRVIRSILPYQNRSSIIMWSMGNESGYGVNFEK
                     AQALARKLDDSRLIHNERSIEPVIDQVNDFSNLDVISQMYPPLEDVHRHCQRSDTEKP
                     FFMCEYSHAMGNGPGDLKTYFDLIQQYDSFLGGCVWEWTDHAINRGTLETPSYLYGGD
                     FGEKYHDGNFCVDGLLTPDRQLTVGALEYRNIHSPIQLIAVDEELQEVTLSNITAFTA
                     GSAFNLSLEWYIDGKKTVYEVMNPFILEPGKSCSLPITVPTTIHGAHTVAVSLSVYKN
                     DELYGQQQLFLKKEKMRLPRTAHHNDAPQISVKGTELIIKGESFIYIYQLAKAAFTSV
                     KINQKELLERPTQFSIWRAPTDNDRNLVNKWKAAGYAEMSLEIRKKDWKFVDDHLLIE
                     TSYRGVIPGLQPIFTMHIQLKINGAGVINQKVSVEKNPIFPDFPRFGMDWPLNDTFSK
                     VSYCGYGPYESYPDKHYAAMFGIYEMEIEEFDQPYIKPQEYGNRWQCDWVSIKNHQGS
                     TMTVYGNSNFSALPYSQAQLTEKSHHYELIKENRTWFNLSYKQNGIGSHSCGPYLEDR
                     FRFMEDTFDWNIVITFKGENR"
     gene            22567..24228
                     /locus_tag="ACG804_001465"
     CDS             22567..24228
                     /locus_tag="ACG804_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein O-GlcNAcase"
                     /protein_id="HFS4832401.1"
                     /translation="MKETKINQVKKKLSRYQEVVYRNHCLKWSKNKLNVRFNGLFYRF
                     EQLEEVWKPVTNFQSCPVQLINDPKETYDLCITHLYNQHLKNDGFYLKVTNDNQLTIE
                     SANLRGFQYAMEALLESFFSVGDQLLLPELILKHEPSVKIRGIIEGFYGIPWTHEMRL
                     SLFSYMKDNQLNTFMYAPKDDELLRKKWRELYDAQELDKFKELLSAAEASNIDFWYLI
                     SPGNDIDITCEEDIQVLLKKLEQLIELGVFQFGLLMDDIDYQLKGAAKRRFREPAFAH
                     AYLVNRVEEYLSTRLSNHELVICPTEYDNRHGSRYLATLSQEIPEQLPFFWTGPSTLA
                     ASISTEELQEMASVYQRPMLIWDNIPVNDYLEDKELLFMSPYENRTPNLSKERYQVTG
                     VVSNPMAQLEASKFTINSMANYLWNCERFDPLETWTSVVEKVVGSKLQPAYLTLTNAF
                     PNHYTSSLLSDEELLLAKDPEWVTKEMAALVQAVKWIQQEQHTSRLRTELEPWLQAIT
                     ESWTFWQEWQLKKDPKEAEEWLAKKKTHRIGRDLVTAHLEQIIKS"
     gene            24268..25200
                     /locus_tag="ACG804_001466"
     CDS             24268..25200
                     /locus_tag="ACG804_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HFS4832402.1"
                     /translation="MVKRLISANYSDVKKMTSKELKQSIKASEGRVIVCETVANTLPQ
                     SGEITNAEVASAFGADLILLNGFDCYRPAVFGLPNVTIEKVFDLQQTIENPIPKLKEL
                     VGRPVGINLEPIAPKTNMMSEKVEISQGRASSVETIQKAEELGVDFICFTGNPGTGVT
                     NLEITKSVKMAKKYFSGLIIAGKMHSAGSEEPVVNKEAIISYAEAGADILLVPSVGSI
                     PGFLEQDLIEAVRLAKKYDLLTMSAIGTSQESARPETLRQLAIMNKSCGVDLQHIGDA
                     GYGGLAPAENIFETSVAIRGMRHTINCVSRSINR"
BASE COUNT         8224 a         4109 c         5225 g         7951 t
ORIGIN      
        1 catcacgaga catgtttggg gagatctgat ggatgaagtg gaacatcttc gcctaacaga
       61 tctgaataaa tcaatttaca aaaaacggaa acaaacgatt gaacgaatat ttgcggatgc
      121 aaaagaaaag catgggatgc gttggaccaa gtatcgaggc ttggaaaaag tcgcgacgca
      181 tacgatgcta gtgtttgctg caatgaattt aaagaaatta gccacctggc tatggaaagg
      241 caaggagcct ttattttttt gttcaaaaat tcgaaacgaa gtagataaaa agctgttcca
      301 agctcgagtt acgagtttgg aacagctttt gtctacagtc tggctgtctg tgaggacagc
      361 tttttttgtg ggctaggcat agcaaaaagg ggtagtgaca gtccactggg agggtgcaca
      421 tcgaccaatc gctagagaaa cgcaaggtgg tatttgtgag aagatgacgg aagaaatcct
      481 gtatcaaaga cttggttcaa cgagcagaaa tctgatagta agtctcggtc attcaatggg
      541 aataagccat tgaacacctt gatggtatcc tgtaagaaag aacctcaagg actttcagca
      601 agaagaagga atagctgaaa acaaaaaaag gtgtagtagg ttaaaagcgg ggaatgtaga
      661 actacttaat tggtgaaact agctagaagg gcaaaatcga cgattcatga gttcgtagga
      721 aggagcatgc aagatttaca actagtttac tgaaaaaacg cagggaattt acaagaaatt
      781 aacaagaaat taacgcttca tcggtatagt ggacgtgtgg gagaaaatca cggaattaaa
      841 ggaggggtca aaatgaccat gatcactgca cactctggta gtgacaatac ggaggagaat
      901 agctgggcat ttcttcgctt ttgtttggat cgccagcttt gttttgaagt agatgtgcgt
      961 cagcaaacag atggtacgct aatactagcc catgacaggt aagaagttgt cccagattcg
     1021 gtaacccttg agcaggtgtt tcaagcagtg gccaatgaga aggcaaccat gaccattaac
     1081 tgtgatttaa aagaagaggg attggaaatg gccgtttttt cgctggcaca aacctatcaa
     1141 atctggccac aaattgttct tagtggctat gtacaattat cttgggctgc gatttgggga
     1201 aagcatatat tttataatat tgaaaatcag ttcgaaggga aaaaacttgg ggatattacc
     1261 gaagcagatt tgatcgatac cttacagaaa ttagcctatc aaagcgttca aatcgtcaat
     1321 attcatgaag gatggttaac taagttggcc cgtgaagtgg ggcagcagct aggattgaca
     1381 ttttctgtat ggacagtcaa tgaactagaa acgattgagt accttgcgcg ctgtggtgtt
     1441 tataatataa cctcacgttg tgcatgggcc tatttatgga agaaaggagc acagaataaa
     1501 ctattttata atcaaaacag aggagttaag agatttggag atgggataca tgaccatatg
     1561 ggggctttat tcttagcttg atggatatgt ccagtgaccc tgtaccccga aatgcacaaa
     1621 tttcgaatta tttacagaaa attaactaga aatttacatt ggtagttcat aatatttctt
     1681 gattagaaaa atggccataa agaaattagg aggaagttaa tgttatgtta aagaaaaatc
     1741 ttgttatagg ggttgtgtct gttttaagtg tcatctcttt ggcagcttgt ggtagtggga
     1801 ataccaagac aacaaaaaaa tcggagggtc gtgtaacgat agagtattgg catgttaatg
     1861 cggataccct aggtggaaaa acagtgaatg aattagtaga taaatacaat caatctcaag
     1921 acaaagtgaa ggttgtagca aaatataatc ctgatatgta taaaggcttg atgcaaaatt
     1981 tacaagcttc tgttgcctcc aaagaaatac cggacgtagt acaagtggga tgggctttta
     2041 aagattattt tgcagaaaat ttcaaatata ctaatcctca atctttagta gaagaagtgg
     2101 atccggataa tgctgattat tttaaagatc attttttaga caatatcatg gcactgtctg
     2161 aaaaagatgg taaacaagtg ggtattcctt actccattag taatccggtt ttatatttaa
     2221 atcaagatat attaaaagca gcgggcttgg atgaaaatgg tccaaaaact tgggaagaag
     2281 ttcaaacttt ttctaagata ataaaagaaa aaactggaaa gtatggcgtg tatattcaag
     2341 aacctgctga taattgggca caacaagcaa ttttagaaag taatggggca agtgtaataa
     2401 aagatggcaa agctaccttt gcttctaaag atggtatcgc tgcttatgaa ttatatcaaa
     2461 ggatggtaaa agaccagacg gcattacaca ctacgtggga acaaggtgtg caaagcttta
     2521 ttgatggtaa cgtcgcgatg gtctatacca ctattgctca aagggacaac attcaaaaaa
     2581 atagtacttt tactgctaaa gcagttgagt caccaagttg ggaagggaaa aaagttaaac
     2641 tacctgctgg tggcgcaatg ttagctgtta catcacaaac ggataagaaa aaggaagcaa
     2701 cttgggattt cttaaaatat ctttatagtg ttgaatcttt agctaaatgg acagaaggta
     2761 ctggttattt accaccacgt aaagatgttg cagacgccca aaatggatta aaagctttct
     2821 tagctgaaaa tcagatgatg ataccagcaa ttgatcagat ggataagatg gtcagttgga
     2881 gttcatttcc tggagatgct ggattagaag ctgaacaaaa attgttggat atgcgggata
     2941 aaattttatc aggtaattcc gtcaatgaaa cgatgaaagc tactcaaaag gaaattaatg
     3001 agttactcaa ataagcaaag caagcagacg acagcgcctg taagaaagga aaaacaaggt
     3061 cgtctgcttt tgacataagg atgaggaggc tgtcggaaat gaagcgctat gtaggttatt
     3121 tgtatctggc gccagcaatt attttgttgg gcgtgtttgt tttttatcca ttgatttata
     3181 cgatctattt gagttttttt gactggaata tggtggcccc cactaaagaa tttgttggct
     3241 ttgccaacta tgtaaaggtg ctgactgatc cagtctttca taaagtgttg aagaatactt
     3301 tgtcctatac cgttctattt gtcttgctga gctgtgtgtt cccatatatt acatcctttt
     3361 tattaggaat agttatagaa aaagggcaga atttgtataa accattattt tttattccag
     3421 ctgtgatttc tttggtagtg gcggggatgg tttttacatg gatattaaat ccggtatcgg
     3481 gaccaattgc tgtcttgttg ggaaattttg gtttaagact gcctatgtgg atgaatttac
     3541 aaggttgggt aattgctgtg attgcaggta ttactgcttg gaaagttttt ggttataatt
     3601 tcattgtcat ttttgcagca attgtgggaa ttgatcaaga gatgatcgaa gcagctaagt
     3661 tggatcgtgt acccatctgg cgcatttttt ttacaattgt gttgcctatg agtagttcga
     3721 caggactata tttattggtg atgaccattg ttcaaggtct gcagtatgtg tttactccga
     3781 ttaagatcat cactcgtggt ggaccgaata atggtagtgc aaacgtgatc tattatgctt
     3841 atcaaaaggc ttttgaaatg tataaagtcg gagaatcttc agcaatttca gttttaactt
     3901 tattaatatt tgctgttttc ttaggggtaa tatttaaatt tgtggaaaag ggggtttact
     3961 atgaaaatta aacgctggtt gccacatctc ttatttatgt tcatcataat cattattatc
     4021 tatccattat tgtttattat ggccaattct tttaagccat tgaaagatgc ctatcagacg
     4081 attactagtt tgataccaca gccgtttacc ttggaaaatt tttgctattt gttcgaaaat
     4141 cttccaatta tcaaaattac gagaaatact ttttttattg ctacaattat aacggttgtt
     4201 aagttaggcg tagctttttt tgcggcatat agttttactt attgccgaat caaagggaag
     4261 aaaatctggt actttatcat cattggtacg atgttcattc cttttactgt tgcgatgatt
     4321 cctaattatt tgttgattgc aaaacttaat ttaattgata ctacttgggg tgtgataata
     4381 ccacaatttg ctgatgcgat gggcattttt ttattgacgc aaacaatgcg ggaaattcca
     4441 gtgagccttc tagatgtggc ggcattggat aacatcaaac aaacaaccgt catgagtaaa
     4501 attgtttttc ctcttactag acatgcgatt acttctaccg gtatttggtt ttttattacc
     4561 tcttggaatg agtatgtttg gccggtatta attttacgga cagtagataa ttatactttg
     4621 ccgttggcga tgcagaccta tattagttct gaaggtggga caaattttac cgtagcaatg
     4681 gcgattagtt taattacaat gtttgtaccg ttagtcttgt atgcaatttt tcaaaaatat
     4741 attatcggga cttttgtttc tgcaggtatt aaataaattg gaggacaaat catgggagaa
     4801 acgcttgaat taagaaatat cggaaaaaaa tatggagaac ataccatttt aaaagaaatt
     4861 gatttagctg tggccgctgg agaacgaatt gtgttactgg gaccatctgg ttcaggaaaa
     4921 tctactttgc tgagaatgat tgctggtttg gaaaaaatta cgagtggaga gcttttttta
     4981 ggtacacaac tagcaaataa gctaccttgt ggagaacgag agatcgcaat ggtttttcaa
     5041 aattatgctt tatatcctca catgactgta aaggagaata ttatttttgc attaagggcg
     5101 aataaaatta agacagctga cattcagcac cgtttggaag aagctttgaa gatgttaggt
     5161 ttaacgccat accaagatcg acttcctaaa gatttgtcag gagggcaacg gcagcgtgta
     5221 gcattggctc gtgcggtggt taaacggagt aattattttt tattagatga accgttatca
     5281 aatttggatg tgcgtttacg attggatgca cgaaaagaat tggtaaaaat tcatcaacgt
     5341 tataaacaaa cttttgtcta cgtcactcat gatcaaattg aagcgatgac gttagctgac
     5401 cggattgttt tattgaatga aggtagaatt cagatgattg atacgccgaa aaatgtttat
     5461 acgaaaccta aaaatacttt tactgcaaat tttattggtt cgccaggcat gaatattatg
     5521 ccagttactt atgatcaagg aacattaaag gtagccagtc aatttttaac attgaatcca
     5581 gcttggcaaa aacaacttct tcaggttagt ggctcattgt atttaggcat aagaccagaa
     5641 cacgtaacct tttcaaaaga aacaagcgat ttacacggtc aagtgaagta tcgtgagcta
     5701 ttaggtcaaa gttatgcgta caccgttaaa gtcgatggta tagaaatgat tgtccttaat
     5761 gaaaaaccta cttggcagat tggtgatgca gtcaatctcc gcatagaacc tgaaagaatg
     5821 catttttttg attatcagac gcaagaaaat ttaggatatc ctgattattt tattgaagaa
     5881 agagggaata gccatgcgct ttttgcatct ctctgatatc cattttagag aaaactatca
     5941 aactaacttg tttactgctg aactatttcc aacaattaaa aatccacagt tggcattgga
     6001 aaaattgtta caagaactct cgttaacagt gtacgatttt attctattaa caggtgattt
     6061 agtacatgaa ggggggattt ctgattatca agtcttacgg aaaatgttgg atcaatattt
     6121 cccaaccaca ccttactatt tttgtcgtgg gaatcatgat cgtcgcagtg ttttctttga
     6181 aggaatgagt gttgaaagca atgaaacggg agagtatatc cattgtacga atcaaaatgg
     6241 gttacgaatt atttccttgg attctgctca agatacccag cacgaaggaa aaatatcgat
     6301 aggacagatg attcaattac aagagtggtt gggtacacct gctgaaaagg gaacgatttt
     6361 attggttcat catccattgt cgtgggaaga tccatctatt gtaactgaag ttccggaagg
     6421 ttttgctgaa ttgattgccg aaagtgatat tttaggtatt tttgtaggac atatccatca
     6481 aggtagcagt gctgaatttg ctggtaaaaa acagtttatg gctgaatctt tatcatttgg
     6541 tgtagatgaa tacccagact attctctttt taccaataga acaggattca ctagtggcag
     6601 tttaattgac ggaaaaattt ttacttatca gcattattta actccacatc aaatagaaat
     6661 agggcgcatg aaaaaaccaa ttactggtaa tcattaaaaa ttattgatta aaaataaaga
     6721 cttcattcac tttttagccg tggtgctcaa tgtctggttc cacttgaaga acttggaaaa
     6781 tcgctatcaa taaaccacta tccctccaat tacaaaaagg gtggagaaag ttttccaaga
     6841 accatatcgg tcttcgtggt tgtgccattc gttttttacc agagcatacc acatctttgt
     6901 ggagttttca gacacgtcct agttaatttg gttcttttag gagtcttttc ctgttctgtg
     6961 tgtcgttgag tgttcgcttc aattatcgct gtggcggatt ttgaaacttt tctatctatc
     7021 aaggccattt agcactatat cctttcctta tatttagata aatacactgc atttcaagga
     7081 gttcaaaagt agttgtatta attccatttg aactctttcc gtgatataat gtgtttgtca
     7141 gaaagaggtg gagaaaatgg ctaagttaca aatttctatg gacgaaaaat tgaaaaatga
     7201 agcagaaagc attattgatg aactaggcat gagccccaaa acagccgtca ccgtttttta
     7261 taagcaaatt gttgagcaag gaaaaatccc attttctatt gaattgtcgg aaaaaagtaa
     7321 acgaatccat aatattcaaa gattagcgga aaaattgcct gtccaaaaac tagacactga
     7381 cgaaaaaatt gaagaatggt tcaatgaaga tgaatactaa tgatatagca accgtctacg
     7441 ttgctttcac agctgcagag ggcggtaaac gccggcctgt ctatattcta aaaaatggac
     7501 tggacacaat ttcgtttctg tcaattactt caaaatatca tactaaatcc gataaaataa
     7561 agctgaaata cgttgaaata agggattgga aacaggcagg actaaaaaaa gaatcttgga
     7621 ttgacgtagg aactctaaac gaattaccca aaaacaacaa aaaggtcaaa tggaaaaaaa
     7681 ttggggaatt aagtccaagc gatttacagc gactggaaga acgcatggaa gaattataat
     7741 aatactaaaa agaagggctc tttgtcaata aggactgatg ggttgtacaa aatcaaatct
     7801 gggtcagaat gaacctcatt ctggctcaga tttttggctc tttgtcaata aggactgatg
     7861 agttgtgcaa aatcaaatcc gggtcagaat gaaccacatt ctggttcaga ttttttgtta
     7921 tcttacattg attaattgat tgatcaaaaa gattctaatt ctcatgttct cgaatgattt
     7981 aaatccgtag gatactcgtt tcattgtctt tatgtgggta ttcttcgctt caatttttcc
     8041 attggaataa ggatagatca ttgcgctggt gataccttct tcataggtca gaaggttttg
     8101 aagcttctcc cgaaagccgt catctaacgt ttcgggaagt tctgccaata aggagaaaaa
     8161 taagtcaggg tctttgtctc gaaaggcttc gactaattca tgaaaaaagg gatacgcctc
     8221 ctttagaggc gcagaaaact caagcaatcg atcaatcatc attgcttcag tgagaaatgg
     8281 gtattttggt gctcggaaac ttttccatgt tttgtactca taatggttga tgcttgcacg
     8341 attttttagc agaaagcgcc agttcttttt cagtttttct gcctgacttt tctgtcctgc
     8401 tttacgaagc tcattcattt cacggatacg caactcattg agtgcctgat tcatgtgttt
     8461 gacaatatga aaccgatcaa tcactacttt cgcatttggc agaacacgtt tggtaagctg
     8521 gaagtaagcg gcgttcatgt ctgtgactaa gaattctact tcttctggat tggtgcagcc
     8581 taagaaatag cttgttaatc gaggtaattt acgcgtaggc aagacagcaa ttaagtttcc
     8641 tgtttcacca tctgcgcaaa taaagctcat tttatcttct atggaagcgt gcgaacgaaa
     8701 ttcatcaacc atcaatactc tggggagaat cttcttagaa ggctttggta aatagctttt
     8761 aaactctttc aatgtacgag taacggtagt caaagatacc tgacaacttt tcgcaataaa
     8821 agacaaagat actttttcag tcagtaaaga agcaatttta tatcgaacat gatctgcgat
     8881 tgaatggctg agtcggacaa aataactttg agccgtccaa tgggtacgac agtttttaca
     8941 ggtatagcgt tgctttttta ggcgcgtaac caaaggcata tgattgtatt gttcaaaacg
     9001 gacaatcgtt tccttcttcc catttttcac tataattgct ttcccgtttc catctaccac
     9061 agtagaacca caacttctac aagcacgagg agtaggcgag agaacagcat cgacgaccaa
     9121 cgtctttttc ttggctcttt gtcaaatagg actgatagag tgatataaga acatctaagg
     9181 tagaattgat tttgcttcta taatattttg tgttggtgga aaatcgaagg cgattttcta
     9241 ctaacacttt ttcttcgttt caactcaaaa agagactcac ttttggtaaa atttagtcga
     9301 ccaaaacgtc atcctaccaa aggagtctct caatggataa tcatactaga aaattactcg
     9361 gattaacaga taaacattta ttttttgatg aagaatggct gattgaaaaa gaatataaag
     9421 gcgttcaagc gcagtttatt aaaggaaaat tggatgactc tccttcctat tgtgaacact
     9481 gtcgatcggt tcgtattatc cgcaacggtt cctatacgac acgcactcag atattgaaag
     9541 tcaaagaaaa gttaactatt ttagaattaa aacgtacccg ttttctctgc catgattgtg
     9601 gaaggacctt ttctgcgaaa acggacttag ttgatgaaca tcatcaacta acaaaggaac
     9661 tgaagcaggc aattctcatg gaactgtacg aaaatcaatc acgtaaacta atcgctaaga
     9721 agtacttcgt ctcggatggg acggtgacac ggatcttgcg tgaagcaacg aagcattacc
     9781 agtcacgtat gaacttcctt ccgacggtgt tgtgtatgga tgagttcaaa tcaatgaagt
     9841 ctgtttctgg ttccatgagt tttatttgtg ttgatgggac aacccatcag ctatttacga
     9901 tccttgaaga tcgcagactt tacaaactaa ctcaatactt cctgcacttt cctagaaaag
     9961 cccgtttaaa ggtcaagtac ctagtgatgg acatgaatgc cagctattgt cagttgctta
    10021 aaacagtctt tccaaatgcg gagatcgtaa ctgaccgctt tcatattgtc caacacatca
    10081 atcgcagctt caatcaatta cgtgtccaga tcatgaatcg ttttcgaacc tcacactctg
    10141 aaaatcagaa gaagtaccgt cggctcaagc gatattggaa actcttactc aaagattcca
    10201 cgacatggga gccactcaaa cggcattatc atcgactgtt taaacgacca attagtcaaa
    10261 cagaaatcgt tgatgagctg ttaagctaca acgaagaatt gcgaactgcg tatcattttt
    10321 gtcaattatt acgctattat ttcgttaaac gaggtacgga aggctttcaa gaaaccctta
    10381 aaacaatttc atctacgtta cctcagtcgt ttaaaaagaa attcacgatc ttccattgct
    10441 accaatcggg tatttcaaat gcctttaagg tgtcccactc aaacggcgtc actgaggggc
    10501 tgaataacaa gatcaagctg attaaacgaa ttgcgtttgg ttatcgcaac ttttataact
    10561 ttcgggcacg gatctattta caacaaggtc tgatctttga aaactaaaaa aatatgcggc
    10621 gcacagaacg cgccgcatat cggactaagt tttattcaaa tttgtcttca ccaacacgat
    10681 ttgacgaaga gcctatttaa ataactacat ccatttattc tatcttctaa aatagccttt
    10741 ttcatttcag ttaaatagtt cagcgccatt tttgcactcg acttgcatag tagttttttc
    10801 catattcctc aacctcagcg ggggttgaag acataaggaa aatcctatgc gttatgctca
    10861 actggatctg attaaatatt ctaatgtatt tttctctacc atcattaaat ggttaatagc
    10921 caaaaatcac cacttttcaa tggctccttg ttgtataagt ataactagaa gatgaacacg
    10981 tctgagaaat tatagaagct ttttacggta attactgggg ctgtgtccag tagttttttt
    11041 gaagagaaca gaaaaatagc tcacgtgatc tattcctact ttttgactaa tttcatcaat
    11101 agataagaat gtgtctttca gtagagcact tgctcttttg attcgaaagt ctagcaagta
    11161 atcatgaaag gaataacctg tttctttttt gaaggcccgt cctaaataag cgggatggta
    11221 atggaattgt gtagctacat ctttgagcgt aagcttttca ctataattgt tttgaacgta
    11281 atcaatcact tgttgaattg actcattaaa agaatcatca gttagagagt tttgattagc
    11341 tgctgattta cgcatttttt cttcttgtac taacttaact aaataaggaa aatcaatggg
    11401 tttcgttatg taacttttaa tagataaatc aatccccttt tttgcatact gaaaattttg
    11461 gtgggcacta atgacaatac tagtaaagta gcgattggat gtttgttgca aagattcgat
    11521 taattcgagt ccagaaattt tccccatcgt aatatctgtg ataagtaaat caaagcgctg
    11581 gttttgcagg tttttaaatg cttcgtctcc gtctgtgtag cagtgatcga taatgatgtc
    11641 ggggactttc ttcaaaagat aatgccttat gccttctaca attgtacaat catcgtcaac
    11701 aattgcaatt ctcaacatgc atattccccc ctttttgtat tttgatagta atcgttgttc
    11761 cgacgtgtag ttggctttct ataacaaaac gtgtatctcc aggatagaga tgctttatac
    11821 gtcgaaaaga atttgagatg ccgatattct cactataagg aatatcatca ttaagttttt
    11881 gttgaatatg ctccagcttg tcttggtcca ttcctttccc attttcaacg atttttaaca
    11941 cataatggtt ggttgtttca gttgcataga cagtcaaacg attttccttt tttgatgaat
    12001 cgaagccgtg tttaatataa ttttcaacaa atggctgtaa agaaagtttt ggtaacatta
    12061 attgatcaat atgatcaatc agctgatagt caaagttatg tcgataacga cgttgatgta
    12121 gttgcaagga gaggtcgata ttaattaatt cctctttcaa atcaattatg tcgggctgat
    12181 atgtattatt gcgatacaac ttgctcaata aatatatact gtcgctgatt tcttcgtcat
    12241 cattcaatat ggcagtcatt cgaataaatt ccaaattatt aaatagaaaa tgaggctcga
    12301 tttgatattg aagtgctgca tactttgctt cttgcttcaa ccaattattt tcataaagtg
    12361 ttttttgata tgtagcatta tctaaataaa actgattgat atgcatagcg atttctttca
    12421 aatcaccgac tttgttttcg atattgattg acttgtagtc tcctgtagat gaatgattta
    12481 aggaagtaat gatttcctga tactgctgga tatagttacg aaaacttcta tttaataatt
    12541 gatgaatagc aagaataaac aaactcatta ataagaaaat catgattgcc agacctaata
    12601 aggtttgtga cgaataattt ggattttcat atacttgtaa tgtgtggtta ccgatagcta
    12661 tctgttgcgt ttttttccat ttagaaggcg agatgtcttc agataaattg acggaatcaa
    12721 taccattaga caaagaataa ttgtaatgtg ttggaaagag actctttttt agcgcgttga
    12781 tcgaaacgtc tagaatcaat gtagcatcgg gcatgtcctc actaatgaaa cttaatgaac
    12841 gaataaaaga aattttttcg ttttttgtag gtgcgtaggc acttaagtat ttttcgtaat
    12901 ctaatgagat agatatattt ttaacttcat catcttgcac aagttttttt aagttatcta
    12961 ctaaataggt aggggagcga tcctttgaca aaatatcttc catgtattca gcaggtgatg
    13021 agaggtagta gtcattaagg ttttcttgga aatcataatt ttgatagatc tctgtcacga
    13081 taccggagag aatacgatta tatgtttcca tatagtgggt gatttgctga atgttttgca
    13141 ggttttgatt tttttctttt tcaatcacat tgatatagga aaagaacaat gtgaaacagg
    13201 caagtaaagt aataaaaaaa atcaatatgt atgtaaaacg cataataact tttgataaat
    13261 cgtttttcat tcaaagtcct cattttgata atctctaatt ttatgaatca ttatagcaca
    13321 tattacaagt gatgtaaacg ctttgcaaac agggctactt atgattgtga atacagtttc
    13381 cgtttaaaaa ctattctatt gtagaggttt aataaactaa aaataatgta taaaaaatta
    13441 atgtaagcga ttaaccaagt gggtataatc aaggaaacgc tgagagagga gagacaaaat
    13501 gaagctaaag aaagggttat taggaaatct aaaaaaaaac cgagcattgt ttattatgct
    13561 tttaccaggt gcgttatggt tatttatatt ttgctatata ccaatgtttg gagttgtaat
    13621 cgcttttaaa gatttcagaa tttcatcaag gggattcttt acaagtttgt tcaacagtcc
    13681 ttgggttggc tgggaaaatt tcaaatatct ctttgcttcg caagatgctt ggatcattac
    13741 tcgcaatacg gttgtttata acgttgtagg tattttgcta agtacttttt gtacagtgtc
    13801 attagcaatc attctgagcc aaatggcgaa caaacggtta ttgaaaaaga tgcagacatt
    13861 tatgattttt cctaattttt tatcatgggt agtcatcagt tactttgttt acgcattttt
    13921 gagtacggat aaaggattaa ttaatatttt actaagcaat tttggtgtgg aacccataaa
    13981 ttggtatagt gaaccgaagt actggccttt tattattgtt tttacgagtt tatggaaagg
    14041 cgtaggctat ggatccatca tttattacgc gtcaattatg gggatcgata ctagttatta
    14101 tgaagctgct ttagttgatg gtgccagtaa atggcaacag ataaggaatg tagtcttgcc
    14161 acatttaaga tcgattattg tcattatgtt gattttgtct gttggtagta tttttcgagc
    14221 tgattttgga ttgttttatc aattgccaag aaattcgggg gctctttatg atgtgacgaa
    14281 tgtattagat acttatgtct accgtggatt aatgaatagc ggagatatcg gaatgtctac
    14341 ggcagcggga ttatatcagt catcagttgg ctttgtcttg attttgatta ctaataagat
    14401 agtcaacaag ttagatccta gttcagcact attttaggag gaatcaaaat gatatcaaaa
    14461 ttaaaacggc agatgtactt ttcgctgcca gtcgaacggt ttttcacaat attactaatc
    14521 ttatttactc ttagctgtat ttttcccttt attttcgtaa tcgtcatttc attaacagat
    14581 gaaaaagcat tacaactcaa cggttacgaa ttattgccgg ctcaatggag cactgatgca
    14641 tatcaatact taatacaaga tggcggacag ttacttcggt cattaggcgt tacaattatg
    14701 attacagtga ttggaacgtt gattactgtt tttatgacgg gaacctatgc ttatgtttta
    14761 tcaagagcct ctttccctta ccggaagttc tttacttttt atcttttttt taccatgtta
    14821 tttgcgggag ggatggttcc ttcttactta gtgatgacga agatgcttgg cttaaaaaat
    14881 acaatttggg ctttgattct acctcttgct tttagcccat acaatgtcat tattttaagg
    14941 acattcttta agaagtcgat tccagaatcg attatcgaat ccgctaaaat ggatggctgt
    15001 agtgagtttc gagttttttt ccaaatcgtt ttgcctttag cgatcccagg ggttgcaaca
    15061 ataggtttat tttcaagctt aggttattgg aatgactggt tcaacgcatt gctgtatatt
    15121 gacaccaaca aattgattcc attgcaatat ttgttaatga agattcaaaa ttcaatggaa
    15181 ttcttagcaa ataataatga cattacatta gcgcagcaac aagcaattca aaatagcctt
    15241 cctcaagaat caacacgaat ggcaatggtc gtagtagcta ctttaccgat tgcaattgtt
    15301 tatccgttct tccaaaaata ctttgttcaa ggattgacga tcggtggagt gaaagaataa
    15361 aaaagaatag gagatgttaa aagatgaaaa agaacatgca gaaatatttg attggtggtg
    15421 cttctgtact aacccttggc ctattaggtg cttgtggtag cagtaatggc gaagcaaata
    15481 atgaaacagg aaccacaaaa gttacttggt atcaggttgg agaagaaccc aaagattttg
    15541 atgaggtcat gacaaaagtc aacgaaaaat taaaggaaga aatcaatgta gagttggata
    15601 tgcggctgat tccggacggg gattatcagc aaaagcttgg tgtgatgatc aattcaggag
    15661 aagaatatga tatttgtttc gtcaatggca cagattatgt gaattatggg aacaaaggtg
    15721 ctttcattag tctcaacgat catttggata aagagttgaa agattatgca gctgaattga
    15781 atgaaggatt tattgaaggt ggggcaatta atggcgaaac ttatggattg ccagtcaata
    15841 acgatattgc cacaacggaa tattggacct ttaataaaga tttggtagat caataccaat
    15901 tggatgtaga gaatgttgaa ggtgtagaaa cattggctcc agtattagaa aagtttgcag
    15961 aaaaaaatac tgatacgaat attacgccaa tcggtatgac ccgtaccagt gtctgtattc
    16021 cttatgacaa tattatcggt ggtggtgtac cgctagcggt tgcatttgaa ggcgatacac
    16081 aaacagttgt taatacttat gagactccag aaatgatgac ttatttgaag gctatgcatg
    16141 agttttataa aaaaggatat attttgaaag atgcagccac tgttacgaca gatccatttc
    16201 gaattgatag taaaaactgg tttttaggtc gtaactcaag tggttatcaa ccattagcac
    16261 aaaaaaaatt agaagctcta gcgggacatg gattaatttt aaaaccagct ggaaaagctt
    16321 ttaaaacgac tggatttgca agagtggcaa tgcatgcggt atctgcttca agtaaacatc
    16381 cggaagcagc cttgaaattg ttgaattatg tgaataccaa tcaagaagta gcggatttaa
    16441 tggtttatgg aattgaagga aaacactatg atcgcaatga agatggttcg attactttaa
    16501 caaactctga tgattattat caaggcgctt gggcattggt aaatacttat ctagtttcaa
    16561 aaacttcacc gattacagaa gaaagtaaaa aactagaaga agaaagtaaa aagtttcaaa
    16621 atgaagcacc gatgtctcct attttaggtt tctcttttga cgcttctgat tttcgaacag
    16681 aaattgcaag tgtacaaaat atcgtgtcac aatatgaagt acttttaagc tcgggaacag
    16741 ttgaccctga acaatatgta ccagagttgt tagaaaaact agaaaaagct ggattggata
    16801 aaattcaggc atctgctcaa gaacaatacg atgaatggcg aaaatctaac aaataatttt
    16861 ttactaaatg aaaagaatag actaagcagt tagtgggggg attcaaatga acgaaaacaa
    16921 atggaccaaa ggatttaatt gggtttttca attgttgtta ctaaacttta cttattttat
    16981 actaatttgt ttaggatttg gaattttagg ttttttccct gctacgatag ctttgattgc
    17041 tggcgttgtg aatcgaaaaa aatatggctt gcaagagtct gtgaagttca tgagtaaaat
    17101 ctataagaaa aattttgtta gatataatct atattgctgg tcagcaactt tgttgttggc
    17161 cggcaatatt actacgatct ggctttgttg gcagcaaagc gcaccattgt tttatttatt
    17221 aagtacatta ttatcggtaa ttacactgtt cctagtcttt gcaatgttga attgggtcgt
    17281 gatcaaaagt cttgggttgt ggatgatggg agaccgactg attgactatt tgcttttcac
    17341 agcaacgatg ttgccaacgg tagtcatgca aggcttggtg cttggaattt atttccgaat
    17401 attgatgatt ttgcctgtga tttttctgtt tggcggaaca gctgtaacgg taatattgat
    17461 tagtaaatta actgaaagag cgttagcaaa gttgccttgt cagatacaat cgcactaatt
    17521 ttttcacaaa aaggagtatt tctttctatg aagttaactg ataaacaagt agctaatata
    17581 gcctttatcc agcaacttga gattccattg acacaaaaag atgaagaaca aatagacttg
    17641 atttttactg acacaaaggc taatgtgcga caaatcaaga ttactaaaaa tgagcagcaa
    17701 cgaatttgct tgtcttattc acatgaagac ttgctgtatc gaggattgtt tatctgcctt
    17761 ccacgttttt tagctcaagg aggagagatg ccatacattg aagaaacctc gatcattgag
    17821 accagttatt cattagatgc ttctcgtaat ggcgtgatga ataaagagac tctaaaaaaa
    17881 ttcatttctt acttagcgtt gatggggtac aacacattgt atatttacac agaagatacc
    17941 tatgaagtag aagaccttcc atattttggt taccttcgcg gagcgtatac aaaagaagaa
    18001 gtgaatgaaa ttgttgaatt tgcttctggt tttggcatag aagtagttcc atcgatccag
    18061 acccttgctc acttgaccca atttttgaag tggtatgctc aacaagaact gatggatgat
    18121 caaaatactc tactgatcgg tgaagaaaag gtttatgcgg caatcgaaaa gatgattatt
    18181 gcctgcaaag aaatgtatca gacagagcgt attcatttgg gaatggatga agcctatcaa
    18241 gcaggtctgg gacgatattt aagcctgtat gggtattgtg atcggacaac tttaatgatt
    18301 caacatatgg accgtgtgtt atcaattgtt gataaatata agatgaaacc aatgatttgg
    18361 agtgatttca tttataagct attagatgaa accggtaaag ataggtatta caatcctgat
    18421 tttaaactca aagcattagc agctaaagga ttaccagcag gattaaccta tgttcattgg
    18481 gactatggtt cagatgaagt ttcctcctat gagaaagtaa ttgataacca tttgaaattt
    18541 tgtgacattg atcattacgt tttagctagt ggtgcccata tctgggggag actagccccg
    18601 aatcatggga aaacagaagc aattgtttct gcagctgtaa aagcttctaa aaataaaggt
    18661 gtacgttctg tgatgttaac tacttgggga gatgaagggc aggaaacaga gcattggcat
    18721 tccttaattg gggcattaaa attagcagat tatgtctatt ctgaagaaga gtggaatgat
    18781 tttgaggaaa tctacgatcg tttattagga acaggtagtt atcaattaat gtccgaatta
    18841 cgatatttcg atgaagtgga taccattaca aataacaact tacaaatggc ttccgtgagt
    18901 aaactgctac tttggcaaga tccgttagtt ggtatatatg actttcatgt agccgctcat
    18961 aacaaaattg ccactagaac aattggtact tattatcatg agttagctca gaaattagat
    19021 atgaataaaa attggaatcc aaaacaacca attttaacaa ctattcgtca acgatatata
    19081 cttttagctg aaattttagc acaaaaggca gaactaggca tctatttaca acactgctgt
    19141 ctggtagaag accttgcagg attaatggaa ttagcgaatc ggtgtgaagc actagccaat
    19201 cgagtaaatg aattggcatc tattcatgaa ataatttggt atcaaacata caaaacctat
    19261 ggttgggaag tattagaaca acgatatgct gcattagctc atcgtctgaa aaccgttgcg
    19321 cgtcgtatta aaaatcatct tcaggggcaa gatgccctag aggagctttt ggaagaacga
    19381 ttaccgtttt gtcaatatca agtgccgctt gaaatttctg gctttaatta tcggcaaagc
    19441 tcggtgtcag gctacaatta acgaaggaat cttcccgttg aacggaccac ttgctcatct
    19501 aatgggaaag tggttcgttt tctattcata agtagcttac cactaactct tttattaaga
    19561 agagaaaaaa agtaggaagt gagaaaatat gttatcggac tattatcaaa atctgtcagt
    19621 tataagtgtc aatacagaac cattacgtaa ttattatatt ccttatgcaa gtaaagaaga
    19681 agcaaaacaa gagttagaaa gggaaaaaac gagccagttt atcgatctca atggtacatg
    19741 ggattttcag tattatcctt ctgtccaaca gttaccggaa aatttttttc aagaggcctt
    19801 tactgaaagc tatgatagaa tttctgttcc tggagtttgg caaacagagg gatttgactt
    19861 acctcagtat atcaatgtat cttatccaat tccttttgat ccgccttatg tacctaatga
    19921 taccccttgt ggtgtatatc ggcgtcagtt tcaaattgag caaacagatg cacgctttta
    19981 cttaaatcta gaaggagcag atagtaattg ttttgtttgg ataaatagaa actttgtagg
    20041 ctatgaccaa gtgagtcata gtacatctga atttgatgtg accaagtatt tacaggttgg
    20101 ggttaatgaa attcaaattc tagtgatgaa gtggtgtgat ggtacctact ttgaagatca
    20161 ggataagtgg cgaatgagcg gtctatttcg tccagtgtat cttcttcaac gaccaactat
    20221 gcatctgaca agttatcaac tacggacgtt gactgatcct aaaaaaggaa gcggaacatt
    20281 aatggtttct tttcaacgat ttactcctat tgaagtatcg ttacctattt cttacgaatt
    20341 attccatcct gatggacgtc tcatagcgaa aggggagtgt tactcggaac aacaaataaa
    20401 tttggatgtt gaagattgcc ttttttggac agcagaaacg cctaaattat atacattact
    20461 tttaacatgt aatggtgaat attttaaaga aaaagttggc tttcgagcac tgacgatcaa
    20521 gaatcgtaag ttattgctga acggaacacc tattaaatta tatggagtca actatcatga
    20581 cgtgaatcag caaggcacgc cagtgatgac ccgagagcag ttacgtgcag atttgttatt
    20641 aatgaaaaaa ttaaatgtga atactgtacg aacggcacat taccctaaat caccagattt
    20701 ttatgaattg gcggatgaga ttggtctgta tgtaatcaat gaagcagatt tggagtgtca
    20761 tggtgtggtt aatctatatg atactgaagc gaattatcaa ctaattgcta atgatccgac
    20821 attcgaaaag ccgattatgg accgagtgat ccgttctatt cttccttatc aaaatcgaag
    20881 ctctatcatt atgtggtcta tggggaatga atctggttat ggagtaaatt ttgaaaaagc
    20941 tcaagcttta gcacggaaat tggatgattc acggttgatt cataatgaac gctcgattga
    21001 accagttatt gaccaagtga atgattttag taacttggat gttattagtc aaatgtatcc
    21061 cccactggaa gatgttcatc gtcattgtca aagaagtgat actgaaaaac ctttttttat
    21121 gtgtgaatat agccacgcta tgggcaacgg tcctggagat cttaaaacgt acttcgattt
    21181 gattcaacag tatgattcct ttcttggcgg ttgtgtctgg gagtggactg atcatgcaat
    21241 caatagagga actttagaaa cgccatctta tttatacggt ggtgattttg gtgaaaaata
    21301 tcacgacggc aatttttgcg tagatggttt attgacccca gatcggcaat taacagtagg
    21361 tgcattggag taccgtaata ttcattcgcc tattcaactg attgctgtag atgaggagct
    21421 gcaagaagta accttgagca atataactgc ttttacagcc ggttcagcat ttaacctttc
    21481 tcttgaatgg tatatagatg gaaaaaaaac agtttatgaa gtaatgaatc ctttcatact
    21541 tgagcctggc aaaagttgtt cattgcccat cacagtacct acaacgattc atggtgctca
    21601 tacggttgct gtttcgctat ctgtttataa aaatgatgag ctttatggac agcaacagct
    21661 ctttcttaaa aaagaaaaaa tgagattgcc aagaactgct catcataatg atgcaccaca
    21721 aatttcagta aaaggcacag agctgataat caaaggagaa tcctttattt atatatatca
    21781 attagcaaaa gctgcgttca cttctgtaaa gatcaatcaa aaggaacttt tggaacgtcc
    21841 tactcaattt tcaatttggc gtgcaccaac ggataatgat cgtaacttag taaacaaatg
    21901 gaaagcagct ggatatgctg aaatgtcttt agaaatcaga aaaaaagact ggaaattcgt
    21961 agatgatcat ctcctgatcg aaacgtctta tcgaggagtt attccaggat tacagccaat
    22021 ttttacaatg cacatacagt tgaaaataaa tggtgcaggc gtaatcaacc aaaaagtatc
    22081 agtggagaaa aatccgattt ttccagattt ccctcgcttt gggatggact ggccgttgaa
    22141 tgatactttt tcgaaggttt cttattgtgg ctatgggccg tatgaaagtt atcctgataa
    22201 gcactatgct gcgatgtttg gtatttatga gatggagatt gaggaatttg atcagccata
    22261 tatcaaacca caagaatatg gtaaccgctg gcaatgtgat tgggtatcaa tcaaaaatca
    22321 tcaaggatct accatgacgg tttatggaaa ctctaatttt tctgctctgc cttatagtca
    22381 agctcaatta accgaaaagt cacaccatta tgaattaata aaagaaaata gaacttggtt
    22441 caatttaagt tataaacaaa atggtatcgg ctcacacagt tgcggtcctt atttagaaga
    22501 tcgtttccgt tttatggaag atacttttga ctggaatata gtgattactt tcaaaggaga
    22561 aaatagatga aagaaacaaa gatcaatcaa gtcaaaaaaa aattatctcg ttatcaagaa
    22621 gttgtttatc gaaaccattg cttaaaatgg tcaaaaaata agctgaatgt tcgttttaat
    22681 ggattatttt atcgtttcga acagttagaa gaagtctgga aaccggtaac gaatttccaa
    22741 tcatgtcctg tacagctcat aaatgatcca aaagaaacat acgatttatg tataacacac
    22801 ctttataacc agcatttgaa aaatgacgga ttttatttaa aggttactaa tgacaatcaa
    22861 cttacgattg aatcagcaaa ccttcgaggg tttcaatatg ctatggaagc cttattagag
    22921 agtttttttt cggtaggaga tcaattatta ttaccggaat tgattctgaa acatgaacca
    22981 tcagtgaaaa ttcgaggaat cattgaaggg ttttatggta tcccctggac acatgaaatg
    23041 cgcctctctc ttttttcata tatgaaagat aaccaattga atacttttat gtatgcccct
    23101 aaagatgatg aattattacg taaaaaatgg cgtgaactct acgatgcgca agaattagac
    23161 aaatttaagg agcttttatc tgctgctgag gctagcaata tcgatttttg gtacttaatt
    23221 agtcctggaa atgatattga tattacgtgt gaagaagaca ttcaagttct tctgaaaaag
    23281 ttagaacaac tgattgagct tggcgtattt caatttggtc tattaatgga tgatattgac
    23341 tatcaattaa aaggtgctgc taaacgccgt tttcgagagc cagcattcgc tcatgcctat
    23401 ttagtgaatc gagtagagga atatcttagc actcggttgt ccaatcatga attagtcatt
    23461 tgtcctacag aatatgataa tcgtcatggt tctcgctatt tagcaacgtt aagtcaagaa
    23521 ataccagaac aattaccgtt cttttggact ggcccaagca cgttagcggc gtcaatttct
    23581 acagaagagc tgcaggaaat ggcttctgtc tatcaacggc cgatgctgat ttgggataat
    23641 attccggtaa atgattattt agaggataaa gaactattgt tcatgagtcc atatgagaat
    23701 cgaacaccga atctttctaa ggagagatac caggttacag gagtagtttc gaatccaatg
    23761 gctcaattag aagcttcaaa gtttacgatc aatagtatgg ctaattactt atggaactgt
    23821 gagcgttttg atcctttgga aacttggacg tcagtcgttg aaaaagtagt tggaagtaaa
    23881 ctacaaccag cttatcttac cttaaccaat gcttttccaa atcattacac aagcagtctg
    23941 ctttcagatg aagaattact gctagccaaa gacccagaat gggtcacaaa agaaatggct
    24001 gctttagtcc aagcagtaaa atggatccag caagaacaac atacatctag attgagaaca
    24061 gaattggagc cttggttaca agcaatcaca gaaagttgga ctttctggca agaatggcaa
    24121 ttaaaaaaag atccaaaaga agcagaagaa tggttggcta agaaaaaaac acaccgcata
    24181 ggacgtgatt tagtaactgc ccatttagag caaattatca aaagttagat atcttaaaaa
    24241 ataaaaagca agaaaaagga gaacaaaatg gtcaagagat taattagtgc aaactacagt
    24301 gatgtcaaga aaatgacgtc aaaagagttg aagcaatcca tcaaagcgag tgaaggacgg
    24361 gtgattgttt gtgaaacggt tgctaatact cttccacaat ctggagaaat tacgaatgca
    24421 gaagttgcgt cagcatttgg tgcagatttg attcttttaa atggtttcga ttgttatcgt
    24481 cctgcagttt ttggactacc aaatgtgacg attgagaagg tttttgatct acagcaaacg
    24541 attgaaaacc cgattcctaa attaaaagaa ctagtcggtc gtcctgtggg aattaattta
    24601 gaacccattg cccctaaaac aaatatgatg agtgagaaag tagaaatcag ccaaggaaga
    24661 gcaagctctg ttgaaacgat acaaaaagca gaagaactag gagtcgattt tatttgcttt
    24721 accggtaatc caggcactgg agtaaccaat ttagaaatta ctaaatccgt aaaaatggca
    24781 aaaaagtatt tttcgggatt gattattgct gggaaaatgc atagcgccgg ctcagaagag
    24841 ccagttgtga ataaagaggc gattatttct tatgcggaag caggcgcaga tattttacta
    24901 gttccttcag tagggtctat cccaggcttt ttagagcaag acctaattga agcggttcgg
    24961 ttggcaaaaa aatatgattt gttaacgatg tctgcaatcg gtactagtca ggaaagtgcc
    25021 cgaccagaaa cattgcggca attagccatt atgaataaaa gttgtggtgt tgatttacaa
    25081 catattggag atgctggata cgggggattg gcaccagcag aaaatatttt cgaaacctcg
    25141 gttgcaatta gaggaatgcg acataccatc aactgcgtta gccgctcgat caatcgctaa
    25201 caaaattaaa taaaaaatgg ttaaattgat tatttaagtg ggaacatact tgagatatca
    25261 gctaacttct gtcactttaa aaaagggact gtgacagaag tgaaaataga caaaaaatat
    25321 ccgaacaaga gactaggata gcagaaaaac tatcgttttg caacgaggac caactggacc
    25381 gtaggagcaa ttctcttatt gttcggatat ttcgcttgtt caaggactta tgtctgtagt
    25441 gccctttttt ggtaggaaaa atggtaggga accatatcat ttttaatgaa aatcaagcat
    25501 ttcaaaagt
//
LOCUS       DAZUJR010000038        25460 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.038, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000038 DAZUJR010000000
VERSION     DAZUJR010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25460
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.038"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            133..3660
                     /locus_tag="ACG804_001467"
     CDS             133..3660
                     /locus_tag="ACG804_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HFS4832403.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3657..7379
                     /gene="addA"
                     /locus_tag="ACG804_001468"
     CDS             3657..7379
                     /gene="addA"
                     /locus_tag="ACG804_001468"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HFS4832404.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7448..7789
                     /locus_tag="ACG804_001469"
     CDS             7448..7789
                     /locus_tag="ACG804_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFS4832405.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8098..9141
                     /gene="pheS"
                     /locus_tag="ACG804_001470"
     CDS             8098..9141
                     /gene="pheS"
                     /locus_tag="ACG804_001470"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HFS4832406.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9146..11566
                     /gene="pheT"
                     /locus_tag="ACG804_001471"
     CDS             9146..11566
                     /gene="pheT"
                     /locus_tag="ACG804_001471"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HFS4832407.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="ACG804_001472"
     CDS             complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="ACG804_001472"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HFS4832408.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            13000..13737
                     /locus_tag="ACG804_001473"
     CDS             13000..13737
                     /locus_tag="ACG804_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFS4832409.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13751..14566
                     /locus_tag="ACG804_001474"
     CDS             13751..14566
                     /locus_tag="ACG804_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFS4832410.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14579..15226
                     /locus_tag="ACG804_001475"
     CDS             14579..15226
                     /locus_tag="ACG804_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFS4832411.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15242..15898
                     /locus_tag="ACG804_001476"
     CDS             15242..15898
                     /locus_tag="ACG804_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFS4832412.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16060..16881
                     /gene="racE"
                     /locus_tag="ACG804_001477"
     CDS             16060..16881
                     /gene="racE"
                     /locus_tag="ACG804_001477"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HFS4832413.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16884..18239
                     /gene="rph"
                     /locus_tag="ACG804_001478"
     CDS             16884..18239
                     /gene="rph"
                     /locus_tag="ACG804_001478"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0009022 - tRNA nucleotidyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HFS4832414.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18240..18758
                     /locus_tag="ACG804_001479"
     CDS             18240..18758
                     /locus_tag="ACG804_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFS4832415.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18865..19365
                     /gene="cbpB"
                     /locus_tag="ACG804_001480"
     CDS             18865..19365
                     /gene="cbpB"
                     /locus_tag="ACG804_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HFS4832416.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19645..20565)
                     /locus_tag="ACG804_001481"
     CDS             complement(19645..20565)
                     /locus_tag="ACG804_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HFS4832417.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20691..21743
                     /locus_tag="ACG804_001482"
     CDS             20691..21743
                     /locus_tag="ACG804_001482"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HFS4832418.1"
                     /translation="MIKCGENNEGGKYMQIDWNNLGFSYIKTPWRFIAKWKDGQWEEG
                     ELTEDNYLTIHEGSPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLM
                     PMVPEKMFVDAVKQVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVF
                     CTPVGAYFKGGLKPTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCV
                     YLDPATHTKIEEVGAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIE
                     GDIFIDDLDQFAEAGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGI
                     QFGDIEAPEGWIEVVE"
     gene            complement(21853..22608)
                     /gene="fabI"
                     /locus_tag="ACG804_001483"
     CDS             complement(21853..22608)
                     /gene="fabI"
                     /locus_tag="ACG804_001483"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HFS4832419.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            22828..23268
                     /gene="fabZ"
                     /locus_tag="ACG804_001484"
     CDS             22828..23268
                     /gene="fabZ"
                     /locus_tag="ACG804_001484"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFS4832420.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(23383..24144)
                     /locus_tag="ACG804_001485"
     CDS             complement(23383..24144)
                     /locus_tag="ACG804_001485"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFS4832421.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            24333..25427
                     /locus_tag="ACG804_001486"
     CDS             24333..25427
                     /locus_tag="ACG804_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HFS4832422.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
BASE COUNT         8441 a         4420 c         5378 g         7221 t
ORIGIN      
        1 tttttgcgta tacttaaaaa agtagaaata tcagaacctt aaaaggatat aatttgaaga
       61 atatagaaca aatgttcagt attttttgat ataataaagg agcaccgtat catgtgttga
      121 aggaggaaaa gcatgtcttt acaatttatt cttggaaacg ggaaaaaaga tcaccgtcaa
      181 gtcttgatcg acgaagcatc cgcttggctc gaccaggatg caagtaacca agtatttttc
      241 cttgttccca actacagcaa attcgaacag gaacaagaaa ttttagcgga gatgcgaaga
      301 agaagcggaa aaaaaacttt cagcacaaca aacgttcaag tatttagttt ttatcgtctg
      361 gcttggtatt tgctgcaaca gacaactctt cttacaggaa atgaattatc agaatcagga
      421 tctgcaatga tcttgcgaca gattttagaa aaaaatgagg aagaattaac aatctttcgc
      481 ggagaaatca ataaaagagg gtttattcgt caattacaag aactctacag tgaattgcgt
      541 acaggaaata ttcaaccaga agacctgatg cttttatttg gtgattcacc taatgcagaa
      601 gaccagcaac ttaaaatgaa agacttgaag ctgatttttt cagcttatga cagcgaattg
      661 actcaacgtg cactaacaaa tgaagatgca ctatctatac tagcaaatta tatgcagaca
      721 caagatttca acaacgtcaa atttattgtc agtggttttt ctcgaatcaa tggtcaagag
      781 tatcaattac tgcaggcaat gatggaaaag gggcaattgg ttgtcgattt attgctggat
      841 cgtccttata cagcggatct tccagaagta cttacgctct ttcatgagac tggaaagctt
      901 tatttccgtc tttttcaaag tgcaagagaa cggaaagtcc ctatattagt ggaccgattt
      961 gcaccagagc agactcgtcc gacagagctt caactgctgc aaacaatgtg ggaagagaca
     1021 tctagccaaa agaaagcggc agtacacaaa atagggggac aagagcatct ccatttgtgg
     1081 gaagctgaaa atccaactga agaagtccga caattagctg ttgaaatcag acgactagtc
     1141 agtgaagaaa actaccgtta tcgtgatatc caagtgctga caaaaaatat gtctttatat
     1201 ggaaatatcc ttcggccgat ctttcaagaa atggcaattc ctttttatat cgatgaagaa
     1261 caaatgatgg aaaatcatcc gctgatcgaa tggatcaaca gtctgttcgc tcttgaccgc
     1321 tattcttatc ggctaagtga tattatgcgt tttttcaaaa ctgaattatt tctgtcgacg
     1381 gaagcagaaa ccgaacttga tgaatggaaa caagagcgag atgaattcag gaaaaaactg
     1441 gacatcactg aaaatgtagc acttgcttac aattatcaag gaacttattg gactcgtgaa
     1501 aaagactggc agtttgtggc gtatgatttt gaagcagaac agattgaaga cgtacagtat
     1561 ttggaagaac agtcaaatac gattagacga ttatttcaga aagctgtacc agtatttttg
     1621 aaaaaaataa agaaaagcaa aacaggacaa gaggccgcaa atgtttttta tcaatttttg
     1681 atccaaagtg gcgtacagca acaattattg ttttggcgta atcaggaagt agacagagga
     1741 aacttagaag cggcaagaaa ccatgagcag acatggggag cgctgattga tctgttggat
     1801 gaatatgtag taatttatgg tgaatcggct tttgactggt cactgttcca agaaatcatt
     1861 acaagtggtc tagaaaatct aagttatggt aaaatcccta ccgcaatcga ccaagtgcga
     1921 atcaatcgtt tggaattagt tcgaccaaat caagctgccg tcacttttgc attagggttg
     1981 aatgatcaag tgtttccaga ccgaaaagag acaaaaggat tgttgtccag tgaagaacga
     2041 gaagtattaa atcaggcctt gccagatgga cagtttttat tcgacccatc aaaggaaagt
     2101 atctcttttg agcctttcca agcctatctt gtttttcttt ccggaacaga tcgattatat
     2161 cttagttatg cacaaagcta tgacacagat ggttcgctga agatgtctcc ttatttgcgt
     2221 agaatcacag aatatttatc tgttcccgtc gagagaaaag agcatttgac gatcgaaagc
     2281 gaccctaatt gttatgtagg gacttacaga agcggaatca atacagtcaa taggatttat
     2341 cgattagctt tagatgaaaa aaaacctgta ccaaagcact ggcaaaagct caaagaatta
     2401 gtactgaatt cgtcatggcg aaattttgct ttacagattt ttgaaagtca ggaacattta
     2461 aatgttcctg tttcgatgcc agaaaaaatg gcggaagagc tttatggaaa agagatttat
     2521 acttcaattt cacgtatgga gaatttttat aattgtgaat acaaatactt catgcaattt
     2581 ggtttgaaat tgaaagaacg aactgtttat ggtctaactc cagcagcaac tggtgatttt
     2641 tatcatgaat cattggatcg tttcttcaag ctactgtttt caaaccaatt atccttagtg
     2701 aatatgtccg atgcgcagcg tagagacttt actgaaaaag tgctgcagga agtattcgga
     2761 gaacttcggt ttgagatatt ggatagttct gcaagaatga actatatccg ctaccagtta
     2821 ggacagacga ttcaaaaagt gacatgggct ttgcaaaaac agagcaaaaa tacaggcatg
     2881 catcctcttc agacagagat tctatttggt cagattgctg gagcaaaagg tatcacaggt
     2941 ctggaattac cgttgagtaa tggtggaaaa ctccatgttc gagggaaaat cgatcgaatc
     3001 gatgtagctt ctgaacaaga agatacttgg ctaagcgtcg ttgattacaa atctagcgga
     3061 cgttcattcg atgtcacaga agcttattat ggcatggcta tgcaattatt gacgtatctg
     3121 gacgtagcat tgatggatgc ggtacgtttg actggaaagg cggctgttaa accagcagga
     3181 tcatattatt tacatgttca taatcctgta ttgacggaga cagatgatgt agagaagaat
     3241 acattgaaaa aatttagtta tgatggcgtt tttgtcgatg atcccgctct tttagaagta
     3301 ctagatcatt cactggaagc aaaagaacaa tcactgatct atccagtgaa aaaaaatgcg
     3361 aaagatgaat accaaaaagg tagtttcagt aaagacaaat ttttcacgga agaagaactg
     3421 caactattca tggcgcataa tcgggaaaat atgcggttag ctggagatgc gattacttcc
     3481 ggagaaatca aactaaatcc agcttataaa gataaacagc ggattgcctg cgaattttgt
     3541 ccattcagaa gcatctgtac gtttgatgtg atgctgaaag aaaataatta ccaccgtctg
     3601 gagaaaatag ataaggaaga agcactgcgt agaatattga aaaggagtga agaagagtga
     3661 atcaaattcc tttaaaaccg caaaatgaac gattcacaga tgatcagtgg caagcgattt
     3721 ttgatcaagg agataatcta ttagtctctg cgtctgccgg atcaggtaaa actacagtgc
     3781 ttgttcgaag agtgattgaa aaactaaaaa tgggttttga tatcgatgaa ttattgattg
     3841 tgacatttac tgaagctgcc gcaagagaaa tgaaagaaag aattcaagag gcattacaag
     3901 aatccgtcaa tagcgaaagt gaccctgtac gtagacagca ttttactaag cagttagttt
     3961 tattgcccac agcgaatatc tcaaccttac atgctttttg cctgacagtt attcgacgtt
     4021 attattactt aattgatatt gatccagtct ttcgcatgtt aacagatgaa acagaaacga
     4081 tcttgatgaa ggaggatgtg tgggacgagc tgagagaagc actttatgca gaaaatgatg
     4141 aacgattttt ccaattaaca atgaattttt ctaatgatcg ttcagatgac ggcttgacga
     4201 atctggtgtt ttctctttat gagtttgccc gtgccaaccc tgacccccaa aaatggctag
     4261 aacagttaag cgataattat cgtttgcctg aggggctagc gaaatctcga ttatatcaaa
     4321 aacaaatccg tcctttagtt ttggcagata tataccaatg tgtacagtta tatgaacaga
     4381 tgactcagtt agcacaaggt gaaggattag aaaaaatgca tgagcaagta gctggagaac
     4441 aacagcagat caagaatatc tatgaagcgt tctcgcaaga tcggttagaa gaagcttatg
     4501 ctggtttgga acaactaact ttttcaactt ttaagagcag tcggaaagca gaattgaaag
     4561 aaatttccaa tgaagtcaag ggcatgaggg ataaagcaaa aaaactgatt cagcagataa
     4621 gtaaaagtta ttttcctgtt tccccaagcc aaatggaaga attaacggac aaagcactac
     4681 cgttagtcga agaaatgaca aaagtcacgc aaagcttcat ggacggtttc agtatgcgta
     4741 aacgggaaaa aggtgtgctg gatttcaatg atctggaaca tttagcgttg cagattctca
     4801 cagaaaaaac gaaagatgta tggctgccaa gtgaagcttc aaaacattat cgaaaaaaat
     4861 tcaaagaagt aatggtagat gaatatcaag acgtgaacca attacaagaa gccattttat
     4921 actggctaag agaacccgat gatacaaaag gaaatatgtt catggttggg gatgtcaaac
     4981 aatccatcta ttctttccgt ttagcagatc ctagtttatt tatcgggaaa tacgagaatt
     5041 tctcaaagaa agaaggcgga cgtcgaatcg ttttggctga gaacttccgc tctagaaaag
     5101 aagtcctttc ttttacgaat cttatttttg aacaactaat ggatccagca gtgggtcaaa
     5161 tcaattatga cgaagcagcc aaactgatcc aaggattttc agactttcca gagaatgaac
     5221 agtttgagcc ggaaatcatg atctatgaaa aagaacagga agaatcagag attgagattc
     5281 cgacggatga tatactggaa gacaaaacag aaggcgaact ttttatgaca ggactaaaaa
     5341 ttcgtcaatt aattgattcc tcctttatga tttatgataa aaaatcaaaa aaaagtcgtc
     5401 cgatagagta caaagacatt gttctcttga cacctacaaa gaagaacaac ttaacgattt
     5461 tagagatttt caaaacattg gatattccat tagagatgaa tgatgctcaa aactattttc
     5521 aagcgacaga aattcgcacg atgatctcgc tgctacaatt aatcgataat ccctatcaag
     5581 atattccgct tgcggctgta ttgcgctcac cgatcgtggg tctgattgaa ccagaattag
     5641 ccagcattcg attagctaac cgtgcacata cttactatga tgctgtgctt gcttatcaag
     5701 catcaaacga agatgaatta gcagctaagc tggaacattt tggcaagcaa ctagagcatt
     5761 ggcgagaact tgctcgccgt tcttcgatca ctgacttgtt atgggatatc tattatgaga
     5821 cgggatatct agagtatgtg gtcggtctgc cagcaggggc acagagacaa gccaatcttt
     5881 atgcattggt tgatcgtgcc aaagcttacg agcaaagttc tttcagagga ttataccagt
     5941 tcgtgcgttt cattgaaaaa atgcaagaaa aagataaaga cttagcagaa ccagtcattt
     6001 caatagaaga taatgctgtt cgcgttatga cgatccatgc aagtaaaggc ttggaattcc
     6061 cagttgtatt tttgttagat atgacaaagg agttcaactt acaagacttg cgcaatcggt
     6121 atgcttttga agaaaaactt ggagcaggaa ttcgctatat ggatcctgaa acacgagtgt
     6181 tatatgatac gttaccgttt caagccatca aattggcaaa gcaaaacaaa ttgttgtcgg
     6241 aagaaatgcg taaattgtat gtaggattga ctcgggcaga acaaaagctt ttcattgtcg
     6301 gttcctataa aaataaagag caaatgatcc aaacgtggtc tgaagcagct gatcatgagg
     6361 agttagtttt tgatcctgcg ctacgtttga agggcagaag cagcttgatg aattggattg
     6421 gttacggatt gatccgtcat cctgaaatgc agaaatactt agaggaagaa atttcgactt
     6481 ctcttcttca acattcaaat gcacagtttt ctatttcatg gatgaatcag caatcgatca
     6541 ttgaacaaag acagttgctt gctgaaaaag aactggttaa cttagatcag cagatgaaag
     6601 aagatgaaac tttattagca gattcgttac aaaaacgtct ggcatatgaa tatccttatc
     6661 aagcttcttc acaaaccaca agttatcaat ctgtatctga aatcaaacga ttattcgaag
     6721 atccagatga tacacaagaa tcacgtttga ctctggaaag cagtcagaac aaagcagcat
     6781 cccgtcaatt tcgttatacg caagaacaac tagcagaacc aaaatttttg caaaaagatc
     6841 ggcaagtgtc agcagctgct gttggaactg ctacgcatgc tttgttacaa ttactgccat
     6901 tagagatgcc aactacagag agtatccatc aaaaattaca ggaattggta aggaaacggt
     6961 tagtagacga aaaagtcgcg aaaaaagtag atgtttcttc tattatatgg ttctttcaaa
     7021 cagaacttgg tcaacagctg attgccaaca aagaaaacgt aaaacgagaa caaccttttt
     7081 ccatgctgct tcctgctgac gaagtatttc aagactatcc aaatcaagaa gatgaactat
     7141 taatccacgg aatcgtcgat ggatacctag aagaaaaaga tcatctcaat atctatgatt
     7201 ttaaaacaga ttttatttta catccggatg atccagcaga aatagatgca atcgtccaaa
     7261 aatatcaagg acagctaaga ctttaccaac aagcaatgtc agaagctttg aataagccag
     7321 tagaaaatgt tttcctaatt ttgcttcgag tgaaacaaat tataaacatt aacaaataat
     7381 tataattgag caaacttgac ttatgttttg taaggattat gctatactct gggaagaggt
     7441 gagtatgatg gagctaacac agacagaatt cgttttatgc cctaaatttg aaaaaacatt
     7501 ctctatttta ggaaaaaaat ggaacggatt gattatcgat gtactactcg aaaacggtcc
     7561 gcaacgcttt gttgagcttg cggcaaaaat cccgatggtc agtgatcgag tattagtcga
     7621 acgcttgaag gaattagaaa aagaaggaat agtcactcga aactttgcct gtagcgaaaa
     7681 gagccgttca gaatatctct tgactgaaaa aggagcagac ttgcaaaaag cgatgcgtca
     7741 aatacaagtt tggagcgaaa aatggatcac agaggaagaa tgcggttgat tttgtaaaaa
     7801 aaatcttgta aactatagtc catacgaata agtaaagaac gatgacgaaa aagagtagtt
     7861 tggctaaacc agttcaggga gatctgtcgc agactgaaag cagatcctgt gtttgaaaaa
     7921 tgaagttcac tttccgagtt cgtctgataa aatcagaccg gcaattgtcg ttaacgaagt
     7981 aagagtgcgg tgtaagtcat ttatccgcaa attaggatgg taacgcgaag acctcgttcc
     8041 ttaacaggaa tgaggtcttt ttgttttgta tttggaattt aaaggaggaa caagcacatg
     8101 tctctacaag cacaattaga gagcttgaaa gaagcaacgc tcgtcaaaat cacagcggca
     8161 caagatttaa atgaattaaa tcaaatacgt gttgaaacgt taggaaaaaa aggaccgatc
     8221 acagaagtat tacgtgggat gaaagatcta agtccagaag agcgaccaaa agtcggaagt
     8281 ttcgcaaatg agatccgaga tcttttgaca gaagagatcg agcgaaaaaa acaagtatta
     8341 gaagaagaag cgttaaatgc agctttggca aaagaaacaa tagacgtgac actacctggt
     8401 agaaaagtaa aacatggtac acgtcatatc gtgacacaaa tcatggaaga aattgaagat
     8461 atttttgtgg gtatgggcta tcagatcgta gaaggatatg aagtagaatc tgatcattac
     8521 aatttcgaac ggatgaatct gccaaaagat catccagcaa gggacatgca agatactttc
     8581 tatatttcag acgagatatt gattcggaca catacttcac cagtccaagc acggacaatg
     8641 gaaaaacatg atttctctaa gggtgctcta cgaatgatct cgccagggaa agtcttccgc
     8701 agagatacag atgatgcgac ccacagtcat cagttccatc aaattgaagg gctagttgtt
     8761 gataaaaaca tcacaatggg cgaccttaaa ggaacattag aagtcgtaat gaaaaaaatg
     8821 tttggggaag atcgtgaaat tcgtttgcgt ccaagttatt tcccatttac ggaaccatca
     8881 gtagaagtag atgtcagctg tttcaaatgt ggtggtgccg gttgtaacgt atgtaaatac
     8941 actggatgga tcgaaatttt aggagctggc atggtacacc cgaatgtgtt gaagatgtca
     9001 ggaatcgatc cagaagaata ttcaggcttt gctttcggcc ttggaccaga ccgcgtagct
     9061 atgttgcggt atggagtgaa tgatatccgt aatttctatc aaaatgactt acgtttctta
     9121 agtcagttca agggggagta agaaaatgtt agtttcatat aaatggctca atcgttatgt
     9181 agatttatcg aatgtaacac caaaagaatt agcggataag atgtctgtga caggaatcga
     9241 agtagaggga gtaacggttc cagaagaagg cttgaaaaaa atcgttgtcg gtgaagtcaa
     9301 ggaatgcgta ccacatccag attctgatca cctttctatt tgtcaagtcg atattggcga
     9361 agacgaactg tctcaaatcg tttgtggagc gcctaatgtg aaggttggaa tcaaagtgat
     9421 tgttgcactt cctaactcac gtatcgctgg taatgtaaaa atcaaaaaag gaaaaatgcg
     9481 tggccaagta tcaaatggca tgatttgctc attacaagaa attggctatt cagatagtgt
     9541 tataccgaaa gaatacgctg aaggtatcta ttatatgcca caagaagctg taaatggcga
     9601 tccagttttt ccttatttgg atatggatga ttcgattatt gaattatcta tcacaccgaa
     9661 tcgtgcggat gcattgtcaa tgcgtggcgt agcttatgaa gttggggcaa tttatcgtca
     9721 gactcctaca ttcgatgacg aaaagctggt agaatcctca cgtcctgcta gcgataaaat
     9781 tcaagtggaa gttgaagata aagaagcagt tcctgcttat caaatcagaa tcattgaagg
     9841 agtaagaatc cagccaagtc ctcaatggct gcaaaatctt ttgatgaacg aaggcattcg
     9901 tccaatcaac aatgtagtag atgtgacgaa ctatattttg cttttattcg gacaaccact
     9961 acatgcattt gactacgaca aattgaaatc aaaagagatc tttgtccgcc gtgcaaaaga
    10021 aaatgaaaca ttagtaacac tagatggaga atctcgggaa ttgacaactg acaatctcgt
    10081 cattactaac ggcaaagaac cagttgcttt agctggtgtc atgggagggt tagactcaga
    10141 gatcacgaat gaaacaacaa cagttgcact agaatctgct ttatttgatc caatttcgat
    10201 tcgtcgtaca gcaaaacaat ttaatttgcg tagtgaatcc tctgcacgtt ttgaaaaagg
    10261 aatcaaccat gcgactgttg gagaagccag tgaggttgct gcagcaatga tcgtttctct
    10321 tgcgggtggg gaagttctac aaggcgcggt caaaggctca gagatcaaag cagaagacgt
    10381 atcagtgaag atttcacttg aacgcatcaa tcaatattta ggaacatctc ttgtcgttaa
    10441 agaagtaaat gagatttttg aagcacttgg atttagctat gaagaaaagg agtatgttta
    10501 ttccgtagta gtaccaccaa gacgctggga tatccaaatc gaagcagata ttatcgaaga
    10561 agttgctcgt atttatggat acgaccagtt gccatctaca cttccaagtg gagaaacggt
    10621 tgctggaagc ttgtcaaaag aacaagaaac tactcgtaaa attcgtacaa tctttgaagg
    10681 aagcggattg agcgaagcaa tcagttatgc attgacaaca gaagaaaaat caagacagtt
    10741 tgttataaat gaaagtaata ttacacgttt ggactggcca atgagcgaag aacgttctgt
    10801 attacgaatg aatttgatca gcggactatt agatgatatc agttataaca ctgcccgaaa
    10861 aaatacagag attgctttat atgaaattgg tcgggtgttc ttccaagaaa atgatccacg
    10921 tacacatctg ccgcaagaag taaaacatgc agcaatcgct atttctggta tttgggaaga
    10981 aaaagattgg cagacgaaag ctcaaaatgt agactttttc accatcaagg gtcttttaga
    11041 aaacttattt gaacaactag gcatcactga agatgtccat tatcaaacag tgacagaaat
    11101 gaaggaaatg catcctggaa gaactgctgc gatttacctt ggcgaaaaat ttattggttt
    11161 tgtcggtcaa gtgcatccaa cgattacaaa aagttatgat attccagaaa catatgttgc
    11221 tgagtttgat ttatctgcta tagtggaagc tgctcaaaaa gggatcgttt tcgaagcagt
    11281 gacaaaattc ccagcagtca gccgggacat cgctttgctt gtaaaagaaa ctgtgacaaa
    11341 tcaggaatta acagaagtta tccgttctgc tgccggaaga tttttaacag atatccaatt
    11401 atttgatgtc tatcaaggag aaaacattga aaaaggacat aaatccatgg cgtatagcct
    11461 gacattcgtc aacccagaag caacattgac agatgaagaa atcaataaag caatggaaaa
    11521 agtcgaaaaa gcgttggtag aaaacctaga ggcaagtatt cgctaagaag gaaaatatag
    11581 taagtaacga tcaagtagct tttgaagacc atacatttga aaaaaagatg tgacacaact
    11641 tcgtcacatc tctttttttg attttaaaaa aggaatagca cagagacgag ataaaaaaac
    11701 aggcctttac agcctgcttt tttagagtaa atgaattaat ggaagtaatt gattcccatt
    11761 gctgatttta cttcagaaag tgtttgtgca gctactttag cagcttcttc actaccttta
    11821 cgtaagattt ccataacagc tgaaggatct ttttccaatt cttctcggcg cgcacggatc
    11881 ggtgcaaatt cagcttccaa tacatcaatg aggtatcgtt tgatctttac atcaccaagt
    11941 ccgccgcggc ggtaatgagc tttcatttct tcaattgctt ctttatctgt tccgaataca
    12001 tccaagtagg tgaagaccat attcccttct acttgtccag gatcttgtac atggatgtgg
    12061 tttggatcag tatacatact catgactttt ttctgtaaga catcggcagg atcggagata
    12121 taaataccgt ttcctaacga tttactcatt ttgccatttc catcgattcc aggtaatcta
    12181 cccattcctt ttggtgggaa tacgcctttt ggttccacca agacttcacc atatgtatga
    12241 ttgaagcttt gtacgatttc ctgtgtctgc tctagcattg gtttttgatc ctcaccaaca
    12301 ggtacaagat tcgctttgaa tgcagtgata tctgctgctt gagaaacagg atagataaag
    12361 aatcctgtag gcacgctttc accgaatttt ttttgttcga tttctgtttt gacagtcgga
    12421 ttgcgccgaa cgcgtcctac gctgactaag ttcaaataat acatggttaa ttcagctaat
    12481 tccggaattt gtgattggat aaataaagta gattttgcag gatctaatcc cacggctaaa
    12541 tagtctaaag caacttgcaa gacatttgat gaaaccttct caggattttt agcattatct
    12601 gtcagtgctt gcatgtcagc aatcatgaca aacagttggt tgtcttcatc tgcctgcata
    12661 gccactcggg tttttagaga accgacgtaa tgccctaaat gcagcttccc agttggtcga
    12721 tctcccgtta aaataatatt tttcaaaaaa gacacctctt tacgatttgt aagtctgagc
    12781 acttaatatc ttaccgtttt tcctgaaaag aaacaacagt tcctaaggaa aaaacaagga
    12841 aagaggataa aataactaat agattagaaa tggaagaaat atttatggga gaataaacgt
    12901 tctaagaaac tttacaaatt actaaactat cagatataat gtattttatt atacatcttt
    12961 aaaagaaatc ttactaaata ataatgggag tgtaattcta tggcaatgat taaatttgat
    13021 cacgtggata aatattatgg caagttccac gcattaaaaa atatcaatct cgaattcgag
    13081 aaaggagaag ttgtcgttgt cattggtcct tctggttcag gaaagagcac gatgcttcgc
    13141 tgtatcaatg gattagagac gatctcttca ggtaagctgc tgattaatga tactgacttg
    13201 catgataaaa agacaaaact gacagaagtc cgaaaaaaca tcggcatggt tttccaacat
    13261 ttcaatttgt acccaaataa aactgttctg gaaaacatca aattagcacc aatcaaagtg
    13321 ttgaagcaag accaggcaac tgcagtcaaa aacgcggaga aatttttgaa aactgtcaat
    13381 atgttagata agaaagattc ttatccttcc atgttatccg ggggacaaca gcaacgggtg
    13441 gcaatcgcca gaggtttagc gatgaatcct gagatgctgc tgtttgatga acctacttct
    13501 gctttggatc cggaaatgat tggtgatgta ttagacgtta tgaaaaaatt ggctcatgac
    13561 ggtatgtcaa tgattgtcgt gacacatgaa atgggctttg ccaaagaagt ggcggatcgt
    13621 gttatcttca tggctgatgg agaagtattg gaagacagca gaaatgtgag agactttttc
    13681 gaaaatccaa atgaagtccg agcacagcaa tttatcagta aagttatcaa tcattgatag
    13741 gaggaaaaag atgcgcaggt taaaaaaaat acgcctgatt ttccttttag gcattgcttt
    13801 tcttgcacta gccggatgta aaggaaatgg gttggcaaat gaagatattt tagagcgaag
    13861 caaatctacc aatgaaatca tctggggtgt caagtatgat actcgattat ttggaatgat
    13921 ggatattgag agcagaactg tacaaggatt tgatgtagat attgcaaaag caatcactaa
    13981 aaagatcctt ggtgacaatg gaaaaacaga atttgttgaa gtcacttcta aaactcggat
    14041 tccattattg aaaaacggaa atatcgatgc aattattgca acgatgacga tcacagatga
    14101 acgaaaaaaa caggttgact tttcagatgt ctatttcgat gctggccaag ctttgttggt
    14161 aaagaaagga agccaaatca aaagtgtaga tgatttgaat gcttctacaa cggttctagc
    14221 agtcaaaggt tctacatcgg ctgcgaatat ccgacagcat gcaccagatg caaaaatttt
    14281 agaattagaa aactatgcag aagcatttac tgctttacaa tctggtcagg gagacgcgat
    14341 gactacggat aatgcgattt tgttagggat tgcagatgaa aatccagagt atgagttagt
    14401 tggtggaacg tttactaatg agccttacgg gattgcgatc aacaaagggc aagaaaactt
    14461 cttgaaagct gttaaccaag cgctagagga aatgcatgca gatggcacat acgataaaat
    14521 ctatcaaaaa tggtttccaa atgaaactga aggaaaagta gagtaagggg gagaggcaat
    14581 gagcgaattg atacaaactt atggaccaat ctttgtcgac gggttcaaga tcacattgtt
    14641 ttcgagtgtc ttagcacttg tgtttagttt gattatcgga acgttaatgg caatcttcca
    14701 attatcaaag aataaagtag tgagcgcctt agcaaaggca tatgtagaat tttttagaaa
    14761 cattccatta ttaatcatcg tgatgttttt ttatgttgtc gtaccgattt attggtttaa
    14821 tctagatgga ttccaagcag gtacgattgg attaacgatc tatacatctg cttttattgc
    14881 tgaaacagta cgttcaggga ttcaaaccgt accaaaaggt caaacagaag caggactatc
    14941 ttctggtttt acctattcag aaatcatgcg ttatattgtt ttaccgcaag cattcaaaat
    15001 cgttatcccg ccattaggca accaatttat caacctcgta aaaaactcat ctattttagc
    15061 aatcgtagct ggtttagatt tgatgtatca aggagacttg atcgctagtg aaacattcaa
    15121 taccttcgat acgtatatca tcgttgggtt attttactta gttatcacgc taccgttatc
    15181 ttacttaatg gtttatcttg agaaaaaatg ggcggttcgt tcatagaagg aggggaaata
    15241 catggatttt agcggcgctt tttcatggat gaatatccgt tttttattgg aaggattaaa
    15301 ggttactgtt gaagtttcat tgttttcgat catttttagt ttcttgatcg gtggtctgac
    15361 aggtgtgatt cgttttgcga atatcccttt cttttccaaa atccttggtg tagtgattga
    15421 tattatacgg aatcttccat tattattgat cattttcttc acttactttg ccttacctca
    15481 aatcggcatt cagatgaaca tcttctggtc cgctgtcgca gcattaacga tttttgagtc
    15541 agctatgttg tcggaaattt tccgagctgg actcaatgct gttccaaaag gacagatgga
    15601 agcaggatta tcaacgggac tgacttatgt agaatcgatg cgaacgatcg tgttaccgca
    15661 agcatttaaa tcaatgatcc cggcaattgt gagccaattg atttcactga tcaaagatac
    15721 ttcattagca gtaatcattt ctttacctga actttctcat caggcacgta ttatttatgg
    15781 acagaacacc aattatgtgc ttccgatgtt catcatcatg acacttatgt acttcgtggt
    15841 atgttacgcg ctttctctgc tttccggtta cttggaaaag agacggtaca gttattaata
    15901 gatgattctt ttagcggttg tggcaaacta aagtcacaac cgcttttcct ctttccattc
    15961 gaaaaaaaga gatttcgatt gttttaagca agtaagagca cttgaaaatt cacgctaaaa
    16021 agtacacaat agggaggata gaatttattg aaaaaaagga tgatacgatt gacagataat
    16081 cgccctatcg gatttattga ttcaggtgtc ggcggcttga ctgtagtaaa agaagccctg
    16141 aaacaattac cgaatgaaaa tattttattt gtaggagaca cagcacgctg cccatatggc
    16201 cctagacccg cggaacaggt aatccagtat acttgggaaa tgacggatta tctggtggag
    16261 caaggaatca agatgctggt gatcgcctgc aataccgcaa ctgcggtggc tttagaagaa
    16321 atcaaagctg ctctttctat tccagtcatc ggtgtgatcc ttcccggtac tagagcggca
    16381 gtaaaaaaaa cacaaaataa acaagttggc attatcggta cgattggtac ggtaaaaagt
    16441 caagcttatg aaaaagcact gaaagagaaa gtaccagaat tgactgtgac aagtcttgct
    16501 tgtcccaaat ttgtttcagt tgtcgaaagt aatgaatacc attcatcggt ggcgaaaaaa
    16561 attgtggcag aaacattagc tcctttaacc actaaaaaaa tcgatacatt gattttggga
    16621 tgcacccatt atccattatt acgccccatc attcaaaatg taatgggaga aaatgttcaa
    16681 ctgatcgatt ctggagcaga aacagtaggt gaagtatcta tgctgttaga ttatttcaat
    16741 ttgagcaatt caccgcaaaa tggtcggaca ttatgccagt tttatacaac tggctctgcc
    16801 aaacttttcg aggaaatagc tgaagactgg cttggaatcg gacacttaaa tgtagaacat
    16861 atcgaattgg gaggaaaata aggatgcgtc atgacgggag aaaagcccaa gagcttcgca
    16921 aactggagct tcaaacaaat gttttcaaat atccagaagg atcggtagtg atccgttttg
    16981 gtgatacaac agttatttgt tctgcaacaa tagaaaattc tgttccccct tttttgagag
    17041 aaacaggaac aggatgggtg acagcagaat atagtatgct gcctcgagca acgagtacga
    17101 gaaatcgtag agaaagcagc aaagggaaac tttctggtag aacaatggaa atccagcgtc
    17161 ttattggtcg ttccttgcgt gcagtagtag acttggaaaa attaggagaa cgtagtatca
    17221 tcgtagactg cgatgtgatc caagcggatg gcggtactag aacagcaagt atcactgggg
    17281 catttgtggc attgaaatta gccattgaaa aacttttaag agaaaaagaa ttgtcagaag
    17341 atccaataaa agaacatctt gctgcagtta gcgtaggaat cttaccagat gggacttgcg
    17401 tcacagattt ggattaccaa gaagattccg cagcacttgt agacatgaat cttgtaatga
    17461 cagaatctgg aaaattcgtg gagattcaag gaactggaga agaagcaacg tttgatggtg
    17521 aacagttgaa tgaaatgctc ttttttggaa aaaacgcgat tgaagatttg atcaaagagc
    17581 aaaaacatgc tttgctaaca gagtttgctc aaaatgatga gcggatagaa gaaacaaaaa
    17641 caatcatcat tgcgacaaga aatccaggaa aagcagaaga gtttcgaaat atgttcaaag
    17701 aagcgggata tcatgtaaaa acattacttg actatcctga attgccagat gtggaagaaa
    17761 ctggcagcac atttgaagaa aatgcccgat taaaagcaga aacgattgca caattgcttg
    17821 atcagccagt cttagcagat gattcaggtt tgaaagtgga tgctttaggc ggtatgccag
    17881 gaatctattc tgcacgtttt gcaggggaac aaaaaagtga tgcggggaat aacgccaaat
    17941 tattatatga attgacagat gtgccggatg aaaaaagaac agcacaattc cattgtacgt
    18001 tagtattcgc ggcacccaaa aaagacagcc ttgtagtaga agcggaatgg cccggtcgag
    18061 tagcccgtat accatctggc gaaaatggct ttgggtatga tcctttattt atcccagaag
    18121 gtaagaaaca aacagcagca gaattatcga gcgaagaaaa aaacaagatc agtcatcggg
    18181 ctcaagcaat gaaaaaattg agtgccgagt ggaaacaatg gctggaagga gagagataga
    18241 tgcggtattt agtagtaagt gataatcatg gagacagaga tatcctcgtt gacttagtag
    18301 atcgttatcg ttctgaagtg gatatctttt tccattgtgg tgattcggaa ttagaagctt
    18361 ctgacccatt atgggataca ttccaagtgg ttcaaggtaa ttgtgattat ggaccaggat
    18421 tcgaacagaa aaaagtgatc caaactggtc aggatacagt attcatgact cacggtcatt
    18481 tatcgaatgt ccgatttggt ttgacacagt tagcaatcga agctcgagct gcaactgccg
    18541 atatggtgtt ttttggtcat acccatcaaa taggctgtga gatggatcag aaaatcctgt
    18601 ttttgaatcc tggtagcatt tctcagccta gaggcccgat ccaaatccca tcatatgctc
    18661 ttatcgaaag tttagatgac caaatttctg ttcaatacta taaccgtgcc catcaggcag
    18721 ttgaagagtt ggccttttct ttttcgagag agcgctgaat aaaaaaactc taatttttaa
    18781 taaaaataag ctttatttta tgaattttgc atccggtttc ggtaaaatag tagtgttgaa
    18841 tgaaatagaa atggaggcca tcagatgatt ggacctatag taagagaaat gctgctggaa
    18901 aatcaggaaa cgtttttgat tcctgcagaa aatgtggcaa atgttatgta tcatcatcca
    18961 ttgtcccatg gtttacttgt gttatcgaag gtcggttatt ccaaaattcc tgtattagga
    19021 aaagatgatc actttgtagg actagtaagt ttatcagatg tggtcaataa aatgattgac
    19081 ttgcaaacaa tcagcatgga cccgttagaa ggactaacgg ttgctgatgt gacagaaaca
    19141 gatgttccga caattgatga aaattgggaa ctagaagaag tactccattt gttagtcgat
    19201 tcgccttttt taccggttgt cacagaagat cggattttca aaggaatcat tacaagaaaa
    19261 gagctgctta aagccgtaaa cttcatggtg catgaattag aacgtcgtaa tatattgtct
    19321 ccgaaaatcg aagaattaaa agaacaaatc gatatcgtga gctaaagaac gagaaactaa
    19381 aagataatca aaaaataagt agaaaaaaca gcgtaccagt tttgacttta tcttgaaaaa
    19441 gaggctggga caaaagcgtt taactccaag aaataagaag gaattcacga aaattgcttt
    19501 tcaaattttt gtgaatttca gcttatttcc gaaggagttg cttctgcttc cgccgtttat
    19561 acgtgtttag agcgtgggac aaaagtgttc tttacttttg tcccacgctc tttttagtga
    19621 gattcgttgc atcgtttgtc caaattattt tccgacagca attggactgt tcggaatcgt
    19681 gaaaccagaa gctgtcaatt ctttgacata ggagctcaag aactcttctt ttaaggcata
    19741 ttgttttccg ttcaatgcgt agcagaccgt acgaatcgca aaattgctgt ttccaagatc
    19801 cactaatcca aagatagaag gttcagtttg gagctcttct tggtattttt cagctaatgt
    19861 acgatttact cgatcaatga tctcatagat tttgtcatat ccttcttcag gaacaatccg
    19921 aatatctaaa agtacttgca tatttgcacg agagagattg ctgatcgtgg tgatgtttcg
    19981 attcgggatg aaatggacag taccatccgt tgctttcagc tgaagggtac ggataccaac
    20041 agatacgacg gttccttcaa tcgttaagtt tgctagcttg atgtagtccc caacatccat
    20101 ctgttgttcc atgataataa aaaatccggt aataacatca ctcatgaacc cttgggcacc
    20161 aagaccgatt gccacacctg caattccggc accagccaaa agtgatccga tcggcacacc
    20221 gatagcagat aaaattgcat agataaaaaa gaaaccaagg gtataatgaa aaatagtatt
    20281 taaaagacta tgtaaagtct ttaagcggct ctcgtttaga atggcttttt tagaatactg
    20341 attaaaagac ttatcaatca gatattttcc cacacggtga agaatccaaa aaaggacgat
    20401 caaaaaaatc agatataaac ttttttggat aaaggcagcc aaaatggcgt cccaatcaat
    20461 cccgtcccaa aaccgctgaa acgcatttac tttgctgaca gcttgatctg tcaatgtctc
    20521 gccagaagag tctgtcgtac cggcagttgc taataatgaa aacataaaat cctcttttct
    20581 aaaatttgat tctttctgta ttgtaccaag aagttttcaa aaaaggaaat agcaaaaata
    20641 actataatga aggaaaaaag ctgaaaataa aatgacaaat aatatggata atgataaaat
    20701 gtggagaaaa taacgaaggt ggtaagtata tgcaaatcga ttggaacaat ctaggttttt
    20761 cttatatcaa aactccttgg cgttttattg ccaaatggaa agacggacaa tgggaagaag
    20821 gagaattgac agaagataat tacctgacga ttcatgaagg ctctccagcg cttcattatg
    20881 gtcagcaatg ttttgaaggt ctaaaagctt atcgtcgaaa agacggcaag gtcaatctct
    20941 ttcgacctga acaaaatagt cgacggatga atcaaagtgc tagacgattg ctgatgccaa
    21001 tggtccctga aaagatgttc gttgatgctg tcaagcaagt ggtaaaagca aatgaagatt
    21061 ttgtgccgcc ctatggaaca ggcgctacat tatacttgcg ccctttactg attggggtcg
    21121 gtgaaaacat tggtgtccat ccagctccag aatatttatt tgtcgtcttc tgtacgccag
    21181 taggagcgta tttcaaaggt ggactaaaac caacgaattt tattgtatct gattacgatc
    21241 gtgctgctcc taaggggact ggtgcagcaa aagtcggcgg aaattacgca gcgagtttac
    21301 ttccaggaac agaagcaaaa gaactggatt actcagattg tgtttatctt gatccagcca
    21361 cacatacgaa aatcgaagaa gtaggtgcag caaatttctt tggaattaca aaagacggaa
    21421 aattcatcac tccgcaatcg ccctctatct taccaagtat cacgaaatat tccttgttgc
    21481 agttagctga agaacgacta ggactgcaag caattgaagg agatattttc attgatgatc
    21541 tagatcaatt tgcagaagct ggtgcatgtg gtacagcggc tgttatttct ccaatcggtg
    21601 ggatttatca caataacaat cttcatgtat tttatagtga aacggaagta ggaccagtaa
    21661 caaaacggtt gtatgatgaa ttgacaggta ttcaatttgg agacatagaa gcaccagaag
    21721 gctggattga agtcgtggaa taatttcaaa gtaatgagtt gaaaaaaacg taaaaagaaa
    21781 aaatcaggaa gagactttaa aaagtttttt cctgattttt atatgtttta ctttaaagaa
    21841 tgcaacaaaa gtttatgaaa gatggacacc tttgtcaacg tagataatat caccgatgat
    21901 tccgctggaa agtgggctga ttaagaaagc acaagcatta ccgacttctt cgatcgtcac
    21961 accttgctga tcaggcgtac gagattcaga taactggatc agtttttgat agtctttaac
    22021 acctgtgaca gctaatgttt tgattgcccc agctgagatt ccattgaccc gaattccttt
    22081 aggcgagaac tcagctgcca aataacggat agcagcttca agagaagctt tcgcaatacc
    22141 catcatgtta taattcggga ttgcgcgttc tgaacctaga taagtcatgc taacgatccc
    22201 gctgtttggt gcaagaaacg gttgtgcgta ttttgataca gcaattaaag agtagctgct
    22261 gatatcttga gctaattgat agccgtctct ggaaatatca gacacatttc cggacaattc
    22321 ttctttgttg gcgtaagcaa ctgcatggac aaggccgtgg atctccccag catattcacc
    22381 gatggcattc attgcttttt cgatgctttc gtcgctagaa acatcacatt ctacagtgaa
    22441 tgcttcttcg ccgaccaatt tgactaatga ttttttcatt cgttcatttt ggtaagtata
    22501 gataatttct gccccttgtt tcaacattgc ttcagcacaa ccccaagcaa tgcttttttt
    22561 gttagcgacg cccataatga cgattttttt tccttctaga aatgacataa tgactctcct
    22621 ttgtttctga taaaaatttg atagtcgtaa aaaaatagag aataatagct aaaataactt
    22681 cttgatttct taattattag tcaaaatgtt ttgattgtca aactattttt tcttaaatta
    22741 aaaaaagatt gctaaatatt taggaatatg atactttgat agtcaaagta atgaaaatgg
    22801 caattgcctg aaagaaggag tttaattatg tcttacgtat tatctgctac tgaagtaatg
    22861 gaattgattc ctaatcgtta tcctatttgt tatattgatt atgtagatac tttagaacca
    22921 ggaaaaaaga tcgttgcgac aaaaaatgta acaatcaatg aagatttttt ccaaggtcac
    22981 tttcctgaca atccagtgat gccgggtgcg ttgattctag aaacactggc acaagcaggt
    23041 tcgatactta tcctaaaatc agaagagttt ctaggaaaaa gagcttatat cggtgggatc
    23101 aataaggcca aattccgtca aaaagttgtt ccaggagatg tgctgaaatg tcattttgaa
    23161 atcaccaaaa tgaagggatc agtcggtaca gcgttatctg cagcatatgt agatgataaa
    23221 aaagtctgtg agtgcgagtt cacgttcatc gtcaaccaaa atgcttgact ataaaacctg
    23281 atatagcaaa acaaaaggaa gcttacttgc tttttatgta aaaagaagac gcctgaatcc
    23341 tagcatacgt tgtcatctat gcaggattca gacgttattt ttttattttt gttttgcttc
    23401 ttgcagtata ttgattttat cgatttttac ttcttctttt ggtttgtctg aactatctgt
    23461 ttcgatattt gcaatagcat ccacgacatc cattccttca atcacttggc cgaagacagt
    23521 ataatggcca tctagtgaag gataaccgcc gtttttataa gcgtcgatga ttgcttgagg
    23581 atagtcgtct tttaaaagac catcatgcat atcatctgta ttttgaacga taaagaactg
    23641 gctgccgtta ctgttaggat cttgtgagcg agccatagat aacgcacctc ttatattata
    23701 aaggtggttg ttgatctctg tttcaaatcc ttctccccaa atgctttccc ctccagtgcc
    23761 atcgccttta ggatcgccac cttggatcat gaaatctttg atgacgcgat ggaaagtcag
    23821 tccgttgtag taaccgtctt ttgcatgtgt cataaagttt tcaaccgctt ttggtgcgtg
    23881 ttcgggaaat aatttgattt tgattgtgcc tttattcgtc accatttcga ccagatcttc
    23941 attttcggcg acatctttcg tcaattgtgg taattccaat gcgttcaaat cgacgctact
    24001 ggcagtcgtg ctttccgcag tagatgtact ttttgaactt tctgtagacg aactagaaga
    24061 agtcgtgttg tttgcagaac aaccagcagc aaacagcaat gctgctgcta aactaatact
    24121 taaaataact ttatttttct tcataactgt tcctttccaa tttactattt tgttatcttt
    24181 aatgataaca aaatagaggg aaaataccta cttaaattat tggaatttat catttatttt
    24241 aaaagaaaaa gaaaaggtgt agaccattta ctttgtgttt gctataatgt aagtggatac
    24301 aaaaacgaaa agatgcagga ggaaatggta atatgggaaa attaggaatc tcgatttatc
    24361 cagaacggtc aacatttgaa aaggacaaag cgtacttgga tttagctcat aagtatgggt
    24421 ataaacgggt ttttaccagt ttgctgcaga tcaatgatga taaagaaaaa gttctttcag
    24481 aatttaaaga agtagttgat tacgcgaata gcctaggcat ggaagtaatg gttgatatca
    24541 atccagcgtt atttgaacag ttggagattt cttacgatga cttatctttt ttccataaga
    24601 tgggtgccta cggggtccgc ttagatatcg gattcacagg agcagaagaa gcaaaaatga
    24661 cgcgcaatcc ttttggtatc aaaatcgaga tcaatatgag ttcgggcacg aattacgttg
    24721 acaacatcat gagttattcg ccaaacacgg ataatttatt aggttctcat aatttttatc
    24781 ctcatcgata ctctggttta ggatacgaac actttgtttt ttgttcagaa aaattcagaa
    24841 aatataattt gaatacgatg gcattcgtca attcgcaatc tgctgagttt ggcccttggc
    24901 ctacgcaaga tggcttgtgc acgctggaag accaccgaga tcttgaaatt gcgacacaag
    24961 tgaagcattt aatccttaca ggattgattg atgatatttc tattggaaat gcgtacgcaa
    25021 gtgaagaaga attgaaagaa atggcagaag catttaacgc ggattatcca acattgaaag
    25081 tagatacgga agaaggtatt acagaaaacg aacgaatctg cttgtttgat aaccttcata
    25141 gttatcgagg ggatcgctca gaatatatcc ttcgttcaac gatgactcgt gtatactaca
    25201 aagataaaga tttcccgcct cataatacgc gagatatgca tcatggggat gtactgattg
    25261 acaatgaagg gtacggtcaa tacaaaggag aaacacaaat cgccttgaag gatatgaaaa
    25321 acgacggacg tgtcaatgtt gtaggaagaa tctccgatga cgaattattc ctccttgact
    25381 ttttgaaacc atggtcaagc tttaaattaa ttgaaaataa aaaatagata attagttatt
    25441 gcagaaataa tccgctagaa
//
LOCUS       DAZUJR010000039        25124 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.039, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000039 DAZUJR010000000
VERSION     DAZUJR010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25124
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.039"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            6..245
                     /locus_tag="ACG804_001487"
     CDS             6..245
                     /locus_tag="ACG804_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832423.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKEVFKALSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            312..521
                     /locus_tag="ACG804_001488"
     CDS             312..521
                     /locus_tag="ACG804_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832424.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKTMKQKHLKRLSVAQYINDMQLT
                     GKEKACLLGSMKNFEQLRRTYRIHF"
     gene            581..1252
                     /locus_tag="ACG804_001489"
     CDS             581..1252
                     /locus_tag="ACG804_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HFS4832425.1"
                     /translation="MKKWLFGFLGVTLIVFCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVLAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPEYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            1305..3281
                     /locus_tag="ACG804_001490"
     CDS             1305..3281
                     /locus_tag="ACG804_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFS4832426.1"
                     /translation="MAINRYVKKAGMLIGMLGIIAGCFQGYRAYAEDITQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PTEDSDLTNAKVDEIVKDVEDKGSNSEYVKNATNKITSAVDENGEITFADQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDNTGSGFLKDIHLYPKNIVSKLSFELTK
                     FGDDGTAQSKQTPLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDKEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDTA
                     GQGLSYVAAKANIKVTNKDGSVVLKENTDYKIQNSENGFVIDFIVNNGQVSDTVASLH
                     GQDLQMTYNMYVNDSAAVANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLVDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGEYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQTYVLISCLLLGAGALSAVVYFKKKA"
     gene            3296..4048
                     /locus_tag="ACG804_001491"
     CDS             3296..4048
                     /locus_tag="ACG804_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFS4832427.1"
                     /translation="MIIRKPKKKRIMGKWIIAFWLLSAVGVLLLMPAEASVAKYQQNQ
                     QIAAIDRTGTAAETDSSLDVAKIELGDPVGILTILSISLKLPIYDGTSDKILENGVGI
                     TEGTGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGEKFYIKVDGEQHAYQIDRIE
                     EVQKDELQRNFVTYLESNPNEDRVTLMTCTPKGINTHRFLVYGKRVTFTKSELKDEEN
                     KKQKLSWKWLLGSTVFLSVMIIGSLFVYKKKK"
     gene            4064..4819
                     /locus_tag="ACG804_001492"
     CDS             4064..4819
                     /locus_tag="ACG804_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
                     /protein_id="HFS4832428.1"
                     /translation="MRNRKWLFVCAAALFSFTAYTQLTFADRQESTDSTEQTIQTSDS
                     STIQSSDETVDSSTVDSSEEPKIAEDDQIVKQTIHVQKIISSEQLDNQGHEKQEGVNG
                     AKFSVYDVSDILQKMDVKDLTTDQIESQLKNRVKKLSSDQLKLVSNEETKTIDQQTGV
                     FEFSVEVQANQKQAYYIVNESSPENISNSEDILLLTPVSDKNGEFLKDVWIYPKSEAS
                     QPKEEVKKIVSTGVKKNFFENCWDFVTHLFSRD"
     gene            4832..5092
                     /locus_tag="ACG804_001493"
     CDS             4832..5092
                     /locus_tag="ACG804_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832429.1"
                     /translation="MKLIKLLLFNFSCLTAVFLYCGLLFSKLSILPSYQLYLMRILNI
                     PAASMPLDIMEKLIRNPLFTTINLIVIVGISLVIYKKEGMKG"
     gene            5089..7179
                     /locus_tag="ACG804_001494"
     CDS             5089..7179
                     /locus_tag="ACG804_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HFS4832430.1"
                     /translation="MNFKHSWTRRLKYVFPIMMMLGTLFGLKTANVFAEKVIVDPSNP
                     IQNVKNNFIIPKDVPNAKTNITVNGASKVYKYHVDANKGGFTDDYVGLVEGNKNIRYP
                     SFQKEYGETNLVLEGVTTNTKVNIDYGKIGTYNGKKVNIKLVLSNIHLYSDTLPWNLL
                     DNNYTKTHFRDDGYKNTNGAMSKSKKRTVLWISDNLFSGIVYHSTQMNVQLVATYEDG
                     SPVQFSGDTFISFNSLNPAGGKSTDLKGEYAHYDKMNTTDWYVRKDTVLSEFKSFYNN
                     LNVVGGHPGGSSKLTQADNDFNNLHDKLGDPKFGQGTVSFKISEANPTFVIGSSNVQT
                     WFTLSSATIFSVVPDQPEKTGVDKNGNNVNDKMLQVGDTIQYRIKQKVNRLGVDLLAV
                     YDRFELIDNLPKEVNYVDAHVESGTNKKFDVSGEVTYDKTKHQVKYAAKADTLKNRMK
                     YNGETYELVINVKVNELANQNSVAKNQGTSIINKVEKDTNIITVYFPKIPVKEVQQNG
                     KDVNGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDAASDHYKQFSIQDPIEARLT
                     YKEGSAQVIDKSKGKDITSEGTLTYDSNSRTLKWEASADFLSNNLLDGREIQLIFTAK
                     TPLQSEKNIDNQAVVAVDNVSNKTNVVTIGVDPNLPQVIVPKTGSTHLVTISAVSLLL
                     LVLATFSYAVLRYI"
     gene            7206..7670
                     /locus_tag="ACG804_001495"
     CDS             7206..7670
                     /locus_tag="ACG804_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832431.1"
                     /translation="MKKLIIVVTSLIAMIVILVGCSNEKNKQTNQDNGVLKSGTMWKE
                     EVGGLVYNLKIIDETTWEYSESVWHPDPVQITVKRQKDYKGLERYKIVDSAGVREFIN
                     KSDSLFIVVPYEKNGVKKIIFLGSSKDEKRTKEKLIHDGSQSNKYKLQKTSE"
     gene            7667..7909
                     /locus_tag="ACG804_001496"
     CDS             7667..7909
                     /locus_tag="ACG804_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HFS4832432.1"
                     /translation="MIASLFICPEGGITVAKAKTPFEKAASKILERRGVSETQWKQEV
                     LEKAQFDLLRGKDKDLEGYIYQREREKLVFDEIIKH"
     gene            7927..8229
                     /locus_tag="ACG804_001497"
     CDS             7927..8229
                     /locus_tag="ACG804_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832433.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAAAA
                     VASIVIGGLFFLFGRRGAENGKMHVGYVLMGVGVILAAASIVVSLFGLFGQTPQGL"
     gene            8299..10362
                     /locus_tag="ACG804_001498"
     CDS             8299..10362
                     /locus_tag="ACG804_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832434.1"
                     /translation="MYFTIAGNTKTDKELIKKATKEVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGKVLEHESRSSVKLTLTLHDTEGKIEKAGTEYVFGPLDYQISEGFYPTLMDLIR
                     LDVFKETDETMSVEESYRNEKLLQVLEEELESDQRKVNQGSEVEVNEEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETAEVEVDPVEA
                     NEESTWTEGDSQEYIEPLISEEVEKNEIEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKAKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCVA
                     KINNFTQTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMEKYEKIQQELQVQIPKWKKEYEIQQQELKEQEEKQRQKEKEREQLELKKREQD
                     LAEQQMAIEKQRLNQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPTPSVAAVQTPM
                     NNQTNLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTTSIKEE
                     AQEQARKEYEQQLEELLNRTNQSTTESSMENSKESDSSKAKEGSSDSTVQSNTSESSE
                     SNEVK"
     gene            10362..12974
                     /locus_tag="ACG804_001499"
     CDS             10362..12974
                     /locus_tag="ACG804_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirD4-like conjugal transfer protein, CD1115
                     family"
                     /protein_id="HFS4832435.1"
                     /translation="MRVRETTKRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     KKIFYSGLVYLPLEYLVTRVPEVFNRLEIVKGSLQGINLFQLQEMPQVFHFDSAGFWN
                     PFTPTTSLGTRLAISTVCVVPAVLMGLKMDMWFRPLADGQKGDNRLMTLKEIQQIYPQ
                     IPETKTTFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     KQSSMVVNDPKTELYVGSKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPDNEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSVGFPKYLDLKLHESLLNQRVVVEFYHKGK
                     KFHEERVKVGYKGFCEINFDCHLVAGDQVCLKYDHQGKEYVAWYEFSQRVLKDEEGNI
                     VYRKKRGETHLPELEKEAVLTLDEEKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNML
                     WDLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENS
                     TINSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNH
                     GETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDEYARNLYHGL
                     HDQLEEKNEENMFYKIVQSLENETAKKLLIQFYEEQAADRLQEYVEKLIKNKEISEMI
                     GKRLLLESEKVVKE"
     gene            12971..15502
                     /locus_tag="ACG804_001500"
     CDS             12971..15502
                     /locus_tag="ACG804_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pLS20_p028 family conjugation system
                     transmembrane protein"
                     /protein_id="HFS4832436.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDANPKTVTKVLQDYGNYLQYQDV
                     FSWIWNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNALFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKSFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PKQAKEMADKDKSGLSDLQKDRLRALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYR
                     RYSSKPGIILAGESSLAVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSA
                     IEDISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIALFKGSQ
                     SVTKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGF
                     GHRKDVTPDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGT
                     AEDLTEKAKDTLEEKLDGTRAKELAEAVKNPSEALEKQKEKASEVKEGLKDAYGEGQV
                     NAAVKANTTTEKENQEGIVIPSVKDHQEALHSNENSIEEKNSIEERNSEEGKNGQLPK
                     TDPEQYRYKPNSDLENEKRISDLSKVNQEDKAENEGQLPKTDPEQYRYRSVNSENEKR
                     ISDLPKRNQEVQTDEDSIVLPNDNGIEVGTEKSTKIGLPKAQNLPMKDSRLNQFKEND
                     QSFVHQSTAGTVQMKPSRLPENGNLTTVSYNLSESGETGNASVQNVVTREAAPKPIQN
                     VHTGYKPANVAFTAPTKINVTRETKNRNNALKEQLLRDIKQDIKP"
     gene            15552..15884
                     /locus_tag="ACG804_001501"
     CDS             15552..15884
                     /locus_tag="ACG804_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832437.1"
                     /translation="MDKYINMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKMVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFADKNHYHALDPNRNY
                     HGTYKEDE"
     gene            15885..16478
                     /locus_tag="ACG804_001502"
     CDS             15885..16478
                     /locus_tag="ACG804_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832438.1"
                     /translation="MRVKGQNSVERKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLKKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            16641..18665
                     /locus_tag="ACG804_001503"
     CDS             16641..18665
                     /locus_tag="ACG804_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4 family type IV secretion system protein"
                     /protein_id="HFS4832439.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTETQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNAINPDFIETVNYVTNFQ
                     REMRKVEAMTVLATQSPQEMVPENMSSDNFSKLKKVFEFSSTKIFMRMDESILRHIEG
                     LVGKSMTNSELESIPQQNQGDAVINFGSKETIRVHFSPNKRQLKLFDGGK"
     gene            18665..19864
                     /locus_tag="ACG804_001504"
     CDS             18665..19864
                     /locus_tag="ACG804_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFS4832440.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWVFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYKLL
                     PSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKFPN
                     SKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSAYYKNCMSII
                     NTNKLMEYDEFAIKHWREGGGTGGTITGSWGNPFPGSSLDKNSFSGGQLFGKNPGGEF
                     RPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVYQE
                     FANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDPLP
                     FLNSSKK"
     gene            19880..20524
                     /locus_tag="ACG804_001505"
     CDS             19880..20524
                     /locus_tag="ACG804_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832441.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQETNTYKIEEVAK
                     NASDKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPADDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVTDFSYFTR"
     gene            20535..21341
                     /locus_tag="ACG804_001506"
     CDS             20535..21341
                     /locus_tag="ACG804_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832442.1"
                     /translation="MSKKKGARQRFKKRKSYLRWLGIFMILGFLILASPIYTHKKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIKAKVIKVSDDYFVVKLAHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQMKDQEEIIQKLQEKIDRMTKEKI"
     gene            21363..21593
                     /locus_tag="ACG804_001507"
     CDS             21363..21593
                     /locus_tag="ACG804_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832443.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYVAAKKYFTADNK"
     gene            22107..22415
                     /locus_tag="ACG804_001508"
     CDS             22107..22415
                     /locus_tag="ACG804_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832444.1"
                     /translation="MEVRIRNVDEKIVREIDRRCDELSNRTGNKWSRNDYLKLLVEND
                     FDRPLMEYKQDKFDQLLNQLIDKFSFVQSHNTKVLEEYICQNNQIIELLIEQSRGGEV
                     "
     gene            22417..22839
                     /locus_tag="ACG804_001509"
     CDS             22417..22839
                     /locus_tag="ACG804_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832445.1"
                     /translation="MAKVIDKHIYFYETHIDVLDEIIATHAEVKNYSEAVRFLCMNYD
                     SEVEKKVNSNQAKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKANQTKKYSPKIKKTISESVTTKSEVFDPTRFLKR"
     gene            22859..24448
                     /gene="mobP2"
                     /locus_tag="ACG804_001510"
     CDS             22859..24448
                     /gene="mobP2"
                     /locus_tag="ACG804_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobP2 family relaxase"
                     /protein_id="HFS4832446.1"
                     /translation="MSKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEKERRTPEE
                     EQELRLIKNALEDFYIPEGETFSESKTGKEFSETSNEAQSLMKHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKVLTHSEQKEYQRLNQAIKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQTFQRGQQKGSIIYQDVVSHDHSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKKNTRKPYTEIENGVSYIVPKG
                     KRRQATLDEMKTNYVHELERFSYEKNRMGMEKRNLLTRKSDLRNTLTKVVKEPVRYDR
                     HAMSLLTEVYKNLPKKRSEWHYGDENRTKLSPYTREKLDELTQYVLTKEPGYQEYIQI
                     SKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKKQDSQIKPLIERMDQ
                     MQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEEK
                     YHASKAYEEQQRRIQMEQERQ"
     gene            24460..24795
                     /locus_tag="ACG804_001511"
     CDS             24460..24795
                     /locus_tag="ACG804_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832447.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLINEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKSI
                     EESISLTEC"
     gene            24936..>25124
                     /locus_tag="ACG804_001512"
     CDS             24936..>25124
                     /locus_tag="ACG804_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832448.1"
                     /translation="MAYSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQSGDI
                     LTLNLTTKTFVDAAEDYPF"
BASE COUNT         9386 a         3904 c         5155 g         6679 t
ORIGIN      
        1 agtagatggc gcgaccagtt ttagaggcga tggatatgga tactttgaca aaaggaaggt
       61 atgtacagct gttagctcgt ggttattcac ctaaagaagt attcaaagcc ttatctaaag
      121 gaacagatat ggaaaaagaa agattgcgaa aagaattcga ttattggaga acccataatg
      181 gaatcaagga tttgaaacca gcacggccag taattaaacg aaagaaaaag ataacccaag
      241 actgaagtgt agagcgtatg tgatcatagg cttttttatt tttgcaaaaa acaaggaagg
      301 taggaaaact catgaattat gaagaaatcg aaaacagaaa aaaagtgtcg aaagaaatgg
      361 aagaaaagtt actaaaaacg atgaagcaaa aacaccttaa aagattatct gtcgcgcaat
      421 atatcaatga tatgcagtta acaggaaaag agaaagcttg tttgttaggt tcaatgaaaa
      481 actttgaaca gttgagacga acttatagaa ttcattttta aaactttttc tatggaaatg
      541 agaaaaagtt tttttgtttt gtctgaaagg aggcagatgg atgaaaaaat ggttatttgg
      601 ttttttagga gtcactttaa tcgtcttttg cagtgtgttt ggctatgtta gctaccaaaa
      661 acatgaagga gaggtgttta agcaaaatat agaaaaaaag atgcccgtag atcaaatcaa
      721 tgcacatgca aagagttata aggaggatgc aacgaacgtc aataatgata tgtctttggg
      781 gcaaatgttg tccatacaaa aagaagcaat cgaaatgggc gtcaataaac aagtacttgc
      841 acaaattcag attcctgcac ttggtttagc attgccaatt tttaaagggg caaatcaata
      901 cactttgagt cttggagcgg ctacttattt ttatgaagat gccgaaatgg gcaaaggaaa
      961 ctatgtccta gcaggtcata acatggaaat gccaggtgtt ttattttctg atattcagaa
     1021 gttgtcatta ggggaggtga tggacttagt tagtaacgat ggcgtctatc gttacaaggt
     1081 aacgcgtaaa tttatcgtac ctgagtactt taaattaatc gatggcgttc ctgaagagaa
     1141 ctctttcttg tctttgccaa agaaaggaga gaaaccctta ttaacgttgt ttacttgtgt
     1201 ctatacgtca caaggaaaag aaagatacgt ggtacaggga gagctacaat aacaaggttt
     1261 taatcaacgc gagtcgttga aatatgaaat gaggagagta aaaaatggca ataaatcggt
     1321 atgtaaaaaa agctggaatg cttattggaa tgttaggaat cattgcaggc tgctttcagg
     1381 gatatcgagc atatgcagaa gatatcacgc aaaaaacgcc accagaaaag gtcaatatca
     1441 cggttcataa attaatgtac gatcaaggaa cgcaattgaa tgttgatatt gacgggatca
     1501 aaaacgatgg ttatacgcac gatcaatatc ctacaggtgt aacgaaatac aacaaggcag
     1561 attatggtga tgttgagttt acgttaggaa atattacgga tcaagtatta ccgactgaag
     1621 attctgatct aaccaacgcg aaagtggacg aaatcgttaa agatgtagaa gacaagggat
     1681 ctaacagtga gtacgtcaag aatgcaacaa acaaaattac ttcagctgta gatgaaaatg
     1741 gtgagattac ttttgctgat caaccagcct atgtcaattc caaagggaat gtatatgtgg
     1801 tttatgaaag taaatccgct gctggattag tcacacaaaa agcaaaacca atggttgtga
     1861 ttgcgccaat gactgataat acaggttcag gttttttaaa agacattcac ttatatccta
     1921 aaaatattgt ttctaagttg agttttgaat taacgaaatt tggtgacgat ggcacagctc
     1981 aaagcaaaca aacaccttta aaaggggcaa aatttgagtt atacaagggc gaacctggaa
     2041 aaggaacaaa attaggagat cttgtatcgg atgatcaagg aaagctgact gctactgatt
     2101 tgacgttagg aaaatactat tttgtggaag ttccttcaga agttgtagtg ggatcagata
     2161 aagaaccaac agcagatcaa tatttattag gcgcagacgc tcgcaacgat gcgcacaata
     2221 aattaacctt tgaaattacg aatgatggcg tgacaagtga cttaaaagct tcatacgtaa
     2281 actataaagc accagtgatc gataaaacag taacaaatgg aacaggacaa gaacattctt
     2341 tccaaattgg tgacgcagta aattatcaag gaacaattca tatcccaaca gacattgcag
     2401 gcggagcaga cggtatcaca gtaaacggag tgaaaagcga aacttctcct tacagtgtat
     2461 ttaaatgggg ggatacagca ggacaaggac tttcttatgt cgctgctaaa gcaaatatca
     2521 aagtaacaaa taaagatgga tctgtggtat taaaagaaaa tacagattat aaaatccaaa
     2581 attcagaaaa tggctttgtg atcgatttta tcgtgaataa tggccaagta agtgatactg
     2641 tagcaagttt acacggacaa gatcttcaaa tgacttataa catgtatgta aatgacagcg
     2701 cagctgttgc caatccatta acaaatagcg tggatttcgt ttataacaac aatccattta
     2761 atcaggaaga acaccacgaa aaaacgaaag ctgacgttgt gacttatggt gcaaaattct
     2821 taaaagtcga tagcggacta tttggaacag gaatcaaagc aacaccgctt gaaggcgcag
     2881 aatttgctgc taaaaacgca gaaggaaaat attatggtgg attagttgat acggataaag
     2941 acggtgtcaa agaagcagta tgggtagacg atgtagcaaa tgcagcgatc ctaaaatcag
     3001 ataaagaagg tcactttgaa atcactggtt taactgaagg tgaatattca ctggaagaaa
     3061 caaaagcgcc tgaaaactat caaaaattaa cgaaagagat ctctttcaaa gtagacaaag
     3121 attcatacaa agaagaaaac cgaatcacga tcaaaaacaa tcaaaaagct tccgtaccaa
     3181 tgaccggtag caacggtttt caaacgtatg tattaatctc ttgcttgttg ctaggagcag
     3241 gggcactttc tgcagttgtt tactttaaga agaaagccta gaaggatcaa aaccaatgat
     3301 tatcaggaag cctaagaaaa agcgaatcat gggtaaatgg atcattgctt tctggttact
     3361 ttcagctgta ggtgtcttac ttttgatgcc tgctgaagcg agcgtggcga aataccaaca
     3421 aaatcagcag attgccgcaa tcgatcgaac aggaacggca gcagaaacgg attcttcttt
     3481 ggatgttgct aagattgagt taggcgatcc tgttggtatt cttacaattc taagtatttc
     3541 tttaaaacta ccaatttatg acggaacgtc cgacaaaatt ttagaaaatg gtgtaggtat
     3601 tacggaagga actggtgata ttacaggagg aaacggtaaa aatcctttaa tcgcaggtca
     3661 tagtggactt tataaagata atctttttga tgatttacct tcagtaaaaa agggagaaaa
     3721 gttttatatc aaagttgatg gtgagcagca cgcttatcaa atcgatcgga ttgaggaagt
     3781 gcaaaaagac gaactacaaa gaaactttgt cacttactta gaatcaaatc ccaatgaaga
     3841 tcgagtaacg ctaatgacat gtacgcctaa ggggatcaac acacaccgtt ttctagtgta
     3901 tgggaagcga gtaaccttta caaaatcaga attaaaagat gaagaaaata agaaacaaaa
     3961 attatcttgg aaatggcttt taggaagtac tgtttttctt tcagtcatga tcattggttc
     4021 gctatttgtt tataaaaaga aaaaataaag gagggtaacc aacatgagaa atagaaaatg
     4081 gctatttgtt tgtgcagccg ctcttttttc tttcactgcc tacacacagt tgacgtttgc
     4141 agacagacaa gaaagcacgg atagcacaga acaaacaatc caaacgtcag atagcagcac
     4201 gattcaaagc agcgatgaaa ccgtcgattc gtcaacagtt gattcttcag aagaacctaa
     4261 aattgctgaa gacgatcaaa tagtcaaaca gaccattcac gttcaaaaga ttatttcttc
     4321 agaacaatta gacaaccagg ggcatgaaaa acaagaagga gtaaatggcg cgaagttttc
     4381 tgtttatgat gtatcggaca ttttacaaaa gatggatgtt aaggatctca ctactgacca
     4441 aattgaatcc caattaaaaa atcgagtgaa aaaactatcc agtgatcaat tgaagctagt
     4501 ttctaatgaa gaaacaaaga caattgatca acaaacaggt gtctttgaat tctcggtaga
     4561 agtacaggca aatcagaaac aagcttatta tattgtcaat gaatcaagtc ctgaaaacat
     4621 ttctaatagc gaggatattt tgctattaac acctgtttct gataaaaacg gtgaattctt
     4681 aaaggatgtg tggatctatc ctaaatcaga agcttcgcaa cctaaagaag aagtaaaaaa
     4741 aatcgtttct actggcgtaa agaaaaactt ctttgagaat tgttgggatt ttgttactca
     4801 cttgttttct agagattaag gaagaaataa aatgaaactg atcaaattat tattattcaa
     4861 tttttcttgt ttaaccgcag tctttttgta ctgcggttta ttattttcta aactatctat
     4921 tttgccaagc taccaactat acctaatgag gattttaaac ataccagctg cttccatgcc
     4981 gctagatatt atggaaaagc tcattaggaa tccattattt actacgatca atttgatcgt
     5041 tattgtcgga atttcactag tcatttataa aaaagagggg atgaagggat gaattttaaa
     5101 cactcgtgga caagacggtt aaaatatgtt tttcccataa tgatgatgtt aggtacattg
     5161 tttgggttaa aaacagccaa tgtctttgct gaaaaagtta ttgtcgatcc gtcaaatcca
     5221 atccagaacg taaagaataa ttttattatt ccaaaagatg ttcctaatgc aaaaacaaat
     5281 attactgtaa acggagcgtc aaaagtttac aaatatcatg ttgatgccaa caaaggtggt
     5341 tttacagacg actacgtagg attagtggag ggaaacaaaa atatacgcta tccttctttc
     5401 caaaaagaat acggtgaaac aaaccttgtt ttagaaggcg taacaaccaa caccaaagtc
     5461 aatattgact atggaaaaat cggtacgtat aacgggaaaa aagtcaatat caagctagtt
     5521 ctatctaata ttcacttata ctcggatacg ttgccgtgga atctactaga taacaactat
     5581 acaaaaactc attttcgaga cgatggctat aaaaatacga atggtgcaat gagtaaatct
     5641 aaaaaaagaa cagtactttg gatctcagac aatcttttct caggaattgt ttaccattca
     5701 acacaaatga atgtgcagct agtagccaca tatgaggacg gtagccccgt tcaattttca
     5761 ggagatacat ttatcagttt taactctttg aaccctgcag gaggaaaaag cacggatctt
     5821 aaaggagaat atgcccacta tgacaaaatg aatacgacag attggtatgt cagaaaagat
     5881 acggttcttt cagaatttaa atctttctac aacaatctga acgtggtagg tggccaccca
     5941 ggaggaagct ctaagctgac acaagcggat aatgatttca ataatttgca tgataaatta
     6001 ggagatccga agtttggtca aggtactgtg tcctttaaaa tatctgaagc aaatccgacg
     6061 tttgtgattg gttcttctaa tgttcaaacc tggtttactt tatcttctgc gacaatcttt
     6121 agtgttgttc ctgatcaacc tgaaaaaaca ggggttgata aaaatggaaa taacgtgaac
     6181 gataaaatgt tgcaagtagg agacacgatt caatatcgaa tcaaacagaa ggtgaatcga
     6241 ttaggagtgg atttactagc ggtttacgat cgatttgagt taatcgataa tttaccaaaa
     6301 gaagtaaatt acgtcgatgc acacgttgaa agtggtacaa ataaaaaatt cgatgtatct
     6361 ggtgaagtga cctatgacaa aacaaaacac caggtaaaat atgcagcgaa agctgataca
     6421 ttaaaaaatc gaatgaagta taacggcgaa acttacgaat tagtgatcaa tgtaaaagtc
     6481 aatgaattgg ccaatcaaaa tagtgtagcc aaaaatcagg gaacgtcgat cattaataaa
     6541 gtagaaaagg atacaaatat cattaccgtt tatttcccta aaattccagt gaaagaagta
     6601 caacaaaatg gaaaagatgt aaacggacga aatgacggta agaagggtac gccgacagct
     6661 cctttaaacg caggatctga agtacaatat ctagtcacac aaaaatggca cacaaaaggc
     6721 gtagacgctg cgtcagatca ctacaaacaa tttagtattc aagatccaat tgaagctcgt
     6781 ttgacatata aagaaggttc tgcgcaagta atagataaga gtaaaggaaa agatattact
     6841 tctgaaggca cactaaccta tgatagcaat tcaagaacgc tgaagtggga agcttccgct
     6901 gacttcttaa gtaacaatct tttagatgga cgagaaattc agctgatatt tacagctaaa
     6961 actccattac aatcagaaaa aaatattgat aaccaagccg tagtagcagt agataatgtt
     7021 tctaataaaa caaatgttgt gacaattggg gttgatccta acttgccaca ggtcattgtt
     7081 cctaaaacag gttctacaca tttagtaacg atttcagcgg tcagcttact attacttgtg
     7141 ttagcaactt ttagttatgc ggttctgaga tacatttaaa ataaaaaaac gaaagaatga
     7201 ataaaatgaa aaagttaata atagtagtta cttccttgat tgccatgatt gttattttag
     7261 tcggatgtag taatgaaaaa aataaacaaa ctaatcaaga taatggcgta ttgaaatcag
     7321 gaactatgtg gaaagaagaa gtaggtggtc ttgtttataa tttgaaaatt atagacgaga
     7381 ctacctggga atactctgag agtgtatggc atccagatcc tgtacaaata acagtcaaga
     7441 ggcaaaaaga ctataaaggt ttagaaagat acaaaatagt agattcagct ggtgttaggg
     7501 aatttataaa caaatctgat tctttattta ttgttgttcc ctatgagaag aatggcgtaa
     7561 aaaaaataat ttttcttgga tctagcaagg atgaaaagcg aacgaaagag aaattgattc
     7621 acgatggatc acaatccaat aaatataagt tacaaaagac tagcgagtga ttgctagtct
     7681 ttttatttgt cctgaaggag gaatcacagt ggcaaaagct aaaacgccat ttgaaaaagc
     7741 cgcgtctaaa atcttagaac gccgcggtgt atctgaaaca cagtggaaac aagaagtcct
     7801 tgaaaaagca caatttgacc tattacgggg aaaagacaag gacttagaag gatatatcta
     7861 tcaacgtgaa cgtgaaaagc ttgttttcga tgaaattatt aaacactaaa aggagcgaac
     7921 aattttatgt ttgaatcaat tacaatgaat tttttaacac aaccgaaagt agtagctgcg
     7981 gttgatattt ttagagcatt acaaactgcc gcaactagtt taaaaaacaa tctgatgatt
     8041 tttgctgctg ctgcggccgt tgcttccatt gttattgggg gtcttttctt cctatttgga
     8101 cgaagaggag ctgaaaatgg gaagatgcac gtaggctatg tattgatggg ggtaggagtt
     8161 attttagcag cagcttctat tgtggtttcg ttatttggat tgtttggaca aacacctcaa
     8221 ggattataag aaagtaaaaa agtaggagta agaagtagtc gatacttttt actccttttt
     8281 tatgaaagga gaatactcat gtactttacg attgcaggca ataccaaaac agataaagag
     8341 ttaataaaaa aagcaacgaa ggaagtagga aagcgtactt cttttttacc gaaaacaatt
     8401 aaatattctg tcattgaaac ggaagaacag ctacatgtgt tagggaaagt actggaacac
     8461 gaaagtcgat cttctgttaa gttgactctc acgttacatg acacagaagg aaaaatagag
     8521 aaagctggta cagaatacgt ttttggccca ctggattatc aaatttcaga aggtttctat
     8581 cctacattga tggatttaat ccgccttgat gtgtttaaag aaacggatga aactatgagt
     8641 gtggaagagt cttatcgaaa cgaaaaactt ttacaagttt tagaagaaga gttagagagc
     8701 gaccaaagaa aagtgaatca agggagtgaa gtcgaagtaa atgaagaagt accatgggaa
     8761 cgaccaatat ttccaaagaa ggagtcaaaa gaaaaagaga cagtctatgt tgacgaacaa
     8821 gctgatattc cgactcagaa atcgatattt gaggaagaga acgatgtgat gggtcaattg
     8881 gaggtagatc cctttgaaga aacaatggag gatgaagaga cggccgaagt agaagttgat
     8941 ccagttgaag cgaatgaaga gtcaacatgg actgaagggg attctcagga atatattgaa
     9001 ccacttatca gtgaagaagt agaaaaaaac gaaatagaga tacaaaaggc aactgtattt
     9061 gattatattt tggatcaata tccgccagag catgaatgga tgaaagaaaa aaacaaatta
     9121 tttttaaatg agctttattc gaaatatcaa ttaccccaaa cctatcaagc atttttagag
     9181 agtaaagaag aattaatctc acagggtaaa ggcacacttt tagaacagtt agagtctgtc
     9241 caatcaacaa attggcatga gcttgcacaa gaagatttat tagccacctt tgaagaacgt
     9301 caacaagaaa cagatcaaga aattaatgag tatgcgacgg aacagtcgtc taattgggag
     9361 aaagcaaaag aggaactaaa taaagaagaa cagcgagtga ttgaagaaga agtacaaaaa
     9421 attaaagagc gatacgaaaa gaaacgcgac aatgcgtatt ccttgtgtgt agcaaagatc
     9481 aataatttta ctcagacgaa tcaagaagcg ttatcgaaag aaaaagaaaa cttgttaaaa
     9541 gaacgtatta aagaacgaaa agaagaattt taccgaggtt tgcgtacaga taagctaaag
     9601 attagcaaag aattaaatga acaactgaat aagctatatc aaacaacgac tgaagttctt
     9661 atggaaaaat acgaaaagat ccagcaagaa ttacaagtgc aaattccaaa atggaaaaaa
     9721 gagtatgaaa ttcaacaaca agaattgaaa gaacaagaag aaaaacaacg gcaaaaagaa
     9781 aaagagcgcg aacaattaga actaaaaaaa cgtgaacagg atcttgcgga acaacaaatg
     9841 gcaatagaaa aacaacggtt aaaccaagaa aaggaaaaag aagcagctgc tcgtaaggaa
     9901 cgtcaagaac aaatggatac attgcgacaa gctcagttaa attatctagc acaacctcaa
     9961 ccaacgcctt cagtagctgc tgttcaaacc ccaatgaaca accaaacaaa tctaactcct
    10021 tcaccacagc gttcctttaa cggatggatg gtgggatgta ttgcaagttt aagcttgctt
    10081 ctaggtggag gaacagtatt tgcttttaat catatcaatc aatcttcaca ggctgattct
    10141 gtggccacaa cgacgtcaat caaggaagaa gcccaagaac aagcaagaaa agagtatgaa
    10201 caacaattag aagaattatt gaatcgtacc aatcagtcaa caacagagtc aagcatggaa
    10261 aatagcaaag agagtgattc tagtaaggct aaagaaggat caagcgattc aactgtacaa
    10321 tcaaacactt ccgaaagttc agaatcaaat gaggtgaaat aatgcgtgtt agagaaacaa
    10381 cgaagcgaaa agacaaacga ttcaatttag aaaagaatag gtatctttct catttctatc
    10441 gctatactcc ctcaggagaa gagctaccag aaaaacatga caaacgcatt tcgaaaaaga
    10501 ttttttatag tggacttgta tacctccctt tagagtattt agtaacaaga gtaccagaag
    10561 ttttcaaccg attggaaatt gttaagggaa gcttacaagg aataaatctg tttcaattac
    10621 aggaaatgcc acaggtcttt cattttgatt cagctggttt ttggaatcca tttactccta
    10681 caactagttt gggtacacgt ttagcaattt cgacagtttg tgtggttcca gctgtactta
    10741 tgggattgaa aatggacatg tggtttcgtc ctctagcaga tggacaaaaa ggggataatc
    10801 gattaatgac cttaaaagaa atccaacaga tttatccgca aatacctgaa acaaaaacta
    10861 cttttccagg ttatggaggt attccaatca cacattacaa aaaatattgg tacattcaaa
    10921 cagatactgt taatacgtgt attgttggta cctctcgatc agggaaaggt cagattgaag
    10981 tgttagccac cattgacaat ttatctcgtg cagaaaaaca aagttcaatg gtcgttaatg
    11041 atccaaaaac agaattatat gttggtagta aagatgaact agaagctaga gggtatgatg
    11101 tatatgcctt taatatcacc gatccactgc aatcaatgag tgataatcca ttggcactca
    11161 tcgtgaaata ctggaaacga ggagacatag atactgcaac acagttaacc aatactttca
    11221 caaatacgat ttattatgat gccaacgctt cagataacaa atactttaac gaaaacgcgc
    11281 agaaagctgt caatgcgctt atttttgcgt tgttagaaca agctgatcaa acaggagatt
    11341 actccaaatt gacaccgaat aatctcgttg agcttctttc tgagattggc ggttttaatt
    11401 attatccaga tccagacaat gaattcaaac agttgaatgc cttagatgaa tttatgaatc
    11461 agttgccacc tggaaacatt gcaaaaaaac aatatggggc aacgaaaatt ggatctgata
    11521 aagcgaaggg aaatatttta tcaacggcaa tcacgggatt gaatccattt actctaacga
    11581 aaattgcaaa gatgacttct caatcaacga ttgattataa atcggttggg tttccaaaat
    11641 acttagattt gaaattacat gaaagtcttt taaatcaacg agtcgtagta gaattttatc
    11701 ataagggaaa gaaatttcat gaagaacgtg tcaaagtagg ctataaagga ttttgtgaaa
    11761 tcaattttga ttgtcattta gttgcaggtg atcaagtttg tttaaaatac gatcatcaag
    11821 gaaaagaata tgtggcttgg tatgaatttt ctcaaagagt attgaaagac gaagagggta
    11881 atatcgttta tcggaaaaaa cgaggagaaa cccatttgcc agaattagaa aaagaagccg
    11941 ttctaacatt agatgaggag aaaagtaact tattagtaga gtctattcgg atgcactata
    12001 ccgataaacc aatggctatt tttatgctta cacctgatta tgatccatct aaccatatca
    12061 ttgttagtat ttttcttagt cagttatata aagaattatc tacgcaatgt gttaagacta
    12121 aaggagataa atgtcaccgc aggattcatt ttattttaga tgaatttggg aatatgccac
    12181 caatggataa tatggaagga atcatgacgg tcacagctgg ccgaaacatg ttgtgggatc
    12241 tgtttattca atcttatcag caactttatg cgaagtatgg agaacaaaac gcagcgatta
    12301 tcaaagaaaa ttgtcagaca catatttata ttatgtcgac agatgataat accatcgaag
    12361 aattttctaa aaaagtgggg aataagacgg ttgaacaaga gaacagtacc atcaattcat
    12421 taggtatgaa tactcatatc aatcgcaatg ttgattcaga tcgtatctta actcctgaaa
    12481 gaatttctac ttttttagaa ggtgaaacga ttgtactcgc tcctttaaaa cgacaagatt
    12541 tgaaaggtca taaaatacgg ccgtatccta tttttaatca tggggaaacg aatcttcctt
    12601 atgcttatca atatattgaa gatttcaatc catcgtggga tatcaatgat atagacatac
    12661 attgtacaca tgcggacttg gatcttaagg ctttacaaat tgattatgat tatttcctac
    12721 cagatgaata tgctagaaat ctctatcatg gactgcatga tcaattagaa gaaaaaaacg
    12781 aagaaaatat gttttataaa atcgttcaat ctcttgagaa tgagacggct aaaaaattgt
    12841 taattcaatt ttacgaagaa caagcagcag atcgacttca agaatatgtt gaaaagttga
    12901 tcaaaaataa agaaatttct gaaatgattg ggaaacggtt gttattggaa tctgaaaagg
    12961 tggtgaaaga atgatcattg gaggaatttt ttctggcata gccgactggt ggtcaggctt
    13021 attcggagaa ggggatgcaa accccaaaac cgtaacgaaa gtcttacaag attatggtaa
    13081 ttatctgcag tatcaagatg tatttagttg gatttggaac acttttctgt ggggattgat
    13141 taaaggatta tataatctca atactttact agaaaaaacc atttatcaaa gctttgattt
    13201 aaaagactta ttgaacgccg ctggggtaaa tgcactattt caaagtttga ttagtaaggt
    13261 attggctctt ttttgtgtcg tcacattaat ttatttaggc ttgaaatttt ttatgagtaa
    13321 acacccacca aaagtcaaaa atatcttggt taatttattt atggccatga tcttgatttt
    13381 tggtgggagt tctttaatcg atgaagggtt aaatatcagt aaaagctttt acggagacgt
    13441 cactgcagca aataaagcag ataaaacggg ttcacctgct tttcaaatta ttcaaaataa
    13501 tgtgatcgat gtcagtacat tactagcaac tgacccgaat aaagtagaat ccctgccaac
    13561 agacaaaaga aatgctttaa cagcgaaaaa ttttaaaaca gcgaatatca atgggattat
    13621 tactcctaaa caagctaaag aaatggcgga taaagataag agtggtttat cagatttaca
    13681 aaaggatcgg ttaagagcgt tacaataccg attggaacta gatgataatg ggaaagaaat
    13741 tcctgttcaa attagtgacg aaggcttagc aaaatatgtc tatacttcag ggtatcgtcg
    13801 atacagtagt aaaccaggta ttatcttagc tggtgaatct tctttggcgg tggcctattt
    13861 atttatccta tttacgatcg ttacttgcat tattgagctg gtatttaaaa aattctattt
    13921 agtgattgcc gcgtcaacgg actttgagac aggccaacgg atgaaaagtg cgatagaaga
    13981 tatttctcaa tccttcttgt tattggcgtt tacgatttta gaattacgaa tctatacatt
    14041 aatgctttca ggtatcggtg atttgcatgc ggcaggaaag atcaatggat tcttgtatgt
    14101 tgttgcttta attgtgctaa ctattgcgct attcaaaggc tctcaatcgg ttacgaagat
    14161 tttcggtgtt gatacgagtc tgaaaaacgg cagtaattct cttcttagca tgtttgcctt
    14221 aggaaatatt gcgaaaaatg tgggtagcgg agctaaaaac cttgcaagtg ctggtaagag
    14281 tggtttaagc catttaaatg atattcgtaa aaatggattt ggccatcgaa aagatgttac
    14341 ccctgataac ggggaagaac aatcagacga taaagctaca actgtaccta atagtaagaa
    14401 aacagtttcc gaaatgttcg ggaaagcgaa aaatggtgtt tctaaagccg cagaaggtct
    14461 tggttacgtc aatgaacgtg ggttaaaagg aacagctgaa gatcttacag aaaaagccaa
    14521 agacacctta gaagagaaat tagacggcac gagagctaaa gaattggctg aagctgtgaa
    14581 gaatccatcc gaagcactag aaaaacaaaa agaaaaagct tcagaagtca aagaaggact
    14641 aaaagatgcg tatggtgaag gacaagttaa tgcagcagta aaagctaata caacaaccga
    14701 aaaagaaaat caagaaggta tagtgattcc ttcagtcaaa gatcaccaag aagcgttgca
    14761 ctctaatgaa aattcgattg aagagaaaaa ttccatagaa gaaagaaatt cagaagaagg
    14821 aaaaaatgga cagttaccaa aaactgatcc agaacaatat cgctataaac ctaacagtga
    14881 ccttgaaaat gagaagcgaa tttcagattt atcaaaagta aatcaagaag acaaagcaga
    14941 aaatgaggga cagttaccaa aaactgatcc agaacaatat cggtatagat ctgttaactc
    15001 cgaaaatgaa aaacgcattt cagatttacc aaaacgaaat caagaagtac aaacggatga
    15061 ggattccatc gttctgccaa atgataatgg aatcgaagtt ggaactgaaa aatcaacgaa
    15121 aattggttta cctaaggcac aaaatttacc aatgaaagat agtcgtttga atcaattcaa
    15181 ggagaatgat caaagctttg ttcaccaatc aactgcaggt actgttcaaa tgaaaccaag
    15241 tcgtttgcct gaaaatggaa atctgacaac tgtttcttac aatttatctg aaagtggtga
    15301 gacagggaat gcgtccgttc aaaatgttgt gacaagagaa gctgcaccaa aacctattca
    15361 aaacgttcat acaggttaca agccagcaaa tgtggcattt actgcaccaa caaaaataaa
    15421 tgtgacaaga gaaactaaaa acaggaacaa tgcattgaaa gaacaactat tgagggatat
    15481 caaacaggat atcaaaccat aaaaggccta caagttaggc cttttattta tatgaaaagg
    15541 agaaatcaat tatggataaa tatataaaca tgaaaaaccc tccaagattt agtggagaat
    15601 ggaagttttt cgcttttttc tttttagatc tattaacgct tggtggctgc tttttttggg
    15661 cgaaaatggt caataatctt gtccacttac cactcttttt tgcactcttg aattatggct
    15721 tatggattgc gatagcgtta gtgattgttt ggcgacccta taataaccca ggtcaacgac
    15781 aaatttttgc gattatcgag tctatttttt ttgcggacaa gaaccattat catgcgttag
    15841 atcctaaccg aaattatcat ggtacgtata aggaggatga ataaatgcga gtcaaaggac
    15901 aaaattcagt tgaaaggaaa tccattttgc agtttggaaa accagaagag cgctctatct
    15961 tggacttatt tccgtataaa tcctgtacag aagagggagt cttaattact agagaagatc
    16021 attttcaacg ttattatcgt gtagtttcta cagacgtgga aggattaaat gaacaagaga
    16081 aactagaacg aatgaatcag ttgaccaccg tcatgcgtac gtatgtgcca acaattaagt
    16141 tagttagttt gaccacagag acggatctaa cggaacaaat cgtgcaaaag cggcaattat
    16201 tagataaaaa tcgtatggaa cagtccttag gaagaaatct acaacgatta aaaaaatatg
    16261 aaaagaaatt agtcgaagaa atccaggaat tgaaacgagc agaacaagaa cgtcctgact
    16321 taagcttctt tttcgtcatt gaaggaaaga caatcaagga tttacaaacc agaaaccgtc
    16381 agttaatgcg atctagtggc attttagggt taaaaccact ctacaaaaaa gaattgatca
    16441 agattctgta tcgaatgaac aatatgaatg atgagtagga atggagaaga gagaatgaaa
    16501 tatccgttga tatggttaga aaaagatgtt ccgaaggaag agaccactag aaaatttcct
    16561 cacactttaa gcctgggtaa gttgggaaaa gggcaatctt ttaaccaagt aaagaatcaa
    16621 acaagaagag gtgactgtac atgttagaag caattaaaac agctttttca ccacaaaatg
    16681 atcaaaaagt acttgatcca ttaaagcaac taggaaatcg ggaaatagaa attttaaaat
    16741 ccaaagggta tgatttagat tttttaaaac aagtgatgcc acaaggtggg ttaaattttg
    16801 atgaagaata tgtgacgtat ggtaatggtt attcacgatg tgtgacagtt tatcactaca
    16861 caaaaaatcc tacgcttttt tggttggcca atctcatgaa caatcctcat acagtggcca
    16921 cactcgatgt tagcacagat gaaaagcaaa aagtgattga tcaaatcaat cgtgccttag
    16981 atgaattaaa tgatcgatca gataatgaac gaaaagcgac tgaccgaaat aaaagcgcag
    17041 aagaatacct ggaactagcg gaatatgctc gtaaattgac ttctaatggg gaaatttcta
    17101 agcaagtcaa agtgagagta catgtttacg gaaacacgat tcaagaagta gatgaacgag
    17161 cgcaggaact gatcgaaaat ctaaaaggga tggattatcg tgcggtgact tatctgcata
    17221 aaaccaaacg agattggcaa tcgatgttta ccatgttcga tgaacaagct gaatggttcg
    17281 gaaatatcaa agggcaatca ctaccatcgt taaacattgg cggaggtttc ccgttccacc
    17341 accaaacgct aaaagatcca ggagggacac aatatgggga aaccatgaca ggcggcccat
    17401 ttgtctggaa tgcgacgtat aaaaatagtg tacggttgtc tactaatacc ttgcttctag
    17461 gaatgatggg agctggtaaa tcgaccgttc ttaaaatgat cgcggaagcc catttagctg
    17521 caggagactt tatttggggc tttgaaaagg gaaaagactt tattcctttc ttaaaggaat
    17581 ataacggtat tatggtgcgt ttagacggat ctgacggaat gatcaatcct ttagagatat
    17641 ttgccacacg gacgtatgat gaagcatcca gtttatatga cgatggatca gtcaaagatt
    17701 tgaagatcaa tgaagcagcg tcctatcaaa cacacttaga caaagtggtc tatcaggtac
    17761 agttagtgag tcctcagcta aaaggaacga tgaaagcaga atttaagacc tacttaaatc
    17821 gtttttatga agagtatgga acagtaccac gcggctttac ttcctcaaat tcgcgttcaa
    17881 atacggagac gcaagtcaca ggtaaagatc cagaagctta tccgacgttc aaagaatttt
    17941 tagacttttt aggacaactg gaattaccag gtgcttccca agagaaaaag aatcgaaaag
    18001 aagaaatgga atccatcgta gaatccttat gtgagacgta tggcatgatt tttgatgggc
    18061 atagtacgat tcgacacctt gaccaacaac agttggtctt ttttgacatt gactctatta
    18121 caggcttaga tcgaggggta caacaatgtc aaatgtacat ggctatgacg ttgatttgga
    18181 atcaggcatt gattcaagga agaagacaac gacgtttaat taaagaaaaa caaatggaag
    18241 aacaagactt caaacgcttc ttggcgatga ttgatgagtg ccataatgcg attaatccag
    18301 attttattga aacggtaaat tatgtcacaa actttcaacg agaaatgcgt aaagtagaag
    18361 caatgactgt tttagctaca caatccccac aagaaatggt gccagaaaat atgtcttctg
    18421 ataacttctc gaaactgaag aaagtctttg aattttcttc tacgaagatc tttatgcgta
    18481 tggatgaatc tattttacgt catatagaag gattagtggg taaatcaatg acgaactcag
    18541 aattagaatc cattcctcaa caaaatcaag gagacgctgt gatcaatttt ggctcaaaag
    18601 aaaccattcg tgttcatttt agtccgaaca aacgtcaatt aaaattgttt gatggaggaa
    18661 aataatggaa aaccaaaatg aaagtttaat caaacagtat gttaagcgtc gtgcaaagcg
    18721 gcgcttattt ttgtgggtgt ttggtacttc tgcaggtttg attactatat tgatcactgt
    18781 gtttgtgacc ctttttctaa tacttgcggc aggttctatt gataattctg attcaagtag
    18841 tggtggcgaa gcttttacag gagaatattc ggaaggctta cccatttata aagaaatcaa
    18901 aggaagaggc cctttttctg atgagattgc gcaatatgct gtaggtgcag cagtgaagta
    18961 taaattatta ccaagtgtga tcctttcgca atacggttat gaatcagcgt ttggtacgtc
    19021 ggcgtccgca agaaatgatc tcaattattt tgggattacg tggtttgatg ggtgtctgtt
    19081 tcctaaagga actgcgcgtg gaattggtgg cattgaaggt ggctggtaca tgaagtttcc
    19141 caactcaaaa gctgccttct cctattacgg ctttatggta gccacacaat caaattttaa
    19201 tgcttgtgtc ggaaataaaa gccctggcgc aagcttattg atcttaggac gaggagggta
    19261 tgccgccgca ggaattactg aagacagtgc ctattataaa aattgtatgt ctattattaa
    19321 tacaaataaa ttgatggagt acgatgagtt tgcgattaaa cactggagag aaggcggcgg
    19381 aactggtggt acgattacag gaagctgggg caatccattc ccaggaagta gcttagataa
    19441 aaattcgttc agtggaggac aactttttgg gaaaaatcca ggaggagaat tccgacctaa
    19501 cgggttccat gatggactag actttggttc agtcgatcat ccaggaagtg agattcatgc
    19561 ggttcatggc ggaaaagtcg tgtacgttgg caatcctggt atttcaggtt tgggtgcgtg
    19621 tgtgatcgtg attaattacg atggcttgaa tatggtgtat caagaatttg caaatagtac
    19681 aggaaattct cgagtgaaag taggcgatca agtgaaagtt ggtcaagtaa ttgggatacg
    19741 agatacagca cacttgcatt taggatttac tcgaatggat tggcgtcaag cacaaggaca
    19801 tgcattcatt gatgatggta catggatcga tccgttacca tttttgaata gcagcaaaaa
    19861 atagatcagg agaaaaaata tggaaaataa aaccttaaaa atcgtcttaa cagctgcaat
    19921 tagcgttagt ttaatcggca atattgcgtt gttttggcag cttaaagaag aacaagagac
    19981 aaatacctat aaaattgaag aagtggctaa aaacgcgtct gataagctca aaaaaaattc
    20041 ttctgaggca caggcgaaga tcgacaagtt aaatcaaacc atcaatgaga aaaaccaaga
    20101 aatcgatcag ctgaagcaac aagatggcac aaaagcaaaa gaggaagtaa ctgaagcaca
    20161 aagaaagacg gcagaagagt tcggtcaatt ggccattgat aaatcattaa gcagaaatga
    20221 attaacggaa aaactaaaag atgtcgcaac ccaagaagtg atcgacaaat taagtcctgc
    20281 agacgatgat caccaacatg acgactacgg aagttactct tttacattag gtgacgtgca
    20341 aacttacgct caaacaagca gtgtaaaaga ggaacaaaat tttgtcgtat ttgttgatta
    20401 tacaatcggc aatcctcaat ttaaagatgt caaaccacaa aaaataaaag gtggattaac
    20461 tgtcactgaa aaacaagtag atggtcaatg gaaagtcaca gactttagtt atttcactcg
    20521 ttaggaggaa gaaaatgagt aagaaaaaag gagcaagaca acgttttaaa aaacgaaaaa
    20581 gttatcttag atggctgggg atctttatga ttctcggctt tttgattctt gctagtccga
    20641 tttacacaca taaaaaggta gacataccag atgaagtaag cacgaacgca tttttaaaca
    20701 cgaaggaact gacgatggtt tcaaaagaaa aaggagcgaa ccagcaatta gtttttgaat
    20761 ttgcgatcga cgatgaagat cagagcttat taaaagaact agctaatctt aattatcgtg
    20821 tagaagtaaa gacagctaaa ggggattatc aagcaataaa agccaaagtg atcaaggtgt
    20881 ctgatgatta ttttgtagtg aagttagcac atgtaccaga agaatatatc gccatgcgtt
    20941 taaccattat tcctgaaaaa attgatccaa aagtggatat gcaagaacca caagatctga
    21001 tttattacgt tcacgaagat aaggttaaag atcaagtgaa agatgaagat tatgaacaac
    21061 atgcgatcaa ttacaaagtg aaaggataca aaaaagaaca aaaagcagca caaaaacaaa
    21121 tggaatcctt ccaagcaacc attgatttga atgaagaatt agtgaagaag ctaaaagatc
    21181 aattgcctta tcaagtcgca gatgatcagg aaaatactga aaacaagatt aatagctacc
    21241 agcaagaaat tgaaacatcg aaaacgcaaa tgaaagatca agaagagatc attcaaaaac
    21301 ttcaagaaaa aattgatcgt atgacaaaag aaaagattta gaaggacagg tggagtgaaa
    21361 aaatgaagcg aacaaacttg gctgacaaag atactttcgc tgagcagaaa gtattgatta
    21421 aagcctatct caaagttgta aaagctaaag aaatatgtcg agaagtgaat ttatctaata
    21481 caacaatatc tgagttgaag aatggtcgaa agaatttaga tactttaaaa ttcagatcat
    21541 ttgaagctct atatgtagct gctaaaaaat attttacagc tgataacaaa taaaaaacag
    21601 gagtatttta tgtgaaaaaa gtatataaaa aatgcttatg aatcagctat atcaccttaa
    21661 ccatttgtta atgagatggg agaaaacatt aaccacgatt ctaacgcaaa catcaagcac
    21721 ataaaacatt taacactcct cctttctggc tgaagatttc aaccaaacag gaagacagcg
    21781 tatcaattat agcatacact ttttcttaaa ttcatttttc atatgacaaa atatttcctt
    21841 ctaatcgaca aagttagaag gattttttat tgtctaaata cacaaataac cttaatttat
    21901 aaagagcata aggaaacgtg ggaacacttt ttaaaaaaag tgttccaata ggctgtgcct
    21961 attacgtttc tcaaaaataa ttgtgggaac aaaatattta aaaataggat agtgaaagga
    22021 tagcaaagga tagtaaaagg atagaagcag gatagcgaaa aggataggct ccttttcgct
    22081 atccttttta aattggagga attaatatgg aagtaagaat aagaaatgta gatgagaaaa
    22141 tcgtaagaga aattgatcga agatgtgacg aactaagtaa ccgaacgggt aataaatgga
    22201 gtcgtaacga ttatttaaag ctactcgttg aaaatgattt tgatcgtcct ttgatggaat
    22261 ataaacaaga taaatttgat caattattaa atcagttaat agataaattt tcttttgttc
    22321 aaagtcataa tacaaaagta ttagaagaat atatttgtca gaataatcaa attatcgaac
    22381 ttttaattga acaaagtaga ggaggagaag tttaacatgg ccaaagttat agacaagcat
    22441 atttattttt atgaaacaca tatagatgtt ctagatgaaa ttattgcaac tcatgcagag
    22501 gttaaaaact atagtgaagc cgttcggttt ctatgtatga attatgattc agaagtggag
    22561 aaaaaagtaa attccaatca agcaaagttg aatgcaatgg gaaaagaaat ttctatttta
    22621 accgaaatgg tttcagagtt tgcggatctc catttgaaag atacagggat tttaattggt
    22681 acaaattcaa ctgtttacca agaagcaaaa gagcgtgtgg aaggcaagat aaaagcaaat
    22741 caaacgaaga aatattctcc taagataaag aaaacaataa gcgaatcagt gactacaaaa
    22801 agtgaagtat ttgatccaac aaggttctta aaacgataaa aattagaagg agaatgtgat
    22861 gagtaaatca cctgcagtca ttctcacttg tcaatttacc ttgcccaata aaaaatcttt
    22921 ttcaacatac attgattata tgacaagaga aaaagcgctg gaagaaaagg aacgacgtac
    22981 gcccgaggaa gaacaggaac tgcgtctaat caagaatgct ttagaggatt tttatattcc
    23041 tgaaggagaa actttttcgg agagtaagac gggtaaagaa ttcagcgaaa cgtcgaatga
    23101 agcgcaatcg ttgatgaaac atggaatcaa ttttgacaag ttagaagaac aagattttac
    23161 caaatatctt tcttatatga cacgtcacta tgcgttagaa caaaagaaag tactgacgca
    23221 tagtgaacaa aaagaatacc aacgcttgaa ccaagcaata aaaaaatatc aaacagagcc
    23281 acacaaaaaa gcttcaggaa atcttcctgg agttttttct atggcttcag acgaagtgaa
    23341 aggaagtgat ctgaaggaga tcaagcaaac cttccaaaga ggacaacaaa aaggctcaat
    23401 catttatcaa gatgttgtct ctcatgatca ttcgtatctt gaaaaaatag gattgtacga
    23461 tcccaaaaca gatactttag atgaagaagg tttaaaagca gctggaagaa aaatgatgga
    23521 gacattgttc gagaaagagc aactgaatga aacaggctac tggatggcaa cgattcaccg
    23581 aaataccaaa catatccata ttcattttgc agttgttgaa aaaaaaaata cgcgtaaacc
    23641 atacactgag attgaaaatg gtgtgagtta tatcgtaccg aaagggaaga gaaggcaagc
    23701 aacattagac gaaatgaaga ctaattatgt acatgagtta gaacgttttt cttatgaaaa
    23761 aaatcgaatg ggtatggaga aacgaaattt attgacacgg aaaagtgatt tgcgtaacac
    23821 cttaaccaaa gtagtgaaag agccagtacg ttatgatcga cacgcaatga gcttattaac
    23881 tgaagtatat aaaaacttac ctaaaaagcg ttcggaatgg cattacgggg atgaaaatcg
    23941 aaccaaactt tcaccataca caagagagaa actcgatgag ttaacccaat atgtgttaac
    24001 aaaagaacct ggatatcaag aatatataca gatttcaaaa gcattgaaag aagaagcaaa
    24061 aagtctttat ggggaaagca agagagaatc aaaggatgca gaaaaaaatg ctctctttga
    24121 tttaaaaaag cgcacaggaa atgccattct aacagaactg aagaaacagg atagtcaaat
    24181 aaaaccttta atagaaagga tggatcagat gcaatctatt tacaatgaac gatcctttcg
    24241 aacacttaaa cagttgccaa cgaatgaata caaatatagt tacgaagaat tcatgaagcg
    24301 caggaaacaa ttccaacaaa gagttgtcac gcaacggagt ttgcgtcaat taaatcgaac
    24361 gattaatgcc catgaagaaa aataccacgc aagtaaagca tacgaagagc aacaacgaag
    24421 aattcaaatg gaacaagaaa gacagtagga ggaatagcaa tgaaacaata tttagatcaa
    24481 tggaaagtta tagaaggatc attaagagaa gaacgaatcg aacaacttcc cgattgttta
    24541 gaaaaagagc atttgtttca gataagagaa atgttgataa acgaacagtt tgatccaaat
    24601 caatttttag tcgttgagta cccagctact ggtgtgtact gttgtaatca tgtgaagggt
    24661 gaaaaatatt ttatcattca agaatatgag ggcaagttag cgccttatta tactacttgg
    24721 gaaatgaatg aagaggggat caataacttc ccgtgtaaaa gcattgaaga gtctatttca
    24781 ctcacagaat gttagttgtt aagtgaataa aagaagtaaa agagtcctga acgtgattgt
    24841 ccaggactct tttttttcac tgaattgttt tccgccaatt cattgagtgg tgcgatttcc
    24901 gtctacatta tatcaaaaga aaggaggaag aagaaatggc ttattcaacg attggagttg
    24961 ttgttgaaaa aagcagagac aatcttgttt ttgtgacaga aattcaaaca ggcagagctt
    25021 ttgtagtcac agacaaagcg gcaaaagcat atcaaagtgg cgatatttta acgttaaatc
    25081 tgactacgaa gacgttcgtc gatgcggcag aagattatcc attt
//
LOCUS       DAZUJR010000040        24257 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.040, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000040 DAZUJR010000000
VERSION     DAZUJR010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24257
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.040"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            138..995
                     /locus_tag="ACG804_001513"
     CDS             138..995
                     /locus_tag="ACG804_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HFS4832449.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            1110..2030
                     /gene="pstC"
                     /locus_tag="ACG804_001514"
     CDS             1110..2030
                     /gene="pstC"
                     /locus_tag="ACG804_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HFS4832450.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            2030..2914
                     /gene="pstA"
                     /locus_tag="ACG804_001515"
     CDS             2030..2914
                     /gene="pstA"
                     /locus_tag="ACG804_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HFS4832451.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            2929..3735
                     /gene="pstB"
                     /locus_tag="ACG804_001516"
     CDS             2929..3735
                     /gene="pstB"
                     /locus_tag="ACG804_001516"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFS4832452.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            3751..4509
                     /gene="pstB"
                     /locus_tag="ACG804_001517"
     CDS             3751..4509
                     /gene="pstB"
                     /locus_tag="ACG804_001517"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFS4832453.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGINLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            4522..5199
                     /gene="phoU"
                     /locus_tag="ACG804_001518"
     CDS             4522..5199
                     /gene="phoU"
                     /locus_tag="ACG804_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HFS4832454.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            5437..5736
                     /locus_tag="ACG804_001519"
     CDS             5437..5736
                     /locus_tag="ACG804_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832455.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGRLMNTDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKK"
     gene            5777..6469
                     /locus_tag="ACG804_001520"
     CDS             5777..6469
                     /locus_tag="ACG804_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HFS4832456.1"
                     /translation="MLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLLNISIL
                     FVVIGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYL
                     TRPYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVI
                     GSMTNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPIS
                     VLFFLTVRRLKR"
     gene            6466..7233
                     /locus_tag="ACG804_001521"
     CDS             6466..7233
                     /locus_tag="ACG804_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HFS4832457.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            7333..8901
                     /gene="liaX"
                     /locus_tag="ACG804_001522"
     CDS             7333..8901
                     /gene="liaX"
                     /locus_tag="ACG804_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HFS4832458.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEITQVQL
                     STTTGSIYLKDTDK"
     gene            9198..9518
                     /locus_tag="ACG804_001523"
     CDS             9198..9518
                     /locus_tag="ACG804_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0080135 - regulation of cellular response
                     to stress [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HFS4832459.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            9518..9868
                     /locus_tag="ACG804_001524"
     CDS             9518..9868
                     /locus_tag="ACG804_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HFS4832460.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            10035..10973
                     /gene="hprK"
                     /locus_tag="ACG804_001525"
     CDS             10035..10973
                     /gene="hprK"
                     /locus_tag="ACG804_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HFS4832461.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            10988..11818
                     /gene="lgt"
                     /locus_tag="ACG804_001526"
     CDS             10988..11818
                     /gene="lgt"
                     /locus_tag="ACG804_001526"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HFS4832462.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            11862..12887
                     /locus_tag="ACG804_001527"
     CDS             11862..12887
                     /locus_tag="ACG804_001527"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFS4832463.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQIMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            12902..13840
                     /gene="galU"
                     /locus_tag="ACG804_001528"
     CDS             12902..13840
                     /gene="galU"
                     /locus_tag="ACG804_001528"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFS4832464.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKKLEAEGSKIDHNPKGITEIKEEKKK"
     gene            13965..14405
                     /locus_tag="ACG804_001529"
     CDS             13965..14405
                     /locus_tag="ACG804_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HFS4832465.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            14408..15010
                     /locus_tag="ACG804_001530"
     CDS             14408..15010
                     /locus_tag="ACG804_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HFS4832466.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDTKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(15078..16184)
                     /locus_tag="ACG804_001531"
     CDS             complement(15078..16184)
                     /locus_tag="ACG804_001531"
                     /EC_number="3.4.11.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HFS4832467.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLASIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            16394..17395
                     /gene="ccpA"
                     /locus_tag="ACG804_001532"
     CDS             16394..17395
                     /gene="ccpA"
                     /locus_tag="ACG804_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HFS4832468.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(17731..20076)
                     /locus_tag="ACG804_001533"
     CDS             complement(17731..20076)
                     /locus_tag="ACG804_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HFS4832469.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            20355..21257
                     /locus_tag="ACG804_001534"
     CDS             20355..21257
                     /locus_tag="ACG804_001534"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HFS4832470.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQIFDPEVFPELLAEEVIL"
     gene            21470..23245
                     /locus_tag="ACG804_001535"
     CDS             21470..23245
                     /locus_tag="ACG804_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HFS4832471.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSFYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYSSSKKMLPWFLGLAVSFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEAKKLKERPFLLSKQEWLKLSLFLLPLVGFSIVYQWIEYKNETTYSIAAIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALDASPTFHAVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYQKGT
                     IKKKKEFYLMGSGDGKTMNDLPIVFAFLKSGYAYAWRYKDFHQGGNYSFGTQEQVEQA
                     QELLNLPLMDNWIDSSDPRTPDFQLTKTAKVANVMIKIYQVLAIPVLIASIAGILLMI
                     LGTAFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            23502..>24257
                     /locus_tag="ACG804_001536"
     CDS             23502..>24257
                     /locus_tag="ACG804_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFS4832472.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEENTLCSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFLNRLTPYALILIRLFPHPDFVLASTRTKIKNKLINETRKKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQK"
BASE COUNT         7748 a         4334 c         5089 g         7086 t
ORIGIN      
        1 tagcatagaa acttttaatg agatagtttt ttttacaatt atgagaattt attttgttat
       61 ttaatgattt tgattcgttt tcatcaagta atgaaaatga taaaataaac atactttagg
      121 attaaaggag atttctaatg aaaaaactta aattattctt accaataata ggattagcca
      181 ttcttttatc aggctgttca aagtggattg atcgaggaga atccattacg gctgttggct
      241 cttctgcttt acagccttta gtagaaacag ttgctgaaac ttaccagaca gaaaatcctg
      301 gaaaattcat caatgtacaa gggggcggaa gcggaactgg tttgtctcaa gtacagtcag
      361 gagcagtcga catcggaaac tctgatttgt ttgcggaaga aaaatcgggg atcgatgcct
      421 cagcattagt cgatcatcga gtagcagttg ttgggatcac tcctattgtg aacaaggata
      481 ttggcgtaaa agacatcagt atggaaaacc tgaaaaaact atttacaggc gagatcaaaa
      541 actggagtga agtcggtgga aaagatcagc cagtagttat attgaaccgc gcttcaggaa
      601 gcggaacccg tagcacgttt gaaaaatggg tattggacgg agaaacagct gttcaggcac
      661 aagaacaaga ttcaagcgga atggtgcgcc agatcgttgc cgacacaccc ggtgcaatca
      721 gctatgttgc tttttcttat gtttccgatg atgtagatac gttgaatgtt aacggtgtag
      781 aaccgacaga tgaaaatgtg acaacgaaca aatggacgat ttgggcatat gagcatatgt
      841 acacaagaga tcatccaaaa aaactgacaa aagaattttt agactatatc ttatctgatg
      901 aagtacaaga taacatcgtt ggagaactag gttatatccc tgtttctcat atgaaagtcg
      961 aacgtgattg gcaaggaaat atcgttaaag agtaatcttt acacaaaatt tacaaactta
     1021 gctaaacttt tacatgttat taaaaccaaa ttgatgttca atttgtacac tgagtgagta
     1081 tgttaaacct gattaagggg gagtcatctg tggaagatgt gaaaaaagta ttattaacaa
     1141 aatcaaaacg ttcaaaaatg gaacagcgtg gaaaattcat cagtttttta tgtatcgcgc
     1201 tgatcgtgtt ggttgtatta tctatttttt attttgtagc tagtaaagga ttggccacct
     1261 tttttactga taagatcaat gtatttgatt ttctgtttgg tacagattgg aatccaagcc
     1321 aaatcggagc aaatgggaaa ccaatggtag gggcattgcc tatgatcaca ggttcgttta
     1381 ttgtgacctt tttatctgct atcgttgcca cgccatttgc cattggtgca gcagtattca
     1441 tgacggagat ctctcctaaa aacggaacga agatcttaca gccggtcatc gagctgcttg
     1501 taggtattcc ttctgtcgtt tatggtttta tcggtttatc agttatcgtg ccttttgtca
     1561 gaagtatttt tggcgggaca gggtttggta tcttagctgg tacatttgtg ttgttcgtta
     1621 tgatcttgcc gactgtcaca acgatgactg ttgatgcatt aaaggcagtg ccacggcact
     1681 atcgggaagc ttcattagcg cttggtgcca caagatggca aacaatctac aaagtcgtgc
     1741 tacgagcagc cgtgcccggg attttaacag cagtcgtttt tggtatggct cgtgcgtttg
     1801 gtgaagcctt agctatccaa atggtcatcg gtaatgcagc attgatgcca acaggactta
     1861 ctactcctgc ttctacattg acgtccatct taacaatggg aatcggaaat acaatcatgg
     1921 gaacagttga aaataatgtg ttatggtcat tagcgctgat cttgctattg atgtcattat
     1981 tctttaatat cgtgatccgt atgattggga agaaaggaga gctgaaataa tgaacgcaaa
     2041 acgctcagat aaaattgcta caggtgtttt atatatagtt tcggggatca tcgtattgat
     2101 tttagcagct ttactacttt atatcttagt tcggggaata ccgcatattt catggtcctt
     2161 cttgaccgaa ccttccaaag cctaccaaga aggcggtgga atcgggatcc agctatttaa
     2221 ctcgatttat ttgcttttga tcacgatgat catcagtttt cctatttctt taggtgcggg
     2281 tatctatctt tcagaatatg ctggaaaaaa ctggctaaca gatgtgattc gcacgtcgat
     2341 tgaaatcttg agctcgttgc cttctgtcgt tgtcggttta ttcggtttct tggttttcgt
     2401 tattcaattc cagtatggtt tctcgattat ttctggtgca ttggctttga ctgtattcaa
     2461 cttgcctctt ttgactagaa cagttgagga gtctttacaa gcggtccatt acacacaacg
     2521 agaagcagga ttggccttag gtttgtcacg ctgggaaaca gtgataaaag tggtggttcc
     2581 agaagcgaca ccagggattt tgactggtgt gatcctaagt tctggaagaa tttttggtga
     2641 agcagctgca ttgatctata cggctggaca aagtgcacct gcgttagatt ttacgaactg
     2701 gaatccatta agtgtttcaa gcccgatcag cattttccgt caagctgaaa cattagctgt
     2761 ccatatttgg aagatcaata cagaaggcac gatgcctgat ggtgtttctg tttcggctgg
     2821 cgcttctgcc gtgttgatca ttgctgtttt actgttcaac ttcggcgctc gtgcgattgg
     2881 caaacgatta taccgaaaaa tgacttcagc ctaaggagaa gaagcaaaat gaaaaaatat
     2941 aactggaatg aaacaaatgt catcaccatg ccaaaagaga aagaagtagc actatatacg
     3001 gatgatctac atgtctggta tggcgacaat gaagcaatca aaggagtgga tctggaattt
     3061 gaaaaaaata agatcactgc actgattggt ccttccggct gcggaaaatc tacgtatctt
     3121 cgttcgttga atcgaatgaa tgatgggatc gctaatacga aaatcactgg gaaaatcatg
     3181 tatcaaggcg tagatattaa tgcgcctcaa gtggatgttt atgagatgcg caaacggatt
     3241 ggcatggttt ttcaacgtcc taatccgttc agcaagtcga tttatgacaa tattacattt
     3301 gctttgaaac agcacggcga aaaaaacaaa aagaaattag atgaaatcgt tgaaacaagc
     3361 ttgaaacaag ctgccttgtg ggaccaagta aaagacagct tggacaaaag tgccttggct
     3421 ttatctggcg ggcaacagca acgtttatgt attgctcgtg cgatcgcgat gaaacctgat
     3481 atcttgctgc tagacgagcc ggcaagtgct ttggacccta tttcgacagg aacggttgaa
     3541 gaaacacttg taaacttgaa agaagactat acgatcatca tcgtgacgca taacatgcaa
     3601 caagcagctc gtatcagcga ctatactgcc tttttctatc taggaaaagt aatggaatat
     3661 gacaaaacta acaagatatt taccagacca aaaattcagg caaccgaaga ttatgtgtcc
     3721 ggtcattttg gttaagacgg aggcctcaac atgacaaaag aaattatttc atctaaagat
     3781 cttcatctgt attatggaaa gaaagaagca ctaaaaggga tcaatctaag tttcaatcaa
     3841 ggggaaatca ctgcgatgat cggtccttct ggttgcggga aatccactta tctgcgttct
     3901 ttgaaccgga tgaatgacct gattccgaat gtaacgatca ccggaagtgt tttatataaa
     3961 gacaaagaca tctatggtcc aaaaacagat gttgttgaac taagaaaaga aatcggcatg
     4021 gtattccagc agccaaaccc atttcctttt tctatctatg aaaatgtcat ctatggattg
     4081 aaattaaaag gggaaaaaga taaaaaagtc cttgatcaag tagttgaaga aagcctgaag
     4141 gcagcgtctg tttgggatga tgtgaaagac aaattgcata aaagtgcttt atctttatcc
     4201 ggtgggcagc agcagcgtgt atgtatcgca cgtgttttgg cagttaatcc ggaaatcatc
     4261 ttattggatg aaccaacaag tgcgcttgat cctgtttcta ctgggaaaat cgaaagtatg
     4321 ctgttagaat taagagagcg gtatacgatg atcatcgtga cccataatat gtctcaagct
     4381 tcacgtattt cagataagac ggcattcttt ttagatggtc acttgatcga atacaacgat
     4441 acgaagaaga tattcatgaa tccagaaaaa caagagacag aagattatat ttcaggtcga
     4501 tttggataag gaggaaacgg aatgctacgt acacaatttg aagaagaatt gctgaatctc
     4561 cataatcagt tctacgaaat ggggatgatg gtgagcagcg ccgtgcacaa gtcagttcgt
     4621 gcatacatca aacacgataa aatcttagcc caagaagtta tcgaaaacga tataaatatc
     4681 aataacatgg aaacacgctt ggagaagaaa agttttgaaa tgatcgcatt gcaacagcca
     4741 gttacaactg atttgcgtat gatcattacg gtcatgaaag ctagctcgga tttagaacgt
     4801 atggccgatc atgcggtgtc tgttgctaaa tccacgattc gcgtaaaagg gcagacgaga
     4861 ataccggaaa tcgaaaaaga gatctccgat atgtccgatt atgtgaaaaa aatggtggac
     4921 aacgtcctag ttgcttatgt caaaacagac gaaaaagacg cacgtacgat cgccaatatg
     4981 gatcaaagag tcaatgacta tttcaatcga atctataatg caacaatcaa aaatatgcag
     5041 gaaaatcctg agacagtcat cagtggaaca gactacttga atgttgccag ttatctagaa
     5101 cggatcggag actatgtgac aaacatctgt gaatggatcg tctacttggc tacagggaaa
     5161 atcactgagt taaatacgaa ccacaatgag attttctaaa ctgaagctgt gattatgccg
     5221 tttgtttagg aaaagaggtt gtgaaatcag cggttgtgaa aaagctgttc tgcatcaagt
     5281 aataagaaca gtcaaacaaa aaatagctcc tcatattttt cgtttggctg gacttattac
     5341 cgcagatgca agcttttgaa caccgtttat tcgggaaagg gtttgtgaca aaacatgtca
     5401 caaacccttt tcatcatttc atagaaagga taaagaatgc aaaaaaaaat tagcatcatc
     5461 actatatttt ttatttgtgt gcttacttca tgggttattc agcatcaagc tgctttatat
     5521 gaagtacctg tcatcgagat cgaaaaagta cgaataaaag aggatcatca attgattaca
     5581 ggaagactga tgaacacgga tcaaaaagga gaatcgattt atttatcggt tccttatcaa
     5641 aaaaatcaaa tagaaacagc aaatataaaa gcgagacaaa tgtatctagt ccaaatgcat
     5701 ggagatgaat ggcagctagt agcaaaaaaa aaatgatggc tggcttttct tcttcacaag
     5761 tatctccatt ggcgccatgt tgcttattgg cggaaaacag ggtctatttg ctttaggaag
     5821 tctcatcatc aatatcgttt tacttttact tttgttgctc atctttacta aaacagaagg
     5881 gatttctcta ttaaatatat ctatcctgtt cgtcgttata gggatgatta ttagcatatt
     5941 ggctttagat ggatggaata gaagcagtat aatcaaaatt tcagctgcag ttacgagtgt
     6001 ttttttagca ttttttattt gtcttttgac aatgaatcat tggaaagacc aaggactgcg
     6061 ctatgaggaa ctgaattatc tgacacgacc gtatcgttct gtttttcttt ctagcgtact
     6121 gattggaaca gctggaggaa cactcgatac cgttatcaca gtcattgcga cattagaaga
     6181 attgactaag cgacaaccag aaataacagc gaaacagtta tggctttcag gaaggcaagt
     6241 gggtcgagat gtgattggct cgatgaccaa tatccttttg ttcgtctata tcagtgggtc
     6301 agttccatcg cttcttttat atttaggaaa tcaatggtcg ttcaaagaaa cgatagaaca
     6361 gcatttatca ttggaatttt tacgcgtcat tgctggcagc ttaggaatag tattatcgat
     6421 ccctatctcg gtcctctttt ttctgactgt aaggaggctg aaacgatgaa tgtacttatt
     6481 atacttgttg ggattttagc aatcagcgtg ctacttattg gcggtacgca aggtatgtat
     6541 attcttttag gcttattcat caatttaggg atctttttcc tgttgttatt cggttatcat
     6601 cagaagtggc cgatactggc attgtcggtc ataggatttt tattgattgc tgtggttatc
     6661 ttatttttta tcaacggtta taatctaaaa atgcgtgcag cttttgtgag tatactgatc
     6721 tttttatttt gtttcctact attgcttcct atcactgatt ttttagcgat ccaaggtttt
     6781 acatcggtag aactagaaga attatctggc ttagataaga ctttagcgat tgattttaga
     6841 ttacttacga gatcgttgct tctgattagt cttagtggtg ctgttttaga tgctagtgta
     6901 gcaatttcta gtgggacatt cgaagtatat caggcaaatc cgcaattatc tttttaccaa
     6961 ttgcgccatt ctagtttcgc tattgctaaa aaaatattgg cgtcaacagt aatgacactt
     7021 ctttttgcat tcatgggaag ttctttagcg ttgatcctct ggtttattga tttagacatt
     7081 ccttttcagc aagtgatcaa tgaaaaatca tttgttctag aatatacgat ggctattctt
     7141 accacattgt ctgcactact tgttcttcct ttaacctgcg tgactacagc atatctcttt
     7201 acaaaaaaga aagaacaact caagatggag taaaagttac aacttaagtc ctatgacatt
     7261 tttactgaat cagtgcataa tatggatgta aggaaaagct tgcaaacaat tttgcttaag
     7321 gaggcaattt ccatgaaaga aagagaacgt attttagatt tagtgaaaaa aggaatcctt
     7381 tcgactgaag aaggcttaga tttattagaa agcatggcaa ctgaaaaaga cgaaaagcaa
     7441 ataaaaaaag aagcagacaa ggtaactgct agtcataaag aaaaagatca ggcaagtcaa
     7501 ttgatcgata aacttgaaaa cggcgaagaa gaaatttctg agccagttga tccaaaggaa
     7561 agagaaaggc aagatcaaga aaacttagaa aagatcttag atgaactagc aactgaagcg
     7621 aataaaactt cggcgcgtct agatgaagta aatgctcaat tcgctgacaa taaggcagca
     7681 cgcaatgaga aacaggaagc attgatgcag ctgaatacaa aagaagaatt aggcgagttg
     7741 acagaagaag aattagcaca gcgtcagacg ttagaagcag aaatcaaaga attagaagct
     7801 agtggcgata cactgttaga agaacaattg aaattagaag cagaattaaa agatatccgt
     7861 aagaatcaat ggtctgagaa aaaagaaacg tttactgata agtttgaatt gccagatgat
     7921 tggaaagatc aagcaacaga tacactgaat caagtaggcg aaaaaatgtc agaagctgga
     7981 tcacagttag gcaaattctt gaagaaaaca ttccaaactg tttcagaaac agtgaatgac
     8041 aacatggaat ggaaagatgt cagcttacgt gtccctggga ttgcgacaac gaaatttgag
     8101 catgaatttt actatgaagc tcctgcagca agtatccttg atatcaaggc agcaaacgga
     8161 aacgtgacgt taaaaacgtg ggacagcaac gatgtgaaag ttgaagctaa gatcaaactt
     8221 tacggaaaaa tgggtgctga accatttgaa gcattctctg aacggagcca gattgaggtt
     8281 aatgaagatc atatctcctt ccaaattcca aataaacgtg tgcgtgcaga ccttgttttc
     8341 tacttaccta aacgagtata cgaccacgca gctattaaac ttctaaatgg caacatcatg
     8401 attgaaacat tggaagctaa agatatttat acaaaatcta cgaatggtaa catcatcgtg
     8461 gaccaattaa ctgcaacgat gctggaagta gaaggtgtaa acggcaatat cgatattcga
     8521 aacgggaaca tcttagattc tattatcgaa acagtaaatg gtacagtgac atttggtgcg
     8581 acagcagaaa acctttctgt gtctttggta aatggtgatg tacgtcttac gattaaagaa
     8641 gataatttga aaaaagtaga agcaagttca gtgaacggaa atgtcaaagt cgctttacca
     8701 gatggcatcg gtttggaagg acatgctaaa acaagtcttg gaagtatcaa cagccgtctg
     8761 tccaattacg aagtagttcg tgagaaaaaa gaacggacaa accaaatgtt gcaattccgt
     8821 cgtgtttcag atggtgaaat cacgcaagtg caactttcaa cgacaacagg aagtatctat
     8881 ttaaaagata cagataaata aagaggttgt gaaagagatg ttcagccttg agcaataaga
     8941 agcgattttg taaaatagct tcccctattt tacaaaattg tgccttattg ccgataggct
     9001 atctcttgaa caccgtttac caagagatta tgaacctgcc aattatcgcc gagtcacaag
     9061 gaataatttc agaaaaagct cgtcacgttt tatgaatatg gtaatttgtg accgagaatt
     9121 ttgcagaaag acaccgatta agaagaaggt tgtcacaacg attttcttca tttaaaatag
     9181 tagaacagag gtgagacatg atgaaaaaaa agttgacaaa atccaataaa aatgttgttt
     9241 tgacagggac tttagcagga ataggagaat acatcgggat tgatccgact gttatccgtg
     9301 tgctttatgt attcctgagc ttagttgctt ttggaagtcc aatcatttta tacattttat
     9361 tagctttgat tatcccatct gcgcgttctg cacgaacaaa ctatggacat aacaatgcat
     9421 attatgaaaa aaacaattat cgtgaacaaa ctcgtgaaca aacaaaaaaa cgcaaagaag
     9481 cggaaaaaat cgatgatgac gaatggagtg acttttaatg tcgtactttc aacgtatttt
     9541 agttaatacg ttaacattca tatcattggc tgttcttttt cctgcgatgg tccatgtgag
     9601 cagtatttgg acggccgttc ttgccagctt cgtattgtct gtgttgaata tgtttgtcaa
     9661 accgattttg acgatactgt ccctgccctt tacattagtc acattgggat tgtttacgtt
     9721 tgttatcaat gcagcgattc ttaaaatgac ctcctttttt gtgggagcag aacattttag
     9781 tttttcttca ttcggtgcag cgttgttagt agctatcttg atgtcgcttg tcaatgtaat
     9841 tgtcagtgaa cataacagta gaaaataaaa gaaagctgtg ccgaactatc ggcgcagttt
     9901 ttttatttag aatcaggaat gcgttttcta ttacattggt aattaaataa aaacgttttt
     9961 tttaattggt agtacttttg gctagacaat gataaaatga tagagaacac tctaatagaa
    10021 atgaggtagc atgaatgtca gaagttgtaa aagttagcca attagtgaaa aaattatctt
    10081 tggaaatcgt gacaggcgac gagaaaagct tagaccgtgt catcgtaact ggggacatct
    10141 cacgcccagg actagagttg actggttatt ttaattatta ttcccataat cgtttacagc
    10201 tatttggcag taaagaaatc agttttgcgg aacggatgat cccagaagag cgtttgatca
    10261 tcatgagaag attatgtagt gaagatatgc ccgcatttat tatttcaaga ggattaccgg
    10321 ctccagaaga aatgatccag gcagcaaatg aaaatgggat agctgtactg cgttctccca
    10381 tctcaacttc tcgtttatta ggagaattat ccagttattt agatggtcgc cttgcccctc
    10441 gaacaagtgt ccacggtgtt ttagtggatg tttacggatt aggtgtactg attcaaggtg
    10501 acagtgggat aggaaaaagt gaaacagcgt tggagttgat caaacgcggt catcgattga
    10561 tcgcagacga tcgagtagat gtttatcagc aagatgaatt aacggtgatc ggagaaccgc
    10621 ctaaaatcct ggaacatcta attgaaatcc gaggaatcgg gatcattgat gtaatgaatc
    10681 tttttggtgc gagtgcggta cgtggctcta tgcaagtcca gttggctgtt tatctggaag
    10741 catgggcaaa agataagaaa tacgaccgtc tgggctctga agacacgacc gttgaaatcg
    10801 cggaagtggg cattccacaa ataaaaatcc ctgtcaaaac aggacgaaac gttgcaatca
    10861 tcattgaagt agccgcgatg aatttccgtg cacgtacaat gggctttgac gcaacgaaaa
    10921 catttgaaga aagattaagt cgcttgattg aagaaaactc aggcaacgac tagcaaggag
    10981 tgacaatatg ttagcacaaa tcaatcgagt tgcttttgag cttgtaggga ttcctatcta
    11041 ctggtatgca ttgatcatcg tatcaggtat cattatcgcc atgtggctta gcagcagaga
    11101 ggctgttcgg gtaggattaa aagcagatga tgtgacagat tttatgttgt ggggattgcc
    11161 tatctccatt attggtgctc gcttatatta tgttttattt gatcttcccc agtatatagc
    11221 tgatccaatc caaatattca atatccgttc aggaggctta gctatttatg gcggactgat
    11281 tgcaggcgcg atcacgctgt atttttttac taaatatcat tttatttctt tgtggacttt
    11341 tttagatatc gctgcaccaa gtgtattatt agcacaggca atcggtcgtt ggggaaattt
    11401 catgaaccac gaagcatatg gaccagacac gacgcgaagc ttcttagaaa gtctgcattt
    11461 accgcaattc atcattgata atatgtatat cgaagggatc tatcgtcaac caacatttct
    11521 ttatgaatca ctttggagtt tgattggatt tattttgctt ttgtttttac gaaagaaacc
    11581 acaccttttg aaaaaaggcg aagtcctttt atgttatcta atgtggtata gtttcgggcg
    11641 tttctttatt gaaggattac gtacagacag tctttacttt ttaggtgtga tccgtatttc
    11701 tcaattatta tctgctgtgt tatttgtcgg tacattgatt ctatttattt ggcgcagaaa
    11761 aaaaggaaat ttaccggatt atgaccgctc attaggaaaa aatcaacaaa ttatctgatt
    11821 tttagagcgt taaaaatgaa aaaaatttca ggagtggtaa aatgaattat agagtagcgg
    11881 ttttaggacc aggctcttgg ggtactgctt tggcacaagt cctcgccgaa aacggacatg
    11941 acgttcggat ttggggacat cgtgcttcac aagtagaaga aatcaacacc caacacacga
    12001 atcaacgtta tttaccagat cattatctac ccgattccat ccaagcattc accaatatgg
    12061 aagatgcagt aaaagacgca gatgcggtgc tattcgtcat tccaacgaaa gcaatacgtt
    12121 ctgttgcaaa agaactagtg cctaaattga atacaaagcc agtgatcatc catgcaagta
    12181 aaggattaga acagggaaca cataaaagga tctctgacat cttgttagag gaaatcccag
    12241 cagaaaaaag aaaagctgtt gttgttcttt ctggaccaag ccatgcagaa gaagtagcga
    12301 aacatgacat cactacgatc acagctgcaa gtacagatgc aaaagcagca aaatatgtac
    12361 aagagctgtt catgaataat tattttcgga tctataccaa tcctgatgtg atcggtgtag
    12421 agatgggggc agctttgaaa aatattattg ctattggtgc tggcgctatt cacggcttag
    12481 ggtttggcga taatgcaaag gcagcaatca tgacgcgcgg attagctgag atcagccgtt
    12541 taggtgtagc aatgggtgcc aacccgctga cctttatcgg attaagcgga gtaggcgatc
    12601 tagtcgttac ttgcacaagt gttcattcta ggaactggcg cgcaggcaac ttgttaggac
    12661 aagggcagcc cctagaagag gtgctagcca atatgggaat ggtcgttgaa ggtgtgaata
    12721 ctactcaagc agcgatggaa ctagcccaaa taatggaaat cgaaatgccc atcactcaaa
    12781 caatctatga agtgctgtat gaacaaaaag aaatcaaaac agccgcaaaa gaaatcatgt
    12841 tacgtgatgg gaaaaaagaa aatgaattct cattaacaat tttttgaagg agcgaatgta
    12901 tatgaaagtc aaaaaagcag ttattccagc ggcaggatta ggaacaagat ttttaccagc
    12961 aacaaaagct atggcaaagg aaatgttgcc aattgttgat aaaccaacaa tccagttcat
    13021 cgttgaagaa gcgttgaaat caggaatcga agacatcttg atcgttacag gaaaagctaa
    13081 acgaccaatc gaagatcact ttgattcaaa tattgaatta gaaacaaacc taagtgaaaa
    13141 aggaaagacc gaattattga aattagtaga agaaacgaca gatgtcaact tgcatttcat
    13201 ccgtcaatct catccaaagg gtttaggaca tgccgttctt caagcaagag cctttattgg
    13261 aaatgaaccg tttgtcgtta tgctaggcga tgatatcatg gaagatgaag taccattgac
    13321 acagcaatta atcgatgatt acgaacgtac tcatgcttct acgatcgccg ttatgcaagt
    13381 tcctcatgat gaaacttcaa aatacggaat tatcaatcca ggagaagtat tggaagatgg
    13441 gttatacaat gtcaaaaact ttgttgaaaa accagatcca agcaaagcac caagtgattt
    13501 agctattatt ggacgttact tattgactcc agaaattttt gatgtattgt ccgagcaaca
    13561 accaggagcc ggaaatgaaa tccaactaac tgacgcaatc gatacattga ataaaacaca
    13621 acgcgtattt gcccgtaaat tcacaggtaa acgttacgat gtcggtgaca aatttggttt
    13681 tatgaaaaca agtattgaat atggtctaac acatccagaa gtaggtgcac ctttacgtga
    13741 gtatatcctg tctttaggta aaaaattaga agcagaagga agcaagatcg atcataatcc
    13801 aaaaggaata acagaaatca aagaagaaaa gaaaaaataa cccttttttc taacgagctt
    13861 cagctgctaa ttgaataaaa agtagttgaa gctcgttttt atttgtttaa aaaacacgaa
    13921 aatgctatcc ttatagaaaa gagagacaag aagggagttt gatcatgtca ggaggagaaa
    13981 ttgcaggatt gatcgcagca atcgcctttg cgatacttgt cgtttttatc gttcgtgtgt
    14041 tgttgcaagt ttctaaaact ttagaaaaag tagatcagac tgtagcagaa gcaaatacga
    14101 cgatcgaaat cgtcacaaaa gacgtagatc ttttgtctag acaagtagaa ggcttgctgg
    14161 tcaaaagtaa tgaactgctc ttggatatca atggaaaagt cgcaacgatc gatccattgt
    14221 tcacagcagt tgctgattta agtgaaagtg tatcagaact taatcattct agtaaaaaca
    14281 tcgcgacgaa agtcggcgga atcggtaaaa cgacagctaa agcgacggtt gccggaaaag
    14341 tcggtgggac agcgatgaaa ttttttaaaa acaaaaaaca tactgaaacg acaggaggaa
    14401 aataaaaatg gctaaaaaag gtggattttt attaggtgca gtagtcggag gaacagccgc
    14461 agcaatcgcc gcgttattgt tagcaccaaa atctggtaaa gaacttcggg atgaattagc
    14521 tgcccaagcg gatgatttga tggatatggc ttcagattac acagatatgg cgaaagaaaa
    14581 atcgactgag ttaacaggta ttgcaaaaga aaaagcgcaa gatctttctc aacaagcagg
    14641 tgatctagca ggtagtgtca aacaaaaagt aagtgaatca gcagatgaag caggaagtga
    14701 atctgacgat atcttgttaa atcttaaaga acaatcagct gacttatcta atcgtttcaa
    14761 aaaaacggca gaagatatga aaaaacctgc agatgaatta ggaagtattg ctaaagatac
    14821 ttcagaagat atcatgattg atgtaaaaga cgctgctggt aaagcaggag atactgtcaa
    14881 tgaaggaatg tcagaagcaa aaccagttgc agatgacaca aaagaaatga tgaaaatggc
    14941 aaaagaagat gcgaaagaag ctaaaaaaga aataaaagat acaatgacag attcatctac
    15001 aaatcactaa aatcactaaa atcacaaatt tatagaataa aaaggtggga gcggactagc
    15061 tctcaccttt tttactctta tttttctaaa actagtaatt cttttggtgt agtcgtgaat
    15121 ggcacacagc catcgcttgt cacatataca cagtcttcga tacgtacccc tactttttca
    15181 ggaatataga ttcctggttc aagagagaag cacatccctt cttcgattac taagtcattt
    15241 ccttctacaa gggaagggaa ttcgtggacg gttgttccga tcccgtgacc taaacggtga
    15301 ttgaaatatt cgccgtagcc atagctgttg atcacgtttc gtgcgatttg atcaagttca
    15361 cctgctgtca cacctggacg gacggcttct tgtgcggcaa gctgtgcttc aagagtgatg
    15421 ttgtatattt tttcttggaa gtcggttggt ttttgataag caattgtacg agtagcatca
    15481 ctgcaatagc cattccaaac aacgccaaga tcgaataaca caagttcatt cggtgaaatc
    15541 ttcgtgtttc ctggtgtacc atgagggctt gcagcatttg ctcctgcaag gactaatgtg
    15601 tcgaaagaca tttgtgaaac accttgtttt ttcaattggt attcgatttc tgcaatgatc
    15661 gcttgttcag tcacgccttc tttcactgct ttaaagccaa tctcaaatgc aacatcggcc
    15721 catttaccag cttcgatcag tttgtctttt tcctctagag ttttgatcag ttgtagacgt
    15781 tggatgatgg aagctagatc agtgtaagaa tccgttcccg tcaagatatc agagatagca
    15841 tcgaagcgct cgacagtcaa ggcgttcttt tcaatcccta cattgccagg ctgaccatag
    15901 cgagcacgaa gttcttttcc gatgatctcc caagggtttt cgctgtctaa atagccacgg
    15961 acatcatacg cccaactact gttttgagca tcttcaactt ccaaagcagg agtgaaaagg
    16021 aaaggatctt gttcaagagg gataaaaaga gctagtacac gctcatgagg atcactttcg
    16081 tatccggaaa agtaagcgat gtggccaggg tcgctgatat aagccaattc gacttggtgt
    16141 tgtgccatcc attgacgtag ttcattgatt tttacgttat tcatttggca acctactttc
    16201 taaattaatt ttgtattcaa taattgtacc actgatttat taaaagacca acgttctaaa
    16261 aactgaaaaa agtaaaaatt ttcatgaaaa cagagataaa acggttgcaa ttcttgagat
    16321 tatttgatat tctattttag aaatgtaaga cgtattttca gaaaacatat aaaatatgaa
    16381 taggagaaca caaatggaaa agcaaacaat cactatctat gatgtagcga gagaggcaaa
    16441 tgtttcgatg gctactgttt cacgtgtcgt aaatggcaat ccaaacgtca aaccagcaac
    16501 aagaaaaaaa gtcttggaag ttatcgatcg cttggattat cgtccaaacg cagttgcgcg
    16561 tggcttggca agtaagaaaa caacaacagt tggggtaatc atccctgatg tcagcaatat
    16621 gttctttgct tctttagcac gtggtatcga tgatgtggca acaatgtaca aatacaatat
    16681 tatcttagca aattcagatg gtaacgacca aaaagaagtc aatgtattga ataacttact
    16741 ggctaagcaa gtggacggcg tgatcttcat gggtcaccat atcacagacg aaatccgtgg
    16801 agaattttca cgttcaaaaa ctcctgttgt attagctggc tctattgatc cagatgaaca
    16861 agtaggtagc gtaaacattg attatgtatc agcaacaaaa gatgcagtaa acaaattggc
    16921 aaaaagcggc aataaaaaaa tcgcttttgt cagtggtgcg ttgatcgatc ctatcaatgg
    16981 acaaaatcgt ctgaaaggct ataaagaagc attaagcgaa aataacctac catatagcga
    17041 aggattgatc tttgaagcac aatacaactt caaagatggt ctatctctag tcgatcggat
    17101 ccataatagc ggtgcaacag ctgtctatgt ttcagatgat gaattagcca tcggtatttt
    17161 ggatggttta ttagaccgtg gcgtgaaagt accggaagaa ttcgaaatca tcacaagtaa
    17221 caattcacta ctgacagaag tagctcgtcc tcgtttaaca agtatcacac aaccattata
    17281 cgatttaggg gcggtatcta tgcgcctatt gacgaaaatg atgaataaag aagaagtcga
    17341 agaaaaaacg attatcttgc cttatggaat cgaagaaaaa ggatctacaa aataataaaa
    17401 ggacaaccat tcagaggttg tgagcctgcc gtttaactct gcgttacaag gagcaatttc
    17461 aaaaaacagc atttcatgtt tgatgaatat tgtgactcgt gattcggagt tggcaggaga
    17521 acaccgttta ttcgggaaaa ggggttatga caaaattttg tttaatcctt tttttttgtc
    17581 ttaaaaaaga gagaaagtgg ttgaaattac atttatcgta tataaaacaa tccgtgtata
    17641 gatgctgcat tatgttcacc accatcaaaa aaataaggga ctgtgacaat actattgtca
    17701 cagtccctta ttactgtgta ttctattaaa tcaatcatct ttctcatctg attctttggt
    17761 tgcttgattc gctcttgcat aagctgaagc ggtgttccag taatctgtat agttttcatc
    17821 ggtaccgcca acgccaaatt taaaggcgct tttcttcggt ccatttttcg cccatagcga
    17881 ttcaactgtt tttcctggtg tttggatgga ttttttattg acagtaactt ttccaggtgt
    17941 ttgaccagta aatccagata cttttttctt catcacatca gatgataatt cgaatttctc
    18001 atcagtgcca aaaatgtcag gttttgcttg gtaagcttga ttgatcagat tggcaagata
    18061 attagccgaa cgtatccttg ctttgctgtc cattccagta ttgtcatcgt gccctgccca
    18121 gctactgatg gtaatagacg gagtagagac aattagccat gaatctcggt attcattggt
    18181 agaaccagtt tttccgaccc aatctgcttt tcctagattt ccgtttaagc ttgagatggc
    18241 atctttgaat ggtgtagtga tttttgcatt gatcacactg cgcatcatgt cattcatgat
    18301 cgatgccgtt gcttccgaat agatccggac agagttgctt tcgtgtttat aaattacatt
    18361 tcctgcgtta tctgtgatgg aatcgatgat atagccttct tcatagacgc cgccgtttgc
    18421 taaagcctga aatccattgg tctgttgaag cgtcgtgaca tctactgtac ctaaaggagc
    18481 agattcaacg ccccaattgt catttgccgg gtagttcatc tttgccaagt agtgctcgta
    18541 agcatattgt ttcgatccac cggaattcaa cacatcttga tataagtgat aagccgggat
    18601 attgttggac cattctagtg actcacggac ggtttggaag gtgttcgatc cttcgttagt
    18661 agcattgacg attttctcgc cagcattttc tccttcttgc caagttgttg cataatctga
    18721 tacacgggat tctgatccga taagccccat gtcgattgca ggtccataaa caagaactgg
    18781 tttgattgat gagccagctt gacgttctgt atcgaaggca tggttatttt gattctgact
    18841 gtaattccgt ccgccaacga atccgtagat gcggccagtt ctgttatcca tcaatacatt
    18901 tccggtttct acttgactgc cagcaccatc atctaacatg tatccataat tttctacgcc
    18961 attttgcaat gcagcataga catctttatc gattgtcgaa tggattgtat atcctttatt
    19021 ttggatcgtt tgctgtgcct tttgataata agcgtcactg accgatgaat cagacatatc
    19081 agcgttgtct ttttcagcca attgttgtgc aatgattctt gttgcttcat tcatcacagt
    19141 ataatacaag aattctctgt cagtctgttc tgcgatttgt tgtggtagaa agtcttttgt
    19201 aaggtcatag gcttttgctt cttcgtattg ttctttcgta atttggcctt cacgatacat
    19261 actgaataaa acaaaatctt ttctggcaag gccggcagaa agatcttctt ttagcgcacc
    19321 tgtgttcgtg tatggactat acgtgatcgg gctttggggt aatccagcga tataagcagc
    19381 ttgcggcagc gtcacatctt ttgcatctac accaaagatt cctcttgcag cttcctggac
    19441 tccagcaatg ttttgtccct tattattacg accaaatggt gagacattca aatacgtagc
    19501 aatgatctca tcttttgaaa agtatttttc tacttgtgca gaaagaatga tctcgtttgc
    19561 tttacgtttg aatgttgttt catctgtaag gatctgctgt ttgactaatt gctgtgtcaa
    19621 agttgatcca ccagaagagc caataccagt agcttcagat actaatgctc gtaaaacagc
    19681 tttaggaacg taaccttggt gtttatcgaa gtattcatcc tctgtgctga taattgcagt
    19741 tttcaataaa ggtgaaattt tatcagatga aatagtcgtg cgcatcagat ctgtctggat
    19801 ttttgatatc tctgtattat ctgcataaac aatctttgac gtttctgtaa tgtttcctag
    19861 ttctgtctgc agtgcttttt tagtcggcaa ttgtgtgtct tcgacgagat aggcaaaata
    19921 gccagcgcct attccaatac ctagagctgc gaacatcaaa agaagaacag taataaaaac
    19981 agtcaatgat tgaaaaactc taaaaataat cttaggaaca aaccattttt ctttttttct
    20041 tctattctgt ttttttcgag tatttttgcg tggcaaaagg gtcacctcaa ctaatggttt
    20101 tatttcgcta attatagcaa ataatagaac aaaaaaacag acaaggctgt ttttggcagg
    20161 aatttctttt ttaaaagagt taaaacgtga gaaaatgatc ttttttataa aagagttctt
    20221 aagcttttct ttagagaaaa tttcagttac tatggagaac agggcaaaga aaaatcaatc
    20281 attttctttg tatatcatct taccaatata taggaattgt tagtaacaat tgcctttcaa
    20341 ggaggaatcc atccatgtta ttaggctcac acgtcagcat gagcggaaag aaaatgctgt
    20401 taggagcagc agaagaagca gccagttatg gatcttcgac ttttatgatc tatacaggcg
    20461 cccctcaaaa cactagaaga aaagccatcg aagagatgaa tattgatgcc ggaaaagcgt
    20521 acatggcaga aaacggtcta acaaatatcg tcgttcatgc cccttatatc attaatttgg
    20581 ggaatacgat caaaccagaa atgtttcctt ttgccgtcca atttctgaga gaagagattg
    20641 ttcgtgcgga agctttaggc gctactcaaa ttacacttca cccaggtgct catgtagggg
    20701 caggaacaga agccggaatt gctagaatta ttgaaggctt gaatgaagtt ttgacaaaag
    20761 aacagacggc acaaatcgct ttggagacaa tggcaggtaa aggtacggaa atcggtcgaa
    20821 catttgagga attagcgcaa atcatcgatg gagtaaaatt gaatgaaaaa ttatccgtta
    20881 cttttgacac ctgtcatacg aatgatgccg gttataatat taaagaagac ttttcaggtg
    20941 taatggaaga gtttgataag atcatcgggt tagatcggct taaagtactc catatcaatg
    21001 attctaaaaa tccgcaaggt tcgcataaag accggcacgc caatattggt tttggaacaa
    21061 tcggattcga cacgctgaat aagatcgtcc atgatccaat gtttgacaat atttcgaaaa
    21121 tcttggaaac tccctatgtc ggcaaagata aaaagaaagc ttacgcacca tatggaaaag
    21181 aaatcgccat gttcaaagca caaatattcg atccagaagt gtttcctgag ttattagcag
    21241 aagaagtgat actctaagat tttctatctg acagcagcaa aaaaggacca ggcacattgc
    21301 cttgtccttt tttgtttaag aaacaaagga gtgctttttg cagtcttttt catcatgcat
    21361 cttctccccc ctctttttaa atttagacaa acagggtata ctggtagaaa agtaaaaaaa
    21421 cgaaaagttt cacaagcaag tggcaaaacg tgattggaag gacgaaaaga tgctgaacac
    21481 tttaaaaccc ttgatcaacc aactaaaaaa gaaacataca tactttattc ttggcatagc
    21541 cctattattt acaattattc gtttgtattt atatagtaaa gcaatctatg gaacagacat
    21601 gtcggcaacc tatgatgacc agctgctgat tcgctatgct caaaatattt tggacggtaa
    21661 atggctaggg gagtatacga ctacaacact ttccaaagga atctcctaca gcttattttt
    21721 agtacttgca cataaactgc atctttctta tgcagttttg ttcggcatgt tcagtatttt
    21781 tgccagtata ttggttgcac tcgcgtttaa accgatcgtg aagaacaagt atcttctttt
    21841 aagtttctat ttttattttt tgttttctcc gattagtttt acacatgaat attccactcg
    21901 aacgtatcgt aatgccctcg tgattccggc tgttgagatc attatcgctt gtttactagc
    21961 tatttattac cgtaaatata gttccagcaa aaaaatgctg ccgtggtttt tagggctagc
    22021 tgtttctttt cctttctttt ggttcattcg cgaagattcc atctggcttc ttccttttac
    22081 tgtagtcgcg ttaggcatca gtttcgtcca gatcttgcta ggacaagact tttctttcaa
    22141 agaagcaaag aagttaaaag aacgaccatt tctcctttcg aaacaagaat ggctgaaact
    22201 ttcattgttt ttactccctc tagtcggttt ctccatcgtc tatcagtgga tcgaatataa
    22261 aaacgagaca acatatagta ttgccgccat caatgaccgt tcgagtggcg aatttggacg
    22321 tttgatgaaa cagctgatcc gaatagatga cgaaacgaac ttaaataaag aaaacagtga
    22381 gatatgggtc tcgcatgctg cattaaataa agcattagac gcatctccta catttcatgc
    22441 tgtttctact cgtattgacg aattgtatac gactcatgcg tggacccaag gtggaaaagt
    22501 aaaagaatta ccaggagata tcattttttg ggcattgcga gatgtggtaa gcgaatctgg
    22561 ttattaccaa aacaatgcaa aagaaaccaa tgatttttgg aaaaaagtca atcaagaatt
    22621 agaagaagcc tatcaaaagg gaactatcaa aaagaaaaaa gaattctatc tgatgggatc
    22681 aggggatgga aagacgatga atgatctgcc aatcgtattt gcttttctga aatcaggata
    22741 tgcctatgca tggcgataca aagatttcca tcaagggggg aattatagtt tcggtacgca
    22801 agaacaagtc gaacaggccc aagaattatt gaatcttcca ctaatggata attggatcga
    22861 tagcagtgat ccgagaacac ctgatttcca gttgacaaaa acagcaaaag tcgcgaatgt
    22921 catgataaaa atttaccaag ttctggccat tcccgtgctg attgcttcaa tagcagggat
    22981 attacttatg atactaggaa ccgcatttgc aaaagctgat cgtgcctatt atagttcctc
    23041 tttgattgta gtcaccggat taatactgac acaattggtt tttcttttcg gcgtctcgtg
    23101 gttttgttct tatgcgccag aaaaaaagga ttatttttta agtgtctaca ctggcgcagg
    23161 cgtgccatta acgcaattca tcgtagtaac aagcatgcta gttttcagta aattgaatct
    23221 gaaaaaagct ttatcttcca aataaaaaca tactaagatt agaggagaac atcattgacg
    23281 aatgatgttc tcctctattt tctattttta gattatagtg aagagtgaaa gaaagttcga
    23341 acaaagcctt gaggactatg agtccctatc aaaaaccgaa cttctttact gtcattttag
    23401 aatcaggttt acgtatgttg gggccatgag cccgtgtata ggaaattgga atcgaaatga
    23461 agcagtaaag ttctttcaaa acttaaaaag gaggaaaaca aatgccttac attcttgcat
    23521 tagatgtttc aatgggacac agctacagtg tcctatacaa agacgacacc tgcttatttg
    23581 aagacgagat cgaacacact caaagaggat ttcatgcatt actcgaagag atccagcact
    23641 tgcctgaacg tccattgatt gtttttgaag caacggggat ttattccaga ccagtcgaaa
    23701 agttctttca agatcatcac ttttcttact gtttgttaaa cccgttagaa gcgaaaaaac
    23761 agatggaaga aaacacctta tgcagttgga aaacagataa atcggatgcc catcggctcg
    23821 cacagactca tcttaaaaat caacgtcagc caaaagaagt acaaagcaat ttttacttag
    23881 agatgcgcga tttagcccgt ttttatcaag aaattgagaa gaaaatcact cgtctgcgca
    23941 tggatttaca caactgcctt cagttgactt ttccagagct tgaacagttc tttttaaaca
    24001 ggctgacccc ttacgcattg atattgatcc gtctttttcc ccatccagat tttgtattgg
    24061 catctactcg gacaaaaata aaaaataaac tgatcaacga aacacggaaa aaaatctccg
    24121 cgaatcgtgc cgagcaaaag gcagatcaaa tcatccacta tgcacagtgt gcctatccag
    24181 ctgttgaaaa agacagtatc cactgtcaaa aaacgatcta ttacgctgaa cttctccaag
    24241 atttactcga acaaaaa
//
LOCUS       DAZUJR010000041        23845 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.041, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000041 DAZUJR010000000
VERSION     DAZUJR010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23845)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23845)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23845
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.041"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..2131)
                     /locus_tag="ACG804_001537"
     CDS             complement(<1..2131)
                     /locus_tag="ACG804_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HFS4832473.1"
                     /translation="MTQEFIYAYKKMPDDLSVNGASLVDWEDLPEINRVLNGQYRFYG
                     NYSRSGQYRSYLKKGNFIKAKVPDGSWQYFEIYNVKKNLTSVSVTARHIGFMANKNFI
                     VKSFTDNGNGSQIMTNLKNSLAFDQKFNYLSNVGTTHQFTARQVAPVEAIIGSNNGNQ
                     NLTGVTSAELDMDNYDLKLVKQIGSDNGFRIDFGINLEAIEEEIDEESIVNSLYLVGG
                     VPDNDYDEDKEPIEYGYLEIDGVTNENRRIAKRENGDCKTVDELIKWGKTLFDNDRIH
                     EPKATHTVSMVALEHTLEYGDMYQELASLHFGDVAHVRAKELDIEIKERMVEYTYFPT
                     LGKYKDIVLGNDLSLYTSAVNTQAQELKKKIDNRTETLVQNVLNATAWITGNSGGHVV
                     FRPEKAPSEILIMDTPNVANAKRVWRWNLNGLGYSDNGVNGPFGIAITSKGEIVADFI
                     KVGTINAEVFETSFNAYGDVLKLVKGTLQIWNENKKIMELTKKGMEFWNRKESIGTIG
                     TTDSAGNPFPNAVTPTPLEENSLVIRTNGDGKYILISPTAEKGFVLLGNGKAYYFGDL
                     DIQGKLTVRGKEVIPGQNGGPSGGGETPGGYPDELKTDAEKRAWRIYDILCNNGFTKQ
                     SACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWDGKVYVQNLFN
                     AAGIKEPITSLDAQVRLLIWTFTNGQWM"
     gene            complement(2128..2832)
                     /locus_tag="ACG804_001538"
     CDS             complement(2128..2832)
                     /locus_tag="ACG804_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4832474.1"
                     /translation="MNPDEPNFIWKNRNAVIDMNCIIEAELPDIMPNKRYETYTIQGR
                     SGELTETFDDYEPFDLEIEGITIPHSKLREVKRWLTGKSQLITHNDPDKYLEAICSMD
                     KEVPFENEWGFFYTFDVTFRCQPLKRKIGEAPKIFHSSVMDIFDHGDEIAHPYLEIES
                     NGGDITIAVGDKSLTILNTLAATIVVDTQLGKAIQEGLNLFTRGDWPVLQPEWNQVKI
                     SGKFKEVRFWNRSVYL"
     gene            complement(2844..5153)
                     /locus_tag="ACG804_001539"
     CDS             complement(2844..5153)
                     /locus_tag="ACG804_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFS4832475.1"
                     /translation="MAGKESDVVLNFKTNGEVSYSKTIKEINKEMNLAAAEYKNQVSA
                     MDKDATQTEKLRAAKQKLEKQLGLAEQRSQMLREEYEKSVKETGEYSAESEKLYKQLL
                     NSETGENKLRTALEQTNDALKEQGDVSVDTAKKLQKIEETGEKVKGVGEKMSVGVTAP
                     IVAAGAAGLAAFGEVDEALDTIITKTGATGDQADRLSQSFKNVGSNTHLPLQTVGEAI
                     GEVNTQFGFMDKKLEDSTNYLLQYAEINDTDVSQSAISARQAIDAYGLEYDDLNSVLD
                     VTTKTSQNTGQSVDDLMQKAIDGAPQIKQLGLSFGEGVTLLGQFEQSGVDSSAALSSL
                     SKATVAYAKDGKSLSQGLEELQDKVKNAGSETEAINAAAEVFGTKGGPRMADAIRRGT
                     LNLEDLAKTAGESGGAVGDTFDATLDPIDQADQAMNNAKLAMADVGEAVQVSLLPFFE
                     KATSLLQEFSKWWGSLDQDTKNWIITIAGIAAAVGPVLIVLGSLMGSVTKIVGEVKSF
                     IGVWQGLAGLFGMSGGWFALAVIAIGALVTGLIWAYNNVKWFHDGVNSFFKGVSDVAV
                     EIFNFLSGYFGGFFDGVIANFNNFYNAGKRIFSGFLDFITGVFTGNWSKAWQGLVDIF
                     GGIFDGIVAVGKAPINAMIGLINGFIGGLNNIKIPKWVPGVGGKSFSISKLPYLAQGG
                     HLINGQAIVGEAGPELLTAKNGKTTVTPLSDEEKRKGISGRVSGGSIEQHIHIGKVDA
                     NNPSELDRMNRKFAKANKQAIRDLGGVPI"
     gene            complement(5348..5812)
                     /locus_tag="ACG804_001540"
     CDS             complement(5348..5812)
                     /locus_tag="ACG804_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832476.1"
                     /translation="MARLSDYGIHVEDLKNSAVVIIQGAEFPISFTMQTMEFIADVYG
                     GDYSQFESDMNAMLSKKEGQISSANLSPSDLKIMRALIYAMLRTGGLEEDPETIFKFL
                     GMSGEVLSAYSTCMEIFASQTFQVEDLKKSKKPQDFQKAQAKRKKNKKNRKR"
     gene            complement(5812..6438)
                     /locus_tag="ACG804_001541"
     CDS             complement(5812..6438)
                     /locus_tag="ACG804_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4832477.1"
                     /translation="MGKQDTFYFEGLDDILIAMMATPDSVGTAPTYSEVLRLPIATKI
                     GVKGNGTALEKWASSKMFRRVSRETKHELALDHVGIPIEVMDEIKGLVAKSGVTFSKN
                     TAREFPYFAFGFIGNIENGGKKAVWYPNTQLSNVIDEEYATAEEETKIDDVTANLVSI
                     GLKYNNVMYASFDSNRDGASLELFNKFIAQPVYDEEQWKTLAKVGGAG"
     gene            complement(6445..6810)
                     /locus_tag="ACG804_001542"
     CDS             complement(6445..6810)
                     /locus_tag="ACG804_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97-gp10 family putative phage morphogenesis
                     protein"
                     /protein_id="HFS4832478.1"
                     /translation="MPSNKNGFSEISDYLGNLSKVDPKKLSLESLEEAANFYLKQLLP
                     NIPKSLLKKKHMRDQIKVVVENDQVKVQFEETAFYWRFAENGTTNQRAQHFASGTYEQ
                     NKEKIEEIMTRKILDLWEG"
     gene            complement(6800..7138)
                     /locus_tag="ACG804_001543"
     CDS             complement(6800..7138)
                     /locus_tag="ACG804_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832479.1"
                     /translation="MSISFDELKTALKSTKLAVFRDKARLGTMYPYIVYSNVSNSKKM
                     ASGKVYKKLPYYQVSFFTLGTEQDLVVIEQALQNAGIPYSDFTGIQGDENDDTVTNYY
                     TYVRCVENAK"
     gene            complement(7128..7454)
                     /locus_tag="ACG804_001544"
     CDS             complement(7128..7454)
                     /locus_tag="ACG804_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HFS4832480.1"
                     /translation="MPKRQTNNLRWKAELLDIKTGTDGNDRPTTIYEFKRLIFYEELG
                     VTSQEKYLSQQAKTDVVRRIKVRWDKSITEKLSALKIDSVTYNITRIYTNPDAREMEL
                     SLAYVD"
     gene            complement(7435..7713)
                     /locus_tag="ACG804_001545"
     CDS             complement(7435..7713)
                     /locus_tag="ACG804_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail connector protein"
                     /protein_id="HFS4832481.1"
                     /translation="MEEQTKELSLEEKFKSHIHFEEGMDDSLLSFYLNMAKDYVKTAT
                     GGQQEYLILMVAGIAYEYRVSEDELDKAMNAMTPFIVQGAIQNAEETD"
     gene            complement(7715..9079)
                     /locus_tag="ACG804_001546"
     CDS             complement(7715..9079)
                     /locus_tag="ACG804_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFS4832482.1"
                     /translation="MDKELLKKMKARREQRLTELREKVESGELREADLEAVKEEIDSV
                     IDELNGIKDELGADSGTDETDDNTDDQSNSTDSDESRSGEDNDQEEDSDSEDSSENRS
                     GMITQQQRDGLLGSIKNGLEARAKMTKKQKDQQLRKAFANFVAGNISEAEARALGIEA
                     GNGSVTVPEVIASEVITYAQEENLLRKYGTVVRTSGDVKYPILVKKADANVNKKERST
                     DIAETAIQFDEILLNPAEFDALATVTKKLLKMSGVPVEDIVVEELKKAYVRKEINYMF
                     NGDDAGNENPGALAKKAVAFKKPLDLTASGAGQKLYDALIEFKNTPVTEVMKKGRFII
                     NRAALTAIEKMKTDDGFPLLRPFTQAEGGIGYQLVGYPVDWTDAADKKGEPDTPVLYF
                     GDFSAFKIQEVIGALEIQKLVEKFSGKNQIGFQIYNLLDGQLVYSPFEPAVYRYEITK
                     PVGG"
     gene            complement(9092..9661)
                     /locus_tag="ACG804_001547"
     CDS             complement(9092..9661)
                     /locus_tag="ACG804_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA];
                     GO_process: GO:0019082 - viral protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HFS4832483.1"
                     /translation="MKKKEIRTIDITNLSTRSDEETHTRTISGYAAVFNSQTLLWDDL
                     SEVIVPGAFSKAISNSDVRCLFNHDWSNVLGRTKSGTLRLEEDERGLKFEVDLPDTTV
                     ARDLVKSMERGDINQCSFGFVPTEETWDYNSEPMLRTIHEVELYEVSIVPLPAYEDTE
                     AALRSRDELEKNVEERKKLIKKINQALEA"
     gene            complement(9633..10820)
                     /locus_tag="ACG804_001548"
     CDS             complement(9633..10820)
                     /locus_tag="ACG804_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFS4832484.1"
                     /translation="MEKRGYIEDIFGHYTRYGQRYVTDSSIMESSDVYELVQDISNQV
                     ALATPIVIGPDGNEVKDHHLLNILKSPNDYLTGFEFTKLETNTLLINGETFPLTDRDQ
                     LHLAYGVTTKINERLQEEFEMNGQKIPGQMIRHIKNIGTDSLKGAGIIDLARNTLEGV
                     LSAEKVLTDKYTKGGLLAFMLKLDAHINPNNSAQTKIVKAILDQLEGTQNESDHSVKM
                     IPLGKGYSIETLKSPVDDAAILNYLGVYKKDLGKFLGINVDTYQSLMKTDIEKAMMYL
                     HNKAIKPILKNKSEHYTALFFMPNSGYRVEWKINILDFVPYSTKTNIGYNIVRTGITS
                     PDNVAEMLGFPKQNTPETQAIYISNDLSRIGQKNATDDSLPTNDQDLKGGDGNEEEGN
                     SHD"
     gene            complement(10884..12611)
                     /locus_tag="ACG804_001549"
     CDS             complement(10884..12611)
                     /locus_tag="ACG804_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HFS4832485.1"
                     /translation="MIEPGVNYADLFAKEVRKKPKKYPKTVRLAIDRWYQWKKRKDIW
                     FDVDRANEMMDWVESFIVHTKGEMVGKPFLLEPWEKFIYSWIYGWVKENEKGQIVRVT
                     REAYVQIPKKNGKTLIAVGSLGYAMYGEGALSVDCYACASDFAQAQYAAKPFAVTILN
                     NPILLEGTKIFRGPKGTVSSITYDYIHEDMAYSNKFIVQTKNIDNIEGSNPYFVLNDE
                     LHKQEKMEQYDNFKSAQISLPQPLMFNISTAGKGSSSVGMRVYREAKEVLKRDDNDSN
                     FVLIYEPNKNYDWTDRKVWEMCNPNWGISVDLSALESAFKTAQRSAHSKAEFLTKHLD
                     VFVNGADNFFEQDQVEPCLVTTQELGDLSGEPCYIGLDLSRTRDLTCVSLNFPTWDED
                     GKAVLKVKQLYFIPNEDLEFREKEDNVPYSDLAEQGFVEFCDGKMIDQDQILQYIEDC
                     MNLYDIQQVNYDPAMSDKLVEKLENLGLECVEVAQYPKVLNAPFDDVERLFYEKRIQF
                     DNPLFLYCTLNVVAITNINGQKAPSKRQSKKKIDGFVAFLCGHKETMNQMTDIDSDEL
                     DDYLSSIYR"
     gene            complement(12608..13060)
                     /locus_tag="ACG804_001550"
     CDS             complement(12608..13060)
                     /locus_tag="ACG804_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HFS4832486.1"
                     /translation="MTTKAQRKAIIDEKVSAEKARILEIMNLSDLYTITLDPLIESYL
                     DIFEIYQHKYLLWKEKGFPETQKFTNKSGATNQSKHPLAQQVETWADKKMKALDLLGL
                     TNKAKTGRLIAGGSTARKDEEITRPEVKPVDELAAHRNKWRKKAGAEK"
     gene            complement(13172..13552)
                     /locus_tag="ACG804_001551"
     CDS             complement(13172..13552)
                     /locus_tag="ACG804_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="HFS4832487.1"
                     /translation="MKYCQFDGCTNKIAKGIYCTEHKRSSRSRKKKQQAKSVYHHENK
                     PFYRTQAWKDMRQFIYEREGGHCQRCGQFIFGKRAHVHHIVPIKDNELLKLDPNNLML
                     LCSKCHPIVENETEDKKVFPSYFN"
     gene            complement(13549..13935)
                     /locus_tag="ACG804_001552"
     CDS             complement(13549..13935)
                     /locus_tag="ACG804_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho termination factor N-terminal
                     domain-containing protein"
                     /protein_id="HFS4832488.1"
                     /translation="MAMIKIRTSISGTEYWDSEKKRTVVVPKDQEPNFEVKEEKGILS
                     DGKSFVAVNGELIAHSSEILDSDGNTAANFDGDEATNDQSTEDTDELDNMTAKELRAY
                     AKKHGIDIPGAIRAKGDIINLIREVE"
     gene            complement(13937..14215)
                     /locus_tag="ACG804_001553"
     CDS             complement(13937..14215)
                     /locus_tag="ACG804_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832489.1"
                     /translation="MNDFHEAVLSIEVESSLAKVYKKAIEAENSPYRENWNGNHAHVQ
                     VENDDYRTGMNTLVISLLSHTLPNLQETIEWYERMGAKVIRTNYKGEN"
     gene            14263..14991
                     /locus_tag="ACG804_001554"
     CDS             14263..14991
                     /locus_tag="ACG804_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HFS4832490.1"
                     /translation="MRGVLMLQEVNIKYRDRQNTETIYLPNSCPHCGNIMTPYVYFGV
                     SSYSAFDNDRIFGVLVQCINDECNKFYSLQFINTFNEDEGYSENILIKDYYRPPIKID
                     LPENIEKVSPTFVDIYTQATQAKSEQLEQIAGVGYRKALEFLIKDYAISKNSEDEDKI
                     KKMLLGKTIENYLNDFPKLQRLAKAATWIGNDETHYVRRHTNKDVHDMDAFIKSAAQF
                     IAADYDADLADQFINGNNFMPTTN"
     gene            complement(15137..15613)
                     /locus_tag="ACG804_001555"
     CDS             complement(15137..15613)
                     /locus_tag="ACG804_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="HFS4832491.1"
                     /translation="MRFHWLKDYQELDEQILYLKWNLNKSKLELNRWVCGDLANVRIE
                     KNSRTSSLEENIQKIENELELLIEQKEEMLLLIDSFSGIDNQIVKMKYVDQMSLEDIA
                     ESVGYSSSYVRQRHAEIRKTLNFLDEYEHRQADRLKKENEIDFYNSEKYKEQLSLF"
     gene            complement(15573..15929)
                     /locus_tag="ACG804_001556"
     CDS             complement(15573..15929)
                     /locus_tag="ACG804_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832492.1"
                     /translation="MKKVNVIDLPVHFRGTNYFYASNLIQKKMSKDERKILANFYLVL
                     KIEQNVFSERRIVWEKQNQRLRRKNDVWNKRQSRMERLRKNKKATPFEIAAQYYSTIR
                     GGVCEISLVKRLPRTR"
     gene            complement(15907..16092)
                     /locus_tag="ACG804_001557"
     CDS             complement(15907..16092)
                     /locus_tag="ACG804_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832493.1"
                     /translation="MKVYILAITEGTWMFPVGSGKIYKSKTAAYKAFEKYKKENGGGT
                     NAKILVADNWHEEGERN"
     gene            complement(16093..16365)
                     /locus_tag="ACG804_001558"
     CDS             complement(16093..16365)
                     /locus_tag="ACG804_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH/PUA domain-containing protein"
                     /protein_id="HFS4832494.1"
                     /translation="MIHELKILPEYFEAVTSGRKQFEIRKNDRDFKVGDQLILREYKK
                     YIKHELPGLTRPTFSYTGDSYKAEITYITDYMQKSGYVVLGIKGVN"
     gene            complement(16362..16562)
                     /locus_tag="ACG804_001559"
     CDS             complement(16362..16562)
                     /locus_tag="ACG804_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832495.1"
                     /translation="MKVREQFKIVSDEGNVYKIKIVNINEYREADHKYLVDLYMNDKY
                     LGEGFCGDSLFDDERILKEETE"
     gene            16690..16902
                     /locus_tag="ACG804_001560"
     CDS             16690..16902
                     /locus_tag="ACG804_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832496.1"
                     /translation="MNINNLVKLVEQRFKESGLEQLKKDNSPELFSNFTEDDIPTLKQ
                     LKYYSDYWTQTRENELNLEKLIIKKK"
     gene            complement(16935..17129)
                     /locus_tag="ACG804_001561"
     CDS             complement(16935..17129)
                     /locus_tag="ACG804_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832497.1"
                     /translation="MMIQLAGIQTGKIYFSGESKSEANQWLLKTYTNNKKLRKKYPDL
                     LLKDDQIMPEPMILTRKEGS"
     gene            complement(17142..17324)
                     /locus_tag="ACG804_001562"
     CDS             complement(17142..17324)
                     /locus_tag="ACG804_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832498.1"
                     /translation="MRATDPVIILEEAKFIWTHEEIEQARLLFSQGVKPSKVAEIMGQ
                     KILDVGLLLLHLAEKI"
     gene            complement(17321..17461)
                     /locus_tag="ACG804_001563"
     CDS             complement(17321..17461)
                     /locus_tag="ACG804_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832499.1"
                     /translation="MNEIAADHELSETALIDQIELARQYFVPYADTWSKHKNDIIFPE
                     EQ"
     gene            complement(17951..18316)
                     /locus_tag="ACG804_001564"
     CDS             complement(17951..18316)
                     /locus_tag="ACG804_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832500.1"
                     /translation="MIDAKQVQKQKDGMLMFEAYVLPFLNQFEVLECSASGEELEYVV
                     IRETKENVQKLNEFLCTINCWDMIAPGFLCPAMGEFLEYCRLEDAGTLDLAYLVYNYL
                     NINTDHLWFGTAERKWVVR"
     gene            complement(18356..18658)
                     /locus_tag="ACG804_001565"
     CDS             complement(18356..18658)
                     /locus_tag="ACG804_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HFS4832501.1"
                     /translation="MDELIAKVEQWAKDKGLDQADFSKQMLKTVEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLDFAYDEIKGRTGKMVNGVFVKSSDLK"
     gene            complement(18658..18957)
                     /locus_tag="ACG804_001566"
     CDS             complement(18658..18957)
                     /locus_tag="ACG804_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832502.1"
                     /translation="MDKKAAMQRIIELTYSEDWQEDKKIVAEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAKQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            complement(18950..19114)
                     /locus_tag="ACG804_001567"
     CDS             complement(18950..19114)
                     /locus_tag="ACG804_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832503.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            complement(19120..19389)
                     /locus_tag="ACG804_001568"
     CDS             complement(19120..19389)
                     /locus_tag="ACG804_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832504.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDGTQLRNLAYTKLLFIDCVKGLQKHLNELEQV"
     gene            complement(19401..20150)
                     /locus_tag="ACG804_001569"
     CDS             complement(19401..20150)
                     /locus_tag="ACG804_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4832505.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            complement(20147..20839)
                     /locus_tag="ACG804_001570"
     CDS             complement(20147..20839)
                     /locus_tag="ACG804_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative HNHc nuclease"
                     /protein_id="HFS4832506.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGGEK"
     gene            complement(20845..21516)
                     /locus_tag="ACG804_001571"
     CDS             complement(20845..21516)
                     /locus_tag="ACG804_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HFS4832507.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            complement(21509..21850)
                     /locus_tag="ACG804_001572"
     CDS             complement(21509..21850)
                     /locus_tag="ACG804_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832508.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            complement(22028..22726)
                     /locus_tag="ACG804_001573"
     CDS             complement(22028..22726)
                     /locus_tag="ACG804_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HFS4832509.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            22813..23283
                     /locus_tag="ACG804_001574"
     CDS             22813..23283
                     /locus_tag="ACG804_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832510.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            complement(23326..23505)
                     /locus_tag="ACG804_001575"
     CDS             complement(23326..23505)
                     /locus_tag="ACG804_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832511.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(23492..23830)
                     /locus_tag="ACG804_001576"
     CDS             complement(23492..23830)
                     /locus_tag="ACG804_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HFS4832512.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
BASE COUNT         6633 a         5031 c         3681 g         8500 t
ORIGIN      
        1 ccatccattg tccatttgta aatgtccaaa taagcaatcg aacttgtgca tctaagctcg
       61 ttattggttc tttaatacct gcagcattaa ataagttttg aacataaact tttccatccc
      121 atgttgctgg accaacaaga ggatatgaag aaccatccca ctgaactaat ccgtatgctg
      181 gtccacctat ttgaacagta tcaggatcaa aagttcctcc tgtttcttgt tgaatgttcc
      241 ccaatattcc acatgcagat tgtttcgtaa atccgttatt acacaaaata tcgtatattc
      301 tccaagctct cttttctgca tctgttttta attcatcagg atacccacca ggtgtttctc
      361 ctccgccaga tggaccgcca ttttgtcctg gtatcacttc tttacctcta acagtaagtt
      421 ttccctgaat atctaaatca ccgaaataat atgcttttcc gtttcctaat aacacaaatc
      481 ctttttctgc agttggagaa attaaaatgt attttccatc gccatttgta cgtattacca
      541 aagaattttc ctcaagaggt gtaggtgtta cagcatttgg aaatggattt cctgctgaat
      601 ctgttgttcc gatcgttcca atggattctt ttctattcca gaattccata ccttttttgg
      661 ttagctccat gatttttttg ttttcattcc aaatttgaag cgtgcctttt acaagtttta
      721 acacatcacc ataagcatta aaggaagttt cgaatacttc tgcatttatt gttcctactt
      781 tgatgaagtc agcaacaatt tctccttttg atgtgatagc aataccgaac gggccattta
      841 ctccgttgtc tgaataacct aagccattta aattccaacg ccacactcgc tttgcattcg
      901 ccacatttgg agtatccatg ataagaatct ctgatggagc tttttctgga cgaaaaacga
      961 catgcccacc agaattacca gtgatccatg ccgtcgcatt caacacattt tgaactaacg
     1021 tttctgttcg attgtcgatt ttctttttca attcttgtgc ttgagtattt actgccgaag
     1081 tgtacagtga taaatcatta cctaaaacaa tatccttata tttcccaagc gttgggaaat
     1141 aagtgtattc gaccatacgc tcttttatct cgatatctag ctctttcgcc ctaacatgag
     1201 cgacatcacc aaagtgtaaa gacgctagct cttgatacat gtcaccgtat tcgagtgtgt
     1261 gttccaacgc caccatactg actgtatgag tagcttttgg ctcatggata cgatcattgt
     1321 caaataaggt tttgccccat ttgatcaatt catcaactgt tttacaatct ccgttttcac
     1381 gtttggcaat acgtcgattc tcgttggtta ctccatcaat ttctaaataa ccatattcga
     1441 taggttcttt gtcttcatca taatcgttat caggaacacc gccaaccaaa tacaaactat
     1501 tgacaattga ttcttcatca atttcttctt cgattgcttc taaattgatg ccaaaatcaa
     1561 tccgaaaacc attatctgat ccaatctgtt ttaccagttt caaatcatag ttatccatat
     1621 caagttccgc gctagtcacg ccagtcaaat tttgattacc gttatttgaa ccaatgattg
     1681 cttcaactgg cgcgacttgt cttgctgtaa attggtgcgt tgtccctaca ttcgaaagat
     1741 agttaaattt ttgatcaaat gccaaactgt ttttaagatt ggtcatgatc tgagacccat
     1801 tgccgttatc cgtaaacgac ttgacaataa agttcttatt ggccataaaa ccaatatgcc
     1861 gagctgttac agaaacggag gtcaaattct ttttgacatt ataaatttca aaatattgcc
     1921 atgatccatc tggtaccttc gcttttataa aatttccttt ttttaaataa gagcgatact
     1981 gtccgcttct tgaatagtta ccataaaaac gatattggcc attcagcaca cgattgattt
     2041 ctggcaaatc ttcccaatca actaacgacg ctccgttcac gctcaaatca tctggcattt
     2101 ttttataagc ataaataaat tcttgcgtca cagatacaca ctcctattcc aaaaccgcac
     2161 ttctttaaat tttccggata tttttacctg attccattca ggctgcaata ctggccaatc
     2221 accacgcgta aataaattca aaccttcttg tattgctttt ccaagctgag tatcaaccac
     2281 gattgttgca gctaacgtat taagtattgt taggctttta tcaccgacag cgatcgttat
     2341 atctcctccg ttcgattcta tttccagata gggatgtgca atttcgtcac catgatcaaa
     2401 aatatccata acactagaat gaaaaatttt aggtgcttca ccgatttttc ttttgagtgg
     2461 ctgacaacga aaagtaacat cgaatgtata aaagaagccc cactcgtttt cgaaagggac
     2521 ttctttatcc atgctgcaga tagcctctag atacttgtct ggatcattat gtgtgattaa
     2581 ttggctttta ccagtgagcc atcgtttgac ttctctcagt ttcgaatgtg gaatagtgat
     2641 cccttctatt tccaaatcaa aaggttcata gtcatcaaac gtctccgtca attctccgct
     2701 tcggccctga atcgtgtaag tttcgtatcg cttgttcggc ataatatctg gaagctctgc
     2761 ctcaatgatg caattcatat caattactgc attccgattt ttccaaataa aatttggttc
     2821 atctggattc ataaattgtc gactcaaata ggaacacctc ccaaatcacg aatagcctgt
     2881 ttgtttgctt tagcaaattt acgattcata cgatctaact cagatggatt gtttgcatcg
     2941 actttgccaa tgtgtatatg ctgttcaatg ctacctccag aaactcttcc actgatccct
     3001 ttgcgttttt cttcgtctga taatggagta actgtggttt taccattctt ggcagtcagt
     3061 aactcaggtc cagcttcacc aacaatcgct tgtccattga ttagatgacc gccttgtgct
     3121 aaataaggca gttttgaaat agaaaatgat tttccaccta caccaggaac ccattttggt
     3181 atctttatat tattcaatcc accaataaat ccattgatca atccaatcat ggcattaata
     3241 ggagctttcc ctacagcaac aataccatcg aaaatacctc caaaaatatc aactagacct
     3301 tgccatgctt ttgaccaatt ccctgtaaat actccagtga taaaatctag aaaaccactg
     3361 aaaattcgtt ttccagcatt ataaaaatta ttgaaatttg ctataacacc atcgaaaaat
     3421 ccaccaaaat aaccacttaa aaaattaaat atttcaacag ctacatctga aacacctttg
     3481 aagaaagaat tcactccatc atgaaaccat ttaacgttat tatatgccca aattagtcca
     3541 gtaactaatg cgccaatagc tataactgct aatgcaaacc agcctcccga cattccaaat
     3601 aaaccagcaa gtccttgcca aactcctata aaacttttaa cttccccaac gatttttgta
     3661 acagatccca taagtgaacc aagaacgatt agtactggtc caactgctgc cgctatacca
     3721 gcaattgtta tgatccaatt ctttgtatct tgatctagag acccccacca tttagagaat
     3781 tcctgtaata aggaagttgc tttttcaaaa aaaggcaaaa ggcttacttg gactgcttca
     3841 cctacgtcag ccattgctaa ttttgcattg ttcatagctt gatcggcttg atcaattggg
     3901 tcgagagtag catcgaatgt gtctcctaca gctcccccac tttctccagc agtttttgct
     3961 aaatcttcca ggttcaaagt acctctacga attgcatcgg ccattctagg accgccttta
     4021 gtcccgaata cttctgctgc tgcattgatg gcttctgttt cagaacctgc attttttacc
     4081 ttgtcttgta gttcttctag tccttgactt aaagattttc cgtctttcgc ataagccact
     4141 gttgctttag ataaactact taaagctgcg cttgaatcaa caccagattg ctcaaattgt
     4201 ccaagtaaag tgaccccttc accaaagctc aaccctaatt gtttaatttg tggtgcgcca
     4261 tcaattgctt tttgcatcaa gtcgtctaca gattgaccag tattctgcga tgttttcgtt
     4321 gttacatcaa ggacagaatt caaatcatca tattctagtc cataagcatc aatagcttgt
     4381 cgagcagata ttgctgattg cgaaacatct gtatcattga tttcagcgta ctgtaggaga
     4441 taattggttg aatcttccag ttttttatcc atgaatccaa attgtgtatt tacctcacca
     4501 atagcttccc caaccgtttg taaaggtaaa tgagtatttg aaccaacgtt tttgaaagac
     4561 tgtgaaagtc tatcagcttg atcacctgtt gctccggttt ttgtaatgat ggtatcaagt
     4621 gcctcgtcaa cttcaccaaa tgctgcaagt cctgctgctc ctgccgctac aataggcgcg
     4681 gttactccaa cagacatttt ttcaccaacg ccttttactt tctcacctgt ttcttcgatt
     4741 ttctggagtt tttttgctgt atcaacagaa acgtcacctt gttctttaag tgcatcgttc
     4801 gtctgttcta atgctgtacg aagtttattt tctccggttt cagaattgag taattgttta
     4861 taaagttttt ctgattcagc agaatattca ccggtttctt tgacagattt ttcatattcc
     4921 tctctcagca tttgagatcg ttgttcagcc aatcctaatt gtttttctaa tttttgttta
     4981 gccgctcgca atttttctgt ttgagttgca tccttgtcca tcgcagacac ttggtttttg
     5041 tactcggcag cggctaagtt catttctttg ttgatttctt tgattgtttt cgaataactg
     5101 acttcgccat tcgttttaaa attaagaacg acatcagatt ctttaccagc catttatctt
     5161 agcgctcctt tctaccacca aggcgattta tccatagtta cagattgagg tggttcaaaa
     5221 tcggtgtttt gttgtaacca ctgtaaataa gatttgagcc acaagttagg tgtagacttt
     5281 aaaaagaaac tctcactcca attcaataga gtgagagcaa cgtaaatata aaaactccaa
     5341 ggagttccta tctcttccga ttctttttgt ttttctttct ttttgcttgc gctttttgaa
     5401 agtcttgtgg cttcttggat ttttttaggt cttccacctg aaatgtctgg ctagcaaaaa
     5461 tttccataca ggtactataa gcagacaaca cctctccact cattcccaaa aatttgaaaa
     5521 tagtttctgg atcttcctct aaaccaccag tacgcagcat ggcataaatc aaggcacgca
     5581 tgatttttag atcactaggc gataagttag cagaagaaat ttgtccttct tttttagata
     5641 gcatggcgtt catatcagat tcaaattgcg aataatctcc accatacaca tctgctataa
     5701 attccatcgt ttgcatagta aatgaaatag ggaattctgc gccttgaata attacaacag
     5761 cagaattttt taagtcttca acgtgaattc cataatcaga taaccgagcc attaacccgc
     5821 acctccaact ttagccaatg ttttccactg ttcttcatcg tatacaggtt gagcaatgaa
     5881 tttattaaat aattctagag aagctccgtc tctatttgaa tcaaaacttg catacatcac
     5941 attattgtat ttcagtccga tggaaaccag atttgcagtt acatcgtcaa tttttgtttc
     6001 ttcctctgca gtggcatact cttcgtcaat cacattggat agttgtgtat taggatacca
     6061 aactgctttt ttaccgccat tttcaatatt tccaataaat ccaaaggcga agtacggaaa
     6121 ttctcgtgcg gtatttttgc taaacgttac tccgctttta gcaactaatc ctttgatttc
     6181 atccatcact tctatcggaa tacccacgtg atccaacgca agttcatgtt ttgtttctcg
     6241 cgacacacga cgaaacattt tgctggatgc ccatttttct aatgctgttc cattcccttt
     6301 gacaccgatt tttgtggcaa ttggcaatcg taaaacttca ctataagtcg gtgcagttcc
     6361 aacagaatct ggcgttgcca tcatcgcaat taaaatgtcg tccaatcctt caaaataaaa
     6421 agtatcttgt tttcccaatt aaaatcaccc ttcccataaa tcaagtattt ttctagtcat
     6481 aatttcttca attttttctt tgttttgttc atacgtacca cttgcaaaat gttgggcacg
     6541 ttgatttgtt gtgccatttt cggcaaagcg ccagtaaaag gccgtctctt caaattgaac
     6601 tttcacttga tcgttttcaa ctactacttt tatttgatcg cgcatatgtt tcttttttaa
     6661 gagcgactta ggaatattag gaagcaactg ctttagataa aagttagctg cttcttctaa
     6721 agattccaac gataattttt tcggatcaac ttttgaaagg tttcctaaat aatccgatat
     6781 ttcagaaaaa ccattcttat tacttggcat tttccacaca cctcacatat gtgtaatagt
     6841 tggttacggt atcgtcgttc tcatcacctt gtatacctgt aaaatctgaa tatggaatgc
     6901 cagcattttg cagcgcttgt tcaataacaa ctaaatcctg ttctgttcca agtgtaaaaa
     6961 aagagacttg gtaataaggt aattttttat agactttacc ggatgccatt tttttgctgt
     7021 tactcacatt tgagtacaca atgtatggat acatcgtccc taatctggct ttgtctctga
     7081 acactgctaa ctttgttgat ttcagcgctg ttttcaattc atcaaagcta atcgacataa
     7141 gctaaactca actccatttc tcttgcatcg ggattcgtat aaatgcgagt aatgttatac
     7201 gttacagaat caattttgag cgcacttaat ttctctgtga tggatttatc ccatctgact
     7261 ttaattcgtc tgacaacgtc tgtcttggct tgctgtgata aatatttttc ttgagaagtc
     7321 acaccgagtt cttcatagaa tattagacgc ttaaattcgt aaattgtagt tggacgatcg
     7381 tttccgtctg ttcctgtttt gatgtctagc aattcggctt tccatctgag attattagtc
     7441 tgtctcttcg gcattttgaa tcgctccttg cacgataaat ggcgtcatgg cattcatagc
     7501 tttgtcgagt tcatcctctg aaactctata ttcataggca atgccggcaa ccatcaaaat
     7561 aagatattct tgttggccac cagttgctgt tttgacataa tcttttgcca tatttaaata
     7621 aaaagagagc aaagaatcat ccatgccctc ttcaaaatga atatgtgatt tgaatttttc
     7681 ctctaaagac aattctttag tttgctcttc catcttaacc accaactggt tttgtaattt
     7741 cgtagcgata tactgccggt tcaaatggag aataaaccaa ttgaccatct agcaagttgt
     7801 aaatttggaa tccaatttga tttttaccag agaatttttc aacaagtttt tgaatttcca
     7861 aggcaccaat aacttcttga attttaaatg cagaaaaatc gccaaaatat aaaactggcg
     7921 tgtctggttc acccttttta tctgctgcat ctgtccaatc cacaggatag ccaactaatt
     7981 ggtaaccaat tccaccttct gcttgtgtga atggccgcaa caaaggaaat ccatcatctg
     8041 ttttcatttt ttcaatggca gtcaaagcag ctcgattaat aataaagcgt ccctttttca
     8101 tcacttctgt cactggtgta tttttaaatt cgattaatgc atcatataat ttttgcccag
     8161 cacctgaagc agttagatct aaaggttttt taaatgctac agcctttttg gctaatgcac
     8221 caggattttc atttccagcg tcatcaccat tgaacatata attgatttct ttacgcacat
     8281 aagctttttt caattcttcc acaacaatat cttcaactgg aacaccagac atttttaata
     8341 attttttagt tactgttgcc aaagcatcga attcggcagg attaagcaaa atttcatcaa
     8401 actgaatagc tgtttcagca atatcagttg aacgctcttt cttgtttaca ttcgcatctg
     8461 ctttcttcac aagaattgga tatttgacat ctcctgatgt tcgcaccact gttccgtatt
     8521 tacgaagtaa attttcttct tgagcataag taataacttc agatgcaatt acttctggga
     8581 cagtaactga accgttgcca gcttcaatcc ctaaagctcg agcttctgct tcagaaatat
     8641 ttccagctac aaaattagca aatgcttttc gtagttgttg atctttttgt ttcttggtca
     8701 tttttgcacg tgcctccaat ccgttcttaa ttgatccaag taatccatct cgttgctgtt
     8761 gagtaatcat tccagaacga ttttctgaac tatcttcact gtctgaatct tcttcttgat
     8821 cgttgtcttc accagaacgg ctttcgtctg aatccgtact attcgattga tcatctgtat
     8881 tgtcgtctgt ttcatcagtt ccagaatctg cgcctaattc gtctttaatt ccgttcaatt
     8941 catcaataac actgtcaatt tcttctttca cggcttctaa atctgcttcg cgtaattctc
     9001 ctgattcaac tttttcacgt aattcagtca atcgttgctc acgacgtgcc ttcatttttt
     9061 tcaataattc tttatccatg tatttttcct cctacgcttc tagcgcttga ttaatttttt
     9121 tgattaattt ttttctttct tcgacgtttt tttctaattc atcacgactt cttaatgcag
     9181 cttctgtatc ttcgtatgct ggcaaaggca caatagaaac ctcgtataat tccacttcat
     9241 ggattgttcg aagcattggt tcagaattgt agtcccacgt ttcttcagtc ggcacaaaac
     9301 caaaactaca ttggttgatg tctcctcgtt ccatagattt aactaagtcc cttgctaccg
     9361 ttgtgtccgg taaatcaact tcgaatttca aaccacgttc atcttcttca aggcgaaggg
     9421 ttccgctttt agtacgtcct agcacattgg accaatcgtg attgaacaaa caacgaacat
     9481 ccgaattact aattgccttt gagaatgcac caggaacaat cacttcgctt aagtcatccc
     9541 ataaaagtgt ttgactgttg aatacagcag cgtagccgct aatggtcctc gtatgagttt
     9601 cttcatcgga acgtgttgaa agattggtga tgtcaatcgt gcgaatttcc ttcttcttca
     9661 tttccatcac ctcctttcaa gtcttgatca ttcgttggta aggaatcatc tgttgcattt
     9721 ttctggccaa tcctagataa gtcatttgaa atatagatag cttgtgtttc tggagtattc
     9781 tgtttaggaa aaccaagcat ttctgccacg ttatctggac ttgtaatccc ggtacgaacg
     9841 atgttgtagc caatatttgt ttttgttgag taaggaacaa aatccaaaat attaattttc
     9901 cattccactc tatagccaga attaggcata aaaaaaagag cggtgtaatg ttcgctcttg
     9961 tttttcaata ttggtttgat tgctttgttg tgcagataca tcatcgcttt ttcaatatct
    10021 gtcttcatca gcgattgata cgtatcaaca ttgattccta gaaattttcc taagtctttt
    10081 ttgtaaacac ctaaataatt caaaattgcc gcgtcatcaa caggactttt taatgtctcg
    10141 atggaatatc cttttcccaa aggaatcatc ttaacagaat gatcactctc attttgcgtt
    10201 ccttccagtt gatccaatat agctttgaca atttttgttt gggcgctatt atttggattg
    10261 atgtgggcgt ctagtttaag catgaacgca agtaaaccgc ctttagtata tttgtccgtc
    10321 aaaacttttt cagcgctcag aacgccttct agagtgtttc ttgcaagatc aattattcca
    10381 gcacctttta atgaatcagt tccgatgttc ttaatgtgtc gaatcatttg accaggtatt
    10441 ttttgaccat tcatttcaaa ttcttcttga agtcgttcat tgattttagt tgttacaccg
    10501 tacgccaaat gaagctgatc cctatccgtt aatgggaatg tctcaccatt gatcaataaa
    10561 gtatttgttt ccaatttggt aaattcgaat cctgtcaaat aatcattggg actcttcaaa
    10621 atatttagta agtgatgatc tttgacttcg ttgccgtcgg gaccaataac aattggtgtg
    10681 gccaatgcca cctgattaga tatgtcttga actaattcat aaacatcaga agattccatg
    10741 atagatgaat ccgtcacata tctttgacca taacgtgtgt agtgtccaaa aatatcctcg
    10801 atatatccac gtttttccat aaaagaatag actgcattcg ataaccgatc acgtaatttc
    10861 aatttttttc accgcctttc tatttatcta tagatggaac ttaggtaatc atctaactca
    10921 tctgaatcaa tatctgtcat ttgattcatc gtttccttat gaccacacaa aaacgccacg
    10981 aacccatcaa tctttttctt tgattgacgt ttacttggcg ctttttgtcc attgatgtta
    11041 gtaattgcta caacgttcaa agtgcaataa aggaataatg gattatcaaa ttgaattcgt
    11101 ttctcataaa acaaccgttc gacatcgtca aaaggagcat tcaatacttt aggatattga
    11161 gcaacttcaa cgcattccaa tcctaagttt tctaatttct caacaagttt gtcactcatc
    11221 gctggatcat aattcacttg ctgaatatca tataaattca tgcagtcctc tatgtactgc
    11281 aaaatctgat cttgatcaat catttttccg tcgcaaaatt caacgaaacc ttgttcagcc
    11341 aaatcactgt aaggaacatt atcttctttt tctcgaaact ctaaatcttc attcggaata
    11401 aaataaagtt gctttacttt aagaaccgct ttaccatctt catcccatgt tgggaagttt
    11461 aaagatacac aggtcaaatc tcgtgtacgt gataaatcta aaccgatata acatggttcg
    11521 ccacttaaat caccaagttc ttgtgtggta actaaacatg gctctacttg atcctgttca
    11581 aagaaattat ccgcgccgtt cacaaataca tccaagtgtt tcgttagaaa ttcagctttg
    11641 gaatgagctg accgttgcgc tgttttaaat gccgattcta aagcagataa atcgactgat
    11701 attccccagt taggattgca catttcccag acttttctat ccgtccaatc ataattttta
    11761 tttggctcat agattagaac aaagtttgaa tcattatcat cacgtttcaa cacttctttt
    11821 gcttcgcgat atacacgcat tccaacagac gacgaacctt tcccagcagt tgagatatta
    11881 aacatcaatg gctgtggtaa agatatctga gcagacttaa aattgtcata ctgttccatt
    11941 ttctcctgtt tatgcaattc atcgttcaat acaaaatatg gattggatcc ctcgatatta
    12001 tcaatattct tggtttgaac aataaattta tttgagtaag ccatatcttc atgaatatag
    12061 tcataagtaa tactagaaac agttcccttt ggccccctaa atattttagt tccttcaagt
    12121 aggattggat tgtttaagat tgtaactgca aaaggtttgg cagcatattg cgcttgagca
    12181 aaatcagatg cgcaagcata gcaatcaact gataacgccc cttctccgta cattgcatat
    12241 cctaatgaac cgacagcaat caatgtttta ccattctttt ttggaatctg gacataagcc
    12301 tcacgagtaa cgcgtacaat ttggcctttt tcattttctt taacccaacc ataaatccaa
    12361 gaataaataa atttttccca gggttctaaa agaaacggtt ttcccaccat ttctcctttt
    12421 gtgtgaacaa taaatgattc tacccaatcc atcatttcat tcgcgcgatc tacatcaaac
    12481 caaatatctt ttcttttttt ccactgatac cagcgatcta ttgctaaacg aacggtctta
    12541 ggatacttct taggtttctt tcttacttct tttgcaaata aatcagcata atttacacca
    12601 ggttcaatca tttttcagca cctgccttct tacgccattt atttctgtgc gctgctagtt
    12661 catctactgg ctttacttct gggcgtgtaa tttcttcatc ttttcttgcg gtcgatcctc
    12721 cagcaattag tctaccagtt tttgctttgt ttgttaatcc taataaatct agagctttca
    12781 tcttcttatc tgcccaagtt tctacttgtt gtgccaatgg atgttttgat tgattagtag
    12841 ctcctgattt attcgtgaat ttttgcgtct ccggaaatcc tttttccttc cacaataaat
    12901 atttgtgttg gtaaatttca aaaatatcca agtatgattc gattaatgga tcaagagtga
    12961 tggtgtacaa atcagacaaa ttcattattt ctaagatacg agctttttca gcacttactt
    13021 tttcatcaat aatcgcttta cgttgcgctt tagtcgtcat ttttgtatac accccccttt
    13081 gttttttgaa aaatttgacc taacgatgcg cgtgactccc cgctacccta tctccccacg
    13141 cgaaaaaatt ttgaaaatga ataggggggc ttcaattgaa atacgaagga aaaacttttt
    13201 tgtcttccgt ttcgttttca acaattggat gacattttga acataatagc atgagattgt
    13261 ttggatcaag cttaagcagt tcgttgtctt tgattggtac aatgtgatgg acgtgtgctc
    13321 tctttccaaa tatgaactga ccacaccgct gacaatgacc accttctctt tcataaataa
    13381 attgacgcat atctttccat gcttgcgttc gatagaatgg tttgttctca tgatgataaa
    13441 cagactttgc ttgctgcttc ttcttgcgtg atctgcttga tctcttgtgt tcagtacagt
    13501 agataccctt tgctattttg ttcgtgcatc cgtcaaactg acagtatttc attctacttc
    13561 acgaataaga tttatgatat cgccttttgc acggatagca ccaggaatat caataccatg
    13621 tttcttagca tatgcacgca attcttttgc agtcatattg tccagttcat ccgtatcttc
    13681 agtggactga tcattagtag cttcgtctcc atcaaaatta gcagcagtgt ttccatcgct
    13741 atcaagaatt tcactgctat gagctatgag ttcgccattg acagcaacaa atgatttgcc
    13801 atcactcaaa attccttttt cttcttttac ttcaaaattt ggttcttgat ctttcggaac
    13861 aactactgtc cttttctttt ctgaatccca atactctgtt ccactaatgg atgttctaat
    13921 tttgatcatt gccattttaa ttctctcctt tgtaatttgt acggattact tttgcgccca
    13981 ttcgctcata ccattcaatc gtttcctgca gattgggtag agtgtgtgac aataaagaaa
    14041 taactaacgt attcattcca gttctgtaat catcattctc cacttgcaca tgtgcatgat
    14101 taccattcca attttctctg tacggactat tctctgcttc aattgctttc ttataaactt
    14161 tagccaaact tgattctact tcaatactaa gtaccgcttc atgaaaatca ttcatttgtt
    14221 tactctccta tcagatattt tgtggtatga tttataaaaa agatgcgagg tgttttaatg
    14281 cttcaagaag ttaatattaa gtatcgtgat cgtcaaaata cagagacaat ttatttgcca
    14341 aatagttgtc cgcattgcgg aaatataatg actccgtatg tgtattttgg ggtttcatca
    14401 tatagtgcgt tcgataatga tagaatcttt ggcgtattag tacagtgtat aaatgatgag
    14461 tgcaacaaat tttatagttt acaatttata aatacgttta atgaagatga aggatattct
    14521 gaaaatattt taattaaaga ttattaccgt ccgccgatta aaatagattt accagaaaat
    14581 attgaaaaag tttctcctac atttgttgat atttatactc aagccacaca agctaaatct
    14641 gagcaattgg aacaaattgc tggagttggt tatagaaaag ctctagaatt tctaattaaa
    14701 gattatgcaa tatctaaaaa ttcagaggat gaagataaaa taaaaaaaat gttattaggt
    14761 aaaacaattg aaaattattt gaatgatttt cctaaactcc aaagattagc caaagctgct
    14821 acttggattg gtaatgatga aacgcactat gttcgtagac atactaataa agatgttcat
    14881 gatatggatg catttattaa atcagcagcg caatttatcg cggctgatta tgatgctgat
    14941 ttagctgatc aatttataaa tggaaataac tttatgccaa ctactaatta aaagaataaa
    15001 agagccacag ataccaatta ataaaacggt tgggatatct tggctctttc atattttttt
    15061 gacactaata gaatatcatg ctgctaacaa tgtttacata gctacaatga ccgaacattt
    15121 agtgaacagt gtaattttag aataaagaga gttgttcttt gtacttctcg ctattgtaaa
    15181 aatcaatttc gttttctttt ttcaatcggt cagcttgtct gtgttcatac tcatctaaaa
    15241 agttcaatgt ctttctaatt tctgcatgtc gctgtctgac atacgatgag ctatacccaa
    15301 cagattcagc aatatcttct aagctcattt gatcaacata tttcatctta acaatttgat
    15361 tatcgatacc agaaaagcta tctatcagca ataacatttc ttctttttgc tcgatcaaca
    15421 attccaattc attttctatc ttttggatat tctcttctaa agaagaagtt ctcgaattct
    15481 tttcgatgcg gacgtttgct aaatcaccac agacccatcg attcaattca agcttacttt
    15541 tattaagatt ccactttaag taaagaatct gctcatctag ttcttggtaa tcttttaacc
    15601 aatgaaatct cacaaacgcc accccttatg gtagaatagt attgcgctgc tatctcgaaa
    15661 ggggtagctt ttttattttt tcttagccgt tccattctgg attgcctttt gttccaaacg
    15721 tcgttttttc ttcttaatct ttgattttgt ttttcccata caattctcct ttccgaaaac
    15781 acattttgtt cgatttttaa tactaaataa aagttggcca gaatttttcg ttcgtcttta
    15841 ctcatctttt tttgaataag attactagca taaaaatagt tagtaccacg aaaatgaaca
    15901 ggtaaatcaa ttacgttcac cttcttcatg ccagttatca gccactagaa tctttgcgtt
    15961 agtgccgcca ccgttttctt ttttgtattt ttcaaatgct ttataagcag ctgtttttga
    16021 tttatagatt tttccggaac cgactgggaa catccatgtg ccctctgtga tagctaagat
    16081 gtatactttc atttaattca cccctttaat ccccaacact acatatccgg acttctgcat
    16141 gtaatcagta atataagtga tctctgcttt gtatgagtca ccagtgtaac taaatgttgg
    16201 tctcgttagt ccaggtaatt catgtttaat gtatttttta tattcacgta gtattaactg
    16261 atcaccaact ttgaagtcac gatcattctt gcggatctcg aattgtttgc gtccgctcgt
    16321 cactgcttca aaatattctg gtagtatttt tagttcgtgg atcattctgt ttcctccttc
    16381 aaaattcgct catcatcaaa aagtgaatct ccacaaaatc cttctcccaa atatttatcg
    16441 ttcatgtata agtcaaccaa atatttgtga tctgcttctc gatattcatt aatattaacg
    16501 atctttattt tgtaaacatt accttcgtcg ctcactatct tgaattgttc tctgactttc
    16561 accaccgttc ctcctctttt tgaaaaaatt ttagtgtttt tgtaagaccc cctaaatcag
    16621 cttttttatt tgatataata cttgtatcga ttaatcaaat cgaaattaaa tttaaaaagg
    16681 tgatttatca tgaatatcaa caatttagta aaactcgttg aacaacgttt taaagaatca
    16741 ggattagaac aattaaaaaa agataattct ccagaattat tttctaattt taccgaagac
    16801 gacattccta ctcttaaaca attaaaatat tattctgatt attggacgca aactcgtgag
    16861 aatgaattaa atttagaaaa actcattatt aaaaagaaat agcaactcca gcccacacgg
    16921 ctggtttttt agtttcaact tccctcctta cgggtcaaaa tcatcggttc cggcataatc
    16981 tgatcatcct ttagcaacaa atcaggatat tttttcctta gcttcttatt gttcgtgtaa
    17041 gttttcaata gccattggtt ggcttcgctt ttgctttctc cagaaaaata aattttccct
    17101 gtttggatgc ctgcaagttg aatcatcatt ttcacctcaa atcaaatttt ttctgctaga
    17161 tggagcaaaa gcaatccgac atcaagaatc ttttgaccca ttatttcagc tactttgctc
    17221 ggcttaactc cttgagaaaa gagcaagcgt gcttgctcta tctcttcgtg agtccaaata
    17281 aatttggctt cctcaaggat aattactgga tcagttgctc tcattgttcc tctggaaaaa
    17341 tgatgtcatt cttatgcttg gaccaggtat ctgcatatgg aacaaagtat tgtctagcta
    17401 attcgatttg atcaattaaa gcagtttctg ataattcatg gtctgcagca atttcattca
    17461 tactatcgcc ttcatctaaa cagataagac cgttgacgtt atcgattttt acatttgtga
    17521 ctgcttgact ttctccacgc tcataatatt ctacagttga tactgataca tcagcttcgg
    17581 agtttaattg cagaatctgt tactgccggg ataatttaat attcttttca taattcacct
    17641 tttttcctac tgacatcgaa tatttttcat gttatgatta gccgtgaaag gagagctata
    17701 ttatgtgttt acacatgatg tccttagctc attcggttct ttggaagctt ttttggaaat
    17761 aactctcagg ttcttgacgc aaatctcatt tattctttga aacaaaaaac ttccattttc
    17821 cgagagcttt ggatcacttc aaaagagatt tgcatttata tttctgtgac cttgagtcgc
    17881 gtaaagaacc ttacagcaat ggcggcaatt ccactttcag gaaaccgcct tttttcattg
    17941 atattggtgg ttagcggact acccattttc tttcggcagt gccaaaccac aaatgatctg
    18001 tgttgatgtt taggtagttg tataccagat aagctaaatc caaagtgcct gcatcttcaa
    18061 gacgacaata ttccaaaaat tctcccatag ctggacataa aaatcctgga gctatcatat
    18121 cccaacagtt aatagtgcaa agaaattcgt ttagcttctg aacgttttct ttggtttcac
    18181 gaattacaac atactccaat tcttctccgc tggcagagca ttccaaaact tcaaattgat
    18241 taagaaatgg tagaacatat gcttcaaaca tcaacattcc atctttctgt ttttgcactt
    18301 gttttgcatc aatcatgtct atcctcctat tcagttattt cttccattaa tggaattatt
    18361 tcaggtcact ggacttaacg aaaacaccat tgaccatctt tccagtccga cctttgattt
    18421 cgtcataagc aaaatccaag cactcgtata aatccatatc attttgcatt gccaagatga
    18481 tcaaggttac tactacatcg ccaattccgt ctcttaaacc atgttcatct tttctagcta
    18541 gagaagcggc aacttccccg atttcttcga ccgtttttaa catttgcttg ctgaaatccg
    18601 cttgatccaa tcccttatct tttgcccact gctctacttt cgcgattagt tcgtccatta
    18661 tttctcctcc acatacctaa actgtcttcc ttttgaatca atccataagc tcctagctct
    18721 atcccaaata atatttttgc tcagaccagt aatttcagat aactgtttag cggtacccgt
    18781 tactagaatt cgatcaccat gccagattgc aatctttctc ggcgttctcc gtttgggctt
    18841 ttcagtccac attgatttac cgagcttttg gacttctgca actatttttt tatcttcctg
    18901 ccaatcttct gaataagtca attcgataat tcgctgcatt gccgctttct tatccatccc
    18961 gacattctcc tttcagtaat ttgagtactt gatcaagtgc gctctcacgt ccgccatgaa
    19021 atgtgttgag ccacttgtct tcgtacgaca cactttgtct taaagcttct tgatgcatta
    19081 attcgatctg tgctgtaaat gtctttaggt ccatcttgtt tacacctgct caagttcatt
    19141 aagatgtttt tgcaagcctt taacacaatc aatgaatagt aatttggtat atgctaaatt
    19201 tcttaattgc gttccatcga tatagagtgc gaaatagtat ctgagtttac tccaactcga
    19261 acgatcattc ttaattcctt caattccagc ttcttcgagt tgatcatata cgtctctcag
    19321 gacgtctaat tcctcgccct ttttataatt cgctatttca ttaattagtt ctagataatc
    19381 gatcttcatt tttccacctc ttagaatggt gcttttgatt gtctattagc tcgttctagc
    19441 gcttttttct tgagataggc ttcttggtcg attgcccatt caggaagctt ctctcgtctt
    19501 cctgtgcgct tgtatccact gcttgcgttc ttaggttcac ttttttcttt ccttgcccaa
    19561 cttcgaatag ttgccaaata gtttttataa gtcttaccag atgattcaca atactctgac
    19621 agtcgttcga ttcgctcttg gtaatcatta gggaattctg ttttgagttt ctccatctgc
    19681 tcatctgaca aaagaacatt tttatactct ccgtatttat gacggacggg cttagccttc
    19741 gattttttcg aaggcggtaa ctctcttata tattcttttg tattattaaa tgtattatta
    19801 atagatgtat tattatcttt gactttttcg tcaatagggg tattgcgttt ttcgtcaata
    19861 gggtattgat taattcgtag gtacctattg attatttgat tggtaccctc tttgtaaatg
    19921 atttcccgat tcaagtatcc aaacttaatc aaatcactta cccatcgcga tatggtctct
    19981 ttattcacac catataaatc tgcaaagtac tcattgcctg cccaacaaaa gcctctttca
    20041 ttacacaagg ccgttatctc tccgtataac aacttagtat ttggtttaag tcttttgtcg
    20101 taccttacgt tggctggtat aatcgcataa taacttcgat gttctgtcat ttttcccctc
    20161 caatatttaa ctttttgatt gttttctggt ttaatttgat ccctttgatt tgatatttat
    20221 ttttgaaatt aatcacacct attttgtgct tctctgtgtg atggattctg cagagtgctg
    20281 caaatgtgta ctctgcatga tcaacttctt tgcgctttcg tcttcctagc gctttgtcaa
    20341 agtgatcgat gtcagctcct gttttgccac agatgcagca gactcttttt gtgatgcatt
    20401 tgtagaagta atattcttga ttcgcaggta aaatctcata gccttctttg aaaggaatat
    20461 gatgttcaaa gatgaaatct aagatgatat ttgctaagac attggcatca ctcacagttg
    20521 tattcgattc gtctttcagg cttattttgc gccctgtgac accttcaaaa cgaaagtaga
    20581 agaattcctt ccagaagtcc gttggcatgc ctgtatcgat aaaaatatcg cctatcagcg
    20641 catagatgaa gtttcgttgc tgtacggtga aacgtctagg atcaataaaa cgaatttcaa
    20701 tgactcgatc accatcgtag ccgtcataca tcgtctttag tcgatcaatg ttcacttcct
    20761 cattgatggt tgcgcttatg tcttttcctt tgaacttttt cagaaccgct gaatatgaat
    20821 cgattaatgg tttaaacact catatcactt cttatctaat tcttttctct tagctgctat
    20881 tgctcgctcc atcaaggcac attgctcata gcttaactgt tcaatagttt caacgttatc
    20941 agctaagagc cctaatttat ctgtctgctc attaacatat tcgattaagg ttttggtcat
    21001 atctttaccc atctgctcat tgaaagcttc tagaatcgtc tctagcatgt ttaatttctt
    21061 tgtatcgatt ctaggtggtg ttggaatatc ttccccttga aatacatata atcccagtcc
    21121 gtgtagagcc aatgctttca caaagcatcg cttcaatgag ttattgattt gcattgcatt
    21181 tggtttaaca actggttggt ttcgataatc taaaacagga aataattcgg tttccgtgtg
    21241 tcctttaacc gttactgaga cagatacata agtcccagtt tcatccataa gaaaaggttt
    21301 atattcctca acaagaaagt cttgatgagt tccagaaaca accctgtagt gtttgtactc
    21361 attaatagtt accgttgcct gtggatcatt ctttttcata atctcccacg cgtgagccca
    21421 agataaataa tcaaaatttc cttttttctt gagaatttta tttaacttac gactaaaaag
    21481 tttttcaaag ttcgttgtcc ctttgatttc actcatcaaa ttctgcctcc atttcagcaa
    21541 tgtatttctt acctggtccg taataagaga tatcaatcaa gttatctctg tcgtactctt
    21601 ctagcgcatc aatcaagcca tcttcgatga cgtaaatata ttcaggttta ttcgaatgct
    21661 tcgatagatg gataagataa acatgatccc aaatagttac atggttgcct aaatcatctt
    21721 gatcccaagc tagttcttca ttcgtcaaaa gatttcgtct gatttttcga ccacttgttt
    21781 cctcaatttt cggcttgccc caatcaggat caatcaaata ttgatctaga gtggaaagtt
    21841 ctttttccat atgctaaaat ctccttatga tgtgttttct ttgtgactct ttgcttgccg
    21901 gcggagtcac ttttttattt gttgccatgc tttttgcttg tcaatatgtt gttggcttag
    21961 gatgattggt ttatagtatt tccaccagca attagcaatt gccgtcccta ttcttagcgc
    22021 ttcagctcta ttcattgtca tcaccaaaaa gtctctgttg tctgttcagt tgatcaattt
    22081 ccatacggat cgcagtttct ggcaaccaca tttcaataaa tgaaacagca tcatcgaatc
    22141 tcttacgagg taactcgcca tatcttggga ttgaaaaggt acgtttaaat tcagaccaaa
    22201 attttgagaa tacttttttg ctgatttctt cataagctcg gctttctttt ccccctagaa
    22261 ctcccataac tttcatattt cctttttgct taatttcaaa ctcttgttgt ccgctaattc
    22321 gcatagtatc tttaagcatg gaaacatctt ttttaacatc tttcatttct tctaattgat
    22381 agatcatcat atcttcaatt gtttgaggaa cagtattctt gcgaataaca tcttccattt
    22441 cgttgaatgc ttcaatgtat ttttgtttga agtagatagc tttctttcct gtaaacccca
    22501 tagccagcaa gaaaaatcca tctctactaa tgaagaaaac tcgtcgattt ctgccatatg
    22561 aatctggttc attaccttct acaaacatct gtccaaaatt ggacacatct ttttttagtg
    22621 catcaatatc tcttaaaaca tgttgatgtt ttttctcgaa gctttctgcc acttgtaagc
    22681 tcgtagtcac agcttcttta tttttcaaaa ttactaattc ttgcattatt tcttctctcc
    22741 tttttggtat aatttagtta aaaactggtg gtgtttattt tgaatttttt tcacttaaca
    22801 atttttcaat ggatgtcaat aataagtttt atattgagta cgtttttaac agggataaaa
    22861 ataaaaggaa tgcgccctca actagaagtt gaacttaatg cttcttactt cgctgcagat
    22921 atgatttata caaaagtaat catttctaac tattcaacag aaccagctat gttagttaat
    22981 ttagaacttt catccgctaa cttaaaccgc agatggtcag ctactccatt taagaaatta
    23041 attgctaaag gaggatcagt cgatgataat agaatatact ctgaagctgt accgctaaat
    23101 attcctccta aaagtgctat atcttgttac cttgcatttg aagtagggaa aattaatttt
    23161 aataaactcc ttaatcacca aacaaaaatg atatttactc taaatagaac ccaaatccac
    23221 aaaattgttg atatcaaaaa tacaaacttc ccaatagaga aattagtgaa agaattaaac
    23281 tgagtaatag taatatacat tctagtttct cttttctatt catttttagt cagccccctc
    23341 ggttggcttt ttcgctctgt actcagcttc agcttcatca agccccataa aaatccaaac
    23401 catgtaaaca atcgttccta tcaacgcttg cctgcttccc caaagtccta aagcgtagat
    23461 gattagcggt gcgctgaaca ctagcgctct attaaatttt cccatccgct tgcctcctta
    23521 agatttccga aaaatttgtt tctaaaaatt caagtgtttt acttcttaaa aatagatatg
    23581 tgtctcttcc ttcaactgga taatagacaa atccattttt gtttttctcg atatcgataa
    23641 tatttctata tcttgggttc tttaaaactc tagaagtaaa ccaatcatat tttctgttaa
    23701 tccgttctag cacttctggc aacgtcatcc atctaccagt atcatcagct ttttttaact
    23761 cctcataatc cacttgggag ataattacat agccttctgg aattgggatt tttgcttcta
    23821 gatattgcat tagctgttcc tccct
//
LOCUS       DAZUJR010000042        23830 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.042, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000042 DAZUJR010000000
VERSION     DAZUJR010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23830
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.042"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(54..788)
                     /locus_tag="ACG804_001577"
     CDS             complement(54..788)
                     /locus_tag="ACG804_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HFS4832513.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1115..1525
                     /locus_tag="ACG804_001578"
     CDS             1115..1525
                     /locus_tag="ACG804_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HFS4832514.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1518..2219
                     /locus_tag="ACG804_001579"
     CDS             1518..2219
                     /locus_tag="ACG804_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HFS4832515.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2219..3805
                     /locus_tag="ACG804_001580"
     CDS             2219..3805
                     /locus_tag="ACG804_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4832516.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3824..4045
                     /locus_tag="ACG804_001581"
     CDS             3824..4045
                     /locus_tag="ACG804_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HFS4832517.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4042..4803
                     /locus_tag="ACG804_001582"
     CDS             4042..4803
                     /locus_tag="ACG804_001582"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HFS4832518.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5183..5692
                     /locus_tag="ACG804_001583"
     CDS             5183..5692
                     /locus_tag="ACG804_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HFS4832519.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5767..6306)
                     /locus_tag="ACG804_001584"
     CDS             complement(5767..6306)
                     /locus_tag="ACG804_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HFS4832520.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6446..7057)
                     /gene="rpsD"
                     /locus_tag="ACG804_001585"
     CDS             complement(6446..7057)
                     /gene="rpsD"
                     /locus_tag="ACG804_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HFS4832521.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7319..8170
                     /locus_tag="ACG804_001586"
     CDS             7319..8170
                     /locus_tag="ACG804_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HFS4832522.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8198..8833
                     /locus_tag="ACG804_001587"
     CDS             8198..8833
                     /locus_tag="ACG804_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HFS4832523.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8853..9626
                     /locus_tag="ACG804_001588"
     CDS             8853..9626
                     /locus_tag="ACG804_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFS4832524.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10034..10831
                     /locus_tag="ACG804_001589"
     CDS             10034..10831
                     /locus_tag="ACG804_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HFS4832525.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10809..11222
                     /locus_tag="ACG804_001590"
     CDS             10809..11222
                     /locus_tag="ACG804_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFS4832526.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11206..13851
                     /gene="mutS"
                     /locus_tag="ACG804_001591"
     CDS             11206..13851
                     /gene="mutS"
                     /locus_tag="ACG804_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HFS4832527.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13869..15977
                     /gene="mutL"
                     /locus_tag="ACG804_001592"
     CDS             13869..15977
                     /gene="mutL"
                     /locus_tag="ACG804_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HFS4832528.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRQTGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15999..16559
                     /locus_tag="ACG804_001593"
     CDS             15999..16559
                     /locus_tag="ACG804_001593"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphatase"
                     /protein_id="HFS4832529.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16644..18632)
                     /gene="treP"
                     /locus_tag="ACG804_001594"
     CDS             complement(16644..18632)
                     /gene="treP"
                     /locus_tag="ACG804_001594"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HFS4832530.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18855..19568
                     /gene="treR"
                     /locus_tag="ACG804_001595"
     CDS             18855..19568
                     /gene="treR"
                     /locus_tag="ACG804_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HFS4832531.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19645..20091
                     /gene="msrB"
                     /locus_tag="ACG804_001596"
     CDS             19645..20091
                     /gene="msrB"
                     /locus_tag="ACG804_001596"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HFS4832532.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20262..20864
                     /gene="ruvA"
                     /locus_tag="ACG804_001597"
     CDS             20262..20864
                     /gene="ruvA"
                     /locus_tag="ACG804_001597"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HFS4832533.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20877..21878
                     /gene="ruvB"
                     /locus_tag="ACG804_001598"
     CDS             20877..21878
                     /gene="ruvB"
                     /locus_tag="ACG804_001598"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HFS4832534.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21907..22485
                     /locus_tag="ACG804_001599"
     CDS             21907..22485
                     /locus_tag="ACG804_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFS4832535.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22537..23019
                     /locus_tag="ACG804_001600"
     CDS             22537..23019
                     /locus_tag="ACG804_001600"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HFS4832536.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23136..23510
                     /locus_tag="ACG804_001601"
     CDS             23136..23510
                     /locus_tag="ACG804_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832537.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
     gene            complement(23623..>23830)
                     /locus_tag="ACG804_001602"
     CDS             complement(23623..>23830)
                     /locus_tag="ACG804_001602"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832538.1"
                     /translation="NLTTFENFRHKIFTTNDYYISIPTNNPNNTFSFLTPYPASSPAS
                     RTFFYQKNLYHPIDSTNQPNAVML"
BASE COUNT         7781 a         4286 c         5115 g         6648 t
ORIGIN      
        1 taaaaaaact tggtacgcaa tcgctgtacc aagttttttt atttagcttt tgattaagcc
       61 ataaataata atttatataa gaatactgct acgacaccag cacagatagg tgctacaact
      121 ggtacccatg catatcccca ttgagaagaa cctttatgtt tcaatggaag aagtgcgtgt
      181 acaagacgtg gagcaaagtc gcgggctggg tttagtccag gacctgtagg accaccaagt
      241 gaagcaacta atgtccatac aaggaaacca agtgctaagt gagctgtacc aagattatct
      301 tggaagaatg gtgcttttgt aatacctagg gcaccaaaga ataaaacgaa tgaaccaaag
      361 aattcattga cgaaaccatt gaatttagaa ccaacgctgt tgattgttga gaatgtacct
      421 aacacatggt ttacgtcttc tgtttggtcg tagtaaggtt tgtaacaagc tactacgatc
      481 aattgtccaa tcgctgcacc aatcaattgt gcaatgatat aaggaacaac ttcagcccaa
      541 gggaatagac cattagatgc taaagcaatt gtaaatgctg ggttgatgtg gttaccgctg
      601 attccaccaa aaatcattgc tggcatcata accccgaatc catacccgac agcaatcagc
      661 atccagtcac tgccatatcc ttttgtacct tttaaatcta cgtttgctac agcaccgtta
      721 cctagaacga ttagtaatgc tgtaccaatc atttccgccg caagacgggt cattagtgag
      781 taatccataa atacctccaa aagttataaa aatgcaaaaa aaaaagaaac atcaacacga
      841 aaagcatcgg tgcagtgttt cgtgtcggaa ggatttctgc agtcttaaca aatgtgaata
      901 aaaaaatgaa ttccattact tataagaaac cagaccaaca gtaaaactcc aactcttttt
      961 aaaagttctc cacaaatcac caagcttaac tataaatata ccaaaaaaaa aacgtttttt
     1021 ttctcaaaaa ttgtatctta gaaacagcat gttttgaaac tttcagaaaa ggtttgttag
     1081 taaaatgaaa gctatacgta aggagtgttg tttgatgaaa ttttttcaag agtttttcat
     1141 tattattttc ttttctgtat taggagaagg catacggatt tttgctcatt tacctattcc
     1201 tggaagtatc ttaggtattc tttttttatt tttagcattt gaaatgcatc ttgttgatcc
     1261 tgaaaaaatc ggagcaactg gtgatttttt attgaataat ctagccattt tatttgttcc
     1321 tgctggtgta ggtttattgg aatattttga tgatattgct tcgatatggc ctgttttact
     1381 gggagcagtc gtcgtgtgtt ccatcgtcac gatggttgca gcgggaaaaa cggcagaagg
     1441 tgtagaagct ttgctgggct atgtccgtaa gaaaaaagca gaaagggtat ctgtaaacga
     1501 aatggaggag aatcaaattg actgagtttt ttgtgaatcc attatttggc ttaagtttga
     1561 ctttaggagt gtacgtatta tctgacaaat ttttgcggaa atataaactg cctgttttga
     1621 atcctctcgt attatcgatt gttgttatta tcttattttt gcatttttct gggatcagct
     1681 ataaagacta taatatcggg ggcaattttt tgactatgct gattactcct gcgacagtgg
     1741 cacttgccat ccctctttat aaaaacttcc gtttactgaa agagaatttt tatcctgtaa
     1801 tggctgcgat tttagcagga atagtcgcaa attgcttggt tagtgtaggg ttcggttact
     1861 tcttctctct tcataaagag atggtgatct cattactacc taaatctgta acgacggcta
     1921 tttctgtcga tttatctcat acgatgggcg gggtgaatgc cgtgacactt gctattgttg
     1981 tctctacagg tatttttggt tcgctgatcg ccactcatat tttccgccta ttcaagatcg
     2041 aaagtccagt tgctcgcggt gtggcgttag gaagtacttc tcatgctatt ggtacagcaa
     2101 aagcaatcga gattggtgaa atagaaggaa tcatttccgg acttgcgata tgcgtcaacg
     2161 gaatattgac cgttttattg ctaccgttat tctttcagcc ttttgctggc ttgttttgat
     2221 gcgaaaacca ctattttatg ctacaataac caaaacgttc gagcataaaa aaggagggaa
     2281 agacgtgtat ttgtcttccg agtatcttaa acaatttgat aaagatctat attataagat
     2341 tctcctccta gaaagttttg aggatcaagc ttggcatacc gctgcacaat tagcgcaagt
     2401 tgttcagctg gatgcccgca gcgtgtcgaa atacctgaac gagctgtcta aaaactatca
     2461 gcagtttagc ggtaagacac accctttgtt tacaaaaaat caccgttctg gttataactt
     2521 ttatgatacg ctcgattcaa ttgaacatga gcgttttttg atctatctcg tgcaaagtac
     2581 gctgaaattc cagttgctgc acgacatttt ttttgaagaa ttccatacaa tgtaccaatt
     2641 tgcgcaaaag cattacatta gtgaatctac tgctcatcga aaaatcaatg aatggaaaca
     2701 gcaactgcaa acttacggaa ttcggctgca acgaggtaca tatatcgctc aaggcgaaga
     2761 agaaatcatt cgactttact tgcatatgac attctggcag ttgtttcgag ggaaaatctg
     2821 gccatttgaa acgatttctc aaatggacgt aaagaatatg gcagaacata tcatggcttt
     2881 ttttaatgtt cgtctgaacg agatcaaaaa aagacgattg gaatatatgc taggtgcctt
     2941 ttttttaaga aaatcacaga agcattatgt tgtattgaat gagaaaaaaa gacggctgat
     3001 ttctgacaat ctgttgttcc agcgattttg ccaggtcatg gagccggtat ttcctaatta
     3061 ttttcaagta gaagacgagt taggcgcatt atttcttgta ctgatgactc gtgaagaata
     3121 ttatagtgat cctaagatac ggaagaaaat ttttgatttt catcaacaag caaaaacacc
     3181 gccctttaca gccctttcag aagcaaaagc cgctctttct ctttatcagg aagagcaggg
     3241 gctgccagca gaaaatctaa ccttcgaggc agaaaactat ttattcagca gtcatttttt
     3301 cgcctatctt tttcctaatg cgaaagaaac gattgatggc aatagtagtg attttattaa
     3361 tcatttagtt attgaaaaca aggaattgaa acaatggctc gtacattttt ttgaaagtag
     3421 acacaaacat cccaatcatc tggcatttaa aaatcatgcg tttttgatgg ggcggtatct
     3481 gactgtgttt aaaacattag gagcctttac tccacagctt ccaaagatca cgatcctttt
     3541 aatgacagat ttcccattat ttgaagagca actgttagag gagggattac ggacattttt
     3601 ccgtaatgag tatcagctga tttttctgcc aacagattat cgggggagag aagttgatct
     3661 tctgatttcg acaagtaaag tccaccgcaa accatgggcg gatcttgact attttattgt
     3721 gactgaagaa ctaaaattaa ttgattacat ccaactatct caaaaatttg aaatgattca
     3781 aaaacaaaaa ctattaaaac aataacaaag aaggagaaaa aagatgacat ttgaagaaat
     3841 tttaccagaa ttgaaaaaag gtgcaaagat tattcgtaaa ggatggagtg gatttgaact
     3901 ttatgttgtt ctcgtatccg atgatgaatt tgatggctgt ccggtgacgc cgtacttatt
     3961 gatcaaaaca agtgacgaag gtttttccag cttcgctcct acagtttgtg atattttagc
     4021 agatgattgg gcgatcgtag aatgaaaaac cagtatccag atctagctaa acaggttgta
     4081 tttatcacag gagctgcttc tggaattggt gctgcgcaag cccgagcgtt tcttgaacaa
     4141 gatgcttttg tatttggatt agatcaaaag ttcggtaaaa tggaagaaat ttctttgcga
     4201 tttcctgaaa cttttgccta cgcactaggt gatgttcgac aaatgaaaga actccaacaa
     4261 gcggtatcga aatgccaaaa tcattttggt gaagttacga ttttactgaa tacagcgggg
     4321 atattggatg cctacaaacc cttgatggaa actgacgaat cgctgtggga tctgatttat
     4381 gagacgaatg tgaaaagcat gtatcagctg acaaaaatca tccttcctga tatgatccgc
     4441 caaaaaagcg gaacgatcat caatatggct tcgattgctg gcttgattgc tggtggaggt
     4501 gggatcgctt atacaagcgc gaaacatgcg attgtcggat ttaccaaaca actcgctctg
     4561 gattacgcag gacagggtat ccgagtaaaa ggaattgctc caggagccat ccaaacacca
     4621 atgaatgcgg ctgattttga agggaaaggt gagatggcag agtgggtggc aaatgaaaca
     4681 ccagtcaagc gatgggcaca gccggaagaa gtagctgagc tgacgttatt tcttgcctct
     4741 cctcaagcaa gctacataca aggaacgatc atcccaatcg acggcggatg gttgttaaaa
     4801 taaccttgtg tttttttcaa gcttctgtat gataaaacta aagagagaaa caacggttga
     4861 tgataaaaaa agtcgatgac tgttcccgac attcgatgcc gaacagccag ttcaaaaaat
     4921 tctttttaat aatcgttaat attcgaaact aagcggcttt tcacgacctc ttgatataaa
     4981 cgatattcaa aagcttgcaa ctgcggtaac aagtccagcc aaatgaaaaa tataaggagc
     5041 tatttttatt tgaccattct tattacttgt tgcagggcag ctttttcact accttctgcg
     5101 acacttcagt tggaattttc ttcccatcct ttggtcgcgg tcattaccaa gataaaatta
     5161 tcttgcaaag gagaaataga acatggaaaa aaataatacc cgttcagcca aacgctggac
     5221 aacgacagat gtgactcgga tggcgctagt cactggttta tatgtggcag tgacgctggt
     5281 tttgtctgtc tttagctttg gagtgattca gattcgtctc tcggagatgt tcaactatct
     5341 gtccttgtat aacaaaagat acatcgtcgc ggtaacagcg ggagtagctt tggctaatat
     5401 tgcttctcct cttggactga tagatgttgc agtaggaagc gtcagcacgc tgcttgtatt
     5461 gcttatcaac tataaaatca ctagtcgcat caaaaacatg aaaatcaaaa tggccgtgac
     5521 agcatgcgta tttgcttttt ccatgtttac agtagctggt cagctaacga ttttatatca
     5581 actacctttt ttcttgaatt ggtgggtgat tgctttagga gaattggcat caatgattgt
     5641 cggtgggata attatttatt ggatcggtaa aaaagtggat ttgtcaaaat aaagatctgt
     5701 ttaatttaaa atagggcagc atggaagaga ctgaatgttg agtcttcttc catgctgctt
     5761 ttttgattaa tttgtatgaa gaaatcgatt tagccgtttt ttcatcaaga taccgatata
     5821 agctgctcca gttgccttga ttgcttccgg cagtaaaaac ggcagtagtc cactggcaaa
     5881 tgcagttgta aaagtaagat caccacttat tttcagccag atcgttccgc agatcaatgc
     5941 agcaagagag cccattagat tggcaaagat tgcatataag taatgagcat ccgttctttc
     6001 gatcatccaa ccagttatcc acgtttgtaa gagaaatcca atcaaatatc cgccagttgg
     6061 cccaaataaa acagctatac ctccagtcat ccctgaaaat acaggaagac caatcaagcc
     6121 aagtaaaaga taaactccaa cagatatcaa tcctagtttt cttccgagaa aagttgctgt
     6181 taatccaata gcaaatgttt gccctgtcaa aggaaccaaa ccaaaaggaa tggtcatctg
     6241 agaaaggaca gaaataatcg cggcaaattc cgcagcaagt atcaattctt tcaatgttcg
     6301 gttcataacg ccctcttttc gttaacttaa tatttttatt tggttaacga aattgtaaaa
     6361 caaagtgatt actttgtaaa tagaaaatat aaaaaaagac cagctatcca atagatagcg
     6421 gtctttttca agaaagcttt tgaaattata agctttggtt gtagtattca acgacaagag
     6481 cttcgtcgat ttctggatat agttcgtcac gttctggtaa acgagtcaat gaaccttcca
     6541 atttttcagc gtcaaagctt acgaatgctg ggcgtccaac agttgcttct acagcttctt
     6601 ttactgttac gatgttttgt gatttttcac gaactgagat cacttgaccc acttctacgt
     6661 ggtatgaagg gatatcaacg cgtttgccat caactaaaat gtgaccatgg ttaactaatt
     6721 gacgtgcttg acgacgagtc gttgcaagtc ctaaacggta aacaacattg tctaaacgtt
     6781 gttctagtaa gatcatgaag ttaacaccat gtttaccttc tttgattttg ctagctttta
     6841 cgaacaagtt acggaattga cgttcgttca ttccgtacat gtgacgaagt ttttgttttt
     6901 cagttaattg catgccgtat tctgattgtt tgccacggct attaggtcca tgttgacctg
     6961 gtgcgtaagg gcgacgtgct aattcttttc ctgtgcctga caatgagatg cctaagcgac
     7021 gagaaatttt ccatgatggt cctgtataac gagacattaa aatttcctcc aatgaatata
     7081 agtttttgga gtaaaataat ccgttgaaaa attcataatc atatagtttg ttcttcaatc
     7141 ttcacctttg cagccgcggt tacacaatcg aacccgagac ggggcaacaa actagggatg
     7201 agttattatt tttctgctgc attattttac acaaattaca gtatatgata gatcatccac
     7261 gaatgtcaag ataattagta cataaaaacg ctttacaaac ctaggctgtc tttataaaat
     7321 gagagggtat gtgcaaatgg aaaaaagcga aggaagttta aggagaaaat caatgaatcc
     7381 ggtatcacca ttatttgaga aaatcgatgc ttcaattgaa aagaaggcga atctttttga
     7441 aaacagcttt tcacgttacg ctgttcgagc ggttctcgcc tgtttgtttt tgactttagg
     7501 aacggctgtg gcatttgcga tcgcgatgaa gggggaagat atcgcgcatg gtctaggaaa
     7561 gattttatac gcatttatgt tcagctgggg tctggtcatg attctataca tgaacgccga
     7621 attaggaaca tcgaatatgc tttatatgac cgtgggtgtt tttcggcaga gacttgcttt
     7681 aagtaaggca gccaagattc tatttgcctg tatttttttc aatatgattg gcggtatatt
     7741 atgtggattt ctaatttcta tgactacgcc atttcaagat ttaacgttgg acaactttat
     7801 gttagaatca atagcagtaa aactagcaaa accttcagca acgattttgg tggaagggat
     7861 gtttgcgaat atcgttgtca ataccgctgt actgatcagc atgcggatga aagaggatgt
     7921 cggaaaagtg atcacagtcg tattcatcat tttcattttt gcttttttag gatatgaaca
     7981 cgtgatagcg aattttcctg cctttacgct tacttacttt gcttctcacg gacagatgga
     8041 tggaatgaca gtcagcaatg tgttacataa tttgtttttt gctttggcag gaaattatat
     8101 tggtggcggt ttagtaatgg gactgggata tgcttggctg aatcagtcaa aatcatccta
     8161 tgtggactaa aaagtcgttc attaaagggg aagtgccatg gaagttttag tttttccaaa
     8221 aaatgaggaa aaagcgttac aaatggaaaa gtacatgaaa aatctttttt cctttgctgg
     8281 agtacctaag ccggaacgcg ctcttttaca acaaccgtta ctggatgaga gcaaaaattt
     8341 atctatttct gaagttttag cttttgttca ttattattat gaacaaatcg aaagagagta
     8401 tcagtatgta gcgatcgatt tagtccagaa aaacatcaaa cggcttacat ttgaagactt
     8461 agtcgtattg ttgccactag ttcagaaaaa agaatggtgg gacagcatcg actcttggag
     8521 aaaagtatac agcacatggt gtaaagccta cccagagcag cgtgaagaag tctttcaatt
     8581 gtttgaaaaa aaggaagatt tttggctacg tcgaatagca atcacgttgc aattaggtta
     8641 taaacagcaa acagacacag gactattgat ccgagcaata gacgaagatc gtcaaacaaa
     8701 ggaattcttt atccaaaaag caattggttg ggcattacgc gattatagta agaccgatgc
     8761 cgattgggta aaaagacagc tgacaacaga tttgagtaag ttagctgttc gagaggcaag
     8821 taagtattta taagaaagcg agacgacaag agatgagacg caaattattt gcttttgata
     8881 ttgatggaac gttgttagat tcaaacaaac aagctttaga tagcacaaga gaagcattgg
     8941 aaaaattacg caaagccggt catctggtca cgattgctac agggcggagc cgatttcatg
     9001 cgcaagagat cattcgcgat cttgatttta cgaactacat tttatgtaat ggagcggccg
     9061 gttttttaga ccatgaacaa gtatataaga atttactaga tcgcgaccag ttggatgcgt
     9121 tcgttcaaga agcgcatcat gagcagatcg atacagcttt tgtcagctta gacaatatca
     9181 agcgttcttc ttccaatgat gtaacggtga tggaagaagc gatgcattct ttcggtgctg
     9241 tcttgcctga attagatcag ttttttgcag aggaacaaga aatataccaa gcgttagcat
     9301 ttttcgatca aacatatgat gggaagttct cttcatatga taaaattcga tttgtccgct
     9361 ggcatgagaa cagtgtagat gtcgtaccta aaaatggttc taaagcagcg acaattctgc
     9421 acttagcaga acaagtaggc atccctcatg aagacatcat cagctttggc gatggacaaa
     9481 acgaccgtga aatgttgcgc atgtcaggaa ttgggatagc tatggggaat gctgtgccag
     9541 aagtacaagc agaagctaag atggtcactg atacaaacga tcaggatgga atttggaagg
     9601 cattgaaaga gttaagcgtg atttaaaaga ggttgtgaaa aagctgttct gcatcaagta
     9661 ataagcccag ccaaacaaaa atagctcctc ctatttttcg tttttctggg cttattaccg
     9721 cagatgcaag ctttcgaaca ccgtttaagg aagaggtcgt gacagaagtg gtcagtttca
     9781 agaaataaga agggatttac gaaaattgct tctcaaattt ttgtaaaatt acggcttatt
     9841 tctgaagaag tagatgaaac aacgtttatt cgggaaatgg gactgtgaca agatgtttgt
     9901 catagtccca tttttttatt ttatttttca aaactaagaa ataccaggaa agagttcctt
     9961 ttgtttgacc ttttctttct tattgaaaac aactataata tagagtgatg ttaaaagaga
    10021 agaggaattt agtgtgcggg tattgtttat tggtgatgta gtaggttcaa tgggacgaga
    10081 gatgattact gaatatcttc ctagattgaa gaagaagtac cgtccgcaag taacgattgt
    10141 aaatggtgag aatgccgctt ctggacgtgg aatcacagaa aaaatctata aaaaattttt
    10201 gcaagacggc gtagatgtcg tgacgatggg gaatcatacg tgggacaacc gcggaatctt
    10261 tgagtttgta aatgaagcta aaaagatggt tcgtccggca aattttccgg aagggacgcc
    10321 tggacaaggg atggtctttg tcaaagtgaa ccaagtcgaa ctggcagtga tcaacatgca
    10381 ggctcgttct tttatggtgg acttggatga tccttttcgt aaaatgaatg agctggtaga
    10441 agaagccaga aaacgtacgc cgatcatttt tgtagatttt catggagaaa caacaagtga
    10501 aaaacaagca atgggctggt ttttagatgg gaaagtttca gcagtggtcg gtacacatac
    10561 acacgttcag acaaatgatg cgcgaatttt gccaagagga acagcgtatc tgacagacgt
    10621 tgggatgaca ggtccctatg atggtatttt gggtatgcgc agagaacctg taatcgaaaa
    10681 gtttctgact gcattaccaa aacgttttga agttgtggaa caaggccgat cgattttaag
    10741 cggctgtatc ttggaattgg atgatacgac aggtcatgca aaagaaatcc agctgattca
    10801 gatcaacgat gatcgaccgt tcatggagta gaaagagagg cagttttttg cagcaggagc
    10861 cggaaattca aaaagaagta aggaaactga caaaactttt aagagagaat gaaacgatca
    10921 ttcgctacaa agaacttgaa gaaaagatcc agcaaaacca gtatttagct gagttgagag
    10981 aaaaaatcaa acaagcgcaa aaagatgctg ttcattttgc ccactatgac aaaccagcag
    11041 cagaaaaaga agcaatcaaa caagcggatc aattcatgca agaatttgat cagcatccgc
    11101 ttgttgtagc ttatagaaaa cagctgttgg aagcagatga tctgcttcat catttaacaa
    11161 ctatgataca agaagaaatc aatggacaaa tagaggagga aaaacatgcc tcaaaaaact
    11221 aaaaatactc ctatgatgga acaatatcta agcatcaagg cccaatacca agatgctttt
    11281 ttgttctatc gtttaggaga cttttatgaa ctattttacg aagatgcgat caaagcgtca
    11341 cagcttttgg aattaacgtt gacgagcaga aatcgaaatg cagaagaacc tattcctatg
    11401 tgcggtgtac ctcaccatgc agcacaagga tatatcgatg ccttgattga aaaaggctat
    11461 aaagtagcga tttgcgagca ggtagaagat ccaaagacga ctaaagggat ggtcaagcgc
    11521 gaagtgatcc agctagtcac tcctggtaca gtcatggaca gcaaaggatt gtcggcaaaa
    11581 gacaacaatt ttttaacagc tgtagttagt caaggaaatg aatttggctt tgcttatgcc
    11641 gatttaagta cgggagaatt gaagacggct cggttgcatg atgaagaagc tgttttaaat
    11701 gaagcctctg cattgcagac aaaagaactc gtattaggca gtgagatcac tgataccctt
    11761 cgtgaacagc taagcgggcg tttagggcta gtcttttctc aacaaaatga gatggaagaa
    11821 aacgcggaat ttagcttttt gacaagcgaa ctagtcgatc cgctggaaaa agaagcaacc
    11881 ggcaaactat tgacttattt atcggtgaca caaaagcgga gtttagctca tatccaaaaa
    11941 gcagtagaat accaaccaga tcattttttg aaaatggatt attattcaaa attcaaccta
    12001 gaattaagcc aatctattcg gactgggaaa aagcacggca ctcttctatg gttgttagat
    12061 gaaacaaaaa cagcaatggg tggccgttta ctaaaacaat ggctagaccg tccgcttatc
    12121 caggcaaaac aaattaaagc aagacaagaa atggtcgctt ctttgctaga cagctatttt
    12181 gaacgtatcg atttgcagtc agcattaacg aaagtctatg atctggaacg cctagcaggt
    12241 cgagtagctt tcggtaatgt caatgggcga gacttgatcc agctgaaaac ttctttagaa
    12301 caagtgccaa tgatcagagg gttgattgaa ggaatcgatc aaggtcaatg gcaaagtctg
    12361 ctttcagaaa tgcagccgat ggaccatctc gtccaattga tcgaccaagc tatccaagat
    12421 gatccgccgt tacaaataac ggaaggaaac atcatcaaag atggattcaa tgagcagctc
    12481 gatatgtacc gttctgctat gagaaacgga aagaaatggt tggcagaact tgaagcaaaa
    12541 gagcgtcaag aaacaggaat caagaactta aaaatcggat ttaaccgcgt tttcggttat
    12601 tatatagaaa ttacaaaagc aaatcttgga aatgcagaac tggagaagta tgaacgaaaa
    12661 caaactttag caaatgcaga gcgtttcatc acaccagaac taaaagaatt ggagacacaa
    12721 atcctcgaag cagaagaaaa atctgttgat ttagaatatc agttgttttt agctgtgaga
    12781 gaagaagtca aaaaggctat ccagccgcta caagtacttg caaaagcaat cagtgcagta
    12841 gatgtgctac aaagttttgc aacgatcagc gaacgctatc agtatgttcg gccagaactt
    12901 gtcagtgaca agcatcagct tctgatcaaa gacggacgac atcctgtagt agaaaaagta
    12961 ttaggacatc aggaatatat ccctaacagc gtagaaatgg cagaagacga aatgatcttg
    13021 ctgattacag gaccgaatat gtctggtaaa agtacgtata tgcgacagtt ggcattaact
    13081 gttctgatgg cgcaaatggg ctgtttcgtt ccggcaaaac aagcagtttt acctattttt
    13141 gatcggattt ttacccgaat tggtgcaagt gacgacttaa ttgctggaca aagtactttt
    13201 atggtagaga tgatggaagc caatcaagcc ctgcgttatg ctacgccaaa cagtttgatt
    13261 ttgtttgacg aactagggcg aggaacagca acctatgacg gaatggcgtt ggcccaagca
    13321 atcatcgaat atatccatcg tcatgtacaa gcaaaaacac tcttttctac tcattatcat
    13381 gaactgacgg tacttgagaa agaacttccg cagcttaaaa atgtccatgt tggagccgtt
    13441 gaaaaagacg gagaagttgt cttcttgcat aaaatgatgg atggacctgc ggataaaagc
    13501 tacggcatac atgtggcaaa gatcgcagga ttgccttcca atctactaga acgagcagca
    13561 gatatcctgc atacgctaga aaatggcgat aacggacacc atactgttcc agctgaagta
    13621 gaagagaaaa ctaaaacagc caaacaggag caaataaaac cacctgcaga aaaagtaaat
    13681 caagaccata tacaagaccg tgtaaaagaa gaaaaccaac agctttcttt attcagtgaa
    13741 ttatccgaaa atgaaacaga agtcattgaa tcactgaagc aaataaattt actagaaatg
    13801 acgccaatgg atgcactaaa cacattatat gaattacaaa aacaactgta ggaagaaggc
    13861 ggatatcgat ggccaaaatc caagaattat ctgaacgttt agctaatcag atcgctgcgg
    13921 gagaagtagt ggagcgacca gcttccgttg tgaaagaatt agtggaaaat gcaattgacg
    13981 ccggcagtac tcagattgat atcttagttg aagaagcggg actgcggacg atccaagtga
    14041 ttgataacgg agaaggcatt ttggcagacg acgtagagaa tgccttcaag cggcatgcga
    14101 caagtaagat ccataatcgc gacgatcttt ttcgcatacg aacgctgggc tttcgagggg
    14161 aagctttgcc aagtattgcc tctgtttctg aaatgactct ggaaacggcg aatcaggaag
    14221 aaaaacaagg cacctatctg tcgctgaaag gcggagaagt tattgagcat cgaccagcac
    14281 cactgcgtca aggaacgaag attaccgtca gcaatctgtt tttcaatacg ccagcccgct
    14341 tgaaatacgt gaaaacactg cacacagaat tagcgaacat cggggacatc gtcaatcgac
    14401 tggcattgag tcatccatcg attgcttttc gtttagtaca tgatggaaac aaaatgctgg
    14461 caactgctgg aaatggcgat ctgaaacaaa caattgcggg aatctacgga ttatctaccg
    14521 caaaaaaaat gctgaaaatc gaaggaaaag atctagattt tgagttattt ggctatgttt
    14581 cattgcctga ggtgactcgt gccagtagga attacttatc gacgatcatc aatggacgtt
    14641 ttatcaagaa cttttccttg aataaagcaa tcgttgcagg ttatgggtca aaattaatgg
    14701 tcggtcgttt ccctattgct gtattggaaa tcaaaatgga cccgctttta gtagatgtaa
    14761 atgttcatcc gacgaagcag gaagtccggc tgtcgaagga aaaagaacta acagagctaa
    14821 ttagtaacgc cattcaaaaa gcattgtctc aagaaaatct gattccaagt gcagcggata
    14881 atctacggtt taagaaaaaa gtacctgatc agcctaaaac agaacaaatc gaaatcgatt
    14941 tgtcctacgc ttttgaagaa gaaaaaccta aaaagccaag tagtttgaat tttgatcgac
    15001 agacaggtac ctttttcgta gaagaactaa agaacacatt tgttgacaga attgttgata
    15061 agtctgtgga aaatgttgaa aactattctg gtttttctga agaaaacacc acttatccag
    15121 aaaaaacagc gaaaacggtg gataagtttg gtgaaaatgt tgataacttt gtagaaaaaa
    15181 cagtggaaaa atctgaaaag aaagaatttc ccattgtgga taacatggag aaaacaaatg
    15241 aagaacaagc agataaatcc gtagaagagg atgaaaagat ttacgaggaa gaattgacac
    15301 tccatcctga atttgatttc actcaaggaa acgacaaaac attagaacaa gccatcaaga
    15361 aattagaaac ggaaaaacca gtacaacgtt ttcctcagtt ggaatatttt ggacagatgc
    15421 acggaacgta tctttttgcc caaagtagcg atgggttgta catcattgat cagcatgctg
    15481 cccaagagcg cattaagtat gaatatttcc gggaaaaaat tggggaagta tctgatgatc
    15541 tgcaagaatt gcttgttcca tttgtgttag actatccaaa cagtgatgct ttgaaattaa
    15601 aagagcaaaa acacttgcta gaagatgcag ggatttattt agaagaattt ggtcaaaaca
    15661 gctttattgt acgggcccat cctacttggt atcccaatgg agaagaagaa tcgattattc
    15721 gggagatgat cgatatgctg ctgacaactg gaagtgtgag tgtaaaaaaa ttccgtgaag
    15781 caacagcaat catgatgagt tgcaaacgat cgattaaagc caaccattat ttgaatgaag
    15841 cacaagcacg tgtgctgctg aaggatctgg cacgatgcga aaatcctttc aattgtcccc
    15901 atggccgtcc agtattgatt cactttacca attcggatat ggaaaggatg ttcaaacgaa
    15961 tccaagaccc gcattaagtc aaagagaaga gggaaaacat gaagattgta ttagcatccc
    16021 aatcaccaag aagaaaagag ttattggctc atatcgtttc agaattcgag attgaacctg
    16081 ctgatatcga tgaaacgcca tttccagacg aacagcccgt cgattatgtt cgtagaatgg
    16141 ctgaagaaaa agcacgaact gtctgggaac aagatgaaaa agaagaccat ttagtgattg
    16201 ccagtgacac gactgttgtt ctcaatcaag agatcatggg taaaccagaa gatctggctg
    16261 aggctgaatt catgctgaaa aaactaagcg gggaaacaca tactgtatat acagctgttg
    16321 ttttaaaaac aaaggaacga gaagaacgga tactagcaga agcacatgtc actttttatc
    16381 ctttgacaga cgaagagatc aaacgctact tggagacggg ggattatgcg gataaggcag
    16441 gggcatacgg catccaaaat gctgcgagtg tattcgtcaa agaaatttct ggagattatt
    16501 acagtatcgt aggatttccg attggtgctg tcaatcaggc actgaaaaca ttcatttaaa
    16561 caaaaaagcg gactatctga ttttcgattg aaaatccatg atagcccgtt ttttttattg
    16621 aaaagattac ttatctactc tgactaagat tttacttcag ctttaccgac tgcttcgccc
    16681 gggcgaacaa gtcctgattg gtcaagagaa agtcctgcaa ctttttcatt attggtcaaa
    16741 gcaacaataa tgtcagtttt cttgccagct tgttctattt ctggcaaatc catttcagca
    16801 atcagggtct ctggtgtgac aaggtatcct tctttcacga atacattgaa aggaacaccc
    16861 tttagttcaa cagtatctaa tcccatgtga acaagtactt ccagcccctc attagaaaga
    16921 ataccaatgg catgttttgt ttcaaagaca ctcgtcactt taccgtttac tggtgcatag
    16981 actttgccgt ttgacggttc gacagcataa ccgtcaccca tcattttttg tgagaaaact
    17041 gggtcattta cttcagttat ttccttgatg gtccctgcag cgactgcgaa taatgtttct
    17101 tttgttgcaa ctgccgtacc agttgctgaa acaggttcga aagactgtgg cgttgctgtt
    17161 gcgccatttg ctgtttgaag ttgtacatca gcagcatttt caggaacagc aggatcaatc
    17221 ttattcaaaa ttccctgacg tctaaagatg atcgtcaagc caaatggaat gatgacagca
    17281 atgatcattg cgatgatgaa aggtacccat gtttctgctt ggatagctag tattcctggc
    17341 aaaccgccta ctccgatcgc gttagctcga acacccatca agttagcaaa catgccagct
    17401 aatccagagc cgaccattgc agcgacgaaa ggatagacgt atttcaaatt gattccgaac
    17461 atagcaggtt cagttacgcc taagtaacaa gaaatcattg ctggaatcga gatttgttct
    17521 tcttttttat tcccacgatg taagaagatg atggctaaga ctgcagagcc ttgggcgata
    17581 tttgataaag caatcatcgg ccataaattc gttgatccga aatctgcaat cagctgcata
    17641 tcgatggcat tggtcatatg gtggagacca gtaatcacta aaggagcata caggaatccg
    17701 aatacggcac taaacaacca gctgatagaa gacgtcaatc cagtatttac gatatttgag
    17761 atccagcttc cgactgtcca gccgatagga cctaaaataa cgtgtgcagc taaaacagtt
    17821 ggtaacaatg aaaacaatgg aacaaaaatc atcgagatcg actgagggat atatttgcgg
    17881 aagaagattt ctagatacgc taacataaac cctgccagca tggctggaat aacttgcgct
    17941 tgataaccaa tcatctggac ttgagcaaaa ccaaaatccc aaaatggaat atctgctgcg
    18001 gctgtggaag ctacactata agcatttaat aattgcggag aaactaacgt aattcctaaa
    18061 acgattccta atatttgtgt agtacccatc ttttttgcaa tactccaagt gatacctact
    18121 ggaagaaaat ggaaaattgc ttcaccgggt aaccacaaaa aggcattgac accattccaa
    18181 aacttcgagt gttcaacgat tgttccacca agactttcaa actggatacc ttcaagtaca
    18241 tttctgaatc caaggatcaa tccaccgaca atgattgcag gaatcagtgg tgtaaagatt
    18301 tctgctaaaa cggcaatagc acgttgaacg ggatgaaggt tttgttttgc agctgctttt
    18361 ccttgttctt tggaaacccc ttcaactcca gatactgcaa cgaagtcgtt ataaaaagta
    18421 gaaacatcgt ttcctatgat gacttggaac tgtcctgcat tcgtgaacat cccttttacg
    18481 ctaggtatat cttcgatcgc tttttcgtcc gcttttcctg gatcattcag gacaaaacgc
    18541 atacgagtcg cacaatgact aactgcagca atattttctt ttccgccgat atcatgtaac
    18601 agcttctcgg catctgcttg atattttgcc atatcaataa acccctttct cttaacttgt
    18661 ctatgcaagt tgtttcttca tttactatac tttttttcgg agagaattgc aagcgtttta
    18721 ttaaaaagta cgagagaaaa tgatatcgtt ttaaaaagct taaaataagc ttttcttaaa
    18781 aataggaaca ttgaaataca aaaagagctg tagtatagtg aagaaatgat ggaagaacga
    18841 gtgagggaaa aaacatgaat aagttcaatg aaattttttt agatttggaa cagaaaattt
    18901 tagcgaaaga atatcctccg cattcgcttt tacccagtga gaaccaattg atcaaaattt
    18961 atggtgtttc acgagaaaca attagaaaag cgctgaatct tttgactacg gaaggttata
    19021 ttcaaaaaaa acaaggaaaa ggttcgatcg tactggatcg gaatcgcttc gactttccta
    19081 tttctggatt gactagctat aaagagctac aggagaccca acgtattcca agtgaaacga
    19141 tcatccatac gttagaagaa acagaagtga caaaagcatt gaacgagatc actggctggg
    19201 agatcggtgc gcctgtttgg catttgatac gcgaaagaaa aatcaatggc gaagtagtta
    19261 tattagacac cgattatcta ttaaaggaaa tcgttcctat tttaactcca gcacaagcac
    19321 aaggatcgat ctatgaatat tttgaaaatg agctttcttt gacgattgct tacgcgcaaa
    19381 aggagatcac agtagaagaa gtaacggaaa tcatgaaaac agcgatggat cttcacgatg
    19441 acacttatgc agtagtagtc agaagcctcg ttcatctgga agatacccgc tgtttcgagt
    19501 attctgagtc ggttcaccga ttagataaat tccgtttcgt tgagtttgcc cgacgccgaa
    19561 aagtgtaaat agttcaaaag aaagcaaatt gttggcatct gtccactttg gcgctatgat
    19621 aggatcacaa agggggcatt tttaatggat aaaccaataa gaccagaaaa agaagaactg
    19681 aaagaaaagt tatcacccat ggcttatgca gtcacacaag aaaatgcaac agaacgacca
    19741 tttagcggga aatatgatga tttttacgaa aaggggatct atgtagatat cgtcagcggt
    19801 gaaccgttat tcagctctgc agaaaaatat gatgcaggtt gtggctggcc atcattcagc
    19861 aaaccaataa cgaaaagaca agtgcgcgaa aaagccgatt tttctcatgg catgcatcga
    19921 atagaagttc gaagcaaaga agcagattct catctcggac atgtgtttac cgatggacca
    19981 gtagatcaag gtggtctacg ttactgcatc aattctgcct cactgaaatt cattccatat
    20041 gaaaagatgg atgaattagg ttatggggaa ttcaaatcac ttgtagaata atggaaatac
    20101 acaaagagcg gtacaatacg gggatttact cgatcgtccg ctcttttttt attcaagcga
    20161 ttgctatttg aaagaaacgc tccctagact cctttttttc acaaggtgaa atgtgctaca
    20221 ataaagggaa cgtatgtgtg caaaagaaag aggactagaa tatgtatgaa tatctgacag
    20281 gtgtggttac ctttatcaac ccctattaca tagtagtaga aaccaatggt atcggctacc
    20341 agatcgcact aggaaatcct taccgctaca gtagcaaact aaatcaaaaa ataaaaattt
    20401 atgtccatca ggtaatacgt gaagatgcgc atcttctgta tggatttgat tcgctagaag
    20461 aaaagcaact gtttttgcga ttagtaagtg tttcaggaat cggtccgaaa agtgcccttg
    20521 caatcatggc aagcgaagac cactccggtt tgattcaagc agtagaatcc agtgatgtca
    20581 cttatttgac gaaatttcca ggagtaggga aaaagacagc acaacaaatg atcttggatc
    20641 taaaaggaaa attcggtgag ctgagtatcg atacaccttt tagtctattt gatgaagcaa
    20701 acacaaaaga cgctacagct ctatctgaag caatggaagc tctctcggct cttggttaca
    20761 gtgatcgaga aatcaaacgt gtagaaaaac aattaaaaga agtagataat cagacaacgg
    20821 atgagtatct acgccaagca ctcaagctaa tgatgaaaaa ataaggagga gaccaaatga
    20881 cagatgaata cttgttatca ccagaatctg gcgaaaatga actgagtttg gaaaaatctc
    20941 ttcgaccaca gctgctttct caatatatcg gacagagaaa agtcaaacaa gaacttcaga
    21001 tttacatcga agctgccaga aatcgggaag aacctttaga tcatgttctg ttgtacgggc
    21061 ctcctggatt aggaaaaacg acgatggcca tggtcattgc taatgagatg accgtaaata
    21121 ttcgtacgac gagtggccct gctatcgaac gtccgggtga cttagtagca atcttgaatg
    21181 aactggaagc aggggatgtc ctgtttatcg atgagatcca tcgattacct agagtggtag
    21241 aagagatgct ttattcagct atggaagatt tctatgtaga tatcatggta ggacaagggc
    21301 caaccgcaca tccggttcat ttccctcttc ctccctttac tttgattggc gcgacgacac
    21361 gggcaggtat gctttctgca cctttacgag atcgatttgg catcatttct catatggaat
    21421 attatgacga acaggatctg caggagatcg ttttacgttc ttcggatatt tttcaaacag
    21481 agatcattga agaaggggca ttggaaattg ctcgccgatc acgaggaacg cctagaatcg
    21541 ctaatcgctt gctcaaacgg gttcgtgatt ttgcgcaagt ccaaggagac gggaaaatcg
    21601 atcgtcctat agcggatcag gcacttactt tgctacaggt cgatcaggct ggattggatt
    21661 atgttgacca gaaattgttg cgaacaatga tcgagttata tggcggcgga ccagtagggt
    21721 taagtacgct ttcagtaaac ataggagaag agcgtgagac ggtagaagat atgtatgaac
    21781 cgtatctgat ccaaaaagga tttttaaagc gtacacctag agggcgaatt gctactgctt
    21841 atgcctatga acattttggt tacgactatc atatatgatt tttgctttta gattggagga
    21901 aaatgaatga gtgatacaac acgtacgaaa caattgatca aaaacgtatt gattgatttg
    21961 tgccaaacgc aatcttttcg aaaaatcagc gtccaaaaaa tcgcaaacga agcaaaaatc
    22021 aatcgacaaa cattttatta tcattttaca gataaatacg atttgcttcg ttgggtctat
    22081 tgtgaggatg cattgcatta tttagatcca caatgtcttt cacttgataa ttgggaagag
    22141 caagcattga aaatgctgaa agcaattgct gagaagaaag aattttatgc aaatactgtg
    22201 ctttctgacc cagaaatttt acaaaaagag ttttctcaac tgatccaaaa atcatttatc
    22261 aagatttttg aacaaatgga tgaagaaaga caactttctg caagagacaa actattttat
    22321 gctcgttttt tttcttacgg ttgcagtggt gtattagtca attggatcac gaatgaatat
    22381 gaagaaacac cgatggaaat cgctatgcag cttttccgtt tagccaagga tacggaatta
    22441 tattcttatc gtctttatgc aaaagaagag ttggaagaac agtaatagaa aaattttttg
    22501 ttggaaaagc aataatcgct aaaaggagat ggggaaatga caaaaatttt atttgtttgt
    22561 ttgggaaata tttgccgttc accgatggca gaaggcttgc tgagaaaacg aatagcatta
    22621 gaaggaaggg aagcagaatt ttttgtggat tctgctgcta caagcacgta tgaagttgga
    22681 aagacaccgc accctggaac gaaaaaaata ttaaaccaag aaaaagtaga tatgacgaat
    22741 atggttgctc ggcaaatcac accccacgat tttgaaactt ttgattggat cattggcatg
    22801 gatcaagaaa atgtagaaga actgaaacga agagcaccac gctcagcgca ggggaaaatc
    22861 catttgtttt taagtagcat tcctggaaaa gaaaaagaaa atgttcccga cccatactat
    22921 accaataact ttgatgagac atatcacttg atcacagaag gcctgaatca ttggtggaat
    22981 atttggattg atgaaaataa aataacaaac aatttgtaaa gttaacgctt tctttttaag
    23041 gcgatgttag agcatttcct tgtttttttg taaaatgtta ggtaaaataa aattaattaa
    23101 gtaacacttt cttagctaaa ggaggagtgc attcgatgaa cgaagagaca gtatcgccaa
    23161 tgaagaagct tacgaagtta gttactcata cttcgtatca actttttgat tcttttgtaa
    23221 atgacactga agaacatgct aagaatgtac gattgcaagg aaagtttatt cttgagctgc
    23281 aaaaagctgc tactgaacat agtctagtta tcttacaagt aagagcaaat cgtttgagta
    23341 gcaagtatga aacgatctca ggctgggtgg cgacaaaaac ggtcgaaaaa gaccgagtga
    23401 tgatccgcct acaaaacgaa gagcagcaga tccggatggt tcctgtagaa caaattgaaa
    23461 aaataacaat cctttcacca gcaggggaac aggaacggtt atcaaaataa tttataccag
    23521 atagaaaagc acgtatgagc ttgtaccatc aatcattact aatcaaaaat aaccgaatgc
    23581 tttaagctga tatcagtaaa acggaacgtt ttaggatgag tatcatagca tgacagcatt
    23641 cggttgatta gttgaatcga ttggatggta caagtttttt tgataaaaaa aggtcctgct
    23701 agccggggag ctagcaggat aaggagttaa aaatgaaaaa gtgttgttag ggttgtttgt
    23761 tggtatgctt atataatagt cattagttgt gaatattttg tgacgaaagt tttcgaaagt
    23821 tgttaagttt
//
LOCUS       DAZUJR010000043        23772 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.043, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000043 DAZUJR010000000
VERSION     DAZUJR010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23772
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.043"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            928..1254
                     /locus_tag="ACG804_001603"
     CDS             928..1254
                     /locus_tag="ACG804_001603"
                     /inference="COORDINATES: protein motif:HMM:NF013698.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFS4832539.1"
                     /translation="MFKIFRKNCCGLDVHKTWIYACIGITDANGRTVYKQARFSSFTK
                     GLNELAEWLAKYNCKDVCLESSGKFWIPVFNILEKTCFVTLAHPKYTKPQKGNKTDRK
                     DAKMDL"
     gene            1262..2170
                     /locus_tag="ACG804_001604"
     CDS             1262..2170
                     /locus_tag="ACG804_001604"
                     /inference="COORDINATES: protein motif:HMM:NF033542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFS4832540.1"
                     /translation="MCDMIKPSFIPGLEIRQLRDLMRYRTKLTNMKTSEKNRALNCLT
                     VSNLKLDDVFSDVFGKSSTSIIQYLLEHPGESFDVRPFIHARCKTPVEEIQAAVEGAI
                     SVPQAIKLRQCLNHINEIEKHREEINLEIQALAEPFSPVLELLRTIPGLDTQPITAIA
                     ILSEIGPDMSVFPTSKHFISWAGCCPRNDRSARRTKSTRISRAGQSLKPLLVQIANAL
                     LRSKEHPEFKNRYRRIKANRGHKKAIIAICKMLLTAIWNVLSKVEPYSAKGYLEPKPA
                     KEEKVLTQSQALDLLRKRGYTIIDSA"
     gene            2796..3050
                     /locus_tag="ACG804_001605"
     CDS             2796..3050
                     /locus_tag="ACG804_001605"
                     /inference="COORDINATES: protein motif:HMM:NF013224.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC ligand binding domain-containing
                     protein"
                     /protein_id="HFS4832541.1"
                     /translation="MIKSNQKSGFYTFIKAISSVLECDCIIGPYSMLIKMGFPSTESL
                     DSFINDLSKFGRTNTQIVFSTLVSLMVYQFWNVYHALLLK"
     gene            3592..3750
                     /locus_tag="ACG804_001606"
     CDS             3592..3750
                     /locus_tag="ACG804_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4832542.1"
                     /translation="MNKKQACEFLGIDNNTLDKWIRVYNFPVIKIDGVVRFDVEDIKD
                     FMNTFKKN"
     gene            3822..5048
                     /locus_tag="ACG804_001607"
     CDS             3822..5048
                     /locus_tag="ACG804_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4832543.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFREITGIASEKYQKVFPTRQLAIKA
                     EREMKKKIETVLREENANSLELKGKIKFKDFYESKWLPRYELGQTTRSNRAPSNVTIS
                     NTKDIFRLHILPMFGEYAMNYLNSNTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILCYIEFNRTTKIIQCITAPKKMALEEKRIREGNQALSSEELTDWIEAVNNDLNNHLL
                     TLHDYTLFMLTLYLGDRKSETYALQWKYIDFNKNTVRLKYALDKYQRKTHTKGWKDTV
                     IQAPEVVMTLLREWKSAQAEQLLKLKIIQTPDQYLFTYSKPSGEVNCPVHADYLNYRI
                     NAIKKRHPELAQLSPHKLRHTYATIAREGGANMNQISNALTHSDISTTKIYVNTPDVV
                     DKSVFEAFQKGLNKCD"
     gene            complement(5137..5529)
                     /gene="rpsI"
                     /locus_tag="ACG804_001608"
     CDS             complement(5137..5529)
                     /gene="rpsI"
                     /locus_tag="ACG804_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFS4832544.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(5545..5973)
                     /gene="rplM"
                     /locus_tag="ACG804_001609"
     CDS             complement(5545..5973)
                     /gene="rplM"
                     /locus_tag="ACG804_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HFS4832545.1"
                     /translation="MAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPTFTPHL
                     DTGDFVIVINADKVKLAGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLIETSVK
                     GMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(6507..6974)
                     /locus_tag="ACG804_001610"
     CDS             complement(6507..6974)
                     /locus_tag="ACG804_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HFS4832546.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(7094..8632)
                     /locus_tag="ACG804_001611"
     CDS             complement(7094..8632)
                     /locus_tag="ACG804_001611"
                     /EC_number="2.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046316 - gluconokinase activity [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0046177 - D-gluconate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HFS4832547.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            8712..9398
                     /locus_tag="ACG804_001612"
     CDS             8712..9398
                     /locus_tag="ACG804_001612"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HFS4832548.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(9599..10126)
                     /gene="msrA"
                     /locus_tag="ACG804_001613"
     CDS             complement(9599..10126)
                     /gene="msrA"
                     /locus_tag="ACG804_001613"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFS4832549.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(10210..10887)
                     /gene="pgmB"
                     /locus_tag="ACG804_001614"
     CDS             complement(10210..10887)
                     /gene="pgmB"
                     /locus_tag="ACG804_001614"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFS4832550.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(10884..12012)
                     /locus_tag="ACG804_001615"
                     /pseudo
     CDS             complement(10884..12012)
                     /locus_tag="ACG804_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
     gene            complement(12012..14195)
                     /locus_tag="ACG804_001616"
     CDS             complement(12012..14195)
                     /locus_tag="ACG804_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 65 protein"
                     /protein_id="HFS4832551.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(14192..15217)
                     /locus_tag="ACG804_001617"
     CDS             complement(14192..15217)
                     /locus_tag="ACG804_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFS4832552.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTANRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(15262..16089)
                     /locus_tag="ACG804_001618"
     CDS             complement(15262..16089)
                     /locus_tag="ACG804_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFS4832553.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(16086..17153)
                     /locus_tag="ACG804_001619"
     CDS             complement(16086..17153)
                     /locus_tag="ACG804_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HFS4832554.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(17179..18015)
                     /locus_tag="ACG804_001620"
     CDS             complement(17179..18015)
                     /locus_tag="ACG804_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4832555.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(18012..18881)
                     /locus_tag="ACG804_001621"
     CDS             complement(18012..18881)
                     /locus_tag="ACG804_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4832556.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(18951..20234)
                     /locus_tag="ACG804_001622"
     CDS             complement(18951..20234)
                     /locus_tag="ACG804_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFS4832557.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(20248..21933)
                     /locus_tag="ACG804_001623"
     CDS             complement(20248..21933)
                     /locus_tag="ACG804_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HFS4832558.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            22208..23233
                     /locus_tag="ACG804_001624"
     CDS             22208..23233
                     /locus_tag="ACG804_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4832559.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
BASE COUNT         6915 a         4950 c         4285 g         7622 t
ORIGIN      
        1 aaaaaaaata ggttttttat taaaactatc ttgacctttc gggagatttc actgtgattt
       61 atttttattc ccatactttt ttcgttggtc actttcgtat acctaatcta agcgatcatc
      121 ggcgacggtg cttttacaac gaatggcagg acaaaacaag gggcggaaaa acttttttgc
      181 ctatttcata aaaaactttt tcctacagca atcccttgtt ttgtcctacc acacgttgtg
      241 aacccaaagc acgccgacga acgcttagct atacgaaaat gacctccaaa aacaaaaaag
      301 tgaggtgaat agaaacaaaa agaaattgaa atctcccaaa atgtcgtccg cctcggagac
      361 aacttgctgc tgaaaatggt tggttaattc atttaagtat taaataagat aaatcatcaa
      421 attaatcgga aaaatagcat gattggcctt atcaaaaata aactgtaaaa acttatattt
      481 ctatgagtgg tggaacaatg ctaataccaa attaatttat cgattaccca cctgcacaaa
      541 ccaaagatag cattattagg aaacgaatca atcagcgaat ccagcattat aatgaggata
      601 ctaaaaataa agttttcata attataaatc cgccttccta cgaaaggcac caatgaggtg
      661 atgaaaacct tagagcgctt tctttctttt tttattccgt gttacccttt ccttgcaggt
      721 ccctggtaca ctacagaacc cgaggaggtg agtggcgggg ctgtatagcg gcaaccccgc
      781 ataattatat ggtgtcggtc atccgttaag gcatcaatga atggcgcaaa cccgtagccc
      841 gtaaacttat ctcttccgaa gttgactcga tttcgccgga tgaccagtcc ctaccaaacc
      901 tgtactattt ttttacagga ggttgctatg ttcaaaatct ttcgtaaaaa ttgttgtggc
      961 ttggatgtcc acaaaacgtg gatctatgcg tgtatcggaa tcacagatgc gaatggtcgt
     1021 acagtgtata agcaagctcg cttctcttcc tttacaaaag gtctcaatga attagctgaa
     1081 tggcttgcta aatacaactg taaggatgtg tgtttggaat cttccggtaa attttggatt
     1141 cctgttttta atattcttga aaaaacttgt tttgtcacac tggctcatcc gaagtacacc
     1201 aaaccccaga aaggaaataa aacagatcgc aaagatgcaa aaatggattt gtgatctctt
     1261 tatgtgcgac atgatcaaac ccagttttat tcctggtctt gaaatccgcc agcttcgtga
     1321 tctaatgcgt tatcggacga aactgaccaa catgaaaaca agtgaaaaga atcgtgcttt
     1381 aaactgctta accgtttcta atctgaaact agatgatgtt tttagtgatg tgttcggaaa
     1441 atcatccact tctatcatcc aatacttgtt agaacatccc ggtgaatcat ttgatgttcg
     1501 accatttatc catgcccgtt gtaaaactcc cgttgaagaa atccaagcgg cagttgaggg
     1561 ggcgatttct gtacctcaag cgattaagct tcgccaatgc ctcaaccata ttaacgagat
     1621 tgagaagcat cgagaagaga tcaatctaga gattcaagct cttgcagaac ccttctcccc
     1681 tgttttggaa ctacttcgta ccataccggg cttagacact cagccaataa cagcgattgc
     1741 gattctttca gaaataggac cggatatgtc cgtgtttcca acttcgaaac actttatttc
     1801 ttgggctgga tgctgtccaa gaaacgatcg cagtgcccga cgaacaaaat caacacgtat
     1861 ctctcgtgca gggcagtcgt tgaaaccgct acttgtacag attgccaatg ctcttctcag
     1921 atccaaagaa catccagaat ttaaaaatcg ctatcgtaga atcaaagcga atcgtggaca
     1981 caagaaagct atcattgcta tttgtaagat gctcctgacc gctatctgga atgtcttatc
     2041 aaaggtggaa ccctattctg ctaaaggata tctggagcca aaacctgcga aagaagagaa
     2101 agttctgacg caatcccaag ctctggacct tttaagaaaa cgcggatata ccattataga
     2161 tagtgcttaa accaaagtta cgttgattct tcctaaatag actcgttgtc ttccatttca
     2221 aaaattttga aaacggtagg cttatttagt gtaccgttct tcaggtatct tcaaatagat
     2281 ttattttcaa acttatttcc tttcttcttt tactctccta tagcttagca tttaagtggg
     2341 cactcgtgtc accttgctag atagctatga atgccgtaat aagcctccta gtatataggc
     2401 agactgccaa ttataactga ttcaatccac attatgataa aatccacctt ttcgtttcat
     2461 atgtgttgaa atatcacata tgtcaaaagt gcacgagtct tttcattcag tgctttgtaa
     2521 atactcaaaa ttattccttt tcactttaaa aaaaagataa ttagtacaaa atcagaaatg
     2581 aggaaagtat taggatggac tagaaaggag ttgttgaatt tgttgcaaca gattggtcat
     2641 ttatcaatta aaaattaggt gaagttttat tcatcactgc agctgctgtt tcccagagaa
     2701 taaaacgtct agaagaaact ggtcagttac tgtattatca agcagcaatt gactacgaac
     2761 aagcttgatt actaaccaaa gcgtttatcc acctgttgat taaatcaaat caaaaatcag
     2821 gtttttatac gttcataaaa gcaatctcca gtgtactcga atgtgactgt atcataggtc
     2881 cttattcgat gttaatcaaa atggggtttc cttctaccga atcattggac agttttatca
     2941 atgatttatc aaagtttgga cgaaccaaca cccaaatcgt tttctcgact cttgtttcct
     3001 taatggttta tcagttctgg aatgtttatc atgcgctttt attaaaatag aaaagagctt
     3061 ttttcatgcg acaaagcagt gatcatttat tggcacatgc aatctttgtg gatccatttt
     3121 ttgaaaatac gatatttagt tttgacccaa aaatctttaa atacgtattt gataatttat
     3181 cttaacaacc agataatttt attcagcacc gtattatcta tattgaattc tcggaatcaa
     3241 gataaatttt tttccgtttt tgtttctttt ttaatcttct tcttgttatt aatagtgatt
     3301 aggatgatat tcctatattg atctttgata attagatata atttttgaat aacgttccct
     3361 gctattcgag ctagaaatac aagtacgcca tgacctagtt agcgacaact acttagagat
     3421 ttcttttgtt ctgggacaac aaaatgccat gacaatagca gtaaataatg atacttccgt
     3481 aaggctcgcc gtaaactggg gagaggtgaa attcctatgt gcttacccaa agcggttcaa
     3541 aaattttaaa ctattatttt aggagatgat tttataaaat cgaaagccta cttgaataaa
     3601 aaacaagcct gtgaatttct aggaattgat aataatactt tagataagtg gattcgtgta
     3661 tataattttc cagtaataaa aattgatggc gtagttcgct ttgacgtaga ggatatcaaa
     3721 gatttcatga atacattcaa aaaaaattga aattttcttc tcgtcacata tactataaat
     3781 agcgaaatgt actgccttac tttttaaagg agtgaggaag tttgcctaca aagctttcaa
     3841 atgggaaata taaaactaat ctgaggtatc caaaaaaatt cagagaaatc actggaattg
     3901 catcagagaa gtatcaaaaa gtatttccaa ctaggcaatt agctattaag gccgaaaggg
     3961 aaatgaaaaa gaagattgaa acagttttaa gagaggagaa tgcaaactca ctagaattga
     4021 aaggaaaaat aaaatttaaa gatttttatg aatcaaaatg gcttcctaga tatgaactag
     4081 gtcaaactac taggtcaaac agggctccaa gtaatgtaac aattagtaat actaaggata
     4141 tattccgatt gcacatcctt ccaatgtttg gtgaatatgc aatgaattat ctgaattcaa
     4201 atactgagat aatatcagat gaattaacaa agaaatcgaa agaatacgca aatataaaaa
     4261 ttatcaaagg ctatgttcgc tctatgtttg atattgccga aatactatgt tatatcgaat
     4321 tcaaccgaac taccaaaatt attcaatgta ttaccgcgcc taagaaaatg gctttagaag
     4381 aaaaaaggat aagggaaggg aatcaagcat tatcatcaga agagctgact gattggatag
     4441 aagcagtaaa caatgactta aataatcact tgcttacact tcacgattac acacttttca
     4501 tgcttacctt atatctaggt gatagaaaaa gtgagactta tgctctgcaa tggaaatata
     4561 ttgattttaa taaaaatacg gttcgtctca aatatgcttt agataaatat caaagaaaga
     4621 cacatacaaa aggttggaaa gacaccgtta ttcaggcacc agaagttgtg atgacattat
     4681 taagagaatg gaaatcagct caggctgaac aattgttgaa actaaaaatt atacaaacac
     4741 ctgaccagta cctctttacc tattccaaac cttctggaga agtaaattgt cctgttcacg
     4801 ctgactactt aaactatcga atcaatgcaa taaaaaaaag gcatcctgaa ttggctcaat
     4861 tatctccaca caaacttcgt catacctatg caactatagc tagggaaggt ggagcaaata
     4921 tgaatcaaat ctctaatgct ttaacgcact cggatatttc tactacaaaa atatacgtga
     4981 acacacctga cgtagttgat aaatctgttt ttgaagcatt tcaaaaagga ttgaataagt
     5041 gtgattaaca tgtgttctca aatgtgttct tattataaaa aaagacactt tccaaataat
     5101 tgaaaagtgt cctgaaatat tgatataaaa agaatattaa cgttttgaga attgtgaagc
     5161 tttacgagct tttttaagac ctggtttttt acgttcgacc atacgtgcgt cacgagtaag
     5221 taagccagca cgtttaagag ctaaacggaa gtcaggatca acttctagca atgcacgagc
     5281 gataccatga cggatagctc ctgattgtcc agcgtatcct ccgccgttta cgttaacaaa
     5341 tacgtcatat gcgccttttg tttcagtaac agcgaaaggt tgattgatta cttcacgcaa
     5401 gtcagcatgt ggaatgtatt cttcaacatc ttttttattt acagtaattt tgccagttcc
     5461 tggtactaga cgtacgcgag caactgcgtt tttacgacgg cctgtgccga tatattgaac
     5521 ttgtgccaat gaaattccct cctattagat taagtttgtg atgtctaaaa cttctggttg
     5581 ttgtgctgca tgtggatgtt ctgctccacc gtatacgttc aattttgtaa attgtttgcg
     5641 gcctaaagtg tttttaggaa gcataccttt tacagaagtt tcgatcaaac gacgagaatt
     5701 tttagcacgc aattcgccag cagtgattga tttcaatcct cctgggtagt tgctgtgacg
     5761 gtaataaatt ttgtcagtcg cttttttacc tgctaatttc actttgtctg cattgatgac
     5821 gatgacgaaa tcgccagtat ccaaatgagg tgtgaaagtt ggtttatttt taccacgtag
     5881 tacagatgca acaactgttg aaagacgtcc caatggaaca tcagttgcgt ctactacata
     5941 ccatttacgt tctacttcgc ctggtttggc catatatgtt gtacgcacgt tattttcctc
     6001 caatttaagt tctgatgttt gacatacact tcgagtttcc ggggctcttt gtggggcaaa
     6061 caataccatt taacatatta cccgctaatc tagtcaatgt caacgttttt ctgcttgatt
     6121 gaaaaattta tatgaaactt tacttctttt ctttctttta tataaaaggg tcgtttcctg
     6181 tcaaaatgaa aaacaaaaag aggctgtgac aaaagtcttg tcacaacccc ttattttgaa
     6241 taaacggtgt tctcctgcca actcctcggt cacaagtcac aatatccata aaacataaga
     6301 agctgttttt taaaattgtt tcttgtgact cggagctgaa cggcaggctt acaacctctt
     6361 ggtaaacggt gttcaatcag ctgaccctcg gtattagctc aaaaaacggc aaaatatgag
     6421 gaactatttt gacgtttgtt tctctaatac tcaggtcaaa acgctgattt cacaacctct
     6481 ttttcggtca agttcaacaa cagtttttac gcgtcgatct ctggcgcttt gcccaaatga
     6541 gcttggatca tccagatacg tttttctgtg gctgttttga attcgataaa gatatcttgt
     6601 gttggatcgt cgccttcttc tccagaaact tcgattcctt tttggtaaag atctgctaga
     6661 taacgatagc ctgcaacaag tgtttccaaa cgttctggaa tagtacgatc ccagcggcca
     6721 atttcatcag ggatttttgt gttatctgca aattcacgca atgtagaata aggtgaaccg
     6781 tctaatgtga tcaagcgttc ggatacttca tctaactgag cgttcaaatc atccatgaac
     6841 tcatccatca ttgggtgcaa tgtaaggaaa cctggtcctc tcatgtacca atgtgtttgg
     6901 tgaacaacaa cagacatttg gcttagatct gcaactaatt gatttaatac ttctttggtt
     6961 tgttggaatt tcatctttct tgcctcctaa cattttctta cacttaaaat aatagtagac
     7021 tttcaatgaa aagtacaaca aaatcattta cctgagaacg attttcagtt cgctttttta
     7081 tccgtaaagc caatcatttt tcagaatcag ctaattcttc tcgcagttga gcaaattgct
     7141 gataagtctg tgctaaatgc ttttgtgtcg aaacaaataa tggatagatt ttctgatatt
     7201 ttttatgatc agtttcttgt actccaactt gctctttcaa ttctatcaat tcctgtgctt
     7261 cactgatact ttggatcttt ccgatgcttc tccagcctaa aatcacagct cctaatgcgg
     7321 atgcttctgt gacagtaggg aaaacaagcg ggtaacccag tacatcagcc atcatctgac
     7381 gaaaaatcgg agattgagca aacccgcctg tagcacggat ctctgtgagc tgattttcct
     7441 ggcaaactcc ttttaaaatc cgataaaggt tgagacagat cccttctaga atcgccttca
     7501 tcatttcttt ttctgtatgt tgccgctgta aaccgataaa actgccaaac gcatctgcgt
     7561 cccaaagcgg tgctcgctca ccaagtaaat agggatgaaa aatcagacca ttggcacccg
     7621 ctggcacaaa agcgatagcc gaaagcagtg catcatatgg attttctcct ttttctttag
     7681 cagattgaac gacttcctgt aaaaatgtat gccctgccca atcaaagatg ccagcaccat
     7741 tgctagtcgc tcctcccact acccaatgtt tctgatccag aacataacaa aacgtctcca
     7801 tttctggatg gaactgaggc tgagtagtaa taaaacgaag tgctccgctc gttcctacgg
     7861 tcaaagcggc gatcgtatca ccaaaagcac ctaaccctag attagaaagc ggcccgtctg
     7921 cccctcccaa aacaaatgat atatcatttg gcaaacctag ttctgctgct gtttttgatg
     7981 gtagacctgt tacttgatag gtggaaggaa agacttgcgg caattgctct attcgaatgt
     8041 tcaagtagtc aagcacttct tctgcccatt ggaattcatg gatatcaaaa tatccagttc
     8101 ctgaagctgt tccgtagtcg ctgatcagtt cgccaaacaa tctataaaag atatagtctt
     8161 tgataccgac aaaataagca gtttttttga ataattcagg ttggctgttt tgcagccact
     8221 tgattttgtt caatggtgtc attggatgaa tcggcgtccc agtctgccga taaaattctt
     8281 tgccaagcac ggtatatttc agtttttctg cttcgtccgc tgctcggtta tctgcccaag
     8341 tgatcattcg agataacggt gttttctctt catccaacaa tatcaggcca tgcatcgcag
     8401 aggagaagga gacaaattga atgattgtgt ctgaaggcaa ctgtttaatt acttctttta
     8461 taacggtgca gacaccttga aagatcaatt cctgatcttg ttctgccatc ccttgtgttt
     8521 cttggatcaa agggtagcga aaataagcgg atgctgcttc ttgggcttca tctgtgaaag
     8581 caactgcttt ggtttgtgtg gttccgatat ctaatccgat tgaaacgttc attttttcac
     8641 ctcaaatttt atgtatgtac aaaaatttag tttaagcttg cgtatcttgg ttttgaaaag
     8701 ggggagatgg cgtgttactt tattttatca ttggttgctg tatcggatca tttttatgtt
     8761 taaccgccca gcggattccg ttaggtcact ctattattta tcctagatct cattgtgtca
     8821 aatgctgtcg ttcgctttct tggtatgaat tgattccgat tctctcgatc atcgtccaac
     8881 gatttcgctg ccgctattgc aggtgtcggt tgcccttcta ctatttgttg gcagaagcct
     8941 tatgtggtgg tctttttgcc tggttcttta ctttttcttc cgcaagaaat ttttcgacgt
     9001 tcatatggat gctttcggct ttgctatttt cgttgatgga tttattttac ttcatggtcc
     9061 attctcacac gctattctgt tcttgggcaa ttttatggat tttttggttg caggccggcg
     9121 tcttccaatg gcaaagtgtg ctgttaacgt ttatcgtagg cggtgtgtgc cttcgctatg
     9181 gtcaatccta tctcggagct ggcgatactc tgttgatgct ttcttggagt ggtggcttgt
     9241 ctctagaaga gttgcttcag atcttgtttc ttgctagtct gtttggaata tccgtttttt
     9301 ctgtttactt tatctgtcat aaaaaaaagt tggaaaagct gcctttcatt ccttttttga
     9361 gcagtgcgtt gctgattgtc cttcatctta ggtattgaaa aaaggttgtg acaaacgact
     9421 tgtcacaacc tctgatatat agtgttctct taccaaatcc ttgtgacttg gagctaggcg
     9481 acaggttcac aacctctcca ctaaatggtg ttcaatcagc tgaccctcag tattagctca
     9541 aaatgctggt tttacaacct ctgatatacg gtgttccata agtagctttt tcggcttctt
     9601 atttcttgac gccccaatgt cgacgaagga aacctgcacg tccagaacct tctcgataaa
     9661 gattgtaatg gagcttgttt ttcttgtaat aatcctgatg gtaatcttct gcaggataaa
     9721 attcgcttct tggttcgatt tttgtcacga ttggcttatc gaatcgcccg ctgtcttgca
     9781 atgcttgttt tgaacgctct gcaatatttc gttcttcttc atcattatag tagatcactg
     9841 gacgataaga atcaccgcga tcagcgaact gtcctaatgc gtcagtcgga tcggtttgct
     9901 gccaatagat ttccaccaac tgatcataag aaataacttc tggatcatat tcgatctcta
     9961 ctgcttctgt atgccctgtt gtgcctgttg ttacttgttc ataagttgga tttggtacat
    10021 gcccgccagt ataaccggat gtcacagaaa tgatccctgg ctgctcttca aatggtttga
    10081 ccatacacca aaagcatccg cctgcgaaaa ctgctttttt tgtcatataa aatccccctt
    10141 ttttctcatc ataccttgat ttccaaaagg aggataacgt tttgcttgtg acagaaaaaa
    10201 cggaaactat tatatacgtg atacggcttc tgataaatgc caaaacgaac gtacttgatc
    10261 aaaaacggtt aaatcaggaa tcacatattc agcagaagga agatttatgt tttcacctat
    10321 tcccaataca tgcatgttac cagccaaagc tgcttgacaa ccagcttctg aatcttcaat
    10381 gaccaagcat gcatttggcg gtacattcaa ttgctgtgct cctttgagaa aaacttctgg
    10441 atcaggtttt gcttttgata cttgcgtgcc gtcaataagg acatcaaaat aacttgtcaa
    10501 attcgttttt tctaaaatga ggcgtgcatt tttgcttgct gatcccaatc cgatcttgat
    10561 gtttgttttt ttcaagtact caagaacagc tattgcacca ggcaaaacgg atgtttcatc
    10621 cattttttga atcgcttgaa gatatagatt gtttttttgc tcagcaaagg ctgatttctc
    10681 tttttctgag aatttctgtt ccatttttcc aaatgacagc aatcgctcta gtgactcggt
    10741 tctggatatt cctttcagtt gctcgttttc tttctcagtg aatggaatgg acagctggtt
    10801 agctaaaacc agccacgctt cgtaatgata acgagctgtg tctacaagaa cgccatctaa
    10861 atcgaatagt gctgctttga ttttcatcga ttacctcctt gaaaatgaac gacttgaagt
    10921 aaagatgcga tgtttttagc tgtgcgatga agattatcag tggcttgctg taaagcttct
    10981 tgtaaaggca cagctgcagg aaggatcgga aaaacggccg aaatgccaac atctgctgct
    11041 ttttcgcttc ctttaccaac acttccgcaa atagctatca caggaacgcc ctctggtact
    11101 cttctagcaa tcccaactgg cgcttttcct tttagacttt gtccatctag acgtccttcg
    11161 cctacgatta cgaggtctgc ttgctgtacc cgtatcgaac tccagtaaat ccaatacgta
    11221 gtcgatgcca gagactattt tccctgaagc aaatgctaac agtcctgcac ccattccacc
    11281 accagcacta ctgcccgatg cctcgattac ttgaggggca aatctcatat aaaaatcatg
    11341 catggcttgg tcagccactg ctaattcatt ttctttcaag cctttttgtg gtccgaaaac
    11401 aaaagaagcg ccttcttttc cgcataaaag attagtaaca tcagtaatga cagtgatttt
    11461 ggctttaatc agctcaatag gcacgttcgt tttatcaact gtagcaattt tacctagatt
    11521 ttctcccagt gcttctactt tttgattatc ttgatcgtaa aaagcataac ctagaccttc
    11581 tgccatgccg atgccgccat cgttggtact acttccgcca acgccgatga tgatgtgtcg
    11641 aacaccttgt tgcaacaatt gtcgtatcag ttctcctact cctcgcgtgg ataacctaag
    11701 tggctgttgt tggtttagtg ggacatcttt caatccgacg atttctgcca tttcaaaaat
    11761 cgcagtttga ccgtctgaag cgtactggat ttctttgttt ttgccaaatg cattagtaac
    11821 gactgctgtt tgccgcttca accttaaact gtctgctaat gatgaaaccg ttccttctcc
    11881 tccatcgcct ataggtagca gatcatattc agcctgaaca aaaacttctt gaaaacctga
    11941 ttgaatggct tgtgctgcct ctaaggctgt cagactttct ttgaaagaat ctggcgcaat
    12001 cagaatacgc attattttcc cctccgttcc aagatcagtt ctttttccag ctggtattgg
    12061 tctccattga caaaaatagg taatgtttct ttcgtctctt tttttattac tatttgtttt
    12121 tttgtcaaaa caaatagcaa cctgtgattt ttccaaataa aaggaaaaga aattttttcc
    12181 catgctgaag gaagtcttgg agaaatagaa agagttccat tcgttactgt aatacctgaa
    12241 aaaccaaata taactgctag ccatagtgct cctaatgaag cagcatgaat tccgtcatct
    12301 gatgaatgcg gatctggtcc taaatcaatc aggcacgctt cttggaataa atgatacgcc
    12361 cattccattt cttggatacg gcaagcctct atggcgtgaa tcgctttact caacgatgag
    12421 tcgtggattg ttttgttttc atagtaatgc aaattcttag aaacgattgg ttgagaaaaa
    12481 tactcaggta ataagtataa cagcatgaca agatctgctt gcttgctgac ttggagttca
    12541 tttacttcgc tacgggcata atcaagtaaa atagactggc tgccaggacg ttctttgtaa
    12601 gtggtcaaat caataactgg cttactgaga tacgtgtcat cttgcggaat cagctgttct
    12661 ttgttaggca ctggcaaata taacttatct aaaaaatttt gacattcttt caaaaaaagc
    12721 ggatcgccag cttgatattt aacagctaag gccacattat aatgcgccag atagttcgta
    12781 tatgcattat tgtcgatata ttctgtgtat tcatctggac caatgactct gtgtatctct
    12841 aaatgatcat cgacttttac agctctgctc agccaaaaag ctgctgtttc atgaatgagc
    12901 gtttttccct ttgtttctaa aaacgattga tcctctgttg cttggacata ctcttgaacg
    12961 gcataagcaa ggtctgcact gatatgatgt tctgcggcag ctgaagcaac ttcttgtctt
    13021 gttccggttt tgatattcaa tgcagcaaat ttgggtgtct cttcctgacc agtgtgtgcg
    13081 ctttcccatg ggaaaagtgc accttgatag tgataatctc ttgctttttg ccgtgcgcct
    13141 tctaatcgat cataacggta cagcagcaaa ttctttgcta cttcaggaaa ctgatataaa
    13201 aagaaaggca ggataaaaat ttccgtatcc cagaaaacat gccctttata accttcgcca
    13261 gttagtccct tcgcccctac actaacactt ggatcattgc ggggagtcat aatctgtaaa
    13321 tggtaagcag cgaagtccat cgctaactga tcgaaagaag aatcgccttg gatcgttatc
    13381 cgatgctgat gccaaaaatc tgtccaataa gacatcgact gctctaaaat ttctgtataa
    13441 ctaacgcttt tctgggcttg ggcaatactt ttcttaaacg ggtctgtttg ctgaagagag
    13501 gtagagagca cgatgatctt ctccagcgta aaggacgtat tttttctgat cttttctgaa
    13561 aaggaagcgg tgatccggcg attttttgct tggaatacac ctgctttatt gaatttagct
    13621 gcaatcccaa tatcaatttt actttctgtt gtctggtagg atgcactgat caaatcgtca
    13681 ccaaatactc gcagttcttt ttcaaccaac tgctgtgtac caaaattggt ttgctgtcca
    13741 tcgatacccg ttttcacatc tacttggcag tcttcggtca acggcttgat gaccactttc
    13801 agggctgcct gatggagatt attttgatca gcaacacgac aagtaatgac ttccactttt
    13861 tttccttgag cagtttcaat gagcgcatag cgtttaagct ctcccatttc taaatctagt
    13921 gcccgctcgt atgcaagaac tttcatcgtc tcaagagaaa aatgttcacc gtcgattttt
    13981 atttcccatc tgatgacatc tgggagattc actaactcgg ctgattctgc tcctaaaggt
    14041 cggttatata caccagctgc aaacattccc cttacttgat tccgatagtc ttcctcctgg
    14101 cttcctctga taccaaaaaa tccatttcca atggtcatct gactcgcata cttattgata
    14161 tactctaaat caaactgttt ttcttctact ttcataaggt aataacttct cctgtttctg
    14221 ccgaacgata taaattttcc accagattct ggatgacata tccttgccag ccatctgcaa
    14281 tcatctgagt ctggtcaccg agcgcccgat tcacaaaatg agccatactt agttcatgtg
    14341 ggtcattaac tggcgtggtc ttttgtaagg aaaccagctt tccatctaca tcttcgaata
    14401 gttcgcctgg atacagatta gcacctgcct gatcgccaca aaaagccaca ttcagtttgt
    14461 cttctctgat attcaaagca aacgaagtat tcagttggat gatcttgccg ttttctaatt
    14521 ccagtgtgcc aaaaattgca tcttctactg tgaatttgct tggatcccat ttcccgaatt
    14581 tccctgaatt ttttttcgta ccaatttttt ggaagctgta cgcccgaacg ctttttactt
    14641 taggaaatcc agtaatatac atcgctgtat caagcatgtg aatgccataa tcgatcaaag
    14701 gcccgcctcc ttgaagttct ttgtcgataa acgttcccca gcctggaaca ccagaccgac
    14761 gaagcgcatt cgcttctacg taataaatat ccccgagaac atcaagatga ttcttgatca
    14821 ttgttgcttc gtcagaaaaa cgatgctgga atccataagc caaaatctgc ccgtttttat
    14881 cggctgtctc tgccatcttt cttgcttgat cagctgtcat agctggtggt ttctcgcaca
    14941 tcactgaagc attagcttcg agggcagcca atacatgttc gaagtgaaag cgattggctg
    15001 tacagacact cacgatatcg ggagaaatct cattcagcat ttgtgtaact gatgtatacg
    15061 catgagaaaa tcctgtacgt cggcaaaagt cttctgctcg ctggctgact ggatcaacca
    15121 cagcggccaa ttctaagaca tctgatcttt tttgataata agcagcatgt actttttctg
    15181 ctacttgtcc agcgcctatg attgctactt tcttcattta tttctctctc ctttgcttat
    15241 ttacttattg ttattctttc tctattcttt ctctaaatca tttaaatgac gcgctgtttc
    15301 cagacagttt ttcaagtatt gcaatgattc ctgataaatt ttcacttcat tttctcctcg
    15361 caaacgacat tcatatacca tataaccttc atactcattt tgaagtagcg tttgaaaatg
    15421 gcgagtaaaa tcaattgcgc cagatcctgg ttggtagcga tgattatctg ctaaatggat
    15481 atgacccaca tactcttttt gcgtagtcaa tgcttttgaa atatcatctt cttcaatatt
    15541 catatgataa aaatcagcga tgatctgcac atgtttcaat tgattagagt caatgtaatg
    15601 acgcgcatcc gctaacaaat tgatcatatg gtcttggtat cggttcaaag gctccaaata
    15661 aataaccgta cctgtttctt cggctacttt atctaaataa cgaagtgatt cgctgactgc
    15721 tttatagtct ccttctttgc ttcggggtga aaccatcggc ggtaatcgat aagtgaacat
    15781 tccccaagct gctgggataa cgattccttt gcctccaacc tcgcttagtg cacgcaaaat
    15841 ctcagcaatt tgacgtacac cattaagacg ccgttcttcg ataaagtcac cgatccaccc
    15901 atcgtagccg ttacaagctg tcactactgg gatccctgtt tctttgattg cctgtttgac
    15961 tgtgtcgata ttttctatta acaacttacc gtcgatttcg tattcttcaa atccacagtc
    16021 tttgataaat ctaaattttt ctaaaatgtc tcttgggaaa aatgcttgat cttgcgtacc
    16081 gaatttcatt gttctcctcc tcggacttga acgcccattt tgatactttc ttctgggtgc
    16141 tggtctacat aacgcatgta agcttctgcg ctttctgcaa atggcacaac tggatcaatg
    16201 atttcttcac aatccaagta accgttcatc aataattccc aacatgtgtc ctcgattcgt
    16261 ttacggttcc atcttgggta atctgggttt ggttcactag atgctcgagc aaagacgatt
    16321 tttgcattat tgaaatgtgc ttcgcgacca agattaaacc cagctggaaa aggtttagca
    16381 aaggcaacat aagaaatgat cccgccatag ccgatccctc ttaaagaagc ttgtaatgcg
    16441 gcagcactgc cactcgtttc aataactgaa tctactccac gtttatctgt caattccttt
    16501 agacgaaaac cgacatctgc tttcatagga tctagcgtgt aatcggcacc gtatttttct
    16561 gctaattctc tacgctgcgc tatgggatcg atcccaacga tggtagtagc acctgctttt
    16621 ttagctaatt gaatcgcaat ttgcccgata gcgcctaaac cgaagattgc tacagcatca
    16681 cctgctcgaa catgtgcttc ccggatacca cctaaagcga attgagcagg atcgtaacat
    16741 actgcatttt tccattgatc caaccgatca agtttacgta gtttataatt atcaacaccg
    16801 tttgtaatca gcgtttcacg aatgggtcca taagtgcaga ctaactctcc tttttgatac
    16861 tctgtcacca aactgcccgt ttcttcgatc gtaccgacaa tcatatttcc taattgaaat
    16921 tcgccaaata ccacaccgcg ttggcttcct tcttctcttg gcaagaatag gcgccattct
    16981 tctgaaaatt cttcatcgat aaatggactt aatcctctaa agtcgacaat ttctgttcct
    17041 ggttttggag tagcgaaaat tactcggata cgtacttcgt tcttttcgat ctcacggtct
    17101 tcgtaatctt tgaatccggc tattcttggt tctaatgcaa ctaatttttt catcttttct
    17161 ttcctctttc ttttcttttt atccttttac gccgccttcg actaaatcac ctttaataaa
    17221 tcgttcagat aacgcataca taatgatgac tggtaaagcg gtcaccaatg aagcggccat
    17281 cattcgtccc caaatgtagt ctggtgtact gaataatgtg ttcaaaccga ttggtaaagt
    17341 aaatttttcg gaggtcgaca ggaaaatcga agcaaataaa taatcattcc acgaaaccat
    17401 aaagcaataa acgaagacag aaatgattcc agaaatagcc aatggtataa tgatccgaat
    17461 aatgatctgg atccggctaa gaccatcgat cattgctgct tcttcaatat cagtcggaat
    17521 cgtgtcaaaa taacttttta gcatgaatat cgcagtagga agtgtttgaa cgaccatcgt
    17581 gataatcagt gctgtattgg tatcatacaa acctagaccg gaaatgattt taaataatgg
    17641 aacaacgatc aaaataccgg aaaacatata aacggtgtaa aagctagcat tgattttcga
    17701 gcgagctttg aagcgtagtt ttgacaaagc gtatgccccg ctgatcccaa tcactactgc
    17761 agttacggag gctatcaagg agatcactaa actatttttg aaatacatga tgaatggaaa
    17821 aatctcagca ttgaaaatat cctgataatg ttcaaaagtc cattctttcg gaaaaatagt
    17881 ttgtgtcgtt gcaattgctt cttgtgaatc cttgaatgat gtcatcagca tgatcaaaaa
    17941 tggaaacaaa ttgacagcta atagcaacaa aatcgtcgcg taaaataaga ttttcctgct
    18001 ctttttattt ttcatttcaa gtccaccttc tttcgtgaga gcaagacgac cgctgcaata
    18061 atgatgaaca atagaatcga tatagctgct gcttttccaa gatcattgaa cgcaaaggct
    18121 gtctgataca aataaacgcc taagatattg actttattcg tcagtagata gacatctgta
    18181 aacatataga acatccagat agatcgtaaa acaatcacag ttgctagtac tggtttgatt
    18241 gccggcagtg tcacgatctt gaacttctgc caagcatttg caccgtccat ttcagctgct
    18301 tcataaagcg ttttgtcgac tgtttgcaaa atagccaaaa atgaaataaa cgcatacgga
    18361 tagtatctcc agatagcaaa caaaacgacc ataaagaagc tagcaactgg ctggtcgaac
    18421 cacagcggtg cttcgttgaa aagctgcaac ctatctacta acagatcatt gacgattcca
    18481 taactattat tgaacatata tttccaagca aaaatcaaag aaatagatgg cgtaacataa
    18541 cttaataaaa tcagtgaacg caccgttttc ctaaatctga acttgcggtt aagcaaaata
    18601 gctacggcta atcctaaagc tgtactgcct gctacaacta agaatgtgta agcaactgtt
    18661 aaacctaaag aacgataaaa ttcactatca cttaaaattt caagataatt gcttaatccg
    18721 ataaaaacgg cgtctgagtt aggattcagc ggcatatcga aaaaactgat ctgaatattg
    18781 gaaagcattg gaatcagcac taaaacagct aataaaagca tgcttggtgc taaaagtccc
    18841 atggctaatt ttaagtcaga atgtttcctt ggacgattca ttgaaacctc cccctgataa
    18901 tctgccaata gctatctact tttttcgaac accattggca gaacttcttg ttatttcgta
    18961 tttttttgtg cgtcagctaa agcttgatcg acatcttcgt ttccgacagt tacttggttc
    19021 actgcttttc cgatcacacc tgagcttgtg atatctccca ttttcgtgaa attcttttcc
    19081 ccgactagtc caaagacttg tacttcatca aaagcactag caatctcaga tggcagctcg
    19141 ccaaaagact tgatgacttc attttctttg taaccatcca gttcgactac ttgtttattc
    19201 actggttgag caccaccagg agacatcaag acccactttt ccatgttttt cggttgagat
    19261 aagaaagctg tgaatgcttc agcagcctct ttttgtttct cgtctagacc agaagaaatc
    19321 gtcaatccag atactgtgcc atagacagct tgatcttttt gtgttgggat agcaaaaccg
    19381 atattttctg agttccccgc ttcataaaca gaaggcaaaa tgtaagttga atagattgcc
    19441 attggtgctg ttccattcat gaaagcatct ttgatttctg tcacatcatt agagcctggc
    19501 atcgtgtatt gggataagtt ttgataaaac gacaatgctt ctctcatctt ttccgtatcg
    19561 atcgttacct cgccttcatc atccaaaaca tttgctccat ttgacaaagc aaattgagag
    19621 aacgcttgct cactcattgt tccttcagca gtaggcatag caattccata ttgtttattc
    19681 tctttatctg tgaaatgttg agcaattttt aaaatatcat cccaattttc tggttctgaa
    19741 aaaccagctt ctgataattt ttctttgtca taccaaatac cttgaaccca gccgctaatt
    19801 ggtgcagcaa tatagctttt tccatcttct gaacgaacaa ggtttttggc tccgtcataa
    19861 taattatctt ctccagcttc ctcgataacg ttttggactg ccgtctgatc aatcagttca
    19921 tctttatcca tcactttagc aaaatcctga ctgacttcca ttacttctgg taatttaccg
    19981 gaacgagcta acgtaacgat ttttgtattg aacgctgatt cttctaccgg cacttgcttg
    20041 attttgatgt ctggattttc tttttcaaaa tcagcaacca gttcattgat cacacttaat
    20101 cgttcctgtt cgacagaaga gtgcatgaat tgaatcgttg tctgttgtga ttcgttagag
    20161 ctttgacttt caccacaagc agtaagaaga aatccagtag ctagcagaca ggtagtaaca
    20221 ataatttttt tcattttttt ccacctctta ttttattatt ttcagccaca tatattcata
    20281 cggctggaat atcaactttc gttcttgact gcaatggata atttgtccag aaaacaggtc
    20341 taggtaatct ccttttggta aaagataacc tgctgattga ttggaaaaat tatggataac
    20401 taagactttc tcttccttcg cttcgcgaat aaaactgata aaagaatctg ctgagtccag
    20461 taagtaaatc aaactattcg gatggaaggc tttttctttt tttcgaatag atagcatctg
    20521 ggtcaattca ccatatactg ctgttcttaa tggatctgtc tgcaactctt tctcaatatc
    20581 tgctaacaaa aatttttgcc gattgatttt tcgattctct cctgtttttt ctacgccttt
    20641 gtaatcattt cgacttccca gcacactttg aatataaatt gccggcacgc ctggtaacgt
    20701 taccaaaaat gaatgagcag ctaaaaagcg tttgcttctc cattccgtcg tatctgttgg
    20761 agaacttaac gcatctagat acgtagcgtt tatctcatat ggactggtcg ttccatctgg
    20821 gtttttcttg tagtttactc gggcaccctc tttcttcagc tgttccacta attcaaggat
    20881 cgttttttcc ggcagaatac ctcgtaccgg attcaatccg ataccgtcat gggaggctaa
    20941 aaaattaaaa aaagttgttt ttttcgatgc gaaatcgatg gtttttaacc attctttcaa
    21001 cttacttgta ttacccgaac gaatcgcttg aagggtcaaa ggtggtagcg aaaactgata
    21061 gaccatctgt gcttcattct cgccattccc aaaataactg atattatctt tgtgtggcac
    21121 atttgtctca gtgatcaata ccgttcctgg agctgcttca tcagcgattg cacggaataa
    21181 ttggatgatt ttatgcgttt ctggcaggtg tatacaagaa gttcctagtt ctttccataa
    21241 aaatcccaca gcgtccaagc gaataaatga agcgcctttt tctaagtaaa acaaaagaat
    21301 atcgatcatt ttcaataaaa cttctggatt tttaaaattc aagtctactt gatcttcgct
    21361 aaaagtcgtc catacgtgtt tttctttccc gtttttgtca atgaacgttg taagtaacgg
    21421 gctggtcctt ggtctagtca cgctgcttgt atctgtatcc agtggcaaat caataaaaaa
    21481 atctttgtac gtatcattca agtttaaata ttcctgaaac caagtacttt cggcagacat
    21541 atgattgcag acaaagtcga acattaaccg tgtttcgctt ctcatttctt ctatatcttc
    21601 ccatgtgccc aaacggtcgt tgattgcctg ataatttaca acggagaaac catcatcaga
    21661 tgtatatggg aaaaatggca agaaatgtac aactctaaat gtatctgcca aatacttttg
    21721 ataaaatttc ttaaatgtac gcaaagttgg ttgctgctct tcaaaaaatt gatccccata
    21781 agtaatcaag aaaatatctt cttcgtccca atgcagtttg cctgcctggc ctttcttctg
    21841 ctgataaaca ctgacttttt gttcaatcat agaggcggtt ttctcagaca aatctgagtc
    21901 gcgataaatc gcttgtaaaa gttttgtata catcggattc ccctttcttt tttgggagcg
    21961 ttcccaacga tttgatcata ttatggaaaa cgcttactgt caatagcatt tttttaaata
    22021 attttgatat acacaaaaat acaaataaga aagcttatgt atcaataatt aatagcttct
    22081 taaaaaaata tggtctctca tgatcatgca agctattcct aaattttcaa aatcatagac
    22141 aaaaaagaat gtctattgta ctatggaatt attctaaaac gctcccaaaa aggaggtgca
    22201 tataaaattg aaacctacta tttatgacat tgcgaaaaaa gctaatgtct caaaatcaac
    22261 tgtctccaga gtattaaata accagccaaa tatctctgat aaagcaaaag caagtgtact
    22321 tcaagcaatc aaagaattga attatgaacc gagcaaaatt gcaagaggac tgtcaggaaa
    22381 tggttttgac gcgattctag cattatctca tcgtacttct catacgacct atggcaatcc
    22441 ttttttttca gatgttattc aatccatttc tgccgtttct gaacaaaata acttcgactt
    22501 gattctacaa acggcaaaaa caccagaaga agagctagaa aaatgcgcga aaaagatcca
    22561 agaaaaaatg atccgaggaa ttattatttt aagctctacg atggatgaaa cacttctttt
    22621 tgaattggat caatacaata ttcctattgt ggtaatcgga aaagtcggaa acgactacac
    22681 gaacatctac tcagtggaca cggataattt ccaggatagt tacgatttgg tggaaacact
    22741 gatcaagaat ggacaccgtc atatcggctg tctccatgct ccgacagaag tttatgtatc
    22801 caatgatcgt ctcaatggtt accgtcaatg cttatttgat caccacctag atatccgtaa
    22861 tgaatggatt atagacggcg gctttcgctt agaagatagc atggcagcaa tgaatgattt
    22921 aatgaagcta cgagaaagac caactgcgat tttttctacc gatgcattaa aatcattgag
    22981 tatttacaaa gtggcagaac aatctggaaa gcagatacct gatgatcttt cgatcgcagg
    23041 attcagtgat cccttattgt cctccctatt ttcgccacag ttgactcgga tagacattcc
    23101 gacaaatcag ttaggaatca aagccacaga acttttattc caactaatcc accaccaata
    23161 ccctgaagaa aaaagaatca ttctttcaac cgagattact ctcacagatt cgatccaaca
    23221 acaagaaatg tagaacagaa ttataaaaga acagaaacac tgaggataag tcagttactc
    23281 tgttcttttt tcaatcactc atccctcgtt accccctccc ggtattttag cgaatttttc
    23341 ttattttcca tctgttttag atagctgtgg ataactataa tgtttgtgtt aaactatttt
    23401 ttccacaggg aagaaaaaac tatttttaac cacgttgtgt ataagttttt atagttcgtt
    23461 tttttaaaca catttaccct tatttcaatc catgttattt ggggatactt atctctaaaa
    23521 cataaataga ataacagaca tgtctactgg ttttgtttta ttcgaggaat tattcaataa
    23581 tagctagcaa aatattaaaa ataaccgctc tatcttccca tcaatttatt ttgcattcaa
    23641 aaaatgatct atctttactt ttgttgattg acttctcttg gaagatgatc gttccgatac
    23701 cttaattgga tacgaaccga tgttgttaag atcctttccc acttttcttc tagttagaca
    23761 aattatttta ga
//
LOCUS       DAZUJR010000044        23654 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.044, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000044 DAZUJR010000000
VERSION     DAZUJR010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23654
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.044"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(27..602)
                     /locus_tag="ACG804_001625"
     CDS             complement(27..602)
                     /locus_tag="ACG804_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytS/YhcK type 5TM receptor domain-containing
                     protein"
                     /protein_id="HFS4832560.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(607..1581)
                     /locus_tag="ACG804_001626"
     CDS             complement(607..1581)
                     /locus_tag="ACG804_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HFS4832561.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIASALKVNPNIGKHMERFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEEAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(1605..1649)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1864..2832
                     /locus_tag="ACG804_001627"
     CDS             1864..2832
                     /locus_tag="ACG804_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFS4832562.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMN"
     gene            2929..3222
                     /locus_tag="ACG804_001628"
     CDS             2929..3222
                     /locus_tag="ACG804_001628"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4832563.1"
                     /translation="MRSAAYGNQRRKNRLALFNDEQQEIGEMTWSDAGPDIMIVDHTF
                     VDPAYRGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            3340..3576
                     /gene="secG"
                     /locus_tag="ACG804_001629"
     CDS             3340..3576
                     /gene="secG"
                     /locus_tag="ACG804_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HFS4832564.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            3679..4434
                     /locus_tag="ACG804_001630"
     CDS             3679..4434
                     /locus_tag="ACG804_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFS4832565.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            4437..6794
                     /gene="rnr"
                     /locus_tag="ACG804_001631"
     CDS             4437..6794
                     /gene="rnr"
                     /locus_tag="ACG804_001631"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HFS4832566.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKTRNGKSGKRE
                     GKQAGKRPERNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            6816..7280
                     /gene="smpB"
                     /locus_tag="ACG804_001632"
     CDS             6816..7280
                     /gene="smpB"
                     /locus_tag="ACG804_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HFS4832567.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIIRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            7582..8301
                     /gene="atpB"
                     /locus_tag="ACG804_001633"
     CDS             7582..8301
                     /gene="atpB"
                     /locus_tag="ACG804_001633"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HFS4832568.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            8354..8569
                     /gene="atpE"
                     /locus_tag="ACG804_001634"
     CDS             8354..8569
                     /gene="atpE"
                     /locus_tag="ACG804_001634"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HFS4832569.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            8660..9184
                     /gene="atpF"
                     /locus_tag="ACG804_001635"
     CDS             8660..9184
                     /gene="atpF"
                     /locus_tag="ACG804_001635"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HFS4832570.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            9171..9713
                     /locus_tag="ACG804_001636"
     CDS             9171..9713
                     /locus_tag="ACG804_001636"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HFS4832571.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            9736..11292
                     /gene="atpA"
                     /locus_tag="ACG804_001637"
     CDS             9736..11292
                     /gene="atpA"
                     /locus_tag="ACG804_001637"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HFS4832572.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGSNSST
                     EDKLKSIQNA"
     gene            11306..12208
                     /locus_tag="ACG804_001638"
     CDS             11306..12208
                     /locus_tag="ACG804_001638"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HFS4832573.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMFQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            12231..13637
                     /gene="atpD"
                     /locus_tag="ACG804_001639"
     CDS             12231..13637
                     /gene="atpD"
                     /locus_tag="ACG804_001639"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HFS4832574.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            13651..14073
                     /locus_tag="ACG804_001640"
     CDS             13651..14073
                     /locus_tag="ACG804_001640"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HFS4832575.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
     gene            14542..14772
                     /locus_tag="ACG804_001641"
     CDS             14542..14772
                     /locus_tag="ACG804_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HFS4832576.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            14869..16170
                     /gene="murA"
                     /locus_tag="ACG804_001642"
     CDS             14869..16170
                     /gene="murA"
                     /locus_tag="ACG804_001642"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFS4832577.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            16183..16359
                     /locus_tag="ACG804_001643"
     CDS             16183..16359
                     /locus_tag="ACG804_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFS4832578.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            16494..16790
                     /gene="yidD"
                     /locus_tag="ACG804_001644"
     CDS             16494..16790
                     /gene="yidD"
                     /locus_tag="ACG804_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HFS4832579.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            16854..17321
                     /locus_tag="ACG804_001645"
     CDS             16854..17321
                     /locus_tag="ACG804_001645"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4832580.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASNQTRIIIRTGTTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            17406..18290
                     /locus_tag="ACG804_001646"
     CDS             17406..18290
                     /locus_tag="ACG804_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFS4832581.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKTQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLD
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLIGAAANYLAVRQGEN"
     gene            18404..18640
                     /locus_tag="ACG804_001647"
     CDS             18404..18640
                     /locus_tag="ACG804_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HFS4832582.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            18728..18808
                     /locus_tag="ACG804_001648"
     tRNA            18728..18808
                     /locus_tag="ACG804_001648"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18762..18764,aa:Tyr,seq:gta)
     gene            18815..18886
                     /locus_tag="ACG804_001649"
     tRNA            18815..18886
                     /locus_tag="ACG804_001649"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18847..18849,aa:Gln,seq:ttg)
     gene            19012..19182
                     /locus_tag="ACG804_001650"
     CDS             19012..19182
                     /locus_tag="ACG804_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832583.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
     gene            19402..20109
                     /locus_tag="ACG804_001651"
     CDS             19402..20109
                     /locus_tag="ACG804_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFS4832584.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRRDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(20168..20812)
                     /locus_tag="ACG804_001652"
     CDS             complement(20168..20812)
                     /locus_tag="ACG804_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HFS4832585.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKNFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSANHFKESIIELLNGQVQFEEGSVSYHEQLITDHI"
     gene            20939..21226
                     /locus_tag="ACG804_001653"
     CDS             20939..21226
                     /locus_tag="ACG804_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832586.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            21334..21654
                     /locus_tag="ACG804_001654"
     CDS             21334..21654
                     /locus_tag="ACG804_001654"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFS4832587.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIA
                     LIGE"
     gene            21735..23048
                     /locus_tag="ACG804_001655"
                     /pseudo
     CDS             21735..23048
                     /locus_tag="ACG804_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
     gene            23045..23464
                     /locus_tag="ACG804_001656"
     CDS             23045..23464
                     /locus_tag="ACG804_001656"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832588.1"
                     /translation="MRCSCCGKDIIQNLTFSEIIGVSKSRLPQTCSVCRAQFHLLEAK
                     GCAGCQKPIHLKYEETKKKANTSFVYCNDCQEWKKKYPAYDFQHRAFFTYDEKMQAWI
                     NRYKFMGDIRLAGTFAYKWTQIKKRLPGIYLLSNTFI"
BASE COUNT         7820 a         4125 c         5092 g         6617 t
ORIGIN      
        1 tattttgcta atccagctct gtttattcag cctatttttc tttttgaata tatcaagcgt
       61 tgtggcaaca tagtgatgac taatgaaaca acgacgatag acaacaaacg atcaaggtag
      121 tctgtacctg cctgtaccaa gatcacactt gttgtctgac ttaaacctaa cccatgtaat
      181 agctgaacga tcatactgga tcctgaggag gtgatcccgc caaataactg aacggtaatg
      241 atcgaagaaa cgatcgttcc aggtaccgac aaaatcaaag cgagtaataa cagtttcaag
      301 ctgtttttat ctttgccgag atatcttggc aaaatcaatc cagcaagcaa gcctgtgaga
      361 atttggattg gcgaataata cagagaaaaa atatctgtag tcactccact taaaataccg
      421 ctggacaatc ctgtcagcat tccaggtaca ggcccaagca atgcaccagc aaaaatcgtt
      481 ccgatagaat cgagatagat tggcaaacga agccataaag caatcgttcc tccaatataa
      541 ttgatcccaa tacacaaagc catcactgta agtacgcgag ttgccatttt gtttttattc
      601 attttgttag cccatcttta acctttccaa atctttcata atcgtttctt cttgtgcatt
      661 taaaagaacg gttaaaaact ttcggaaaaa aagacgagta tctacttttg tcataatttt
      721 actgttagca ggtttctgcc aaaattcata acgatcaacc aatgtttgtc cacgacttat
      781 tccttgagtt tccacagcag tgaagctttt gaaaccttca cagatggcct cctcgataaa
      841 ataagcaaca gctaacggat cattgatgac acatcctaaa attctttctt gtttccagtg
      901 gaagtcaaaa taaaaacgag tgatcgcttt tagatactct ccctcttcag gattcatttg
      961 acagcagtat tcgaggatag tcggtgtcaa gacgatttct cttgtcacat ctaacccaac
     1021 catttctatc gtttgtttga gattctcgaa tacataagaa gctgcttcag gatcacacca
     1081 gtaattgtat tcagcaactg gcgaacagtt accatggctt ttgtaagttc cacccatcga
     1141 gacaaaacgt tccatatgtt tcccaatatt tgggttgact ttcaaagcag aagcgatatt
     1201 ggtcaaagga cccaaagcaa tgactgatgt atttgtcttt tctttgaaat aatcagccaa
     1261 aaaatcaacg gcatggagag gttctgcctg ttttctcaag atcatcggga aatttgtttc
     1321 ccctaaacca tccataccat gagtgtcttg tgcactgatg aaaggttgct tcaaaggttt
     1381 ttccattcct tgataaacag gaatgtctaa acgatcacag cgttccaggc atttcagcac
     1441 attctgcgta cctatatctg cagggacatt cccacaaact acggtaatag caactacttc
     1501 gatatcaggg gatttgacag ctaatgataa agctaaagtg tcgtcgatcc ctggatcgca
     1561 atcaataatt acttttcgca ttatttccaa tctcctttct ttagagatac ttagtttttt
     1621 attctgggaa gtttccgaac cagtccaaga cgagcgtctt gattataatg cacgaaatta
     1681 gtatactggc ttttattgcg aatgtaaatg ctctcttaca agtaaatcta ttgaggagaa
     1741 ctttaagtaa atgatacaat gaaaaagaaa tggaatttac gtgtgccgaa aataaagaat
     1801 cctatggatc ggtacattgg ataatagata gattatagtt tggcagaaag cggcgggtgt
     1861 acaatggtta ttttttattt cattcttatt ctgataatta tagggatcag ttaccatttt
     1921 ctttcttatt tttatgcaaa gaaattagta agagcgggag tacagagagg atatgactgg
     1981 tatgaagaca ctggtcatcg tttgatggac cctgctgcag tcacgtcagt agaaaaaaaa
     2041 cgacaaaaat tagaagaaga gtgtgaaagc ttttgggagc agggaacacc caaaacaatc
     2101 aaaagttatg acgggttgaa actagctggt cagatgttca tccatccaaa taagcagaat
     2161 aaatgggtca tttgcgtaca tgattaccga agcacaggga aaagagacat gtctcatata
     2221 ggtaaaagat atgcagagaa aggattcaac gttcttgtac ctgatttacg tgcgcacgga
     2281 gaaagtgaag gagaaatcat cggaatggga tggctagatc ggctagattt aattgcctgg
     2341 atccaactca tcttagatga acagccgaat gcgtccatta ttttacacgg cggatcaatg
     2401 ggagcttcta cgatcatgat ggcaagtggt gaaaaacttc catcagcggt caaaggattt
     2461 attttagaca gcggatatgt ttctgtttat gcagaattcc gatatatgtt aagtaaaatc
     2521 actgtctttc ctaaaaaaat ggtcatgaga tatgcgaatc attatgccca gaaatacgcc
     2581 ggttactcct taaagcaagc atcagctacg agacagcttg gcagcaatca tctgccttta
     2641 ttagtcatcc atggtgaaag agatcatttt gtccctacag aagcagcgta cacgattcaa
     2701 aatgctacgg caggggataa agcactgctg cttgttccgg aagcagaaca cttggaagca
     2761 tcgatgaaag atccgaaaac ctattggaca gtgatttttt catttattga acaaagaata
     2821 acgatgaatt aattttctct tcttttttgt aagtaattcg aggataaata attgtttata
     2881 gatcaggaga ctgctaaaat aaggtaggaa taaaaaaata tcagttattt gaggagtgcg
     2941 gcatatggaa atcaaagaag aaaaaatcgt cttgctttat tcaatgatga acaacaagag
     3001 atcggagaaa tgacatggtc agatgcgggc ccagacatca tgatcgttga ccatacattt
     3061 gtagatccag catatcgtgg tcaaaagtta gctgaaaagc tagtgtatac tggagtagaa
     3121 ttagcaagac gagacgggaa aaagatcatt cctttatgcc cttatgcaaa aaaagagttt
     3181 gaaaagaaac cagaatatca agacgtctta cgtcagtcat aagaataaca gctgaaagtt
     3241 ttgaactttc agctgttatt ccatttatat agagttgtca cggactttta tctatgataa
     3301 agttaaagag acgatatctt ttgggaagga ggctgcgata tgtataattt aattttggga
     3361 atcgtgatcg ttttatcgat tgttatggtc attgcgatta tgatgcagcc aagcaagcaa
     3421 aatagtgcag cgagtgcatt taccggcggt gcggatcaac tattcggcaa acaaaaagct
     3481 cgcggctttg aagctgtcat gcagcgatca actgcagtta tgggagctat ctggatgatc
     3541 ttattatttg tcctagcata tttatcttcg aagtagttga ataagcctct cgcaaaacgg
     3601 cgggcggctt tttttattgc aaagagaacg cttaagaaga agttatgaaa gaaactatgg
     3661 taaaatgagg cgaaagaggt gagacgagtg agacaattac caaaacccct ttatgcaaaa
     3721 catggaaagc gagcggtttt gctgcttcac gcttactcag gaagtccaaa cgatgttcga
     3781 atgctcgcac gatttttgga aaaagcagat tatacagttt atgcgccgct ttttaaagga
     3841 cacggaacaa tggagccata tgatatcttg caagaaaaag cagaaagctg gtgggcagac
     3901 actaaaaaag ccatccattt tttacagtct gagcagtttt ctgatattgc cgtattagga
     3961 ttatcaatgg gcggcatctt tgctgtacga gcactagaag aagaatcagt gattggcggc
     4021 ggttttttct gttcgccttt gtctcctgta aaaacaaacg tgcctgaaaa ctttgaaaaa
     4081 tacgtacgtc aagtgctgaa gacagcaggt aaatcagaga aagaaatcaa tgaaaaagca
     4141 gttgcttacc gctcgttagc tgaacaacaa ttaatggata tacaagatca ggcagcaatc
     4201 gtagaaagta ggttgtcaga tatccaacag ccgatatttt tagctcaagc tgggaaagat
     4261 gaaatgatcg accctaatgg cgtatttgaa actgcacgca agttgagccg tcagcgagtg
     4321 acacttcaat ggtatcctga aagtggtcat gtgattacag ttggtacagc aagacgcgaa
     4381 ttagaaaaag acgtcttgga atttttagaa aaattacctt ggaatgagga ataaatatga
     4441 caaaagaaac gataaaagag aaaattctct ttttcatgga aagcagtcgc aaacgcagtt
     4501 tttctatgga agaaatcgct gaaggtttag ggttccaaaa aagcgatgat tttaaattac
     4561 tagtacaaac gattgctcaa atggaaagag aacagagtat agttttcaat aaaaaaggaa
     4621 aagtgaaact tcctttaaaa ccaatcctga tcgaaggaac atttcgagca aatgaacgag
     4681 gatttggatt tgtaacgatt gatcccgaag aagatgacat ctatatccca aaagaagcga
     4741 ctggttttgc aatggatgga gacaccgtag caatcgatat catgaagcga gcaaatacag
     4801 atatggatcg cggagcagag gggaaagtag tcgagattcg agaccgggcg actactcagt
     4861 tagcagggga attcgttgct tattcagaag aagaaataca agaaacagat ctttacggcg
     4921 ttgttatccc gaaagataga aagctcaacc aatttaaagt atatgcagca gcagagggag
     4981 ttcgtccagt tgacggaagt attgtgctga tcgaactgac ccattaccct gaaaaagggt
     5041 atgcgactag tttagaaggg ataatcaagc aagtgattgg tcataagaat gaccctggca
     5101 tggatatcct ctcaattgtc gtggctaatg gtatccctac gaaatttcct gatgatgtat
     5161 tgtctgaagc agatgaagtt ccagatcaaa tcagcgaaaa ggatataact ggacgtagag
     5221 atttaagaaa tcagctcatt gttacgattg atggagaaga tgcaaaagat ctagatgatg
     5281 cagttacggt taaaaaatta gataacggta attattttct tggagtacac attgcagatg
     5341 tttcttacta tgtgacacaa ggcagtcaat tggacagaga agcatatgaa agagggacaa
     5401 gtgtatattt gactgatcga gtaattccga tgatcccgca acgtttatcg aatggtatct
     5461 gttcactgaa tccccatgtt ccaaggctga ccatgagttg cgaaatggag attgatccaa
     5521 atggacaagt agtctctcat gatattttcc caagtgtgat ccaaacaaca gaacggatga
     5581 cctacacagc tgtcaatcaa atcttagaag atcaagacga agaaacgatg caacgctatg
     5641 ctcagctcgt acctatgttc caagaaatgg gtgaattgca ccgaatcctt gaaacgatgc
     5701 gaatcaaacg tggcgcgatt tcttttgagg atcgcgaagc gaaaatcctt gttgatgctg
     5761 aaggacaccc aaatgacatc cagctaagaa gcagaggaat tggtgaacgc ttgatcgaat
     5821 ctttcatgct tgcggccaat gaaacggtag ctgaacatta taataaatta aatctgccgt
     5881 ttatttaccg aatccatgaa cagccaaaag aagaaaaaat gcagcgcttc tttgattttg
     5941 cttcagcttt gggcattctg gtccgaggaa cgaaaggaac gatcacacca aaagatttac
     6001 agcatgtgat cgaaggagta gaagacaaac cagaagctgc agttatcaat actatgttgc
     6061 taagaagcat gcaacaagca cgctattcag aagacaattt tgggcattat ggcttagcgg
     6121 cagattacta cacacacttt acatctccta ttcgacgcta tcccgatcta atcgtccatc
     6181 gtctgatccg ttcttacagt gaagataaaa gtgaaagcaa tcaaagttcg tgggctgcgg
     6241 aacttcctga aattgcagat catagttcta agatggaacg tcgtgcagta gaaacagaac
     6301 gtgaagtaga ttccatgaag aaagcagaat tcatgatgga caaagtggga gaagaattcg
     6361 atgggatcat cagctctgtt gtgaaattcg gcctgtttat cgaactgccg aatacagtag
     6421 agggattgat ccatatcaat gaattgaaac aggactactt ccattttgtt gaaaatcatt
     6481 tagctcttgt aggtgaaaga actggtctga cttttaaaat cggacagaaa gtgcgagtaa
     6541 aagtagtcaa agctgatcca gatgaacgag cagtagattt tgaacttgtt tccgcagaag
     6601 aggttacagc gttggaacgg ccaaaaacac gaaatggaaa atcaggaaaa cgcgaaggaa
     6661 aacaagcagg aaaacgccca gaaagaaatg gcaagaagaa caaacgatat agcgatagta
     6721 agcaaacgtt cggtaagaaa aaagggaaga agccatttta caaaggtgtt aaaaagaaga
     6781 aaaagaaaaa ataaaatgag ttggaggaaa cagctatgcc aaaaggcgag ggaaaattaa
     6841 ttgcacaaaa caagaaagct cgccatgatt attcgatcat cgacacgatg gaagcaggga
     6901 tggtcttgca aggaaccgag atcaagtcga tacgaaacag ccggatcaat ctaaaagatg
     6961 gatttattcg cgtccgcaac ggagaagctt tcttgcataa tgttcatatc agtccttatg
     7021 aacaaggaaa tatttttaat catgatccgt tgcgcacgag aaagttatta ttacacaaaa
     7081 aacaaatcat ccggcttgaa aatgaattga aaaatactgg aatcactgtt gttcctttaa
     7141 aagtctatat tcgtaacggc tatgccaagg tattgattgg tctggcgaaa gggaaaaaat
     7201 cttatgataa acgggaagat ttgaaacgaa aagatatcga tcgacaaatt gatcgaacat
     7261 taaaaaattt ctctagataa tttcattatc ctttttcgca tattcggtgc ttttgctttt
     7321 acttaatgat aaaatttgtt agcatttaat ctgataaaac atgattatca taggtttttt
     7381 cttagatcag gagcaccgtg tataaagaaa aattcgcttc gtttttgact gaaataaaaa
     7441 agtgtctaat tttcatgaaa atgttttgaa ttttctgttt catggtggta tgataccgtg
     7501 tggttagaaa ccgattggaa aaaaccagat acgcacatga attgatttta tgtgaatttc
     7561 ggggaaaaga ggtgaaatgg attggatgaa cgctcgctaa cgttccacat tggaccaatt
     7621 tggtttgatg gtacagtttg tataatggtg ttactgacct gtttgattgt tttcttctta
     7681 gcttactttt ttacaagaaa tcttaagttg aaaccaacag gcaaacaaaa tgcgatagaa
     7741 tgggtcattg attttagtcg aggaatcgta acagataatc tgcctagaaa agaattgagc
     7801 aatttccatt tgttggcatt tacattgttt ttatttgttt ttgttgcaaa caacatcggt
     7861 ttagtaacaa aaatcgtttt acctaacgaa acaacacttt ggaaaagccc gacagcagac
     7921 ccgtttgtta ctttaacttt ggcatttata atgatcttac ttactcactt attcggggtg
     7981 aaaaagttag gcttcaaagg atatttcgta aattcgttct tgaaacccta tagttttatg
     8041 tttccgatga aactgattga agaatttaca aacttattaa cacttgcttt acgtctttat
     8101 gggaatattt atgcggggga agttttgcta accttgattg caaaaatgat gacaagctta
     8161 ggctggttct cattaccatt agcaattcca ttagagatgg tctggatcgc gttctccttg
     8221 tttattggga gcatccaagc atttgtcttt gtcactttgt caatggttta tatgagccat
     8281 aagattgaag tagaagaata atactcggtt aaaaaacaaa ctactattta tctattttag
     8341 gaggaaaaca attatgaatt atatcgcagc agcaatcgca atcatgggag cagcaatcgg
     8401 agccggttat ggtaacggtc aagttatctc taaaacaatc gaatcaatgg ctcgccaacc
     8461 tgaaatgtct ggtcaattcc gtacaacaat gtttatcggg gtagctctag ttgaagctgt
     8521 tcctatctta ggggtagtta tcgccttgat tctagttttt gccgtttaat tgaatcagta
     8581 ttaaggcaga aacaacatcg tttgttactg cttttttaca tggaaactag aaatactcca
     8641 aagaaaggaa ggctcgccta tgctgaatca attggcaatt gcagaagttg gcaatgcgat
     8701 gttaggtaat atcatcgttg tcagcggctc atttttgata ctactggctc tcttgaagca
     8761 ctttgcttgg ggaccaatca gcgatatttt gaaaaaacgt gaagacaaga tcgccaatga
     8821 tttagattct gcagaacaat ctcgcatcaa ctcagcgaaa atggaacaag aacgcgaaca
     8881 acaattgtta gcctctcgtt ctgatgcagc tgatatcatc aaaaatgcga aagaaagtgg
     8941 agaattaagc cgccaaaata ttttgaagga tgctcaagaa gaagcagctc gtctaaaaag
     9001 caaagcccaa gctgatatca ctgtagaacg tgattcagcg ctgaactctg taaaagacga
     9061 cgttgcagaa ctctctcttc aaatcgcgga aaaaatcttg aacaaagaat tatctccaga
     9121 aatgcatgaa tcattaatca atcaatacat tgaaggtcta ggttcttcaa atgaaactag
     9181 ataaatatac agtaggaaga cgttacggga aagctttatt tgaactggcg atcgattcaa
     9241 atcaagcaga agaaatctat caagatctcg taagtttacg tcaaatctat gaacaagtac
     9301 ctggattagg gaatatgtta agtgatgttc gtctagaacc tcatgaaaaa cgagaaatca
     9361 tggacaagct tgtcagcggt tatgatggga tcgttaaaaa ctttttagaa gttgtttatg
     9421 agtataaccg aatggatgac cttttgttca tgatcgaaga atatgaacgt cgatatgatg
     9481 aacatcaagg gttactattg ggaagtgtca caacagcagt cccactttca gacgaacaac
     9541 gaatacaatt agaaaagaat gttgcaaaaa caatggacta tcaatcagtt gaattaaaac
     9601 aaatcgttga ttcttctatt attggtggcg cgattgttga agccaaccat cgagtaatcg
     9661 acggaagcat tcgcacgcaa ttagaaaaaa tgcgtaatca attaaacaga tagtacaaag
     9721 aggtaggtga atcgaatggc catcaaagca gaagaaatta gtgccttgat taaagaacaa
     9781 attgaaaatt atcaaaacgt gctttcagtc gaagaaatcg gtaccgtaac ttatgtaggt
     9841 gacgggatcg ctcgtgcaca tggtttagaa aacgcgatga gtggtgagtt gcttgaattt
     9901 tcaaacggct catacggaat ggcgcaaaac ttagagtcaa atgatgtagg tatcattatc
     9961 cttggcgatt tcgagtccat tcgtgaagga gataaagtaa aacgaacagg taagatcatg
    10021 gaagttccag ttggagaggc cttgatcggt cgggtagtca atccgctagg tcaaccaatc
    10081 gacggactag gtgaaatcgt tactgacaaa gctcgtccag tagaagcgat ggcaccaggt
    10141 gttatgcaac gtaaatctgt taacgaacca atgcaaacag ggctaaaagc gatcgacgcc
    10201 cttgtgccaa tcggacgcgg acaacgtgaa ttagtcatcg gtgaccgtaa aacagggaaa
    10261 acttctattg cgatcgatac gatcatcaac caaaaaggtc aagatatgat ctgtatctat
    10321 gtagcaatcg gacaaaaaga ttctacagtt cgtacacaag ttgaaacatt gaaaaaatat
    10381 ggcgcaatgg attacacaat cgttgtgaat gccggtgcgt ctcaaccagc accattgctt
    10441 tatatcgcac catatgctgg tactgcaatg ggtgaagaat tcatgtacaa cggtaaacat
    10501 gtattgatca tttttgatga tctttcaaaa caagctgttg cttatcgtga actttccttg
    10561 ctacttcgcc gtccaccagg tcgtgaagct tatcctgggg atgttttcta cttgcactca
    10621 cgtttattag aacgtgcagc aaaattaagt gatgatttag gtggcggttc aatgactgcc
    10681 ttaccatttg ttgaaacaca agctggagat atctctgctt atatcccaac aaacgttatt
    10741 tcgatcactg atggacaaat cttcttagaa agcgacttgt tctacgcagg tactcgtcca
    10801 gcggttgatg ccggactatc tgtatctcgt gtaggaggtt ctgcgcaaat caaagcaatg
    10861 aaaaaagttg ctgggacttt acgcctagac ttagcaagtt accgtgaatt agaagcattt
    10921 acacaattcg gttctgactt ggatgcagca acacaagcaa aactaaatcg tggacgccgt
    10981 acagtagaaa tcttgaaaca aaaattgcat gcaccgctag ctgttgaaaa acaagtagtg
    11041 attttgtatg ctttgacaca tggattctta gatagtatcc ctgtagacag tattttagac
    11101 ttcgaacatg aattattcga atatctggat accaatcatt cagatatctt tgaaacaatc
    11161 cgtacaacaa aagatcttcc agaagaagaa gcgttgaaca gtgcgattca ggaatataaa
    11221 gacatgttct tagctacaaa aggaagtaat tcctctacag aagataaatt gaaatccatt
    11281 caaaatgcat agtgaggtga gatgaatggg tgcttcatta aatgaaatca agacacgtat
    11341 cgcttcaacg aaaaaaacga gccaaatcac gcgggcaatg cagatggtgt ctgcttctaa
    11401 gttgacaaaa tctgaagctt cttcacagaa gtttcaggtt tatgcaacaa aagtaagaga
    11461 aatcgttacg catttgactg ctactcagtt aaatgatatt gcctcagaaa atcctagagg
    11521 ggatatcaat tacaacagca tgctgctcag ccgtcctgtg aagaaaactg gttatatcgt
    11581 catcactgca gatggcggtt tagtcggtgg atataacagc tcgatattga aacaaacgat
    11641 gtctatttta gaagaagacc accaatcacc cgatgattac gtgatgatcg caattggcgg
    11701 aactggtgca gacttcttta aagcacgcgg tatcaatcta gcatatgagc tgcgcaatct
    11761 atctgatcag ccaagctttg atgaagtccg caaaattgta aatatggcaa caactatgtt
    11821 ccaaaacgaa gtattcgatg aattatacgt atgttataac catcatatca attcgctaac
    11881 tagtcagttt cgtgtagaaa aaatgctgcc aatctcagac ttagatccag aagaagcaac
    11941 gactttcgaa caagaatata tttttgaacc ttcaaaagaa gaaatcttgt ctcagttatt
    12001 gcctcagtat gctgaaagtt tgatctacgg tgcgatcgtt gacgccaaaa cagcagaaca
    12061 tgctgctggt atgacagcaa tgaaaacagc aactgataat gctgctaata tcattgatga
    12121 gctgacggtt tcttataacc gtgcaagaca aggggctatt acccaagaaa ttaccgaaat
    12181 tgttgccgga gcttcggcac tagaatagta ttgagattgg aggaaaaaag atgagttcag
    12241 gcaagattgt tcaagtaatc ggtcccgttg tcgacgtgga attttcttta gaccaatcct
    12301 taccagatat caacaacgca ttagttgttt ataaaaatga cgaaaataaa tcaaaagttg
    12361 ttcttgaagc agcgttagaa ttaggggacg gagtgatccg gaccattgcg atggaatcaa
    12421 cagatggttt acaaagagga atggaagtca ttgatacagg caaagcaatc tctgttcctg
    12481 taggtaaaga aacattaggt cgcgtattca acgtactagg agatacgatc gatttagaaa
    12541 cacctttccc agaagatgcg gaaagaagcg aaattcataa aaaagcacca gcctttgacg
    12601 aattaagtac aagtacagaa attttggaaa cagggatcaa agttatcgat ttgcttgccc
    12661 catatttaaa aggtgggaaa gtcggactat tcggtggtgc cggtgttggt aaaaccgtac
    12721 tgatccaaga actgatccat aatatcgccc aagaacatgg tggtatttct gtatttaccg
    12781 gtgtaggtga acgtactcgt gaaggtaatg acttgtatta tgaaatgaaa gattcaggag
    12841 ttatcgaaaa aacagccatg gtgttcggac aaatgaacga accaccaggt gcacgtatgc
    12901 gtgttgcttt gactggtttg acgattgcgg aatatttccg tgatgtagaa ggtcaagatg
    12961 tactgttgtt tatcgacaac attttccgtt tcactcaagc tggatctgaa gtatcagcct
    13021 tgttaggacg gatgccttct gcggttggtt atcaaccaac attggcaaca gaaatgggtc
    13081 aattgcaaga acgtatcaca tctacgaaaa aaggttcgat cacatcgatc caagcaatct
    13141 atgtgccagc cgatgactac actgacccgg cgccggcaac agcattcgcc catttggatg
    13201 cgacaaccaa cttggaacgt aaattaacag aacaagggat ttatccagcg gtagatccat
    13261 tggcttcttc ttcaagtgct ttagcacctg aaatcgtggg agaagaacat tataaagtag
    13321 caacagaagt ccaacacgta ttgcaacgat atcgtgaatt acaagatatc attgctatct
    13381 taggtatgga tgaattatcc gatcaagaaa aagtgttagt ttctcgtgcc cgcagagtcc
    13441 aattcttctt gtcacaaaac tttaacgtgg ctgaacaatt tactggtctt ccaggttcat
    13501 atgtccctgt agaagaaaca gtgaaaggat tccgcgaaat cttggaaggc aaatacgatg
    13561 atcttcctga agaagctttc cgaagtgttg gccgaatcga agacgtcgta gaaaaagcga
    13621 aaacactagg ctactagaaa ggggtgcccc atggatcaat atttaacagt aaatgtggta
    13681 actcctgccg gtttggtcta tgatcaccat gcagctatcg tcgttgcacg tacgacagct
    13741 ggtgagcttg ggattttgcc taaacatgca ccaatcatcg ttccattgac gattgatgaa
    13801 gttcgtgtaa aacgaacaga ttcagatacc cacgtcgatt ggatcgctgt taatggcgga
    13861 atcatggaag ttcgtgataa tgttgtttca atcgttgctg atagtgcgga acgtgaacgt
    13921 gatatcgatg tatctcgtgc ggaacgtgca aaacaacgcg cagaacgcca aatcgaagaa
    13981 gcaaaagcaa aacaagatac gaacgaattg aaacgggcaa ctgttgcgtt gcaccgagca
    14041 atcaatcgta tcaaagtatc taagcactca taaaatgaga tgcggatgtt tatccgtgtt
    14101 taagaacagt aaaaagaggt tatgacagaa gtggtcagct tcaagacata agaaggaatt
    14161 tacgaaaatt gcttctcaaa tttttgtgaa atctcagctt atttttcgaa gaagctactt
    14221 ctggaacacc gtatatcaga ggttgtgaaa tcagcgtttt gtcctgagta ttagagaaac
    14281 aaatggaaaa tagttcctca tattttgccg ttttttgagc taataccgag ggtcagatga
    14341 ttgaacaccg tttatttgga ataagggact gcgacaagac ttttgtctca gtcccttttt
    14401 ttgcatattt ttagcattta tttcctaaaa aatgtaaggg gattcctata tttttaagta
    14461 tacttgtttt tccttttata cattttatgg tattatcatt ttattagtta ttataaaaca
    14521 atcgttagaa aggacgtcat tatgcaagta tacggaattg atgcggtgct tcgaatcgtg
    14581 agtcatttgg cgtttatcta cttagccttc tggtctttac gttcgttacg cattgaaact
    14641 tttttcagac caatgcataa tacgcaaatt agaatggcaa tcgtactttt ttcaattttt
    14701 ttagggtaca ctgcaagtaa ttttttctta gaggttatcg ctttatgccg aaatcttttc
    14761 gttagcctgt aaattttaaa aaaaggtact attttaaaag caaggatgtt ataatagaaa
    14821 agattttgag taagtgtatg ctcattggaa ttttttggag ggaacaacat ggaagagatc
    14881 atcgtaagag gtggcaatca attaaatgga acagtaagaa ttgaaggagc taaaaatgct
    14941 gttttgccta ttttagctgc tagtttgtta gcagaagaag gtattacgac attagacaac
    15001 gttccgattc tttctgatgt cttcactatg aatcaagtga ttcgtcactt aaacgtagat
    15061 gtagattttg atgaacaaaa gaatcaagta acaatcgacg cttcaagaca attagaaatc
    15121 gaagcgcctt atgagtatgt tagtcaaatg cgtgcttcaa tcgttgtgat gggtccgcta
    15181 cttgccagaa atggacatgc aaaagtagct atgcctggtg gatgtgcgat tggtaaacga
    15241 ccaatcgatt tgcatttaaa aggatttcaa gctttaggag caaaaattat tcaaaaaaac
    15301 ggctatatcg aagcaattgc ggatgaattg atcggtaaca cgatttattt agatttccct
    15361 agtgtaggtg ctactcaaaa tatcatgatg gctgccgtaa aagcaaaagg aacaaccatc
    15421 attgaaaacg tagctcgcga accagaaatc gttgatttag caaacatttt gaataaaatg
    15481 ggcgctcaag tctatggagc tggtactgaa acaatgcgta ttgaaggcgt ggatcattta
    15541 catgcagtca accactcaat cgtacaagat cgtatcgaag caggtacctt tatggttgct
    15601 gctgcaatga cacaaggcaa tgtgctgatt gcagatgcta tctctgaaca taaccgccca
    15661 ttgatttcta aattgatcga aatgggtgca gaaatcattg aagaagaagg cggagtccgt
    15721 gtcatcggac caaaacatat cttacctaca gatgtaaaaa cgatgcctca tcctggtttc
    15781 cctacagata tgcaagctca aatgacagct atccaattag ttgcagaagg tacaagtgtg
    15841 gtgactgaaa cagtgtttga aaatcgtttc caacatttag aagagatgcg ccgtatgaac
    15901 gctcatgtca aaatcgacgg aaatgtagca atcatggatg gaaaccatga attgcaaggt
    15961 gcagaagtat atgcaacaga cttgcgggca gcagcagcat tagttttagc tggcttgaaa
    16021 gcaaatggaa tcacacgtgt gcgtaacttg aattatctag accgtggata ttataatttc
    16081 catatcaaac tacagcaatt aggtgcagac gtcgaacgtg tagacatgga tcaaacttct
    16141 gctgaaaaaa cagcacaaac gattgcttaa ggaagtggct gaatgagtaa ccaacgatat
    16201 atcttattaa ctttgataaa gattttagtg gtgatcttat tgcttatcct tctttttgtg
    16261 gccggaacga tgatcggata tggtgtcatc ggtggcggca atccatttaa agtattccag
    16321 ccaagtttgt ggattcatat tcgagacttt tttcattgat aaataagaat cacagtggtt
    16381 ctagtcgata tgaagtgagc catgaagcag aacatgataa aagaaaacag aagggaacgt
    16441 tgacgttagt cgcgatccct ttttttagta aaagaaaaga aggaatctaa ttgatgaaga
    16501 agatattgat ttatttagtt agaggatatc agcgctttat ttcgcctgca tttccaccta
    16561 gctgccgtta ttacccaacc tgttccaatt atatgataaa agcaattcaa acccatggtg
    16621 cgctaaaagg gacggtaatg gggactgcac ggatcttacg ctgtcatcct tttgtcaaag
    16681 gcggtatcga ttatgtacca ttgacattcc gattaacgcg aaataagaaa gataaaaaag
    16741 aaccagatta taaaaaggtt gtgaaaaata cgggtagcac tgagcgataa agaaaaagag
    16801 gaaatttatt gtcaaagtaa caactccgca actacttata tgggggacaa aaaatgatcg
    16861 aagaactaaa caagaaagat ttaccatggt ccttgttatt agatgcagat cctgataaag
    16921 aaaaagttca agtatatgtt tccagaggga gtggctggat atggaaagaa aaagaaaaaa
    16981 caataggtgt actgatctat gtggcaaggg aaaaagaata cgaaatcgtc aatgtagcag
    17041 taaccccaac gtatcaagga aaggggattg gcggaaaatt acttgagaca gcttttcaga
    17101 agctttcaca gctagcttca aaccaaactc ggatcattat acgtactggc actactagta
    17161 gcgctgcgtt acacctctat caaaaaatgg gctatgtgga gattggtcga gtcaaagact
    17221 attttatcca tcattactct gagcccattt ttgaaaatgg agatcaatta agggatcaag
    17281 tgattttagc aattcactta cctaaaaata gctttaacta ataaactttc aattcgagaa
    17341 aatgctttca aatgctaaat agatacatta caatagcttt agcaaacaaa aaggagaata
    17401 tttttatggg aatattagtt tttgattttg gtggatcggc tgtcaaatat ggttgttggg
    17461 atggcaaaga gattaaaggt aagggacaat ttgcaacgcc tgaatcttgg gaagaaatga
    17521 aaacgcaatt atttcaagtt tataaaaaaa tactcgtttc ttttgaagtc gaaggaattg
    17581 gaatcagctc tcctggagta gtgaataatg agaaacaggt gattgaggga atcagtgcga
    17641 ttccttatat tcatggattt aatattttcc gagatttgga aactctgttt caactcccag
    17701 taacgattga aaatgacgcc aactgtgccg gaatggctga attttatgaa ggtgctgccc
    17761 gtgattatca agatgttgct tttgttgtgg caggaactgg gattggcggg gcgttgttca
    17821 cgaaaggaca aataaataaa ggggcacatc tttacggtgg agaatttggg ttgatgttct
    17881 tagatggcga taagacattc agtaaacttg gtacagcggt acagatggct tggcgttatt
    17941 gtgaacgcaa aggtctcgat aaaaatgctt ataccggaaa agatgtcttt gaattagcag
    18001 aaactggaga tgcaatagca aaagaagaag ttgagagttt ttatacgtat cttacaaagg
    18061 gattattcag tattcaattt tcgtttgatc cagaagtgat cgtattaggc ggcggggttt
    18121 ctgcaaaaga agggctcatt gatgagatca aaagccgaat gaagaagctg acagaacaat
    18181 tcgatctgca tgatttcgaa ccgcagattt tattatgtga gtacagaaac gatgctaatc
    18241 ttataggtgc agcagcaaac tatctcgctg tacgtcaagg agagaattaa gagctttaga
    18301 gaaggtgcag cttgcataaa agaagagaat gaaatgaata ggagattttt acctaaggaa
    18361 tgttttattt gctgcagtat gataaaatat ctgagaggtg aaaatgatgt caaaaaaaaa
    18421 taaagatatt gaagtgcgta tagaagaagt gaaaaaagat atcaaaggta agaattatga
    18481 agtcactcag ttatttatag ggaaaaaaat gattggtgag atcttagcct atgggccaaa
    18541 agaatatgaa attttctttg gtgaagaaga ttttggaaaa gaaaaaagtc ttgaaaatgc
    18601 gatagaaaca gtgattcgac actggaatct gcacgaataa aaaaatatca aaaaaacttt
    18661 caataaaggg ttgcaaaaat ctggaaaatt aggtattata actaagtcag gttgatacaa
    18721 acctttcgga ggagtagcga agtggctaaa cgcgacggac tgtaaatccg ttccttaggg
    18781 ttcagtggtt cgaatccact ctcctccatt tcattggggt atagccaagc ggtaaggcaa
    18841 gggactttga ctccctcatg cgttggttcg aatccagcta ccccagtata ccacaatcgt
    18901 aagctctcgt tagttcgaga gctctttttt tttgctttgc taccttgttc cttgaagatt
    18961 ctgctgaatt aagatagagt taagttaact acaagaattg gagggatcca catgaaatgg
    19021 aaagaaaaag tagacgaagc agctgaaaag ttatatgatt tggtcaaatc agaaaaatac
    19081 aatattgaag tgaatattcc gaaaaaaggc ggaaaagcgg tccaggtaaa atcaaaacgc
    19141 ccaacgaatc atacaaaaaa atggatggct aaaaaccgct aataataaca aaagatccat
    19201 aagtcggcat tttcatcgat tttagggtct tttgttattt tctaggttga acatatctaa
    19261 aaaattgttt ctgacaatag gagtagggag aacgatgtgt gtctaaatcc tctgttgatg
    19321 gatagaaacc tttatctttt tcagttgtga atcaggtata taccagttat aatagaagaa
    19381 acgaaaggac gggtgtacgt tatgtcgaat caattacctg tatatataca gattcatgac
    19441 caattaaaaa atgaaatcga acaaggtata tggaaagtcg gagaccgtct tccttcagaa
    19501 agagaattag cagtgaaatt caatgtcagc cgtatgacgt tgagacaagc aattcaaaac
    19561 ttggcagatg aaggaatctt agaaagaaag atcggttcgg gtacgtatgt tgcgcgagaa
    19621 aaagtacaag aaaaaatgtc tggtgcaaca agttttacag aaattatgga atcacaaaat
    19681 cgagtaccgt ctagtcggac aatctcttat ttcttgactt cgccaagctc aagtgaaatg
    19741 gaaaaactaa acttgagtaa agatgacacg atcttgcgaa tggaacgtat tcgtttcgca
    19801 gatgatgtcc ctatttgttt tgaagttgcc agtgttccac aaaagctgat cgatggctac
    19861 agcaaagcag agattactga atcgttgtat cgcacgctag aagaaaaagg cgggaaaaag
    19921 atcggtccag cgaatcaaac gattactgct gtgttggctt ctgagaaaat tgctgactat
    19981 ttagaggtaa aacgaagaga tgcagttctt cgtttgcgcc agatttctta ttttgaagac
    20041 ggtacgccgt ttgagtatgt gcgtacgcaa tacgtaggaa atcgttttga gttttatttg
    20101 gaaaaataaa aaacaggtga tccctgattc cttattagaa ataaaagaga atcagaatca
    20161 cctgttttta tatatgatca gttatcagtt gctcgtgata agaaacagaa ccctcttcaa
    20221 attggacttg tccgttcagc agctcaatga tggattcttt aaagtggtta gcactttttt
    20281 catctacagc acagatgacg ctaacttgat cagtatattg gatttctttt ataaaaaaat
    20341 gttggagttc aagataattc tgtaattttc ctagttgcgg atacgtgatc atcacagaga
    20401 tctcctgttg caaggtacct tctacgattc caatgtcaga caatgcttga gagaccgcat
    20461 gagtgtatgc tcgtattaat ccgcctgtgc cgagtttcgt tcctccaaaa tatcgagtga
    20521 ctactgcagc tacattgatc agttgatttt ttttgaggac ttccaacatc ggtacgcccg
    20581 ccgttccact tggttctcca tcatcgctgc ttcgctggat ttcatttttt tctccaatga
    20641 tgaaggcgct gcagttatgg ttcgctttcc aatgttcttt ttttatttct tgaatgaaat
    20701 tttttgcttg gtcctctgat tctattcgtc taagagaaca gataaagcgt gattttttga
    20761 tctcaatctc actttgtcca ttttctttta ttgtacgata gcgctcgatc atcttgtcac
    20821 ctcttttttt cattttcttt attcagtata aataaagttc taggttgttt caacactgta
    20881 acggttgcgc aattgctgta gtatgcgata ataaagacaa aggcaggtgg atctggggat
    20941 gcaggaacga atgaaaaagt acgatgcaat tacgcattat ttgaagaaca atggcggctc
    21001 tcaagtaacg ttgaccttta cccaatttga cgaactgctg tttcccagta acggacttcc
    21061 caaaacagca agggaaagta cagattggtg ggcaaatgat tataaacacc ctgaaaaagg
    21121 tgcctatggc tggataaatg caggctatga agtagttgtc atcaatttgg acaaagaata
    21181 tgtcgtgttc aataaattag tgaaatctag ttggctattt gattaaataa accgcgttta
    21241 gaaaacgttg acaaatttct ttctttttat ataataaagt aacagacgcg aagaaaacgt
    21301 ttgcgtagtt tgttttaaaa aggagagaaa aatatggcta aaaaaacaat catgcttgta
    21361 tgttcggctg gtatgagcac aagtttacta gtaacaaaaa tgcaaaaagc tgctgaagca
    21421 aaaggaatcg actctgatat tttcgctgtg tccgcttctg acgcagataa caatcttgca
    21481 aataaagacg tggatgtgtt gttattaggc ccacaagttc gctttatgaa agctgatttt
    21541 gagaaacgtc tggaaccaaa aggcattcct ttagatgtca tcaatatggc tgattatggt
    21601 atgatgaatg gcgaaaaagt gttagatcaa gcaatcgcgc tcataggtga ataaatagaa
    21661 cagtataact atcgaacaag cgatccaaaa aatagatcgc ttgttttttc gtatattttt
    21721 ttagggcgaa taatatgaat catttttggg gtagaaggct tctgacgaga gatattaaag
    21781 caatagactg tgaggaggta aatttaccaa attatgagaa gatcgcagca gtggaacgtt
    21841 tgggcaactg gattctttgt catcgctgtg gaatgaggac gtccgtcatt gttggacagc
    21901 ttgcagatta cggttatttt tgtacacatt gtctatattt agggtgatgc gacactcaac
    21961 aagatttata tttgtttgat cagcctgaag caaaacctcg agaagtcgtc tttttttgga
    22021 caggacagct tactgaaaaa caaacggaaa tcgcaaagag aatactttgc cattcagaaa
    22081 aaagacatca tcttatttgg gctgtaacag gtgcagggaa aacagagatg ctttatccta
    22141 ttttagtgga aactttaaaa gctggaggaa gagtagcgat ttgtacaccg cgagtcgatg
    22201 tttgtaatga attgttttta cgctatcgtt atgtttttcc agaagaaaaa atcacgttgc
    22261 tccatgggaa tacagcaacg gcttatacct ttacttcttt tgttatctgt acgattcatc
    22321 agctataccg tttttatcgg tcctttgatt taatagtgat cgatgagatc gatgcgtttc
    22381 cttataacgg ggatgctggg ctagctcacg ctgtgcaaac agcaatcaga tcaaacggcc
    22441 gattcatcta cttaagtgcc acgcctgatg agaagttact aaaggaaatc aagcagacat
    22501 ttgagctcca caaacttgcc ttgcgctttc atcggcgctt gcttcctgaa cccgtgcttg
    22561 ttttcatgaa taattggcga caaaaatgtg gaaacaaaaa gaaaatcaac tctttggtgc
    22621 ggatcattca gcaactaatc aaagaaaacc gtatcctttt attttgtcca agtattacga
    22681 tgatgcatcg tttaaaaatc acactgcaag aagcttttcc agaatatgag ataacagatg
    22741 tttcttcaca agacgatcaa cgggcaaaga aagttcagaa aatgcgagaa gcaatatacg
    22801 agatactgtt aaccacaatg atcctagaaa gaggagtcac atttgaaaga atctctgtca
    22861 tcgttttagg agcagatcat ccagttttta ctaaatcctc tttggtgcaa atcgcaggaa
    22921 gagctgatcg taaaggtcct tatacgaaca gtcgagtcta ttttttctat gaagaaaaaa
    22981 cttcagctat tcgaaaagcc tgtcaggaaa tcaaagaaat gaacgaagaa gggaagcaga
    23041 tgctgtgaga tgtagttgct gcggtaaaga catcattcaa aatttaacat tcagcgagat
    23101 catcggagtg tcgaaatcta gacttcctca gacatgttca gtttgccgcg cacaattcca
    23161 tttattagaa gcaaaaggtt gtgcaggttg tcaaaaacca atccatttga aatacgagga
    23221 gacgaaaaag aaagcaaata ctagtttcgt ttactgcaac gactgtcaag aatggaagaa
    23281 gaaatatcct gcatatgatt ttcaacaccg cgcctttttt acgtacgatg aaaagatgca
    23341 ggcttggatc aatcggtaca agtttatggg agatatccga ttagcaggga cttttgcata
    23401 taaatggact cagataaaaa aaagattacc cggcatatat ttattgtcca atacctttat
    23461 ctgaaaaaag gtggctagaa agaggattca atcaagtaag cgagatgttg aaagcagcaa
    23521 aaattccttt tcagatgctg ctcaaaagag agcaacatct gcttgctcaa gcaaaaaaca
    23581 cgcgaaagga aagattggag atgcctcagc cttttgagct tgccgtacct ctttctaaga
    23641 tacaacataa aaaa
//
LOCUS       DAZUJR010000045        23187 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.045, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000045 DAZUJR010000000
VERSION     DAZUJR010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23187)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23187)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23187
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.045"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            313..2784
                     /locus_tag="ACG804_001657"
     CDS             313..2784
                     /locus_tag="ACG804_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFS4832589.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(2887..4623)
                     /locus_tag="ACG804_001658"
     CDS             complement(2887..4623)
                     /locus_tag="ACG804_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFS4832590.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(4620..5324)
                     /locus_tag="ACG804_001659"
     CDS             complement(4620..5324)
                     /locus_tag="ACG804_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFS4832591.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            5455..5958
                     /locus_tag="ACG804_001660"
     CDS             5455..5958
                     /locus_tag="ACG804_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HFS4832592.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            5918..6256
                     /locus_tag="ACG804_001661"
     CDS             5918..6256
                     /locus_tag="ACG804_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HFS4832593.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            6277..7695
                     /gene="ffh"
                     /locus_tag="ACG804_001662"
     CDS             6277..7695
                     /gene="ffh"
                     /locus_tag="ACG804_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HFS4832594.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            7807..8385
                     /locus_tag="ACG804_001663"
     CDS             7807..8385
                     /locus_tag="ACG804_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HFS4832595.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            8389..8910
                     /locus_tag="ACG804_001664"
     CDS             8389..8910
                     /locus_tag="ACG804_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HFS4832596.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(8989..9543)
                     /locus_tag="ACG804_001665"
     CDS             complement(8989..9543)
                     /locus_tag="ACG804_001665"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HFS4832597.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            9796..10071
                     /gene="rpsP"
                     /locus_tag="ACG804_001666"
     CDS             9796..10071
                     /gene="rpsP"
                     /locus_tag="ACG804_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HFS4832598.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            10083..10334
                     /locus_tag="ACG804_001667"
     CDS             10083..10334
                     /locus_tag="ACG804_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HFS4832599.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            10459..11250
                     /locus_tag="ACG804_001668"
     CDS             10459..11250
                     /locus_tag="ACG804_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832600.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            11420..11941
                     /gene="rimM"
                     /locus_tag="ACG804_001669"
     CDS             11420..11941
                     /gene="rimM"
                     /locus_tag="ACG804_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HFS4832601.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            11931..12692
                     /gene="trmD"
                     /locus_tag="ACG804_001670"
     CDS             11931..12692
                     /gene="trmD"
                     /locus_tag="ACG804_001670"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HFS4832602.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            12828..13175
                     /gene="rplS"
                     /locus_tag="ACG804_001671"
     CDS             12828..13175
                     /gene="rplS"
                     /locus_tag="ACG804_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HFS4832603.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            13548..14210
                     /locus_tag="ACG804_001672"
     CDS             13548..14210
                     /locus_tag="ACG804_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832604.1"
                     /translation="MKQNDGRIIWKNQSELKLILTINEFIEKHGITSSRQYQKKLSEN
                     PNSAPSMWFINKKYGSWENLLISIGRENTGYGKWARMSEQELLEIVEAFIKCEKITSQ
                     RMYEQKSVGKNIPSLSTIKKMLGDIRPLFKEKNDGSRFTDFELLLELKNEIIRLKLQD
                     DLSMTKFRKLVQSPKLPSVDTIMKRTNKNWEELMAEIGFDYRRIKIYKQRNNLSKTKK
                     TK"
     gene            14289..17516
                     /gene="fss3"
                     /locus_tag="ACG804_001673"
     CDS             14289..17516
                     /gene="fss3"
                     /locus_tag="ACG804_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HFS4832605.1"
                     /translation="MKKPRFKNWRLLATLSLLCQTIGGSLGPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSEKAKLVSVLWKEAGTDVDTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     ESKINQAIADYQKKPSFHNSTVKTVLGQSTTVTDTNGLNLSEFDEVVENIANIDYRVN
                     GNQLVITPNANSKESGELTLKKSANTGTPVAYKMAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKETGNVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGAKVTIT
                     EKSVPAPYTIDTTPITATIKSGETISVTSKNTREKGQIILNKMGVETGTDLWNDKYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASNGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGNETQGKAEFKGAEYTL
                     FTAKDGQAVKWSEAFKPELVKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDNEKNAVITRDVTAKEQVIRFGFDFFKFAGSAAGTAETGF
                     NDLTFKVSPLEGTSEITGAEDEAITAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKADYTKSEYIFTITEKGQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLGTWKDGGKELTDLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     EATKAAQEKDEKAKPVVIAETTATLANKEKTGTWKILHKLTAEQVLDKTIVLFNYVYE
                     NKKPYEAGDDPVAKDASLNNQAQTVNCTVERHVSIQTKAHLEDGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDNTTKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYGKDGNINGKHNEDLKEKTQTLTPKKVPTTPSAPEQPEIPTVP
                     SDSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            17630..17944
                     /locus_tag="ACG804_001674"
     CDS             17630..17944
                     /locus_tag="ACG804_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFS4832606.1"
                     /translation="MELKFVVPDMAETFGKIRYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            17957..18331
                     /locus_tag="ACG804_001675"
     CDS             17957..18331
                     /locus_tag="ACG804_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFS4832607.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIMDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPDQGNSTNQNEGKK"
     gene            18341..18685
                     /locus_tag="ACG804_001676"
     CDS             18341..18685
                     /locus_tag="ACG804_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HFS4832608.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLTKALTYDEKMFLIMHQGLL
                     EVGNDVEEDFDVLNWLGEEESFFMVIEVNESLCREAETVLEEIGVEMPDAIEVFLKQL
                     VETKQLPIAVND"
     gene            18756..20108
                     /locus_tag="ACG804_001677"
     CDS             18756..20108
                     /locus_tag="ACG804_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HFS4832609.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQELRQFDI
                     SKLSLSTIEIVRSIKDLIYLLGSLVLSGSTMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTKETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDIIANRIGIDEVVAESGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFVLDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMTRSKAMKEMPNYKTGENYAFLGLPPNFLIFDEYVVYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVDKKFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREISDIGGLNVNTEG
                     "
     gene            20168..21310
                     /locus_tag="ACG804_001678"
     CDS             20168..21310
                     /locus_tag="ACG804_001678"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HFS4832610.1"
                     /translation="MTFLDLFAGIGGFCLGMEQAGHQCIGFCEIDDFARQSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     AAILQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQNRERI
                     FLIGHSRDACTEQVFPIIGSSPTSDQNIRNLLNINPSNRGMGGQVYGSDDVAPTLTGD
                     EGIKIALPVDDGISVAGMLLGNFEQGNRVYEITGTAPTLSTKQGGTKIMLRKNETEYQ
                     EVKPGNSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKEVKTDDL"
     gene            21335..21589
                     /locus_tag="ACG804_001679"
     CDS             21335..21589
                     /locus_tag="ACG804_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832611.1"
                     /translation="MIGKIQSDPELEEELYRLNFDIRKNGVKVPDDPYVIDEETDARM
                     ELNQVISELERIADFAKEPDIRQYLFEIKAELEIEGITAE"
     gene            21845..23029
                     /gene="mobT"
                     /locus_tag="ACG804_001680"
     CDS             21845..23029
                     /gene="mobT"
                     /locus_tag="ACG804_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobT family relaxase"
                     /protein_id="HFS4832612.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATTCGLSRPYLNQIENGGV
                     TASTKTMRKIFDQLESFNPELPLTLLFDYVRIRFPTTDARKIIQEILHLKFDYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKPDDKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNQKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVNNTRLSDRHKKILEQQSMAIENL
                     II"
     gene            23026..23163
                     /locus_tag="ACG804_001681"
     CDS             23026..23163
                     /locus_tag="ACG804_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HFS4832613.1"
                     /translation="MKRGIVMEIVKDILLVFGGSMLGVTVMCLMHASAAADRAMEKKG
                     K"
BASE COUNT         7702 a         4119 c         4987 g         6379 t
ORIGIN      
        1 tatctgttaa tccgagtaat tttctagtat gattatccat tgagagactc ctttggtagg
       61 atgacgtttt ggtcgactaa attttaccaa aagtgagtct ctttttgagt tgaaacgaag
      121 aaaaagtgtt agtagaaaat cgccttcgat tttccaccaa cacaaaatat tatagaaccc
      181 tttttttttg ctatatgaca ggaatgaaag gtgtttgcaa gcttaatgtg aggaacactt
      241 tccatatctg ttctatactg gataggagaa gtttggaaat atccagaaaa cgaaatcaat
      301 cgaggtagcc acatgaagaa taaatggata aatcgaagta aaaaaaagaa agtaacacaa
      361 agatcatcag ataaagtcat ccgtcttttt ccatcgtata aagaaggatt aacggcagat
      421 caagtcaagg aacgaataga aaaaggtgca gcaaataatt cagtcgatcc cacattcaaa
      481 acaaatcagc aaatcgtatt ggaaaacata tttacgtatt tcaatttgat ctttcttatc
      541 ttagccattt tgctttgttt agtagaatcc tataagaact tgactttttt accagttatc
      601 atagccaata caggaatcgc catttttcag gaaattcgat ccaaaaagat cttggacgaa
      661 ctaaatgttt taaatacagc aaaagtcaat gtcatacgag acgggataga acaaacaata
      721 gatatagaag accttgtaat agatgacatt gttattttag agactggata tcaaattcca
      781 gcagatgcag aggtcgtgga agggaaactg caagttaatg aggctttatt gacaggcgaa
      841 gcagatgaaa taaccaaaga aataggtgat ccattaatgt ccggcagttt cattgtttcc
      901 ggaaaagctt acgcccgatt agacaaagtt ggagcagatt cgtatatttc ccagctgaca
      961 gtcaaagcca agacaatggg agaaggagaa cagtcggaga tgattgcttc tcttaatcaa
     1021 ttgatcaaat ggattgggat catcattatt cctatcggta tcctgctttt ttctcaaagt
     1081 tactttttta atggaaacac gatcaaagaa agtgtcgttg caatggaagc agcattgatc
     1141 ggtatgatac ctgaaggact gtacttgctg acgacgattg cattagcatt aagtgcgact
     1201 aaactagcaa agcaaagagt tcttttacac aatatgaaaa gcattgagac attggcaagg
     1261 gtaaatgtcc tttgtgtaga taaaacagga acgatcacag aaaataaaat gtctgttcaa
     1321 aaaatgatcg tctctaaaaa acaagaaata atcagtcagt cagatcaatt ggaagcatgc
     1381 attgctgact atgcaaaagc gatggcagga gacaatgcaa caatggaagc tgttaaagca
     1441 tattttacaa aaaccactga tcaatcctat caccatgtta ttcctttttc ttctgtccaa
     1501 aaattcagca gtgtagcgtt ggcagacaag gtgtatgttt taggagcgcc cgaaatggtt
     1561 ttgcgcgatc aattgccgga atatgcggaa gagtttgttt ctttcgctga aaaaggctat
     1621 cgcgtgttgg tctttggtgt gtacgatggg attcttgaag aaccagtatt gacagaagca
     1681 gtcacaccat taggctatat tctgattgct aatcctatca gaaaagaagc aagagccaca
     1741 tttgattact tcaaaaaaca gcaagtagcc atcaaagtga tttctggaga taatccgctc
     1801 accgtatcca atgtagctgt ccaagcaggg atttcacatg ctgatcagta cgttgatgca
     1861 tctaaattat cagaagaaga atatgaagca gctgtcgaaa aatatacagt ttttggacgc
     1921 gtcaagccag aacaaaagaa aatcttcgtt caattgataa agcgtaacaa tacagtagct
     1981 atgacaggtg atggcgtgaa tgatattcta gccatgaaag aagcagactg cagtatagcg
     2041 atggcttccg gaaatgaagc cgccatgcag gcctcacaag tggtcttact tgattctgac
     2101 ttttcacgca tgccagaagt tgttgcagaa ggacggcgcg ttgtgaacaa tattgagcga
     2161 tcagccagct tgtttttagt gaagaatatt ttctcctttt tgctctcact gttttcagtg
     2221 atctttgctc tgacctatcc tttagaacca tcacaaatca cattgattag tttgtttact
     2281 atcggacttc catctttctt gcttgctcta gaagaaaaca aaaagcgaat cagagggaaa
     2341 ttcatcatga atgtgatgga aaaagctgtg ccaggtggac taacagatat gatcgtagtc
     2401 ggtgcgttgg tgatctgcgg ggtgactttg aatctaaata aaacagatgt ttctacagca
     2461 tctaccatgc ttttgattgc agtagggttc ctcgttctct ataaaatctg ttcaccgctg
     2521 aataaattca gaagtcagat cattcttttc tgtgctagcg gtaacttttt ttcggtcatc
     2581 tttttgcata agctgttttc aatcaccggt atctcagctg tatcactttt gctgttgagc
     2641 attctatttt tctcggcaga ttcgattttt aggcatttga ccacattggt agaatatttg
     2701 tttgaacgta aaaatgaaaa agagcaaaag ccgtttagtc gcgtagctaa aaaatttcta
     2761 tcgatattta aacgagaaaa ttgacgaaaa gtatctcaaa aaagagtaaa aaagaacaac
     2821 cactcgtgta tctttcgaag caggatgagt catccaactt taaaacgcac gagcagttgc
     2881 tcttttttac attttcggaa tggtaacggt gaaagtcgaa cctgttccaa gatgactgtc
     2941 tacagtaatc gtaccattaa ggagttgcac gtagtctttt acaatcgcta accctaatcc
     3001 ggtcccgcct gaatgtcggc ttcgcgcctt gtctacgcgg taaaaacgct caaagatccg
     3061 ttcctgatcc tcaatgtcga tacctatacc aaagtcttgg acagaaaacg atagatcatc
     3121 tgttgcctga tagcggataa taatctcgct gtcgcttttt gaatattgga cagcattttc
     3181 aattagattt ttgataattg gataaaggat atctgtttta gtagtaaatg gttcgttctt
     3241 tccaatcaat cgaatcgtca accgtttctt ttcgatgatt ggctgataat tttgaacgat
     3301 ttgctggaaa taaggttctg tataaattgt ctggatctcg taagaattct cgccatcttt
     3361 tgacagctgg atgatttccc gaatcagttt atctaaccgg atcgcatctt tttgcatgat
     3421 ctcaagaaaa gaagtcagag tttgcgggtc atcttttgca ccatccagta aagtctcggt
     3481 aaaaccaatc agtgaagtca caggagtttt taattcgtga gagacgttgc caacgaaatc
     3541 cttttgtagc ttttctaaac gtcgcacttt cgttaagtca tacgccaccc ctagaatctg
     3601 tccggtacct tctgaattag taaagtagcg caaactcaag tctaatgtct gccgaccttc
     3661 tgtaagggtg atctcctgat ggatcagcgg atgctcagga gtcacttgat gaatcagctg
     3721 aatgagtttt ggctcttgaa tgacttctgt gtaccgctgt tcaggttgat agcttaccac
     3781 gtttaaatgt agctgcatct ttggattaag cagtagtaaa cgagaatcag catcatcaat
     3841 caggaatacg ccaatcatca gttcgttcag taacgtatat aattgctctt ctgtggtagt
     3901 acacgcccga tacatcttac tcatttgttc gctcaacgca ttaatcgtct gatacaattc
     3961 ttcccattga tcgggtgttt gcatgattac ttccgcctga ttaggatttt gcaccatttt
     4021 ttttagtacg ggcagcacgg ttttcaatgg ctggtttttt tgatagatca gataatagat
     4081 cattcctgca agaacaagga agaaagacag aaagaagaaa aagacccaac ggcgaaaact
     4141 ctcagttctc ggtaaaaaac cgcttgtcgg ttctgcgata cgtaaaatgg cttctaactg
     4201 gccacttttt ttgactggta atgcgacata taaaagatcc tcattcaaag tagtactttt
     4261 gcgcaaagcg ctacctaggt tcccaccatt caatacggct ttgatttcgg gacgggagtt
     4321 tcgctgttca ttcaatgttt cattgtttgt gtcaaataag atctttccag tagcatccat
     4381 taaagtaatc cgttcgttcg actgatggac gaattcttcc aaagcagttt tgttttgcgc
     4441 tgcttggagg ttttcgacat ctaattgccg gatcagcagt tgtgcttttt ttgtcaggta
     4501 gctttcttgc tgttccacga tctgctgttg aaaataatgg gaaatcaatt gccagccacc
     4561 aaaaaacaaa ctaactaaaa gaataagaaa gaagagacgt tcataaattt ttttccattt
     4621 catcgtttgg gttcctgaaa cttatagcca aatcctctaa tagtcaccaa gtactttggg
     4681 tgttttggat ctcgctcgat tttttctcgc aaatgactaa cgtgtacatc tacgattcgg
     4741 ctttgtcctg cgaagtcaaa attccaaatg cggtctagca atgtgtctcg gtcgatcaca
     4801 cggtcttttc gtttcatgaa ataaacaagt aattcaaatt ctttcggtgt tagttcaatc
     4861 agatggtcgt ctacggtcac ttgataattg gtcaaatcag cagtgatttg tccaatcgat
     4921 agatattcag gctcagcttc atcttttgat tgcttacgag gttcaattcg tctgaatatt
     4981 gctttcatac gggctaatac ttcgcgagga ctaaatggtt tggtcaaata gtcgtcagca
     5041 cctatttcta ggccaatgat ccgatccact tggtcatctt tagccgtcag catcaaaatc
     5101 ggtgtttcat ttttttcttg acgcagccgc tgagtgatct ccatgccatc catcgttgga
     5161 agcatcacat ctaaaatgat gaaatcaaat gattgttcta atgctaattc taatccttcg
     5221 cctccatctg tggcactggt taccttgtag ccttcttttt ccaaattgaa cgtcaagagc
     5281 gttacaatag aaggttcatc atcaacaact agtatttttt tcattcaaat ctcctttaaa
     5341 taggtttcat tctgtttata ttttagcata gaatcagtac aaagggctat tttacaaaag
     5401 aaataaatgg tataatagga aggcactttg ctgaatagaa aggaagagca gtcaatgatt
     5461 ggaatcagtg catgtttagg cggtctggcc tgtcgctatg atggacagaa aaaagaagta
     5521 ccagaattga tggaactagt tgaaactgga gaagctgtca tggtctgtcc agaagtgatc
     5581 ggcggattac caattcctag agatcccgct gaaatcattg gtggaaatgg attcgatgtg
     5641 tggaaagatc aagcaaaagt atggacgaca agcggcgaag atgtaacgga agcgtacaaa
     5701 aatggcgcga tcaaagccta tcaaaaattg caggaaaaac acattgatct agtcatcatg
     5761 aaggaaaaaa gcccttcatg cggaacccat tcgatttatg acggaagttt ttccggaata
     5821 aaaaaaaatg gtgccggagt ggctactgct tattttattc agcaaaaaat gactgtgctc
     5881 tctgatgaag aatggctgaa aactagaggt gagcagaatg gaaatcgaaa agaccaatcg
     5941 aatgaacgcg ctctttgaat tttattcgac cttattgaca gaaaaacaaa tgaactacat
     6001 ggaattatat tatgcagatg atttttcatt aggtgagatc gcggaagaat acgaagtaag
     6061 ccgacaagca gtatatgaca atatcaagcg gacaagcaag atcttggagg attatgaaaa
     6121 aaaactccat cttttttcta attatattgt tcgagaacag gtattggaaa atatgactgc
     6181 atatattaca gataagtacc cggaagataa aaaactactt gaatatgtac agcaaattca
     6241 agcaatcgaa gaataaataa aaggaatgaa gaaaatatgg catttgaaag cttaactgaa
     6301 cgtctccagc aggcgatggg aaaaataaga aaaaaaggaa aagtatcaga agctgacgta
     6361 aaagaaatga tgcgggaaat ccgccttgcc ttactagaag ccgatgttaa cttgcaagta
     6421 gtcaaagatt ttactaagcg cgtacgcgaa cgtgcggtag gggcagaagt gctggaaagt
     6481 ttatcacctg cacaacaaat cgtaaaaatc gttgatgaag aattgacgat cacacttggt
     6541 tctgaaacag cagagttaaa taaatcacca aaaataccaa ctgttatcat gatggctggt
     6601 cttcaagggg caggtaaaac gacctttact ggtaaattag ccaattattt aaagaaaaat
     6661 gaaaatgctc gtccgctcct aatcgcaggg gacgtatatc gaccagctgc gatcgaccaa
     6721 ttgaaagtat taggtcaaca gctagacgtt cctgtatttg atatgggaac tgaagtcagc
     6781 ccggtagaga tcgtccgtca agggatggag ttagcaaaag aaaagaaaaa cgactatgta
     6841 ttgatcgata cggcaggacg tctgcatatc gatgaaacat tgatggatga gttgaaacaa
     6901 atcaaagaat tgacgcaacc aaatgagatt ttgcttgttg tcgatgccat gactggtcaa
     6961 gatgccgtca acgtagctga tagcttcaac cagcaattag gtattacagg ggtcgtcatc
     7021 actaaacttg atggggatac tcgaggcggg gcagcactat cgatccgctc agtgacaggc
     7081 gcaccaatca aattcatcgg ttctggtgaa aaattgactg acttagaagt attccaccca
     7141 gatcgtatgg ctagccgtat ccttggtatg ggggatatgc tgacattgat tgaaaaagcg
     7201 cagcaagact acgacgagaa aaaagcggaa gaacttgcac agaaaatgcg ggaaaattca
     7261 ttcgatttca atgactttat tgaacagctt gatcaagtga tgggtatggg cccactggaa
     7321 gatctaatca aaatgatccc aggaatgaat caagtccctg gaatcgaaaa cgtcaaggta
     7381 gatccaaaag atgttgaacg caaaaaagcg atggtttatt ctatgacgcc agcagaaaga
     7441 gcaaatcctg atctgttgaa cccaagccgt cgtcgccgaa ttgctgccgg ttctggaaac
     7501 agtgttgttg aagtgaatcg aatgatcaaa caattcaagg aatcaagaaa aatgatgcag
     7561 caaatgtcca aaggggatat gaacatccca ggtatggacc aaatgtttgg ttcaggcgtc
     7621 aaaggaaaac taggcaaaat ggcgatgaat cgaatgatca agaaaaataa gaagaaaaag
     7681 aaaaaacgga aataagatga aaaaaacagc ttcggtacag actgaaaatg tctactgccg
     7741 gagcttttct atcagcaatt tttattcttt actaatacaa ttactctaaa cgaagaggtg
     7801 gcacagatga gatgtccgtg gagtgaacaa acagaaagta tgcggcaata tcatgatact
     7861 gtctggggtg ttcctgaata tgatgaccaa aagctgttcc gaaaattgat gcttgatatt
     7921 aatcaagccg gattgagctg gcagacgatt ttaaataaaa gtgaagcatt cgatgaagca
     7981 tatgatcgat tcgatatcaa aaaagtcgca aattatggag aaacaaaaat cagtgaacta
     8041 atggaaaaca aaggaattat tcgtaaccga agaaaaatcg aagcagccgt ccaaaacgcc
     8101 aaagcagtct tgaaaattca agaagaaatc ggcagttttt cagagtatct ttggtcgttt
     8161 tctaatggaa aaatcgttga ttcttcttat cattcacaag aagaagtccc aacaacaagt
     8221 cctctttcag atgaattagc aaaagatcta aagaaaagag gatttaaatt tatcggaagc
     8281 acaacaatct atgctttttt agaagctgtc gggatcatca atgatcacct tgacagttgt
     8341 ttccgcaaag aagaggtcgt acgtatcggc agaaagggcg aataaagcat gcgaaaaatc
     8401 atattttatg gtgctataag tttagatggc tatttggcaa cgaaaacgga tgatcttcaa
     8461 tggctttttg acactccaac aggtaagcaa actacttatg aagcttttta tgaaacaatc
     8521 gatacgacca tcatgggcag aaaaacttat caggaagcaa aaaaatattt ggagaccgaa
     8581 gcaatttatc cagagaaaaa gaatttcgtt ttttccaccc acgcacaatt acaattgcca
     8641 gatgctgagg tcgtaaacga agatcctgtt gcttttctaa aaaatctaca aatgacagaa
     8701 ggaaaagata tctgggttgt gggtggcggt cgattgatca aaccgctatt ggaacatcaa
     8761 atgattgatg aatggtatat ccagattacc cctgtattat taggggacgg gattccttta
     8821 ttccaaaaag gaacatatga agcgcgtttt gaaatgctag acacgacacg attcggtgaa
     8881 tttatcgaat tgcattatgt acgaaagtag aagtaaataa aataaaaaag gcaactatat
     8941 gcagaaatgt cctgtacata gttgcctttt ttattaccgt tatgcttttt actctgttaa
     9001 tttgttagaa aaatctagat acgcatctaa aatcgtttgg aagaaactta atgttccttc
     9061 aacgatatta ccattttcat caattagatt cgcaacgttt ccgatatatg cttccggttg
     9121 ctgcaaggtt ggcacattca aaaagacaag tgattggcgt agatggtggt ttgcgccaaa
     9181 gccgccgatc ccacctggtg atgcagtaac gactaaacct ggtttatgat cccaaacact
     9241 gtgtccataa ggtcttgagc ctacatctaa agcatttttc aatactgctg gcacagaacg
     9301 gttgtattca ggagtaacga aaacgacacc gtctagtccc ctcacttcct cacgaaaacg
     9361 agtccattca gcaggagcct gttctggagt ttcgagatcc tcattgtaaa atggcagatc
     9421 atcgattttt acaaatacac tttcgtaccc ttcaggaagc aatttcgcaa aagcttctgc
     9481 tacttttttg ttgtaagaat cttttcttaa actaccaata aaaaatccaa ttttttttgt
     9541 catacgattt ttcctccttc aaactatcta taataatctt acaaaagata agtaactgga
     9601 gcaaataaaa acacttactg acaaaagcta catagaagat agattactta tttttaacaa
     9661 aaaagaagtc taaaatcttc tattttctaa aaaaaatcga atttaatcaa gctgtaaaga
     9721 aaaaaagctt tacagggtaa aaaaaaactg ttacactaca tcttgtgaat aaaacaatgg
     9781 aggtggaaat aaataatggc agttaaaatc cgtttaaaac gtatgggttc taaaaagagt
     9841 ccgttttacc gtatcgtcgt agctgattca cgttctcctc gtgatggacg tttcatcgaa
     9901 actgtaggta cttacaatcc tttgaaagac cctgcagaag tagttttaaa agaagactta
     9961 gttcttgact ggttatcaaa aggtgcacaa ccttctgaca ctgtacgtaa catcctttca
    10021 aaagaaggcg ttatgcaaaa acaccacgaa gctaaattct caaagaaata aggtgaccgg
    10081 atatgaaaga tttaagcgac ttagtcttaa caatcgttcg tccgctagtc acttatcctg
    10141 atcaagtcaa gttagacgtc gtagagtcga aagactttta cgagtacaat ctaacagtgg
    10201 ctcctgaaga tattggccgt atcattggaa aacaagggcg tgttgctaaa gcaatccgca
    10261 caatcgttta cggtgttcgg atcaatgcac cgaaaaaagt gcgtttgaat atcatcgatg
    10321 ataaggaaaa gtaaataaac gtgctgtact cgaattttcg agtgcagctt ttttgttttt
    10381 tttattaatt gaagaaatga ttatttggca aaacaagcaa gaaagcgtat ccttatagga
    10441 ggagggagtg aacagccaat gagaaagaaa atgttattta ttccatttgc tctattgtta
    10501 agcgcttgta gttcggttac tcaagaatca gacaatacac atctatcaag cagtatatct
    10561 gaaactgtta ccagtccaga aaaaagtagt accaaaacgg cttccaccac tgaacaaaca
    10621 atggctacct caaataatga gaaaaagact gctttagacc agttgaaaga acaacagcca
    10681 aatgttccca tgcctctaga tgtaccagtc tcttcaggct atctcaatat cgcagcgaca
    10741 catacaaagc aaggttattc tattttatat tacagaacag atcgtcccct cgggttgaat
    10801 gctgacgaat tgaatcaaga aacgcctatt gcaacctatc tatatcaata tgggtttgct
    10861 tctagtcaag aaacaatcca agttttgcag ccatttgaga tcgacacaaa tggtcagcaa
    10921 gtggacttag gttctcgaat cacagggtat cagcaaggtg cagcaggttc aagttttctt
    10981 gaatggcaag aaggaaactg gcgtattcga atccgtggga ataatataga aggccaagat
    11041 cccttactat tagctaaaga aatcgtagct tatttggaag aaaacagtct accagcacct
    11101 gaacaatttg gtaaaattac tgttgatatg ggtgatacga cgaatcgagc cgtagaagta
    11161 agctggcaag aaccgaaaaa tgcctatacg atcactcatc aagatcctat gtctgcgttg
    11221 aagatggcag tttctatgaa gaggttgtga aatcagcgcg ctgatctgag cccatcattt
    11281 aactccaagt cacaggaagt aatcaaaaat agcacgccgc atttttgcat aattttggct
    11341 taatacctta aaagaaaact agaattgcct cttcacacat gctaaaataa aacagacaaa
    11401 aaagaaatgg ggatataagt tgactgaata cttgaatgta ggaaaaatcg taaacacaca
    11461 aggtatcaaa ggcgaagtcc gtgttatctc aacaacggat ttcccagaag aacgttacaa
    11521 aaaaggaacg gtgctaacac tattccaaga cggaaaagca cctgtggaat taacagtcaa
    11581 aagtcatcgc aaacataaaa attttgactt attgagtttt gaaggacatc cttctatcaa
    11641 tgatgtggaa aaatatcggg atggcatatt aaaagtgtca aaagacaact ctgtagatct
    11701 agctgaaaat gaattctatt accatgagat catcggtctg catgtattag aagatggaac
    11761 tgagttaggt aaagtaaaag aaatcttgtc accaggtgcc aatgatgttt gggtcgttca
    11821 acgtccgaaa aaagctgata tattgcttcc atatatcgct tctgtcgtca aagaagtcga
    11881 tttagaagct ggagtggtcc gtgtagaaat tccagaagga ctgattgacg atgaagattg
    11941 atgtattgac tttatttcca agaatgtttg aaggtcctat gggggaatcc atcatcggta
    12001 aggctgtaga taaaggatta ttagatatca atatctctaa cttccgcgat tattcagata
    12061 acaaacatca gacagtagat gattatccat acggcggtgg agcaggtatg ctgctcaaag
    12121 tccagcccat ctatgataac atccaagcca ttgaaaaagc tgcaccggat gtcaaaaaaa
    12181 gagtaattct tcttgaccca gctggtaaac gattcgatca gaaaatggca gaagaatttt
    12241 cacaagaaga acacttagta ttcatttgtg gtcattatga gggatatgat gaacgtatcc
    12301 gcacattagt gacagatgaa gtttccttag gagattatgt ccttactggg ggagaattag
    12361 gtgcgatggt catgatcgat gcaacagttc ggcttttgcc agatgtgtta gggaatcaga
    12421 cttcagctca aacggattct tattcaaccg gtttattgga acatccccaa tatactcgcc
    12481 cggcagaata taaagggatg aaagtaccag aagtattgac aaatggaaat cataaattga
    12541 ttgaagaatg gcaattaaaa gaatcactaa gaaggaccta tcaacgtcgg cctgatcttt
    12601 tggaaacact tgaatggaca cctcaaatga cgaaattttt agaagaaatc aagaaagaag
    12661 aacaagaaaa aacagcagat gaagccaagt gactttttct aaaatcttct ttacagtagg
    12721 ttgataatat gttagtattt tatggtgagt gcaaaagcac ttaactatta cgatattccg
    12781 ctgtgagaaa agctcataag aatatttgga ataaggagaa gaaaaccatg aatccattaa
    12841 tcgaagaatt aacaaaagaa caattacgtt ctgacatccc agcgttccgc cctggtgaca
    12901 ctgtgcgtgt tcacgcaaaa gttgttgaag gtactcgtga acgtatccag ttatttgaag
    12961 gtgttgttat caaacgccgc ggtgctggaa tcagcgaaac ttatacagta cgtaaagttt
    13021 ctaacggagt gggcgttgaa cgtacattcc cattgcatac accacgtgtt gcaaaaatcg
    13081 aagtagttcg ctacggtaaa gtacgtcgtg caaaattgta ctacctacgt gcattacacg
    13141 gaaaagctgc tcgtatcaaa gaaatcagaa gataaacacg gaaaacttcc ttggaaatct
    13201 gaaatttgtg aaaagtcctt gtatatcaag ggctttttct tttttctcta tcacagtttt
    13261 aagccatttt tggctgtttt ggaccatttt tcaatcatat tcccttaaaa attgtcctag
    13321 attgtccgac attgactatc agtgtcgtca aaatagggca aaatttagta gtcagcttga
    13381 cgacaaatat aatacgaaaa ataccaaaac atttaccgaa tttagcaact tttgaaccca
    13441 agtttctcaa agggtcagct attagcaaaa aagacaaaac atgtactttt ctactaaaaa
    13501 gttgatgtga taggcttcta tctaaataac tattaggagt ttttatcgtg aagcaaaatg
    13561 atggacgtat catttggaaa aatcaaagtg agttaaaact gattttaaca attaatgaat
    13621 tcatcgaaaa acacggaatt acatctagcc gtcaatacca gaaaaagcta tcagaaaatc
    13681 caaattctgc accaagtatg tggttcatta acaaaaaata tggatcatgg gagaatttat
    13741 tgattagtat aggacgagaa aatactgggt atggaaaatg ggctagaatg tcagaacaag
    13801 aattattgga aatagtagaa gcctttatta agtgcgagaa gataacctct caacgaatgt
    13861 acgaacaaaa atcagtaggg aagaatattc cttcacttag taccattaaa aagatgttag
    13921 gagatatacg tccacttttt aaagaaaaaa atgatggatc tcgatttact gatttcgaac
    13981 tgctgttaga actaaaaaat gaaataatcc gattaaaact acaggatgat ttatcaatga
    14041 caaagtttcg aaaactagtt caatccccaa aactaccatc agttgataca attatgaaaa
    14101 gaacgaacaa aaattgggag gaattgatgg cagagattgg atttgattat cgaagaatca
    14161 aaatttataa gcagagaaac aacctatcca agacaaagaa aactaaatag tatcactcta
    14221 aatcagacgt tcaaaattaa aatttggacg tcttttttat tacccaaaaa cgaaaggaga
    14281 tttattttat gaaaaagcca agatttaaga attggcgttt gctcgcaaca ctgagtctat
    14341 tatgccaaac aattggtgga tcgcttggcc caacgattgc ctttgctgat gaaattactc
    14401 atccacaaac ggtaactgtg gaattggatt tggctcacca gtatgctgtc gaaggtacat
    14461 ttagcgatgg tcgtcccatg tcagaagtta ccgttccgca ctatgcagtt tacaatggtg
    14521 tgaagcaaga tattttctgt attgagccag gggtgccgat ttacaatgag ttcactcctg
    14581 gttatgagaa aaatccattg cctgatatgt cggagaaagc gaaattagtt tccgttttat
    14641 ggaaggaagc tggtacggat gtggatacac atattgtggc ccagaagatg atttggcaag
    14701 aagttaatgg ctacacgctt cactcaatta aacgttctga tggtagtgca gtaaatatcg
    14761 cagccattga gtcaaaaatc aatcaagcca ttgcggatta tcaaaagaaa ccaagcttcc
    14821 ataactccac agtgaaaacc gtgttaggtc aatcgactac tgtgacagat acgaacggct
    14881 tgaatttatc ggagtttgat gaagttgtcg agaatatcgc aaatattgat tatcgtgtga
    14941 acggcaatca actagtgatt actccaaatg ccaattcaaa agagagtggt gaattaaccc
    15001 taaagaagtc agctaataca ggaacaccgg tagcttataa aatggctggt caacaaactt
    15061 tgatggcggg ggcaattgat aagcccaata cctacacaat caaaattgat gtggaaactg
    15121 agggttcttt gaagattaaa aaagtcgata aagaaacagg aaatgttgta ccgggaaccg
    15181 ttttccattt agactttgga aaaacattac ctgcaaaaga cgtgaccacc gataaagaag
    15241 gcattgcgac attggatgag attcctcatg gcgcgaaagt aaccattact gaaaaatcag
    15301 tgccagctcc ttatacgatt gacactacac caatcaccgc aaccattaaa tctggtgaga
    15361 ctatttctgt gacttcaaaa aatactcgcg aaaaaggtca aatcattttg aataaaatgg
    15421 gggtggaaac aggaactgat ctttggaacg acaaatactc attagccgga aatacgtttg
    15481 ccattcgcaa agacagtcca accggtgaaa ttgtccaaga aatgaccacg gatgaaaaag
    15541 gtcatgcgga aacaccaaaa gagattgcca atgcgttgga attgggaacc tattatgtga
    15601 ccgaaaccaa agctagtaat ggctttgtga atacctttaa accagtaaaa gtcgaattga
    15661 actatgtcaa tcaaaccgtg gctcttgtta ccagtaacgt aaaagggcaa aaccaagaaa
    15721 tcactggtga aaccactttg acaaaagaag acaaagatac cggtaatgaa actcaaggta
    15781 aagctgagtt taaaggagct gaatatactc tctttactgc aaaagatggt caagcggtca
    15841 aatggagtga ggcttttaaa ccagagttag tgaagggaac gaaagcttct gatgaaacgg
    15901 tgactttgac tttagatgaa aagaatcaag ttgctgttaa acacttagcg attaatgagt
    15961 attactggca agaaaccaaa gcacctgaag gatatacctt ggatgaaaca aagtaccctg
    16021 tttccatcaa aaaggtggat gataacgaaa aaaatgccgt gattacccga gatgttacgg
    16081 caaaagaaca agtcattcgc tttggctttg atttctttaa atttgctgga tcagctgctg
    16141 ggactgccga aactggcttc aatgatctga cctttaaagt atcgccattg gaaggaacca
    16201 gtgagattac aggtgccgaa gatgaagcaa ttacagctta taacgagcaa ctaggttttg
    16261 atggctatgg caagtttgaa aatcttcctt atggggatta tttacttgaa gaagtagagg
    16321 ctccagaagg atttcaaaaa attacgccat tagaaatccg ttctactttt aaagaaaata
    16381 aagcggatta cactaagagt gaatacattt ttacgattac cgaaaaagga caaaaacaac
    16441 caattaaaac ggtgaccgtt ccttacgaga aactgacgaa taaagcattt tctgttagct
    16501 tgaatcgttt gatgctctat gatttacctg aagaagaaga tagcttaact tctcttggga
    16561 cttggaaaga cggaggcaaa gaattgacag accttgattc taccgagcta gttgataaat
    16621 tgagctataa cttgcatgaa atcaaagaag actggtatgt ggtagcgcaa gccattgatg
    16681 tggaagcgac aaaagctgcc caagaaaaag atgaaaaagc caaaccagtg gtaattgccg
    16741 aaacaaccgc aacgttggcg aataaagaga aaacaggaac ttggaaaatt ttgcataaat
    16801 taaccgcaga acaagttttg gataaaacca tcgtcttatt caactatgtg tatgaaaaca
    16861 agaaacccta tgaagcaggt gatgatccag tagcgaaaga tgctagcttg aacaatcaag
    16921 cccaaactgt caattgtacg gtggaacgcc atgtttccat ccaaacaaaa gcccacctag
    16981 aagatggttc gcaaaccttt actcatgggg atgtggtgga tatgttcgat gatgtgtcga
    17041 ttacccatga tgtactggat ggctcaaaag aagcttttga aacaattctg tatgcattac
    17101 ttccggataa tacgaccaaa gaaatttgga aatctggcaa aattgattat gaagtgaatg
    17161 acaaagaatt cactaaaacc gtacttgcgg aaaaagtgga cacaagtaaa tatccagaag
    17221 gtacaagttt taccttcaaa gaaattaact atggcaaaga cggaaacatc aatgggaaac
    17281 acaatgagga tctaaaagaa aaaactcaaa ctttaacacc taaaaaagtt ccgacaacac
    17341 caagtgcacc agaacaaccg gaaataccaa ctgttccaag tgactctcaa gaatctagtc
    17401 ctacagtaaa gacattccca caaacagggg agaaaaattc taatgttctg ctgtttattg
    17461 ggtttacctt gatctttgcg actgctgggt attatttctg gaatcgccga aactaaggtg
    17521 atgtgatgaa acaactaaat aggaaaaacc aacgtgcgcg accgcctcct aaaaaaagtg
    17581 gtcgcgctat ttttgtatcc aaaactaaaa atgaaaagag gaaaagaaga tggaattgaa
    17641 atttgttgtg ccagatatgg ccgaaacctt tggaaagata aggtatgccg gcgaaggcga
    17701 agttttaact gaaggatatg ggcggaatac tacagtaatt ggtcgtagtt atcatttgta
    17761 ttccagtaag caacgagccg atgatattga agtggtggta gctgcggaag ccggcgaaaa
    17821 ggattttgac caagatcaac cactaaaagc cgtgaatccc catttggttg ccaaaggcta
    17881 tgagattgag aatcgtgggt ttaccgacta cgtgttgtat gtcgatgatt tagtgaaagc
    17941 ataggaggaa aagaagatga gattaacaga aggtattgtt gtagattcag gactaacgtt
    18001 tgggaaatta cgattttccg cattacgccg agaagtacgg aagcaaaatg aggatggaac
    18061 ggttagtaac gaggtaaaag aacggactta taatttgaaa tcctctgcgc aaggtcgaat
    18121 gatccaagtt agtatcccag caaatgtacc cttacgcgag tttgcctatg acgcagaggt
    18181 agagttggtc aatccaatca tggatacggt cgccaattat gttttccgag aaggaactac
    18241 tgtcaattgg ttcattaagg ccgatgattt agtcttgaaa cgacaaccag atcagggaaa
    18301 ttctacaaac caaaatgaag gaaagaaata ggtgaagcgt atggaaatta atgttgaaca
    18361 tattttagat tgtctcgatc aatatggaaa aggtgagcta acggaggaac aactcactaa
    18421 agcattaacc tatgatgaaa aaatgtttct gattatgcat caagggttac tggaagtagg
    18481 taacgatgtc gaagaagatt ttgatgtact gaattggtta ggggaagaag agtccttctt
    18541 tatggttatc gaagtaaatg aaagtctatg tcgagaagcc gaaaccgtat tggaagaaat
    18601 tggtgtggaa atgccggatg ccattgaagt ttttttaaag caactagtgg aaacgaaaca
    18661 actccctata gcagtaaatg actagcataa ctgcttgaaa ttggatcaat gaaatcctat
    18721 gaagcttttt tcgattggag gtggaaacca taaaaatgta caaagggcat cgtatacggg
    18781 caggagatca gcacttggtt tatcactttg ttcttggctg gctactcgct ctgttcatcg
    18841 gttggatgag cgtcttttat tttcaagagc ttagacaatt tgatatttct aagctatcac
    18901 tttctactat agaaatcgtt cgttctataa aagatttaat ctatttgcta ggaagtctcg
    18961 ttctttcagg aagcacgatg ttgctttata tacacttttt tcaggatcat tggcgcagtt
    19021 tgtggcatcg acaaaagcta gcccggatga ttctagaaaa tcattggtac gaagtaaaac
    19081 aaactcagag tgaaggattt ttcaaagacc tcaatagtag tcgaaccaaa gagacaatca
    19141 gttacttccc caaaatctat taccgtatga aggatggttt actttctatt cgcgttcaaa
    19201 tttcactggg aaaatatcaa gatcagcttt taaagctgga aaagaagtta gaaagtggtc
    19261 tatattgtga actagtagaa aaggaactca aagactccta tgtggagtac actttactgt
    19321 atgatataat tgccaatcga attgggatag acgaagtagt ggcagaaagt ggggctttgc
    19381 gattgatgaa aaatcaagta tgggcttatg attctttacc tcatatgtta atcgctggcg
    19441 gcacaggtgg tgggaagact tactttttac tcactatcat cgaggcttta ttaaaatctg
    19501 atgccgagct ttttgttctt gatcccaaaa atgcggactt agccgattta ggtacggtaa
    19561 tgcctcatgt ctattcccaa aaggaggaaa tttctgcttg tgtggaagat ttctatgagc
    19621 gcatgatgac tcgtagcaag gcaatgaaag aaatgcccaa ctacaaaaca ggagagaatt
    19681 atgcgtttct tggacttcca ccaaactttt taatctttga tgaatacgtg gtttatatgg
    19741 aaatgttaac gacgaaggaa agtgcggtga ttttgaataa gctcaaacaa atcgtgatgt
    19801 taggtcgtca atctggtttc tttctgattc tagcttgtca aagaccggat gcgaaatatt
    19861 taggagacgg gattcgcgat caatttaatt tccgggtggc tttgggtcgt atgagtgaac
    19921 tgggatattc catgatgttt ggcgaggttg ataaaaaatt ctttatgaag cgtatcaaag
    19981 gtcgaggcta tgtagatacg ggagggagtg tgattagtga gttttatacg ccacttgtac
    20041 caaaaggata tgatttctta agggaaatta gcgacattgg tggattaaac gttaatacgg
    20101 aaggataaaa taatagtatg tagcctagga gtgtcaagaa tcctgggctt tttttacgag
    20161 gtgatttatg acatttttag atttattcgc tgggattggt ggcttttgct taggtatgga
    20221 acaagcgggt caccagtgta tcggcttttg tgaaattgat gattttgctc gccagagtta
    20281 taaggcaatc catgatacaa gtaaggaggt ggaaatgcat gacatcacaa gtgtatcaga
    20341 cgagtttatt caatctctcg gaccagtgga tatcctttgc ggtggatttc cgtgccaagc
    20401 tttttcaatt gcgggaaagc ggcaaggatt ttccgatact cgaggtactt tattctttga
    20461 aatcgctcgg ttcgccgcta ttctccaacc taagttttta ttccttgaga acgtccgggg
    20521 attactcaat cacgaaggag gggctacgtt cgagacgatc ctccgaacgc tggatggatt
    20581 ggggtatgat gtggaatggc aagtgcttaa ctcaaaggcc tacgttcccc aaaaccgtga
    20641 gcggatcttc cttatcggac attctcgaga cgcatgtacc gaacaagtat ttcctatcat
    20701 tggatcgtct ccaacatctg atcaaaacat cagaaactta ttaaatatca acccttccaa
    20761 tcgaggaatg gggggacaag tctatgggtc agatgacgta gcgcctacct tgaccggtga
    20821 tgaaggaatc aaaatcgcat tgccggtaga tgatggaatt tctgtagcgg gtatgttact
    20881 gggaaatttt gaacaaggca atcgggttta tgagataact ggaacagcgc ctactttgtc
    20941 aacgaaacaa ggcggaacga agatcatgct tcggaaaaac gaaacagaat atcaagaggt
    21001 gaagccaggg aacagtgtga acctggcttt tcctaattcc acaagtcgtc gaggccgtct
    21061 gggaaaacaa agtgtgcata ccttattaac aggagaccaa caagcagtcg tcacggatca
    21121 gtatcaaatt cgaaagttaa cacctaggga gtgctggcgg cttcagggct ttccggactg
    21181 ggcttttgat cgagcttctc aagtcaattc agatagtcag ttgtataagc aggctggaaa
    21241 ttctgtaaca gttccggtca tttttgatat tgctagaaga ttaaaggagg taaaaacaga
    21301 tgatttatga tgagttgatt ggggaatcta ctgggtgatt ggcaagattc agtcagatcc
    21361 ggaattggaa gaagaactgt accggctcaa ttttgatatt cgcaaaaacg gggtgaaagt
    21421 ccctgatgat ccgtatgtaa ttgatgagga aacggatgct cgaatggagc tgaatcaagt
    21481 catcagtgaa ttggaacgaa ttgcggactt tgctaaagaa cctgatatcc gccaatactt
    21541 gtttgagata aaagcagagt tggaaattga gggtattacc gcggagtaac ggccaaataa
    21601 accactgata ggcactgacc gcgggggatt tgcgaagcag aaatcctccg tggtgctgtg
    21661 cctgtttatg gacggcgtta gccggccatg atgtctcacc ccccgtatct aacagggggg
    21721 tacaaaaaca caaaaaataa gcaagcaacg ataaggaatg gctgtcctat caaggataat
    21781 aagcaatttg tgtagatgtt aactgatttg aaaaagttaa caccttaaat ttggaggtga
    21841 gaacttggca caaaggaatt tagattatcg gctattaaaa gaccggcgta atgaatatgg
    21901 cgtttcacaa aataaattag ctacgacttg tggacttagt cgcccgtact taaatcagat
    21961 agaaaatggt ggcgtaaccg catcgacaaa aaccatgagg aaaatttttg accaactgga
    22021 aagtttcaat cccgagttac ctttaacgtt actgtttgac tatgtaagga ttcgctttcc
    22081 cacaacggat gcgaggaaaa tcattcaaga gattctccat ttgaaatttg attatatgct
    22141 ccacgaagat tacgcctttt actcctatca agaacaatat gttatgggag atattgtggt
    22201 gatgttgtca catgaagaag ataaaggcgt ccttttagaa ttaaagggtc gtggttgtcg
    22261 gcagtttgaa acttttttac tcgcccaaaa gcgtagctgg tatgactttt tcgaagattg
    22321 tctaaaagcc ggtggcgtga tgaaacgctt agacctggca atcaatgatc gagttggcct
    22381 gttagatatt cctgatttaa cgaaaaaatg tcagaaggaa gaatgtatct ccttgtttcg
    22441 taccttcaaa agctatcgtt ccggggaact gttgaaacct gatgataaag atggtatggg
    22501 caatactttg tatattggca gtcttaagag tgaggtctat ttctgtttgt acgaaaaaga
    22561 ctatgagcaa tatatcaagt tagggattcc tttagaccag accgaaacga aaaatcgttt
    22621 tgaaatccga ctgaaaaatg atcgagctta tcatgcaatt caagatttgt taaaaggtcg
    22681 cagtattgaa agtaccacat tttccattat taaccggtac ttgcgatttg cggataaggt
    22741 ggaaggcaaa aggcgaacta actggccctt gaatgaacaa tgggggcgct tcattggacg
    22801 gaatcagaag gaaattcaat taacttctga accgaagcct tataccattg aacgaacgtt
    22861 gaactggctt ggacgacaag tcgcccctac gtggaagatg gccaaggagt tggatcggtt
    22921 gaatcagaca acgtacattc aggatatggt aaataatact cgactatcag accggcacaa
    22981 aaagattttg gagcaacaaa gtatggcaat tgaaaatttg attatatgaa aagaggaatc
    23041 gtgatggaaa ttgtgaaaga tattttattg gtgtttggtg gcagtatgct tggtgttact
    23101 gtgatgtgct tgatgcatgc aagtgcagcg gcggaccgag caatggaaaa gaaaggaaag
    23161 tgatgaaatg aatttcggtc aaaattt
//
LOCUS       DAZUJR010000046        22862 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.046, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000046 DAZUJR010000000
VERSION     DAZUJR010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22862
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.046"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            3..371
                     /locus_tag="ACG804_001682"
     CDS             3..371
                     /locus_tag="ACG804_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HFS4832614.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            551..1492
                     /locus_tag="ACG804_001683"
     CDS             551..1492
                     /locus_tag="ACG804_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HFS4832615.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            1561..2292
                     /locus_tag="ACG804_001684"
     CDS             1561..2292
                     /locus_tag="ACG804_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFS4832616.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            2436..4616
                     /locus_tag="ACG804_001685"
     CDS             2436..4616
                     /locus_tag="ACG804_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HFS4832617.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            4636..5118
                     /locus_tag="ACG804_001686"
     CDS             4636..5118
                     /locus_tag="ACG804_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HFS4832618.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            5134..5895
                     /locus_tag="ACG804_001687"
     CDS             5134..5895
                     /locus_tag="ACG804_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HFS4832619.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            6026..7360
                     /gene="murC"
                     /locus_tag="ACG804_001688"
     CDS             6026..7360
                     /gene="murC"
                     /locus_tag="ACG804_001688"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HFS4832620.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            7667..8152
                     /locus_tag="ACG804_001689"
     CDS             7667..8152
                     /locus_tag="ACG804_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MaoC/PaaZ C-terminal domain-containing protein"
                     /protein_id="HFS4832621.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            8145..8828
                     /locus_tag="ACG804_001690"
     CDS             8145..8828
                     /locus_tag="ACG804_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HFS4832622.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGIILAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            8954..11599
                     /gene="polA"
                     /locus_tag="ACG804_001691"
     CDS             8954..11599
                     /gene="polA"
                     /locus_tag="ACG804_001691"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HFS4832623.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            11644..12480
                     /gene="mutM"
                     /locus_tag="ACG804_001692"
     CDS             11644..12480
                     /gene="mutM"
                     /locus_tag="ACG804_001692"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HFS4832624.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            12444..13073
                     /gene="coaE"
                     /locus_tag="ACG804_001693"
     CDS             12444..13073
                     /gene="coaE"
                     /locus_tag="ACG804_001693"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HFS4832625.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEILVGQIENWLFANRFL"
     gene            13125..13457
                     /locus_tag="ACG804_001694"
     CDS             13125..13457
                     /locus_tag="ACG804_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HFS4832626.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            13769..14260
                     /gene="nrdR"
                     /locus_tag="ACG804_001695"
     CDS             13769..14260
                     /gene="nrdR"
                     /locus_tag="ACG804_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HFS4832627.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            14283..15656
                     /locus_tag="ACG804_001696"
     CDS             14283..15656
                     /locus_tag="ACG804_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFS4832628.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            15656..16582
                     /gene="dnaI"
                     /locus_tag="ACG804_001697"
     CDS             15656..16582
                     /gene="dnaI"
                     /locus_tag="ACG804_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HFS4832629.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            16711..17151
                     /locus_tag="ACG804_001698"
     CDS             16711..17151
                     /locus_tag="ACG804_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFS4832630.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            17295..17996
                     /locus_tag="ACG804_001699"
     CDS             17295..17996
                     /locus_tag="ACG804_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HFS4832631.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            17993..19114
                     /locus_tag="ACG804_001700"
     CDS             17993..19114
                     /locus_tag="ACG804_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HFS4832632.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            19129..20361
                     /gene="pepT"
                     /locus_tag="ACG804_001701"
     CDS             19129..20361
                     /gene="pepT"
                     /locus_tag="ACG804_001701"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HFS4832633.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            20493..21401
                     /locus_tag="ACG804_001702"
     CDS             20493..21401
                     /locus_tag="ACG804_001702"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFS4832634.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            21436..21708
                     /locus_tag="ACG804_001703"
     CDS             21436..21708
                     /locus_tag="ACG804_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HFS4832635.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            21719..22765
                     /locus_tag="ACG804_001704"
     CDS             21719..22765
                     /locus_tag="ACG804_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhN family protein"
                     /protein_id="HFS4832636.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
BASE COUNT         7705 a         3984 c         5016 g         6157 t
ORIGIN      
        1 agatgtttac gaatgaaata aaaatcatgc tttatgtgga cgatgtagaa aaaaatgcaa
       61 cgttttggag agcagttggc tttgcggaaa aagatcgtca agaaatggat gggacgctta
      121 taattgaagt aggagttgag gacagtcaaa cctcatttct gttatatgat cgagcatttg
      181 ttgagtccca ttcacctggc acagctacta gtgccccatc tttgatgttt tacagtaaag
      241 atatctttgg actatataaa aaaatgcaga cgcaatcagt cacattaggt gatatggtac
      301 agcttggaga agaatatgtc tttaactttg ctgatcccga tggcaactac tttgcggtta
      361 caggtaaata atagaaataa agactttgtt tttctgtgcg aaacaggaaa gcgaagtctt
      421 tttaattcaa ataataatat tatgtaaaca aaaaactttc catgcgtaat tatacacaag
      481 caaataaatc gtcaaatgcg aacgccttct ttatactgtt taggaacgaa aagaaggaag
      541 gaagaaatac atggattatc aagtactgct ttattacaat tatacaaaaa tcgaagaacc
      601 agaggaattt gccaaaaatc atttagcctt ttgcaaatct ttggatctta aaggtcgtat
      661 tctagtagct gaagaaggaa taaatggtac tgtgtctgga accgttgaaa acacgactgc
      721 ctatatgaaa gcaatgaaag ctgatcctcg atttgctgat acgatgttca agatcgatcc
      781 aagcgaagga catgccttta agaagatgtt tgtaagatac cgtccagagc ttgtaagttt
      841 aaagctagaa gaggacattg atccaaacca agtgacaggt gcctatcttt caccgcaaga
      901 atttaaagaa gctattttag atgaacagac agtggtgatt gatgcacgga atgattatga
      961 atatgacttg ggacattttc gaggggctgt acgcccagat atacgcagtt ttcgagagct
     1021 tccagactgg atccgcgagc acaaagaaga atttatggaa aaacgggtag tgacctactg
     1081 tactggtggc attcgttgcg agaagttttc tggttggctt gtccgtgaag gattcaaaga
     1141 tgtcggacag ctgcatggcg gtattgctac ttatggtaag gatcctgaag tccaaggaga
     1201 attatgggac ggcaagatgt atgtgtttga tgaacggatc gctgtcgata tcaaccaagt
     1261 agataaacaa atcgtcggtc gcgactggtt tgacggaaca ccatgtgaac gatatatcaa
     1321 ttgtagcaat cctgagtgca atcgtcagat tcttgcttcc attgaaaatg aagaaaaaca
     1381 tttaggagca tgtagcatag agtgtgcgaa acatccgcgc aatcgctatg ttcaagacca
     1441 tggaatctct ccagaagaag cagaactgcg gtttacagct ttaattaaat agaaaacaat
     1501 agttttgatt gtcgaccatt tccaatatgc gctatactag cgttgaggat ggtgatccac
     1561 atgaaatcat tgatttatgc tattggggat gtccatggca aacatgagct ttttgaaaaa
     1621 cttattcact attatgatcc aaagatccat cagcttgttt tattagggga tctcaatgat
     1681 cgaggtcctc gtacaaaaga atgtttttta ttaggaaagc aattagtcga agaaacagga
     1741 gccatttacc tccggggaaa ccatgaagaa tattttttgc aatttctgca atcaccggag
     1801 gactggtatg cgccttatat gagaaatggt ggaaaagaaa cgtttgaaag cctgattcac
     1861 ccaggggcat cggaggaata ctccccaact gaaatctcga tgatgatcca atcgagatat
     1921 tcagaactga ttaaattttt agtccagcgc cccttgtatt atgaatggga aaattatctt
     1981 tttgtccatg ccggtgtgga tttgacaaag aaagactggc gtaagacaag tctaagagac
     2041 tttatttgga taagggaacc atttcatgaa gggaaaaaca atacaggtaa gacaattgta
     2101 tttggacata cgattacacc aatgctccat ggagatatgc agacaacaga cctctggatt
     2161 caggatcata aaatcggaat ggacggtggg gctgtattcg gagggtcatt gcatggggtt
     2221 gtttttgaca aggaaggtat tcttcaagat attgaatatc agaacaacga aggaccttgg
     2281 catggaatct gactaatgga aagaatgaag gagctgtgac tttgttgcgg ctctttttat
     2341 ttttatagag aatattgttt ctttcagtag tttaacccag gataaaaagt atgatagaat
     2401 aaagaagcaa tttttagcag aaaagaggca ttttaatgac ggaaaatttg aaccagacga
     2461 tcattcagct tgtacaaaaa gaactttcag actatcgtcc taagcagttg actactgtac
     2521 ttaatttgtt aaatgaagga aacactgttc cttttatcgc gcgttaccga aaagaaatga
     2581 ctggaagtct tgatgaagtc cagattcgtg aaatcgaaga gcggtatgcc tatcttgaaa
     2641 acttagaaaa acgtaaaact gaagtgattc ggctaatcga tgaacaaggg aaactgactc
     2701 ccgagttaga agcagaaatc acccaagccg tgaaaatgca acaagtggaa gatttgtatc
     2761 gtccatacaa acaaaaacga cggacaaaag caacgattgc taaagaaaaa ggacttgaac
     2821 cactcgcgaa gtggctgatg cagcttacag atggagaggt gcaatctgaa gcagaaaaat
     2881 atattgacaa agaaaaagaa gtctcttctg ccgaagaagc gttgcacggt gctcatgaga
     2941 ttattgctga acaagtcagc gataatgcaa aatttcggac ttggattcgg tcttatacgt
     3001 ataacaaagg tatgtatgtc agcaatgtca aggatgagca agcagatgaa aaaggcgtat
     3061 atgaaatgta ttatgacttt gcagaacccg tccataaaat ggtttctcat cgaatattag
     3121 ctactaatcg tggagaaaaa gaagatattc tgaaagtatt ctttcaagta gatgaagcag
     3181 caattttagc ttacttggat cgccaaatag tcaaaaatcc tgcctctcct tcttcttcat
     3241 tcgtcagaga agcctatcag gatagttata aacgctttat tcagccagca atcgagcgag
     3301 aactgcgcaa tgaattgact gaaaaggcag atgagcaagc aatcgctatt ttcggcgaaa
     3361 acctccgtaa tcttttgttg caaccgccac taaaaggtaa agttgtcctg ggatttgatc
     3421 cggcttatcg tactggatgt aaactagcag tcgtagatgc gacagggaaa gttttagcaa
     3481 tcgaagttat ttatcctcat aaacctgcag cgcaagcaaa aagagaagct gctggaccag
     3541 cttttatcca attaattaat aaatatcaag tagatatggt agctatcgga aatggtacag
     3601 ccagtcggga atctgaactt tttgtggctg agcagttgaa atccgccgac cataaaacct
     3661 attacgctat cgtcaacgaa gcaggcgctt ctgtttactc cgctagcgaa attgcacgaa
     3721 aagaatttcc gcatctacaa gttgaagaaa gaagtgctgt ttctattgcc cgtcgcctgc
     3781 aagatccttt agctgaatta gtcaaaatcg atcctaaagc tgtcggagta ggccagtacc
     3841 aacatgacgt ttctcaaaaa cgtttggctg aacaattgga ttttgttgtg gaaacagcgg
     3901 ttaaccaagt aggtgtggat gtgaatacag caagcccgca gctcttgcag catatatcag
     3961 gattgaataa aacaactgcc caaaacattg tcatttatcg tgaagaaaac ggagaattca
     4021 ccgcacgaac tcaattgaaa aaagtgccac gcttaggacc aaaagcatat gaacaagcaa
     4081 tcggattctt gcgagtccct ggtgggaaaa acattttgga caacacaggt atccatcccg
     4141 aaagttattc tattgcaaaa gaaatattaa cttcagtcca actttcagaa aaagagcttg
     4201 gtacagaaga agcagtagaa aaattgacac gattatccgt agagaaactg gctgaaagcc
     4261 tatcagtcgg agaagaaacg ttagccgata ttttagctgg gctgacacaa cctggacgag
     4321 atatgcgtga tgagatgcca gcgcccttat tacgtacaga tgtattgagt atggaagact
     4381 tgaaaccagg gatggaattg actggaacgg tccgtaatgt cattgacttc ggcgcatttg
     4441 ttgatatcgg tgtgaagcaa gacggacttg tccatatatc gaaactcagc aaaaaattcg
     4501 tcaagcatcc tacagatgtc gtgtcagtag gagatatcgt aacagtttgg atagaacaag
     4561 tcgatacgaa aaaaggcaga atcagtttga cgatgctttc cccttatgaa gagtaacaat
     4621 gaggagtaac aaaaattgac acaagaagaa ctgcagcagt tagtagaaga gatatcatta
     4681 aaaagcttcc agcttccttt caagcaccaa gcaatgttca atccacgctt acgtacaact
     4741 ggcgggcgct atcatttaaa cgatcatcat ttagatttta atgcgaagct atttgaagag
     4801 tcagacgaag agacgattgc aggaatcatc aaacatgaac tttgccatta tcatcttcat
     4861 ctagctggaa gagggtatca gcataaagat atggatttca agtatctttt gaaaaaaaca
     4921 ggagggttgc gctatgcacc agccttgacg aagaaacaga taaagatgga gtattatcga
     4981 tgccaagatt gttctgccac gatctgccgc aagagaagaa tcgatgtacg caaatatcgt
     5041 tgtggaagat gtcatggaga aatcaaatgg attgagacaa aaagagaaga ctttaatgaa
     5101 gcacaaaaaa tcagatgaaa ggatagaagg cctttggaaa aaagtgagca gaggaatcta
     5161 aaagactgga atcagctatt aaatttttta gccgcacctg aagagggaaa ttttgaggaa
     5221 ctgacggcac ctacacttat tttagctgga aactgtcttc ctatcttagc tgataaagca
     5281 gcacaaatgt atttaaatgg ccaagtagat caattgtttt tggtcggagg ggtggggcat
     5341 gcgactagaa tcctttatga gaattttgaa aagcaaggat ttcattttga agatggcatg
     5401 agtgaaagtg aaatctgtcg tcagtatcta aaagaagtct atgatttgcc ggataaggct
     5461 tttctgatag aatcgaagtc tacaaattct ggagagaacg ccactttttc actggagatt
     5521 cttcattcct taggagctgt accagaaaaa atcttattga tgaatgatcc gacactgcaa
     5581 cgcaggactc gagcaacttt tgagaaagta tggcaaaatg aacaaactat tttcgcgaat
     5641 gctgtgccat ttgtgccgga aatccttcac ttttctgaag agatcatctt tacagcaaaa
     5701 gaactgaatc atcaatggcc taaggaatat ttccatgcgc tagtattagg agaaatggaa
     5761 cgtctccatg acgatgagaa cggctatggt ccgaaaggaa aagattttat tcctcacatt
     5821 gatatatcag aggaagtttg gtcttcttac accagaatta aagagtcaat aaaaacggat
     5881 ttttctcgta cttgaccatt ttagcaagcg aatcctcctt tccaaataaa tttggttgaa
     5941 attttcaatc gtttataaga taatgaggag cgtgttgaat gtaatagcta aaagaatgga
     6001 cgctagataa gagaagagga ttcaaatgga aaatcaaaat aaattgtatc attttgttgg
     6061 tatcaaaggt tcaggaatga gctccttggc tcttgtttta catgaacaag gtctaaatgt
     6121 ccaaggatca gacattgaaa aatatttctt tacacaaaga gatttagaaa aagcaaatat
     6181 cacgattctg ccatttaacg cagataatgt aaaaccaggg atgacgatca ttgcaggaaa
     6241 tgcatttcct gattcacatg aagaaatcca gcgagcaaaa gaattaggtt tggaagtgat
     6301 tcgctatcac gactttattg gtcattttat ccaaaattat acgagtatcg ctgtaacagg
     6361 ctctcacgga aaaacaagta cgactggact gctctctcat gtattgagtg gtgtccgtcc
     6421 aacaagttat ctaattggag atggaacagg acatggtgat ccgcaagcgg aattcttttc
     6481 atttgaggcc tgtgaatatc gccgtcattt ccttgcctat tcaccagact atgcaatcat
     6541 gaccaatatc gattttgatc atccggatta ttatacaagt atcgacgatg tatttacagc
     6601 tttccaaaca atggctggac aagtgaaaaa agctattttt gcgtatggtg acgatgctta
     6661 tttacgcaaa ttaaaagcaa atgtgccgat ttattattat ggtgtcacag aaaacgatga
     6721 tatccaagca cgaaacatcg aacgcacaac ttctggttct gcttttgatg tctatcatgg
     6781 ggatgaattt gttgggcact tcactgtacc agcattcggt aaacacaata tcttaaatgc
     6841 tttaggtgtt attgcagtag cttatttcga aaaactggat ctgaaagaag ttgcagaaga
     6901 aatgctgact ttcccaggag taaaacgtcg attcagtgaa aagatcgtag cagacatgac
     6961 cgtagtcgat gattatgcgc atcaccctgc agagatcaaa gcaacgattg atggcgcacg
     7021 ccaaaaatat ccagataaag aaataattgc agttttccaa ccccatacgt ttacgcgtac
     7081 gattgcattg atggatgaat ttgcagaagc acttgattta gctgataaag tttacttatg
     7141 cgatattttt ggttcggctc gggaagaaca aggaaacgtt aagattgaag accttggagc
     7201 gaaaatcaaa aaaggtggag aagtcatcaa agaaaataat gtatctccat tgttagatta
     7261 tcatgatgca gtagtaatct tcatgggtgc tggagatgtt caaaaatttg aacaagcgta
     7321 tgaaaaactt ttaagcagca cgacgaaaaa tgtactgtaa tacaattact gcagtgtcct
     7381 tataaaaata gaaagagggg gagtggcaaa aatcttgcca agcccccttt tttgcaactt
     7441 atgataaacg gtgttcaaaa gcttgcatct gcggtaataa gcccaatcaa atcaaaaaca
     7501 tgagaagctg ttttttcttg gctgttctta ttatttgatg caggacagct ttttcacgac
     7561 ctctgtaaac tataggaatc tgttaaatca agggagcaga acttgccttt tacgctactt
     7621 ttggtacaat aatgtatgat taaaaataaa ctggagggtt tctatcttga acataggtaa
     7681 gccgagaaaa ctaggaaaaa caataaatga aatcgaggaa ggcgactcgt tatccttaac
     7741 agaatctatt gaagataacc agcttttgct gtatttggga ttgacgaatg atgcaaatcc
     7801 tttgtatatc caacatgact ttgcacaaaa aacagaatat caacagccaa tcgttccatc
     7861 agtgatgctg atggggatca tcacaagtgc aatttcaaag catcttcctg gaccaggatc
     7921 acatgttgtc aatttttctg tcaattttat tgaaccggtt ttccattatg aaacactgac
     7981 ttttcagttt gaggtcataa aagtagataa gatgaaggat gtggtgacga tttctgtaga
     8041 agcggagaat acgaacgaag atcgtgtgtt ggatgctgtc gttatggtcc aaccgccaca
     8101 agttcctgaa ttggaaatag caatcgaaag tgaaggtgaa ttgaatgaat aatccaagta
     8161 catcaatgtc aggtatcaat cgtttttatg caaaagttta tggattttta ggtatgggac
     8221 ttgcccttag tgcagtcact tcttacttgg ctctttgggt atttcctttg caattagcaa
     8281 cttttatcaa taattttcca ctaggctttg tgggtctgtg gatcgttgaa ctgattttag
     8341 taatggttct aggcgtaaaa gcacaaaaga atccgagctt agcaatcggt ggatttattg
     8401 cctactctct tttgaatggc ataatattag cggttactct tgcatactac gatattggaa
     8461 cagtaacgca agctttcttg acagctactt tgatgttcat ggggatgtct gttgtcggag
     8521 taacaacaaa aagagatctt agcggggttg gaagagcagg acaggcagct ttaatcggag
     8581 tgatcattgc actagtcttg aacatcttca ttttgagaag tagcgtagtt gagctgttca
     8641 tctccctact gttagtcgtc atctttgcag ggattacagc ttatgataac caaagcatcc
     8701 gtaatatcta tgtccagaca aacggaacag cacatagtgg aattgctgta ttcatggcat
     8761 tgaagctgta tttggacttt atcaacttgt tcttggcgtt tctgagaatc tttggacgga
     8821 acaactaaaa aagaaaaaaa ttcatcagtt ggggctatac cgaattattt ggtatggtcc
     8881 cgctttttct tttcgcattc cgcaggattc tttgttagaa tgaataagaa ctttacagta
     8941 aggagttaag aagatgacaa aaaataaatt attactcgtt gatgggaaca gtgtggcttt
     9001 tcgcgcattc tttgcgcttc acaattctct tgaacgtttc aaaaatagaa acggtcttca
     9061 tacaaatgca atctatgcat tcaatacgat gtttgaaaat gttatgcaaa aagagcaacc
     9121 gactcatgtt ctggttgcgt tcgatgcagg aaaaacgact tttcggacag aaatgtatgc
     9181 ggagtacaaa ggtggaagat ccaaaacacc tggcgaattc aaagaacaaa tgccatatat
     9241 acgtgatttg ttgacaggac taggggtaca gtattacgaa ttgcccaatt atgaagcaga
     9301 tgatattatc ggtactttgg cagaaaaagt agacaaagat caatttgatg tcgtcgtgct
     9361 ttcaggtgat cgggatttga ctcaattagc tagtaaagaa gtaaaagtgg atatcactgt
     9421 aaaaggtgtc agcgatatcg aaagctatac accagaacat gtagcggaaa aatatgatgg
     9481 gttgacgcca aaacagatta ttgacatgaa gggactagcc ggagatgcct ctgacaatat
     9541 ccccggtgtg actaaaatcg gtgaaaaaac agctatcaag ctattgaaac aatatggctc
     9601 agtcgaagga atttatgaac atatcgatga aatgaagcaa agcaaaatga aagaaaatct
     9661 gataaatgac aaagagcagg ctttcttatc gaaaaaattg gcgaccatca atacttcagc
     9721 gcctgtggat gtctctatcg actcattgaa gtatgaaggg aaaaatctcg ataaactcgt
     9781 tccgttttat aaagaaatgg atttcaatca gttcctttct aaattgaata tcgtagaaga
     9841 agaagtaaaa atggatgata ttttgtttga agtcgttcat gaattcaaag aggaaatgtt
     9901 tactacggat atggcgttgt acgtggaaat gatgggcgac aattatcata cagaggaaat
     9961 cgtcggagta gcgtggggga cagaaaagaa aatttatgtc acgaacgatc tatctgtatt
    10021 cgaaaaccga gcgttccatt cttggatcac tgatccgact cggctgaaaa aagtatatga
    10081 tgcgaaacga acttatgttg ctttaaaccg ctatactgga aaaacgaaag gaatcgattt
    10141 tgatgtcttg ctaggtgcat accttctcga tacgaatgaa aaaagcacag atatcgaagg
    10201 aatagctgct cattacggat acaacgatat ccaatcagat gaagctgtat acggcaaagg
    10261 ggcgaaaaaa ggtttaccag aagaagagga actctttttt gctcatttag cgcgaaaagt
    10321 agctgcaatc aatgcgttga caccaaaatt gagccaagaa ctggcagaaa aaaaccaaga
    10381 agatcttttc cggaaaatgg aactgccatt gtctatcatt ttggcagaga tggaaataag
    10441 cgggatcaaa gtagatgcga ctcgcttaca agaaatgaag ggcgagttct ctgctcgctt
    10501 aagagagatc gaacaaaaaa tctacgaaga agccggcgaa gaattcaatt tgaattcacc
    10561 aaagcaatta ggagtgatct tatttgaaaa aatgggatta cccgttatca aaaaaacaaa
    10621 aactggatat tccacagccg tagatgtact ggaacagctt cgtgaacaag caccaatcgt
    10681 agaggatatc ctcacctatc gtcaaattgc aaaaattcaa tctacctatg tcgagggact
    10741 gctgaaagtg atccaatcag atggaaaagt gcatacccgt tatgtccaga cattgaccca
    10801 aacaggacga ttaagctctg ttgatcctaa tttgcagaac atcccgattc gattagatga
    10861 agggagaaag atacgtcagg catttgttcc tagagaaaaa gactggctga tttattcttc
    10921 tgactattca caaatcgagt tacgcgtact tgcgcatatc tcaaatgatg aacatttgaa
    10981 agctgccttc ctagaaggtc aagatatcca tgccagcaca gcgatgcgtg tatttggaat
    11041 cgaaaaggca gaggatgtca caccaaatat gcgtaggcag gcaaaagcag tgaattttgg
    11101 tatcgtgtat ggcatctctg attacggact ttcacaaaat ctaggaatca gccgaaaagc
    11161 agcacagcaa tacatcgata cgtactttga aaaataccca ggtgtcaaag aatatatgga
    11221 aagaatcgta cgcgaagcaa aagaccaagg ctacgtcgaa acgctgtatc accgccgtcg
    11281 atatctgcca gacatcaatt caagaaatta caatatccgt tcttttgcgg aacgaacagc
    11341 tatcaataca ccaatccaag gaagtgctgc tgatattttg aaaatcgcga tgatcgaatt
    11401 ggataaacga ttaaaagaaa caggtcttca agctacgatg ctgttacaag ttcatgatga
    11461 acttgtcttc gaggtaccgg aaaaagaact tgaatcatta gataaattgg tgaaggaagt
    11521 tatggaacaa gctgtttctc ttcatgtacc actgatcact gacagcagtt ggggaaaaac
    11581 gtggtacgaa gcaaaataaa cattgtttaa gacagagcaa tataatgaag gtgaaaagaa
    11641 aaaatgccag aattaccaga agtagaaacc gttcgtaaag gattggaacg gttagtagta
    11701 ggaaaaacga ttcaaaaagt tcaggtcttg tggcccaaga tcatcgagca accagagaca
    11761 cccatctttg aggcttctct tgttggcgaa accatccaat ccattggacg tagagggaag
    11821 tttttaattt ttcatctcga tcattgtgaa ctgatctcac acttgcgaat ggaaggaaaa
    11881 tatcaattta cgaaagaaaa tacaccaatc gataaacata cgcatgtact tttctttttt
    11941 gaggatggaa gccaacttcg ctacaacgat gtacgaaaat ttggtcgtat gacaatcgtc
    12001 gaaaaaggag caagtgcaac ttaccgagga atcatgaaat tgggacctga gcctttgcca
    12061 gatagcttct tattagcaga tttcgcaaat ggactgaaaa agtcccacaa agcaatcaag
    12121 ccattgctgc tagaccaacg tctagtgact ggtctaggta atatttatgt agatgaagca
    12181 ttatgggaag cgaagatcca tccagaacaa ccggcgaaca cactgcgccc caaagaggta
    12241 gaacaattac gtctatcgat cattgatgtt ttggatcgtg caatagaagc cggaggtacc
    12301 acgattcgca gttatttgaa tgcattagga gaatcaggcg gatttcaagt agcactgcat
    12361 gtctatcagc aaactggcaa accatgtata cgttgtggaa cgccgatcgt gaaaacaaaa
    12421 gtggcacaaa gggggacgca ctattgtccg aattgtcaaa ggctaaaaat cgcaaagtag
    12481 gatttgtttt aggtttgacg ggtggaatag ctaccggtaa aagtacggca gccaaagtct
    12541 ttcagtctca tggatttcct ttgatcgatg gcgatgtgat tgccagagaa actgttgagc
    12601 ctggaacgct tgctctgagg aaaattgtat cagtgtttgg ccaagaggta ttgcagcctg
    12661 atgggcaact agatcgaggg aaacttggga tgattgtttt tccatcaaag gaaaaacggc
    12721 aaaaacttga tcagctatta gatccgttta tccgaaaagc gataaaagat caaatcgcct
    12781 ctctaagttc caatcatcct ttagtaattg tagatatccc attgctctac gaaggtcatt
    12841 atgaccacta tatggatgca gtagctgtcg tttatactac gccagaaact cagcttcagc
    12901 gtttgatgaa acgtaatcaa ctgacgctag aacaagcgca gcagagaatt agtagtcaac
    12961 ttccaatcga agaaaaaaag cagcgtgcgg atattttgtt cgacaacaat ggaacaaaag
    13021 aaatacttgt gggacaaatc gaaaattggc tttttgctaa tcgctttctt tgagtatctg
    13081 tgtcaatttt gctatcctga gtatatagaa agtgagggat agcgatggga tcattaaaaa
    13141 atcaaaagga taaagtcgta ggtaacgcaa aagaaaaaat cggcgagatg ctcaataaag
    13201 aaaatctaat cgatgaaggt cgtacgcaat cagaaacagc agaagaaaaa gaaaagcagt
    13261 accaagcaag aatcgatgaa atagaagacc agcaggcaga agaagaagcg aagcggcaag
    13321 atttgactca agaacgaaaa aatccgacac ctgatcgtag taaaacaccg ctcccagaaa
    13381 gtgaccacat tcccgatgag caaaaaatcg aggaacagcg aatgaaacac tatacaggaa
    13441 tcgaagagaa gttataaaat agtaaaaaat cgagatgtga cttgaagcag atgagaaggt
    13501 gttcatctgc ttcaagtttt ttgtgctaga tgactaaatc agcttttgtg taagttattt
    13561 ctcagtaatc aaggtgatca gtattggaaa attgaaattt agtaaggaca ggggacacaa
    13621 ttacgcatga aagtagaaaa aattgttctt atatccgtgt tttttgggta ggacagtcgc
    13681 gtttgtgatt tgtttcgtgt tataatacaa ctagttgtaa agaaagacac atcctttata
    13741 taaaatgcga tgcaagaggt gagacaaaat gagatgtccc agatgtcaac ataataattc
    13801 acgagtaatc gacagccgtc aagcagatga tggacgtgcg atccgtcgcc gtcgcgaatg
    13861 tgagaattgt tcgttccgat tcactacatt tgaacgaatt gaagctgctc cgttattagt
    13921 aatcaagaaa aacggggaac gcgaagagtt caatcgcgat aaaattttaa gaggactcat
    13981 ccgttcagca gaaaaaagac ctgtagctat ggaacaaatg gaacaaatcg tcaaccatgt
    14041 cgaaaaccgc gtacgcagtc tcggagaaaa cgaagtatcg acgaatctaa ttggtgaata
    14101 tgtgatggaa gatttagttg atttagacga aatcgcttat attcgttttg caagtgttta
    14161 tcgccagttc aaagatatgt ctgttttctt aaaagagttg caagatatcg tggataaagc
    14221 aaaagaaaat aataaagaga ataataaaga aaacaattaa gaaacaaaaa ggaggcattt
    14281 ccttggaaaa tgcttggaaa gagcttcaac caaaaaatat ttaccaagga agaaaagcgg
    14341 ctccgctgag agaagacagc aagaacgcct tgctgtatct ttatcagcca ctaatcggcg
    14401 gagaagcctt gagtatctat ttcaccctgt tatcagaaat ctctcaagaa tctggcaaag
    14461 gtcctgaagg gatgcatgca gatctgctta gtagtctagg ctgcggtatc ccgcaatttt
    14521 atgatgcaag aaaaaagcta gaaggaatcg gcttactgga tgtttatttt aaagaagata
    14581 gtgatctggg acctcgtttt atttatgagc tgttagaacc actcattcct aaagcatttt
    14641 tcaaagactc tgttctggct tttcttcttc tggaaaaagt tggtgaacga cgattccaga
    14701 agcttaccca attctttgaa cctaaaaggc atacagcaga gggatatcaa aaaatcacaa
    14761 aaaaattttt agatgtttat cgcttcaatg aagcagtgta cgctgctaat caagaaaaca
    14821 tcgaatcgct gaataaatct tttgaagaat ctgaatcagt agcattactt gaagcagatt
    14881 cgacattcga ttggcagttt ttgaatgatt ggctggcaaa aaaacatatt gcaagtcttg
    14941 atgatccaat catcaaacaa gtcgacatgt atcatcagct ttacggtttc gatgaattga
    15001 cacttggcga actgatcagt caatcttatg actttagtga acaaaaagta tctgaaaaag
    15061 aactgcaaaa agccattttg gcaatgcaga gacgtccggt gaagcaaaca aaagaaacag
    15121 ttgcggtttc tgaaaacagt aatgaaccct cgtcaaacga acatttgaca aacgcagcgc
    15181 ttcagctgat aaaagaagca cagagcattc caccgatgaa atatctggaa gcaatcaagt
    15241 cagaaaaagg cggatatgtt tctaaacaag aaaactggtt actgcaagat cttgtttctc
    15301 aatcaggtct ttccagtagc gtgatcaatg ttttgctgaa ttatgtacta gtgatcaaga
    15361 ataatgctag cttaaatgcc agttatgtaa atacagtggc aaatgaatgg gcacaaaaga
    15421 aaatcgccac agcagaagaa gcgatccagc acattcggca aataagtaat caagcaaaac
    15481 aatcaaaaca aaagaagcaa acaaattatc aaactggcaa gcgaaatgtt cgacgggaaa
    15541 agcttcctga ttgggtcaac cagccaaaag atgaaaaaca gatcagcagc gagaaaaaag
    15601 cagagattga ccgccgtttt aaagaatacc tggcaaaaaa ggagggtgat atctagtgga
    15661 agacgtaggc aaagaattga agaggatcat cagcaaacgc aattatcaag aaaagtatgc
    15721 tgaaatgatc gctgaagtct taaatgatgc ggatgttcaa gcttttctaa gcgcacacca
    15781 agaagaattg acacaagcgg atattgaaaa aagttacgct aaattgtatg aattcgtgca
    15841 agaaaagcgt aaatatcaaa aaaacgatcc aacgatgatc gctcccggct atgagccgaa
    15901 gctgacgttg aattttcatt atgtggatgt cacttatgta ccaacggaag cattgttagc
    15961 acggcaaaga caagaagaaa tcagaagccg agtaaaagca atggatatgc caaaagatat
    16021 tcaatcggct tcttttgaaa actttgaacg tacagatgga cgaggatatg cgagcttaga
    16081 agccctagat tttgtagaga aatatactgc tgatccaaaa gggtatcata aaggactgta
    16141 tctagtagga agttttggta ttggaaaaac atatttatta ggagcaacag cgagagaatt
    16201 agcgattgct ggattcacca cgacgctagt ccattttccg acatttgccg ttgagatgaa
    16261 acaggcaatc ggaaaagatc aagtggcaga aaagttagat gcagtgaaac gttcacctat
    16321 tttgatgatc gatgacattg gtgcagatgc gatgagtagt tggatacgag acgaagtatt
    16381 cggtgttatc cttcaatatc ggatgcagga acagttacca accttcttct catcgaattt
    16441 tacaatggat gaattggaac agcatttgtc cgtcactcaa cgtggagatg aagagccgct
    16501 aaaagcgaaa cggataatgg aacgcatacg ttatttgaca aaagaaatcg aaatgactgg
    16561 tcgcaaccga cgcaatggtt gaacagttga caagtccaac tgacatttga cctagtagta
    16621 aaagcaggtc agcgaatcat tatatggaca gaaatgaccg gagacaatca ccgcaacaag
    16681 taatgcagaa acttaaacgg aggatttttt atgagggcta ttttttctag tatatctgta
    16741 gttggtctat tttttctttt agcaggctgc ggtagcgcag atagcaacac aggttctgtt
    16801 gattcgattg atgcgggtca aacagtaaaa acaagcagta cgaaaacgga gagacaaagc
    16861 atatttgtcg gaacgattga aagtatcact caagtagaag cagaagaaga aacgcttcag
    16921 ttgaaactcg tcgatgtcat ggccaaagaa gatccagcga atatgggaac gtcattcagc
    16981 aatgacggag tgatcttaaa tgctactgct gaaaaaataa gcgtggacat aaatgaattg
    17041 aaaatcggtg acaaagtcca atttacatta gttgagatgc cgatcatgac gatgtctatc
    17101 ccaccgcaag ttcctggaga ttcgattatt gatgtttcat tgaacaaata accaataaca
    17161 ttttttcaaa aataagaaaa tgttgtttta tagaacgaaa aggtatattt tttaaggaga
    17221 tatgggaatt tttttattcc tagtctcctt attttatttg gaaaatgcta taattatcta
    17281 gaaggagtga agctatgaac catttagatt tatctcagcg cttagccgca gtgggtgact
    17341 ttgtccctga atccgctcgt ttagcagaca ttggatcaga tcacgcttac ttacccgttg
    17401 cattgatatt aagaggaaaa atcgaatatg cagttgctgg tgaagtcgtt caaggtcctt
    17461 atgaatcagc acgtaagcaa gtcaaaaaag atggattaga agaccgtatc accgtacgcc
    17521 ttgcaaatgg tctagatgct atccagccac aagatggtat tacagctgtc acgattgcgg
    17581 gtatgggagg ttcactgatc cgagatatcc tagaagctgg caagttgaat caacgcttaa
    17641 gcggacaaga acgtttgatc cttcagccaa acatcggaga gcgtacatta cgatcttggc
    17701 tgcaagaaaa tcagtataaa atccaatcag aaaaaatact tgaagaaaat aaaaaaatat
    17761 atgaaatcat tgtagccgaa aaagaacaaa aaccagttac ttacaatgaa atggagctga
    17821 tgttcgggcc atttctgctt gaagagaaaa gtgagatctt caaatcaaaa tggacaagag
    17881 agcttcaaca aagaaaagct atccgtgaac agctcaaaca agcagctaat caagaggcac
    17941 gtcaaaaaca aatcgagcag gaaatccaaa tgattgagga ggttttaaag ccatgacaat
    18001 cagcggacgc actttcatcc aaaagtttga aagctattgt cctcagtggc tagctgaaga
    18061 aggagaccca gtcggactgc atatcggaac attggataag ccaatccaac gagtaatgat
    18121 gacattagac gttcgtccag aagtggtcga agaagcaatc aagaaaaaaa tcgatttgct
    18181 gattgctaaa catcctccaa tctttcgtcc tgtaaaacgg ctggttactg atcagccaca
    18241 agaaaaaatg tatgcagatt tgttgaaaca tgatattgcc gtctatgcag cacacacgaa
    18301 catggatatt atttgggatg gactgaatga ctggttttgt gaacttctcg gtattgaagt
    18361 ggagagttat ttagtaaaga ctcatgagat tcattataaa aaactggccg tttatgtacc
    18421 tgtggatcat gcacagaaaa tgcgtgaagt attagctgca gctggtgctg gtacacaagg
    18481 tgattatacc ggtacaagtt ttacctcgat tggacacggt cgatttactc cggaagctgg
    18541 tgcacaacca gcgattggga aagtagggaa gacagaacaa gttcaagagg caaaagttga
    18601 ggttattttg ccggaaacta tcgaaaaaca agtgattcaa gccatgcggt cagctcatcc
    18661 ttatgaggaa cctgcttatg atcttttcgc tatagatgaa ccagtcgaaa tgtttgggtt
    18721 aggacgagta ggtgaattgc cgcaagaaat ttctatagag gcatttgtag aacaagtaaa
    18781 agaagcgttc caactagatg gactgagaat agtccagcca aaaaatgcaa aatcctctgt
    18841 gaagcgcatt gcgatttgcg gtggaagcgg tgaaaaattt tatccgcaag caatcgccca
    18901 aagagcagat gtctatatca cgggagatat ctattatcat acggctcatg atatgcaaag
    18961 cgctgggttg attgcaattg atcccggtca ttatattgaa tcgttatgca agcaacgatt
    19021 tatcgagaaa tttgaatctt ggaaacaaga agaaaattgg gatattaact ttttcgtttc
    19081 tgaaacaaat acaaacccat ttcaatttaa ttaaaaggag agaatactat gtacgaaaat
    19141 cttttgccac gttttttacg atatgtcaaa acagaaacac gctccgatgc aacaagcaaa
    19201 acgactccat cgactcagac acaagttgct tttgcgcaag aattgaaaaa agaattagaa
    19261 gagttaggct tagctgatgt tttctataat gaagataacg gattcgttat gggaacatta
    19321 ccaagcaatg ttgatcatga agtgcgttcc attggattta tttcccacat ggatacagca
    19381 gattttaatg cagtaggagt caatccacaa atcattgaaa actatgatgg cgagtctacg
    19441 atcgtactag atgcggaaga acgctataca ttgaatacaa aagattttcc aaatttgaaa
    19501 aattatgaag gccacacatt gatcacaaca gatggcagta cattactggg agcagatgac
    19561 aaatcaggga ttgcggaaat catgactgca atggagatct tgatcaataa tccttctatc
    19621 cctcacggta ccatcaaagt ggcttttggt cctgatgaag aaatcggtgt cggagcggat
    19681 aaattcgatg ttgagcaatt cgatgtagat tttgcttata cagtcgatgg tggtccttta
    19741 ggtgagttgc agtatgaaac gtttagtgct gctcaagcaa atattacgat ccaagggaaa
    19801 aatgtacatc cagggacggc aaaagataca atgatcaatg ctctacagtt agcaatcgat
    19861 tttcataatc agcttccagc cgatgaagtt ccagaaaaaa cggaaggata cgaaggtttc
    19921 ttccatttga tggcattgga tgggaatcct gaagaagctt ctatgagtta tatcattcgc
    19981 gatcatgatc gtgaaaaatt cgaagcacgc aaagcacaaa tcacacatat ccaagaagag
    20041 ttgaatcagc gatttgatca agaacgaatc aaagtagata tgtatgatca atattacaac
    20101 atgaaagaaa tcattgaaaa agatatgagc atcgtggaat tagcgaaaca agcaatgatc
    20161 gagcttggta tctctccagt gatcgaacca gttcgtggag gaacagatgg ttcaaaaatc
    20221 tcttacatgg gtattccgac gccaaatcta tttgccggag gagaaaatat gcacggacga
    20281 ttcgaatttg tttctttaca agtaatggaa aaagcaacag acgtgattgt aaaaattgca
    20341 gaattgaaca caaagagtta aaatcgaaaa agaacagctt atgacaaggc gttcgtccca
    20401 atgatggaat gtcatctgtc taaggctaaa gggcaggaca atggaattgg ttgtcccgcc
    20461 ctcttttttg aagagtaaat aggaggtaaa gaatggaaaa gctgctagtt ttttataaca
    20521 aaagttcagg gaaagatgag ggtgagaaat tagcacgctg gtttcaagat tatgtaaaag
    20581 aaaagcagcc agaattatat gtagaactag ctgaaactgg cccatcgatt gatgatgcgg
    20641 aattagtcaa gaaagcagaa gccatagaag ctgatacttt agtaattata ggtggagacg
    20701 gcacgattca tcatatcgtc caagcgttcc aaaaaacatt atctcaatac catgtcggat
    20761 tacttccagg tggaactgtc aacaaccttg cacgtgttct tgagattccc ctcaaaaaag
    20821 aagaagctgc tgacgtgatc ctggaaggca atgtacggaa aatagactat ggtcaagtca
    20881 atgatgaagt cattatctct acactgacaa tcggaatctt agcagataca gcagtttgga
    20941 tcagtcaaga agaaaaacag cgttacggct cgtggatctt tatcaagaag ttttttaagt
    21001 tattgctgaa gaagaaaaaa tatcatttgg atttagaaac agacgaggag cattggaaag
    21061 gaaaatccca actgttgaca gtcacgatgt ctaactccgt gggcggtttt acaaattttg
    21121 acgactcagc gaccctagat gatggaaaat ttcatgtaac gatcgtacct tccttagata
    21181 ttttccgatt tattttttat ttgcctagaa tcatgagagg caaattctat acgatccccg
    21241 gcattactta tttcacagcc aaacgcatga aaatccaagc gcaggaaaaa tctgtgggca
    21301 ctcgaacgga tggagacacg acagatgatc ttccagttga attatctgtt gtatcaaaag
    21361 gattaacagt ttattcacca aagaaagaag aaaaagctta gaaatagtag ttaacagaaa
    21421 gttggaagaa gagtaatgga tgtattgtta cacaatcctt tgtggtttta ccttttcatt
    21481 gtgaattttt acttattttg tctgatgggg tatgataaac atcaggctag aactagcggc
    21541 tggcgtgttc ctgagaataa tttgatattt gtcagcctgt taggcggtgg tttgggagga
    21601 ttgatctctc gaaaagtttt ccatcataaa actcggaaaa agaagtttac tataggattc
    21661 gctgcaggtg tacttgttga tttgattctc atttattttt tccattaagg agcaggagat
    21721 gtcgtctaaa ggaacgaaaa ctaaaatcat tctgaatctg cttttgctga ttgtgatttt
    21781 tgccattatt tattatttaa tcaatcaatc atttgcagat atctttgccg aattgctgtc
    21841 taccagtgtt gttgttttgg cagcggctgt tatattaggg acagtttacc aaatcgctga
    21901 agggcgctca atcaaagaaa ttgctgaacc tttcgcgccg aattttacaa cgaaagatgg
    21961 gttcttgacc tctagctata ttgcgtttta ccgaatcgtt tcgtttggta caggaacgct
    22021 gatctcggag atttattttt ataacaaaaa aggaatgaag ctatcccagg gagcaggggt
    22081 gacagcactc catatgatta tgtacaaact ggcagtgatc acttatgcat tagctggctt
    22141 ggtcatccaa ttctctcttt tttattctaa tggtccatca atgatctggt ttatcatcgc
    22201 tggtatcctt ttgacgatcg tgattgttgc ctttttattg gcgatgtccg tcagcttgaa
    22261 tgttcaaata ttttttgtca gcttatcgaa taagttattt aaaagtgagc gtttgcggaa
    22321 atgggtggat acatgcaatc agcagatcta ctctttaagg gaaacggtcc aaaccattat
    22381 ccaagacagg actgcgctat tgcggattta tctatggaat atgttaaaac ttgtattttg
    22441 gtatgtactt ccttatttga ttctgattga aaaccatcct aaaatagatt ttctactgac
    22501 catttcgttt atcagctttg cagtagtgct ttcaggggtt attcctacgc ctgctggtat
    22561 tggttccttt gaatttgtct atttgttatt attcagacca gttgttggaa cagttgacgc
    22621 agtttcttcg cttttactgt atcgtttcag ttcctttatc ttgccatttc tctatggatt
    22681 tgtgtatgtg attgctgaac ggcgaagagt gatcaaagaa gaaataatag aagtaaaaaa
    22741 agagaataaa gaaaatcaag ggtaggtctt ttataagatc tacccttttt atcaaatcaa
    22801 agaaaaacgt tatggataag ataattttac gtttgtttgg ctcttttttt atatacatac
    22861 aa
//
LOCUS       DAZUJR010000047        22005 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.047, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000047 DAZUJR010000000
VERSION     DAZUJR010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22005
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.047"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(515..730)
                     /locus_tag="ACG804_001705"
     CDS             complement(515..730)
                     /locus_tag="ACG804_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HFS4832637.1"
                     /translation="MHIKNTKTTFILSSEELKNIQGGSAVGVLGTTFSGATAGVKLCS
                     AGGPYAIAACGVGGALLGAGFSMWTGA"
     gene            complement(749..985)
                     /locus_tag="ACG804_001706"
     CDS             complement(749..985)
                     /locus_tag="ACG804_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HFS4832638.1"
                     /translation="MFKHAKCKGTKYCGNAQTVGGGNNAWGKLGQVVGGLTTGAVGGA
                     GLGTAICGPACGVVGGLYGAVAGGAAAGWDARKK"
     gene            1243..3396
                     /locus_tag="ACG804_001707"
     CDS             1243..3396
                     /locus_tag="ACG804_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0043214 - ABC-type bacteriocin transporter
                     activity [Evidence IEA];
                     GO_process: GO:0043213 - bacteriocin transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HFS4832639.1"
                     /translation="MIKSFPFVQQQDEKDCGVACLSMILKYFKTDIPIHKLRDLSGTD
                     LEGTSAFGLKKTFEKLSFDCMAIQADSEIWKERDLILPLIAHILVDNSYMHYVVIYKT
                     KGNVLWIADPANGKNRKTIEAFQKEWTGILLLPMPRETYIPIKEKVAGLSSFLPIIWK
                     QKGLVFHIVLASIFITFFGIGSSYYFQGILDFFIPNQARSTLNIISIGLIAVYLFRVL
                     FEYSRSYLLIILGQRMSMAIMLQYFKHVLTLPMNFFATRKSGEIISRFLDASKIIDAL
                     ASATLSIFLDIGMVLLVGVTLAIQNSTLFLITLCSLPFYVVAIFAFVKSYEKSNREEM
                     AAGAAVNSSIIESLKGIETIKAYSGEEKVYNRIDHEFVKLMKKSFRTVTLDNIQQGIK
                     HLIQLISSALILWLGSYFVMDNRISLGQLITYNALLVFLTDPLQNIINLQVKMQTAQV
                     ANNRLNEIFAIDSEKSNQSFEYMLSEQLFQQDITVKNVSFSYSMKAPTLNEISCTIPS
                     HSKTAIVGVSGSGKSTLAKLFVRFYEASEGSIHYGNINHLDIPFQILRDRVTYLPQES
                     FFFSGTIIENLIFGLDSPPSFEQIIEVCEIVQLNEFINQQPLRYETLLEEGGNNLSGG
                     QRQRLALARALLKNPDILILDEATSGLDTLLEHAIMNYLLNLKEKTIIFIAHHLPIAK
                     ACDQILVLHEGHLVEKGTHDELRFADGIYQKLWEI"
     gene            3365..4780
                     /locus_tag="ACG804_001708"
     CDS             3365..4780
                     /locus_tag="ACG804_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HFS4832640.1"
                     /translation="MVSIKNYGKSRRGKQFMQNNNWFEHSSIYTKQHHSFYRWVLYPV
                     ILFLCIIGLFLTFAKKEVVIRTTAQLNPEKIEKLQVPLEAKIMENFLKENQFVHKDDV
                     LVRLDCSLIENEKAQIEQENQRITQQIKMAQLFIESISKGKNLFSTDDSFGYSNQLKS
                     MLSEKESLRYALKQSELNDQKQLEVYEKTKRQLEKQIESSDSKLQEWQQVQVAWSNNQ
                     SLKDFSKEMMANYENWQEQLNNVSDDQKNQVKLTISASINEQIEQLKKEVEQYQSEKA
                     KLVKPTTSENDRISQTEKGKQELEQAITTVKQTVTELNEKQEKNQSVIKSLDDQLSKG
                     ILKAPVSGTVHLNEETKGQAELAKGTVLAEIYPIHEKSKMKFTALLPANESTYIKEGM
                     KVHFKLDQKGGAPITIDGTLDEISENSTATEKGVFYAVKGTLKTTQSFPFRYGLTGEL
                     SLIVGEKTYWQQIVDVFLNKK"
     gene            4813..5847
                     /gene="sppA"
                     /locus_tag="ACG804_001709"
     CDS             4813..5847
                     /gene="sppA"
                     /locus_tag="ACG804_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HFS4832641.1"
                     /translation="MNKRRWIAVGVACGLLLLSIIVALIPGKDKEEASNTTLTGINKI
                     FYGSNEITEETLEEGASNKKIVKLSVNGVIADTGESNLFSREQYNHQNFLTQLKKIQE
                     DKAVKGVLLEVNSPGGGIYESAEIAKEMAKIKKLDIPIYTAFKNTAASGGYYISAGSD
                     KIFATEETTTGSIGVIISGLNYSGLLEKLGVTDATYKSGALKDMMSPQHKPSEEENKV
                     IQEFVMSAYDRFVNVVAKGRNMDTNAVKELADGRIYDGNQAVENGLVDQIGYSEDALD
                     SLKKEKKLTDATVIEYKNDTTGFASSWLGNKIAEWQGLKATTSDRVISVFEKLGFSDT
                     PKPMYYYGGL"
     gene            5849..6370
                     /locus_tag="ACG804_001710"
     CDS             5849..6370
                     /locus_tag="ACG804_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HFS4832642.1"
                     /translation="MNKKSGIETLPNYVFAGFWLRFFAFLIDLICISIITHATIGLFY
                     KIMGLESDKSIITFYGIASLAIYLTYFVLLTKLNSGQTIGKMIFGIRVVSFEEKELSW
                     QTIFIRECICRFILKNFVFQIGYLVAAFTPKKQHIGDYFSNTSVVVIRSLEAINYGQK
                     ISNSKTLNLERIK"
     gene            6367..6753
                     /locus_tag="ACG804_001711"
     CDS             6367..6753
                     /locus_tag="ACG804_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HFS4832643.1"
                     /translation="MNKRKTEFILILISGITGILCSLLALMGGMFLSSIDSTTLNTTE
                     LTSKDIDMLVNLSGNVVLFGGITLVFSIMIFIIGFLVRKNQKTVVYGISLLILSIIPF
                     FLLTLLWVIPGVLGIIAGLMLLIRKS"
     gene            complement(7249..7321)
                     /locus_tag="ACG804_001712"
     tRNA            complement(7249..7321)
                     /locus_tag="ACG804_001712"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7286..7288),aa:Lys,seq:ctt)
     gene            7702..8271
                     /locus_tag="ACG804_001713"
     CDS             7702..8271
                     /locus_tag="ACG804_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HFS4832644.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            8258..9118
                     /locus_tag="ACG804_001714"
     CDS             8258..9118
                     /locus_tag="ACG804_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFS4832645.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITPEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            9308..10012
                     /gene="yycF"
                     /locus_tag="ACG804_001715"
     CDS             9308..10012
                     /gene="yycF"
                     /locus_tag="ACG804_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HFS4832646.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            10017..11852
                     /gene="walK"
                     /locus_tag="ACG804_001716"
     CDS             10017..11852
                     /gene="walK"
                     /locus_tag="ACG804_001716"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HFS4832647.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVILSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            11849..13165
                     /gene="yycH"
                     /locus_tag="ACG804_001717"
     CDS             11849..13165
                     /gene="yycH"
                     /locus_tag="ACG804_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system activity regulator YycH"
                     /protein_id="HFS4832648.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            13166..14035
                     /locus_tag="ACG804_001718"
     CDS             13166..14035
                     /locus_tag="ACG804_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HFS4832649.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            14090..14899
                     /locus_tag="ACG804_001719"
     CDS             14090..14899
                     /locus_tag="ACG804_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFS4832650.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(15002..15631)
                     /locus_tag="ACG804_001720"
     CDS             complement(15002..15631)
                     /locus_tag="ACG804_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFS4832651.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAASDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            15801..17093
                     /locus_tag="ACG804_001721"
     CDS             15801..17093
                     /locus_tag="ACG804_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFS4832652.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQHLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(17169..17831)
                     /locus_tag="ACG804_001722"
     CDS             complement(17169..17831)
                     /locus_tag="ACG804_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFS4832653.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            18056..18340
                     /gene="groES"
                     /locus_tag="ACG804_001723"
     CDS             18056..18340
                     /gene="groES"
                     /locus_tag="ACG804_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HFS4832654.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            18391..20016
                     /gene="groL"
                     /locus_tag="ACG804_001724"
     CDS             18391..20016
                     /gene="groL"
                     /locus_tag="ACG804_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HFS4832655.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDATIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
     gene            complement(20105..21244)
                     /locus_tag="ACG804_001725"
     CDS             complement(20105..21244)
                     /locus_tag="ACG804_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4832656.1"
                     /translation="MWVEQTKDGQFKFIERYVDPYTEKTRKKSTTLTSNSPQAWKKAQ
                     KILDKKIKEALENYNKSDITFGELYKEWYEYYKQHVKRTSYLKVPMMMKHVSKHISDD
                     TIVRNIDETLINKMIEDMYTFGDLSLNYTKQTKTTLSVMLNYAIDRKYIQRNPALAVK
                     IHPKKVEEEKRKLSMDKKYLEKEEIDQILKQLYSNPRRKLHGIIAEFLYLTGLRYGEL
                     LALQMKDYGEGKISINGTLDYTSVKMDNAIKTTPKNTYSQREVQLSNRAKELIESVIA
                     DNILAGRPTNPDQYIFISTNGTPLTLHSFNAVLHKVEEELELEKNLSSHIFRHSHVSL
                     LSELGVPLKAIMERVGHSDANTTLSIYNHVTKKAKQQVIDKLNRL"
     gene            complement(21355..21939)
                     /locus_tag="ACG804_001726"
     CDS             complement(21355..21939)
                     /locus_tag="ACG804_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HFS4832657.1"
                     /translation="MAKKVMGQDGKMYKVSKPFYKKVWFWVLAVILIIIIGSALNGGS
                     DSNKASDNGGEKVTKSSTSASSSKEEKSDTFYKIGDTVKVGDAEYTLNSVELTDERNQ
                     FEENQPAQVVKITYTVKNDGDSDIPVGTDVEVYGPDDKKSETYANENTMGSVAPGKQM
                     DVTAHFTLNQKGEIEIHFSPLVSFEKAAIFKATV"
BASE COUNT         7322 a         3621 c         4389 g         6673 t
ORIGIN      
        1 tcttttcttg tttttattaa gtaccataaa ggggaattaa aattaaatgt atggtggaag
       61 atgcgaaaga tttggcaaat tctactaatt tttagaaagt gtttttcatt ttttagttaa
      121 aaaatttgtc ctgtcaagtg caatcctatg attgtacttg ataggatttg agataattac
      181 tttcctgttt ttataaattt aacttgcagg aacaggcttt aatgcacatc cgacaagtac
      241 attaccaata cctcctgtaa cggccgaaat aggtcctcct gcagcaccaa ctacagcgct
      301 gcaagtcctt ttgtaaaaat atctctacca ttacatttcc aaagaatttt tatctgactt
      361 taataaaaga taaaaattta atataattat aaaaactagc acaagaagct ttagtaaaaa
      421 gttctgtcca ttccaaactt ttgaaaagat aaagaacata cctatgttcg taatcgacac
      481 aaaccaatct tgaggtttga tattttttaa ttgtttacgc accggtccac atgctgaatc
      541 cagcacctaa taaagctcca cctacaccac aagcagctat tgcataaggt cctccggctg
      601 aacaaagttt tactcctgct gttgccccag aaaaagtagt gcctaaaact cccacggcac
      661 tcccaccttg aatatttttc aactcttctg aagataatat aaatgttgtt tttgtgtttt
      721 taatatgcat actacttatt ctcctttttt atttttttcg agcatcccag ccagctgcag
      781 cacctccagc gacagctcca tataaccctc caacaacacc gcaagctggt ccgcaaattg
      841 ctgttcctaa acctgcacca cctactgccc ctgtggtaag tccacctaca acttgcccca
      901 attttcccca agcattattg cctccaccaa cagtttgtgc atttccacaa tacttagttc
      961 ctttacattt tgcatgttta aacacgcttc tttaaataat attttttacg gtgctactgt
     1021 aacatacgta tttgattaac agtaaaaatc ttcctgaaac ttatcaagtt tattcttgaa
     1081 tagtaaaatt tccaaaataa atttgattca ggaatgaaaa agttagtgtt caagaactgt
     1141 tttcaaagtt tttgtggaat tatgagacaa tattttcact gtattaaagc tatattgaga
     1201 atttttctat aaaaattttt tagaaggagt tgtgttagat aagtgataaa atcatttcct
     1261 tttgtgcagc aacaagatga aaaagattgt ggtgttgctt gcctttcgat gattttaaaa
     1321 tattttaaaa ctgatatccc gattcataaa ttacgggacc tatctgggac tgatttagag
     1381 ggtacttcag catttggatt gaaaaagaca tttgaaaaat tgtcttttga ttgtatggct
     1441 attcaagcag atagtgagat ctggaaagaa agagatctta tcttaccatt aattgcacat
     1501 atattggttg ataacagcta tatgcactac gttgtaattt ataaaacgaa gggaaacgta
     1561 ctatggattg cagatcccgc taatggaaaa aatagaaaaa cgattgaagc gtttcaaaaa
     1621 gaatggacag gtattctttt attacctatg cctagagaaa cttatattcc tattaaagaa
     1681 aaagtagctg gattaagttc ttttttgcct ataatttgga aacaaaaagg attagtattc
     1741 cacatcgttt tagcatcgat tttcattacg ttttttggca taggaagctc atattatttt
     1801 caaggtattc ttgatttttt catccctaat caagcacgtt caactttaaa tataatttcc
     1861 attggcttga tcgctgtcta tttatttcgg gtattgtttg aatatagtcg tagttatctt
     1921 cttattattt taggacagcg aatgagtatg gcaattatgc ttcagtattt caaacatgtg
     1981 ttaactttac caatgaattt ttttgctacg agaaaatcag gggaaattat ttctcgtttt
     2041 cttgatgcca gtaagattat tgatgcttta gcaagtgcta cgttatcaat atttttagat
     2101 attggtatgg tgttgcttgt tggggttacg ttagctattc agaatagtac gttgttttta
     2161 atcactctat gctctttgcc tttttatgta gttgcaatat tcgctttcgt gaaaagctat
     2221 gaaaaatcga acagggaaga aatggcagcc ggtgcagctg taaattctag tatcatagaa
     2281 agtcttaaag gaatagaaac aattaaagca tatagcggtg aagagaaagt atataaccgt
     2341 atagaccatg aatttgttaa attaatgaaa aaatcatttc gtacggttac gcttgataat
     2401 attcaacaag gaattaaaca tttgattcaa ttaattagca gtgcattaat tttatggcta
     2461 ggttcttatt ttgttatgga taatagaatt agtctaggtc aacttatcac atacaatgct
     2521 ttactagtat ttttgacaga tcctttacaa aacattatta atttacaagt gaaaatgcaa
     2581 acggctcaag ttgcaaataa tcgtttaaat gaaattttcg cgattgattc agaaaaatcg
     2641 aaccagtctt ttgaatatat gctttctgaa caattatttc aacaagatat cactgtaaaa
     2701 aacgtttcat tctcgtatag catgaaggcc ccaacgttga acgaaatttc atgtacaatt
     2761 ccttcgcaca gtaaaacggc tatagttgga gttagtggtt ctggaaaatc aactcttgca
     2821 aagttatttg ttcgttttta tgaagcatca gaaggatcga tccattatgg aaacattaat
     2881 cacttagaca ttccttttca gatattacgc gatcgagtga catatttgcc tcaagagtca
     2941 tttttcttta gtggaacaat cattgagaat cttatattcg gtttagatag cccaccaagt
     3001 ttcgaacaaa taatagaagt ttgtgagata gtccaactaa atgaatttat taatcaacag
     3061 ccattacgtt acgagacatt gttggaagaa ggtggaaata atctttcagg agggcaacga
     3121 caacgattag ccttagcacg ggctttatta aaaaatccgg acatattaat tttagatgaa
     3181 gcaactagtg gattagatac cttgttagaa catgcaatta tgaattatct cctcaattta
     3241 aaagaaaaaa cgattatttt tattgcgcat catttaccaa tagcaaaagc atgtgatcaa
     3301 attttagttc tccatgaagg gcatttggta gaaaaaggaa cgcacgatga acttcgtttt
     3361 gccgatggta tctatcaaaa attatgggaa atctaggaga gggaaacaat ttatgcagaa
     3421 taataattgg ttcgaacatt ctagtatcta tactaaacaa catcatagct tctaccgttg
     3481 ggtgttatac cctgtaattc tttttttatg tattattgga ttgtttttaa cctttgctaa
     3541 aaaagaggtt gttattcgga caacggctca attgaacccc gaaaaaatag agaagttaca
     3601 agtgccatta gaagctaaaa taatggaaaa cttcctaaaa gaaaatcaat ttgttcataa
     3661 ggacgatgtg ttggttagat tggattgttc tttaatagag aatgaaaagg ctcagataga
     3721 acaagaaaac caacgtatta ctcaacaaat aaagatggct cagctattta ttgaaagtat
     3781 aagtaaagga aaaaatttgt tttcaacgga tgacagtttt ggctacagta atcaattaaa
     3841 gagcatgttg tcagaaaaag aatcactccg ctacgctttg aagcaaagtg aattaaatga
     3901 tcaaaagcaa ttagaagtat acgaaaagac aaaaagacaa ctagaaaaac aaattgagag
     3961 ttcagatagt aaattacaag aatggcaaca agtacaggta gcttggagta ataatcaatc
     4021 attaaaagat ttttcaaaag aaatgatggc aaactatgag aattggcaag aacaactaaa
     4081 taatgtttct gatgatcaaa aaaatcaagt gaaactgaca atttcagcaa gcataaatga
     4141 acaaattgag caactaaaaa aagaagtaga acagtatcag tcagaaaaag ctaaattagt
     4201 taaaccaact acttctgaga atgacagaat tagtcaaacg gaaaaaggaa agcaagagct
     4261 agaacaagca ataacaactg taaaacaaac agttacagag ctaaatgaaa aacaagagaa
     4321 gaaccagtca gttatcaaaa gtttggacga tcaactttca aaaggaatac taaaagctcc
     4381 tgtatctgga acggttcatt taaatgaaga aacaaaggga caagcagaac tagccaaagg
     4441 aacagtgctt gcagaaattt atccgatcca cgaaaaatca aaaatgaaat ttacagcact
     4501 tttacctgcg aatgaaagta cctatattaa agaagggatg aaggttcatt ttaaattgga
     4561 tcaaaaaggt ggggctccga ttacgatcga cggaacttta gatgaaattt cagaaaattc
     4621 tactgccact gagaaaggtg ttttttatgc agtgaaagga acgttaaaaa caactcaatc
     4681 gtttccgttt cgttatggat taactggaga gttgtcttta attgtaggag aaaaaacata
     4741 ttggcaacaa attgtcgatg tgtttctaaa taaaaaataa ttatttttac taagaatata
     4801 ggaggagttt atatgaataa aagaagatgg attgctgtgg gagtagcgtg cggattattg
     4861 ttactatcca ttatcgtcgc gctaattcca ggaaaagata aagaggaagc atcaaataca
     4921 accctaacag gaataaataa gattttttac ggatctaacg aaatcacaga agaaacgtta
     4981 gaagaaggcg catcaaataa aaagattgtc aaactatccg tcaatggagt tattgcagat
     5041 acaggtgaaa gcaatctttt tagtagggaa caatataacc atcagaattt tttaacacag
     5101 ctaaagaaaa ttcaagaaga caaagcggtt aagggagtgt tattagaagt aaattcacct
     5161 gggggaggaa tatatgaaag tgctgagatt gctaaagaaa tggcaaaaat taaaaagcta
     5221 gatattccta tctatactgc atttaaaaat acagcggcaa gtggagggta ctacatttct
     5281 gctggttcag ataaaatatt tgctacggaa gaaacaacaa ctggatcaat tggtgtcatt
     5341 atttctggtt taaattattc tggcttatta gaaaaacttg gcgtaactga tgcgacgtat
     5401 aaaagtggtg cattaaaaga tatgatgtca cctcaacaca aaccttcaga ggaagagaat
     5461 aaagttatac aggaatttgt gatgagtgct tatgatcgtt ttgtcaatgt tgtagcaaaa
     5521 ggaagaaata tggatactaa tgcagtgaaa gaacttgcgg atggaagaat ttatgatggt
     5581 aaccaagcag tagaaaatgg gttggtggat caaattggtt actctgaaga tgcattagat
     5641 tccctaaaaa aagagaagaa attaactgat gcgacggtta tagaatataa aaatgacaca
     5701 actggctttg cttcttcttg gttaggtaat aagattgctg aatggcaagg gctaaaggca
     5761 actacatcag atcgtgtaat ttcagttttt gaaaaacttg gattttctga tactccaaaa
     5821 ccaatgtatt actatggagg gctataaaat gaataagaag agtggcattg aaactttgcc
     5881 taattatgta tttgcgggat tttggttacg attttttgct tttcttattg atttaatttg
     5941 tattagcatc atcacccatg ctactatagg tctcttttac aaaatcatgg gactggaatc
     6001 tgacaaatcc attattactt tttatggtat agcgtcatta gctatttatt taacctattt
     6061 tgtacttttg actaagctga attcaggaca aacaattggg aaaatgattt ttgggataag
     6121 agtagtgagc tttgaggaaa aagagctaag ttggcaaact atctttattc gtgagtgtat
     6181 atgtaggttt atattaaaaa attttgtatt tcaaattggg tatttggtgg ctgctttcac
     6241 gcccaagaaa caacatattg gggattattt ttctaacacg tcagtggttg ttattcgttc
     6301 attagaagct attaactatg gtcaaaaaat ttctaattct aaaacactta atctggagag
     6361 aattaaatga ataagagaaa aacagagttt attttgattt taattagtgg aataacaggg
     6421 attttatgta gtcttttagc attgatgggt ggtatgtttc tatcttctat tgattcaact
     6481 actttaaata ctacagaact aaccagtaag gatatagata tgttagtcaa tctaagcggg
     6541 aatgttgttt tatttggagg aattacccta gttttttcga taatgatttt cataataggt
     6601 tttttagtaa gaaaaaatca aaaaacagtg gtctatggta ttagtttact cattttatct
     6661 attattccat tttttctttt aacattattg tgggtaattc ctggagtttt aggtattatt
     6721 gcgggattga tgcttctaat aagaaaatct taattaggca atgtgtagac aacgtgaaac
     6781 gattaatcaa ttaaaagcta aatacgtttt gagaaatgat aacttgtagt cgatggaaga
     6841 catgtagata aaaaaactac gtgtctttta tttattctaa ttttttcgaa aaaaagacac
     6901 tctctgattg ttgtattaat ggaaaagggg aaagcagcaa gtaaatttag tttttctatt
     6961 aaatattctt cactttttaa ccttttatag tacttagatt taatcctata tgtttagaga
     7021 gttcattggc agcatgattt tgcaaagctt ctcgaattat tgttatatta gaaactttac
     7081 tgttcataat tatgcttctt ttttaactca aagtccaaag ggctacagtg gactttgagt
     7141 taaaaataaa aagccctagt tattttgaaa aataaaaaaa gaacagcgta aatgttttcg
     7201 aaatgctttc gcaccaacat ttacctgttc cgtgggtttg gcacccaatg ggccgtgagg
     7261 ggctcgaacc cgcgacccgc tgattaagag tcagctgctc taccaactga gctaacggcc
     7321 cgtacaaaaa gtacttaata atagtagcac taagaatttt aaaatgcaag actacattta
     7381 aagaaaatca gaaaaatctt tacttcctta taggaaatca ttcatagatt attcacattt
     7441 gctcgctatt atataagcat accaacaaac aaagttcttg caagagaaca aaccctaaca
     7501 cttttttcat tttttactcc tttcccgccg tctccccggc gggtctcctg ttcttaacga
     7561 taaaagacaa gaaggcttag ccttcttgtt ttttgttttc atggaatccc gctaatcaaa
     7621 tcacctagtt aaagcaacta gattgaatgt ttatcataag tctgatatca tgtttatgaa
     7681 atgaaaaaag gagcggttat gatggaaaaa atgcgtcagc aattaatgga gtgggggaag
     7741 gaactagaaa cattccgtct gcctcactgg gaagaactcc ctgacttaga actttatatg
     7801 gaccaagtca gaacgttagt tgatcgttat ctttcacctg tgatacaagg agaaaagcat
     7861 ccattgctta cctcttctat ggtaaacaat tacgttaaac taggtttgat accagcacca
     7921 gttaaaaaaa gatataacaa agaacacgta gcatttttac ttgcaatcac tacgttgaaa
     7981 caagtattga ctattcctga aatcaaagaa gggatattgt tccaaggaaa aacagtagga
     8041 attcgtgaag cctataatct attttgcgat gaacaagaag cagctgtgtg gatggtcagc
     8101 caattagcac aaggtaaatc tcatccgcaa aaattcgacc aggcaacccc tgtagaatat
     8161 attgctgtaa gagcggcaac tttatcgttt gcaatgaaac ttcttgcgga aaaaacgatt
     8221 gttctagaaa ccgaatattt aaaagaggag aaaacaaatg aaaaacaata aaatcgcaat
     8281 tttagtagat tcaggtacgg atgttccaga agaattgata aaaaaatacg agatgtatat
     8341 gatcccattg aaaattattt ataaagatca ggtatataca gataaaattg acattacccc
     8401 tgaagagatc tatcaacgtt tgccagagga aatccctggt acatctttgc cggatggtga
     8461 gtcgatcaca gaaatctttg agcaaatcaa aaaagacggt tatgaaaagg tacttgcggt
     8521 aacaatttcc agtggattga gcgggacata taatgtggtt cgtttaattg cacaacagca
     8581 agaagaattg gaagcatatg tactagatac gaaaaatatt ggtattggtg caggtttttc
     8641 tgcgatccaa gcagcaaaat ggctggaaga aggagtagaa tgggatcaac tgatcagtaa
     8701 tctgaatgag ttagtcgaaa gaacaaaagt tttctttaat gttgcgacat tggaatatct
     8761 tcaaaaaggt ggacggatcg gtttagttgc ttctattgta ggaaccgctt taaagcttaa
     8821 cccaatcatc tcatgtaatg aagaagggat ttattacaca gtaggaaaag ctaggggacg
     8881 taaaaaaagt ttggataaaa cggttgctta cgtcaaagaa aaaatcggta atgcaaaggt
     8941 cttcaactta gctgttgccc atggggatgc gaaagaagaa gcaattgaaa tggaagcgag
     9001 acttaaaaga gagttcccac aagcaaacca aatctacttt ggccagattt ctccggcatt
     9061 agtagtccac actggtccgg gattattggg tgtcggtgta caagttttag aaggataaat
     9121 caaaaaaagg aaacactgag gtgaaaatca gtgttttcct tttttattga agttagaaca
     9181 aaaaataata aagtattttg cactttcatt ttaattttct cttttgtttt ataggcaaag
     9241 atgaaacaaa agcagaaata cggtataatg agaaggtatg acaataatat ataagaggtg
     9301 gctctttatg aaaaaagttt tagttgtcga tgatgagaag ccgatttcgg atatcgtcaa
     9361 attcaattta gccaaagaag gctatgacgt ttatactgca tatgatgggg aagaagcctt
     9421 ggaaaaagtt gctgaggtag aacctgattt gattttactt gatttgatgc tacctaaaat
     9481 ggacggctta gaagttgctc gtgaggtacg caaaacttat gatatgccga tcattatggt
     9541 aacagccaaa gattctgaaa ttgataaagt cctaggctta gagttaggcg ccgatgatta
     9601 cgtgaccaag ccattttcca accgagaatt agttgcacgt gtcaaagcaa atcttcgtcg
     9661 cggtgccacg gctgcgaagg aaccagaaga ggcagcacct gcggaattga cgattggtga
     9721 tttgacgatc catccagaag cttacatggt gacgaaacga ggagaaacaa tcgagttaac
     9781 acatcgtgaa ttcgaactac tcttttactt ggcgaagcac cttggacaag tgatgacaag
     9841 agaacattta ttacaaacgg tttggggtta tgattatttt ggagatgtac gaacagtgga
     9901 tgtaactgta cgtcgtttgc gtgaaaagat cgaagataat ccaagccatc caaattattt
     9961 agtgacacgt cgtggtgtcg gttactattt gcgtaaccca gaacaggagt aattggatga
    10021 aaagaaaagt ccgctttttt cgatcagtca attttaagat cgctattacc tttattctga
    10081 ttttattgat ctcgatcgaa attattggtg cctactttat acgtggttta gaacgttcca
    10141 cgatcaatac atttattaaa gatatgaatc aaacggtgga atcattagca acaacaatca
    10201 gcccggaatt gaatcgaaaa gataatgcag atgatgaaga ggtaaatgcg aatatcaaaa
    10261 gatttattga aaacagtgcg actagcgata tcatcgaaat acgggtcgtt gacgaaaaag
    10321 ggatcatccg aggaacaacc gatgtcaatg aacaaagcgc tgtgggaaag aaaaatgatt
    10381 atgttgatat caatgatttc acgactaaac gttatgttgc tttagataac gacgataaac
    10441 gggtgaatat caatgttcaa ccgatcctgt ccccgaccgg cgatgccgtt atcggggctc
    10501 tttacgtcaa aagtaatatc gaacaaaaat attcggaaat caataacaca gcagtcattt
    10561 tctttactgc ctcactaatt gcggcattta tttcaatgat cgtatctgtt ttagttgctc
    10621 gttcgattac acagccgatc ggtgaaatga gagaacaagc cattcgaatc gctagaggag
    10681 actacagtcg gaaagtcaaa gtgcatggac aagatgaact tggacagctg gctgatacct
    10741 tcaatcagtt agctgaacgt attgaagaag ctcaagatac aatggaagct gaacgcaatc
    10801 gtttggatag cgtgctatcc catatgacag acggcgtcat tgcgacagat cgcaggggta
    10861 aagtcattac gatcaatgat atggctgttt ccttgctaga tatcaaaaac gaggaagcaa
    10921 tcggacaatc gattttgaca cttttagata tcgaagaaga atatacgttg cggaaattat
    10981 tagaagatcc aaacgaaatg gtacttgacc gttcaaccag tacattggaa agtgatcaga
    11041 tgatcttgcg agtagacttt tctatgatcc gtcgcgaatc aggttttatc agcggattag
    11101 tagctgtctt gcatgatgtg acagaacaag aaaaaacaga acgggaacgt cgtgaattcg
    11161 tctctaatgt ttcccatgaa cttcgtacac cgttgacaag tatgcgtagt tatatcgaag
    11221 cattgagcga aggtgcgtgg aaagacgagg aagtagcacc aaattttttg aaggtaacgc
    11281 tagatgaaac agaccgaatg attcgaatga tcaatgacct cttaaatcta tctcgcatgg
    11341 atacaggtaa tacccagctt caattagaat atgtcaattt caacgagtta gtgaattttg
    11401 ttcttgaccg gtttgatatg atggtgggaa atcaggaaaa aaattataag atccgtcgtg
    11461 aatttacgca aagagatctt tgggtcgaag tagatacaga taaaatcatc caagtagtcg
    11521 ataatatcat gaataacgcg atcaagtatt caccagatgg gggaacgatt acttgtcgct
    11581 tattagaaac gcataataac gtgattttaa gtatcaccga tcaaggattg gggattccta
    11641 aaaaagatct gaaccgagtg ttcgagcggt tctatcgagt agataaagca cgtgcaagag
    11701 cacaaggtgg gacaggactt ggattagcta tttctagaga agtgattaag gcgcatcgag
    11761 gcgctatttg ggcagagagc aaggaaggaa aagggtcgac tttttatatc tcgctgccat
    11821 atgaacctta tgaggaggaa tggtgggaat gagaatctct gaaaaagtcg ttcgtatagg
    11881 actcattttg atggttgcgt taagcatata cttctcttat gcaatctggc tgagcccagc
    11941 aggaaaaagt tcaatcaacg tagatgagac aaacactcaa atgatcgagt ctcaaagcaa
    12001 tcgaaaaact tccgaagtct ttcttccgct tcatgttaca tggcaccatt cgggaatgat
    12061 ccaagaaacc aacagtgaaa atctcgtgta ccgattgcaa ttgatcatcg ataaagcaag
    12121 atttggaaag ctttctgaag tagtttcagg agacaaatca cagtttgaac aggtgaaaaa
    12181 tctgaactct ggttttgagt tggcctataa tgcgcctttt ttgctaagag aatacaagga
    12241 agcatttgat ttagatttag atgtgtcgaa cttggcaaaa gaaagcgaaa atatgtattt
    12301 tactagaata caattcgatc aaggaaataa aaaaatccga tttttgaatt attcgaacca
    12361 tctcgtatat gaagcaaata tttcgttgaa ttggacagat atcaataaag aattaacagc
    12421 aaaagacaca aaatggacag aaatgacaac agaaccatcg acgatcgaca cgcaatatgc
    12481 tacgaaacat tcgatcaaac tgaagaagta tagttatatc ctgtcacagc aaccctatac
    12541 actttttaga aatgcttttt tccagaaacc agatagcgtg aaaaataatg atgaaagcaa
    12601 tgaattgatt ttttacggtg ggaatgaaac aatgtctatc cattcggaaa cgcaagtagt
    12661 tgattttcgt ggagagctgc cagagaaaaa agaaaatgct agtgtatttt ctgaaagttt
    12721 cccctatatt agcaaattag gcagttcttt agggaacctc agatattttg accgcagtga
    12781 caatacgatc gattatcgga tattcgtgga aggcttcccg gtttttggga cagacagcag
    12841 aggacagatt ggtgtggaag ttggcggtga aacgaatggt tctgtgcaag tgaatatcca
    12901 aaccagtttg aatacgattc aagtgccgat accttcagac gaagaagtag aacttgcaag
    12961 tacgaatgaa atcatccagc agttaaaagc taagggagca gatagcaaca agattggttc
    13021 agtgatcgtt ggctatacat ggcaaaatgt caaagaaacg aatcgtgtcg ttgatctctt
    13081 acctgaatgg tatgtgaaat ataaagataa ctggtattca gctaacgacc ttctggaaaa
    13141 attacctgga ttggaggcga attaattgga tttcaaaaaa atcgaatgga tatttttcgt
    13201 cgctttttta gggttgaatg tgtttttatt cagcagttat catgacgcgg tataccaaga
    13261 aaacaatgtc attcgctcta atcagactga atcaatccaa caacgtctgg ctagcgacga
    13321 tatcacttac acggggaaga tttcgtctga gaacaagcaa ggctattatc ttagcgcgga
    13381 gcagaccaat cttagcactt cattagcgaa ttatcgcaag gctggtaaaa gcggcttgct
    13441 ggcaagtggt gtgtttttag acggtgatgt tttgacgaaa tctttatcca gttcagatgc
    13501 tgaaaagaac gtgatcgatc cagataaaat tagtagttcc ttggaagatt ttttatctaa
    13561 caaagacaat attttattcg gtaatgatta tgtgtacacg aaaaactttt ctcatttaga
    13621 agaagaacca ctagaaatcc aagcaagcca agagtatgaa ggcatcccat tcaatgatga
    13681 tacagcaaaa atcgttcttt ctttagaaaa aaacgataat gattatagca tcacgaaata
    13741 catgcagacg catttatctg atatcgagca gctgcgcgaa aagacggaac tgtatacgga
    13801 agaggaagca atcaatacat tgtacatcaa taacaaaata ccaagaggat caaaaatttt
    13861 atggcgtcag ctagcttatt cctgtattct gaaagtccgg gaaaaaaatg tgtatgttcc
    13921 tgtttggcat gtagcgatcg aaacaagcga taaagtggtc caaattgaga gcgtcaacgc
    13981 tttcagcaat acgatcgtga caaacaatac tgtaccaaaa gtggaagatc aataaaaaag
    14041 cgagtataat gaaaaaagtt tacaaagtaa gaagggaagt aggagtcaaa tggctgaaga
    14101 aaaaccagct tttaaaatca gtatcctagc aagtggaagt tcgggtaatt cactttatat
    14161 cgaaagtgaa aaaaaacggc ttttggtcga tgcaggactt agcggtaaaa aaatcacttc
    14221 cttgatggct caaattgatc ggacaccgga ccaattagat ggaatacttg tgacgcatga
    14281 acatcgagat catatacatg gcgtgggtgt cttggctcgt aagtatcatt tggatgtttt
    14341 tgccaatcag cagacttggg aagcgatgga accactgatt ggaaatgtac cagtggaaca
    14401 aaaacatcta tttgagatgg ggaaagtcag aacattcggc gatatcgata ttgagagttt
    14461 cggcgtctcc catgacgcag cggctccgca attttatcgt ttccataaag aaaatcggtc
    14521 attcgtcatg ttgacggaca ccggatattg cagtgattat atgcgaggtg tcattgaaaa
    14581 tgccgatggt tatttgatgg aaagtaatca tgatcttgag atgttacgca tgggacctta
    14641 tccgtggaat ttaaaacagc gtattttagg agatagagga catctttcca acgaagacgg
    14701 tgcacttgtc atgactgatg tgatcggtaa tcggaccaaa cgaatctatc ttggccatct
    14761 tagcaaggaa aacaatatga aagaacttgc tcatttaaca atggaaaatg ttttgaaaga
    14821 aaaagatttt ggcgttggac atgattttga aatctatgat acagatccag atgaagcaac
    14881 tgagctattt tcgatttaaa cagttcaatc aataaaaata taaaaagcag aagataaaat
    14941 caatcagggt tggttttatc ttctattttt atttttttag catattaaaa aaataaccgt
    15001 attatcgact gactacactg atgtgctgct tttcatgttt ctcatccagt atctcatcta
    15061 ctaatgcaat cgcgtaatct gccatgctga tcgtactgtc gctagcagcg tttctttgta
    15121 aataatcatc acttaacaaa taagtacctg tacgtttgcc atgtggatca aataaagaag
    15181 ctggactgat ataagtccaa tgtagatttt tagattgttt caattttaac aatccttcgt
    15241 acatattgaa agctgttgga tagaagggtg catttttagg tacttggtca atcatacgag
    15301 tcgtcttttc tgtatctaag aataacgaag aggcaccccc aacgacaatt aagcgtgtat
    15361 cggttccttc aagcatctca atcaaatggg acaaagaagt ttgatgcatt tcttcttttc
    15421 ctttgggagc gttgaaagca tcaacgacaa catcaaaaga tgcaagatca gtagttgtca
    15481 actcaaataa atccttttgt ataaacggaa catctgatgg caatttttct ggatgacgca
    15541 cgattgccgt cacgtctaaa tctctggaca atgcttcgtc taaaataaat gaacctgcat
    15601 ggccagtagc tccaatgagt gcaattttca taaaaaacct ccttttttat tcctgtccat
    15661 tgtaagcagt tgctgaatat tcgtcaaaga atccgatttt tgaaaagctc agtgcgcatt
    15721 cctttcatgg ttcgtgatca ttgggtatag ttaaattaag aaaactgatt gataaaaata
    15781 gaagttgaag gagataagaa atgaaagagt ggttagatcg tgccttttta ccaatgataa
    15841 catctgttgt gaatcttaga cccttaactg ctttgcgtaa tggaatgact tacacgatcc
    15901 caataattat tgttggctcg ctgtttttct tatttgctca ttttcctgtg gattacatcg
    15961 ctcagtggat agacaaaaca ggattttcta tgtattttac acaagtatac caggctacat
    16021 ttgatgtgat agccttttgg atcgtttttg ccattgcata cgcttatgca aaagaagaag
    16081 acatcgatcg cttaccagtc ggcataacag ccttgtctgc ttatctactg cttattcagc
    16141 cactaaatac tcagatagat actgtctgga caggtgctga agggatacta ggagcagtta
    16201 caactgggct catcatcgga tggggctatg cacgtttagt aagacttgcg aaagggtgga
    16261 agcaaagaga gaagatacct gaaaatgttt ggcagtcttt tacttcattg attccaatca
    16321 ttgttatagt cacttttacg cttatcggtt cagcggtttt tcaacatttg ttcagaatga
    16381 ctgttgttca aggagtatgg acatatgtcc agcttcccat tcaatcgttc atagacacgt
    16441 tgtttggtgt gcttttatta ggtttttttg ttccgttttt atggttattt ggtcttcatg
    16501 gatctgcgat ggtcaatggg ttggttagtc ccgtcttgca agcgaattca ttagcaaatg
    16561 cagaaatctt agcctcagga caagagttga cggtggcaaa tggcggacat atcgttactc
    16621 agcaatttct cgatcagttc atgacggtta cgggtgctgg attgacgtta ggggctgtat
    16681 tttttatgac ggtttttgcg aaatcgaaga aatacagaga attaggaaat cttgctcttt
    16741 taccagcctt tttcaacatc aatgaatcaa ttattttttc cacaccgatc gtgatgaacc
    16801 cgatgatggc tgttcctttt attttcgcac cggtcgtttc aggattgatt acctattccg
    16861 ctttatattt tggattcgtt cctttattta cagcagtcca agtcccttgg acaacaccgc
    16921 cgatcctctc gggtttctta gtaggcggag tgcctgcagc gattttacaa ggtatcgtgt
    16981 tgtcaattag ttttttcatt tatttcccat ttttgaaaaa aatagattct gcaaactgca
    17041 aaaaggaaag acagacaaaa aatgatggag cagcagaaaa gatgaacgac taaaaaacaa
    17101 aaatactcct gtcgctttag attgggaaaa tcaccaatct aggatgacag gagtatttat
    17161 agtcatgttt atactagccc tttttggaca gctaattgaa caagaacaac taatgtgttc
    17221 attcctacgt gtgtgatcat cgatgtccag atccgaccag ttgctttgta ctctaggctg
    17281 aagaagaaac ctaggaaaaa gtagattagc agatgaccat cattatgagc aaacgcaaac
    17341 agcaaagagc tgatcactgc tccgacccaa aaatttgaat atcgactgat gatccccagt
    17401 atactgcggc ggaatacgaa ctcttccatg atgggtccag caacagttgt cgccaaaata
    17461 aaagcgggtg cttccatgat catctggatg atattttgtg tattctcgga aggggttgct
    17521 ttgccaaaca atacagattc taacatgaca gcgatgcttt gcagaatcaa tgcgacaaag
    17581 attccaacca atccataaat aacaatcttt ggagcagaag ctttttttac cgctgattcg
    17641 atcgctaagg gttcacgttg cttaaaataa aaaatagcta ggacaacggc gcctagtata
    17701 tacatgactg cagttgctgt gatcaattca gacgtagatt ttacaagtcc tatcgaagct
    17761 aggatcaagg gtgagataaa aattagacca tagcaaaaaa tgctgaggaa gctatatttt
    17821 tttaaagaca tgtaattcct ccttttaagg gataacaagc atgcaaggca agcttatatc
    17881 gattgatttc aattatatca taatttcaat aagcagctgt cagaataaaa tttcttttct
    17941 ttgatttaaa agcttgcaaa aaagagggag aatgagtatt attaaaaatg taggttagca
    18001 ctcgaaggtt aagagtgcta acagattaaa aaaagagtta tcggagggat ttatcgtgtt
    18061 aaaaccatta ggtgatcgcg tcattatcga agtcgcaaaa gaagaagaaa aaactgtcgg
    18121 aggaatcgtt ttagcttctg ctgctaaaga gaaaccccaa actgggacag ttgttgcagt
    18181 cggtgaaggc cgtttgttag aaaacggtga aaaagttcct gccgctgtaa aagcaggcga
    18241 ccaagttatg ttcgaaaaat acgccggtac agaagtaaaa tacgaaggaa aagaatatct
    18301 gatcgtcgca ggaaaagata tcatggcgat tgttgagtaa atttggaaga taaaaaaata
    18361 atcaaaaata atcaatgagg tgaatcaatc atggcaaaag aattgaaatt tgcagaagac
    18421 gcacgcgcag ctatgttacg cggggtagat aaattagcag atacagtgaa agtaacatta
    18481 ggacctaaag gccgaaatgt cgtactagaa aaatcttacg gctctccatt gatcacaaat
    18541 gatggtgtga cgatcgcaaa agaaatcgaa ttagaagatc attttgaaaa catgggtgca
    18601 aaacttgtat cagaagtagc atcaaaaaca aatgatattg caggagacgg tacaacgaca
    18661 gcaactgttc tgacacaagc aatcgttcgc gaaggtttaa aaaacgtaac tgcaggtgct
    18721 aatcctctag gcattcgtcg cgggatcgaa ttggcaacaa aagcagcagt cgaagaattg
    18781 cataatatct caactgttgt tgattcaaaa gaagccattg cacaagtagc agctgtttct
    18841 tcgggttctg ataaagttgg acatttgatt gctgatgcaa tggaaaaagt tggaaacgac
    18901 ggtgtcatca caatcgaaga atcaaaaggg atcgaaacag aactagatgt tgtagaaggt
    18961 atgcagtttg atcgtggtta cttatcacaa tatatggtaa cagataacga caaaatggaa
    19021 gctgttctag aaaacccata tatcttgatc acagacaaaa aaatctctaa catccaagat
    19081 attctgccat tgttagaaca aatcttgcaa caatcacgtc cattgttgat tattgctgac
    19141 gatgtagatg gtgaagcatt gccaactctt gtattgaaca aaatccgtgg aacattcaac
    19201 gtagtagctg taaaagctcc tggtttcggc gatcgtcgta aagcaatgct tgaagatatc
    19261 gctattttga caggtggtac agtaattact gacgatctag gtttagaatt gaaagatgca
    19321 acaatcgaaa acttaggaaa tgcttctaaa gttgttgtag ataaagacaa tacaacgatc
    19381 gtagaaggtt ctggagaaaa agaagcaatc gaagctcgtg tgcaattgat caaaaaccaa
    19441 attgctgaaa caacttctga ttttgaccgc gaaaaattac aagaacgctt agctaaatta
    19501 gcaggtggtg tagctgttgt taaagttggt gcagctactg aaacagaatt gaaagaatta
    19561 aaattacgca ttgaagatgc attgaatgct acacgtgccg cagtagaaga aggaatggtc
    19621 tcaggtggtg gtacagctct agtgaacgtt atcagcaaag tttctgctgt agaagcagaa
    19681 ggagacgtgg caacaggtat caagatcgtt gttcgtgctt tagaagaacc aattcgtcaa
    19741 atcgctgaaa acgctggtta tgaaggatca gtgattgttg ataaattgaa gaacgtggaa
    19801 ctaggcactg gtttcaatgc tgctactgga gaatgggtaa acatggttga agcaggtatc
    19861 gtagacccaa ctaaagtaac acgttctgcc ttgcaaaatg ccgcttccgt ttctgccttg
    19921 ttattaacga cagaagcagt cgttgcagat aaaccagaac cagcagcgcc agcagctcct
    19981 gcaatggatc catcaatgat gggcggtatg atgtaggaat taaaagagaa cccttatatt
    20041 acagggttct cttttctttt tttgttttat tttaagtaaa aggggcaaaa aaggggcaga
    20101 aatatcaaag cctatttagt ttatcaatta cttgttgttt tgcttttttg gttacgtgat
    20161 tgtaaataga cagagttgta tttgcatcag aatgtcctac acgctccata atggctttaa
    20221 gaggtacgcc taattcagat aatagcgaaa catggctatg tctaaatata tgcgatgata
    20281 gatttttttc taattccaac tcttcttcta ctttatggag tacagcgtta aatgagtgca
    20341 gcgtaagcgg agtgccattt gtagatataa atatatattg atcgggattg gtgggtctac
    20401 ctgcaagaat attgtcagct atcacacttt caatcaattc ttttgcacga ttggataatt
    20461 gtacttcacg ttgtgagtaa gtattttttg gagttgtttt tatggcgtta tccattttta
    20521 cagatgtgta atctaaggtc ccattaatgg aaattttacc ctctccatag tccttcattt
    20581 gcaaagccag caattcccca tatctcaaac cagtcaaata tagaaattca gctattatgc
    20641 cgtgtagttt tctgcgagga ttggaatata actgtttcag tatttgatca atttcttctt
    20701 tctccagata ttttttatcc atagaaagct ttcttttttc ttcttccact tttttaggat
    20761 ggattttaac tgctagagca gggtttcttt gaatgtattt tctatcaatt gcatagttta
    20821 gcataacgga tagagttgtt tttgtttgct ttgtgtagtt cagtgagaga tcaccaaaag
    20881 tgtacatatc ttcaatcatc ttattaatga gtgtctcatc aatgtttcta acgattgtat
    20941 catcgcttat gtgcttagaa acatgtttca tcatcattgg aaccttcaaa tagctagtac
    21001 gtttaacatg ctgcttataa tattcatacc attctttata cagctcacca aaagtgatat
    21061 ctgatttatt gtaattttcg agtgcttctt taattttttt atctagaatt ttctgagctt
    21121 ttttccacgc ttgtggtgaa ttacttgtaa gtgttgtaga tttttttcgt gttttttctg
    21181 tataaggatc tacatatctt tcaataaact tgaattggcc atctttggtt tgttcaaccc
    21241 acacttttaa catctcctat catttgctat aataggcata acaaatagac ctatataggt
    21301 ttgttttcta aaagcacgct cttactctgg acggtggggc gtgtttttta tttattatac
    21361 agttgcttta aaaatagctg ctttttcaaa tgatactaaa ggagagaagt ggatttctat
    21421 ttctcccttt tggtttaacg tgaaatgagc agttacatcc atttgttttc ctggagcaac
    21481 agatcccatt gtattttcgt tggcatatgt ctctgatttt ttgtcatctg gtccatatac
    21541 ttccacatct gtacctacag ggatatctga atcgccatca ttttttacgg tataagtaat
    21601 ttttactact tgtgcaggtt ggttttcttc aaattgattt ctttcatcag ttagttctac
    21661 actatttagt gtatattcag catcaccaac ttttacagtg tcaccaatct tatagaaggt
    21721 atcgcttttt tcttctttag aagatgaagc agaggttgaa gatttagtta ctttttcgcc
    21781 accattatca cttgctttat tactatctga tccaccattt aaagcagaac caataattat
    21841 aattaaaatt actgctaata cccaaaacca tacttttttg taaaaaggtt tactaacttt
    21901 atacattttt ccgtcttgac ccataacttt ttttgccatt taaatattcc tcacttcttg
    21961 ttataatata tttgcgatct cagaaatgag gtatgagtcc gtgtg
//
LOCUS       DAZUJR010000048        21993 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.048, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000048 DAZUJR010000000
VERSION     DAZUJR010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21993
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.048"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            202..1167
                     /locus_tag="ACG804_001727"
     CDS             202..1167
                     /locus_tag="ACG804_001727"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFS4832658.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGDDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(1266..2438)
                     /locus_tag="ACG804_001728"
     CDS             complement(1266..2438)
                     /locus_tag="ACG804_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4832659.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMPTIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(2425..3570)
                     /locus_tag="ACG804_001729"
     CDS             complement(2425..3570)
                     /locus_tag="ACG804_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4832660.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(3584..4508)
                     /locus_tag="ACG804_001730"
                     /pseudo
     CDS             complement(3584..4508)
                     /locus_tag="ACG804_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            4625..5704
                     /locus_tag="ACG804_001731"
     CDS             4625..5704
                     /locus_tag="ACG804_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFS4832661.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            5701..6329
                     /locus_tag="ACG804_001732"
                     /pseudo
     CDS             5701..6329
                     /locus_tag="ACG804_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
     gene            complement(6439..6666)
                     /locus_tag="ACG804_001733"
     CDS             complement(6439..6666)
                     /locus_tag="ACG804_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFS4832662.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(6769..9357)
                     /locus_tag="ACG804_001734"
     CDS             complement(6769..9357)
                     /locus_tag="ACG804_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HFS4832663.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(9377..10036)
                     /locus_tag="ACG804_001735"
     CDS             complement(9377..10036)
                     /locus_tag="ACG804_001735"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFS4832664.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVAQHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(10085..10588)
                     /gene="trmL"
                     /locus_tag="ACG804_001736"
     CDS             complement(10085..10588)
                     /gene="trmL"
                     /locus_tag="ACG804_001736"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008175 - tRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HFS4832665.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(10809..11675)
                     /locus_tag="ACG804_001737"
     CDS             complement(10809..11675)
                     /locus_tag="ACG804_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HFS4832666.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            11784..12425
                     /locus_tag="ACG804_001738"
     CDS             11784..12425
                     /locus_tag="ACG804_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HFS4832667.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(12487..13848)
                     /gene="mgtE"
                     /locus_tag="ACG804_001739"
     CDS             complement(12487..13848)
                     /gene="mgtE"
                     /locus_tag="ACG804_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HFS4832668.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(13866..14765)
                     /locus_tag="ACG804_001740"
     CDS             complement(13866..14765)
                     /locus_tag="ACG804_001740"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFS4832669.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(14767..15564)
                     /locus_tag="ACG804_001741"
     CDS             complement(14767..15564)
                     /locus_tag="ACG804_001741"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HFS4832670.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(15542..16246)
                     /locus_tag="ACG804_001742"
     CDS             complement(15542..16246)
                     /locus_tag="ACG804_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HFS4832671.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            16377..16952
                     /locus_tag="ACG804_001743"
     CDS             16377..16952
                     /locus_tag="ACG804_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HFS4832672.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            17070..17747
                     /locus_tag="ACG804_001744"
     CDS             17070..17747
                     /locus_tag="ACG804_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClpXP adapter SpxH family protein"
                     /protein_id="HFS4832673.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
     gene            complement(17826..19634)
                     /gene="pepF"
                     /locus_tag="ACG804_001745"
     CDS             complement(17826..19634)
                     /gene="pepF"
                     /locus_tag="ACG804_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HFS4832674.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSDAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(19810..20808)
                     /locus_tag="ACG804_001746"
     CDS             complement(19810..20808)
                     /locus_tag="ACG804_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA family protein"
                     /protein_id="HFS4832675.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(21034..21687)
                     /locus_tag="ACG804_001747"
     CDS             complement(21034..21687)
                     /locus_tag="ACG804_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HFS4832676.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
BASE COUNT         6492 a         4699 c         3814 g         6988 t
ORIGIN      
        1 cttttttgtg tttttcggtc ttcggacctt tttcattttc ctagacttct gctataataa
       61 ccaagaatta attttgtaac agattttttt gaaaaaacaa gtttctttca ttcaaaaaat
      121 agaaaaagct tgctaattat tggttaacca gcaaacagga gtattaaaat atcttgtttt
      181 attgaatagc aggaggaaat catgaaattc cattatcata tattgatcaa tccatcggca
      241 ggcagcggaa atggctataa agtagcagaa agaattttac cggtattaaa aaataagcat
      301 attgactata cacttcatta tagtgaatac aaaggacacg atgctgagat tgctgaaact
      361 ttggcaaaag aaacattgat tccttggata gaagaagaac agaaaacaat cgatactttc
      421 ccccttttga tcatcgtagg aggtgacggc accttacatc aggtacttga tactttctat
      481 cagatggaag tagaattccc agttgcttat attccagcag gttctggaga tgattttgct
      541 cgaggggcag gccttccaaa aaatcccaaa aaaggacttc agctgatttt agcagctcaa
      601 tcaccagaaa aagtccacat aatggcttat gaagaaaaaa taagtgaaaa aaaaggaata
      661 gctgttaata atttcggtat aggattagat gcagctatcg tccatgcgac aaatcattct
      721 tccacaaaaa agcgattgaa caaatacaac ttaggatcat tttcgtattt attctctatt
      781 ctccgtgctt tattcactca aaaaggattt ccaattctgg tagatgcagg aggaaaacaa
      841 ttaagttttt caaacgcatt tttatgtaca gcaacgaagc atcctttttt tggcggagga
      901 atcgcgattg ttccaactgc tgatgcgtct aaaccagtca ttgattttgt cgtggtcgaa
      961 cgaatcaatt tctttaaaat cttgtggctc attcttttac ttatacagaa aaaacaattg
     1021 aaatcgaaat atttccatca ctacacaaca aacagattac gtatcgtttc aacaacaccg
     1081 caacatggtc aagaagatgg agaagaaatg gaaaaacgac cttttgatat cacaataacc
     1141 acaactaaac agttgttttg gtgttaataa aagaggtttt gtcagaagct acatctggaa
     1201 caccgtttat tcggaaaaaa ggactgtgac acgacttttg tcacagtcct ttttttacta
     1261 tgcagttaat tctttgccca attgggttgc catcgatagt ttctttcttt acccaaaata
     1321 aattggatca ttgaaaacac cgcagcaaaa gcaactaaga cacaaccatt gaaccaaaaa
     1381 gattctgcaa atgtttgatt gtaactgagt gtttcactga tcaagttatt attttgaaca
     1441 aaccaatatg ttggtgtgaa tgccgctatt ttgctaacca tttctggcaa gtattctgct
     1501 ggtacaaaca ccccaccgat aaagcaactg cctgtgataa aaatatcttt gatcccaccg
     1561 ctggtttctg agttttttac caatgaagtg atacaagccg aaaagctaat gatcggcaat
     1621 aaaaacaaga aagtatttaa aatatgatac cataccgtta tatcccacga ggtgtggatc
     1681 actaacagaa ccattagaag taagaagcca ctgaacaaca gcagcgagta actaatcaaa
     1741 ctaaaggtta ctttgcgatt caagtttcgt ttggtaatgg gcgcactctg gtttcgttta
     1801 ctgatctctt tgcgattaaa tgctagattg atgacgctga aaccgctaaa aatggataga
     1861 aacaacccat aagacaagaa attaaaggtt gtgcccgtca acagcttttt catccgctga
     1921 ctatatcccg cacttagctc aacttctcca gtaaccgaga gtgccatttg tgtctgttcc
     1981 atagctgcat cgattgtttt atcttcttct tgaaacagaa tcagtgtttg caaaaaggtg
     2041 ttcacttgct gtgtaacaac tgttttagaa aaggcatctg ggcgactctg tatcttgatc
     2101 gtcggcatct ttcctacttc gacttgttcg gtaaagtctg caggcagatg taagataatg
     2161 tttacacgat taaaataaag agcatcatcg atttcttttt gtgaggttcc atccaatgta
     2221 acgactgttt ccttgtcatt caaatattta cgaaggccat cgactacagg cgactcttct
     2281 tcactaatca aggcgatttt cgcatcttgc agagaggtat tttcaacatc aatattttgc
     2341 gcaaaaaaga atgtggcaac aacagtgata attacaccta tcagtaaatt cgatttattt
     2401 gctttaagca atgtccaaat cgttttataa agcgtcataa cgcacccctc tttccatcca
     2461 agcatttcct aacgcaaaaa ggaaaataaa tccgatcaac catagaagat tggtataaaa
     2521 actagccaaa tcagtgtaga aataaagttt atacaaactt tcgctgatca agttgacgag
     2581 atttaattga ccaacaatcg gaatatgaag atcaatccaa tacttcactt gttccgaccc
     2641 catcatacca gcaaaaaagc tcatcgcaat cgtcactgaa atcaagatgc tatccttttg
     2701 caccagattc atttttggta tcaaattacc aaccaatgta cctaacaaaa tcgcacacaa
     2761 cgaccccaga gcggtaacaa tcatcaacca ttgccaacgt tcaccaaagt ctacttgata
     2821 gataaaacga aagacagcta acataatata aatctctgtc aaaacaatcg taaagcttgc
     2881 tgccaaatta gcgattgaaa ctaacgattg ctttctagga atcaaggaca agcgaatacc
     2941 atttgacgat tgatttgctt gctgatcctg tacattgcgg accccccaca tcgtcccgta
     3001 gagaatcgcc attccaatca gagtgaagaa ataaaaactt ttgaaactca tattacgacc
     3061 tgcatgaact tcttgaaaag atacttcttg ttcaaaaaca gtcatgatgg gcgcgagatc
     3121 aacgttctcc acttctgcca ctttactcga aattatacca atacgctgta aaaattgatc
     3181 catgacgttt ttcatcaacg tctgactcat tcctgcttga cccacatgga gcgaaacaga
     3241 tgaaccatca atgagataaa aaccagccaa atcatctgca tttagctttt cattcgcttc
     3301 tacttccgat agttcctgta cttcaaataa tggtttatca ttgacttcga cttgttctaa
     3361 gactgtggta aaattttccg aaagcgctgt ttgatccgct ttgattacaa ttccagtatt
     3421 aatcgtttcg agattgccac cttgatcaat ctcgccaaag gccgccataa acatcaatcc
     3481 taaaagaatt ggaaaggcca atgtccaaaa caacatggat ttatttcgca gcagtatttt
     3541 tgtgcgatat ttataaaaat gccaaaacat tatttcccct cctctagtct ctcaaatcct
     3601 tgccagtaat ctctaaaaag acatcattca aggacgcttc tttggttgct atttttccgt
     3661 aactgatctt ttcttcttgt aagattgtaa gaatcggcaa caatactgta tttagttcag
     3721 tagttgttac ttggagctga ccttttttat aagcgattcc atcagaagct attgttcgct
     3781 gacaacacgt tttctgggag taatgggatg tcgatcgtca aacgatccgc cgtccgtacc
     3841 atatctttta gagattcttt ggttccttta gcaatcacct gtccttgatc catgatcacg
     3901 atctggtcgc aaagaatttc tacttcttcc atgtaatgtg ttgtatagac aatggttgct
     3961 ccttgtcgat tcagctcctt gatactttct aaaattttat tccgactttg ggggtctaca
     4021 gctactgtcg gctcatctaa aaaaattaac cgcggcttgt gggcaatccc acatgcgatg
     4081 ttcaaccgac gtttcaagcc accactaagt tctcctggac gaaacgaaac atatttttct
     4141 aatcccacta attgaatcac ctcttcaatc aaggctttcc ttttctcttt ttcggaaaca
     4201 tataaaccgc aaaaataatc gatattttct tgcacactta gttcgtcaaa gaccgcaacg
     4261 tcttgaggaa cgaccccaat cattgccttg acagcataat tttcaggagt cattgttgtc
     4321 ccgaacaatt taatggttcc tttgtcataa tttaacaaag aaagcataca gttgatggca
     4381 gtcgatttcc cactgccgtt tggtcctaac agacctaaga cttctccttc ttgtacttgc
     4441 agatcaaaat gattcaatgc tacaaaatct ccatagcgtt tgactaattt atcaatttcg
     4501 ataatcatca tgaaaaactc cttccaaatt tcttgttgat ctgactataa taaagtgcaa
     4561 gaaaagaaac tagtgacgat tggctaaacc acacatgaca tttgtcacaa tgaaggagtc
     4621 tgctatgcat aaatctcggc tactcaacga aactagcttt ctactggtta tctcattgct
     4681 tttgctggta agtcaaggat tcgttgctat gcaagttatc tatttattga tcgccgtttt
     4741 attcactggt gtcagttatt tactgcctac aaagccaaat tggattttcc aagttattct
     4801 atttctttta tgtgcctttt tacctgatct tgtcctgttt ctgccagcga cgatgcgagt
     4861 gatcgcccct gaagaaagcc accttgatta cttgtttttg ttaggttttt tgttgatttc
     4921 gacggttggt aatcatcccc ccatcaaggt cgcctttgtc gtaattttgc tgtttttttc
     4981 cttttactta cgaaaaaaag atcaacgaac gaccgatctt gagaaaaagt acattgtctc
     5041 caaagatact cattgggaaa aacaacaaga gttatcggaa caaaataaag cattggccct
     5101 gtcacaagaa acacaattag ccttgcaaat tgtggaagaa cggaaccgaa ttgcccgaga
     5161 catccatgac aatgtcggtc atctgctgtc aagtgcgatt ttacaaattg gtgcgcttga
     5221 aatgatcaat caagaaccaa aactaaaaga accattagaa aatttaagtg ccaccgttca
     5281 cactgggatg gatcggattc gtcaaagtgt ccatgacctc catgagacat cgatctcttt
     5341 tcaacactcc ttagagtttc tgatcgctga ttttccttct tctgttacga ttgaaggaaa
     5401 cttgtttgaa ggattgaatg aaacgcagca aaactgcttc ttaatggtca tcaaagaagc
     5461 cttaaccaac agtatcaaac atagtcatgc caaaaccgtt gttttacatt ttcgaacgtt
     5521 gccggccttt tatcgcttgc aaatcacgaa tgatggcacc agcccacaaa aaaattctgc
     5581 tcccggtatt ggtttgaaaa cgatgcgtca acgtgttcaa gaacaaaagg gacaagtcca
     5641 tattttccaa gaaaaccagc aatttcagtt aacgatcatt ttaccaaggg agggacacca
     5701 atgataacag tagtcattat tgagatgatc catttgtgac gaaatcgtta caaaccattt
     5761 tagaaagcac gaaagagatc cgtgtgttag gcattggtca ttgtgccaag gatgcgctag
     5821 tcttatacga aacccatcgt cccgatgttt tgctgacgga catccgcatg cctaaacaaa
     5881 cgggcatcga tgctgccaaa gaaattttgg ctaaatttcc caaagccatc cttttgcttt
     5941 tgacgacatt caaagatgaa gaatacatcc gcgaagcatt ttccatcggt gtcaaagggt
     6001 atttaatcaa acagaacttg caagcgatta ttccttctgt caaatccgct tataatggac
     6061 aggccgtatt tggtaatgaa atcatcgaga ctttcactca aatgatgaag aataaaccga
     6121 cgattgatag tcatgcttat gcttctttta gtgaacgtga gcttgcaatc atcaaagaag
     6181 tagctgccgg gaaaaacaat aaagaaattg cagatgcctt gtacttgagt gacggcactg
     6241 ttcgcaatta catcagccaa ttactagaaa agctagattt acgggatcgc acgcaattgg
     6301 ctatctattt ttatcagcat ttgcaataag tcttatctaa cacaaaaaaa cctgaatgat
     6361 gctccttcgc atcattcagg tttttttcac atcttctatt caattgtccc gcaaaccatt
     6421 tcctcacgat tgaaagaatc aaggattcgc agggctgcca ggattcgttg gattgttcgg
     6481 cgtgttaggc ggaaaaatag gcgccttgtc taacgttttt tctagttttg attcttcacg
     6541 atcgtctcgt tctacatcag gactttcatt caatttgaat tctttttcca tctcatctaa
     6601 ctttttaaag tcattgccag attcttttgc taatttcgct aatttatctt cggtttcttt
     6661 agccataaag taacgccccc cttttgattt cagcttagca tatcacactg aaaaaacaaa
     6721 agaaaacgct aaccaacgat catttttagc tatttctcat ctttaaaatc aagcattttt
     6781 tgccggtata aaatcgtagg gagaactgtt ttccatacca atcatcggat ctactaactg
     6841 gttatcgatc acttctgctg taagaacgaa atctttagaa acagcaggtt ctacctcttc
     6901 tttcttttct tctccaacaa atgaagaaaa cagatctggt tccactgttt ccattacttg
     6961 gtttttcgtt tcattcgtcc cactgtcatc ttctacaggt agcttttctt ttacaacccg
     7021 tggctctttt gtatagttcc catcttcaaa tggatcattt ccgaccaaag aatcttcata
     7081 agctgctagt ttggtccgga gagtgatatt cattttatca ttatccatga tccttgattt
     7141 caacgtagtc atccggcttg ctgattcatt cgctacacaa gtgacatagg cttgctcttc
     7201 ccctaacaaa atcaacagtt ccttactgcg agtcactgcc gtgtagagca aattacgctg
     7261 aagcatccgc tgatattgat ggaccatggg caaaataacc atcttgaatt cactgccttg
     7321 tgatttatgg attgagcaac aataagaaag agtgatttta ttccattcgt ttcttttata
     7381 agtgacctca tttgcatcaa actggataac taattcatcc actttatctt cagaatcttt
     7441 tgccaagatg atacccgtga tttctcccat atctccattg aatacattca attcgggagt
     7501 attgactaat tggaggactt tgtctcctat ccgataaacg gtgtcgttcc aatgtacttc
     7561 cttttttcca ggtttccctg gattgaatat ctcctgcatc attttattta acgcatcgat
     7621 ccctgcaggt ccccgataca ttggtgctaa tacttggata tcttgtgcac ggaatccctt
     7681 atttttcgct ttttccacaa ttttagagat caagggttca atttgataag catcacttcg
     7741 gaaataggaa cgatcttttt gattctttgt gaaatctttt ggcagacgtc cttctttgat
     7801 ctcatgggca agaggaataa tactagaacc atcaccttgc cgataaatct gattgagttc
     7861 cattttggga atttgttcga tttccaaaag atcatggagt acttgaccag gaccgacaga
     7921 gggaagctga tctttgtctc ctactaagat aacttgcata ttcgtcggaa tcgctttgaa
     7981 taatgtgtta gccagccatg tatcgaccat agacatctca tcaacaatca aaagtccgcc
     8041 ttctaattct ttcgtactga ctgaaggtgt tttttcccgt ccattcagcc ccagaagacg
     8101 atggatcgta ctggcaggca gacctgtcgt ttcgttcatt cgtttagctg ctcggccagt
     8161 tggtgctgca agtagaatag gaaaaatttc ttgggtatat tttgaaggat ccaattccag
     8221 tccgttcaac tctgcaaaaa gattgacgat tccgttgatc acagtagttt tccccgtacc
     8281 tggtcctcct gttaaaataa atagagggga acggattgct tcagcgatag cttgttcttg
     8341 cgaaggtcca tactgtatgc cgaatatttt ttcgatacgc cgaatattct tctgcacttc
     8401 tttttcagga taatggattt cttttttacg actgagaagg cgctggatcg aattaccgat
     8461 cccccattca gaaaagtaca aactgttttc gtaaagatta gtctcttctt gttgtatctt
     8521 tccttcttca acaagttgga taattacagt agcaacctga tcaggctgga tttcaattgg
     8581 gcgacttgtt tctaaaatac ggatcgtttg ctgaagcaat gtctccgccg gtacgtatgt
     8641 atctcctgtt tgaactgcat gctgaaaaat ctgatgcaag atagctgctc gaattcttct
     8701 cggtgaatct gctgcaatac cgatttgttc ggctagatta tctgcacgtt tgaacccgat
     8761 tccttctatg tcttcgacta gctggtacgg attttcttcg atgatatcca aagactcgtt
     8821 cttataggcc tggtagatac tgaaagctaa ctgactaccg aacccgtaac gattcagtcc
     8881 catgatcact tgatccatcc cgtggtttag ccgaatcgtc tcagcaagca tttctctttt
     8941 tggcttcgtc aaaccggaga tttgttttaa taccgaagga tcagcaatga ttttttcgat
     9001 agcatcttct cccagcaatt ctacaatttt ttctgctgtt ttcttcccga ttcctgggaa
     9061 tttttcgctg gaaagatacg ctacgatccc atttgcagtt gttggctttt cttgctcata
     9121 tctttcgagt ttaagctgcc ttccgtattt aggatgatcc actaattctc cataaaaacg
     9181 ataagtctca ttttcttgaa tatcgccgaa acttccggtg actacaatct ctttttcacg
     9241 gtaatcagct gtggtttcac tgatgtgtac caaaagcact ttgtaaaaat tactaggatt
     9301 ttgaaaaaaa atcgcggcaa ctgtaccaac gaaataaggc atttcttctg gctgcatcgg
     9361 aagccgcctc cttcttctat agtaaaggtt ctggtgctgt ttcagttcct aaaaaatctg
     9421 tttggttcca tactttcagt tcatatggca ataatctgca aggctcttca gtctctaaaa
     9481 tcgtcaaact actattgaac aatccaccca tttcacgcaa ctcacttagc tcttttcctg
     9541 tcatccattg aatggctgca gttaaagaag ctccatgtcc tacgaataaa agtgggccat
     9601 ctttatgttg ggcaaccgca tctgctacaa cagtttcgat acgtgtgatt gccgattcaa
     9661 tcgtttctcc gtgaaaagga gaaggatcat acagatctaa atgattacgc aaattcggca
     9721 gattatccgg atatttctgg tacatttcat cgatcgactg accttctaaa gtacccagcc
     9781 ctagttctct tagcttatct gtataaaaaa tctctaccgg acgagcaagc tctttgttga
     9841 taccttctgc tgtatcacgt gctcgctttg ctgtactgga ataaattgct ttaaaaggaa
     9901 catattttac ctttttccca aatgctttga tttcttcgta actttgtggc aaaagcggag
     9961 aatcgccatt gctcccttga aaacgtcttt cctgattcca ttgtgtcttc ccatgtcggg
    10021 taaaatatag ttccatacgc agcaaactcc tgtctttctt ttattttact ctataataaa
    10081 ctgtctaatc cagcttgtca ttttcatagt gatgcgtcaa ttctaaatta gggaatcctt
    10141 gctggcgaag tgcttcatac actatcattg cagctgtatt cgataaattc aatgagcgga
    10201 catgctcatc attcataggg atgcgtaaac acttttcttc gttttcacgc ataaatgttt
    10261 ctggcaaacc ggttgtttct tttccaaata aaaagaagtg ctcttctcca tcagcaaaat
    10321 tttcgtcact atatacttta tgggcaaatt ttgagatcaa atgtagttta cgattaccta
    10381 aaaatgttaa aaaagcttct aaattactgt ggtaagtaat atttacatca ttccaataat
    10441 ccaaccctgc ccgttttaga tgtttgtcat cagttgaaaa acctagtggc tcgattaaat
    10501 gaagcggagt attcgtggct gcacacgtac gggcaatatt tccagtgttt gcagggatta
    10561 atggttcaaa taaaacgata tgattcatca ggatcattcc tctcatattt atgttcgttt
    10621 ctattttctg acaatttgat ttttgcataa aaaaaaacgt atcaactcgg tgtcagtcac
    10681 tgcgagtcgt tacgttagtg aagctcttct cactaacttt tatcagaaca ggaacctgat
    10741 aaaaaccaat gaaaaaacaa cttgttgcta atataacacc ctcaactttt ttttgcaacc
    10801 tctactcatt aaaaactgct agaaaaacgt tttctcttag ttccttttaa taattctatg
    10861 tcaattgtaa tcttcttcaa aggattctta tataagtctg ctttgattcg ctcttctacc
    10921 tgccattcta aaggtgacat ggccaaaaga tctttttgat tttcctctgg tatctcaaat
    10981 tcataggtta cacgctgacg ttcagttaat ttcattgctt cagcaaactt ggctactaca
    11041 cgttcattgg aataactctg tttttcaggt tgattcggat aaaaagcctg acgtagttcc
    11101 tttaaataat tttcttgtgg caccaccttc aacacttctc catcttctga gagtacacgt
    11161 tggaattctt ggtaatgaga aggcgaaaag atatttaaaa ccgcgttgaa tgtttgatca
    11221 gcaaacggca aattggtcaa atcagctaca caccaaaatg cttcggcaga ttgttctgta
    11281 gctgcgtaga ctccttcttt tgaaatatca aatccaacag cattttgaat ctttttcaat
    11341 tttgaaagtt cattcaagaa gctaccttct ccgcagccaa catctaatag cgagacttct
    11401 tcaggtaaat gctgcgcaat agtctcaata acgggctgat acatgccaga ttggatcatt
    11461 ctacgccttg gaacgaacat tccttgatcg tattctgttt taaccgcatg ggataaaaaa
    11521 taaagtgttc cttttttgga aaggtcaaaa cggtgattat ttttgcatat caagccatta
    11581 tcagactttt ttacttcttc ttggcaaacc ggacagcgga acagctgatg attttctgcc
    11641 aaaaactggc gtcctcggtc aatttttttt aacatagttc cccctcattt ctgttttatc
    11701 ttaccgttag atgctcactt tggcaactgc taaaaatatg atacaatgcc tagaagaaag
    11761 tgaaagataa aggagaagat tagatgatca aagaattttg cgctgaaaac tacacatcta
    11821 ttcctctagc aattgctaga ggagccgatc ggatcgaatt gtgtgacaac ttagcggtcg
    11881 gtggcacaac cccgagtact ggtgtgatcg aagaaacgtt aagttatgct ggggaaaaag
    11941 atatccccgt aatgacgatt attcgtccta gagggggcga cttcgtctat aacgatatcg
    12001 aattgaaaat catgcatact gatttgattg aagcaaagaa attagggacg gatggcgtag
    12061 tatttggttg tcttactcct tcaggctggc tagacgaaga ggccttagaa ctattgatcg
    12121 aaacagcaga agggttgcag atcaccttcc atatggcttt tgacagtatt cctgaagatc
    12181 ggcaattcga agcaatcgat tggctggtag aacatggtgt tgaccgtatc ttgactcatg
    12241 gcggtcctgc tgacaaaact attgtagaaa atttcccacg gcttaaagaa ttgattgcct
    12301 atacagatgg ccgcttaatc attttgcctg gtggtggtgt cactgcagag aatgcagcac
    12361 atgtagctaa agaattgaac gtaagcgaag tacacggaac caaaatcgtg gatcttcagt
    12421 tataatctta taaacaaaaa aacatttgca acaggcataa tgcttattgc aaatgttttt
    12481 gtttttttac ataaaatagc ccataaataa agaagcaata ttgaaataaa tcagtacact
    12541 cgtcaaatcg ctcaaagtcg tgataaaggg accgcttgct actgctggat caaatcctag
    12601 acgatccatt agcatcggga ttaaactacc tgcaagattc gccactgtga ttgcaaatag
    12661 catagccatc cctatgacaa accccaagat aaaattatgt ttccaaaaac ctacgattag
    12721 aaaaatcgtg atccccgtaa cagctcctgt gacaacgccg gtcaagactt cagccaaaac
    12781 aagtcgaaca aatccatgat ctttctcatc agaaatcgca agtcgacgaa cagccacagc
    12841 tagcgactgg gttccagcat taccggcagt tcctgtaatc agcgaaatga agactgctaa
    12901 aatactcgct tcacttacca agtcttcata gtgactgatt aaagaagcgg tcgacatacc
    12961 taaaaacaac agagtgatca gccaaggcaa acgtcgagac gctgccttta ctggattttc
    13021 attaatttct tccacattga ccccggcaag tcctgaataa tcgctagcag cttcatcatc
    13081 aataacgtcg atgatatcat cgactgtgac gattcctaac aaatgatcat cataatcggt
    13141 aacaggaaga gctaagaagt cataatctct aaatgtttgt gccacatctt cttggtcgtc
    13201 gcctacatga actgaaagca ctcgttcgct catcagatca gaaatcattg cgtcgtcatc
    13261 attcacgatt aggtcgcgca gagaaataac ccctactagc tgaccttctt gattaacgac
    13321 atagatgtaa tagattgttt cagctacatc tgcttcgttc ttcagcacgt acatcgcaga
    13381 gcgaacagtt tgattggcta cgatcgaaac aaattcagtt gtcatgatcg cgccagccgt
    13441 ttcatcctcg taatggagaa gttccttgat ttcactggca tcgtctgccg acatcaaact
    13501 taaatattta gcaatttgct ttttatccag cgtattaagc aagtcaacag cattatctgt
    13561 atacatctca gaaagcatat cagctgcata gctaggacgc atttcatcta ggtattcttt
    13621 catatgttcg ttgtcttctt caatcacatc gaacatatcc gctaattctt taggcgacag
    13681 ataggaatag atcagctgcc tgttctcttc tgtaagagat tggtagaatt gcccctgctc
    13741 atagatatgc atctctaaaa aactgtttct gaatgcctga atattatttt cccttaaatc
    13801 ttgagtcaac tgggcaaatc tttcctctaa ttcttgattt tcatccaaac caatctcacc
    13861 tcgccttatt cttcaaaccg tctcacaact gcctccatgt ctgcggctaa aggctgcttg
    13921 aactccagca actcttctgt aaatggatgg taaaaacgca gatcataaca atgaagggct
    13981 tgtcttttta ttcccagatc cattcgcccg ccatacatat catcaccgag cagggcacag
    14041 ccaattgcgg aaaaatgaac tcttatttga tgtgtccttc ctgtatgcag ctggatatca
    14101 actaacgcga tttctgttag tcgcttctct atccagtact cagtctgtgc cgaacgtcct
    14161 tcatcagaga ccattcgctt caatagcgaa gaataatctc gggcgatcgg caaatcgata
    14221 tgtccatgtg ccgataaatc tgaaagcctt ccactgacta aggcctgata ttttttcaca
    14281 aacttctttt cacgaagttg catatctaat tttgcgtgcg caaatccatg ctttgcaaaa
    14341 agcatcaaac cagatgtatc ccgatctagt cgcgtcacca catggattac ttggttttcg
    14401 taaccttgtt ttttataata agcctttaca cgattagcca ttgtcccatt tggatggtat
    14461 tgggcaggaa tagacgaaac gcctgctggt ttatttacta ccagaacgtg ttcatcttca
    14521 tacacgatat cgatcggtgt ttcatccaaa agtacggttt catgttctcc ttcagcagga
    14581 atcacaatgg ttaccttatc atccttagct agagaaaaca agacattttc tacttgatca
    14641 ttaactttga tttgaccgcc ttgaaatttt attttcgcta acagaccctt tgagatccct
    14701 ttttctttta aaaaatattt tacttgctga gaatgatctt tctcataatc ccatgtaaac
    14761 tgcatatcaa tcctcactaa taaaggcatc tttcacacga tgccaaaaat gcatatgtcg
    14821 ataagaagca aaatggatcc gttcttctgc tattcgataa taaattgagc ggatatttgc
    14881 ttttgcgaca ttcaattgat caaccgttac aagataatct tctgtatttt ccaattttat
    14941 ttctagccat tcatcatggg caatcacgat cggagaaccc aaagtacgaa acactcgatt
    15001 attcagtgaa gcaatctctg ccaactgaaa ggcattgata ctaggatgga tcacagcacc
    15061 gccgacactt ttattatatg ctgtcgaacc agtaggcgta gaaatcgtca atccatctcc
    15121 tctaaaactt tcaaacagct cgtttttgat gtatacatcg gctaccatcg tacgattggc
    15181 ccgtttaatc gttgattcat tcagtgctaa aaaatgctgg tccggtgttt catccaaata
    15241 actgatccga acatccagca agggataact aacactttgt tcccggttcg ttcgtaagct
    15301 gtctactagt tcttccagct cgtaatcccg ccaatccgtg taaaacccta aatgacctgt
    15361 atgcacgccc aagaaacgca catcattcag acaatgactg tagtgatgga acgccgacaa
    15421 taatgtgccg tctccgccga ctgagatgac caattctggc tcatgatcat ctcgttgaat
    15481 ccctgcttgt tctaaaagtg cgttcaaacg ttctgtcact tctatagtct ttgcttcttt
    15541 attatgaacg atcgctactt tcatcccctg cctcctctct ttcgctttct ttcttcaaaa
    15601 gcgttcgata gtagacatca tctgattttc ctcttccatg ggagaataac cgctgtgctt
    15661 cttggatttc ttcacggata ctggacatct cttcatccaa ctgataggca gcttctgccg
    15721 cacgctgaag tcgttcactc atttcttctg gaaaaacgcc ttgatattta taattcagcg
    15781 aatgctcaat cgttgcccag aaattcatcg caagagtccg aatctggatt tccgccaaaa
    15841 ttttcttctc accgctgatc agctgtacag gatactcgat caccagatga taagaacggt
    15901 agccacttgc ttttttattt gtgatgtaat ctcgttcttg gagaactttc atgtcttttc
    15961 ttttacggat gatctcaaca acttgatgga tatcttctac aaactgacac atgatcctta
    16021 acccggcaat atcagacatt tcttcttcta aacgtcccat tggaatatgc cgtaattgtg
    16081 attttgttac aatactatcg actggcttga ctctcccagt gacaaattca atcgggacat
    16141 gtcgattttg ttcacggaac tgtttgcgga tcccccgcag tttcactttc aattctgata
    16201 cagtttgttc atatggtgct aaaaatgctt cccaatctcg ttccatagct gatacctcta
    16261 cttcattaac attcattgtt tattctacca tatatgcaaa gttttttcgt actcttgatt
    16321 tatgcattga ccaaaaaaag aaaattaggc aaaatagaca aaaaggagtc gatcaaatga
    16381 cacaaatgct tgaaatcgaa tataaatcta tgctgacaaa gcaagagtac gagatattca
    16441 tcgctcacta tcaattaaca gataaagatt tccgtgtaca gactaatatt tatttcgata
    16501 ccgttgatga acagctgaag aaacaaaatt gtggcctacg gatccgtttc gttggtcatc
    16561 aagctgaata tacattaaaa acacctgctg aaaaagggcg tctcgaaaca acggatacct
    16621 ttataacaga agaagcagaa gcatttatct tcgaaaaacg tctgcctcgt tcaggcgcag
    16681 tttttcaaaa actttctgat ttgaatatcg atcctgcttc attaatccaa accggaaagc
    16741 ttacaacaaa acgggctgaa ttccctattg aagaaggact tttagctatt gatgaaagct
    16801 ggggagacaa tctacacgat tttgaactgg aactagaggt aggggatgca tctgtgggaa
    16861 aaattgcttt tataaatttt ttaaaacgtt tttctttacc ttatcgtcct gctaagaaca
    16921 agatccaacg tatgcttgaa gctaaaaatt agaaaccttt cattttcaca aggcacttga
    16981 gttcattttt ttactttttt ctgttaagtt ataggatgtg aaagaatcta gtcactagtt
    17041 gtatagaatc tattttgggg gagattcata tgatcgaaat ctatttattt gttaatcctt
    17101 taggggaata ctgtttcgaa atggaacaac agttattaca atttatcgaa gaagagtacg
    17161 ggacaccatc aaaagaaaag atgcaatttc gctttcttcc tttggtcaat ttgcagacaa
    17221 ttggggatgt catgcaacaa aaaggaattt ctcagaacaa tcttgaggaa cgtaatcact
    17281 tattctcaat gacttattct gcagcattgg actgcaaagc ggcgcagttt caaggaaaga
    17341 aaaaaggccg ccgttttttg atcaaattgc aagaagcagt cggctgtaat gacataccat
    17401 attctcaaga acttgctgaa tccatatttg aagaaatcgg cggcgatttg aatatgttta
    17461 aagaagatcg tcagtctgac ttcgttaaag aagtattctt ttctgatcaa aaaattgctc
    17521 gggaaatggg catcacaaaa cacccttctg cagtcgttta caattatgcc tgcgaccgtg
    17581 attttggtgt tttagtagaa gtaaaaggta caagtagcct ttggagaatc acagagctgt
    17641 gtaaaacaac agataactca tatcaagttt ttaatggtga acatttacat acaaatgatt
    17701 ctcagttcca ttcaagaact agccatttac acttgctttc taattaaaaa aatacgtcga
    17761 ctcccttaca agagagccga cgtatttttt tcgtttctat tcgagaaaat caaaaataga
    17821 aagccttata aacgatcgat caattcttct aattcattta gacgttgttc aaacatcgac
    17881 attgcatctt caatatatgc agcctgtgtc atatcaactc ctgctttttt cattacttcc
    17941 acaggataat cgctgttacc tgcttttagg taagccaagt agttctctag tgcctctggt
    18001 tcctggttta gtattttctt cgccagtgct gaagcagcag aaaagccagt cgagtattgg
    18061 aaaacatagt aattataata aaaatgcggt atccgtgacc attcgaattt aatttctggg
    18121 tcttcttcga ctgctggacc ataatatttt gcattcaatt taccataact atcacttagg
    18181 tattcactag tcaatggcac acctttttca tcttccgtat gcatgaaatg ctcgaattca
    18241 gcgaattgtg tctggcggaa aactgttcct ttaaacccat ccaagtaatg gttgagtaca
    18301 taagcccgta cacgagggtc tttttctgtt tccaataaat actccgttag gatattttca
    18361 ttcgttgtcg aagcaatttc tgctaaaaag atggagtagt cgccgtacac ataaggctgg
    18421 ttcgaacgag tgaaataact atgaacacta tgtcccattt cgtggacaag cgtaaatagc
    18481 tgatccagcg tatcatgcca attcaataaa atatatggat ttgtgtcata gcttcccgaa
    18541 gaataagcat cgcttcgttt ccctttattt tcgacaacat cgatccaacg ttcagagaat
    18601 gctttttcta cgatggccat gtattcttca cccattggtt tcagtgcttc taaagctttt
    18661 tcttttgctt cttcgtacgt aaaggtaatt ggagcttccc ctaagaccgg tgtataaaga
    18721 tcatacatgt gcagtttttc cacttctaat aaacgtttcc gtaattccat gtatcgatgt
    18781 aacaaaggca aatgcttgtt taccacgtct accaaagtat cgtatacact ttcaggaata
    18841 tgattattgc tcaaagacgc ttctctggca gagctgtaat tacggacttt cgctttaaaa
    18901 ttatgtcctt ttatatgtgt gcctaaagta gaagcaaatg tatttctaaa ttgttcgtaa
    18961 acactgtaca atcccttaaa tgctgcttcg cgcacccttc gatccgtgct ttctagcaac
    19021 tgaccataca cgccatgaga taattggact atttcaccat tttctccttc aatcgttgga
    19081 aaaactagat ctgcattatt caaaacagca aatgtatcac ttgaagcatc aaagatttca
    19141 cctgctccag caagaagaga ttcctgctca gcagataaga catgggctcg attatctact
    19201 atttgctgga tataatggcg atagacttcc aattttggtt cttctttgaa atattgccaa
    19261 atctggtcat ctgacaattg caatatttct ggttcaaacc aggaaacggc ttcactaact
    19321 ttcgaaaaca gactgcttgc tcttgcataa agcgcttggt aatctgtatt tccagtgtct
    19381 tgatcgtttt taaggtgcgc atatacataa atgacttcag tttggcgata aaccctcaat
    19441 acgaattcaa tcgcatttaa aaattgagaa gcgccttgat caagtgttcc tttgtgtttt
    19501 tcagattgtt ttaactcttc tgataattcc aaatatttct catcaaactc ttggtcgctt
    19561 gaaaagatct tggtcaagtc ccaagttaaa ttttcaggca attcttctcg ttttggcaac
    19621 tgctttactt ccatgaaatc cactcctttt cttcccttag ctctatctat caaaatagat
    19681 catagtctaa catccacatg tcacagcatc taacttttct actcattcat gtgtctgctt
    19741 ccatcaattt tagcataact aaatcttgtt ttacatagaa aaccgattcc tagcctattt
    19801 ttatacttac tattttttca aagaagacaa gtgtatgcat tcgttaaaaa actgctgata
    19861 gaccatctct tcatcaatca taggaaaaag ccattccctt ttatgttctt ttatttggca
    19921 aagccatgag ttgaaatcag gaactttctg gttttccaag gcttcttcgt acaacattcg
    19981 ataaagaaaa acctgttctt gtaaataaaa gaaaaaccga cttttttgat agatccacga
    20041 tgatagatgc aaaagatgtt tatgacgcaa gtagcattgt tcttgtatgg atactgtatt
    20101 cttttgcttg tgaataagtt ggcgtgtcag ccatttcttc ccatcttcac tcactttttc
    20161 tatttttttc atttggttca ttttaatttc gttactagtg aatatttctt taaggtccct
    20221 actagaaaaa gtccagcagc tactgcaaaa ggaaatatgc cctgatacag tctctgtaat
    20281 atgatgatac aaataaagct tttgtttctt gagatcagct ttccagcaat gcactcctct
    20341 ttttctatta tagtagcagc aacttttttc tatcaatgag aattgcgatt gtccaagaaa
    20401 agaattacca agtatccacc atacttggta actgttattc aaataatttt gggttctttc
    20461 aataaatctc tggtgagaca gtctagaaca ttggatttct attgctagat tcgccaacaa
    20521 aatatccggc ctttgccgca acctcggcaa ataggcttcc aaaaatactg gttctactga
    20581 ctgtcccagc caatccatga agcattcctt taactgtaag tgctcttttg attctctttc
    20641 actaaagacc gaacagttat ctgatttttg atgggcaaaa tgagcacatt ttttctttcc
    20701 ctttttcaaa atcactcttt ttcgacagcc acgacaataa tatttctttc ctttttctgc
    20761 atgtttagca aaacagcact tattatattc attcattgca agcagcattt ttctccctct
    20821 gaacttattt acgtctaaga atttatttac acgaaaaaag agggcgtgaa aaagctattc
    20881 tgcatcaagt aataagaaca gctaaacaaa aatagttccc aatatttttc gtttggttgg
    20941 gcttgttacc gcagatgcaa gcttttgaac acatttatac gaaaaaaaga ctgcgacaca
    21001 atttttgtca cagtctctta ctataatgct gatttataca aaataaaatt tcgttcgctc
    21061 gatagcatta cgcgccatca gacattgtcc atattcattc aatgtttctg gtgtacgatc
    21121 gctcttttca gcaaactcca aaattcgagc aatctgattc tctacatccg cttggttgag
    21181 attttccatc cagaagtgaa cgactaggta atagcgctct tcgaataaat acaaatcagt
    21241 ccaagcagac tctagttcga catctgttgc aagttggatc acttgttcaa aatcttcaaa
    21301 agcaaaagtt gcttgtcttt cctgttcttc tagggcgctt ccagataatt cttcctccgg
    21361 atcgctgcca ataatctgct gacgaagaaa gtcactcaca tcttctgaat caacagtaga
    21421 atcttctgat tgagaaattt cttcatccgg aagattttta ctgataaaca gttctaatcc
    21481 gtctcctttt ggcaaaactt ggaaagtgac agcttcgctt cctcggaact cctcttcgat
    21541 atcaacttct tccaaaatac tataaaagaa attttcgatt tctttgtgat tgccaagtaa
    21601 atccaaaaat gaaacgcccc gttcctctaa atcttcatga ccaattagta cacggatcgt
    21661 attttcatta atatgttcca tttccatttt gctacacctc actttgccac aatgtttaat
    21721 atagattcat tgtagcgaaa tcagcttaaa tgtaaagaaa aaaaatctcg ctgttaagcg
    21781 aatttaataa aaccagcgga tttttcaacc tttcaagcta tcttatttaa ctataacatt
    21841 tttggcagac gaatactata tagccgactt ttcagctaat tttccctctc tatttttcgt
    21901 gcaatcatca tcttctacta cctttttata catctaatca agaatacttt ttgtaaaaac
    21961 aaaaaaactt ggaaaaacta tctttgtaat agt
//
LOCUS       DAZUJR010000049        21727 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.049, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000049 DAZUJR010000000
VERSION     DAZUJR010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21727)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21727)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21727
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.049"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(15..425)
                     /locus_tag="ACG804_001748"
     CDS             complement(15..425)
                     /locus_tag="ACG804_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4832677.1"
                     /translation="MLLDRIKILLKERSMTLAELERKLNFGNGSMSRWNKSTPSGDKI
                     QKVADYFNVSTDYLLGRTDKRHYYDLTEKDKQDIALQAEKLLEGLNSDAETNYYGEPL
                     DDEDKEKLYDAIQLALALTKVKAKKKFTPKKYRQ"
     gene            700..912
                     /locus_tag="ACG804_001749"
     CDS             700..912
                     /locus_tag="ACG804_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiprotein-bridging factor 1 family protein"
                     /protein_id="HFS4832678.1"
                     /translation="MTLKQQVLIALVKKGWSQRELARRMGISITYLRDIFIEKRKPKE
                     RLKQIEELLDIKLEVDSNDQPSEQEA"
     gene            915..1127
                     /locus_tag="ACG804_001750"
     CDS             915..1127
                     /locus_tag="ACG804_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832679.1"
                     /translation="MVQRLSKAEFKEKYKYSESTYQRRMKEFKKSRFSEGYNAVTSKE
                     ITIDVDLYEQFRTWRSKNRFRVRAVC"
     gene            1267..1422
                     /locus_tag="ACG804_001751"
     CDS             1267..1422
                     /locus_tag="ACG804_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832680.1"
                     /translation="MKEESKIGILNENNYTRLIIETEEGKKVAEVTLTDATPADGYRI
                     RLTPKYD"
     gene            complement(1419..1643)
                     /locus_tag="ACG804_001752"
     CDS             complement(1419..1643)
                     /locus_tag="ACG804_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HFS4832681.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            1721..1909
                     /locus_tag="ACG804_001753"
     CDS             1721..1909
                     /locus_tag="ACG804_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832682.1"
                     /translation="MAYTLQQEHQILGLIKQRRKQLQDDRAALRKADELSDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            2048..2176
                     /locus_tag="ACG804_001754"
     CDS             2048..2176
                     /locus_tag="ACG804_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832683.1"
                     /translation="MAREEALKIGKVIADNRWGNSRPIILSKQHIEKQKAWQQIKK"
     gene            2235..2570
                     /locus_tag="ACG804_001755"
     CDS             2235..2570
                     /locus_tag="ACG804_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832684.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            2803..3744
                     /locus_tag="ACG804_001756"
     CDS             2803..3744
                     /locus_tag="ACG804_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lambda-exonuclease family protein"
                     /protein_id="HFS4832685.1"
                     /translation="MSKSTLEMSHQEWLEDRKKGIGGSDVGTILGLNKWKSPYQLWLE
                     KTGQVVLEESGSEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPIIDGSQATADFLKEKYADVEDVQTT
                     LPIHFDELVEQKNELKRTKKEIESAIRQVDNEIISELGKREASIGITQKNIISWKFVR
                     TRRMNSKKLAEKYPDVANDEEIYNVTESRRLTEREIK"
     gene            3746..4636
                     /locus_tag="ACG804_001757"
     CDS             3746..4636
                     /locus_tag="ACG804_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HFS4832686.1"
                     /translation="MATNESLKNQLAAKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            4679..5479
                     /locus_tag="ACG804_001758"
     CDS             4679..5479
                     /locus_tag="ACG804_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HFS4832687.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWNLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADDIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            5494..6345
                     /locus_tag="ACG804_001759"
     CDS             5494..6345
                     /locus_tag="ACG804_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFS4832688.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGAIA"
     gene            6546..7007
                     /locus_tag="ACG804_001760"
     CDS             6546..7007
                     /locus_tag="ACG804_001760"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFS4832689.1"
                     /translation="MPKILDACCGSRLFWFDKNNSDVTFMDCRQQYEELSTGHVINVD
                     PDVVADFRDMPFEDDVFDMVVFDPPHLRHVGENSWLAKKYGKLDELWPEDIRQGFAEC
                     MRVLRPSGTLIFKWNEEQIPLSDVLEAIGEQPLFGNKRSKTHWLVFMKKFS"
     gene            7033..7485
                     /locus_tag="ACG804_001761"
     CDS             7033..7485
                     /locus_tag="ACG804_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832690.1"
                     /translation="MKIVLNKCFGGFGLSHEAKMEIFKRKNIEVFPYINNFSYDSDDE
                     YTRYTGQKLGSMDFIYYFKKDPKIDKVTGIYSEIDRLYGIADDSSFSSDSNRGDKDLV
                     AVVEKLGSEASGPYASLKVVDIPDGAEWEISDYDGVETAHYGFQTGSI"
     gene            7591..7785
                     /locus_tag="ACG804_001762"
     CDS             7591..7785
                     /locus_tag="ACG804_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832691.1"
                     /translation="MDASEVVNKINSLKEVFGDVEVVINAQGYDNEFFKQITDISIQQ
                     GMEDEDGNFIDEVAILVTCE"
     gene            7816..8109
                     /locus_tag="ACG804_001763"
     CDS             7816..8109
                     /locus_tag="ACG804_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832692.1"
                     /translation="MKLKDGFYSSGHGIGGLMLDMPTKNPKTRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVVRLVDMEVIKS"
     gene            8040..8579
                     /locus_tag="ACG804_001764"
     CDS             8040..8579
                     /locus_tag="ACG804_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family phage packaging/lysis
                     transcriptional regulator"
                     /protein_id="HFS4832693.1"
                     /translation="MVSEKQREFSSGEIGGHGSYKILILLFYNYPTTMSVIPQLEGEE
                     AIVNILENIDIKQTRKNARRLLKRYRNLERLVGPVKIDFSVMTVTKNLKFTIDSQNEE
                     IIEAISTRDSVIEALTRLSRIHFQVLYYSYCFPNKMSMYQIGEKLGYSDRTIERMKAV
                     ALVEFAEAYKSGELISRTK"
     gene            8654..9121
                     /locus_tag="ACG804_001765"
     CDS             8654..9121
                     /locus_tag="ACG804_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HFS4832694.1"
                     /translation="MVLFDVKKYETPSAKDVDMERTKHNVAVFLSAYLSARCRVGQHR
                     EPKVTASYSLVPPSTADHIFEAERMLIDKEEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            9868..10098
                     /locus_tag="ACG804_001766"
     CDS             9868..10098
                     /locus_tag="ACG804_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832695.1"
                     /translation="MRNYWYVSLTNEYPRTIDDCSVRVVRSVQIKGKYSIVEMGREAE
                     PCEIDACKLVYCGHGFYDEPNIQNNINKNLRD"
     gene            10257..11090
                     /gene="terS"
                     /locus_tag="ACG804_001767"
     CDS             10257..11090
                     /gene="terS"
                     /locus_tag="ACG804_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit"
                     /protein_id="HFS4832696.1"
                     /translation="MARQRDPRRDEAKRIWLESNGEKQLKEIASELNVSDSQVRKWKS
                     QDKWSAELISNVTNGKSNVTNQGGAPIGNQNAKGNKGNSRASPPVGNKNALKTGEYET
                     IFFDTLTDNEKDIYSSLNDDPSFALSEEIRLLKIRQLRMMKRIQQAEAGLNDEEVERL
                     QQLRKIKTPIEKNGKKLEIKREVMQDVQISRKKHRKIDDILSIEDSLTRISNQLAKAI
                     KQMNELYMNEYRTDLIKAQTDKIQAETNEIGGNNSGEEIEEWKQAVLNAANKRAVKEN
                     E"
     gene            11083..12498
                     /locus_tag="ACG804_001768"
     CDS             11083..12498
                     /locus_tag="ACG804_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HFS4832697.1"
                     /translation="MNNEFIPFADIGSAIDYYYDKPVAFCQDILHLNPDEWQENVLND
                     LAEFSKVSVRSGQGVGKTALEAGAILWFLTCRPYAKVIATAPTMKQLYDVLWAEVAKW
                     LNDSLIKNLLKWTKTKIYMVGDSERWFATARTATKPESMQGFHEDHMLIVVDEASGVS
                     DPIMEAILGTLSGFDNKLLMCGNPNNIEGVFYDSHNSDRDKYRVHKVSSYDSKRTNKD
                     NIEMILKKYGKESDVARVRIFGEFPKGALDSFISLETVELATEKQISDSLVNKTKVAH
                     IGVDVARYGDDSTILFPRIATRALEYEKYSKRSTMETTGYVINMAKNLMSQYPSIDKV
                     MIKVDDTGVGGGVTDRLEELIEDKHYPFEVFGVNNGSTSEDDFYDNLGTQLWGNIKEM
                     LEENMTANLNGEQPVIELPSDSSLIKELSTRKFKMTSRSRIRLESKDDMKKRNIGSPD
                     IADALALAFYEPPSHYQFIQF"
     gene            12510..14039
                     /locus_tag="ACG804_001769"
     CDS             12510..14039
                     /locus_tag="ACG804_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFS4832698.1"
                     /translation="MISTVLSLERYKKLRVKYATQIEDGMFDPNGFIEDMKPFFADRE
                     RKYLAYTSEKNEIDNRPKPNTDIVKVNNKLHAGMYSIVVDQAVNHFTGIPIKWDYDVS
                     EQKRTLIQRLKDKFLKNDIELPTVPEAFNKLTSNLDSMRFAMLDSETATFQGACGVAF
                     RLLEPVEEDDGWKLRASNIEPWRAERYGNAGIYIKEKYDSYQKKFFQEMKVMTRNKIL
                     TYACYGDLNFVTSGTFKKIDETDNPLGTITLAEFKNNTNRYCDFEVAEEIGDAIDRAL
                     SDQQNEIEQFKLAYMLVTGTTMSKGTAKEMMNQLGIINLKAPTAKAEYVTKNLAKDFN
                     EYHMDLLKKQFYTICKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAETIAAFLKFHDKVEIEPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMMELESGSAYPDSEYNFGGGGNSDDRNEVLDQTSRTGGSSKAQTRKSD
                     T"
     gene            13957..15009
                     /locus_tag="ACG804_001770"
     CDS             13957..15009
                     /locus_tag="ACG804_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HFS4832699.1"
                     /translation="MTIETKYWTKRRELEDQARLKQENQTLKKLTSVFPEALKEIQAK
                     LLSQADLHNITYPEMMEFYSTSNQKKYREYVEKNYKSLKMYDAKYKEFIDEFFPPFDY
                     AKVNRLLQIRSDVFKILAEYAMDADVNQYFSDRLEEILQRTYSSNANVFVQLLNVDIP
                     NYLPENEIKHYLNYPWSGKTFSRRLWGNISSLEQKLSNAIVKSVASGEGVIHALNTMR
                     LDSEICDMFKLEESKYNKAIENLVRTEYAKFAQDGIEKSYLETGIEEYNVLTAKDERV
                     CRICGGKASKNPYKLKDAVIGENRAPFHSRCRCTDVPNLPKLGKDIDEEYDRLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            15011..15328
                     /locus_tag="ACG804_001771"
     CDS             15011..15328
                     /locus_tag="ACG804_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832700.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYEKMGCIVVRTDYKEGK
                     SSN"
     gene            15455..16078
                     /locus_tag="ACG804_001772"
     CDS             15455..16078
                     /locus_tag="ACG804_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HFS4832701.1"
                     /translation="MSMKHKSLMPMNLQYFAEGDDQKFSFDDFKSFVESNEEAQKFIQ
                     SQSQSVADKQLEAWKQNNLDKIKQDTIKEYEESKKNKSPEQIQLEKLQAEFEAEKALR
                     VTSDNKAFVAEQIAGLELDGELKESISQFMLNNLVSSDTDFTKNAVEGFTSVLNAINE
                     KHADALKELQMKSAFGGTQQSNNQVQQNNETLTNPEEQLGQILQQFN"
     gene            16093..16983
                     /locus_tag="ACG804_001773"
     CDS             16093..16983
                     /locus_tag="ACG804_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 family protein"
                     /protein_id="HFS4832702.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            17006..17221
                     /locus_tag="ACG804_001774"
     CDS             17006..17221
                     /locus_tag="ACG804_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832703.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            17233..17574
                     /locus_tag="ACG804_001775"
     CDS             17233..17574
                     /locus_tag="ACG804_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832704.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            17574..17945
                     /locus_tag="ACG804_001776"
     CDS             17574..17945
                     /locus_tag="ACG804_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832705.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            17938..18333
                     /locus_tag="ACG804_001777"
     CDS             17938..18333
                     /locus_tag="ACG804_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HFS4832706.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGEVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            18335..18712
                     /locus_tag="ACG804_001778"
     CDS             18335..18712
                     /locus_tag="ACG804_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6838 family protein"
                     /protein_id="HFS4832707.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNNPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            18713..19321
                     /locus_tag="ACG804_001779"
     CDS             18713..19321
                     /locus_tag="ACG804_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="major tail protein"
                     /protein_id="HFS4832708.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            19321..19662
                     /locus_tag="ACG804_001780"
     CDS             19321..19662
                     /locus_tag="ACG804_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832709.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGTVVEDAAGVMEE
                     MQTATDKQSVKKALSRAYSFIADTLFEGQFTGEDYCKGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            19904..>21727
                     /locus_tag="ACG804_001781"
     CDS             19904..>21727
                     /locus_tag="ACG804_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HFS4832710.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNSGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVGSSMESFLKVIAANIPTAVSFLSNLFNEIQKFGSALKFMMPFLVPA
                     ATAFGAFMFQLKGIPAIIKSFNNFKNAIIGVGNSLKIMGAIAAANPFVLIIGAVVGAI
                     AVFGYFMATNEELRNKVISIWNDVKDSVIGVLKNIKDWGIDTWNSAKEMASNAVEGVK
                     DAWSGTKEWFSNTWKGIKDGATGLFDKTVETSRNAVDSVKNAWSNMKKWFSDTWQSIK
                     DSAREKWNGIKGSIMSVAGPLITGIKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LAPVLFITSMISGGWEETKNNMIAVWNNIKESAINIWESIKN"
BASE COUNT         7825 a         3194 c         4516 g         6192 t
ORIGIN      
        1 ataccaaagc ccacctattg acgatatttt ttaggagtga attttttctt tgctttaact
       61 ttggttaagg caagtgcaag ttgaatggca tcgtataatt tttccttatc ttcatcgtct
      121 aaaggttcac cataataatt tgtttcagca tctgaattca agccttcaag taatttttca
      181 gcttgtaaag caatatcttg tttatctttt tctgttaaat cataataatg gcgtttatca
      241 gtacgtccta aaagataatc agttgataca ttaaagtaat ctgcaacttt ttgtatttta
      301 tctccagatg gagtactttt attccatcta gacatgcttc catttccgaa atttaacttt
      361 ctttcaagtt ctgccaacgt cattgaacgt tcttttaata agatttttat acggtctaat
      421 agcataggat atgcattcct ttcaaaatac cgacaaaaaa agtatttttc tgcaaattat
      481 ctatttacaa atagagaatt tgcagttata ctagttttgt aagcaagata tttacggcat
      541 acaaagacta aaagcaataa actaatagtc tccccagaca tcagtaagct cgctttttgt
      601 gcgctgtatt ttgtatgctt acataatagc atatttgcag tttttgtcaa acttattaga
      661 caaaaatatt agaaaatatt cgataagggg gtatgaagca tgactttaaa acagcaagta
      721 ttaattgctt tagtaaagaa aggttggagt caaagagagt tagctcgacg aatgggtata
      781 tcaattactt atttacgaga tatcttcatc gaaaaaagaa aacctaagga acgtttaaaa
      841 caaatcgaag aacttttgga tatcaagtta gaagtagatt ctaatgatca gccatcagaa
      901 caggaggcgt aaaaatggta caacgtttga gcaaagcgga gtttaaagag aaatataagt
      961 attctgaaag tacttatcaa agaagaatga aggaatttaa aaaatcacgt tttagtgagg
     1021 ggtataacgc agttacttcc aaagaaataa caattgatgt cgatttatat gaacagttta
     1081 gaacatggcg ttctaaaaat cgatttagag ttagagctgt ttgttaatag ctaaaaaatc
     1141 taaattcacc acttctgaaa agaggagttg ctgctctcct ttcaagtttg ccaaagtcca
     1201 cgttttttca ttttggcaac tcctcttctt ggaggtggtg acggcgagag acgaaggagg
     1261 gatgacatga aggaagaatc aaaaataggg attttgaatg agaacaatta cacaagatta
     1321 attattgaaa cagaagaagg gaaaaaagta gcagaagtta cattgaccga tgcaactcct
     1381 gctgacggtt atcgtattcg attaactcct aaatatgatt aaccttttgg tgggtgtgga
     1441 tcgtttccgt gactatcacg gctttgaatt tttccatctc tgccatgaat aaatagctca
     1501 gatccttgat ttttagaaat ctctctagcg atttttactg cttctgattt tgtattagta
     1561 tgtgcagtcg ctttagaatt tccagcacct ttgacattcc aaccaccatt ggaattaggt
     1621 acaacatgtt gattttttcc catagttttc acctccattt ctatagaaat attttatcaa
     1681 atagaaatgg agaaattcaa taaacgaaag gagaagtgat atggcatata ccttgcaaca
     1741 agaacatcaa attctcggtt tgattaaaca acgcaggaaa caattacaag atgaccgtgc
     1801 agcgcttaga aaagccgatg agctatcaga taggcaagct gaactaattg cttctgaact
     1861 tgaggatttg agaatgctag aaataaaaaa tagggagatt agattatgaa gaagacagac
     1921 acacttttta taggattcat tttggggtta ttagtgattg tagcgcacca aagtattatc
     1981 gggggaagct tgttcgcagc attgatggtt ttaatcaatc tgcttgattc aaaagaaagg
     2041 agcaactatg gcacgagaag aagcgctaaa aatcggtaaa gtgattgctg ataatcggtg
     2101 gggaaatagc cgccctatta ttttaagcaa gcaacatatc gaaaagcaaa aagcatggca
     2161 acaaataaaa aagtgactct gccagccagc aaagagtcac atacaaattt ataaaactag
     2221 gagaattata tcacatgaat aagaaaattg aaaatcttat cgaagaattg aaacgtgaat
     2281 gccaaaagca aggtgtttct attatttgta cagcccaaaa agaaggggaa cttaaaagtc
     2341 tcgtttatgg tgagacaaca gaaattttac tttgtcttgc tatgcaagaa gaacatttag
     2401 atgaaaatct cccattgtca gcacatatta tgcgtagaat tgctgtggat gcttacgaac
     2461 aagcgaaaaa tgaagaagaa aatcaacctt caaatcatac ttttgttatt aataacaagg
     2521 aagatttagc tgatgtgatg actcgtattc tcaaggggga atttcaatga tgaatgaaaa
     2581 aacaattgat ctactcatta ttttattttt cacgttagtg attgtagcga aaagttatgt
     2641 aatctttggc ttgttattcg caattaccat gcttgtgctt tgcgtgttag caagcagaaa
     2701 agaggttaaa catgaacgag ttagcaaatc ttgacaacta tttaactgat cctgattatg
     2761 ctaaaccacc atatgaagca ccaattgatg aggaggatga agatgagtaa atctacctta
     2821 gaaatgagcc atcaagaatg gcttgaagac cgtaagaaag gcatcggagg ttcggatgtt
     2881 ggaacaattt taggattgaa taaatggaaa tctccttatc aactatggct agaaaaaaca
     2941 ggacaagtag tacttgaaga atcaggaagt gagcccgctt attggggtaa tgttttagaa
     3001 gaagtggttg ctaaagagtt tcaggaacgt acaggcaaaa aagtacgcag aagaaaccaa
     3061 gtatttgaac atccattaca tccattttta agagcaaata ttgatcggga agtagtggga
     3121 gaaaatgcca ttctggaatg caaaacagcc aatcaatttc tcggtaaaga atgggaaggc
     3181 gaagaggtac cgcttagcta tctctgtcaa gttcaacatt acatgaacgt tctaaacaaa
     3241 gactattgtt acatcgctgt cttaatcggt ggtcaaaaat ttatctggaa gcggattgaa
     3301 cgagatcaag agctgatcga tacaatcact gaacaattag tagagttttg ggaaacaaac
     3361 gttcttggag gtatcgagcc aattattgat ggtagtcaag cgacagctga tttcttgaaa
     3421 gagaagtatg cagatgttga agacgttcaa acgacgttac caattcattt cgatgaacta
     3481 gttgaacaga aaaacgaact caaacggact aagaaagaaa ttgaatcagc tatccgtcaa
     3541 gtagacaacg agattatcag cgagctaggt aaacgtgaag ccagtatcgg tatcactcaa
     3601 aaaaacatca tcagttggaa atttgtccgt acgagacgta tgaactcgaa gaaactagca
     3661 gagaaatatc cagatgtcgc aaatgatgaa gagatttata acgttactga atcaagaagg
     3721 ctaaccgaaa gggagatcaa ataatatggc aacaaatgaa tcgttaaaaa atcaattggc
     3781 agcaaagcca cagaaacaag ttgcaccagg tcaattagga cttaaagctt tgatgaatac
     3841 accaacaatg agaaagaagt tcgaagaggt gcttcatgac aatgctaatg cttttatgtc
     3901 gaatgttatg actcttgtat ctaatgacag ttatcttgca gatagtgaac cgatgtctat
     3961 catgagtggt gcgttaactg ctgcaacatt aaatcttggg ctagataaga atttaggtta
     4021 tgcatattta gttccattca atagtaaaaa caagcaaaca ggaaaatggg aaaagaaagc
     4081 tcaattcatg cttggctata aaggatatat ccaattagcc caacgatcag gtaaatacaa
     4141 agcattaaat gtgatcgaag tttacgaagg agaactaaaa agctggaacc gactgacaga
     4201 agagtttgag tttgatccaa atggtagaac gtctgatgaa gtcattggat atgttggcta
     4261 tttcgagtta ctgaatggat tcaaaaaaac tgtctattgg accaaacaag aaatcgaagc
     4321 tcatcggatt gctaacaata aagatcgcga taagacaaag ttaagtggtg tgtgggcatc
     4381 tgattacaat gcaatggcac gaaaaactgt tttgagaaat cttctttcta aatggggaat
     4441 cttgtccatc gaaatgcaag aagccaccac atcggatgag agagtccaaa gggttcaaga
     4501 agacggcagc attattgctg aaacagaagt tgaagaagat attcctgaaa gaaaagaagc
     4561 agaggttata tctgaagaaa atgaagatgt acaaactgga ttatttgatg catctaatcc
     4621 gccgttaaac aaataatgag ggagctttct cccttgcttt tctagaggag aaatacgaat
     4681 gaacacagga tatgtcaaat tacatcgaaa agtgatgaat tcattcgttt ggaccaatcc
     4741 ttatatgtat aaattatgga acttgtgttt gatgaaagcg agtcatgaga atcgcaagat
     4801 actttttaat ggaaaagaga tacaagtgaa cagcggagaa ttcgtcacag ggcgcgatgc
     4861 tatcacatct gagatgaacg aaggcgtgaa acgtgaacat caagtgaaca gcggttctgt
     4921 atggagatgg ctaaaacaat ttgaaaaaaa cggaatgttg aacatcaaat caactacgaa
     4981 atacagcgtt atatcaataa aaaactggtc tttgtaccaa agcagtgaac aacaaatgaa
     5041 catcaaacgc acaacaagtg aacaacaagt gcacacaaac aagaatgaaa agaattataa
     5101 gaatgaaaag aataataaaa catcatcgtc gcaaccacgc aaaaagcgtg tttacgacac
     5161 cgactcagtt tactacattc tcgcggagga gttattcaaa cagatttgtc agaatcagga
     5221 aatcaaaaag ccgaatctgc aaagttgggc agatgacatt cggaaaatga tcgagatcga
     5281 caagcggacc gaaaaccagg tacggggaat gattgaatgg agtcagcaca atgtgttttg
     5341 ggcatcgaat attttatctg ctaaaaaatt gcgagaaaaa tacgacacaa tggcagcgca
     5401 agcaaatcgt gattataaaa caaaacaaac taaaacgctt gaatacgaga aatttagcac
     5461 agatgagttg cctatttgag aggaggcgta ggcatggaaa ctgttgggga aatcatggaa
     5521 aagctgatac agaaagtgct tgtccaacgt ggcgaatgtc ctgaatgcgg acagcctttg
     5581 tatggatggc gtacgaagaa ccctgatggc tcagaacgtt gtaagccaac ctgtatgcaa
     5641 tgtgggtata aagcattgcg agttcaggaa gacttacaaa cagaacgaat ttacaacgag
     5701 agcctgaaag caagagcaat caattttttc aaaggtggtt ctgttgtgcc taatcaagcg
     5761 ttgtttgatt gcacattgca gaattatcaa attgtcgatc aagaaacaag acaagcggtt
     5821 gaagtaacca aacgctttgt taattcagtc ttgttaggaa atccaagtca ccttgtttta
     5881 actggaaaac aaggaacagg taaaagtcac ctagcgatgg cagcggcttg ggaagtcttg
     5941 aagcgatcaa actacgataa aaaaatctta tttatcgggt tacaggaaat gctggatcaa
     6001 atcaaatttt cgtacaacaa tcctgaactc agaaaaacga ttgagggatc gttgattgca
     6061 gatatcaaaa cagcggattt agtcatcatt gatgatatcg gttcagaact aggaaaagat
     6121 gcatcagata gtcgagcgtt tggcataaac acgctaaatt cgttcttgga tgcacgacag
     6181 aacctagcaa cgattatcac aacgaacttg cttggtgaag aactgaaaaa agcttacggt
     6241 acgagaacaa tatcaagaat gtttgtcaac tctgatggat ttacgatggt attttctcaa
     6301 acagcagaca agcgcataaa accagtcaaa ggagcgatcg catgaatttg actaaacaag
     6361 aaaaaagaat ctgtcgtcag ataatgttgc aaattatagg tgatcgtgac atggacgaat
     6421 tatctcaaca agagagtcga atggttcgga agataagtaa gctaattatt tatcgggata
     6481 cagaaagatt tctcactgtt ttaggtaacg tctacgagaa tccagagtta ttggaggtag
     6541 agtaattgcc aaaaatatta gatgcatgtt gcggtagtag attgttctgg tttgataaga
     6601 acaattctga cgtaacattt atggattgtc gtcagcagta tgaagaatta tcaacaggtc
     6661 atgtgatcaa tgttgatcca gatgtggtcg cagactttcg cgatatgcct tttgaagatg
     6721 atgtgttcga tatggttgta tttgacccgc cacacttaag acatgtcggc gaaaactcat
     6781 ggcttgccaa aaaatatgga aaattagacg aactttggcc agaagacatc aggcaaggtt
     6841 ttgcagagtg tatgcgagtt ttacgacctt caggaacatt aatttttaag tggaacgagg
     6901 aacagatacc actttctgat gtgttagagg ctattggaga acagccattg tttggtaata
     6961 aacgaagcaa aacacattgg cttgtgttta tgaaaaaatt cagctaacgg aggaaacaaa
     7021 ggaggaaaag taatgaagat tgtattaaat aaatgttttg gtggctttgg gttgagccat
     7081 gaagcaaaaa tggaaatttt taaaagaaaa aatattgaag tattcccata catcaataac
     7141 tttagctatg actcagatga tgaatacacg agatacacag gccaaaagct aggttcgatg
     7201 gattttatct actatttcaa aaaagacccg aaaatcgaca aagttacagg aatttatagc
     7261 gaaattgacc gactgtacgg aattgctgat gattccagtt tttcaagtga ttcaaacaga
     7321 ggtgataagg acctcgttgc tgttgtcgaa aaactaggaa gtgaggccag tggaccatat
     7381 gcaagtctta aagtcgttga tatacccgat ggggctgagt gggaaataag tgattatgac
     7441 ggcgttgaaa ctgcacatta tggttttcaa acaggtagta tttagtccac taatgacaac
     7501 taaagaggag gcagaaggat gagtgaagat gaatactttg aacagtagtc tattaacgac
     7561 agagattttt aactggaaag gggtgtagtc atggacgcat cggaagtagt aaataaaatt
     7621 aatagtctca aagaggtttt cggagacgtc gaagtagtga taaacgcaca aggctatgac
     7681 aacgaatttt ttaagcagat taccgacatt agcattcagc aaggaatgga agacgaagac
     7741 ggaaacttta tcgatgaagt agccatttta gtgacttgcg agtaagtaat tgacagctaa
     7801 agaggaggaa gcggaatgaa actaaaagac ggattttact ccagcggcca cggcatcggc
     7861 ggtttaatgc tagatatgcc gacaaagaat cctaaaacac gtaagaaacc aaaattcaaa
     7921 gtcggtgaca tggttcgctg cgaagcagaa ggattcatct atccatttcg tggatatgta
     7981 gaacacgtct ataatcactc agcaatcatt cgcattgaaa acacgatgga atgtgataag
     8041 tggttagcga aaagcaaaga gaatttagca gtggtgagat tggtggacat ggaagttata
     8101 aaatcttaat tttgcttttt tacaactatc ctacaacaat gagcgttatt ccacaactgg
     8161 aaggagaaga ggcaattgtg aacattttag agaatataga tattaagcaa acaaggaaaa
     8221 atgctagacg attactaaaa agatacagaa atttagaacg tttggtcgga ccagtgaaaa
     8281 tagacttttc cgtgatgact gttaccaaaa atttgaaatt cacaattgac agtcaaaacg
     8341 aagaaatcat tgaagcgata agtactcgag attcggttat cgaagcatta acacggctaa
     8401 gtagaatcca tttccaggta ctttattata gttattgttt tcctaataag atgtcaatgt
     8461 atcaaatagg agaaaaatta ggatattccg atagaactat cgagagaatg aaggcagtag
     8521 ctttggttga atttgctgag gcgtataaat caggagaact catttcacgt acaaaataaa
     8581 aaaagtcgga ttcctccgac tatgaataat atttccgaca taagtattat atcataattg
     8641 ggggaatcag aggatggtac ttttcgatgt aaagaaatat gagacaccaa gcgcgaaaga
     8701 tgttgatatg gaacgcacaa aacataatgt cgctgtgttt ctttcagcat atctatcagc
     8761 tagatgtaga gtagggcaac atcgagaacc aaaagtgaca gcatcttatt ccttggttcc
     8821 accttctaca gctgatcata tatttgaagc agaaagaatg ctgatcgata aagaagaagc
     8881 acaggaagaa tttgagtatc tgcataaatt gtttgttcga ggctattcag cgatacagca
     8941 tccgcataag cctgatgtga ctgaaaggcg caagaagata ttctatgatc gttatatcaa
     9001 tggtctgccc atttatgtaa ctgctcaaag gaataatact agcgaagaat cggttaaagt
     9061 agaatcaaac agaattatca tccaatttgc ttcatcgtta gaactggttg ctttcaagta
     9121 gccagttttt acacttttta taccctttta ttaccaattt ggtttccatt ttataccttt
     9181 tttataccaa tcacttacct attcaacgtt gtattatgat agtgtcgaaa aattaggaaa
     9241 caggatcgac aaaataaaat gtaagggagg aaatctccct catcgtttaa ttaagcttcg
     9301 ataggcagca acggaaatat taagaataag gatgtgaatt tcaactcctt ctaaattgtt
     9361 cttattatct atcatccgtt gctgtctatt gtttttttaa ttattcacac gataactaaa
     9421 ggtaagtgaa gagaaatgat tccattaata atttcaattt ttgcgctttg tcttaatgta
     9481 tatatgattg gatttaaaaa tgggcaaaat aaaaaatagt agcagccaag aataatttta
     9541 tagtgtcact gtggcggaaa gggtagacgc taagcatgtg tgctaggtca atgcttcggc
     9601 aaccatgcaa ggttcgattc cttgccagtg actttggcaa ccgaggcatc ggcggtttaa
     9661 aaatataggg gtgcgcaatt tcgtacgcgt tttgtgcatc gtgtaggttg ctattacata
     9721 actggttagg ttagattgag atttgggatt cggtacaaat gaatcgtcaa atgtctcaag
     9781 cacaggatcg gaaacgtccc tgcctgtgca ttacatatta gatcactctt tgagtggtct
     9841 ttttctttac ataaaggagg ctacataatg agaaactact ggtatgtatc gctaactaat
     9901 gaatatcctc gaaccattga tgattgttca gtgcgtgttg tgcgttctgt acaaatcaaa
     9961 gggaagtact ctattgtcga aatggggaga gaagcagaac catgtgagat tgatgcgtgc
    10021 aagctcgttt attgcggtca tggtttctat gatgaaccaa acattcaaaa taatattaac
    10081 aagaatttga gggattagaa tgcaagaaat ggcttaaaaa tctccaatca ggacaaatca
    10141 agttagacaa agtttccgat ttaaagatat tgattgaagc tgatttaatg ctaaaagata
    10201 ttgaaaatta gaaaacaaaa ctcaacctaa acagaatgtg aggtggtgtg tattgaatgg
    10261 caagacaacg tgatccaaga cgtgatgaag ccaaaagaat ttggttagaa tccaacggag
    10321 aaaagcagtt aaaggaaatt gcatctgaat taaatgtttc agattctcag gttagaaaat
    10381 ggaaatcgca agacaaatgg agcgctgaat tgattagtaa cgttaccaat ggcaaaagta
    10441 acgttactaa tcaaggtggc gctcctattg gtaatcaaaa tgctaaaggt aacaaaggaa
    10501 atagccgagc ttctccgcca gtgggtaata aaaacgcttt gaaaacaggt gagtatgaaa
    10561 caatattttt tgacacgtta accgataatg agaaggacat ctattctagt ttgaatgatg
    10621 atccttcttt tgctttgtcc gaagaaatac gacttcttaa aataagacaa cttcgaatga
    10681 tgaaaagaat ccaacaagct gaagctggac taaatgatga agaagtcgaa cgattgcagc
    10741 agctaagaaa gattaaaact ccgattgaaa aaaatggtaa aaagctagaa atcaagcgtg
    10801 aggttatgca agatgtgcag attagcagaa aaaaacatcg caaaattgat gatattcttt
    10861 caattgaaga ttcattgact cggattagca accagttagc taaagccatc aagcaaatga
    10921 atgaacttta tatgaatgaa tacagaactg atttaattaa agctcagact gataagatcc
    10981 aagctgagac aaatgaaatt ggcggaaata attcaggtga agaaatagaa gaatggaaac
    11041 aggcagtttt aaatgccgca aacaaacggg cggtgaaaga aaatgaataa tgaatttatt
    11101 ccttttgctg atattggttc tgccattgat tattactatg ataaaccagt agctttttgc
    11161 caagatattt tgcatttgaa tcctgatgaa tggcaagaaa atgttttaaa tgatttagct
    11221 gaattttcaa aggtttctgt tcgttctggt caaggagttg gaaaaacagc attagaagca
    11281 ggagcaatac tttggttctt aacgtgtcga ccctacgcta aagtaatagc aacagctccg
    11341 acaatgaagc aactttacga tgtactttgg gcagaggtag ctaaatggtt aaatgatagc
    11401 ttgatcaaaa acttactgaa gtggacaaag accaaaattt atatggttgg tgattcagag
    11461 cgttggtttg ctacggctag aacagcgact aaaccagaaa gtatgcaagg ttttcacgag
    11521 gaccatatgt tgattgtggt agatgaagct tctggtgtgt ctgatccaat tatggaagct
    11581 attcttggta cgctatcagg ttttgataat aagctgttga tgtgtggaaa ccccaataat
    11641 attgaaggtg tcttttatga ttcccataat tcagaccgtg ataaatacag agttcataaa
    11701 gtatcaagct atgatagtaa acgtacaaac aaagacaata tagaaatgat tcttaaaaaa
    11761 tatggaaaag aaagtgatgt tgctcgtgtc cgtatttttg gagaatttcc gaaaggtgcg
    11821 ttggattcat ttatcagtct tgaaacagtt gaattggcta cagaaaaaca aattagtgat
    11881 tctttagtca ataaaacaaa ggttgctcat attggtgtcg acgtagctcg atatggtgat
    11941 gattctacga ttctctttcc tagaattgct accagggcat tggagtatga gaagtattca
    12001 aaacgtagca ccatggaaac aacaggatat gtcatcaaca tggccaagaa tctaatgagt
    12061 caatatccga gtattgataa agtgatgatt aaagtcgatg acactggtgt cggaggtggt
    12121 gtaaccgacc gcctagaaga acttatagaa gacaaacatt atccttttga ggtgtttgga
    12181 gtgaataacg gttcaacatc agaagacgat ttttacgata atttaggtac tcaactatgg
    12241 ggaaacatca aggaaatgtt agaagaaaat atgacagcaa atcttaacgg agaacagcct
    12301 gttattgaat tgccttctga tagttcgtta atcaaagaat taagtactcg caaattcaaa
    12361 atgacaagta gaagtcgtat acgtttagaa agtaaagatg atatgaaaaa gcgaaatatt
    12421 ggtagtcccg atattgctga cgcactggct ttagcgtttt atgagccacc aagtcactat
    12481 caatttattc aattttagga ggtgagcttt tgattagtac agtattatct ttagagagat
    12541 ataagaagct acgtgttaaa tatgcaacac aaattgaaga tggaatgttt gatccgaatg
    12601 gttttataga agatatgaaa ccattttttg ctgatcgcga aagaaaatat ctagcttata
    12661 ctagcgaaaa gaatgaaata gataatagac caaagcctaa cactgatatt gtaaaagtta
    12721 ataataaact tcatgctggt atgtattcaa ttgtcgtaga ccaagcagtc aatcatttta
    12781 ctggtatacc tatcaaatgg gattacgatg tatcggaaca aaaaagaaca ctcattcaaa
    12841 gattaaaaga taaattctta aaaaatgata tagaacttcc gacagttcca gaagctttta
    12901 acaaattaac aagcaatctt gattccatga gattcgcaat gcttgattct gaaactgcaa
    12961 cttttcaagg agcttgtgga gtagctttcc gattgctaga gcctgtggaa gaagatgatg
    13021 gttggaagtt aagagcaagt aatattgaac cttggagagc agaaagatat ggaaatgccg
    13081 gaatctatat caaagaaaag tatgactctt accagaaaaa attttttcaa gaaatgaaag
    13141 ttatgacaag aaataaaatt ctgacatatg cttgctatgg tgatttgaat tttgttacaa
    13201 gcggaacgtt caaaaaaatt gatgagaccg ataacccttt ggggacgatt accttggcag
    13261 aatttaaaaa taatacgaat cgttattgtg attttgaagt agctgaggaa attggagatg
    13321 caattgatcg tgctttgtct gatcaacaaa acgaaatcga acaatttaag cttgcgtaca
    13381 tgcttgttac tggcacaaca atgagcaaag gcactgctaa agaaatgatg aatcagctag
    13441 ggattatcaa cttaaaagcc cctactgcaa aagctgaata tgtcacaaaa aatttagcaa
    13501 aagatttcaa tgaatatcat atggatctat tgaaaaaaca gttttacacc atttgtaaag
    13561 caatcgattt taacgatgag gtgtttaaat caaacagttc tggagaagct cgcaagtggc
    13621 aaatcattag cctagaagcg aaaacaaata ctaaagagca atattttaga gaaggattga
    13681 aagaatgcgc agaaacaatt gctgcttttc ttaagtttca tgacaaagta gaaattgagc
    13741 ctgaaaaaat tatttttact ttctctagat ctttgccaac tgatttaagt tatttagctg
    13801 aagctttacc taaacttgca ccatacgtat ccaaacgaac tattcagagc caaattccat
    13861 ttgtaacaga tgttgattat gaaaatgaaa tgatggaatt ggaaagtgga agtgcttatc
    13921 cagatagtga atacaatttt ggcggaggtg gcaatagtga cgatagaaac gaagtattgg
    13981 accaaacgtc gagaactgga ggatcaagca aggctcaaac aagaaaatca gacacttaaa
    14041 aaattaacta gtgtatttcc tgaagcactg aaagagatac aagcaaaact attatcacaa
    14101 gctgacttac acaatatcac ttatccagaa atgatggagt tttacagtac aagtaatcag
    14161 aaaaaatatc gtgaatatgt ggaaaaaaat tataagtcat taaaaatgta tgatgcaaaa
    14221 tacaaagagt ttatcgatga attttttcca ccatttgact atgcaaaagt caatcgctta
    14281 ttacaaatac gatcagatgt atttaaaatt cttgcagaat atgcgatgga tgcagatgtg
    14341 aatcaatatt tttctgatcg cttagaggaa attcttcaaa gaacatattc ttctaatgct
    14401 aatgtttttg ttcaactttt aaacgttgat ataccaaatt atttaccaga aaatgaaatt
    14461 aaacattatt tgaactatcc atggtcagga aagacatttt caagaagact ttggggaaat
    14521 atttcatcgc ttgaacagaa actctctaat gctattgtaa aaagtgttgc tagtggagaa
    14581 ggcgttatac acgcattaaa caccatgaga ttagactcag aaatttgtga catgtttaag
    14641 ttagaagaat caaagtataa caaagcgata gaaaatctcg ttcgaacgga gtatgcaaaa
    14701 tttgcacaag atggtattga aaaatcatat ttagaaacag gtattgagga atacaacgta
    14761 ttgactgcaa aagatgagag agtttgccgg atttgtggag gaaaggcaag taagaatccc
    14821 tataaactga aagatgctgt cataggtgaa aatcgagcac ctttccatag tcgttgtaga
    14881 tgtacggatg ttcctaattt accaaaatta ggaaaggata ttgatgaaga atatgaccgt
    14941 ttatttggcg atttattaga tgagtttgca catgattctt ttggaattaa tttgaaacgg
    15001 aggaagtaga atgaaagatt tttttgaagc agtactaaca attaatgtaa atgctgatat
    15061 tgcagaagcc tacaaaacag ctattgagtc tgagaaccat cctaatggct tgagagacca
    15121 ttggaatggc aattatgcct acgtggttat tggcgatcaa actgttaatt atcaagataa
    15181 tactccagtt gataagaata ccgttaattt aacgattcaa ttattatctc attcattacc
    15241 aaatttaaaa gaaacagttg attggtatga aaagatggga tgtattgttg ttagaactga
    15301 ctacaaagaa ggaaagtcta gtaattaggc ttttttattt tgtccgaaat gacgttaaac
    15361 tagcgcaata ctgggcttgg ttgaatggtg gggcgcaact attaaaactc aaagcaatgc
    15421 ggggcgtgaa aacgaatcgt ggggcgaaag gagaatgagc atgaaacaca aatcattaat
    15481 gccaatgaat ttgcaatact ttgccgaagg tgacgatcaa aagttttctt ttgatgactt
    15541 caaatctttt gtggaatcca atgaagaagc tcaaaaattt attcagtcac aatctcaaag
    15601 tgttgccgac aaacaattgg aagcttggaa acaaaataac ttagataaaa ttaaacagga
    15661 taccatcaag gaatatgagg aatctaagaa aaacaagtca cctgagcaaa ttcaactgga
    15721 aaaactacaa gctgaatttg aagcagaaaa agcgttgcgt gtgacaagtg ataataaagc
    15781 atttgttgca gaacaaattg ctggattaga actagatgga gagttaaaag agtctatttc
    15841 tcaatttatg ctaaataatc ttgttagttc ggatacagat ttcactaaga atgctgttga
    15901 aggttttaca agtgttttga atgcaattaa tgagaaacat gcagatgcat taaaagaact
    15961 acaaatgaag tctgcatttg gtggaactca acaatcgaat aaccaggttc agcagaacaa
    16021 tgaaacatta acaaatccag aagaacaatt aggacaaatt cttcaacaat ttaactagga
    16081 gagtgaaaaa ttatgaaaaa aacatcttta aataatttag agtatttgga tatttcacca
    16141 gcgattaatg ctatgcaagt accaaataca ccttttttaa gctatttact tggtgctgga
    16201 aaaacagagc cagcaaactc gacagaaatt aaatggcgtg aatatgatat caacaacgat
    16261 gattcttctg aaaaacttga gggcggagaa tatccagatg ctgaatcagg tcgaacttgg
    16321 tttaacaact atactgaaat ttttagaaaa tcaacctctg tatctggtac attagatgct
    16381 attaatgtga atggagtcgg aaatgaatta actaatcaag tagcactacg tggtatggaa
    16441 atgaaaattg atttgaaccg aaaattgatt actggtgtaa aagctgatga aaatggttct
    16501 aaaggtcgtc gaatgaatgg gattttgaac ttgatcaatt cagcaaataa ggcagaaaca
    16561 gccactgcgg gtgcagtaac aagaaaagat atcgatactt tatttaaatt gatgtatgaa
    16621 aaaggttata tgggagaaaa actatgcttg atttctccag atatgcagga gttaatgact
    16681 gatgagttag atggaaaatc aacaaaaatt gttcagttcg gggaaagagt aacttttgga
    16741 ttgcaaattg gaaatatcgt gtctaattac ggtacaggta ttgctctact agaaccatca
    16801 ttgccaaaag gaacaattgc cgcaatcgat actaattatg tgaaactacg tccattacgt
    16861 gaatggagag cagaagaact tgcaaaaaca acggattcta gacgtatcgg tcttgtaggt
    16921 gaatactctc ttgaatacaa tgcttcaaac tctggggcaa ttttaaattt aaagtctgaa
    16981 taaaagggag ttagtactcc cttttttgat aggaggaatt acagtggtaa aaaaagatga
    17041 aactaaaaaa gatgaagtcg tgaaatatag agtaggtaaa actaaaaatt ttgttgggtt
    17101 tgttcatcct aaaactcgta gatttatcac agcagattca aataacgaat ttatcatttc
    17161 tatagatgat aaagaagcaa ttgcaatttt ggaagatgca attgatgtta atgaaattta
    17221 ggaagtgatc tgatggatga atcgctaaaa acggaaatca ttgagtctac aaaagaagat
    17281 tttccagatt tgagtgaaga acgcataact aatttattag aaataatttt gctagaaatt
    17341 gaatcataca acacttgtaa aaatgatatt tcatgggaaa agttaaaaag cgtgattagt
    17401 gaagtgttgt ataaaataat aaaaaatgaa tcagaaaaaa cagtatcttc agttagacgt
    17461 ggcgatacaa cgattagtta tgcttcaaca acaaatgatg ttagtgagtt acttctaggc
    17521 tatggtgatt tgatacgaag agttattggt tgtggaggat tggagttttt ttaatgaatg
    17581 aagcagatat tttagaaact acttatgaag atagttgtat tattgaaaga ctgacggaca
    17641 ttgaagattc taatacaaat attactattc aagattacaa aaaagtatat gataatccta
    17701 tttcttgcgc tctttcacaa ggtcaaatcg atggactagc agtcatagaa gatggagaga
    17761 tggtaaatgt ttcaactgac acatataaat tatttgttca tcctaagatt aaactaaaaa
    17821 aaggagatcg aataacaata actcaaaagg ccagtggctt aattttttct ctatttgcta
    17881 ctaagccttt ttactatcct agtcattgtg aagtgaattt gataggaagt gagaaaaatg
    17941 ggtaatctca aatatgaatc aaatgcagaa aagatcattg agaattttaa aaatatgact
    18001 gtaattgctc aaaaagaagg aatatccttc gttaacgatt caatgaataa agtcgttagt
    18061 ttagctaaac cattaactcc tgtaaaatca ggtaatttaa ggcgaggata tcgtgtagta
    18121 aaagctagaa aactatcaag cggtcgaatt gttggagaag ttataaacaa tgaacattat
    18181 tttaaatatg tagaagaagg tcataggact aaaaatggtg gctttgtcaa agggaaattc
    18241 atgttaactc gtgcaacgaa tcttgcaaat atgtcttata ttcctcgaag atttaaacaa
    18301 atggcaataa aaatcgttaa gaaaggaaag taacatgaaa gatgaaatca ttgctgcaat
    18361 cagtagcaaa ttaaaagaaa tctatcctga tgggacaata tatcttgatt cagttatgca
    18421 gtcaactaaa gatttttatt tcgttttatc agtaatggaa tctggaactg aaaatgtagg
    18481 aattgatatt caaaatgttt ctttcttaat tgatattgca ttgattgata ataaccctaa
    18541 tagaaattta attaatgaat tagtctcacg ttgtgggact ttttttaata cgattacaat
    18601 cgatgagcaa atattatttc caaaagccta tttacctgat gaagcagatg gtgttcaaca
    18661 tattcgtttt acattagaat ttccacaata tattgaatgg agtgaaagat aaatgggaga
    18721 aaaaagaagt aaaaccggaa ttatttctgt cgaaaaacct acttggtttc ctttggaaga
    18781 tgagacaggg aattttccgg tatatggtac tgcgttgcca atgggaacag cagtaagtat
    18841 caaaccaaca gctaattatg aaacaacaca agattatggg gattcagtgg ttcaagatca
    18901 atttacagct tttggtggtg cagaagttga actggaagca aatggatata ctcataaagt
    18961 tttatctaca attactggag ggaaaattgt taaaggtggt gccttgcgtt ctggagaaga
    19021 tattgcgcaa gatggtgcgt ttgcatatag acgtaaaaaa tcgaatggga aataccgtta
    19081 tacggtcttt tataaaggac agtttgctct agattcagat gaaacatcaa cgattgaagg
    19141 aagtaaagta agttttactc atccaacttg gaagggttca tttgtagatg taccaggact
    19201 tggatatatg tattcagttg atgaagatga tgaaggcgtg gataaagcaa tgatcggaaa
    19261 ttggtttaca aaagtagcaa ttccaattga agaagcagaa ctttcaggag gtacagaata
    19321 atgtcaaaat atcaaacaac gattaaatta acgaaaaaag acgaagaagg taaatatgag
    19381 caagtacaat ttaaatctgc tgaattttta ccaggaacag ttgtagaaga tgctgcagga
    19441 gttatggaag aaatgcaaac agcgactgat aagcaatcag ttaaaaaagc tttaagtcgt
    19501 gcttattcat ttattgcaga tactttattt gagggacaat ttactggtga agattattgc
    19561 aaaggaattg atgctcgtga gattgcctca ttgacaggaa aattattgaa gtctgttact
    19621 gcaggttttg atgaaactta tacagagacg aaaaaaaagt aagtgaggcg ctcaagtcac
    19681 cttcatttaa gtattcgatt acttaccgag aattagatat aaagacgcaa ttactcgaag
    19741 caggttggac gttaccagaa attgaacgta ctgacttgga tgagttaatg cgtctttttg
    19801 cttttagaga tgcggtaaaa gagcatgaag atgttgagta ctatgataat ttcactcaat
    19861 tttaggaggt gatactttga ataacgatga cctaattctg aagatgatac tagatgaatc
    19921 tggttttact gccggtatga ataatgctgt caaaaagttg aactcttttg atgaaacaat
    19981 cgaaagaaaa agtagaaata gtggcagttc attaggtagt atttggaaaa tatttgctgg
    20041 aagttttcta gctagcggag taactagaat cgtaggagct ggctttgatc taatcaaggg
    20101 ttccataagt ggagcggttg atcgagtaga tacgatgaat aacgctctac gaaatttcca
    20161 aaatatggga tttagtaatt cagaaattat gaagaatatc ggaaagaatg ggcttttatc
    20221 tcaaggtatt caaggacttc ctactgcttt gaatgatgcg ataagtcatg ttcaacttct
    20281 tgcttcttct acaggtgatt taactcgttc aactcaaata tttaaagctt taaatgatgg
    20341 aattcttggt ttcggtggtt caactgatca agttaatgaa gctgttattc aattatctca
    20401 aagtttctca aacggaaaag tagacgcaca aacttggaac tcaatgatca acgctcaact
    20461 tggacctact ctttctgcta ttgctaaaaa gatgggaatt acaatgggag atctgaaaga
    20521 aggtttatct caaggtaaga tttctgttga agaattccaa aatcaattaa tagaaatgga
    20581 taccaaaggt ggcggaggac ttaaatcatt aagtcaaatc gctaaagatt ctactaaggg
    20641 aattaaaacc tctatacaaa atgcaaaaac agctgttaca cgtggtgttg gtgaggtaat
    20701 agaaggatta aataaagcat tagtagattc agatttaggt ggatttaagg gaattattga
    20761 taaagtgggc agttcaatgg aatcgttctt aaaagtaatt gctgcaaata ttcctacagc
    20821 agtatcattt ttaagtaatt tatttaacga aattcaaaaa tttggttctg ctttgaaatt
    20881 catgatgccc tttcttgttc ctgcagctac cgcttttgga gcgttcatgt ttcaacttaa
    20941 aggtatacca gcaataataa aaagcttcaa taattttaag aatgccataa ttggcgttgg
    21001 aaattcatta aagattatgg gggcaatagc tgctgctaat ccatttgttt taattattgg
    21061 tgcagtcgtt ggtgcaatag ctgttttcgg ttactttatg gcaaccaatg aagagcttag
    21121 aaacaaggtt atatctattt ggaatgatgt gaaagattcc gtaattggtg tattaaaaaa
    21181 tataaaggac tggggaattg atacttggaa ttctgctaaa gaaatggcat caaatgcagt
    21241 tgagggtgtc aaagatgctt ggtcaggaac aaaggaatgg ttttctaaca cctggaaagg
    21301 tattaaggat ggggccacag gtttatttga taaaacagta gagacttcaa gaaatgcagt
    21361 cgatagtgta aaaaatgcat ggtctaatat gaagaaatgg ttttctgata cttggcaaag
    21421 tataaaagat tcagccagag aaaaatggaa tggaatcaaa ggttctatta tgtcagttgc
    21481 tggtccattg attacaggta taaagaatgc atttttacat gttacttttt atctagagac
    21541 cttatggaat aatttagttg agattggtaa aaacgtcttt gagattttaa aaaatgttat
    21601 acttgcgccg gttttgttta ttacctccat gatttctggt ggatgggaag aaacaaaaaa
    21661 taatatgatt gctgtttgga ataatattaa agaaagtgcc ataaatattt gggaatctat
    21721 aaagaat
//
LOCUS       DAZUJR010000050        21302 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.050, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000050 DAZUJR010000000
VERSION     DAZUJR010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21302
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.050"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(26..1522)
                     /gene="lysS"
                     /locus_tag="ACG804_001782"
     CDS             complement(26..1522)
                     /gene="lysS"
                     /locus_tag="ACG804_001782"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HFS4832711.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="ACG804_001783"
     CDS             complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="ACG804_001783"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HFS4832712.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVDCREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="ACG804_001784"
     CDS             complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="ACG804_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HFS4832713.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3742..5853)
                     /gene="ftsH"
                     /locus_tag="ACG804_001785"
     CDS             complement(3742..5853)
                     /gene="ftsH"
                     /locus_tag="ACG804_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HFS4832714.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="ACG804_001786"
     CDS             complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="ACG804_001786"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HFS4832715.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="ACG804_001787"
     CDS             complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="ACG804_001787"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HFS4832716.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8053..8523)
                     /locus_tag="ACG804_001788"
     CDS             complement(8053..8523)
                     /locus_tag="ACG804_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1 domain-containing RNA-binding protein"
                     /protein_id="HFS4832717.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8569..8994)
                     /locus_tag="ACG804_001789"
     CDS             complement(8569..8994)
                     /locus_tag="ACG804_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HFS4832718.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9061..9330)
                     /locus_tag="ACG804_001790"
     CDS             complement(9061..9330)
                     /locus_tag="ACG804_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HFS4832719.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9341..10936)
                     /locus_tag="ACG804_001791"
     CDS             complement(9341..10936)
                     /locus_tag="ACG804_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFS4832720.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="ACG804_001792"
     CDS             complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="ACG804_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HFS4832721.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14489..15049)
                     /gene="pth"
                     /locus_tag="ACG804_001793"
     CDS             complement(14489..15049)
                     /gene="pth"
                     /locus_tag="ACG804_001793"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HFS4832722.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15402..16376
                     /locus_tag="ACG804_001794"
     CDS             15402..16376
                     /locus_tag="ACG804_001794"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFS4832723.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16546..17946
                     /locus_tag="ACG804_001795"
     CDS             16546..17946
                     /locus_tag="ACG804_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HFS4832724.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18024..18746)
                     /locus_tag="ACG804_001796"
     CDS             complement(18024..18746)
                     /locus_tag="ACG804_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4832725.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18825..19331)
                     /locus_tag="ACG804_001797"
     CDS             complement(18825..19331)
                     /locus_tag="ACG804_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFS4832726.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19454..21253
                     /locus_tag="ACG804_001798"
     CDS             19454..21253
                     /locus_tag="ACG804_001798"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HFS4832727.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLFQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
BASE COUNT         5925 a         4668 c         3840 g         6869 t
ORIGIN      
        1 aattccttag acagctttta ttcgattatc tcattgttgg gaatagcaaa acatcccgaa
       61 ttgattgtgc atcagttagc aacattacta atctgtcgat cccgatgcct agaccaccag
      121 ttggcggcat accgtattct aaggcttcca agaagtcttc gtctacaccg tgagcttcgt
      181 catttcctag ttcacgttct ttttcttgcg cttcgaatct ttctctttga tcaattggat
      241 cgttcagttc tgtaaaggca ttagcaaatt cgcgccccac tatgaatagt tcgaatcgat
      301 ctgtgaatcg aggatcttct ggatttttct tcgctaaagg cgaaacttcg actggatgtc
      361 cgtatacaaa cgtcggttgt gtcaatgttt cttcaacaaa tgtttcaaag aattcattga
      421 taacatgtcc gacacccata gcttcggtta cttctacatt gtgtttttcg gctaaagcta
      481 atgcttcttc caatgtcatt tcttgccaga agtctacacc agtttgttct ttgattgcat
      541 ctaccatatg gatgcgttta aagtcacttt ctaagtcgac agcttgtcca tcatatgtga
      601 tttttgctgt tcctagtact ttttcagctg cgttacggat aataccttct gtcagattca
      661 ttacatcatt gaaatcagta tatgctgtgt atgcttctaa catcgtaaat tctggattat
      721 gtgtagtatc aattccttca ttacggaaaa cgcggccgat ttcataaact ttttccattc
      781 cgccaacaat tagtcgtttt aaatgaagtt ctagcgcaat acgcaaatat aaatcaatgt
      841 ccagtgcatt atgatgcgtg ataaatgggc gtgcggcagc tccacctgcc tcattgtgca
      901 atactggtgt ttctacttca atatagccat tgccatctaa atagcgacgg atttcgctga
      961 taatttggct tcgtttcata aatcggtcaa agctttcgcg attactgatt aaatccaagt
     1021 agcgttgtct gtagcgttgt tcaatattcg ttaagccatg gtatttatct ggcagtggac
     1081 gaagtgcttt tgacaaaatc gtgatttctg aagctttgat agaaacttcg cctgtgtctg
     1141 ttttcatgat ttgtccagtt acaccaaaga aatctccaag gtctgcatgt ttgaatactt
     1201 cataggcctc atcacctact tggtcttttc ttacataaat ttgaatttgg ccttcacgat
     1261 cttgtagatg cgcaaatcca gttttccctt ttcctcggcg agtcatcata cgaccagcta
     1321 cactagcggt caatcccatt tctgctagtt cttcttttgt tcttggatca aatagttcat
     1381 gcaattcttc tgagttgtgc gtgcgttcaa atcgttttcc aaatggatcg attccatctt
     1441 cacgcaattg ttccattttt tgacgacgta caagcatttg atcatttaaa tcttctactt
     1501 gatgttgttg ttcctgtgtc acaaaagttc ctccattctc atgttaatct ctttcctata
     1561 atgccaatga aacacaaaaa aagcaagccg aacttggaat ttcggcttga aaattcacga
     1621 aaaacttaga aatcacaacg tttgtttcaa tagtactttt tccgcttttt ctacaaattg
     1681 atccagcagg tcattgattt cttgctgttt ttctgtctga ttgattgcta ctttcacttt
     1741 cgctgctcga ggaatccctt ttaaataata agccgcatgt gttctgaatt ctctacaatc
     1801 tactttttct cctttgagat ctgctaagcg ttgtaaatga agtttagctg tagcaatttt
     1861 ttcggctggt gttggttcag gaatcagttc tcctgtttcg agataatgct gtgtgcggtg
     1921 aatcatccat ggattgccca gcgctgcacg accaatcatc acaccgtctg caccgacata
     1981 gtcaagcatc cattttgcat cttctggcgt tttgacatcc ccgttcccca taaatgggat
     2041 cgtcaaatgt tttttcactt ctttcaatac ttcccagtcc gcttttcctt catacatctg
     2101 aacccgtgta cgtccatgca tagcgatggc acttgctcca gctgattgtg ctgctaatgc
     2161 attttctaca gcaaagacgt gctcttcatc ccaaccaata cgcatcttga ttgttactgg
     2221 gatatttact gctgaagaaa cagcttggac catttcgtat actttctcag gatctaaaag
     2281 ccattttgct cctgcttctg ctttgattac tttatttact ggacagccca tattgatatc
     2341 tattatatcg gcagctgtgt tttcttcgac aaattgagca gcttcaacta gactatcttt
     2401 atttccgcca aatatctgta aacttaatgg atgttctgtt tcttcaatgt ggagcatctc
     2461 taaagttttt ttgtttctga aatgaatacc ttggtcactg atcatttcac atacgactaa
     2521 gcccgcacca aattctttga cagtgactcg aaatgctgaa tttgttattc cagccatcgg
     2581 tgcaacaacg acacgattag ggatttccac attgccaatt ttccatgtgt gttccactta
     2641 aatccctcct aaggcttctt tcttcaatcc atctaattct tcttcgctat acttgtattt
     2701 gttattacag aaagaacaaa ccgcttctgc accgtgatct tcgtctatca ttgcttggat
     2761 ttcttctgca cctaacgcga taattgcttc tgcaaatttt tcttttgaac agtcacattt
     2821 gaattgaaca ggcatttttt ccaaaatgtt caattcttct gtaccaagca atcctttcaa
     2881 tatttcttct ggtgtctgtc cttcatctaa gagggtagag attcttggtg tcgtttttaa
     2941 ttgttcttcg atcttgctga ttgtttcttc atcggcacct ggcatgattt ggatcatgaa
     3001 tcctcccgcc gtcttgatgc tgtcgtcagt attgaccaat acactcagtc caacagctga
     3061 agggatttgt tctgagatag caagatagta agtaaaatct tcagcgattt ctccagaaac
     3121 aatcggcgtt tgcccagaaa aaggttcttt taatcctaag tcttttgtga cagtaaacat
     3181 tccttgtgtt ccaactgctc cccgcacatc gattttacct tcactattta gaggaagact
     3241 gagatgcgga tttttgatgt aacctttcac atctcccttt ccatttgcat ctactacaat
     3301 tcctgttgct ggaccatcgc cttggattcg aacagttagt ttgtcttctc ctttgagcgt
     3361 cgcaccaagt agcagactac cgaccaatgt ccgtcccaaa gcagctgagg aggtgtgcca
     3421 agtatcatga cgtctttgtg cctccgctac ggtatttgtt gcttgaacgg cgtatgctcg
     3481 gacgaatccg tcgtgagcaa gtgccttaac caaataatct ttcatttgtt atgtactcct
     3541 ttttccgttt ttaaactcat agtgaatcat actagcaact actgcttttt tcaactttgg
     3601 aatgcttctt ttaaaaataa ttcagaatca tctagaaaac aggacatcac cctatttaca
     3661 acttaaataa agaaatctcc cgaaaaccgg tttttgttcc ggttttcggg agtcatatca
     3721 gatcaattga cctatatttt tttatttgta ttgatcgtct gaatgattat cttctgattg
     3781 ttgagaatct gaatcatgtt ctgctttatt ttcctcattc agttcatgtt ttgcttcttc
     3841 aaaatcacgt ttttcttccg cttgtttttc agcgtctttt tcttccaaag cacgttttgc
     3901 ttcttcaaaa gttttcgctt ctttttcgct tggataatca tttgactcag taccttcagg
     3961 catcacaccg tgttcaaaca atgacttgat tgctttggca tccaatgttt cgaattccaa
     4021 aagtttttca gcaatcagtt tatgctgtgc acgatgagct tcgatgattt ctcgagcttt
     4081 atcatgagct tccatcaaga tttttcgtac ttcttgatca atctcgaaag cgacttgttc
     4141 cgagtaagct tttgtttgac catagtcgcg gccaacaaac acttgatggt ttccttcata
     4201 ttgaacagga cctaaacgat cactcattcc atattctgtt accatgcttc gtgctagagc
     4261 tgtcgcttgc tcaaagtcat tggaagcacc agttgattgg acattgaaga tgatttcttc
     4321 agctgtacgt ccaccaagta agcctacgat ttgttcaaac atatcttctt tcgtcatcaa
     4381 gaactgatct tcttttggta aagcgatcat atatccgccg gcgcgtccgc gagggatgat
     4441 cgttactttg tggacgaccc gagcgcgact caatactaat ccgacaatcg tatgaccagc
     4501 ttcgtgataa gcaaccattt cgcgttcttt tttgctgatt acgcgatctt ttttagctgg
     4561 acctgcaatc acgcgatctt ccgcttcatc gatatcagaa gcatcgattt tctttttatt
     4621 tcttctagca gctactaacg ctgcttcatt caagacattt tctaaatctg ctccggcaaa
     4681 acctggtgtc tgttgagcca caactttcaa gtcaacgtca tctgccatcg gtttattccg
     4741 tgcatggact cgcaagattg cttcacgacc ttttacatct ggacgtccaa ctaaaatctg
     4801 gcggtcaaaa cggcctggac gtagtaacgc tgggtctagt acatcagaac ggttggttgc
     4861 agcaatgacg attactcctt catttccgtc gaagccatcc atttctacaa gcaattggtt
     4921 caatgtttgt tcgcgttcat catgtccgcc gcccataccg gcaccacgtt gacgacctac
     4981 cgcatcaatt tcatcaatga aaatgatagc tggtgcgttt ttcttcgctg tttcaaacaa
     5041 atcacgaaca cgacttgctc caacaccgac aaacatttct acgaaatcag aacccgagat
     5101 cgagtaaaac ggtactccag cttctccggc aacagctttt gctaataagg ttttacctgt
     5161 tcctggaggt ccttctaaaa gtacacctgc cgggatacgg gcacctaatt caacaaatcg
     5221 gcgaggatct ttcagaaatt caacaacttc aactagttct tgtttttctt cttccgcacc
     5281 cgctacatca gaaaaacgta cgcgattagc ttttttgtct gcttctttgg cttttgattt
     5341 accaaagttc atgacacggc cgccaccgcc accgccgccg ccttgttgtc ccatcatcat
     5401 gtaaaagaaa aagatgatga ttacgattgg caagaagcta agcaataggg aaacccatat
     5461 accgctgctt gattcttctt ttactgttgt agcaactttg ttttcttttg ccagttctgt
     5521 tacttggctc aatgttgtat catttggcaa aatgattgtt gtgaaatggg tagtagtcgt
     5581 atctgttgaa cctaagatag ctaacccacc gctgttagcg acggtctgct gttctttgta
     5641 ttcaccagtg atcttatata caccatttgc aggctgcact tcaaattctt tgatcttgcc
     5701 tgcttgtagt tgttctgtga attttgagta ctcgatatct gacgatcgct ggccgttatt
     5761 accaaaaatg aaataaacga ccattaccat cgctaagatt acgaggacat aatacaaggc
     5821 atttttcatc atgccgttgt tctttttgtt catagttgcc ctccctaagc gtcaatttaa
     5881 tttaacagtt ttttatcaat cctgaccatt ctattgtacc ataatttaat tgagatacag
     5941 cattaatttg attgataaac actaggtttc aatacaccga tgtacggaag gttacgatat
     6001 gcttctgcat aatccaagcc ataaccgacc acaaattcat ttggtacgtt gaagccaaca
     6061 taatctgctt cgatatttac tactcttcct tcaggtttgt caagtagtgt aacaattttg
     6121 actgattttg ctttgcggta tttgaaaaga tccactaaat aagcaagtgt tcttccgctg
     6181 tcaatgatat cttcaacgat caacagatcg cgaccttcta cattcgtatc taagtctttg
     6241 acgattttta cttcccctga cgagactgtt gcattcccgt agcttgaaac atccatgaaa
     6301 tccaattcca aatacgtatc gatagaacga acgatatctg ccatgaatgg taccgctcct
     6361 tttaagacac ctactactag gggattggtg ttttggtaaa tttctgttaa ctctttgcct
     6421 agttctttgc aacgaacttg tatctcttct tgtgagatca aaattctctc aatatccttt
     6481 tccaacatca ggttctcctt ccaattgctt ctttttgata tttgtaaaga agtatgtagt
     6541 gtattttatc agtttcttca cgaatactca aatatgaaaa ggcaaaaggt atcaagctat
     6601 atatatttct tttggcatct gtaatgatcc aagcatgctg cctttgtgaa ttaggtactt
     6661 tctgatcgat aaaatatcta gatacttttt ttgtgagatt ctctgttaat ttaatgcggt
     6721 ctcctgcttt tcttttttcg acatacagtt gcacatcagc aggaatccaa atgtcatgag
     6781 aaaatagaga ccatgaatct gttgctttga tgtcccctgc attttcaggt ttgaccagac
     6841 caatccattc tgtttcattc aaatatattc cttgttctgg aatcagcaac aagcgctggt
     6901 cttctgtctg gctagttgct tgtttttctt ttttagagag tacaacaaaa tgatactctc
     6961 ttttcagtat ccaattattg ccaatactga gttgccattg gctttttttc tgttgccact
     7021 ggtctaaaat cgactccatt tgttgttctt tcaaaataat tcctgttttt gagaatgctt
     7081 tgtcgaaaaa ggagtaaaaa aaatagtatc gttcagcatc tgtcatttct tcaatcattt
     7141 ctgcagaaaa tcgaaattgt tcctcccact gttcgacttc cttttcgatc aactgtccca
     7201 tatatttttg aatgacttgg tctgcccatt ggatctgttg cgaaaattgc tggaaatgtc
     7261 tcaacgcctg tgtattttct tgtttcaatt gaggaactac caaatgacga agccgatttc
     7321 tctggatatc taacaattgg tttgtctgat cctcaaagta aacaagctgc gattccgctg
     7381 cataagtata taggtcttct ttgctaaaac tcagcaacgg acgaatcagt ctgcccgtag
     7441 caaatggttg tacttctttg attccagaaa aagtatttaa ctgtccccca cgaacgattt
     7501 tcattaacac cgtctcgatt tgatcatctc cgtgatgagc agtcatcaac gtgtcatatt
     7561 gtccttcttc catcacgcga gtgaattctt gataacgaaa gttacgagct tctgtttcta
     7621 tggcggattt ggctggatct tcccaaatac ttacatataa agggagattc ttctcttcac
     7681 aatatgagcg aagataggca gcttcttctg ctgattcttc tcttaattgg tgattgatgt
     7741 ggacgatacc taaagaaaaa ccgatttggc gttgcacttg taaaagtaaa tggagcaaaa
     7801 ccatcgaatc aacaccacct gataccgctg ctaaaattct cgatccttgt tgccagaatc
     7861 cttgttcatt cccgtgccga ataaatgact gctgtaatag cggtgctttt ttcccgcctt
     7921 tttcaacgtt catcctttcc acaccctttc ttcctaaaaa aaagagagcg ggaaaacgtc
     7981 taaaacgaca attaacctgc cctctgttga tactatgacc caaatagtcg cactatcatt
     8041 atttgcggct ttttagctgc gacgtccgcc acggccaccg cgctttcctt ctgtgtttcg
     8101 cttcaatgaa gataagcggt catcgctatc tttcaaaaat gaactcatca atgaatcgaa
     8161 gtcttctttt tgagctgaag gttgactgcg agaaaaagat tttttctgtg ctggacgatt
     8221 tcggttgtca cggggatctt tttgttgata ttttttagga cggctttctt ctccagattc
     8281 agcaggttgt tcctgcgctt tccggataga tagtccgatt tttccatcat catttactga
     8341 aataacttta actgttactt catctcctac acttaaaaca tcatggatgt cttttacata
     8401 gccatttgac acttcgctaa tatgaactag acccgttttt ccagcaccta gatcaataaa
     8461 cgcaccaaaa tttgtgattc ctgatacttt tccttgcagt tttgctccta cctcgattga
     8521 cataaaaaaa atgttcctcc taattatttc ccttttttat attcctgctt attttgcagt
     8581 tgtagaacta gttgattgat ctgtttcatt tgtcgagctg tctgtatttg attctaatat
     8641 aggataaact ttttcaccgt cttttgagta aaagaatttg cttctggcaa gtttagctac
     8701 atactcatca tctttcagca atgaaacatc ttggtgcagc tgatcaacgt ctgcgttgac
     8761 ttctttcatt tcagtatttg cttcgactct caattcgttc aattgatgca tcctttgcat
     8821 gtcatggaaa atctgcacac ctattatcgc gaaaatgacc aaagcaccaa caaaaattgc
     8881 agccagtctg cgtcttcgaa aaatcagttg acgttgttgt tgctgaaatt cagcatactt
     8941 tttctttgca tattccgtat ctagcgcagc gattttattg ctttttttcg tcacttggat
     9001 tcgctccaat ctttttgatt gtctttttca ttataccaat atcgtgaaag cttgtctaat
     9061 ctatttctct agtgtttctg tgcgattttc agaaataatt tcgtacattt tttgtgcatc
     9121 ttcttttttg gttgattcat gtaattccgt aattttcact tccaacgttt tgttgccaaa
     9181 ctggactttc aaaatatcgc ctactttgac atcactggaa gatttcgcca atttaccgtt
     9241 gatttgaatt cttcctttat cagctacttc ttttgctact gatcgtcttt tgatgattcg
     9301 ggaaattttt aaaaatttat ctaatcgcat atcttattcc tcacttttta atttttttat
     9361 ttaatcgcag gattttctta ccaaaaggca acattagcca ttctcgtact gtaaacagac
     9421 gaagacgaat cactgcataa atgaacacag aagccccgat cccaactcct atcacgctga
     9481 caaaaaaagc agtggaacga tgagttacag gaccaaatac tatattcaat acaccataat
     9541 acagcagcag tactactgtc atacaaagaa ggctgaacat caacttccgt ccaaaatgcc
     9601 gttctttcca aaaagcattt agctcttttg tttcaattcg aacaaaatac caaagcgtca
     9661 cacctaatcc taaaagggta gacaggcttg cacctgctgt tcctaataaa ccggtcagaa
     9721 aagaagtagt caatcctttt accaatagtc cccatcctgc gccttttaaa gaagggcgaa
     9781 acgagttctt gctttgagca atactttgat aagcttggat gactgcagtg aaagcaatgg
     9841 aaaaaacaaa taatacaagc gctgcatttc ccgcataatc tttaaacaac gcataattga
     9901 tataagggag cagcaaggct aatcccaaag acgcagctaa tgctaaagcg gtcgtcaatc
     9961 taagatagat tttggctgtc tgtaaaaact gacgatagat ccggttggtc aaatgacgag
    10021 tcaacgcagg caggaatgtc gcacttaatg cagtggcaat cactaaacct aattgtacta
    10081 aaggctgacc tcgatcatag accccttttg ctatcttcgc accgtattct gacagtccgt
    10141 aaacttccaa agcatttttt acaaagaaag agtcgatcag ctggaaaaag ataagcaatc
    10201 cactataaat cgaaaccagt ccgccttcta ccagaaaacg ccggatcaag ggctttgacg
    10261 gctgtttgaa caatggaaac cgtcggaagc ttaacgctcc tccatgaatc ttttgttcat
    10321 agtagtgaag gatcccatat gcgcataaac cgccaaaaac agctccactc attgctgccg
    10381 tccctgtttg gtacaccgtc catccaagct ttctaaaagc aaacgcacta cagacaatca
    10441 caaaaacacg aacgaactgc tcaactactt gagaaacagc agttggttcc atcaagaatc
    10501 ttccttggaa attccctcga taaaaagata gaccaggcat cagcaaaaag gtaaaggaaa
    10561 ctacttggat cagcggtttc aattgtatgt ctcccatcat ccaagcaatc cagctgctaa
    10621 atgcaaagac aaacaaccac aaaaagacac ctgtccaaaa tactaaggga taaagatttt
    10681 gcaaagcttg ctttcgctcg aaaggattct ttctttctgc aacgtacttt gatatgaact
    10741 gcggaagacc ggataaagct aaagtcattg ctatcccata aattggataa acttgctgat
    10801 aaacataaaa accttcgtcg ccgactaagt tttggagggg aattcggtaa agggcactta
    10861 atacttttgc tatgaaagaa gcaatcgtca atacaaatgc tccttgcatg acgcgccgca
    10921 tttctttatg atccaaatca ttgctccttc ctacgctgac agatattttt gctcacgcaa
    10981 cgctttgaca aacttttgga tttcctgaag ccatactgct tcttccattt ggttggggat
    11041 cgtcaagcgt atcaccatct gttctttttc aacgcctaga ctggctttta gttttgtcgc
    11101 tgtcagtgct tcgaataact gttccacact atagcgtttt gttccaactt tacttagagt
    11161 aaagactata tgcgcctcct gtttccttat cgtttctagg agcgctcgat cgccatccat
    11221 tttgatctgc ccaattgtca agagatgtgc tacttcttct ggatattctc caaaacggtc
    11281 gagcagatca tcttctagtt catctagcat ttcttgcgaa tcaagttcac gaattcgttt
    11341 atagatctcg attttctgcc gttgatctgc cacgtatgtt tcaggtagat acgcatcgac
    11401 accgaggtcg atctcaacag tggtcttctc cacttgacta ttctttcctt gtttacgaga
    11461 aacagcttcg cttagcattt gagaatacat atcgaaaccg actgcatcaa taaatccatg
    11521 ctgctgagca cctaagagat tacctgcacc gcgaatggaa agatcccgca tcgcaatctt
    11581 gaatccagat cccagttctg taaaatcttt gattgcctga agacgttttt cactgacttc
    11641 gttaaggatc ttctgctgct catacataaa gtaagcatat gcgacacggc tgcttcttcc
    11701 tacccgccct cgcaattggt ataacgtgga taatcccata taatcagcgt tctcaacgaa
    11761 caacgtattt gcgttcggga tatctactcc tgtttcaatg atggttgtag tgacaagaac
    11821 atcatattga ccttcaataa attcaaaaag cgtattttct aattgcgcct ctgtcatttg
    11881 cccatgagca taaccgatcc gtgcttccgg aacgagttct tggatttctt ctactttttg
    11941 ttcgatcgtt tctacccgat tatataaata gaatacttgt ccacctcgtc ccatttctcg
    12001 atggattgct tcgcgaatag ccccaggatt tttttccata acatacgttt ggatcggata
    12061 acgattcgca ggcggtgttt cgattactga aagatcccgc acgcctaaca tcgacatatg
    12121 caaagttctc ggaatcggtg ttgcagtcag agtcaaaaca tccacttgtg cacgtaactg
    12181 tttcaatcgt tccttatgtt ttacaccaaa acgttgttct tcgtcaatga tcagtagacc
    12241 caaatcgcta aattcaatat cttttgacaa aattcggtgg gttcctacaa caatatcaac
    12301 ttgacctgta cgcagttgtt cgatggtttc tttttgttgc tttcttgttc tgaaacgact
    12361 taatagcccg atatttacgg ggaaaccttc aaatctttcc agcatcgttt catagtgctg
    12421 ctgtgccaag atcgttgttg gaactaaaaa ggctacttgt ttgctttcct ttatcgcttt
    12481 aaaggccgct cgaagcgcta cttctgtttt cccataacca acatcaccta cgagtagtcg
    12541 atccattggt ttttcttttt ccatatcccg tttgatctcc gctgcacttc tcaactggtc
    12601 atcagtttca gagtagggga aggcattttc gaattctttt tggtaggcgt catcaggtcc
    12661 aaaagcatat cctttttctg actctcttgc ggcatataat ttgattagat cgtcagcgat
    12721 atcctcgatt tttgaagaga cttttcgctt ggttttcgtc cattcacttc cgcctagctt
    12781 attgatgcga ggcgctttgg cttcagaggc gacatatttt tggatcagat tcagttgagt
    12841 aacaggaata aacagtttgt cgtcgttttg atacaaaata gtcatatagt cttggtgaac
    12901 gccatctact tctagcgttt ccatcccaat gtatttcccg ataccatgat tggcatggac
    12961 aacgtaatct cctgctttta actcattata gcttttcaat cgctctgcgt ttgttactgt
    13021 ttgacgtctc gtttgttttt tcgtcgtttt ttggaaaatt tctttttctg tgatagctac
    13081 tattttttct tgaggaagtt caaaaccagc ctgcaaagct ccttcaacta attgtacctg
    13141 tcctctgatc aatgcatttt tttctgtttc tactactaat atgtcttcat ctcgaagcat
    13201 ttgttctgct ttgcgtattc tgtcctttgt cggaataaag atcacaacag tctgtttttg
    13261 cttgcgccaa cggtccattt ctgttttcag caatggcatt tgtccgaaga actgttgcat
    13321 cgtccgatat tgaaaattat ggattgcttg gaaacgaaga tttcccatcc ctttttggaa
    13381 gagtgagaaa aaggttgtgg tgaacttttc cttctgcacg attttttgta tatctgctga
    13441 aaatgtctgc tcagaaaaca cccgcaattc gctgattttt tgagtctgcc attctgccgc
    13501 ttccctttcg atttcccgat ttgtttccat gattcgctga taatcatcaa cgactagtaa
    13561 actatttgaa gggaaataat ccaagatcgt cacagattct tggtaaagaa gatctgagta
    13621 gaattttgct tcttctgtcg ggacacctgc ttgccagctt gaagtcagct gaccgaagta
    13681 atcttgcaaa aactcgcggt ctgcttcttc tgtggtcgca gcaagccgtt tttctagcat
    13741 tttttgcatt tgctctattc catgttctag atcctctggt ccgtagactt gttcactcgt
    13801 tggggaaacc cagatttctt ccgttttttc gattgagcgt tgtgtttctg cttcaaaata
    13861 ccgcatagaa tctatctcta catcaaatag ttctacacga acaggatagg ttgtcgttaa
    13921 cgggtaaata tcgataatgc ttcctcgaat actgaattct cccggttttg cgaccatctc
    13981 ttctcgtaca tagcccatca aagtcaattg gcgaggaaga ttttccacgt ctatctcatc
    14041 accaatatgc caattcaatt gcgcctgtag ccaagttttc ttattcggca gtcgtttgtg
    14101 caaagatgcg actggcaaca aatagatacc tgcttttttt tcttgaagtg cgttaagcgt
    14161 tgcaactctc tcgcctcgcg cttctggaga agaaaaggcc atttcagcag aaagcacttc
    14221 atccactgga aataaatgga tctgatcttg cggaatcaca tgttgcagat cttctgctaa
    14281 ctgattcgca taatacaaat ttggcatcag aataatcatg tttttatttg ttttcttaaa
    14341 cgctcgagca aatagaagtg ttttcgctga gcccgctaat cctgtgatta gttgtctagg
    14401 cattttttct tctaaattgc tgacccattc ttttacttgc ggatcttttc cgactaattg
    14461 aataatatcc attccttttc ctccttcctc aattgaatcg attcatcgca tccacgaacg
    14521 aatgcccttc tatgagatat tcgactgctt taacagattg acacatgctt tcttctatca
    14581 aaggctgatt ttctttgctg aaaggactaa gcacatgctg gactactgtt tttttccctt
    14641 ctggcctgcc gattcccacc ttgattcgat caaagacatt cgtattcaaa tgggaaataa
    14701 tacttttgat accgttatgc ccgccggcac ttcccttttg acggagccgg atttttccca
    14761 ctgccagatc caaatcatcg tagattacga ctaattcctc tggataaatc ccaaaataag
    14821 tcattagtgg gccgactgca cgaccagatt cattcatgaa tgtttgtggt ttgactaaaa
    14881 ggatcttttc tccattatga aaaaattcgg caacttctgc ttcgaacgga ttttttttga
    14941 aagtagcttg atgctcgcgt gcaattttat ccacgaccat aaagccgata ttgtgttttg
    15001 tatattggta tttggtacct gggtttccta acccgacgat cattttcatt tttgttttcc
    15061 acctaattct aaaaagcagc acaaaaggct ggactgctaa ttagcggtcc agtccatcga
    15121 gcttttttct tttttatact tgtcaatgca tagtataaca caaaacaagg cgtttcggct
    15181 aaaagagaat cgttaataaa tgataaagaa attaaaaatt tcttcaaagt ttaatgaaat
    15241 aattgatata taaaaatagt gaaataacgc acatgtaagc ttttacatat aatacaacct
    15301 tgttatctgt tatattttat agccaaatag cgtgacatgg ggcttgagaa atgttagcat
    15361 aagcatggga aaaaacaaat caatggaagg attgatacta aatgactgca gctgcagaaa
    15421 aaaaagatca tcaaaaagtt attcttgttg gagacggcgc cgtaggttct agctatgcct
    15481 ttgctctagt tactcaaaat atcgctcaag aagtaggtat tgtggatatc aatactgcta
    15541 aaactgaagg agacgcaatt gacttgtctc acgctttggc atttacttca cctaaaaaaa
    15601 tctattctgc tacttacgca gacgcacatg atgctgactt agttgttatt acagctggcg
    15661 caccacaaaa accaggtgaa actcgtttag acttagtaaa caaaaaccta aaaatcaacc
    15721 gcgatgttgt cacacaaatc gttgaatcag gatttaacgg tatcttttta gttgccgcta
    15781 acccagtaga tattttgact tactcaactt ggaaattctc aggtttccct aaagaacgcg
    15841 taatcggttc aggtacctct cttgactcag ctcgtttccg tcaagcactt gcggaattag
    15901 ttgacgttga tgcacgtaac gtccatgctt acatcttagg tgaacacgga gattcagaat
    15961 tcccagtttg gtcacatgca aatgttgccg gcttgcaaat ctatgaatgg gtaaaaaaca
    16021 acccagaaat cgatgaagaa gctatggtta acctattctt tggcgtacgt gacgctgctt
    16081 acacaattat cgagaaaaaa ggcgctactt tctatggtat cgcagtagca ttagcacgta
    16141 tcactcgtgc catcttagat gatgaaaatg ctgttcttcc tttatcagta ttcatgaatg
    16201 gcgaatatgg attgaacgac atctacattg gtgcacctgc tgttatcaac cgtcaaggta
    16261 tccaaaaagt aatcgaaatt cctttaagtg acagcgagca agaccgtatg gctgcttctg
    16321 ctaagcaatt aaaagaaatt ctagatgaag cttttgctaa actagacgct gaataatctt
    16381 tgaacatgac ggaaaacatc tattcggtgt tttccgtttt tttattttat cacccttatg
    16441 gtttctaaat tttttcataa agtagagata accttcgtct tttcctctaa attatgctat
    16501 catgagaccg ttccacccta aacttttact taaggagttg tcgatatgac aagatcttcg
    16561 catcgaaaaa aatcgaaaca tgttgctttg ctttcagttc ttggtgttct cttagtgctg
    16621 atcagctttt atacctatcg cagtacatac tacacaaagc attttttgcc gaatacagaa
    16681 ataaatggaa taaatgtcag caatctaaca gtcgaaaaag caaatgaaaa attaaaagaa
    16741 gcttattctg ataaaaaact ggctattaaa gaagatggaa aagtctggca ggaagtacca
    16801 aaatccgagc tcggctacaa agatgatttc acttcggagc tttctccgat cctaaatgaa
    16861 caaaacggat ggacttgggg aatgacttat gtctcagcgg cagaaaaaca agaaatagat
    16921 cctgtcagtc aaaaccacca aaaactagac actaccgttc agacattgac aactaagctg
    16981 actgatttga acaaagaccg gacacctact actgatgcaa cgatcgaaaa agcaggtgac
    17041 tctttcgtta tcaagcctga agtcaatgga aatacgatcg acgtcgatgc tgcggtcaaa
    17101 caattaaaaa gtgcggtaaa ctctggtaaa gatacaattg aattgactga attcaaagaa
    17161 aaaccaaaag taacatctga agacagctca ctgaaagaac aactcgcatc catgaatgct
    17221 atcgcaaatg taaaagctac ttacagtata aacggtgaga ctttccagat cccatcaagt
    17281 gatattatga gttggctgac ctacaatgat ggaaaagtcg atttagatac agaacaagta
    17341 cgtcaatatg taacagattt aggcacaaag tataacacaa gtacgaatga cacaaaattt
    17401 aaaagtacaa aaagaggaga agttacggtc ccagttggca cttacagttg gacgatccaa
    17461 acagacagtg agacagaagc attgaaaaaa gcgattctgg caggccaaga ttttactcgt
    17521 tcacccattg tgcaaggtgg cacaaccgct gatcatccat tgatcgaaga tacgtatatc
    17581 gaagttgatc tggagaacca gcatatgtgg tattacaaag acggaaaagt ggcccttgaa
    17641 acagatatcg tttccggaaa gccaactaca cctacacctg ctggagtctt ctatgtttgg
    17701 aataaagaag aagatgcaac tttaaaagga acaaatgacg atggaacacc ttacgagagt
    17761 ccggtaaact actggatgcc gattgactgg acaggtgttg gtatccacga ttcagactgg
    17821 caacctgaat acggtggaga cttatggaaa acccgcggtt cacacggctg catcaacacc
    17881 ccaccaagtg taatgaagga attattcggg atggtcgaaa aaggaacgcc tgtattggtc
    17941 ttctaacaaa aataatatat aaaaagaaag cacccgtacg attggtacag gtgctttctt
    18001 tttattatct aacaatgtgc tacttacatt tcagcagcag taaagacttc tgaaacatca
    18061 tcatcgtctt ctagcttatc tactagacgt tccaattgct ctttttgttc ctcatttaaa
    18121 tcaatcgtcg tttgtggaat catcgtcaat tctgcttgcg ccaaagtgaa ctctttttcc
    18181 aactcatctc gtacagcagc aaaatcttct ggtgcagtat aaatctcgaa tacttcagga
    18241 gaagtttgca gatcttctgc ccccgcctct aatacatcct caaacatcgt ctcttcatca
    18301 acagtcaacc catcgcgttc aatagcgata tatcctttgc ggtcaaacaa gtaactgact
    18361 gaacccgttt ctcccagtga tccaccgttt cgagtaaaag ctactcggac atttgtcgct
    18421 gtccgattac ggttatctgt caatgcatgg actaagattc ctactccacc cggaccatat
    18481 ccttcatacg tgatttcatc gtaattcgtt tcatctacgg cactcgtagc ctttttaatc
    18541 gcccgttcca cattgtcgtt aggcatattt gcagcttttg ctttgtccac aacaagccgc
    18601 aaagctggat tcatagatgg atcaggaccg cctgctttag ctgccatata aatttcacga
    18661 gaaagtttct gaaagacttt ccctcgtttt gcatcttggg cattttttct tccttggata
    18721 ttatgccatt tactatgtcc tgacatgatt tttcctccct tgttcttttg agaatacact
    18781 tctattctag tactatttca caaaaaaaca aagccacagc caatctataa acgcttcttg
    18841 aatgccgcaa aaagcacaca taatatcaca gcagtcagag caccgatcga atccaacatg
    18901 acatcttgga acataggtgt tcgtccaccg gtcatcatct gatggaattc gtccaaacct
    18961 gcgtaccctg ttgctgaaag ccaagcaagg atcgctgtca gccaccaaat ttttagcttg
    19021 gggaaaacac ctaaaaacaa gctgcctccc aaaataaaat aggtaccgaa atgtgcgccc
    19081 ttccttaaaa agaactctaa aaatttggcg tagcccagat ggtcgatact caccatactt
    19141 ccaccataat taaaacgtat acccgctaat gtgtctttaa atggctgatt aggcagccag
    19201 ctttctaatc gcgaaacttg tgattgctgt ccgtaagttt gagaagaact gtaaaataag
    19261 attataacga ctatcagtgc gattactaaa taaatatttc cgtttttcat ttgttttttt
    19321 gaagaattca taagtcacct ctgtatttta tcttagactt tttttgaaga aacaacaatc
    19381 attttcatag agacttcttc cataaaaaag tgctatactt aattttgtat tacaatatga
    19441 agggagtttt ttcatgagtt attcattaaa ttggaatcta gattctattt tttccggagg
    19501 cagtcattct gatgctttga accaacggat gaagcaattg gaagaccaaa tgaacgagta
    19561 ttatcaccgc gtaacaaaat ggtcacctag ttctgacaat gcagagcagt taaacgctat
    19621 tcttcaattg caagaaacga ttacgaatgg ttttacccaa tgcagcagct atattactgc
    19681 attgctttct gccaatgtca atgattcaga tgcaaaggtc ttatcaggca agctttacgc
    19741 aatgctgcct cgtctgcaat cagccgaaac tgtattgtca aagaaatttg cagaaatatc
    19801 tgacaatgat tggaatcaga tgctttttca atcttcgttt gaaacaattg cttttcgttt
    19861 aaacgagatt cgtcgtgatg gctcacaatt attatcagaa gctgaagaaa acattataaa
    19921 tacgctttct ttagatggtc taaatgcttg gagcagtcat tatgatacga ttgtagccag
    19981 catttcgatt cccttcgaac aagatggaca agtagtcgaa ttatctgctg gacaagcctt
    20041 caataagatg atgggcgatc cagatccaaa agtcagagaa acacttttcg cagcatggga
    20101 agaagcctgg aaagaaaagg cacccctctt cacggatact ttgaatcatt tagatggttt
    20161 tagactttct gactatgaac ttcatggtgt cacagatttt ctacaaaaac cattagagta
    20221 caatcggttg aagaaagaaa cattgtctgt catgtgggat acaatccaga aaaacaaaca
    20281 accccttgtt aattacttga ctagaaaagc taatcttttc ggtaaagaaa aaatggaatg
    20341 gcaagatcaa gatgcaccta ttattttagg cgatttgaaa gaaaaaacct ttagttttga
    20401 cgaagcagca gcatttatta tcgaaaactt taacaaattc agtccaaaaa tggctaaatt
    20461 tgcccaatct gcttttgaaa agagctggat cgaagcagaa gatcgtcctg ggaaacgtcc
    20521 tggtggttat tgtactgagt taccagaaac aaaagaatca aggatcttta tgacctacag
    20581 taattctgtt aatgaggttg cgacacttgc tcatgaacta ggacatgctt tccatagcag
    20641 cacgatgtgg gatttacctt ctttaaatcg cgaatatgcc atgaatgtcg cagaaacagc
    20701 aagtacattc gcagaactga tcgtagccga tgctacatta aaagtcgcaa aaacaaaaga
    20761 agaaaaaatc aatttgctag atacaaaact gcaaaatgct ttagctatgt tcatgaatat
    20821 ccattcccga ttcatttttg aaaatcgatt ctatgaagca cggcaagaag gattagtctc
    20881 agaagataag atcacagaga tgatggttga ggcgcaaaaa gaaggctatc aaggagcttt
    20941 agctacttac catccatatt tctgggctgc aaaattgcat ttctttattg atgacgtacc
    21001 gttttataac ttcccataca catttggcta cctctttagt ttgggcatct atgcttacgc
    21061 caaccaaaag ggagcaaatt ttgaagaaga atatatccat ttactacgcg atactgcctc
    21121 aatgacgacg gaagatcttg cgaagaaaca tttgaatgtc gatcttaccc aaccagattt
    21181 ttggcaagca ggtatcgaca tggtgactga agatatccaa acgttcatgg aattgacaga
    21241 agaatttatc tgatttctat tttatcacaa taaaaaaaga gttagtccag aatgggctaa
    21301 ct
//
LOCUS       DAZUJR010000051        21068 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.051, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000051 DAZUJR010000000
VERSION     DAZUJR010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21068
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.051"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(184..1491)
                     /locus_tag="ACG804_001799"
     CDS             complement(184..1491)
                     /locus_tag="ACG804_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HFS4832728.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            complement(1494..2075)
                     /locus_tag="ACG804_001800"
     CDS             complement(1494..2075)
                     /locus_tag="ACG804_001800"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HFS4832729.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     regulatory      complement(2191..2288)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(2647..3939)
                     /locus_tag="ACG804_001801"
     CDS             complement(2647..3939)
                     /locus_tag="ACG804_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFS4832730.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     gene            complement(3936..4559)
                     /locus_tag="ACG804_001802"
     CDS             complement(3936..4559)
                     /locus_tag="ACG804_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832731.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            complement(4562..5398)
                     /locus_tag="ACG804_001803"
     CDS             complement(4562..5398)
                     /locus_tag="ACG804_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4832732.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            complement(5415..6302)
                     /locus_tag="ACG804_001804"
     CDS             complement(5415..6302)
                     /locus_tag="ACG804_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4832733.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            complement(6318..7601)
                     /locus_tag="ACG804_001805"
     CDS             complement(6318..7601)
                     /locus_tag="ACG804_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFS4832734.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            complement(8284..8967)
                     /locus_tag="ACG804_001806"
     CDS             complement(8284..8967)
                     /locus_tag="ACG804_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HFS4832735.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            complement(8985..9602)
                     /locus_tag="ACG804_001807"
     CDS             complement(8985..9602)
                     /locus_tag="ACG804_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFS4832736.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            complement(9612..10436)
                     /locus_tag="ACG804_001808"
     CDS             complement(9612..10436)
                     /locus_tag="ACG804_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HFS4832737.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            complement(10429..10989)
                     /locus_tag="ACG804_001809"
     CDS             complement(10429..10989)
                     /locus_tag="ACG804_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832738.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            11163..12119
                     /locus_tag="ACG804_001810"
     CDS             11163..12119
                     /locus_tag="ACG804_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFS4832739.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            complement(12424..13380)
                     /locus_tag="ACG804_001811"
     CDS             complement(12424..13380)
                     /locus_tag="ACG804_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HFS4832740.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            13484..14086
                     /locus_tag="ACG804_001812"
     CDS             13484..14086
                     /locus_tag="ACG804_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFS4832741.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            complement(14174..15673)
                     /locus_tag="ACG804_001813"
     CDS             complement(14174..15673)
                     /locus_tag="ACG804_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HFS4832742.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(15689..16213)
                     /locus_tag="ACG804_001814"
     CDS             complement(15689..16213)
                     /locus_tag="ACG804_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HFS4832743.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            16511..17260
                     /locus_tag="ACG804_001815"
     CDS             16511..17260
                     /locus_tag="ACG804_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFS4832744.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            17251..18036
                     /locus_tag="ACG804_001816"
     CDS             17251..18036
                     /locus_tag="ACG804_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFS4832745.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            18005..18721
                     /locus_tag="ACG804_001817"
     CDS             18005..18721
                     /locus_tag="ACG804_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFS4832746.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(18823..19842)
                     /locus_tag="ACG804_001818"
     CDS             complement(18823..19842)
                     /locus_tag="ACG804_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacid dehydrogenase"
                     /protein_id="HFS4832747.1"
                     /translation="MRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIVSAKDH
                     DAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVPSYSPN
                     AIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRIGLTEA
                     VLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQMINEG
                     FLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSFKPWET
                     IPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNEVSLPK
                     ARQLR"
     gene            complement(19861..20862)
                     /locus_tag="ACG804_001819"
     CDS             complement(19861..20862)
                     /locus_tag="ACG804_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HFS4832748.1"
                     /translation="MTSTVFIILLGFVCRKKGIFSESVGKILSKVVLTVALPALAFRA
                     FMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYKGDKQTTLRVLTIFGSTTFF
                     GTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGLKMEAKNIKAMFVNPIIIAT
                     FAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPWLFQPMDYLAGLSSPLAWLA
                     IGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILAVLTATNILPVNFEALATIV
                     IMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVLTPVWIVVLQMIHGIGLFS"
BASE COUNT         6334 a         4471 c         3663 g         6600 t
ORIGIN      
        1 tgaaattgtt ccttgtgact cggagatgaa cggcaggctc acgacctctt ccttcaacgg
       61 tgttcaatca gctgaccctc ggtattagct caaacaaacg gcaaaatacg aggaactatt
      121 tttccgtttg tttctctaac aatcaggtca aaacgctgat ttcacaacct ttcttttgct
      181 ctattacttc ttgaaggctt cttccaatat ttcttcatct tttttcaatc cattaaagat
      241 caaattcaat atgatagccg taatgctact cattacgatg ccatttccag tgaacatttg
      301 caatgtttgc ggcatttgac tgaataatgt cggcgtaaca ttgaaaccca gcccaaatcc
      361 aacagaaaca gcaacaatca atagattttt atcattgctg aaatcaactt ccaacagcat
      421 acggattcct tggactgcca ccatcccgaa catgactaac attcctccac caagtaccgg
      481 ctcagggatg atttgtgcta acgcaccgat tttagggaat aatcctaaaa caatcaagaa
      541 gaatgcagag aaatagatgg gttttcttgt tttgattccc gaaagttgaa ccaatccgac
      601 attttgagaa aagccagtat aagggaatgt attgaaaata ccgcctaaga taacggcaag
      661 tccttctgca cgatatccct ttttcaattc ttcttctcca acatttttcc cagtaatgtc
      721 accaagtgca aaatatacac ctgttgattc taccatgctg accatggaaa tgatgatcat
      781 tagtaaaatc gaccatacgt cgaaagttgg tttaccaaaa taaaagggtt gtggaacatg
      841 gaacaacggc gcatctccaa tcgcgctcag atcaatcatt cccatgaaag cagctaagat
      901 gcttcctccg actaaaccaa tcaataccgc gattgaacga atgaaccctt ttgccagcat
      961 ttgcacgcct acaattagga gaatcgtcac aaatgcaagt agcagatttg ttttgtcacc
     1021 aaaatcagct gctgttgcat tacctccacc cattttctcg attgctacag gaatcaaagt
     1081 caaaccaata acggtgataa ccgttcctgt tactatagga gggaatagtt ttttaatttt
     1141 agaaaagaca ccagaaacta acacaacaaa gatcccagaa gcgataatag atccgtagat
     1201 agctcctact ccttcattgg ttccgatcaa gatcagtgga gctactgctt ggatcgcaca
     1261 tcctaaaacg acaggcaagc caattccgaa aaatcggtta actgtcaatt gcaataatgt
     1321 cgctaatcca cacataaaga tatcaattga aatcaaataa gtcatctgtt cttgattaaa
     1381 gcctagtcct gtaccgatca aaagaggcac cgctactgct cctgcataca tcgctagcag
     1441 atgctgcagc cctaaaaccg cagcttttcc attttgtgtt tctttttcca cgattatgcg
     1501 tcctcctcaa gaaactcaac ttgtccattc gtcaaggaag caatacgcgc aagagaaacg
     1561 actctcaatc ccatttcttc aagtaactga cgtccatctt ggaaagactt ttcgatgacg
     1621 atcccgattc cttctacttg cgctccagct tgctggcata attcgatcaa tccttttgcc
     1681 gcttgtccgt ttgccaagaa atcgtcgata atcaatactt tgtcttctga agataaaaat
     1741 ttacgagaaa tagaaatcgt acttgtcact tgtttcgtaa aagaataaac agaagctgtc
     1801 aataattctt catccatcgt caaacttttt gcttttctag cgaagatcat tggaacatct
     1861 aattctcttg cagcaaataa agctggtgcg atcccagaag cttcaatggt cacaactttc
     1921 gtgattcctt gttctttaaa tacttctgca aaccgttttc ccatttgttc catcaataca
     1981 gggtctactt ggtgagtgac gaagctgtcg acttttaata cgccctcgcc taatatacgt
     2041 ccgtcttttt gaatacgttc aactaattct ttcactttat ttgctccttt atcatttatt
     2101 aataccgaaa taaccgcttt tgtgcaaaaa cctactatgt ttctgttaaa gaaaaacacc
     2161 ctccacttta tcataagaaa agaagggtga aatagccaat cttttactta tagtccagca
     2221 tttacggtac tggctagaaa ctgtcatcca tattatgacg atatataagt aggtatgtaa
     2281 aactaataat agtgtaaatt cattttcttg caactgtttt gcacgtgaag gcagtttgcc
     2341 atatttgaat aaaaaatgtt gtttcaaata ttgaaaacag tctaacacta ctttctgaaa
     2401 ctgacaacgt ggtttactta tttttttgta aaatctaatg atttttaatg cattattcct
     2461 ttttgttcgg gtttaaatag ttatttttat tttctcctat ctaaaaaagc agcccacata
     2521 aaaagaaggc atgacaaaaa gcatgtcata gccccttttt ccgaataaat agtgttcaaa
     2581 agacagccta tcggcaataa ggcaagattt tataaactac gggaagtaat ttccgtaaat
     2641 ctattcttat tcttttaagc tgacaagctc gtcaatcact actgcttttc ctgaagcaat
     2701 agaatgattt gctgcgattc ctgtcaaaat cgacaaaata ccatctacgt gagttgctgc
     2761 ccgattccac ggatcttctt ctttttcttc accaaataga tcatctaata aacgcggatc
     2821 tcctccgcca tgtccgcccg cttcttgttc gacgattacc tcatatggct caccgaacat
     2881 cggatagaca tggatggact gaagaacggc tgctccttca tcctttttat ctccacctgc
     2941 attgatgtaa gacttttcga tcactttcat ttcgatccgt cctttgctgc cattgaaaga
     3001 aacattgaat ccttcccacg gcatatacgc gtttagcgaa tacgtcaaaa tcgcaccagt
     3061 ttcatatttg accgttacgc ctagtgtatc ttcaatagag atatcatcgg aaaatacact
     3121 gcggtcacga atatatccac tgtctttttc tgcttctaaa tacatttctc gcaattcctc
     3181 attggctgac aggtctatag caaatggatc agctttagct agttcgcttc catagcatcg
     3241 actgtaaaat atttctactc cgcgtttctc cgcattatgc atcccataaa agtttaatcc
     3301 accgaatgca aatacctttt ggggacggct gttcaaccaa aaattcacta gatcaaaatg
     3361 atgggtagat ttatgaacaa gaagcccgcc gctattgtgc ttatttcgat gccatcttct
     3421 gaaataatct gccccgtgtt gcgtatttaa cagccattcg aagtggatag aaaacacatc
     3481 accaatcaca tcactttcta tcagttcctt tatcttcgtg tgatacggtg cataacgata
     3541 attaaaagtg actcgcaggc ttcttcccgt ctgtttttgg accgttatta tttcttgagc
     3601 tttttcctca tcgatagtca gaggtttttc gcaaataaca tcatatcctt ttttcattgc
     3661 acgaatgata taatcatgat gcgttcgatc tactgacgta ataatgactt cagccggccg
     3721 tacgtcatcc agtagttgct caaattgtga tggcatacat gtctttactt ttttctgtcc
     3781 atacttgttc acaagtatcc gatttgcata atccatcctt gtttgagata catcacaaaa
     3841 accgactagt tcacaagttt gatgatacgt agaggcaatt gcctcataaa aaaaacgcgc
     3901 tctcccacca agtccgactt gtacatattt tttcttcatt taaagtcatt ctccttttct
     3961 tttaagcaaa atactgtgac aaatggcagc cctggataca gtaatgcagt gagtaaaaaa
     4021 tcatgctgta tacaccagaa cagtccatac aaaaggcata aataccacag aaaccccttg
     4081 acgttttttg acaacagcca gatattcctt ttgatcaaat aaacaagact atctgcttta
     4141 tcttctttgc agatatcaat tagcgtacta aaaaaactat gggatacaaa aagcaacaga
     4201 cacaatagaa aaggaatcag ataccaagct ccaatctttc ccactaataa ataccaatca
     4261 actgcaaaaa taatgacaaa cagctgaaac aacgtaatga tgaaacacat ccgtttgatt
     4321 tttcctttcc tccaacatac ctttttttct gccaagtaat ggacagatag ataataagaa
     4381 ggatacatca tcaaaaaata aatcagatag acaacacgag cagacagcac taatcctaaa
     4441 gtgaacaaac atcctagaac taaagcgaaa agagcattac tgataagact ggttaaaaaa
     4501 atccgacaga catagtagtt gagcttgtaa agaaacatct cttctattgg ctttttcata
     4561 ttcagccctt cagaccgctt gtactgatcc cctggacaag atatttattg aagaataaga
     4621 aaatcagaaa aaccggtagc agcgacaacg tagacatcgc aaacatactc gcgtaagtcg
     4681 tactagatcc agcgtctgca aataatttga tggcaatcga taccgtgtaa gatctcggct
     4741 tgtttaaata aatcaatggt cccatgaagt cgtcccattt ccaataaaac tggatgatga
     4801 tcgtcgtgat gatcgaaggt ttcagcaaag gaaaaataat tttggtaaag acactatact
     4861 tgctgcatcc gtcaataatc gctgattcat ctaactcttt ggggatgctg accatgaatt
     4921 gcatgatctg gtaaatgaaa aatgcttgtc caaaaaaatg tggtaaaatc agcggcacat
     4981 acgtcccaac caaattcagc cgattgtaaa taataaactg cggaatcaaa atcacttgtg
     5041 caggaatcat catcgttact aacatgacga cgaaccagaa tctttttcct ttgaaatcga
     5101 ttctcgataa tgcgtaagca atacaagtcg agctcagaac tgtccctatc gtcgaaactg
     5161 cagagatgac aaacgaattc ctaaagaaag taaaaaatga aattccagca aaccccgccc
     5221 atccttttgc gtaattttcc cattgaaaag tctctggaat caaattcagc gaaccactca
     5281 taatctcttg atccgtttta aaagaacctg cgatcatcca taagaccgga taaatcatga
     5341 ctagacctaa tagcaaaata aaaccgtatt gaaaccattt cgttactgta ttattcattt
     5401 cttcctcctc tcattcacac aacgacccat ttttttgatg atttgaaaat cagaaaggtg
     5461 acagctccca taatcaacag catgatccac gaaatagcac tagcataccc catagaatta
     5521 aaagaaaaag cttggttata cacataaaga gcataaaagt tcgtggcatc attcggacca
     5581 ccttgggtaa tgataaatgc ctgcgtaaaa gtcataaacg ccgcgattgt ctgcataacc
     5641 aagttataca aaatgatcgg cgaaagaaga ggtaacgtga tcttgtaaaa cgtctgccat
     5701 ttgttcgctc catcgatctc tgccgcttca taatacgagc ctgggatctc tttgatacct
     5761 gcagcaaaga tgatcattgc cgaaccgaat tgccaagcag acatcaaaac aagagggatc
     5821 atgaccagtt tttgatcgct aaaccaggaa agcgcaggtg cgcctaatcg ttccaggaaa
     5881 atattcacta acccgttttt agaaaacaac tcccgccaaa ctagagcgat agaaatactg
     5941 ccaccgatca aactaggcac ataatacaaa gaacgaaaga aagtcgttcc tttgatattc
     6001 ctcgttaaaa gataagcaat caatagacca aagatcagtt tcacaggtac agatgcaaat
     6061 acatagagaa aagtgactcg gatggagttc aaaaaacggg catcactcag catctttata
     6121 taattatcca agccgatcca tgagactgga tttcccaaac gataatcggt gaacgaataa
     6181 taaagtgaca agatcatcgg tatcactgtt atcaatagaa atcctaggat gaatggagaa
     6241 gcaaatacgt aaccgaccac attgtcttga tccaagaacc gttttagttt ttcttttttc
     6301 atgccttcct cctgctgcta tcctagaatg tttgacgcaa actcataaag actctctgct
     6361 gcttcttctg ctgttacttc ttcataaatg actttttcaa ctaaaagatt gtattggtct
     6421 tgaatttccg gattcaaagc actatcaaag acattcactt cgccgttgtc catatcggaa
     6481 atcatttcta aataatcaaa tgtcgcttgc aaagttgcat catctgcacg agcgagctgt
     6541 tctcgaatat tcgacatgat tggtacacca cgttctcctt ttaaaatttc attggcttct
     6601 tcactgtttt gaaagaaatc aataaactta gcagcttctt ctttatgggc tgagcttttt
     6661 gccatactca gcatttgcga agaacgtaaa gggataccag attctccatc tgcttttctg
     6721 cgaggtggat taatcaactg aatctccata tcttcaggag cccctgacaa tatttctgtc
     6781 aactggttac ttgatagaaa caccattgcc gcttctctat ccctaaccgc ctgaaaagac
     6841 agatccgtcg tacttgcagc tccaccacct ggttctggat gggccccttt gtctaccaga
     6901 tttttacgca gctggaaaaa atctgttaga tagtctggat tttcaaatcc caagctgtta
     6961 gatagatctt cccgattata aaaattcaat cctttctcaa cttgtggtat ttgaataata
     7021 cagccagcta taaaatcttc gaatcttgaa atagcataga ttcctaattc ttcagtgatt
     7081 tgatagctga tttgttcaaa ttcatcccat gtccaatttg aagctggttc agggatattt
     7141 aattgttcaa atatattttt attgtaagca atcgcaaacg aattcacccc gttagacagt
     7201 ccaactaatt gcccgtcgta agtcgtcgtt gctaaatagg attcatctgc attagaaata
     7261 tcaattatcc cttgctccac atattcatct aatggttcaa tctgattgat gtattgagga
     7321 aattgattgt tcagttggaa aatgtcccag atatcatctg atgctgctag tgtacctaat
     7381 tttgtgtaat atccttcata atcataaaat tcataatcga tcgtcacatg gggatttttt
     7441 tcttcataaa gctcgattac ttttactgtt gcatcgtgtc ggacttgcga accccaccaa
     7501 gccatgttca gcgtgatttt tttgtcatct tcttgcccac aagccgtcaa gaagaataac
     7561 ataacactta aagctaagat gattctcatt cttttcttca ttctctgcac ctctacttcc
     7621 attgttattt ttcaatatac tgtattttta tacagaacat atttattaaa cgatcttttt
     7681 caaggggaat aaaaaccaag acttgcctta tcgttctgcc taggatgaac aactcaatac
     7741 tttcaagaaa aattagatag tgctgattct tctttcatcg ctaaaaacac ttcttgcttc
     7801 aatgatggga ggataattac gcaaagaaaa aaggatatca gacaactgcc caatatcctt
     7861 gacatagcta aataagcatg cttcttcgtg tgcgctcttc cctaaaaaac agaaaaataa
     7921 ctagtaattc tgtatgaaat taggtacaat atacacgtcg atgcacaagc attgactatg
     7981 gcaacttgat tggtcagttc ccgctgactt ttcaagcccc gacaatttag ctgctactaa
     8041 attgtcgggt gcctttttta gtttttattc gtttttcatt ctatagaaag cgcttcaata
     8101 aatcaagaca tttttttgtt agaatgctaa taataacaaa aggttttaac tcttcttatg
     8161 tacattacag gtaaaaaaac aaaaaaattt ctcttttttt tgaattctga acaaatagta
     8221 ctggagtaca aaagacgagg aagagccact atctgctctt cctcgtcttt tgattctcac
     8281 ctgttattca tgattctttt tctcagtttc ccgatatttt tccattttac gactaaaaag
     8341 ctctccgcta cttggtggcg tatatgtgat ggcatttgct cctgcttgaa tggtctcagc
     8401 aatactttct tccgttggac cacctgtcgc aatgatagga agttcaggat attttttacg
     8461 aaaatggcgt actgcttctg cagtttcttt acctgcactg atattgataa tcgaaatacc
     8521 agctgctaac ttttcatcta tttctgtata tttcgacgtt accgtactga taactggaat
     8581 atcaactact cgacaaactt cttttactgt ctctaaaggc gtaggaccgt tcaaaacgac
     8641 ccctaacgaa ccttgcgctt ctgcgaacat gctcatgtag gaagaacgag caccttgtgt
     8701 caaaccacca cctacaccgg agaaaactgg aatgtcagct gcctcaataa tgcttttagt
     8761 aatcgctgga tgaggtgtaa aaggatacac agcaattact gcattcgcat ttgtattacg
     8821 tatgatcgca atatccgtag taaagatgat cgaacggatc aattttccaa atatcttgat
     8881 cccgcttgct tctaaaatga tttccggtac tcttacgata tcttttctca attccgtcat
     8941 gatttctggc gtaaattgtt ctgccatcag ccacttctcc tttgctatct ccggtcatac
     9001 tgattcaatt gatacgtctc gatgacctgg atgatttttt gcgcataacc ggggtctgtc
     9061 gcataacctg catcttgcaa tgcttgtgcg gcttcctgat agttggtggc cgtaatcact
     9121 ttttcataca gcgcaggatt ccaatctact ccttggacga acagttgtgt atggtcatcc
     9181 atggactgtt cccatgaatc atacactttg aagtctcctt ggatagttat ccattcttcg
     9241 ttaacaaatt cctttgtttc caggcttact ttcttctgat ccccataagc cttgatcccg
     9301 aaaagattat tgtatttgct agccaaggta ctttttcccc aatttgattc taatatagct
     9361 tgtcctaaaa tgatactagg aagcactcca taaccatctt gtagttcttg ggcatgcgga
     9421 acaagccgtt caataaattg ctgatgggat tgcgcttcat tttcttgctg attatcagta
     9481 aaaggagaag acagattctt caaggaaaaa acaaaggcta agagtatcac tgctacaccg
     9541 gcaaccactg ctggccaacg gatattcttg cgcttttgct ttttccactt ttttttcgcc
     9601 atgatcaatt cctacttttc atttaattca ttcagatatt cttctagcgt caattggtgt
     9661 ttggtgatat actcagcgtt ttctttaccg acataacgta agtgccaagg ttcatatgtg
     9721 atcttagtta tatcttcgtg tccttttgga taacgaacga taaatccata ctgcgcagca
     9781 ttatctgcga tccatttagc tccaggctga tctccgtaac ttgcatccaa tacagtagaa
     9841 ggataactgt tgtaccagtt ttgatcgacg acatcgactg ccagacctgt gtggtgttcg
     9901 ctgtatcctg gctccgtaat cgtttcttta gtaatctttg tcgcctcctc ttctgataca
     9961 ccttgacgac tcatcacatc ttggacattt tgttcgaaaa cttgttgttg ggatgataca
    10021 gaccggtaag ctgagaccat cactaatgga aatccagctg cttcagcagc cttggcaaat
    10081 gcttcatatt ctggagcaat gcgtttgtcg atcaagtatc cgttacttaa tgatgccaat
    10141 tgagtagact catcaatttc tttttctaat ttgtgatctg gaccaaccaa aactagcttc
    10201 caatcgtctg ttttaacatc tggcaattgt ttggacgtac gatcttttgt ttctttgtcc
    10261 tttaccttgc tgctggttgt ttgactgttc ttttctttac tagcagttgt tttggtgctt
    10321 gttcgttcga ctgcttgatt gccggcttga acatgcgaat catcatcgct aaaaataaca
    10381 tagcccattg ctgcgatcat aatcacaact gctccaaatc ctaaaaattt attcacttga
    10441 aaaatccttt cgttgttctt cacgttcccc attcgcctca tgaacgtaag tttcttccag
    10501 attttcattc acccaatcga gaagttcgat tttttctcct tcgatctgtt tttgaacatc
    10561 tgctggcaga cgaaaattca aaatatcatc atagccccat tcatcatatt gaatacttac
    10621 tttcaagtca aggtatctac cagcctgctg attatttttc aaagggatca gctcgacttt
    10681 tgctgctttg ctgctaagcc atttttgcgc gatgcgtgtt ttgatttgct tgtactctgc
    10741 aacggcaacg tttcgttttt cgggaaaaat aatcgtttga cgcaaaatct tttgcgttag
    10801 catccattca taatcagtga aaagattttt tactttctgc atcgcttcag atggcagatt
    10861 tttctcgcca tctttccatt tttgccattg ttctggactg atcagcaagt attcatctaa
    10921 aaaatttttt tcagtttcaa actgttctaa taatacactc ataataagat caatatatac
    10981 ttgatgcacg tttatcccct ccttttaact attctactta agttttgatc aaaaagcacc
    11041 tcttaaatcg ctgctttcat tttttttaat gtttcaagtc ctctcctctt tattcttcgt
    11101 gatttttgtt ataataatag acagacaaga aactcaatcc aactatgaag gagcgttttc
    11161 agatgaaaaa atatcaatgg ggaatcgttg gtcttggtac catcgcacat gagtttgccg
    11221 aaagcttcaa tcaagagacg agcgaactaa cagcagttgc ttccagaact tcagaaaaag
    11281 cggaaaactt cgctcaccgt tacaatattc caaaagctta cggaagctat caagaaatgt
    11341 tagacgatgc tgaaatcgac atcgtgtaca ttgctgtacc aaatagacag catatcgacc
    11401 atatcttggc agcattggaa gcaggcaaac acgttctatg tgaaaaagcc atcacgatga
    11461 ataaaaaaga actggctgac gctatgcgct tagcagaaga aaagaatttg atcttagcag
    11521 aagcgatgac aatcttcaac atgccacttt atcagcagtt acgctcaata atggatacag
    11581 gaaaactggg ggctttaaaa atgatccaag cacctttcgg cagttacaaa gaaccagacc
    11641 ctaaaaaccg gttcttcaat ccagaattag ctggaggagc tctgttggat atcggtacgt
    11701 atgctgtatc tttcgctcgt ttctttttga gctctcaacc tgaagtagtt gcctctacaa
    11761 tggttccttt tgaaacaggc gtggacgaac aatccgtcac tatcttgcgt aacaaagaaa
    11821 atgaacttgc tgctgtcagc ttgacttttc aggcaaaaat gccaaaagtc ggtatcgttg
    11881 cctttgagaa cggttatgtg acgattgctg attacccgcg tgctgatcgt gcggagatct
    11941 tatttacaga tggtacaaag gaattcatcg aaagcgggaa tacatctgaa gcaatgaatt
    12001 acgaaataaa gaatatggta cacatgattg aaggtgactt gcccaatcgc tctctcttct
    12061 tgacaaaaga tgtcatcgaa atcttggatc aaatgcaagt tctatggaaa aatatgtaat
    12121 tttaaaaggt tgtgaaaaag ctgttctgca tcaagtaata agaacagcca aacaaaaata
    12181 gctcctccta tttttcgttt ggctggactt attaccgcag aggaaagctt ttgaacaccg
    12241 tttaagaaag aggttgtgag cctaccgttc agctccgagt cacaaggagc aatttcaaaa
    12301 aacagcttct catgtttgtt gaatattgtg acttgtgacc gaggagttga caggagaaca
    12361 ccgtttaaag aagaggttgt gaaatcagct ttttgacctg aatattagct gaattcacaa
    12421 cctctatttt tggatttttt gttgggagaa ttctgccttg atttcaataa aacttttaaa
    12481 agactgcaaa aactggaaca attctgctcg atcctcgaat tcagggcgac tagtcggcag
    12541 aggcatttgc cgatacaata cataaacttc ttcaatacgt gttaaaattt gtctgccatc
    12601 atttgactct gaaaatgttt ctgcagtata aatcaataaa ccatagatat gttttccata
    12661 ataagctggt tgctggattc tctctagatt ttccagcatg tctttaatca cattggcctg
    12721 tgctcttctc atagagaagt aagtttcgta gtatagcggc tgtctgagcc agtagttttc
    12781 ttgatgttct ctggcatctt cttggctttc gcgaatgaat gtcagtaaat gttcgcattt
    12841 gatctgcaca tcttctttat tttctgataa aagaaattct gccatttgtc tcaaaatatt
    12901 tcgaaattct ttttcgatct gtatttggtt ttccttcagc tgcttcgtac gatctggcat
    12961 gtaaacattt gcaagcaaag caaatactaa tccaatcgcc attaatcccg cttcattgcc
    13021 gatcagctgc caagacatgt tttcctccac taaataatga gtgaccaaaa ccgaatttac
    13081 tactatccct tcggttaatt tgaagcgaga ggcaagcggg atgaacagga ataaaaaaag
    13141 actgaagcca aaaatagtat acccaacagc aaaaaaactg aacagtgctg ttgccgtagc
    13201 taatataaag gctgcgattc gattcatgcc cgtacgcaat gtagagcgct tggtatttcc
    13261 tacacttaat aatgcaatga tccctgcagc tggccaatac aacagcgata agctacccgc
    13321 tgtgaccatc gaaaagaaga cactgatcac tgttttgact gttcgcattc ctatacgcat
    13381 ttacttcccc cttttttatt ttaattatac ttgaataatg aaaaactagc tatcagacaa
    13441 aagtttaggt atgatagtaa aaagaccaaa aaggagaatc tctatgcaat ttggccgttt
    13501 tcgactaggt atgcgtacga tcaaaagtgc cttagctgtt tttttatgta tcttgttttt
    13561 tcatttgact caacgaggaa tcccgatgat tgctgcatta tctgctgttt tttctttgcg
    13621 tcaggacttg actacaaccg tttcttttgg aaagtctagg atcatcggca atacattagg
    13681 tggtacatta gctatcattt atttttttgt caaaagctat tttcacaatg attttttggt
    13741 agaattgatc ttgcttccta ttctagttat tattgtgatc gtcgtgtcag atggtattaa
    13801 caataattcc ggtatcattt ccgcaatagc tacgttgttg ctgattgcgt tgagcatccc
    13861 tcaaggcgaa tccgctttgt atgctatcca acgtgtacta gatactttta tagggacatt
    13921 cattgcaatc ggtatcaatt tctttcttcg tcctcctgaa acagaaaaga aggaagaact
    13981 atcagaagat ttggtcgaac tccaaaagaa agaacgattg ctaagaacaa atttacaaga
    14041 gatagaagct aagatccaaa aacaaaagaa aaatagcgag gactaatttt cttttgcaat
    14101 aaaataaaaa aatggagaga agaactttaa aaagtcttcc tccatttttg attgaacggt
    14161 gaagtgtact actttattct tccttcatcg agttttgttc tgcctctttt ggcgcttcat
    14221 acatatttac ttggctagta gtcccacgtg tcgacaaatt ctctacgatt tccttcaagt
    14281 caagtcctgt tgtcgctttt agtgtttctt gagtagaaga aagcaaattt gtggcataat
    14341 ttgtcactcg gttcgctcca ctggtttctc ctgaactgct tcctgtatcg acaacagaga
    14401 ttttttcgat atttcctagc ggctgtgctg cttcgcgcat caattgcggt agcatatcga
    14461 taaccatact caagacagct gcttcgccat attccttgaa ggcattggcg atcttttgtt
    14521 ttgcttcggc ttctgctttt ccttttgcta gtgctgcttc ggcttctgct tgtccagcta
    14581 aacgtgtctt attggcttcc gcttctgcca gtgcttccac acggaatcgt tctgcttcgg
    14641 cttcagtcac ttctttgact ttttgagctt gtgcttcttg ttctttagcg taccgatcgg
    14701 catctgcttt tttcttcact tccgaatcat attgcttttc acgacgtgtg atttcttttt
    14761 cttccagttc gatttgtttt tgacgttcta cgattttaat ctgcatttcc tgttcgatta
    14821 cttgttgttg tgctcgggca ctttctaaat tgtaggcttg gtctgctttt gctttagcaa
    14881 catcttgttc ttgtttgtag gttgctaatt tcagttcttt ttcttttaat gattctgcga
    14941 tctctgtttg tcgctgtaat tcagctgctt gtgattcttt ttctgcttga gcttttttga
    15001 tacgcgtttc ttttagagct tccgcttctg ctatatctgc atctcttttg acttgggcga
    15061 ttcttggttt ccctaaagag tcaagataac cgtttttgtc tctgacctct ttgatagtga
    15121 aagaaacgat gatcaacccc atttttgcaa ggtctacaga agcgacttct tgtacgcttt
    15181 gactgaactt atcgcgattt tgatagattt cttctacagt catagaacca agaatcgagc
    15241 gcaagtgtcc ttctaatact tctcttgctt cattttccag ttcttctctt gtcttgccta
    15301 aaaactgttc tgctgctgta gcaatctctt ctacagatga accgattttg atgatcgaag
    15361 taccatcaca catcaccggt acgccttgtt ccgtatacac ttcaggggtg gagacgtcca
    15421 atttactcga taatagactg atccgattcg aacgttgaaa aactggcaag acgaatgcgc
    15481 cacctccacg cacaattttg attttgttat tgctttcatc aatgtgcaca tttttgcttc
    15541 ctaaataact tccactgatg atcaacgctt catccggttt tgctgtctgg tacttcgcta
    15601 caaagacgat cagcaacatc agtaaaatca aagctgcgat tgcgatcgcg ataaaaacaa
    15661 ctggtatttc catttaacac acgctccttt aagcttttat catgctttca taaggcatga
    15721 cataacagat tctttccttg atctcaatga tcaatacttt cgttccccgc tcagctgtct
    15781 gttcttgggg gctgtaaaaa caagctggac gactaatgga accggtaaca cttttcaact
    15841 gaatttctcc catacctcgt acagggatcg gtgtgatcac aacagctact tgtccttcca
    15901 gagttttttc agaagacgac atcgttgatt cggcatgttt catcggcatc aatatataga
    15961 aattaagcaa aaataccaac actatcgata tgcctccact agcaataaat aaaaataaag
    16021 atgattgatc tgttaaacgc tcacctagaa aaccaaataa gcttgtgaaa gttaaccaag
    16081 ggataataag catcggatca agcgggccat caaaatcgaa tacatctcca aaaataatca
    16141 ataggactgc caatcctgca caaatcagca atgtatacca ataaatcgtc tcaagtgcga
    16201 ttccccctat catatacacg cctccttcca tttctacgtc tatcatacca atgtttgaaa
    16261 attctgtata gcttctttta ccgactcagt ggtgtttttt ataggaaggt tgtgtttatc
    16321 gttgacaatt tgttaaattt ttgttttcat gttaaaattt tcacaataaa ttctttcgag
    16381 gtagcctatg tttccttttt ttaagaaaaa accattaaag ctccagaaca cgatcatcct
    16441 tgtcgtttgt ttctccacat tcgtttcttt gattgtttct gccatattga tcaggaattt
    16501 tattctttcg atgaaccgat ctagtgtgtc agataaaatc tctagcattg ctaaaatcgt
    16561 tgccaatgat aaactcatcc aaaaaaagct gcagactggt gacccgacac atgcgattca
    16621 aggaataaca aatgaaatca tgattgcatc gaatttagat tttatcgttg tcatggaccc
    16681 tgaaggcatt cgatattctc acgcagaccc aagttacatc ggtcttcctt tctcaagtca
    16741 tgaagatgtg aaaaaagtga ttggaggaca agaatttttc tctgaaaaag aaggaatgtt
    16801 agggttcggc ttccgctatt tcgtccctat ttattatgat caagagatta ttggtgcagt
    16861 ttgtgttggc ttaacaaaca acacgattga caatcaagtc aaagatggac aaaaaatgat
    16921 tgttttttca ttgattattg gacttagcgt aggcatcata ggcgccgttt ttcttgccca
    16981 aaaaatgaaa aaagtactgc ttggacttga accacaagaa atagcagaac agttaagtga
    17041 aaaaacgatt atcgaaaatg aagtagatga aggaatctta gccatctctt ctgataaaac
    17101 tatcctcttg atcaatacac ctgcaaaaaa cattttctac caaacagagc agctattgga
    17161 tttcgaagta ggaaaaaaat cagtgataat ctatatgacg ttttgtttaa agagacgatt
    17221 gagcatcaaa cgaccgttcg gactcaatcc atgtatttaa atgggataga aactatttct
    17281 agcgttacac ctctttttag caatgaccgt tttttaggag cagtcgcaac tttacgaaat
    17341 cgatcagaag taatgaaatt aatggaggag cttgggggga cgaaacaata tataaactcc
    17401 atgagagctc aaacccatga attcatgaat aaacttcatg tcatttctgg tttgattgat
    17461 ttgaagaagt atgaagaagt cacccatttt atccagcagc taaatcaaaa ttataaaaaa
    17521 gagattggcc aagtctcaag tctgatcaaa gtacctgcaa ttgccggttt tttattaggc
    17581 aaaataaacg aagccaaaga acaatctgtt gaaatgctgt tagaaagcga ttcttttatc
    17641 cctaaaatgg agatggatga ctccatccat tcacttttgc aagtgttagg gaacttactt
    17701 gataatgcaa aagaagccgt gctacaaaaa catgaaagaa acggacaggt ccggattcat
    17761 ttaaactatg acacagaagc tgaagtattc atcgtgaccg tctgcgatga cggtgtcggg
    17821 atatcagaag aaatctcaga aaaaatattt acgctaggtt tttcgacgaa gggaatcaat
    17881 cgtgggtttg gattgaatct catccattca atcgtcaaac gccacggtgg atttttagaa
    17941 ttttccaaac aaacaaatgg cggtacaatc gtctatctag aattaccaaa aaaggaagat
    18001 caaaatgatg acaaatgtcc tgataatcga agatgatcca atggttgcag aattgaatcg
    18061 tacttttgtg gaaagcatcc ctaatatgaa cgtaatcgaa agtttcagaa atgtagaaga
    18121 aggaaaaaaa tatttcagac aaaaaaacgc agatctgctg ctgcttgatg tatacatgcc
    18181 tggcgaaagt ggtatccatt ttttatcttg gcttagacag caaggaaatg atatcccagt
    18241 gattttgatc actgctgcag atgatatcga aaccataaag aatgtgatcc gctacggtgc
    18301 cttagattat ttgatcaaac cgttcacttt gcaacgtttt cagctggcga tcgaaaagta
    18361 tcttgctttc tctcagacaa tccaaacgac tgaaaaagcc gatcagaaat tgatcgatca
    18421 agtattcaac cacaccactc ccattcacga aataccatca ttcatcgatt tgcctaaagg
    18481 tctgtcaaaa ctgactttaa aaaaaataag tgcatttatt ctaaaagaag atactatttt
    18541 ttcaacaaaa gaactggctc aaaaaagctc actgtcacgt atatccgtca agaaatattt
    18601 gaatttttta gtagaacaag atatattgaa cgaaagaatc aaatatttgg aaatcggccg
    18661 gccgctaacc tgttatgaat tgacaaagaa tgggcggaaa aagctcacag attactgttg
    18721 agtcatcgaa ttatcccata caaaatagtc caagtataca gaagtaacaa ctgtttactt
    18781 ggactatttt taaacatttt attgacgaat atccatgttt tcttatctta attgacgggc
    18841 tttaggaaga gatacctcat ttttcgtttt tccagtttct attatttcac gaaagttctc
    18901 gaaacttgtc gaaatcatat ttgataatgc ctcatctgta tttgaaccta catgcggggt
    18961 tacaagaact ctagggtaca tttctactaa ttgctggata gcagggtctg gaatcgtctc
    19021 ccatggcttg aaggatcgga aaaaaacctc tgtttcattt gcaaaaacat cggttgcaaa
    19081 accagctaaa tgattgcttt tcaaagctct taaaatagct tcattatctt gaagctctcc
    19141 acgggctgta ttaatcaaga tgctaccttt tttcatttga gctaaaaatc cttcattgat
    19201 catttgatcg ttttcacctg ggatatgagg tacatgaata ctgacaatat cgcttttggc
    19261 taataactct tcaagcgagt ggaacgtcaa tactttttta gcagcttctg tctgatgaat
    19321 atcgtagccg atcactttgg ctcctagtcc cttaaacaaa acagcttccg tcaaccctat
    19381 cctgcctgtt cctatgatcc ctactgtgca atttctgatt tcacgactaa acatttgctc
    19441 atccactcga aaatctttga aagatgttcg gatcgtcgta tacgcagtat ttctcaaaag
    19501 catcatggca aaagtcaaag ataactctgc tatcgcattt ggcgaatacg atggtacacg
    19561 ggctactgtc ataccaaaat cagctgccgc ttgtagatcg atatgattga ctcccacagt
    19621 ccgtgtaaaa acataacgaa tcccatattc ctgcattttt gcaagattgg tctcatctgc
    19681 tatacaattt cccctcaaca atacagcatc atggtccttt gctgacacga tattgtcatg
    19741 tgtcaacagt tcttcataaa gactgagatc ataatggtaa atattcaatt tttcaaaaaa
    19801 atctatctcg ttcggacgaa caccgtaaca tgcgattctc atactttctt cctccatttc
    19861 ttatgaaaat aaacctatgc catgaatcat ttgtaataca acgatccata caggtgtcag
    19921 taccacagca aaaatagttg acagtaagga tgcattggag gctaaaagtg cctccctatc
    19981 aaaactgata gcataggctg ctgccactgt tgcagctggt gtagccatca tgataacgat
    20041 tgttgccagt gcttcaaaat tgactggtag aatattcgtt gccgtcaaaa ctgctagaat
    20101 cacgatattc aatgcaggta caaataccac tttgactaga ctgtaatacc atgaagtttt
    20161 ttcagatgca gcttttttga agcttacttc acctaatgtt gcgccgattg ctagccacgc
    20221 caatggtgaa cttaaaccag ctaaataatc catcggctga aatagccacg gtgcagtctg
    20281 gtcaattcgc aaaaacgcta cttggcttat ctctccttct gcacctgtaa ctgacacttg
    20341 tggcagatac ccttggaaca gccaaatgaa aaggccggca aaagtagcga taatgattgg
    20401 attgacgaac atcgctttga tatttttagc ttccatcttc aagccactca tttttatgta
    20461 tccataagaa tacaaaaaga ttcggtagcc aatattgaaa attgaggaat acatcacgcc
    20521 gacaggacca taaatcgcac tgacgatagg cgttccgaaa aaggtcgtag aaccaaagat
    20581 cgtcaggaca cgcaacgttg tttgcttatc ccctttatag cttaagaaaa aaggttttga
    20641 aactagaata agaataatat aaataactaa tccccaaatc aagacattga ttccttgcat
    20701 cagtaattct gtattgatat cttgcatgaa agctcgaaat gccagtgctg gcaaagccac
    20761 tgttaagacg actttcgata gaatttttcc aacagattca gaaaaaatcc ccttttttct
    20821 acaaacaaac cctaataata taataaaaac tgttgaagtg attgcactga caatcgacat
    20881 atctgtcaaa gtcgatcgaa aaatgtcaaa taagttcatc tttctcctcc taattatgtt
    20941 catttattca caataaaaaa agcttttatt ttgctaatac gtattaacat ttttaatttt
    21001 atctttacat tgttacttat tgaacaatag gaaattaaag aaacttttga aacttatgta
    21061 aagtgatt
//
LOCUS       DAZUJR010000052        20399 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.052, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000052 DAZUJR010000000
VERSION     DAZUJR010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20399)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20399)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20399
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.052"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(387..1853)
                     /locus_tag="ACG804_001820"
     CDS             complement(387..1853)
                     /locus_tag="ACG804_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFS4832749.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            complement(2144..4228)
                     /locus_tag="ACG804_001821"
     CDS             complement(2144..4228)
                     /locus_tag="ACG804_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFS4832750.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQETKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKKFMQYIASAEQFSTHPIAQSVLEGYAGPLLP
                     TTNIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPLSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKQAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKKEDE"
     gene            complement(4370..4492)
                     /locus_tag="ACG804_001822"
     CDS             complement(4370..4492)
                     /locus_tag="ACG804_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832751.1"
                     /translation="MNLDKLPATGFKLSCYPVKIKKASAGWIRAGAMIEEKKKE"
     gene            complement(4753..5112)
                     /locus_tag="ACG804_001823"
     CDS             complement(4753..5112)
                     /locus_tag="ACG804_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HFS4832752.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(5142..5483)
                     /locus_tag="ACG804_001824"
     CDS             complement(5142..5483)
                     /locus_tag="ACG804_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832753.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERVDQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSIFAQF"
     gene            complement(5480..6154)
                     /locus_tag="ACG804_001825"
     CDS             complement(5480..6154)
                     /locus_tag="ACG804_001825"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFS4832754.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     KFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTAEICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            complement(7330..8628)
                     /gene="asnS"
                     /locus_tag="ACG804_001826"
     CDS             complement(7330..8628)
                     /gene="asnS"
                     /locus_tag="ACG804_001826"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HFS4832755.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(8668..9858)
                     /locus_tag="ACG804_001827"
     CDS             complement(8668..9858)
                     /locus_tag="ACG804_001827"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFS4832756.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(9879..10406)
                     /locus_tag="ACG804_001828"
     CDS             complement(9879..10406)
                     /locus_tag="ACG804_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HFS4832757.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEETDHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(10453..13242)
                     /locus_tag="ACG804_001829"
     CDS             complement(10453..13242)
                     /locus_tag="ACG804_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase C-terminal domain-containing protein"
                     /protein_id="HFS4832758.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLVQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(13389..13589)
                     /locus_tag="ACG804_001830"
     CDS             complement(13389..13589)
                     /locus_tag="ACG804_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFS4832759.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(14042..14362)
                     /locus_tag="ACG804_001831"
     CDS             complement(14042..14362)
                     /locus_tag="ACG804_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832760.1"
                     /translation="MKKRLLWCLLSLSLSLTSQPVFAEETQRFPITGTRLYKNVYVQT
                     PDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(14865..15983)
                     /locus_tag="ACG804_001832"
     CDS             complement(14865..15983)
                     /locus_tag="ACG804_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832761.1"
                     /translation="MAKKDKELLSQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            16216..16338
                     /locus_tag="ACG804_001833"
     CDS             16216..16338
                     /locus_tag="ACG804_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832762.1"
                     /translation="MHLIMIFSLLSIISLFAFSASRLLDAETQPIPVKVRKNDR"
     gene            16454..17761
                     /locus_tag="ACG804_001834"
     CDS             16454..17761
                     /locus_tag="ACG804_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008800 - beta-lactamase activity
                     [Evidence IEA];
                     GO_process: GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HFS4832763.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSVT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETARLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAE
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            17882..19081
                     /locus_tag="ACG804_001835"
     CDS             17882..19081
                     /locus_tag="ACG804_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HFS4832764.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYSSTWTFAVI
                     LTYFVVLEIFYSTFYFLIPLVFFSIFAFSYFSEKRRLLNGLLFNIFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVFLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCIPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYWAQSRATLNPPILLMSGGQGADEKVPE
                     AMAMKQYAMEQGIPERDILVETNSTTTLENMRYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(19108..20376)
                     /locus_tag="ACG804_001836"
     CDS             complement(19108..20376)
                     /locus_tag="ACG804_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HFS4832765.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVRKGILFLPIVKRMKEKNKV"
BASE COUNT         5905 a         4344 c         3559 g         6591 t
ORIGIN      
        1 aataaatggt gttcaatcag ctgaccttca gcattagctc aaaaagcggc aaaatatgag
       61 gagctatttt tccgtttgtt tctctaatac tcaggtcaaa tcgctgattt tacaacctct
      121 tccttaaacg gtgttccaaa gcttgcatct gcggtaataa gcccagccaa acgaaaaata
      181 tgaggggcta tttttgtttg gctgttctta ttacttgatg caggacagct ttttcacaac
      241 ctctgattca cggtgttcca gaagtagctt cttcgaaaaa caagccgaaa cttcacaaaa
      301 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
      361 aacctcttgt aacaagtatt tctattttaa ggctgaacca ctgtttctgg ttcagtgatt
      421 tctttgtttt tgtctcgacg agcaattgct ggcaagatca tacctaataa gatcaagacg
      481 attggtgtga tgatattcgt aaataattgg aaccaccatg ctttaggatc agcagtataa
      541 tctacttttg gcaccattcc taggatacat gcaaacgcag tgaaggcaaa gcaccaagca
      601 ccaaagataa aaccgatttt tggattttta acaaatttat attcagaatt gaatttctta
      661 taagctttat tcaacatcat atatgccaag aacacccata ggtaacgcat tggcatgaca
      721 actgagttca agttcgtcaa ccattttact aattcattca tatctttgat accaaaaatc
      781 ggcaacaaaa taatgattcc tactagtata cctgtcagaa gataaccatt caccaatgta
      841 cctttacgat tacgtttacg tagccagttt ggtacaaatt ctggatccgc atctgctaac
      901 aagattttta gtggtgcatc aattgaaaag gctaatgcgg agatttgtcc aatcatgttt
      961 gtcaatgcgt aaatgatcat caatgagtta ccgataccat agtaattacc taaaatttga
     1021 aaagcactgt atgccccatt tgccatcaag tctttaggaa tattatcact agcaaacagc
     1081 atacccattg cgactgagcc taatacagca caaatcccta ccattgctgc taagaagatc
     1141 atccctttag gaaattcctt tgcaggattt cttgtagagt tgacataagg ggatattttt
     1201 tccgcccctc caactgcaaa tactagcatc gaaacggttg tgaaataact gaaatcaaat
     1261 gttggaatat atgttttcac ttgattcata tgtggtgtgg caaattccat cgttggattg
     1321 atgaacggtg ccgttacagc taaaagaata aataagatcg acatgacgaa catcgctgtt
     1381 ccggccagtc cgccaatcac tttcaaagta gaaagtcctt ttgttgataa atataaaaag
     1441 gcaagaaata taataagtga aataactgct accatttgta ctgacatcgt atttacgata
     1501 tttccatttc cttggactgc ccaaccacca gcaatcagaa ttgcttgagg cttttgtgcc
     1561 aaataaggaa tatggacgac ccagtaagtc caagcggcat agtatgccag tcgtttatta
     1621 gatgtcgtat tttcgaccca tgaactgacg cctcctttac tatccttgaa ggctgatcct
     1681 aattgtccaa cgatcaatgc gtatggaata aaataaatgg ccaaaatcaa tagccaagag
     1741 gtgacaactg atactccttg ctgagcatag ttattaacta cattccccat gccccaaacc
     1801 atgttaaatg caattaacgc aacagtaaac cagcgtaatt gtttgttgtt cattcgttct
     1861 ctcctttatg ataaaaattt gttatccaga tgtaatcata ttcaattttt aacaaactta
     1921 caagacagtg ttattttatg tgtgtattct tttatttaat acacatcgtt ttttcatatt
     1981 ttttccatca aaaaaataag ttattttctt ttatttcatt gaccttattg aatttcaagc
     2041 tattttgaat tttctgcaaa attaaaaaca ttagttattt tataatccta tctattttct
     2101 ttacattttt cattaagaaa aggatataaa aaaaagagga cgttcattcg tcctcttttt
     2161 ttacatgcaa gcttcgcatg gcattcaaaa cagctaatac tgtcacccca acatctgcaa
     2221 atactgcatc tcccattgat gcaaaaccaa aagcacctaa ggcaagtacc aaaattttta
     2281 tcccaatagc aaagacaatg ttttgtttga cgattttcaa tgttttcttt gctaaatgga
     2341 ttgcttctgc aatcttcgat ggttgatcat tcatgatgac tacatctgct gcttcaattg
     2401 cagcatcgct tcccaatcca cccattgcga ttcctacatc tgctcttgct agcaccggtg
     2461 catcgttgat tccatctccg acaaatgcgg tctttttatt gtttctttgt aagatttcct
     2521 ctaaccgctg cactttatct tcaggaagca attcgctata tatcttgtcc acgcctactt
     2581 gcttcccgat atgatcagca atttttttcg agtcgcccgt caacatgact gtgttcttca
     2641 caccagcctg ttttaattga accaatgcgt ctacggcatc ttctttcaag gtatctgcaa
     2701 taacaagata accactgtaa ctttgatcga tcgctagata aagcaatgta ccgatttctt
     2761 gacttaaagg aaaagagatt tcaaatcttt ccatcaattt gtgattacct gctaatactt
     2821 gtttgccatc aacttcagct aagatccctt cacctgcaaa ttcctggata ttagttgttg
     2881 gtaaaagcgg acctgcgtag ccttctaaaa cagattgagc aatcggatgt gtagaaaact
     2941 gttctgcact cgcaatatat tgcatgaatt tctttggatc gatttttgta tcgatcgtct
     3001 ggatcgaaaa gtcacctttc gttaatgtgc cggttttatc gaataccact gtctcggttt
     3061 gcgcaagcaa ctccaagtaa tttgaacctt ttactaatac accgatttta cttgcgcctc
     3121 cgataccgcc aaagaaacta agtggcacgg aaatcactaa tgcacatgga catgagatca
     3181 ctaaaaatgt caatgctcga tagatccatt cagaaaacgc cgctccagaa acaacaagtg
     3241 gaggtaaaac agctaataaa acggccaatc ctacaacgac tggtgtgtaa tagcgcgcga
     3301 atttagtaat gaaattttca gctggtgctt ttttactgct ggcattttct actaattcta
     3361 ataatttgct gatagtagaa ttttcataag atttttctac ttgaactaaa aatggtttat
     3421 ttttattgat aaatccgctt aatactgttt caccaacata tacagattta gggactgatt
     3481 ctcctgtaag tgctgacgta tcgactaatg attctccttc gatgatcgtt ccatctaacg
     3541 gtacacgttc accaggcttc acaagtacaa actgaccgat ctgcacgtct tcagggttca
     3601 cggtcatcaa tccttccgtc gtctgcacgt gagctgtttc tggacggatc gccatcaatt
     3661 cgcgaatcga ttttcttgaa tgactgactg ccaatccttg gaaatactcg ccgatttgat
     3721 aaaatagcat cactgctacg gcttctggat attcaccgat caacatagcg ccaatcgtag
     3781 caacagacat aagaaaattc tcatcaaaga tttttccttt gacgatattc atcactgcct
     3841 tcttcactac atcatatcct atcagcagat aaatcaataa ataccctatc aagcgaattg
     3901 gttcattaaa atcaaataat agcaataaag cgatacctgc aagggaaaat aaaatccgga
     3961 acagcgtatt tctctctttt tcatttccat gttcagatac tttttcctta tctatttctg
     4021 ttactttgac atctggttct aattccttca ctactttttt tgtttcttgt tcaatcgtag
     4081 ccaaatgatc ttcctctgcg tcaatcgtta gttttccaga agtgaagttt accgttgctt
     4141 ccttgactcc attgatcttc tgaactcctt tttcgatttt cattgcacag ttcgcacaat
     4201 ctaaaccttc taatctgtaa cttttcattt taatgacctc ctcgcctcaa catatgaaca
     4261 tctcttcata actaattata aatgaatggt tattcatatg tcaaggtatc cgaaagaaaa
     4321 aatgaaaaac atctgcatcg gaaaatttct tccatacaga tgttttggct tattctttct
     4381 ttttctcttc gatcattgcc cctgctctta tccaacccgc acttgccttc ttgatcttga
     4441 caggatagca actaagtttg aagcctgttg ctggcaattt gtctaaattc attaattttt
     4501 cgataggaca atatcttttt tcaatccctg caaaatgtcc ttcccagata ttcgaagctc
     4561 cactacgctt tcaaaaatat agaaagagtt ctttaatgaa aattatttca actttccata
     4621 aacagtaatc ccatataaat aaaagacgta aaagtcacat gggagaactt atacaggaaa
     4681 acacatagag tcaggtgaaa tacatgtatc ccacctgact ctatgcgttt tctaaccttt
     4741 attattctct ttttatacaa tttctgcacc gaatggcatc aacgccaatc gagcaagttt
     4801 gaaagattgc ttggcaaaag gtatccctat gatcgtgata catagaagga tgccgctgac
     4861 gacatgtgcg agagcaattg gtaggcctga aacgatcagc cagatgatat taacgatcaa
     4921 tgacatgcca gactggtgat aaattacttc tttgccaaaa ggcgcaaaag aaagggaggc
     4981 gatcttaaaa cattgcatac cgattgggat acctatgatc gtgatacacc aaagtatccc
     5041 cgctgctaac cagctaagac caccgattag tccgccgaat ataaaccaga tgacatttcc
     5101 taaacaactc attgtatttc tccttctatt actgtttttg attaaaactg ggcaaaaatt
     5161 gattttattc ttcttttttt agcttccagc atcaagtatt ctgcaaattt tttttggatt
     5221 tcttccgtat tttcttttgt tactaatgtg tgttggatta gttttcctga tggtcgctga
     5281 tccacccgtt cttctgactg ttgcacgtcc gcttgcgcaa atccgataat ccgtttttct
     5341 tttgttacag caacgagcaa tagtttattc ttatcattta ggtcagctgc cgtttttgct
     5401 tttacgaatg attctggatg atcagtaatc agctgattga tttgaggtaa atcttctttt
     5461 actgcccacc gtatttccat catttctcac ttttctttcg ctcattttta tctccactaa
     5521 aaaaatcgac tgcggcaatt gcatctatcc agctttgtgc aatgatctca tgtccgccaa
     5581 tcgttgggtg gaccccatct tctcttgtat atttcgaaaa accataagca atccctaaag
     5641 cattgaatat gccatctaaa ggaaccagca atgcgccata ttccttagca agtttacgaa
     5701 caatttggat tttagggtct aagtctttac gccagccatg acggtcgtcg gttataggaa
     5761 gtacaaacgg ctccatcaag atgatgttgc agatttccgc tgtttgaagt tcatttagta
     5821 attttcgata aacggattca aattgctgcg cagatttctc agttccgaat atagcctgat
     5881 cgctagtatt atgccaggta tcattgattc cgatcaaaat cgatacatag tcaggttgta
     5941 aagctaaaca atcttcttgc cagcgtactt gcagatctgc aattttgtct cctcctatcc
     6001 cacggttcat gcattcaaat ttcatcgttg gatattggga gattagtttt ccggcaatca
     6061 aaagtggata acctttacct agatcagttg cttctgctcg gtctcttcct gcgtctgtaa
     6121 tgctgtcacc gataaataat atacgttttt tcatttgtca aaaactcctt tttgaataaa
     6181 acgatgattt tcttccttat attatcccat aagccctatc aagacgaaag agaaaatata
     6241 tgtataaaaa atgacaccag cctagtccct tcaatcaatt gaatgaacgc tcatcaagtg
     6301 tctagttttt tatacttttt ttcttaacgt gccggattcc ccttgattcc ttcgttgttt
     6361 ggtccagaga aatcgatcac acctaagctt ccgtcaatca gaccactgat gacgccatca
     6421 gaacatatat ttataggctc atctaagact tccagtaaat gttcttttac taatatctct
     6481 tctagattgc ttgggataga ttggtcataa ctttatctgg tccgatgatt tcaaggatga
     6541 attaaactta catatggatc attgcatgct gaaaatacgg acctactcca tcttcgaatg
     6601 ttactattag tttgttttca ggtactagat gctgctttat ttcaacagca gaagcatcat
     6661 caaatcagat ttccatttga ataaccttct ttgtatatgt ttgattgatt gcgatttcgt
     6721 tatagaacct tgtgaatcaa atagcaattt cttttgcttt cttctcttgt ctgctggaaa
     6781 cttcctttat cccgtatttt aaaaaaagaa ctgcgagagt tcgcagttct tttttttaaa
     6841 taaacgttgc tctccggcca actcctcggt cacaagtcac aatagtcatc aaacatgaaa
     6901 aactgttttt tgaaattact ccttgtgact cggagctgaa cggcaggcgc acaacctctt
     6961 gatataaacg gtgttcaatc agctgaccct cgatattagc taaaaaaacg gtaaaatatg
     7021 agaagctatt tttccgtttt gtttctctaa tactcaggtc aaggcactga tttcacaacc
     7081 tcttccttaa acggtgttca aaagccagtt tctcggtatt aagccaaatt tatgcaaaaa
     7141 tgtggaaagc catttccaca aaatttttct taatactcga aactaaacag ctttttcaca
     7201 acctctccac taaacggtat tcaaaagctt acatctgcgg taataagtcc cgccaattca
     7261 aaaacatgaa cagctgtttt tgcttggctg ttctaattac ttgatgcaga acagcttttt
     7321 catcacctct tatggataaa ttcggttcaa caaacgtggg aatggaatag cttcacgtac
     7381 atggtcgata ccagcaatcc aagtgactgt tcgttcaagg cctagaccaa aaccagagtg
     7441 cggaacagaa ccgtatttac gtagatcaag ataccatgaa tattcttttt catccaaacc
     7501 gtgattacgg atttgttcta gcaagaaatc atagtctgtt gcccgttcgc ttccgccaat
     7561 aatttcaccg taaccttctg gtgcgatcat atctgcacaa attaccacgt cttctcttgt
     7621 tggatgtggt ttcatgtaga atggcttgat ggcttttgga tagtttagga taaagacagg
     7681 ctgttcgaat gaattcgcaa tgaacgtttc atgaggtgaa ccaaagtctt cgccccattc
     7741 gatgtcatca aatccatttt tcttcagtaa ttcgattgca tcatcgtaag taatacgagg
     7801 gaatggcaat tttgtataag tttttaagac ttctttgtct cgtcctagta catctaatgc
     7861 atattcgcaa tgatctaaaa cattttgtac taagaatgct acatattgtt cctgtacttc
     7921 taaactttct tcttgatgag tgaaagccat ttctggttcg atcatccaga attcgatcaa
     7981 atgacgtcgt gtttttgatt tttcagcacg gaaagtcgga ccgaatgaaa agacttttcc
     8041 gaaagccata gcagcagctt ccatgtataa ttggccactt tgagataaat aagctttttg
     8101 atcaaagtaa tttgtttcga atagatccgt agtgccttct ggtgcagaac cagtcaagat
     8161 cggcggatcg attttgacaa aatgatgttg attaaagaat tcatacgttg cacgaatgat
     8221 ttcatttctg atctgcataa tcgcatgttg tcttgaagaa cgcagccata aatgacgatg
     8281 atccatcaag aaatctgttc cgtgttcttt tggtgtgatc ggataatcgt ggctctcgct
     8341 taccacttcc acatttgtaa ttccgatttc ataaccaaat tttgaacgac tgtcttcacg
     8401 gatttctcca gttactaaca cggatgtttc ttggtgtaga tttttagctg tttggaaaac
     8461 ttcttccgac acttcgcttt ttacaactac accttggaaa aaggctgttc cgtctcttaa
     8521 ttgtaaaaat gcgatttttc cgcttgatcg cttatttgcg acccaagcgc cgattgttac
     8581 tgtttctccc acatggtttt tcgaatcgat gatttgaatt tgttccacgt atgactctcc
     8641 ttttatattc cttgaatttc ttcaggatta attttgactt ttactctcaa taaattgctt
     8701 gattctgcgt accgcttctt ctaacgtagc gcgatcagtg gcataactca tgcggacatt
     8761 ttctggtgcc ccaaagcctt cgccagtcac aagcgctacc cctgtttctt ctaaaagatc
     8821 ttctacccat tgtgtgacat tttcatactt acacatgcgt agcgtttctt ttacattagg
     8881 aaaaagatag aaagctcctt gcggcttttc aagagaaaca cccggcagtt ctgccacaag
     8941 cggatataac gtattcaggc gttcttcaaa ggcgttccgc atttcttcta ctgtatcttg
     9001 ctcacctttc aatgcttcaa cagctgcata ttgactgact gctgtcggat tgctagttga
     9061 ttgggaagca acagcgatca ttccattgat gatcacagga tttcccaccg cataaccaat
     9121 gcgccagcct gtcatcgcat atgttttaga cacgccgttg atgatgatgg tctgattttt
     9181 gattgcttct gaaatcgttg caattggagt aaactcattg ccattataaa ctaaacggcc
     9241 ataaatatca tcagcaacta tcaaaatatc attttttact gcccattcac cgattgcctg
     9301 cagttcattc ttgctataaa tcattccagt cggattcgat ggagaattga tgattacggc
     9361 ttttgttttt tctgaacgtg cttgttctag ctgttcaaca gtaactttcc agctattgga
     9421 ttcttcccct ttcacaaaga caggaagtcc ttctgccagt tttacttgct caccgtaact
     9481 gacccagtaa ggcacaggaa tgatgacttc atcttgcggg tcaaggatcg tttggaaaag
     9541 ggtatacaaa gcaaatttcg ctccgtctgt tacgactgtt tgtgaaggtt catagacaag
     9601 tccatagttt ttcttcagat aatcaacgat tgcctgtcga agctctggga ttcctgctgt
     9661 tggtgtataa tagctagctt tcccattgcg gattgcttcg attgctgctt cttggatgtt
     9721 ttctggtgtc gcaaaatccg gttctcccac agtcaaactc agcacatctc tgccttttgc
     9781 ttttaatgcc ttggcctttg ccgcagctgc caaagtgaca gacggttcta atcgttttgt
     9841 tctttttgat aactccatcc cattcattcc tttacctttt aaattccctt gattgtcttg
     9901 acttcatctc cagattcaaa gccaatcagg taataattca gtttcccatt tgtttctttt
     9961 cctactactt cccacacagg ctgatcatca tacatcccta aagcagcttt ttcgatttgg
    10021 atttcaggat gggccgcagc aattgtctgt tttgcttcgt tttcagtcag tccctttgtt
    10081 tgatccaata cttttacttt ttcaccagat ttaggaatga taacggcgat ttcttttcct
    10141 ttatcatttg tacctgtcag tgaaaagtat gtcttctttc gagtaaacca ataaaaatga
    10201 tcggtttcct caagatttgc atatttcttt gcgatttcta ctgcttcttt cttcgcctgc
    10261 accgccggac gactggaacg caagtaaaaa atcgagctga tcacgatgac cgctaataaa
    10321 aatacgatca agccaagtaa cacgcgatta atcgtttttt cctttgtctg ttttttcttc
    10381 aagggtcgtc gctcctttat cttcattcct tttcattata gcagatttta attatgaaaa
    10441 aagacagctc ctctaacttc cttcttcatt tttctttaag aattcatgga tatcctgata
    10501 gatttcctcc atagctagct ctttgatcgg tacttttttc ggtaatgcat ggatgatccg
    10561 tgcgccatat tttgcagtga ctagtcttcg atccaaaata agcaatacgc cacgatctgt
    10621 ctccgtcctt atcaagcgac ctaatgcttg gcgtaacttc aaagctgctt taggtacgga
    10681 ttcctggtaa aaaggattga tcccctctga ttctaaataa gcgttcctag ctttgaccat
    10741 cgggcgaagc ggattatcga agggtaaacg tgtgactaca acgatctgca aagcatctcc
    10801 aggcaaatct acaccttccc aaaagctgtc agcgccaaac aatacgcttt tttctgacaa
    10861 aatgaagcgt ttcaaaagct tctcccggct tccaccaaac ccttgagcta gtatttctcg
    10921 tcctttttct agcatagaca gatgcatttt ctgatagacc ttctgcaaaa catcatgaga
    10981 agtgaataac acaagtattg gccgatcttc ttgttcgatc agacctgtaa gtgctgtctc
    11041 taaataatcg atatatgctt gattgctgac ttgatggacg gcaggtgcct cttttggcac
    11101 atagatcctt gcctgtttct cataatcata aggagaggca atcactttaa gaggtgctgc
    11161 ttcaatgcca agcctcttag agagatagtg tcgattaggg ccgatcttca gcgttcctcc
    11221 aatataaaga atacgatcat atcgaggata ccaaacagtc gacggcaaca tagccgcttg
    11281 aaaatcatgg agatgaaaaa tcatctgctg cgctgtgttc ccaggaacga accaatggat
    11341 caaatgatct cgccagtctt ccagccattg atccatcagc aagtattgct tgtctaattg
    11401 atcaaatagg ctatataaac ttgctaaatc gatccgcatc tggtttgtcc agctttcttg
    11461 gataatctca aaagtcagac gcatttgtga ctgtagctgc tggatctcct gataaaaaag
    11521 ctgcaggtga tcaatggctg tcccagattc cagtggcagc tgatccaaca tctcttttgt
    11581 catcatgact tcttctggat actgtccgtt aggttgcttg ccgctcacta aactcattaa
    11641 tccttctgcc atacaaatct gtgcttcgca tagcgcagaa agttcttctc gataaatcga
    11701 taaccagcgt aaggcttcat gttctttcgg taaatagctt tgtattcggt caaacagctg
    11761 atttggttct tctaattgct ggatttgttt atggaaatag ttaatactta atcgtttgtc
    11821 atttactttt tcagcgattt ccggcaaatg atgtacttca tcgatcaaca aaaatggact
    11881 agctggaagc aatggttctt ttcgctgtgt ttcttgtact aaaaacgcat gattgacaat
    11941 caaaaaatta ctttgcctga ttttcttttg caagaaacga acaaagtctt gttcgtaaaa
    12001 tgactgattt cttgctaaaa atccaatacc tctgtgcgcg atatctgcaa agaatgaatg
    12061 gttcaaattt gttaaatgta attcatccaa atcaccagtc ttcgtttgcg tcagccaaac
    12121 taagaccgcc atttgataca aagcatattg tttttgttct ggcggttcca caagtgtgcc
    12181 tttaaaacgc tgcaaatcaa tatagtggcg atagcttttg ataattacag gttgtatggg
    12241 ctgatctagc aattgattca gcaatggaat gtctttttct atgatctgct gctgcaaaac
    12301 tagcgaaacg gtactgatga cagcgggttt ttcaggtgta gccaaataac tcaatggcag
    12361 cagataaccg attgttttac ccattcctgt agctgcttcg atcatcaaat cttttgattc
    12421 atcttttgtg aaatggtcgt agaccgcatt catcagtctg ttctgttctt ttcgatacat
    12481 cagtgtttta ccaaacattt tttcttttgc ttgttttttt cttggatatg tccgctcgcc
    12541 ataatggacg gatgtgaata gttccacttc ttttttctgc aaagctagcc catcgacgat
    12601 ttctaatgag ggatcaagtg gctctggttt ttctttcatt tcttcaatca catgataaat
    12661 gaaacgactc gtatccatac ctgtgtgtct acttaatcgc gcaatctgct ctaacgtgat
    12721 gattggcaat tttctcatcc gttcttcgat cagcaaaaga agttgacctg tcacttcggc
    12781 atcactatct gcctgatgag gattctcatg aataaatcca aggctttctg acaaatcagc
    12841 taagcgaaag cttggttccg tcggcaagaa aatttgtgca agttctactg tatcgatgcc
    12901 tggtatcttc aaactaggaa gtccgcatcg catgagttca tggttcaaaa aattataatc
    12961 aaaataaata ttatgcgcga caaatatggt gtctgccaaa agattgtaaa tcgtttgggc
    13021 gacatcttcg aaataaggcg ctttttggac gcgttgattc gtgatccctg ttaaatgctg
    13081 gatttgtttt gaaatcttcc gccctggatg aatatcgatc gaaaaacgtg aagtgatccg
    13141 acctgattca atcatgacgc agccaaattg gatgatccga tcttcttttg gattcgtccc
    13201 agtcgtttcg atatcaacga ctgcataagt tcttggtttc aaaatatctt cctcttctcc
    13261 tgcctctaat gttcttttga aattatacta caaagtgcag aaaaatactc tcatcgcttt
    13321 ttaaagaaaa tagacaaaaa cgcccagaca cgcaaatgtc tgggcgttta ttttttagta
    13381 taggttaatt aagctttagt aacgtttgtt gcttgaggtc cgcgttggcc ttcttcaaca
    13441 tcgaaagtta ctgcttggcc ttcttctaaa gttttgaatc cgtcgccttg gatagctgag
    13501 aaatgaacga atacatcgtt tccgttttct gcagtgatga atccaaatcc tttttctgag
    13561 ttaaaccatt ttactgtacc tgtttccata ataaaaatcc tccttgtgta tcaacacata
    13621 ttttgcaatt acttgaatgg tgtatatctg gaagatgttt atttgaaaca agctaccaca
    13681 gattaccgaa caaaaactac tcctatagta tatcataccg tttacaaaaa agctagagtt
    13741 tttcgacttt ttttattaaa aaaagttttc tcagcgatta cataaagtga aaaaccgaac
    13801 ttttttttaa aataaacgac atattgttca gttggtgttt ttttgctctg atgttctttt
    13861 ttaaactaaa aaaattattc tttctgacta cttatcggtt ctgtttcaac ggtcgaggct
    13921 ggggaagatt ctttagtagg tctgatgttc tcatggtatt tctgatagcc tatgacagtt
    13981 accagaagaa caaggcaaac caatacgacc aacgagatta gtttttcttt tttgctcata
    14041 tctatacctc ataaataaca ggatgatgtc catcatattt ctgagtatga gtaaaagcaa
    14101 aagctgcagc tgtagaatgt aagaaatgcc agcaactttc ataatcacag gtcggacagt
    14161 accaaaagta accaaatctt ggctgcaaag accgttcttc tgtttcagga atcgcagaat
    14221 caagatctgg tgtctgtaca taaacatttt tgtacagacg tgtgcctgta ataggaaacc
    14281 gctgtgtttc ttcagcaaaa actggctgac ttgttaaact tagggataga gacagcaaac
    14341 accataacag tctttttttc ataaagacct ccttatcgat aagtttttcc caattaaaat
    14401 catatctcaa gaacgcccgt tattcacatt ttgttcataa atgatgtttt ttgtatcata
    14461 atcgtcaaaa agaggtcgtg accacgtcac aacctctttt ttaaacggtg ttccagaagt
    14521 agcttcttcg gaaataagcc gaaatttcac aaaaatttga gaaataattt ttgtcaatct
    14581 cttcttattt cttgaagctg accacttctg tcacaacctc ttccttaaac ggtgttcaaa
    14641 agcttgcatc tgcggtaata agcccaccaa acaaaaaata tgaagagcta tttttgcttg
    14701 ctgttcttat tacttgatgc agaacagctt tttcacaacc tctcatacac ggtgtttaat
    14761 cagctgacct tcggtattag ctcaaaaaac ggcaaaatat gtgaaactat ttttccgttt
    14821 gtttctctaa tactcaggtc aaaacactga tttcacaacc tcttttaata acgaagaatc
    14881 gctgtcagac tcttttcatc tggcgcatct ttttgatcca aaataaacac ttttccgcca
    14941 ttaatgatca catcatctgc taatgcattc aacacttgac gccgatcata ttctgtttca
    15001 ggatcttcac cgaaaccatc agctaagttt gacgtagcga taaataaatg tgacactttt
    15061 ccttctttcg cagctggaac gatatcaact aactgatcga tgaatttctt atctaagagt
    15121 ttattgtatt cttttgattc ttgagctgcg agttcacttg acagcttctt cgccccttct
    15181 tcgatatctc taaaggatag ctgcgcagga gaagcagaaa tcgcaacgtc tgcacaataa
    15241 tagggatttt tagcaatttt tttgaacatc gtctgatttt ctggtagagc aaataaataa
    15301 atcggccatt gttctggatt ttcgaaagaa tccttcaagt acgtatcaac tgcttggtaa
    15361 tagttgaccc aatcgatctc tacttcttca tcttttggat ttacgccatg gaaagttact
    15421 ccatctcggg ctccgcctcc tccattagaa gagaagttca aaccgccacc tgtcagttca
    15481 gatcccaatg cagtaacgac atcaaccggt gccccttctg gtagagatac ttcttttact
    15541 tgtttgttgc tgacttcata caatttcatg gagtcgcggt tcaatcccaa taaataataa
    15601 gaatagttga actgcccatt tttgataata gccagtaaat aaggaagatc acttacatag
    15661 tattgatcgt ctaccgggat actcaaacga tggatatagg tttggtcagc agttataatg
    15721 accgctacac tcgtagttgc actacgccaa aacgaaggat ctcctaacaa attttcaatt
    15781 ttttcttgga acggggacca gtcatgttcg gaatattttt tctcaaaacg tttctttgct
    15841 tctttcgcaa aatttttgaa tttgatctga tctttttcca catcttgatg ggcgacatgc
    15901 gtattcagca tgatcgtgac gaatggtcct ttagcgcctt ctgaagtcaa ttgtgacaat
    15961 aattctttat ccttttttgc cataaacgta cccctcctaa aaaaatcatt cctttgtttc
    16021 tatctaaagt ctaccacaac actatttttc catacaataa aacgtatcta aaaaaataaa
    16081 acggtttcta cggttttaaa tttagctatt tttttaagtt atcttcataa tttcctcaat
    16141 tatttagccc cagtcttcaa ctattcttca tgaaatgctg ataaactaag aaaaagaata
    16201 aaagaggtgg atcttatgca tttgattatg attttcagtt tattaagtat tatcagttta
    16261 tttgctttca gcgcttcccg cttattagat gcggaaacac agcctattcc tgtaaaagta
    16321 cgtaaaaacg accgctaacc ttccataacg tgcgttctta tcctaaagtt ttttcagaaa
    16381 cattgaaact ctctcccctc tctgataaaa ttttaatttg tagcgaaaca aattaattac
    16441 aaggagatcg gatatgtcca taaaaaaaac acgtctagtc ctattattgg ctagtctcat
    16501 tctttgcctt gcttcttttc taccagctgt tgctgtgcaa gctgaagata ctttcaaagt
    16561 aaatgcaaaa gcagcctttg ctgtagatgc gcaaagcggt aagattcttt atgatcaaga
    16621 tggagaaaaa accatgggga tcgcttcaat cacaaaaatc atcggtcttt acatcgtcct
    16681 tgatcaagta aaagaaggga aactatcatg ggatgataaa gtttcaattt cagattatgc
    16741 agaaaatttg agtgtcaccc cagatttatc aaatgttcct ttgcataaag aaaacaccta
    16801 caccgttaaa gaattattcg actctgcaat catccagtca gccaacgctt caatggttgc
    16861 cttggcagaa aaaatctctg gcagcgaagc aaaattcact gaacgaatga aagaacaatt
    16921 gaaagattgg ggtatcaaag atgcaacgat cgttaatgca tcaggactga ataactctta
    16981 tcttggcgaa aaccgaccag aaggtactgg agaaaacgac gaaaatcaaa tgtctgctca
    17041 agatgtggct atcgttgccc gtcatttgat cttggatttt ccagaaatac tggatgtatc
    17101 tagcactacg acacaaatgt ttggcgaaaa cacgcaatca ccagtagaaa tggtcaactg
    17161 gaactggatg ctcccaggat tcgtgaatta taaagaaggc gtggacggat taaaaactgg
    17221 tacgactgaa cttgcaggag cctgtttcgt cggtacgatc actaaaaacg atcaacgaat
    17281 catcactgtc gtattgaatg cagacggcca tgcggaaaac ccaagtgccc gtttcaatga
    17341 aacagctcgc ttaatggatt attgctacga caattggtca gaaaaagagc ttggaaaagc
    17401 caatgcaagt atccctagtc taaaaaccat tgatgtaaaa gacggaaaag aatcaacagt
    17461 gcccgttgtg cttaaaagtc ctgtaaaagt atgggtacgg aacgatatgg atactggaaa
    17521 attaacaatc acaccaactc ttgacaaaaa acaagtcact gacaatgaga tccaagcacc
    17581 tatggataaa ggaacaaaaa tcggtaccgc aacgatcacc ttggcagaag ataaattagg
    17641 ttatcttgaa gacaacaacg cgccatccac agaaatcatc acggataaaa ccgtagaaaa
    17701 agcaaatatt ttcgttattg gctggcgacg cgtcgcagaa tttttcggta acttgtttta
    17761 attgaacaaa aagaaaaaag catctttcca tgtggaagat gtttttttgc tttttctagt
    17821 ttaaataaca gcttttttca tctattttcg ttatactgta taagaaaaag gagttgaatt
    17881 tatgaatcta accagagatc tgattttttt ggttctctat cttattgggg tattctccat
    17941 cgtttattgg cgaaaacaga aaaaggatcc ttccttgttc ttttacagca gtacatggac
    18001 gtttgcggta atcttgactt attttgtcgt gttggaaatt ttttattcga ccttttattt
    18061 tttgattccc ttagtgtttt tcagtatctt tgccttttcc tatttttcag aaaagcgaag
    18121 gctgttgaat ggtcttttat tcaatatttt cctcattagt tttggtatct acttgtttgt
    18181 cttgctatac gaaacacaaa atatttttct tggcggactg attgccttga tcacgatccc
    18241 gttactgctt gtctttctat tcggcattta tggattgatc gtttttcttt tttggaacgg
    18301 tgtcacagtt ttacgtagag agtcgcattc attagctaat cttttaacgt tgatactagc
    18361 catttttctt acattgtttc ttgtttttga ctttttcttg ttaaaatatt taccacaatg
    18421 gataaatgct ttgtttttct gcatcccatt gatcttgatc tatctattta tcgtattcta
    18481 caactttttg actgtctcat tcttgtatca gttcaaccgc cctcgataca accaagactt
    18541 catcgttgtg ttaggcgccg ggttgatcaa tggagaaaca gtttctcctc ttcttgccaa
    18601 gcgaatcaat aaggcgattg ctttttattg ggcacaaagc cgtgcgacat taaatccgcc
    18661 tatcctatta atgtcgggtg gacagggagc agacgaaaaa gtaccagaag caatggcgat
    18721 gaaacaatat gccatggaac aaggaattcc tgaaagagat attcttgtcg aaaccaattc
    18781 gacaaccact ttggagaata tgcgctattc aaaggaaatc atggatcagc aaatgaaagg
    18841 tccctatcgc gcgatcttca gttccaacaa ttaccacatt ttcagagctg gtctctatgc
    18901 acgacaagcg aaactgaagg caaatggcat tggggcaaaa acagctttct attacttgcc
    18961 taacgcgttt ttaagagaat acatcgccat cttgatgatg aacaaaaaaa gacatatgat
    19021 catttgcgga ttgcttttcg caggttccgc attcttatca ctgatcactt tacttttcta
    19081 aaaaaacaag gtgtgacaaa acatatgtca caccttgttt ttttctttca ttctcttaac
    19141 tattggcaaa aagagtatcc cttttctgac cgctacttgc tgagcagaat aaataccgct
    19201 gttgcctgaa cacataaagc tgatcaagca gatcataaag aagtatactg ccgcttgtga
    19261 accgaacaat tcgatcccca tcacaaagca ggcaatcggt gtatttgtcg caccagaaaa
    19321 tactccgata aagcccaatc ctgcaagaaa aggaacagaa acatggagca aaggcgctag
    19381 tgctgcacca agcgttgcac caatttcaaa caatggtgtc acttctcccc cttgatatcc
    19441 cgcgcctaaa gacaaaactg tgaagaataa cttcccaata aaatcataga catgtgcctg
    19501 tccattaaat gattcctgca gtaatggaag actcaatccg agataacgtt gtgtttgcaa
    19561 aatcaatgct gcggctacaa ctacagcccc acctatcgta tttcgccaaa caggatgagg
    19621 aatccattgt gcatatcgcg cttttaaaaa gacgatcgaa cggctgaata cccaaccaat
    19681 caaaccaaaa gcaatcccag caacaaaaac tttgaagaac agcaacatac tccattcagg
    19741 aatcacaccc atttggtaat gtagatgaga aacaccatag ctttctgtca taaaatttgc
    19801 aaacagtgca gcaaagaagc tagggaagat cgcttctgtt cggactttcc cgattgccaa
    19861 cacttctaat ccaaataatg ttccagctaa aggtgtgcca aatacagaac taaaacccgc
    19921 actgattcca ctgataatca agatttcccg ttctgattta tccaatcgga acaaacgtgc
    19981 tgtattatct gctaacgctc cccccatttg gactgctgtt ccttcacggc caacagatcc
    20041 tccaaataaa tgggtagtta tggttccaaa cagtgtaagt ggaataagtc gcaacgggat
    20101 tttttcttct ccaccatttc cttgatcgat cactaagttg tttccacgac tagaaagacc
    20161 gccgtgatac gcatagagat aagcaaaaag cgcaccacta actggtagta gataaaggag
    20221 ccaaggatgt gatagtcgga tatctgtcac aactgtcagg ctatttaaga aaaaagcaga
    20281 taagctcccc atgaatatac cgagaatcgc tgtgatcacc agccacttca gcatgtacac
    20341 taaaatgcgt actggactcg gtaattgttt ttccataaaa aattcctcct caataaaaa
//
LOCUS       DAZUJR010000053        20181 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.053, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000053 DAZUJR010000000
VERSION     DAZUJR010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20181
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.053"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            208..1014
                     /gene="proB"
                     /locus_tag="ACG804_001837"
     CDS             208..1014
                     /gene="proB"
                     /locus_tag="ACG804_001837"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HFS4832766.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            1011..2258
                     /locus_tag="ACG804_001838"
     CDS             1011..2258
                     /locus_tag="ACG804_001838"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HFS4832767.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            2334..2678
                     /locus_tag="ACG804_001839"
     CDS             2334..2678
                     /locus_tag="ACG804_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832768.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(2795..3121)
                     /locus_tag="ACG804_001840"
     CDS             complement(2795..3121)
                     /locus_tag="ACG804_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832769.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(3494..4696)
                     /locus_tag="ACG804_001841"
     CDS             complement(3494..4696)
                     /locus_tag="ACG804_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4832770.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            4813..5328
                     /locus_tag="ACG804_001842"
     CDS             4813..5328
                     /locus_tag="ACG804_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFS4832771.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(5527..5973)
                     /locus_tag="ACG804_001843"
     CDS             complement(5527..5973)
                     /locus_tag="ACG804_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HFS4832772.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(6020..7498)
                     /gene="msr(C)"
                     /locus_tag="ACG804_001844"
     CDS             complement(6020..7498)
                     /gene="msr(C)"
                     /locus_tag="ACG804_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HFS4832773.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(7852..8481)
                     /locus_tag="ACG804_001845"
     CDS             complement(7852..8481)
                     /locus_tag="ACG804_001845"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFS4832774.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGVEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(8465..8929)
                     /locus_tag="ACG804_001846"
     CDS             complement(8465..8929)
                     /locus_tag="ACG804_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFS4832775.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(9416..10684)
                     /locus_tag="ACG804_001847"
     CDS             complement(9416..10684)
                     /locus_tag="ACG804_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFS4832776.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(10915..11652)
                     /locus_tag="ACG804_001848"
     CDS             complement(10915..11652)
                     /locus_tag="ACG804_001848"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFS4832777.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(11719..12288)
                     /locus_tag="ACG804_001849"
     CDS             complement(11719..12288)
                     /locus_tag="ACG804_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DapH/DapD/GlmU-related protein"
                     /protein_id="HFS4832778.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLLVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12416..13288
                     /locus_tag="ACG804_001850"
     CDS             12416..13288
                     /locus_tag="ACG804_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFS4832779.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            13630..14502
                     /locus_tag="ACG804_001851"
     CDS             13630..14502
                     /locus_tag="ACG804_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFS4832780.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            14499..16457
                     /gene="nagE"
                     /locus_tag="ACG804_001852"
     CDS             14499..16457
                     /gene="nagE"
                     /locus_tag="ACG804_001852"
                     /EC_number="2.7.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015572 - N-acetylglucosamine
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-specific PTS transporter
                     subunit IIBC"
                     /protein_id="HFS4832781.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(16708..17559)
                     /locus_tag="ACG804_001853"
     CDS             complement(16708..17559)
                     /locus_tag="ACG804_001853"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFS4832782.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            17682..18149
                     /locus_tag="ACG804_001854"
     CDS             17682..18149
                     /locus_tag="ACG804_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HFS4832783.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(18412..18894)
                     /locus_tag="ACG804_001855"
     CDS             complement(18412..18894)
                     /locus_tag="ACG804_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFS4832784.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(18994..19857)
                     /locus_tag="ACG804_001856"
     CDS             complement(18994..19857)
                     /locus_tag="ACG804_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFS4832785.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
BASE COUNT         6067 a         4156 c         3662 g         6296 t
ORIGIN      
        1 tactcctatt ctaacatatc cgaggctgta aaagactttc tttacaaatt cttcaagaaa
       61 ttctgctatc ttaaagtaaa ccattaattc gttctttttc caaacgacta caagttgtac
      121 aaaaaaacta ttttttacat gactttactc gtcaaaacaa gtagaataga acgaaattaa
      181 tgagtggata tttgattgag gtgtcacatg cgtaaagaaa ttaaaaatgc aaaacgaatt
      241 attgtcaaag taggaacaag tacattgatt tatcccaatg gaaatatcaa tcttgcggca
      301 atcgatcagt tagcttttgt cctttctgat cttagaaatc ggggaaagga agtgatctta
      361 gtctcatcag gagctgtagg cgttggtatg cataaattac atttgtcaga acgtccgact
      421 ttgattcctg aacagcaagc tgcggcggct gttggtcaag ccgaactgat gaatatctat
      481 aatcaaagat tcagtgtata taatcaacag acggcacaga tcctcgtgac aagagacgtg
      541 gtagattatc ctgaaagtcg taaaaatgtg aggaatacat tggaacagct tttgattatg
      601 gacacgatcc ctatcgtgaa cgaaaacgat actgtagcag tggatgaatt agatcatctg
      661 acaaaatttg gcgataatga tcagctgtca gccatcatgg caaaacttgt cgcggcagac
      721 cttttgatcg tcctttctga tatcgacggg ttttattcag ataatccgac tacaaatccc
      781 gaggctcaga tgtatcgcta tatcgataaa atcgatgaaa agattctggc acaagcaggt
      841 ggtgctggta gcacatttgg aacaggcggt atgcagagta aattaaaagc cgcttctagg
      901 atatttgaag caaacagcgc aatgatttta gcaaatggaa aaaatccggc aattattttt
      961 gatattcttg caggaaaaga agtaggtact ttatttaagg aggacttgaa atgactgact
     1021 tgatgcaatt aggacaacag gcaaaagata gcgcgcaaca actagcactt atgcctacaa
     1081 accgcaaaaa tgagctactt gttcaaatgg cacaaaccat caaaaagaat caacaagcga
     1141 tcattgaagc aaatcataaa gacttagaaa aagcagtcga aaacaatatc agtgaaacga
     1201 tgcaagaccg cttgcagctg acacctgagc gaatcaatgc catggctaca gagatcgaaa
     1261 aaattgcttc gttagacgat cctattggaa aagtagatga gatgtggacg aacaccgacg
     1321 gattgagaat cggcaaaaag cgcgtgccac taggcgtgac cggcatcatt tacgaatctc
     1381 gtccaaatgt cacgacagat gcagctagtc tagcattcaa atcagggaat gccgttatcc
     1441 ttcgcggtgg caaagaagca ttcttctcga atcaattatt agtccaatta ttgcagcaag
     1501 tactggtcag tgctggcgaa tctccttatg ccatccagtt tgtcgatgat acttctcatg
     1561 aaactgcagg acagttgatg cgattgacag aatacttaga tgtgctgatt cctcgaggcg
     1621 gagcaaaatt aatccaacga gtcaaagaac aggcaacggt acctatcatt gaaacaggta
     1681 caggaaataa tcacgtatat atcgataaag aagcacagtt atctatggca gtgaacatca
     1741 tcgtcaatgc aaaagcttcc cgtccatctg tctgtaacgc ggcagaaaca ttgctgatcc
     1801 attctgagat cgcacctttt ttcttgccag ctattgaaaa agaactggta gaacacgggg
     1861 tctctttacg tgcggatgct cgtgcgttag aatatctaga gacggctgct ttagcagaag
     1921 acacagattg ggatactgaa tatctagatt atatccttgc tgtcaaagtg gtcgattctt
     1981 tggatgaagc aattgcacat atcaatcggc ataatactaa acattcagaa acgatcgtga
     2041 cagatagtta tgcggctagt caacgtttct taaatgaagt ggacgcggcg gctgtctatg
     2101 tcaatgcctc cactcgtttt acagacggat cggtatttgg ttttggtgca gagattggta
     2161 tctctactca aaagttgcat gcccgtggtc caatggggtt aaatgaatta acttccacaa
     2221 aatatatcat ttatggcgat ggacaaatcc gcgaataatg tttcgtgtga aacattattc
     2281 ccgccttttg ccttttttct gtaaaggttc tatccaacta gaaaggtgtc aatatgtttg
     2341 aaattttaat gatttttttt atttacctta tttctctgaa tatcgctgct tttctgggag
     2401 tcggtatttt atcccttttc tttcaattca aaaaacgaag catagggagt caacgggaaa
     2461 aatggtcgca gtattttgac aaaatcgggc aaaaagggct ggttacacgc ttgcacatta
     2521 gttacatggt tgcattatgc ttattagcga caatcaatta ctattctttt ttcgatcatt
     2581 caatcgctta tacgattacg ctactgattg ctgggatttt tcacttatct tataaatatc
     2641 agctgaataa aaaccacttg aatcggactt tccgctaaaa aatatccgta cgataagtag
     2701 agtgccttga agatcggcaa aaaactgccg gactttttag aggctgtgac aaagattttg
     2761 tcacagcctc tttttccata taaacggcgt tcgcctacca gctgcctggt aaatctgttt
     2821 cctcttcgtt aagaagcgaa aatccgtcaa atgtttcgcc atcataataa cgaagcagct
     2881 catccatgga caagttcatc gttttttctt tttcttcttc cgctgattca gccagtagct
     2941 gttcccgata cacctgatac ataccagcta ttttttgctg catcgctttt ctagtttcac
     3001 cttccgcatt gattattggc aattctttga tatagccacg ataaatcaac cgatcatctg
     3061 aaaattcaat gggtaattca acgagtgtca acccgacttc ctgaaaatat tcttccagca
     3121 tctattatcc ccccattctt tttcttaaat gaattttagc ttacctactg aaaattttcc
     3181 agtttcatta ttttgagaaa aaaagggaat gtgacaaaaa tcgtgtcaca tccccttttt
     3241 ccgaataaat ggtgttcttc tgccaactcc tcaatcataa gtcacaatat tcaacaaaca
     3301 tgagaaactg ttttttgaaa ttgttccttg tgattcagag ttaaacgaca gtctcacaac
     3361 ctcttggtaa acggcgttca aaagcttgca tctgcggtaa taagcccaac caaacgaaaa
     3421 atatgagaag ctatttttgt ttggctgttc ttatgacttg atgcaggaca gctttttcac
     3481 aacctctgat ttcttattct tcttcatttg tagcaaaata attacggtga taaatgatac
     3541 aacatacact gataagaaca atggcacctg caaaataaaa cgcatagctt tcaccaatat
     3601 gttcaccaat cacacctgca ataaatggtg ctaaagctcc accgaaaaag cggacaaaac
     3661 tatagctgga cgaagcaacg tttcgttgca gacctggtat ttccatagca atcgtcgtca
     3721 acagtgtatt gataattcct tggaaaaatc ctgctaacac aatgctgatc ggtacaagga
     3781 ctggcataga agttccagct cctaataaca gcaaacaaat aatgaataag acaaatgctg
     3841 ctaaaattgt ccgataagtc gtaaacttcc gctcaagagc cggtgcaacg aaaatcgaag
     3901 caatagccag aagcacaccc cagccaaaaa atacaaaacc gacttctaat tcagaatagc
     3961 caatcaataa aaatggcgca tacgcaagta aagtaaagaa tccgaaatta tataacaatg
     4021 cgattagtcc aactgaacga agtttatgat tgcttaacgc tttgacacct tcccaaaggc
     4081 ctacttttct ctttggtttc tcagtttcag gtaaaagtac cgctagggct ataaaaccgc
     4141 aaaacatcaa aaatgctacc ccaaaaaatg gataacgcca tgaaccactg cccaagaccc
     4201 caccgactag agggccaaca gccattccgc agccaagtgc tgcttcatac atcatgattg
     4261 ctttttctgt gttaccaact aaaatactga cgatcgttgc taaagcagta gagacaaata
     4321 aagcattccc gacaccccag ccggcacgta acccaatcag cattccgata ttcccagata
     4381 atccgccaag accagcgaat acaacgatga taaacaatcc tgtcatcaat gtttttttca
     4441 aaccgatccg actagataag aaacctgtaa atagcatcac cacaccagtg actaacatgt
     4501 aactagtaaa taacagggtc gtttcagctg gcgtagcgtt taactgtgca gcaatcgttt
     4561 ttaagattgg gtctactaga cccactccca taaaagcgat catacaggta gctgctacaa
     4621 ctagcgctga acttttcccc tttgtttctt catttgtttg ttcttgtata tctatttgat
     4681 tctccaatat ttccatccct ttctctctat tagcatcata catgatttat tttacatgta
     4741 aatatgcaca tgtaaaacgt ggaaacttta ctgtgatata ataaagaaaa taagacgaga
     4801 ggtaggattt ttatgaatac tttagcctat atattattat gcgtgctttt atccaaacca
     4861 cgttctgggt atgaattgaa gcagctgatc acaatttttt gggaagccca tcacagtcag
     4921 atctatacaa cgcttgccaa gttagaccag cagggttatg tgaccgtttt ggacaaagac
     4981 gagcactctc aaaaaaagat ctaccacttg actgatgaag gacgtgctct tgtagaggaa
     5041 tggatcaaag aggaaactcc cgctcctacg caaaaagatg aatttctagc aaaaatctat
     5101 gctttttcga cgctcgataa aacaacagct actggactgc tattcactag agaacaacag
     5161 ctgaacaaaa tcatgcaaaa aaatcaaaaa aaattgaatg acctctcgct agacaagaaa
     5221 caagaatttg gacgttatgt tgtgatccag cgcagaatta tgctttgtca gcaggaactc
     5281 caatggtgtc agcaagtaag agaacaaatg cagcagtttt ttgagtaagg gataaacaga
     5341 acctttctag aaatatctat tgaagagcaa attatcttca ataaaagagc aatacagttg
     5401 gaaaagaaaa agcgatccga acgacaggcc aaaacctatc gttcggatca ctatttttct
     5461 agaactgcat tcaagagact atgacaaaaa gcatgccaag gccttttttc aaataacagt
     5521 gttccatcat tcattacttt gaattgcttt tagcacactt cttgaaagcg ggccaacgat
     5581 gatcaactgc aacggtaaag cggcaatcac attcattttc caagcattca tataagcaga
     5641 gaataattga tcaggtattc cttgttccat gatcacaccg aataaagaca tacatgtcac
     5701 cattcctaaa accatcaagc atgaaatagt taagatcatt tggaccttgc tttctggatt
     5761 tactggtagt ttaaaggcaa tttttttcgc cagcacaccg atgatgaaga catccaaaat
     5821 gaaagccacc acgaatccag gcactagacc aatcaacaaa cttgataaat gaagatcttg
     5881 atgcagccat aaattatacg cgctcatccc caagaccatc aaaaaacaca tcattgttgt
     5941 aaaaattatt ccttcttttt tatttgtagg caatctgtac cactccttta aatttgtcac
     6001 gaaaatcatc gtagcacatt taaaaatttc tcgtaagtac tttttttatt ttctgccctt
     6061 ttatttcata aacttcatca gccgtacgct cgacaaagta agaatcatga gaagtaaaca
     6121 aaatcgttcc cggatatatt tgcattagct tctctaaagc ttcgatcgtt gccatatcaa
     6181 taaaattagt cggttcatct aacagcaaca cattacttgg cttagtaaaa agcaaagcaa
     6241 tcgtcagacg ggtcgcttct cccccactta atgtacataa cggtttcgtc aaagtttcct
     6301 gagcaaaccc taagtgattc agcaaactac ggacaagcga ttctgaaaac tctgtttgtc
     6361 tcatgacaaa acgaatgatg gattcttcag atgtcatttg ataacccttt tgctgatata
     6421 cttgaaagct tactttcgga gagagaagga ttccttctcc ttgtttgcgg atatgttcta
     6481 ataaggttgt cttacctgaa ccattttcac cgacaatcgc gattttttta cctaaagaaa
     6541 actgaaaatc accatttacc agtaatgttc tcccacttct ttccaattgg acattttgtc
     6601 ccatgatggg atagcggctg tggagttcaa gagattttgg tactggaaaa cggatttgtt
     6661 tcatctgctg cggcttggtt gtttctccta ttttttggag tcttctctct aatgttttcg
     6721 cattcttttg gatggctttt tgtacactgt ctttttgttt agaggaagac aaccgatccg
     6781 gtctgatttg ttgctttttc tttttactgg acactttttc caacttttcc gcttgttttt
     6841 tcttttcttg gatcgatttt tccaatcgtt ttttctcttt catgatcgac tctgcttctc
     6901 gtagctgagt ctttttctcc aattcctttt gagtgagata ggcactataa ttccccgaaa
     6961 actctcggat ttctccgtct tttacttccc agattttcga tgctagctca tctagaaaat
     7021 agcgatcatg actaacaaaa accagcgtac cataataata acgaagctct tcaatcagtc
     7081 gatcaatact ttttctatct agatgggttg ttggctcgtc tagaagcatc ccttgttcat
     7141 aagaagaaag aagacgtatc aactcgatct ttcgttcttc ccctccgctc catttccgct
     7201 ctgaagtttc ttccagtctt aactggaaat gactggctaa ttccaaattt aggtcctttg
     7261 cttcagcgag ataggttaat tgaggcaggt agttgaaggt gatctctgtt tggattttcc
     7321 catgatcggg aaaaagttca ccggctatta gtttgagcaa agtcgattta ccgacaccat
     7381 tttctcctat gatccctata cgatcttgct gatagacacg aagagaatca atagatagtt
     7441 ctagctggtt gccaaagctg acttgtagat ttgttatatt tactgctaaa ttttccatat
     7501 gttttacact cctatttcat gtaaaacaac aattatcgat actaaaaaag agcagaaaaa
     7561 tctgtttgca aaaaaactgc atcacatctt ttcctactct gaacgaaata actatgacta
     7621 aatcaccaaa tctgtcatag ctttcaccta ttctactgtc gttcgaaaaa atggacatac
     7681 tccatccatg aaattgttgt ttatacatgt cttttgaatt tatttagttg ttattcaaaa
     7741 gttcgaaacg taatttcatc gatgcagtca tttttccgac ctcctttttt attaggttac
     7801 cacacacgat tcaaaaaaag caatagctac tgaatagtaa ctgaaaacct tttattcgaa
     7861 cgtagtgatc ttttctggtg ctaaacgaac agactcgtaa ccttcttcta ccgcttttcc
     7921 tattgataaa ataataactg gaacataacg gtctttatcc aaaccaaatg cctctgccaa
     7981 ctgatctgct tcgactccac caattggatt tgtttcatag ccatgatcac gcgcaactaa
     8041 catgaattgc atagccgcta agctagaatc gactttgact acatcgttca tttcttctct
     8101 tgaaaaactc ttgtaataag gaatgatcgc agctaattgt tgatctctga cttcttttgg
     8161 catcttccct gattcgtaag cttggttata gatttcttcg ccatattcgt aacattgcat
     8221 atcgccaaaa atcatgacca ttgcagaaga agtatcattt tgtctcgtat tgaaacggat
     8281 caaaggacgc aagatttctt ttgcttcctc gctttcagcg accacaaagc gccatggttg
     8341 catattgaca gaagaaggtg cagtcgtcgc ttctttgatc atttccagca tttcttcgtg
     8401 tgggattttg tatgtttcat catatacgcg aacggatctt ctaccagtca taattgttga
     8461 aaaatcattt ttttgttcca ttattattaa cctctttcgt ttctgttgtt atattgcaaa
     8521 gttgggtatt caatttatct aaaagtgtta gaaattgttt catttctaca tcgctgaaag
     8581 ccggggatag cacggaacct gtatctttat ggtccatttc acaatgctcg attttcttct
     8641 gggctttttc tgttagcgct acatacactt cccggttgtt ctgaggattt ctctgacgcg
     8701 aaacatagcc atttgcttcc aataccttca gatgacgagt aactgctcct tgatcaatct
     8761 gcaacttttc ttgcaaactg ctttgtagca atggattttc ttctttcagt ctcatcatga
     8821 tctcgtatct agtaagactt ataccgatat tttcttcaaa gatctggacg attttttgat
     8881 cggctaattt gatttgatat aaaaggtgac taatctcttc taaagacata atttcctcct
     8941 ttctaataat tgactcgtca acgattgact tgtcaataat agaataaaaa aagaaaaaag
     9001 tcaaagaatc agctgtgtaa taaaaaaaac gctctcaata gaaaagtata gagaaaagaa
     9061 attttttgta gaatgaacgg aaaaaatgat aaagaaagca caacgctaaa accaagatta
     9121 ttgattctta tcaaactata gaagatagct cttctgcagt agaaaatttt acaccgccaa
     9181 aaatttccga aatcgccttt tgcaagaatc ccgtcgaata ttagaaattg gatcagtatg
     9241 cttaaacagt aataaaaaag ttatgacaag atgttgtcac aacctttttt gagtaaacgg
     9301 tgttcaaaaa cttgcatctg cggtaataag ttcaaccaaa caaaaaacat gaaaatctgt
     9361 ttttgtttgg ctgttcttac tacttgatgc agggcagctt tttcactacc tctttttaat
     9421 aaccataaaa tcctattcct tcatatctcc agcccatcgg tgttagccaa tctctttcct
     9481 tagcactcaa ggtatagtga tgggtaccag ttttttcatt tggattaaat agtcgataaa
     9541 ttggcttgga accaccagaa taaaaactta gaccttcata acgccaaccg atttttgtta
     9601 aagagttgat ctcagattgt gccattgtgt aatgatggtc tccactgtaa ggattgtata
     9661 aacggtagac aggttgtccg ctgtttggtg cttgccaagc aatcccttca tattcccagc
     9721 ctacagttgg cagataattt ttttctccgg cattcaatgt atataaatgt tctcctgtat
     9781 gacggttata cagacgatac atcggagaag ttgaagttgg tgctgtatca tactgtgtca
     9841 gattataggt ttcgattaca ttgttcaatg tagaaccata attaggcgca gtggcataac
     9901 gacctgttag ccaagccgta gcatctttgt aagagttcgt attgcttttc catgcaccgg
     9961 aatagtagta aacgcctggc tgaaaagaag tcgtcttcaa taccgttacg ttatcttgca
    10021 atgattcttt gtacgaagga tattttctaa aagcggcatt caccgtaatc cattgcccat
    10081 tcacatattc cgaagtaggc atcgtaacag attggccatt atagcttcct ttaatcccaa
    10141 atagattgta attaggggca gaagccaaag tactgttccc ccagccactt tcaacgatgg
    10201 cttgagcaat catgactgat gcatataagt cattggcact tgccaaactt tgtgcagttg
    10261 aggcaatact atcaatgaac gcttgttgag aattagcaga tgagcgagca taaaaagcat
    10321 agccagtata gttttcgaat tcagacaaat ctgcttgatg ggtatgtgtc aatgtttgcc
    10381 catctgtcaa ttggttcgtg atttcttctg cattctctgg attgttctga gcttctgctg
    10441 atgtactgtc ttcggtttgt gtttgttctg ttgtttcagt tgttggttct tcggttgaaa
    10501 ttgtattttc tgagacagta gctgactgca aagtactctc tgtatcgttt tcaattcctg
    10561 tttctgaaga actcgatgtc tgagttgcga cagtttctgt cgattcttca gctagcactg
    10621 ttgtgttggc aactgctaga tttcctaaaa gaataacgct aaataataaa ttctttgctt
    10681 tcatcttttt tctcctttga attatgaaac ttttcctaaa taacagtgta actaaaaaag
    10741 taaaagcaag tcaatgtcca tatttaaata acatttgttt ctttttgata aatttgcttt
    10801 ttctacataa aaagacgtaa atgaagaata ttcttctcca ttcacgcctt aaattgatgg
    10861 tcgtttgaat aactatttaa caagtaattc tctttggata ttatccgtta tggattatac
    10921 ttcctgtgtc gtcggacgga taatcatgtt actgacagac atccggtctg gcgtttctat
    10981 cgcaaatgct acagcagaag ctatatcttc ggaggtcaat ccccattctt tttgcgcttc
    11041 atgaagttca agagcagcct ttttgtcgct gatggtttga tataattcag tttgaacagc
    11101 tcctggagag atgatcgtag atttgatgtt attttgccgt tgctcttgac gtaatccttc
    11161 catgattgca cggacagcaa attttgttcc gcaataaacg gcggaatcag gataaacaac
    11221 atgtcccgcc acagaatcag ttgaaatgat atgcccagat ttttgttttt ccatgattgg
    11281 aagtacggcg gaaattccat ttaacacacc catgatgttg atatcaagca tattttgcca
    11341 ttcatcacgg tgaccttcaa ctaatggagc ggttggcatg attcctgcat tattgtacaa
    11401 tacatcgatt cgaccgaact tttccatcgc taaatcgata actgcttgga cttgtgcaaa
    11461 atctcttaca tctgctgttt gaatatatag ctcagcttct ggtaaagatt cttttattgc
    11521 ttttaggcga tcttctcggc gtgcagctat aactagttta gccccttttt ctgctaatag
    11581 cttcgttgtt gcttcaccga ttccgcttga agcgcccatg atgacaatca ctttttctga
    11641 taaatcattc attctattct cctcctgttt tgaaaaatct cttgcttata ctcactatct
    11701 cttatttcat cttactgttc aaataatccg ttcgacaggt ttgacgattt tggcagggat
    11761 tcctgcaacg atggtattgt ctgggacatc tttcgtaaca gttgcattcg ctgcaacaat
    11821 ggcattctcg ccaatcgtta cgcctggcag aatagttgct cctgctccga tccaagcatt
    11881 tttcttgatg tggattggct ttactaacaa gcctcttcgt tcttttggat cggttagatg
    11941 gttcaccgtg atgaggttga cacgaggacc aatcaatact gaatcttcta aacagatgcc
    12001 acctaagtca acgaacatca cttgacgatt gataaagaca tttttcccta tactaatatg
    12061 tttgccgaaa tctgtataaa aaggcagcag aacagtcacc gtatcatcta ctttgtcact
    12121 aatgatattt tctagccgtt tgcggatatc tgctggttca tggtacccag tattcagcgc
    12181 tgctaaaggc tcttcgtttt cagcttggat ctgatggatc acttcaaaga gcggatccgt
    12241 tactcgaatc tctttattga cgatttgttt ttcgatgagg cttgtcattt tgctccctcc
    12301 ttttatcctt actttataac ggacggctta tcatgtctaa tacttataaa acatacttaa
    12361 ctattccttt taactatact tagtggtatg cttttttaaa aacaggaggg aaaaaatgga
    12421 tattcgtata ctgacgtatt ttttagcagt agctagagaa aaaaatatca gccgagcagc
    12481 aaaatctctg catatcacgc aacctactct ctcaaaacaa ctgaaagatt tagaagaaga
    12541 acttggtgtg acacttttca ctcggggctc ccgagagata cagttgacgg attctggtcg
    12601 atatctttat tcaaaaggaa aagaaatctt gtcgttggta gaaaaaacgg cgaacaattt
    12661 aacaaatgac gcaatcatct ctggagaaat ctacattggc ggaggcgaaa ctaaagcaat
    12721 ctctttcatt tctgatagcc ttcattcgtt gatcaaggcg catcctgata tccagtttca
    12781 tttatatagc gggaatgcag atgatatcat agacaaactg gatagcggat tacttgattt
    12841 tggactcgta atcgaaccga caaacaaaca aaaataccag tcatttcgac tgccagccca
    12901 agatcgttgg ggacttttga tacatcgaaa tcatccttta gcaaagcaaa ccgtcatcca
    12961 tccgcaggaa ctgaaaactg ttcctttgat catttcccgg caaacgtcag tggacagtca
    13021 actagctgaa tggctaggtt tcagcataga tcagttatcg atcgtcggaa catataactt
    13081 attgtacaat gcttctttga tggtcgataa cgggactttt ggtgcattag ctctagatgg
    13141 gatcatcaat acttatggga cggaaaaaat attcatccca ctcgatccgc cattacaagc
    13201 ttcactgaat ctcatttgga aaaaagacca gcctctttct cctgctgctc gtaaattttt
    13261 agatgtccta acggagaaat acagttaagt agagtttttt tccttcgctt tcagcttttt
    13321 aacaacgaat aagataagca aaagatccaa cgattaaata acataagttt cttaatttat
    13381 ttcttccttt tatttctgat aattccagta aattactata attataaaaa aagaattgac
    13441 aaaacataac tgtctatata aaattgatta cgttaacaat aattcgtttc atgtgactag
    13501 atcatactag gcatgaaaaa tctctgagga acatggtttc cctaggaggt ttttcgtgtc
    13561 tatttttgtt tggccgcaat caactggtct agcaaacgtg aaaaccaaat cttcaaaaag
    13621 ggtgcgcgca tgaaaatcaa aaagatcttt aatcaaaatg cagtattggt agatgacggt
    13681 ggacaggaaa aagtagctat tggaaaaggg attggatttg acagaaaaag aaatgatttg
    13741 atttttgatc gtgatgtcga acggatattt gtcatggaac cagaaggtca aatcaagttg
    13801 caaaatttac ttaatcagat tgatgaacgc tttttatttg cagcagaaac gatcattgat
    13861 catgcggaaa ctgttttgat ggaaaagttg aatgaacatg tattgatcgc tttgaccgac
    13921 cacattgctt tttctgcgga gaacattaat aacggtatcg tcatccgcaa caaactttta
    13981 agagaaatcg aagtgcttta cagtgatgaa ttcagtattg ctcaatgggc agtagagtat
    14041 ctgacaaaag agcttgggat tccatatact tatgacgaag caggatatat cgcaatccat
    14101 attcacagcg gacgaagcgg tcggaacaat aaccatcgca gtatccgtga agtgacgatt
    14161 gtatctgaca tcatccattt agtggaatca gaattggaaa cagatatcca ttcagaacca
    14221 ttttcactga attattcaag actggtgaat catttacgac tgcttctaca acgaacccat
    14281 gcgcaacaat atgctgtttt agacacggaa atcgtagaaa tggtcaaacg aaaataccca
    14341 gaaagctata agatttctaa aaaaatccgt gtgttgctga ccaaagaata ccagctcgcg
    14401 atcacgaaag aagaactggg ttacttggcc atccatatcg agcgtttaag aagcgcaatc
    14461 gtacaaacaa atgttaacaa tcatgaggag gaaaaaaatt gaaagcatat ctacaacgaa
    14521 tgggacgttc ccttcaactt ccagttgcgg tcttacctgc tgctgcttta ctagtaggga
    14581 tcggaaactg gtgggcatct tatagtaacg acattgtcgc tcatttttta caagctggcg
    14641 gtaacgcagt tttaggtcaa ttacctttgc tgtttgccgt tgggttagca ctagggatgt
    14701 cagtggacaa atcaggtgct gctgccttgg caggtttggt cgcatttgaa gttccagtaa
    14761 atgttttaaa aactgattca gtagctactt tattgaatat caaaccagaa tcagttgatc
    14821 catcttttgc tcagatcagt aacgtattta ttggtattat tgccggattg attgcggcag
    14881 ctctttataa tcgtttccac gaagcaaaat taccgatggc tttatctttc tttagcggca
    14941 agcgtctagt gccaatcttg gctgcctttg tcatgttgct gatcagtgca gtgctactgc
    15001 tcgtatggcc tccggtttac tctgctttag tttcttttgc taaattcatt ttgagtttag
    15061 gctggggtgg tgcaggtctt tatggcttct tcaaccgttt actgatccct acaggattgc
    15121 atcaagcaat gaactccgtg ttctggtttg acgtagcagg aatcaatgat attggtaaat
    15181 ttttggcttc tgaaggaaca aaaggcgtaa caggaatgta tcaagctgga tttttcccaa
    15241 tcatgatgtt cgggcttcca gcaggagcat atgctattta cagaaatgca cgtccagaaa
    15301 acaaagcaaa aacagcttcc ttgatgctag cagcagcttt tgcttcattc tttactggtg
    15361 tgacagaacc acttgaattt tcatttatgt tcgttgcttg gccattatat gtcttgcatg
    15421 caattttcac tgggatttct ttagcagtga gtgcattctt ccattggaca gcaggatttg
    15481 cctttagtgc cggatttgtc gattacttcc tatctttgaa aaatccgatt gcgaatcagc
    15541 cattgatgtt gatcgtccaa ggattagtaa cagcagtgat ttactacttt ggctttaact
    15601 ttgctatcaa aaaattccat ctgatgactc ctggccgcga ggaagcagat ctttcagatg
    15661 acgatactgc aacgactaat tcagacaata aatatgcggc acaagcaagc aaaatctacg
    15721 ctgcattagg cggagccgac aatgtaactt cgatcgataa ctgtactaca cgccttcgtt
    15781 tgcaagtcaa agatacaggc ctgatcgatc aaaataaaat caaagccact ggcgtacctg
    15841 gtatgaagat catcgacgga aaaaatgcgc aagtcatcgt aggtacagaa gtacaattcg
    15901 ttgcagatga gatggcaaaa ctacatggtg gtgctgcagc acgacctgca caaacaaaca
    15961 ccgtggttaa aacagaaaca tttgccggtg aaacgatcga acaagatatt tacgctatcg
    16021 caaatgggaa actgattcca atcactgaag tttcagatga tgtattcgcg gaaaaaatga
    16081 tgggtgacgg ctatgctgta ttaccagaaa atggagaaat cttctctcca atcgctggta
    16141 cgatcacaaa cattttccca acgaaacatg ctgtcggaat ccaaacagat gctggtatcg
    16201 aagtcttgct tcatatgggc atcaacactg ttgacttaaa aggcgaacca ttcactttat
    16261 atgtagaaga aggtcaaaaa gtcgcaagag gtcaattgat tgctttagtt gatcttgccg
    16321 ctattcaatc tgcaggcaaa aacacggata tggtcgttgt attcacaaat ggcgacaaag
    16381 tccaaagctt agaaatcgaa cccgcacgtg atgtaaaagc aaatgataaa atcggctctg
    16441 tttccaacaa agcctgagcc atcgtcttcc ccagactttt ttatcgataa acaaacagga
    16501 gctgagacaa aaatcttgtc tcagctcctt tttccgaata aaaacggcgt tctcctgcca
    16561 actccgcggt aataagtcca gctaaacgaa acatatgaag agctattttt tatttgactc
    16621 ttcttattac ttgatgcaga acagcttttt cacaaaattt ttcttcatac tcaaaactaa
    16681 tcggcttttt cacaacctct ttatacatta ttcctgatcc aatatttctt ttaatgctgc
    16741 ttcaagagaa gttaatggtt ttcccaatac tttttctaaa tcatcagagg aaatagctaa
    16801 ctgatccttt ttaatatcat gttggatcgc taaaaacatg tcagctgctt cttgagggaa
    16861 tccggcttct tttagatttt cgacaaacgc tgcatcactt gcttcaataa tttctaactc
    16921 tttacctgtc gcacgctcta atgccttggc taattcttca tagtcagtta gattgccgga
    16981 taattctaag atttctggag agtcactttc tactagtact tttgctgcag cttctgcata
    17041 ttcacgtttc aatgcccaac ctgtttttcc atttcctgca gcataaacga attgaccagt
    17101 ttttaaagcc tgcccaatga taggtaattc attctctaca taccaattat tccgtaaaaa
    17161 tgtatgggaa atacctgaat ccttaatcat tttttcagtg aattggtgat ctggcgctaa
    17221 tacactgatc gagtgatcgg catctgcaaa acttgtataa gcgatataag ataccccagc
    17281 tgcttgtgct gccttcacta cattcttatg ttcggcttga cgatttcctg gaacgccaga
    17341 gacaaaaagc aatcgatcta ttcctttcaa cgcttctttc attgagtcta aatcatcata
    17401 atcaccaata cgtatattaa atccagcttc tttcagtgct tctccttttt cttcactacg
    17461 tactagtaca tagatttcat tttgtggaac catctttttt aagaattcca gcgcataacc
    17521 accaaaacct ccagttgctc ctgttactaa ataatgcata tttgccactc cctattcttt
    17581 ttatttgtta agatttacag ctgtacattt ataaattaca cctttatcat aaagagtgtg
    17641 gtaagataag tcaagcaaaa aaaatgaaag gatgacaact gatgaagtat tctctgcaat
    17701 ttagtgatgc aatccatgta cttgcctata ttgaaatgtt tcaagatacc cgatcacttt
    17761 ctagtgagat gattgccagt agtatcgaaa caaatgcagc aaatgtacgt aaaatcatga
    17821 gtcagctcaa aaaatccggt ttgatcttta caaaaaccgg aaaaccgcag ccttcccttg
    17881 ccaaaagtcc agatcagatt tctttactag atgtctatcg cagcatcgaa ggtaatacac
    17941 agcttatcca agtcgatcca aaaacaaatc caaattgcgt cgttggtgcg aatatccaag
    18001 aagctttaga agaaagctac gctcggctgc agaaaaaggc agaagaagaa atggctaaga
    18061 tcacacttga tagtctgata cataaaatag ccgttttgga aaaagaaaaa agaccagaaa
    18121 acacaggcct cgtagagaga tttttataat tctctctact gtgcctgcat ttttctgatc
    18181 ggaatcgtct acataaattc ttttattctc cgggggacaa aagccttgtc atgccccttt
    18241 ttcctctcta atgctcaggt caaagcgctg aagtcatgac gtcttgataa acggtgttca
    18301 agtagctgac cctcggcatt agttctgaaa aatgcaaaat atggaaagct atttcccatt
    18361 tttcctctct aatgctcagg tcaaagcgct actttcacga cctctatatt atcatggttt
    18421 attgactacc ggtatccaga tttctcccat atatttcccg ttggtaactc ccatttcgac
    18481 tacagcattt ggacccccaa cataggcgta atcttctact tctcttaaaa catgcccaaa
    18541 ggccgtattc gtcaaatcat ttcttaattc ttcaggcgat tctgctaaag cgcttacaac
    18601 aagatacgtt ccttttggga atgggatgat tcgcgtagtg tttggaacat cctgactcgt
    18661 ttgaacaccg acatagtaca tcattttccc gttatagggt tcgttgactg taaagaaata
    18721 atgattttca gcagcttgtt tcaatgcatc tattgttcca ttaccgataa ctttttgctc
    18781 aaatgcttgt ttctctgcag ccaaaccgac aaaatccgta ttgctactct tcaattccac
    18841 accaataccc gtcaccgtaa aatctggttt ttcttcgatc ctatactttg ccatttctcc
    18901 caccctttct attatattaa gttcatctta cataaaatta aagggaaatg acacgattac
    18961 gctctttttt ctagggatat ttttattttt taactatttt tttgctttca ctgcaatcca
    19021 aatctcactg taaacattac tgaaatcctc tccccatttt gtaaaagaga tctcgggagc
    19081 ttcgactaac ccataatctg aagaaggaag ccattctgca tagattttcc cccaagtatc
    19141 ttgtaaagtt tggggaaatg gccctttatt aggaaaaatg gcccaagtgt gttcttctat
    19201 agcaagcatt tctaaatcag cgtacggatt ttcttttgtc gtagcaaagc caatcatgtg
    19261 catcaaactg cccttttctt ccaagcggtc tccatcaaat ccataagaaa cgttgattac
    19321 ttgatttgga tataaatctc ctaacttatg catctcttcc ctttgagtct ccgtgatcgt
    19381 ctgcgctaac ttttgtattt cttgattgac tccttcaaat ttgacaggaa cttttttcgc
    19441 cacacctgcc acataaaact gttctttctt ttcgatacga aattccatcg attttcctcc
    19501 tctgacatca ataaaaaatg tcaagcgtgg aaaagatttt tgtatgccgt atctgctgat
    19561 ttctgaaggc agatatcctg accaatcacg aaaagctctt gaaaaacctt cgactgtttc
    19621 atatccatat ctaaacgccg tttctgtcac tcttgatcca tctagaagat cgcgattagc
    19681 caaagccaat ctacggtttt tgatatagtc cattagcgac atccctgcaa taaacgtaaa
    19741 gatgcgtttt aattgatatt cagagattcc tgtattttcg gctattattt tataggaaag
    19801 tccttctgtc aaatgttctt cgatgtaatc gatcaattgg ttcagatctt taagcatatt
    19861 tatcttcctc cttgattgcc tttttatcat attatcaaag aaagtcaatt acttgatgaa
    19921 tcaggaacca atttagtcag atgtagaaaa tgttgtatgg atctaaagaa aattctcaag
    19981 cagcgtttcg taacggataa ttggtattat ctgcctatct atgttttacc tttagaaaaa
    20041 taaattttgg ggaagacaga ttctaagtaa acaaagcggt aaaaatatct tttattccct
    20101 tagttaatcc gcttactacc tactgtacaa agcaaattgt tgttcaaact gctgatcaga
    20161 acgctgcttg gatttttctt t
//
LOCUS       DAZUJR010000054        20143 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.054, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000054 DAZUJR010000000
VERSION     DAZUJR010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20143
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.054"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            133..636
                     /locus_tag="ACG804_001857"
     CDS             133..636
                     /locus_tag="ACG804_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HFS4832786.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKEQIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCNLAEELEGTPIGEAASEIQHAFFNSFEEMVEH
                     VDDIVYYPDCDDMSDVAHYLIVEAGDFGEVPEQLKPYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPE"
     gene            763..1800
                     /locus_tag="ACG804_001858"
     CDS             763..1800
                     /locus_tag="ACG804_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic GMP-AMP synthase DncV-like
                     nucleotidyltransferase"
                     /protein_id="HFS4832787.1"
                     /translation="MANIQTSFIDFHNSIRLDVEDNTLLKDYKDQVIDGLKDYLPDDV
                     KFETFLQGSYSVYTGIKSCDEKIDFDIDIAVAFEIDHTVYEDPREPKLWVKEALVEIF
                     PNAQVNLKVPCVTATFTGKKTKKNVHVDVAVYAKEDENYFLAKAKEFSAPENRCWEEA
                     DPKVLKEKINSHVADSDDRKQFRRCIRYLKRWKDNNFNQEYKPTGIGLTINVMDTFLV
                     NKSTDFLTRKVQYNDMECMKQIVSSLKDSFVYEYSETDGWHYRLHAYLPVKPNSDTYS
                     KMTVNQMSDFKNKLSKLYDDLIFAIDTEDEYEATKRLNNQFGEDFLIISEEEVTEKNL
                     RNAFVTDYPSA"
     gene            1815..3512
                     /locus_tag="ACG804_001859"
     CDS             1815..3512
                     /locus_tag="ACG804_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="E2/UBC family protein"
                     /protein_id="HFS4832788.1"
                     /translation="MDYTDILKEKLTDVVRLFDGNYYGDFSFATIGKLRLKIEIPKHF
                     PLVLPRIYIHNFDHLGLYLPHVEKDGLVCFSSDINYLVDEENSELVLLQCVNKTIKTI
                     EEGLKGLNKNDFRKEFVAFWDKQENQISLFYLCEPALFIKSVDTIMYGKSLVALDKEN
                     ELQLNAASRLFNGEKEDTHELDAYYVPIRNKNNIMPPKNNKAWSKKDILQIVKKNVTG
                     ANKRFFLKLEKRKNRHNVLLILDIPIEEKSNNVIIGFLFTKQSGSIKDYKGTPRTVLV
                     QRHDELYLVNRTSGENYGLGANIAIVGVGSVGSKIAENLGPLGVRKMTLIDNDCFQAE
                     NLYRNSLGADSLKNARSQNNFFKVDLMQEELEKKIPYLCVEVESMNVLDLISMQPGFF
                     KEYDYVFVCIGDTMASLALNNYFSKSSQKVFYSWLEPYGIGGHTLFINYSLNQKGCFN
                     CLYTDSNSKNRCSNRASLVKEGQIFERTLASCRSKFIPYNAIASTECAINAIKLFHKV
                     NQNNMTNSTLFSWIGDGSTFENLGYQYSDRNTFLNGVNKFEERFFSKYCKVCGELDD"
     gene            3505..3966
                     /locus_tag="ACG804_001860"
     CDS             3505..3966
                     /locus_tag="ACG804_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mov34/MPN/PAD-1 family protein"
                     /protein_id="HFS4832789.1"
                     /translation="MIKFSCDRIVIEVRDEVLKIFEQYRQGKDDLPEAGGVLHGKRLK
                     NGSIIITDITTPQIGDIQKRLLFKKNREIHQQLSNEKWIESNKFSIALGEWHTHPEAV
                     PTPSNVDKKSWRLNVSKQHDDRVYVFIIVGFSDLRMWLLSKKSDIRQAIKL"
     gene            3979..4839
                     /locus_tag="ACG804_001861"
     CDS             3979..4839
                     /locus_tag="ACG804_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832790.1"
                     /translation="MKSQKNIWWWGFLVGKVMIPALLLISLPMITFFFTNKKMSKEAV
                     IFFFGDQKATFIETLVTSLQLNLNYIFSIIIVISLLNFFKKRNSGKVFNSNGNVYYNY
                     FYFVFWVAATLLGYDKIQIAGIPIHMQYKLVLSGIFSEVLPDIYDDHYDSDGTCKVSI
                     EKENFDDIDGYDSVNLLIIDTYDIKMSELSMENQTYPTIIVRGNSIDGVRKVNRSLIL
                     EIKKTMDEIQKSDFKKVFVASTSNPKNSINIINSSFRFFGRSRRFKLYVLQKDYASNG
                     KYSKKYRIFI"
     gene            4877..5266
                     /locus_tag="ACG804_001862"
     CDS             4877..5266
                     /locus_tag="ACG804_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFS4832791.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLMFV
                     IVFAHVPPLSMIEGAFLKYLGIPIAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            5253..7700
                     /locus_tag="ACG804_001863"
     CDS             5253..7700
                     /locus_tag="ACG804_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFS4832792.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDLQTDALVSMI
                     GDSQIDYRFFIGFKLISTDEEVNLKNLRKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVKRVTPSDLTYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPTRCLIEEKPRYLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAKSVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HKEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALASAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVIVELRKEDSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDKEDESNQKCMRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            7705..9813
                     /locus_tag="ACG804_001864"
     CDS             7705..9813
                     /locus_tag="ACG804_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HFS4832793.1"
                     /translation="MKKKLFRIFGIVLISLVTLIILLSLVGTVAEATGLVDDTVGAGN
                     LYSQYSLGNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEVGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMNMFNLQSNDSQSMGRRVMRKPQMLMNRTLR
                     QLNRNVGRTLAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEIPSDLNKEK
                     PIPNNKKQSRMNLAGRKVGKVLDTQALVKDKTKQVKDGVRNTPTNLKYNFHKGIEKTK
                     KAPEEFKRGLVQEKANRGELREKQQQRRDEKIAEKRKVLNEIGNPHGKRRENVPIKAK
                     VQSQKDRAPKRIVRANSNPEIKRKFASQEIISKGINQSSSKKNSFQQVKRRSTLSKRT
                     NRKVQKSLNPHPKPRSGEKK"
     gene            9810..10814
                     /locus_tag="ACG804_001865"
     CDS             9810..10814
                     /locus_tag="ACG804_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HFS4832794.1"
                     /translation="MNVKKLSAISLTFLTISFMGILMCVGLLFGEDSEGSSSSGAPPG
                     GSSVSEEVLKHRAMVEKYAKESDITEYVPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNFGGGYLDYVAKNGKKHSFALA
                     ESFSKEKSCGQKIDYPNPIANKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSRPETGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTESYWQQHLIGAGRYK
                     "
     gene            10833..11744
                     /locus_tag="ACG804_001866"
     CDS             10833..11744
                     /locus_tag="ACG804_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFS4832795.1"
                     /translation="MKIKIERNQKEKSLKKKKERVVSVGKHRKMVLALWLLLSCSLTF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGIENFTKDFSKEYFSWKNNKEAIEKRMNNL
                     EQYLTEEGFALSQDMVRADIPTNSEVQSVKVLDVEKSSEEFVVSFLVEQKITEGKKAQ
                     SISSAYRVTIFEDENRNYIVTSLPTMIAKPDRAKYKTKQVENDSKIDAKTTEEIAEFL
                     ETFFKLYPSASEKELEYYVENDAMRPINIDLKFSKLEDPVYLQNGKKILVSTKIKYLD
                     NVSKTTSYFQYKLILQKNGNWKIIDVK"
     gene            11931..12218
                     /locus_tag="ACG804_001867"
                     /pseudo
     CDS             11931..12218
                     /locus_tag="ACG804_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(12406..12621)
                     /locus_tag="ACG804_001868"
     CDS             complement(12406..12621)
                     /locus_tag="ACG804_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832796.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(12880..13089)
                     /locus_tag="ACG804_001869"
                     /pseudo
     CDS             complement(12880..13089)
                     /locus_tag="ACG804_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
     gene            complement(13392..14831)
                     /locus_tag="ACG804_001870"
                     /pseudo
     CDS             complement(13392..14831)
                     /locus_tag="ACG804_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(15379..16050)
                     /locus_tag="ACG804_001871"
     CDS             complement(15379..16050)
                     /locus_tag="ACG804_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HFS4832797.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRYLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCQCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEKWIAYITLK
                     KRGTI"
     gene            complement(16399..17850)
                     /locus_tag="ACG804_001872"
     CDS             complement(16399..17850)
                     /locus_tag="ACG804_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFS4832798.1"
                     /translation="MKKSLKLASAVILMSQLFIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTLSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSAESSTTSSSTSEITSSKVTRPNHIESSKKEAPKTEGQTKNFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            complement(17962..19305)
                     /locus_tag="ACG804_001873"
     CDS             complement(17962..19305)
                     /locus_tag="ACG804_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFS4832799.1"
                     /translation="MKKIVIIGSNHSGLAAARFLNLCDSNYEVILIDKKSEISYLECG
                     TSLFIKREVSNLEDLFYQNRRELNSKIKKLFLETAVDKIDIQNKKIICVKKDGTRFSQ
                     EYDKLILATGSKQIMLDVPGNNLANIFSIKNFPNAKEIFKALDDNTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGKKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHIDNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPVFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
     gene            complement(19439..>20143)
                     /locus_tag="ACG804_001874"
     CDS             complement(19439..>20143)
                     /locus_tag="ACG804_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rib/alpha-like domain-containing protein"
                     /protein_id="HFS4832800.1"
                     /translation="DADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKV
                     DVSTAGNKKGIVVVTYPDGSKEEVEVTISVEDKKAPNKPQVDPITEGDQIVTGKTEPN
                     AEVTVTLPNGSQYHGTADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSN
                     EKDSEKAVSKDNKTDNQGSKQNKNRGKSSPQKQSSKAYPKTGEIDSNIFTISGGLILL
                     GTLGLLGYKNRKKENE"
BASE COUNT         6501 a         3417 c         3746 g         6479 t
ORIGIN      
        1 gagttttcca aactgattgg cttcttggtg attgctttga ttgcggtagg tctggtcttt
       61 aatgcttctg gtgtgaagga tgtcctactc aatttgttta accgaattgt cggtgcctga
      121 gggggaatca caatggaaca gatgcgtgtt tatattgcga accttggaaa atacaatgaa
      181 ggtgagttgg tgggggcatg gtttacccca cctgtcgatt ttgatgaagt gaaagaacag
      241 attggattaa atgacgaata tgaagagtac gcgattcatg attatgaact gccttttgag
      301 attgatgagt atacgccaat tgaagagatt aatcggttgt gtaacttagc ggaggaacta
      361 gaaggaacgc caattggtga agctgcttct gagattcaac acgctttctt caattctttc
      421 gaggaaatgg tagagcatgt ggatgatatt gtctattatc cagattgcga tgatatgagt
      481 gatgtggcgc attacttgat tgtagaagct ggtgattttg gcgaagttcc agaacaattg
      541 aagccgtata ttgattttga tgcttgcggt cgagatttgg agattggagg aaattatttg
      601 gttactagtc gtggagtttt tgagtatcca gaatgaatca aacactatat atagtgtttg
      661 attagtatat gtaagcaaaa aaacacaata tatagagtgc aaactgaagg gtaatgtgat
      721 ataatatttg ccgaagaaat atttttgaaa tgaggtaata ttatggcaaa tattcaaaca
      781 agttttattg atttccataa ttcaattaga ttggacgtag aagacaatac gctacttaag
      841 gactataaag accaagtaat tgatggatta aaagattact tacctgatga tgtgaagttt
      901 gaaacttttt tacagggaag ctattctgtt tataccggaa taaaaagctg tgatgaaaaa
      961 attgattttg acatcgatat tgcagttgct ttcgaaattg atcatactgt ttatgaagat
     1021 ccaagggagc ctaaactgtg ggtaaaagag gcgctagttg aaatttttcc taatgctcaa
     1081 gttaatttaa aagtaccttg tgtaactgct acatttactg gaaaaaagac aaaaaaaaat
     1141 gtgcacgttg atgttgcggt ttatgctaaa gaagatgaaa attatttctt agcaaaagca
     1201 aaagaattca gtgctcccga aaaccgatgc tgggaggaag cggatcccaa agtattaaaa
     1261 gagaaaatta atagtcatgt agcagattca gatgatcgaa aacaatttcg aagatgtatt
     1321 cgctatttaa aaagatggaa agataacaat tttaaccaag aatataaacc aacaggaatt
     1381 ggacttacaa ttaatgtgat ggatacgttc ctagttaata agtccactga ttttttaact
     1441 agaaaagttc agtataatga tatggaatgt atgaagcaga ttgtttcttc gctgaaagat
     1501 tcatttgtgt atgagtacag tgaaacagat ggttggcatt atcgtctaca tgcatatctt
     1561 ccagtgaagc ctaacagtga cacctattca aaaatgacag tgaatcagat gagtgatttt
     1621 aaaaacaaac tttctaaatt atatgatgat ttgattttcg ctatcgatac tgaagatgag
     1681 tatgaagcta caaaacgatt aaataatcaa tttggggagg attttttaat tatttcagaa
     1741 gaagaagtta cagaaaaaaa cttaagaaat gcatttgtta cagactatcc gagtgcttag
     1801 gttggtgtta aagattggat tatactgata ttttaaaaga aaagctaaca gatgttgtgc
     1861 gtttattcga tggtaattac tatggggatt tttcatttgc tacaattgga aagttgcgtt
     1921 taaaaattga aataccaaaa cattttccat tggtacttcc taggatttac attcataatt
     1981 ttgatcattt aggactttac ctaccacatg tagaaaaaga tgggttggta tgtttttctt
     2041 cagatataaa ttatttagta gatgaagaaa attcagaatt ggttttattg cagtgtgtta
     2101 ataaaactat aaaaacaatt gaggaaggtt tgaaagggtt aaataaaaat gattttcgaa
     2161 aagagtttgt tgctttttgg gacaaacaag agaatcaaat ttcgttattc tacctttgtg
     2221 aaccagcgtt gtttatcaag tcagttgata caataatgta cggtaagtct ttggttgctt
     2281 tggataaaga gaacgaatta caattaaatg cagcgagtag attgtttaat ggagagaaag
     2341 aagatactca tgaattagat gcatactatg ttccaattag aaacaagaat aatattatgc
     2401 ccccgaagaa taataaagca tggtcaaaga aggatatttt acaaatagta aaaaaaaatg
     2461 taacaggtgc aaataaaaga ttttttttaa aacttgaaaa aagaaagaat agacataatg
     2521 ttttacttat tctagatatc ccaattgaag aaaagtcaaa taatgtcata attggatttc
     2581 tttttacaaa acaatctgga tctataaaag attataaggg tacgcctagg actgtattag
     2641 ttcagcgtca tgatgaatta tatttggtga atagaacgag cggagaaaac tatggattgg
     2701 gtgctaatat agctattgtt ggggtagggt cagttggcag taaaattgct gaaaatcttg
     2761 gtccattagg tgtgagaaag atgacactca tagacaatga ttgttttcaa gctgaaaatt
     2821 tgtatcgaaa ttcacttggt gcagatagtt taaaaaatgc ccgatctcag aataattttt
     2881 ttaaagttga tttaatgcag gaggagctcg aaaaaaaaat cccatacctt tgtgttgaag
     2941 tggagtcaat gaacgtttta gacttaatta gtatgcaacc tggttttttc aaggaatatg
     3001 actatgtttt tgtttgcata ggagatacaa tggcaagcct ggctttaaat aattattttt
     3061 ccaaaagtag tcaaaaagtt ttctattctt ggctggagcc atatggcatt gggggacaca
     3121 ctctatttat aaattattct ctaaatcaaa aaggttgttt caattgtctt tatacagatt
     3181 caaactctaa aaataggtgt tcaaatagag cttctctggt aaaagaagga caaatttttg
     3241 aaaggacttt agcgagttgc cgctcaaaat ttataccata taatgctatt gcctcgacgg
     3301 aatgtgcaat taatgcaata aaacttttcc ataaagtcaa tcaaaataat atgaccaata
     3361 gtactctttt ttcatggata ggagatggga gtacttttga gaatttagga tatcaatata
     3421 gcgacagaaa tacttttctt aatggagtca ataagtttga agaaagattc ttttctaaat
     3481 attgcaaagt atgtggggag ttagatgatt aaattttcgt gtgaccgtat tgtcattgaa
     3541 gtaagggatg aagttcttaa gatatttgaa caatatcggc agggaaagga tgacttgcct
     3601 gaagctggag gagttcttca tggaaaaaga cttaagaatg ggagcataat aattaccgat
     3661 ataacaacac ctcaaatagg agatatacaa aaaagattac tctttaaaaa aaaccgagaa
     3721 attcatcaac agctttctaa tgagaaatgg atagaatcaa ataagttttc tattgcattg
     3781 ggagaatggc atactcatcc tgaagctgta ccaactccat caaatgttga taagaaaagc
     3841 tggagactga acgtgagcaa gcaacatgat gatagagttt atgtttttat tatcgttgga
     3901 ttttctgatt tgagaatgtg gttactgtca aaaaaatcag atattaggca ggctataaaa
     3961 ctataaagga gtgattaggt gaaatcacaa aagaatattt ggtggtgggg gtttttagta
     4021 ggaaaggtaa tgataccagc ccttctctta atttctctac cgatgattac ttttttcttt
     4081 accaataaaa aaatgagtaa agaagccgtg atttttttct ttggagacca aaaagctacc
     4141 tttattgaaa cgttagtaac atctcttcag cttaatttga attacatttt ttcaattatt
     4201 attgttatat cgttattgaa tttttttaaa aaaagaaatt caggaaaggt gtttaactct
     4261 aatggaaatg tgtactacaa ctatttttat tttgtatttt gggtagcagc aactttactt
     4321 ggttatgata aaattcagat tgcaggaatt cctatacaca tgcaatataa gttggttttg
     4381 agtggaattt tttctgaggt gttgccagat atatacgatg atcattacga cagtgatgga
     4441 acatgtaaag taagcattga aaaagaaaat ttcgatgaca tcgatggata tgactctgtg
     4501 aacttactga ttattgatac ttacgatata aaaatgagtg aattatctat ggaaaatcaa
     4561 acatatccta cgataattgt tagagggaat tcaatagatg gagttcgtaa agttaataga
     4621 tctttaatct tggaaataaa aaaaacaatg gatgaaattc aaaaaagtga ctttaaaaaa
     4681 gtatttgttg cttcaacatc taatccaaaa aatagtatca atattattaa ttcatcgttt
     4741 agatttttcg gtcgatcacg taggtttaaa ctttatgttc ttcaaaagga ttatgcaagc
     4801 aatggaaagt atagtaagaa atatagaatt tttatttaag aaggaatttt tccttctttt
     4861 tattttggag gaaactatga aaaaaataaa aagctacacc agtatttggg cagttgaaaa
     4921 agtcatttat gcgattaatg actttcagct gccttttcct gtgaccttta accagatggc
     4981 ttggtttgtt ttatccttga tgtttgtcat tgtatttgcc catgtgcctc cgctatccat
     5041 gatagagggg gcttttttaa aatacttggg cattccgata gcggtcactt ggttcatgtc
     5101 gcaaaagacc tttgacggta agaaaccatt gggattttta cgatccttta tcagctatca
     5161 cttacggttt aaggtcactt ttgcaggaaa gaaagttaaa gaacagaaga aacgatggga
     5221 cgaaccaatc accttggtaa ggagtgtgaa ttatgtaccc gattaagtat attgaaaata
     5281 atcttgtctt taaccaagaa ggcgagtgtt ttgcttacta tgaattagtg ccttacaatt
     5341 actccttttt gtcacctgaa cagaagtatc aagtacatga taactttcgc caattaattg
     5401 cgcaaaatcg tgaaggtaag atccatgcct tacaaattgc cacagaaagt agtattcgtg
     5461 ccacacaaga acgttcgaaa aaggaaatta ccggtagact caaagaagta gcaaagcaac
     5521 gaattgattt acagacagat gcattagtat ccatgattgg cgatagtcag attgattatc
     5581 gcttctttat tggctttaaa ctgatttcga cagatgaaga ggtcaatcta aagaatctca
     5641 ggaaatcttt cttttctgga cttcaagaat ttgtctatgg agtgaatcat catttgatgg
     5701 gtgattttgt ttccttatcc aatgaagaaa ttcgtcgcta taccaagctt gaaaaactaa
     5761 tggaaagtaa attggctcga agatttaaag tcaaacgagt aacgccgagt gacttgacgt
     5821 atttaattga acatatctat ggtgaaaaag gcacaccgtt tgaagaatat gaattccagc
     5881 taccaaagaa aaagctgaaa tcagaaacgc tggtgaaacg ttacgactta ttacgtccca
     5941 ctcgttgttt gattgaagaa aagcctcggt acttacggat ggaacatgaa aatcatgagt
     6001 cttatgtagc gtacttaaca attaatacca ttgtagggga aatggagttt ccttcctcgg
     6061 aacttttcta ttaccagcaa caacaattta cgtttccgat tgatacttca atgaatgtgg
     6121 aaattgtgac gaataaaaag gccctagcta ccgttcgtaa taagaaaaag gaattaaaag
     6181 atttagacaa ccatgcctat caatctgata atgaaacgaa ctccaatgta ttagatgctt
     6241 tggattccgt ggatgaattg gaaaccacct tggatcagtc gaaagaatcc atgtataaac
     6301 taagctatgt ggttcgagtg agtgctaaat cagtggatga attaaaacgc cgctgtgatg
     6361 aagtgctcga tttttatgac gataccaatg taaaactagt ccggcccttt ggcgatatga
     6421 tgggtctaca caaagaattc ttaccctcaa gtaagcgata catgaatgac tatattcaat
     6481 atgttacgtc tgactttttg gcgggacttg gttttggggc tactcaaatg ctaggagaat
     6541 tagaaggcat ttactttggc tataacgtag atacggggcg caatgtttac ctgaaaccgg
     6601 cattggcatc acaaggggtc aaaggctcag taaccaatgc tttggcatct gctttccttg
     6661 gttcgttagg tggggggaaa tcttttagca acaatctctt agtctattat gccgtccttt
     6721 ttggtgggca agctgtgatt gtcgatccaa aaggagaaag aggcggttgg aaagaaacgt
     6781 tgccagaaat tgcggatgaa attaatattc ttaacttgac cagtaagcca gaaaatcaag
     6841 gcttacttga tccctatgtg attatgaaga aaaagaaaga ctcagaaagt ttggcgattg
     6901 atatcctgac ctttttaaca gggatttcca gtcgggatgg ggagaagttc cctgtgttac
     6961 gcaaagccat tcgaacggtt acccaaagtg atcagcgagg attattacaa gtaatcgttg
     7021 aattgcgtaa agaggactca ccagtcgcgg aaaatatcgc ggatcacatc gagtccttta
     7081 ccgattatga ttttgcccat ttgcttttct cagatggttc gattacccag tcgattagtt
     7141 tagataagca gttaaatatc attcaagtag cggatttggt tttaccagat gcagaaacca
     7201 cttttgaaga atataccacc atggaattgc tgagtgtttc catgctaatt gttatttcca
     7261 cttttgcctt ggactttatc catagcaacc gagaaatttt caagattgtg gacctggatg
     7321 aggcttggag ttttcttcaa gtagctcaag gaaaaacgtt atcgaataaa ttagtgcgtg
     7381 ctggtcgggc catgaatgcc ggtgtttact tcgtcacgca aaacagtgat gacttgttgg
     7441 atgaacgttt gaagaataat attgggctaa agtttgcatt tcgcagtacc gatattcatg
     7501 aaatcaagaa aaccttggaa ttctttggat tagataaaga agatgaaagt aatcaaaaat
     7561 gcatgcgaga tttggaaaat gggcaatgct tgatgcagga tttgtatggt cgagtaggtg
     7621 tggtccaagt tcatccagtc tttgaagaac ttttccatgc ttttgatacc cgtccgccag
     7681 ttcaagagag aatggagtga ggagatgaaa aagaaacttt ttcgtatctt tggaattgtt
     7741 ttaatcagtt tggtcactct gataatactt ttgagcttag ttggaacggt agctgaggca
     7801 acaggtctgg ttgatgatac agttggagcc ggaaatcttt attcccaata ttcacttggt
     7861 aactatcagt tggatttctt tgtggatagt tcgtgggatt ggctgccttg gaattggggt
     7921 gatggcctag ggaagagcgt aatgtatgga ctttatgcca ttactaattt tatttggaca
     7981 gttagtctct acttatcaaa tgccacgggc tacgtggttc aagaagccta taagctggat
     8041 ttcatttcag atacggctga aagtattggg aagaatatcc aaaccttagc cggcattacc
     8101 gaaaatggac tccagacctc gggcttttac tttgggtttc tattattgat gattttagct
     8161 ctaggagttt atgtggcgta tacaggatta ttaaaacgag aaactaccaa agcagtccgg
     8221 gctgtcatta attttgtgat gatttttcta ctttcgggtt cgttcattgc gtatgcgccc
     8281 acctatatca caaaaatcaa tgattttagc tcagatgtca gcgaagcggc tcttagcctt
     8341 ggaaccgaga ttgtcgtgcc gaattcagaa agccaaggaa aggacagtgt ggatttaatc
     8401 cgagatagct tgttttccat tcaagtccaa caaccgtggt tactcttgca atttgatgat
     8461 tccaatatag aagaagttgg cgaagatcgt gttaacaaaa tcctgtctgt aagtccagat
     8521 gaaaataaag gcaaggatcg ggaagaagcg gtcaaagcgg agattgaaga taatgacaat
     8581 gcgaatctca gtattaccaa gaccatgaac cgcttaggga ccgtggtctt tttggtgttg
     8641 ttcaatattg gcatatcctt ctttgtcttt ctcctaacag ggattatgtt gttctcgcaa
     8701 attctcttta ttatctttgc gatgtttttg ccgattagtt tcttattgtc catgttgccg
     8761 acttatgaga gtttgggcaa gaaggcgatt attcgcttgt tcaatacgat tatgatgcga
     8821 gcaggagtta ctttggtgat tacgactgca tttagcatct ccacgatgtt tttcaatatt
     8881 tcggcaacct atccattttt catggttgct tttctgcaaa ttgtgacctt tgccggtatc
     8941 tatttcaaat tgggcgacat tatgaatatg ttcaatctcc agagtaatga tagccaatca
     9001 atgggaagac gggtcatgcg aaaaccgcaa atgttaatga atcgaacatt gcggcaactc
     9061 aatcgaaatg tgggacggac tttggctttt ggtggtggtg cagcagttgg aaataagttg
     9121 gcaaaggaac aatcaaaatc caaatttaag ccatccggtt cttctctacg aaagaattca
     9181 cgattaccga acgatcacga gataccatct gacttgaata aggaaaagcc aattccaaat
     9241 aataagaaac aatcccgaat gaatttggcc gggagaaaag tcggcaaggt tctggatacc
     9301 caagctttgg tgaaagataa gaccaaacaa gtaaaggatg gagtacggaa tacgccaacc
     9361 aacttgaaat acaacttcca taaaggaatt gaaaaaacga aaaaagcacc ggaagagttt
     9421 aagcgaggac tggtccaaga aaaagcaaat cgaggagagt tgcgagaaaa acaacaacaa
     9481 cgtagagacg aaaaaatagc tgaaaagcgc aaagtattga acgaaatagg gaatcctcat
     9541 gggaaaagaa gggaaaatgt tccgataaaa gcaaaggtcc aatctcaaaa ggatagagca
     9601 ccaaagcgga ttgtgagagc aaattcgaat cccgaaatca aacgaaaatt cgctagccaa
     9661 gaaatcattt caaaaggaat aaaccaatcc tcaagtaaga aaaattcttt tcaacaagtg
     9721 aaacggcggt ctactctgtc caaacgaacc aatcgaaaag tacaaaaaag tttgaaccct
     9781 catcccaaac caaggtcagg tgagaaaaaa tgaacgtaaa gaaattaagt gccatttcgt
     9841 taactttcct aacaatctct tttatgggta tcttgatgtg tgtgggctta ttgtttggtg
     9901 aagacagtga aggaagtagt agttcaggtg ctcctcctgg ggggagtagt gtctcagaag
     9961 aggttttgaa acaccgtgca atggtggaaa aatatgccaa agaatcggat ataacagagt
    10021 atgttccgat tcttttagcg attattcaag tggaatctgg tggcacaatg gaagatgtga
    10081 tgcaaagttc tgagtcagcc ggtttaccac cgaattcatt aagtaccgag gcatccatca
    10141 aacaaggatg tctctatttt gcgtctttgg ttaagcgttc caaagaatta ggttgtgatc
    10201 aagatagtat cattcaggcc tataactttg gcggtggtta tttggactat gtggcaaaaa
    10261 acgggaagaa gcatagtttt gctttagctg aatctttttc aaaggaaaaa tcttgcggtc
    10321 aaaaaatcga ttaccctaat cccatcgcga ataaggaaaa tggtggatgg cgctataact
    10381 atggcaatat gttttattgc ttattggtga agcaatacct aactacaaca cagtttgacg
    10441 ataaaacagt ccaagggatt tttgacgagg cgtttaagta tgaaggaacg gcttatgtat
    10501 ttggtgggtc aagacccgaa acaggatttg attgtagtgg cttgactcaa tggtgttatg
    10561 ccaaagttgg tctgaaactt cctcgggtgg ctcaagatca gtatgatgcc atgacccata
    10621 ttgacctaaa agatgccaaa ccaggggatt tggttttctt tcattcgact tatgatgccg
    10681 gtacttatgt gacccatgtc ggtatttatg caggggagaa tcgcatgttt catgcaggag
    10741 atccagtagg ctggacgaat ctaacagaaa gctattggca gcagcatctt atcggtgctg
    10801 gacggtacaa ataagagaaa agaggaaaaa gaatgaagat aaaaattgaa cggaatcaaa
    10861 aggaaaagag cctaaaaaag aaaaaagaac gagtcgtatc cgtgggtaag catcgaaaaa
    10921 tggtgcttgc cctttggctt ttattatctt gtagtcttac ttttggcgtt tataaaaatt
    10981 tcaccgccat tgatcaacat acaactcatg aaaaagtggt tattaaagag aaagtagtga
    11041 atacttctgg tattgaaaac tttacgaagg atttttcgaa agaatatttt tcgtggaaaa
    11101 ataacaaaga agcaattgaa aagagaatga acaacctcga acagtacctt acagaagaag
    11161 gtttcgcttt aagtcaagat atggttcgag cagatattcc cactaattcc gaagttcagt
    11221 cagtaaaagt cttagatgtt gaaaagagct cggaggaatt tgtcgtttca tttttagtgg
    11281 agcaaaagat tacagaggga aaaaaggcac aatcgatttc ttctgcatac cgagtgacga
    11341 tctttgaaga tgaaaacagg aattatatag taacgagttt gccaactatg attgcaaaac
    11401 ctgatagggc aaaatacaag acaaaacaag tagaaaatga ttcgaaaatt gatgccaaaa
    11461 ctacagaaga aatcgctgag tttttggaaa cgttctttaa attatatcca tcagcttctg
    11521 aaaaagaatt ggagtattat gttgaaaatg atgcgatgcg accaatcaat attgacttaa
    11581 agttttcgaa gttagaggat ccagtttacc tacaaaacgg aaaaaaaatt ctagtgagta
    11641 caaagataaa ataccttgat aatgtatcaa aaaccactag ctactttcag tacaaattaa
    11701 tattacaaaa aaatggaaac tggaaaatca ttgatgttaa ataataatga ctcaatctaa
    11761 atttatgaga agttataagt agtttaactt atttcaggca gaagtcgccc atcctctata
    11821 ggtgggtgat gaatgccgtt cggtaactcg aaaaccgaca attaagacat agtgcctttt
    11881 tattttaatc catgtcataa tcagtctata taagaaatgg ttgatatacc atggaattag
    11941 atacaaataa tcattcatta tttcttcttt gttaccacct tattttagta gtgaaacatt
    12001 gtaaacatct cattgatgat gtaatgttag cttatgcaaa aaactatctt tgaaagaata
    12061 tcagaatcac atcacattac cttagttgag tgaaatcgtg ataaagacta ctttcatatt
    12121 atgctcaaag cacaacctaa aaccgaatta acaaaattca gcaatgccta agctcatgtc
    12181 tgataaaatg agactttcta agggtcaaaa atttcctttg aatacgatca ttagcttaga
    12241 taaaagtaaa aaccttagaa ctacggggat agcttggtta ataagagata tcgctgttaa
    12301 taaagacata agcttgcaag tatgctctat tcccaagaat ctcccacttc aagcactaag
    12361 gatcgttaaa ttcagctaag tggcaagtag ttcactagac gataattatc tccatatttc
    12421 aatctcagct tttccatttt tcatagcaaa ttccgttatt tttatagcat ctaaaagatt
    12481 cagcttttcc actgatcttt caccactttt cagctttttt attgtgctta aattgatacc
    12541 agtacctttt gatattgaat tggaagtaaa atcattaagg gtttttttta ttaaattcat
    12601 atccgcaatt ccagcgttca taagaatgaa gattctcctc tcatagacta ctttgaaaat
    12661 ggtactacag tggctgttta tatatttcag taggttactg tagtggtcat tttattataa
    12721 ttagaaaagg aacctaaatc aaaaatgcta aagaaaattt tcatagtatt aaacctatca
    12781 tgactaaagc cacggaattc ttgataaaag agtatacttg caagcctatg tctttactaa
    12841 cagcgatatc tcttattaac caatctatcc ccgttgttcc taaggttctt gatgttttct
    12901 aaggcaatgc ttgtatacat agcccttgat caaaatattg atactaacgt tgacgtttcg
    12961 atcatgatgt gtacggcaaa taggacaagt ccattctcga attgtgaatg acttcttacc
    13021 atctgtgtgt ccacattctg aaccaatttg actagacgga aatcatttat ctatcttgat
    13081 gatttttttg acagaagtat cgaaaatctt tacataatct gggtgttgca ttcttatgca
    13141 gatgagagcg ttagctccgt attcataacc agttgcctct aaaacgtagt ccatcggtgg
    13201 atacctagct tgcggttgcc agtggctttc gcagtcttct tgtaatcaaa tcgagcatct
    13261 aattgagtac tagtattttg aagataatac ttgagttttt cggttttcag aagttcactt
    13321 catcttccat catccatgga aatcccactc acccatacgc aggcctccaa aaattcttca
    13381 acaatggttt ttcagacatt tttctgaata cctccttgtt ttttgatacg ccagatagtc
    13441 aggaaaaagg caacaaaaca caaaacaaag ctgcctaaaa aggtaatctt cattccatat
    13501 aaaaagacat ccggccgatc tgcgatatag ttagttactc gttggcccat cttagcagac
    13561 atcgcttgat ataagaccgt cgtagaaagc gaaatcccga tgaccatccc caaatttcgg
    13621 gcaaaggaat tcatggagcc tgccagtccc aaattttcga tagtgacaga actcataacc
    13681 atcgtattat ttggggactg gaacaaggca ttgccggcac ccatgatggc agtagcgaca
    13741 atgtacagcc acaaaggaga gtccactgac aaaaacatat acatgacttg ggttaccgac
    13801 aataaaccca agcctactaa tacaaaaatc tccgggccaa cccggtcggt caggtatccg
    13861 cttaaaggcg ccccgacgac catcatcaag ggaaagacca tcatcaacag tccggcatag
    13921 ctaggactca acccgcgagc attttgcaga taaaaaggaa tcactacatt aacaaagaag
    13981 ttggaagaaa aaatcaacaa ggctgtaatc aagctcatgg taaaaatctt gttcttaaaa
    14041 ataccgaaag aaatcaatgg agaggctgct ttcttttcaa cttttaaaaa gctgacaaag
    14101 gcaatcactg aaattacgaa cagtacaagg gggactggat ggaaaaagcc actttcttgc
    14161 cccaaaaaga ttgttccaaa aaggctgata atcgtagccg caatggcagc aaagccccct
    14221 ccatcgattg tatggccgct catggtgata tcttttggta agaatttttc agcaatcaac
    14281 atcgttacga ttcccaccgg tacattgatc caaaaaatgt acgcccaaga aaattgggac
    14341 aaaatcaagc cgccaagacc tggtccagca atcgagccta atgaaacaag cgcaccgatt
    14401 gctcccaatg cccgaccacg ttcatgtatg ggaaagactt ccgtgatgat tccggcattt
    14461 gtagccatag tcatactagc accaatggct tgtaccaccc gtgcgaacaa ttaaatacct
    14521 agcgaatgat tgaacccaca caacagcgag cccaagacaa agatcagcgt accaatccga
    14581 aatactttga ttttcccaca gctatcgcca attttaccaa acagcaacaa acaagaacag
    14641 acaatcatca gataaacgga cactacccat tccgcttgat tcattggtat gcccatatca
    14701 tctgagatgg taggtagtgc aatattgaca atactgccat ccaatgtgga catgaaggta
    14761 aacatagata tagcaatcaa aatccaccag cgattttttt ggacttttgc atcttcttga
    14821 taactatgca taataggatt tcctttctaa tgatcgtgta gctaagaaca atataaccta
    14881 tgtctactgc ccaacaactt ctcgcgactc tagccatagg aagcttgagt aatttcgatt
    14941 tgttattctc atgtaaccat gtaagtttga gatgctttat ttgaacttac tctatagtaa
    15001 ctagtgataa ttcgctttac tttcttctag caatttctaa aagtcgactt cattgttctt
    15061 cagattaata gtgtgagcta tctcgtgaga cgtaagaaaa tttccattct actttttccc
    15121 aattttttca tatttatggt gttgcaccta tttgttttcc aatttgcttt tcaaatacat
    15181 tgctatgata ttcaattcca taggattata ctaaatgtca atagtatgaa taatatatta
    15241 tagatgttta tatatcactg ttaattatta tccacaataa ttaatgatta cctcgatatt
    15301 tgtcaatcaa aggttgaaac aatttatttt cagcatcttt tctaacttga gctgcactct
    15361 taatagaatc atacgatcct aaatagtacc tctttttttt aaagttatat acgcaatcca
    15421 tttctcttta gaacgataaa ctcccttaac accacttgta ttatttttcg gtaattttga
    15481 cgttagacac tctattactg tcccttcaac acatgtcctt gtttcttgcc tttttaaaca
    15541 tccacaactt tgagtatgtc caaaaaataa gttactataa cttatctcac acatactgcc
    15601 acactcacat tgacaaaccc attttgtttt ccatgaacag ttattgtcca aaggatactt
    15661 tgcagtaagt aatccgaatt ttttattttc aatgtgatgc ttttttgatt tcaaacatcc
    15721 acagcttttt acatcacctt ttagaagtcg ctttgccgat actaactttt ttctcccaca
    15781 cagacattga cattcccaaa caacagttcc ttcacttcgc agtttagttg gcttgattgc
    15841 aactaactta ccaaaagttt tatttgtcaa atttttatat ttatgcctat ttttataatt
    15901 tccacatcca caacttttgg ttctacctga tagtaagttt gatcgatata caatcgtttc
    15961 attcccacag tcacataggt aacgatattt tttatatcca ttatgagtaa tctcctcaac
    16021 aacagtaagg tgaccatatc tttccttcac tgcacctacc ctcccaagaa agaagtacca
    16081 tataatttca attaactttt aataaatcag aaaaaaatat tttcaatttt tcttagtctg
    16141 attttatgac taatttataa tacaagactg aacgatacgt acacgaaatc ctcaagatag
    16201 ataaattgtt ttcatctagt aaaacctgct caaaatatga gcataaagac ggcaataata
    16261 cactcgatat tcgataatgg acttgtttta tttgtcaaac tcatcgtaat cgagatatca
    16321 attccagtct caatatcctg atcaaaggtc taagaatcca accattttct tgttactttg
    16381 tcagattgat tacctttttt agtctccgaa taataaggtt ttcggatcaa ctaacatgct
    16441 ctgagaaaga ctactatctt tgcaaatttc caaatgaagg tgtgggccag tactattccc
    16501 agtacttcct acatagccaa ttatttgtcc ttgcaaaaca ttatctccag tttttactag
    16561 gtattgttgc tggtgagcat ataacgcggt tgatccatct tcgtgttgta tcaccacgta
    16621 atttccccaa gagtagtgaa actctgcttt aacaacctta ccagctttaa ctgcatgaat
    16681 cggctcaccc tgtgtagctg ccatatcaag tcctcggtga aattcatttc cacgatttcc
    16741 aaacaaactg gttattgaat aattatgaat aggcacttgg tatccagtct tactcatttg
    16801 tggaccttta acttctttat catagttggt taaatcatag gttttaatta attcatttag
    16861 cttcaaatag tattgtgtat ctgttgcata ccgtcctgta aggaatttag ttgcttctcg
    16921 atatgtttta ctattagctt ttaatgctcc tgcataaaaa tctttatttc cactaattcc
    16981 cttagttaat aatttggcat aatcttcaaa actttcctca tagttttcat acactctaaa
    17041 ttttgattgg gtcgtataaa gcgttccatt acccaaatct tcgtttgtta ccataatgac
    17101 aaagtttcca ttataagttc cttttatccc aaataaattg taattcggtg cctgagctaa
    17161 ctggctttga ccactggcag attctaagat cgcttgtgca atcataacag aagcatataa
    17221 atcatatttc tgaccaattt ttctcgcaga ctcaccaatt ttcataataa aattttctac
    17281 agattcattt ttgtcaaaat gaatttcttc attaccagat agtattggtt gtgattggaa
    17341 agattctgtt gattctattt gctgtggtgt cgaaaaattt tttgtttgtc cttccgtttt
    17401 tggcgcttcc ttttttgaag actctatatg gtttggtctt gtcactttcg aagaagttat
    17461 ttcacttgta ctacttgaag ttgttgaaga ttcggcactt gaaatcgtac tactttcact
    17521 tgacgaagtt gttgaagact cggcatttga agtcgtacta ctttcacttg acgaagttgt
    17581 tgaagactcg gcatttgaag tcgtactact ttcacttgat gaagttgttg aagactcagc
    17641 atttgaagtc gtactacttt cacttgataa agttgtcaaa agttcactac tctctgctgt
    17701 tacatcggaa ttactcattt cagtcgtctc ggttctttct tttgcaattt tgtatgttga
    17761 attttcgctt gccaacacat ggaaaggtgt tgctataaag agttgggaca ttaatataac
    17821 tgctgatgca agttttaaag attttttcat ttgatttacc tctctttttt ctctttaata
    17881 gtgttttcta ttaaaaatta tgataaatat tttcaatgaa ttgagtaata cagtatattt
    17941 cttgatttca tttagtaacg attatgtttc aatgtttaat cctgttactg cctttaaaat
    18001 aaaattatag ggttggctaa aactaggatg aaataaataa tctaacattt tcaatttgtc
    18061 taatgtaatt tgttcttcta tagcaagaga aaacattgat aatagtccag ataaatcttc
    18121 ttgactacaa agttgtacac ctactattct ctttgtattt ttttcaaagc taattcttaa
    18181 ttttacacga ctattttttc tcaaaaaaac aggtctaatg aaatcttcta tttctatata
    18241 atctatagac tcacttaata atcgtgctgt ttttaaattc aaacctgctg cgtaaaaatt
    18301 gtaattaaat atagaaaagc catttgtaaa ttgggaacca gaaggtgtaa aatcttgatt
    18361 gtcaatatgt tgagttgcaa tataagctgt tcttagagca ttagaaatag aaaaatcaac
    18421 actacttcta ttaatggacg taaaaaaagt tgtagcacaa tccccaatag catatatatc
    18481 ttttatattt gtttgctggt attcattagt tagatatgct ccactaacat ctctcaagag
    18541 ttcctttttg ccaattggac tattagatag aaatcctata gcttgtacga ccatatccat
    18601 agagtattgg gtaccacttg tagtgactat tttttcaatc ttttttcttc ctaaatattt
    18661 tttaggactt tctgatagac aaagatgtat tccatttttt gatagtattt cttcaacttt
    18721 atctgaaaaa ctacggtcgt aataagtcga caacactcta tctgcaacat cgaaaagata
    18781 tacttctttc cctctttttc ttatggcttc agcaatttca actccaatat atcctgctcc
    18841 aataattcct acttttttaa tagtattatc atctaaagct ttaaaaatct ctttagcatt
    18901 tggaaaattc tttatcgaaa aaatattagc taaattattc cccggtacat ctaacataat
    18961 ttgctttgaa cctgtagcta gtataagttt gtcatattct tgggaaaatc ttgtgccatc
    19021 tttttttaca caaataatct ttttattttg aatatcaatt ttgtcaactg ctgtctccaa
    19081 aaacaacttt tttatcttag aatttagttc tcttctattt tgataaaaaa gatcttctaa
    19141 attgctaact tctcttttta tgaacaacga tgtcccacat tctaagtaac taatttctga
    19201 ttttttatct atcagaataa cttcataatt tgaatcacat aagtttagaa atcgagctgc
    19261 agctagcccc gaatggtttg atccaataat tactattttt ttcacttaat cacattcttt
    19321 tcccttctat gaaaagtatc ttcattttta actaacaacc tatctcccaa aataaaaaac
    19381 aaaaagagga agaaaaagat tcttcctctt ttcagagaag atttaagaaa ttgattttct
    19441 attcattctc tttttttcga tttttatacc ctaataaccc taaagttcct aacaggatta
    19501 aaccaccact aatagtaaag atattactat caatctctcc cgtcttagga taagcttttg
    19561 aggactgctt ttgaggactg cttttgcctc tatttttgtt ttgcttgcta ccttgattgt
    19621 cagtcttatt atctttacta acggcttttt cactgtcttt ttcgtttgaa gaaacaacta
    19681 cattagtagg ttcactagta ttaccagatt catcagttgc agttactatc acttttgttc
    19741 ctgcctctaa tttaggaact ttaactgtaa aattaccatt tttatcagct gtcccatggt
    19801 attgactccc gtttggtaat gtaactgtca cctctgcatt tggttcagtt ttaccagtaa
    19861 caatttggtc accctctgta ataggatcaa cttgaggttt attcggtgct tttttatctt
    19921 ctacagaaat agtaacctct acttcttctt tagatccatc tggatatgtt actactacaa
    19981 tccctttttt gtttccagct gtactaacat ctactttctc tttccaagta taagtagttc
    20041 cttttggtag atcttctttg ttcttaattc cctcagatgc gtctggctct ttatttaagt
    20101 ctgtagtcac tttttgtcct tcaggattgt atttatcggc atc
//
LOCUS       DAZUJR010000055        19593 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.055, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000055 DAZUJR010000000
VERSION     DAZUJR010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19593
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.055"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            135..794
                     /locus_tag="ACG804_001875"
     CDS             135..794
                     /locus_tag="ACG804_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFS4832801.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            879..1784
                     /locus_tag="ACG804_001876"
     CDS             879..1784
                     /locus_tag="ACG804_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFS4832802.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(1786..2418)
                     /locus_tag="ACG804_001877"
     CDS             complement(1786..2418)
                     /locus_tag="ACG804_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFS4832803.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     misc_feature    2569..2694
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            2738..3262
                     /gene="infC"
                     /locus_tag="ACG804_001878"
     CDS             2738..3262
                     /gene="infC"
                     /locus_tag="ACG804_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HFS4832804.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            3334..3534
                     /gene="rpmI"
                     /locus_tag="ACG804_001879"
     CDS             3334..3534
                     /gene="rpmI"
                     /locus_tag="ACG804_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HFS4832805.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            3587..3946
                     /gene="rplT"
                     /locus_tag="ACG804_001880"
     CDS             3587..3946
                     /gene="rplT"
                     /locus_tag="ACG804_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HFS4832806.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            4198..5535
                     /locus_tag="ACG804_001881"
     CDS             4198..5535
                     /locus_tag="ACG804_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HFS4832807.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            5583..7712
                     /locus_tag="ACG804_001882"
     CDS             5583..7712
                     /locus_tag="ACG804_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HFS4832808.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            7687..8376
                     /locus_tag="ACG804_001883"
     CDS             7687..8376
                     /locus_tag="ACG804_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832809.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(8784..9397)
                     /locus_tag="ACG804_001884"
                     /pseudo
     CDS             complement(8784..9397)
                     /locus_tag="ACG804_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            complement(9533..9727)
                     /locus_tag="ACG804_001885"
     CDS             complement(9533..9727)
                     /locus_tag="ACG804_001885"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832810.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(9777..10217)
                     /locus_tag="ACG804_001886"
     CDS             complement(9777..10217)
                     /locus_tag="ACG804_001886"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HFS4832811.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            complement(10221..11066)
                     /locus_tag="ACG804_001887"
     CDS             complement(10221..11066)
                     /locus_tag="ACG804_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HFS4832812.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            11215..12633
                     /gene="pepV"
                     /locus_tag="ACG804_001888"
     CDS             11215..12633
                     /gene="pepV"
                     /locus_tag="ACG804_001888"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HFS4832813.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(12690..13637)
                     /locus_tag="ACG804_001889"
     CDS             complement(12690..13637)
                     /locus_tag="ACG804_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFS4832814.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(13860..14210)
                     /locus_tag="ACG804_001890"
     CDS             complement(13860..14210)
                     /locus_tag="ACG804_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFS4832815.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            14410..15489
                     /gene="pepA"
                     /locus_tag="ACG804_001891"
     CDS             14410..15489
                     /gene="pepA"
                     /locus_tag="ACG804_001891"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HFS4832816.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            15633..15953
                     /locus_tag="ACG804_001892"
     CDS             15633..15953
                     /locus_tag="ACG804_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HFS4832817.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            15975..16439
                     /locus_tag="ACG804_001893"
     CDS             15975..16439
                     /locus_tag="ACG804_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFS4832818.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            16644..17249
                     /gene="ytpR"
                     /locus_tag="ACG804_001894"
     CDS             16644..17249
                     /gene="ytpR"
                     /locus_tag="ACG804_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HFS4832819.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(17288..18577)
                     /locus_tag="ACG804_001895"
     CDS             complement(17288..18577)
                     /locus_tag="ACG804_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HFS4832820.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            19005..19484
                     /gene="rlmH"
                     /locus_tag="ACG804_001896"
     CDS             19005..19484
                     /gene="rlmH"
                     /locus_tag="ACG804_001896"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HFS4832821.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
BASE COUNT         6236 a         3603 c         4017 g         5737 t
ORIGIN      
        1 tttcttaaga attttttgac tttttttctt ctttgactag aaaaaaatac aattgacact
       61 actagatatt gggggtatat ttaaaaaggt tggagttaaa cacaatattt agtgatgaag
      121 tgagctggag gtaaatgagc gtgatcgttt tagcaggtac aattggtgcc ggaaaatcaa
      181 gtttaacaga aatgatggct gaacactttg atagtcaggc attttatgaa tcgattgatg
      241 ataatgaagt cttgccctta ttttatgcaa accctgaaca gtatgctttt ttgctgcaaa
      301 tttatttttt gaataaacgt tttgcaagca tcaaacaagc aatgaaagat gacaataatg
      361 tattggaccg ttcgatttat gaagattcac tgcttttcca tctaaatgca gatctaggaa
      421 gagcaacaga aacagaagtt cgtgtgtatg atgaactgct ggaaaacatg atggaagaac
      481 ttccctatgc tgcccataaa aaacatccgg atttattagt tcatattcgt gtatcttttg
      541 atacgatgtt ggagcgtatc gaaaaacgtg gtcgttcgta tgaacaattg tcctttgatc
      601 caagtctata cgattattac aaagaattga acagacgtta cgatcaatgg tatgaagaat
      661 acaaagaaag tccaaaaatc caaatcgatg gagaccgcta taattttgtg gaagatcctc
      721 aagcaaaaga agaagtcttg aaaatgatcg aagaaaaatt agcagagatt cgccaaacca
      781 aagtagccat ttgatttaca gttgctcaaa taaagggtaa acctttattt gagcgacttt
      841 tttctttata ctggaaacaa atgtcaggag gatagagtat gcgggaaaaa cactatttta
      901 atcaagaccg taatttttgg atcaatgtac agcaaaacga tgtgctagct gttaaaaact
      961 taaaagaaga atatggcatt agtgacgaga tgctgactta ttctctagat aaaaatgaac
     1021 gggcgcgcgt agagtacgat tcttttgatg aagcgttact gcttgtatca aatgttccgc
     1081 accagcaaaa agtcgataat cattatgaaa ctagtcctat cgcttttatt ttaaaagaag
     1141 acggtttgtt tacatttacc acgccgaata ccgagtacgt gattcgacta attcgatcgc
     1201 ttttggaacg aatgccagac atgagtgtat acagtttatt gtttcgtaca ttgtttttga
     1261 tttctgattc cttttttcct ttaatcgagg aagtgaatag tgaacgtcag cggcttaatc
     1321 tgaaattaag agaaaaaaca acgaacaaga atctgctgca actttcagat ttagagatcg
     1381 gtttggttta cttagttaca ggaacaaaac aaaatgtagt acttttagaa caaatcaagg
     1441 cattggctat ttatcgcaag ttgtcagaaa aggaaaaaga agagttggac gatgcgctga
     1501 tcgaagcacg acaagcagtt gaaatgacga acttagcttc gcagatttta gaccagctct
     1561 ctggcactta taataatttg ctgaataaca acttgaatga cacgatgaaa tttttgacgg
     1621 tctggtcgct gatcttgacc gttccaacta ttgtgacagg attcttcgga atgaatctcc
     1681 agttaccctt tacccattcc gttttcggat ggggaatcgc cttgatcatc agtttggtct
     1741 tatctatttg gatgcttatt gcactgtggc ggcggattcg ttgatctagt ctttgatctg
     1801 caaaccaagg gcttgggcga tcacaagtgc ttgctcttgg ttgacgatta gtcccgccaa
     1861 agaatcttga gataaagcga ttgctgtgaa gaaattagtc gtaaagtcta atcccttcag
     1921 agaagttcga aaccagttcg aaccggtcaa ctgattgtca gacaaaaaaa ggtttttcca
     1981 agtgacctca taaaattcgc tgtcttctaa ttgacaatga tcgaaggaga cagctttcaa
     2041 gtttgtacta ctaaaggaag ccatcgaagc aatacaatca gtgaaagtac agtctcgaag
     2101 ataactttcg gcaaaattcg tacctgttaa tttacattga tgaaacacga cttggtggaa
     2161 actgccacca atccactcca gattggaaaa atcacatttt tcaaaaatga cattactgca
     2221 ttcaaaatga cgtaaaactg ttttttgcat cgtaagtttt tggatatgac tctctcttaa
     2281 taccatattt ttggcatcga gatagctttg gtcacccccg ttgatcagaa gaccagagaa
     2341 gatctcctca tcttctaaat aaaactctcc ctttgtaaga agaggaagag aaggtggaat
     2401 aggttcgatt tttttcatgt gggttcacct cgtttttctt tagtatagca aagaagcggg
     2461 aatcactgct agaaagtctg ctaatctaat cattttcaga aaaggaagac aaactgtatg
     2521 aaaaacattg acaaaaagat tagtttttgc tatactatga tggttgagaa ataaaagcag
     2581 aagcacccgc ttctcgcctt agttgataat gtcactgggc tagatagttt tcactggttc
     2641 tattaggtga agtacgcgcg ggttctgtaa gagaactcgt ttttttattg ccgtttattc
     2701 ggtaagcttt tctttctctc ataatatttg gaggtgaatg accatagcaa aggatatgat
     2761 ggttaacgac ggcattcgtg cacgagagtt acgattgatc ggttcagatg gtgagcaatt
     2821 aggagttaag acaaaagcag aagcattgaa tattgcagaa caagcaaact tggatcttgt
     2881 gttagttgcc cctggtgcga aaccaccagt tgcgcgaatc atggactacg gtaaataccg
     2941 tttcgaacaa caaaagaaag accgcgaagc gcgtaaaaaa caaaaagtga tcaatgtaaa
     3001 agaagttcgc ttaagtccta cgatcgactt gaatgacttc aatacaaaac ttcgtaatgc
     3061 acgtaagttc ttggaaaagg gcgataaagt gaaagcttct atccgtttca aaggccgtgc
     3121 cattacccat aaagaaattg gtcaaaaagt cttgaatcgc ttagctgaag aaactgcgga
     3181 tattgcaaca gtggaacaaa aagcgaaaat ggacggacgc agcatgttct tgacgctggc
     3241 accgaaaaac gacagtaagt aatttgaatg actaactggc tgttggacag ccgatagtcg
     3301 gataacgaaa gattttgagg aggaaatata gtcatgccaa aacaaaaaac acaccgcgga
     3361 tcagcaaaac gtttcaaacg tactggtaaa ggcggattga aacgcttccg cgcgtttaca
     3421 agtcaccgtt tccacggcaa aacaaaaaaa caacgccgtc aattgcgtaa agcaagcatg
     3481 gtttctagtg gcgacttcaa acgtattcgc caacaactag caaaaatgaa ataagaagta
     3541 caaataacag aatctgaaga tttattttta ttaggaggaa ttatacatgg cacgtgttaa
     3601 aggtggaaca gtaactcgta aacgtcgtaa aagagtgcta aaattagcaa aaggttacta
     3661 cggttcaaaa cacactttat ttaaaacagc aaaagaacaa gtaatgaatt catacaacta
     3721 cgcatatcgc gatcgtcgtc aaaagaaacg cgacttccgt aaattgtgga ttgctcgtat
     3781 caacgcagca gctcgtatga atggcttgag ctactcaaaa ttaatgcacg gtttgaaagt
     3841 tgctgaaatc gacatcaacc gtaaaatgtt agctgacttg gctgttaacg atgcagcagc
     3901 atttactgca ttggctgacc aagcaaaaga agctttggct aaataagcta aacaattata
     3961 aagaggaaag aagataacga aaagttatgt tctttcctct ttttttattt acaatcctcc
     4021 atcaaatgaa acaggacaat aacgtataag tctaaaatag cataattaag gttttttaat
     4081 tgaaaactga acatttatgg tcacccttta atgaaagcgc taactacata agttagaatg
     4141 agtttgactg atatattagt ttgcttatca gaaaaacaaa atggacggag gaataacatg
     4201 agtgatatta ttattggtat tttgttagtt atctcattct ttttcatggt ctggtactgt
     4261 gtaaaaggct acaacttgat ggtcggcttt gccatcatgg ctactgtatg gatgggatta
     4321 gcgctagtcg gaaacacgtt ttcaccaaac ccggcgatgg aagggcaagg agtaattgat
     4381 gtgttgacgc atatctatac gacggggcca gctgagtacg ccaaatcgat cttggtaaat
     4441 gtcttctttg gtgccttttt cgggcgtgtt ctagtagata gcggaatcgc agctaccctg
     4501 attcgaaagg tagttgaact tggaggggac aagccaagaa tcacgatgag cttactatgt
     4561 attgtaaccg ctgttatatt catgtcgatg acaggaatcg gaccagtgat ttctattgca
     4621 gttattgtgt tgccaatctt gatgtcatta ggtatttcag taccggttgc actgttctca
     4681 tttatgggct cgattatggc tggaatcttt gctaatatcg tcaatttcaa acaatatcaa
     4741 acgatttatg ctggtttcaa tccagcggct gaaagctata cttataatga ctatttccaa
     4801 attggtatga ttgggatgat tgtaagctta gttgtggtac taacggtcgc taatatatca
     4861 atgaacaaaa agaaacgcta tgcaatggca gcaaacgtac cagctgaagg tggcgacgca
     4921 ccaatgatct catggttagc cgtattatta ccagttttag gggtcgttct tttagatctt
     4981 ccaatcatct taggttttat tctagcaggt atctgggcat tgctgtttac tggaaaattg
     5041 cgcggaggtt ataaagaaat ctgtcgtcag tttgcgaaat tatttacaga tggcgcagta
     5101 gatgttgcac caatggttgg tttcttgatg accttagcga tgttcaataa ttcagctgcg
     5161 tatgcttctc cttatttttc agctattttt ggagattgga taccgcaatc accattagtc
     5221 ttggcaatcg tatttgctat attgacacca ctaggatttt tccgcggtcc aatgaatcta
     5281 gtcggttcag gctcagctat tttagctgtc gtattagctg ttaatccaac gatgtcgcca
     5341 gcctttttgt tcccgttatt tgcaatcaca acgattgctc ctcagcattt agatattaca
     5401 caatcttggg ttgcttgggg attaggttat acaaaagtaa cttctcgaga atatatgaag
     5461 aaatccatcc caactggttg gatcatcgga gcgatcttat gcctgatcac gttcttattg
     5521 tacgggaacg cctagtaaac aaaacgtcga taaaaacgat tagatgaatg gaggaaaaga
     5581 aaatgaaacg ttttgtgcga atgggaattg atgttggcgg tacacatacg aaagcagtcg
     5641 caatcgataa tgcgacgcac gaaatcatcg gaaaatcttc agtgaaaaca acccacgatg
     5701 atgtccgtgg agtagccgca ggtgtcgttc agtcttttca aaattgtttg cgggaaaata
     5761 atatcagtcc agaagatgtt gtgtttgttg cacattctac cacacaagcg actaatgcac
     5821 tgattgaagg agacgtagca aaagtcggcg taatcgggat ggcaaaaggt ggattagaag
     5881 gttttttagc aaaacgacaa actagattga acgatatcga tttagggaat aagaaaaaaa
     5941 tagagattgt caatgcattc ttacctgtca aacacttaaa tgtagaccgt gtttcagaaa
     6001 cgatttcttc tttagaaaga gaaagagcgg aggtcttggt ttcttctatg gcatttggag
     6061 tagataatgg ggaaccagaa cgagttgttt atgaagcagc atcggtaaaa tcgatcccta
     6121 caacgatggc ttctgacatc acaaaattat atggattgac aagaagaact cggacagcag
     6181 caatcaatgc atctatttta ccaaaaatgc tagatacggc aacctctaca gaagattccg
     6241 tacgagaagc aggggtcaat gtttctttga tgattatgcg cggagacggc ggagtaatgg
     6301 aaatcaatga aatgaaaaaa cgacctgttt taaccatgct ttccggtcca gcagcatcag
     6361 tcatgggctc tttgatgtac ttgagagcgt ctaatggtgt ttattttgaa gtaggcggaa
     6421 caacaaccaa tatcggggtc attaaaaatg gacgtccagc aatcgattat tcaattgtag
     6481 gtggccaccc aacatatatc tcttcattag atgttcgggt tctaggtgtg gcaggcggtt
     6541 cgatggtacg ggctaatcag tcaggaatca tcgatgtcgg tccacgttct gcacatattg
     6601 ccggtctaga ttatgcagta tttacggaga cagaaaaaat caaaggtcct aaggttgaat
     6661 ttttctctcc taaagaagga gaccctgctg attacgtcaa ggtagtgatg gaagacggag
     6721 aagaagtgac tattacaaat acatgtgcag ccaatgtcct tggattagtg caagaagaac
     6781 atttttctta tggaaatgtc ccatctgcac gaaaagccat ccaagcatta gctgattatt
     6841 gtcatacgac ggttgaagac atcgcagaac agatcatgga aaaatcctat gctaagattg
     6901 aaccggtgat tttagaattg gcagacaagt atcacttgga gaaagatcag atttctcttg
     6961 taggtgtagg gggcggcgct gcctcattga ttacttactt tagtaataaa atgggtgtga
     7021 aatattcgat tcctgaaaac gccgaagtga tttcttctat tggtgtagca cttgcaatgg
     7081 tccgagatgt tgtagaacgt atcatccctt cgccaagtaa agaagatata cgatcgttga
     7141 aaaatgaagc gatgaataaa gcgattgaat caggcgctac accagaatcg atcgaagtcc
     7201 acgtagaaat cgatccacag acttcaaaag taacggctat cgctactggt tctacggaag
     7261 tgaaagcaac cgatctaacc aaggagatca caacagaaga agcactagag cttgctgcag
     7321 aggatatgcg attaaataaa aatgaagttt gcttattgga aaatacacct ttcttttatg
     7381 tatgcggcga acagaatcgt tcaaaaaatg ctggaagtct tcggatcatc gatcaaaaag
     7441 gatttatcaa ggtccaacgt ggacatgctt catgtatgaa aacaactgca gccaattata
     7501 tgacagctgt cgaacaactt tgggaagata tggcagttta tcaaactgaa ttgattgccc
     7561 gaccagaatt ttatctctgc ttaggagcaa gagtctctga ttttacagcg acggatctgg
     7621 aacaactaca gcttttgatg gatctggaag tatctactat ggaaccggag gaagaagtga
     7681 tcgtcgttgc cggaaatatc aaacaaacat aagttagaag agttactaaa cgaattacaa
     7741 cagatccccg aagaaatttg gggattctac cagtttcggc gagatttatt ttggaaaaag
     7801 attcctttgt ccaagcagaa aattcttata caacaatcaa tcgattgtgg tatcgaaacg
     7861 gcatgtagca tcaaaaaaaa gtaccctttt gccgatgtag gagaaatttg tgaacaaatg
     7921 gctgttccaa tcgtttcctg tgaatcagag caaataaacg aacgaatcac ttttgcaact
     7981 tatgcagaag atgaagggat tcgattgatg acggagccgt tagaaaaatt aaaatgttca
     8041 ggactagctt cgatctctaa agaaacagcg caagctttga ttattggaca tgaactattt
     8101 caccacatcg aagcttctgt taagggaatt tatacgcaaa gcgaaaaaat tgtgctgtgg
     8161 cggttgcctt tttatacaca tcaatcaaac attcgtgcat tgagcgagat agcagcgatg
     8221 agtttttcaa aagagatgaa tcaaagcgat ttttcgcctt atgtattaga ggcagtctta
     8281 ctttggccat ataatgaaat tcgtagccaa gggatcttag aagaaataaa aaaaatagaa
     8341 aaaagatgta cggagtatga tttagattac aaataaagag actgtgacaa aagtcgtgtc
     8401 acagtccttt ttttccgaat aaacgatgtt ctcctgtcaa ctcctcggtc acaagtcaaa
     8461 atattcaaca aacatgagaa gctgtttttt gaaattgttc cttgtgactc ggagatgaac
     8521 ggcaggctca cgacctcttg gaaaacggtg ttcaaaagct tgcatctgcg gtaataagtc
     8581 cagccaagtt aaaaacataa gaagctattt ttacttggct gttcttatta cttgatgcag
     8641 ggcagctttt tcacaacctc tcaataaacg gtgtgcaatc agctgaccct cggtattagc
     8701 tcaaaaaaaa cggcaaaata tgaggaacta ttttgccgtt tctttctcta atactcaggt
     8761 caaaacgctg attccaaaac ctcttatttg atgggtctgt cctgaatatc ttcaaaataa
     8821 tcggggtaat tatgaatcac gtattcttgc tcctcgataa tcatatgtaa atgcatcgtg
     8881 caaagaaatc cgacttcatc aaagttatga tcaatcattg attgaagcat tgtctgatgt
     8941 tcatctaata ctcgacccca gtctaattct gaaatcgtca aacgtaacca tctgaaacgg
     9001 ttcaagtgcg tactataact ttctagccaa tcccaaattt ctcgttttcc agcaatttca
     9061 taacaagttc ggtgaaaatc agtatccaaa tcaaaaaaag cttttttatt ttgagcgatt
     9121 actgcctgat cggtttttcc aacttttccc gcgtataacg ggctaatgaa gcagatcgga
     9181 tatcgatttt tgaaacataa gtgccggact gtggaatggt ttttacaagc tcttgattgc
     9241 gcagttggat cagtgcttct cgaatcggtg tacgcccgat agctagttgt tcttctaaca
     9301 ctttatcgga gattttactt ccaggtgcta actcggaata aatgatttgt ttacgtatag
     9361 attcataagc ttgctgttgc aaattattga taaccattta accttccttt ctatgcagat
     9421 ataatctatt ataacataaa tcgcttacaa atcgtgtggg cataaaaaca cagtctgcaa
     9481 aaaaagccct gataggcatg cctattagag cctcgaaaag aaaaatattg aatcaatctg
     9541 gtcgtacctc ttgtatcggt ttgacacgac cgccgattct tttagcaaaa gcttcggatt
     9601 cttttttgtc tttgaaaatg agcagattgt ctaagttttt ttcccgagtg cgacagccag
     9661 ttttatcgat gtaaccgtgc attactttaa cgacatacat ggggatcacc tgcttttttc
     9721 ttttcattat acgaactact cgacacaata caagaaaaat gcttagacgg tctttattaa
     9781 gaatttacat catccaaaga agcgtacgct tggaataact gatctaactc cggattgact
     9841 ttgctcagct tcactaatcg ttgcgaatca gaaagtaaaa aacagtgttt actactgcca
     9901 gtagttttta attttttgtc ttcagttccc acaatttcgt agctaaaatc caaccgtgtc
     9961 cccgtatact tttggatagt tggatggatg ctcacttttt ctccgtaatg gatcatttct
    10021 ttatagctgc aatttacttc cagaacgggg atgatgatcc cagattcttc gattttttta
    10081 tagggaaacc ctagatgtac caataaggct acccgagcct cttcaaacca gcggatataa
    10141 ttgctgtgat gaataatccc catttgatct gtttcataat aaaaaggttc tcgcacataa
    10201 cctgtaaatt tctccatgac tcatgcctcg ttttccattg attttttaca aaaataattc
    10261 atccatttcg gaagtgcttc gctgatttgt gtcggcaaaa caatatattg ttcttttgcc
    10321 agctggtctc caatgaaact atgaagataa atagctgctg caatcgtttg gtcattttga
    10381 ggaaactggg ctaaaaatcc tgtgatcatc ccagctaaag tgtcacccat gccgcccgtt
    10441 gccatagcag cagaacctaa aggattggtg tagaagtgct ggtgaccata aatttttgtc
    10501 tcatgacttt tcaaaacgag cacagcaccg atttcctgtt gcttcttttt gttttcttta
    10561 tcccgttgtt cttgtatcgg tagagaactc aaccgttgcc actccatttg atgaggtgta
    10621 agtacagttt gttcgggata gggtagcaaa agatgattag cagcaagtaa acttaaagca
    10681 gagccatcaa tcaccagcca ttgttctttt gattggtttt ctagtacttg tttgaaacgt
    10741 tccaaactct tagaagaagt acccaatccg ggaccaatca agagtacatc tgcttgcttt
    10801 attacggaaa gaaactggtc agtatccgtc caaactacaa tcattgcttc tggcagatga
    10861 ctgtgaagag cactccgatt tttttcatca gttactacag tcgtgagacc cgctccgctg
    10921 tgtacggcag ctaaagcact cataatgatt gctccgccat attgttcatt gccgccaatc
    10981 aaaacgatac gtccaaatgt tcctttatgt gaaatttttg gacgaggtgt gatgactctt
    11041 ttcactagtt gttcgtttat cagcatctaa aaacctcctt ttactcatta tagcgtatat
    11101 tttttttaga gaaaaacaga taagaaaagg aattgtcaga ttttttgaac tatttttttc
    11161 tgtaatttgt ggtatcatga acacgaagac ttaaataagt ggaggattaa ctttatgaca
    11221 attgattggc aaaaagaagt agaagcacgt aaagaagact tgcttgaaga cttgaaaaat
    11281 cttttacgtg tcaacagcga gcgcgatgac tcaaaagtaa caccagatgc accatttgga
    11341 cctggacctc gcgacgcatt gaaacatatg ttagcttatg gcgaacgtga tggatttaaa
    11401 gtaaaaaatg tcgataacta tgcagggcat attgatcttg gcgaaggaga cgaaacgcta
    11461 gggatatttg gacacatgga tgtcgttcct gcaggagatg gctgggacac agatccttat
    11521 gaaccagtaa tcaaggatgg aaagatcttt gcacgcggat caagcgatga caaaggtcca
    11581 agtatggcag cttactatgc gatgaagatc attaaagaac ttgacttgaa actatcaaaa
    11641 aaagttcgct tcgtagtcgg cagcgatgaa gaaagcggct ggggcgatat ggcttattat
    11701 ttcgaacatg aagaagaacc agattttggt ttctcaccag atgctgaatt cccaatcatc
    11761 aatggtgaaa aaggaaatgt ttctttagct ttacgcttca aaggcgacaa tgcaggagat
    11821 tatgtcttga aatcttttgt ttccggactt cgcgaaaata tggtgccagg aacagcaact
    11881 gcagcacttc aagtaccaag tgcagatgca gctatcgcga tggaagaagc attttaccaa
    11941 ttcatcgaag caaatccagt aagcggaacg attgaagcgg acaatacgta tgtaaaaatc
    12001 gaattagttg gtaaaggcgc acatggtgca agcccacaat ctggtatcaa tgcaggttct
    12061 ttcttggcat tgttcttaga taactatgaa ttcctaggat ctgctaaaca atttatccat
    12121 gtagcagctg cttatgtcca tgaagatttt tatggagaaa aactaggagt cgcttatgaa
    12181 gatgaaaaaa tgggcaaatt gacaatgaat gctggactat ttgcttttga agaaaatggt
    12241 acagaggaag cgaacttcat caatatgaat ttccgttttc caaaaggtgt aacagtagac
    12301 ggattgcaaa gtgacatcga acaaacagtg gggcaagaag gcgcaacagt tactcgaggt
    12361 gctcgcgtaa tggaaccaca ttacgtacca atggatgatc cattggtggc tacattattg
    12421 caagtctatg aagaccacac tggagaaaaa ggctacgaac aaatcatcgg tggcggaact
    12481 tacggacgtt tgttgaaacg tggcgttgct tatggagcga tgttcccagg atatactgat
    12541 acaatgcatc aagcaaacga atttatgagt cttgatgact tgttcagagc aacagcaatc
    12601 tatgcagatg ccatctatcg tttggcgaaa taattaatta aaaagaggat caagaattgc
    12661 aaattatttt tgcagtcttg atcctttttt tactttctac tgtggtattc atgataaaca
    12721 tgatatagat tcaattcata ttctttctta gcgttcgtga cgactgtatc caaaatcaac
    12781 cctgttacta atgaaagaag tgctaaagtc atcaatccag tacttaaaat cgcagaaggg
    12841 atgcgtgtaa taaagcttgt cagcatatat tcgcgaatca caggaatccc cgtgaccaat
    12901 ccaaataaaa agaagaagat ggtccaaatc ccaaagaaaa gcaaaggctt ataatcttta
    12961 aacattttaa taatcatcat gatcactttg aatccgtcag agaatgtatt caattttgat
    13021 tcgctgcctt caggacgatc acgataatcg attgggattt caacgaactt gaatttttta
    13081 tctaaagcat ggatcgtcaa ttccgtttcg atttgaaaac cagaactcat aataggaaaa
    13141 cttttgacaa agatacgatt gaatcctcga tagccggtca tgacatcaag aatttttgtt
    13201 ttatacattc tagtaattgt atttctaaca aggttatttc caaaatcgtg gaaaggtctc
    13261 ttattctcat caaagtaggt tccatttgat aggcgatcac caatgaccat atctgcttca
    13321 ccagaacgta atttctcgag caaaccatgt acagcttctg caggataagt atcatcgcca
    13381 tctaccatta aataatagtc ggcatcgata tcaaagaaca tttggcggat cacatttcct
    13441 tttccttgac gaggttcttt ttttacgatt gctccacctt gaacggccaa ttcgtatgtt
    13501 cgatcggtcg aattattatc atagacataa atatctgctt ctggtaattc tcgtttaaag
    13561 tctgcaatga ctgttgaaat tgttgcttcc tcattgtaac aaggaatcag aacagcaatt
    13621 ttttcttgtt gttccatttt tcactctcct taactataga aaacaaaagc taaattaaaa
    13681 atacctcata atcaaaggaa atgctagttt ttcccgctaa atatcattta tttaaaaaga
    13741 aaatactgga atatatgttt ggaaagctct atctaaaaaa ccacccacta caaaagaagg
    13801 acatgatacc tctcttttga atagtgggtg cgtattcgtt ctctcacttt tttgacgtat
    13861 taatctgttg cacctttttt tcttgaaatt tctaatacgg ttcctgtatg agcatctgct
    13921 aaaaattcat aataaacagt ttcgccatct tctattcgag aaagacctcc ccgataagca
    13981 ctcgaccgaa cggcgaattt cctaataggt tccttttcaa aagagatcca agaaccttcg
    14041 attgcacctt cttttagaaa agatgacttg atattttcaa gtacttggtc tgctgacaat
    14101 acttttttgc gatgatacca aatcgttgaa gctaccccgc tcaataatcc tagaccgatt
    14161 ccaactgcta acccgccttt aaaatagctt agttcgcttt cttcatacat gtggacatac
    14221 ctccttcttc tcacttgtta ctccttgtgc ttattttacc acactctcat attttctttg
    14281 aaataaataa ccgctaccag aaaaaataag ctataataaa tacgatcggt ctgcagaaaa
    14341 aatcatattt tatccgcaga tcaatataag tctgagagga gtttagtctg aaatttagac
    14401 gaatagcata tggaagaaaa aacatttcaa cgaatcaaag agttaacaga attacaagga
    14461 acaagcggtt ttgaacaaga tgttcgcgct tatatggaaa gtcatatgga accgctggta
    14521 gatgagttac agttagatgg tttgggcggc atttttggtc tgcgccatca tgaagaagcg
    14581 gatgcacccc gtgtaatggt cgcagcacat atggatgaag tcggattcat gctgacacaa
    14641 atccaagaaa acgggctttt taaagtcgta cctctaggcg gctggaatcc ttacgttgtt
    14701 tctgctcagc gttttacact taaaacctct actggtaaga attatccatg tatttcttct
    14761 tccgttcccc cacatttatt gcgaggaaca agcggacaaa aatcagtaga agtaaccgat
    14821 attttgttcg atgctgggtt tgaatcaaga gaagaggcaa tgagttacgg tgtccttcca
    14881 ggagacacaa tcgttcctta cgctgaaacg atcaaaacag ccaacggaaa gaatattatc
    14941 agtaaatcat gggacaaccg ctatggctgt acaatggtat tagaagcttt agaagcgttg
    15001 caaaatgaaa cattaggtca tacattgatt gcaggcgcga atgtccagga agaagtaggc
    15061 ttgcgtggtt ctaaagcttc tgtcaataaa ttcaagccag atctgttctt tgcagtagac
    15121 tgctctgcag cagatgatac agtgacgaaa aatggcacat tcggacattt aggagaaggt
    15181 acattgatgc gtatccaaga tccaggtttg atcatgcttc ctcgtttgcg cgagtacttg
    15241 ctggatatcg ctgaaacaaa caatatccct tatcaatact ttgtttcaaa aggcggtaca
    15301 gatgcaggtg ctgctcatac acaaaacgaa ggaatcccaa gtacagtgat tggcgtagtg
    15361 ggacgttata tccatacgca tcaaacgatg ttcagtattc gcgattttga agctgcacga
    15421 gaaatgttga ttcaaacact gaaaggtttg gataaatcaa cagtgaatac gatcgtatac
    15481 ggaaaataat gcgatagtga aactataaaa tctggcaaaa gattgctttt tgccagattt
    15541 tttttataaa aagaggatca atgtttgtta gttcgaaaga aaggtgtata atttaattga
    15601 aaaatacata aacagaaagt agaggacaaa gaatgattat cccaaatagt ttagaagaat
    15661 tagcaggcta cgtagaaact ggaaagagtg tatttttctt tactgccggc tggtgcggag
    15721 actgccgttt tatcaaaccg caaatgcctg aaattgaaaa tgacttttct gattggcaat
    15781 ttattgaagt agaccgtgac aagtacatag atgtagccgc tgaatggaac atttttggta
    15841 tcccaagttt tgtcgtgatc caagacggaa aagaattagg tcgtctagtg aataaagatc
    15901 gtaaaacaaa acaggaaatc gaatcgttcc tagaaagtgt aacaaaaggc tgacatctgt
    15961 taggaggggt caagatgaat caagaatata agaatatttt agtaggtatc gacggtagtg
    16021 aacaagcact tgctgctttc aaaaaagcgg tagaagtggc tcgccgtaat aatgggaaag
    16081 tatatgtagc aaacgtaatc gatcagcaat tttataactt tatgggctat gcacctattg
    16141 atcaaaatct agtcgatcag caaactgaaa cagccaagga aatgatcgaa gaatgtaaag
    16201 aatatgggaa atctgttgat tacacaaata tagaaggaat tattgcatat ggttctgttc
    16261 gtgaatccat ggcagtcaaa ttgccaaaaa aatatgagat cgatctaatc atggttgggc
    16321 agtcaggtct aaatgcagtc gaacgcttta tgacaggaag tgtagccagc tacgtgatac
    16381 gtcattcacc ttgtgatgtc ttgatcgttt ctgacgaaga agaacagcca agtaattaag
    16441 caagtggaac ttgtacgacc tttttaatca attaactaaa acagtaaagg gactgtgaca
    16501 aaagtcttgt cacagtccct tgttacgaat aaatggtgtt ccagaagagg cttcttcgga
    16561 aataaagcat gaaaaaaatt tcatgcagtg aatgcaattt tttgttaaga taaatctcag
    16621 caaaggataa tggaggaaag aacatgattt ttgcttataa caaagcacac gtcggagaca
    16681 ccttgatggt tattatagcc gacgataaag gaacagaaaa cactgttgaa cgcaaatgga
    16741 atgttgctcg gatcaaagat gaacaaggtc aagttgttgc ttggaacttt ttccatatct
    16801 ccgatcatct aacaatcgaa gggaacggcc aagtaagctt aacagatgag gaattagcga
    16861 aattgaatcg attgatcaaa gaagcaggat tcgaagaaca gcttgaagct gatcatgaac
    16921 cgaagatcgt tgtcgggtac gtaaaaacat gcgtcccaca tcctgattct gaccatttat
    16981 cgattactga gacagaagta gacaatggta cagtattgca aatcgtttgc ggtgcaccca
    17041 atatcgaagc tggacaaaaa gttgtcgttg caaaaccagg agctatgatg ccagatggaa
    17101 tgatgatctg gccaggaact ttgcgagggg tagatagcta tggaatgatc tgttccgctc
    17161 gtgaattgca tttgccaaat gctccagcaa aaaaaggaat cttagtattg cctgaggatg
    17221 ccgtagtcgg agaagcattt ccaaaataaa gaggttgtga caagtctttg tcacaacctc
    17281 ttttttatta attttcacta ttttgatttt gttttaatgc cgattgatcg atcgtcaatt
    17341 caacagtagt tgttttttct ttcgagcctt catagtaagt gattttgaca gaatctccca
    17401 cttttttctt atacaaagca gattgaagtt ctacaccaga agaaacttct ttgtcatcga
    17461 tcttagtaat gacgtcgtat tgtttcaatc cagctttttc agccggtgta gctgtttgga
    17521 catttgtcac gatgacaccg ttagttacag atgaaggaat cttcaagatt tgttcttgtt
    17581 gctgagtaga aacggcagat aagtcgacca ttgtgatacc tagagctgga cgtgtcactt
    17641 ttccgtcttt ttccagttga ttgatgatat tcactacatc gttacttgga atagcaaatc
    17701 ccattccttc tacgcttaca ttagaagtag attcagaagt acttgcgatc ttacttgagt
    17761 tgataccgat aacttgtcct tcgatattaa ctaaaggacc accagaattt ccagggttga
    17821 ttgctgcatc tgtttggatc gcattgatat tgactgtttc gttcgattca ttcgtacttg
    17881 tcacttgtcg gttcaaggaa gaaatgattc ctgaagtgac agaatttgca tattcagatc
    17941 ctagtgggga accaatcgca atcgcaggct caccaacctt cagagcactt gagtcaccaa
    18001 aagaggcaac tgtttcgact ttgtctgaat tgatcttcaa caccgctaaa tctgaataag
    18061 catctgttcc aactaattca gcttttacct tcgtaccgtc tttcatcaag acttcaagac
    18121 cttgctggcc atctactacg tgattattcg tgactacata agcagtattc ccgtcttttt
    18181 tgtagatcac gccgcttcct tcactataag cttccaaatt actatcatct gagctgctac
    18241 tttcttcttg ctgcccgaat agtccgccaa aaccgcttga ttggttttga ctttgtaagt
    18301 tgataacaga aacgacagcg tcttgaactt tatctaccgc tttggtgata tcagaatcta
    18361 cattgacttt gacattttcc acaactgttt caccggcaga attctgattg ccgcttgtag
    18421 cagtagaact attgttgcca gtgcccatcg ctgcataaaa aatgccagct gtcagtagtc
    18481 ctccaacgat ccctccaaca agccccagac ctaacttacg ccagaggcta ttatttttac
    18541 tttttttcat ctttggtgtc acattttttc tatccatgtg ttcctcctcc aattacattc
    18601 atttatctac tgttagtata gtcttatttg ttgactttag tctactttga gactgtgaac
    18661 tttttatgaa aaactttagg aaaaatcatt gttttcagat gaaaatattt gattttcttt
    18721 ttccacagat actgtgtaaa actacgcgga taggattgga aaaataaggg ataaaacata
    18781 tccacagcct gtgtataaag tggataaatt cttataaaac gtatgtttgc ctaatgaatg
    18841 tgatgaaata aggtaaaata acactgtttt ctgtggataa acctgtggat gttgtgcata
    18901 actgttgggg aaatcttttt aacaaaaata gccaaaataa acatatagac gaaaaaattg
    18961 attataataa acaaagtgag catgaagacc aaaggagaga aaacatgaat atcaaaatta
    19021 tctcagtagg aaaattaaaa gaaaaatacc tgatccaagg tatcaatgag tatgtcaaac
    19081 ggctgaatgc ctatgcaaaa atcgaattga tcgaagttcc tgacgaaaaa gccccggaga
    19141 atttaagcga agcgcaaatg agacaagtaa aagaaaaaga aggggaacgg atcttagcga
    19201 aaatcaaaga acaagaatac gtctatgcct tagcaattga agggaaaaat cctacaagtg
    19261 aatcttttgc taaacaaatc gaccaattag gtatccaagg aaaaagccac cttgtttttg
    19321 ttatcggcgg ctctttagga ctcagcgaag ccgtcatgaa aagaagcaat gctcagatct
    19381 cttttggaaa aatgacgtat ccacatcaat tgatgcgtct gatccttgtc gagcaaatct
    19441 accgtgcctt ccggatcaat gcgggggctc cgtatcataa ataatgatat ttaagattga
    19501 atgctcctga acactaagtt agcttttcat tgaaatttat atataaaaaa gttaacttga
    19561 aaatcgttga gaatttcaaa aaaataataa taa
//
LOCUS       DAZUJR010000056        19507 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.056, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000056 DAZUJR010000000
VERSION     DAZUJR010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19507
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.056"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(460..1089)
                     /gene="udk"
                     /locus_tag="ACG804_001897"
     CDS             complement(460..1089)
                     /gene="udk"
                     /locus_tag="ACG804_001897"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HFS4832822.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1173..1868)
                     /locus_tag="ACG804_001898"
     CDS             complement(1173..1868)
                     /locus_tag="ACG804_001898"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HFS4832823.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1881..2597)
                     /locus_tag="ACG804_001899"
     CDS             complement(1881..2597)
                     /locus_tag="ACG804_001899"
                     /EC_number="5.4.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0140098 - catalytic activity, acting on
                     RNA [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HFS4832824.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2927..3532
                     /locus_tag="ACG804_001900"
     CDS             2927..3532
                     /locus_tag="ACG804_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0008097 - 5S rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HFS4832825.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3857..4180
                     /locus_tag="ACG804_001901"
     CDS             3857..4180
                     /locus_tag="ACG804_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HFS4832826.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4362..5732
                     /locus_tag="ACG804_001902"
     CDS             4362..5732
                     /locus_tag="ACG804_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFS4832827.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5862..7163)
                     /locus_tag="ACG804_001903"
     CDS             complement(5862..7163)
                     /locus_tag="ACG804_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HFS4832828.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(7393..9384)
                     /locus_tag="ACG804_001904"
     CDS             complement(7393..9384)
                     /locus_tag="ACG804_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HFS4832829.1"
                     /translation="MATTHNTKKISMAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGL
                     SGINPDFVIGSVSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLII
                     PAMIGGAALLADGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFM
                     VQRFGTDIVGKAFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKL
                     GLFILGNIFLATTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQN
                     PEAQQIKNLNPFFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPR
                     LKIMYPGNSIGQMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALL
                     YFYLIQNGHSRWLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWE
                     QGNIIRESSTEDVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSI
                     LDKRPKRARVYWFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQ
                     VIHDLMKQGRLPKQPQRYSLTPGREVGDFQFVLIDKVVSNVTTLGKWQRQIMQAKLAI
                     KKIATSPETWFGLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9528..9794)
                     /locus_tag="ACG804_001905"
     CDS             complement(9528..9794)
                     /locus_tag="ACG804_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFS4832830.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10304..12430)
                     /gene="pnp"
                     /locus_tag="ACG804_001906"
     CDS             complement(10304..12430)
                     /gene="pnp"
                     /locus_tag="ACG804_001906"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HFS4832831.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12618..12887)
                     /gene="rpsO"
                     /locus_tag="ACG804_001907"
     CDS             complement(12618..12887)
                     /gene="rpsO"
                     /locus_tag="ACG804_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HFS4832832.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13138..13701
                     /gene="def"
                     /locus_tag="ACG804_001908"
     CDS             13138..13701
                     /gene="def"
                     /locus_tag="ACG804_001908"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFS4832833.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(13954..14475)
                     /locus_tag="ACG804_001909"
     CDS             complement(13954..14475)
                     /locus_tag="ACG804_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HFS4832834.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14478..15320)
                     /locus_tag="ACG804_001910"
     CDS             complement(14478..15320)
                     /locus_tag="ACG804_001910"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HFS4832835.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15313..16038)
                     /locus_tag="ACG804_001911"
     CDS             complement(15313..16038)
                     /locus_tag="ACG804_001911"
                     /EC_number="2.3.1.286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0034979 - NAD-dependent protein lysine
                     deacetylase activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HFS4832836.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16214..16510
                     /locus_tag="ACG804_001912"
     CDS             16214..16510
                     /locus_tag="ACG804_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832837.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     regulatory      16766..16940
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            17078..18670
                     /locus_tag="ACG804_001913"
     CDS             17078..18670
                     /locus_tag="ACG804_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015837 - amine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFS4832838.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18683..19423
                     /locus_tag="ACG804_001914"
     CDS             18683..19423
                     /locus_tag="ACG804_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFS4832839.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
BASE COUNT         5580 a         4001 c         3702 g         6224 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaaa cagttggctg gtgactgttc aaaaagcaga atccttgctt
      421 ttcaaacggt cgcagtccgt tcaactgttt cgctgcgcac tatttatggt ttaagaaact
      481 agctactttt gttgtaatca aatcaatagc aacgtggttt tctccgcctt ctggaacaat
      541 gatatccgca tagcgcttcg ttggttcgat aaattgatga tacatcggtt taacaactgt
      601 caaatattgt tcgatcacgg agtccaatgt gcgtccccgt tcttccatat cccgtttgat
      661 acgacgaatg atacgaatgt catcatctgt atctacgtat actttgatat ccatcaagtc
      721 acgcagacgt tcgtcttcta aaatcaggat tccttctaga atgatcactt cttttggttc
      781 ctgaatgatc gttgcctgac ttcttgtatg cgctacatag tcatacacgg gtttttcaat
      841 ggctttatag ttcagtaagt cgcctacatg ctgaatcagc agatcattat caaaggcaaa
      901 tgggtgatcg taatttgtgt tcaatcgttc ttcaaaactc aaatggctct gatccttgta
      961 ataagaatct tgttcaagca tcatgatgga atggtccggg aagttgttga aaatcgcacg
     1021 gctgacactt gtctttccgc ttccggatcc acccgtcaca ccaatgataa ttggcttgct
     1081 ttttgtcatt gactaaaacc tctttcgtat ccgttttttc attctaatct attatagcga
     1141 aaaaacacga aaatgctata tttttctgaa aattaatcct tttcaatttc caataatgaa
     1201 taaagttcct ctaatgaatc gattcgataa gtaggctgga tttcttcgat ttctggtaat
     1261 ttatttctat tgaaccaaat cgtatcgatc cctgccatat ttcctccttt gatatcagaa
     1321 gtcaaagaat caccaatgat cacagtttgc tttttatcaa aattaggaat gtgggaaaag
     1381 acatgatcaa aaaattcttt catcggcttt tgcgctccga cagcttctga gacaaagata
     1441 tccttgaagt aatcaagcat tcctgcatct gttaatcgcc gatgttgcgt gtgcgacaca
     1501 ccgttcgtca caatataaag atcagcatgc ggatggacct ttttcaggat ttctagactt
     1561 cctggaacaa gatcatgacc ttggttcaag tagtggcggt agcgtttttc catttgatca
     1621 ctatctactg ttttcccaaa ttgctggaaa agtaacccaa aacgactgcc tattatttct
     1681 tctcgtgata gtctgccttt ttcaaactcc tgccataaat gatgattcaa agccttatag
     1741 ctggtttcga tttctggtgt caatgtgatt ccttgttctg caaacaaagc acttaaagca
     1801 ttggcttcag ttaattgaaa atctaacaat gtatcatcta catcgaacaa taaagtttta
     1861 tatttcatct ttttgacctc ctatttaaaa taaatactta actttttcat ctctgctaat
     1921 gtcaacgatc gatactcgcc tactcctagc tgttcatcta attccaatgg tcccatgctt
     1981 agccgtttca atgcggtcac tttctttcct tgggctaaga acatcttttt gacttgatgg
     2041 aattttcctt cttggatcgt caataaaacc gtactttggt gcttgtctgc tttgagtatt
     2101 tttaaatcag ccggcttaca ttgataccca tcagcgaata cgattccatt ttcaaatgct
     2161 gttacgtctg ccggtgtcac cctttcgttc acaactactt gataagtctt tgaaaccttt
     2221 ttttctggaa gtagcatttc atatcccaat tgtccattcg aagtgatcag caatagtcct
     2281 gttgtatctc tatctagtct tcccactgga tataatggtt ggaaacgatc ggcacttgca
     2341 atcagatcga ttactgtcgt cttttctgga tctgatacag ctgtaacagc tttttcaggt
     2401 ttattgagaa gataatagga ctcatttgtt tctaagtgtt cacctgctac ttcgatttga
     2461 tgcagtaaac tatctacatt tcgattttgt cgaaattcga ctgtgccatc tatcatcact
     2521 tgcttcaaag caaacagccg cttcatttcc ttgcgtgtcg tttctaattt ttcttctatt
     2581 aatttatcta aacgcatgct gtttcctttc ttattactac taattaatta taccttgaat
     2641 attcttgctt gcaaatacat catcatagtt attccttgac ttaattaaca gttcacgtta
     2701 cggttaaata gtaaagtgaa ttggatttct catacacagc gtaatgacct ggtggagaaa
     2761 agttgaatcc tgactttcta aggggagatg cgcgcatctc tccttttgcg cttttttaag
     2821 cgccctgcct tcgatgatgt gcacgagatt agcctttaga attcacttaa ataaaatctg
     2881 tccgttacca aagcagacag tcacatttta aggaggaatt ttggttatgt cagtatcatt
     2941 agaagtaagt aaaagagaag tacgtccccg ttcattaaga aacaaacttc gtcacgaagg
     3001 gaaagttcca gctgttgttt atgggtataa agtagaaagt acccctatct cattcgatgg
     3061 tttgacacta agcaaattgt tgcgtgaaca tggagcgaac acagtcatca cgatggacat
     3121 cgatggacaa aaagtcaata cattggttca caagatccaa acgaacactt ttaccaatca
     3181 tttcgaacat gcagaatttc tatctgtaaa catgtcggaa gaaacagaag tcgaaacaga
     3241 agtcgttctt gttggcgaat cagtgggtgc taaatctggt ggagtgttag ctcaaaactt
     3301 gtatacagta gtcgtatctg ctacaccaga caaattgcct gaacgaattg aagttgacgt
     3361 gacaaacttg gaattaggtg attctattac agtagccgat cttccaaaaa acgacgatta
     3421 caaattcgtg accgacagtg aagagcaaat cgctgctgta gtcgctcaaa gtgaagaaga
     3481 aagcacaggt gaaggtggcg aaccagaagt gatcggttca acagaagaat aatactgaaa
     3541 caatcaggtg gtgttagaag cggcgggtca gcagctttta acacgccttt tttatttcta
     3601 atcgtttatt ttcatatggg gcttccactt ttgtaaatgg ctttacaaac gaaaaatcct
     3661 aatttaccaa gcttttcctc gcatactttt atcgtacctt tataaaaatt tatactttga
     3721 aaaaaagtat tcaattattg ttgcattttt cctgattctt tattagaatg aaccctcgtt
     3781 gaagtaagta tttctagttt atcctaggat taattataaa aataaaacat tcgttgattc
     3841 gaaggaggtt aaacagatgt ttgaaagttt tgatagcagc cgcaaccgtt acgcttcagt
     3901 tggtgtcgta tcaagtttgc cagatgaatt gattgacagt atatggttta ttattgacct
     3961 agatcttaag ggagtcattc cattagaaaa tatattaacc tttgatttga tcgaaaatcg
     4021 tggaaaagtg acgatgcatt tttctcaagc aggaagcaat gtggaaatgg atattgattt
     4081 gccgtttgcc tattcgaacc aatttcctgc tcaagtatac gcctatgatg acggtacgag
     4141 agaaacgatc cttttaccaa gtgagattag acaatattaa ggtgatagat aaacgtggat
     4201 gtcccttatt ttacagacca ggccaagttg ttgattcttt gactcaattc ttggcttctt
     4261 tttatggagt ttcataaatt atcattgatt tctaattggt attctcagga taaacgctat
     4321 atactactaa ctaaatttta aagatataag gagtttaaaa gatgcgcgat ttaacaaaag
     4381 gaagccccgc taaactgatt ttgatgttca ctgttccttt actgatcgga aatgtttttc
     4441 agcagttcta caatatgatc gatatgatca tcgtgggtca gacgctaggt aaaaatgcgc
     4501 tggcagcggt tggtgcaact ggaagcctga catttttgat cattggcttt gcccaaggtt
     4561 taacagctgg tttagccatt attaccgcac aacgttacgg tgcaaaagat tatcggggtc
     4621 tgaagaaaag ttttgctgct agtgttgtca ttagtcttgt cgtcactgtg attttaactg
     4681 tcctaagtct cctgtttatt cgtccgatgc ttcaattgat gcaaactcct cctgaaatac
     4741 ttgatcaagc acaaacattt atttcaatta ttttattagg gatctttgca tcagtcagtt
     4801 tcaatttgct ttctaatgtc attcgcgcac ttggtgacag ccgcacacca ctattctttc
     4861 tgatcattgc ggtcatcatc aacgtcgtac ttgatttgat ctttattatc tattttggca
     4921 tgggtgtgga aggtgcagct attgctacag taatcgcaca agtttcttcc agcgtactgt
     4981 gtctagtgta tatcaagaaa aaaatgcctt tgttacagtt acgcaaaaaa gatttcaaat
     5041 ttgaaaaaga agagtttgct gtacacctaa atgctgcttt gccaatggcg tttcaatctt
     5101 cgatcatcgc tgttggtgct atcgtgttac aagcagcact aaatagtcta gggacagatg
     5161 tcgtagctgc tcaagccgct gctggtcgta tcgaccaatt tgcaaatcag ccgatgatgt
     5221 catttggtat tgcaatggca actttcactg cacaaaacta tggtgcgaaa gaatatggcc
     5281 gaatcttgca aggggtacgt caaactttac tgatgagtgt cggatttagt ctcttagcag
     5341 gtgctatcgt cattttcttc ggtcatttct ttgttcaatt gtttgttagc ccatcagaaa
     5401 cacgtgtatt tgaattagca caaacctact tcaatatcaa tgggtctctt tactggatct
     5461 tagcagtcct gttcatttta cgctacacac ttcaagggct tggacaaagc aagatcccta
     5521 cgatcgccgg tatgatggaa ttgcttatgc gttcttttgc agctatcgtt cttacaggaa
     5581 tgtggggata cccaggagca gcagcagctt ctcctttagc ttggatcggt tctgttgccg
     5641 tgttgcttta ctcttatatg cgttcgatga aacaattgaa acacatgggt gaagaggaac
     5701 atttcacatt agaacatgca gaagcaagat agccttgatt aaaagaaatc gttgcggcta
     5761 aaaatgaaaa cttttattga aaatatcttc ttcgtttacc gaaaacaggt tttttagata
     5821 acaaaaaggc tgtgacaaaa aatgtcacag ccttttttct tttattctat ttttctttcc
     5881 gtggactcta ctttgaaata atcgatatgt gcatgctggt attctaatac cgtgaaacgg
     5941 aatgatgcaa tctcaatgat tgttcctgct tttatttctt tatatcggct agaagcaaag
     6001 cccgcaagtg tagtaaaatt cgtttcttca aactctggaa tctctacatg aaaataacgc
     6061 tggaaatcat ctaatgttag tttgccggag atgatataag agccatctga ctgttccgct
     6121 atcaatgctt cgtccaaatc tgtctcatct cggatttccc cgacgatttc ttctaaaata
     6181 tcttcaatcg tcactaagcc gcttgtccct ccgtattcat cttttaagat agcaatatgc
     6241 tttccctttt ttcgcatgat cgtcaataat ttttttatag ggatcgtttc agttgttacg
     6301 atcggctctt caatcaactg ttctactgtc agctggtcat ctttataaga ttgcttgatc
     6361 aaatctggca aggtgacata acctaaaaca ttgtcttttg attctaagat aaccggatag
     6421 cgagtatgtc cttgttcaat cgaagctttt atcgcttctt tgacggtttc tgaagcttcg
     6481 aatacttgca tggacgtacg gtctacttgt atatcttttg ccaaggtatc atcaaattca
     6541 aacacgtttt ccaaataatg atattcttct ttggtcaact ctcctttttc ataagaattc
     6601 aatgcgacta atgtcagctc ttcttgagac aatgtctctt ctccttcaga tacgagacgc
     6661 acacctaata gcttccctag ccctgcagct gaatgattca atacccaaat aaaaggaaac
     6721 attactttat aaaaataatg aagtggttta actacgaaca agacgacctt ctccgtattg
     6781 acgatactat agctcttagg aagcagttcg ccaataacca catcgatata cgtaactaaa
     6841 ataaatccca gcgccacaga gattgtactg ctaatagccg aactaaaagg tagtttaccg
     6901 atcactggtt ctagtaaagc cgcgacagat ccttcaccga cccacccgat gatcaaaccg
     6961 gttagcgtaa ttcctaattg actagctgat aaatagttat ctaaatggtg tgtaacatga
     7021 agagctagct tggcgttctt tacattttcc ttttctagtt gttccaatct tgatcgtctg
     7081 attttcacta aagcaaattc acttgctaca aaaaatgaag taattgcaat catcaaaaat
     7141 aaaataatga aattgataac catattctcc cgcctttctc tttttctatt gtaccctttt
     7201 tctacaaaaa gattgaaaat aatgcgtatt catatttagg aataaaaaag gagatgcggc
     7261 atttttcagc cacatctcct tatcacttca aaatcattgc gttacttgtt gctaaacagc
     7321 tttttcatga cctctgataa acggtgttca agtagctgac attcgacatt agttcaggtc
     7381 aaagcgctac tttcacaacc gctctttcaa ccatgttttc cgagtatttc caatgataag
     7441 cggaacagtt tcatgtttta cttcgctgta ctctagccca aaccatgttt ctggcgaggt
     7501 agcgattttt ttgattgcca gttttgcctg catgatttga cgttgccatt ttcctagagt
     7561 tgtcacattg gaaactactt tatcaatcag gacaaattgg aaatcgccaa cttctcgccc
     7621 tggtgtcaga gagtatcttt gtggctgttt tggcaaacgg ccttgtttca tcaaatcatg
     7681 gatgacttgg cgaacatata cgttgatttc ctgttggacc ctgaaaccta agaacagatt
     7741 cacttggaca ataaaatcag tgtccatcat atctacttga tattctttcg tatatggctc
     7801 atccgtcact tccacatgaa caaaccaata gactcgtgct cttttaggcc gtttatctaa
     7861 aatcgaatag atgaactgtc ggccaacttt atcttcagcc atatcaggaa ccaagaagac
     7921 cacatttgtc tgatagattg gtaaagaagt atcatcacgt aattctctaa gctgcgggat
     7981 ataatctctc aaagacacat cctcggttga cgattcgcga ataatgttcc cttgttccca
     8041 aataaacatc acgactaaga tgatcaaacc aatcagaacg gctacaaaac cgcctcggaa
     8101 gaatttgaca acacttgaga taaagaaaac gacttctatc gcaccgaaga aaaaggtaac
     8161 taaatatgca agccaacgag aatgcccatt ttggataaga taaaagtaaa gcagtgctgt
     8221 tgtcatcaac atcgtcacag tgatcgatag accgtaagca gcttccatat gatgagacgt
     8281 tcggaatgtg acaaccacta gagaacaggc gatccataaa atcagattga ctgctgggat
     8341 atacatttgc ccgatactgt tcccaggata catgatcttt aaccgaggca gcagtttcaa
     8401 cttgattgct tctgaaacta gcgtaaacga acctgtaatc aatgcttgcg aagcaatgac
     8461 tgcagcgact gttgcaaaag caacgccgat cacgatccaa ctttgaggca tcatttggaa
     8521 gaatggattc aggttcttga tttgctgtgc ttcagggttt tgataaacat tcaacaacca
     8581 cgcagcctgc ccaaaataat tgataaccaa acaaattttg acgtaaggcc agctcagacg
     8641 aatatttcgt ttgccgacat gtccaagatc ggaataaagc gcctctgcac ctgtcgtagc
     8701 caggaaaata tttccaagaa tgaacaagcc taatttgtta tctgcactaa aaagcagctg
     8761 gatagcataa taaggattca gtgcacggat aactgtccag tcttgactga agttcattaa
     8821 tcccattacg cctaaaaaag taaaccaagc gaacatgatt ggtccgaatg cttttccgac
     8881 aatatctgta ccaaagcgtt ggaccatgaa taaaacaaaa ataataacta aagtgataat
     8941 gacgatcacg ttctggttat taccgaaccg gtcaaaaaac tgcggaattc ctcgcaagcc
     9001 ttcaatcgca gtcgttaccg tcacagcagg ggtcaatacc ccatctgcta gtaaggcagc
     9061 tcctccgatc attgcaggaa tgatcaaata tttcccacct tttcggacaa gtgtgtagag
     9121 tgagaaaatt ccaccttcac catggttatc tgcattcaat gcaatcacga catatttgat
     9181 tgttgtcagt agagtcaatg tccaaaaaat caatgagact gatccgataa caaaatcagg
     9241 attgattcct gacaatccgc cattatcttc aacaatcgat ttcataacgt aaagcggact
     9301 tgtcccgatg tctccgtaga cgactcccat cgctacaagc aggccagcca ttgatatctt
     9361 tttggtattg tgcgttgttg ccacgttttt ccctcatttc ttgttatatg gatatccttt
     9421 aggtaagctt gaatgataga tgatattctt atccatgaca cccgctttcc taaattgctt
     9481 ctaattatcc aagtaacaca ctgaagtgtc aacttatttg aataaaatta ttctttcttt
     9541 ggacgttctc tgatacgtct tgccacaaat gaataaagag caaggcaaaa aattgcaccc
     9601 aataatgctg gtatcaaata aaaaccgccg agttccggtc ccagtggtcc tagtaaaaat
     9661 tcgccgagcc aactacctaa aaaaccgata atgatatttc cagatacgcc tcccgggact
     9721 tcctttccta aaattgcgcc agctatcaaa cctaatatac cgccgataaa taacgaccat
     9781 aaaaaattca gcatctcctt tccctccttt atccatattt ctcactttta ttttacgctt
     9841 tattcagaag gactccaaaa atatgcgcca agaaactcca gaaaaaaaga agttgtaaca
     9901 aaagtgttca gcttatttcc gtagaagctg cttctggaac accgtgaatc agaggttgtg
     9961 aaatcagcgg tttgacctga gtattagaga aacaaacgga aaaatagttc ctcatatttt
    10021 gccgtttttt gagctaatat cgagggacag ctgattgaac atcgtttatt ggagaggttg
    10081 taaaaaagct gttctgcatc aagtaataag aacagccaag taaaaacagc tcctaatgtt
    10141 tttaacttgg ctggacttat taccgcagat gcaagctttt gaacaccgtt tattcgaaaa
    10201 aaaaggactg tgacacggct tttgtcacag tccccttttt tcgaataatt attgtccccc
    10261 tgtcaccttc acgatcacaa gtacattatt cctatgaatt aaattatttt tcttcatttt
    10321 tcgttgaacc atcttcgttc aacattgctt ttcttgacag atttacgcgt ccttgtttat
    10381 cgatttcagt tactttcaca aggatctcat cacctagttt aacaacatct tcgactttat
    10441 tgacacgatc gtttgctaat tgggaaatat ggacaagtcc atcttttcct ttgatcaagt
    10501 tgacgaatgc accgaatttt tcgatacgga caactttccc tagataaact tcaccaactt
    10561 tgacttcttt ggtcaaatct tcgatgatct tgatagcttt tttgatcatt tctgcatcag
    10621 ctgaagcaat acttactttt ccatcttgat cgatatcgat tttcacacca gtttcatcga
    10681 tgattccgtt gatcgtatcg ccgcctttac cgataacatc tttgatttta gcaggttcga
    10741 tctggatcat ttcgattttt ggtgcatatt ggcttaattc ttcacgtgga gcagcaatcg
    10801 ttgaagtcaa ttcttctaag atttccatac gtgcttgttt tgcttgagtt aatgcttcag
    10861 ttaggatttg ttctgtgatt ccttgaatct tgatatccat ctgtaaagca gtgataccat
    10921 cttttgtacc ggcaacttta aagtccatat cgccaagatg atcttccagc ccttggatat
    10981 cagttaggat cgtatagttt tcaccatcag aaacaagtcc catcgcaata ccggcgactg
    11041 gcgctttgat tggtacacct gcatccatca atgctaatgt gccagcacag atacttgctt
    11101 gggaagaaga accatttgat tccaatactt ctgctactaa acggatcgta taaggaaatt
    11161 cttcttctga agggattact tgtgctaacg cacgttcacc taatgcgcca tgtccgattt
    11221 cccgacgccc tggagagcct gcacgtcctg tagaaccaac agaaaattga gggaaattgt
    11281 agtggtggat gaatcgtttg ctgacttcca cccctaaacc atcaatgatt tggtgctctc
    11341 ctagaggtgc gagtgtacaa gctgataaag cttgtgtttg tcctcgtgtg aacaaacctg
    11401 atccatgtac acgtggcaat aagctgacct ctgatgacaa tggacggatt tcatccaatt
    11461 tacgcccgtc aggacggatc ttatcgatgg tgatcaattc acgtacgaca tctttttcaa
    11521 gatcttctgt gatttgttta acttctttca acaagtgatc ttcatcttca tgacctgcaa
    11581 atttctcagc ataagcttcg cggatatcga tcttcacctg ctcgatatta tcttcgcgag
    11641 caagtttttc ttcagtcatt actgctgctt tcattgtagc gtaagaagca tcaaagattt
    11701 cttttttcaa tacttcatca acttgcagta aagtcacttc cattttttct ttccctactg
    11761 cttgaacgat ttcttcttgg aaagcaacta actctttgat agcgtcaaaa ccaaacagca
    11821 atgcaccaag catgtcttct tctgaaactt ctttcgcgcc gctttcaacc atattgatgg
    11881 cttgtttcgt tccggcaaca gtcaattcga tatctgtttg ttctgcttgt tctactgttg
    11941 gattcaagac gtactcgcca tttacacgac caacttctac gcctgcgatt gggccgtcaa
    12001 atgggatatc tgagattgat agtgctaaag aagaacctag cattgctgcc atagctggcg
    12061 agcagtctgt ttctacactc atcacgatgt tcgttacttg gacttcatta cggaagcctt
    12121 ctgcaaacat cgggcgaatt ggacggtcga tcaaacgggc agtcaatgtt gcttccgtac
    12181 ttggacggcc ttctcgtttg atgaaacctc cagggatttt ccctgctgca tacatttttt
    12241 cttcataatt gatcgttaat gggaaaaagt ctgtatcttt tgcttcttta gaggccacag
    12301 ctgcacttaa gactactgta tctccataac ggactaaaac ggctccgttt gcttgttttg
    12361 ctagctgacc gacttcgatt tgtaagggac ggccgcccca tgtcgttttg aatacttgtt
    12421 tttctgacat aacttctcct tttccttctc gtgaaagcaa gacgctacta aacaaatgaa
    12481 aactgccgaa agccgtcttt tgagcagctt tcatttggtt agtaggagtc catctagctt
    12541 gatcacggaa ttttacttaa ttgatatacg agtaaaaaaa gtgagattca tgtgaatccc
    12601 actctttttg actaaaatta acgacgcaag cctaaacgtt tgatcaattc gcggtaacgt
    12661 tgaacgtcag ttttacgtaa gtaagctaac aagttacggc ggtgaccaac ttttttcatt
    12721 aggccgcggt atgaatgatg gtcttttttg tgcacgcgtg catgttcatt caagtggttg
    12781 atttcttcag ttaatacagc gatttgtact tctggagaac cagtatcccc ttcatggcga
    12841 gcgtattcgt tgatgatttc attcttgcgt tcttttgaaa ttgccatttc tttcacctct
    12901 ttcgattatt cccctgcgac tgagtaaaac gttggtgatt cgcttaacca agtggcaggt
    12961 catgtgccta gagcacacag ctatacttta cctgaaaccg ggttgaaaat caagtagtta
    13021 atcattaaga aaaggtagtt ttcaaacaat cttactacta cttttccatt tttgtggtaa
    13081 actataatgc gaaaatagac ttgaaacaca gtcttttaag aaaggggtac atattccatg
    13141 attacaatgg atgatatcat tcgtgaagga aatccgacct tacgcgaagt tgcaaaagaa
    13201 gtttctcttc cattaagcga agaagatatc tctttaggaa aagagatgct tgagttctta
    13261 aaaaacagcc aagatccaat caaagctgaa gaactacact tacgaggcgg tgttggctta
    13321 gctgctcctc aattagatat ttctaaaaga atcattgctg ttcacgtacc aagtcctgac
    13381 ccagaggcag atggaccttc tctaagtact gttatgtata atcctaaaat tttgagccat
    13441 tctgttcaag atgcttgttt aggggaaggt gaaggctgtt tatctgttga tcgagaagta
    13501 ccaggatatg ttgttcgcca tgccaaaatc actgtgtctt attatgatat gaatggtgaa
    13561 aaacacaaga ttcgtttgaa gaattatgaa tcgatcgtcg ttcaacatga aatcgaccat
    13621 atcaacggtg tgatgttcta tgaccacatc aacgatcaaa atccatttgc actaaaagaa
    13681 ggcgtattgg tgatcgagta gagaattggc aggttccttc gatactatgc tacaagaaag
    13741 ctttataaaa aaggggagtg ctcaaaagct gcacttccct tttttatgtt tctccactaa
    13801 tcgaaattta gatagacatc tagaaatcgc aattccaaaa aattctgtgt attggatacg
    13861 catcttttct tattttttct tatttcttcc atatgggtgt ttatctcaga gatgatagaa
    13921 tagtttctag gataaaaagt agcagctacg atgttatcct tcgtagagga ttcctgcttc
    13981 agctagtttt tgtttgatgt ttttcagcat atgcttttct gggtagcgga tcgtatgcag
    14041 atggatgccg cctgttaatt cggataacaa agtagcatta cttttttgat aacgtctcat
    14101 aaaggaatcg atatcttgtg gcgttttgat gtgcaaagtt cctgctaact caccgtaaag
    14161 gggatgttcc acaattacat caatgatttc accaccattt tcaacgatta gtctcagttc
    14221 ttcttctgtt tgatcttttc catgctggac agcgatttta ctgatgtgcc cagtattggt
    14281 ttcttctgtt tcgaggatat aacctcttgc tgttgccacg atacttttac ctgcagctcg
    14341 tagtaaagca atatcgccta caatgatctg acggctgact ccaaaagttt tcgcaaactt
    14401 gctagcactc actggttttt ctgtatttgc caaggtttgc atgatttgtt ttcgccgtgt
    14461 ctctccttcg atcacactta ttcctccttc attttgtttt ggtattcgcg cgagtgtttc
    14521 atcaaatcaa catacgtgtc tgttattgtt tccttatatc ccttattttt cagcagacta
    14581 acaactttat ccaatacttg ctgctctctt tttgcatcat aaactgcttg gttttcttct
    14641 tttttcactt gtcctatttt agttaccgta tccattcttt tttctaataa agcaaccaac
    14701 tctcgatcga tcatatcgat cttatgacgt aatgtttcaa gagactcttc tgttagttct
    14761 tcctctactg tcttgatgat acgagcagga tttcctgcaa tcactacatt gtcgggaaaa
    14821 gatttggtca caaccgaacc tgcgccgact actacgttgt cccctagagt gacacccggc
    14881 gtgacgataa ctcctccgcc taaccaaaca ttattaccga ttttaatggg ttttgcgtac
    14941 tccagaccgc tgttacgttt cactggatgt agtggatgcg tcgccgtgta aagctggaca
    15001 ttcggagcga acatgcagtt atcaccgatt tcaatcgtgc tgacatctaa aaatgtacaa
    15061 ttgaaatttg cataaaaatt ctccccaaca aatatattat atccgtaatc aaaattgata
    15121 actggctcca tatagatttt tttccctgta cggccaaaag tctctttcaa caattgggat
    15181 cgcagttccg ctgattctgc ttggttgatg atttggcttt gacttcttgc aaacatacgg
    15241 tcggcaacca gctcaggatc attggcaaaa taaagctcgc ctgcaatcat tttttctttt
    15301 tcggttttga attcagtcat aatctgctcc taattcttgt atttttttga aaacaaccgc
    15361 tccgtcttct tgaataaacg tataaggctc cgctaaataa acaggcgttt gattgattac
    15421 taagattttg gctgacggct ggcgaaactg taccagatca caaaacggat gaacttgaaa
    15481 actcgttcca acaatgacga tcagctctgc ttggctgacg gcataagccg cctgctccat
    15541 gactccatct tgaaaccctt caccatataa cacgatgtct gggcgtattt gtcctccgca
    15601 tgcttgatgt ttgtcgctgt gaagatattc tttccagtct accgtttgtt gacattttcg
    15661 acaatgacat tgatacagac tcccatgaaa attgacgagt tgcgggcttt tagcctttgc
    15721 gtgcaaaccg tcgatgtttt gggaaacaac ccaaacattt ttttctttcg ctagatgtgc
    15781 tatttccaaa tgaatgatat tgggttttgc ttcaggatga taaatctttt tgacaaattg
    15841 atagaattta tccggttcat tcaccattgc ttgatgactc agcaagtatt ccggctgctc
    15901 catcccgtgg tagattcctg acaaagatcg atagtctggc actccagaag gtgtggatac
    15961 ccctgcaccg gtcaaaaatg taatttgctg ataagctaat atctcttttg ctgcttcgtc
    16021 tactgttaat tgtttcatgt tttgtcacct cactttccat tatagcccat actcgaacaa
    16081 atttattgtt gaaaagtcag aaaaatggga ataaaaaagt gttatgggca tttgagcaat
    16141 ttatcacaat gttcactgac aaaagaatga aaacgtgtta caatactgct gtataaaagt
    16201 gaggtgaatc gatatgttac cattctttat ttattggggc gttattctgg cttgtatcgc
    16261 ctggttagcg ttaagcgttt atttctctgt tttttatctt gtacgcaaag aaaatggaaa
    16321 tctttgggct tttgctttat tcaacgtgat tgccgcaatt gttttagcca ttacattagc
    16381 cgtatatcga acatggggct ggggaatcac ccaatactca agtttgattt atctaatatt
    16441 agccatttat ggcgtcgttg ttcttttgca agcgatccta ggacgtgagc caaagaaagc
    16501 ggcagcttaa atgatcgaga tggaactgga cacaggaaat tttctgttct agttcttttt
    16561 ttattgtatt acatacattt ttgtgtataa ttatactatc gtttgcaatg gatagatgat
    16621 tcacattttg attgtttttt cggtaaaagt aaagatttct atatttatca gtattttttc
    16681 aaaaaccagc agttatagat tgacaaagcc tctcgagtat cgtaaacttt ttttgtataa
    16741 ataactgaat acgagatgcc tcaatcaatg aggtagaggt cgcgagaatc attaaccctg
    16801 tggagtgaag caaacatgga gaagcaggaa tagggaggat cgccgaaatg tgcacttttt
    16861 tgcttggagt gtatgttggg acgcaagtta agagcttgcg gactgtctta gcagtgatgc
    16921 taagttgcgc tatgttttgt gagaggttta tcaccttatg gaattttagc ggccttttta
    16981 tatctataaa tcggtcgctt tttatttttt cagataaagc tttaccgcat ttcatctaga
    17041 ccgctcgtgt atcatataat cagaaaggga gaaaaaaatg aaaaaaaata tggtttcagt
    17101 tgccgtacta tttgcttttg tcttctcact attcagtgtg ggatctctgg caaatgcaga
    17161 tgaaaaaaca ccgagcgatg agtttcgcgt aggtatggag gctgggtatg cacccttcaa
    17221 ctggtctcaa caaacagatg agaataatgc cttgccaatt caaggccaaa atagttacgc
    17281 cggcggttat gatgttcaaa tcgctaaaaa agtagcagat ggtttaggga aaaaattagt
    17341 catcgtccaa acgaaatggg atggtctggc tcctgccctt caatcaggca agatcgacgc
    17401 gatcatcgcc ggaatgagcc ctactgctga acgacgaaaa gaaattgatt ttaccgatcc
    17461 ttattacgaa tcacaattag tagtagtagt tcaaaaagat agcaaatatg caaaagcaaa
    17521 aagtttagca gatctttctg gagcaaagat cactgctcag ttaaatacat tccactatac
    17581 tgtgatcgat cagataccag atgtgcagaa acaacaagca atggataatt tctcagcaat
    17641 gagaacagct ttagcttctg gaatgatcga tggttatgtc agcgaacgtc cggaaggtgt
    17701 aacggcaact agtgtgaaca aagacttgga aatgcttgaa ttcagcggtg cagatggctt
    17761 ccagacaaac ccggaagatg ttcagatttc tgttggtatg cgtaaaggcg acccggatat
    17821 ccaaaaagta aaccagattc tttctggcat ctctaacgat gaacgaacca aaattatgga
    17881 ccaagcagtc aaagatcagc ctgctgcaac tgatagtgaa gaaaaacctg gcatcatttc
    17941 tgatttcact acgatttgga aacaatacgg caatatgttc ttacgaggtg ctggacttac
    18001 cttgttcatc gcattgatcg ggacagttgt cggtactaca cttggattac tgattggtgt
    18061 cttccgttcg gtacctgaat caggaaatgc actgactcgc ttcttccaaa aaatcggaaa
    18121 tgcacttctt tctatctatg tcgaagtatt ccgcggaaca ccgatgatgg tacaagcaat
    18181 ggtcatcttc tacggtctgg cactcgcttt tggcatttca ttgaaccgaa cgattgccgc
    18241 tttgtttatt gtctctctca atactggagc ttacatgaca gagatcgttc gtggggggat
    18301 ttttgcagta gatgaagggc agttcgaagc tgcgcaagcc attggtatga cccatggcca
    18361 aacgatgaga aaagttgtta ttccacaagt tttacggaat atcttgccag caacaggaaa
    18421 tgagtttgtt atcaatatca aagatacagc agttttaagt gtaatcggcg tagctgattt
    18481 gttcttccaa ggaaactctg cttccggtgc gaatttccaa ttcttccaaa catttacgat
    18541 cgtcgggatc atctacttag tcatgacctt tacgatcacc agaatcctgc gggcggtaga
    18601 aaagaaaatc gatggtcctt cagcttatac caagcttgaa gaaatcgaca attcaaattt
    18661 gcaggaataa ggaggaagaa tcatgaatga aaaaattatt gaaatcaaac atctaagaaa
    18721 aagcttcggt gaaaatgaag tattgaaaga tatcagcgta acagtcaata aaggtgaagt
    18781 tgtgacgatc atcggttctt ccggttctgg taaatctact ttcttgcgct gtatcaattt
    18841 actggaaaaa ccaacaggcg gcgagatcat ttataatgga gaaaatgtat tagctcctaa
    18901 atataattta cctaaatatc gaacgaatct aggtatggtt ttccaatcct tcaacctgtt
    18961 caacaatatg aatgtcttgg aaaactgtat gtctggtcaa acaactgtcc tgaaacgaga
    19021 taaagaaact gccaaaaaag tagcaatcga aaatctggaa aaagttggta tggatcgtta
    19081 tatcgaagcc aaaccagcac aattatctgg tggacagaaa cagcgtgtcg caattgctcg
    19141 ggcattatca atgaatccag atgtattgct attcgacgaa cctacttcgg cgttagaccc
    19201 tgaaatggtt ggcgaagtgc ttaatacgat caaagactta gcacatactg gcttgacaat
    19261 gcttatcgtg acgcatgaga tggaatttgc aaaagatgta tctgaccgtg tcatttttat
    19321 ggataaaggt gtgattgcag aagaaggtac accagaagat atctttgtcc atccgaaaga
    19381 agaacgtaca aaagaattcc tttcacgtat tttaaatgct taggatcaat agctgattgg
    19441 gacaaagagc tgcggtgttt accgcagttc ttttttatga attactcata aaaggtaaat
    19501 ttctgaa
//
LOCUS       DAZUJR010000057        18564 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.057, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000057 DAZUJR010000000
VERSION     DAZUJR010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18564
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.057"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            6..305
                     /locus_tag="ACG804_001915"
     CDS             6..305
                     /locus_tag="ACG804_001915"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFS4832840.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="ACG804_001916"
     CDS             378..1739
                     /locus_tag="ACG804_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HFS4832841.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="ACG804_001917"
     CDS             1761..2021
                     /locus_tag="ACG804_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832842.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="ACG804_001918"
     CDS             2035..2787
                     /locus_tag="ACG804_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HFS4832843.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="ACG804_001919"
     CDS             complement(2881..3486)
                     /locus_tag="ACG804_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFS4832844.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="ACG804_001920"
     CDS             complement(3539..4513)
                     /locus_tag="ACG804_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HFS4832845.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5610)
                     /locus_tag="ACG804_001921"
     CDS             complement(4891..5610)
                     /locus_tag="ACG804_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFS4832846.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="ACG804_001922"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="ACG804_001922"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0019191 - cellobiose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFS4832847.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="ACG804_001923"
     CDS             7161..8558
                     /locus_tag="ACG804_001923"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFS4832848.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="ACG804_001924"
     CDS             8639..9079
                     /locus_tag="ACG804_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFS4832849.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="ACG804_001925"
     CDS             9227..9553
                     /locus_tag="ACG804_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFS4832850.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="ACG804_001926"
     CDS             9554..10303
                     /locus_tag="ACG804_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease prefix domain 1-containing protein"
                     /protein_id="HFS4832851.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="ACG804_001927"
     CDS             complement(10383..10838)
                     /locus_tag="ACG804_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFS4832852.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="ACG804_001928"
     CDS             complement(11265..11540)
                     /locus_tag="ACG804_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832853.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11834..12649
                     /gene="thiD"
                     /locus_tag="ACG804_001929"
     CDS             11834..12649
                     /gene="thiD"
                     /locus_tag="ACG804_001929"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HFS4832854.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(12978..14429)
                     /gene="cls"
                     /locus_tag="ACG804_001930"
     CDS             complement(12978..14429)
                     /gene="cls"
                     /locus_tag="ACG804_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFS4832855.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            14770..17436
                     /locus_tag="ACG804_001931"
     CDS             14770..17436
                     /locus_tag="ACG804_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFS4832856.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            17800..18552
                     /locus_tag="ACG804_001932"
     CDS             17800..18552
                     /locus_tag="ACG804_001932"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFS4832857.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
BASE COUNT         5964 a         3212 c         3832 g         5556 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaag
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagga tactgaaata tatataaatc aaatagtggt
    11641 tatttattat tagaatagcg aatacaaata aacgaccact attttctgat ttattgcaaa
    11701 tgttttttca aataaatttg attaccaaga aaaggtagtg gtatatttac tgagggatac
    11761 tttgaaaaac atatgataga aacagtaaca gtattatgaa aaatcttttt ataaaaatgg
    11821 aggaatcgat ttgatggaag atcagtatgt acaagcaatg acgatcgcag gatcagatag
    11881 cgatggaagc gcagggatgc aagcagatat gcatacattc tttacaagaa atgtttacgg
    11941 tgtttctgtc atgaccgcat gtgttgcagg taattcttac ggaatcggag caagtgtgac
    12001 attgccaaca gattttatcg acaaagaatt tgaactgatt gcgaaggact ttcaaatacg
    12061 tgcagctaaa acaggtatgc tagcagattc aaagttgatt gagacagttg taaaaaatta
    12121 ccaaaaatat gattttggac cattagtcgt ggatcccgta atcgtaacga aacatggaaa
    12181 tcttttacta gaagaatctg ctttgcaaag cttgaaagaa aagcttgtcc ctttggccga
    12241 agtactgaca cctaattttt atgaagcaga aaagctgact ggacggacat tagcagctga
    12301 agaagatttt gtgcaagcag caaaagaact gcaagatatg ggtgcaaaaa acgttatgat
    12361 caaaggacat catgctaaaa atgcgcagca agaaacagtc aatgactacg tattgttcga
    12421 atcaggaaaa tcattttggt taaatgcacc attttatcct accgaccgga tcaacggaac
    12481 tggcgattcg ctatctgcat gtattgcagc tgagttagcg aaaggaaaaa cagttgaaca
    12541 agcgatccga ttggcaaaag actatgtaaa ccgtgcaatt cgtgaagaaa taaatgtagg
    12601 gcacaaatat ggccccatca atcattgggc agctggtgaa ttagagtaaa agaaagaagt
    12661 tgtgaaaaag ttgccctgca tcaagtaata agaacagcca agtaaaaaca gcttcttatg
    12721 tttttaactt ggttggactt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    12781 aggtcgtgag cctgccgtcc agctccgagt cacaaggaac aagttcaaaa aacagcttct
    12841 catgtttgtt gaatattgtg acttgtgacc gaggagttgg caggagaaca ccgtttgttc
    12901 ggaagaaggg actgtgacaa gatttttgtc acagtccctt taatcttagt atatttttct
    12961 ctacttgaat aaaaaaatta taggattgga gaaaataatc gagaaatttg ttgcttgaat
    13021 aatagccagt tagacatttc cttgactgtt tcagttgtca tggatgaaca atgtgtctca
    13081 tcttctttga actgagtagc aagttcttct aaaaactcag gatcgtaaat gacagcactt
    13141 gtttcaaaat tcaatcggta gctacgaata tcttgatttg ctgaacctac catgcagatt
    13201 tcatcatcca ttatcaatgt ttttgcatgg aggaagccgt tctcatagac aaggatttgt
    13261 acattttcct tgatcagctg ccgagcataa tattgtgttg ctcgataaat aaaaggatga
    13321 tccggtttgt tgggaatcat gattttcaca tctacaccag aggcagttgc gatttttaaa
    13381 gcagcaatga cactttcatc aggaacaagg taaggtgtct gtatccaaac acgtttttta
    13441 gcagaagtaa tcaatttgat aaatgaaagc ttgatttgtt ccctttcgtt attcggtccg
    13501 cttgaaacaa gctggatgga tgtatcagca agcttagatt catctcgatc tgctttttta
    13561 aagaaataat tcaaatgata gccgaccttt ttttcttcag gtaccgagac gttccagtct
    13621 gttaagaagc gaagctggag caaagaagaa gcggcaccga aaatccgtat atgcgtatcg
    13681 cgccaatagc cgaatttttt tgttgtattt acatattgat tggcaatatt gaaaccaccg
    13741 gtataactaa tctttccatc gatcacaacg atttttcggt gatcatggta attcaatcgg
    13801 aaacgaagta atgccctttg tgaggtaaca aatgtatgga catgtccacc atttttgatt
    13861 agacgattga aatcttttgc ttttgtgcca tgagagccaa atgcatcata taatattcga
    13921 acttccacgc cttctgcggc tttttcttct aaaacatgta agacttgctg gccgatatta
    13981 tctgtcacaa atgcgtaata ttcgatatgg atcgaatgtt tggctttttt tagatcttga
    14041 agcagtgaat ccaatttctc ttgtccgtct gtgagaagag tgacagaatt cattcttgtc
    14101 agcggcatac gatttaatga agagaagaag tcaacaaatt gctgtttgtc tttatcgccc
    14161 atgtcaggat cgtaatgttc aatggtatct cctctaaaag actgaaagtt ttctaattct
    14221 ttcaagtcac tttgtcggag atagaatttt ttcttatccg ttaatccacg tccgaaaaat
    14281 aaatataata caaagcccac cccaggaagg gcaaacaata ctaagagcca tgcccaaatg
    14341 gctgctacat ctcggggttt gatcaaaata gccaccaaag caataagtgc atttaataga
    14401 taaagggcgg ttataatact agataccaca aaaatgttcc tccttacata caataacatt
    14461 agtatagcat gatagaagaa agaagcctac caaggtgaat atacttttca ctcctttcat
    14521 gaaaatgtag gtaaatcggg ctaaagtagt tgctttttgt aggttaataa ggtaggatat
    14581 tagtacagtt gaatatctcc ttaggggagt aaccggcaac gtttgttgcg ataatatcaa
    14641 cagtaagtta accaaatggt tttctggtat tgtatgaaat ggtgagacct aagacaaatg
    14701 cgtatttgtc ttaggtctct tttttttcag acaggactag ggccaagatc aaaaaatggg
    14761 ggatgaaatt tggaaaacaa ggaacaagca caacaagcgg tctataaaga aacgatcgac
    14821 tcgttgatgc agcaaacgca gagctcaacc gatggattga gcaccacgca agcgaaggaa
    14881 aaattagaaa gagatggctt gaaccagcta aaagaaaagc cgaagaagcc aacttggaaa
    14941 ttgttcttag aaactttcaa agatgcaatg gttatcgtat tgctgattgt cgcactgatt
    15001 cagatggtca tgggtgacta catcgaattc ttagttattt ttgcagtatt gatgttgaat
    15061 tctataatca gtgttgtcca aacaaaaaaa gcagaaggtt ctttagaagc gttgaaaaac
    15121 ctttcagcgc ccgatgctcg agtgattcgt gatggtaagg aaaaaacgat tccggcaaac
    15181 gaacttgtgg taggagatat cgtgttgtta gacgcaggcg attatgtacc tgctgatgga
    15241 cgtttactag atgcgggatc attaaaagta gatgaaggta tgctgacagg agagtcgact
    15301 tctgcagaaa aagaagtaac ggatatcaca agtacggtac caatcggaga tcgtacaaat
    15361 atggtattca gtggaacgat cgtaacttac ggacgcggta aattcttagt gacttcaact
    15421 gggaataata cggagatcgg acaagttgct ggccttttgg aatcaacaac tgagcaagtc
    15481 actccgttac aacgaggtct ggataaattc agtaaaaaac taagtttggc tattttggca
    15541 ttgtctttat tgattttagg tatccaactg tttcgtattt atcttggaga aggtacagga
    15601 gatatgactg cagatatcgt cagcgcagtg atgtttgccg tagccgtagc cgtagctgct
    15661 attccagaag cattacagtc tatcgtaaca atcgtgttat ctttgggaac gaataaaatg
    15721 gcaaaacgtc atgccattat tcggaagctt ccagcagttg aaacacttgg ttcgacaagt
    15781 atcatctgta cagataagac tggtacattg acacaaaaca aaatgacagt tgttgactac
    15841 tttttaggta atggcgatac tggggatttc acaaatgacc cttcaaaatg gacagctgac
    15901 gaacgtcgct tgatcgaaat cagtgtttta gcgaatgatg catcgatcag tgaagacggt
    15961 actaaattgg gcgaccctac ggaagtagcg tttatcgact ttagtgaaaa attaaaccag
    16021 ccttatcagg aaatccgaaa caactaccca agacaagcag aacttccttt tgactcagat
    16081 cgaaaattaa tgtctactgg acacacaatt gataacaaaa attacttgtt tgttaaaggc
    16141 ggaccagata tcgtcttcca acgcagtaaa aaagtattgc taaatggtga agtcgttccg
    16201 atgacggatg aattgatgaa aaaattccaa gagcaaaatg aagctttttc aacacgcgca
    16261 ttacgtgtac tagcttttgc ttaccgtcca cttgataatt ttgatttatc atttgaagat
    16321 gaagacgatt tgatccttgt tggtttgctt gctatgatcg atcctccacg tgctgaagtg
    16381 actcaggcgg taacagaagc aagaagtgca ggaatcaaaa caatcatgat tactggtgac
    16441 cacaaaacaa cagctgttgc tatcgcaaaa caaatcggga tttttgaaga aggaaacctg
    16501 gctttgaccg ggacggaact agatgaattg acagaagatc aactaaacga agttttagaa
    16561 aaagtcactg tttatgcacg tgtttcacct gagaataaaa ttcgtatcgt tcgtgcttgg
    16621 caaaataaag gtcatatctc agctatgaca ggtgatggtg taaatgacgc accagcattg
    16681 aaacaagcag acatcggaat tgctatggga acgggtacag atgtggcaaa agatgcagca
    16741 gcgatggtat tgacggatga taactttgct tctattgtca gcgcagtaga agtaggacgt
    16801 aatgtgtttg ataatatcaa gaaagctatt tcttatctat ttgcaggaaa tttaggtgcg
    16861 atcattgcga tcatctttgc cttagttgct gactggtcca atccatttac agcattacaa
    16921 ctgttgttca tcaatttagt caatgattca ctgccagcaa ttgcattagg tacagaaaaa
    16981 gctgaacctg ctacgatgaa ccgcccgcca agagatccaa attcaggaat ctttacggac
    17041 aaaacattga tttctgtaac gtatcgtggt gtgctgattg ggattgctgt tatctttgct
    17101 caatggcttg gcatgcagca ttcacctgaa ttcggtgtag ccatgtcatt ttcaacattg
    17161 atttggtgtc ggacattgca aacattccca gcacgttcaa acacacaaac agctatccaa
    17221 gcagggttct tctctaacag aagtgtctta ctagctgtag ttgtatgtag cgcgctttac
    17281 tgcttaacaa tgatcccagg actgaaagaa gtcttctcta tcccatcagc atttggattg
    17341 acagaagtct ttacatgtat gggaatcgca cttgtgacaa ttgttttgat ggaaatcact
    17401 aaattgatca ttgtacgagt acaaggaaat aaataaaacg aatcaacgag gttgtgagcc
    17461 tgccgtttaa ttctgagtca caaggtgcaa tttcaacaaa cagcttctca tgtttgttga
    17521 atattgtgac ttgtgaccga agagttggca ggagaacacc gtttaaggaa gaagttgtaa
    17581 aatcagcatt ttgagctaat actgagggtc atctgattgg acactgttta ttcggaaaga
    17641 gggactttga cacgactttg gtcacagtcc ctttttttat ttatgataga cggaaagcca
    17701 atcattttat tattcatcaa aagagataga atagataaaa gaggagaatg atttattccg
    17761 aaaagtgaaa acatataaca aaaaattaga ggaaatcaaa tgaatgaaaa agaatgggat
    17821 gaatttgctg aagaatatta tgaaatccag caagaatcgc aagtaactat tgctgaagat
    17881 gtaaaaaatt atctgaaaac ggagaaagtc ctgcctgctg aaacagcagc agacgttgct
    17941 ggaggatctg gcagatttct ttccttagca aaagaaatta atcgctatga tttgatcgat
    18001 ttttcttcag gaatgctaga aaatgcaaaa aaagaagcag aaaaaaatga gttgccaaat
    18061 gtttccttta tcaaacagtc gttagaagaa tttatccaat caaatgagac atatgaaatg
    18121 gtttttacag cagcaaatcc agcattggta catcttattc aattagaaaa attgatgaaa
    18181 aagtcaagca aatggtgcgt gataatcaga gtagtggaat caatcgatga tgttttttat
    18241 cctatcgaaa agcaactagg aatgatagaa gaagatccta atacatcgcc agttgtaatg
    18301 gatcaatttg aaacatactt aattgatgaa ggattcaaag tgaagaaaaa agattttact
    18361 tattttacac aggaatcaat tactgaagaa ttgatgaagc tatactatga cgcgtacgca
    18421 aaagatcctg ttgtgaccag gtacattcgc aaactattca gtgaaaaacg agaaatcctt
    18481 agtacgacta agctgaccta tagactgctc ctttggtccg cagataaaaa aagaaccttt
    18541 cacgactcgt gaagggttct tttt
//
LOCUS       DAZUJR010000058        18528 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.058, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000058 DAZUJR010000000
VERSION     DAZUJR010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.058"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            123..770
                     /locus_tag="ACG804_001933"
     CDS             123..770
                     /locus_tag="ACG804_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HFS4832858.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    899..1115
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1163..3808
                     /locus_tag="ACG804_001934"
     CDS             1163..3808
                     /locus_tag="ACG804_001934"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HFS4832859.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            4118..5431
                     /locus_tag="ACG804_001935"
     CDS             4118..5431
                     /locus_tag="ACG804_001935"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HFS4832860.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            5421..6074
                     /locus_tag="ACG804_001936"
     CDS             5421..6074
                     /locus_tag="ACG804_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFS4832861.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            6129..6821
                     /gene="radC"
                     /locus_tag="ACG804_001937"
     CDS             6129..6821
                     /gene="radC"
                     /locus_tag="ACG804_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HFS4832862.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            6971..7171
                     /locus_tag="ACG804_001938"
     CDS             6971..7171
                     /locus_tag="ACG804_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFS4832863.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(7425..9104)
                     /locus_tag="ACG804_001939"
     CDS             complement(7425..9104)
                     /locus_tag="ACG804_001939"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HFS4832864.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(9106..9318)
                     /locus_tag="ACG804_001940"
     CDS             complement(9106..9318)
                     /locus_tag="ACG804_001940"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit epsilon"
                     /protein_id="HFS4832865.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9711..11441
                     /gene="efrA"
                     /locus_tag="ACG804_001941"
     CDS             9711..11441
                     /gene="efrA"
                     /locus_tag="ACG804_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HFS4832866.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            11438..13198
                     /gene="efrB"
                     /locus_tag="ACG804_001942"
     CDS             11438..13198
                     /gene="efrB"
                     /locus_tag="ACG804_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HFS4832867.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            13293..13490
                     /locus_tag="ACG804_001943"
     CDS             13293..13490
                     /locus_tag="ACG804_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832868.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            13643..14128
                     /locus_tag="ACG804_001944"
     CDS             13643..14128
                     /locus_tag="ACG804_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HFS4832869.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(14232..14825)
                     /gene="clpP"
                     /locus_tag="ACG804_001945"
     CDS             complement(14232..14825)
                     /gene="clpP"
                     /locus_tag="ACG804_001945"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HFS4832870.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            15005..15532
                     /locus_tag="ACG804_001946"
     CDS             15005..15532
                     /locus_tag="ACG804_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832871.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            15623..16360
                     /locus_tag="ACG804_001947"
     CDS             15623..16360
                     /locus_tag="ACG804_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HFS4832872.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            16364..17281
                     /gene="miaA"
                     /locus_tag="ACG804_001948"
     CDS             16364..17281
                     /gene="miaA"
                     /locus_tag="ACG804_001948"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HFS4832873.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            17283..18512
                     /gene="hflX"
                     /locus_tag="ACG804_001949"
     CDS             17283..18512
                     /gene="hflX"
                     /locus_tag="ACG804_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HFS4832874.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT         5990 a         3205 c         4026 g         5307 t
ORIGIN      
        1 atgcaagctt ttgaacaccg ttttatttgt ctcacaccct tttccttcct acttgtaacc
       61 ttgctcccgt gttagaaaca tgttacacta aatatgtgaa attattaaca aggagcgtcg
      121 ttatgcgaga aaaaacagat acactgccaa aagcaactgc gaaaagatta cctttatatt
      181 tacgctactt gaagatgctg gatgactcag gtataagtag aatcaaatca aatgagttca
      241 gcgaaatcac ccaaattcct tctgcaacga tccgcagaga cttctcgcaa ttaggcgagc
      301 taggcagaag cggatatggc tatgatgtcc cttttcttat cgatgtattc aataatatcc
      361 ttaatactaa agaagaaaaa cgaatcgcat tagtaggata tggaaatctt ggcaaagcat
      421 tgaaacacaa caattttaga agaaatgaaa atctaaatat cgtgtgcgtc tttgataatg
      481 atccagcact gatcaatcga gtaattgatg gagaaatgat ctatccgatt gatcgtttcg
      541 cggagatagc caaagcaaaa aatgtgacag tagcaatctc tacggtacca agtaaatatt
      601 cacaatctgc tattgatgaa attgtcaaag gaaatgtaac cgctatactt aattttgcgc
      661 ctgacagagt aactgtccca gcttatgtca atgttcaata cattgatttg acaaccgagt
      721 tgcagacgct tatttacttt gatgagaatt actcagaagt tttttcttag gaaaatttga
      781 gtaggcttat tgatcttgcg agaactcgtc gtaattcttt caaaaatttt ttagtactaa
      841 atgaagtggt tttttcacga ccacttgttg actaaaaaaa aaaaccattg tagaatgaag
      901 cataacgctg aacaagagga gtaactggca cattcattct tagagagaga actatctgct
      961 gaaaggttct caatgacaac cagtgaaggt agcttgggag tttctgtctt gaatggagta
     1021 gagatagacg agtcgtgatc gttaactcac ttgagaggca ataatgattg attattgcaa
     1081 tttaggtggt accgcgtaaa tcatacgtcc tagaatacga aagtatttta ggacgttttt
     1141 tagtttaaag gaggaaaaca gcatgacgga agaaaataac ctatcaacaa aatataatcc
     1201 gcaagaagtt gaagctggac gttatcagca ttggttagaa caagatttgt ttaaaccgag
     1261 cggagataaa aaagcaaaac cttattcaat cgtaatcccg cccccaaatg ttactggaaa
     1321 acttcattta gggcatgctt gggatacgac cttgcaagat atgctgattc gtcaaaagag
     1381 aatgcaagga tatgatactt tatggctgcc tggtatggac catgcaggaa tcgcgacaca
     1441 agcaaaagta gaagcgaagc ttagagagca agggatttct cgttatgatc taggtcgtga
     1501 aaagttcatc gatcaagtgt gggaatggaa agaagagtat gcgagccaca tccgcgaaca
     1561 gtgggctaaa atgggcttat ctttagatta cagtagggaa cgttttacat tagatgatgg
     1621 attatctgaa gcagtacgta aagtttttgt taccttatac gaaaaaggtt tgatttatcg
     1681 tggtgaatat atcatcaact gggatcctca agcacgaaca gctctatctg atatcgaagt
     1741 tattcataaa gatatcgaag gcgcctttta tcatatgagc tatgaactag cagatggatc
     1801 aggcgtagta gaaattgcga caacccgtcc agaaacgatg ttgggagata cggcgattgc
     1861 tgttcatcca gaagacgagc gttatcaagc gctcatcggc aaaaaagtga ttctaccttt
     1921 agtcaataaa caaatcccaa tcattgcaga tgaatatgta gatatggaat tcgggacagg
     1981 tgtagtaaaa atcactccag cacatgatcc aaacgacttt gaggtaggta atcgtcatga
     2041 tcttccacgc gtaaatgtta tggatgatga tggtacgatg aatgaactag caggaaaata
     2101 tgctggaatg gaacgttttg ctgctcgtaa agcaatcgtg caagatctga aagaaatcgg
     2161 tcgattgatt aaaatcgata cgatgatcca cagtgtgggt cattccgagc ggacaggtgt
     2221 cgttgttgaa cctcggctgt ctactcaatg gtttgtaaaa atggcgccgt tagcgaaaaa
     2281 agccattgat aaccaagaaa cagatcaagc agtggaattc ttccctccaa gattcaatca
     2341 aacgttttta cgttggatgg aaaatgtcca tgattgggta atctcacgac aattatggtg
     2401 gggacatcaa attcctgcat ggtatcacaa agaaacaggt gaaatgtatg tagggatgga
     2461 agcaccagcg gatagtgaaa actgggtaca agatcctgat gttttagaca cttggtttag
     2521 ttcagctttg tggcctttct caacaatggg ctggccagat acggaaagcg aagattataa
     2581 gcgatacttc cctactagca ctttagtaac cggttatgac atcattttct tctgggtaag
     2641 cagaatgatt ttccaaagct tggaatttac tggcgaacgt ccatttgaga atgtcttgat
     2701 tcatggattg attcgtgacg aacaagggcg gaagatgagt aaatcattag gtaatggaat
     2761 cgatccgatg gaagtaatcg aaaagtatgg agcagatgct ctccgctggt tcttatcgaa
     2821 tggttctgca ccaggacaag atgtccgctt cagctatgaa aaaatggatg cttcttggaa
     2881 ctttatcaac aaaatctgga atgcttcacg tttcgttatc atgaatatcg aaggaatgac
     2941 cgtagaagag atcgatttat ctggagaaaa atcagtggct gaccggtgga tccttactcg
     3001 tttgaatgaa acgatcgaac gagtaactga gctatttgat cgttttgaat ttggtgaagc
     3061 aggtcgacaa ctgtataact ttatctggga tgatttttgt gactggtaca tcgaaatgag
     3121 taaagaagta ctttatggag atgatgctgt ttcaaaacaa accacccgta gcatcttagt
     3181 ccatacactt gatcagatcc tacgtttatt gcatccaatc atgccattcg ttacagaaga
     3241 aatatgggaa catattcctc atcagggaaa ttctctagta gtggcagaat atcctgttgt
     3301 acgtccagag tttgatgatg aaacagcttc taaagggatg gaagtattga aagaattgat
     3361 tcgagccgtt cgaaatattc gttcagaagt gaatacacca ttgtctaaac caattacgtt
     3421 gctaattaaa acaaacgatg ctaaaatcga tcaattttta gttgaaaata caagctatat
     3481 cgaacgcttc tgtaatcccg aagagttgac gatatcaagt gagatcactg cgccagatct
     3541 agcgatgtca gctgttctga caggtgcaga aatcttcttg ccgttagcag gattgatcaa
     3601 tattgaagaa gaaatcaaac gattagaaaa agaactggaa aagtggacaa gcgaagtaaa
     3661 acgtgtccaa ggaaaacttt ctaatgaacg ttttgtttct aacgcgccgg aagaagtagt
     3721 agaggcagag cgtgcaaaag aaaaagatta tttagagaag caaacggctg tcaaagaacg
     3781 aatcgaaagt ttgcgtacta ttcaataaga atagaaaaag agagtgtgaa atcagctagc
     3841 tattactaaa agctagctga ttgaacatcg ttacaggaaa gagtttgagc ctcactctta
     3901 gcttcgattc ataaggagat gtgacataaa ttttgtcgca tctctttttt agtctactct
     3961 tattatgtag gagaaggagg gaggtggatc atgtatcaag agtcaataaa gtagttgata
     4021 aaatcgttcc tctctctgtt tcttttctct ttgtcatact tttatttttc ttatgtgttc
     4081 tatttgttat aataaaagag aaatggggga attgttgatg acgattgaag aagcaataga
     4141 atggatccat agtcgattac catttggttc acgtcctggc cttgaccgag tcgaagcttt
     4201 attagaagtg gtagggcatc cagagagaaa agtaaaaacg atccatatcg ctggaacaaa
     4261 cggaaaaggt tctactgtag cttatttgag aagcctatta gaagaggctg ggctgacagt
     4321 aggtacattt acttcacctt atatcgaaac gttcaatgaa cggatcgcaa tcaatggcaa
     4381 aagcattcca gacaatgatt tgatccagct tgtaaaaaaa tatcagccac tgatcaaaca
     4441 acttgatcaa tttgaagcag tagctggtat tactgaattc gagacattaa cagcaatggc
     4501 atttgattat tttttgatga agaaagtgga cgtagcgatt atcgaagttg gcttaggcgg
     4561 cttattggat tctaccaatg tagctgtacc aatgctgacg ggaataacaa cgattggact
     4621 tgatcatacc gaaatacttg gagatacaat tgaagaaatc gctgcacaaa aagctggaat
     4681 catcaaacaa ggcgttccag tagtaacagg aaatattgcc ccagaagctt ttactgtcat
     4741 ccaacaaaca gctaaagcaa aaaatgcacc gctttatgta tacggggaaa attataaaat
     4801 aaactatctg catcctgatg agatgtgggg agaagtattt gaatttttta atgaaatagg
     4861 aaagatccct caattaacca ctccgctttt agggcaacat caagctgaaa atgcaggagt
     4921 agccatcgaa ttgtattttg tttactgtca attggaaaag ctgcctttcc gagaaaaaga
     4981 tgttttgaag ggattgaaga aatctcgatg gccaggaaga atggagcgtt tgagtaacga
     5041 gccattagtt gttttagatg gtgcccataa tacgcatgca atgaaccggc ttgttgagaa
     5101 tttgaaaaaa gaattcaaag gatatcaaat caacattttg ttttccgcct tacgaactaa
     5161 aaatgttaga gaaatgctag aacgattgca gcaagtacca aatgtccata tttatttgac
     5221 gacctttgaa catccaaaag ccatcgaatt aagtgaagta tcagatttag caagtgagag
     5281 agtatcaatc gtttcattgt ggcaattcgg attagcagat atattggaaa agatgacaaa
     5341 tgaagacgta ttagttgtga ccggttcact ttatttcatt tcagaagttc gccatttatt
     5401 aatacaatta ggaggagatc atgaagtata atgcagtgat ttttgacatg gatggtttgc
     5461 tgttcgacac agagttagtg tattacgaag ccacacaagt agtagcagac aagatgggtt
     5521 ttccttatga taaagacctg tatttaaaat tcttaggtgt ttcagatgaa gaagtatggg
     5581 cgaattatca tatgattttc tcggaatttg gcaaaacaag tgtacaaaga ttcatagatg
     5641 attcatacca ggaaacgctt gaacgttttt cgcaaggagc ggtacaaatg aagcccggtg
     5701 tgttggaact cctctctttt ttagaagaac atcagattcc caaagttgtc gcttccagta
     5761 accaacgagc agtcattgaa cttttattga agaagaacaa tctgtttgaa cgatttgaga
     5821 cgattgtttc tgcagaaaat gttcaacgag caaaaccaga cccagaaatt ttcttgttag
     5881 ctaatcagaa gctaggtaca gcgaagaaag aaacattgat tttagaagat tcacaaaatg
     5941 gtattttagc agcttctgcg gctgagatcc cggtagtcat ggtaccagat ctgcttccac
     6001 catcccaaga attgatcaaa aaaacagctg gggttgtttc ttctttacat gaaatccctg
     6061 cattgttaaa ataaaaatcc atctcttttc gtatcttatt ttagataaga tagaaaggag
     6121 atgttttttt gggaaaacga ttgatcaaag aagtacctac tagctcttta ccaagggaac
     6181 gtatggaaat ttatggcgcg gaagctttat cggatcagga gcttttggca atcttactgc
     6241 gtaccggtca acacccttat agtgtgatgt cgattgctgg aaatctgtta aaaacgtttg
     6301 gaggactggc ctctttacga caggctactt tgcatgagtt agaagagatt cgagggatag
     6361 gacgcgtgaa agcaatcgaa atcaaagcct tgatcgaatt aggtcgacga attcagacgg
     6421 atcatgaaag agcggctcca ccggttcgta ccagctacga attggcccag caattgattc
     6481 tggaaatgaa agatcacaaa caagaacatt tggtttgtat ttatttggac acgaagaatc
     6541 aagtgatctt aaaaaaaaca gtgttcatcg gttcgctgaa tcagtcagtc gctcatccta
     6601 gagaaatttt ccattatgct gtacgttatt gtgcagcaag gatcgtttta gcgcataatc
     6661 atccttctgg taatgttatt ccatcgcagc aggatatgaa ttttaccaaa aggatacaaa
     6721 agtgtggaga aatgatgggg atcactgtac tggaccactt gatcatcgga cgcaaacgat
     6781 attttagttt gagagaagaa ggaatgatgg aagagaagta agttgctttc ttgcaaaaaa
     6841 aatgaagcaa gtgtacaatt atattgtaat tttgtttggg aatagaagtt gaaacatctg
     6901 ttgcacctct atcgtacacg agcaatgtta caatttaaat tagtgctttt ggcacgagga
     6961 ggatattatt atggaaaacg gaacagtaaa atggttcaac gctgaaaaag gatttggatt
     7021 tatctcacgt gaagatggaa gcgacgtatt cgttcacttc tcagctatcc aaggtgacgg
     7081 attcaaaaca ttagaagaag gtcaagcagt gactttcgac gttgaagaat cagaccgcgg
     7141 cccacaagct gcaaacgttg taaaagctta attttatctg taaatcaaat tgatggtaga
     7201 catcaatttt tacgagagaa caaagcgagt aacaaaaata cctgccacaa gagacaattt
     7261 ctcttgtggc aggtattttt ttgtatgaaa aagtaaataa atttaagagg ctatgaaaga
     7321 gccaccttgt atcaaggaat aagaacaaac aaaaatggct tctcatgttt ttcatttgtt
     7381 ttctcttata ttcaggacaa ggtgctgatt tcataacctc ttatttattc ttcatctggt
     7441 gtcattacca ttggcaaaat cattggatgt ctttctgtac gttcgaataa gaaaggctga
     7501 agcgcgccag tcatcgcttc tttcaattta tattctgaac agtcaggtcc attcaaacat
     7561 tctcttaaag cgtggaataa gattcgctga gcttcattga tcatttctcc tgattctcgc
     7621 atgtagacaa atccacgaga gagaatatct ggaccagcca agatttcttt tttcttgata
     7681 tccactgtcg cgacagctaa tacaagacct tcttctgaaa gcaggtgacg gtcacgtaaa
     7741 acgacattac caatatcacc gatcccgcta ccatcgatat acacatctcc agccacaaaa
     7801 tgcccagcag gacgcgcaga atcgctagtt aacgctaaaa catcgccatt ttccatgatg
     7861 aagcagtttt ctgcaggaac acctacatct tgtgctagag aagcatgtac tttcaacatg
     7921 cggaattctc cgtggacagg aataaaatat tttggcttca tcaaacgaag cattaatttt
     7981 tgttcttctt gtccaccgtg accggaagta tggatgttat tgatttttcc gtgaatcact
     8041 tctgcaccag cttcagacag caaattgatc aaatgattga cacttgttgt attaccagga
     8101 ataggtgaac ttgaaaagat cactgtatcg tctggctgga tttggatttg acggtgagta
     8161 ccattcgcga tgcggctcaa cgcggccatc gcttctcctt gagaacctgt acataggatc
     8221 atcgtttcat tggcaggcaa gcgattgatt tcgtgtgcat ctacaaatgt gccgtctgga
     8281 actttgatat atcctaaacg ttgaccgttg acgatggcat tttccatgct tcgtccgaaa
     8341 acagcgattt tacgaccagt tgccacagcg gcatctgctg cttgctgcaa acggaagatg
     8401 ttagaagcaa agctggcaaa aatgatacgt ccttcgattt ttgaaaagat cttcaaaata
     8461 gaatgcccaa tcgttttttc tgatttagta aatgttggaa tctcagcatt tgtactatca
     8521 gataaaaggc acaagactcc ttcttccccg atacgagcca ttttatgcaa gtttgctggt
     8581 tcgccaacag gagtgaaatc gaatttgaag tctccagtcg ctacgatatt tccagaaggt
     8641 gttttcacca cgatccctaa tgcatctggg atactatggg tcgttctgaa aaagctgaca
     8701 gaagtctttc taaaacggat gatcgtatct tcattgatct catggagctc tgcatctcga
     8761 agcaagccat gctcatctaa tttgtttgtg atcaacgcta atgcgagagg accagcatag
     8821 ataggaatat ttgcttgttt cagcaagtag ggtattccgc cgatgtggtc ttcgtgcccg
     8881 tgagtaatca ccaaggcttt tactttgtgt aagttttgta tgatgtagct gtagtcggga
     8941 atgacatagt caattccaag taaatcgtct tccgggaatt tgatcccggc atcaatcaaa
     9001 atgatttcat cttggaattg taccccatac gtatttttcc cgatttcacc taatccacca
     9061 atagcaaaga cgcctgtctc gttatttttg atggaaagtt tcatattaaa actccactaa
     9121 tgagaaatca gcattttctt tttcgtactc tagatgactt ccttctagaa gttgaacgaa
     9181 ttcaatattg tatggggtat tttcttccac acgttggcga gcgtctacat cgctttttgc
     9241 ctcaatgtaa agagattttg tttcttcccg tttagggttg cgtacttttg tttcttgata
     9301 ataaacttta tagatcattg ttttgtctcc tttatctgcg taaagcagtg atttagctag
     9361 ttgatttttt tagacaacac aaaacgaggg gacaagccac ctggtttttc atatgctttg
     9421 actagaatac tggattcgag tcaaagagac aagcctcgtt tttgcttatc tgttcggata
     9481 ttttttcaac cgtaccttct gtataaaaaa tatacaacaa ttaattgtta ttctagcata
     9541 aaacagcaaa taagtataga aatcaactag attgaaagaa aaaatcaatg tttatcatcc
     9601 cgctataatc ataatgactt ttttatgaga gaagtgttct attaataggc tcgttgtgct
     9661 atcattttta gtaatgaaaa tgtaacaaaa gattaaaagg agatgagaaa gtgaaactaa
     9721 tgtggcatta taccatgcgt tataagaaat tcttgttttt caatttcata tgcgtatttg
     9781 gttttatttt gattgaatta ggacttccta cgattttagc acgtatgatc gatgtaggaa
     9841 tccgcaatga tgattttgat tatgtgaagc aacaagggat atttatgatc gttattactg
     9901 taatcggtat tattttgaat atcttgttag gttattttgg ttcgaggatt acgactaata
     9961 tcgtagcaga tattcgagat gatttgttcg aaaagatcca aagttattcg catcaggaat
    10021 acgaaaatct aggcgtatct tcattgatca ctcgtacaac aaacgatgct tatcagatca
    10081 tgttgttcct gcaaaatatt ttacgtatcg gttttatggc accaatgatg ttcattgtca
    10141 gtttgtacat ggtcatgcgt acaagtgtga cactcagttt gtatgtagta ggtgcattac
    10201 ctttactatt attggcagtc gtagcgattg ctaaggtgtc tgaaccgtta tctaaaaagc
    10261 aacaaaaaaa cttagataaa atcaacagta tcttgcggga aaatctttca ggattgcgtg
    10321 tgattcgtgc attcgtcaat gaaaagtttg aagaaaaacg ttttgctgta gtcaatgaga
    10381 attatgcttc tagttcaaaa agcttattcc gtttgatggc tgttgcacaa ccgggttttt
    10441 atttcttatt taatatcgta atggtattga tcatctggag cggggcagtg caaatcgatg
    10501 caggcgagct tcgtgtagga gatttgattg cgtttatcga gtatatattc catgccttgt
    10561 tctcattcat gttatttgct agtgtgttca tgatgtatcc aagagcagct gtttcagctg
    10621 gacgtatcca agaagcccta gatgccaaac cttcgattgt agaagatcca aatggtatat
    10681 ctgatacaaa aactaaaggg tatatcgaat ttcaaaatgt aacatttgct tatccaggcc
    10741 attcgcaaga gccagtgata cgaaatgtca gttttacagc ctctccagga gagaccgttg
    10801 cttttattgg aagtaccggt agcggaaaat ctacgttgat ccaattgatc cctcgctttt
    10861 atgatgtgag tgaaggaaag atcttgatcg atggagtaga cgtgagagat tatcggctaa
    10921 gcaagttgcg agataagatt gggtttattc cgcaaaaagc gctgctattt actggaacga
    10981 ttgcagataa tttgcgatac gggaaagaag atgctacgca agaagaaatg gaacgtgcag
    11041 ctgagattgc tcaagcttca gaattcattt ctcgaaaacc agatggattt aatgaacatt
    11101 tatcagaagg tggttccaat ttttcaggtg gacaaaaaca acgattggca atagccagag
    11161 ccatcatacg ccgtccggaa atctatattt ttgatgacag cttttctgca ttagattatc
    11221 aaacggatgc gaagttacgt gctcgtctga aaaaagaaac gacagaatct actgtattga
    11281 tcgtagcaca acgtgtggga acgatcatgc atgcagataa gatcatcgta ttaaatgaag
    11341 gagaagtcgt cggtatgggg acgcatcggg agttgttgga aaaatgcccg atttattatg
    11401 atattgccgc ttctcaatta tcaaaggagg aattagcatg aaaaaaacct tttcttcctt
    11461 aaaacgttta gctcgatata tcagaccgta tcgtgagact tttcttttag tgatcctatt
    11521 tacagttctg acagtggctt tcaacgtggc tttgccatat gttacaggac ttcctactac
    11581 agaaatcagc cgtaatattg ccaatggcga atcaatcaat ttttcttata tattcaaatg
    11641 tctcatttgg atcacagttg ttggaatagg gtattgtatt tcgcaattac tttctggtgt
    11701 tttgatgaca aatgtcgttc aaagtgccat gcatgatttg agaagagaca tagaagaaaa
    11761 aatcaatcgt cttccggttt catatttcga taaaaaccag caaggaaata ttttgtctcg
    11821 tgtgacgaat gatgtagatg cagtcagcgg tgctttacaa caagctttta ttggtatcgt
    11881 aaatgcgata ttgggaatta cgttggctgc agcaatgatg ttttatatcc agccgatgat
    11941 ggcgctgatc tctatgatca tgattccaac atcgatctgg atctcaaaac gagtgatcaa
    12001 tgcttcgcag aaatattttc aaagcatgca gaattctctt ggtgagctaa acggctacgt
    12061 ccaagaaaat atgacaggtt ttagtgtatt gaaagtatat ggacgcgaaa aagaaacatt
    12121 ggaaggattc aaaaaagtta atcacagctt gaaatacttt gggtttcgtg cagcattcat
    12181 ttctggcttg atgatgcctc tagttcaatt aactgcctat gctacttata ttggtatggc
    12241 tgttctagga agcttttatg ttattactgg ggcgatcgtt gtcggtcaac tacaagcatt
    12301 catccaatat atttggcaaa tcagtcagcc aatggggaac gtgacacaat tgtcttcagt
    12361 tttgcaaagt gcatcagcgg caacgaaacg tgtattcgag attttagatg agccagaaga
    12421 aaaagaaaac aaagtagatg cttcactgcc agaaacgatt ttaggagatg tgacattcga
    12481 tcatgtcgat tttgcatatg atccgaagaa accattaatc caagatttga attttgaagt
    12541 gaaagctggt caaaccgtag ctgtggtcgg tccgaccggt gccggcaaga cgacattgat
    12601 caatctattg atgcgttttt atgacgtaga caaaggagca ataaggattg atggaatcga
    12661 caccaaatca atgagtcgca gtgatgtgcg ttcgctattt ggtatggtct tgcaagatgc
    12721 atggctttat caaggaacga ttgcagataa tatccgcttc ggaaagcttg atgcgacaga
    12781 ttatgaagta gttgatgctg cgaaaacagc aaacgtagat cattttatcc gaacgatgcc
    12841 agatggatat gatatggcca tcaattctga gggagacaat gtgtctttag gacaaaaaca
    12901 gttgctgacg attgcccgag cagtggtctc cgatcctaaa atcttgattt tagatgaagc
    12961 aacaagttca gtagacaccc gtttagaagc gttgattcaa aaagcaatgg atcgcgtgat
    13021 ggagggacgg acaagtttcg tcatcgctca ccgtttatcg acaatccgtg atgcagatct
    13081 gattctagtg atggatcaag gtcagatcat tgaaaaagga acgcatgaga gtttattggc
    13141 acaaggtgga ttttatgaaa aactgtataa cagccaattt gctgaggaag cagaataagt
    13201 catataagaa taaaacagtt taaaacttat tttttgttct ctattcttga taatggtaaa
    13261 gtaaagttat caagaaaagt gaggacacgg agatggaaca gtttttaaat gaaaaaatta
    13321 ctgaagccaa aagagaagtt gatcgtttaa cgcacgtctg tcagacgaag ccttttgatt
    13381 cagctgattt ttttgaaaat gagtttcaaa tcgaacgctt ggcagcacaa atagaagtgt
    13441 acgaattaat tttaaaaaaa gtaatagaag aaaatataga tgtacaataa aaacaggtaa
    13501 aacgtcagtt accagatact gtaaatagac atctggcctg agcaggtttt acctgttttt
    13561 tttcttatga aataaatata tgctatgata cctttattca ataggattag tttctacaaa
    13621 aaatgaaagg agaaaaataa atatggaacg gtttatagca tcaaatgcca cagtgattgg
    13681 tgatgtgaca ttgtcagaag atgtgacgat ctggtatcaa gctgttttac gcggggacag
    13741 taattggata aaaataggac aaagaacgaa tatccaagat ggtacaatca tccatgtcga
    13801 tcatgatgca cctgtagata ttgcggagaa tgtgacggta ggacatcagt gcatgctaca
    13861 tggctgtaca atcgaaaaag gggcgctgat cgggatgggg accacgatat tgaatcatgc
    13921 ggttattggt gagaatagtt tgattggtgc tggatcatta gtaacagaag gaaaagttat
    13981 tcctcctaat gtcttggctt ttggtcgccc agctaaagtg atccgtcctt tgacaaaaga
    14041 agaaatacaa aaaaacaaag aaaacatcca gcattatgtc gagataggtc ggatgcatgc
    14101 gcaaggaaaa ttcaaggagc aaagataggc agtagcatcc ataaaataaa aaaggatggt
    14161 cagtttgagt tgaccatcct tttttatttg gtttagataa gagagcttaa aaaagcttcc
    14221 tttgaaacag attaatttaa tgaagaactg ttttccatga cttcatcgat caatccatat
    14281 gcttttgctt gttcagctgt catatagttg tcacgatctg tatctttttc aatcacttca
    14341 agcggttgtc cagtgcgttc agctaaaatt ttgtttaagc gttcgcgtgt ttgcaaaata
    14401 tggcgtgccg caatttcgat ttcagttgct tgcccttgag cgccgccaag aggttgatgg
    14461 atcatgatct cagcatttgg taaagcaaat cgtttacctt ttgtaccagc tgtcagcaag
    14521 aagcttccca ttgaagcagc catacccata acaattgttt ggacatctgc tttgacaaag
    14581 ttcattgtgt cgtaaatagc catacctgct gtaactgaac caccaggaga attgatataa
    14641 agatagatat ctttttcaga atcttgagcg tctaagaaaa gcaattgggc gatgatcgaa
    14701 ttagcaagat catctgttac ttggccgctt aacatgatga tacggtcttt caataaacgt
    14761 gagtagatat cgtaagctct ttcacctcgt gaagattgtt caatgactgt aggaattaaa
    14821 ttcataatag agttcctcct tgatttcgtt tagaaatagt gtaccataat ttagtttcta
    14881 atacctaaaa tgtagtatac atttttggtc aaaaaaggtc aaataaaaaa cttaggcaaa
    14941 ttagtcgcat aaacccgctt tatggtatga taagcagaga aacaaaacaa ggaggaacaa
    15001 cagattgata gttggtatta ctggccttat cggagtgctg acaggtgctg tagttgtcta
    15061 tatcggcatg atactgcaaa tgcgtcactt ggaaaataaa gaacagcgta gacgtgaatt
    15121 ggaattgaaa gtcaaagaaa tcgagacgct gaatcaatta aataaaaaga tcaacgagat
    15181 cttgcaaaaa cggacaacgc tgatggaaga atatgtcagc tttgatgcat ttgatgattg
    15241 ttatatcacg attgacgatt ttgcgtatct ccaatcattt tcagcgcaaa atagttttta
    15301 tctgccaaat tatattttag acgagctatt taagaatatc tcccatcgaa aagtgatttt
    15361 atctccagat gaaacaatga agattggtgg atatgcttat aaaggcggac gcgtgatttt
    15421 agagaatttt acggatagtc tgactgaaat gatcaatgaa aaaaaagctc agttgaagac
    15481 tatgacgcgc cagccgattg gtttcttctc gaaagatgat gtttggagct gatattttga
    15541 agcattgccg ttgcacatga gagcgtggta atgctttctt tttttcttaa tgatacaata
    15601 gaactgaacg gagtgaagaa agatgttaca aatctatgcc catcgcggaa gcagcggcac
    15661 ccacccagaa aatacgcttc ctgcatttgc agaagctgta cgagtaggtg cagatggtat
    15721 cgaactagat gtccatctaa gcaaagatgg ttatttgatc gttatgcacg acgaagaagt
    15781 ggaccggacg actaacggta aagggctgat tcgagaaaaa acattggaag aactcaaaaa
    15841 attgaatgca gggggcaaat tcagcaaaga atttccagca gctaaagttc ctgaattgag
    15901 agaagtgtta ggactgctcc tccaaaaaaa ttaccgaggg atgctaatga ttgaaattaa
    15961 aactgatcag tatgaatatc ccggtatcga agaaaaatta gccgaaacat taaaaagtag
    16021 agattggcct tttcaacatg catattgcag ctttcatttg gattctttgg aaaaaatcgc
    16081 attactggaa ccggagatac agctggactt attgatgagt acttctgata aaaagatcca
    16141 actagcagca gaaacccctt atatagaagg agtacatcca aaaaatactt ggttgttcga
    16201 acatccagtc caggcagctg attttccaaa agcaattcgt gcatggacga ttaacgatga
    16261 agaagaaatg gccaaatgtc aagaactcaa aatagatgga ataataactg attttccgga
    16321 gaaagctctt cggtggaaac aatcaacgaa aagtaggtaa aatatggaaa aagtattagt
    16381 gatcgtcggt ccgacagcag tcggtaaaac agcgctaagt gtggaactcg cacaactatt
    16441 tggaggagag atcatcagtg gtgattcatt gcaaatctat aaaaatctgg atatcggtac
    16501 agcaaaaatc aaagaagaag agatgaataa tgttccgcat catttgattg atgtgatcga
    16561 acctactcaa cgttactcag ccgctgattt tcagcattca ggtcgacaat tgattaccga
    16621 gattgcgaac cgagggcacc tacctatcat agctggtggt acgggtctct atatccaatc
    16681 ccttctatat gattatcagt taggagcgac agaagaagcg aatcctgaga ttagaaaaaa
    16741 gtatgaaacg ttagctgaaa caattggttc ccaagcatta tggaatcagt tgaaagaaaa
    16801 agacccggca gctgctgaga aaatccactg gaacaatcaa cgcaaagtga taagagctct
    16861 ggaagtttta gagacgacag gacatagtat cacggcacct aaagaagagc caaagcaatt
    16921 gtatgattac ctcatgattg gattagatac gaagcgtagt attctttatg aacgaatcaa
    16981 tcaaagagtc gatttgatgc tagcagaagg tttagtagca gaagcgcgta aggtgtatga
    17041 gcttggagaa gtccaggcca gtcaaggtat tggatataaa gaatttttcc cttattttga
    17101 agggaaagaa acattggaag aagcaacaga acaagtcaaa ctacattcga gaagatacgc
    17161 gaaacgtcag ttgacgtggt ttcgtaaccg tttggatgca cagtggtttg atcttataag
    17221 tgagccaaat caaaaaagtc agattgagca aacaatcaaa aaatggctgg aggcggaata
    17281 aaatggaaga aaaagtgatc atcgtagggg tagaaaccga agcaaaccag cgttactttt
    17341 cagagtcaat ggaagagcta gttcagctga cgaataccgc atcaggagaa gtcgtattca
    17401 caattacaca aaagagacca caagtggatc ggcaaacgat tatcggtaaa gggaaattac
    17461 aagaattagt tcaacaagcg gatgcgcatg aagcggattt gatcatcttt aatcatgagc
    17521 taactccgag acagagccaa ctgattaccg atgctgttgg tcttccggta attgatcgcg
    17581 tgcagcttat cttagatatt tttgcgatgc gtgctcgttc gaaagaaggg aagctgcagg
    17641 ttgaacttgc tcagttagaa tacctgctgc ctcgtttagt agggcaaggg aaaacattat
    17701 ctcgtcttgg cggtgggatc ggaacaagag ggccaggtga aacaaagtta gaaacagacc
    17761 gccgacatat acggaataaa atttttgctg ttaagaaaga attgaaagaa gtagaagctc
    17821 atcgagagcg caatcgccaa aaaagaaaaa atagcgagat ttttcagatt ggacttattg
    17881 gctacacgaa tgccgggaag tcaactatct tgaatctatt gacacaagcg gatacttatt
    17941 cgaaagatca attgtttgca acgttagatc cattgactaa gagatggcgt tttgctgaag
    18001 gatttgagat tactgtaacg gataccgtcg ggttcatcca agacctgcct acgcaactga
    18061 tcgatgcttt ccattctaca ttagaagaaa gtcaaaatat ggatcttttg ctacatgtag
    18121 tcgatgctag ttctccagat cgtattttac aggagcagac tgtcttaaaa ttgatggatg
    18181 aactgaatat gaaagaaatg ccgatactga ctgtttacaa taaggcagac cagatcgacc
    18241 cagcgatgtt cacgcctacg ctattcccaa atgtattgat ttctactcag acgaaagaag
    18301 gtaagatggc gttgatcgaa gcaatcaaac gtcagctgat ggaactaatg accccttata
    18361 cactttctgt gccaagcaac gaaggacaga aattaagcga gttgagaaga caaacaatgg
    18421 ttttggacga agcgtacatg gaagaaacaa acgaatatga agttaaaggg tttgcaaaaa
    18481 ccaattcaaa atggttaaga aaaaaccaat aaaattttat ttttttaa
//
LOCUS       DAZUJR010000059        18408 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.059, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000059 DAZUJR010000000
VERSION     DAZUJR010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18408
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.059"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(17..1783)
                     /locus_tag="ACG804_001950"
     CDS             complement(17..1783)
                     /locus_tag="ACG804_001950"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4832875.1"
                     /translation="MQMIGGLTMKSFYKNKFALTNQGAEDLVKASISSFFVYCINMVP
                     AFIIMMLIDELVLENVKPPWLYFTVSFVTLLFMYWLLDREYENLYNSTYKESAHLRMQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKIVDQGTHSELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(1743..3497)
                     /locus_tag="ACG804_001951"
     CDS             complement(1743..3497)
                     /locus_tag="ACG804_001951"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4832876.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLK
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(3607..4176)
                     /locus_tag="ACG804_001952"
     CDS             complement(3607..4176)
                     /locus_tag="ACG804_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HFS4832877.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(4194..5609)
                     /locus_tag="ACG804_001953"
     CDS             complement(4194..5609)
                     /locus_tag="ACG804_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4832878.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            complement(5620..6288)
                     /locus_tag="ACG804_001954"
     CDS             complement(5620..6288)
                     /locus_tag="ACG804_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T"
                     /protein_id="HFS4832879.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFGTSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(6419..7003)
                     /locus_tag="ACG804_001955"
     CDS             complement(6419..7003)
                     /locus_tag="ACG804_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFS4832880.1"
                     /translation="MESGLSHFEKVGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLV
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(7338..7568)
                     /locus_tag="ACG804_001956"
     CDS             complement(7338..7568)
                     /locus_tag="ACG804_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010708749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HFS4832881.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLTKLRYEDYLDIGFQLTDKGKKFIDDYKKRF"
     gene            complement(7583..8533)
                     /locus_tag="ACG804_001957"
     CDS             complement(7583..8533)
                     /locus_tag="ACG804_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein"
                     /protein_id="HFS4832882.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSTNSKDKDTVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(8530..9372)
                     /locus_tag="ACG804_001958"
     CDS             complement(8530..9372)
                     /locus_tag="ACG804_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HFS4832883.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVTVVLFFKELLIT
                     SFDPLMAKAMGMNVSFYHYLLMILLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGACSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERKL"
     gene            complement(9505..10230)
                     /locus_tag="ACG804_001959"
     CDS             complement(9505..10230)
                     /locus_tag="ACG804_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFS4832884.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKELKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGGTA"
     gene            complement(10691..11005)
                     /locus_tag="ACG804_001960"
     CDS             complement(10691..11005)
                     /locus_tag="ACG804_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFS4832885.1"
                     /translation="MHKDLLIICETGISASLLVSKMLETIRAKNLSYEIDYATIRNVE
                     EKLNYKDYDVLLLTPQVARSEEKVKEIIKKEKCTAQIVYIKQEDFRYMNIENIIASIE
                     ED"
     gene            complement(11021..12616)
                     /locus_tag="ACG804_001961"
     CDS             complement(11021..12616)
                     /locus_tag="ACG804_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute:sodium symporter family transporter"
                     /protein_id="HFS4832886.1"
                     /translation="MNLFSIISFLVIVICVWLFAYSRSRSVDTSGSEGFFMGGRSLTA
                     LPIAGTIIMTNLSTEQIVGQNGQSYHAGMEVMAWEVTATIAIVALAVIFLPKYFKYGI
                     NTISDFIEIRYDTVTKRIISILFIVTYMTSFLPVVLYSGSLVFNKIFHIDELLGVQPI
                     VAIIIVAMAIGIVGILYLLIGGLSLSANSDSIYGVGLLACGLLVPILGLMKLGDGSFV
                     GGIEHVVVNTPWLLNSVGSIDSAVVPWPTLFTGMLFNNLYFWCTNQMIVQKALSGKNL
                     AEAQKGAFLVGVFKILGALFLVFPGIVARNIFGDSLMSNPDNAYPFLVSEVLPKMIFG
                     IFAAVIFGAILSSFAGALNATSTLFSLDFYKPLINKKANDKQIARAGKTVTVVVGIIS
                     IIVAPFISFAPAGLYQFVQEFNGLYNMPLLVIILFAFYSKKATAFGAKTTIAVHIVLY
                     ALSKMLFQNIHFLYVLTALFVLDIIILMVVSKLKPDGEFVLNSFDTKVDIEPWKYTKV
                     TAIALVVIVILTYVAFSPIGFAG"
     gene            complement(12639..13529)
                     /gene="iolE"
                     /locus_tag="ACG804_001962"
     CDS             complement(12639..13529)
                     /gene="iolE"
                     /locus_tag="ACG804_001962"
                     /EC_number="4.2.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010777829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050114 - myo-inosose-2 dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0019310 - inositol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="myo-inosose-2 dehydratase"
                     /protein_id="HFS4832887.1"
                     /translation="MTKQIQLAIAPIAWTNDDMPELGSENTFEQCISEMALAGFTGTE
                     IGNKYPKDPEVLEQYLNIRGLKVASAWFSAFLTTKPFEETAEAFKAHRDFLHAMGAKV
                     IVVAEQGHSIQGIMTAPVFDDKPVFTDEEWKKLAEGLEKLGDLAHEKDMEIVYHHHMG
                     TGVQTTEEIDRLMEMTDPDKVKLLFDTGHLVFSGENPIAVYNRHQDRIKHIHFKDIRQ
                     ETAEEVEKEKDSFLNGVKKGVFTVPGDGMIDFTPIWTAIHASDYEGWIVVEAEQDPAK
                     ANPFEYAVKARSYIREVTGL"
     gene            complement(13546..14571)
                     /gene="iolG"
                     /locus_tag="ACG804_001963"
     CDS             complement(13546..14571)
                     /gene="iolG"
                     /locus_tag="ACG804_001963"
                     /EC_number="1.1.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050112 - inositol 2-dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_process: GO:0019310 - inositol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="inositol 2-dehydrogenase"
                     /protein_id="HFS4832888.1"
                     /translation="MNNIRVGIVGLGRLGKVHAQNLATGVSCCELTAACSLVETELAF
                     AQKKLGVKHTFSSYEEMVKSSVIDAVFIVSPSGFHCDQVRLAMENGKHVFTEKPLGLE
                     VEDIKKTQKVIEEHPEQVFMLGFMRRYDESYQYAKKMVEDGEIGEITLIRCYGIDPSE
                     GLESFVKFAMNNDSGGLFLDMAIHDIDLVRWFTGQEVDQVWAIGKNAAYPELDQAGEL
                     ETGAAMMSLSDKTIALLVAGRNAAHGYHVETEIMGTKGMLRVAQAPEKNLVTIMNDQG
                     IIRPCSQNFPERFREAFIREAQEFVSCIQEKRQPAVNAEDGLQSTKIALACQESFDTK
                     SLVQLKK"
     gene            complement(14595..15602)
                     /locus_tag="ACG804_001964"
     CDS             complement(14595..15602)
                     /locus_tag="ACG804_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFS4832889.1"
                     /translation="MRVKVGVIGTGAIGIEHIDRINQKTQGAYVTAVSDINVKAAKEV
                     AKRVDAKFFETGEALIASEDVDVVVVTSWDPTHEQYVLEAIKHGKYVFCEKPLAMDAA
                     GCRRIVDAEVAYGKKLVQVGFMRRYDRGYIELKEAIESKQYGEALMMHCAHRNPSADE
                     NYTTPMAISNTAIHEIDVLRWLLNEDYESVQMILPKKTSNSHADLHDPQLLIFQTKSG
                     VTIDLEIFVNCRFGYDIKCDVVFETAEVGMTDPAYTRIKSEEKNYTPVSPDWQTRFLD
                     AYDYEFKLWIDSIKNDAVVGPTAWDGYVAAITMMACHESRETKTKVMIQMDERPALYN
                     E"
     gene            complement(15715..16857)
                     /locus_tag="ACG804_001965"
     CDS             complement(15715..16857)
                     /locus_tag="ACG804_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HFS4832890.1"
                     /translation="MPANLRIGGGTIQFLMEESEQLGNKPLIISDTVMEQTGHLQKIK
                     ELLGKTDDQLAEYTDIQAEPTQENVYDALKLFQKHQCDHIIAFGGGSCLDTAKVVAVL
                     AANQLSLEAIHARNFDQLQAGIPLIAVSTTAGTGSEVTDVAVITNTKTAVKMMMKDLV
                     FMPQISIVDSDFTKTVPPKVTAATGVDALCHALESYVSVKANEVTQLFSLEAMKKILN
                     TLSQAYENSDDTEAREQMSLASTEAGIAFSNASVTLIHGMSRPVGALFHIPHGISNAM
                     LLPVFFEFSKDAIQTELATIARFIYPAAEDLSLEEAADYLIKKIQELCEQLSIPTIRD
                     YGIDQQAFMAALDKMAADALTSGSPQNNKKVPSHSQIKELYVQAYG"
     gene            complement(16951..18405)
                     /locus_tag="ACG804_001966"
     CDS             complement(16951..18405)
                     /locus_tag="ACG804_001966"
                     /EC_number="1.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018478 - malonate-semialdehyde
                     dehydrogenase (acetylating) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-acylating methylmalonate-semialdehyde
                     dehydrogenase"
                     /protein_id="HFS4832891.1"
                     /translation="MTRFLRNYIDGRWVASRSTEFEEVMNPATEEALANVPLSSKAET
                     AEAVKAADAAFQTWKKVPVPVRGRYLFKLHQLLTDHKSELARLITLENGKSLSESLGE
                     VQRGIENVEHAAGITNLMMGDSLSTAATDIEITNYRYPIGVIGGITPFNFPMMVPFWI
                     FPMALAAGNTVVLKPSEKTPLLMEKIVELVEKAGFPSGVFNVVYGAHDVVNTLLQDPL
                     VKGISFVGSKNVGEYVYREGTKNLKRVQALTGAKNHVVVLKDANIDRAVKDLIGGAFG
                     SAGERCMAASVIVLEEEIADQFVEKFKAAAKAIKIGNGLDEGVFLGPVIRKDAQQRTF
                     DYIQKGVDEGAKLVLDGRENIPEKGYFVGPTIFDNVTMDMKIWQDEIFAPVASIVRVK
                     DLMAAVELTNESEFANGSCLYTNNASAIRYFRENVDAGMLGVNLGVPAPMAWFAFSGW
                     KHSFFGDLHANGKDSVEFYTHRKVVTARYAQSEI"
BASE COUNT         5671 a         3841 c         2870 g         6026 t
ORIGIN      
        1 tttaaagcct atttcatcat cgtgattgag cttctttttc atagacgaat ttctcagata
       61 gtttagtttt ctttatgaga tttttgtata tttctgacct tcgatacaac tcactatgag
      121 taccttgatc aactattttt ccttgatcca tcactacaat tttatttacc ttttcaatag
      181 acttcaagcg atgcgatata attagtactg tcttatcttg tattaaacga tttaaacttt
      241 cctgaatacg tttttcattt tccgcatcta aactggcagt aatttcatct aaaattaaaa
      301 ttggcgcatt tttcaaaaaa gcccgtgcta tggataggcg ttgtcgctct cctccagaaa
      361 gtgaacttcc gttttctccg accaatgtat gataaccgtc aggtagtttt tcaataaagt
      421 cttcgcagtt agctaaacga gctgcttttt tcacttcctc atctgacgct tgactatttc
      481 caatacgtat attttccaaa atacttgtat taaacaaagt tacctcttga aaaacaatag
      541 cgattttgct aaacaaagaa gctggagata cacgtttaat atcataccca tcaattaaaa
      601 tacagccttc atcataatca tacagtctag acactaattt caagatacta gttttcccgg
      661 aaccactagc acctactaac gcagtcactt ctccttgttt agccgtaaaa gagatatgat
      721 ctaaaattgg ggtattgtta tcatatgaga aagagacatc tcgcaactca atgtcaaaag
      781 atttcagagg actatctgat ccctcttgga tactggtttc cttcatagct ctaattcgct
      841 gtattttagg agctaaataa aatatttcaa gcactgcttc tttcatagaa tcgaaggaat
      901 cctttatttt tattgcggct agtaagtaac caacgacgta gagtatagtc acttcacccg
      961 ttaacagtaa gtgaacacct actagaatga ctactgctaa actaacatat gagaaaatag
     1021 aggataaggc catgactgaa aaagtactta attctacctt taaatgaatc ctttcactct
     1081 cttccatttt tttgaaaagt ctgtcttgaa cttttttaga tagattaaag ctattaatct
     1141 cttgctgcaa ttctatagtt tcttgaaatt cttccgagtt ttctctcaaa gtatcgtaat
     1201 atttagtatt ggctttcgtt tgggatttct ttgataacaa gattaagaca aaactaaata
     1261 acgttggcaa aataacagct aatcccattt tgacattacc aaccaaaagc atcactgaaa
     1321 taaaagggaa aaacagagcc ataccgccgg ctttaggtat tgcatgactc atcgcatgct
     1381 caataccttc aacgtcagac atgatagttt gagataaatc tgataaatta tgttttgaaa
     1441 aataggataa tggtaaattt gacaaatcgt ctgcaatttg cattcttaaa tgcgcacttt
     1501 ctttataagt actattatat aagttttcat actccctatc taacaaccaa tacatgaaaa
     1561 gcaaagtaac gaacgatact gtaaaataaa gccaaggcgg ctttacattt tctaaaacta
     1621 attcgtctat cagcatcatt ataatgaatg ctggtaccat attaatgcag tatacaaaaa
     1681 agctagaaat agatgcttta accaaatctt ctgcgccctg attagttaaa gcgaatttgt
     1741 ttttataaaa acttttcatt gtcaagcctc caatcatttg cattctcata attagtgacc
     1801 aattgtttat acacttgatg tttagccatt aattcattat gatttccacg ttctactatt
     1861 ttcccttctg acaagacaag aatttcatct acagatttaa tgctggataa tcgatgagct
     1921 atcataataa ctgttttttc tttcatcaga tgttgaaaag ccttttgtag ttcatactca
     1981 ttatctggat caatagatgc actggcttca tccataataa caatctttgc atcttttaaa
     2041 attgctctgg caatagctat acgttgtttt tctcctcctg acagataaac tcctttacta
     2101 ccaattaagg tatgctctct ttcgggaaat ttttctaaaa tcgattcgca accggctaat
     2161 cttagcgcgt caaatacttt acttgctggc gcttgaggat ttgctataga aacgttatcg
     2221 taaatactct gattgaatag tttcgtatct tgaaagacaa aagcaattgt gttaataatt
     2281 gtgtcttttg aatagtgatt taaaggctta ccaccaattt taatctgtcc cttatccaca
     2341 ttgtagaaac ctgaaattag tttagctatc gtactctttc cgcttcctga ttttcctact
     2401 aatgcataaa ttcttttttg ttctaaaact aagttgaaat tttctaaaac acactcttct
     2461 ttgtatgaaa agctgacatt ttcaaatgca atgtcacaat ttttaatctg tgtctcgttc
     2521 ccatatttta gttggtcttg cttcatttct aaataaaggg agtctagtgt ttcgactgca
     2581 tatcttgctt caaacaagtg catacttaca tacattattc tcatgaaaga aacaaaaata
     2641 attccactta aaaaaaacaa catcaacaag tcaacagcta atatcttggg agtggtaaga
     2701 gaagttataa aaaaggttat aggaactatc aaaatgcaaa ctatgccaaa aaatagccat
     2761 tgaaaaagaa caaaaggtgt tttcccactc aaagaatact tatatgcaaa cttagcataa
     2821 tcgttaattg ctttattcaa ggctttaaat gatgttactt tagcaccaaa tatctttata
     2881 acttgaattc ctcggatata ttctaccgtt tcagagctta acacatctaa cgattcttga
     2941 tatttttgaa taaaatttgt attctctgtc attttcttta acaagaatac accaattact
     3001 aacatggcga ttagaaccaa tccaatttta aaattaatga aaaagcctaa ggcaactgat
     3061 aaaacaggtg ttactatggc ttgagcacta tctggaatca agtgagcaat tgccatatgt
     3121 gttttagccg cgttgtcatc aattgtcttt cgaatatatc ccgaagaatt taaatcaaaa
     3181 aaacgaaaac ttgcttctgt taaaccgcta attccctttt ttctcaaatt agtctctaag
     3241 cgaaacccaa ggatatgaga aaataagcca gaaaaaatat aaaataaagc tcctaaagtt
     3301 aaccaagcaa cagtttgaac cgcataactc ttagctaaat attcatctcc tacaataatt
     3361 agagacttaa gaaatttgta aatactgtaa tatccataga ctgttaatac gacagaaaaa
     3421 tcagaaaata aagtggctaa ccatccgtag tatttcattt tagggacata actaaataat
     3481 tttttgtata ctttcatttt ttcctccccc gcattcaatt tcttctctta ttcgtttaca
     3541 actgttaatg ctttccgtaa tagcgtaaat tagagatgta caaacagata gaaggtaaac
     3601 tacgttctat tttttgtatt tttttaagac ttttcttcca atcaatacac caatcataga
     3661 taaacttgct acaactaaca ctgaaatgat tccccatata cctaccgcat agtggatcat
     3721 tgcatccatt gttgcagcag attgtccttt atctatccaa tcttgacgaa aacgatctgt
     3781 aaagaaccat ataggaatcc actgtccggc agcactgcct aattgcatta gagcccaaga
     3841 cgcaacttga ggaattgctc gatcatatcc aaatacagat agaataatat cagctaagat
     3901 cgccatacta atcgaactga taaaccaagg taagtacgcc ccgcccatta acgtaaaaaa
     3961 taacaataaa acaattgtgt aaatagtaaa aattcctttt ctagggtagt tatagctaat
     4021 ataaacaaat atgattccag ataataatcc aaaaatccct ggggatatgc tgtgaccaaa
     4081 cgccccacca atactactaa ccattattga aaaaaagtaa attactaggg aaataactgt
     4141 agctaaacca ataaaaatat aatcttttgt tttcatatat attctcctca attctatttc
     4201 gttatgtcat taaaaatctg ttctatcaaa gttgaatctt ctactctaag ttttatatct
     4261 ttttttattc caccattttt taaataaata attctattgc atgttttata aagaaattcc
     4321 ggatcatgag tggctataac tactgcaccc ttttctttta agtctttaat aaggtcagca
     4381 atcctttcca tattaatata atccaaccca cttgtaggtt catcaaatag aaataaatta
     4441 gtttttgaca atgaagctat agaaaccaat aatctttgtt tttctccacc ggataaatca
     4501 aacggtaatt gatctttcat tttataaagt tccatttttt ttaaaatttt ttcttgctga
     4561 tctttactaa ctatttcatt ccccagggct aactcgctcc tcactgattc tgtgaaaaat
     4621 tggtaatcca tttcttgcat tactaaaaac ggcgatgaca aatttttttt attttcgatt
     4681 atctttcctt tggtagggcg aataatcttc atgagtattc ttagtaaggt tgttttcccc
     4741 acaccgtttt tccctaccaa accaataaca tctccaactt tgacatcaaa atttatgtct
     4801 tttagaatat tttcataagt aatttcttca acttttaata catctgcact taccttttcg
     4861 atatagggaa cttcaatcga actattaaaa atgtcaaatt tccttaatgc gttattgttt
     4921 tcagttttta acaactgaat agttgtagtt tttacagttc tatttttaac aaatagaact
     4981 tgatcaatta attctttcaa atagtaaaaa cgatgttcag ctataacaat agtaaatcct
     5041 ttatttttta aatcacaaag taagtcagca agtttcttag tcgctttgaa gtccaaattt
     5101 gaagacggtt catccaatat aattaattta gagtttagcg ataaactaca tccaatagaa
     5161 attttctgcc gttcaccact tgatagcgaa aaaatgtttt tatctaatat atttgaaaga
     5221 tctaataatt cagctaattc attgattctt ttatccatat gctcttttgt aaatccaaag
     5281 ttttccatcg aaaatactaa ctcactcgtt gtatttgttg taaagaattg tcctctagga
     5341 tcttgactta cgtagccaat attttttgat atactttctt gtgttaagga ttgtagcgag
     5401 ttattttcaa ataaaatttc cccaaccaat tttccgtcat aaagtcttgg aataagtcca
     5461 ttcattaact ttaatagtgt ggatttccca ctcccagaag aaccagtaat caatgtaaga
     5521 ctaccttttt ttattgaaaa attaaggtca acaagcgctt gttccttaac atccttatat
     5581 gaaaaagaaa cattgttaaa ttcaaacaat tctttcacct caaatcaaaa tacttaagaa
     5641 aaaaatagta acggaaaaca ggatgatata gtctaataag ctcatgtttg ttttatagta
     5701 agaacttctt ttcacaggag attctatccc ctttgttatt gcattagcgg tcatttcttc
     5761 agcaatcata gttgcacgta taagaacggg aactaacaga aattccaaat attgcagagg
     5821 ctgaaaaaaa gacaagcgaa tgtttctcat ttttaaagat tctttaatca ttcttatttc
     5881 agaacgataa gtcggaaaga atctgatcac tactgtaata cttaacatta tttttttcgg
     5941 taaatgtatt ttttctaaag aggataataa ttcattgcta gtatagacac taaccaacaa
     6001 ccatgagatc attacgaccg gcaacattcg aaatacaata tataaggatg tcccaaaaaa
     6061 tatagtaaaa aactctatct tgatagcatc aataattttc attactaaaa acagaactga
     6121 ataaatcaag atgaaataaa tacatgtctt tattttacga aacatcaata ctaaaactgt
     6181 agcaataatg aaacacccca cttgaaatat atttcccttt cctaaaaaaa taatgaccgg
     6241 aaaaaaaata tttaaagtaa tcaaggttaa cggattgatt tttgacactc tttcacctcc
     6301 aaaaaataag atcgcactgt tatcttaagc tgataaaaat gcaccgttat tcagataaca
     6361 gtgcgatctt atcaaaaagc ataactgaga acaattctca atgcaagctt ttttttaatt
     6421 aactcagtaa ttcaatccac ccaggaacag aaaattgata caatcttctg gttaatagca
     6481 tagtcttttc ttttgaatag ctatgcttca atatatcata gaatgtagcg tagaatgagt
     6541 aaatgtagaa gtggatttct tcttcattaa agactaaatt ttgattgatc attccgatag
     6601 tctttaactt atctagacaa cagactgtct tttttgtcac aaatgatgta attttttcaa
     6661 caatatcttg atatttggtt ccagctgatt ggaataaaac caaatcgaat atacgtttat
     6721 tctcaaaaat ataattaata aatggatcta attcattgaa gttctctctc caacttttct
     6781 ctatatctat attttctaag tttaagaggt atttggtaaa ctcttcatta tacatattaa
     6841 taagcgcatt aatatgcggc tgaataattt cttcaaataa cgcttcctta gaagtaaaat
     6901 gtttataaaa agcacccgta gttacgcctg cggtcaagca cagttgcctt atcttagttt
     6961 gctgaaatcc tactttttca aaatggctta gtccactttc tattaatttt tggtgagttg
     7021 taatataatc tctggtttct atgggtactt cctcctaata agatgaatta actatattat
     7081 cttacacagg acttgaagtt tcaatcgtta acgtctatta ctgaactcat tccttagagc
     7141 taaactaatg agaaagagca aaataactga tacaaaaagc aatcctacaa gaattaatag
     7201 actcatctaa atcattcacc ttttctaaaa taatccgaga aagatttaaa aaaattatat
     7261 ccagctatta ggataagtcc tatcataatc actccaatag ccattttctt atcctcccta
     7321 aaaataaagc cttttactta aaaccttttt ttgtaatcgt caataaattt tttcccttta
     7381 tcagttaatt gaaatcctat atctaaatag tcctcatatc taagtttagt cagcatctca
     7441 cttacagatg ctggactaac acttagaact tttgctaaat cattattttt taatttcttt
     7501 tttctttttg ataattcctg aattgctagt aaataaatta gtatagtagt tgttttaatt
     7561 tgtaccatac ctaccctcca aattatttcg aaaggccttc agcaatttta tccaggttcc
     7621 atttcatcat cgcatagtaa ctatcaccat cttgtccttt ttctgcaatt gaatcagtaa
     7681 aaatcgttga atagatagga atattggtat cttttgatac tgttttcatt ggtctatcgt
     7741 ccacactgct ttctacgaat aaggagggaa cttttgttgt gcgtaatttt tcaactaagt
     7801 gttttatttg atctggtgtt ccttcttctt cagtgttgat ttcccaaatg taagcagaag
     7861 gcacattata cgctttcgag aaatatttaa agcatccttc acttgtaaca atcatttttt
     7921 tatcattcgg aattgaagca aatttagatt tagcttcttt gtctagagaa tccaattttt
     7981 caatatactt atctagattt tctttataga attttttatt atcaggatct ttttccgcta
     8041 actgtttttc aatattttta gcgtaaataa taccgttttc taaatttaac caagcatggg
     8101 gatcttcctt ccctttctca ctctgaccct ctaagtaaat aacatctatg ccatcacttg
     8161 ctgcaaaata gtctttgttt tcctctttgt tcgcattttt tactaatttt gtaaaccaag
     8221 catttcctcc agtttccaag ttaacaccgt tataaaaaat caaatctgct tttgaagttt
     8281 tttgaacatc ttcaggcaaa ggttcatatt cgtggggatc tttcccaata ggtacgatac
     8341 tgtgtaaatc aattttatct tttgctatat tttcagtaat atctgctaaa atcgaattag
     8401 taactactac ctttaatttt tcgttcgaag ccactgtatc tttgtcttta ctatttgttg
     8461 aacatgcccc gaatataaaa agagcaatca aaatccccag acttcccagt actgctttcc
     8521 attttctcat cataactttc tctccttctt tcttaaaaat ttttgttttg gtgagattag
     8581 aaaactaatt acaaataaga atgccgctgt taaaacaata cttgatcctg ctgctatgtt
     8641 aaaactataa ccaatgaaca aacctagcaa tgatgagcac gctccgactg tcgccgaaat
     8701 aaatatcata gtttttaaac tgtttgcata taaatatgct gtagcagctg gtgtaattaa
     8761 cattgcaaca attaatatag ttcccacact ttgcatagct gttactgcta ctaaagttaa
     8821 tagaatcatt aatagataat gataaaaact gacattcatc cccattgctt ttgccattaa
     8881 tggatcaaaa gaagtgatta ataattcttt aaaaaataga acaactgtaa ccaacactaa
     8941 aacagaaacg ccaattgtaa tccacttatc aatatcttgt acagctaaaa tatttccaaa
     9001 taagatatga aataaatccg ttgagctatt tgcaactcct ataaggataa ctcctaatgc
     9061 taaaaaagaa ctgaaagtaa taccaattgc tgtatctcct tttattacac tattgctttt
     9121 tataaaagta ataatgatag aagctaatag accaaataca atcgcaccaa taaaaaaatt
     9181 aatacctaaa atataagaaa ttgctactcc tggcaaaaca gcatgagaaa tagcatcacc
     9241 cataagagac attcctctta aaataataaa acaacctact gttccagaaa caatccctat
     9301 aactacagat gtaattagag cattctgtaa aaagtgaaag tcatacagac cattaataaa
     9361 attttgaagc atattattcc ccttgtatat tagagttagg gttttaacct tccggttttg
     9421 attggataac cctatgaacc atcgttattt taatttggta ttaactcatt tcttttgaga
     9481 taatatattt attggattga gaggctaagc cgttcccccc tctccaataa atatagtatc
     9541 tccataggct ttttttaaat tctcttcatt aaatacagat tctacacttc cgtgagcaat
     9601 tagatttcga ttcaaaagaa taatattatc aaaatacttc tttaccttgc ttaaatcatg
     9661 atgcacaatt agcactgttt ttccctgatg tttcaattct tttaacgtat ccataattat
     9721 tcgttcacta actaagtcta tccctacaaa tggttcatct aaaaatatga aatccgcatt
     9781 ttgagcaaga catcttgcta aaagtacacg ttgaaattgt cctccagata attctcctat
     9841 ttgatgatta gaatattttc ccatatcgac cttttccaaa gcctttgaaa ctctttgcca
     9901 ttctgcattt ttaattcttt gaaaaacttt cattccggca tatgttccca tagatacaca
     9961 ttcttttact tttattggaa aagtaaaatc aatatcagct ttttgctcta catatgcaat
    10021 cttcaccagt tttttattga tatcttcatt attaatggag acctctccct gatgagggat
    10081 aatatttaac attgctttaa gcaatgtaga ttttccagca ccatttggac caataatacc
    10141 tgttaaagca ccttcttgta tttttaaaga aatctcgttc aatgctaaaa aatcgttata
    10201 acaaacatta agctttttca cttctaacat aactttctcc ttctaaatga taatgattat
    10261 cacgatcata tggtatacaa aaattatatt ttagtcaacc ctaaatttta taatttagat
    10321 ttttttctgt tgttgaagat taggatgtca aaattatttg aaactactcg tatagtaaat
    10381 agtaagtaat tttcaaaaca cgaagaaaaa caaaaagaaa aaaggaaacg ccgaagcatt
    10441 tcctttcagt gatttaatga gaacaacacg atttgactta gagtctcaaa aagtcgaata
    10501 ggtacactca tttaagtgtc tccattcgac tttttgggga tgagctggct attgaggtcc
    10561 gcttacccta ttgaataaat acaagattgg gtatttctaa taagtccgcc cttcatattg
    10621 gggtgatcgg ggcgaacatg ccatcttttc atataccacc tcctcgacac tcaataatca
    10681 aagattctcg ttaatcttct tcgatgcttg caatgatgtt ttcaatattc atataacgaa
    10741 aatcttcttg tttgatataa acgatctgag cggtacattt ttcctttttg atgatttctt
    10801 ttactttttc ctcagaacgt gcgacctgcg gcgttaaaag taaaacgtca tagtctttat
    10861 aattcagttt ttcttcaacg tttcggatcg ttgcataatc tatctcatac gatagatttt
    10921 tggctctgat cgtttcaagc atttttgata cgagcagcga cgcactgatt ccggtctcgc
    10981 aaataatcaa tagatcctta tgcataatac cctcctgttt ttagcctgca aagccaattg
    11041 gtgaaaatgc cacataagtt aaaataacaa tgactaccaa tgctatagca gtcaccttgg
    11101 tgtatttcca aggctcgata tcgacctttg tatcgaatga gttcaacaca aattctccat
    11161 caggtttcaa tttggaaacc accatcaaaa tgataatgtc cagaacgaat aatgccgtca
    11221 aaacataaag gaaatggata ttttggaaaa gcatttttga tagtgcatac aagacgatat
    11281 gcacggcaat cgtcgttttt gccccaaaag cagttgcttt ttttgaataa aaggcaaaga
    11341 gaatgatcac gagcagcggc atgttgtata gtccattgaa ttcttgaacg aactgataca
    11401 atccagccgg tgcaaaagaa atgaatggcg ctacgataat ggagataatc cccacaacga
    11461 ccgttactgt tttaccagca cgagcgattt gcttatcatt tgctttctta ttgataagcg
    11521 gtttataaaa atccagtgaa aacaaggtcg atgtcgcgtt caaagctccc gcaaatgatg
    11581 ataagatcgc gccaaagata acagcggcga aaataccaaa gatcatttta ggcaatactt
    11641 cactgactaa aaaaggatac gcgttatctg gatttgacat taaactatcg ccaaaaatat
    11701 tgcgagcgac gatccctgga aagacaagga ataacgcacc taagattttg aagacgccga
    11761 ctaggaaagc gcccttttgt gcctcagcta aattcttgcc ggacaatgct ttttggacga
    11821 tcatttgatt ggtacaccag aaatacagat tgttaaacag catccctgta aatagtgtcg
    11881 gccatggaac aacagccgag tcgatcgatc ccacagagtt aagcagccat ggcgtgttta
    11941 ccacaacgtg ttcgatcccg ccaacaaagc tgccgtcacc aagcttcatt aagcctaaaa
    12001 ttgggaccag cagaccacaa gccagcagac cgactccata aatggagtca ctattggcac
    12061 ttaacgacaa gccgccgatc agcagataga ggatgccgac aataccaatt gccatcgcta
    12121 caattatgat cgcgacgatc ggctggacgc ccagcagctc atcaatatgg aagatcttat
    12181 tgaacaccag cgatccagaa taaagaacca cgggtaagaa agaagtcata taggtcacaa
    12241 taaataagat cgaaataatt cgtttggtaa ccgtatcata acgaatctcg atgaaatctg
    12301 agattgtatt gatgccgtat ttaaaatatt ttggcaagaa tatcacagcc aaagctacga
    12361 tcgcaatcgt agcagttact tcccaggcca ttacttccat ccctgcatga taactttgac
    12421 cattttgtcc gactatttgt tcggtggaca ggttcgtcat gatgatcgtg ccggcgattg
    12481 gcaaagcagt taagctccgc cctcccatga agaacccttc tgatccagaa gtatcgacac
    12541 ttctggatct agaataggca aataaccata cacagatgac aatcactagg aaactgatta
    12601 tagaaaaaag attcatcgtc tagctccttt tcaatagatt aaagaccggt gacctctcga
    12661 atgtagcttc tggctttgac tgcatattca aatggattgg ctttagccgg gtcctgttct
    12721 gcttcaacta cgatccagcc ttcatagtcg ctggcatgga ttgctgtcca gattggagtg
    12781 aaatcaatca tcccatcacc aggaaccgtg aagacgcctt tcttcacgcc gtttaagaag
    12841 ctgtcttttt ccttttctac ttcttcagcc gtttcttgac gaatatcttt gaaatggatg
    12901 tgtttgatac gatcttgatg acggttgtaa accgcgattg gattttcacc agaaaagacc
    12961 aaatgtcccg tatcgaacaa taatttaact ttgtctggat cagtcatttc cattaaacga
    13021 tcgatttctt ccgtcgtttg aacgccggta cccatgtgat gatggtaaac gatctccata
    13081 tccttttcgt gggccaaatc ccctaatttt tctaatcctt ccgccagttt tttccactct
    13141 tcatcagtga aaactggttt atcatcaaag actggcgctg tcataatccc ttggatacta
    13201 tgaccctgct cagctactac gatgacttta gcgcccatcg catgtaagaa atcccgatgt
    13261 gctttgaagg cttcggcagt ttcttcaaaa ggtttagttg tcagaaacgc actgaaccat
    13321 gcactggcaa cctttaagcc gcgaatattc aaatattgtt ccaacacctc tggatctttt
    13381 ggatatttgt tgccaatctc tgttccggtg aacccagcaa gggccatttc actgatacat
    13441 tgttcaaagg tattttcact accaagctcg ggcatatcat cattggtcca cgcgattggt
    13501 gcgatggcta attgaatttg tttggtcata ttctcacact cctgcttatt tttttagttg
    13561 tactaaactc ttcgtatcga atgattcttg acaagccaac gcgatcttag ttgattgcaa
    13621 tccatcttct gcattaaccg ctggttgacg tttttcttga atacatgaga caaattcttg
    13681 ggcttcacga atgaaggctt ctctgaatcg ttctgggaag ttttgtgaac atggacggat
    13741 gatcccttga tcgttcatga tcgtcacaag atttttctca ggcgcttgcg ctacccgcag
    13801 cattcctttg gttcccatga tctctgtttc gacatgatag ccatgggctg cgtttctgcc
    13861 ggcaactagt aaagctattg ttttatcgct caggctcatc attgcggctc cagtttcaag
    13921 ctcaccagcc tgatccaatt ctggatacgc cgcatttttc ccaatcgccc acacttgatc
    13981 gacttcttgg ccggtaaacc agcgaaccaa atcaatatca tggatcgcca tatctaagaa
    14041 caagccgccg ctgtcgttat tcatggcaaa tttgacaaag ctttccaagc cttcgctcgg
    14101 atcgatccca taacaacgaa tcagtgtgat ttcgccgatt tcgccatctt ctaccatttt
    14161 cttcgcatac tgatacgact catcatagcg gcgcatgaag cctaacatga agacctgttc
    14221 aggatgctct tcgatgactt tttgggtctt tttaatatct tcaacttcaa ggcctaatgg
    14281 tttttcagta aagacatgct tgccattttc catcgccaag cggacttggt cacagtgaaa
    14341 gcctgatggt gaaacaataa agactgcatc gatcacggaa cttttgacca tttcttcata
    14401 gctggaaaaa gtatgcttga cgcctaattt cttctgtgcg aatgctaatt ctgtttcaac
    14461 taaactgcac gcagccgtaa gctcacaaca actgacacct gttgctaaat tttgtgcatg
    14521 tacttttcct aatcttccta aaccgacgat gcctactcta atgttgttca tgaaatacct
    14581 ccgttttctg agaattactc attgtatagt gctggtcgtt catccatttg aatcattact
    14641 tttgtttttg tttcacgaga ctcatgacaa gccatcatgg tgatcgctgc tacataccca
    14701 tcccaagcgg taggaccgac aaccgcatca tttttgatcg aatcgatcca cagcttgaat
    14761 tcataatcat aggcatccaa aaagcgggtc tgccaatctg gtgaaacagg tgtgtaattt
    14821 ttttcttccg atttaattcg tgtataggct gggtccgtca ttcctacttc tgccgtttcg
    14881 aaaaccacat cacatttaat atcgtagcca aagcggcaat tcacaaagat ttccaaatca
    14941 atcgttacac cggattttgt ttgaaagatc agcagctgcg gatcatgcaa atcggcatgg
    15001 gagttgctgg tttttttcgg caagatcatt tgaacagatt cataatcttc atttagcaac
    15061 cagcgaagca catcaatctc atgaatcgcg gtgttgctga tcgccatcgg tgttgtgtag
    15121 ttttcatctg cgctaggatt tctatgggca caatgcatca ttaatgcttc tccgtattgc
    15181 ttcgattcga ttgcttcttt cagttcaatg tagccgcggt catagcggcg catgaagcca
    15241 acctgaacca atttcttccc ataagcaact tccgcatcaa cgatccggcg gcagcctgct
    15301 gcatccatcg ctaatggctt ttcgcagaaa acatatttcc catgcttgat tgcttctaac
    15361 acatactgct catgggtcgg gtcccaagaa gtcacaacaa cgacatccac atcttcagaa
    15421 gcgatcaatg cttctccggt ttcaaagaat ttagcatcga cacgtttggc aacctcttta
    15481 gcagctttta cattgatatc tgagactgct gtcacataag ccccttgtgt tttctgattg
    15541 atcctgtcga tatgctcgat gccgattgca cctgttccga taacgcctac ttttactctc
    15601 aattacttat ccccctgttc tgttgtttaa gcacacatag tatgcgctta caaaattatt
    15661 cctgtgtagc ttttattctt aaaaggtaga gccctctctt tgctccgcct tttactaccc
    15721 ataagcttgt acgtataatt ccttaatttg actatgacta ggcacctttt tattattttg
    15781 cggacttccg ctggtcaacg catccgcggc cattttgtct aaggctgcca taaacgcttg
    15841 ctgatcaata ccataatctc gaatcgttgg gatcgacagc tgctcacaga gctcttggat
    15901 ttttttaatc agataatccg cagcctcttc cagcgataaa tcttcggctg ccggataaat
    15961 aaatctggcg atcgtcgcta actcagtctg aatagcatcc tttgagaatt caaaaaagac
    16021 cggcaataac atcgcatttg atatcccatg aggaatgtga aaaagtgccc ccaccggtcg
    16081 actcattcca tgaatcaatg tgactgacgc attcgaaaag gcaatccccg cctccgttga
    16141 agctaagctc atttgttctc tggcttcagt gtcgtcgcta ttttcatatg cctgagaaag
    16201 cgtgttcaaa attttcttca tcgcttccag tgaaaatagt tgcgttactt cattggcttt
    16261 gactgaaaca taagattcca aagcgtgaca tagcgcatcg actcccgttg ccgcggttac
    16321 ttttggtggt acagttttcg taaaatcaga gtcaacgatt gagatctgtg gcatgaaaac
    16381 gagatccttc atcatcattt tgactgctgt ttttgtattg gtaataactg ccacatcggt
    16441 tacttccgaa ccagttccag cagttgttga cactgcaatc agcggaatgc ccgcttgcag
    16501 ctgatcaaaa tttcttgcat gaatcgcttc gagacttaat tgattagcag ccaaaacggc
    16561 taccaccttg gctgtatcca gacagctgcc gccaccaaaa gcaatgatat gatcacattg
    16621 atgcttctga aaaagcttca gcgcatcata aacattttct tgcgtcggtt cggcttgaat
    16681 gtctgtatac tccgctaatt gatcatctgt ttttcccaac agctccttga tcttttgaag
    16741 atgcccggtc tgttccataa ccgtatcact aatgattaac ggcttgttgc ctagttgttc
    16801 tgattcttcc ataagaaatt ggattgttcc gccgccaatt cttaaattgg caggcatttt
    16861 cagttgaata ttcacagaaa aaacctctct ctggcttata gcctataaca gaatcctcga
    16921 agctctttaa cagagcttcg aagcaaatct ttaaatctca ctttgcgcat aacgtgctgt
    16981 aacaactttc cgatgggtat aaaactcaac actgtctttg ccattggcat gcaaatcacc
    17041 aaagaaagag tgcttccagc ctgaaaaggc aaaccaagcc atcggtgcag gcaccccaag
    17101 attgaccccc agcatcccag catcaacatt ttctctgaag tagcgaatcg ctgatgcgtt
    17161 gttggtatac agacacgaac cattcgcaaa ttcagattca ttcgtcagct caacggctgc
    17221 catcaaatct tttacccgca cgattgatgc gaccggggca aaaatctcat cctgccagat
    17281 cttcatatcc atcgtgacat tatcaaaaat cgttggtcca acaaaatagc ctttttctgg
    17341 aatgttttcg cgaccatcta gtaccagttt cgctccttca tcgacccctt tttggatata
    17401 gtcaaaggtc cgctgctgtg catcttttcg aatcactggt cctaaaaaga ccccttcgtc
    17461 caagccattg ccgatcttga tcgcttttgc cgcagcctta aatttttcaa caaactgatc
    17521 cgcgatttcc tcttccaaaa caatgacgga ggctgccatg cagcgttcac cagcagaacc
    17581 aaaagctccg ccaataaggt ccttgactgc ccgatcaata ttggcatctt tcagcacaac
    17641 aacatgattt ttcgctccag tcaacgcttg tacccgtttt agattttttg ttccttcacg
    17701 gtaaacgtat tcaccgacat tttttgatcc tacaaagctg atgcctttta ccagtggatc
    17761 ttgcagcaat gtgttgacaa catcgtgggc accatagaca acattaaaaa caccgctagg
    17821 aaagcctgct ttttcaacca gctcaacaat tttctccatc aacaatggtg ttttttctga
    17881 aggcttcagc accaccgtat ttcctgccgc cagagccatc gggaagatcc agaagggcac
    17941 catcattgga aaattaaacg gtgtgatccc tccgattact ccgattgggt aacgataatt
    18001 cgtgatctca atatcagtcg ccgctgttga taaagaatct cccatcatta aattggtgat
    18061 tcccgctgcg tgctccacat tttcgattcc tcgttgaact tctcccagtg actcggacaa
    18121 tgatttccca ttttccagcg tgatcaaacg cgccaattca cttttatgat ctgttaaaag
    18181 ctgatgcagc ttgaacagat aacgtccgcg aacaggaaca ggaacttttt tccaagtttg
    18241 aaacgcagca tcggcagctt taactgcttc ggctgtctct gctttgctag acaacggtac
    18301 attcgccagc gcttcttctg tagccggatt cattacttct tcaaactctg ttgagcgact
    18361 agcgacccaa cgaccatcaa tataatttct taaaaatctt gtcattta
//
LOCUS       DAZUJR010000060        18146 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.060, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000060 DAZUJR010000000
VERSION     DAZUJR010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18146
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.060"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(50..1558)
                     /locus_tag="ACG804_001967"
     CDS             complement(50..1558)
                     /locus_tag="ACG804_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HFS4832892.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            1717..1908
                     /locus_tag="ACG804_001968"
     CDS             1717..1908
                     /locus_tag="ACG804_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832893.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            2111..3028
                     /locus_tag="ACG804_001969"
     CDS             2111..3028
                     /locus_tag="ACG804_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coiled-coil domain-containing protein"
                     /protein_id="HFS4832894.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            3021..4094
                     /locus_tag="ACG804_001970"
     CDS             3021..4094
                     /locus_tag="ACG804_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832895.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            4242..4760
                     /locus_tag="ACG804_001971"
     CDS             4242..4760
                     /locus_tag="ACG804_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832896.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            4741..5133
                     /locus_tag="ACG804_001972"
     CDS             4741..5133
                     /locus_tag="ACG804_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HFS4832897.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            5209..6144
                     /locus_tag="ACG804_001973"
     CDS             5209..6144
                     /locus_tag="ACG804_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFS4832898.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            6277..7056
                     /locus_tag="ACG804_001974"
     CDS             6277..7056
                     /locus_tag="ACG804_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HFS4832899.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            7049..7366
                     /locus_tag="ACG804_001975"
     CDS             7049..7366
                     /locus_tag="ACG804_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HFS4832900.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            7610..9220
                     /locus_tag="ACG804_001976"
     CDS             7610..9220
                     /locus_tag="ACG804_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFS4832901.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            9377..10225
                     /locus_tag="ACG804_001977"
     CDS             9377..10225
                     /locus_tag="ACG804_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFS4832902.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            10456..10935
                     /locus_tag="ACG804_001978"
     CDS             10456..10935
                     /locus_tag="ACG804_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6530 family protein"
                     /protein_id="HFS4832903.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            10968..13196
                     /locus_tag="ACG804_001979"
     CDS             10968..13196
                     /locus_tag="ACG804_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFS4832904.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            13325..14968
                     /locus_tag="ACG804_001980"
     CDS             13325..14968
                     /locus_tag="ACG804_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFS4832905.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(15041..15586)
                     /locus_tag="ACG804_001981"
     CDS             complement(15041..15586)
                     /locus_tag="ACG804_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HFS4832906.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(15609..16094)
                     /locus_tag="ACG804_001982"
     CDS             complement(15609..16094)
                     /locus_tag="ACG804_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFS4832907.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(16084..16896)
                     /locus_tag="ACG804_001983"
     CDS             complement(16084..16896)
                     /locus_tag="ACG804_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HFS4832908.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(17035..>18146)
                     /locus_tag="ACG804_001984"
     CDS             complement(17035..>18146)
                     /locus_tag="ACG804_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HFS4832909.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT         5894 a         3303 c         3631 g         5318 t
ORIGIN      
        1 atcgattaag ctaatagttt cgttttcaac atttataagt aaactttttc tattggtaat
       61 atagattttc ggaagggtag acaggtgcgc aggtaatatc gattcctagt tttttcaatg
      121 tttgttcatc atttttattg accatcacag tagagtgggc ttgtgctccc tcaagttcag
      181 ctagtttatc ataagcaact tgagcgattg gattcgttac tgcactgatt gataaagcga
      241 tcaagacttc attgatgctt agtgcatcca aagaggaatg aagtgtcttt gatttcaatc
      301 cttgtattgt ttcaagaact aatggtgaca ataaaggaat gtcatctgcg atatgggcta
      361 aatgttttac tgcatttaag ataactgccg ctgacgcatc catcaatgaa cttgtacgcc
      421 cggtaatgat gacttcatct ggtaattcga ttgcaatcac agcagaagga tcttttgtag
      481 gactttgcgc ttgaatctta tctgcatagt catgggcagg gactaccacg tttcggtctt
      541 caggacgtaa accgacttct tccataatca gtttgattcg attaactgct tcttcgtcga
      601 tcaatccttt tttgaagtcg cattctgttt ggaaataacg acggatgatt tcttgtttag
      661 aggcttcttg gacaacggta tcatccacga tcccaaatcc tacacgattc acacccatgt
      721 cagtaggaga ttgataaaca gattctttac cagtaatttt ttcaataata cgtttgatta
      781 caggaaatgt ctcaacatcc cgattatagt tcacagctac tttattgtag gcatcaaagt
      841 ggaaggaatc gatcatattg acatctttta gatcgactgt ggctgcttca taagcaatgt
      901 tcagcggatg tttcaacgga acattccata ctgggaaagt ttcgaacttg gagtaaccag
      961 ctgcatgtcc tttttggctt tcatgataca gttggttcaa ggaagtagcg agctttccac
     1021 ttcctgggcc aggagctgtc actacaacga ttggtttagt tgtttcaata tactcatttt
     1081 ttccaaaacc atcttctgag acgatttttt ctacgttgac tggatagtct tcgatttctg
     1141 agtgtttata gaccttgatg tttcgtcttt ctagtttatt gataaagact ttcgtggcag
     1201 gctgtccact atagcgagtg ataacgacac tgttgattaa taagccataa ccacgtaatt
     1261 catcgattaa ccgcaagata tccatatcat aagtaatccc ataatcacca cggatcttat
     1321 tacgttcaat atctccagca tagacgcaaa tcagtatttc agcttgatct ttcaattttt
     1381 gcagcaattt gattttcgca tcttcttcaa atcctggaag tacacgtttc gcatgcttgt
     1441 cgtcaactag cttcccacca aattctaaat ataatttgtc atagtggttc actcgttcca
     1501 aaatatacgc tgactgctct tcaatatatt tttctgaatc aaaaccaatt tttttcacta
     1561 ggttccctcc ttaagtacta aagcattttt tcattttttt gaggattcgt caactggaag
     1621 agcgaaattc ctcaaaaaaa caaagaaaat ggtttaaacc aacttgtcta gatagttatt
     1681 cattggtatg atagtttttg ataaggaagg tgctacatga aaaaaagaca gaaaaagaaa
     1741 aacgcatata aacactatat ccgttcgatt tttaccggtt atgaaagaat gcttgaagat
     1801 cccgaattgg aacaattgac gtttacttat ctaaacgaag aaacgcagct aactcgtgat
     1861 gagcatcagc gcattcattt cacaacaaga gatctgccta gtaaataaaa aataagataa
     1921 aggtcatcgg attcgattct gtcctatcag atggaaagac tagttgatcg aaaaaaaggc
     1981 tgtaccaaat tttggtgcag cctgttttat ggagcattgc ccgctctttt ttataacaat
     2041 tttttacaga aaatggtact attgaagtat taataagtga aaaacagatg agtaagagga
     2101 ggcaagtagt atgaaagagc cagatacaaa tgcaaattat gagccagacg aactagagga
     2161 gacgaatgcg gatcaggata caggacaaga atcgtcttct ttttacgata tcaaagaaaa
     2221 agcaagcatg aatctttccc aattattaga agacttacag gcttttgaaa aagctgtccg
     2281 cgaagaagat atccctgaga tctaccgttt atacaatggc cgattgaatg aagaattaaa
     2341 aagaagctca aatgaaaatc acgagatcga tcaattgctg atgcgtaaga tccatgatcg
     2401 ttttttacag gaatttcctt ttatggaaca agtagaaaac atctcgccaa cgatgagcta
     2461 ttacaaaatc ggcacttatt accatgatcg gcccacggtc ggtattgatg caagtctgcc
     2521 agaaattttt gttttgccta agatcgatga agagtgggag aaatattccc aaccggagtc
     2581 aacggactat gacaaaaaaa tcaatgagct agacgcaaag gtgatcactg ctcagacaga
     2641 aattgaacgt ttagatgaac aaataaaaga aatcaatcga caaatgactg atttgaacga
     2701 caataaagga ttcttgaatc gtaaaaaaat cgaggaagaa attcaagaat tagagaagaa
     2761 gaagcaagta ctatctaatg aaaaattagg ctggcttcct tatattgaga cgcctgaaac
     2821 aatccagcag caaaaagaag cattgaagca agaagcaaga gcagaccagc ttcgtgcagc
     2881 catcgtagaa aaagaacaaa ggcaaatcag acgctatttc ggtagcaaag agggattcgg
     2941 tcaagcaatc catgaattct tgatgaatta tcttggcaat gagaatccta ataatcaatc
     3001 taatgaagga ggttccgagt atgaatgaac acgatgaagc agaatggaca aaaaatgaag
     3061 aacaaacaga agatcatgaa gaaacgaaca cttcattgga agaacaaaca agtaatcctc
     3121 tggatgacac agaagaaatc cctatgctag aggaaacaaa aatacacgaa aaagaaaaag
     3181 taactccgac gaatacgaat actgcagaaa acacccatgc ttacgaaata actgaaaatc
     3241 ccgggtattt agaaggaaaa gagcaagatc atcaagatat cgtcagtttg attgaaacag
     3301 cggaagcaga attagcggat ttacgtatga gaaaagattt gatcgaatca gattttccac
     3361 aattattaga atcatatgat cgttttatat tgaatgaaga accaatctcc acgatcggaa
     3421 agacaagcct gatcgaatac ttcacgtatg aattactgaa accgttgaat gatattggtc
     3481 tggaacggtc aaattcagct tatgacacat ggaaaacaag acatttttcg atcaattata
     3541 cgttgaatgg acaaaacgaa ttagtctttt cctttgtatt accgaccatc gatcaacgat
     3601 accaagtgga atcgatgagt ctcctaaacg tatcaccaga gacaatggaa atcaatgtcc
     3661 aagatgaccg ggtgctttct ttgatccgac actggtcagt ggatcgagta ttctctgcag
     3721 ggcagatcac gatattcaat cacaaattga atcaattatt agcccatgca agaacacttg
     3781 gttttaccgt taatcagaca ttactagaca atacgaagcc acttcgtttg aatcttcaga
     3841 gcgaatttga attgacgaat gaagtattgg atgatatttt tatcgtggca atgaaaaatc
     3901 catcctacga tatggaaaag atcaacgaaa ctacttatca agtacgatta gataaaggac
     3961 agtctttaac gataacaaca aacgaaaaag atcaaacagt cttgtcgatc tcatctggag
     4021 actacccacg atctgtcatt gatttcttta tcaattacga attcttggtc ccattaatgg
     4081 tgagaaagtc ctgattggat aagttggatt accagatgtc attcagataa ttctgttcca
     4141 aaggacttgc ggcagttatc cagaataatt gtcacaagtc ttttctgtat gtactaaatg
     4201 gacgtgaata acttgctgat gaaggaggga tttcattagg aatgtccaca aataaaatag
     4261 cacagcttag cttattgtct gctgcttgtg tagcaggtag gatcgctttt caatttattc
     4321 cgaatttcca gccaatgact gctatttttt tatttatagt actttactta agcttaaaag
     4381 atgcgttaat tgtcatgagt ctttctattg cgatcagcag tttttatttt ggtgttggac
     4441 catgggtcat cggccaatgg atcagctata ctgttgttct gagtttgttt tcaatcgtct
     4501 gcttgagaaa aacagtgcaa aggaatctat ggttaaaggg agtctgtttt tttctggcgg
     4561 gcatggttta cggaataggt atgaccgttt ttgatacgct gttatatcgt ttgcctcaac
     4621 cttggatcta ttaccttcaa ggggtgtcgt ttgatttgat gcacagtata ggcaatgttg
     4681 tgttctttct tgtttttctg ccagtcgtca aacgttttta caatcattca ggaggaaaaa
     4741 atgaaaaaaa taatttatag tttgcttgca atgagtgtca gtatactcat tttgacaagt
     4801 tgcagtacaa cctatacaca atcggcttcc aaccaaaagg aggaagtaaa aacatcgcaa
     4861 aaagcaacaa tcacgttaca agaaaatggt caaaactttt cggaaaaaga agtgttcttc
     4921 aaaaaaggcg atgatttact gagtattttg aaacgaaatt ttgaagtcaa agaagataac
     4981 ggcttcatca cttcgcttga agggcactca caggatgaga aaaatcaact ctattggatg
     5041 tttactgtgg acgggaaaag tgctactact ggtgccaaag agatcaaatt gaatgatgga
     5101 caatcggtca ttttcaattt gtctaaacta taagtttcat aaaaaactgt taaagggcga
     5161 atattgccat aattcagtga gttcagttga tgaaagaagg aaaataacat ggaaaatttt
     5221 aaaaaaagcg gaatgttttc cgtaattgct gctctagggg ctaatattct agttgctatc
     5281 agcaaatttg tcggctatgc aatcagtggc agtgccgcca tgctaaacga aagcatccac
     5341 agtatcgttg attgcagcaa tcagattttg ctgttattcg gtgataaaca agccaataaa
     5401 ggacagagcg agttgcatca atttggtgaa ggacgagcaa aatacttttt cagtacaatc
     5461 gtcgcaatga tgcttttctt cggcggtggg gcacttgggg tgatggaagc ttttgaaaag
     5521 ttgacgcatc catcccatga agtgggtaat ccgatcattg ttatagcaat actgttattt
     5581 ggtttggtaa tcgaaggaag ttcgttacgc gtggcaatga aagaaatcaa agaattgaat
     5641 actgaaaaac tttccacgat gcgctttttg cgcgaaagtc gacacagtga aatactgatt
     5701 atttttacgg aagacttgtg tgctgtaatc ggtttggtct tggctttagc aggaacaata
     5761 ttgacttatg caaccgggat tgctgcattt gatgcgatca gcggattgct gatcggtttc
     5821 ttgctgatgg gagccgccat tttcctagca aaagaatttt atagtctgat catcggtgaa
     5881 agcgtgacag caagcgattt atcaaaaatc aagttagctt ttgaacgtcc tgagatcagt
     5941 cggctgatcg atataaaaac agttcattta agtccaacgg agattttagt tgcagcaaaa
     6001 gcagatatcg ttggtaacaa agagaatgaa gcttactcgg tcatcaatga tattgaaaaa
     6061 aatatgcgtc agtctcttcc tgacaagaag atgtatatat acattgaaac agataaatat
     6121 gacccaaatt attctcgtaa ataaaacgtt tattcatgaa ttgaagcaaa aatgagaaaa
     6181 atataatctt gtttttaaat aaaacggcta caatttagcg aatttatgtt acaatgagtc
     6241 cgctgtttat ttgttgtaat taaaggagat attttaatga acaaaaagaa aagtgcgcca
     6301 tggcttcaag ctttgcatgc agtgatgcca ctttgtataa gctatatacc agtaggatta
     6361 gcttgcggag tattgttgca aaaagttgga tttgatcctc tcttatcagg actgttatcg
     6421 attctggtct tttccggtgg cgcgcagttt ttagttgcat ctatgcttac gacgcaagca
     6481 tcatttgcaa cgacattatt gatggttttc tttttagaat tacgctatac attattagga
     6541 gcaagtcttg ccggttttat gaaaaaagaa aagcggacgt ttttggctgt cttttctcaa
     6601 tcactgaatg atgaaaacta tgcggtgaac tacttaaagt tttcaactga cccttcctgg
     6661 aataaaagaa aggctttata tgtcaattgg ttctcaatga ctgcatgggc cggtagcaat
     6721 atgatcggta attttttcgg ctcggtgatt cgagtagatg ctgaccttgt ccattttgct
     6781 ttgacggcca tgttcatttt catgtttatc atgcagatga aaagcgcact actgatcttt
     6841 acaggtttat tctcaggcgt attaggggtc gtattcatgg tattattcca aaatactttc
     6901 ggattgattg cagcaacagt cattgcttca tttgccggat ttatgctgga gaaggcattc
     6961 aaaaaagaaa aagctaagaa actaagagac cgcggtaaag atgtcaatga gccgctcttc
     7021 aacttcccgg aacaggaggc caatcaccat gactaaacta tatttgctac ttttagttgc
     7081 ttgtctgttc atcgtggcat atatcccgcg cttgttcccg atgctttatt ttactcatcg
     7141 aaaagtgcca tcctggttca gtgactggat gaaatatgta ccggtggcat tatttgcggc
     7201 gttagctttt aaagatgttt tcattactca tgaacatctg gatattgctt ggaatatcaa
     7261 aatagctgca atgattctag tagcaggcgt ggcttacaaa acacgttcga tggcgttgtc
     7321 agttttgaca ggacttgcgt ctgtcttttt gctgtctatg ctttaaactg ttttatttta
     7381 ttaaaaacag agattgcgac ataagttgtt caaactgatc tatccgaact gcatttgcaa
     7441 cagtcaattc tggatgcaag tttattcgta gggataaaaa agattagtgt tggcttatga
     7501 tgcaagctct tttttatttt aggaattaga gagggatttg tccttctatg attttttgct
     7561 ataataggga agatgtttat tttatgaaag aatagttgag ggaatttaaa tgaataaaaa
     7621 attgatgcaa ggaacatttt ggctaacctt tgctaatctt ctatgtaaag ttttaggggt
     7681 agtctatttg attccctggc taagtatgat ggggaacaat caagatggta tgcttgctac
     7741 gacattgtat aatgttggct atcttcctta tggattgttc ctgatgcttg gtacagtcgg
     7801 atttccaaat gcgattgcaa aaaaagtagc tgtagccaca aaagaaggag ataacgctgc
     7861 ttgtcggctg atttttagaa gtacgatcaa tatcatgttt gtcatcggta tcgcctctgc
     7921 tgcactgatg tatttatttg ctcctttact agccggaatc agtccgattg ctaacgttaa
     7981 taatgggata ctagctatca gaagtttatg cccatctttg attgctatcc caattcttag
     8041 tgcaatgaga ggatatttcc aaggaaaaaa tgatctgcgg ccttatggaa cttctttgat
     8101 tatcgaacag gctgtgcgag tgatcgttat cttggctggt acttattact tgcgcgtatt
     8161 gactgacgga accatattag aagctgtatt gatcagtaca gtcgcttctt tcttcggtgg
     8221 gttagctgcg attatccata tgtatatcgt cggacgcaga aaagacttct tcgaacttaa
     8281 agattttttg atttccagcc gttatttcga aagagaaaac cgatctgcct ctgtctctat
     8341 cattcgggaa acactaccgt ttatttttgt cggctcagtc attactatcg ttcaaatgat
     8401 cgaccaagta acgatgaaac cactgcttca ctttttccgt ccagagatcg cagatcagca
     8461 actggaattc ttattcagcc gtgcttctgt caatccaaat aaattgacat tgatcctgat
     8521 ctccatggta ggaacagtag ctataagcag cttgccaata ttaagcacga tgaagaaaaa
     8581 agatcggata caaatcgaaa aaacagtagg agatagtttt tcgattgcgt tattgattct
     8641 tcttccttca ttgactggaa tgtctttatt agctggacca ctatacacat tgttttttgg
     8701 ctatgatcct gaaagtgtcg gatatttcca aatggctttg ctagcttctt tgtttttctc
     8761 tttattcacg atcctatcta cgatgcttca atctttgaat caccatcgtt ttgcgatccg
     8821 attaactgta gaagcaatta tcctgaaagt catcttccaa gtaatcggat taggattagt
     8881 tggcggatac gggatgagct tatcaaatgg cttagcattc ggtattgtct ttgttcgcgg
     8941 ctatcacttt atgtgcaaag aataccgaat agcaccttta gcaaagatca gcaatttttt
     9001 cttaaaaact ttccgctcca ccctgattat gcttgcagta tgttttgccg ttttcttttt
     9061 gctgaatcag cgattgtcaa tggaatcaaa aagctatgca atgatttatt gtgtggctgt
     9121 aggaagtatt ggcggcttag tatttttatt ttctcaattc ggaaaaaatg ggtttcgaat
     9181 gttgaaaaat gttaaacatc atagcagaag caaagaatag gttaactaat cgttttttgc
     9241 tgtcacttga aaaacggcaa ctcgtatgat tacgcttgtc gtttttctat tttccaattt
     9301 tagtttcata tctaatctta cttatgatat agttataagg tctggaaaaa ttctttgaaa
     9361 cgaggaaatt aaacacatga aacttgcagt agttacagat agttcggcat atctgccgga
     9421 acgtatcaag aaccatcccg acttattcgt tattccaatc cctttgatta tggatgggaa
     9481 aatttataac gaaggaatcg atatcgaagc ggatgaatat tatggacttt taaaaaacag
     9541 taaagatttt cctactactt cacaacctgt cgtaggggaa gttttgggtt tatatgagga
     9601 attgaaagag aaagggtatg acacgatttt aagtatccat ctttcttcag ggatttctgg
     9661 ctttgtcaac acattatttg cgatgaaaga tgacatcagc ggagtaacgg tcattcctta
     9721 tgactctaag atcactagta tgccgatggg acacatggta gaagctgcct tagacttaaa
     9781 tgatgaaggt cagtcccttg atgaaatact tgcacatatc gatcgaatcc gagataatac
     9841 ctacgcttat ctgattgtag atgatttgaa caatttagta cgaggaggac gtttgacaaa
     9901 tggtgcagcg ctgattggca gcttattaaa aatcaaaccg atcctgacat tttctgaagg
     9961 gaaaattgtt ttattcgaaa aaatccgttc aagtaaaaaa gcatttgctc gagctgaaga
    10021 aattattggt agaagaaata acgaaataca accgccagtc aaactttacg tgatacatgc
    10081 aaataattta gaagtagcga ttgcggagaa agagaaattg cagaaaaaat atccaaatgc
    10141 agaaatcgaa attggtcatt tcggaccagt cattggtaca catttaggtg aaaaagccat
    10201 cggcattgcc atttcagcgc aataattcct tttattcaaa aaacatacca aaaatattcc
    10261 aacatcatct tggactttct acatgttact aatgagcgtg taaaagaacg agatggtgtt
    10321 tttatttcta tcaatgaagc tctttttctt tgcaatcctc acttcaatcc tctataatgt
    10381 cgcatatagt ttagtaaatg agtaaactac taatttactt atttactaaa aataaaagga
    10441 tgaggagtta aaataatgga aataccaaca aatttaaaac ataaaccagt aatcgttgta
    10501 gaagactatg ataaagttga tggaagaaat gcattaaata cggatgcaaa agggctttca
    10561 ctgggccttg ctcagtggaa tgatcgtgga aaagtcgata tctcaggcaa ggtatggcga
    10621 catactggag aaaaatggtc acgacagtcg gaagaattac caatcacacg tattttagat
    10681 ttagcgatct tagctgcaca aggaagttta tacttccaag atgcttatcg ttatgaaaaa
    10741 ttttatgatc cagaaaatcc agtcgtagac atcattggat tacaagggaa ccgaatgacg
    10801 gtagaagtag ataccaaaaa tccaaagatc gatgaagaca tcattttgta ttacgataca
    10861 ctacaaaaag acggagaact gattggggaa cgattccgta ttttaaaacg tcttttagat
    10921 gagctaggat attaatagac agagatgatc aaaaggggaa gagaagcatg gagaatttct
    10981 cactaacaga aaaccgaacc ttttcacggc tagaaaagca aatgatctgg aagaaaccga
    11041 aaagccatcg gacaagtgca gaagaatggc ggatcgcctc cgaaatcaaa gggaattggc
    11101 aagatcctga aatgaaaatc agtaacgtac ttttggaagg agatgccggg tcggggaaga
    11161 cacaattagc caaagcacta tctgctgatc tgcaacttcc ctatacaaaa gtgacctgtt
    11221 ttgcagatat ggacaaatca gatgttttcg gagccttatt acctgtagta gattctaata
    11281 aggaacaaga ccaagaatta ctagaagcta tttaccaaac agatacactt gaagctgtac
    11341 tgacactgat ccagaaccat tacggcattg atcctttttc tgctaaagaa aaattagcag
    11401 agctagttca aaggatcgaa gctgattatc cagatgcaat ccattacagc tattaccctt
    11461 ctgaaatcgt tcgagcgatt gaaaaaggat atttattaga gattcaagag ccgactgtca
    11521 tccgagatgc ctctgttctt gtggcactta actcagcgct cgaaccaaat gggatgttga
    11581 atttaccgac aggaatcatt cgtcgccatc cagattgcgt cattgtgatc actacaaatc
    11641 gaaattacca aggaaatcgc ccattaaatg aatctttaag agatcggatg caacatgcgg
    11701 aaaaaatgga tcttcctgcc ttagaagtca tggcagaacg tgcgatggcg aaaactatga
    11761 tccaaaaaca agaacttctc ttaaagatgg cagagattat ccgtttgttg gatgaaactg
    11821 caaaagctaa cgccatcaaa ggtgtagcag gaatgcgttc ttatttttat tgggcaaata
    11881 cctataagca aggacaagat ttactccagt cgatttatcc aaaagttttg tataaattat
    11941 ccactgattc agatgaattg gcaattcttg aacaagcttt gtctgacagt ggattgctac
    12001 tggaacttca ggacatattg agaaaagaaa aatggggtca tcctcaatct gagcatacaa
    12061 aaggaagaac cattagcgcc gaagaagcaa atgaacgaaa catcactgaa aatgctgaag
    12121 aaattctgcg cttagatgaa aagaaatcgt tgtctgctga agaaccaaat gagggagaag
    12181 agaaacaaga agaaacaata gaaaaaaacg agattcctcc tcaaatgcaa aaagaacgca
    12241 gtagcgatat cgaaggaaaa aatcaaaaag aacaacaaac aggagatgat tctcaagaaa
    12301 tgtctgcttc tgacatggaa gcacatgata aggaaatcaa gaagcaactg aataaagaag
    12361 cgcgacaaat catgaaggaa acgattcatg aaaaagaagg tctcatcgtt caccgaccag
    12421 ctttccaagg aaaaacgccg gaagcacgtg agctacacat gcaagtaatg ccaatagtag
    12481 aatcacttag ccggcaaatt ttagagttac tggataatga acaaacagag acgtaccaaa
    12541 aaggaaaata cgaaggtcag cggttcaatg caagcaaagt agcatatggt gatttgagaa
    12601 attttgacaa aaagaacccg ccacatgagc aaccttcttt agcggtagct gtacggatcg
    12661 atgaatctgg gtcaatgata cgggatgatc ggatcgaagc ggcaaaaaaa gcagcgattg
    12721 ccattgccga attttctaag aaagtcgata tcccattgtt gatttacgga gatacagcag
    12781 accgttcgtc aagagaaaag acttctttgt tttcttataa agaatttgaa gacggatttc
    12841 aatggttaaa tgaaaaatta gtcactatga aaccaaggca aaacaatcgt gatggtgctg
    12901 cacttcgttt agcagcagaa aaattaaaca gacaatccgc aacaaccaaa ctgttgctta
    12961 atattagtga cggtcagcca aaagcgttgc cggattatac aggcaaaaaa gcaaaagaag
    13021 atatccagtc tgttttgaaa gaatatgaac gtcaaggaat cctatttgtc tccgcagcta
    13081 ttggccaaga caaagaagaa atcaagtcga tctacggtga aagtcgtttt gtagatatta
    13141 ctgacttgaa tgaatttccc aagcaaatga ttcaactgat tgcccgctat ctatgataaa
    13201 ataaagctca acgaacgcac ttagcagatt cgttgagctt ttcgtttcta gttaccggta
    13261 acaaggatac ttctaaaata gaatcggtta taatcaagag ggaccgttaa aggagtgaaa
    13321 cgatatgata caagaacaaa aatggtggaa agaagcagta ggctatcaaa tctatcctgc
    13381 tagtttcaaa gatagcaatg gcgatggtca aggagacatc aatgggatcc gtgaaaaact
    13441 taattatttg aaagatcttg gtatcggctt tatctggatc aatccgatct atcaatctcc
    13501 atttgtcgat aatggttatg acgtaagtga ctatcaagat atagaagaga gattcggaac
    13561 gatggaagat tttgatttat tgctaaaaga agcacatgaa ttagggatca aagtgattat
    13621 ggatcttgtc atcaaccata gttcggatca gcatcaatgg tttgaagaat cgaaaaaatc
    13681 taaagaaagc ccgtatcgcg attattacat ttgggtcgac ggggtagatg gcaaagaacc
    13741 gaataattgg acatcgattt tcggcggttc tgcttgggag tattctcatg aaactggaca
    13801 gtattatctg catgtttttg caaaagaaca accagactta aattgggaaa gcgagaaatt
    13861 gaaagaagaa ctattcaata tgatccgatg gtggttggat aaagggatag atggatttcg
    13921 tttagatgcg atttctcatg taaaaaaaga tgaatattca gtaaaagcca cagagaaccc
    13981 tttctcaccc tttcaaaatg tctcaggaat cgaagaacat ttgaccgatt tgaaacatgt
    14041 ttttgaagag tacgatatca tgactgtcgg agaagcaagt ggtgtcactg cagaagaagg
    14101 accacaatgg gtagggaaag acggttattt cgatatgata ttcgaatttg atcatatcca
    14161 tatctggcag caagaaaaag aagggcaatt agatgtcctt aaattgaaac ttgcattaag
    14221 cgcttggcaa acttcattgg atggtatcgg atggaacgct ttatatatgg aaaaccatga
    14281 tgttcctcgt gccgtttcag tgtttggaga tactcgtccc gatttttggg ctatgtctgc
    14341 aaaagcaatc gctatgatgt atttcttttt gcaaggtacg ccatttattt atcaaggaca
    14401 ggaaatcgga atgacgaata tgccctttga atcgatcgat caagttgatg cagtagattc
    14461 gaaaagactt tataaaaggc tgcttgcgga aggtaagaca agagaagaag cattggatat
    14521 cattcgtgaa acaacgagag acaacagcag gacacccatg caatggactt cggaacaata
    14581 tgctggtttt tctacacatg aaccttggct gatcactaat ccaaatacca aaacgatcaa
    14641 tgtagaacaa caagaatatg aaccagagtc ggtcctgcaa ttctataaga acatgatccg
    14701 cattagacaa accaataaag gtctgatata cggttcttat aaagaatatc ttcatgaaca
    14761 tccacaactt tatgtctatg aaagatattt agaagatgaa caatatctta ttatggtaaa
    14821 cttaacagaa tcacttgctg actatgaact tccaaaagaa gcagatcagt cctggacatt
    14881 actcttgtca aattcctcta gcggagaatt tgaagctaaa ggcatactag caccttatga
    14941 agctcggtta tataaaacaa acaagtaaaa cttcctcgtt aaagttcatt agttggactt
    15001 tgcgaggaag tttttcagat tgctctgtca attactcatt tcaataattc gctctaggac
    15061 caccgatata tttaggacga gagcgaaggg ctgtcacgtg agcttgtcca agggttttca
    15121 aacgaggtct gacaggtact tggacatgtt tgatatgcat accgattgat gtgtcaccga
    15181 tatcgatacc ggcttgtcca actacgtgtt ccacttcgac aggatcattg aactggtcaa
    15241 aagcagcaac agaacaagca cctccagcat gtagtgcagg aacaacagag acaatttcga
    15301 aattttttgc ttctgccact gttcgttcta ctactaatgc tcggttcaaa tgttcacaac
    15361 cttggacagc tagcgcaatt tctttaggat ccaacaactc ttttaacgta cggatgatcc
    15421 attgaccaac ttccgcactg gaattttttc caatatgtcc tccaacgact tcgcttgtgc
    15481 tgcatcctaa aacaaaaaga tcaccttttt tcaagtgtgc ctcagccaat atgtcattaa
    15541 ctatttcagt caattggtct tttaattctt tttctgacaa cttcattttc taaaaccttc
    15601 tttttcaatt aatattgctt ccgtgcttga atacgttgaa gacttgcagt tataggaaag
    15661 gcaagtccca ttccaatcag attttggaag atgtttcctg gtatagaagc cactccagcc
    15721 ggccaatcat ataaaatcca accggcgata ccatagccga tgatcataac taagcttcct
    15781 aataaaagcc ctaatcccca catacgagta gaagatttgc tgaaagaacc agcaacatat
    15841 ccttgtaacc cgtggatcac taatgaaaaa actgcccact gcggatatcc tgaaatcaaa
    15901 tcgatcaata gaccactgga agcaccaaca actaatccac ccgttggacc ataaagaaaa
    15961 gcagcggtat agatcccggc ctcgcataat gtcacaaatc cattcgtagc cggtacaggg
    16021 atcaaaattg ttaatgaaag ggcaactgtc aacgcaatca gcatagcata gatcgttaat
    16081 tgcttagttt tcatttctca ttcctccttt ttgaataccg ccagaccaga cacttccggt
    16141 atgatcgttc atcagcacgc cattagaaat acaatgggca acaaattttt tactttctgc
    16201 tactgctttg gtaaaatctg cccctaacac aagattcgct gttattgcag aagaaaaggc
    16261 acaaccggcc ccgtttactg ttgtagtgtc gattttttta tgagaaaata cctcataatg
    16321 atcaattgaa tagagaagat ccacagcttc atctccagcc atccttgtgc cgcctttgat
    16381 cacaatgttt tttgttcctg aagcagtgag ttctttagcg agatggatca tttctgttaa
    16441 cgaagaggga agagcttgac cagaaagtaa agcagcttct gccaaattag gcgtaatcat
    16501 cgtaacaagt ggaaaaagtt cttcgatgag ctgcgaaata tacaattgat tgatcacagc
    16561 ttcagtttct ttgaatgcca aaacagggtc taaaatgatt gggatatttt gttttgtttt
    16621 tatgaagtct cgaacaacca tgattgcttc acttgaattc aataacccaa ttttgatacc
    16681 atctaatgaa gtcattttat caatcgaaac taactgtcgt ttaagcaatt ccaaagatat
    16741 agattccagc ataaatcgct cattaatatc tagtgcccct atagaagtca aggcgcttag
    16801 tccgaataga ccaaaattct caaaagtttt taaatctgtt tggattcctc caccagcaaa
    16861 tggatcagaa ccgccaattg tcaagattct tttcataaca ttttcctcca tgaataagag
    16921 tataacgaaa ttttcaaaaa agaaaaacag ccaattggca tatttttatc tcatccaatt
    16981 taaaaaaaca aaaagaaaag aaagaccaaa atggatcttt ctttccttaa atagttagga
    17041 cttttgtgat tttaattctt tctcgatttg aagccgttgc actttcattg tagctgttcg
    17101 cgggattgca tcaaaatcac ggatgatagg gacgttcaag cgaggaagtt catggacttg
    17161 ctcccaccat cgattccaat ccatttcttt atcaggagct aaagcaataa tcggttgtgg
    17221 agaatgattt ttatccctta caatcactac ttctgccaaa aaatctaacg aatctaataa
    17281 aaagtcttca atagctaatg tactattgat cgtttcgatc aaatccactt gccgatcttt
    17341 caaaaatagg tggccatgct tatccataaa accgtaatct ccgctatccc accaatcgcc
    17401 ataaacattt tcctggaacc gtgcatcttc cttgtaataa gtcaaagccc gtcctttaga
    17461 cagtaattgt atatgaccat ctgtgttttc aggtaggaca ttcccaactg aatctgtaat
    17521 ccgagcgctt gtcatgtctt ccagtccaac gcccatatct cttgcatcac ttgttttcaa
    17581 actctctagt gtatgagcct taagaatcat tggtccgcat tcactttggc catatacttg
    17641 aagaaatacc gcatcctgtg ccatcgacgt tcgcaaaaat gtcttcattg tctggttgtt
    17701 tatagcatca aaagtggagt gatagtatcg gatacccgaa aaagcttctg gatgctcctt
    17761 agcagtaaaa cgccactgaa caaagttatt cggatgggtc tctagtgcaa ttggccggtg
    17821 agcttccaac atatgaacaa cttttgaact ttgtgcgttt gctaaaggca tcataggaaa
    17881 tcccatggac atcaaagaag agataccaat attgaatctg gaatgcactg gagagatgtg
    17941 aaaagcgatt aatttctttt ccgaaatttt tgtgaaaact gttttttgcc atttcgtccg
    18001 ccatcccata gaatgagcag aatgacaaat aagtttaggg ataccagttg taccagaagt
    18061 atgggtcata taagaaattt catttttgtc taaaaatgat tgagaaacag acaaagcagg
    18121 ttgttccatt aaataaagaa taggaa
//
LOCUS       DAZUJR010000061        18118 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.061, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000061 DAZUJR010000000
VERSION     DAZUJR010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18118
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.061"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(161..445)
                     /locus_tag="ACG804_001985"
     CDS             complement(161..445)
                     /locus_tag="ACG804_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832910.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(463..1353)
                     /locus_tag="ACG804_001986"
     CDS             complement(463..1353)
                     /locus_tag="ACG804_001986"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YicC/YloC family endoribonuclease"
                     /protein_id="HFS4832911.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(1373..1591)
                     /locus_tag="ACG804_001987"
     CDS             complement(1373..1591)
                     /locus_tag="ACG804_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HFS4832912.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(1561..3241)
                     /locus_tag="ACG804_001988"
                     /pseudo
     CDS             complement(1561..3241)
                     /locus_tag="ACG804_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
     gene            3508..4281
                     /locus_tag="ACG804_001989"
     CDS             3508..4281
                     /locus_tag="ACG804_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832913.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(4362..4931)
                     /gene="thiT"
                     /locus_tag="ACG804_001990"
     CDS             complement(4362..4931)
                     /gene="thiT"
                     /locus_tag="ACG804_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015234 - thiamine transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015888 - thiamine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HFS4832914.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(4997..5099)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(5105..6076)
                     /locus_tag="ACG804_001991"
     CDS             complement(5105..6076)
                     /locus_tag="ACG804_001991"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFS4832915.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(6170..7543)
                     /gene="glmU"
                     /locus_tag="ACG804_001992"
     CDS             complement(6170..7543)
                     /gene="glmU"
                     /locus_tag="ACG804_001992"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HFS4832916.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(8046..8864)
                     /gene="purR"
                     /locus_tag="ACG804_001993"
     CDS             complement(8046..8864)
                     /gene="purR"
                     /locus_tag="ACG804_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HFS4832917.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(9031..9855)
                     /locus_tag="ACG804_001994"
     CDS             complement(9031..9855)
                     /locus_tag="ACG804_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HFS4832918.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(9828..10508)
                     /locus_tag="ACG804_001995"
     CDS             complement(9828..10508)
                     /locus_tag="ACG804_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFS4832919.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(10531..11469)
                     /locus_tag="ACG804_001996"
     CDS             complement(10531..11469)
                     /locus_tag="ACG804_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HFS4832920.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(11714..12565)
                     /gene="ispE"
                     /locus_tag="ACG804_001997"
     CDS             complement(11714..12565)
                     /gene="ispE"
                     /locus_tag="ACG804_001997"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050515 - 4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HFS4832921.1"
                     /translation="MELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADHLFFE
                     EITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAGLGGG
                     STDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQVLPS
                     MPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMGNSLE
                     DITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGFCEEV
                     YLVRTLQ"
     gene            complement(12719..15292)
                     /gene="mprF"
                     /locus_tag="ACG804_001998"
     CDS             complement(12719..15292)
                     /gene="mprF"
                     /locus_tag="ACG804_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HFS4832922.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLP
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            15433..16239
                     /gene="proC"
                     /locus_tag="ACG804_001999"
     CDS             15433..16239
                     /gene="proC"
                     /locus_tag="ACG804_001999"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HFS4832923.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(16318..17874)
                     /gene="rny"
                     /locus_tag="ACG804_002000"
     CDS             complement(16318..17874)
                     /gene="rny"
                     /locus_tag="ACG804_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HFS4832924.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
BASE COUNT         5227 a         3903 c         3108 g         5880 t
ORIGIN      
        1 taataccgag aaaatggttt ttgaacatca cttattcaaa ataaaaaaag attgtgacac
       61 gaattttgtc acaaccttta aatgtattcc tagagcaaag aagctaagcg aagaaatcca
      121 attctgatta tttattgtat ttctttgttc agcatccttg ctaaaagccc atattggaca
      181 aagtattcac tacacccatg atctcatctt ttcgagaacg tgctttttct gtcggatctt
      241 ctacctcttc tgtgtcaatt cgaacaataa atttccgatt catcgtcacg taagcaccgt
      301 cgttgatcaa aataaacagt tcgttctcat tatagtctgc acaggcatct ttccatacgt
      361 caaagccgtt tttttcagaa gggatatccc gtttaaccac agtttttcca cttaattcgt
      421 ggaacgttac gtcataatat ttcattatct ctacctcttt cgtcattcaa tattttgtac
      481 ttgttctctg attttttcta agatcgtctt agactggacg acttgatttt taatttcgat
      541 tgcatttgat ttggaaccga tcgtgttgat ttcccgattc atttcttgga tcaggaaatc
      601 taattcccga cctacaggac attgtgcttc gataagttca tctagttttt gtacatggat
      661 cgccagacga tccagttcct cgtgaatatc tccgcgttcc aacaagatgg ctagctccgt
      721 caacaaccgt tgctcatcga ctttcgctcc aagaaattcc tccagctttt tttgatacct
      781 tatttgaaat tccttttcat agatttctac aaaactatcg agttttttta gtacttcttt
      841 gaattcttca gtattctttt tcaacactaa agctaaagct tgaccttctt tttctcgact
      901 cgcctcaata gaatcaagtg cgcttttcaa tgtatctaga gctaactgtg ccaattcttc
      961 catgctctct tccggttttt cttctaccgt tacgaagttt tcgtccagcg cgaagcgttc
     1021 cgccatccga ctaattgaca cttgattttg actaccgtat cgttgttgaa ttccgtctgt
     1081 caattgagtg ataagtgaat caatcaattc ccagttgatg acgatctgtt tttcgttttt
     1141 gccaatataa gctagattca caaatacttc gattcgaccg cggcttaact gctgtttaat
     1201 aagctgacga aaatcgtttt caacaaagtt caggatttta ggacttcgta tttgaacatc
     1261 tagaaaacgc tggttgacac tttttatttc aatatctaac tgatacgctt ttgtttcgcg
     1321 gatggctttg ccaaaaccag tcatactttt cattcgacag ggtccttcct cattacatat
     1381 tttctattgc tttttgcagt tgttcaaact cttcgttcgt caatgtcagg cctttcccca
     1441 ttttttcatg gtctggcgcc caatctcgaa gatcgaattt tggcgggcga ccattccagc
     1501 tgactaggtt cagttcttta cgccacccct tgttgttttc tgacaatata gcgatttctt
     1561 ctacgatttc atatgaaaat tcttgtgcca tggttgttcc tccttgagat aatataaata
     1621 taggatcagt aatgtgtcaa ctggttgctt aagcaattca tgctgcaaac gatccttgcg
     1681 ttttccttgt agcagataat caaaataaac agttttcgtg cgctcatttt gtattttttg
     1741 ctggtatttt cgataccttc gccattcttc agtacttaat tgaccaattt gtgccaataa
     1801 atcatccggc atacttttta tatcttgttg gcagatcatt tgaatcatca tgtctacttg
     1861 atagatttca ttgggcagta aaaaatgttt ttttgctaaa agttctagca tcgccaatcc
     1921 gcatgtctct ggtacgaccc tgttcttata taaattacgc agtttttgcc aaaattttat
     1981 gcttttgaaa aaagataatt ctaactgaat ttcttttgtt aagtaagaca aaaatcctcg
     2041 ccagtatgtt cttgcaggtt taacagaatg aaatgtatac cagttcccat agtaatagcc
     2101 taatcgtttt ttcatttcca gatagcctaa ttgtaaattt aattggttcc tttggctatc
     2161 aaaaagcaga aagctgccta gtgtccacaa tgtttgacat ttccaatgga taaaaatgtc
     2221 tggcatacga atttttttcg ctgggcctgg cccttgcaca tctacgacaa atgcctctgt
     2281 tgctcctttg ttaatcgcaa tatcaatagg tattttgttg cgatacccac cgtctgcata
     2341 tttatttttt ccgatctttc gataagccat agcgggataa aatgaagcag aggcgagtat
     2401 ccaatctggt atttcttctg tttttgtctg ttggatatca gtcactactt ccgctagttc
     2461 tggcagttta gtagacaccg tatataaacg tattttggga ttatgtttga gtaaggacaa
     2521 atccaaattg tctttgacca tcttttccaa tggagcagaa gaaaccccgc cttcaattag
     2581 tgctgttttc gtcatttggc gtctttctcg atagaagcgt tcacgaaggt cttcaactgc
     2641 agccatttct ggtaacgcaa gcacttgtct tgtcgacagc ttttttcata tctccttgta
     2701 aaatcaatgc gccgttcaac gcacctaccg aggtacctgt gataatctca aagttgatat
     2761 catgttcctt cagcgcctgc cacacaccaa tctgataagc accgtgcgct cctcctccac
     2821 ctaaaacaag tgctgtatga tagaccagct ttttatttaa ttgtgtggtt ccttgatagc
     2881 cgtttttatg aaaaatacgc aaccattctt ctgatagagg agattgaaat aaaaaacaac
     2941 agttttcttt aataaaaaaa cgagcgcaag cttccatata ccgaaaaaat tttttccatt
     3001 caaaagtttc accttcaatc aacagattat taaaaataac atctcctcta cttttagcaa
     3061 tagtaaaata gacggtatat tttttcgata ctgctttaaa agcacattgc ttttttgcag
     3121 aacgccaaaa agcgtctcta ctttcttgat gactttgaaa aaatggaagg ggttgttttg
     3181 cttgctggat aggcgaatac agcgacattt tctgtgaaaa gtaaactttt tttatctcca
     3241 tcgcgctctc ctttttcttc aagtatacca gtacgtcata aaaaggtcat gagtctcgta
     3301 ttcgactttg tagattccat aagaaaacaa ttcataaaac ctcctttaaa taaaaaaata
     3361 caaaaatcac aaaaattaat tgaaaatgag agtgttttca atgaaaacgt gattttgtaa
     3421 tggaatttta aaataaaaga aacaagcttt tttaatgcaa atgttgtaaa ataaaagaga
     3481 ttaagaggaa ataagaggag gaacatgatg actgagtcag tttatgtaca tattgatacc
     3541 acaagtaatg ctgttttaac aaaagggctg actgctactg actttgcaaa cagtatcgtg
     3601 cattttcctc aaaacttgct cttgcttgat ccatctgctt ctgctggaga atatgaatcc
     3661 catacagggc tgaaagtaat ccgtggtaca gaaaatattc agcgtttctt ttcctcttct
     3721 cgtaacaggc gtggattcga tgaattgaag tggatcgact ttactgattt aacgatgctg
     3781 aaagaattga cacctttaga aatttcagaa ttattatatt ttggtcatat gaaaacacat
     3841 cttcattcgc cgttttttta taaactacag aataattttg tatacttcga tcttaatgat
     3901 cagctgaatc ggatttatta tcgctattta gatgaatttt ataggatttt tgctagtaaa
     3961 ttaagttcga tcttgtcaga taagatcaat gtaaaaaaat cttttttcaa aaaagaaaca
     4021 cctgttgaaa aaatcagtgt ggaattattg aaagaaatgc gtaatttgat gcaggaaggg
     4081 atcatttttt cttttgatca agttggtttg atcgatggta aatatcgtat cccaatctat
     4141 gtgattgaag attatatttg gaaattaaaa ggcacccggt atcgagaaga ggaaatcatc
     4201 gctactttaa tctactctgt caccgatcga cactggcaat tggtagaaga tgccgatctt
     4261 tcttatctgc cattgaagta gatctatttc ttatcaaaaa ataaaaagga aacaagaaac
     4321 taggacatga ttctgtctca agtttcttgc ttctttttta tttacagctc ctgtcgttta
     4381 tctggcacaa aaatcgaagg agtcgtttgt tggatcccta ataaaacgat gatcgttaca
     4441 atagctgtac tcaacccgct ggcaccattc attacgaaag aaaagagcca aggattcatc
     4501 ccccatagtg catacgctcc ccagaaaacc actcctgcaa taaaatgcca aaaatatctg
     4561 gaaagtgcgc caatcaatgc accaaacacg atgctttttc taatttgttt cgtattatcg
     4621 tctacatagc ctttttggac atttgaagcc atgagccctg ctgcgcctgc aaaagtatag
     4681 gcaatcgggt actcaatcaa cacttgaacg acacttaaat aataaacttg tcccaacgga
     4741 aaatgtagga tgccccaaat gaaacctgcc agcatccctg cctttgtccc tcttcttaac
     4801 gcaaaaagag tcaatggaat ctgccctaat gaaatagaaa aactgctgcc gatctggatc
     4861 ggaatcaacg acaacaccat cgctaacgct gcaacaatcg ttccttctac ccaaactcta
     4921 ttttttccca taaaaaaact tcctcctttg aataaaaaag tcacaaagga ggaagcagct
     4981 ttcgaaaata gtcaaacagc tgtttattca caattcctac gctcgcataa ccgatacagg
     5041 tacgaagggt ttagaaatag attcaatctc agcccaattg gactcccctt tgtgagttta
     5101 tttattattt attttttgtt tcaaacaatg gactaactgg tttgttttca tggatacgtt
     5161 tgattgcatc tcccattagt ccgccaacac ttacttcatc gattttgtcg attttacgat
     5221 cttctggaag atagatcgag tctgtaacaa ctagacgctc gatagctgaa tcttctattc
     5281 tttgtaaagc agggccggat aatactggat gtgtacatga agcatacaca ctagttgcac
     5341 cagcttcttt caaagcattg gcagccaatg tgatcgtacc tgctgtatcg atcatatcat
     5401 cgatcagtac acaagttttg cctttgactt gtccaatgat attcattact tctgcaacat
     5461 ttgcttttgg acggcgtttg tctatgatcg caatcggaga tttcaaaaat tccgctaatt
     5521 tacgtgcccg tgtgacacca ccatggtctg gtgaaacaac gacaacatca tcgcctttga
     5581 ttcctttttc taagaaataa ttggcaataa gtggcgcacc catcaaatga tcgactggaa
     5641 tatcaaagaa accttggatt tgaactgcat gaaggtccaa agtcagcatt cttgttgcac
     5701 cagctttttg aatcatgttt gctactaatt tcgctgtgat tggttcccgt gcacgtgctt
     5761 tacggtcttg acgcgcatag ccataataag gcatgactac gttgattgtt tttgcacttg
     5821 ctcgtttcag tgcgtcaatc atgatcagca actccatcaa gttatcattg actgggctgc
     5881 tcgttgattg aataacatag acatgcgatc cacgaatact ttcttcaatg tttacttgaa
     5941 tttctccatc actaaattga gtaacagatg attttcctaa ctcgacgccg actgctgctg
     6001 caattttctc tgctaatggg cgattggaat ttaacgcaaa aatttttaat cttgggtcaa
     6061 agtaatgttt tgacatgggg acctccactt tctttttcac aactctagaa ttctacctaa
     6121 taaatagtag tcatattttt taaataaatc aagtgatttt gcaaaagtct tagtttagat
     6181 aagggagttt ttttgcatat ccttctttat tgacttgtct tgctctcgca attgccagcg
     6241 catattctgg aatattgtct gtaattgttg acccggcagc aatcgaactg tttttagcta
     6301 cctcgacagg tccgatgata ttcgtgctag aaccaataaa gctgtggtcg ccgacagtcg
     6361 tatgatgttt gttctttcca tcatagttga cgaagacaac accacatccg acattgattt
     6421 cttctcccag cgtagcatca ccaacataag tcaagtgacc gactttagtt cctttgccga
     6481 tttgagcatt tttcacttcc acaaagtttc cgatatggac gttttcgcca atttcagctt
     6541 ttggtcgtaa atgtgcataa ggtcccacat ctgcatgttt cttgacatgg ctgctttcaa
     6601 tgactgagtt ttcaatgacg acgtgatcct caatcctact gtctacgatt tttgaatgtg
     6661 acccgatgac acaatcagaa ccaatgactg tatttccttg gatttgtaca cctgcttcga
     6721 tcaatgtgtc tggaccgatt tctacgcctg catcgatgta tgtcgttgct gaatcgacaa
     6781 agcttacgcc attgaccata tgcatctggt taattcgctt tctcatgatc tcatttgctt
     6841 tagctaacgc gatccgatca ttgactccca ttgattcttc aaaatcatcc gtttgataag
     6901 cagcaactgt atggccttct tcttttaaga tttcgatgat atctgttaga tagtattcac
     6961 cttgagcatt gtttgttcca actttgctta acgcatcgaa caaagcttcg ttgtcaaaac
     7021 agtaagttcc tgtattgatt tcttgtacaa gagcttcttc tggtgttgca tctttttgtt
     7081 ccacgatttt ttctacgatc ccaatatggt cacggatgat tcgtccatat cctgttgggt
     7141 tttctgcttg tgccgtcaag atcgttgcac ttgcattttt tccttggtga tattcaaaaa
     7201 gattgttcag cgtttcagta gtcaataatg gtgtatcgcc actgataact aacgttgttc
     7261 ctttttttcc ttccaagaaa gaagcagctt gcaaaacagc atgtcctgtt cccaattgtt
     7321 ctgcttgtaa cgcatattta ctgcgttctc ctagttgtgc tttaacttgt tctgctccgt
     7381 gtccaacgat cgtaatcact tcatctggtt tcgtttcact gacccgatta atgatatgtt
     7441 ctaccatagg tttaccagaa acgggatgta aaactttata taattttgac ttcatgcggg
     7501 tacctttccc tgccgccaaa ataattgcat aacgtgcgtc caactgcgtc actcctaaat
     7561 atagtttgct gatttcagtt tatcccagta tacccatttt ttcaacaaaa caagtgattt
     7621 tcttttatcc cagcgttttc tggataaaaa aatagataga ccataacggg cctatctatt
     7681 tggtaaccgg tgctctcctg ccaactcctc ggtcacaagt cacactactc ataaaacatg
     7741 aaaagctgtt ttttgaaatc gtttcttgtg acttagagtt aaacggtagg cttacaacct
     7801 cttcattaaa cgtttttcaa tcagctgacc ttcggtatta gctcaataaa cggcaaaata
     7861 tgaggagcaa tttttccgtt tattgagcta atactcagga caggacgctg atttcacaac
     7921 ctctagataa acggtgttca aaagccagtt tctcggtatt aagccaaatt tatgaaaaaa
     7981 tgtggaaagc cattttcaca aaatttttct tactactcga aactaagcag ctttttcaca
     8041 acctcttatt ctgaaaaata atttcctggc acaaccgtaa tatttttcgt ttgagtatct
     8101 acatctttga cataaagcag tgacgtataa tcatcgatgg cgcgatgacc gttgaatttt
     8161 gattcggcaa atacagtgat gccaacaagt tctgattcga attcttcaat caagctcttc
     8221 attccgttga ctgttccgcc gcctttcatg aaatcatcca ctacaaggac acgtgaacca
     8281 cgtttcaaac ttctcttaga cagttccatc ttttcaattc tttcagaaga tccagacaca
     8341 tagttgacac ttactgttga tccttctgtt atttttgagt cccggcgtac aataacgaat
     8401 ggcgcattca gataatagga cacagcttgg gcaataggta cgccttttgt ggctacagtc
     8461 attacagcat cgattttttc accaaggtat ttagaagcaa tgattcttcc aacttgacgc
     8521 agcagttcag gttctcctaa caaatcagag agataaacat atcctcctgg aagcagacgg
     8581 tcttgttctg atagacgttc tgctagagat tcaatatatt ttttcgcctc ttcatatgaa
     8641 atttcaggga tgaacaatac accacctgca gcacccggga ttgtttccaa ggttccatac
     8701 cctcgttctt taaatgtttt cttgatgatt cccaaatctt cactgataga agatttagca
     8761 gattcataac gttcggcaaa gcttgttaag gaaatcaatt catgcgggtg attcaataaa
     8821 tactgtgtca tgtcaactag acgttcactg cgacgtactt tcacctattc caactccttt
     8881 taagaaattt tatcgtttta cattatataa gtttttcttc aaaaattcga gcattttatg
     8941 aaaaaataag aaaatagttc ggtatttatt aaaataaaaa gaagcctata aaaaattttt
     9001 cgtttttata aggcttcttt tctttataat ttagttattt tttcttctga aggcaaccaa
     9061 tattcgtttg atgatattta caatcaggaa caaagcaata aagactaatg tgattgttgc
     9121 tcctggaggt gtatctagat aaaacgagct agttagtcct gacagcatcc ctagaaatcc
     9181 tacacaaaca ctgatagcaa tcacgacatt gaagcttttg cctaatcgca taccgattgc
     9241 tgcgggaaga accatgattg cggatatcaa aagtgcaccg gcaatcggga tcatcacagc
     9301 aatagccaca ccagtaatca cattgaacat catcgacatc aaatgaacgg gtagcccatc
     9361 cacgtgggcg gtatcttcat caaaagtcag aacatacatc ggccgtttga ataaaaagaa
     9421 caatataccg atggcaacga ataagattcc taaaaagatg acttgctccc atgtaatggt
     9481 cacgatcgaa ccaaacagat aggattggat acttgttgct gaattccctc cgctcaaatt
     9541 catcaatact aacgctagcg ccaaaccacc agccattaaa atggcaatgg agatttctga
     9601 ataggttcgg tagatcgttc gcagatactc caatatcaca gctgctaata caacgactag
     9661 catggtcgta agtgtaggat taaggttcaa aaagaatcct aacgctaccc ctgctaaaga
     9721 gacatgagaa agcgtatcag ccatcagcga ttgtcttctg atcactaaaa acacacctag
     9781 catcggggcg attccggcaa tgaagatagc ggcaagaaac gctcttctca tgaattcata
     9841 tgaaagcaac gccattgaga atcctccttt ctcaccagtc ggatctgtct gtccgcatac
     9901 tgtttgatat cttcatgatc atgggtgatc attagaactg atttcccatg gacatgcgca
     9961 ctatgtcgga gaagacgata aaattcattt ctggattctt catccatacc tgttgttggt
    10021 tcatcaagaa caaataagtc agggtcagta gcaaaaatac gcgctaaact gattcgctgc
    10081 ttttgtccgc cagacaattc acctattcgc cgatttcgca tatcccacat ccctacagct
    10141 tctaaagcac gctgtacatg ttgatgatct ttttcagaga gacgcttgaa ccagcggcct
    10201 cttggatatc ttcctgaacg gactaattcg atcaccgtac taggaaaacc tgcattgaaa
    10261 gatgcaactt gttgaggaat ataaccgata cttaattttt ttccttcttg atttttctca
    10321 gcaatcttta tcattccttt tgaaggtttc agtaatccta acgatgcttt caccaaggtt
    10381 gacttggctg ctccattttc tccagttaaa atgacaaatt cacccgcatc tacatgataa
    10441 gagacatctt ctagtacagg ttcatcatca tagtaaaagg tcaaatcaga tatttcgata
    10501 taacgcacct tacaacctcc attctaaaac ttaattgata ctttctttta aagctttcag
    10561 atttttttcc atgacagaaa tataattttc gcctgctttg atttgttcat tagtcaagct
    10621 ttctaaagga ttcaacactt ctagcttcac tcctgtttca ttcgacaatg tctcagctac
    10681 cttcgaagag gcattttctt caaaataaat cactttgatg ttgtttttct tcacaaattc
    10741 ttttagctca gctaagcgac ttggtgtggg ttcctgatct ggtgaaacgc ccgaaatcgc
    10801 tacttgtttt aagtcgtatt gattcgctaa ataagcaaaa gcagcatgct gagtgacaaa
    10861 tgtgcggttt gttgcatctt ttagctcatc ggagtatttt tgatccagtg cttcaagctt
    10921 tttgatataa gcatcggcat tcttcgtaaa agtttccttt ttatctggat atttttcgcc
    10981 taattcttca gcaatcgttc tgacttcttt tatagctaat accggatcga gccaaacatg
    11041 tggatcgtat tcatgtgaat gaccatgccc ttcttctgat tcttcatgtt cgtctgcttc
    11101 ttgcgattct aaacggtcga ttcctttagc tgcttcgatc atcaaggtct gtttgctatc
    11161 cactgaatcc tttaacgaat ccacaaaaaa ttccatgtct gaactattat acacgaaaac
    11221 atctgcatcg gaaatttctg ctctttcttt tgcacttggt tcgaaatcat gcggctccgt
    11281 tccagcaggg atcaaaagtt tcacgtttcc ttcatcccct acgatctctt ttgtaaaatc
    11341 atacatcgga taaaaagtcg taacgatcgt caaatcctct tttttgtctg cttccttgtt
    11401 cgtatttcca catgctgcaa acagtaaagc acctatcatt accgtagctg tcaaaagata
    11461 ttttttcatt tatatgctcc tttcaatgaa caaatcggaa ttttacgatt tattaacgtg
    11521 aactaatgta tcaaaataaa aaaacacagt caatagaaat ccatcaattt ctgatttaag
    11581 catgtatatt cttgattaaa tcgtaaaatg gatgagttgc tgctcatatc tagccatttc
    11641 actacaataa aaaactgaag aataccattt taggattcct cagtttttca tcacctattt
    11701 tacttcttat attttattgc agggttcgta ctaaataaac ttcctcacaa aaacctttta
    11761 acccattata tactctctgc gctcttgaat aatgttgaca caaggcaaaa acggttggtc
    11821 cgcttccact catcaatgca gcatctgctc cgtacttgat catacgctct ttgatttgat
    11881 ggatgactgg atgccgcttt cccgttatat cttctaaact gtttcccatt tttttgatca
    11941 tctgctgata atcttgctct cggatggctt cagcaagtcc gtggatgtct tgatgttgga
    12001 tggcttgcgt atctacttct ctaaacactg tacgtgtaga gacactcatt cttggtttga
    12061 ccaacacaac ccagcactgt ggcatagaag gtaatacttg gatttcttcc cctttgccac
    12121 cgacaaatgc cgtacttccg tagacacagt aaggaacatc tgtaccgact tccaaaccga
    12181 tttctgccag ttcttctaac gaacagccca gattccataa ttggttgatc cctcttagag
    12241 cagctgcaca gtctgtactt cctccgccta atccagctgc tactggaata ttcttcttaa
    12301 caaagatctt gacaccggtt ttgatattgt atttattttt tagcaataaa gcagcttgat
    12361 aaacattgtt ccgttcatct accggtaaaa atgctttatt tgtttctaca atgattttgt
    12421 cttctgttat ttcttcaaaa aatagatgat ctgccaagtc tacgctcgac atcaccattt
    12481 ccaactcatg atacccatct tgccgtctat ataatacatc cagtcctaaa tttatcttgg
    12541 ctggcgcttt ttcaatcaat tccatcctct cacccattcg aaaagtctaa gtcgcaagta
    12601 ttctatcata gggaaaaata aaagtatagc ttatgtctgc ctagtggttg attttgtcat
    12661 cgtttcaaca gctttcacag aattttctct tcataatcca aacaagttct agtgattctt
    12721 ataattctgt gagcacttct tctgccaaac tcggaacatt tcctttttct tttcctatca
    12781 gactgagtag ctgcatggta gcaaatccga aattacttcc tttcctataa gcaaaataac
    12841 gtccttccca atgatcgaca tattttaatt tcttttcata agcagactgg aaggaataga
    12901 aaaaattacc ataattatat acgatatgca tgactttttc ttgaaagaaa gaaaaatctg
    12961 tttctccaac attagctaat ggagctaagc ctagattggc ttccgagtag cccattttct
    13021 cgtatacaat aaacagattg gctaacagat agtcagctaa ttcctcagat tctttaggta
    13081 agacccgcaa caaatcatat cccgcctgct tcttcgtcat cggctgagcg gtgatgaagc
    13141 caacgacttt ttgatcttta cggacaatac cgacaccgct agataataca tatgatttat
    13201 caaatcgtcc cacagagaag tatttttctc gtgcaccttg aagccatttt tgtgaaactt
    13261 catttacagc ttgatgtaat tcttccggca gttgatcgta ccaagtaaaa tggtatcctt
    13321 ctttcatcaa acgttgatat tcaagttgct gactcagccg agacaagtct tctgttgcta
    13381 gatcaacaat ccctgcttca cctactttcg tgaagtgaaa acccaattca tgaagcatca
    13441 ctacgtagct ttctgatatc ttataaaacg caagctgata gcctaaacaa tctgcttgtt
    13501 tcataaactg attcgttgct gcccgcatca ttttaggatt gccaactgga tctcctaaaa
    13561 caaagcattt gtttcctttg atctgataac caaaaacgac ttgatcttgg tcgtcttctt
    13621 ggtaataaaa ataactgtaa cctgacaagc gaagctgatg gcttgtagct gtgcctccgt
    13681 atgtttccaa taaacggtca aaacggtctt tttcgtactc actgccaagc ttcgtagtat
    13741 cttcagctaa atattgataa agcgccacta aagctagcaa tgagatgccc aaaccaataa
    13801 gccctgagaa ccacacatca tctgaaggaa acaaaataaa atgatttcct gttattcgac
    13861 cgactaaaaa gcgtccgctg tgatagcctg caattgcgta aacgataaac aaaaagccga
    13921 acaagctagc atcaaagatt atagctcccc aagaataaac gaattttgtt cgataaaatt
    13981 cttttctgga taaccacaca gctaacagaa tcaagacata taccaatatc aactgccaag
    14041 ataacgtacg tgtgattgta tttaaaatac caaaagatag taaagcaatc gtaggcagaa
    14101 atgccttttt gacttttact gaaagtgctc tagcaaggcc gagtaataaa aagccaacca
    14161 atagattcac tgtctgatct aaaaaattga atgagaacgg caataatact tgaaatagcc
    14221 gactgattgc agacagatta gtgattgttg atagaagtac catcatgatc cccgcaaaat
    14281 agacagcact tacgagcacg atatgcgcaa ccttttggaa aaacagtcgc ggaatgttat
    14341 ctaaaaatcg attgattttg actcctgtat gtgtgatgaa caatagaagt cccgtcataa
    14401 aaggtagaac ataataaaac aaccgataat ataatagcca aactactgct acatcttgcc
    14461 gaacaggcaa ttgactcatt cctaagatca tcaaaacgtc aaaagtcccc attccacctg
    14521 ggaccatcgt cagcattcct atcaatgtag caatcatgaa cataggatag atcgaaagca
    14581 tcgaaatatc tattctcatc aacttgccga tgatcaaaaa taccgcaagg gctcccgtcc
    14641 attgtccaaa ggatgccagt agcagaccaa gcaagccttt tggataaaac tcgaagaaca
    14701 atgtctttct ctttagataa gcaaaaaaga aaatgactgg tgctaaaaaa ctaccgccga
    14761 aaagccagat ccaatagctt cgaaaaatac tttctgactg aataaaaaag acatcaataa
    14821 atgtaagaaa cgaccataca gacaaaccag tcagcataaa tagtgcgact tttgatacag
    14881 tggctaaaac catttttcta tttgtctgct ttccataaaa actagcccgc agacttgctc
    14941 ctaccacacc accaaaaccg gcgagattgt tgatcgtgtt tgttacccac gcagcaagaa
    15001 gaaactcttt tctttccatt tttggttttc cttgtttttc taagactctg atcgtcaccc
    15061 aatcatacaa caacatcgga gtgacaccca gcagtccagc cagaatcatg agcaggatcg
    15121 tcatgcggct ttgttgtccc atcctttgcc aaatatcttg ccaactcatg ccattagcaa
    15181 tatttgcgac ttgatttgcc acaaagacta acacggagcc gaaaaaaatc agttttaaaa
    15241 tcagactatg ttcctttatc cattgcagca tcaagtatcg tttatttttc acattttccc
    15301 attcctaact tgtatacttt tgtgtcatac cccaatgtta tcttatttat tttaattttt
    15361 ccactttaga cctgttcttt gcttgcgatg atagaaaaag aaagatatcc taatgctaaa
    15421 ggagaggata acatgaaagt aggatttatc ggcacaggga atatggcaca agctattatt
    15481 gatggtttat taaaaaaagg aacagtctcg aaagaagagg tgttcgtttc cagtggacat
    15541 tttgaaaatg cacaaaaatt tgctgctgaa actggcgtcc atgcatgcaa aagtaatcag
    15601 gaagttgcat cacaatcaga tatcgttctt ttagccgtga aaccaaaaat cattgaaaaa
    15661 gtattggaag aactaagaga atatagccag aaagtcttat tcatttctat tgcttcagga
    15721 aaatcattaa cagatttaga aacagcgctt gaagatcctc aggcctccat cgtacgtgtg
    15781 atgccgaatg tcaatgtcag cgtaggagca ggcgtttctg cgatttgcaa aaatgaagct
    15841 gccacggagg aacagcttca gcaagctacg atgatttttg aagcaatcgg cagcgtctat
    15901 cctttagcag aatcagattt cagtacattc attggccttg ctggcagctc acccgcattc
    15961 gtttacatgc tgatcgatgc gatgggacgg actggtgtac tgaatggttt gtccaaacag
    16021 acagccactg agattgctgc aaaagcaatt atgggttctt gtcaaaaatt cctttcaagt
    16081 gataaaaatc catgggaact tgtagaccaa gtttcttctc ctggcggtac aactgttgca
    16141 ggtgtagttg ccttagaaga agcaggattc atcccagcaa tcatcaaagg aatcaatacg
    16201 acgatcgaga aagatcttga gatgttgaat aaaaaataat gatagcaatg ttttttcgtg
    16261 ccttacaaaa aaagaagagc tgtggctttt gccgcggctc ttcttttgta ttttttatta
    16321 tttagcataa tcagttgcac gagtttcccg aataacgatt actttgatgt gtccaggata
    16381 atccagttct tcttcgattc gtttacgaat atcacgtact aaacgaacag cgtctaaatc
    16441 cgagatttct tctggcttga ccattacccg aacttcgcgt ccagcttgaa ctgcgtaact
    16501 tgattctaca ccggcgaagc tgttcgaaat attttccaga cttcttaaac gacggatgta
    16561 gttttctaat gattcacttc gcgcaccagg tcttgctgct gagagcgcat ctgctgcagc
    16621 tacaaggaca gagataacag aagtagcttc cacatctcca tgatgagaag cgatcgcgtt
    16681 gattactact gggttttctt tgtacttggc agctaattcc gcaccgatct caacgtgaga
    16741 tccttcaatc tcatggtcaa gtgctttccc aatatcatgg agcaacccgg cacgttttgc
    16801 taattggata tcttcgccaa gctctgctgc taagatacca gctaattttg caacctcgac
    16861 cgaatgcttc aagacgtttt gtccataact agttctgaat cgcagacgtc cgatgatctt
    16921 gattagatct ggatgaagtg tatgagcacc gacttcaaac gctgcctctt ccccgtattc
    16981 gcgaatacgt tcatccattt ctttacgaga tttctcgacc atttcttcga tacgcgctgg
    17041 atggattcgt ccatcttgta tcagtttttc caaggtcatc cgtgcgattt ctcttcggat
    17101 tggatcgaat ccggaaagaa caactgcttc cggtgtatca tcgatgatta aatcgatacc
    17161 agtcagcgtc tcaagcgttc gaatattacg accttctcgt ccaatgatac gacctttcat
    17221 ttcatcattc ggaagggtaa cgactgaaac agtcgtttct gaaacttgat ctgctgcgca
    17281 gcgttgaatc gctaatgata ataagttttt cgctttgcga tctgcttctt ctttggcacg
    17341 ctgttcagat tcttttacca ttagagttaa ctcatgattc agctcttctt cagtcgattt
    17401 catgatgaca tctcgtgcgt cctcttttga taaaccagca attttttcta gttctttttg
    17461 ttgatcttca atcatttttt caacgtcttt ttctcgctct tcaattaatt gctgttttga
    17521 actaagtgct tcttctttac tttcaagtga gttctcgcgt ttttctaacg agtcatcttt
    17581 acgattcagc gtttgttcgc gttgaatcaa acgattctct tgagatttta attctaactt
    17641 actttctctc agctcacttt caacttcaga acggtatttc tgattttctt ccttagcttc
    17701 taacaatgct tcttttttta gagtttctgc ttcttttttt gcactatcga tgattccagc
    17761 agctgatgat tgtgcaccag ctatttcttt ctcgtgacgt gactttgcga ccataaaccc
    17821 taaaccaaga ccgacaatta aaccgatgat agcgaggaga atgttgaata ccataaaatc
    17881 cacctccata ctatcttttt catttttatc atctatacag cttctatgat aaattattct
    17941 aaactcgtca atatgcatct tcgcatatat gtgtacaaaa aacatgcaca actttattct
    18001 aatgtttgta ccccgtagtg tcaactttaa ataaacaaag aaacggcttt ctacttattc
    18061 attaaacgat ggtttttaaa ataaatgaca ctagtttcat ataggtaaac ctttaaat
//
LOCUS       DAZUJR010000062        16928 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.062, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000062 DAZUJR010000000
VERSION     DAZUJR010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16928)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16928)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16928
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.062"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(251..2143)
                     /locus_tag="ACG804_002001"
     CDS             complement(251..2143)
                     /locus_tag="ACG804_002001"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4832925.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(2140..3867)
                     /locus_tag="ACG804_002002"
     CDS             complement(2140..3867)
                     /locus_tag="ACG804_002002"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4832926.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(3883..4533)
                     /locus_tag="ACG804_002003"
     CDS             complement(3883..4533)
                     /locus_tag="ACG804_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HFS4832927.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            4737..5033
                     /locus_tag="ACG804_002004"
     CDS             4737..5033
                     /locus_tag="ACG804_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFS4832928.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            5205..5825
                     /locus_tag="ACG804_002005"
     CDS             5205..5825
                     /locus_tag="ACG804_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFS4832929.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(5917..7083)
                     /locus_tag="ACG804_002006"
     CDS             complement(5917..7083)
                     /locus_tag="ACG804_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFS4832930.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(7095..7448)
                     /locus_tag="ACG804_002007"
     CDS             complement(7095..7448)
                     /locus_tag="ACG804_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HFS4832931.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLETVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            7576..8598
                     /locus_tag="ACG804_002008"
     CDS             7576..8598
                     /locus_tag="ACG804_002008"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HFS4832932.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            8617..8778
                     /locus_tag="ACG804_002009"
     CDS             8617..8778
                     /locus_tag="ACG804_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832933.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(9037..9471)
                     /locus_tag="ACG804_002010"
     CDS             complement(9037..9471)
                     /locus_tag="ACG804_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832934.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLKKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(9581..11440)
                     /locus_tag="ACG804_002011"
     CDS             complement(9581..11440)
                     /locus_tag="ACG804_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFS4832935.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            11441..11581
                     /locus_tag="ACG804_002012"
     CDS             11441..11581
                     /locus_tag="ACG804_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoglycerate dehydrogenase"
                     /protein_id="HFS4832936.1"
                     /translation="MLAPSFLSIKECCFSYFSCTKFESKERKEELMKSKYSLSLWPFW
                     FL"
     gene            complement(11558..12718)
                     /locus_tag="ACG804_002013"
     CDS             complement(11558..12718)
                     /locus_tag="ACG804_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFS4832937.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(13025..13936)
                     /locus_tag="ACG804_002014"
                     /pseudo
     CDS             complement(13025..13936)
                     /locus_tag="ACG804_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
     gene            complement(14102..15295)
                     /locus_tag="ACG804_002015"
     CDS             complement(14102..15295)
                     /locus_tag="ACG804_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4832938.1"
                     /translation="MSEKRRDSKNRVLRSGESQRKDGRYAYKYVDTFGKPQFVYSWKL
                     VPTDKTPAGKREDISLREKEKEIQKDLDDGIDTIGKKMTVCQLYAKQIRHRGNVKHNT
                     KLGRERLMRILEQDRLGSCPIDSVKLSDAKEWALRMKEKGLSYKTINNDKRSLKAAFY
                     TAIQDDCIRKNPFDFQLSDVLDDDTEPKVPLTPAQEESFLSFIQGDKVYQKHYDAIVI
                     LLGTGLRISELCGLTDKDLDFENRVIIVSHQLLRNTGVGYYIDEPKTQSGVRKIPMNE
                     EVYQAFQRVIKNRKGAKPFIIDGYANFLFLKQNGYPMTAVDYGGMFGRLVKKYNKSHE
                     EALPKTTTPHAMRHTFCTRLANAGMNPKALQYIMGHSNITMTLNYYAHATFDSARAEM
                     ERLAA"
     gene            complement(15379..15579)
                     /locus_tag="ACG804_002016"
     CDS             complement(15379..15579)
                     /locus_tag="ACG804_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HFS4832939.1"
                     /translation="MNHDVPIWEKYTLTIEEASKYFRIGENKLRKLAEENPASGWVIM
                     NGNRIQIKRKQFEKIIDTLDTI"
     gene            complement(16003..16236)
                     /locus_tag="ACG804_002017"
     CDS             complement(16003..16236)
                     /locus_tag="ACG804_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4832940.1"
                     /translation="MKNPNYKGIELLPLSVIEAARAGDAGAVERVLQYYSGYMNKLCT
                     RTLYDENGYPHVCLDEAMKRRLEIKLIHAIVTN"
     gene            complement(16243..16674)
                     /locus_tag="ACG804_002018"
     CDS             complement(16243..16674)
                     /locus_tag="ACG804_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFS4832941.1"
                     /translation="MDAIPRDYEARCMFDAFCKTVLRNEAKSYLAEMKRRRDREVSLS
                     SLSQADLDKLCTVDHYPSDSFTFSSHGYDLHINNELVAEAFAALPSMEQSILILHCVL
                     DMADGEIGGLVGMSRSAVQRHRTNTLSELRKQLKALMPKGG"
BASE COUNT         4752 a         3698 c         3178 g         5300 t
ORIGIN      
        1 tcctattttt cgtttggttg ggcttattac cgcagatgca agcttttgaa caccgtttaa
       61 ggaagaggtt gtaaaatcag cggtttgacc tgagtattag agatacaaaa cggaaaaata
      121 gcttctcata ttttgccgtt ttttgagcta ataccgaagg acagctgatt gaacaccgtt
      181 tattcggaaa aagggactgt gacacgactt ttgtcacagc ccctaaaaaa aataataaat
      241 ttgtactatt ctatgaagct tcttcttcag aaaactgact gttataaaga tctgcataga
      301 atccgtcttt ttccatcaat gtatcgtggt ttcctgtttc tacgatcgaa ccatgattca
      361 tcacaataat gttgtctgca tcgcgtattg tagacaagcg gtgagcaaca acgaaacttg
      421 tccggttttc caataggcgg ttcatcgctt tttgaatcag tatttctgtt cgtgtatcta
      481 cactagatgt tgcttcatca aggatcagga catctggatt tgctaagaat gcccgcgcaa
      541 ttgtgattag ctgacgctgc ccttgcgaaa tattgcttgc atcctcgttt aatacagtgt
      601 tatatccttc tggcaattta cgaacaaaat cgtctacgtg agcagcttta gcagcctcaa
      661 tgatttgttc gtctgttgca tcgtcgttcc catatttgat attgtcatag atacttcctg
      721 taaacagcca agtatcttgc agtaccattg aaaactgtgc gcgcaattca tcacgtgaaa
      781 gatcacgggt atctacacca tcgtaacgaa tactacctcc agaaacatcg tagaaccgtt
      841 caagaaggtt gatcagtgtc gtcttccctg caccagtcgg acctacaata gcgaccatct
      901 caccaggttt gacatccaag ttaaaatcag tcattagcaa gttatctggt gtgtagccga
      961 attgaacatt ttcaaaacga actttgtatg gtgtatcttt ttcttctgga aggccagatt
     1021 tttcattgga catctcttct tcatccaaca cttcaaatac ccgttcggct gaagcaactg
     1081 ttgattggat agtgttcatc aaacttgcaa gttgagtgat tggttgagag aactgtgttg
     1141 tatattgcaa gaacgcttga acatccccta atgtcatgtt cccatttgca acttttactc
     1201 cgcctagtac agcgacgaac acatagccta gatttttaac gaaattcatc aacggcatga
     1261 tgattgccga aataaattga gctttccaac cagcggcata cagattctga ttttcttttt
     1321 caaatacttc ctggtctttt tcagtatgat tgaatgtttt aacaatggta tgaccaccat
     1381 atgtttcttc tacttggtta ttcaataaac ctaaactttt ttgctgatct gcgaaaaaca
     1441 cttgtgattt cggcgctacg atcatcacga tgatcaagct taaagggatc atcaataacg
     1501 cgactaacgt caattgccag ctgattgaaa gcatcatcac gatgacccca atcaatgtga
     1561 ctgcactagt tacaaattga gtcaaatttt gctgcagcgt gcttgcgatg ttatccatat
     1621 cattgattgc tcgagacatg atatccccat ttgtatgtgt atcataatag gaaatcggta
     1681 cacgattcat tttggcttcc aaatcatgac gtaattcata aactgttcgt tgggaaacac
     1741 gtgtcataat aaattgctgt aaaaagttga atacagcaga aatcaaatac atcacgatta
     1801 ctgtcgcaat gatctgcgcg attttatcaa agtctatcgg aaattttgtt acttgttggc
     1861 cttgttgcat ctgttgagcg ccagccatta cacctttgaa tatttctgtg gttgctttcc
     1921 ccaagacctt tggtgtttgg atttggaaga tcacggctgc tattgctagt acaaatacag
     1981 cgatgatcgc aaccatacgt ttagacatat agccaaacaa tcggcgtacc gttccccaga
     2041 aatttttagg cttttcacct tttacaccga gatttctgcc aggtccacca tgtcctggac
     2101 cgcctgctgg tccatgagag ggacgtgtgt ttgttttact catgctaagt cctcctctct
     2161 tagttgtgaa tgaacgattt cttgataagt ttcgtttgtt gctaatagtt cttcatgtgt
     2221 tcctttgcca accagttttc cttcatctag cacaaggatc atatctgcat ccattactgt
     2281 acttactcgt tgagcaacta aaacggtgat actttctttc atattcgttt tcaatgcttg
     2341 gcgaagattg gcatccgttt tgaaatccaa cgctgagaag gaatcatcaa acacatagat
     2401 atctgctgtt ttgactaatg cccgtgcaat tgccagacgc tgtctttgtc caccagagaa
     2461 gtttcctcct ccttgttcca catggctatc taagccatct tccatctctg aaacaaaatc
     2521 tttagcttgt gcgatttcta atgctttcca aatcatttca tctgttgcat ccggcttacc
     2581 atactgcata ttgtctcgga tcgttccaga gaacagaact gctttttgag gaacaaagcc
     2641 cattaattct cgcaaattat attgagtcat gtcactaatg tccgttccat ttatttggat
     2701 cgaaccagat tcgatgtcat ataatcgagg gatcaaattg actaaggtcg ttttacctga
     2761 accagtcccc cctatgattg cgacgatctc gcccgacttg gcttggaaat caatatcttc
     2821 caatgcaagt ttttctgctc catgatatcg ataattgaca tgattgaagg ccaatgttgc
     2881 gttttttcca gcaaaagaaa ctgttttagg attttcaggg tcatggatac cgattttttc
     2941 atccaacact tcattaatac ggtcagctga agcttgtgca cgaggcacca tgataaaaat
     3001 agcggaaagc atcataaagc tgatcaagat ctgcatcgca taagtcataa atgcaatcag
     3061 attaccgact tccaaagtca tatctgctat gtagtgtcca ccaaaccaag tgattgctac
     3121 gtttgtaccg ctcatgatca atgtcatcat tggcatcatc aatgcgacga tcgtattaac
     3181 tttgattgcc gtatttgtat aatctttatt cgctaaatca aaacgatttt cttcaaagcg
     3241 tgtcttatcg aatgctcgaa tcactctgac ccctgtcaat ccttctcgaa ataccaggtt
     3301 taaacggtca gttttctttt gcatactttt gaataatgga acagcaaagt acatgattcc
     3361 gccgatcaaa ataatcatta ctgggatgac aactaagaag atttttgtca actgatgatc
     3421 tttttgataa gcaagtatgc tcgcgccaat caacgtgatt ggtgcattga tcatcatacg
     3481 taaaaacatt tgtgtaacca tttggatttg agtcacatca ttggtcgttc ttgtgatcaa
     3541 agaggccgtt ccatatttat caaacgcatc ttttgtcaga ctctctgatt ttttatagac
     3601 atccgtacgc aattgcttac ccagtttctg tgattcacga gtagcaaaaa atgtatttgc
     3661 gatagcagct aagatactga tcaaagaaaa gccgatcatc acaaaacctg tatgccaaat
     3721 ataatcgaca tctccttgcg ctaccccttt atcaataata ttggaggtaa gtgtcggcaa
     3781 atataaatct gccagtactt ggatcaccat gaaaactgca gctgcaattg ctgaagtcaa
     3841 ggagatccgt tttacgattt ttagcatcta gttcccttct ttctatttat atactccgtt
     3901 tttcagccaa gaaagtttca aattgaattc actgattgct tgctctactg agtaatcttc
     3961 agatgttgaa aataagcgat acgaatgcgc aattgttgta aatacagtat tcatcactaa
     4021 ttggatcagt aattccaatt catgatcatt ttttactttc agcttcgtcc gatcgatcaa
     4081 ttcaagcaac tcttttgcat cttgtttgtg ttctttatgt ggatcgtgag gcgttttttg
     4141 gcgactcgta tgaggagcga cttttcttga ggcacggtaa tccatgttca taaacaagtt
     4201 acgataaaaa gaagcattct cgccttccaa aatctcataa atcattttag aaaaatagga
     4261 ttcgaatcct ttgaatagat caccatcgga ttctttcatt agttgtaaca tatctttaga
     4321 gctgtcacgt ctcattgtct caaagtaata aaaataaaga tcctctttat cttcaaaata
     4381 ctgatagaaa ctgcctctag ggatatccgc taatttgacg atattagcaa tcgaagcttc
     4441 ttttaagggt actctagaaa actcgattct cgcagcctcg attagtcttt tttgtttttc
     4501 tttaggcaaa tggaaaaatg tctgtgtcgg catatggatc ctcctttctt tcaagatgac
     4561 acattgtcat atgacgctgt gtcattataa cacctcctac ctgttttgca agacatttgc
     4621 atagtttttt tcattatcat ccgatacatt aaaaaagtga taagaggaat ccttccattt
     4681 gaattaatga gagttgccca ttaaaatagc cacatactaa acaaaggatg agataaatgg
     4741 cccaatcaat tagtgtccaa gacttcaata aattgcctct cgatgctgac agcatcgttt
     4801 tagatacaag aaatacctta gattacacaa aaaaccactt aagccactcg ctttctatcc
     4861 ccgctgctat cttgccaaga caattaaaaa atctagatcc aaagaaactt tattatattc
     4921 taagctatac aggcaggcga tcagaagcat tagccgatca acttactgct aatggttttc
     4981 gtgctgttta tatcattggt gggatggaag ctcttcagtc gagtgttgct tgaatattgc
     5041 ttgttagatt caaaagaggc tgtgacaaaa aatcgtgtca cagcctcttt tataccctgt
     5101 ctttttttag ttatttattc ttcaacctta tcaatatgac ttgatagcct tttctttttc
     5161 tcatagttat aacaatcata gcaataaaag gagaaggtaa gcatatggca tctgttttag
     5221 tagtcaaagg tcatccccta actgcagaag aatcgcgcac agttaaggca ttgacgtctt
     5281 ttttaacaag ttataaagaa aatcatccag atgatgaagt gactgttttg gaactttatc
     5341 gcgatgatat tccggaaatc gatgaagaat tattatcagg ttgggaagca ttacgtgctg
     5401 gtgcagaatt cacttcctta tcagaaagtc aacaacaaaa aattgctcgt ttcaatgaat
     5461 tgactgatca gttccttgct gctgataaaa tcgttatcgc aaacgcctta tggaatctaa
     5521 atatcccaac aaaattaaaa gcttggttcg ataccgtcaa tgtagctgga aaaacgttcc
     5581 gctatacaga aaacgggcca gaaggattag tgacaggtaa aaaagcactg cacatccaat
     5641 ctaatggcgg tgtatacaac ggacaagact ttgcctctca atatgtaaaa ggtattttaa
     5701 actttgtagg catcgatcaa gtagatcagc tattcatcga aggaatcgat tatgaccctg
     5761 accgtgcaga tgagttgatg caaaatgcat tagataaagc tgctgcttta ggtaaatcat
     5821 tttaaaaatt gagataaatg catacaaaag agacagagga aaaaatcttc aaagcagcat
     5881 ttgtaccttg gatattttcc catctgtctc tttttgttat tctttctgct ttttcaacgg
     5941 attttcttca taaagagaag agattgttgt gtaccattca aaaacatgag taatcactac
     6001 tttagctgct gcataaacag gaatccccaa gatcacaccg atgattccga acaatttccc
     6061 agaagtcagc agaactaata aaatcgttac tggatggatt gctaactgat tccctagtac
     6121 taatggagag atcaagcgtc cttctattgt ctgctctact gcaaaaacga tcagtacttt
     6181 gatgatcatg aatggacctg ctacaatggc taaaaagata gccggaatca tcgctaaaaa
     6241 tgatcctaag taagggatca ggttcaaaaa acccgcaata atccccaacg tgacagcata
     6301 ctctaaacca atgaccgcaa aaccaatcat aaacatgatt gccacagcaa aagccacagt
     6361 tagttgtcct cttatataag aagaaacttg actattcatt tcactcagca cattcaacgt
     6421 cggtttttgc atgcgtgtcg gtaaaaattt gacaaaataa ggtgctaatt gtttaccgtc
     6481 tttcaataga taaaataaga taaacggcat cgtcagcaga gccactaaaa tagtcgctac
     6541 cgcgccgaca aaacttccaa gactctgaac tgtactctta gatatatctt ggatcatatc
     6601 gcctgccgaa ttcatgaact tatcacctgc tgtttccaac tgttcgcgaa attggttgaa
     6661 cagcgggtcc cgcaaaatct cggttaattt attatcaatc gtatctacat attgagggaa
     6721 gttactgatg aagctcactg tttgttcctg aatcttaggg atgatcacta cgctccccca
     6781 tgcgattagt gcaacaacca aaacaaacag cccaatgata ctgtaaagcc ttggtacttt
     6841 tcgcttttca aagtaatcaa ctaccggatt catcaagtaa tacaagattc ctgctaaaat
     6901 gataggcaga cctacgattg ctaaaaattg ccagattggt gcaaacaaat atgaaacttt
     6961 tgtaaataaa aagacgatca gcaatattaa caatacaaca agtaaggctg tgactacttg
     7021 attatttaaa aaccagcgcc aaaaccacga taccggtctg ttcttcttat tttttccttc
     7081 cataattcct cctgttagtt ataaaaaatt tggcttccca aaccaatagc aggcagtcta
     7141 tgcggatgaa gatagattcc atttgcaatt tgtccttctt ctggacaagc atcaaaaatc
     7201 aatgatacgt gagctactgt ctctaaattc ccattggcca tcggaccgac ataatcgatc
     7261 gtatatacct gatcatcaaa agcaattgtt ccgcctgctt tcaaagaaaa aggttcgtct
     7321 tttgatactt cttgaatcac cgaatatttt cgtaaggcag ctgttgctgt tttatcgaac
     7381 aaaatcagca tgggttcttc cttgtttatt gcttctgtcc caatttctgt aatctttgcc
     7441 tgaatcattg cactctctcc tttaattgct ttcaaaaaca gtataacaca ttctcattct
     7501 ttagccgtgt ggaataatta tgtgatagaa taaaaacgaa aactatttca ttacaattag
     7561 gaggaatcag ctcatatgat cgaaaagata attttaggaa cctatacgcg tcgcgaaagt
     7621 aaaggaatct atacgatcga ccttgataca gaaaaagaag aattagccaa cctttcatta
     7681 gctgttgaag aaaatagccc tacctatgta gcaaaaagta aagctggcaa tctttacaca
     7741 gttactagtg tggatggatt aggtggtgcc ggtgcgtacg ataaggattt tcattttttg
     7801 aatgcggtaa cagagtctgg cgctcctttg tgttatgtag cggttgatga agcacgtcaa
     7861 ttactatacg gggcgaacta tcataaaggt gaagtaaatg tctaccatat attaggagat
     7921 ggcgaactga aagcagcaga ttcaatattc catcaagaag cgacaggtcc tcataaaaac
     7981 caagatcatg cgcatgtcca ctatacggat ctgactcctg accaacgatt agtcgtatgt
     8041 gatcttggta cagatcgtgt gtatacttat gatgtgtccg aaaacggcaa attgaatctt
     8101 gtaactacct tcactgcaga gccaggaaca ggccctcgcc atcttgtctt tcatccaaat
     8161 ggacaattcg cttatttatt tggtgaatta gacagcacag tccgcgtgct ttcttataat
     8221 aaagaaacag gtgcttttga agaattacag aaaatatcga ccttgccaga agaattcgac
     8281 ggtgaaaatg gaggggcagc tatccgcatt tcaaatgatg gcaagttcct ttatgcttct
     8341 aaccgaggac ataactcgat tgctgtattc gcagtttttg aagatggttc ccacattcaa
     8401 aacaagcaaa tcatctcaac agaaggggat tttccccgcg atttcgcact agatccaagc
     8461 aataattttg tcgtgtgtgc caatcagaac accgataatc tgacattata tcgccgtcat
     8521 cctgaaacag gattactgga attactgaaa aaagatgtct atgtaccaga atgtgtctgt
     8581 gtttattttg atcgttagta agaaaaggag aatgaaatga atcagcaaga cgtattagac
     8641 agactacggg aagaactaaa tattcctttc tttgatggga aaatcgaaga taaagagtat
     8701 agcgaagagg aatatcagaa actcaaagcc gatttacaga actactttga acaatatgta
     8761 cagaatgtag aaaactaatc agctttccat actatctgaa aagaacatca ggacaagact
     8821 tttccgtcta tcctgatgtt cttttctaca aataaaaaac cgccgagatg gttagactcg
     8881 acggaaaagg agtatttact cgattttgag taagtacaag gttgttgttg gttataggta
     8941 tgtcattatc ataaaggatt ttgatcactc tatcataaag gtaatattac atttatatta
     9001 gataactcta gtttttattg ttatcaaaga tttcttttat tttttcaaca acaaattagt
     9061 cattttttgg atggcagctg tcaattggtc tgtcgcttgg tcttgttttg cttcagatgt
     9121 attgaataga tcttcatcta cccctgattc aagatcgata ctttggatca tttcttcaca
     9181 gcctgctaca tatgaaagat aagctttttc aaaattttta tgaatgccca ttgcttttgc
     9241 tggtggacgc aaagtactga ctttcttaag cattgcccga tatttttttg ttccttcttc
     9301 aaataacagg atgatctctt caagagtcga tttgtccagt tcacttgttt ttccttcatc
     9361 aattgcgttt ctgatcactt catatttcgg atgcattcct tctccgattg cttctgtttc
     9421 cttgacgatt tgatcgatgg actgcacata atagccaata ttcggtaaca tgttcgtttt
     9481 cctactttct ccattgttgt tattatttat tctacttgtt tttatcctca aatgacaagt
     9541 acttgaaaaa atttaatggt ttctatacag ctcgccattc ttattcgtgc tcaaagaaac
     9601 catctgctaa actatattgt ttccctgcga caatgtcata ttggatcaat tgatattcgt
     9661 cgtaaatctc ttgttgcgag cgattgaatt gcgcttcttt ataccactgt ccgttttgat
     9721 agtacagttc tcgttcaaac gccggaagtt cctgttctaa tgataaaagc agctgataaa
     9781 agccatttgt tgtctgattc gtctgttcca ttagattcgc tgcaaaataa aacggactgg
     9841 tgattgcatc gtgagtcgtt tgcttttcta attctccttt actgtcgaac ataagaaatt
     9901 gtgtttcatg caatgtttgt ttgtcatttt ttgcttggat cgtatctgaa tagatccctg
     9961 gaagatgatc cccccaaaaa acaactaaag tccttctaga aagattcttc aattcttccg
    10021 tgaactgctt cagtgccgtg ctgctatagg aaatatcttg cagataattc tctaagtcaa
    10081 gtgtcccact tccatctgaa gtttttgcag gatagtctag attatcatac tttccatcgt
    10141 agggcatatg tgtctgcatc gtgactaaat gaatgaactg aggtgttttt tcttccttga
    10201 gaagtgtcat tacttctttg taagctgact catcagaaat atatggatta ttctctatcg
    10261 tatccgtata ggtcatcgta cgctcgctga tgaactggtc aaatcctaat gtctgataaa
    10321 catcctctct tttatacatc gaagtattgt atggatggat cgctgtcgtc tggtatgatt
    10381 gtgcgtttaa cgctgaaacg atagaaggaa gctgatccat ttttggtaca agcatcgtgt
    10441 aaggggtggt gagttgcgca ttaaataacg ccatagaaaa accagtcaat gcttcaaatt
    10501 cgatatttgc tgttccaccg ccatagtttt gagaaagcat attgccacta tatgtttgat
    10561 cagctacttc ataataatct gccaatggct caccagatac ttctacgccg tttaatcgac
    10621 taggatctga gaaactttca ctcatcacga acacgatgtt cggcgactct tcctctacag
    10681 ttttattttt ttcatcggct agcttctggt atttttcagt gatttctttg atcttttctt
    10741 tcgaatatcc ttcaggttca tccattggtt ctaccttcag attgtacaaa aacccaccga
    10801 taaaaccagt gttatagtag ttcattttct ggctgtaagg tatccatagt gccgttttat
    10861 tatatgcttt tcgcaacaaa ttatcgggat tgttgaaatt actgatatac cctagcagtc
    10921 caattgccac aagcagtgtc gttaatcgga tcaattggaa tcgccttcct tttttcaggc
    10981 ttcgaaacat gtaccagcaa aacaatccta tcacggttcc tgcggcagct aagatcactg
    11041 taaacagcat agtgccggtc atatctttca gcaatccgat ttcagtgatc atcttcaaat
    11101 cgtctggata aatcggttct tgccgataac tcattttcat ataatttgca aaacctaata
    11161 caccgatggc tacgacatac gtaagggaac ctaaagggac agatcctgct agtgcaatca
    11221 gaaaaataag aataatcagc aagacgagac aggctaagaa gaatttttcc gtatgccaag
    11281 aaaaagcaaa tttcaacgca aggtctacgg atagatcatt ttgacaccac tgcaaaaata
    11341 aattactaaa aacaacaaga aaaaagatac tgatgattgc tgctgttcct tttaaaatct
    11401 ttttctgttt ggtcgaaagt ctgcttatat atcttttcaa atgcttgctc cttcatttct
    11461 atcaataaaa gaatgttgct tctcttattt tagttgtacg aaattcgaaa gtaaagaacg
    11521 gaaagaagaa ttaatgaaat ccaaatattc tctttcttta tggcctttct ggtttcttta
    11581 ataagcggac ctttcgtact ccagaaattt tttctagctg ttgtttcact tgattgagct
    11641 gttcaaaatc agtactgtct atgtcaatca atatgtagac atgctcattc ttatggttac
    11701 gcgatatatc tgcgatcgct agctcgttct cattcagcag agaaaatatc tctgctaata
    11761 tattggtttt cttttgataa aatatagtga atcgaaacgg cgcttggaaa aacattcgtg
    11821 cggatggata attgaccgct tctctaaccg taccgaacaa aagataatct tttaaggctt
    11881 caactgccaa acgtccgctg tctgccaaag cttcctgagt cgatccccct agatgaggca
    11941 acataagtat acggtcattt tctaagaact cttcttctgg aaaatcagtc aagtatttag
    12001 ccagatgttg tttttccaat gcttgcataa cagcatattt atcaacaatt tcacttcttc
    12061 ctacattgat aagtacagca tcttttttca ttttttctat attcgcctga tcgatcaatc
    12121 cttttgtatc ttctgtcaac ggcagcatga ctacgatgta atccgaggta gaaagaactg
    12181 tttctaaatc tgcttgccga acataatcca actgggcatc gcggatagaa taacccaaga
    12241 catccatccc taagctatag caacttagcg ctacttttgt gcctatcgct ccaagaccaa
    12301 gaagaccgat ggttttgcct tgcaattctc gtcccacata agcacttctt ttgttttctg
    12361 cctgttctaa aatattagga cctgttagtg tttgtaccat acgacttgct tcgattatcg
    12421 gacgggaaga taagagcaaa cagcacaaaa caagctcttt tactgcatta gcatttacac
    12481 ctggtgtatt catgacgatc gtcccgtttt cagaagcttt ttcaacgttg atcgtgttca
    12541 ccccaacacc agctcttgaa attgctagca aatctggtgt aagccattca tctttcactt
    12601 tcgtactacg aataactatt ccttcggctg gcaaatcatc tattattttg aaatattccc
    12661 cttgtaactt ttctatctct tgttctggaa tagcatcaat caaatgaacg tgatacataa
    12721 aaccccctcc ttactaacaa gtatctcgaa atttctgcaa ttagacaact gtttaccatt
    12781 tgacttccta gaagcaaaaa gagcagttag agcagagtag gctgagtgat aaaaataagg
    12841 ctatgacaag ttactgccat aagccttatt ttcgagagca aaatattgag ggtgagatat
    12901 cttgataaat ggtgttccgt tagctgacat tgataataag actaaatttc aaaaaagttg
    12961 aaaagcaaat ttcgtcaatc tcttcttatt tcttaaaact aagtggcttt ttcacaacct
    13021 ctttttatct aataaccact gtttccaact caactaattt tgcccacgtt tcaatttgat
    13081 ctgttgttag atttagcgag acaacggtat gatgaccgcc acctgcctga atccatgaat
    13141 ggacaccttc atggaaattc ggtttagttt tccataacac acgtgcaaca ggtaaattag
    13201 gtgcttcagt cgttggttca aaggcttcta cttcattgat cagcagttta taatgcgtac
    13261 cgaaatctgc catcgatacg actacccctt ctcctgcttt cccatcaaat acaagacgcg
    13321 ccggatcttc tctatctccc attgataaag gagaaacaac gattcttggt ttcgtcgcag
    13381 caagcgtcgg atctacttcc atcatatggg attccaagat tgcttcttgg ccactagcta
    13441 gctcgtaagt ataatcttcc atgaatcctg tatctttccc tcgagccatg attttcagca
    13501 accgatcaat cgctgcagtt ttccagtcgc cttccccagc aaaaccgtat ccttctgcca
    13561 tcaaacgttg tacagctagt ccaggtagtt gtttcattcc atacaggtct tcaaaattag
    13621 tcgtaaaagc gttatagcct ccttcttcta agaaacggcg aataccgatt tcctgctgag
    13681 cttgtacttt tacatgttcc tcccatgtct tttcttcata atcaccatag tcgaaggtat
    13741 acaattcctt gtactcttca aataattgat cgacttcttc gtctgatacg cgatcgatta
    13801 cttgtacaag atctccgata ccaaaataat caacagtcca accaaattga atctgtgctt
    13861 ccactttgtc tccttctgtg acacccacgt ttctcatgtt gtcaccaaaa cgagccactt
    13921 ttattccaaa attatatggg attttagatt atctttttag aagttcttga atgtcggtat
    13981 agcccgtgtt tccgggcttt tccggcattt ttgatattgt tagatactta caaatgttct
    14041 tattacctct caccatttcc ccctcaaaag tagtaaatgg agtagtaaaa ccggccttgt
    14101 gtcaggctgc cagccgttcc atttctgccc ttgcggaatc gaatgtggcg tgtgcataat
    14161 agttcagcgt catggtgata ttggaatgtc ccataatgta ctgcaaggct ttggggttca
    14221 ttcccgcatt ggctaaccgg gtgcagaatg tatgacgcat agcatggggc gtcgtcgttt
    14281 tcggcaacgc ttcttcatgg ctcttgttgt acttcttcac aagcctgcca aacatcccgc
    14341 cataatctac cgccgtcatg ggatagccgt tctgtttgag aaacaggaaa ttggcatacc
    14401 cgtcaataat gaacggcttt gcacctttgc ggttttttat cactcgctgg aacgcctgat
    14461 acacttcctc attcatgggg atttttctga cgccgctttg ggtcttgggt tcgtcaatat
    14521 agtaaccgac gccggtattt ctcaaaagct ggtggctcac gatgattacc cggttttcaa
    14581 aatccaaatc tttgtccgtc agtccgcaca gttccgaaat gcgaagccct gtccccagca
    14641 gaataacgat tgcgtcataa tgcttttggt aaaccttatc accttgaata aaggacagaa
    14701 aactttcttc ctgtgctggt gtaagaggca cctttggttc cgtatcgtcg tccagaacgt
    14761 cactaagctg gaagtcaaac gggttttttc ggatgcaatc gtcctgtatg gcggtgtaaa
    14821 aagccgcttt cagggaacgc ttgtcgttat tgatggtctt ataagaaagg cccttttctt
    14881 tcatccgaag cgcccattcc tttgcgtcgg acagcttcac actgtcaatc gggcagctcc
    14941 ccagccgatc ttgttccaga atacgcatca gccgttcccg gcccagtttg gtgttgtgct
    15001 tcacattgcc ccggtgcctg atctgcttgg cgtagagctg gcagacggtc attttcttgc
    15061 cgatggtgtc tatcccgtcg tcaaggtctt tctggatttc tttctccttt tcccggagtg
    15121 aaatatcctc ccgtttacct gccggggtct tatccgtagg cactaacttc catgagtaaa
    15181 caaactgcgg ttttccaaag gtatcaacat atttgtaagc atatcgtccg tcttttctct
    15241 ggctctctcc agaccgcaaa acgcgatttt tgctgtctcg tcttttttct gacatctcgt
    15301 catgctcctt tccatgacgg aaagagccgc atatatgctt ataaattatt ataacatatc
    15361 tgcggccctt tttcactatt agattgtgtc caaagtgtca attattttct caaactgctt
    15421 gcgtttgatc tggatgcggt tgccattcat aatgacccag ccagaggccg gattttcctc
    15481 ggccagctta cgcaatttgt tttctccgat acggaaatat ttagacgctt cctcaatcgt
    15541 cagcgtgtat ttttcccaaa taggcacatc atggttcata atgcagcccc ctttcacaaa
    15601 ttcaaaggtt tgtgtgattt aggggcatag acggacggct gctggcacag ctccacggga
    15661 ctttcacccc cgcgtggttc tcacgcggcc ctacccattg cctgcgacgc ttttaacgct
    15721 cggactgtgg ctataaggga gtatcatagt cctgcctgta cgtcgtcgcc cgcaagccgc
    15781 cacgctcaca ttgcggcgtg gtgttcctcg ctccgctttt cccgtaggga aaagtatcat
    15841 ggcgcaccag ccgtccggct cggcacagac agaatgtgtc cgtatgccct atgatgcgcc
    15901 gccgttatct tgcgggcata tttatcaagg tgcgatcagg ccaccgggaa aacaccgaaa
    15961 cggggaaagg gtaagccgtt tcatgctgcc ggggccggtt cgtcagttcg tgacgatagc
    16021 gtggatgagc ttgatttcca gacggcgctt catggcctcg tccagacaca catgcggata
    16081 gccgttttcg tcatagagcg tccgggtaca cagcttgttc atgtaaccgc tgtaatactg
    16141 caaaacgcgc tctacggctc cggcatcccc agcgcgggcg gcctcgatca ccgaaagggg
    16201 caaaagctca atgcccttgt agttcgggtt cttcatccgc gtctaacctc ccttcggcat
    16261 caacgccttt agctgtttcc gcagctccga taaggtattt gtcctgtgcc gctgaacggc
    16321 actccgggac attcccacaa ggccgccgat ctcaccatct gccatatcca gaacacagtg
    16381 caggattaaa atactctgct ccatgctggg cagcgcggca aaggcttcgg caacaagctc
    16441 attgttgata tgtaggtcat agccatgcga cgaaaacgta aagctgtcgc tggggtagtg
    16501 atctactgta cagagcttgt ccaaatctgc ctgtgacaaa gagcttagtg acacttcacg
    16561 gtcacggcgg cgcttcattt cagccaagta gcttttggcc tcgttacgca gtaccgtctt
    16621 gcaaaaagca tcgaacatgc accgcgcttc atagtcgcgg gggatagcat ccatcttctc
    16681 accccctttc tgtgggggac ttaggtggtt ctctcccttt ccgctaacaa gactttgaca
    16741 aggccgccag ctacccgcta aatacctcct ttttgaaaat ttctcaaaaa atttttttgg
    16801 ggacagccgg gccgcaaaag acgacaaaaa tcgcccggca ggtcgcaaac ctaccgggcg
    16861 agaaaatgct ttgctatgct gctgatttac atggtatagt acatactcat aaccggaata
    16921 gccctgtg
//
LOCUS       DAZUJR010000063        16566 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.063, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000063 DAZUJR010000000
VERSION     DAZUJR010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16566
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.063"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(123..1433)
                     /locus_tag="ACG804_002019"
     CDS             complement(123..1433)
                     /locus_tag="ACG804_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004650 - polygalacturonase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 28 protein"
                     /protein_id="HFS4832942.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1445..2863)
                     /locus_tag="ACG804_002020"
     CDS             complement(1445..2863)
                     /locus_tag="ACG804_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4832943.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3103..4671)
                     /locus_tag="ACG804_002021"
     CDS             complement(3103..4671)
                     /locus_tag="ACG804_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HFS4832944.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(4675..5085)
                     /locus_tag="ACG804_002022"
     CDS             complement(4675..5085)
                     /locus_tag="ACG804_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HFS4832945.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5082..6005)
                     /locus_tag="ACG804_002023"
     CDS             complement(5082..6005)
                     /locus_tag="ACG804_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030599 - pectinesterase activity
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pectinesterase family protein"
                     /protein_id="HFS4832946.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6002..6880)
                     /locus_tag="ACG804_002024"
     CDS             complement(6002..6880)
                     /locus_tag="ACG804_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HFS4832947.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(6867..8204)
                     /locus_tag="ACG804_002025"
     CDS             complement(6867..8204)
                     /locus_tag="ACG804_002025"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HFS4832948.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8207..9310)
                     /locus_tag="ACG804_002026"
     CDS             complement(8207..9310)
                     /locus_tag="ACG804_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFS4832949.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9384..10892)
                     /locus_tag="ACG804_002027"
     CDS             complement(9384..10892)
                     /locus_tag="ACG804_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFS4832950.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(10858..11550)
                     /locus_tag="ACG804_002028"
     CDS             complement(10858..11550)
                     /locus_tag="ACG804_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HFS4832951.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11572..12546)
                     /locus_tag="ACG804_002029"
     CDS             complement(11572..12546)
                     /locus_tag="ACG804_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4832952.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            12846..13718
                     /locus_tag="ACG804_002030"
     CDS             12846..13718
                     /locus_tag="ACG804_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4832953.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14300..16498)
                     /locus_tag="ACG804_002031"
     CDS             complement(14300..16498)
                     /locus_tag="ACG804_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4832954.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLFSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
BASE COUNT         4890 a         3477 c         2690 g         5509 t
ORIGIN      
        1 tcaactcttt tttggaattt tcataaaatg tttcaatgaa gcgcgacaac gttgtttaat
       61 atatcattaa aaaaaataaa ggtcaagcta aaatattatt taagcttgac cttattataa
      121 tttcaacgat tgtcaaaagt attgtttgca gctgtgttgc cagtttctat agataaatca
      181 cagcttttga aacataagtt ttgtactgct tcgattcgcc cgaattcttt tgcagttatt
      241 tggcaatgag aaaagcagac atcttctata ggcttttcag gaaatgctac taaatcaaaa
      301 gctcgggaag gaagtgagta acctggagaa aggcatgcct gtacgttttt gatgtgtatg
      361 tctttgactt tcgtcatttg ctttgattca ggtatttctt cagccactgc ttgccaactt
      421 tctggcattt gagcaaggtc attgctattt tttctattgt attcattatg ccagtccatt
      481 atccaagaaa aaggaaattg tacatcaatc atattcagat tttctaccct gatattttcg
      541 atcactcccc ctctttcttt tgaagatttc attcgaatac cacagtctga ctgaaaaaaa
      601 tcgatatcgt gaatatatac gtcactaact ccagcactaa cttcgctacc aatagttaca
      661 ccgtatcctg aacggatttt acatctagca acctcgattc ttgatgattt tcgattgact
      721 cttgcaccat tgccatctct gccagactta atagcaatac aatcatcacc acaggccaaa
      781 tcacattcat agacacgcac atttgttgaa gaatcaatat caatcccatc tgtacttggt
      841 ccatcattgt tgcggatgat tactttttct actaatacat cgttagaata agtgatttgc
      901 aagttccaaa aacctgattt ctgaaaaatc aaatcacgaa caacaacatg ttctgcatga
      961 tacagtaaac aagcgcgtgg acgtttaata gcataatccg caatccaacg aagtcccttt
     1021 tgatcgtatt cagctcttgt cccgcttttt tgatcttttc cccaatacag ctcccaccaa
     1081 tggtctcctt gaccgtcgat tattcctttt ccttctataa gaatatcttt cgccgagaga
     1141 acattcaaaa tcgctgctgg ccatttcatt tctacgccgg ctactcgtgt atcgatttct
     1201 ggaaatgctt cgatatctgt tctccccttg aggactgcac cttcttcaaa gataagatga
     1261 ctcttatctt ttaaaaaaag ggctccgact aaataaatgc cttttggaat aaatacaggt
     1321 aagtgttctt tcgcaccttg atcgattgct ttttgcagta ttattgtatc atcttgttga
     1381 gtgtcgtttg ttttaaagtt caaagcattg ataatccctt tttttgtccg caatacgttt
     1441 ctccctatct ttcattgatt tttttcaatt cttcaccaat aaatacagtt tttgaacgat
     1501 tcagtgggta acctactagc aaaatgattg cggatacaaa taagcagaat gctggtaaca
     1561 agtttgccat cgtataaatc ctttcttgta ctaaaactga ttggatggct ccacctgttg
     1621 tagacgattg gtaaccaatg agtgccagca taaatccgcc taccgctcct gcacatgctt
     1681 gtcctacttt tctcgcaaaa gaatttactc catatactgt tccatcttct cttaagcctg
     1741 tcttatattg atgataatca atcacgtcag taatgaatgc ccagaccatc aaattgaata
     1801 aaccagatcc taaagtagcg ataaataaaa gaatcagata tacccatgca tttgttatat
     1861 gaaggaaata catcagcaag tacatacatg aagaagcaag taacgcaaat acgcttgctt
     1921 cctttttacc aaataatttt gtcagctttg tagcaaatgg tgctaaaact actactgttc
     1981 cgtaagtaaa taaaagagca acagacattg cttgtttatt atggaagtaa tcattgaata
     2041 aataagtcat attcgtccca gctaaaatct gattgatcac aatgaaaatg tcaacaatga
     2101 ctaaaataat cagtgctcga ttagctaaca aaccttttac caactgagaa gcagatactt
     2161 tttcgttttt gacaactctt actctttcag tagtcaattt acaagttaac atatatgcga
     2221 caaatgctat tgcagcacat ccgattgaaa tccaaaagaa atgattccct gaaacgactt
     2281 gttgtccact cttgttatgg gtatacatta aaatcggaat gaagaatcct gtagttgatc
     2341 cgccaatcgc agaaccaatg cttcggaacg tggacaacga ggtgcggtca ttaggatttg
     2401 agctaattgc tgctgccatt gctccatacg ggatattgat tgttgagaga aaaatcccat
     2461 aaacaatgta tgaaacaaaa atataagcaa tcttcaccgt cattggaaga tgttggacga
     2521 atggcaaaaa caaaatgaca gtcactaagc aaaatggata cttcattttt ctgatccaag
     2581 gaataaatcg gccagtttct gttaactctg agacatcaca taatcttcca accatcacat
     2641 cagcaaacgc atccaaaatt ctcgaaatca agaataacgt acctacgatt gcccctgaaa
     2701 cgccaagaac attcgtataa taaatcatca agaaactatt gactaaacct aaaataaaac
     2761 agttacctag atcaccgaac atgtagccta tcttatcgga aatcccaaat tccttttttt
     2821 ctttttttat tgtatttgct gtaacagcat tttgtgaaag catttgaatt cctcctacct
     2881 cttctagtaa acgttttcaa aattataact ctttttttct tgtttttata ttcacaatgt
     2941 tggcttttta ttgcattatc ttgacagata aaaaacaaaa aataatctaa aaacattgat
     3001 gcataagatt gataactttt tttacataac aatatataca aacaaaaaaa ttcactaact
     3061 agtgaaaata agttagtgaa cctcatttat taaagaatta aattacagat gatcttttcc
     3121 atcatacttg aaaaactcaa aatcagcata acttcctctt tttttattta gatcatgcac
     3181 tgctatcccg ataaaatttc cagtaaaccc tcctgagagt atacacatgt ttttttgcgg
     3241 acctactttc ttccattctt cagttgatac gtctttcaaa tgaaactgtg ctgtctcttt
     3301 ctttacagtg actttcaaaa aagtcttctt ttctgtgagt ggaatcgtcc aatcttctat
     3361 ttgtgctact ccgttttctg attctatcat acgtaggcat tttcccttgt cctcattcca
     3421 agtaacataa caataaatat aattggattc atttaagtac agtaccagtc cagccatctg
     3481 attaaaatta ttaggcatgt attcaaatgc tgtctccgca tcaaaagtaa aatccgtttg
     3541 ccgaatagct aacaaatgat gttcgaaggt agattgaaga gattcaccgg aaatcagacg
     3601 taaaaaacct ggtctacatt ttgtatcaca ccaatcagca tttggcaaaa tgcgtctggc
     3661 attccagttc ttctttagct ctccttcaaa tgtatccata aactgatgat ctttttcttg
     3721 ttgtacctct tcatttgtct caatcattat ttcttccatc ggagttgtct ggctatcttt
     3781 aagtcttaac caatcgtcgg acgtccaata cacttcttga atagcggttt ctcttcccaa
     3841 aatagccgca ccgtttaatg gtctggtaca aagatatgtc atgtaccatc ttcctgacgg
     3901 ggtttgtact aagctcccat gtcctgtaca ttgcaatgta gaagcaggtt tgtcactagc
     3961 tgtcagcata ggaaaaccag gatcaagctc gtaaggacca gtaatattct ttgctcggca
     4021 aactgtaact gaatgtcctc ttcctgtacc gccttctgcc gtcatcaaat aataataccc
     4081 gttacgaaaa tacaaatgtg gtgcctccgt tttcgctaat tctgtacctg caaatatttt
     4141 atagatggga ccatcaagct tcttcttctc tgcatcatat tcttgtaata cgataccgct
     4201 ggatttattc ggtgtgtcca gacgataatc ccatagttca ttgacaagcc atttttttcc
     4261 cgtttcaaga tcatggaaca aagaaggatc aaagccgtta ctatttaaat aaattggttc
     4321 ggaccaagga cctgtgatct cagatgcagt gatcaaataa ttgtggacat ctttaaacgg
     4381 acggcctgca cttttgacat ctgtgtaaac aagataaaac aatccatcag cataactgat
     4441 ttgtggcgcc catatacttc catttgtagg atttccttgc aaagatactt gagtggtcaa
     4501 aatatccgtt gtatgtgacc agttgactaa atttttcgac tcatatactc ggattcctgg
     4561 aagccattca aaagaggaga caataatgta ataccgctct ttcactctta atatattagg
     4621 atctggattg aatcctctta aaataggatt tttcactttg atagtctgca tgattcaggc
     4681 tccttttctc attcttactc gatataaact gaatgcccca gctgcgaaat aaaaaaatgc
     4741 aaaaggaaac gcaataaact gagtgccaat caacaatatg aatcctgtta taaaatacaa
     4801 accagtggca gttgttaagt attttccttt agcagtcaaa aacaatgcta ctgctaaaaa
     4861 agcaagtgaa ataaacaaca caacggcaaa cagaccagtc atgtcctgta ataatccaaa
     4921 tgtattttct aaagacaaag ttgaatgatc tacagcaagc gactgataac tttttttaaa
     4981 ctctgacgca gacatattac ttaaagtaac tgctaacccg ccaaagaaaa tcaaagatag
     5041 actgccaccg accattccta gcaatagttc ccattttctt ttcatttctg aaccccctgc
     5101 ttttctaaat gtatccattc aggtcttttg atcgatgttt cataattgtt attacgttca
     5161 gagaatttga cagtctgttc atttttcttg tcatcccaat tatcccaacc agttgggtga
     5221 acatgcccac ctatcttaca cgcttcaaat aagacatttg catacggacg ccacggtctt
     5281 cctaaataga cgtttctagt atcaggttct gcagtcaagg tacagctttc aaaacgatac
     5341 cctgtttttt gatttttcgg cgtagatgct gctgtgatgt atccaggatt tttactggct
     5401 aagctatgga tatgacactg atgaaaaacg gcatctgccc caccaaatat gaaatccacc
     5461 gttccttcaa tccagcaata ttcataggtc tgacgacaat actcaggatt ggcagaagcc
     5521 ggtgtacaaa aaggagtacc atctttttgc aaatcaggca acggacccgt gcataaggta
     5581 tcctgataac cagatagtcg acagtttttt aaagatacgc gatctcctga attgaataaa
     5641 gcaacagcct gtcctacctt ttctcctgga cctgctgtat tttcgatgtg aagattttct
     5701 aatacgacat tcgatccttc taagaaaaaa gtagcacttc ggaaagtccc taactggcta
     5761 ccgtcaagat actcctgttt tgcaaaacga ttaccggaga taactactgt tcctgctccc
     5821 acaagtttaa aattggataa tctgctttct atatattcat catatcttcc ttcttttact
     5881 atcaagacct ttggatggct atccggcagg cctgccaaat aatcgattcc ttcttggata
     5941 gtttcaaaat ccgtcggggt atctatagca ttctttccaa ttatcagttt gtctttcatc
     6001 ctcataaatg ctcccttatg aattgtttcc aaatatttct catttcttgt gtttccatat
     6061 gaccgcctgt taaagaaaaa gaagaaaagt tttctggact acccattgat tgatactttt
     6121 tgtccagccc ttttctcagc ttcagtacgc cttcgtccaa gcacatcgta tcgttttttc
     6181 caactaagct aagacgaggg cgcggagcga ttttttcttg gattgctaac gttgtataag
     6241 ctgtcaatag atttggcaca tagtaataaa acccatgatg atctaggcgg cgatgtagca
     6301 aaagtatttc gatgtccacc tgtgccgcta gatcaataca aactttgaca cgagaatcca
     6361 atgctgtcac ccaccagctt aataagcctc ccatagaaag accaatcgtt gcgagccgtt
     6421 gagtatctgt gtcttccctt gtctccaaat aatcgatcaa gctgatcaca tcataaatac
     6481 gcattcccca taacgttttt cctgttaata aaaattgttt gaacaactcg ctttcagaaa
     6541 tacctccgcg ttcttcaaat ccccaagcat caatcgacca aacagcatat cccattcctg
     6601 tcagtacttc tgcaaaagat ggagaagcta agtaaggagc accatggatc aattcacttt
     6661 tcccgactga aaaatctccg ccgtgagaat gcaggtaaag gaccggcgga aacggtcctt
     6721 ctttttctgg ataagcatag agggctggta ctgtttccaa ttcatttaag tacaattgat
     6781 agtattcaag cataaaaccg ttttgttttt ctcggtataa tcgttttcca ctaggggtat
     6841 gtctgctaga tggagcacct aaaaaatcat tcaactgcat aagcaaagtt tttacgaaca
     6901 accagttcat ccatattttc tgattgattt gattggaatt tctcaatact gatttcttta
     6961 gtattttcta atagaaatgc tggtccctcg tgattttcaa tcgacatctg gttaaaggaa
     7021 accttacccg caaagccaat ataaaatcct tgtctgctca tttcctctat tcctgtcatc
     7081 atagcaggaa caccgggaac tgcatcttgg gccatcgaga catcgatatt gtcaaatgtg
     7141 atttcttgta tgaattgttc cgctaatcca taaataaaac ctgcagaagc atggacattc
     7201 cttgccgtga tattcgaaaa atggatcctt ctgaatgctg gtgtccgttc atctatcgga
     7261 taagcctttt tttcccatac atacggttct ttccctcgcg gaccacagaa ataataaaga
     7321 ttcagtataa atggacacat cacattatcc atgactatat tggatactcg aatatcttca
     7381 acgatcccgc ctcgacctcg tctagatttc aatcgtattc ctcgatcagt ttcttggaag
     7441 atacaatttg aaatggtaat attacgaata ctaccactca tttcacttcc taatacgaca
     7501 ccgccatgtc catggaccat cgtgcaattt gtgatcgtga tattttcgca agcgatcctt
     7561 tcgtacgtat cttcagtccc tgccttgatt gcaatacagt catctcccac gtcaatatgg
     7621 caattactaa tacgcacatt tttgcatgat tctggatcaa ttccgtctgt atttggtgaa
     7681 tccgctgggt tcaagatcgt caagttatca aacgttgcat tactgcaaag aatcgggttg
     7741 atcgtccaac ttggtgactg gatcaattta atatctttca cagtaattcg atgacagtta
     7801 tggaaactca tcaatttagg acgaggataa gcgagattat ctggttcatt tctaaaagta
     7861 tgccaccatt tttttccatt tccatctaat gtaccgaaac cagtgacaga gatgttctct
     7921 acattttgag catagataca ggaagcataa acttttcgat ggactccttc ccaacgtgaa
     7981 tgaacaacag gataatcttt tggatcgtca gagaatttca gaaccgctcc tgcgcttaaa
     8041 tgaagttcga cattgctttt taaaaataaa gctcctgtta gaaattcacc tgctggaaca
     8101 actacggtcc cgcctccgtc acttgctgca gcatcaatgg cttgttgtat tgcttcagta
     8161 ttcaattcat caattgatgc gccaaatgtc aaaatatcat acatatttat aatgcctcca
     8221 cttcaatcaa tgcttgcaag aatgcaccaa cgcctttttg atcattacaa ataattggtt
     8281 cactgatgta gtaagcatat gaaccatctc gctgatctgc tccgcctaac cctgctactt
     8341 gacagttttt attcaagttc agccagcctt cttttgtttc cagaacaaat tcatcaagta
     8401 atccttgatg tgatttcttc acttgtggaa gccattcttc tttgttcagc agtcccaaac
     8461 gtattccttt agccattgcg taaacaaaca tactactgcc ggaagcttcc agataatttc
     8521 ctttccgttt tgtttctgtt gttacttgat accatgtccc gctgttttct tcttgatatg
     8581 gaagtaatgc agccagtgtc ttttctagaa tttctttcag caaagaacaa tctgtttctt
     8641 catgaagtaa ttcataggta tctgctgcag ccatcaaata ccagccaatc gatcggctcc
     8701 aaaaatgatg ggatagacct gtttttggat cagcccatgg ttggaccttc ttttcatccc
     8761 atgcatgaat cagcaaattt gtttttggat cgaatagatg tttataactg atttcaaact
     8821 gtctcaaaac atcttggtaa tctttttctt cactaaaatt ctggataaat tcagcataaa
     8881 aaggagaacc catatataag ccatccaacc aaatttgata aggataaatt tctttatgcc
     8941 aaaaagctcc ttcggatgtg cgtggatggt ttgccaactg ctgggaaagg agttctgctg
     9001 cttttttata tttttcttcg cctgtttctt tgtacaataa aaagaaaagc tttcctgtat
     9061 ttacatggtc gatattgtat tcttcaacgc tgtagccacg gatcgttcca tcttcttgca
     9121 cgaaatagtc gatattgtct tttatgaaat caaaataaat tttttcttgg gttcgttccc
     9181 aaagtaattg gaacccttta agtacgacgc catagtcata agaccatttt cctttatacc
     9241 acttttcttc atataagcga ggtgttcttt ccatgatact ttttgctaat ttctttgacc
     9301 agttttccat tatttgctct cctttaaaaa ttaaaatagg atttgggaca aataccaaga
     9361 agtatttgtc ccaatcgtct atattactgt gccgctgctt tgtatgcttc ctcgtactct
     9421 tgtgtgattc gatcgcctcc ttgtgctttc cagtcttcta cagctttttt gaatccatct
     9481 tcgtcaagct gtcccatgat gtattgcacc gtagcatcaa tgacgatttt ttcaatttct
     9541 gatcctactt cattgttcgt cggtgaatcc aatggcacag aaggatccat tacagcaaat
     9601 tcttcatttt ctttgatcaa ttgattagag aattcttttt cagggtctgt atctttgaaa
     9661 gagaacgtca cttcactagg acgagagctt gataacggtt gcacctcttg ttgccaaaga
     9721 tccatatcga taaattcgat agaaccatca tcattcaatt cataatgcgt tccttcgata
     9781 ccgccagtca tcaatttata cacatcttct tctaaaagat catcaacaaa ttgaagtaat
     9841 ttcttcaatt gtgcttcgtc ttttacttga gatttgggaa atgctagcaa gccgccaata
     9901 ccatttcctt ctgaccaaac atgataaccg ccgccttcac catctgagat cttgtttaca
     9961 ggcactaatt ccatatcatc ttgaatacct tgacccatcg tcttcagatt cttgatatcc
    10021 accattccag tgtagattcc agttcttcct tgtgcaaatt gttcttgctg atcagtcttt
    10081 tgggtaactg caaagtcttg tgccaaatag ccattctcaa atagatctct tgaaaaattc
    10141 aaagctttca tatactcttc tgtatcaaat tctggagtga atttgccatt atcgtctaca
    10201 gcccagccat ttggtgctcc aaaataagaa gtgaaaagtt taaagctggt ataacgaata
    10261 tcactaggcg cacgatcgcc aaaaccaact gtgtcgtcca caccatttcc atcaggatcg
    10321 ttttctgtaa attgtttagc tacttcataa agctcatcca tggtagttgg aacatctagt
    10381 cctagattat ccaaccagtc ttttcgaatg actaagccag cacgagcgta gtctttttgt
    10441 atcggtacgc cgtacaaggc accgtcgata ctcgcagctt cgattctatc ttcagaaatt
    10501 tgacttaaat ttttatagtc ttttaaatat tctgatacat cccagaatac gcctgatttt
    10561 aacgcattgc ggacagaaga gtttttcaac atcgcaattt gaagtgtaac gatatctcct
    10621 agttcatcag aagccaatgc agttgttaat ctttcttctt ttgaagcatc aggaatccag
    10681 ttgaatgtca gttccgtatc ggttttttct tcgatcaagt tcacaatcgt gtctgtaggc
    10741 ggtgaagcat gatgcaaaat atttaaccaa gtgattttag cttttccatc ttctgtctct
    10801 gaagaactgt tacttgaact gctgccgcat gcggcaagtg ctagaattcc tgcaaaacta
    10861 agacctaatt ttacgagcgt tgcttttttc ataaattttc tccttcactg ttttaataat
    10921 atttttgttt tcttctgttt tttctgtata tgagttcttc cattccaaat ggcaaaatat
    10981 agaatttgct gtccacgtga ctgcggaaaa gaagagactg ccaccgataa aggttaaaac
    11041 acctggcatt gtttggatga tcatcagata aatccctacc atacttaata tcaacactaa
    11101 tgagtaatga agatgtgaga atccgaataa aaatgccatt ttcattttga aaaaatatcc
    11161 tttccaatca taatgagcca tgattgggaa aatatagagt gctgagagca catatatgaa
    11221 cgcagcaata tacaaagcga tcctaagata ccaattgtgt atgaaagaaa gatccacaag
    11281 taaaacaatc ccgatggcgc catatatcca gctcatcagc aaggtttcac gatagttttc
    11341 tttaaaatat gtgaagtacg ttttcgtcaa aggaaacgtt tcttttgagc gcagccattt
    11401 tctaatcact gcaaccatcg catacgatgc aggaccgaaa gtaaaaactc ccaaacctgc
    11461 gatgactaaa ccgccccaca gaaaattcaa ataaaccaac tgtaaaatac gatttagcct
    11521 tccgtttatt ttatctaatg actgcagcat atctttccct ctctttctat cttagtaaac
    11581 gccgtcttct cctagctttt tggcaatctt attagctaaa attaccataa acaatcctac
    11641 gaccccttta aacaatccca ttgctgtact gaaacttaac tgtccattct tcaatccagc
    11701 tgtataaata taggtgtcga aaatttctgc aacgcttcga ttcaatgaat tcaataacaa
    11761 gtacatatgc tcgaacccta agtctaatgt ctgaccgatt tttagaatca gcaaggtaat
    11821 gattactgga cgaattgccg gcaatgtaac atgccatgtt ttgcgtaagc gtcctgctcc
    11881 atccatttct gcagcttcat acaactgtgt atcgactgca gttatcgctg aaaggtagat
    11941 gatcgtagac cagcccaact ctttccagat cacttgtccg atatatactg tgcgtgtcca
    12001 ttcaggggat gttagaaaac tgattttttc aaatcccatt gttgcaagga attcattcaa
    12061 tacccctccg tcaacattca aaaatacata agtaatcgaa acaatgatta cccaagacat
    12121 gaagtgaggg atgtaaatga tcgtttgaat cccgtttttc aatcgtttgt tcgttacttc
    12181 atttaatagt aaagacaaaa tgattggcat cggaaaaaac acgaagatat ttaatccgaa
    12241 caagatcaac gtatttctta ataatgtaaa gaatgtcggt tctgtaaaca aacgaatgaa
    12301 atgtttgaaa ccgacccaag gacttcccat tattcctaaa aatggttgat aatcttgaaa
    12361 agcaataacg agtcccccca taggaagata cctaaaaatc aagaaataaa ggactcccgg
    12421 cagaatcatc acatataaaa atttattcgt tttgattcct gcaattattt tttttcgtct
    12481 tctgagcttt tcttcttttt tcgatagcgt cagttgaaat ggttcttgtt tctttacact
    12541 ttccataagc ccctccttag ttttgtgaat gtttgctgct tatgacttca tgatagataa
    12601 ctatctgaat tacgtatata atcattttta ccgtaagtaa aaacgcttac atagcaatga
    12661 tttttgtgct atacaaaacg ataaagtgta ttttttcaca aataaactac gcatagcaaa
    12721 ccttctattt ttttctatct gacacttagc ataggaaatg attatatacg taatctttca
    12781 ccgatgataa attgaacata tagaaacaga aacatttaat ttattttgag gaggagccta
    12841 tctatatgaa aaagaaagtc tctataggag aaagaagttt tacacttttc aacaatacgt
    12901 ttctaatttt gctagctttg atctgtatcg ttcctttttt aaatatcatc gctacatctt
    12961 ttgcttctac acaagaagtc gtcgcgaaaa agtttatcct ttttcctact accttttctt
    13021 tagacgcgta tcgctacatt ctttctacgc cgaccatttt tagagcactt gctgtttcga
    13081 ttggtgttac aggtgtcgga acgatcgtca gtatgtgtgc aacttcactg atggcctacg
    13141 gtctttccag aaagtatttg tttggtcgag gtttcgtcaa ctttcttgtt gtattttcta
    13201 tgttgttcag cggggggatg attccaacgt tcttagttgt tcgttctcta gggctggtca
    13261 attcttactg ggccatgatc ctgcctgtgg ctgttaatgc aatgaatatg atcattatga
    13321 gaaacttttt ccaagccttg ccggatagtt tggaagaatc agcaaaaatg gatggttgca
    13381 cagattttgg tgtatttttc aaaattatgc tgccattagc tttaccgtct attgctacta
    13441 tctcgctttt ttatgctgtt acttactgga acacttatat gactgctatt ttgtatatca
    13501 acgattcatc taaatggccg atacagattc ttttacgcca aatcgtcatt gtatcaagtg
    13561 ggatgcaagc agaaagtagt gccgttgatg tgattccacc agcacaaaca gttaaaatgg
    13621 ctgttatcgt tattgcaaca gtgcctatgc tgattgttta tccttttgtt cagaaatatt
    13681 ttgtcaaagg agcactcgta ggttctgtca aagggtgatt atgtactgaa cgcaaaatgg
    13741 tagttgtgtc agaagtggtc agcttcaaga aataagaagg catttacgaa aattgcttct
    13801 taaatttttg tgaaatttcg gcttattttt cgaagaatct actcctggaa caccgtgtat
    13861 cagaggttgt gaaagagacg ttcagccttg agcgatgata aaaactctca caaacattgc
    13921 gacgagtaac ccacaggagc aataagaagc gattttgaaa aatagcttcc catatttcac
    13981 aaaattatgc cttattgtcg atagcctgtc tcttgaacgc catttattcg taaaaaagaa
    14041 ctgtgacaag acttttgtca cagttctttt tgcgtgctta gccttgaaat ttaactatcc
    14101 ataaatacaa atactagggt tattctaact tcttttattg cttgaatcag tccacaagaa
    14161 aaacagcctc ttgattaaac ggcgtttatc ttgttgattc tgcggcaata aaatcagcca
    14221 gcagcaaaac atgaagtgct gttttttgct gtcctctttt attgcttgaa tcagatcaca
    14281 agaaaaacag cctcttgatt cacaaatatt tttttcgata ttctcccggc gtaatcgatt
    14341 ccttcttttt aaagaaacga ataaaatttt gcggatttcg atattgcaat ctttctgcaa
    14401 tctcttttac ggagaggtta gtctctttca accatttttt tgctacctct aaacgatgat
    14461 tttgaacaaa atcaccaaat ttttctcctg tttccttttt aaatacatta cttaaatagt
    14521 tagggttata atgcaaccta tcagcgatca catctaaaga cagatcacga tcatattctg
    14581 tgtagacgat atgcataata ttctccgaca aatttttaaa ttcatgatca gtgattgctt
    14641 gagagcattc tgtgattggc agaactaatt gttctaaaac aagtttttct agttctttgg
    14701 gatgataatt gttcagtgct tttacataaa tttgtttcat gttatcaaag ttttttgaat
    14761 ctactcccaa taactgtcct aattgaacga gttcattgat caagcggacc gaaactactt
    14821 cccgactcaa aggattttta ttttgtgcaa acaatgcatc aatcaattca tgtactaaat
    14881 tcttcacttc ctgatttcca gaacgaatgg cttcaaacaa tcgattttgt tcttctatcg
    14941 gatatctaat aagtgttttt tcatgagcag caggaacgat ttcctgataa aaaataattg
    15001 aacttggacc agtatttaca cgataataca gggcttcttt tgcccgatca accgattgct
    15061 tgctttcatt cagcgtttcg aaccggttac tgatgcctat actgatagtt aaattcaagt
    15121 attcttttac acgtttttga atgagtcggc aatactccat gacttttttg cttgcttctg
    15181 catcatcttt atccattcga taaatagtgg cttgcatttc ttcattcaaa acgatcggca
    15241 gcattcgatt ttcctttggc acaatttccg tgatcatgtt gttgatcgct aaaagtagca
    15301 aatcacgctc cccaccgtga ctatcttcta acagatcgat ttgaaccaaa gctgtataat
    15361 agcagtcatt ttgagaacta taaccaaatt gctgcaaccg ctgatctagt tctcgccttt
    15421 ctactcgatt tctaaataaa ctaagtacaa atagcgtttc cagctgtggc ttttgggtaa
    15481 ctaagtgtgc acttaacgct tctttttctc ctatgatccg actgactgat tgagcgacca
    15541 aatctagttc tttcccactg aatccttttg atttaagatt cagacgttcc tgtatttgag
    15601 aaatcggacg ggcaaatctg tccgaaaata agtaggaaaa aagaccaatg agtcctacca
    15661 gtgttaaaga cactgcaact agcccgattc tcagattgcg gatcattgcg ccaattgcac
    15721 tagagtcaac ttctaatctg taaatccaat tattataatc tgatttcagt actatatacg
    15781 ttttatcttt ttctcttatc actttcagct gattgtaatc tagatccacg tccgttaata
    15841 cagttggttg ctctttattt tttactgtct gagtagtaaa aaggttgcca acttcgtttt
    15901 caatagaaag tatgtcttct ccactttcac caacaacttg ttctattgta tgtttctcta
    15961 tcgtagcaat tcccaatgca tatttttctt tttcaaacat tggcaaagaa atcaccattt
    16021 cgattccttt gtttttcttt tgccaaaata aattattttt gttatttatg tacttctgtt
    16081 gatacttttc aacttcctct tcggtcagtt gactcaacga tccattgatt actccccatt
    16141 taccagccaa actgactaaa tcataattat tatcatccat aacaatcgtt tctataaaat
    16201 ttagttcttt cctgatttca gaataagtgg agtaatctgt atatgtcagc ggatgcttga
    16261 atatgtccga gaaatttttg gtcgaaccat acgtagaaaa cgaatattca atcgttctaa
    16321 ttttccattc aacgttagtt ttaacttgcc tgagcaaatt ctttttgtct gttaaataac
    16381 tcgattcgat cgattcatag gtattctggt aaatgaataa actaaatcct atgacaagta
    16441 cggctcctaa taaaaacatc ggtaaaaata ttttataaaa tactgtactt ttcttcattt
    16501 tcttcctctc ctccttttaa aataaaaggc tttcattttt ctgtaaaatt gatactcatc
    16561 taatta
//
LOCUS       DAZUJR010000064        16507 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.064, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000064 DAZUJR010000000
VERSION     DAZUJR010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16507
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.064"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(27..725)
                     /locus_tag="ACG804_002032"
     CDS             complement(27..725)
                     /locus_tag="ACG804_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HFS4832955.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(718..2070)
                     /locus_tag="ACG804_002033"
     CDS             complement(718..2070)
                     /locus_tag="ACG804_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurT ligase domain-containing protein"
                     /protein_id="HFS4832956.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(2293..3693)
                     /locus_tag="ACG804_002034"
     CDS             complement(2293..3693)
                     /locus_tag="ACG804_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HFS4832957.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            3854..4591
                     /locus_tag="ACG804_002035"
     CDS             3854..4591
                     /locus_tag="ACG804_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HFS4832958.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            4716..5195
                     /locus_tag="ACG804_002036"
     CDS             4716..5195
                     /locus_tag="ACG804_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HFS4832959.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            5192..5959
                     /locus_tag="ACG804_002037"
     CDS             5192..5959
                     /locus_tag="ACG804_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6681 family protein"
                     /protein_id="HFS4832960.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            6189..6758
                     /gene="lepB"
                     /locus_tag="ACG804_002038"
     CDS             6189..6758
                     /gene="lepB"
                     /locus_tag="ACG804_002038"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFS4832961.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(6862..7464)
                     /locus_tag="ACG804_002039"
     CDS             complement(6862..7464)
                     /locus_tag="ACG804_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HFS4832962.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            7570..7800
                     /locus_tag="ACG804_002040"
     CDS             7570..7800
                     /locus_tag="ACG804_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832963.1"
                     /translation="MPISFVKDREEKGKCVREILLDLPEWFGLPESTEKYIEESSKLP
                     LWCEKRKEEYLGFITLSQTSEDTAEIYSIVWE"
     gene            7791..8039
                     /locus_tag="ACG804_002041"
     CDS             7791..8039
                     /locus_tag="ACG804_002041"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF025054.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4832964.1"
                     /translation="MGIKKDYHHQGLGTKLFKEAEGYAAKHYKYLQVKTVDEGHYSIY
                     DQTICFYESLGFSRLEVFPNLWDEWNPCLVLVKKLEQK"
     gene            8145..8729
                     /locus_tag="ACG804_002042"
     CDS             8145..8729
                     /locus_tag="ACG804_002042"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HFS4832965.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            8732..9805
                     /gene="prfA"
                     /locus_tag="ACG804_002043"
     CDS             8732..9805
                     /gene="prfA"
                     /locus_tag="ACG804_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HFS4832966.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            9798..10637
                     /gene="prmC"
                     /locus_tag="ACG804_002044"
     CDS             9798..10637
                     /gene="prmC"
                     /locus_tag="ACG804_002044"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HFS4832967.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            10630..10809
                     /locus_tag="ACG804_002045"
     CDS             10630..10809
                     /locus_tag="ACG804_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832968.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            10831..11856
                     /locus_tag="ACG804_002046"
     CDS             10831..11856
                     /locus_tag="ACG804_002046"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HFS4832969.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            12047..13291
                     /gene="glyA"
                     /locus_tag="ACG804_002047"
     CDS             12047..13291
                     /gene="glyA"
                     /locus_tag="ACG804_002047"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HFS4832970.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            13444..14391
                     /locus_tag="ACG804_002048"
     CDS             13444..14391
                     /locus_tag="ACG804_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase fold domain-containing
                     protein"
                     /protein_id="HFS4832971.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            14525..15154
                     /gene="upp"
                     /locus_tag="ACG804_002049"
     CDS             14525..15154
                     /gene="upp"
                     /locus_tag="ACG804_002049"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HFS4832972.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(15293..15535)
                     /locus_tag="ACG804_002050"
     CDS             complement(15293..15535)
                     /locus_tag="ACG804_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832973.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            15656..15728
                     /locus_tag="ACG804_002051"
     tRNA            15656..15728
                     /locus_tag="ACG804_002051"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:15689..15691,aa:Thr,seq:cgt)
     gene            complement(15847..16485)
                     /locus_tag="ACG804_002052"
     CDS             complement(15847..16485)
                     /locus_tag="ACG804_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HFS4832974.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
BASE COUNT         5631 a         2947 c         3319 g         4610 t
ORIGIN      
        1 ttgtcacatt cccctttttc gaataactag gctgtttgtc cttcaagata gggcagatcc
       61 aattctttac cgtaacgttg ttctaaagct aggcggatca aacgagctgc caggttctca
      121 tttcttgcaa ggataggtcc atggaaataa gaaccgaaga catttcggta aatgacacct
      181 tcagattggt cttcaccatt atttccttga ccttgtacca ctttccccaa aggtcgttca
      241 ccttcaccta agaaagtccg accattgtgg ttttcaaatc cataataagt ttcattgaat
      301 tcttcgttat ggataacgat atcaccgata aaccggttat tttcctgact taacgtgtag
      361 tgatccagtg cactgattcc ttggatcttt tctccattag ctcccatgta gtagtgacct
      421 agcaattggt agccaccaca aatggctaac atgacgccat cattttcgat atagttgatc
      481 aaagaatctt tctttttctg gatgtctttt gaaatgatta attgctcaaa gtcttgacca
      541 ccgccaaaga aaaccaagtc atatttatca gcatcaaaag gttcatgtat actaacgatc
      601 tccgtatggc aagaaacccc cattttttct gctatatatt tcaacatcaa aaggtttccg
      661 ttatcaccat atgtgttcat caaatttcca taaaggtggg cgatattgag ttcataatta
      721 gccacggttc attcctcctt tgataaatcc ttgagcagct agttctttac gaagctgcaa
      781 tacagcagtg taagtagcta aaatatagac atgctcagtt ggcaattctt tgattttttc
      841 gattacttct ggtaattctt ttgtttctgt caatttattt tctggaatcc cggcaacttt
      901 tagacgtaaa gtcatatctg tatgacggtc tcctccagaa ataacagctg ggatatccat
      961 atcggcaaag ttttcaaaat taccatccca aatccagctg acatcgattc cgtctgcgta
     1021 attggcattt aataaagcca ctaaagaaaa tggataagga gctagaccaa tcatatcgat
     1081 tacttgattg atacctacag gatttttgac aagtactaat gtacattttt tcccattgat
     1141 attgatgact tcttgtcggc cgaatacttt ctcgtcatat cctaaacctt gtttgatttt
     1201 atcaggatcg acattgaagt actctgccac tgcagtagct gctaaagcat tgtagacatt
     1261 atacataccg ccaacttcga ttccgtattc atgaccatcg atcacgaaat ctgctgacac
     1321 attgtccatc cgtaccatat cagttaatcg ataatccaat tcaggacgtt tgaagtcaca
     1381 atttggacag taatatttcc ctaagtttgc ataagtgatc attttataat gcaagatgtg
     1441 atgacaattt ggacataaga caccgtctgt attgtaatga gccatttgtt cacgatcttc
     1501 ttcatggtca aagccataat attttctagg attgactgtt tcgatagaat tgaagattgg
     1561 tgaatcaccg ttactgataa tcgttgcatt tggtgacttt gcggcaccgt ctacaatcat
     1621 tttataggtc gtatagattt ctccataccg atccatttga tcacggaaaa tatttgtaaa
     1681 taagaacagt tctggtttca tatattctgt gactttgctc aaacttgctt catctatttc
     1741 taggacagca aactttttct gtcctttttt tggttttgcc tgcaagaaag tcgatacaat
     1801 tccctgtacc atattcgcac cagtagggtt ggttagaact tcatcgaatt gctggcgcaa
     1861 aatattgact gttaaagcgg tagtcaatgt tttaccgttt gttccggtga caacgacgac
     1921 ttggtagtct tttgccaaac tatctagtat atgtggatcg actttcagcg ctagtttacc
     1981 tggtaaactt gatccgcctt taaaaaaagt ttttaatgcc cattgcgacg tttttccaac
     2041 tgcaatcgca aaatgactgc gtattcccat tatgtaacct ccaaaaacga tttgctgacg
     2101 aataaattca actaatcata ccatatgttg aaaaaaaggt taaattgctt ttcttattct
     2161 taagaaaagg ttacggctga aagtgcatga aatcggacaa aatcgcatga tttaacaaaa
     2221 aaacagcttg aaacaaaatg attgtttcaa gctgctgtga ttttattatt ccctcttacc
     2281 tatattccca ttttaaccga taataatttt ctcgcttgga tattcatagc ctagatctcg
     2341 tgtttctttt ggcacgaata acatcaatgt atatagcatt ccgatccgcc caataaacat
     2401 cagtgtagca atcgtgattt tgcccacaac agacaagtct ccggtaatcc ctaaagataa
     2461 accagttgtt ccaaacgcag aagttacttc gatgatgatc gagatcagcg tttgttcttc
     2521 tgtagcagat aaaaaaacga tacaaaagaa acacatacca agagaaagca taaagacaac
     2581 gactgatttt cgcacatcat cttgatcgat tctccgtcca aaaatattga tgttatcttc
     2641 acttttgagg aaggaatata gatacaaacc gatgattgct acagtagttg ttcgaatccc
     2701 gccgcctaca gaactaggac tgcatccgat aaacatcagt aaagaaaaaa tgatcagtgt
     2761 tgtgatttga aaatcaccca aatcgtgaat ctgcagacca gcattacgag tcgtaatcga
     2821 ataaaacatc gaattgatcc atttgacact catattggaa tcttggaata aatggtcctt
     2881 ttccaataga taaatcaaga cagttcccga aacaaacaag ataacaaaag ctaacacagc
     2941 taatttggta aacaaggaaa aacgaaacgg aagcttcgca ttggaacgtt tgtataatag
     3001 ccattcccgg cactccatca atacaggaaa accaattcct ccgacaaaaa tcaaaaacat
     3061 gatcaggatc aagaaaaaat agtcatgtgc aaagggcttg atggaatccc cagtgacgtc
     3121 aaacccagag ttcgtgacag ccgatatcgc ctgataaaaa ccgtaaaaaa cggcatcacg
     3181 ccaacgatca aaatagcctc tgtaataaaa ataaatagaa aagaatgtcc caaaaagtaa
     3241 ttgaaaccag attaaaatag caaaagtgat ccgaatcagt cggacgatac cagacaaacg
     3301 cggttgattc atatccgtca tgatcagctg tcgctgtttc agtgtgatcc gtcgtttaga
     3361 aaaaatgaca aaagcagtag aaatcatcat gatccccaaa ccaccaactt gaaataatat
     3421 ttccagcagt ataataccgt tatcattgaa cacagaattg atatcaaaag tcgatagtcc
     3481 agtcacactc actgtactga ttgccatgaa cagcatgtcc acaaaagaaa catggctatc
     3541 tggttcgcga aaaatcggca tataaaatag aacgagtgat aagaccgtca tcaatatata
     3601 ataaaaaacg atgatttgga tcgatgagaa atgattggca gcaaacttct gtcctcgccg
     3661 ctgcagcctt cgaaagaata aatcaacatg cacagtacta tcctcctgac aatagtcgtt
     3721 tctaccagta tacaagggga attaggaata ctcaaagaaa ttatcaaaca gataacaata
     3781 cagctttcga ttaaaataga aatggcttat aataaggaaa atcctagaaa aaagaaggag
     3841 gaggaataac aaattgatta atgctcaaca aatcgtagaa aaaatgaaaa atcaaaaaat
     3901 aaattatgat acagttctga aaaaaatgat catgcaatgg gagaaagaag aagtaaagcc
     3961 taagatatta atacatacat gctgtgctcc ttgcagtacg cacacattgg aattcatgtc
     4021 tcaatatgca gagatcacgt tatttttttc aaattcgaat attcatccta aaagtgagta
     4081 tttgcgaaga ttacatgaac aaaaacgatt tgtagaccaa tttaatgaga aaactgacca
     4141 tcatgttgcg ctaatcgttg atgaataccg tccaaatgaa ttcaccaaaa tggttttaac
     4201 aaaccatctt gaaaacgaaa aagaaggtgg tgctcgctgc agtgcatgct tcaatatgcg
     4261 attagatctt gttgcgcaaa aagcgcaaga actaggatac gattactttg gaagtgccct
     4321 gaccatctcg ccaaagaaaa atgcagcttt gatcaatcag atcggaatgg atatccaaaa
     4381 gatttacggg acacaatact tgccaagtga tttcaagaaa aacaaaggct atgaacgctc
     4441 tttgcaaatg tgcaaagagt atgatattta tcgccaatgt tattgtggtt gcgtgttcgc
     4501 tgccaagcag caaggatgcg atctgaaaga aatcaatcgg gaagcaaaag cttacttaaa
     4561 aacatcaacc gtagtttttg aggaaaatta aagaaatctt tcggaaaaac gtaagaaaaa
     4621 aataaagaat ttatggtaga aataaggtag actgtataat ttgtccgtag taaagtaagg
     4681 aaacaagaat aaatttcaat gaaggaagag ataagatgcg aaaagtagca cctattttga
     4741 agccaatcgc tgtattaaca atctcgacga ttgtcgcgac tactacaggt attgtgaata
     4801 gttccagcta ccgtgcacca agttcaagtt ctagtactgt agaagaaaca acaccaacta
     4861 cttcagtctc gacatctgaa ccaacaacaa cggaaagttt gaatgaaacc actacgacaa
     4921 gtacatggga cgatacaaca actagttcgt cgtatgatga gacatataca actgacagct
     4981 caagcgaaac aagtaatacg gtaccagatg gcactccatc ggattcaacc aatccaagta
     5041 caagtccgga tacaagtgct agctccgaaa cgataccaag cagtacgact gtagatgata
     5101 acacgcaaaa tgatgatgca gcacgtacag cacagcaaaa ccaagattca ggaaataccc
     5161 aaacgtataa ccagcaagca ggtgattctc aatgacattt ttactagacc ttatcaacgg
     5221 ggtgcataaa ttccttggct atttagacat cagtcctaaa tatcttaacc gtggatatac
     5281 gattttaagt gtgattccca cgctttattt attgagaatt gtttatggac tttggcaaaa
     5341 ccaaaactat cttcaatttt tcttatatgg acttgcattt ctagtgcttg tttattttac
     5401 tgttttaaat gtattttatt actttttaga taaaaacacg aaagccgatg tcactcagct
     5461 ttttgtgaag tatttacctg atgaagcgtt caacatccag acagaagaat cgatagataa
     5521 tggaaattcg atcgataaag tgaatacaca agaggtcatg gtttcttatg acgaagatta
     5581 tcaattgaaa ttagccgaga atatgcggta tttgattgga aatggtgaga tcaaaacaaa
     5641 tgaactcggt cgcatggatg gatttctggt cgatagaaat acattgtatc cttattacta
     5701 tgtcaagaaa acaggagaga aagagtatgt tctaaatatt ggacgaagct actcggacat
     5761 ggaaaaagta gggaccattc gacttgactc aacagaagac acattggaac ctgtcggatt
     5821 gttcatcgtc ggcggtgatt ttgtcaaaga cgggttacgc tatcatgagc cttatcgtct
     5881 gaaattgatt gcaaaaaagg cacagtcgca ggaagaacca gtggtttata gtcgtagcca
     5941 aagaagaaga cattcataat gtgatgaaac gccgtgtatc agtggttgcg ataaaaacgt
     6001 ttattcggaa taagggggat gtgacacgtc ttttgtcacg ttcctttttt atataacgag
     6061 aaagataaga cgaacacatc acttattctt tcctttcatt tataaacatt gtagaataaa
     6121 gaaagtacaa cgaagtattg tgaaaaaacg taataaataa cgaggaaaat acaagtagga
     6181 ggtaagctgt gaaagaattt ttgaaaaatt gggggatttt gatccttgta ttagcggcta
     6241 ttttattagc tagagtgtac gtgtttacac cagttactgt aaacgggcat tcgatggacc
     6301 ctacattaag tgatggacaa cgattgattt catctaagat ctcaaactat gaacgaatgg
     6361 atattattac tacaaaggaa ccgggggatg aagaacggat gattgttaaa cggatcatcg
     6421 gtatgcctgg agatacagtc aagatggaaa atgaccagtt gaccattaat ggcaaaaagt
     6481 atgatgaacc ttatctggat gagttcaaaa aagaattttc agaagataag ttacaaggag
     6541 aatatgctta tagctcagga ttccaagcac aagcagaaag ttcatccacc tttacgagtg
     6601 actttgaata tactgtgcca aaaggaaagt atcttgttct aggcgataac cgcttgattt
     6661 caaaagacag ccgaatgttt gggttagtcg acaaagatat gatccaagga aaagttgttt
     6721 tccgttattg gcctctttca gaaattaaaa tcatgtgatg aaaaaataaa aagaagctgt
     6781 gacatgtttt ttgtcacagc ttctttttcc gaaaattcct tcttatttct tggagttgct
     6841 cacttttttt gcaatctcat tttaagcttt ttggctgatg gataagaaaa gcgaagcgtt
     6901 tttgttcata aatagctttt ccccacgatg gaaggtatga ctagtagcag agacaaagcc
     6961 cgttttttcc aatcgattat tcaattcttc ttggctaaag ccattatgga ctttcggatg
     7021 actaatttgt tcattcttgt caaagtctac gatgatcaat tgaccgccag gagctaaaat
     7081 ttcataaagt tttgtaagaa tattctccgt atcaggaatg tgtaaaagta caagtgatag
     7141 aaggatgaga ttagcttgga cagcaggaaa ttcgacagaa gcatcagcgt ggatcgttcg
     7201 gacatttttc agatctgctg cttggatctt ttcttctgcc attttcagca tagtttctga
     7261 agcatcggca atgatcagtt ctttgaatct ttccgcaagc ggtaaactaa caagcccagt
     7321 tccgcctccg taatccagca ggactttttg gtggctgtcg cgcggtagat aagtagttag
     7381 ttcttcgcga ataatcttgg ctaatgcttg acggtcaggg gaatcataat ggttagcgat
     7441 ggaatcaaaa atattttttg tcatcaaata gctccttacg taaaactttg aaattttaac
     7501 ttattatagc acgtgaaaag aaagaaagca tgctatactc aattcaaaaa gggagaatct
     7561 agaaagaata tgccgatatc gtttgtaaaa gatagagagg aaaaaggaaa gtgtgtccga
     7621 gaaatattac tagacttgcc tgagtggttt gggcttcctg aatcaacgga aaaatatatc
     7681 gaggaatcaa gtaaactacc tttatggtgt gaaaaaagaa aagaagaata tttaggcttt
     7741 atcactcttt cacagacaag tgaagatact gccgaaatct attctattgt atgggaataa
     7801 aaaaagacta tcatcaccaa ggattaggaa caaaactttt taaagaagca gaaggttacg
     7861 cagcaaaaca ttacaaatat ttgcaagtga agactgtaga cgaggggcac tactctatat
     7921 atgatcaaac tatttgtttc tacgaatcat taggattttc aaggttggaa gtttttccaa
     7981 atttatggga tgaatggaac ccatgtttag ttcttgtcaa aaaattggaa caaaagtgag
     8041 caatagattt aatactaatc tgtgcttgat gaaaattctc actgtaaaaa atgctgaaaa
     8101 tcaagtataa taccatagga acaaactgga aggtgaaaaa gagcatggca caactatttt
     8161 ttaagtatgg cgcaatgaat agcggcaaga cgatcgagat cctaaaagtc gcacataatt
     8221 atgaagaaca aaataagcca gttgtcttaa tgacaagcgg tattgataca agagatggtt
     8281 taggcgttgt ttcaagccga atcggactga aacgtaatgc gatgccgata tttgaagaaa
     8341 cagacgtatt tgacgtaatt cagaaaatgg aaagcaaacc ctattgtgtg ctgatcgatg
     8401 aagcgcaatt cttaaaaaag aaacatgtca ttgcttttac gagaattgtg gacgaattgg
     8461 atattccggt tatggcattt ggtttgaaaa atgattttcg aaacgagtta tttgaaggat
     8521 caaaatattt attgctttat gcagacaaaa tcgaagaaat gaaaacaatc tgttggttct
     8581 gccacaaaaa agcaatcatg aatttacatt atattgatgg aaaccctgtt tatgaaggcg
     8641 atcaagtgca aattggcgga aatgaagctt attaccccgt ttgtcgaaaa cattactttc
     8701 acccatcaat gattacagaa ggagaataag catgtacgat caattacaag caattgaaga
     8761 ccgttatgaa gagcttggag aacttttaag tgacccagaa gtgatttctg atacaaagcg
     8821 ttttatgcag ctttcaaaag aagaagcaaa cacgcgcgaa acagtcgaag tttatcgtcg
     8881 ttataaagaa gtagtacaag gaatcaccga tacagaagaa ctgcttggtg aaaaactgga
     8941 tgatgaaatg gctgaactag caaaagaaga attatctgaa ttaaaaaaag aaaaagaagt
     9001 cttagaagaa aaaatcaaga tcttgctttt accaaaagat ccaaatgacg ataaaaatat
     9061 catcatggaa atccgtggag cagcaggcgg agacgaagca gcattattcg ctggcgatct
     9121 tttcaatatg taccaaaagt atgctgaagc acaaggctgg aaaacagaag tgatggaagc
     9181 taacgttacc ggaatcggtg gatataaaga agtgatcatg atgatcaccg gagacaacgt
     9241 atattcgaaa ttaaaatatg aaagtggtgc gcaccgcgtc cagcgtgttc cttcaactga
     9301 atcgcaaggg cgtatccata cttccaccgc aacagttgtc gtgatgccag aagctgaaga
     9361 agtagagatc gatattgaag acaaagatat ccgtacagat atctatcatg cttcaggtgc
     9421 tggcggacag cacgtcaata aaacagcatc tgctgtacgt ttgactcact taccaacagg
     9481 gatcgttgtt gctatgcaag atgaacgttc tcaaatcaag aaccgtgaaa aagcaatgaa
     9541 aatcttgcgt gctcgtgtgt acgataagat ccagcaagaa gcacaaagcg agtatgatgc
     9601 caatcgaaaa tcagcagtcg gaactgggga tcgttcagaa cggatccgga cgtataattt
     9661 cccgcaaaat cgtgtgactg atcatcgtat cggattaact atccaaaaat tagatcagat
     9721 tttagcaggg aaattagatg agatcgttga tgcattgatc atgtatgatc aaacatcaaa
     9781 actggaagct atgcaaaatg ggtaaaatga cctatcgaga agtcctgtca cgggcttctt
     9841 cttttttaga ggatcatggg aaagaagcat atagtatcca atttttattt ttggaacgaa
     9901 aacaatggaa aaaacttgat tggctccttc atatgaacga agagatttca gaagaagaac
     9961 agcggttgat cgaaaccgat ctgcgacttc tgcttgcaga tcatccacct cagtatttgc
    10021 taggatatgc agatttttat gatcatcggt taaaggtaac tgaagcaaca ctgatccctc
    10081 gaccagaaac agaggagtta gtcgaatggt gtttagacga gacgcctggt gtaccgttag
    10141 aagtgataga tattgggaca gggactggag caattgctat tagtttgaaa gcagcaagaa
    10201 aaaattggca tatatctgct gtggatcttt cagaagaagc attagaagta gcgaaagaaa
    10261 atgctcagaa agaaggaacg aaaatcagtt tttatcatgg agatacatta ggaccagtaa
    10321 tggatcagca atttgatgtg attatttcta atccgccgta catcagtcgg aatgaatggg
    10381 aactgatgga tgaaagtgtc cggtcattcg aacctaaaat ggcccttttt gctgagaacg
    10441 atggattagc tatttatgaa aaaatagcag ttgaagcacc aagcgtacta aaatcaaatg
    10501 gaaagatttt tttagaaatc ggatttcgcc aaggtgaagc agtaaaaaaa atatttcagc
    10561 aagcatttcc agataaaaaa gtggcgataa aaaaggatct ttttggcaat gaacgaatga
    10621 tccaagttta tggttgaagt tgtggatgaa aaatttttta tttgtttttt tattataaaa
    10681 aaacacttat ttgacaagga tgtaaacgac tttttggttt atcaacaagt ttatccacta
    10741 ttgacaaata gattatccac aaacagtgga aaacttgagg ataaactcag acaaaataag
    10801 aatgtatgaa aaaggggttg tggataaact gtggaaacga aacgatatga tgaaacagaa
    10861 ttgcaagagg cagccgaagc actgaaagaa ggagaacttg ttgcttttcc taccgaaaca
    10921 gtatacggat tgggcgccaa cgctctttta ccaaacgctg tcaagaaagt gttttctgta
    10981 aaagggagac cgcaagataa tccattaatc gtccatgtcg cctcttttga acaagtaaaa
    11041 gagtatgtgg acaactttca tccggcagca gagaagattg tgaagaactt ctggcctgga
    11101 ccattaactt tgatatttaa gatcaaaaaa gacactttgc cctcagttgt gacgggagga
    11161 ttatccacag ctgcatttcg tataccggat aacaaaaaaa cactagaagt aatcgaactt
    11221 tccggtgttc cgcttgtcgg tccaagtgca aatacgtcgg gaaaaccaag tccaacgact
    11281 gcagatcatg tatatcatga tctacaagga aaaattaccg ggattattga tgatggagct
    11341 acgcgaattg gtgtagaatc cactgttctt gatttaagtg atccaacagc catgcctatg
    11401 attttacgac caggtgcagt aacgaaagaa caaatcgaag cagtcatcga atctcctgtt
    11461 gctattgatc agcatcttgt aaaagaaaat gaaacaccaa aagcccctgg gatgaaatac
    11521 aaacactact cacccgatac acgtgttctg atggtcagag atggcgattg gtcaactgca
    11581 gttcaatggg caaaaaataa gaagatccgt gcaggtgtca tagcaagccc cgaaattgcg
    11641 gatcaagtgc ggacagatac tgcagctgtt tatatgtata acgacaactc agtagaagcg
    11701 gcggctaaag gattgtttgc aggtctaaga ggattagatg aaccaacact tggattagat
    11761 ttgatttttg tacaagtgta tccagaaact ggattgggga atgcttacat gaatcgcttg
    11821 aaaaaagcag caggacaaaa ttattttgaa aaatgatcaa ttggttattg tcgcattctt
    11881 ttagtatgat acaatgctat caagtaaatc ttctatcagt gaacgaaaaa ctaagcgtaa
    11941 ctaatcgtaa tagaagagat acgaatattt ggcaatttgt ttttgatggg aaaaataaaa
    12001 ttgtaggaaa ataaaattgt aggaaaataa aaaggagctg ttgtttgtgg tagattacaa
    12061 aacgtttgac cctgatcttt gggctgcgat cgccaaagaa gaagaaagac aagaacataa
    12121 tttggagctg attgcctctg aaaactttgt ctccgaagca gtgatggctg cacaaggaag
    12181 tatcttgaca aataaatacg cagaaggtta tccagggcat cgctattatg gtgggtgtga
    12241 atttgtcgat atcgttgaaa atttagcgat tgaccgtgca aaagaattat tcggagcgaa
    12301 atttgcgaac gtccagcctc actccggctc tcaagccaac acggctgctt atctcgcttt
    12361 ggtagaacca ggggacacga tcttaggaat ggatctttcc gcaggcggac atctaacaca
    12421 tggatcacca gtcaacttca gtggcaaaac ctatcacttt gttgcttacg gtgttgatcc
    12481 gacaacagaa gttattgatt ataatgtggt acgtatttta gctagaaaac atcaaccaaa
    12541 attgatcgta gcaggtgcca gtgcttacgg acgaacgatc gactttgcga aattcagaga
    12601 aatcgcagat gaagtaggcg caaaactgat ggtagatatg gcacatatcg caggattagt
    12661 agcagcagga cttcatccta atccagttcc ttatgcagat atcacaacga ctaccactca
    12721 taaaacattg cgtggccctc gaggcggcat gattttgaca aacgatgaag cattagcaaa
    12781 aaaaataaat agtgcggtat ttcctggtat tcaaggcggc cctctagagc atgtgattgc
    12841 gggtaaagca gtagcattca aagaagcatt agatcctgca tttaaagaat atagtgaaca
    12901 aatcatcgcc aatgcaaaag caatggtcaa agttttcaat caagcaattg gaaccagagt
    12961 catttcaggg gcgacagata atcatctgat gttgatcgat gttcgcgagt taggtataaa
    13021 tggaaaagaa gcagagagca ttttggacag tgtgaatatc actgtaaata aaaactcgat
    13081 tccttttgaa acactaagtc cattcaaaac aagcggtatt cgaatcggca cgccagcaat
    13141 cactactcgc gggttcaaag aagaagatgc tgtaaaagtg gctgaactag ttgtcaaagc
    13201 attacaagca aaagatgata acgctcaact agacgaagtc aaaacaggtg tacgcgaatt
    13261 aactgaaaaa tttccgttgc ataaaaaata aaaatttaaa ttccattagt aaacagaaaa
    13321 gttcaatgtt gggcttttct gtttattttt tgggaaaacg gattctttga caatatcggt
    13381 gatgctctct agtatatgag gtgtaatttt agtcttcaca ctaaatctca gggaggaaaa
    13441 gtcatgactg atcgtatctc gttagaaaag gaagcagtag cattcagtga tgcaaatgcg
    13501 cctcatccgc gtatctatga actagcaccg gaagaaggaa gagttttact agaagaagta
    13561 caagaatcac ctgtgaacaa atattccgtc gatattgaag acttgatggt ggatactggc
    13621 gaatggggaa aactcaatat tcgtctcgta cgaccagaag ggaatatgga taaattacca
    13681 gttatttttt atattcatgg agcaggctgg gtttttggca gtgctcaaac ccatgataaa
    13741 ttgatcagag aacttgcggt tcgtacgaat tccgtcgttg tctttccaga atatagtcga
    13801 tcaccagaag caaaatatcc aacagcaatt gaacaaaatt atgctgtgtt gcaacagctg
    13861 aataaattag ccaagtcaaa aaatctggat ctcgagaatc taatcgttgc aggagattca
    13921 gtaggtggta acatggctac agtcatgacg atcttaacaa aagaacgaaa gggcctccca
    13981 atatccaagc aattgctgta ttatccagtc acaaacgctg attttgatac agattcctat
    14041 catgaattcg gagaaaacta ttttttgaca agagaaggaa tgatgtggtt ttgggaccaa
    14101 tatacgacga atgaagaaga gcgtgctgaa atcacagctt cgcctttgag agcaaatata
    14161 aatgaactaa atgatcttcc ttcagcaatg attttaacgg gagaagcgga tgtattaaga
    14221 gatgaaggtg aggcttatgc gcgcaaactt cgtgatgcag gggttcctgt tacacaagta
    14281 cgcttccaag gaatcatcca tgattttgtc atggtaaatg ctatggatca gacaaaggca
    14341 acgcgtgcag caatggcatt atctacttct tggatcaaga aaaaagaata agctttgctt
    14401 gtccgcagga aaacttcttt tcaaaaacgg attttcttag gaaaaatggc gagtttgact
    14461 agtcaatcac ttgattttgt tttacaatta aaaagaaacg acagaacaaa ggagagctta
    14521 aaaaatgggc aaatttcaag tgatcgatca tccattgatt caacacaaac taactattat
    14581 tcgggacaaa aactgcggaa caaaggtttt tcgtgaagta gtcgatgaaa tcgctatgtt
    14641 gatggcatat gaagtatcac gggatatgcc attggaagac atcgtgatcg aaacaccgat
    14701 cactgaaaca acacaaaaaa cgttgtctgg taaaaaagta gcgattattc caatcttgcg
    14761 cgcaggtatt ggaatggttg acggtatctt ggaattgatt ccagctgcta aagtgggaca
    14821 tatcggtctt tatcgagatg aagaaacatt ggaaccacat gaatatttcg tcaaacttcc
    14881 agaagacatt gatgcacgtc agttgtttgt agtagatcca atgttggcaa caggcggatc
    14941 agcaatcatg gcaatcgatg cattgaaaga acgtggcgcg tcgaacatta aatttgtttg
    15001 tttggtagca gcacctgagg gagtaaaagc tttgcaagaa gcgcatcctg atattgacat
    15061 ctatacagct tctctagatg aaaaattgaa tgaacatggt tatatcgttc ctggactagg
    15121 ggatgcgggt gaccgtttgt ttggtacaaa ataagtaaat acgaaaaagg gtgtgacaca
    15181 acttttgtca catccttttt tggtcatttt taacgtttga tgcagaacag ctttttcaca
    15241 gctttcgttt gcatataaaa aaaccatccc aaaaatgcag agatggtcaa attcaaatct
    15301 tttttagttc tttgtagtta acgattacta cacccttact ttgcgtcatc aagttcgcat
    15361 tttctgcagt ttcatcaatc tcaacaacag cggaattttt caattgcttt gaaatcgttc
    15421 cagtttgcga cttgccgtga attgtgaaca ttacgtgagt attgatcttg aatttttcac
    15481 caatttccga tggtacgata gttgtatcaa attttccaaa agttgccatt ttcataaaac
    15541 ctgcctttca catcaattat accacgtttt atgaaaaata tcatgaaatt aaactaattt
    15601 tccatcggac tctttacaat cagccaaata gagtatataa tttcttttgg ataaggccag
    15661 cttagctcag ttggtagagc aacgcactcg taacgcgtag gtcgtaggtt cgatccctat
    15721 agctggcatt aaaagagaag acagatatat caaggatttt taatccattg atacatctgt
    15781 ctttttgttt aaaggaaata aagtatgctt tcttagcaat agagcatgta ttatttctat
    15841 aaaaatttag gagaataaaa cgactagcaa tatagctgtg aaatcaaata tcacatgaac
    15901 tgcccaactt gtaatgatcg agttgctttt aatggcagct tggttgaata acaatcttgc
    15961 caccccttgt atcaaaagga tgtgtgctac agtgtgtaaa atatttccat tatcataagt
    16021 actgtaatgg ataaatccaa agatgattgc tgacaagaaa ctagcgacag gaatgctgaa
    16081 cttactagaa aaaatagcga gaaaatacac tgagaacaat tcttctccaa gtatcatgat
    16141 aggcaaaata ataaataata acgggctgaa agcctcattt attggattgc ctgttaaacc
    16201 ccatttcaaa atttgttgca aaaataccga gactgcggca ctgattacta cattgataaa
    16261 aaaatatttg gctatatttt tgacaggagc gacaggtttc gagaacattt ttttcgtatc
    16321 ttttttacca aaaacaagtg taaatgctat aaatccagtg atagttaaag aaaaaatgct
    16381 aataatggat ggcgcaaata gcaaccctaa caaaccgagt acaacgacaa tagtgcccaa
    16441 tatccctttt ttaagttcta ttttttttcc taaaatgtta ttcatgataa taactcctac
    16501 tattcag
//
LOCUS       DAZUJR010000065        16392 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.065, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000065 DAZUJR010000000
VERSION     DAZUJR010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16392
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.065"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(51..1598)
                     /locus_tag="ACG804_002053"
     CDS             complement(51..1598)
                     /locus_tag="ACG804_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HFS4832975.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="ACG804_002054"
     CDS             complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="ACG804_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HFS4832976.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(2043..2237)
                     /locus_tag="ACG804_002055"
     CDS             complement(2043..2237)
                     /locus_tag="ACG804_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832977.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
     gene            complement(2463..3665)
                     /locus_tag="ACG804_002056"
     CDS             complement(2463..3665)
                     /locus_tag="ACG804_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4832978.1"
                     /translation="MKTKYPCVYQDKNGRFSYLVELGTDQVTGKRIQKKGTKDSLGKR
                     FSSAREAHKEVMRIKNEYMVVNGFANYDLTYKEFMEQSYVPHYKASVQKSTWSSRECG
                     LIQITEFFGDKKLREINVRDCENYRIWLLNDSGYSQAYSSLMYGMFRKSLDYAVTLQF
                     LNENISKRTKAIPKGKSIVPYWTKEEFEEVLAKIYKDDFYEHMCFLMIWLYYMTGVRV
                     SEGLALNWNDVDFKRKKLRVHHTLEMTNQKDFIRKPYTKTESGLRIISLDDDTIEVLK
                     KWKVIQKNHGVEQFILSYTDLPLYRSTVQRIIQRYAKLAKVPLIQGKGLRHSHVSYLI
                     NEFNADILVVSQRLGHSSPEITLKHYAHLWSRNDEGIAEQMTGNIKFTCATKSKVANF
                     NGNQAVKI"
     gene            complement(3668..3862)
                     /locus_tag="ACG804_002057"
     CDS             complement(3668..3862)
                     /locus_tag="ACG804_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HFS4832979.1"
                     /translation="MKNTICRKDLEALGFKTHQATTIIRQAKTRMVNQGYPYYNNKRV
                     GVVPRQVIEEIIGVPLSQEE"
     gene            complement(3909..4757)
                     /locus_tag="ACG804_002058"
     CDS             complement(3909..4757)
                     /locus_tag="ACG804_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HFS4832980.1"
                     /translation="MQAYNQKIIETPTYIEIYDYEAIITPKRKTIENEVNLERKQKLA
                     WIYENDITLEKRKNYDELSAQGQYDSLKRKQKHYQSMRFEIARLVDTNFDNQTKFLTL
                     TFKENIQDIEYANNEFKKFIKRLNYDLYKTKKANLKYLATWEKQQRGAIHYHIILFDF
                     PFISFNRLTTIWGQGFVKINKIDVDSIENRGRYISKYFDKELELKEHKKKAFFKSRNL
                     KLPTVTKKMVKKPYDSTNQDILYTSEYIVRRPFFYNALALNELGSPEQVMDFQESTVH
                     YTKIKK"
     gene            complement(4962..5312)
                     /locus_tag="ACG804_002059"
     CDS             complement(4962..5312)
                     /locus_tag="ACG804_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4832981.1"
                     /translation="MPIKITDLSLPKETLEKEYQVVNVTRWQKEGEILGWSYECILPK
                     LRYEKISVKVKSEHPVITPEELTQQGLAIITFTNLVIVPWGRSNGQFVSYGLSATADT
                     ATLIPRKQGTTTQN"
     gene            5490..6353
                     /locus_tag="ACG804_002060"
     CDS             5490..6353
                     /locus_tag="ACG804_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4832982.1"
                     /translation="MFGLVQPNKVKVGQRIKEIKDGMSLSFTELGNRLGLKKPTISSY
                     VQGYALAPKSVINQLSSISGKPVGWFYFGHVEEYIREYLFLIGQKKIVDDYPEIIEKI
                     KQEFYTGEFKNPAWENELGYPLEEFIQECFVEYSSEIMKDYVVQITKEVLEESKTLNK
                     LSSKAKEEAVTILSSGIIDYIEMSGEIKYGEKDRIAKMVKESIKTFDVKQDLTFNDSY
                     LIGKLINILGTDEDTELFLSSLSMIFTDKHFSTRFGGEELVEIFQSMRPALIKLYREK
                     TPDEFYDWFEK"
     gene            6977..7969
                     /locus_tag="ACG804_002061"
     CDS             6977..7969
                     /locus_tag="ACG804_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4832983.1"
                     /translation="MYWEEIELEKTLGPGGEIRAVQRDKKNISKWEKLKKQLRRDKWM
                     YLLLLPGIIMTFIFKYVPMYGAVIAFKDYNPMLGILESPWVGLDHFREFISSPNFTLL
                     LSNTLKISIYGLLLGFFPPIILALSLNQIINKKIKQKIQLILYAPNFISVVIIVGMLF
                     LFLSANGPINGLVEKVTGQPIMFMSNPAYFRTIYILSGIWQGIGWSSILYTATLAGVS
                     TDLYEAANIDGANILQKIWHIDLPALRPVMVISFILAAGGIMNVGYEKAYLMQTSMNI
                     PASEIISTYVYKVGLQSGDYAYSAAVGLFNMIINVVLLLIVNNITKRLNDGQGL"
     gene            7985..8869
                     /locus_tag="ACG804_002062"
     CDS             7985..8869
                     /locus_tag="ACG804_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4832984.1"
                     /translation="MNSALSKIDRQILWLNRVIVTFLVVITIVPLIYVLVASFMDPAT
                     LINKGISFNPKDWTIQGYQRVFADDSILRGFVNSLFYSFSFSLLTVFITMITAYPLSR
                     PNLAGKKIIMTFFVITMFVGGGLIPTYLLVKNLGMLDSVWAIIVPGAINVWNIILART
                     YFSALPKELSEAATIDGANDLQILFKVMLPLAKPIMFVLFLYAFVGQWNSYFDAMIYI
                     KDPDLQPLQLVLRNILIQNQPSQDMVGANTAMAEMKQIAELIKYATIVISSLPLIIMY
                     PFFQKYFDKGVLVGSVKG"
     gene            8918..10525
                     /locus_tag="ACG804_002063"
     CDS             8918..10525
                     /locus_tag="ACG804_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFS4832985.1"
                     /translation="MKAKWMLPIVFTSVLILGACGGSKEKSKSSPDYELENVSFPLKE
                     KVSLKMMSQSAPLAPNDPNDKLIFQRLEEETNLHIDWTNYSSDFAEKRNLDIASGDLP
                     DAIFNAAAGDYDLLNWAESGVIVPIEDLIEDYMPNLKKIFDENPEYRQMSTAPDGHIY
                     SMPWIEELGEGKESIHTVNGMAWINKEWLDNLGLEMPQTTDQLMTVLEAFKTQDPNGN
                     GEADEIPFSFINNGGNEDLKFLMGAFGLGDNDDHLVVDNDGQVQFTANKEGYKEAIKY
                     FNEMNNKGLIDKEAFEQDWNTYVAKGKEHKYGVYFTWDKANITGADDSYDVLPVLAGP
                     DGTKHVTRTNGMGFSRDRFVITSANKNLELTARWIDKMYEPLQSVQNNWGTYGDEAQA
                     NIFELKDGMLKHLPLEGTAPGELRQKTEAGGPLAVLDSYYGTVTTMPDDAKWRLDLMH
                     DTYLPYITEDNIYPRVFLEKEETDRLAKIETDMWDYIYRKRAEWITGGKIDEEWEEYL
                     AELERVGLEEWIQIKQTGYDNFLKGAQ"
     gene            10526..12010
                     /locus_tag="ACG804_002064"
     CDS             10526..12010
                     /locus_tag="ACG804_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016621147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HFS4832986.1"
                     /translation="MLVEETAILDKANRFIEMMRGKVNPQYRQNYHFSAPIGWINDPN
                     GFIYYKGHYHLFYQYYPYDSRWGPMHWGHARSSDLVHWEDLPVALAPDQPYDSGGCFS
                     GSAIERDGKLYLFYTGCQEIDGISHQHQCLAVSEDGIHFSKYSGNPVVAEKQLGENGL
                     IQEFRDPKVIVHNDGYYMVVATKSTQSTGRIVMFQSSDLYTWHFYSVLLEGTSEQGIM
                     WECPDLFHLDGRDVLIMSPIQIKKNGLEYHNISSTMACIGEVNWETGQMIVDNFHEMD
                     FGMDFYAPQTTRDPNGGRVMIAWMQMWDRTLPTHELGHLWAGSMSLPRELRVKKNRLV
                     QKPISTVYSHLVYQQGSENIAVTDTSVVFRNALSDSSYLHLVADLEKAEVFTIELLRS
                     KTDCLKLAYDTATQVFELDRQKLGRELTGAEEDPLNVRKVEVPLIDNQLVLEIFRDTS
                     SIEVFINGLEVMTATFYELEKARDILFHSIGESRIQAFETASVK"
     gene            12187..13179
                     /locus_tag="ACG804_002065"
     CDS             12187..13179
                     /locus_tag="ACG804_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005230454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4832987.1"
                     /translation="MKATMKDVAKLAGVGVGTVSRVLNNGSVKASTREKVEAAMTELN
                     YQPDFYARGLKMKHTNTVALILPTVWHPFFGEFAYHVETALERQNYKLYLCNSSGNSE
                     KEQEYIQMVSQNKVDGIIGITYSDIDEYISSNLPFVSIDRYFTEEVIYVTADNAAGGR
                     LAANELYRRGCQNVAYIGGYQETPNETKSRRKYFEIECRQLGISYKALDMLEPLDHLS
                     ERVTNFLLENPDIDGIFTINDPMALAVIDMLEKIGKNVPEDVQVIGFDGQKMTEGDPY
                     LVSTIAQPTKQMAEVAVAKLIAVINGETVEKRTVLPIEFGEGDTTKPLVRNDFA"
     gene            13231..14100
                     /locus_tag="ACG804_002066"
     CDS             13231..14100
                     /locus_tag="ACG804_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005472675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFS4832988.1"
                     /translation="MLYGGIEAGGTKFVCGIGNEQLQVIERKSFPTTTPEETMEQVFD
                     FFDKYKGNIASIGVGAFGPIDIQIESRTYGYITNTPKLAWQNYHFVGALENALSVPIY
                     WTTDVNAACYGEYMAGYGKGKNSVLYYTVGTGVGGGAVVDGKIVAGFSHPEMGHMLLQ
                     RHNEDQFEGICPFHHDCLEGLASGPAIEKRFGRKAQTISFDHPYWTIEADYLAQCVYN
                     TTLLYAPEVIILGGGVMKQPQLLELIRQSFKEKMGSYVDTPTLEEYLLTPRLADNAGL
                     IGCLALAIKKLNH"
     gene            complement(14520..16133)
                     /gene="guaA"
                     /locus_tag="ACG804_002067"
     CDS             complement(14520..16133)
                     /gene="guaA"
                     /locus_tag="ACG804_002067"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HFS4832989.1"
                     /translation="MRRTERAAYRTKFYSNLSSPTRFDEEPKIIVLDYGSQYNQLITR
                     RIREFGVFSELMSHRITAEEVKAMNPKGIILSGGPNSVYDEKAFGIDEKIFDLGIPVL
                     GICYGMQLITYKLGGKVKPAKNREYGKAELEITSAEAALFQNTPEKQTVWMSHGDLVT
                     QAPTDFDVVATSKDCPIASIQNAERKMYGIQFHAEVRHSEYGNDLLRHFTLDVCQCTG
                     DWTMDNFIDMEIAKIREQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHVL
                     LRKGEAEQVMESLGGKFGLNIIKVDAKERFLSKLAGVSDPEEKRKIIGNEFVYVFDDE
                     ATKLAGEEGVSFLAQGTLYTDVIESGTETAQTIKSHHNVGGLPEDMQFKLIEPLNTLF
                     KDEVRELGTQLGMPDSIVWRQPFPGPGLGIRVLGELTEEKLEIVRESDAILREEIANA
                     GLDRDIWQYFTVLPGIRSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKI
                     SVRIVNEVAHVNRIVYDITSKPPATVEWE"
     gene            complement(16140..>16392)
                     /locus_tag="ACG804_002068"
     CDS             complement(16140..>16392)
                     /locus_tag="ACG804_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFS4832990.1"
                     /translation="TEGFQETLKTISSTLPQSFKKKFTIFHRYQSGISNAFKVSHSNG
                     VTEGLNNKIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
BASE COUNT         4956 a         2866 c         3325 g         5245 t
ORIGIN      
        1 tacgtcaaat aacccgacct atagaataga atcgggaatg tttggcgttt ttagttacga
       61 gaaaaatgtt gttgtacatc cttgttccaa ggcaacagtt gatctaaagt ttctgctgaa
      121 agtacgggaa gatttggtat cttatcaaat agaaactcta gatactttac aggattcaat
      181 ccgttaagtt ctgctgtttt atatacactc agaatgattc ctgaagttcg tgctccttca
      241 agacttgtgg aatgcaacca atttttccgt cctatcacca gctctttgat atttcgctcc
      301 gcacgattat ttgtgagttc taaacgacca tcttcaaaaa taggttcaaa accacttcgt
      361 agtttacacg catattgaac ggctgcatcc aacttggatt ttgcaacagg atctatcgtt
      421 gccatccact cataaaaagc aataaataat ggacgcagtt cttgttgccg acagcttaat
      481 cgcttctcag gagaaaagtc tttccatttc ttttctagga caaaccattt atccaattgt
      541 ttgactgctt gagctgcggg aatatccgtg tttttctttc cttttggaat tgcttcgaaa
      601 aatttccgcc gaacatgcgc gaaacaatag acaagtcgta cactttccac ggcattatac
      661 ccgctatagc cgtcacagtg taaataccct gtaaactcct tgagaaaagt tttcggaaca
      721 tctccagcac gactttcgtc gtggtgataa taaacgatgg gatgctgact gtcttttcct
      781 gtacaaaact gccagtaata ggtatctgtt ttggcacttt caatcacacg ataacttgtt
      841 tcatccccgt gtagaatctc ttcttgatta agatagactc ttaatcgttc tcctaaaggg
      901 tctaacgcgt tttgcactgc tttaatatgc caattggtga tattatctct cgaaatatcc
      961 aacccatgtg tttgtttcca atagttctct tgccgatagg caggaacttt ctgaccaaat
     1021 ttcatccgga tcgtttccgc cactaaacta ttggaaccta agctattaga aatcaaaggt
     1081 ttaggaacga tcgctttttt aaaagaagaa agtccttctt tttcgcagct tttacaacaa
     1141 taggtatgtt gataatgggt gagacaatcc aacatagcct gatggaaacg aatttcttct
     1201 cgtacttttg tccgtccgat atctttcatc tgtgaaccgc aatgttcaca aaattgttct
     1261 tccaaaggaa ggagatgttc tttctctgtt ataggtaagt gtttgatttt gtctgctttc
     1321 gttcctacaa ctcgttgatg tccttttact ggaataatgg tggcagctgc ttctggaaca
     1381 cttacagaaa tttcttcatc actaaaaaga ttcaattgcc cattcgtttc ctcaaagaga
     1441 gtctctttag agcgtccaaa taatttgttg gttaaataat tgaccttttc attcaatagt
     1501 tggatttcag ttgtaagatt ctgaatggtt tgttgttgtg cttgattggt tttatgggct
     1561 tcttgaagca actgaagcaa cgtatctgta gtttccaaaa tttttcacca ccttgaatcg
     1621 aactgatttt gttacagaat accacaagaa acgcacaaga aataggggtt caacacattt
     1681 tttgtgttaa ccccccagct taaaaaactc ctttttttcc tggcaaaata gctcgaggtt
     1741 gatcgatact taatccttct aacaaccatc gaacctgttg gttcgttaag gttcgaactt
     1801 cgtctttcgt ccgaggccat tttaacttgc cgttttctat ccgcttataa cagagaagaa
     1861 aaccatcacc gtcccaatag agaagtttga aacggtcttg acggttcccg caaaataaaa
     1921 aaacggcatc ttcgtaaagc tcgagttgat actcttgttg aataagactg gcaagaccat
     1981 caattccttt tcgcaaatct gtttttccgc acacaatata aatatgtttg gtttgaagta
     2041 aatcataaag cattggacaa cagttctttc aaaatagctt gaagaatata attgttaata
     2101 ccgttataga tcaaaacttc agaaccattc tctcttttga tgcgcatcgc taacttggca
     2161 gccgcgggtt tacctttttc tggtgcactc ttttcgtttc ctaattggac aggaacaatc
     2221 tcatttaatt tatacataga aaacctccag acttcttgat agctcaagta tatcttgagg
     2281 tgcatttgtt agtaaggtac tgttctatgg ggcgcttacg ttgaaaaacg ttgatttatc
     2341 ggcattcccc atccatatta tatttacgtc ttattcccac tcaatatgag tagcctcgta
     2401 aagaagctat tatatcagtg ctttttcagc ctattcctca ttttggtagg gaaatggtag
     2461 ggttagattt ttactgcttg atttccatta aagtttgcaa ctttagattt tgttgcacag
     2521 gtaaatttaa tgtttcctgt catttgttct gcaattcctt catcattacg gctccataga
     2581 tgagcgtagt gctttaaagt gatttcaggg ctagaatggc ctaaccgttg cgacacgacc
     2641 agaatgtctg cgttaaactc attgattagg tagctaacat gagaatgacg taatcctttt
     2701 ccttgtatta ggggtacctt agctagtttg gcataacgct gaataattcg ttgaacagtt
     2761 gaacgataga gtgggaggtc agtgtagcta agaataaatt gttctacacc atgatttttt
     2821 tgaataactt tccacttttt tagcacttca attgtatcat cgtccagaga aatgatccgc
     2881 aagccgcttt cagtttttgt gtaaggtttc cgaataaaat ctttttgatt tgtcatttcc
     2941 aaggtgtgat gaaccctcaa ctttttacgt ttgaagtcca cgtcattcca attaagtgct
     3001 aatccttcgc ttacacgaac accagtcatg taatatagcc agatcattaa aaaacacata
     3061 tgttcgtaga aatcatcttt ataaattttt gccaaaactt cttcaaattc ttcttttgtc
     3121 cagtaaggaa cgattgattt tccttttgga attgcttttg ttcttttgga aatattctca
     3181 ttcagaaatt gcagggtgac cgcatagtct aatgatttac gaaacatacc gtacataagt
     3241 gaactgtatg cttgtgagta tccgctatcg ttcaataacc aaattcgata attttcacaa
     3301 tctcgcacat tgatttcacg aagcttctta tcaccgaaaa attcagtaat ctgaatcaat
     3361 ccacactcac gagaactcca agtacttttt tgtacgctag ctttgtagtg tggaacgtaa
     3421 gactgctcca taaattcttt gtaagttaaa tcataattcg caaatccatt tacaaccatg
     3481 tattcatttt ttatacgcat gacttctttg tgtgcttcac gagctgatga gaatcgtttt
     3541 cctagagaat cttttgttcc tttcttctgg atcctctttc cagtcacttg atctgttcct
     3601 aactcaacta gataagaaaa gcgaccattt ttatcttgat acacacaagg gtattttgtt
     3661 ttcatagtta ttcctcctgt gaaagaggaa cacctataat ttcttcaatt acttgtcggg
     3721 gtactacccc aactctttta ttattataat atggatatcc ctgatttacc attcttgttt
     3781 ttgcttgtcg gattattgtg gtagcttgat gtgttttaaa tcctagagcc tctaaatctt
     3841 ttcgacaaat tgtatttttc attgtataaa ctcactttca aagaaaacac tatcattggg
     3901 taatagtgtt atttctttat ttttgtataa tgaacggtac tttcttgaaa atccatcact
     3961 tgttcaggac ttcccaactc atttaaagct aaagcattgt aaaaaaatgg acgtctaact
     4021 atatattcgc ttgtatatag tatatcttga ttcgtggaat catagggttt ctttaccatc
     4081 tttttggtga cagttggtag tttgagattc cgggacttga aaaaagcttt tttcttatgc
     4141 tctttcaatt ccagctcttt atcgaaatat ttgctgatat agcgcccgcg attttcgata
     4201 ctgtctacat cgatcttgtt gatcttaacg aaaccctgac cccaaatcgt agttaaccgg
     4261 ttaaatgaga taaaggggaa atcaaacaag ataatatggt agtggattgc accgcgttgc
     4321 tgcttttccc acgtggcgag atactttaaa tttgcttttt tagttttata gaggtcataa
     4381 ttcagtcgtt tgataaattt tttaaattca ttatttgcat actcaatgtc ttgaatgttt
     4441 tctttgaaag tgagagttaa aaatttcgtt tgattgtcaa aattcgtgtc tacaaggcgg
     4501 gcaatctcaa atcgcatact ttgataatgt ttctgtttgc gttttaaact gtcatattgt
     4561 ccttgagcgg ataattcatc atagtttttt cttttttcaa gagtaatatc attttcataa
     4621 atccaagcta atttttgttt tcgttccaga tttacttcgt tttcgatcgt tttacgtttg
     4681 ggagtaatga ttgcttcata atcataaatt tcaatatacg tgggagtttc aatgattttc
     4741 tgattataag cttgcaaaaa tcatcactcc ttgttgcgta ttcgattgtc aaagaaccag
     4801 tcattttctc ctgatgttga tctataaatc aagttaaggg ggaaggcctg cgtagcagcc
     4861 cttctagcct atggggtgtt gggcggtctt aacggacaga aacggctctg tgggcgctgc
     4921 cccgccgttt cgtcctaacc acccaacact ccatagtata gttagttttg tgtagtggta
     4981 ccttgttttc tgggaatcaa agttgccgta tcagcggttg ccgataaccc ataactgaca
     5041 aattgtccat tcgagcgtcc ccaaggtaca atcaccaaat tggtaaatgt aattatggct
     5101 aaaccttgtt gggtaagttc ttccggcgtg atcacaggat gttcagattt gactttgaca
     5161 ctgatttttt cgtagcgaag ttttggtagg atacattcgt agctccaacc tagaatttcg
     5221 ccctcctttt gccagcgagt gacattgacg acttggtatt ctttttcgag tgtttctttt
     5281 ggtaaactga gatcggtaat ttttattggc atcacaattc tcctttttta tacgaaagtt
     5341 tatacgattt gattaaaaaa tatagatggc catctacgac ttgtattata tacgagaact
     5401 tatacgtagt caagagattt tctaaaaaaa tatatacgat tttttatacg agtgttataa
     5461 tgaaaaaaat gataaggagg aatttgaata tgtttggttt agtacaacct aataaagtga
     5521 aggtgggcca acgaatcaaa gaaataaaag acggaatgtc tctctctttt acagaattag
     5581 ggaatcgatt aggtttaaaa aagccgacga tcagttccta cgttcaaggc tatgcgttgg
     5641 ctcctaagag tgtgatcaac caattatcta gtatcagcgg aaaacctgtc ggctggtttt
     5701 attttgggca tgtggaagaa tatatccgag agtatttgtt tctcattggt cagaaaaaaa
     5761 tagtggacga ttatcctgaa atcattgaga aaataaagca agaattttat acgggcgagt
     5821 tcaaaaatcc tgcttgggag aatgagctag gctatccttt ggaggaattt atccaagaat
     5881 gttttgtaga atattcgagt gaaatcatga aggactatgt cgtacagatt acgaaagagg
     5941 tacttgaaga atccaaaacg ctaaacaaac tatcatcaaa agcaaaagaa gaagctgtca
     6001 cgattctttc atctgggatc attgactata tcgagatgag tggtgagatc aagtatggag
     6061 agaaagatcg cattgcgaaa atggtgaaag aatcaataaa aacctttgat gtgaaacaag
     6121 acctgacatt taatgattcc tatttgattg gaaagttgat caatattctt ggtacagatg
     6181 aagatacgga gctgtttctt tcttctttat caatgatatt tactgataag catttttcca
     6241 ctcgatttgg tggggaagaa ttagtcgaaa tatttcaatc gatgcgacca gcgttaatca
     6301 aactctatcg ggagaaaaca ccagatgaat tttatgattg gtttgagaag taaaataaga
     6361 aaagtggctt agattacaag ttggtgaaaa aatttttttc agcataacat cagtaatcta
     6421 taaaggggtt gttgattata ctgtagaagt taagtactca agagattttt tgtacgtaaa
     6481 caaagcaaaa aagggtgcag tttcactaga aaatgtactc ttttttgtga tttttcttag
     6541 ttatagagtt tttttgaaac tttaaaaatg agaaaacata ttgattttaa agagtgtaga
     6601 catagcttct tttgctaaat agattaaact tactggtgag tggtcttgaa catactttta
     6661 aatcacattt tactgagttt tattggattt tataattcat tggaaacctc gtacttaatc
     6721 tgtttttatc tatcgactag aatctgtata tattccagct atcaatgagg ccgcagaaaa
     6781 gggtgcttaa aaataatctg ttgtttaaaa tattattatc agaatactta gatacaaaat
     6841 tctggcacaa agtaaaaaaa atattgactt aaaaaaatgg atatggtaat ctataaacga
     6901 aaatagtggt aacgtttcca aaatgcatct tcgttaaatt tttatttttt taaacgaaaa
     6961 tggaaacgtt tctaaaatgt attgggagga gattgaattg gaaaagacat tgggaccagg
     7021 tggtgagata agggcggtac aacgggataa aaaaaatatt tcgaagtggg aaaaattaaa
     7081 gaaacagttg cggcgtgata agtggatgta cttgttgctc ttaccaggta tcatcatgac
     7141 gtttatcttt aagtatgtgc caatgtacgg tgctgtgatt gcatttaaag actataatcc
     7201 tatgctagga attttggaaa gtccttgggt aggactagat cactttaggg aatttatcag
     7261 ttcaccaaat tttacgcttt tgctgagcaa cacattaaaa attagtattt atggtttatt
     7321 gttaggtttt tttccaccaa ttattttagc actgagcttg aatcaaatta tcaataaaaa
     7381 aataaaacag aaaatccagt tgattctata tgcgccgaat tttatctcag tagttattat
     7441 tgtggggatg ctgtttttgt tcctatccgc aaatggacct attaatgggt tagtagaaaa
     7501 ggttacgggg caaccaatta tgttcatgtc taatccagct tatttcagaa cgatttatat
     7561 tttatcggga atttggcaag gaatcggctg gtcatccatt ctttacaccg caacgctggc
     7621 gggagtcagt accgatttat atgaggcagc aaatatcgat ggggcaaata ttttacaaaa
     7681 gatttggcat atcgatttgc ctgcattgag gcctgtgatg gtgatcagct tcatcttggc
     7741 cgccggcggt attatgaatg taggatatga aaaagcctac ttgatgcaaa cttcaatgaa
     7801 catccctgcc tcagaaatca tttccactta tgtatacaaa gtcggcttgc aatcaggtga
     7861 ttatgcctac tctgctgctg ttggtctgtt caatatgatt attaatgtcg ttttattact
     7921 gattgtcaac aatataacca agcggctaaa cgatggtcaa ggcttgtaat gaaaggagaa
     7981 aattatgaat agtgctttat caaaaatcga ccgtcaaatc ttatggttga atcgagtgat
     8041 tgtaactttt ttagtcgtca tcaccattgt tccgctgatt tatgtactgg tagcttcttt
     8101 tatggaccca gctactttga tcaataaagg tataagcttc aatccgaaag attggacaat
     8161 acagggatat caacgggtat ttgcagatga ttccatttta cgcggttttg taaattcgtt
     8221 gttttactct tttagcttca gcttattgac tgtatttatt acgatgatca ctgcgtatcc
     8281 tttgtctcga cctaacttgg cggggaaaaa gattattatg actttttttg tcattacaat
     8341 gttcgtgggt ggtggcttga tacctaccta tttattggta aagaacttgg gcatgttaga
     8401 tagtgtatgg gcgattatcg taccaggtgc tataaatgtg tggaatatta tcttagcccg
     8461 tacctatttt agtgctttgc caaaagaact ttctgaagct gctactatcg atggcgccaa
     8521 tgacttgcaa atactgttca aagtcatgct tccattagcg aaaccaatta tgttcgtatt
     8581 gtttttatat gcctttgttg ggcaatggaa ctcatacttt gatgccatga tttacatcaa
     8641 agatcccgac ttacagccgt tgcaactcgt attaagaaat attttgatcc aaaaccaacc
     8701 ttcacaagac atggtgggag ccaatactgc catggcagaa atgaaacaaa ttgctgagtt
     8761 gatcaaatac gcaacgatcg tcatttctag tctgccatta atcataatgt atcctttctt
     8821 ccaaaaatat tttgataaag gtgttttagt tggttctgtt aaagggtaag tattgttcac
     8881 tatttgtatg aataaaaatt ataaaggaga ttttaagatg aaagcaaaat ggatgctgcc
     8941 aatcgttttt acttccgtac taattttggg ggcttgtgga ggctcaaaag aaaagagtaa
     9001 atcaagccct gattatgaac tagaaaatgt ctcttttcca ttgaaagaaa aagtatcttt
     9061 aaaaatgatg tctcaaagtg cccctttggc tcccaatgat cctaatgaca aattgatttt
     9121 ccaacgatta gaagaagaga ccaatctcca tattgattgg acaaactaca gtagtgattt
     9181 tgccgaaaaa agaaatttgg atatcgctag tggtgattta ccagatgcca tcttcaacgc
     9241 cgctgcaggt gactatgatt tattaaactg ggcggaaagt ggcgttattg taccgattga
     9301 agatttgatc gaagattata tgccaaatct gaagaaaatt tttgatgaaa accccgaata
     9361 ccgacaaatg tctactgcac ctgatggtca catttactct atgccttgga ttgaagaatt
     9421 aggcgaagga aaagagtcga ttcatacagt aaatgggatg gcttggatca acaaggagtg
     9481 gttggataat ttgggtcttg aaatgccgca aaccactgat cagttgatga ctgtgttgga
     9541 ggctttcaag acgcaagatc caaatggtaa tggtgaagca gatgaaattc cttttagctt
     9601 tattaacaat ggaggaaacg aagacttaaa atttttaatg ggggcattcg gtctaggtga
     9661 taatgatgac cacttagtcg ttgataacga tggtcaggta caatttactg ctaacaaaga
     9721 agggtataaa gaagccatca aatatttcaa tgaaatgaat aataaaggtc ttattgataa
     9781 agaggctttc gaacaagatt ggaatacgta tgttgccaaa gggaaagaac ataagtatgg
     9841 cgtgtacttt acttgggata aagcaaatat cacgggtgca gatgatagtt atgacgtctt
     9901 gccagtctta gcgggaccag atggaacgaa acatgttact cgtacgaatg gcatgggttt
     9961 ctcaagagat cgtttcgtaa ttactagtgc gaataaaaac ttggaactta cagctaggtg
    10021 gatagataaa atgtatgaac cgttacagtc tgtccaaaat aactggggaa cctacggtga
    10081 tgaagcacag gcgaatattt ttgaattaaa ggatggtatg ttaaaacatt tgcctttaga
    10141 ggggacagca ccgggggaac taagacaaaa aaccgaagct ggaggaccat tagcagttct
    10201 tgattcttat tacggcacag tcactactat gccagatgat gcgaagtggc gtttagattt
    10261 gatgcatgac acgtatttgc catatattac agaagacaat atctatccac gtgtcttttt
    10321 agaaaaagaa gaaacagatc gattagcaaa aatcgaaacg gatatgtggg attacatcta
    10381 tcgcaaaaga gcagagtgga tcaccggcgg taaaatcgat gaagaatggg aagaatacct
    10441 tgctgaattg gaacgtgtag gtttggaaga atggattcaa ataaaacaaa ctggctatga
    10501 taattttttg aagggagcac aataagtgtt agtagaagaa acggcgattt tggataaagc
    10561 aaatcgattt attgaaatga tgcgaggaaa agttaaccct cagtatcgac aaaactatca
    10621 tttttccgca cccatcgggt ggataaatga ccccaatggg tttatatatt acaaagggca
    10681 ttaccatctc ttctatcaat actatcctta cgatagtcga tgggggccca tgcattgggg
    10741 gcatgcgcgc agtagtgatt tggtccattg ggaagatcta ccagtagcgt tagccccaga
    10801 tcaaccttat gacagcggcg ggtgtttctc aggaagtgca attgaaagag acggaaaact
    10861 atatttattt tatacaggct gtcaagaaat tgatggtatt agccatcagc atcaatgttt
    10921 ggcggtctct gaagatggta ttcattttag caaatacagt ggtaatcctg tggtagcaga
    10981 aaaacagcta ggtgaaaatg ggctaataca agaatttcgt gatcctaaag taattgttca
    11041 caacgatggt tactatatgg tagtagctac taaatctaca cagtctactg gtagaatagt
    11101 gatgtttcaa tcgtcagatt tgtatacttg gcacttttac tctgtgctgc tagaagggac
    11161 ttcagagcaa ggaataatgt gggaatgtcc tgatttattc catttagacg gacgagatgt
    11221 cttaatcatg tctccgatac aaatcaagaa gaacggactg gaatatcata atatcagttc
    11281 taccatggct tgtattggtg aggtaaactg ggaaacaggt cagatgatag ttgataattt
    11341 ccatgaaatg gattttggaa tggattttta tgcaccacaa acaacaagag atcctaatgg
    11401 tggacgggtg atgattgctt ggatgcagat gtgggatcgt acattgccta cacatgagtt
    11461 aggccatctt tgggcaggct ctatgagttt gccccgagag ttaagagtga aaaaaaatcg
    11521 attggtacaa aaacccatct caactgtata tagtcattta gtttatcaac aaggcagtga
    11581 aaatattgca gtgactgaca catcagtcgt atttcgaaac gcgctgtctg attcttcata
    11641 tttacatcta gtcgcagatt tggagaaagc tgaagttttt acaattgaat tactgcggtc
    11701 taagacggat tgtctcaaac tagcctatga cactgctaca caggtttttg aattggatcg
    11761 tcagaaacta ggaagagagc ttacaggggc ggaagaagac cctctgaatg tacgaaaagt
    11821 tgaagtacct ttgattgata atcagctcgt tcttgagatt tttagagata cctcatcaat
    11881 tgaagtcttt attaatgggt tagaagttat gacggctact ttctatgagc tggaaaaagc
    11941 tcgagatatc ttgtttcatt cgatcggaga aagtcgtatt caagcttttg aaacagcgag
    12001 tgtgaaataa atgtttgatt gcttaggcga tgaatcaatt atttaatagg ttttgaagga
    12061 taatgttttt agaaaagaac agatagctag atttcccatg gatttgctat tagtattttg
    12121 aaaaaattag taatttatga caaaattcat tatactaaac ttgtgcagaa atgtgaggga
    12181 tcaactatga aagcaacaat gaaagatgtc gcaaaattag caggtgttgg agtaggaact
    12241 gtttcccggg tattgaataa cggttctgtt aaagcttcta ctagagaaaa agttgaagca
    12301 gcaatgacag agttaaacta tcaaccagat ttttatgccc gggggttaaa gatgaagcat
    12361 acgaacacgg ttgctttgat tctacccacg gtatggcatc cattttttgg cgaatttgcc
    12421 taccatgtag aaacagcatt agaaagacaa aactacaagc tttatttgtg taactccagt
    12481 ggtaatagtg aaaaagaaca agaatatatc cagatggtca gccaaaataa agtagacggc
    12541 atcattggaa ttacttattc agatatcgat gaatacattt cgagtaatct gccttttgtt
    12601 agtattgacc gttatttcac tgaagaggtg atttatgtga ccgctgacaa tgcggccggt
    12661 ggacgtttgg ctgcaaatga actttatcgc cgaggatgtc agaatgtagc atatatcggt
    12721 gggtaccaag aaacaccgaa tgaaacgaag agtcgtcgaa aatattttga aatcgagtgc
    12781 cgtcaactgg ggatttccta taaagcgtta gatatgttag aacctttaga ccatctctca
    12841 gaacgtgtaa caaatttttt gttagagaat cccgatatcg atgggatttt tacgatcaac
    12901 gatccaatgg cattagctgt cattgatatg cttgaaaaaa tagggaaaaa cgtaccagag
    12961 gatgtccaag ttatcggatt tgatggtcaa aagatgacag aaggagatcc ttatctagtc
    13021 tcaacgattg cccaacctac aaagcaaatg gcggaagtgg cagtggcaaa attaattgct
    13081 gtcattaatg gagagacagt agaaaaacgt accgtattgc cgattgaatt tggcgaaggt
    13141 gacacaacga aacctttagt gagaaacgat tttgcttagt gcaaatacgt ttcttttttt
    13201 gaaaatgagt gaatgaaagg tgtagataaa atgttatatg gtggaataga agccggtgga
    13261 acaaagtttg tctgtgggat tggtaatgaa caattacaag tgatagaacg gaaaagtttt
    13321 cctaccacaa caccagaaga aacgatggag caagtgtttg atttctttga taagtacaaa
    13381 ggaaatatcg catcaattgg tgtaggagca tttgggccta ttgatattca aatcgaatca
    13441 agaacttacg gatatatcac caacacaccg aagttagctt ggcaaaatta tcattttgta
    13501 ggagctttgg aaaacgcctt gtcggttccc atctattgga ctaccgatgt aaatgctgct
    13561 tgttatggag aatatatggc agggtatgga aaaggtaaaa atagtgttct gtattacacc
    13621 gttggtacag gtgttggtgg tggtgctgta gtggatggga aaatagtcgc aggttttagt
    13681 catcctgaaa tgggacatat gctcttacaa cgtcataatg aagatcaatt tgaaggaatc
    13741 tgtccttttc atcatgattg tttggaaggg ttagcatcag gacctgcgat tgaaaaacgc
    13801 tttggaagaa aagcccagac tatctcattt gatcatcctt attggacgat tgaggcagat
    13861 tatcttgctc agtgtgtgta taacacaacg ttactatatg caccggaagt aataatttta
    13921 ggcgggggtg taatgaaaca gccgcaacta ctcgagttga ttcgccaatc gtttaaagaa
    13981 aaaatgggtt cctacgtgga tacgcctact ctcgaagaat atctactaac tccaaggctt
    14041 gctgacaatg cgggcttgat tggctgccta gctttagcaa taaagaaact caatcattag
    14101 aatagtattt attagaacta ttcataacat accggaagtt taaaagggta ttctgaaact
    14161 taaatagtct caattcattc ttctttcttg agaatctgag tagagacttt tattctgttt
    14221 caaattaata taattacgaa atgatattga gtacaagaaa gttcttttta ccagatcttt
    14281 taaatcgaaa aatctgatat atatatttat agtactaaaa atctgattag ataaaaagct
    14341 aattcaatag gaaaataaag gtagtgaata aaagcaaagc ccttgttagt agttaatcta
    14401 acaagggctt tggtagggaa aatggtagga aaccatctta ttttttacga aaatcaggaa
    14461 ctttagtaat tgaataatgt tgatttatag gtattcctca tccatattat gttggctctt
    14521 tattcccact ccactgttgc aggtggtttg ctggtaatat catacacgat acggttaacg
    14581 tgtgcgactt catttacgat acggacactg attttttgca agacttccca agggatacgg
    14641 gcaaagtcag cggtcatgcc gtcaatagaa gtgacagcac ggatacctac agtgtagtca
    14701 tacgtacggc catctcccat aaccccaaca gagcgaatgc ctggtaggac ggtgaagtat
    14761 tgccagatgt cgcgatctaa accggcattg gcgatttctt cgcgcaagat agcgtctgat
    14821 tcacggacga tttctaattt ttcttctgtc aattcaccaa ggacacgaat acctaagcct
    14881 ggtccaggga atggttggcg ccaaacgatg ctgtcaggca tgcctaattg ggtacctaat
    14941 tcacgtactt cgtctttgaa caatgtgttc aatggctcga tcagcttgaa ttgcatgtct
    15001 tcaggtaatc cacctacatt gtgatgtgat ttgatggttt gggcagtttc agttcctgat
    15061 tcgatcacat cggtataaag ggttccttgt gcaaggaaag aaacgccttc ttcaccggca
    15121 agtttggttg cttcatcatc gaagacatat acaaattcat ttccaatgat tttacgtttt
    15181 tcttctggat cagacacgcc agcaagtttt gataagaaac gttctttggc atcgactttt
    15241 ataatgttca agccaaattt tccgccaaga ctttccataa cttgttctgc ttcaccttta
    15301 cgcaacaata cgtgatcaac gaagatacat gttaattgat cgccgatcgc tttttgtaaa
    15361 agaacaccaa caacagagga atctactccg cctgaaaggc ctaataaaac ttttttgtca
    15421 ccgacttgtt cacgaatttt tgcgatctcc atgtcgatga agttatccat tgtccagtca
    15481 ccagtacatt ggcagacatc tagtgtaaaa tggcgcaaca agtcatttcc atattcggaa
    15541 tggcgaactt ctgcatggaa ttggattccg tacattttgc gttctgcatt ttggatcgat
    15601 gcgatggggc aatctttgct ggtagcaacg acatcgaaat cagtcggtgc ttgggtaact
    15661 aggtcaccat gactcatcca aacggtttgt ttttcaggag tgttttggaa aagggccgct
    15721 tctgcagaag tgatttccaa ttctgctttt ccgtattcac ggtttttggc tggtttaact
    15781 tttccgccta atttataagt aatcaactgc ataccgtaac agattcctaa aactgggatc
    15841 cccaaatcaa aaatcttttc atcaatacca aaggccttct catcataaac actgtttggt
    15901 ccgccagaaa ggatgattcc tttagggttc attgccttta cttcttctgc ggtaatgcgg
    15961 tggctcatca actctgagaa aacaccgaac tcacgaatac ggcgagtgat cagttggtta
    16021 tactgactac cgtaatcaag tacgataatt tttggctctt cgtcaaatcg tgttggtgaa
    16081 gacaaatttg aataaaactt agtccgatat gcggcgcgtt ctgtgcgccg catatttttt
    16141 tagttttcaa agatcagacc ttgttgtaaa tagatccgtg cccgaaagtt ataaaagttg
    16201 cgataaccaa acgcaattcg tttaatcagc ttgatcttgt tattcagccc ctcagtgacg
    16261 ccgtttgagt gggacacctt aaaggcattt gaaatacccg attggtagcg atggaagatc
    16321 gtgaatttct ttttaaacga ctgaggtaac gtagatgaaa ttgttttaag ggtttcttga
    16381 aagccttccg ta
//
LOCUS       DAZUJR010000066        16111 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.066, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000066 DAZUJR010000000
VERSION     DAZUJR010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16111)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16111)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16111
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.066"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..481)
                     /locus_tag="ACG804_002069"
     CDS             complement(<1..481)
                     /locus_tag="ACG804_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HFS4832991.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     "
     gene            complement(611..1321)
                     /gene="budA"
                     /locus_tag="ACG804_002070"
     CDS             complement(611..1321)
                     /gene="budA"
                     /locus_tag="ACG804_002070"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HFS4832992.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(1334..2998)
                     /gene="alsS"
                     /locus_tag="ACG804_002071"
     CDS             complement(1334..2998)
                     /gene="alsS"
                     /locus_tag="ACG804_002071"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003984 - acetolactate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0034077 - butanediol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HFS4832993.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(3203..3865)
                     /locus_tag="ACG804_002072"
     CDS             complement(3203..3865)
                     /locus_tag="ACG804_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFS4832994.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            complement(3875..4690)
                     /locus_tag="ACG804_002073"
     CDS             complement(3875..4690)
                     /locus_tag="ACG804_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4832995.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(4952..5395)
                     /locus_tag="ACG804_002074"
     CDS             complement(4952..5395)
                     /locus_tag="ACG804_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HFS4832996.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(5529..5867)
                     /locus_tag="ACG804_002075"
     CDS             complement(5529..5867)
                     /locus_tag="ACG804_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFS4832997.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(5855..6232)
                     /locus_tag="ACG804_002076"
     CDS             complement(5855..6232)
                     /locus_tag="ACG804_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFS4832998.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKKIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            6456..7649
                     /locus_tag="ACG804_002077"
     CDS             6456..7649
                     /locus_tag="ACG804_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4832999.1"
                     /translation="MTTYQRKLLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(7815..8237)
                     /locus_tag="ACG804_002078"
     CDS             complement(7815..8237)
                     /locus_tag="ACG804_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4833000.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            8608..9282
                     /locus_tag="ACG804_002079"
     CDS             8608..9282
                     /locus_tag="ACG804_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833001.1"
                     /translation="MKKLVALFLVAGSLLSGCGATTSTTQSTSSAQASSSSTTISEST
                     ADSSKEQEQIEKKKEEEKQKAEKAALEKKVTEAESALSQAEANPTKENYATASAAIQA
                     LPENKQELTSRLAAIDSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQQ
                     AAAEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPC
                     SKCYGN"
     gene            complement(9444..10616)
                     /locus_tag="ACG804_002080"
     CDS             complement(9444..10616)
                     /locus_tag="ACG804_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFS4833002.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(10822..12120)
                     /locus_tag="ACG804_002081"
     CDS             complement(10822..12120)
                     /locus_tag="ACG804_002081"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFS4833003.1"
                     /translation="MHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYP
                     SKDTAVPADATPFASVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLS
                     LPFYNPNSSDPDKPLDTIHLYAKNVIKESNIKIQKAGNFSGVDKLAGAQFQIKNSENQ
                     FVTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVETKAPDGYQLTNPQ
                     KETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNTITVENVQNYGDFHF
                     IKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWSDEVTGSDWEEVKL
                     ISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDDDPTTSDETTIDNQ
                     PKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            complement(12248..12763)
                     /locus_tag="ACG804_002082"
     CDS             complement(12248..12763)
                     /locus_tag="ACG804_002082"
                     /inference="COORDINATES: protein motif:HMM:NF037639.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prealbumin-like fold domain-containing protein"
                     /protein_id="HFS4833004.1"
                     /translation="MDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFT
                     SSKDGTFSVHGLSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEP
                     KANPTNNGKTPVQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKK
                     QQKGNNRREIK"
     gene            complement(12836..13750)
                     /locus_tag="ACG804_002083"
                     /pseudo
     CDS             complement(12836..13750)
                     /locus_tag="ACG804_002083"
                     /inference="COORDINATES: protein motif:HMM:NF027869.4"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
     gene            complement(13747..16074)
                     /locus_tag="ACG804_002084"
     CDS             complement(13747..16074)
                     /locus_tag="ACG804_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBG domain-containing protein"
                     /protein_id="HFS4833005.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSATETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
BASE COUNT         4598 a         3227 c         2856 g         5430 t
ORIGIN      
        1 aaaaagcatt tatattaaaa tttgctaata aaagatctac atatttttct agaaatgctt
       61 gatcgatttc atcataccct ttcgttactc cgcaatcgat atctaaaaca ccgattaaat
      121 taccttcttt taccattggc actacgattt ctgattgtgc ggctgaatcg caggaaatgt
      181 aatttgcatg ggttttgaca tcatcaacga tcaatgtttc ttgtttttca gctgattctc
      241 cacaaactcc ttttcccatc ttgatacgtg tgcaagaaac tcgcccttgg aacggtccta
      301 aaatcaattc attaccatcg aataaataat atcctgcaaa gacagtctca ggcaaagtct
      361 cattcaacaa tgcagatgaa tttgctaaat ttgctaacca gttatcttct gcttctaata
      421 atccttgttg ctgtaataat aaaatttcgt atgcatcttt tttctgtttt tctgtccaca
      481 tgataaaaac cgctcctttt tgatctatgg agaagattat agctcagttt ttttgtaaac
      541 gctaggtttt ctcctcaaaa aaacgagata cgtcaggtta atcaccttga acgcatctcg
      601 ctgtcttttt ctattctgct tgttggattt ctgctgctaa atcagcataa tcaatcgttt
      661 cgtgaacaaa agtcggatca tcaactggaa aatgctgtac aagggacgag atgcggctaa
      721 tctcaacttt tccttcagcc acttcaaaat ccattacatg tccgccaaat gtatgtgtat
      781 catcgataaa atgcaggtga aatcccgctg cagcaactcc ttggaataat tcaggcgtaa
      841 agaacccgac taatgttcct tggacattgc tttgttggaa ttctggttga gactctgaaa
      901 tttttgctag tcttctgtaa ggtttttctt gcttcggcat gatacggatg tgcatatttt
      961 tgaataatcc agttatcttc actgccaaaa ataggttttc cccggcttct cttactaata
     1021 tgtctttttt caattgttct ccatctgcag tttttgagac agaaaaacta gtatctggcg
     1081 taaaatctgt aattgctgca tagggggtaa gttcacttcc atctaattgg gcaactgagc
     1141 catctgatct tccttgataa gctacgccat ctaaaaagat gacttcacca tcaagcccat
     1201 gcaatgttcc caatcccaga gttccttttt ctaatatatg agcaatcgtt tctgttccat
     1261 ccatcaagcc agccatcaaa gctcctaatg tcccgtgctg gtataagatt ttttcagtca
     1321 tgtcgacact tccttaatag aattgatctg gtaagattgt ttctcccaat ttctcattat
     1381 cacggtaatc aatcggaata tcaataatta cgggtccttc tgtcgcaaat ccttcttcta
     1441 aagctttttc taattcctct acacttgtag ctcggattcc tttagcgcca aaagcttctg
     1501 catatttcac aaaatcaact ggaccaaagt ctacacctga cgcccgctga tatttcattt
     1561 tttcttggaa ctctaccata ttgtagtgtc catcattcca aatcaaatga acgatattca
     1621 attttttacg taccgccgtt tctaaatcct gggcagagaa taaaaatccc ccatcgccgg
     1681 aaactgatac gatttgtgta tttggacgca ccaatgcagc agaaatcgcc catggcaatg
     1741 caacaccaag cgtttgcata ccattactga ataacaaatg acgaggttca taacttctaa
     1801 agtggcgtgc catccaaata taatgactac ctacatctac ggtaacagtc atatcatctg
     1861 ttacttttga ctgaagcgtg ttaataactt ctaaaggatg caagatacct gcttctcctt
     1921 ttgattgaac aatgtcccgc tccgttaatt ctgcttgaag agatgctaaa tattcttttg
     1981 catcttctga cacttgttga ggctctaatg aacctgtcaa taaatcaaga gtggctgaga
     2041 tatcaccgat caattctctt tcaggctgca taaaaggatc gatttcagct ggcgcttcat
     2101 cgatcacaat gatccgcgca tctttttccg cattccagtt tcttgcttca tattcgattg
     2161 gatcatagcc aatagcaata actagatcac ttcgtttcaa aagcatatct cctggttggt
     2221 ttctaaataa acccacacga ccaaagaaat gcgcttctaa ttcacgtgag atcactccag
     2281 ctgcttggaa tgtctctaca acaggcaatg ctgtctttcc aactaattgc ctgatggcta
     2341 acgtttcttt ttcacttgat cctcgcatac ctactaatag taccggtagt tttgcttctc
     2401 taatgcgttc agctaggtaa cggatatcat ctgcagaagc agaacctaat ttaggatcgc
     2461 tcaatggctt gatgacattc ccttggacag gtgcatccac tacatcttgc gggatactga
     2521 taaagctcgc gccttttttt gaactcttag ccatacgata agcattggca atcacttctg
     2581 aaattgtttc tggatcttgg atttctgcac tgtattttgt gattggctgg aacagtgctg
     2641 cattatccat gctttgatgg gtcaacttca atagatcgct tcgttttact tgtccggcaa
     2701 ttgctaaaac tgggtcacct tctgctgtcg ctgttaccaa acctgtagct aagttactag
     2761 caccaggacc acttgttgcg ataactactc ctggctctcc tgtaatacgt ccgattgctt
     2821 gtgccataaa tgcagcattt tgttcgtgac gagtcacgat taattcagga ccttgatcct
     2881 ctaattcatt aaatacacca tcgatttttg cacctggtat accgaataca taatcaacat
     2941 gatgattaat caaactttct actacagatt tcgaaccttg tttcattttt tcgtccattg
     3001 aacatcgtcc tttttatgct ttatttttaa ttattagtta gaaataatca caaataattg
     3061 atacagtttc taaacctgtt tcattcaaaa gtatagcacg ttttatttca tttgtttagc
     3121 catatgtttc aaaaaatgaa aaagaatgac agtttttaca taaaaactgt cattcttaat
     3181 tgaaagtttc aatttataaa gtctacagat ccatagttct catcaattta cgattgttga
     3241 agtaaatcaa accaaatacg atagaaggac ctagtagaat acaccattgg ggctttacga
     3301 aaaagaagag aaacaaactt gtcaatagta aaaaatctag taaactcaca taccattttt
     3361 tcaacgtata gtagaacgct atccgtagaa cttgatttgg tttcgacgct ggatttctca
     3421 cctgaaaata ccagtagttg atgctaaagg aaactgataa acaagcaagt aaaacaaaca
     3481 acggaatcaa ccattttcca taagaaaaac gtataaaaaa gaaacaatca aaaatcatta
     3541 tcacactaac tatccaagca aatagccaat aaaaaaatcc ctttagccaa aattggcgaa
     3601 acgtctttat gaacaaacgt actggtgaaa aacttttttc ttttgctaat tcttctgtca
     3661 tacctatcat cacgatgcaa cctggaccaa taaaaagtaa agaaaaaata aaggaaaaga
     3721 cattccttcc atctatcgac aaaaggaacg cagctgctat atacaagata ttgacacacc
     3781 aaaaacaaag gctacttgcc aatgattgat acaaccaata aaagaattcc atataaacat
     3841 ttttgtcaaa acgctgctct ttcataatca cctcctattc cttcattcct gatgaagcga
     3901 tcccttctac aaaatatttt tgcatcgcta aaaatataaa agcaacagga agaacagaaa
     3961 caactgaggc agccatgatt aatgcgtact ctgcatcaaa tagcccaata aacattttca
     4021 accctaactg gattgtttta ttttccgtag aagacaaata aatgaatggc cccatataat
     4081 cgttccatgt attaacgaat gtgatgatcg tcaaactggc aatcgccggt tttgtaagag
     4141 gtaaaatgat cttgcgatag attccccact ctgataagcc atcgatccgc gcactctcac
     4201 ataaagaatc tgggatacta ctgtagtatt gcttcaacaa gaacacacca aaagcattga
     4261 acgcttgtaa tagcaccaac gaccacaacg tatatgttaa acccactttt ctcatcataa
     4321 tgaactgcgg gatcatataa gactgccaag ggacagcaat cgtgccgata tatgctaaaa
     4381 ataaaatatc gcgcccttta aaatttagtt tagaaaaccc gtaagcagca aaactagaag
     4441 taaacaactg aatcaacgtg atcacaacgc ttaaaaaagc tgtattctta aaaaatgtca
     4501 ctaaaggaat acgagaccaa ataaccagat aattctctaa atgccaagtt ttagggatcc
     4561 attgaatcgg aatcgtgaac acttcattat ttgctttgaa tgaagcagaa accatccata
     4621 aaaaaggaat gatcgtcaat aaagctaata caatcagcag aatcataccc aaccattgaa
     4681 taaagggcat gttttttgaa cgaatttttg ctttttttct ttcatttcga acacctccaa
     4741 agttataatc ttcatttctt tgtaatgatt acaatccaga acaacggtta ttatagctga
     4801 ttcatttccg ttcttcttat gtttgtaagc gcttatttaa caagttatgt aaatctcttt
     4861 attttttttg atttaaaaat gaaaaaatac aaaagcaaga ctgtcatacg tctcgctttt
     4921 gtattgaaat ttcttcgatt agagatactt attactgttc aaaagcttct ttgaaacggt
     4981 gaatcaattc attgactaca ggtgataaaa tccgattctt tttccagact agcatgcagt
     5041 tcgtttcaat cattgggtca agcggaacga atgtcactcg ctttgaaaga tgacttacag
     5101 caccttctat gactaaagca gcacctacct gattctcaat tagcgcaaat acattgaaaa
     5161 tcaaattgta cgttcctgtg atcagcaact gctccttttt tatgcctaac cagtcagcaa
     5221 acattcgctg tatttctgga cgctttgaga tcaaaagagg tacattcgca aagtcttctt
     5281 ttgttatcac gtcttttttt gctaaaacag aattttctaa aatgagcaat ccccattttt
     5341 cctttcttgg taacaaaatc gtttcgtatt tctctgtatc tactggatct agcaaaatcg
     5401 ctaaatctaa caggcttttt tctagtcact ccgtgatatc atcacttgtt ccgctgtgga
     5461 tatgaaattg aacgctggga taatcacgga tcaacttttc tagtaatagt gccaatgtat
     5521 tcgaattatc agcttccaca cagccgatcg taaatcggcc gctgaataat tgtttttttc
     5581 tgttctcgaa ttcttgagtg gtttgattcg ttaaatctaa aatttcttct gctcggcttt
     5641 tttagaaaat aacctgcttc tgtcaagatc attttgcggt tttcgcgtac aaacagttct
     5701 gttcctagtt cctcttctaa ctccttcagt tgtcggctta aggttggttg tgtaagatgt
     5761 agaacttctg cggcttgaga gattgttcct tcttctgcaa ttgtccaaaa atattttagt
     5821 aagcgtaact ccatagcgat gctccttgat ttttttactt gatacattcc attttatttc
     5881 tagataacac acgatcatat ttcttgattt ttccttgtaa acgttccaaa cattcttgca
     5941 tttcagcaat ttttttcgtc aaaagttcac tttcttcaat caaaagctta cgccgctcaa
     6001 atacagttgc ttctccttcg ctagataggc gaatatattc aatcaaagac tcgatcgata
     6061 atccggcatt tcgcatacag atcgtaaagt cgacccattt taggtcttct tctgtataat
     6121 cacggattcc gccttttgtc cgattaactg gtggaatcaa cccgattcgt tcataatagc
     6181 gcaatgtatc ggccgaaatg cccttttctt cactgacttg tttgatattc atctgatcac
     6241 tctttctctt aatttcttgc cactttactt atgtatttta tttattctac aactttaagt
     6301 gtactccaag tcaatactca tttctattaa aactaagctg gattatctat atcggttgtt
     6361 tgtgtattat ttcaaataaa aaagtcttgt ttttttattc ttttttggat atacttttaa
     6421 caatttaggg aaattttagg aaaaggggta taaaaatgac aacgtatcag cgaaagttat
     6481 tattatcgac atcggcggga attgctttag agaatatgga tattatgttt ttagcttttt
     6541 cattatcttc aatgattact tcttttcata ttagtggtac gcaagcgggt ttcatttcaa
     6601 cgatcactaa tttggggatg ctcattggag gtattttttt tggcatcata gctgataaat
     6661 atggacgtgt gaaagtattt tctcaaacgg tccttctgtt ttcgattgct tctttattga
     6721 tgtattttgc ttcaaacatc tacttggttt atctctttcg ctttatcgca ggtgtaggag
     6781 cgggaggaga atacggggcg tgtatgtcct tgatttccga aagtttttca aaaaaacaaa
     6841 ttggacgagc ttcttcggtt gctggtattg gtgcgcaggt cggtgcggct ttggctgcga
     6901 ttttagctgc tgtgatcatt ccaacgtttg gttggaagat gttgtatgtc gtaggtgtac
     6961 tgccggtgtt gatggtcttg ttcattcgtc gcggcttgac tgaaccaaag gaattcaaat
     7021 ctgtacaatc tgccgaaaag aaaaccaaac ttagcagact gtttgaatca aaacatcttg
     7081 cttggcaaac atgtggcctt agtatcatgg taactgtcca aattgccggc tattttgggt
     7141 taatgaattg gctgccttca attatgcaaa atcgattagg gctttcggtt tctgggtctt
     7201 cattgtggat ggtcagtact attttaggca tgtctttggg gatgatgact tttggcataa
     7261 tcatggataa attggggcct aaactagcct tttctttgtt tttaatttgt tcatccttat
     7321 ctgtctatct acttgtgtta gcccatagcc agtggagttt ggtagcagcc gctgtgatag
     7381 tcggctactt tatcaatggc atgtatggtg gatatggcgc agtgattagt agtttgtatc
     7441 caacagaaat ccgcgcgacg gcgaataatt tcattatgaa ccttggacga gctgttggtg
     7501 gtttttcttc tatcgtcatc ggtttcttga tggatcatta tagtttaact gccgtaatct
     7561 tgtttttgag cggtatttac ctagtcagtc tgctggtctt gacaactctt actggtgtta
     7621 cagcattaag ggaaagcttg cagcattgat agttgagtct gtaaatgaca agaaagaggt
     7681 gtggcaaaag cttgcatctg cggtaataag accagccaaa tcaaaaacat gagacactgt
     7741 ttccgtttgg ctggtcgtat tacttgatgc agggcagctt tttcaactgc taatttcctt
     7801 ctatctggcg gctactattc tttgacgtcc gtcatttcaa agtactttac taataactta
     7861 gcataacgaa aaactgtgga tacactcgta tattgagcgt ctgcataatc ttccaaattt
     7921 ttctcaggat gttgatacat gaattcaatc aaatgataat tatatgattt tctgtagaaa
     7981 tgaagataaa taatgtagat tgggaagttc tcctgctttt ccatagaaaa gcgccgatta
     8041 ttctcattct tcaaaatgac cttatcagga tatttttgga acaattcttc taaatctgtt
     8101 agataattca agatagactt acttgatacc ttcaattcgt tttgtagttc ttctattgaa
     8161 caccaacgtt ctgtttcaag cagtaaatga atcattttaa ttttcttttg agaaactttt
     8221 gttaaaaaag tctgcatatt ttctcctcct gtatctactt tactatacta catacaagaa
     8281 aaaaaacgga tacaaatatc atattgtcac accgtcaata gtgcataaac ctgttattat
     8341 ttctcttttt ttcctaagta ttctattgat atgaatcatt taatcgttta ttatataaat
     8401 gtcaataatc taataataaa ataacgtaca tattttatta ttgcatactt aataacagaa
     8461 ctatagcaaa aaatcccgtg tatcaaaacg ggattagatt aagtttcctc aatcactatt
     8521 cataacacaa ttattataac aagtaagtaa acaattgaaa aggacattta ttgaaaacgg
     8581 ttgtttttta cttaaggagg aaatttagtg aaaaaattag ttgcattgtt tttggtcgca
     8641 ggaagtttgt tgagtgggtg tggtgctact acgtctacta ctcaaagcac aagttcagct
     8701 caggcttcca gcagcagtac cacgatctcc gaaagtacgg cagattcatc gaaagaacaa
     8761 gaacaaattg aaaagaaaaa agaagaagag aaacaaaaag cggaaaaagc tgcactagaa
     8821 aaaaaagtga cagaagcgga atctgctttg tcacaagctg aagcaaatcc tacaaaagaa
     8881 aactatgcaa ctgcttcagc agctatccaa gcgctacctg aaaacaaaca agagttgaca
     8941 agccgtcttg ctgcaattga ttccacaatc aaagcaaaag aagcagaaga agaacggaaa
     9001 aagcaagaag aaattgcacg acaacaagca gaacaagcgc aacaagaagc aatcgcacag
     9061 caacaagcag aacaggcgcg acagcaagca gcagctgaac aggcctctca gcaggcacaa
     9121 gccgcagctc ctgagcaaaa taatgaacaa actgtctatg tcacaccgac cggttcaaaa
     9181 taccatacac ataaatgtgg aaatggtacg tatacccctg ccactttaag cgaagctcaa
     9241 gctcgtggtt taaccccttg ctccaaatgt tatggaaact aattcaaaag ttatactata
     9301 ataataaaat tcttctgaaa cataaaaaaa tagaagctgg cgttccagat agtaaaccaa
     9361 aaatagcagt ttacacgtcc atttcgtcag cttctctctt ttttcattta gtctgttccc
     9421 tctgcttttt tggacatctt cattcattct ttctcaatca aatagtacac ctctttttct
     9481 tttcgcagtt tatatcttcc ttttttcaat ttcattgaaa actgtttcga atgtttatgt
     9541 tttacatgga ttttaagcag gagctcctca tgttgcaagc gatagttcct gccttttaaa
     9601 tcagaaaatc tcactagtcc gtattcatca gaagctttca caaatggaac tttttctcta
     9661 gtaatatagt gtttgccgtt gagcgttttt acagaaaaga ccattccttc gattggtcgt
     9721 ccgtttgtgt tctttacata aaaagataaa ggatagtttc gcttagcgat ggccaaagaa
     9781 tctaaataag cgatgagtag ccaaactaag ccgattgatc caagtagtat accgataaac
     9841 caaataaaaa atttccattt tttccattga tcaattcctt ggatcgcttt ttttgcctct
     9901 tttgcttgat aaggaatacg atgccccgtc acaagcagtc gatgtgtatt gaccatataa
     9961 ggagtacagg taagcaaagt cacgagatct ctgccttttt ggatacccaa agaatctact
    10021 tcatcaggta agaccacttg gattttttct acttgatacg ccaatgtctt tccattgatc
    10081 tggatgaaaa actggtctcc ttttttcaac ttaggcaaat ctgtaaataa ttttgcttct
    10141 gggagtccac gatgcccaga aagaacggca tgggtgtttt tcccgccagt cggataagaa
    10201 ctttcttcca ataatgacgt tcctttttgc aaaaatattt ccgttgtctg atcgaatata
    10261 ggtaagctga cattgatttt tgggatttcg atgactccaa gcatatgttc cataaaaaag
    10321 gcattactag gtaaatcttt taatgctttt gcatcaactg cttggttgaa actgcctatc
    10381 cctggtgata cgttttgctc tgccaactgt tggtttttct ttgtcatttt ttcctgctgt
    10441 ttttttattt cctctgaatt cttattcgat gcttgctttt gataatggat gatcatttgc
    10501 tgggcaagaa aatcattcag tgaatcttct acaaaaggat aagaaaagat cccgatccca
    10561 acgactaaaa tgattgccat gaagatgtcc agtattctta ttctgctttt attcatcatg
    10621 tccacctatt ttctaatatg tatatgaaga ggttgtgaaa tcagcgcctt gacctgagta
    10681 ttcgctcaac aaacggcaaa atagttcctc ctattttgcc gtttgttgag cgaataccaa
    10741 gagaccgacc acttgtcaca acctttctcc ccatttgaat cactatcgtt tatttatcgt
    10801 atgatttttg tttccaatag tttaagcttc tgtttcttga tggcgttttt tgaagtagat
    10861 cactgctcct ccaactaaag cagtacctac caagatgaat acgatgatcc ccataccacc
    10921 agttgaaggc aagattcctt taggttggtt atcgatcgtt gtttcatcag aagttgttgg
    10981 atcatcatct actgtaaatt cagtgtacgc agcttcattc ttaggtaatg cgtagccttc
    11041 tggtgctttt gtttcttgaa ggcagtatgc cccttgtttc agcccttcga ttgaaaattt
    11101 cccttctgaa tcagaaatca atttcacttc ttcccagtca gaacctgtga cttcatctga
    11161 ccaagcatat gggtattctc ctgaggcaag atttgctatt tttttcatta atttaacagt
    11221 tggatctttt gctcttagaa tagaaaattc tgcatcggct aatttttctt gcgtgttcac
    11281 atcttgtttg atgaagtgga aatcaccgta gttttggaca ttttctacag taatcgtgtt
    11341 atccgtagtt gtattttccc gattgactac accgtttgga ttcccaagat tggcttcatc
    11401 tgcgccatgg atgataccgg ttgtttgttg caattttccg ttttttacta taaaagtagt
    11461 ttctttttgt ggattggtta attgataacc atctggtgct tttgtttcaa ctaaagtata
    11521 attgccgtct attaatccat tgacactgat ggatccttca gtatcagttg tgaatgtcaa
    11581 cgctgactca gcaggatcat agagagcgac accagtgttt tcatcaaaac cggtcacgaa
    11641 ttgattctct gaatttttga tctggaattg cgcccctgct aacttatcta cccctgaaaa
    11701 gttcccagct ttctggattt tgatattgct ttctttgatg acatttttag catataggtg
    11761 aatcgtgtct aaaggtttgt cagggtctga tgaattcggg ttataaaagg gtaagcttaa
    11821 cacgatattt ggcgacgttt cgacaccggg ctttggtgtt tctacaaaga cgtatacagc
    11881 atctttccca tcagatttac ctggaagagt caggttagct aatccttcac cagaagtcgt
    11941 tacacttgcg aagggtgtag cgtctgctgg aactgctgtg tctttacttg gatagtacgt
    12001 agcagtgatg tcatatacgt tgaattcaac gccgttcaac ggttcgctat tcggaaatgt
    12061 caattccgtt ccgttgttta tttgattttc tggtgctgaa gtgaatttca atttatgcaa
    12121 attaaccgta acattttctg gtgtaggtga tacggcctag aaacctctgc agttcctagg
    12181 ccgagaacga aaggaagcag catgatagca gttcctaaaa acgtccatat ttttgttttg
    12241 atgtttttca ttttatttcc ctcctattgt ttcctttttg ttgtttttta taaaaccaag
    12301 ctgtccctgt tgaaaggact agcaacaacc ctaaaattga gaaacctcca agcatctctt
    12361 cgcttgtttt tggaaagctt cctccatttt tttcatttga tggaccattt gtctgcatct
    12421 gaactggcgt ttttccatta ttcgtcggat ttgcttttgg ttcgttgatg atttccaatg
    12481 gtataggatg aagcggatca taactgcctt tttcaacttc aaagagaatg gttgattgac
    12541 tcaatatata tcctttaggc ggtttaatct ccactagttc gtaacttcca aaagacaatc
    12601 catggacaga aaatgttcca tctttactgg aagtaaaaat cgttgctctt gaatcatctt
    12661 tggctaccca atgatttatc ccgttttctt gcgctaagta ttggtcattt tttttgacta
    12721 gaaattgagc atctgctagt ttttgtttcg tttgccgatc cactttgaca aattgtttgc
    12781 ctcctgtttg gatggcaaga tgtgtttcta ctgtttgatt gtcagtcgtc aaacgtacat
    12841 cgttatcaaa tgtcgttttt tcactgtttt ctttcaatgt catttggtaa cggatcgtta
    12901 attttttccc agcaaacgaa ctaagatctt ttccagaatc tgataagaca aaaccatgtt
    12961 ttgttttttg tgtgtgaaat gtatgaatct tgtctccacc aatcaaaaaa tcgatcgttt
    13021 ctggttctag ccataactga ggatcagctg tatctttgat cgtataggtt cctatctcgt
    13081 tgatgttctc aggaattgtt acggtgatga gataaggaac tttatcccca tctgcaaaat
    13141 ctgtctgctt attctctact gtttttgtta atgtgagtgc agcaggtatt ttttgttcgc
    13201 tctttggata caagtggatg gtcgtcaatt tatgattaga tgaatctgtc acaggaagca
    13261 caacgacaaa tggtgctgat ttttctttta cttaatctga agtctttatt tccgcaaatc
    13321 ggtaaacagc gtcacgacct tgctcatctt tgtccgatgc actaaaagaa gcaatgccct
    13381 cttcctcgtc tactgttttt gtcacatttt ctgccagtat tttttcacta tcactttttt
    13441 gtgctagttt tctttgtgcg tcttccacac tacttccttc tgaccgcagc ttgtaaaatt
    13501 catccgagac atcatatata gcgaaagtaa cgccgttcaa cccttttact ccttgaaagt
    13561 tatccgggat atttattccg tcgttttgac tgatacttgg catcttatcg ctttcgaaca
    13621 ttcgattatg caaagtaaat gtaataggtg attctctagc tgacacagtc ggagaaccta
    13681 taaaaaagac cagtaggata aaaaagagaa cagcaaatat atccacacgt acattttttg
    13741 tttttttcat cgctgttcac ctgctttttt cttacgatgg ataaaataaa agaagccaga
    13801 aaaaataaag atcagtccta aaaagacaaa gggcagtaga cctatcccac ctgtcgaagg
    13861 aagcaagaga gtcggattga tcgtcaactt agcggtatct gttgcgataa tcgtataatt
    13921 attgtttaca cttccttcgc ctaaactaat cgttactatt tgtgatccaa tatctgtccg
    13981 gctgttaact gttagggtat aatccaatga ttcgcctaag acaacaccgg taacgtggag
    14041 atttccaacc gaaatcgagt gactttgggc atcataatta aaggcagcgt catcgacagt
    14101 aatcactgcg ttagctttat agatggtata agttcctgat gtgttggcta tatcagtaaa
    14161 tgacaacttg ggatttgctg ctttgacttt gtctattccg ctattcgtta gtttaattgt
    14221 atagctgcca gcattaacca tattttttgc tgattgtgca tctgctgtgt aatccatact
    14281 gctaagtgcc acttgtactg gagtaagcga actagtgaca ccctctgcta gcttgacatg
    14341 gattgacggg acacctgctt ttccatcata tgtcttactg ccactgagct ctaccgcacc
    14401 gctgatttgc ttaatcgtat agacatcaga tgtctgcacg atagtaaata aatagtttgt
    14461 tctggcagct agtttagcta gtccgctttt tgtcaattgc caagacgtat aggttccaat
    14521 ttcagtaggc gcagttactt caactccctt ttcattcatc gctttgaaat cagttggatt
    14581 ccatgtgatt tgatcaatac tgagatcatt gtttaaaagg gatgttgatt ctgttttatc
    14641 attaaaggca tatttaacga tcggtacaac agaaagacca tcatagtact tactgccatt
    14701 tgcattgatt gatactgttg catttgtctt ataatatagg atgacttcag aaatctgttt
    14761 tccatttgcg tcctttacga ttacatttcc atttgtatct aaactagcta aaacactcat
    14821 tgctgattgg ttctttgttt ctgtcgctga aacagctgta aaggtatatc cgttgatagt
    14881 aggcgtatta gtcgtcaggt cttgtgcagc acttccgtaa gtaagattca ttattttaga
    14941 aggagcaatc atctgtccaa aatagtcttg atacttaata gtgattggtg tttgtttgcc
    15001 tgtataggtc accgtatcga cgttactttc tagggctgtg aaagaaccgt ttgtttgtgc
    15061 aaaagaatag cccgttactg ctgttggagt gataaccact ttgtcaccca catggattcc
    15121 agataatgta gtcccgtacg ttccgatttt tgctgctcca ccattgactg tataagaaaa
    15181 agttcctgtc cgattcgcat tgacctgaac cgttgctgct tgataggttg gaaaatttga
    15241 aacatttccc ttaccatcaa cgatctgccc atttttgatc gagtaccccg tgaatggaat
    15301 atcatttgct aactgtatac cgattgaaaa agtactcata cctcctccgg caggaagccc
    15361 tccccatgtt gagggtgtaa aagaataact tttatccgca ttgggtgtaa ctgaatcgat
    15421 cgtatttcca gcggtagcca cccccatata gatacttttt gggaatgtga tagtagtacc
    15481 atttactgtg gagccaataa acagattatg gatatctgga cggttatcaa taaaagcgat
    15541 tgctttggtt acgccttgta acgcagtttt atccgcactc atcgatccgt taaccgcaac
    15601 aatgactcca tctttggcat atatcactgt atatccatct ggtatggtat gtccgttgaa
    15661 attcgcagtg gccgcaacag tactaaatgt ctggcttcta cctgtttctg aataagcttt
    15721 ctcccctgct gcttttgctg ctgtgatttc tttttctgtc ggatcaatca gttgagtcga
    15781 ggatgtggtt gaggttgtct cgttgttgct agactgattg gtgctttcta tggactgtat
    15841 ttcagaatag ggtggactat ttgtctcctc tgtcgtttgg ttagcaaaat ttgacgtttc
    15901 tgtataaacg tttacataaa tacttgataa gctccctaag aaagtaaaaa tcaagatgat
    15961 cgaaatcata atgggatgta agtattttct tttagataca gctttgagtc tagaaacaaa
    16021 atgtttttga catatacgtt ggattttatt ttgagttttc ttaatcattt tcatccctcc
    16081 tctcaataaa aaatcatcaa ataatccttt a
//
LOCUS       DAZUJR010000067        15981 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.067, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000067 DAZUJR010000000
VERSION     DAZUJR010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15981
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.067"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            226..894
                     /locus_tag="ACG804_002085"
     CDS             226..894
                     /locus_tag="ACG804_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HFS4833006.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(1094..1414)
                     /locus_tag="ACG804_002086"
     CDS             complement(1094..1414)
                     /locus_tag="ACG804_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833007.1"
                     /translation="MGDCFCDGRTSQRYQKNEEEARKQPLPKQQMTLQEIDSILTEAF
                     LSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYFMIDHQPILWEDVRYIELKETKK
                     WFVT"
     gene            complement(1451..2833)
                     /locus_tag="ACG804_002087"
     CDS             complement(1451..2833)
                     /locus_tag="ACG804_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HFS4833008.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            complement(2989..4176)
                     /locus_tag="ACG804_002088"
     CDS             complement(2989..4176)
                     /locus_tag="ACG804_002088"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HFS4833009.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            complement(4183..5214)
                     /locus_tag="ACG804_002089"
     CDS             complement(4183..5214)
                     /locus_tag="ACG804_002089"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFS4833010.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            complement(5260..6684)
                     /locus_tag="ACG804_002090"
     CDS             complement(5260..6684)
                     /locus_tag="ACG804_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015486 -
                     glycoside-pentoside-hexuronide:cation symporter activity
                     [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside-pentoside-hexuronide (GPH):cation
                     symporter"
                     /protein_id="HFS4833011.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMED"
     gene            6859..7764
                     /locus_tag="ACG804_002091"
     CDS             6859..7764
                     /locus_tag="ACG804_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HFS4833012.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            7855..8532
                     /locus_tag="ACG804_002092"
     CDS             7855..8532
                     /locus_tag="ACG804_002092"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFS4833013.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            8529..8699
                     /locus_tag="ACG804_002093"
     CDS             8529..8699
                     /locus_tag="ACG804_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833014.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            8813..9709
                     /locus_tag="ACG804_002094"
     CDS             8813..9709
                     /locus_tag="ACG804_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFS4833015.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(9764..11134)
                     /locus_tag="ACG804_002095"
     CDS             complement(9764..11134)
                     /locus_tag="ACG804_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFS4833016.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            11372..12118
                     /locus_tag="ACG804_002096"
     CDS             11372..12118
                     /locus_tag="ACG804_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFS4833017.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            12115..12954
                     /locus_tag="ACG804_002097"
     CDS             12115..12954
                     /locus_tag="ACG804_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFS4833018.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            12955..13905
                     /locus_tag="ACG804_002098"
     CDS             12955..13905
                     /locus_tag="ACG804_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HFS4833019.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            14046..14798
                     /locus_tag="ACG804_002099"
     CDS             14046..14798
                     /locus_tag="ACG804_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833020.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            14817..15968
                     /gene="queG"
                     /locus_tag="ACG804_002100"
     CDS             14817..15968
                     /gene="queG"
                     /locus_tag="ACG804_002100"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0052693 - epoxyqueuosine reductase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HFS4833021.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
BASE COUNT         5188 a         2995 c         3221 g         4577 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacggt tgtgtaaaaa tatcatttta gagcataaaa
       61 aaaaggagtg gatttctcca ctccaaaaaa gtctaacttt tgggggtcac tacagtgtca
      121 cagtcctttt tttagtaaaa ggatacattt cttccttgta tattccatgc gtgttcgtga
      181 gaaagcatat ataatttaat taacagatag ttagggggag aaaaaatgat tttttcaatt
      241 acaatgaaac tggtgttcgg gttgatcggt ttattattag tggtacgttt gcttgggaag
      301 aaatccatgt cagaaatcac accgtttgat ttagtctata cgcttgtttt aggtgggatc
      361 ttagaagaat caacctatga tgacaatgtc catgtagggc atgtcctatt tgccattgcg
      421 ctttgggcag taatgattta tggtatcgaa cgtatcgtcc aaaaaaatga aaaggtcaat
      481 cgttgggtca aaggcgagcc atctgttcta atcaaagacg gcgtcatcaa catgacagag
      541 ttgacaaata accatatcga gatggagcag ttgcgagcaa tcttaagaca gcaagaatgc
      601 ttttttcttg aaaatgccaa acatgttatc ctagagaatg ccggtcaaat gagtgtattg
      661 aaaaaatcag atgaagacaa agctttatcg atcctgcttg tagatgaagg gcaaattcag
      721 cataaagtgc ttcagtccaa tcaattgact gaagcatggc ttatggagaa cttgaagaaa
      781 gaaggctatg cagatgtaaa acagctgatt tatgttgaat ggtcagaaga aaaagggctc
      841 tacatactaa ataaagaaga cgtcatgcat gaatcttacc gaatagatgg atagatagac
      901 agaggttgtg aaatcagcgc cttggcttgt tactcaaaac taagcgactt tttcacaacc
      961 tctgatatct aatatacgtt gttccagaag ttgcttcttc gaaaaataag ccaaaattcc
     1021 acaaaaattt aagaagcaat tttcgaaaaa tcctttctta ttttttgaag ttgatcactt
     1081 ctgtcacaac ctctcatgtc acaaaccatt tttttgtttc ctttaactca atataccgta
     1141 cgtcttccca caatatcggc tgatggtcaa tcataaagta atcttcatag gcttcaccaa
     1201 tgaagtgccc ttcgacctca tccaagagtc ttccaaattc atcttttaaa ttgagctgaa
     1261 tgattactgc tttacgagat aaaaaggctt ctgtcagtat actatcgatt tcttgcaatg
     1321 tcatttgttg tttaggaaga ggctgtttgc gtgcttcttc ttcatttttt tgataccgtt
     1381 gactagttct tccatcgcaa aagcagtccc ccattttaat ccaaatggcc gatctcgata
     1441 ctcgttatag tcaatgaatt tttttgctgt ccgtctcatc ttttccacct tctaatccac
     1501 tcataccacc tgcatgcccg ccaacgagag aactacgtgc gatggcgcgt cctccttgca
     1561 agagactatg cgcatggatg attgattgaa agccgtattt ttttctaatc gtatcgacaa
     1621 caaaatcaac tttcgcttca tttatctgct tttcaggatc ttcaaaaagg ttaagctgta
     1681 aacctgtcgc gtatacgagg tcggaacagt tcacgcctac acgccgaata tcctggtagt
     1741 ggtaatgctg gtggaaaatg gtcaataaag catctgcaag atctctgcta gcatttgtcg
     1801 cttcgatttt catttgctgg tgaaacccgg tcttgccatt tggatcaaga tagcctaaag
     1861 agtatcctac ccataagctg actacttgtg tttttgctgc agatcgtctc aagcgagtgc
     1921 cgacttggtc ggccatttct ttgataacga tctcgatttc ttctcgtctt gtataatctc
     1981 tatctaggat ttgactattt ccgatacttt ttgattttgg tgtatattct tgtcccaaaa
     2041 aacttcgatc gatgccccaa gcatgggcat aaagctgagt accgatgacc cctagcttgc
     2101 ttttcaagtg ataataatcc gcgtgagcta aatcataaac agaatgtata cccatttgtt
     2161 tcagacgttt tgctgttcgt ttgccgattc cccaaaagtc agtgatatct gagattttcc
     2221 ataacttttc tggtacatct tcataacgcc attcagcaaa catttgcttt ccgtcttttg
     2281 agccattgtc taaggctagt ttagcaagta gcgggttatc gccaattcct atagtcgtgt
     2341 agattccggt ctgctcaaac acatctttat ggatcagttt agccatgtcg tacgcatttg
     2401 ttttaccaaa gagtgccatg ctatttgtta catcaaggaa gctttcatcg acggaataga
     2461 catgatggtt cgcttcgtct gcatattttt tatagataga attgatttct ctgttctttt
     2521 ccatataata ggccatcctt ggggcaacaa tatataaatc acttggatag gggaagggaa
     2581 gatctctggc acggctgata ttggtgatgc cgtaagcttt ttttgctgca ggactggaag
     2641 ccaagattaa tccgctaccc cgtgtttctg tcgaatcgga cggataggac atgactacta
     2701 atttagttgt aaggggatca agatcctttt caacgcactc tacggaggcg taaaaagatt
     2761 tgcagtcaat acataaaata tctcttgaag gttctttttc ataaacaaat accggatttt
     2821 gattcgccca cataacaatc acctcttcaa cacaattaga acacacgttc tctttccgtg
     2881 tcaataaaaa acagcaattt tcaaatacga gcaaaaggct cacatttgga aattgctgag
     2941 aggttatttt tatctatttg tttttagctg agatcgttga tttttttatc aaacatgaac
     3001 agcttctgga tcgatctttg ttgtcccatt tccaatgtgt gcaacataaa attccggagc
     3061 atagccgaca actttcatgt attcatcata gacattgttt ttgaaggcag gtatattttc
     3121 ttctttgaca agagcaatcg cacagccacc aaatccagct cctgtcattc gtgcacctaa
     3181 gacaccttct tgtttttgag cagcatctac tagtgtatct aattcgatcc cagttacttc
     3241 ataatcatag cgaagagagt ggtgagaatc atttaacagt tgaccaaatg cttctaagtt
     3301 cccagcttct aattcagctt ttgccttcaa agtccgctga ttttcagaaa cggcatggcg
     3361 agctctgcgt atcaatgtat catcgccgat ttggtcaata gttgattcaa attcttcttc
     3421 atctaagtct cctaaagaag agataggcaa agttttttgc aaacgtgcca aggcttcttc
     3481 gcattcgcta cggcgttcat tgtattttga atctgccaat tcccgccgct tattcgtatt
     3541 catgatgacg attgcataac catctagttt cactggaacc atttcgtatt tcagcgtatt
     3601 tgtatctaat aagattgcat gatctagctc accgaagccg atggcaaact gatccatgat
     3661 acctgaattg acaccgatga attcattttc tactttttta cctgtttgga ctagttccaa
     3721 gcgatctgtt tttaaatcaa acagatcttc taatacaaca cctactaata attctaatga
     3781 agcgctactg gaaagtcctg caccattagg gattgttcct tccactaata actcaaaccc
     3841 atgatcgatt gagtgtccag cttcttttaa tttaaggacc attcctttta cgtaatttgc
     3901 ccagtttgct tttttatcat attctagctc atctaaagta aaactaatga caccgatatc
     3961 gtcaaagttt gtggaataaa ctaatatttt attatcgtct cgaggtgctg ctacaccttg
     4021 cgttccataa gtgatggaag cggggaagac atggcctcca ttgtaatctg tgtgttcacc
     4081 aatcaaattg atgcgtcctg gtgagaagta ttgtgtagtt tttttaggtc cgaatgtttc
     4141 ggcaaatttt gtgtttaagc ttcttttgat ttccatgatg agttattcct ttcttgtttt
     4201 gattttgaat tctgttactg tttcaaatac tgatccggct tttaaatgaa tcgaaccaaa
     4261 tgctgagaag cgctctgcac ctggagctgt ttgagtctca aatgtgatgc caccgtgatg
     4321 tgccagtttt cggttgcgca tttctggtgt ttctgtgccg aaatttgcag tgaaaataac
     4381 cacactagaa gcatctgtag caatatctac ttggattctt ttatcggggc tagtcaagcg
     4441 agcggcttct ttacccaagc cggtttcttt taagaaaaat ggatgatcga ttccgtcaac
     4501 aagatttttt tgatccaaat cactagcaaa aacggacgct aattttttag gtatttgaaa
     4561 atcgaaagca cttcctgcag cattttcttt tacccctata ggaatactat ctgttcgcaa
     4621 aggagcataa gcttcgctat tgagccaaag ctcatgttga tcgattgact gagaagcatc
     4681 tcccgtcaag ttgaagtaaa catgatttgt cggattgaat aaagtatctt ggtcactggt
     4741 gccgcgagag gtcactcgcc agatattatc ttttgtcaaa gtatagcgga tttccacatc
     4801 cattgtacct ggaaaaccat gttctccgtc gggacttgta gtagtaaaaa tgacagaagc
     4861 ttcattttcg ccattcaaaa tgacataaga ccattttttt aattcaaatc caggagcacc
     4921 accatgcaga ttatgtccag tttttggatc tgtggctaat tggtaagttt ttccattgag
     4981 agaaaagcgg ccattttcga ttctccctgc ggtgcgaccg atagaagcac cgatatacgg
     5041 atctttttcg atatattctt cagcggtgtc aaatcccaaa actaattctc gatcatttga
     5101 ttttaaactg acgattctag cacctaaatc agagatagaa agtgctagct tgtttttgtt
     5161 ctccaaggtt atcaagtgat aaccttggcc aaaatctttt tctgtaatct tcattttcaa
     5221 gatcctttct taatgggaag gaactactgc atcgtgaagt taatcttcca ttgtatcagc
     5281 tggagccaat ttgttttcca atttctcaac gatttgtgca tgttttttct ctgtcaatgt
     5341 aatcttccaa gcaaaaataa tagcggagaa aatcatcaaa gcagcaggag catagaatgc
     5401 ataagctttg aaagtcgtta cgccatgagc agtgatatca gcagcagtag cattaccagt
     5461 catcccagaa gcgatagcga caaaccctac gatcccgtta gacaaagcac cagcgatttt
     5521 atctagtaaa gggcgaattg atagagtaac agcttcgtta cggataccat ttttccattg
     5581 accatattca acagagtctg tgatcgtcat caaagcggat aagaaaatca attgttgagg
     5641 gaagtagaac aatactagcc cgatgataac gattggcaaa cttgaacctg cgatcgtaaa
     5701 gaaaaagtaa gaagaaatca tcattgcgat ccctccaagg taaacgtagc gacgagagat
     5761 gacgcgtgta agcattggga atagtggaac agctactaaa ccaagtaagg cagcaactag
     5821 accaacgatc caaaattcag ttggttggcc aagtacatat ttgaagaagt agaataatac
     5881 ggcagttgtt gctgcattgg caatcgcata agcgatataa gcaagggcaa gccacatcaa
     5941 ctgatcattt tgagcaactg ctttgaacac atctttgatc ccagcttttt cattttgctg
     6001 acggatcgca gtatcgactt cttttgtgcc caaggcagtg ataatcgcag taccgcctga
     6061 aataacagca gcaatcacac cgaaccagaa ccagcctgaa gcgccttcaa tatgtttatg
     6121 agtaacaaga taggtaaaga aagtaacgat agggacaacg actagagtag taccatttgc
     6181 acctagagaa gagccgaaac gagcaaacgt agcaaatttt tcacgttcct ttgtttccgt
     6241 actcaaagct ggaatcattg accaaaaagc gatatcctta aatgaataaa aactatccaa
     6301 taagatgaaa acgattgcaa ataatatgat aaataaagtc gtattatgag tagctaagcc
     6361 aaagaaattg gtaaagattg ctaccaagag tacggaacta acaacgccgc cgataactaa
     6421 ccatggtttg aatttaccgt attttgtacg agtattatcg atgatgccac caatcaaagg
     6481 atcaaaaata atttcaacta agcggatacc tacaactaag cttgtaactg tagcaatcat
     6541 ttttgcattc gttgccttat ctgttcctgc gaacatctgg cttgtcacga ataccataaa
     6601 ataagtgctt aatgtaacat agaatgtgtc gtgtccaaaa gcgcctaaag cgtaggacac
     6661 acgttggatc attttgcttt tcataatctg tattcctctc ctgttcaata tataatacta
     6721 agtaaaccgg ttacaacgaa taacaaagat cttttaatga cttaaactta acaagaaatc
     6781 gcttcctttt taatatattt ctgtgacttt tatttaactt tttgttgcat tatactaaag
     6841 gagtaaggag ggatagacgt ggagcaatcg atttttttaa aaaaggaaca tcaacaagta
     6901 gaaaaagaat tgtattttga tttttgtggt ttctctaaaa cgatgccgtt tcattctttt
     6961 ggtcctgcta ttcgcaatga ttacatcctg catgtcgtga tggaaggcaa aggatcttat
     7021 catgtgaaaa atcaacaatt ccaattgaaa aaaggtgatc tgttcttgat tcgtccagga
     7081 gactcgacgt tttacttatc agatggagaa gatccgtgga tgtattgctg gctttcattt
     7141 ggtgggagtg ctgcagaaga aatcattcgg cagtcgcttt tcagagaaga ccaatacacg
     7201 atggtctctt ctgacataca aaaatatatc gacattattt tagaatgcat gaaagatacg
     7261 gaagaaacct tggaaaatga attacagtta acagcattaa cctaccgttt tttatcagtc
     7321 cttttaaaag atggcggaaa ggtcagcggt ggtgtacaaa aggttcattc ctctttagct
     7381 gttgaaacag tcaaatacat cgaggcacat tatgctgaaa aattgtctgt tgaggaaatc
     7441 gcccagcatt tagcggtcaa tcggagccat ttgtcgcgag tattcaaaaa tcatatgggt
     7501 accagtatca aggaatattt gatcggggta cggatcaatc gaggggcgtt tcttctttct
     7561 ctgacggatg aatccgtgga aagtattgcc tatcaagtag ggttcaatag tctagtcgta
     7621 tttagccgaa tgttcaaaaa gagtaccgga gaaacggcta cgaactatcg taaacgtatg
     7681 aaaaacgaaa attttaagaa tattgctttg gataccttga aaaaacagtt ggaaaaacaa
     7741 accgcagttt cttggacaac ctgattagtc tggttaaaat gacaagcatc ggcaaaagaa
     7801 acttgtggcg gttatgctac actgtaaagc gaagactaaa aaggaggaaa agggatgcgt
     7861 acacttatca tcattagcca tccaacgatc gaagaatctt taaatcagca atttttcaaa
     7921 gaagcttctg ctggtttacc agctacttgg catcatttgg aatcaagtta tccagacgga
     7981 aaaatagata tagagactga actacagctc ttggcccagc atgatcggat cattttccag
     8041 tttccgtttt actggtatag ttctcctgct catttaaaaa tttggcaaga taatgtcttg
     8101 gaacgagcag cacatgtatt aaaagggaaa gaactaggaa tcgtattgac aacaggtgtg
     8161 gcggaaaaag aataccaagc tggaggaaaa gaagaatata cgatttccga atttttgagg
     8221 ccgtatcagc gaatcgcaaa taaattccat atgacctatc ttccgccatt cgttttagca
     8281 caatttatgt atttatccca ggaaaaacgt tgggagaagc taattgctta tcagcagtat
     8341 ctctcattgg aaggcaaacc atcgctgact cagcggattg actggtttat tcaaagagta
     8401 caggaaaatc agaaaatgca ggaagaagaa tctgaaaaac aagcatatat cgtagaagca
     8461 ctgactgagg caaaagagca gatcgaagac ttgaccttta cactgcaaga aatgaaagga
     8521 acttcattat gacaaatgat tggctgatcc aacaattaga tgaattaagc gaaaaatcag
     8581 aatatcaaga ccgtgcgctc ttatatgaaa taaagaaact gatggctgag atagacgaac
     8641 gaacaatgca gctgcaagga gaaatcgacg gacaatcttg gaatcatctc aactggtgaa
     8701 attttcttat aaataacaaa gataaaaatg tgcacagcga caattatttg ctacaataag
     8761 aatatgaagc gtttgataac gctattatac ataaaaattg gtggtgaaaa aaatgtatga
     8821 tgaaaatgag tggggagaaa atgttcggat gacccgaaga agacagcaaa aacaggcagc
     8881 tcgtaagcgg atgatcatga ttggggcagc agttgccgtg tttttgatca tagcaggagg
     8941 agttgcgggt ctatattttc atggaaaaaa ttcgtcagaa gcgaaaagta cgaccataac
     9001 ggaaacaacg acaaagaaaa cagagacgaa acaaacaagt gagtcatcaa ctaaaacaaa
     9061 agagacacaa acttctgaag aaaaaacagc aaatggtttg ccagagcaac ttcaagcaat
     9121 cgtaaatgat tattcgaaaa agatcgaaga aaagacgcct gcattgattg aagaatacca
     9181 gacagaaatt cagggaaatc aagagggaat agctggttta tcagcagttg ctaaccaaaa
     9241 agcacgtgag cttcaagcaa tctccgacga agggatcaga aaattacgtg cagcgtatca
     9301 ggcagcagaa aataaagacg gtgtagactt agatactttg atcaatcaat tatcggctaa
     9361 ttatacgaat catgtcgcta agatttccga tatttatttg cagactagcg cctctcttca
     9421 agcagagtca acaagcacac aagacacaac atcttctgat tctgagacag cagagtcggt
     9481 agaagcttct gaaatgcaag ctcgaacaac acaagacaca acagattcct ctgaaactaa
     9541 taccaacagc gcgacttcac aggctgcgac aaccgtagtt ttggaaggag aaggtccaaa
     9601 tcaaatagcc gaacgaactg gcgtaccagt agaaacgatc ttgtcgctga atgggatgag
     9661 catggagaat tatttcctga ctcccggtga gacgctaaaa ttgaattgat aaaagcaata
     9721 aaaaagaacg aagcttccac taaggtgaag cttcgttctt tttttatttt ccggttcttt
     9781 tttcgcgtac aaagtaatgg atcgtcatgt aaagcaagaa aacgagtcca ataatcaatg
     9841 agattctcgt ttcaggattg ataaacatga aaatcaatac gatagctaaa aaagcaagtg
     9901 tcacataatt cgtataagga gatagtggca ttttaaaagg atgatcatgc attttatctg
     9961 cgtgcttctt tttgaagcga atctcgctga tcaaaatcac tacccaagga accataccag
    10021 gcaaaatact tgagctgtat acgaaaacga aaatattttc tgactggttg atgaacattg
    10081 gtagaagata atttaagatc agaccaatta agattccacc tgagattgct acgacaggat
    10141 aaaaaggcgc accgtgacga gatagtttca gaaatttttt agacatcttt ccatttatgg
    10201 caagtgtata gaccatacga cttgcgctga aaatccctga attgcaacct gataatgccg
    10261 ctgtaatcac gacaaaatta atcagtcctg cagcaaatgt aatgccgact ttagaaaaag
    10321 tttgtacaaa aggtgaacca atctcactca attgattcca cggatagata ctcacaatga
    10381 taaaaatagc accaatataa aaaatcaaga ttcgaccgat agtggactgg acagcttcaa
    10441 tgatcgtctt tttaggattc tctgcttcac cagcagtcat tccgatcagt tcgattcctt
    10501 gataggaagc aacaacgatc gataatgcaa agaaaaatcc tttgacgcct ccagtgaaga
    10561 atccaccatt tttccaaaga tttgaaatcc ctactgcctg accatgatta ccaaatccaa
    10621 ataagattac cccaagacct gcaatgatca tcaaaatgat cgttatgact ttgatgatcg
    10681 aaaaccaaaa ttctaattcg ccaaacgcct tgacagaaat aagatttgcc agcataagaa
    10741 acaagacgac aatgattccg ggaataattg ccggcaaatc aggccaccaa taattcatat
    10801 aagatcctac agcaatcact tcacttattc ctacgacaat atattgaaaa atattactcc
    10861 aagcggtcaa gtagccagcc acaggatgga tgtactcgct cgcgtaattt gcaaaagaac
    10921 cagtcgaagg atcaacgtaa agcatttcgc ctaaagcacg cataatcaaa tacaaaaaga
    10981 atcctgcaat cgcataggct cccatcactg agggccctgt ccaacgtatg gttgaggagg
    11041 cacccataaa cagaccgaca ccgatcgttc cacctagtgc gatcatttgg atatgacggg
    11101 cactaagact tcgagttaac ttttcttctt ccatacaaaa actcctttcg ttgttgagtc
    11161 aacaagaaaa aataatcaaa cgtttcaaca catgtttttc attattaggt tagccttatt
    11221 gaactcttga tgtgattcta cagaaaattt tcataaaatg cgaggaaaat tcgaaaaaaa
    11281 ctttttcatc attctacttg aaaatgcttt ccattttagt taaactatat ttaaataaaa
    11341 agttaggtaa acctaaaaag gagtgtaaga tttggaacgt acggccattg taattcaaga
    11401 cctttcagcc gcttatcaag ggaaaactgt tttgaaaact atcaacttga cgataaatcc
    11461 acaaaaaatt accggtatta tcggaccaaa cggtgcagga aaatcaacat ttatgaaatc
    11521 tttgctagag ttgataccag ctactactgg taaagtcacc ttttctggac agtcggtaaa
    11581 ctcagtccgt aaaaaaatag cctacgtgga acagcgaagt gaattggatc tttcctttcc
    11641 aattgatgta ttaggcgttg tacttttagg aacatatcca tctttacgaa ttggacaaag
    11701 acctgggaaa aaagaaaaag aacgtgcaag acaagctttg aaaaaagtag ggatggaaga
    11761 atatgccaaa agacagatca gcgaactatc gggtggacag cttcagagag tttttattgc
    11821 aagagctcta gcccaaggag cagaatggat ctttttagat gaaccattcg tagggattga
    11881 tgcgttaagt gaacgaaaga tctttgacat cttgcaggaa ttgaagaatt caggaaaaac
    11941 gattttgatc gtccatcatg atcttcataa agtagaagaa tatttcgatg aggttattct
    12001 tttaaataaa cagctgatcg cttccggtcc agtacaagaa gtctttacat cgaagaacct
    12061 tcaattggcc tatggtgaga tcatcagaca tttagtaaaa ggaggagaga aaaaatgatc
    12121 caatccttta ttgatggatt aatgaattat caattcctgc aatacgcttt ggtcacttcc
    12181 atgcttgtag gacttgcttc tggagtcatc ggttctttta ttattttacg agggatgtct
    12241 ttgatgggag acgctatctc tcacgcagtt cttccaggtg tagccatttc ttatatgttt
    12301 ggttttagtt acatctttgg agccactgct tttgggatgc taacagcagc agtgattggt
    12361 ttcgtgactc agcggagccg attgaaaaat gatacagcga ttggaattgt ctttagctcc
    12421 ttttttgcat tagggattat cttgatttca tatgcccaga gtgcgacaga tttgtatcat
    12481 attttatttg ggaatgtctt agctgttagg gaaagcgatt tgttgctgac agcactcgtt
    12541 agtggaatcg tcttgatatt tgtctttttc ttttataaag aattgaagat cacatcattc
    12601 gatccgacaa tggcaaaagc ttatgggctg aacacatcgc tgatccatta tcttttgatg
    12661 ttctttttga cattagtggc tgtagtcagt ttacagacag taggaacaat cttggtgatt
    12721 gccatgttga tcacaccagc cgccacggct tacttgctaa cgaaccattt actgaaaatg
    12781 atcattacag ctgcaggaat cggtatgcta agtgcagttg tcggtgtgtt tttcagttat
    12841 agttacaatt ggccatcagg agctacgatc gtgttagcat gtaccgcatt ttttatcctt
    12901 gcttttttat tttctccaac aaaaggaatt ttatttcaga aaggaagcag atagatgaaa
    12961 acaaaaaaat cactcttttt aatcttggca gttagtttct tggtattagc cggttgcgga
    13021 aagcaggctt ctgaccaagc ggatgaagga agtaaagaaa agttgtcagt cgtggctacc
    13081 aattcgatct tggcggacat ggcaaaagag gtcggaacag atcaaataga tatccacagt
    13141 atcgtaccag tcggaacaga tccgcatgaa tatgaagtac taccagaaga catcaaaaag
    13201 gcaagcgatg cagatgttat tttatacaac ggtttgaatc ttgaaacagg taacagctgg
    13261 ttcgataact tgatggaaac ggctaaaaaa gaagaaggaa aagattattt tgcagttagc
    13321 aaaaatgtag aacctcttta tttaactagc ggtgaagaac atacaaaagc agatccccat
    13381 gcttggctag acctatctaa cggaataaaa tatgtggagg aaatcgcacg tatattctct
    13441 gaaaaagatg cagaaaatgc gacactctat aaaaaaaatg cagaagcata tgtggaaaaa
    13501 ctaaaagaat tagatacaca agcgaaggaa agttttgctt ctatcgaaga gaacaaaaaa
    13561 ttattagtaa caagtgaagg ggcattcaag tatttttcac gagcatatga tttgccagca
    13621 gcttatatat gggagatcaa tacagaaagt caaggtacgc ctgatcaaat gaaagcgatc
    13681 attgatcaga taagagcaaa agaagtaccg gttttattcg tggaaaccag tgtagactca
    13741 agaagcatgg aacgggtagc aaaagaaacg ggtttgaaaa tctatgataa actgttcact
    13801 gattccatag caaaagaagg agaacaagga gattcttact atcagatgat gaaatggaat
    13861 attgaaacga tccatgaagg tttgtcacaa acaaaagaaa gctgaaaagt gcaaggtcta
    13921 gcttgaggag cagaccttgc attttttata agagatatga aaaaaaatta tgctgttttt
    13981 cgtcgtacag ataccttttt tgaagaaatt ccgttatagt tagagtaagg aaggaaggtg
    14041 tggctatgaa ttttacacgt aaagataaat atacgattaa agaagaagtc tttcgattga
    14101 tcagccagca ggaaaatacc gacaaggatc aagaccttca atttcttgaa gcagaattag
    14161 ctaaattatt catagcaaat caaaatgaga caacagaacc agatgaagag ctgtacatag
    14221 gcaaatggtt gtttgatgaa tttcagcctt tagatgaaaa taccggtatc ggttattttg
    14281 tgttcctttc tccagtcggc ttcacacctg gcgtattagt taaacaaaac gacgaaataa
    14341 ccgtcaaagc atggcctgca ttattttcag tcatcaaagc agaaggagta atcaaaaaga
    14401 tccagtcggc ctattataaa agtcaattta ttgccaacag caaattaatg aatatgtttt
    14461 ataatcgtct agtagaaatt gctaggcctg ggaaaatccc gcaaacattc acgtacacac
    14521 agcaaaaaaa tctctatgaa gaagtattgt attcccgcga tctgtctgag ttttcgccat
    14581 gggaagaggt aaggctccat gaactgttaa gtacaaaacc agtttcattg aattttttta
    14641 atgcattaga taacaaaaga aaattaattt caacaaatta ttgggaagta tttgctgcaa
    14701 gaaaaaaatg gatggaagaa aagaagattg ccgatcagca gatccagttt gtccagctga
    14761 aaaaagaaaa actatattat gggttataca gccgttaaca gcaagcgagg aagaccatga
    14821 cattaaaaga agaaatcata caagaaagca aacgattagg aattgacaaa atcgggttca
    14881 ccacggcgga accttttgat tcattaaaag aatcgttgga agaacaaaaa gcagctggcc
    14941 atacttctgg ctttgaacat ccaaatatcg atgagcgtct ttatccagaa atgacatttg
    15001 atcagccgaa atcgatcatt tccattgcac ttgcgtatcc tactaggatc catgaagaag
    15061 tgcctaggga tgaaaaacgc gggcagtttg ctcgtgcttc ttgggggatc gattaccatg
    15121 atatactcag agaccgtttg aaccgattga tcgaattcat ccaaacaaga gcagaaaaat
    15181 ggcaaaaaga agaggaatgg cgtctagctc cgcaagtaga tactggagaa ctgatcgatg
    15241 tcgctgtagc acagcgagct ggtttaggat ttattggacg aaacggattg ttgatcactg
    15301 aagagttcgg ttcatttgtc tatcttggtg agatcgttac taatattgta tttgagcctg
    15361 ataaaccagg agaatttggt tgcggtgact gtatgcgctg cgtgactgct tgtccgacaa
    15421 aagcattgct tggtgacgga agaatgaatg cccagcgatg tttgtcttat caaactcaga
    15481 caaaagggat gatgccggaa gaatatcgta aaaaaatgcg aaatgtcatt tatggatgtg
    15541 atatctgcca gttagtctgc ccttacaatc aaggaaaaga ttttcatttt catgaagaga
    15601 tggaaccaaa agtagacgaa atatatccaa aattaaagcc aatgctttcg atgtctaata
    15661 aagacttcaa acagcaattt gggcatttag ctggttcatg gcgtgggaag aaacctttgc
    15721 agagaaacgc attgattgct ttagctaatc taggtgatcg aacggcattg cctgagattt
    15781 cagaatgttt aacagatgtc cgccctgtca tcagaggaac agcagcttgg gctattggac
    15841 gtctaggaac aaaagaaccg gaaaaatggc ttgatgtatt agatgaaata ttagctaaag
    15901 aaacagaaga agtcgttata aacgaattgg aacatgccca gaaattattg cggagaaagt
    15961 taaaataaaa aaatagttaa c
//
LOCUS       DAZUJR010000068        15256 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.068, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000068 DAZUJR010000000
VERSION     DAZUJR010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15256
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.068"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(501..1067)
                     /locus_tag="ACG804_002101"
     CDS             complement(501..1067)
                     /locus_tag="ACG804_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFS4833022.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1067..2023)
                     /locus_tag="ACG804_002102"
     CDS             complement(1067..2023)
                     /locus_tag="ACG804_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HFS4833023.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2023..2679)
                     /locus_tag="ACG804_002103"
     CDS             complement(2023..2679)
                     /locus_tag="ACG804_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HFS4833024.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3049..5067
                     /locus_tag="ACG804_002104"
     CDS             3049..5067
                     /locus_tag="ACG804_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFS4833025.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    5137..5343
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5494..7908
                     /gene="leuS"
                     /locus_tag="ACG804_002105"
     CDS             5494..7908
                     /gene="leuS"
                     /locus_tag="ACG804_002105"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HFS4833026.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8256..9809
                     /locus_tag="ACG804_002106"
     CDS             8256..9809
                     /locus_tag="ACG804_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WD40/YVTN/BNR-like repeat-containing protein"
                     /protein_id="HFS4833027.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10190..11974)
                     /locus_tag="ACG804_002107"
     CDS             complement(10190..11974)
                     /locus_tag="ACG804_002107"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4833028.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(11989..13710)
                     /locus_tag="ACG804_002108"
     CDS             complement(11989..13710)
                     /locus_tag="ACG804_002108"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4833029.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            13810..14571
                     /locus_tag="ACG804_002109"
     CDS             13810..14571
                     /locus_tag="ACG804_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFS4833030.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
BASE COUNT         4975 a         2776 c         3001 g         4504 t
ORIGIN      
        1 ctgctttgat cataaaagtc tgcatattca tcactgatat tttttctaat aaattcttcc
       61 atcataaaaa tcacctcaaa acgattatac gaacttacgt tcttgttgta aagcgatatt
      121 tgaggggcaa aaaaggggca taatttgact gatattaagt tagctattga tatatgaatg
      181 acatacaaaa atataaaatc ttttaaaaat gcttatatat caatgttttt gccattcttt
      241 tatatatctg ttatatgtca aaaaaatgtg ttcaatttca atttgtattt gaataaagag
      301 gttgtgaaaa agctgtcctg catcaagtaa taagaacagc caatcaaaaa cagcttctca
      361 tgtttttgat ttggttggac ttattaccgc agatataagc ttttgagcac cgtgaataaa
      421 gaggttatga aatcaacgct ctaacctgag tattagagaa aaaaacgcaa aacatatcat
      481 ttatgttttg cgttttttat ttatcttttt ttctcaatac aatataaaat aggcggctgg
      541 ttcttttggt tgataaaccg ataattcagc acattatatg tttcctgtgg cagtttggaa
      601 caaaaagaat caaccatatc cagttctttt tctccacctt catgaccata gtagacgaca
      661 aggatcaatc gtccgcgagg cacaagtcgt ttcaatattt cttccatagc tgtgcgtgta
      721 gtctctggca tagtgatgat tgctttatca ctttttggga gataccctag attgaaaatc
      781 cctgctttga gattttgttg ttcagctatc acttctccta acgtttcgtg gccttgtaga
      841 aacaatgaga cacgttcttc taactgacgc tgttctagcc tttcacgagt agcatcgatt
      901 gcttgttgct ggatatcaaa actatagaca tgaccagttt ttccgatgtg ttctgctaga
      961 aaaaccgtat cgtggccatt gcccatcgtt gcatctacga cgtgatcccc tggttgcaag
     1021 atttcttgca gtaatgtatg gctgaaatgc aaagcagttt gcaacatcag acgctcacct
     1081 ttttccgtac atcatatttt ccttggaagc tatctctgcg aagaagttct tcatcaattg
     1141 cattcaagac ttcccatttt ttcaagctcc acattggtcc aatcaaggaa tcccacggcg
     1201 catcccctgt caaacgatgg atgatgatct cttttggtat catttccagc tggtcgcaaa
     1261 tgacattgac atagtcagga cggctcatta attgaaggcg accttcatga tagtcccgca
     1321 acattctcgt tttgcgcatc agatgcatca aatggagctt gattccttgg atatctgaat
     1381 ctaaaatggt gcgtctgaca ttttctttca tcatttctaa actttcgcct ggtaatccgt
     1441 tgatcaaatg cgtacaaaca cggatattat gtttgcgtaa tttagccacg ccatctaaat
     1501 aagtttgata atcatgtgct cggttgatca gttttgaagt ttcttcaaaa gttgtttgca
     1561 atccaagttc tacccataaa tacatccgct cgttcagttc agcaaggtaa tcaactactt
     1621 catctggcag acaatccggt cgtgtaccga ctgataatcc tacgacacct ggtaaattga
     1681 ctacttgctc aaatcgttct ttgattattt caactggcgc atgggtgttt gtaaaatttt
     1741 ggaaataaac gatgtattgt tggacatgag gccatttttg atgcatcatg tcgatttctt
     1801 tctggaattg gattggaaga gggtcttcag gtgcaacgat catgtctccc gaaccagata
     1861 cactgcaaaa agtacaaccg ccatgggcaa cagtcccatc tcgattcgga cagtcaaatc
     1921 ctccatcgat cggcaccttg aaaattttcc cgccaaactc atttcgtaaa gcgtaattcc
     1981 aagaatgata tcttttattt ccttctgaat aaggaaaagt cattaaaagt ccttctttct
     2041 gtaagagtta tctatttgtt ttcttttttc tctatacact ggataagtca ggcacagcca
     2101 agaaagactg agtaagtagc cgccgatgat atcagtagga aaatgaacgc ccagataaat
     2161 gcggcttatc ccgacactta ctataataaa catcatcagc aattgaagca atgtgcgtaa
     2221 ggttcttttt tgaacaaaag ctggaagcag aaatagtaaa gaaccgtaaa gaatcatact
     2281 gcctgctgca tgtccactag ggaaactgta acttgtttca actactaagt gcgccaatga
     2341 aggacgctct cgcatgaaaa atagtttgat caccgggttg atgattccag caattacaat
     2401 aaatccagaa acgaaccaaa atgtttctgc cctttttttc ttataccaca tccataaagc
     2461 cgcacaagca aataaaatga tgacggtaag aggattaccg aatttagtca taaagagttg
     2521 gtagctgttc agatcaggat aagaagctct gacaatgcct gtaaaccact gatcgaaacc
     2581 agaaagccac gacagatgga actttacgat ccagcccaaa atgaaaaaca ggacaagaaa
     2641 gaagctacca gccacctgaa atgatgtttt atatttcata caattcctcc tttgaagcaa
     2701 tgacttatta tagcattttt ggtccagcga aaaaaacggt aaagagataa aaccaatgta
     2761 tgattcctct ttgaataacc aatattctta taaaaaaaat aactgtaatc ggaaagacat
     2821 tttttggtaa tgcaaatgaa atgttaggga aataaaatca gtgtttttcg aaatcctttt
     2881 aaacaagaac gtagacgtag gaagaacttg aaaatgaaca gaagttgttc attacggtaa
     2941 attacaatat gattacaaaa aacaacaaag ctcttaaata acttttaata aatattaaga
     3001 gaagttataa ttattaataa tagataaatt gaagttggag gatagaagat ggaaaacatt
     3061 gcaagaaaag aacggagacg tttagaacag accaaacgtt ttcgaaaagc aaaacgaggg
     3121 gcagcaatcg tgggaactgc gatggtaggc tgttctgtcg ctgccccatt agtacagccg
     3181 gttcctgttc aagcggatga aacacctgtt cagttcggcg caagaatcaa tacagcggca
     3241 tttatcacag aaattgctac ttatgctcaa ccaatcgctc aagccaacga tctatatgca
     3301 tcagtgatga tcgcacaagc agttgtagaa agcggttggg gcagtagtgc gttatctcaa
     3361 gcaccttatt ataatctttt tgggataaaa ggcagctatc aaggacaaac cgtctacatg
     3421 gatacgcttg aatttttaaa taatcaatgg gtaaataaaa aggagccttt ccgacaatat
     3481 ccttcttttg ctgaatcttt caatgacaat gcctatgtac ttagaaatac ttcatttggc
     3541 aacggttatt actatgccgg tacttggaag agcaacacga aatcctatac agatgcgaca
     3601 gcttgtttga cagggcgtta tgcgactgat cctggttacg caggcaaatt aaataatatc
     3661 atcgcaactt acggattgac ccaatatgat acaccagcta gcggaaacgc aggcggtgga
     3721 gcgactacag gtggcaataa tactggaagt gcaggtagta ctggcggttc aagcaattct
     3781 ggtaatacaa actcaggttc agcaacttcg accacttata ctgtccaatc tggtgattct
     3841 gtttggggaa tctcaaataa attcggtatc acaatggatc aattgatcca atggaacaac
     3901 atccaaaaca atttcattta tccaggacaa aaactgacaa tcaaaggtag ccaggaaaat
     3961 ggctcttcga cgaataattc cggtaacaat accaactctt caggaaatgc tggtacatca
     4021 aacggaggac aaacaactgg tgcgaaatac actgttcaat ctggtgattc tgtttggaag
     4081 atctcaaatg atcacggaat tacgatggct caattgattg aatggaacaa tatcaagaac
     4141 aatttcgttt atccaggaca acagctaatc gtatcaaatg gcggttcttc taatgctgga
     4201 gcaaatactg gctcaaatac tgggaataca agtggctcta gttcgtccag ctcaagttct
     4261 tctaatacag cttcaggaac gaaatataca gttaaagccg gagactctgt ttggagcgtc
     4321 tcaaataaat acggaattac gatggctcag ctaatccaat ggaacaatat ccaaaataac
     4381 tttatctacc caggacaaca actgactgtt tcaaacagtg gatcaacaaa cagcacgtca
     4441 ggtaatacag gttcgtcaac caatacaaat aacagcagtt cagttaatac tggcagcagt
     4501 tcgtctcaag gcacttatac cgtgaaagca ggtgaatctg tttggagcgt ggcaaataaa
     4561 aacggcatca cgatggatca gttaatcgaa tggaataata tcaaaaacaa cttcatttat
     4621 ccaggacagc aattgatcgt taaaggtgga acttcggcaa atacaaatac aggttcaact
     4681 acttctgcag cgaaaccaaa tacaccgaat acgtctgcta cgacaagtac atcatccact
     4741 ggtaatacga tgtataccgt gaaagcgggc gagtcagttt ggagcgtagc gaacaaacat
     4801 catatcacga tggatcagtt aatcgaatgg aataatatca aaaataattt catctatcca
     4861 ggacagcaag tgattgtgaa gaaaggttca tctcaatcaa caaaccaaca atcagttact
     4921 ggttcgaaaa cctatactgt gaaatctgga gaatctgttt ggagtgttgc tgacagtcat
     4981 ggaattacaa tggctcaact aatcgaatgg aacaatatta agaacaactt tatttatcca
     5041 ggtcaaacgt tgattgtagc taaataaaat agctgttcga agaaataacg attgaattcc
     5101 acaaaaatat ttgttactat aaggctactt aaatatgaca acacttgaaa aggaagtagt
     5161 aaaaagactg aagtttcaga gagcgcatgg ctggtgagaa tgtgcacgga tgcttttgaa
     5221 ctcgcctttg agttgccctt gctgaatacc cgagtaagca agcggcggtg acggccgtta
     5281 caacgttcga ggccttttca ctaaggtaaa attaggtggt accgcgtaga ttacgtccta
     5341 taaaaagagc aatcttttta taggattttt ttatttcttt tgtgaagttt gagaaaacaa
     5401 agcaaaagga aataaaaata aacagattct gccggttttt tcgttatatt tataatagaa
     5461 acaagtgttt tcaatagaac aggaggacag caaatgagtt acaatcataa agaaattgag
     5521 aaaaaatggc aaaaatactg ggcaaaaacg aatactttca acacccatga tgatcctgaa
     5581 aagccaaaat tttacgcact ggatatgttt ccctatccat ccggtcaagg gctacatgta
     5641 gggcatcctg aaggttatac ggcaacggat atcctttcac gtgtgaaaag aagtcaagga
     5701 tacaacgtgc tgcatccaat ggggtgggat gcattcggtc tgcctgctga acaatatgcg
     5761 ctagatacag gaaacgatcc agctgagttt acccaaaaaa atatcgaaac attccgacgc
     5821 caaatcaatt ctttaggatt tagttatgac tggaatcgcg aagtgaatac aactgatccg
     5881 gagtattata aatggacaca atggatcttt acgaagcttt atgaaaaagg tctagcttat
     5941 gaagcagaag tagcggtaaa ctgggtacct gaattaggaa cagttatttc aaatgaagaa
     6001 gtgatcgatg ggaaaagtga acgtggtggc tatgatgtag tcagaaaacc aatgcgccaa
     6061 tggatgctga aaatcactgc ttatgctgat cgcttattgg atgatctaga attagttgat
     6121 tggccagaaa gcattaaaga aatgcaaaga aattggatcg gtcgttcagt aggagcaaat
     6181 attgaattta aagtggctgg tacggataaa tcctataccg tatttacgac acgaccagat
     6241 actctattcg gtgcaactta ctcggttctt gcacctgaac tagatcttgt tagagaaatt
     6301 acgacccctg aacaaaaagc tgctgtagaa gcttatatcg aagagacagc taaaaaatca
     6361 gatctaaaga gaacggatct tgcaaaagaa aaaacaggag tatttactgg tgcttatgca
     6421 atcaatccag ttaatggcaa ggaaatccca atctggatcg ccgattatgt attatcttca
     6481 tacggcacag gagccatcat ggctgttcca gcacatgatg aacgtgactt tgaattcgct
     6541 caaactttcg gactagaaat tcttccagtt atcgaaggtg gagatgttga aaaagctgct
     6601 tacacagaag atggtacgca catcaactct gaatttctag acggcatgaa caaacaagaa
     6661 gcaatcgata aaatgaatga atggctagaa gaaaatggcg tagggaaaaa agaagtcagc
     6721 tatcgcttac gtgactggct attctcccgt caacgttact ggggtgaacc aatcccaatc
     6781 atccattggg aggacggaac agtcacagct gtcccagaag aagagctacc attacggttg
     6841 cctaagacaa aaaacatcaa gccaagcggt actggagaat ctccattagc aaatatcgag
     6901 gagtgggtca atgtcgttga tcctgtaaca ggtaaaaaag gccgtcgcga aacgaataca
     6961 atgccacaat gggcaggaag ctcatggtat tacctgcgtt atatcgaccc tcataacaaa
     7021 aaagaactag cagattatga aaagttgaag cgttggctac cagttgacat ctacattggt
     7081 ggagcagaac atgcggtact tcatttacta tatgcacgat tctggcataa attcttatac
     7141 gatatcggtg ttgttcctac aaaagaacca ttccaaaaac tatacaatca aggaatgatc
     7201 ttaggcgaaa acaacgaaaa aatgtcaaaa tctcgtggta atgtagtcaa tcctgatgat
     7261 gtggtcgaaa cttacggtgc agatacactg cgcatgtacg aaatgttcat ggggccatta
     7321 gatgcttcga ttgcttggag cgaaaatggc ttagaaggaa gccgtaaatt cttggatcgt
     7381 gtatggcgtt tgatcgttga tgagaacaat aaaatgcgtg accgtatcac tacattgaat
     7441 gatggcaagc ttgataaagt gtatcatcaa acagtgaaaa aagtgacaga agactatgaa
     7501 aatcttcatt tcaatacagc aatctcccaa ttgatggtct ttatcaatga agcctataaa
     7561 gtggacgctc tgccttatga atatatcgaa ggatttgttc aactactcgc accgattgct
     7621 cctcacatgg gtgaagaact atgggcaatc cttggaaatg atggtggtat ttcttacgca
     7681 ccatggccaa catacgatga agcagcactt gttgaagacg aagtagaagt tgttttccaa
     7741 gtaaacggta aagttcgtgc gaaaagcaat gttccccgag acttaggaaa agatgagcta
     7801 gaaaaagcag cattagccaa tgaaatagtg caagaatata ttgaaggcaa aacagtcaga
     7861 aaagttattg cggtaccaaa caagttagtc aatatcgttg ctaattaatt ggctctttgt
     7921 caataaggac tgatgagttg tgcaaaatca aatctgggcc agaatgaact tcattctgtc
     7981 tcagattttt tgttatttca aattgattaa ttgattgatc aaaaaggttt tgattttcat
     8041 gttctcaaac acgttcaatg tctttttctt ctgaatggtc ttgtaagaga tctctgtaat
     8101 catcaaattt ttgtctatta atcttagtat tttttgatgt ataaactacc tgaaattgag
     8161 agtacatacc aaattcataa attttttatt agtgggacta gtgattgtat ggattttgac
     8221 gcataatgaa tgaagtatga gaaaaggaga gacaaatgga tcaagaacta tttattatcg
     8281 aagtattatc agctaaacaa aaaattatcg agaaagcgaa aaaaagagcg aaaagaataa
     8341 tgttcaagct tttaagctta gtatttttct ctggtttgct ttttttcgga gctgtatcgt
     8401 tcctatatcg ccatatgagt gcagtagtcc gttcagctga agggatgcaa aaattaaata
     8461 atttgtatca cttttcgtgg ggagttggcg gaataacaat tgttgtgctt attgtttttc
     8521 ttctacttat ttggctccgt taccatcaat tgtcgcgtca tttcgatcaa tggcttagtc
     8581 aaagagcaca acagttttta cataataaac caacttctca agatgatgac tatctttatt
     8641 ttgagaagac ttcgacgagt caagcttttc ggatacaaaa aagtgattgc cagttattgc
     8701 tgagatcact tgatgattta cctatctact taggcgaaag caaatcaaaa ttcggaatga
     8761 acacattcca tattttttta ctagaaaacg aacccagatg ggaaaaaagc cagtcttcgc
     8821 ctggtggata cctgacaact aagatgagta cattagtcac tggttttttc ctcattcttt
     8881 tagctggaac aatctattat gggagataca ctcagccaaa aatgtcttct catataaatg
     8941 ctgcttctca catgacaatg aactcaacta acgatacgca tatacaaaag acaaatgaag
     9001 ggttgttagc tgatcctaag caaaaggtaa atttgacaac acaaaagata aatgatctca
     9061 aacttgatac agagacgcac tctctctata tgacaacaga tagtggtgct aattgggtat
     9121 ttgtgccgat tgattcgcaa tggttgcgtt ttggcgaata caccctgaca acggggctga
     9181 ttcctgaagg ttattggatg gacaacacat atgatatttc cgccgatttc tcatggttta
     9241 tctattcttc tggggatgat gtacgtctgc tgacttcaag agataatggt aaaacatggc
     9301 aaacgtctat tatcacccaa tcagttcagc cgatacgtta tcgaaaagcg gtattttatg
     9361 gcaacgatgg tctatttatc tgtacatcag ccagtgggat gtctgcagaa actttgtaca
     9421 tttacactac tatggatggc ggaatcactt ggataaaaag tggaagtaca atgatcaatc
     9481 agccagtaca aaatgtcagc ttcgttacaa cttctttagg ttttgtttcg acacgtgaaa
     9541 gtttgtttta tacaaacaac ggaggacgct cattcaaaga atcagttctg tcgattccgg
     9601 aaaactatca gacagggggg atagatcttt ttcaatcacc aaatgaagtt actcaaataa
     9661 gcgcgaatac gttagagaca aaattttatt tgttgaaaaa aggaccaatc gatgcaggga
     9721 aaatgtttgc ctgcctcttc cgttcaactg ataacgggga aacatggcaa ttcgttcagc
     9781 aactatcgca agtagaacaa ggagattaaa gaagagagat tgtgagcctg acgttcagca
     9841 ccgagtcaca agaaacaaat tcaaaaaaca gcttctcata tttgttgaat agtgtaactc
     9901 gtgattcgga gttgacaaga gcaacaagaa gcgattttga agtatagctt ctcgtatttt
     9961 acaagatcgt gtcttattgc cgataggttg tctcttgaac accgtttatt cgtaaaaagg
    10021 gattgtgaca agtcttttgt cactacttac cgaacgaaac tgaaggagct atccaaaaag
    10081 tatcattagt attattcttt gtgtttctag tggcaccact agtacattta aaaaagctat
    10141 cgatcatgga ctaatcatac atgatcgata gctttttaga taatgtttgt tacgctatct
    10201 gaaattgact attataaaga ctggcataaa gcgttggtga ttggagtagt tcagaatgtg
    10261 ttcctttttc gacgatatcg ccattcttca ttacaaggat catgtctgca ttttcaatcg
    10321 ttgacaaacg gtgtgcaatc acaaaacttg tcctatcttt tgtcacagct tccattgctt
    10381 gctgaatcaa tgcttctgtt cgtgtatcta cgctagaagt tgcttcatct aaaataacga
    10441 caggaggatt cgctagaatg actcgagcaa ttgtcaataa ttgttgctgt ccttgagata
    10501 acgtgccgtt ttcgctagaa atgatcgtat catatccgtc tggcagtgtt cgaataaagt
    10561 gatcacattg tgcgatttca gccgcttcga taatttgttc tcttgtggca tccattttcc
    10621 cgtaggcgat attatcagct accgttcctt caaacagcca ggtattttgt aaaaccatcc
    10681 caaaagaacg acgtagttct ccacgtgaaa gcttggtaat atcaagaccg tcgaattcga
    10741 tctttccttt attcagttca taaaaacgca tcagcagatt gactaaagtc gtttttcctg
    10801 caccagttgg accaacgatc gctaccgttt gttttggctt tactgaaaaa tcgacttgat
    10861 tcatcaatat tttatctgat gtgtaaccaa actgtacatt tttgaaagct atttttcctt
    10921 tcggttgttc taaaagtctt gcatctggaa ggtctggaat ttcatctgtt tcatctaata
    10981 tctcaaatat cctatcgatt gctgccattg cggattggat cgagttgatc acataagaag
    11041 cggtagaaat tggttcagaa atctgattga tgtactgaag ataagcttgt aagaagccga
    11101 tcgtcacacc acctgataga acaagcatag caccgaatac cgcacttatg atgaaggcga
    11161 gttgattaat gaaacgaatg gccggataga tagcacagtt cataaattga gcacgtttaa
    11221 aagcgttgta ttgcttttta tttacttcgt gtatagcagc ttctgcatga gcttgctgat
    11281 tgaatgtttt gaccactaga ttaccagcta agatttcttc cattcgatta tttaaaacac
    11341 ccagttcata ctgattctgt tcagaaatct gtttgttttt gttcgcaatc ttagttgtaa
    11401 caattgaact gccaacgatc agcaataaga cgagcaaagt aagcttgctt tcgatataaa
    11461 acagcatcag accagcagca gctattgtta cgacagaagt aaaaaattga ttgatacctg
    11521 tcaataacac ttgagaaagt tgattgagac cggtagttgt ccgactaatg atgtcaccta
    11581 cttgatgatt gtcaaaaaac gacatcggta atgttttgaa tttttttgtg atttcttttc
    11641 gcaccctcaa tgtgatcttt tcgcttaacg ctgccattgt ccgttcctga ataaatgaag
    11701 tgatgctgct taagactgaa cagccgatca gcaataagac agggaacaac aatgcttgtt
    11761 tgatatcact gaaagaaagc tgtccaatac ctgtttttct tatttctgat aagagatcat
    11821 cgatcccgat tcccatgatc aagggcatgg ctacgactaa taggttcccg aataaactgc
    11881 atagaaacaa tccgtaaaaa tatttatgtt caggtttgat cattttccaa aaacgtatca
    11941 aagcacgcgt gttcaacgtt tttttctttt ccatcgtatc ccttctttct atattccttg
    12001 tgattttgca aactcctgat aagtttggca attagacagt agttcttcat gagtaccttg
    12061 tccaacgatt tttccttcat ctaaaacaat gatgttatct gcttgttgga ttgtactgag
    12121 gcgttgagca acaatcacga gagttttctc cgacatgtgt ttatgaaggg ctgctcttaa
    12181 tgctgcatct gttttatagt ctaaagcgga gaaactatca tcgaatacat agatctctgc
    12241 tggtttgatc aacgctcgag caatacatat ccgctgtttc tggccccctg aataattaga
    12301 accgccttga gcaacaaagc tgtccaatcc gtcaggaagg gtgtccacta gttcttctaa
    12361 ttgagcgatc ttgatcgctt tagacaactc ttctgttgag gcatattcat ttcccatctg
    12421 caagttgctt aaaattgtcc cgctgaataa gaaagccttc tgagggacat aactgatgtg
    12481 ggagcggatc tgttcttgag tcatttgagt aagaggaata ccaccaaggg ttacttttcc
    12541 tatcgtaggg tcactaagtc tcaagagaag tttcgccaaa ctactttttc cagatccggt
    12601 cccgccaacg atcgctgttg tttttccttt aggtattgtg aaatcaatat cttctagaac
    12661 tggatcagag atttcagtat atttaaatgt gacatgttca aaagcagctg catttgtctg
    12721 atcaaaggtt ggttcagcta ctgttttgat cgtctcttcc tcaatttcga tctctgcttg
    12781 cagtatttct tctatccgtc gtaatgaggc aaacgattta gggataatga ccaataccat
    12841 agctgcgatc atcaagtaag caagtgtcag catagagtat tcgactacag cagtcacgac
    12901 accgatttgt aatgctcctt ctgctacaag atttccgcca aaccacaaaa tagaagcata
    12961 aacgattccc atgagcaaaa aagcaattgg agtgacccaa gcaaatattc ggttcacttt
    13021 gatcatttga ttagcatagt cagcaaagct cttattcgtt cgcttttctt catatgattg
    13081 attatcaaag gcacggatca tattaatccc agtaaagaat tctctcaatg tgatggtgat
    13141 ccgatccatt tttggctgga tactcaaaga taaaggtgcc cctcgtttca tcagtcgata
    13201 aacaatccat acataaaaaa caacagagat caatgtaacc catgttagta atagagaata
    13261 acgaaacatc atgagaatgg tgaaaacgca aataaccggt gctggtaaga tcatttggca
    13321 aaataaaaca atcatttgct ggacattatc gacatcattc gtcattcttg tcaaaagaga
    13381 tccagaacta aaacgactga tatccttcat tgacagctgt tggaatttac ggaaatattt
    13441 ctcccgcgtt tggaatccaa acctagcgga agccaatgct gaaaagtaac tagaggcaac
    13501 tgcagcgatt gttcctagaa acgctacaag cagcatttca actccaattt tttttataac
    13561 tgaggcttcg ccacttgcta tacctgtgtc gatcagcttt gctactaatt ttggtacacc
    13621 taatgtaccg gcgatttcta aacagatcat cacaaaggta aggagagcga gtcctttgtt
    13681 tttctgtaag aatgttttta agatagacat attattcctc cttttttcct gatacttttc
    13741 gattctatac cttcaagtaa cttgaaggtc aatagaaaaa agaataaact gaaaaagagg
    13801 tgagaaaaaa tgaaaaaaat gtatacgatt ggccaagtat cggaactatt tgatttgcca
    13861 aaatcaacga tccgctattg ggatgaacaa ggattaatcc gttcaagtag acaagaagag
    13921 aatgattatc gattgtttga tatcgatgat atttttatgc tttatgatat cgttttttat
    13981 agaaaattag atataccgat caaacagatg aagaatttat atggaaaaac attgacggag
    14041 ttatatgaga cacttgatga aacagaaaga agaatccata aagaactggt ggtgatgaaa
    14101 caaaaacaaa aagagataag ggagcaaaaa aaacagttga aattgatgat cgatacaaac
    14161 gaggaagaat ttcctgtaga agagatccct tttgactgta tgatctcaac ggagtttgaa
    14221 gatattgtgg aaatcaaaaa atttctacct aactattcaa gctttgggat gatgagtatg
    14281 ccagcttcca gttcacagac gatgtatgga ttttttatcg accctagtga agtacattta
    14341 tttactcaag acgtgatttg ggagaaaaaa gatacggctg tttatcgtcg attcttattg
    14401 aaatccgaga tgaaccatgc ggaacgtaat aatattttag aaatcagaga aagaatgtat
    14461 gaaaaaggat ggaaaacagg agaagtgatc ggccagtatc tattgacgaa tacggatgaa
    14521 aacaatatca gaactgaata ttatcatgca tggatagaaa tgaaaaaata ggaaatatgt
    14581 gtttaagata actcgaaaat gatggttgtt ttagttataa agaaaaattt tctggttcga
    14641 ttacgggttt aatgtggggg attattagtc gtggatagat agaattttag ttttttagag
    14701 gaaatatgtc tttaaaaatg gaatggttgc aattcttagc gatatatacg atgtaattgt
    14761 cctcttaaaa aagtatggaa aaataattgt attgggtgtt atgtataatt catggtgaac
    14821 tgagactaat gagaagaaaa attcatattg ttatgagtga gattgtatca gatgagaatg
    14881 ataaattaaa taggtgcata aaagcattac acttaaaata cattgttgct tacattatta
    14941 caatatgtta ataaggcaaa aataaataga tggattgaat aaacatattt tttaatcaaa
    15001 tagtccctac tgtgactttc ctcagctatc ggtgatacta ccgatagcat ttttttgctt
    15061 ataaaataat tataagtatt tagagatttt tcttctaaca ttcttcaaac aagaaaaatc
    15121 acaaaggtta ttgttatttt tatatattct ttttaagaat gattgttttt ttatagaaat
    15181 tttaaaaaat aaaacacgtt attgatggat agttagtttg ttatttggta atattataga
    15241 agttgactgg tagtga
//
LOCUS       DAZUJR010000069        15255 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.069, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000069 DAZUJR010000000
VERSION     DAZUJR010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15255
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.069"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            333..947
                     /gene="gmk"
                     /locus_tag="ACG804_002110"
     CDS             333..947
                     /gene="gmk"
                     /locus_tag="ACG804_002110"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFS4833031.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYINKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            952..1257
                     /gene="rpoZ"
                     /locus_tag="ACG804_002111"
     CDS             952..1257
                     /gene="rpoZ"
                     /locus_tag="ACG804_002111"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFS4833032.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            1510..3918
                     /gene="priA"
                     /locus_tag="ACG804_002112"
     CDS             1510..3918
                     /gene="priA"
                     /locus_tag="ACG804_002112"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HFS4833033.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            3933..4424
                     /gene="def"
                     /locus_tag="ACG804_002113"
     CDS             3933..4424
                     /gene="def"
                     /locus_tag="ACG804_002113"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFS4833034.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            4417..5355
                     /gene="fmt"
                     /locus_tag="ACG804_002114"
     CDS             4417..5355
                     /gene="fmt"
                     /locus_tag="ACG804_002114"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HFS4833035.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            5355..6713
                     /gene="rsmB"
                     /locus_tag="ACG804_002115"
     CDS             5355..6713
                     /gene="rsmB"
                     /locus_tag="ACG804_002115"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HFS4833036.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            6726..7466
                     /locus_tag="ACG804_002116"
     CDS             6726..7466
                     /locus_tag="ACG804_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HFS4833037.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            7463..9532
                     /gene="pknB"
                     /locus_tag="ACG804_002117"
     CDS             7463..9532
                     /gene="pknB"
                     /locus_tag="ACG804_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HFS4833038.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            9697..10596
                     /gene="rsgA"
                     /locus_tag="ACG804_002118"
     CDS             9697..10596
                     /gene="rsgA"
                     /locus_tag="ACG804_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HFS4833039.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            10609..11259
                     /gene="rpe"
                     /locus_tag="ACG804_002119"
     CDS             10609..11259
                     /gene="rpe"
                     /locus_tag="ACG804_002119"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFS4833040.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            11260..11898
                     /locus_tag="ACG804_002120"
     CDS             11260..11898
                     /locus_tag="ACG804_002120"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HFS4833041.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            12053..12907
                     /gene="mreC"
                     /locus_tag="ACG804_002121"
     CDS             12053..12907
                     /gene="mreC"
                     /locus_tag="ACG804_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HFS4833042.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            12911..13420
                     /gene="mreD"
                     /locus_tag="ACG804_002122"
     CDS             12911..13420
                     /gene="mreD"
                     /locus_tag="ACG804_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HFS4833043.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            13675..15249
                     /locus_tag="ACG804_002123"
     CDS             13675..15249
                     /locus_tag="ACG804_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NlpC/P60 family protein"
                     /protein_id="HFS4833044.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
BASE COUNT         5114 a         2864 c         3319 g         3958 t
ORIGIN      
        1 gtattaagcc aaatttatgc aaaaatgtga gaaactattt tcacaaaatt tttcttcata
       61 ctcgaaacta atcggcttct tcacgacctc ttatacacgg cgttcaaaag cttgcatctg
      121 cgataataac cccaaccaaa cgaaaaacat gagaagctgt ttatgtttgg ctgttcttat
      181 tacttgatgc aggacagctt ttttacgacc tcttggtaca gggtagcttt tttaccaatt
      241 tctagctata attaaagata accttgaaag ttgcagaaaa aaagtgcaaa ataaacgata
      301 agtacaaaaa gactagttga aaggacgtcg tcatgtcaga gcgtggatta ttaatcgtgt
      361 tgtctggtcc atccggtgta ggaaaaggca cagtacgaaa agcaattttt gagagtgagg
      421 ataatgattt tcagtattcg atctcaatga ctacccgtaa aatgcgtgaa ggggaggtcg
      481 aaggcgttga ttatttcttc cgaagcaaag aagagtttga atcaatgatc gaagctggag
      541 agatgctgga atacgcagaa tatgtcggga attattatgg aactcctttg tcatatatca
      601 acaagacatt ggatgaagga aaagatgttt tcttggagat tgaagtccaa ggagcaaaac
      661 aagtcaaaga aaaagtgccc gatggtgtat tcatcttttt gactccgcca gatttagcgg
      721 aattaaaatc acggatcgta ggccgaggaa cagatgcaga tgaagtaatc gaagaacgaa
      781 tgaaagttgc aaaagaagaa atcgaaatga tggctcttta cgactatgct gttgtaaatg
      841 atgaagtgcc gctagcagtt gaacgaatca aaaacattat tgccagtgaa cattttcgag
      901 tagatcgcgt aatcggtaaa tatattaaaa tgttaaagga gatgtagtct tatgatgtta
      961 aaaccttcaa ttgactcact attagatcgt gtaaattcaa aatattctct agtgatttta
     1021 gcaagtaaac gcgcgcatga attggatgca agtgcacagc ctactctaga ttcttttgat
     1081 tcagtaaaaa gcgtcggtca agctttagaa gaaatcgatg caggaaatgt agtcaatgat
     1141 ccacatcctg aattaaaacg tgaacgtttg aagatggaag aagaggaacg tcaagcacaa
     1201 aaagagcgtg aacaacacga attggaatca cgtatccgtg aagagcaaaa aatgtaataa
     1261 agaaaaatag agcgaacatc taaaaagaaa agcaaaccca gctgtttcct tttcaaacat
     1321 tcgccactta ttgtctggta gaaaaggctg tgtctgaact ttttgacaca gttctttttt
     1381 ttcttatctg ctgttaattt tttgttagga tttggcagaa gataagacaa atccatcgat
     1441 ctctagtaaa ataggcaagg aactttttgt cgcttgataa gaaaagacaa aaaaaggagg
     1501 aaacgaacca tgacattaac agctgaagtc attgtggacg tacctactat gcagaccgat
     1561 cagccattca cttatttggt tccctctgaa atggaaacag ctttgcaagt cgggatgcga
     1621 gtagaagtcc cttttggtaa tggcaatcgt catgtccaag gatttgttat ggctatccaa
     1681 aaatcagaag aatcagctaa tccatctttg aaggcagtta ttcgtttgct agaccttgct
     1741 ccggtggtca atgaagaatt actttcatta gctgattata tgaaaaaaat tacttacgca
     1801 ttcaaaatca cttgtctaca aacgatgctt ccgagtgtga tgaaagcaga atatgataaa
     1861 ttgatctatc ctttggcaga cacaccagaa gttcaggtat tgtttgatca gcgagaagtg
     1921 atttcctgga aggaagcaga agaagaaggc agcctttctc aattgattcg ctggcgccaa
     1981 gagcaattag tagatatcaa atatgaagtc catacacgaa ataaagtaaa aacgattcgt
     2041 ttggtccgtt ctttgttaac tgaaaagcaa atcgaagaag aatgggcaaa attacggcaa
     2101 aatgccaaga aacaaaaaga acttcttttg tgtttatctg aactgagcca agaagaacca
     2161 attgcttatt tcaaaaataa aggaatcagt actgctgtct tgaatcaagg aaaagaaaag
     2221 ggctggctgg agtttataga atcagaacgt tatcgcgacc cttataaaga ccgagtattt
     2281 gaccaaacga cggcattgga actgaatgca gaacaaaaaa atgctgtcga acaaatcatc
     2341 acagcaggtc agcagcaaaa agatcaggtc tttttgctgg agggaatcac tggcagcggg
     2401 aaaacagaag tatatcttca ggcaatcgct gatgttttgt cagaaaataa aacggctatt
     2461 atgttagtgc ctgaaatcgc attgactccg caaatggtcg agcgattcaa aggacgcttc
     2521 ggagaatcag ttgcggtctt acatagcgga ctttcccaag gtgaaaaata tgatgaatgg
     2581 cgcaagattg agcgggaaga agcgcaagta gtagtaggcg cacgatctgc tatttttgcc
     2641 ccgctgaaaa atatcgggct gatcattatc gatgaagaac atgaatcaag ttacaaacaa
     2701 gatgagacac cgcgttatca tgcgagagat ctagcaattt ggcgcagtaa atatcatcat
     2761 tgcccaatag ttctaggaag cgcgacgccc tctttagaat caagagcacg agctcaaaaa
     2821 ggcgtttatc agttattgca gttaaaccac cgagccaaag cagctgcaca gcttccagct
     2881 attgagatcg tagatatgcg tgaagagttt cagaatcatc ggacctctac tttttctgct
     2941 aatttgcagg aaaaaataca aaatcgatta gacaaaaaag aacaaactgt cctactgctc
     3001 aatcgtcgag gatattcgtc ttttgtgatg tgtagggact gtggatttgt tcttccatgt
     3061 cctaattgcg atatctctct tacactgcat atggatacac gttcaatgcg ctgccattat
     3121 tgcggacatg aagaacctat tcccaatcgc tgtcctaatt gtggcggcaa taaaatccgc
     3181 tactatggaa caggtactca aaaagtagaa gaggaactcc gagaacttta tccgcaagct
     3241 aggattttgc gtatggatgt agataccact cgaagaaaag gggcacacga acagatttta
     3301 caaaaattcg gtgcaaaaga agcagatata ttattaggga cacaaatgat tgctaaaggt
     3361 ttggactttc cagaagtgac attagttggg gtgttgaatg ctgatacctc cctgaattta
     3421 ccggattttc gttctagtga gcatacattc caattgctta cccaagtttc aggacgagca
     3481 gggcgagcgg aaaaagcagg cgaagtcgtg atccaaacat tcaatcctca acattacgcc
     3541 atagaattag ctaaaaaaca aaattatgag cagttttatc agcaggaaat gcatgtacgg
     3601 catcgtggag gctatcctcc ttattacttt actgtgaaaa taaccgccag ccatcctgaa
     3661 gaacaagtag cggcaaagaa aatctttcag attgccaatc agctaaaaga agtgttaagc
     3721 cctcaaagct tgctattagg gccaacgccc agcatgattt tgagagtgaa aaaccgatat
     3781 tattatcaac taatcatcaa atataaacat gaaccgaatc ttcctcatgt tttggatgaa
     3841 attttgaatg gaagccagaa agaacagcga caaggtcttt ttgtggcaat tgacaacgaa
     3901 ccattaaact ttatttaaga aagggccaaa ttatgcgcta tcctatattg atccacccta
     3961 atgataaatt aaaaagaact gctcagccaa tcgatgtaat cacggacgag acaatcgctt
     4021 tattagacaa tttatatgag acaatgattg cgaatgacgg aatagggatc gctgctcctc
     4081 aagtaggaca aaacaagaga attgctgtga tcgaagtaga tgaaggcgag aaatttgaac
     4141 tgattaaccc agaaatcatc gaagcaaaag gtgaaagcct tgacgtagaa ggttgtctca
     4201 gtattccgca tgtctatgga acggtcaagc gagcagatga agtgaccgtg cgttattatg
     4261 atcgagacgg agaagagata gaagtgacgg cttttggcta tttagcccgt gccttccagc
     4321 atgaaatcga tcacttagac ggtatcttgt tcattgagaa aatgatacag cagatcccgg
     4381 aagaagaact tgaagaatat atggaggaac atcttgatga ctaagctagt atttatgggc
     4441 acacctgctt tttctgtgcc gattcttgaa gggctgatag aatcaggtta cgagatccag
     4501 gcagtggtaa cacagcccga ccgtccagtt gggcggaaac gagtaattac gccgacaccg
     4561 gtaaaagaag cggctctgaa gcacggtatc cgtgtgctgc agccagagaa aatctccggt
     4621 tcgccagaaa tggaagaaat cattgaattg gtgcctgatg tgatcgtcac tgcggcattt
     4681 ggccaattct tgcctgaaaa gttattgcaa gtaccaaaat taggggcaat caatgtccat
     4741 gcttctttac ttcctaaata tcggggaggt gcgcctgttc attatgccat catgaatggg
     4801 gagaaagaaa ctggtgtaac gatcatggaa atgatcaaaa aaatggatgc aggcggaatc
     4861 tatgcgcaag aaagcatacc aatcactaaa caagatgatg tagggacgat gtttgaaaag
     4921 cttagccttt taggaagaaa gctattgcta gaaacattgc ccaatatttt ggatggacaa
     4981 aaaccagtac ctcaagacga gtcagaagca actttttcgc caaacatcac acgggaacaa
     5041 gaagcaatcg attggcataa aactgcagaa gaaattgaca accaagtacg cggaatgcgt
     5101 ccttggccaa ttgcattcac gacctatgag ggcatacgct ggaaattatt atcggttgaa
     5161 gtattggcag aaactacaga caaagcacct ggtacgatca tccggaaaga caaaaaaaat
     5221 ctatggattg cttgcggtaa acagaccgtc ttagccatca atgaattaca gccagctggt
     5281 aaaggaaaac aggccgtaca tgatttcctt aacggaagcg gtcagcaagt tcagattggt
     5341 cagcaggtga aataatgaaa aaaatcccta aaaaaatgaa aaaatcagta cgatatatgg
     5401 cattactgac attagagcga gtgaacaagg gtggcgccta ctcgaatctt ttgttgaatg
     5461 agatgatcaa acaaagcgag ctaaatcaaa aagatgtggg tttatttaca gaattgatct
     5521 atggtacgat tagccatcag cgactattgg aattttacgt tgcaccattg atcgctaaag
     5581 caaaaaaagt ggatgactgg gtcaagacgc ttctttatct ttctgtatac caattagaat
     5641 ttttagataa agtccctgca catgctattt taaacgaggc ggtcgaaatc gcaaaagtaa
     5701 aaggaaatcc tgggacaggg aaatttgtaa atggtgtctt gaggaattat cagcgtcaag
     5761 gagcaccaga tctgcaaggc attgctgatc ctatcgaaag actttctgtc aaaatcagcc
     5821 tgcctctatg gatgacgaaa cgactggtgg atcaaatcgg atacgaagaa actgaaaagc
     5881 tcggtttatc gctatatcag cctagccatg ctagtgcccg agtagataca cgccgacttt
     5941 ccagagatca ggccatcact gttttgcaag aagaagagat cacagctgaa aaaagccaag
     6001 tcagtccata cggtatagta gcgaaaaaag ggcatttagc ttctagctca ttgttccacg
     6061 atggcgtcat gacgatccaa gatgaaagtt cgatgcttgt agcgccgtct atgcaaatcg
     6121 agcctgaaca tcatgtctta gatgcctgtg cagcacccgg aggtaagacg acgcatattg
     6181 cttctttttt agatccgtca tgcggtggag aagtggtcgc tttagatgta cacgaacaca
     6241 aagtcaaact cattgaagat aatgcagcac gtctaggtgt ctcttctgct gtctacgctc
     6301 aaaagatgga tgctagagaa gtcagtaaac agttcgaagc agagcagttt gatcggattt
     6361 tagtagacgc gccttgttca ggtcttgggc tgcttcggcg aaaaccagat attcgttata
     6421 aaaaacagcc ggatgaatta gcgaatttac caaaaatcca attggaaatt ttagaaagct
     6481 gcgcaccaac tttaaagtct tccggtattc tgacttatag cacttgtacg atcttaaaag
     6541 aagaaaacca agacgttgtt tctgctttct tggaaagaca ccctgatttt gagaggattg
     6601 atgttttgac caatcctatg ctacaatcat caatcgaaga gaaaatgttg actttgtatc
     6661 cgcatcagtt ttacacagat ggatttttca tttgttgttt gcgcaaaaag taatgaggtg
     6721 aaaaaatgca gattgaatat caatcagatg taggaagacg acgtaacaca aatcaagact
     6781 atgccagtgt atttaccagc cgttcaggtc tcaagcttgc tgtattagca gacgggatgg
     6841 gtggtcatcg tgccggagac attgccagtc agatggcggt aacgaatcta ggcgaagctt
     6901 gggaaaaaca agaagctgtt gacgatgaaa aaatcgccca atggttcatt caatcgattc
     6961 aagaagaaaa tatgctgatt tatcagcgtg gacaagaaca gccggaatat aacggtatgg
     7021 gaacaacaat cgtagcggcc gctctgtcag atgactggtt cacgattgcc aatgttgggg
     7081 atagcagagc ttatttgatt cgtgaagata aaatcatgca attgacggag gatcattctt
     7141 tagtcaatga actagtcaaa tcaggagaaa tcagcgaaga aatggcagtg aaccatccaa
     7201 ggaaaaatat tttaacacgt tctgtcggca tgcctggaac agtcgaagta gatgtttcta
     7261 ctcatctttg gcaactaaaa gatcgactgc tgttatgttc agatggcttg acgaacatgc
     7321 tgtctgaaga agaaatagga acgatcatca atcaagaagg cccattgtct cataaagtaa
     7381 ctgagctgat tgatcgtgcc aatgaagcag gcggagcgga taatatcacc gttcttctta
     7441 tcgaatataa ggaggacagt gtatgatcga gttgggcaaa aaattaaatg gccgttatca
     7501 aatcactgga aatatcggta gcggtggtat ggcaaatgta tttttggcgc acgatttaat
     7561 cttggatcgt gatgtagcag ttaaagtctt acgatttgac tttcaaaatg accagactgc
     7621 gattcgacga tttcagagag aagctttagc agcaacagaa ctcgttcatc caaacattgt
     7681 tagtgtttac gatgttggtg aagaagacaa catgcagtat ctggtgatgg aatacgtcaa
     7741 aggaatggac ttgaaacgat atatccaaac acattatcct gttccttatg aaacagcagt
     7801 aaatattatg cagcagatcc tttctgctat ttctttagct cataaccatc aaatcatcca
     7861 ccgagatttg aaaccccaaa acgtactgat cgataatgaa ggtgttgtaa aaatcacgga
     7921 tttcgggatt gctatcgctt tatctgaaac atcgatcacg cagacgaata cgatgctggg
     7981 atctgttcat tatctgtccc ctgagcaggc cagaggaagt atggcaacga agcagtcaga
     8041 tatttatgct ttagggatca tcctttatga gatgttgacg ggtagcgtac cgtttgatgg
     8101 tgaatctgct gtaacaattg ctttaaaaca ttttcaagat gatcttccat ctataaaagc
     8161 acttgatcca aatgtgccac aagcactgga aaacgtgatt ttacgggcaa cggctaaaga
     8221 acctgcagac cgttataagt cagccgagga aatgtctgat gatctttcta cagtattatc
     8281 accagctcgt gcaaacgaag aaaaatggca gcctcatgtg atggataatg aaacaaaagt
     8341 tatcacaccc cttacggaag atgcaccaat gcctgattca ttcaaatcta tgcctctgcc
     8401 aaaagacaag ccagaaaacg aaaccttgcc agaggaggaa gaagttctgc ctgatcctaa
     8461 aaagaaagga cagaaaaaat ggtggctgat cctattagct attcttgctg ttttaggaat
     8521 cggaacagct gtattctttg cttctggcgg gcgaggagaa gttgttgttc ctgatgtttc
     8581 tgatctttct gaagcttctg ctagagaaac actcgcaaaa gcgaaattag aagtagcaac
     8641 aaaaacagaa gaaattgcag atgacaaaat cgaagaaggt aatgtagtga agacagaccc
     8701 ggcagcggga acgacagtca agcaaaaacg cgaagtcact ctgtatatta gtagcggcac
     8761 gaaaaaaatc aaattagatg attacagtgg taaaagttat gaagatgccg aagcaagttt
     8821 gaaagaatta gggttttctg ctgacttgat tcaaaaagaa gaggaattca gttcagaggt
     8881 agaaagcgga atgatcattt cgcaatctcc atcagaagat acagaagtcg atcctaaaac
     8941 agacacgatt actttcacag tcagcaaagg accagaaaca gtgactttga gtagtcatgt
     9001 aggagaaaac tacgaaactg ttcgtaattg gcttgttaca caaggattca atatcaataa
     9061 tattagtgct acttatgact atagcgacac tgtaccatca ggttcgatca tcagtcagga
     9121 tccagcctcg ggtgaagttg tagcagaaga aacttacatc aattttgtcg taagccaagg
     9181 aacagagcct aaattgaatg atatctccgg ctatacaaaa agcgaagcac aaagttattt
     9241 agctagtgtc ggtgcagaat atatcgggca tgagacttcc gaatattcaa acacggtgga
     9301 taaagataaa gtgattcgta cagtaccagg ggcaggaacg acaattacca aaggaatggt
     9361 tgtgaacgta atttactcta aaggaccaga tccagcgtct tctagttctg aaaaagactc
     9421 ttcagacagt tctagcagct caagtagctc cagtagcaca agcaactctt caaaagaaga
     9481 atcttccagc tccacaagtt catcagctag cacctcagaa agttcaaaat aagtgctgaa
     9541 taaaatatat cagaagggaa tgcgacattg atttgttgca ttctcttttt tgtgtttcta
     9601 tctcttttga tcaattttca agccatatac tttgagaagt ttgcatggaa taacacctac
     9661 tttcctcttc gtatggtaaa ataaacaaaa acggaggtgg cacttatcaa aggacaaatc
     9721 agaaaagcaa tcagcggttt ttactatgta tacgcaaacg gagagaccta tcaaacaaga
     9781 ggaagaggaa atttccggaa tcggaaaatc acgccgcttg tcggagatca ggtgatcttt
     9841 gagagtgaaa atcaaacaga cggctatctt ctggaaatct tgccgagaaa aaatcaatta
     9901 gttcgcccac cagtcacaaa tgttgatctt ggaatcattg tcacaagtat cgtagagcct
     9961 gcattttctt ataatctact tgaccgcttt ctagttacct tggaatacga gtcgatcgaa
    10021 ccgattattt ttttgacaaa gaccgacttg tcagacgacc cagaaaaaat cgaagagatc
    10081 aagcaaacct atactaaaat aggctatccg gtgattgtac ccaatcatac gggtgatacg
    10141 acagaactga tccgttactt cccagaacgg ctatcggtct ttatgggtca gtctggagca
    10201 ggaaaatcga cgctactgaa tcaaatatca ccggaactga atttagcaac aggagagatt
    10261 tctgatgcac ttggaagagg acggcataca acacgtcatg tggaactgat tcctatctat
    10321 ggcgggttag tagcagatac accaggattt agctcgattg actttttgac aattgaagca
    10381 ggagaactgc cgagacaatt tcctgaattt gtagaagctt ctgtccattg caaatttaga
    10441 gagtgcatgc atgctaaaga acctggctgc gaagtaaaac atagagtaga aacaggtggt
    10501 atcgcacaga cacgttacga caattatttg caattcttac aagaaatcga aaaaagaaaa
    10561 ccaatgtatg caaaaaaaga aggtaaacga aaataggagg aaacaagaat gaagatagca
    10621 ccatccattt tgagtgcaga ttttgccaat ttacaaagag acattgagtt agtggaaaaa
    10681 ggaggcgcag attacatcca cgtagatgta atggatggcc aatttgtccc aaatatcaca
    10741 ttagggccaa atattgttca ggcaatccgt cctgttacta aattaccgtt agacgtccat
    10801 ctgatgatcg ttgatccaga aaactacatt ccagcatttg caaaagctgg agcagatatc
    10861 attactgtcc acgtcgaagc aactcctcat attcatcggg cacttcaaat gacaaaaagc
    10921 ttaggagtta aagctggagt agttatcaat ccaggaacac cagtctccat gatcaaacat
    10981 gttttgcctt tggctgatca agtactagtc atgactgtca atcctgggtt cggcggacaa
    11041 agctttattg aagaaacagt agaaaaaatt acggaactcg ctgatctacg tagagagaac
    11101 aattggactt atgcaatcga agtagatggc ggaatcgttc cagaaacagc aaaaatctgt
    11161 aaagatgcag gggcggatgt cttcgttgca ggatcatata tctatggagc cgaaaatcca
    11221 gtcggacaaa tcgaacgatt aaaagaggca ttagactaaa tgaaaatttt attagctgct
    11281 ggaggtaatc cgcaaaactg gccgcagtct ctgctgtcca aatacgatgc ctatgtcggg
    11341 atagaccgtg gtgcgctgta cctgcttcaa gcaggctacc cagtagatct ggcagtgggc
    11401 gattttgatt cattgtcgaa cgaagagcag aaggaagtat ttgcaaaagc caaagagtat
    11461 acccgttccc ctgcagaaaa agacgataca gatacacagt taggtatctt aaaaacattt
    11521 gaacgttacc cgcaagcgga agtcactttg attggagcta cgggcggaag attggatcat
    11581 cttttagcca atctctggtt aggtatggaa cctcgcttca aaccctttgc ccatcagctt
    11641 attatcagag attgtcaaaa ttatttgtct tattatttgc ctggagagca tatagtaaga
    11701 cagataccag atatgaagta tttagcttat tgctgcttga ctcccgtctc gaatcttaca
    11761 ttaaaaggca gcaagtatgt attggaaaat aaagaagtag aatatccgac atcttatgca
    11821 agtaacgaat ttctttcaga taccgcagaa ttttcttttt cagatggtat gattgcagtt
    11881 attcaaagca aagattgatc cataaacaaa taaaaaaatt tgtctttcag gctaaaaatg
    11941 acagaatcta ttatttgcta aaaaaaagct taagaggagc aacttacctt ttgtttcacg
    12001 gcatttagtg ataaaattga acacaagagt ctaattaatt cgaggtgtct ttgtgaagaa
    12061 gttcaatcct aataaaaata ttattattac cttggttatt gttatcatcg tggtgacgat
    12121 actaagtgtg accgctgcgc agcgagcgaa tgaaggaaag cccaatttct tccaatccat
    12181 cgttaatgac agtgttgcaa tggttgataa aacaatctct gccccagtac ggtgggtacg
    12241 aaatggagta gattctgtcc ataatctttt ttcaacttat gccgaaaatg agcggctaaa
    12301 agaaaaaatc gatagctatg atgacgtttc acagcaaaac aagaattacg agagagaaat
    12361 cgaagcgttg aaaaaagaac ttgagttgaa tcagacgctg actagttacg aaaaagtaac
    12421 ggcaaatgtc attactcgtt cgcctgacag ttggcaggac atgctgatcg tagacaaggg
    12481 ttctaaagac ggtatcgaag caaatatggc agtcatgtcg caaaaaggat tgattggccg
    12541 agtgatcgag gtcaatacgg cttcgtctaa aatcgaatta ctgtcatcct ctaatgaaag
    12601 ctccaatcat tttccagtac gggtatcttc ggctaatggc gaagcgtttg gtttgcttaa
    12661 aaactatgat gaaaagctcc atgccttagt ggtgacccaa ttaactggtg atacggatat
    12721 caaagaaggg gatgttgtcc agacatccgg tcttggaggg aattctccag ctaacttgcc
    12781 gatcggtacg gttattaaaa cgaaaccaga tagttatggg ctggatcggg aagtttatgt
    12841 gaaaccttat gcagaaatgt atgacgtgtc agttgtgacg attgtccaac ggctagcgga
    12901 ggattagtcc atgttgaaga aagaaacaat gaagtactat ctgccaatcg ttttgttctt
    12961 tttgatgttg atagatggtc atttaacaag aatgctaggg gagtggtcga aaggcaccta
    13021 tatgtcaaat gcccactttc tgatattggc attattatgt tgcagtatgg cgtttgaaaa
    13081 acgttattta ctgattacca cgattgttct cggggctatc tatgacgctt actatattgg
    13141 cgttatcggt atctatgcag tagctctccc tttaattgta tggttgatgt atgtaatgaa
    13201 agacgttatc catgtcaaca tctttactga atttttcagt atgatcatct ttgtcacggg
    13261 ttatgaattg tttacgatgg tggtccagtt gatttttaaa ttagcagtag taaataacac
    13321 gtattttatt acaaggtttt taggacctac actgctgttg aacatgatta tatttgtatt
    13381 attcattttt ccctttaaga aattattcag tgatgaataa tttctttttt tatttttagg
    13441 tcgaaagcga aaaagaatcg ttgttatctt aagaaatgct agacttaacg cggctttttc
    13501 atgatcattt tctgaaacga acagttttgt catttttaaa agttgttttg aaacattttt
    13561 gtaacataac tattatatcg ttgacacact gctatggtac aatttttata tcgttaagaa
    13621 agacttaaat atatttagat atttattaaa ttaagccagt cggaggaatg aagagtgaaa
    13681 aagagtttaa tatcagcagt aatggtatgt tcaatgacct tgactgccgt agcatcaccg
    13741 atcgctgccg cggcggacga ttttgattct cagatacaac agcaagatca aaagattgca
    13801 gacttgaaaa atcaacaagc agatgcacaa tcacaaatcg atgccttaga aagccaagtt
    13861 tctgaaatca acacacaagc acaagaccta ttagcaaaac aagatacatt gcgtcaagaa
    13921 tctgcacaat tagtaaaaga cattgcagat ttacaagaac gtattgaaaa acgtgaagat
    13981 acaatccaaa aacaagcacg cgaagcacaa gtaagcaaca caagctcaaa ctacatcgat
    14041 gctgtattga atgctgattc attagcagat gctattggac gcgttcaagc aatgacaacg
    14101 atggtaaaag caaacaacga cttgatggaa caacaaaaac aagataaaaa agctgtagaa
    14161 gacaaaaaag ctgaaaacga tgctaaacta aaagaattag ctgaaaacca agctgctttg
    14221 gaatctcaaa aaggcgatct tttatctaaa caagctgatt tgaacgtact gaaaacttca
    14281 ttagctgctg aacaagcaac tgctgaagac aagaaagctg acttgaaccg tcaaaaagca
    14341 gaagctgaag cagagcaagc tcgtattcgt gaacaacaac gtctagcaga acaagctcgt
    14401 caacaagctg cacaagaaaa agctgaaaaa gaagcacgcg aacaagcaga ggctgaagca
    14461 caagctactc aagcttcatc tactgcacaa agctcagcaa cagaagaatc atcagctaca
    14521 caatcttcaa tgactgaaga atcatcatca gctacacaat cttcagcaac agaagaatca
    14581 acaacacctg aatcttcaac agaagaatca acagcgcctg aatcttcagc aacagaagaa
    14641 tcaacaacag cgcctgaatc ttcagcaaca gaagaatcaa caacagtgcc tgaatcttca
    14701 gcaacagaag aatcaacaac agtgcctgaa tcttcaacaa cagaagaatc aacaacacct
    14761 gcgcctacaa caccatcaac agatcaaagt gttgatacag gaaacggcac aggaagtagt
    14821 actccggctc caacgccaac accaacacct gaacaaccaa aacctgtaac acctgctcca
    14881 gctccttctg gaagtgtgaa tggtgcagca atcgtagcag aagcttacaa atatattggt
    14941 actccatatg tttggggcgg taaagatcca agtggctttg actgctcagg gttcacacgc
    15001 tatgtttaca tgcaagtaac tggtcgtgac atcggtggtt ggacagttcc tcaagaatca
    15061 gctggaacaa aaatttcagt ttctcaagca aaagctggag acttgttatt ctgggggtca
    15121 caaggcggaa cttaccacgt agcgattgct ttaggcggag gacaatatat ccatgctcct
    15181 caaccaggcg aaagcgtaaa agttggttca gttcaatggt ttgcccctga ctttgctgtc
    15241 agcatgtaag aatga
//
LOCUS       DAZUJR010000070        15139 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.070, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000070 DAZUJR010000000
VERSION     DAZUJR010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15139
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.070"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            5..2377
                     /locus_tag="ACG804_002124"
     CDS             5..2377
                     /locus_tag="ACG804_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArdC-like ssDNA-binding domain-containing
                     protein"
                     /protein_id="HFS4833045.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQKMTNGQ
                     PMNDKRNGRSWFNQQERIENKVQSLREEIKQQEEYVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESAFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     RPTDSMKEKENDHFYRVEFNENDPEKGLKSYGGEIVTFELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTLETPENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2438..3898
                     /locus_tag="ACG804_002125"
     CDS             2438..3898
                     /locus_tag="ACG804_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HFS4833046.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQIKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            3909..6113
                     /gene="topB"
                     /locus_tag="ACG804_002126"
     CDS             3909..6113
                     /gene="topB"
                     /locus_tag="ACG804_002126"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFS4833047.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQVGADQGKTFKRLWINSLEKEAIYQGFQQLRDAKETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKSEVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGMIRQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLRAEEISTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTEATYES
                     LTPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGVLLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSIDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            6129..6278
                     /locus_tag="ACG804_002127"
     CDS             6129..6278
                     /locus_tag="ACG804_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833048.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKLRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            6353..6946
                     /locus_tag="ACG804_002128"
     CDS             6353..6946
                     /locus_tag="ACG804_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HFS4833049.1"
                     /translation="MQEKLKELLAIRDGNLSMKEARKLGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEIEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            6959..7858
                     /locus_tag="ACG804_002129"
     CDS             6959..7858
                     /locus_tag="ACG804_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HFS4833050.1"
                     /translation="MTPTQFAAKTRNLAKRTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTAQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIIGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            7861..8358
                     /gene="ssb"
                     /locus_tag="ACG804_002130"
     CDS             7861..8358
                     /gene="ssb"
                     /locus_tag="ACG804_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFS4833051.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMVTLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSTSPSTTTFEQRDTATPNNNGLNALQNPFGNPFGGQSIDISD
                     DDLPF"
     gene            8724..8984
                     /locus_tag="ACG804_002131"
     CDS             8724..8984
                     /locus_tag="ACG804_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833052.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            9429..9635
                     /locus_tag="ACG804_002132"
     CDS             9429..9635
                     /locus_tag="ACG804_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HFS4833053.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGQRAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            9656..9886
                     /locus_tag="ACG804_002133"
     CDS             9656..9886
                     /locus_tag="ACG804_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833054.1"
                     /translation="MTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLVEDAPTML
                     FEDLVKIAGYELHYQENMETYENEYWLTKLEN"
     gene            9902..10339
                     /locus_tag="ACG804_002134"
     CDS             9902..10339
                     /locus_tag="ACG804_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833055.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYGKFVETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            10332..11039
                     /locus_tag="ACG804_002135"
     CDS             10332..11039
                     /locus_tag="ACG804_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833056.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKHRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSCTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATIDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKRQ"
     gene            11203..11403
                     /locus_tag="ACG804_002136"
     CDS             11203..11403
                     /locus_tag="ACG804_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833057.1"
                     /translation="MNKIIPLLFVLCIGEILMRHGAAVHLNFVVFLGILVFCLIFWRF
                     VLALVSLLFKLIAAIFFIGLFR"
     gene            11419..11598
                     /locus_tag="ACG804_002137"
     CDS             11419..11598
                     /locus_tag="ACG804_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833058.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
     gene            11923..12186
                     /locus_tag="ACG804_002138"
     CDS             11923..12186
                     /locus_tag="ACG804_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HFS4833059.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            12180..12530
                     /locus_tag="ACG804_002139"
     CDS             12180..12530
                     /locus_tag="ACG804_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFS4833060.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(12554..13168)
                     /locus_tag="ACG804_002140"
     CDS             complement(12554..13168)
                     /locus_tag="ACG804_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFS4833061.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            13482..13904
                     /locus_tag="ACG804_002141"
     CDS             13482..13904
                     /locus_tag="ACG804_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833062.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            13914..14117
                     /locus_tag="ACG804_002142"
     CDS             13914..14117
                     /locus_tag="ACG804_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833063.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            14328..14912
                     /locus_tag="ACG804_002143"
     CDS             14328..14912
                     /locus_tag="ACG804_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFS4833064.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT         5571 a         2451 c         3061 g         4056 t
ORIGIN      
        1 gaacatggca gaagaaaaag aaccactaga caatagtcgt ttgggaaaat ccaaaagaaa
       61 actagtacga ttgcaaaatg aattaaacga acaaattgaa aagatgtttg aacaccaaaa
      121 aatgacgaac ggtcaaccaa tgaacgacaa gaggaatggc cgttcatggt ttaaccagca
      181 agaacgaatc gaaaataaag tccaaagtct gagagaagag atcaagcaac aagaagaata
      241 cgtggaaaag cttgaaagac aagaagagct aaaggaaatg ggctataaca agtacggcgg
      301 actggatatg acgatcgata atattccaag aatcaaagaa gaaatcgaac gctttgaaaa
      361 aggtgaatcg gctttttcag ccgccacgat ccgaaaatac caacggaagt tggaaacatt
      421 agaacagctg aaagaaaaat cagaaaaagg aaaagaaaat atcctccctg aagtacaagc
      481 gatcattgac agcggacgag tgacgcaatg gaaaaaaaat ccaaccattt attttttgaa
      541 aggctatcga aaagttgctt tagaactgaa tgaaaacggg ggatttgagg aatcaaaaaa
      601 ataccaagcc acgtcggaag aggaaaaagc agctgttcgt gaattacttg aagaggctag
      661 accaactgat tctatgaagg agaaagaaaa cgatcatttc tatcgagtag aattcaacga
      721 aaatgatcca gaaaaaggat tgaaaagtta tggtggggag atcgtaacat tcgaattgat
      781 cgatcaactc aaaacattgg ataaccaata cgccgcagaa gcaggttatt ataaattcta
      841 ttttgaggaa gtgaagaacg gagaagtagt cgatcagatc cgaatggatc taggggatgg
      901 cgtcaacagt aatcaaccaa tctatttaga gttagcaaaa ttgtgcgaac aagtacctga
      961 gaaggaacaa aaacaatcgg tcaaaaatga acctgtttcg aaagaacaaa tgcagtcgaa
     1021 agaaacaaaa acaaaacaaa agggctatca aaaacgaacg gcagaagaga ttaaacaaga
     1081 agttaaatcc ctttcgcaac aggcactgga tgcggtgaaa aagcataccc attctcctga
     1141 agacgtcaaa gaacttttga actttatgtc tcgttttcca gaacgatcct ttagaaatca
     1201 attattgatt gaggaacaat ttccaggtgc aacggcttgt ttaggtcgtg ccgcgttgaa
     1261 aaaagaagga atctatatca aaaaagggga acaagggaac aagatctttg tcagaaaaac
     1321 ggtcaaaggg ttttatgaga aaggacgtgg ctttgttcga gaaacagaag ctacaccaga
     1381 agataaaaaa cgaatcgaaa gtggtcaaat cgaagtgatc aaaaaacctt actatacgat
     1441 tgaaaaagtg tttgatatca cacaaacaca gttaaaacct gaagactatc cgaaaatctt
     1501 tccgaaccgt gtctttgatt ttcaattgga taaaaaagga cagtcagaac ttcaagctgg
     1561 gattcaagcg gtagccaaca atattggaat acaaattcga gatatgacag aaagtgaagt
     1621 ctatcaaaga gaattaggac aagcacgtgg ggcgtatgtt cgtaacgaat ttactggcga
     1681 agaagaaatc gtcatgaata ctcgaaatac tcctacgcag catttagcta caagtattca
     1741 tgaattagcc catgcaagaa tgcacaaatt ttcagaatta gataccgcaa ctaaagaatt
     1801 gcaggcagaa atgacttctt atattgtgtg caaacatttt ggaatggaca cgtcggagaa
     1861 agctattcct tatattgcag catggacgaa gaatggtcag acgttggatg ataaggaagc
     1921 tgcggaacgt gggaaaatca tgaatgatgt cagccgtgtc gcaaatgaat tcattcaaac
     1981 catttctaat gaaatcaatc aatacagaga aagagaacca gagatccaac cagcagaagt
     2041 gaagcaggag cataaaaata ctttagaaac gccagagaat aagaatattg tgcccgttgg
     2101 ttcactttgg atcgacaaga aagacgggaa agtaatggaa gaagatacgg gtcgaacgtt
     2161 acatttgaag gatgcggcgt ttattgaaga tccgcagcat aatcaagtaa ttttaaaagg
     2221 aaaaagttat ggaaaagaga tccaaacggc gttaccttca gaagaatttg cgctaggaaa
     2281 tccattccga ttttcacttg agacagtgtc agaagtggca aaacgaaaaa atgaaatcta
     2341 ttatgaacaa caattgtcac aaaaagaacg tgtataaaac aagtaaaaaa gactatctga
     2401 aaaacggata gtcttttttc ttttgggagg ttttaaaatg accgagaaaa aaatgagtct
     2461 tattgatcga tgtaaacaga tcgatatagt ggattttgct cgaaacaatg gaatggctgt
     2521 agtcaataaa ggacgagatt atcgcttaga agaccatgat tcatttgttt ttgatcgaag
     2581 aaaacaacgt ttttattgga acagtcaaaa tattagtggc gacattattg aattagctaa
     2641 actttttttc atagacaaag agatccaaga ccctaagcaa caatttaaag cagccactga
     2701 ttttattcta aagaatgaag acaaaacaga acgagtggaa aatcttcatt ttgaaacaga
     2761 aaagtacaaa gatcaccccg ttgattatca accactcaca gaaaaaggaa ggaattatct
     2821 gaaggaagaa cgaaaactac cagagtggct gattgattat gcagaaaaag aagggttgat
     2881 tgccgaacta aagccaaaat atgaacggca aaatttctta gttcgagacg atcgtttaga
     2941 tcatgcggtc gcctttttat ggaaagatcc acagacaaaa gagacagtag gggcgagtta
     3001 tcaaggaacg ttcattgatt atgaacgttt tggtgagaga ggcacatata agcatataga
     3061 taaaaattcg acagcgaatc atggctttaa cctaaagatc ggtgacccta agcagataaa
     3121 attttttgag agtagtattg atttacttag ctatgctgca ctgaatcgtg atcagttaaa
     3181 cgatacgtgg ttagtctcta tggaagggtt aaaacaccat gtgatcagtc attattttgg
     3241 tgaggcagta tctgaattga gaaagaaaca agcctttcct caatccatcg agatttgtgt
     3301 ggataatgac cgtgcaggac atattttcta cgaaaaagaa caattaatgg gcgcagtcga
     3361 tccatttacg aatcagaaag tacgttgtga acgaggaatc gctaatgatt ggcaagtgcc
     3421 aaaagaatac aaaatcattt atgaagaagt cgcaaaagaa gaaaaggtca caccagaagc
     3481 tattatggcc atacacaaga cagaaaacaa tctgcaatta acgaaccaac tggtttccgc
     3541 tcacaaagta aatgcgtttt ttggccagca gctttctgtt aacgattcaa tagaagccat
     3601 taatttgaaa gatatttgta gagaagtcgc aaaagaatta aaagtttgtg aacgcgtgga
     3661 tggtacgtac gattttgatc gtttttatca agaaaaaggg gatattaatg cgcagattct
     3721 tttctcttat aaagcagaac aatactacaa aggctataaa aatcatgaac atgaatttgt
     3781 acctgaagta aaaaaggact ggaacgatca attgaagcat gagatccagc aacaagaaat
     3841 cagaaagcaa aaacgtgcca tgttgtttca acaaggcaga caacaagaaa gggagtgaaa
     3901 tcgtcatgat gaaaaccgtt attttagcag aaaagccgtc acaagcgaaa gcttatgccg
     3961 atagcttctc taaagccact cgaaaagacg ggtattttga aatccaagat cgattgtttc
     4021 ctggtgaaac tgtgatcacg tatggttttg gtcatttagt cgaattagat tcgcccgata
     4081 tgtacgatga aaattggaaa caatggtcat tagaacattt gcctattttc cctacacatt
     4141 atcactatca tgttcctaaa gataagaaaa agcaattcaa ggtggtgaaa cagcaacttc
     4201 aatcggccga caccattatt attgcgacag atagcgatcg tgaaggggaa ctgatcgctt
     4261 ggacgatcat tcaacaagta ggcgccgatc aaggaaaaac ctttaaaaga ctttggatca
     4321 actccttaga aaaagaagcc atttatcagg gattccagca gttacgagac gcaaaagaga
     4381 cctatccaaa atttgaagaa gcacaagcac gtcagatcgc cgattggtta attgggatga
     4441 acggtagccc actgtatagt ttactcttgc agcaaaaagg cataccagga agcttttcct
     4501 taggcagagt ccaaacccca acgctttaca tgatttatca attgcaggaa aagattagaa
     4561 atttcaagaa agaaccttat tttgaaggaa aatccgaagt aatcgctcaa aatggcgcat
     4621 ttgatgcgaa gcttgatccg aatgaaaccc aagcgacgca agaagcattt gaagattatt
     4681 taaaagaaaa gggggttcaa ttgggaaaac agccaggcat gattcgccaa gttgaaaccg
     4741 agaaaaaaag cgcggcaagt ccacgtcttt tttctctatc cagccttcag tctaaaatga
     4801 atcagctcat gaaagctagt gccaaagaca ctttggaagc catgcaaggc ttgtatgaag
     4861 ggaaatatct aagctatccg cgaacggata ccccttacat tacggaaggg gaatatgcgt
     4921 atctgttgga tcacttagac gaatacaagc attttttgag ggctgaagaa atttcgactc
     4981 ctattcatac accgaatagt aggtacgtga acaacaagaa agtccaggaa cattacgcaa
     5041 tcattcctac aaaaacagtt atgacagaag cgacgtatga aagtctgaca cctttacaac
     5101 aagcgattta cgagcaagtt ttaaaaacga cagtggcgat gtttgcggaa aaatatacct
     5161 atgaagaaac aacgatcttg acgcaagtcc agcagcttca gttaaaggca atcggaaaag
     5221 taccgataga tctaggttgg aagaagttat ttggcaaaga gagcgacgga aaagagaagg
     5281 aagaagagcc gctacttcct aaagtgacaa aaggagaaat ggtgacggta gatctacaag
     5341 tccttgaaaa agaaaccaag ccaccacaac cttataccga aggtacgttg atcactgcga
     5401 tgaaaacagc tgggaaaacc gtggatagtg aagaagcgca atccatattg aaagaagtgg
     5461 aaggaatcgg tacagaagcg acacgggcga atattattga aaccttgaaa caaaaggaat
     5521 atatcaaggt agagaaaaat aagcttgtgg tgacgaataa aggggttttg ctttgccaag
     5581 ctgtggaaaa agagccgctg cttacgagtg ccgaaatgac cgccaaatgg gaaagctact
     5641 tgttaaagat tggagaacga aaaggaacac aaaccacttt tctagccaat atccaaaagt
     5701 ttgtctctca cttattggaa gtcgtcccag gacaaatcca atccattgat tttggatcga
     5761 cgttacaaga agtgaaagca gccagtgaaa agcaagaagc cgcgcgtcat ttaggaattt
     5821 gtccaaaatg ccaggaacaa gaagtcttac tctatcaaaa ggtggcagct tgtacgtctg
     5881 aagcctgtga ttttaaatta tggacaacga ttgccaaaaa gaaactcaca gcgacacagc
     5941 tgaaggagat tattcaaaat agccgaacaa gccaaccagt gaaagggtta aaaggtcaga
     6001 agggttcgtt tgaagcaacg attgttttaa aagaagactt cactacaggc tttgaatttt
     6061 ctgaaaagaa aaaaacgaac ttcaagaaaa gaacacgacg cacgacaaaa taatggaggg
     6121 ttaatcttat gcgtaataca acacacaaac aacaagaaat cgaaaatcaa aaagccaaaa
     6181 ttcgttcaga acaagagaaa ttacgtgcca gtaaaagaag acttcagcaa ttaaagaacc
     6241 agcaacggat tcaaaaagaa atcgaattag atcgatagac attaaccttg ttacaaatac
     6301 actatcatga tatatttaat gtagtgtatt tgtaacaaaa ggggggaagt aaatgcaaga
     6361 gaaactgaaa gaattgttgg ctattcgcga tggaaattta tctatgaagg aagccagaaa
     6421 attaggaatc gcagcaacca ctgtacaaag attggtgaat caaggaaaat tgatcaaagt
     6481 tgatcgtggt tattatgtag aggatggtca tggaatagat gatttatttt ggcttcagca
     6541 acgtttttcc aggggaatct tctctcatga aacgacttta gatatttacc agctttctac
     6601 gaatatgccg aaattcattc acttaacttt tccccatgga tataacgttg atcgttcaat
     6661 tacaaaagag cagcagttac aatttcattt cgtgaagaaa gaagtttatg aactaggaaa
     6721 agtagaggga acttcctttc aaggaaatcc tattactatg tatgataaag agcgtacact
     6781 ttgtgatatt tggaatccga gatatgaaat tgaatatgaa atgaaattag aagcattaaa
     6841 agagtacatg gaagacccat tgagagatcc aagtaaatta agagattaca tgacaaaact
     6901 acatgtagaa aaagaaatga aataccacat gcaaagctta tattgatgga ggaaaaagat
     6961 gacaccgaca caatttgcag caaaaacaag aaatttagca aagaggacag gattaaatgc
     7021 acagttagta caacggcatt ttatgatgga tcgtttaatt gaacaaattt ctgaatctaa
     7081 gtataaaaat gatttcattt tgaaaggtgg ctttttatta ggatcaaaat atggaatcga
     7141 tagaaggacg acaattgata tcgacacgac atttagaaat agcaaattaa ctgaagaaaa
     7201 attgaagagt atttttaatg atttaactag gaaacccacg aaagaaggta ttgttttctc
     7261 tattcaagga atgaaggaaa caagagaagc cgatttttat cctggatttc aaattaaatt
     7321 ggtggctaat ttagagaaag tacgtgtgcc atttaaaatg gacgtgacaa caggagattc
     7381 tatttatcct gaagtagata cacactatca ccaattaatg tttgaagata aaaaggtgga
     7441 gattccagct tatccaacag cacaaattat tgcagaaaag ctaagtgcta cgttcagctt
     7501 tggcacagat aattcgagag caaaagatta ctacgactta tttaccattc cgaaactaga
     7561 aaatatcgat acgaaagagt tatacaaaag tgttcgaaat acatttacaa aacgtgggga
     7621 tacaaaaccg ttgtcctttt attatgaaag agaaatggat aagatcatag gaaatgacta
     7681 tttggaaaag cagtgggaaa aatatcgctc agttaacacg tttgcgaatt ccatttcatt
     7741 tacagataca gtcaacgaaa ttgatcacct aatgaaaagt gtgatcaaaa ttgaaaatca
     7801 agaaagaaaa cggcagttta aaagatcaca acaaatgaat caagaaatgg agagataaag
     7861 atgatcaata atgtaacttt agtaggacgc ttaaccaaag atccagattt acgttatacc
     7921 gcgagtggta ctgcagtagc gacttttacc ctagctgtca accgaaattt cacgaatcaa
     7981 aacggcaatc gagaagctga ttttattaac tgtgtgattt ggcgcaaacc agcagaaaca
     8041 atggtgacat tagctaaaaa aggtagcttg attggtgtag ttgggcggat tcaaacgcgg
     8101 acttatgaca accagcaagg acaacgtgtg tatgtgacag aagttgtggc cgataatttc
     8161 caactattag aaagcaaagc agcgacagaa agccgtgcgc acgctgatca atcgtccacc
     8221 agtccaagca ccaccacttt tgaacaacgg gatacagcga cgcctaataa caatggattg
     8281 aacgctttac agaatccatt tgggaatcca tttggtggac aatcaatcga tattagcgat
     8341 gatgatctac cgttctaagt agcattttct attggttgca tttgctacgg tttatgttat
     8401 aatttagtca acaaaaagaa ttttcaatct ataaccaaaa accactagct ggcgggctag
     8461 tggttttctt ttacgtttct attataagaa ttaacgggta ggcttactgt ctttcttggc
     8521 aaatttacaa tcaagccatt tgcagatata gtgcgcggct acttctgcca tgattgcaaa
     8581 aacaaaatca aaaagaattt tcaaacctat aacctcctcc ccttgccaga ttaggccggg
     8641 gtagcagaca gcaagactat tatagcataa ttgaaatatc caaatgattg gatttttgct
     8701 ataattttag cgaggtgatt gtgatgaaca aatatgttgg tttgcttgat aaaatccgag
     8761 taataaaaac gcaaccgtta ttggttcgct ttactttaca aacgattcat gaatcgatta
     8821 attgtgtagt tgcagatatt gaaattatcg ataaattgct aattatggat gatggaaaat
     8881 acaatattgc cgtcacaggt cacttcaata aacgaaatca gctagttatt gctagcatgt
     8941 atgttagaaa tcccgatcat tttacgcgat cgatgggcat ataaaaaaag aagagttgca
     9001 atcctaatgt aggactgcag ctctttttgt tttacataga aacaagaaaa atgaaaaggc
     9061 ctttttagga aggcgcgagc gccttctcaa ttgaaaaacc tctctcactc caaccgccac
     9121 cgccgttcga gaagaaagga agtgaacgtt gcacgttcac taagataaag ggtcttgcaa
     9181 agcaagacaa aatagaaaaa acttcctctc accaaaaggt tcgttcctgt tcgttatctc
     9241 tttattgatt tgccagaccg gcaacaagtt gccttttatc accaaaaagc gacaaggaca
     9301 agggtaaatg gcacgctgcg cgcccttgtc cttgtcgctt ttcgttgatt cattctggcc
     9361 aacaaatcaa taaagaaaga actaacgaaa ggaagtaaaa cctttcctaa gaggaggcag
     9421 aatcaatcat gcgaaagaaa tttgattatt ggggtgttcc cttcagcgaa ttattcccaa
     9481 actatcatgc accacatact gtcgaatgcg attgtggaca aagagcgaaa tgtatcaaaa
     9541 gctatcgttt gtatcaatgt ccaacatgcg gaaaaaaata caccttgtct tatggcgatt
     9601 atattttgat tgatgagaaa ggaaagaaac gctgatgaaa acataacata aattattgac
     9661 tgtaaaagaa gtcgttcaaa ttttggtgga caaagaagtc atttctgaaa aagtagcaga
     9721 agctttactt attccgcggt actggacgat agaaacccct ttagtagagg atgcaccgac
     9781 tatgctattt gaagacctag tgaagattgc aggatatgaa ctgcattatc aagaaaacat
     9841 ggaaacttat gaaaacgaat attggttaac caaattagag aactaaaaag gagaaaaaaa
     9901 tatggctcaa aattactatg acgaatttgt caaattacct ttggataaaa tggcacaaaa
     9961 aatggaggat atgacattcc tataccatga gacacgtgtt ccaaaaaaac attataagga
    10021 aagattgtcg gtagctgtgg aagaaatgat tgaatcaggt gtcgaaatga atctcattgc
    10081 gacgtactat cgaacactgg aagaactgaa aaaacaaaat gcaaaatggt ttttccaagc
    10141 cttactatgc ttggaagtag gtgtcaaacc aagcactatt aaaccttctg aatatcaagc
    10201 tttagaacta acgtatggga aatttgtcga aacgaaaaaa gccaagactg tttcaagtga
    10261 atggttagat tattttgaaa atatcaataa gtatggcgcc tattacacca tgaaaaagga
    10321 ggacaacgaa aatgaataag gtgatttatc aactaacaac ggaagatgtg tcacactttt
    10381 taacaaacaa agaacatttg aatgaagtaa tcagacggat tcaaaaagac tttagttgta
    10441 tggaagaaat gaagtacttt attcaaagag tcgaagaaca attgtatttg gaaagtgaaa
    10501 cgagtcaaac gaaggtcaca gtcagcaata attatttaga cgtgtataaa catcgtcctg
    10561 aaacggtaaa aaaaggaacg gagcttctac gactagaaac agaaaaatac atcatgaatg
    10621 tttacctaga aaggagtgaa ctggtcgaaa actttgtcag ctgcacgatt tgcaggaaac
    10681 actattactc agaatcagaa tattattcaa tttttgagag catggaatta atggaagaag
    10741 aaatggaaga gctaaacagc aaaaatgcga cgatagacga ttattatctt gtatttacta
    10801 gatttttgac gtgtggaacg gaatctatcg tgttaatggg aatggattat gaactcgctg
    10861 tacccgaagc atttttgagg gaatatgtag aagaagtaga taacccaggc gacgactggt
    10921 acacgacttt aactgatttt ttagatacct acacttacga cgatacagaa gaaatccaaa
    10981 atgaacttga ccgtaaacga atgccatatc aacgatttga aaggaaaaaa aggcaataat
    11041 catttatacc gaaaagtgag aatgtgtgaa ataagaacaa aaaccttgaa attaagggaa
    11101 tggttcttat ttcgcaccaa tcgctccaac cgcccccgcc gcttaggtgg tgcgaaataa
    11161 gcgggcaaag cccgataacc taagagaaag aaggagatcc atatgaataa aatcattcct
    11221 ctgttgttcg tactgtgtat tggcgagata cttatgcgtc atggtgcagc tgtacattta
    11281 aacttcgtag tattcttagg aatactagta ttttgtttga ttttttggcg ctttgtgtta
    11341 gcccttgtga gtctactatt caagttgatt gcagccatat ttttcatagg gttatttcga
    11401 tgaaaggaga gagtactaat gccaattgca ataggaaata aacggttacc cgtgacatta
    11461 gatgaaaaga gacaaaaaga attgcagcaa ctaaagcaga agtacggaaa aagtgaatct
    11521 aagattatgt gtattgcgtt agatctattg atcgcgcaag aaaaagcagg atttgatata
    11581 ccagcactaa aaaagtgacg tcacttttca tttgaagaaa caaaagtgat agcacttaat
    11641 tgttcctact atttagaata ttttctatgt cctttttatt ccattttgta tcaataacta
    11701 tgaaatcttt aaagtatcca gatcaatttt tttcttacct gattctaaag attttgtttt
    11761 cttaaacata ttatgatttc ctttcgacta ttttcatata aatgttaaca tagtttatgg
    11821 attcatggaa tgttaatcta atttaataga aaaggataat taagtatata cgttttttct
    11881 tatgtatgtt atactatgta tatacagaaa gaggtgtcta ctatggaaat gttacctata
    11941 aaaaaatggg gaaatagtaa tggccttaga ttgccaaagt atattatgga atatcttgga
    12001 attcatacag aagacaaagt gaagataata caagaagaag taaacggtca gaagcggcta
    12061 attatcgaag cggctaatat agaaaatgaa ttaacaattg aacagttatt tgaaaattac
    12121 actgatgaaa gaaatcatgt gacgattcaa aatttaggtg aagcagtagg taatgaaaaa
    12181 tggtgagaaa acctagacaa ggcgatattc tattattgaa tacagcacct cgatctggac
    12241 acgaacagac aggtaaaaga ccttatattg ttttaagtca tgatattatt gcggattata
    12301 gtaacgttgt tacagttgct ccaatttcta gtacaactag aaactatccg ctatatgtaa
    12361 atataaactc agaatatgaa atgaagacaa caggaaaagt attattagat caactaacga
    12421 caattgatta tgaagccaga gagtgtattt ttttggaaaa agcgcatgat agtttagttg
    12481 aggagttatt gatgaaagtt agaacagttt ttcaaaaagt aagcaaataa aatagaaaca
    12541 gcagcatgat caactattcg tgattgacca tgctgtcttt ttttattcta tatacggttt
    12601 gtctcgtaac attgtagtct tttgcaatct tagcgatcgc aacacctttt tttagatcct
    12661 caacgatgtt tttataaaca agacgacgtt ggggatcttt tgcattggca ctgtatagct
    12721 taggacgtcc tttataaaca ccgttcgctt ttgcaatctt aatgccttgt gcctgacgtc
    12781 gtttagattc ggtacgttct tgttcagcga tcatggccaa aatttgaatg atcaaatctt
    12841 taatgaattt atccaggaga ggattgccaa ttgcttcggc catgatcggt agacttgtga
    12901 tgatcagctg cacatttttc ttcttcaagt aattgactga agcgatgatc tcgtcgtaat
    12961 ttcttccaag tcgatcaata gcttccacaa taaaaatatc ttgatctcgg acgaaatcca
    13021 gtgcttcttg aaaaacaggt cgatgagtaa tcgttgcgcc agattgtttc tcaatgaaaa
    13081 ttctctctgc accgaatttt ttcatttctt caatctgccg ttgttcattt tgatcgatgg
    13141 atgagacacg tatgtatgca actctcaaaa tttttaccta ctttctgcaa ctatttaaaa
    13201 aacaccctaa tcatacacga gaaaaccaga tttttcaatg tcgcggtcgt gtctagttag
    13261 ggtatacctt atatagacaa aaactaatga tggaggaaat agtatgtgtc acttttcttt
    13321 ttaaatggca atattttttg taaataaatg tcaatcaaga aaatttaaac gattatgaca
    13381 ttaaaaatat attttatgaa ttttctagta tataacttga tttatctgtt aagatttatt
    13441 aagaaaacgt tttcttattt ttgatttcga ggtgatagac aatgaaaaat aagtttattt
    13501 tatctttagg tattttaact attggaatta gtgtaactgg aactacaatt cctacatttg
    13561 ctgatagtac aaatgaacca actactgtag tagataataa ccaagaatta actcctttag
    13621 ataggaacgg aatagccatt ggtaacccaa ctaacgactt aactgttact gaaaattatt
    13681 taatagtttc tccattactt gctcgagcag cttctaaaac gatacgagtg acaggaacga
    13741 tgatttttga taaagttggt tggccttcta gacctcctca atcacggaat tggaaagaaa
    13801 aaagaaatgg ttattggtac tatggaaaat tgtatttaca aagttataaa tcagctggaa
    13861 acaattggat tgcgacttat tcaggaacct taactagaaa gtagggattt tttatgccag
    13921 aatttgtgaa cacaccaaat ttttatcaag atagcgatat tctaagtaaa attaatttac
    13981 cgaaagaaga atcagcttta caagttcagc gaactttaca ggagacacaa aaaattcaaa
    14041 aatcaatttc taatctagaa gattctgaag aaaaaagaaa aaaaagagac caaaaaacat
    14101 atcaaaaaga aaaataatga ttttaaaaaa agagtgtcta gtcgacattc tttttttcta
    14161 attgaaagtg ttcataaaat cacccatttc tggacacttt ctttttttgc tttatttttc
    14221 aaaaaaacaa ttcatttcat gttcataaac ccataacaat atctatgttc agttaaacta
    14281 tatggataaa gttatgttac aataaaatta atgaaggagt gatttttttg aaaataggat
    14341 acgcccgggt atctactggt ttacaaaatt tggatttaca agaagacagc ctaaataaat
    14401 ttggttgtga aaaaattttt actgatcata tgagtggggc aaaaagtaat cgaccaggat
    14461 tagaaatggc cattgatttt gttcgctctg gcgatacact tgtcgtttgg cgcttagatc
    14521 gtttaggtag aaatatggaa gatttgattt caatcgtcaa tcgactgaat gagcgtggtg
    14581 tgagttttca tagtattcaa gaaaatatta cgatggacaa atcaagttct acaggacagc
    14641 tcatgtttca tttgtttgcg gcatttgcag aatttgagcg taatttgatc ctggaacgat
    14701 ccgcagcagg acgagcagct gctcgtgcaa gaggacggtt tggtggtcgt cctgaaaaat
    14761 tgtctgaaca agatttggaa ttactgaaga ctttagtgga tagcggtaca cctattaaga
    14821 ctattgcgga acggtggaac gtctcaagaa ccaccattta tcgttatttg gcaaaaatgg
    14881 aggagaaaaa tggaaagaca aattctcatt agtttttgtc atttaatgct gaaaattttt
    14941 gccatttatc tagaaaagtg acaatagtat gagaattttt tgtaagtgtc tactgataac
    15001 ttattctcaa atgttgtaag gattttattc atttgttaat attaaagaac ggaactccaa
    15061 aaaagtccgt actctaattt gcagtctctc actcttttag agtgagagtt tttattagat
    15121 tttcaaatta attagtaaa
//
LOCUS       DAZUJR010000071        15068 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.071, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000071 DAZUJR010000000
VERSION     DAZUJR010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15068
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.071"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            416..2155
                     /gene="yfcC"
                     /locus_tag="ACG804_002144"
     CDS             416..2155
                     /gene="yfcC"
                     /locus_tag="ACG804_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HFS4833065.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            2312..3496
                     /gene="iadA"
                     /locus_tag="ACG804_002145"
     CDS             2312..3496
                     /gene="iadA"
                     /locus_tag="ACG804_002145"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008798 - beta-aspartyl-peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HFS4833066.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            3607..3810
                     /locus_tag="ACG804_002146"
     CDS             3607..3810
                     /locus_tag="ACG804_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HFS4833067.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(3911..4573)
                     /locus_tag="ACG804_002147"
     CDS             complement(3911..4573)
                     /locus_tag="ACG804_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4833068.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(4586..6088)
                     /locus_tag="ACG804_002148"
     CDS             complement(4586..6088)
                     /locus_tag="ACG804_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4833069.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            6636..8315
                     /locus_tag="ACG804_002149"
     CDS             6636..8315
                     /locus_tag="ACG804_002149"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HFS4833070.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            8442..8921
                     /locus_tag="ACG804_002150"
     CDS             8442..8921
                     /locus_tag="ACG804_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HFS4833071.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            9140..9820
                     /locus_tag="ACG804_002151"
     CDS             9140..9820
                     /locus_tag="ACG804_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HFS4833072.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            9828..11159
                     /locus_tag="ACG804_002152"
     CDS             9828..11159
                     /locus_tag="ACG804_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DRTGG domain-containing protein"
                     /protein_id="HFS4833073.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            11174..12136
                     /locus_tag="ACG804_002153"
     CDS             11174..12136
                     /locus_tag="ACG804_002153"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HFS4833074.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            12247..12585
                     /locus_tag="ACG804_002154"
     CDS             12247..12585
                     /locus_tag="ACG804_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HFS4833075.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            12664..13371
                     /locus_tag="ACG804_002155"
     CDS             12664..13371
                     /locus_tag="ACG804_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HFS4833076.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(13474..14955)
                     /locus_tag="ACG804_002156"
     CDS             complement(13474..14955)
                     /locus_tag="ACG804_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4833077.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLIKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
BASE COUNT         4834 a         2571 c         3206 g         4457 t
ORIGIN      
        1 tcattattgc aatgaagttt acctgatata acaaaattgt ccaacaggat acctttttct
       61 aatagaaata aaatacacaa aaattgaagg atagataatg gatatttata agtgtttatt
      121 attttttttg caatgaaatt caatttttca atgattgtaa aatgaaaaaa acaggacgag
      181 attttctcta atctaaaaat aaaaaaagaa ttttaaggaa aaacagagaa ataaaatact
      241 taatataaat ggaaagagaa aaaaataatc atacatagga gaaaaaaaac aaaatagaaa
      301 aaagtgattt tctaataaat tattcatgtg gaaatgtcat ttttactgta taattcattt
      361 gattatccat tttttattca tcaaaattac tgaaaaaaga aaggaagaaa taaatttgaa
      421 gaaaacaaat tcttcaggaa aaccgaaacg cgacttcact aaattatcga caccccatac
      481 gtatgtcatt atttttggtg tagtcatctt tgcatggata ctgacttttg tcgttccagc
      541 aggaaagttc agcacgcaag atattgaata caaagatgca aatggcgaaa caagtactcg
      601 tactgtttta cgtcaagatt ccttccgtta tgcttacgag ctggataagt cgtatgtgtt
      661 tgatcaatta gaagaactgc aagatcatcc agcagaacgt gaaaaactgg atgttccgga
      721 aaaaggattg gaaaaagtca ttgctgacgg agaaaaaaat cttacgcagg aaaaactaga
      781 tgaaatctcc ttgacagatg atgtgcttta cgatcagtac ggcgaaaata tctatgatac
      841 ttctaaaaaa ttgcataaaa cagccaaaat atggggaaca gatgattttg gcggctttgg
      901 tttcttaaat tttgtttttg aaggactagt atctggagat aagtatggat ctgctgtagg
      961 gatcgctgca ttgatccttg ttgttggagg tgcttttggt attattatgc gtaccggagc
     1021 gatcgacgca ggtatctatg cgtttatcag taaaactaag ggactggagc gtttagcttt
     1081 accgctatta ttctttgctt tttcattcgg tggcgctaca ttcgggatgg cagaagaggt
     1141 aattccattc tcaatggtga tggttccatt tgtcattgcg ttaggatatg actcgatcgt
     1201 agcagtaacc gtgacttatg tcgcatctca agtcggaaat gcgacctctt ggatgagccc
     1261 gtttagcgta gcggtggctc aagggattgc tggaatcccc gtgttgtctg gtgcgacatt
     1321 ccgattgatt atgtgggtag ttgttactgc attagccgct ggttatatga tgatatatgc
     1381 agaaaaaatc cgtaaaaaac cagaaagttc gttgacttac aaatcagatg attatttccg
     1441 ttctcatatc aaaaagacat ctgatgaaaa taaaaaattc atgcttgggc ataaattgat
     1501 cttattagag atgttagttg tccttgtctg gatcgtttgg ggcgtgactc aaaaaggcta
     1561 ttacattcca gaaatcgctt ctcaattctt tgtgatggga ttagttgctg gaatcattgc
     1621 tgttcttttc aaattagatg gaatgaaagt caatgacatc gcttcttctt tccaatctgg
     1681 tgcagctgat ttagctggta cagcaatcgt agtaggtatg gccaaaggga ttcttcttgt
     1741 cttgggagga tctgatgcat ctgttccttc agctttgaat acgattttgc atgggatcgg
     1801 gacggcgttg accggtgttc cagctgtcat tggtgcttgg gcgatgtaca tcttccaaag
     1861 tttgttcaac ttggttgtta catcaaattc aggacaagca gctttgacta tgccaatcat
     1921 ggctccactg gcagatttag taggtgtatc cagacaagta gcagttcttg cttatcagct
     1981 tggttcaggt tttatggacg cttttacacc cgtatcagcc agcttgattg gtgtgctagg
     2041 tgttgcacgg atcgaatggg caaaatgggc aagattccaa atcaagatgc aaggattcct
     2101 gtttgtttta ggaactattt tcatcatgat tgccattgca ataggtctgc agtagtactg
     2161 gagacctgta aataaaaaag taatccaaac agtagataag gactccaaga accgtcattt
     2221 tacggtaaaa tcaaaggagt aaagatccta tcgtttggat tattttttaa gatcctatca
     2281 tcagttatac ttaaagaaag aggaaaaatg tatgaaaatc attcgacaaa ttgaagtgtt
     2341 tgcaccagat tacttaggaa aaatggatgt actgattgcc ggtgggaaga ttttggctgt
     2401 agaagaacag ctagaaggcg gctacgaagg agtggaagta gaagaacttt caggtgaggg
     2461 aaaagtacta accccgggtt tcattgactg tcatttccat attttaggtg gaggaggaga
     2521 aggcggttat caaaatcgaa cgccagaagt cacattgagc caattgacta cagctggtgt
     2581 aacgacagtt gtcggttgtt tgggaacaga cggagaaggt agagatatga ctgcgttgat
     2641 cagcaaagcg aaaggtctgg aagcagaagg aatctccact tatgtatacg aaggttcgta
     2701 ccgattgccg gtaaaaacag taacagattc tatcatcaaa gactttttga caattgataa
     2761 aattatcgga atcggagaaa tcgcagtatc cgatcaccgt tcttctcagc caagttttga
     2821 agagttcgct cgtgcagtag cagatgctcg tgtaggaggc atgttatccg gaaaagctgg
     2881 gatcatcaat gtccacttag gcggaggaaa aagaaagcta gagctattga cacgaatcgt
     2941 agaagaaaca gaaattccga tcacacaatt tttgcctact catgcaaatc gcacaccaga
     3001 attatttgaa gcttgcgtgg catttgccaa acgtggtggc acgattgact tcactgctag
     3061 cgaagatcct gatttttggg agaagacaga tggtgaagtt cgcttcagca aagcactgaa
     3121 acgattgatc gaggaagatg tttctttaga taatttcacg atgacctcag atggacaagg
     3181 aagcttgcct tattttgatg aaaacaatca tttcctaggg ttaggagtag gaagtgccaa
     3241 ggcattgcta gtagggatca aagaagctgt gcaaaaagaa agtatccctt tggaaatcgc
     3301 cttacgagct ataaccagta atccagcacg tatattgaaa ttggataaaa aaggaaaaat
     3361 cgaaattggt gctgatgcag atctgtgtat cttggataaa gaaacgcttg atattgatac
     3421 agttatcgct aaaggagaaa taatggtcca agaaaaagaa gtcaaagtat gggggacttt
     3481 cgaaaaaagt ttttaatcaa cagctctaac tatctttttt agaaaacgag cgttctgttt
     3541 gtctgtatct gttgttgatg ttaccctgaa ggtagatcaa taaacaaact aagaggagga
     3601 agcacaatgg cagatttaaa aggacgttct aaagatatga aagataaagt agtcggtgaa
     3661 ggaaaagaag catacggcaa agcaacagac gacaagagca aagaaacaga agggaaagca
     3721 caatcactag gtgctgacat caaagaaaaa gctcgaaatt taggcgacga agtcaaagac
     3781 aagttttctc gaaaagacga aaaaaaataa aaaccactta ttactaattg aatcaagcaa
     3841 ataaaaaatc cgaaccatat ctgcgagaca gatatggttc ggatttttta tttgatcatt
     3901 atcctgtttt ttaaacttcg attttttgaa attttttatt ttttagttca aagacttcat
     3961 cacagctttt tgctacttca atctcatgag tcacgatgat aatacagcga ttttgttcat
     4021 gggcgatttc ttggaaaagt ttgacgatat cttgtgaagt tgtttcatct agatttccag
     4081 taggctcatc cgctacgatt agttgatgtt cacagcagat agcacgaacg atagcgactc
     4141 gctgctgctg acctcccgaa agtttggtca cctgtttttt tgctaatatt tcatcaattc
     4201 ctacacgagc cagtcgatct aaagcaactt gtcgataatt ctcttgcttg gtcttagtga
     4261 tttccattgc tgctatgacg ttgtctagag ccgataaata aggaagcaag ttgtaagctt
     4321 ggaaaataat cgagacatca tttttacgat aacttcttaa cccgattttg ttcagtgaac
     4381 gatcttgata gtataccttt ccttcttttg gtgcatctag tccagaaata agcgaaagaa
     4441 aagtcgtttt tccagaacca cttgctccta aaatagcgta catttttcca gcttcgaaat
     4501 tcagttctac atctttataa agcgcatctt gcggatcttg ataccaaaat cccaattgtt
     4561 ctgtccgtaa catcaaattc ctcctttagt ttaataggat ttttcttggg tttaatctta
     4621 atatccctat agaagctaaa aagacagaaa acagactgat tccaaatgct actccggcta
     4681 atagtcccaa ttgtgcaggt ttgacattga tttccaattc gctgacttga tcagaaacag
     4741 caaatggatt attcgtggtt ccttgttgac catcgcgttg accgccttgt tcttgtctgt
     4801 tacctggcat ttgtccaccg ccaggagctt gctggttttg tgtcgtggtt tctgtctgtt
     4861 ggtcaagtag ctgctgtccc acggcattcg cgacgacgtt tccgctaagc gaagcaactc
     4921 ctaatgcaag aatcatacaa atagccactt cggtaaacaa ttggagaatg attttacttc
     4981 tggattctcc taaagatagc aagacgccta actcatgccg acgctcccga atggtaatca
     5041 taatgatcag agtaagtatg ataataccgg ctacagccac tagtaaaaca acatttttag
     5101 aaaaacttgc cacgttgttt aaaggttcca acattgactg atacatggaa tcatttgatt
     5161 gtaagctaaa tgtatctgtg tcgatcagct tctcagcttc tttgagaaac tcatccattt
     5221 tatctggatc agatagagtg taaatagcag aatctatcgt gttatcgtca gatgtcccat
     5281 ttagttcatt tgcaaaagtg taagaagtgt aaagtgtatt cgacggattc atgaagttga
     5341 atttcatacc catactgccg cttgtttcgc tggattcata aattcctttg atcgtcattt
     5401 cataagtggt atcttcatct tcagtactcg tgattgtgaa agtatctccg actgccaggt
     5461 catttgtttc tgctagagta gaatcaatga ctacattgtt tgtgcctttg tcgctgtcat
     5521 ctattccttc accatccgtg atttttgctg ttccatcaga aaaattacta ttttgtgcag
     5581 ttgctgacac accactgatt tgaaagtctg cttgagtcat ttgcggattc ccgcccattc
     5641 ctccagcagg ttcaccgcct gcatcagtag tttctgaact gtcttcactt gaatcagaac
     5701 tagtgatggc agttattcca tcttttgcca tagctgaggc ggaactttca aaggaataac
     5761 tctttacatt atctaattca gctatttttt ccgcgtccgt taaggaaact ggtgtaagag
     5821 aaaaactgcc tggatctgga cgttcttcag tggtagaacc gcttgaagaa gtttgttcct
     5881 gttttttaaa tgaagcttct cgattggcac ttaaagtcac tgttgctcca acttcttttt
     5941 gtgcttgatt cgctgcttct tctgcagcgc ttcgaatcgt gaggccagct agcacaaaaa
     6001 taagaatggc tgtgaacacg gcaaacaata acaatgaacg tccccatttt acttttgtac
     6061 ttttccatgc acgtttcata aaattcatat tttgcatccc tcctagtaga tgcatttgat
     6121 aatagacaac ctatcttaaa gctagcttaa atcttatgct gtttgcacac catcaacatg
     6181 aggttctgta tatataaaaa gtcactatag ttattgcaaa aaatgtggta aaatgaaaaa
     6241 agtatgtttc aaaccgacga agaagaaatg aaagaggaat agcaaaagaa atcctagatg
     6301 ctacagaggg atttttacgt gcatagttgt tctaacaatt gctgatacta gcgatttagt
     6361 ttatttgttg tataataatg gggaacagct gaatacttat ataagtattc tggctatagc
     6421 gtttcgcaaa agatccattt tgttaatgaa gtatatccaa aataaaatgc ccatccaact
     6481 gtcagaacgc ggatgtgctg gtaattttcc tgctgattct ccataagttg agaaatagtg
     6541 attttgcata tgcttcattg gaatggctca tatatttaga taaagaagaa aatcgacatc
     6601 tttaaacttg gatgtcataa gaagaggtga agtttgtgag taccattaaa attatcccat
     6661 taggcggcgt tcgtgaaaat ggaaaaaaca tgtatgtcgc agaagtgggc gaggatattt
     6721 ttattttaga ttgtgggcta aaatatcctg aaaatgagtt gttggggatc gacgtcgtaa
     6781 tccctgattt tacgtattta gaagaaaaca ttgatcgtgt agctggtgtc tttttaacac
     6841 atggacatgc agatgcgatc ggggcacttc cttacttgtt gtcaaaaatt tctgtaccag
     6901 tattcgggac agagttgacg atcgagttag caaaattgaa tgtcagtcgt aatgaagcag
     6961 ccaaaggatt taaggatttc catgtggtag atgagcatac agaaatagac tttggtgaaa
     7021 cagtagtgag ctttttccgt accactcata cgataccaga ttcagtgggg atcaatctga
     7081 aaacaaaaga aggtagtatc gtttatacgg gagattttaa atttgaccaa acggctatcc
     7141 caatgtatca aacagattat gcacgattgg cggaaatcgg caaagaagga gtcttagcct
     7201 tactaagtga atcggcaaat gcagaaaatc ctcagcctgt agcttctgaa gcccaaatag
     7261 cagatgaagt atttgatacg atcaaatatt gggaagggcg tatcatcgtc gcttgtgtag
     7321 caagtaattt gcaacgagtg caacaagtat tggatgcagc agaaaaagca caacgaaaag
     7381 ttgtcttgac tggtcaagat ttcgaacgaa ttattcgcac agcgatgcgt ttagaaaaac
     7441 ttcaattacc aagtgaagat ctgcttgtta cgttgaaaga catgaaaaac tatgatccag
     7501 aagaactgat cattttagaa actggccgaa tgggtgaacc catcaagtct ctgcaaaaaa
     7561 tggcaaacgg tacacaccgt aatgtcaaga ttgaagaagg agatttggtt tatatcacta
     7621 ctacgccaag catcgcgatg gaaaccatcg tggcgaaaac ggaagatatc atttatcgag
     7681 ctggtggaac agtgaagttg atctctgaga atatgcgcgt ttctggccat gccaatccta
     7741 atgacttgca attaatgatc aatttgatga aaccaacata ttttgtgcca gttcaaggag
     7801 agtatcgtga attagctgct catgcagatt tggctcatgc agtagggatg ccatacaaaa
     7861 atatctatat tactggacgc ggagacgtgc tggaatataa gaacaagcgt atgagtgttg
     7921 caggaactac aagtgcagaa aatgtaatga ttgatggatt aggcataggt gatatcggaa
     7981 acattgtttt acgtgatcga aaaatcttgt cagaagacgg gattttcgta gcggttgtca
     8041 ctatcagtcg gcgagaaaag aaaatcattt caaaacctca aattacttca cggggattcg
     8101 tttacgtaaa agctagccgt gatctgatga aagaaagcag caatatgatt gaaacaatcg
     8161 ttgagaaaca tttagaaagc aatgattttg agtggagcaa attaaagcaa gacatccgag
     8221 atcaattagg ccgttactta tttgaacaaa caaaacgccg cccagtgatc ttgccagtca
     8281 ttatggaagc tactcaacgt cgaaataaaa aataaacaaa aagagtaaga tgaacctctc
     8341 tatagagtgc tcgtcttgct ctttttttgc gaaaaacaaa taatttttga atacagcatc
     8401 cctcgcttta taataaacga tagaataaag ggagtgaatc aatgatgagt caaacaaaag
     8461 tcgaacgtta tttagaagaa caaaagatca gctatcaacc acttgatttt agtcatgtgg
     8521 tagaagaatc tttcacagaa gaactacaaa aaagagggat tgatccagct ttgatatgta
     8581 aaactctcgt agtgaaagga aacaaaactg gggtgatcat cgcattgatt cctttgaacg
     8641 atcacttaga ttacaaaaaa acgagacaag tgacgaaaga tcgtaaagtt ggttttcctg
     8701 gaatggattt tgtattaatg catacaggat atccccacgg agcaaacacc cctattggaa
     8761 taaaactcgc acatcctgat tattgttttt tagcagacag ttctttaaaa gaaaaagaag
     8821 aagtaattgt gtcaagcggt gaaatcggga gaagccttcg gataaaagta gccgatttag
     8881 aaaagatcgt ccatcctatt tacgctgatt taattagtta agggacgaga agagaagcta
     8941 agcagagcag agacctcaaa cttgagatta tatctgcttg gtacttggtg catcctgtat
     9001 tatctgttac aattgctttg tacatactgt actatcaatc caatgaaaat atatttagca
     9061 gctatatttt ttcattgatg tgcaagtgat gaaatcgttt ttaataaaaa agatacagag
     9121 aaaacgcgag gtgtaaaata tgaaaattac gtatcatgga cattcctgtt taacaattga
     9181 aatggaaaat ggccaacgcg tgatgattga cccgtttatt acaggaaatc cattgacaga
     9241 cttaactgca gaagaagtaa agacagattg gttgctgatt actcatggtc atagtgacca
     9301 cataggagat atgattccta ttgcaaaaga aaatcaagcc acaattatca gtattgttga
     9361 gattgctgat tatgcgaaca gcagaggagt agattcattc ggtatgaata tcggtggaaa
     9421 acatgcgttt ccattcggcg tggtaaaatt cgtacatgca cagcatagtt caagctatga
     9481 agtagacggt atcgttcagt atatgggcga gcctagcgga attattattc aagcagaagg
     9541 aaaaacgatt tatcatgcag gggatactgc ttatttcagt gatctaggat tgcttgcaga
     9601 agaattcgat attgatgtcg ctttcttgcc gattggcgat aactatacga tggggccaga
     9661 agatgcagca aaggctgcgc aaacaattcg tgccaagaaa gtagttccaa tccattacaa
     9721 tactttccct gtcattgaac aagatcccga atcttttgta gagttactgg aagatagtga
     9781 aggaaaaata atgagcgtct cggaaacgct ggaagtgtag gcagaaaatg gcgacaaaac
     9841 atgatttgat tttagaatat attgaaagtt tacctgttgg caatcgaatt tctgtaagaa
     9901 gcatcgcaaa agaattgaat gtcagtgaag gaacagcgta ccgtgcaatc aaagatgcag
     9961 aaaatgtcgg actagtttca acaattcaac gagtagggac catccgtatc gaacgcaaat
    10021 taaaaaaaca tattgaacgt ttgacatttg gcgaggtcgt caggatcatt gaaggggacg
    10081 ttttaggcgg ggcggcagga ttagacaagg tcttgaataa attcgtcatc ggcgcgatga
    10141 ctaaacatgc catggaacgc tatattacgc caggatcact aatgatcgtc ggcaaccggg
    10201 cggaagtcca aaaattagca ttggaagatg gcgccgcagt attgatcaca ggaggattca
    10261 atacgactgc tgagattgca aagctagctg atgatcttga aatgccgatc ttacgcacct
    10321 cttatgatac atttacagtc gcaaccatga tcaaccgagc gttaagcgac caattgatca
    10381 aaaaagatat catgcttgtc agtgatatct atatgccagc tgaaaagact cattatttgc
    10441 agcagacaga tacgatttct gattatcagc gtttgtcaga agaaacgcag cattcgcgtt
    10501 ttccagtcgt caaccgccat catcgtttga tggggattgt tacggcaaaa gatgttttag
    10561 ggaaatcgcc aaaccagatc atcgatcggg tgatgacgaa agaaccaatc agtgtaaaga
    10621 aaacaatgag tattgcctct gttagccatc aaatgatctg ggatgggcta gaagtcatgc
    10681 cggtcgtttc cgatgacttg acattggaag gcttgattac ccggcaagat gtaatgaaag
    10741 cgatgcagct tgtccagcga caaccgcaga ttgcagatac gatttcggat cagatatctg
    10801 gaaatatcca tacgattgat actgaccgtg aaggaaatcg tttggaaaac cctaagttca
    10861 aattcgtagt agcaccacaa atggtcaatg gcgttggaac catttctttt ggcgtactta
    10921 gcgaaatcat ttctgatgtc gcacaaaaaa caatggtgat gaaccaaaaa cgaaatatct
    10981 tgattgaaca agtgaaccta cattatttgc ggctgatcca attggaaagc gaattagaca
    11041 ttcgtccacg tgtattggaa atcggcagac gttccgctaa actggatatc gaagtgttta
    11101 ttgaaaacac catcgtttcc aaagcaatcg ttgtttgtca agtaatggaa cgttcttaga
    11161 aagcaggagt gaaatgacag tacagcaaga aatagtagat acaataaaaa aatacgataa
    11221 aatcattatc cacaggcatt tgcgccctga tcctgatgca ttaggatcac aagtaggatt
    11281 agccgaacta ttacgggaaa gtttcccaga aaaagaaata cgtcaagtag gtgaaacgat
    11341 tgaagggctt cgctttttag cagaaatgca agaagttgaa gatgtcttct accaaggagc
    11401 gctagtcatc gtgactgata cagctaattc acccagaatc agtgatcaaa gatatcagtt
    11461 ggcagaaaaa ctgatcaaaa tcgaccatca tcccaatgat gacccttatg gagatcttgt
    11521 gtgggtaaat acaaaagcaa gtagctgtag tgagatgatt gcagaatttg ctttgatgtt
    11581 tcctgaatct ttaaagatga acgttaaggc tgcacggtta ctttatgcag gaatcgtcgg
    11641 agatacaggg cgctttttgt atccctccac gacgtcccgt acattagaga ttgcttcgat
    11701 attgagaaat tatccatttg atgcaagtgc tttgaacaga gagattgaac aaatgccgat
    11761 gaaagtcgct aaactttccg gttatcttta tcaaaatatc caggtggatg aaaatggtgc
    11821 aggaagaata atccttccgc aagaaattct tgataaatat ggaatcgatg attcagagac
    11881 agcttcgatc gtttcacttc ctggagtgat tgacgaagtg ctggcttggg ggatttttgt
    11941 tcagcagcct tcagggtatt accgcgtacg tttacgttct aaggggccga tcatcaatga
    12001 attggctaaa cgccatcatg gaggaggcca tccattagca agtggtgcga atgcaaaaga
    12061 tttagcagaa gtagaggaaa tctataaaga gatccaagat atatgccaat cgtataagag
    12121 cagaaaaaca gaatgatact tcgttcgaaa acgtgccttt tgtagtaaaa atcacaaatg
    12181 tatcttttca agatcttctt tttccgttac aatagtgctc actaaagatt ttaaaggaga
    12241 aagaagatga cattaccaaa ttgcccagaa tgtggctcag agtacacata tgaagatcga
    12301 ggcttgttga tttgcccaga atgcgggaac gaatggaaca aagaagaaca agaaactgtc
    12361 atagaagacg gattagtggt attagatgca aatggaaacc gtctgttaga gggcgatagc
    12421 gtgacagtga ttaaagactt gaaagtaaaa ggtgcgtcag gtgccattaa acaaggaaca
    12481 aaagtcaaga acatccgttt agtagaaggc gatcataata tcgattgcaa ggtagaagga
    12541 tttggaccga tgaaactgaa atcggaattt gtgaaaaaga attaaagaat attcaaggtc
    12601 ttttcacatt cttttcctac tactaatgat aaaataaagt aaacgaaaag gagtgaaacg
    12661 aaaatgtatg gttatggaat gtatggtttt ttagatccga catttctttt ggtcattctt
    12721 ggattagtta tttccggaat tgcgtcagcg tacgtcaata gtactttccg aaaatacgat
    12781 caagtgagaa gcaaaaacaa tgtgactggt acacaagcag cacaatatat attacaaagt
    12841 caacagataa ataatgtcgg tgttcaacaa attgccggag atctcacaga taactacaat
    12901 tcaggtaata agatgttgag tttgtctcaa gcaactgcac agtctacttc agttgctgcg
    12961 ataggtgtag cagctcatga atgcggacat gcggtacaag atgcttcggg ttatgtccca
    13021 ttgaagattc gtgcagcact tgttccagca gctaactttg gttcgatgat ttcgttcccc
    13081 ttgattatgg taggtgtatt gcttagctgg aactctacgt taatcaatat cgggattttc
    13141 gctttttctt tagcattact tttccaattg gtgacattac cagtcgaatt taacgcgtct
    13201 cggcgagcaa tccaaatttt gagtgaaggc ggactactga cggaagaaga agtaccgatg
    13261 gcaagacacg tattatttgc agcagcactg acttatgttg cagcagcgct ttcgacattc
    13321 ctgcagctgt tgcgcttgat cttattgttc ggcggcaacc gaagagatta aaataaagaa
    13381 gttgtgaaat cagcgctttg atctgagcta ataccgagag ttagctgatt gaataccatt
    13441 tatttggaat aagaggatgt gacaagaatt ttgtcacatc ctctttgttt tgttctcata
    13501 accttttttc atatacagtt catgaaccgc ttttattaac ttgccaaata acactgtatt
    13561 gtgcgttgta tccagataga aagtctccgt ttcatctgaa attttctcat gctgatctgt
    13621 aatgatcaaa tcagcatgtt ctgaatatgc ggtaatttta acagcatctt tgcgaaataa
    13681 ctgctgcaaa tggctttgaa gatgataatt tcctgtaaac tgtttggtta tctgcaaatg
    13741 gatgagtaac tgctctttcg tttctgtttg tagtaagtgt tggatcaatt gactaaggta
    13801 ttgactgatt tggtttcttt ccccattttt tgaaaaaatt gtatcgattt tttctcttaa
    13861 tttcttttcc tgtataaaag aactagaatg attggacgtg gcttctggaa agcaaagtgt
    13921 agaaaaacta ctgctggatt cacccaacag ttcgaaaaaa acaactgcca acacaagaaa
    13981 ataaaaataa attggtattt tattttctaa atggttgaga ggaaactgtt gagttaagta
    14041 agtcatcaat tgaccgactt gtcgacaaat aaggtttttg cttgtggaaa ataaaaaacc
    14101 aatctcctgt ttttgtcgaa aagagatttg atttggaaaa aaacaataga aaaaataatt
    14161 aaagtaggct ctctctgttt ctgtctcttc acaagggcga ctcactgaaa aagaagtaaa
    14221 gtattctgaa taatcatgtg tatgctgcaa taagtccatc aattcagtga tttcagaaga
    14281 agtttttgga aaatatgcct gttgtttgtt tcgtaatatg aataaagtta acagcaagta
    14341 gatatttttt tcttgttttg aaattttttc tatttgctca tctgtactgt tcatttttag
    14401 tgcatttaat tcaagtgagg aaaatggcca atcgttacct ccaaatgtat ctgaaagaaa
    14461 aaagtaaaga tagagacgga tagataactc atttccttca agagtacagc aattttttac
    14521 agataggatc cgtaaatgga attttattaa ggaatgattg agctgttttg tcagtttttc
    14581 gagataggag ggcgatatat aaagttgttc aagtaaatat ttttttggta cagcagtttg
    14641 tggataattg attagtaaca tcaaatagtt aaaacgattg gattctttta ggtagcataa
    14701 ttttaactta gaaaaaacag ctaacttttt agtttgatcg gtttctttgg tttggatctc
    14761 tcctttatga ttagaataaa taaattcatc aatcaataaa aattgcttga gtgatacatt
    14821 tatttttcgg atcagttctt tgattgtccg ttttggaata tgtaagtcat tggataattc
    14881 ttgtaaagaa caattatttt tttgaatgac catttgtaga acaagtaact ctttttttct
    14941 tgcttcaatt agcataaata cctccttttt attctgtttt tgtatatagt tagacaaaaa
    15001 ctgtgagtgg aaagtcattt cagtctgtgt tattctcaca gagtgtcgcc ttctttttta
    15061 tataacgt
//
LOCUS       DAZUJR010000072        14913 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.072, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000072 DAZUJR010000000
VERSION     DAZUJR010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14913)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14913)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14913
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.072"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(161..2158)
                     /gene="tkt"
                     /locus_tag="ACG804_002157"
     CDS             complement(161..2158)
                     /gene="tkt"
                     /locus_tag="ACG804_002157"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HFS4833078.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2260..2511)
                     /locus_tag="ACG804_002158"
     CDS             complement(2260..2511)
                     /locus_tag="ACG804_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HFS4833079.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2658..3281
                     /gene="lexA"
                     /locus_tag="ACG804_002159"
     CDS             2658..3281
                     /gene="lexA"
                     /locus_tag="ACG804_002159"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HFS4833080.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3461..3679
                     /locus_tag="ACG804_002160"
     CDS             3461..3679
                     /locus_tag="ACG804_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833081.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3968..4480)
                     /locus_tag="ACG804_002161"
     CDS             complement(3968..4480)
                     /locus_tag="ACG804_002161"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HFS4833082.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4494..6791)
                     /gene="recJ"
                     /locus_tag="ACG804_002162"
     CDS             complement(4494..6791)
                     /gene="recJ"
                     /locus_tag="ACG804_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HFS4833083.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6933..7376)
                     /locus_tag="ACG804_002163"
     CDS             complement(6933..7376)
                     /locus_tag="ACG804_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapA
                     domain-containing protein"
                     /protein_id="HFS4833084.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7377..8165)
                     /locus_tag="ACG804_002164"
     CDS             complement(7377..8165)
                     /locus_tag="ACG804_002164"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HFS4833085.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8162..9103)
                     /gene="rnz"
                     /locus_tag="ACG804_002165"
     CDS             complement(8162..9103)
                     /gene="rnz"
                     /locus_tag="ACG804_002165"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HFS4833086.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9280..9867)
                     /locus_tag="ACG804_002166"
     CDS             complement(9280..9867)
                     /locus_tag="ACG804_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HFS4833087.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10088..11401)
                     /gene="obgE"
                     /locus_tag="ACG804_002167"
     CDS             complement(10088..11401)
                     /gene="obgE"
                     /locus_tag="ACG804_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HFS4833088.1"
                     /translation="MSMFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGG
                     DVILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAET
                     GALLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVL
                     ADVGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLE
                     RPQIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNAT
                     ADLLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTN
                     FDHDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11689..12699
                     /gene="gap"
                     /locus_tag="ACG804_002168"
     CDS             11689..12699
                     /gene="gap"
                     /locus_tag="ACG804_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFS4833089.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12784..13719)
                     /locus_tag="ACG804_002169"
     CDS             complement(12784..13719)
                     /locus_tag="ACG804_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFS4833090.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
     gene            13905..14864
                     /locus_tag="ACG804_002170"
     CDS             13905..14864
                     /locus_tag="ACG804_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HFS4833091.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERSVS
                     CGMRTLYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPDNYPDFNSEF
                     GHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFK
                     SITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRNGLPKSMDFRK
                     VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
BASE COUNT         4219 a         3292 c         2626 g         4776 t
ORIGIN      
        1 tcaagaaaca caaactaatc cgaagaattc tttgttttgt catttaaatg taacatagcc
       61 gaaaacgaaa agtaatattg atttattctt ctaacacata aagaacagct gtctccaact
      121 tgcagacagc tgttcttatc agtcaaacaa ttgcttggat ctatgatagt tgattgtacg
      181 tattcacgac attttctact gtaaatccaa attcttctaa aattttagtg ccaggggcag
      241 atgcaccgaa atgatcgatt gtaatcgttg cgccctctgt tcctacgtag cgttcccatc
      301 caaatgatgc agcagcttcg atagccacac gtttcttcac tgatttagga agtacacttt
      361 ctttatattc agaagattgt ttttcaaaga ggtcaaagct tggcatagaa acaacagaaa
      421 catctttgcc tttttcagcc aattcttttt gagctttcac agccaaatca acttcagaac
      481 ctgttgcaat caaaatacct tctggtgttt ctccttgtga tggagaaaga acatacgcgc
      541 cttttttcac catttcatct gctacttctt ttgtagaagg caatactgga aggttttgac
      601 gactcaatac aaggatagta ggcgcatctg ttgtctccat cgctactttc caagcagcac
      661 gtgtttcatt tccgtctgcc ggacgaatca cttgaacacc aggcatgcag cgaacagatg
      721 ctagttgttc aatcggttcg tgcgttggtc cgtcttctcc gacagcaacc gagtcatgtg
      781 ttaagacgta aacaacagga gtatgttgga ttgctgctaa acgaactgct ggtcttagat
      841 aatcgacaaa gacaaagaat gttccaccgt agatacgagt tccgccatga agttggatac
      901 cattcatagc cgaagccatt gcaaattcgc ggacaccgaa ccagatgttg cgtccttcat
      961 aatgttcagg agtgaaatct ttatctgcag ccaccattgt attattggaa cctgacaagt
     1021 ccgctgaacc accccagaag cttggtatag ctttcgataa ttcttggatg acttctttac
     1081 ttgaaacacg gcttgcttga ctgcttccaa cttcataagt tggcaattct gcatcccagt
     1141 tttctggtag tttgccatca aaagcatctt caaattgttg tgctaattca ggataagctt
     1201 ttttataatt ggcaaacatt tcattccatg catcttcagc tttttgtcct tcttctatca
     1261 tcgtttgatg gaagcgggca gctacttctt ctggaacagt gaaatctgga tactcccaac
     1321 cataaacttc tttagccatc ttgatgccat cttcaccaag aggagcacca tgaacagcag
     1381 atgttccttc tttaggagca ccatagccga tgactgtttt tacttcgatc aatgttggtt
     1441 tgtctgtttc agcttttgct tcttcaatcg ctttagagat tgcttctagg tcatttccgt
     1501 ctttcactaa gatatgttgc cagccatatg cttcatagcg agcaccaacg ttttctgtga
     1561 aagcttttga agttggaccg tctagtgaaa tatcgtttga atcgtataaa acgatcaatt
     1621 tccctagttt catatgacct gccatcgaac ttgcttcttg agatacccct tccatcaagt
     1681 ctccgtcacc gcatattgca tacgtatagt gatccatcac attaaagttt tctttgttat
     1741 acgttgctgc aaggtgcgct tctgccattg ccataccgac agccattgca atcccttgtc
     1801 ctaatggccc tgtagtggct tctacaccat ctgtatgatg tacttcagga tgtcctggtg
     1861 ttttagaatc ccattgacgg aattgtttca aatcatcgat tgtcacttga tagccagcta
     1921 aatgaagcaa gctatacaac attgctgacc catgtcctgc cgaaagaacg aaacggtcgc
     1981 ggtcagccca gttttttgat gtcgttggat ttactttcag gtgttttgtc cataacgcat
     2041 atgccatagg tgctgcgccc atcggcaatc caggatgtcc tgagtttgct ttttggactg
     2101 cttcaatact taatgtacga attgtgttaa cgccaagttg gtcaattttg tcaaacaaaa
     2161 taacccctcc tattaattta ggtttttttt acctttattt cttacacttt cattctataa
     2221 gatgtcacac gaaaaagcaa tctttttcag tattttttac taaaagttgt catttcggtt
     2281 gtgtaagcct tttttctttt ggatttcttt taatttttcc ggggtcacgt cattgccctc
     2341 aggatcgacg actttcattc cttcgatatg atgacgcata ccggaacgaa aagcttccaa
     2401 atactctttg cgcaagttga tttgttcttg ttcttcggct tttgagagac cattttcctt
     2461 ctttttacgt gcaagttcat tgatccgctc tattttttca ggtgacagca tgctcagccc
     2521 tccttttact ctccttcata ttatataaaa actgaaaaaa aaacaactag ataaactaaa
     2581 taaaatacga acattcgttt gatttagcgc tttttatatg gtactattta tttatcaagt
     2641 gaaagaaggt gtaccttgtg gcccgacaaa ctgaatcaag acaaatcgaa gtcttacgat
     2701 atatccatga acaagtaacc caaaaaggat acccgccgac tgtccgtgaa atcggggaag
     2761 ctgttcagct ttcttctact tctactgttc acggtcatct tgcacggctt gaaaaaaaag
     2821 ggtttatcca aagagatccg acgaaacctc gtgcaatcga gttgacaaaa caaggtttag
     2881 aaaagattgg gattcgtcca acaactattc cagtacttgg cgtcgtaaca gctggagaac
     2941 ccattttagc agtagaggat gcttcagact tctttccaat ccctcctaat ctttcttccg
     3001 aagaaggcag tctctttatg ctgacaattc gtggagatag tatgatcaat gctgggatat
     3061 tggatggtga caacgtgatc gttcggaagc aagaaactgc tcaaaatggc gatattgtca
     3121 ttgcaatgac tgccgaggac gaagcgactt gcaaacgatt ctataaagaa aaaaactttt
     3181 tccgtctgca gcctgaaaac gacttgctcg aaccaatcat cttagatcaa gtatctatat
     3241 taggacgagt agtaggactt tatcgtagtc atatctatta attgctacta attaaaagaa
     3301 aactttttaa aaagagtttg agacgttggt ctcaaactct tttttcgccc gggttcttct
     3361 tctttcaaat ttttatcact tccctcttta caaaccgaac aaatattcgt atactaaata
     3421 tacgaacaat tgttcgcata aattaaagag gtgagaattc atgaaatcaa tgagacgtct
     3481 tggcttagta ttaactgttt tgtttttagg tattattatt ggtaatttcg gcatacgtcc
     3541 agctttactt gtgtttgttc cgttatttac tttgtggttc atgttgtggg atgaaaagaa
     3601 gtaccgtcaa tctgagcggc gcagaattca tgaagatcat ttctatcatg agccctacta
     3661 cagatccagg caatcataat aaggattgac tgctaattat tcaaaagaca agaagttaaa
     3721 cttttacggg ggtgtgacaa aaatcggtca catccttttt ttcgaataaa cggtgttcta
     3781 aagccagttt ttcggtatta agtcaaattg cggaaaaagt gattttttaa acttctactg
     3841 gtctttgctt gtttccattt ataaaaaaat agcgaccctc aaaagtcaga tagagaatct
     3901 gacttttgag ggtcgcttta aaatcgcttc tttaagaata acatcaagaa tagcttcttt
     3961 tttctgctta atattccatt aatgtaatga tgtcatatcc tttgattttg tcgcgtccat
     4021 ggagatccat caattcgatc aaaaatgcgc agcctacgac tacaccgcct aattgttcga
     4081 tcagttcgat cgtcgctttg attgttcctc cagtagctag caaatcgtca caaatcagca
     4141 cacgttgacc tggtttaatg gcatccttat gcaatgtcaa tgtatctgtt ccatattcta
     4201 atccataagt cacttcgatg gtttctcgag gtaacttccc ttttttgcgg actggggcaa
     4261 aaccgactcc taactcataa gcaacaggac atcctacgat gaatccacgg gcttctggcc
     4321 caactaccat atcaattcgt ttttcttttg cataatttac gatttgttta gtagcttccc
     4381 gataagcgtc accatctgcc atcagtgggg aaatatctcg aaacacaatt ccttttgacg
     4441 gatagtcggg aatactggca atataatctt ttaaatccac tctttgtttc ctcctaggtt
     4501 gttaaccatt tctttatggt aggaatatcg ctcaaaagca aaaattcctc aactttgatt
     4561 ttattgagcc gtcgctggta taatctgctc tcagtcaaag gatgactttc tgggctagcg
     4621 actttttgta aaacaccgtt ctctattgta acaaatttca attcaaaaaa cacctgtatc
     4681 ataaaaatta ataatttttc agggatacgc aaatattgag ctattgcttt tattttatga
     4741 cgtatatcaa ttcgttcttg agaatggatc aatttaaaca attttgcgta ctgttctctt
     4801 gtgcctaccc cattcaaata ggcctcatca ggtgaaatcc ccatcagata aacacgattg
     4861 aatgaataag accgaaaaac ttctttcaga tccgctaaat catctggaca atccataaca
     4921 actagagagt ttggttttct tttttcaatt attgccttta cagaatctag tccttcgaaa
     4981 acaatcgcag cttcctggat aatctcaggc acgaatttca acgtcgaaga atcaaatgct
     5041 aaataaaggc taccttccga cgttcggctc tgttcacgga aacgttttgc ccgccaatca
     5101 aatacttgca gaccacccac agaaaaatca gataccatca gctgcggttt cttacgcccg
     5161 ttccattcat tgatcgaaag ctttcctacc acatctacct gattattcag cagttcttct
     5221 tcttgagtac caaaaccaaa agcgaccgca tcaagctgac tcgatgcatc ggaaaggaca
     5281 aatttcagat gctgttggtt tgctccgatt cttttgatat tttctgcttg gacttgtcga
     5341 aataaaaact gaggcaaagg attatccgta ccaaatggcg ccaatagttt cagctcatca
     5401 attcgctcta ctgttacttc atttggcagc aatacttcat caattctcaa ctcaggccct
     5461 ctcatcaagt caatttgatg atcgactata tattggttca tcttctcctg tagtatagtg
     5521 acattttcac ttggcatcgt taaaccgact gctgcatgat gtcctccgaa gtaagtaaat
     5581 aaatctcgca tctggtcaag catttcaaaa agattcaagg cttcaatact acgtccagat
     5641 cctttagctg atccatcttc ttttaaagta aggacaagcg ttggtttacc cgtttcattc
     5701 attattttcc cagcaacaat gcccaaaacg ccttcatgcc atcctcggtt taccaataga
     5761 tggatatgat tctccttatt gaccatcgct aatgcttctt gtgttatctg ctctacgatt
     5821 gcttttcttt cttcattgat ctcattcaat ttttttgctt gaacggatgc ttcctcttca
     5881 tcaaacgtcg caagtaacga gacggcagga cgtggatcgc ccatccgacc gattgcattt
     5941 agtctgggag caatcgaaaa accgatcgtt gtttcgtctg cgtccctcat ttttacgccg
     6001 ctttcttcaa atagcgcctg aagtcctatc cgttctgaat gatgaatggc atcgattcct
     6061 aatgaaacaa ggattcgatt ctcatcagtc aatgaaacta aatcggcgat cgttcctatc
     6121 gctactaaat ccaaaaattc tgcaggcggt tcttccaata atgcagaagc tactttgaat
     6181 gctactccga ctcctgccaa atctggaaat ggatagtgcc ccgctggatg acgagggtga
     6241 acaatcgcat aagcgtctgg taaattctca ggtagttcgt gatgatctgt aatgatcacg
     6301 tctacaccag cttgctgagc gtatgctacc gcatcatttc ctgctacccc gttatcaaca
     6361 gtgatgatca actggattcc ttcttcgatc ttttcttggt ataccgattg gtttggtcca
     6421 tacccatgct caaatcgatt tggcaggaat acttctactt ctgcaccaag taattccagt
     6481 gtttctttca ttaccgttgc actggtgatc ccatctgcgt cataatcacc gtaaacgagg
     6541 attttttctc cactgattac agcttcttgg attcggctga ttgctttatc catatcgtgt
     6601 atcagatacg gatcatgtaa ttcttgttcc tttggatgta aaaatcggtt gatatccttt
     6661 tcctcatggt aacctctttg ccacagtaac ttaccgacaa atggagataa tttcagttca
     6721 cggatcattt ggagaaagga ttcagaaggc tctgtctcgc ttaacttcca atcaaaattt
     6781 gcttgtctca ctttctcact cctaacttag ttattatagc aaaggaaatc agcaaaaaaa
     6841 agcagaaaga aagaataaaa acagatcaga tccgctagac agatgttcag caggacctga
     6901 tcttttgtac gaccatttat gaaatatccc tattagtcaa aataattgaa gctttgtttg
     6961 ggcgattgag ttttttgttc ttccggcgct ttcaattgac tgatttgtgc ggttttcgct
     7021 tgtaactccg cctgataagc agcttccaac tccgcacgtt cgtttctaaa ctcgcgttgc
     7081 tgttcttctt ttgcttcttc aattttcttt tgaagttctg tttgatattc tgacatttcc
     7141 tgagtcagct gtttgatttg ctttttttgc tgccatagtg ttgccgaagc agtcaaaaat
     7201 acaatcagtg caccaatcag cgcagaaccg atgatcacta agatcaatgg cgcagaaaag
     7261 gaagtgaagc caaaacttac aggaacattt ttattgttca atacagcaaa aagaacaata
     7321 atcaaaacta aaacaaatcc aagaatcaca ttgctttgct ttttcaattc cttcacctac
     7381 tttttgttaa aaattccgct ggctaaataa tcaccaatcg ttggaaacag cgtataaaat
     7441 tttgatgcaa cttctaaaat aaacggttga ttgatttccc gttttggatg tctcatattg
     7501 cggacgatca tttttgccaa cttggcaggt tctaaaacga tttgtccgac tttttccaaa
     7561 tagcttccgc ttggatcagc cttatcgaag aaatttgtct cgattggacc tggattcact
     7621 gtcgtaacag ctacgccaag tggtttcaat tctaatcgca aagcgttgga gaagccaagg
     7681 actgcaaatt tcgtggcaga ataaaccgtt gattttgcag ttgccatttt tccagccata
     7741 gaggcgatat taatgatatg accttgtctt ctttctgcca tatcgatcgc aaatttttgt
     7801 gtcaaaacca tcattcctaa gatgttgact tcaaacatat cgtatgcttt tccaaggtcg
     7861 aatgtaagga agtcttcgaa aatcccaaaa cccgcattgt ttaccagaat atcgacgcgc
     7921 ccgacttctt ccatcacctt ttcatataat tcgtccacgc tttcaggatt gctgacgtct
     7981 accttgaaag cataagcctc tttgccgctc aagcgtctgc actcgtctct gacaccttct
     8041 acaaatgcca ttcttcgtgc gcaacttata acgattgctc cttgctttgc tgcttcataa
     8101 cagatttgtg cgcccagacc gcctgaacta cctgttacta aaacaacttt atcttctaaa
     8161 ttcatgcctc ttcctcctcg cgaaatggaa tctcaatgct atcaaaatct ttcataatcg
     8221 tcgtgttttc aaacacttct tgtgcttctt tttcaagctc taaagctgct tttcctaaat
     8281 atctcgcact gatatgagta agtagcagcc gttttgcctg cgcttctttt gcaacttcag
     8341 cagcttgatg agtcgtggaa tggaaatagt tgtgcgccat tcttgcttca tctttattaa
     8401 atgtgctttc atgtaccaga atatcgctat tttccgcaag cacaacggaa ttatgtgttt
     8461 ttctcgtatc gcctaaaata gtcacgattc gtcctttttt atctggacct acgaaatctt
     8521 ttccattgat cgtccgccca tcttctagtt ggatcgtttc accttgcttc agtttgccgt
     8581 acagtggtcc agctggaata cctaattctt ttagacgatc cacctgcaat tctcctttat
     8641 gatcatgttc aaccacacga taaccaaaac tgtcgatccc atgatttagt ttttttgtat
     8701 aaacagaaaa ttgctgatca gtaaaaatcg gggctgtttc atttagctca atgaatttca
     8761 gcggataact taaacgcgtt tgcgaaatac ctaaagagac ttttatgtat tcctctatcc
     8821 cttttggccc gtaaatctct aatggcgtat ccccaccttg aaatgaccgg ctgctgatga
     8881 gcccgggaag tccaaaaata tgatcgccgt gtaaatgtgt aatgaaaatt ttaccgattt
     8941 ttctcggacg aatagtcgtt cgcaaaatct gcatttgcgt gccttcgcca cagtcgaaca
     9001 accaaacttc attgcgctcg tctaaaagtt tcaatgctat acttgtcaca tttctatgtt
     9061 ttgcaggaac acctgcacct gttcctaaaa attgtaattc cataatctac ctgactttct
     9121 ttaagttcct ctttaatttt agggtaaaaa gaagggataa tcaaccgtaa gtcgagaatg
     9181 ggttcaaatt aaaaataacg ttctaaagcg atagcgtttt ctttgaaaat tactataaaa
     9241 acagcagcga acccgtttga gatcctctgc tgttttttat taatttgaag atccagaact
     9301 ttcattgtcg ttggaagttt gcggatgttt gtccttccaa gtcttttgtg cagcttcttt
     9361 cgcatgattt tcagcttctt tcgcatcatg cacatctttt tcgacatctt cataatccaa
     9421 gcgagtaatt tctccgccta attccatcat taccaattga ttcagtgggc gattgtcctc
     9481 ttcatcagca atcaagatca gtcctgtagc tccttcaccg attttatttc ctacaaagtc
     9541 gaacacggtc tgggcatctt ttatttcttt ggcatcttgt gtcgcaccga tcattcctcc
     9601 ggcaaaccat cctaataaaa tccctagcgg accacctaat acaccaacca acattccgat
     9661 taatccaccc gtagaagatt tgttattacc ggtaaagtcg ataaaatctt ctattttgaa
     9721 ttgatgtgtc ccattaggat catggctgac aactgccatc tgttctcctt taatcgaacg
     9781 aacagcatgt aactttttga tttctgaaaa tgcctgatat gcctggcttt ctacttgaaa
     9841 atttaaaatg attactcgtt tgctcattaa aaacgcccct ttcatacctt cttgttattt
     9901 attttacctt taattgaaaa ataagaaaag aaaagcactc tttttttcca ataaaatagg
     9961 gctgtgacaa aagtcgtatc acagctcctt tttccgaata aacggcgttc ttgaagctga
    10021 tcacttctgt cacaacctcc cttaaatctg aatctatatt ttttggtatt tgtttttatt
    10081 tgcttgccta ttcgacaaat tcaaattcaa actcaccgat acgtacaagg tcgccatctt
    10141 tcgcaccgcg tgcccgaaga gcttcatcca cacccatacc acgtaattga cgagcaaaac
    10201 gcatcactgt ttcatcatga tcgaaattcg tcatttggaa taatttttcg atcttctcac
    10261 cagataagat ccacgttgca tctgaatcac gatcgatttg gaactcagga ccttctggat
    10321 tgaatccata gtgtacagtt tcttcttcca gttcttcttc gtacaatggg aattctggcg
    10381 ttacttctaa caaatctgct gtagcattca ataacgcgtc caatccttgt cgagtcactc
    10441 cagaaattgg aaatactggg atgtcatcag caaattcatc ttctttttcc ttgttcagct
    10501 gttctttgaa tttcactaga ttttccggtg catccggcat atccattttg tttgccacga
    10561 tgatttgcgg acgctctagc aagcgtaagt tataagtaga taattctttg ttgatggcaa
    10621 gatagtcttc ataaggatct cgtccttcca tcccactcat atcgatcaca tgtaaaatta
    10681 ctcgtgttct ttcgatatga cgaaggaatt gtgtacccag cccaacacct tgcgaagctc
    10741 cttcaatcaa gcctggcaag tctgctgcgg caaaacttct gccatcactt gtagtaacca
    10801 ttcctagatt aggtacgagc gtcgtgaaat gataagcgcc gatttttgga cgagcagatg
    10861 aaataacgga tagtaaagtc gatttcccga cagatggaaa acctacaagt ccaacgtctg
    10921 ccaatacttt caattctagt tcgatttttc gctcttgtcc tggttcaccg ttttcagcaa
    10981 tttccggtgc aggattccga ggagaggcaa aacggatatt ccctcgtcca ccgcgtccac
    11041 cttttgccac aactagtgtt tgaccatttt caattaaatc tcctaaaaga gcaccagtct
    11101 ccgcatctcg gacagtggtt ccttgtggta ctttaacata ggtatcttct gaaccacgac
    11161 cgtgcatccc tttactcatc ccattttcac ctggctgcgc tttgaaatgg cgattgaacc
    11221 gaaaatccat caatgtacgt aacccttcat cgacgatcaa gatgacatcg ccgccacgac
    11281 caccgtctcc gccagccggt ccgccgtcag gaacgtattt ttcgcgacga aatgcaacca
    11341 ttccgtctcc gcccttgcca gctttcacat cgatcgttac ttgatctaaa aacatggaca
    11401 taattaagtc ctcctattat tcatttattt atttgactgc ctgaatttcc acaataaaca
    11461 aaagtcttac ttattttatc ggtgaaatct gattttgtct atcatttcag caaaaagatt
    11521 gtttaccttc ttcttttttt atcatttggt aaggtttcca accttttttc tgctaccaag
    11581 tataattttt tgacaaaata ttctttgcgt agcagaataa cagtgtatta attgtattaa
    11641 ttgaggatgc cgtttcacag cacccctaat aaaggaggaa cttttgatat gacagtaaaa
    11701 gtaggtatta acggatttgg gcgtattggc cgtctggctt tccgccgcat caaagaagtc
    11761 tcagatgata ttgaagtagt agcaatcaac gacttaacaa gtccaactat gttagcacaa
    11821 ttattgcaat ttgactctac tcatggtact tatcctggca cagttactgc aacagaagac
    11881 tcaatcgtag tggatggcga agcaactcgt gtttatgcag aacccgacgc aagcaaaatc
    11941 ccttgggcaa aagaaaacgg tgtagatatc gtactagaat gtactggttt ttatacatct
    12001 gaagaaaaag caaaagcgca tttagatgct ggtgtcaaac gagtagttat ttctgcccca
    12061 gctggtgcta tgaaaaccat cgtctataac gtcaatgatg atacattaga tgaaaacgac
    12121 aaaatcatct cagcaggttc atgtacaaca aactgtttag cacctatggc ttatttctta
    12181 aataatgaat ttgggatcga agttggtaca atgacaacag ttcatgccta cacttccaca
    12241 caaatgctct tagatggacc tgtaaaaggc ggtaatttgc gtgctgctcg ttcagctgct
    12301 gacaatacta tcccacattc tactggtgct gcgaaagcaa tcggcttagt tatccctgag
    12361 ctacaaggaa aattacaagg acacgcacaa cgtgttccag tcgttgatgg ttcattaact
    12421 gaattggttt cagtattgaa aacaaaagta actgctgatc aagtaaacga agcaatcaaa
    12481 aaacacacag ttgacaatcc ttcattcggg tatgatgacc gtcaaatcgt ttctagcgat
    12541 gtcattggaa caactcaagg ttcgatcttt gacccaacgc aaacagaagt aacaactgct
    12601 ggtgatttcc aacttgttaa aactgttgca tggtatgaca atgagtatgg atttacttgc
    12661 caaatgattc gcttactaga aaaattcgct aacttgtaat ttgatagatc aatcgataaa
    12721 agaagccttt gactggatcc agtcaaaggc ttctttcttt tcatccccta cttttaaact
    12781 cgttcaatga acatattggc ttaaaaattg ttggactact tgctgatatt tttcaggatc
    12841 tgtcttgtat gcttccgcat gctcggctcc ttttacaaca tacttttctt ttggtccctt
    12901 cgttgcacga tagaccttat ctaacatttc aaatggtaca aatgtatctt cgtctccatg
    12961 tataaagagc attgggcgct ggtttttctt caattgttcc actgcatttg cttcaccgaa
    13021 aaagtagcca gcacggactt ttgtcactag actcgttact tgcataagcg gaaatgctgg
    13081 aagactaaac atatcgtcta gctgataagc aagctcatca tgaacggaag aataaccgca
    13141 atcttcaatg attgctttca cattatctgg tagtttttct ccgctagtca tcataactgt
    13201 tgctgctccc atgctgacac cgtatagaac gatttcttgc gattttccat tgttttctag
    13261 cactttgttt atccactgta catagtcttt acgctctggc catccaaatc caatgtaatc
    13321 cccttcgctt tttccatgtc ctcttgcatc aggaacaagg acattgtaac ccatatcatg
    13381 aaacatcttt gcgtaattgg tcatcgtttc agcgtttccc atatagccat gagccacaag
    13441 agctgttttt tcacttttcg tttcagcagg aagataaatc gctgataatt tcagaccgtc
    13501 ttttgaagtg atggtccaat cgcttcggtt ttcttttgaa ctaaaccatt tatgtgcatc
    13561 cgtttctttg gatgtctgtg ttgtaccagg tgtatcttcg tctaaaaagt ctttctcaga
    13621 aggcacaaca gcataattat aaaaataatt ccctgcaaac actaacgcaa caatcagagc
    13681 taaagcgacg cctaaaagga ttttcatcca aagtttcata aatcatccat ctcatttctc
    13741 ttttttcata taaccttgaa ttagtataat caaagaatct ctactatgca atgttcattt
    13801 ttataacccg cgaattgtaa aattaagtta gaaaaataaa aaggcattta tggtacactc
    13861 aaattgtatt tccgacgaaa gaaaacaaag gagtgtaacc ataaatgacc tacaaacatc
    13921 ttaccataga cgaactgaca atgatagaat catattatct tcaacataat aagccggttg
    13981 aaatcgctaa ccgaatggga cgtgctatac aaactattta taatgtagtc aataagttca
    14041 agcaaggcaa gactgctctt gattattggc accagtataa agaaaataag aaaaaatgtg
    14101 gtagaaaagt cattcaatta cctgctcatg aagtagatta cattaaagag aaagtcactc
    14161 ttggttggac gcctgacgtc attatcgggc gaaaagaaag gtctgtttca tgcggtatga
    14221 gaacacttta tcgtttattt tctaaaggaa tatttgatat tgacacacta ccgatgaaag
    14281 gtaaaagaaa acccaatggc catcaggaaa aacggggaaa acaacagtat cagcgctcaa
    14341 tccatgatcg acctgataat tatcctgatt tcaattctga gtttggtcac cttgaaggtg
    14401 atacgatcgt tggcattcat cataaaagtg ccgtcattac tttagttgaa agattatcta
    14461 aagtcattat cacgattaaa cccaacggcc gtaaggcatt agatattgaa actgccctta
    14521 atcaatggtt ttctcgcttc cctaaaaact tctttaaatc tattacgttt gactgtggaa
    14581 aagaattttc taactggaaa gccattagta accaacatga tattgatata tattttgcgg
    14641 accctggaac accttctcaa cgcccattaa acgagaattc taacgggatt ctgcgtcgta
    14701 atggactgcc gaaatcaatg gattttagaa aagtgaatca gacatttatt tccagtgtca
    14761 gcaatcaacg taatcatatt ccaagaaaat cattgaatta cagaacacca atcgaaatat
    14821 ttttgagcta tgtacaagaa gcattttatt ctagcttaat ttgacaaatc ataacctata
    14881 aaaaaacaaa ataaaaaagc agaaataact ggc
//
LOCUS       DAZUJR010000073        14777 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.073, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000073 DAZUJR010000000
VERSION     DAZUJR010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14777)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14777)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14777
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.073"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            159..458
                     /locus_tag="ACG804_002171"
     CDS             159..458
                     /locus_tag="ACG804_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFS4833092.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            953..3118
                     /gene="acm"
                     /locus_tag="ACG804_002172"
     CDS             953..3118
                     /gene="acm"
                     /locus_tag="ACG804_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HFS4833093.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(3390..3875)
                     /locus_tag="ACG804_002173"
     CDS             complement(3390..3875)
                     /locus_tag="ACG804_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HFS4833094.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    3965..4310
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            4355..4996
                     /locus_tag="ACG804_002174"
     CDS             4355..4996
                     /locus_tag="ACG804_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFS4833095.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            5015..5650
                     /locus_tag="ACG804_002175"
     CDS             5015..5650
                     /locus_tag="ACG804_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFS4833096.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            5668..6483
                     /locus_tag="ACG804_002176"
     CDS             5668..6483
                     /locus_tag="ACG804_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HFS4833097.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            6802..8238
                     /locus_tag="ACG804_002177"
     CDS             6802..8238
                     /locus_tag="ACG804_002177"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFS4833098.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            8427..10874
                     /locus_tag="ACG804_002178"
     CDS             8427..10874
                     /locus_tag="ACG804_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HFS4833099.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            11104..12171
                     /gene="rlmN"
                     /locus_tag="ACG804_002179"
     CDS             11104..12171
                     /gene="rlmN"
                     /locus_tag="ACG804_002179"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HFS4833100.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            12161..12367
                     /locus_tag="ACG804_002180"
     CDS             12161..12367
                     /locus_tag="ACG804_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833101.1"
                     /translation="MPNNRILLVFSITIKGAVFLIKELFNLNKRKDSIAKAIKLFLTR
                     KTLIKQRNVLNLMTACLMGVLAII"
     gene            complement(12364..13467)
                     /locus_tag="ACG804_002181"
     CDS             complement(12364..13467)
                     /locus_tag="ACG804_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HFS4833102.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            14019..14567
                     /gene="aac(6')"
                     /locus_tag="ACG804_002182"
     CDS             14019..14567
                     /gene="aac(6')"
                     /locus_tag="ACG804_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HFS4833103.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         5105 a         2391 c         3096 g         4185 t
ORIGIN      
        1 tgatttaatt tagaatgttt ttaaaataaa aatcgttgcc ataacagtgt attgaaaggt
       61 tttaacaatc cagtaatgat ttaaaaaaat ctagatgtag cgtatacttt gtttatagaa
      121 tgtagtggga agaaatatat ttttgggagg aaatcgtgat gtctaaaagt gaagaaatag
      181 aaaacatggt actaaaatta tatgatctcg ttttaaatcc agagatcaaa gaaaaggaac
      241 gtatactttt gatagacgca aagacaggct tagaaaaagg tcagtattat cctaaagtca
      301 taaataattt ggaacgtagt ttacgtccgt tagcaatcag gggagaattg tctaaaccag
      361 tatcaccgtt ttatatggag atatcaacaa taggaaaatt tgaaaaagaa ttaggtcgag
      421 gaatggcttc ggcaccgatt acttttgggc atttataaaa acgagttatt catctcaatg
      481 aattaaaaag tatagtcaat ctcataatgc aggctaggtt catttatttg aacagagtct
      541 gtattttttt attctaaata aagaaacaga tgtttcttta tattgtattt tatcctttaa
      601 ttaacacaaa aacagctagt ataaactaat aatgttaatt aaaagtgtat tttatgaaac
      661 tatcgttatt tattaatgtt gcatttttgt aagttaaaaa ttggaaatat agattgaaaa
      721 aatgaaagca ataagtaaaa taaaatgaat atatgcgaaa aaataattta cattaggaaa
      781 aaccttgtaa aaacagtttt ttggcatatt tattttttat aaatatttgt aaaataacta
      841 tcaatttttt agttaaaaga ttggaaatga gtgggggagg aattgaagaa aggatttttg
      901 agagatgata tagtaggttt tatttttagt taaaataggg gagatagaaa aaatgaaaaa
      961 gtgtagaaat attattttat caatgttatt tattattact aatataacat cactgattcc
     1021 tgttcatgtc tatgcggatg caggcagaga tatcagcagt aatgtcactt cgttgaccgt
     1081 ggacccaacg aatattacag atggaggaaa cataaaagta aaattctcgt ttgacgaaaa
     1141 aaaacaaaat atccaaccag gtgattatct ttggatcaat tggccaagtg aaggaaatat
     1201 tcgcggtgaa ggattccaaa aagaaatccc attaatgatt gaaaataaaa atgttggaac
     1261 tttaacggtc agaaaagatt ctgcgcaggt tgtgtttaat gaaaatatta aaaacctaga
     1321 ctcagtagaa ggttgggggc aatttgagat acaggccaga aacgtaaccg ataccggtga
     1381 agaaaatacg ggaccattca ccgtgacgag cggtgataaa acagctactg taaatgtgac
     1441 aaagccagct tctggttctt cttctagcgt tttttattat aaaacaggag acatgctacc
     1501 tgaagatact aagcacattc gatggttttt gaatattaac aataacggca cttatgttga
     1561 acaaccagtt aaaatcagtg atgaaatcca aagtggacaa agattagatc caagtacgtt
     1621 tgaaattaat caaatacact taggtgaaca gaaggtttat agaggagaag agggaatcca
     1681 acaattttta caagatttcc ccagcgctac atttaatttt tcagtaactg ataattacat
     1741 tgaaataact ataccaaaaa actttgtcaa tcttaggaaa ataatggtga gttataagac
     1801 gatcatagaa aacccagaac aaataaattt tgagaatcat tcggaagctt ggtttaaaga
     1861 atttaataaa cctgctgttg atggagaaag tttcaatcat acagttaaaa atatttcagc
     1921 ttctggtgga gtcaacggta cagttagagg cgaattgaag attttcaaat atatcaatga
     1981 cacagagatt ggtatcccaa atgtgacttt cgaattaaga cgagcagatg aacagcctat
     2041 tcaaggacag tctagtatcc tgttgacttc gaatgaacag ggagaagcta gtatcaaagg
     2101 cctgcaagta ggagactatg ttgtaaaaga aaaagaagca cccaattgga ttgattttga
     2161 tccactaagt tcaaatgaac tcaaattctc cataaacgaa aatgatacag agggagtcag
     2221 tttacctatt tataacaaga aaaaggttac gaacatcaca gcaactaaaa tttggaacgg
     2281 tggaaccact ccaagaccga gtatttattt taaattattc agagcaagta caaacaattg
     2341 ggaaccagtt cctgatgcag aaacaaaacg attagacaat ggaataactt cagtgacttg
     2401 ggaagatatc caacagtatg atgatagtgg aaacgaatat acgtttaaag tgcaagaagt
     2461 agatcaaaac ggaaatgatt atgtcccttc aggttatcaa aaaattgaaa acgggctagt
     2521 cgttacaaat gagaataaag aagtcatttc agtctcagga caaaaaacat gggaagacaa
     2581 tgagaaccaa gacggcaaac gaccgacgac gatcacagta aatctattag ccgacggtca
     2641 accgatccaa cacaaagaag taagtgaaaa agatgattgg cgctatcgtt tcacaaatct
     2701 gccaaaatac agagacgggc aagaaatcat ctatactgta acggaagaca acgtgcccga
     2761 atacagtacg acgattgacg ggtataacat caaaaacagt tatacaccgg aaaaaacaaa
     2821 tatatctata ccaggtagcc atataacacc gtggaaaaat tttccagaga agacagagag
     2881 agagaaaatt agaaatctat tctctcaaaa attgcaaata tttgctcata caggagaatc
     2941 cagcgaacaa agaagcaatt atattagtaa gagagctgta cctaaacaga taacaaataa
     3001 atcaaaaagc attcttccta aaacaagtag taaaaaatct agttttgctg taatcattgg
     3061 tttattgata gtaactatct gtgctgggat attcttacaa aaatataaaa aagtttagtt
     3121 agaatataat attttttgtt aaatatgact gaaatcaaaa gaataaaatt ccgatttata
     3181 atcgaaaaaa gaagcatttt tatatatgct tcttttttcg tagaatcaat aaatatggat
     3241 ttggctaact atggaagaat actcgtatta gttttcagcg ttcatactag ttgttacatt
     3301 gtttgattgg ccaaaagaat ttctgatata ttttgtgcta aataaagaaa aagacgcttg
     3361 aattgggaaa taagaaaact actctatcat tacaaatttt cataaactgg cagatgttct
     3421 aagtaaacaa gtatcttttc aaagtcggaa aaatccataa tcaacgtagt ggtattgata
     3481 tttggatgaa agcctacggt atcttgacga tcaatagcag catcgatcac gacttggatt
     3541 tttttctctt tgtcgtgcat caatgctaat ggagtcactg tacctgctgg aacgcctagg
     3601 aggtcaggaa gctgttcttc agaaacaaaa gataagcgct tttcttttaa ttgttcagct
     3661 agttgtttta aatcggcgtg cttttcatca ggcaagatga caagatagat ttgttttcct
     3721 tttcttgatt tcaataatag attttttact tgcggaccag gtagggaaaa agggacattt
     3781 ttgactgacg taatcgcagg atgatcgact ttttgaaaag agatacccag tttttttagt
     3841 agttcataag cttcttgttc ggttgcacga ctcatcgcgc atcaccctcc tttttttatt
     3901 agtgtatcat aaaaaagagt tgacaaatga aaaataatca tgtaaattac acgtaaagtt
     3961 aaaacaaatg acatcgaaaa gaagagtagc cgttaggtgt ttttagagag tctctggttg
     4021 gtggaaagag gcagcagtta accgtgaaac acatcttgga gtcgattttc tgaagcgtat
     4081 agtaggaaaa tccggggagc ccgttacagc tgcggtcgtt gctagatgac cagataaggc
     4141 tggcttttcc gtgaggagtc ggtaaaaaaa ggtggaacca cgtgattaac gtcctttgat
     4201 cttcggatca aaggactttt tgttttcatc tgaacggcaa cgactgtgtg aggttttttc
     4261 tgcaaggaaa aaataaacag aggtggaacc acgtataata cgtcctcttg gcatttgcca
     4321 agaggatttt tttattttaa aggaggaaaa gaagatggag tatttgattg aagttatgcc
     4381 gcaattatta gtaggagcac tcacaacatt gaaattattt ttatttacct tgattggctc
     4441 attaccatta gggattgttt tagcattagg attgtctttg cattttaagc cgctacgcta
     4501 cttgcttcaa acatatgtat gggttatgcg gggaacaccg ctgttgttgc aactgatttt
     4561 tattttttat gggttgccga cgattgggat cgtttttgat cgtttcgaag cagcactcat
     4621 tgcctttatc ttaaactatg cagcttattt tgcagagatc tttcgtggag ggatacaatc
     4681 gattcctcaa ggtcaatatg aagcagcgca agttttgcaa ttaagtccct ttcaaacggt
     4741 gacgaaaatc gtcatcccac aagtgacaaa gattgtttta ccttctgtag ggaatgaagt
     4801 tatcaacttg gtcaaagatt cttccttgat ctatatatta ggtttaggtg acgtaatgcg
     4861 tgctgggaaa atcgcgatgg aacgcgacgc gactttactg cctttgctag gcgtggcaat
     4921 catctatctt acattgactg gtattctaac aatcgtaatg aaacaagttg aaggaaaatt
     4981 aaattattac cgctaactga taggaggaag aaatatgatt gaattgaaga aagtgaacaa
     5041 agcatttggt gaaaaaaaaa taatcaaaga tttgaatcta atcattccag atgggaaaac
     5101 attagctatc gtaggtcctt ccggtggcgg taaaaccacg cttttacgta tcttggctgg
     5161 cttagaaagt tctgacagcg gagaatttta tttagacggt gtaccgttca acccattcga
     5221 gcttaaaatg aaagaacaag ttgtaggagt cgtattccaa gacttccagc tatttccaca
     5281 tctgaatatt tttgaaaaca ttaccttagc accaaaaatg gtattgaaac agacaaaaga
     5341 agaatacacc aaaaaagcag aagaattagc ggcttcatta gggattagtg atttattgaa
     5401 tatctatcct tatcagcttt ctggcggaca aaaacagcgg gtagcgattg ccagagcatt
     5461 ggctatgaat ccacgggtat tggcttatga tgaaccaaca agtgctttag atcctgaatt
     5521 acgccagcaa gtcgagcgtt tgatcctatc attgaaagaa gatggggtaa cccaaattat
     5581 tgtcacccat gatttagtat ttgcagaaaa tgtcggtgat caattactaa aagtttcccc
     5641 aattcattaa gaaaggagaa gatagagatg aaaaaaacca gttttctatt cgctttgatc
     5701 gcaggtcttc ttctttttgc aggctgttcg aacaaaaaaa cttcagcaga taattgggcg
     5761 actatcaacg aagagaaaaa aatcgttata ggtttagacg atacatttgt tcctatggga
     5821 tttagagata aagacgggaa gctcacagga tttgatattg atttagccaa agcagtcttt
     5881 gaacaatatg ggattacggt agactttcag cccattgact ggtcaatgaa ggaatttgaa
     5941 ctgaacaatg gaacgatcga tttgatatgg aacggctatt ccaaaacgcc ggcaagagaa
     6001 aagaaagtgc aatttacaaa accttatatg gaaaacgatc aagtgctgat cacacctaaa
     6061 gaatcaggaa tcacaaactt tggacaaatg aataataaga gattaggtgc gcaaaatggg
     6121 tcatctggtt atgatgtatt tacgaaacaa ccagaagtat taaaagagat agtcaaaaac
     6181 caagatgctg ttttgtatga tagttttaat gaagcattga tcgatctgaa aagcagacgg
     6241 gtcgatggtc tgctgatgga taaagtatac gcagactatt atttgaaaca aagaaacgaa
     6301 ctagaagact tcaacataac aaaaggttct tatgagagtg aggattttgc agttggtgca
     6361 cgcaagtcag atagtacatt agtgaaaaaa atcaatgaag ccctagatca actagagaaa
     6421 acaggtgaat tccaaaaaat atccgataaa tggtttggcg aagatgttac gccgagaaat
     6481 taacaaatag gggactgtga caaaagacgt gtcacagtcc ctttttccga ataaacagtg
     6541 ttctcctgcc aactccttgt gactcggagc tgaatggcag gctcacaacc tcttggtaaa
     6601 cggtgttcaa aagccagttt ttcggtatta agccaaattt atgcaaaaat gtagaaagcc
     6661 attttcacaa aatttttctt actactcgaa actaagcgac tttttcacaa cctcctttac
     6721 ataattttat tttgttgtgg aaggggtttc gtgttattct aaaagaggaa cgattgaagg
     6781 ttataggaaa ggaagagatg aatggaacac aaagaactta cctcatttcc aaaagatttt
     6841 ctgtggggct ctgcttctgc agcgtatcaa gtagaaggag cttggcaaga agatgggaaa
     6901 ggagaatcag tctgggatcg atttgtacgg atacctggaa agacatttaa aggaacgaac
     6961 ggtgatttgg cagtagacca ctatcatcgt tataaagaag atattgcttt aatgaaagaa
     7021 caaggtctga aagcttaccg cttctctgta gcttggacac ggatttttcc taatggacga
     7081 ggagaagtca atcaagctgg gctcgctttt tatgagagat tgatcgacga attgattgaa
     7141 aacgatattg aacctatgtt gactttatat cattgggatc ttccacaagc attgcaagat
     7201 gaatataatg gttgggaatc acgtcagatc attgaagatt tcactcatta tgcagaaaca
     7261 ttatttgagg cattccgcgg gaaagtccat tactggatta gtttgaatga acaaaatatc
     7321 ttcacttcat taggttattt gttagcagca catccgccag gtgtgacaga cccgaaacga
     7381 atgtatgaag ttaaccatat tgctaattta gcaaatgcat ctgtcatcaa taaatttcac
     7441 gagttagaaa tgcctggaaa aatcggacca agctttgcgt atacgccaaa ttatccaatt
     7501 gacagtaatc ctgaaaatgt tctggctgct gaaaatgcag aagacctgat ggccaattat
     7561 tggatggatg tctatatgtg gggaaaatat ccgattgctg ccatgaggtt cttagaagaa
     7621 aaaggatggg caccaacgat tgaagctggc gatgcagaat tgctagaatc tgctaaacca
     7681 gattttcttg ggatcaatta ctatcaaacg gcgacgaatg cattcaatcc attaaacgga
     7741 gttggtgctg gaaaaatgaa tacgacagga aaaaaaggtt catcagaaga aactggagtt
     7801 cctggaatgt ataaaaaagt tgagaatcca tttgtcgaac gaacaaattg ggactgggag
     7861 attgacccag aaggattaag gatcggactg cgtcgtatca caagccgtta ccgcatgccg
     7921 gtactgatta cggaaaatgg cttaggagag tatgacaagt tgacagaaga taaacaaatc
     7981 catgacgact atcgaatcaa ttacttacaa agccacgtca aagccatcaa agaagcaatt
     8041 tcggatggag cagaagtcct aggctattgc acctggtctt atacagattt gcttagctgg
     8101 ctgaacggtt atcaaaagcg atatggattt gtatatgttg atcaagacga aacacaagaa
     8161 ggatctttgg aacgatataa gaaagacagt tattactggt accaaaaact gattgaagaa
     8221 aatggagaga acctttagtt cacatactta aaacaagaag gtacggctgg atatggccgt
     8281 gccttttctt gataaaatca tttagaaatt aagaaaaact gtaaaataag ctgaaaaatg
     8341 aaagaaagcg tcagttcttt caaacaaaac tttagttccc ttactttttt ttgtataatg
     8401 aaacttgatg aaatgaggga taataaatgg cacaaaagaa acggcctact aaaaaaagga
     8461 aaaagacgaa aaaaacgaaa aagcaaaaac agcagcagga acaaatgctg acgattggtg
     8521 ttgggtttgc cttgatttta tttgctgtct tcggcttttt aaaattaggt tttttaggaa
     8581 tattgattgc aaacggcttt cggatcattg caggaaatac ttaccaaatc ctctgtcttt
     8641 tattagccgt attaggattt tggattgtca ttaagaatac agagttttca attggtaaaa
     8701 accgacgctg gtttggcggc atactctttt atttcggtat cttattattg ttacatgccc
     8761 atttatttgg caaactccat actggggaac caaatatcat ggggacgaca tgggatttgt
     8821 tagccagtga tataaaacaa agtcaagtag acaataacgt tggtggtggg atgattggag
     8881 caatccttta tcattttact tacttcttga ttgcacagcc tggaagttat ttagcagcag
     8941 tgctattact ggcaggagga gcattcctgt tcagtaatct ggaaggctat cagctgttaa
     9001 atggtatcca atcaattgga gaacgagtac aggaattatt ggaaggtgat cctgccaagc
     9061 aagctcgaaa gcaagcggca aaggaagaga gaatgaaaca gcgcgcagaa gcgaaagaag
     9121 caaggcgctt agctgcaaaa gaagctgcag aaaaagaagc tgcagaatat gagaagaaaa
     9181 aagcggtgag ccagcaaagg gaaaatactg ctgatgaatg gcaggaacca gaaaatacag
     9241 agccggagca gctaagtttt gttccaatcg acagttttca agaaaatatc catcctgcga
     9301 atctagagaa accagtacca gatacaccaa aacagaccaa tacagcagaa ggtttttcag
     9361 atgagttgcc agaggatgac ggtacctcat tagaatttga gattgaagca gaacaggaaa
     9421 atcaagacta tgaattaccg acagttgatt tgcttgattc tataccaact gtggatcaaa
     9481 gtgatgagta taaaaaaatt gaaaaaaata tcggcgtatt agaacaaact ttccaaagtt
     9541 tcggtgtcga tgccaaggtc gtcaaagcca gcttaggacc atccgtcaca aaattcgaag
     9601 tccagccggc tgtaggggta aaagtaagta aaattgtgaa cttaacagat gatatcgcgc
     9661 ttgctttagc ggcgaaagat gtccggatgg aagcaccgat tccaggtaaa tcactgattg
     9721 gtattgaagt accaaatgga aagatcagta tggtttcctt tagagaaatc atcgaagcac
     9781 aaccaaacca cccagataaa ttactagaag tacctttagg acgtgatgtt tctggacggg
     9841 tacaaacggc tgatctttcg aagatgcctc acttactcgt ggctggttcg actggtagtg
     9901 ggaagtcagt agcaattaat gggattatca caagtatatt aatgcgtgct aagccccatg
     9961 aagtaaaact gatgatgatc gatccgaaaa tggttgaatt gaatatgtac aacggcatac
    10021 ctcatctgtt gacgccggtc gtgacgaacc ctagaaaagc agcgcaagcc ttacaaaaag
    10081 tagtacaaga aatggaagaa cgatatgaaa aattcgcggc aaccggagta agaaatattt
    10141 ctggttacaa tgaatttgtt caacagaaaa acttggaaaa cggaacgaaa catccaacct
    10201 taccattcat cgtagtgatc gtagatgaat tagctgattt gatgatggta gccagcaatg
    10261 aagttgaaga tgcgattatt cgtttagcgc aaatggctcg ggcagcgggg attcatatga
    10321 tcctagctac tcaacgtcca agtgtggatg ttatcacagg aatcatcaaa gcaaatgtac
    10381 cttccagaat ggcatttgcg gtatcaagcg gtacagattc tcggacgatc attgattcta
    10441 atggggcaga aaagctctta gggcgaggag atatgctatt cttgccaatg ggtgagaata
    10501 aaccgatccg tgtgcaagga gcattcattt ctgaccacga agtagaacgg gtcgttcaat
    10561 ttgttacaga tcagcaagaa gctcattatg aagagaaaat gatgccgaca gatgaagttg
    10621 aaacgacagg tgctccagaa cagccacaag atgagctgtt tgaagaagca aaagcacttg
    10681 tcgttgaaat gcaaacggca agtatttccc ttctccaaag aagatttcgg atcggttaca
    10741 accgagcagc acgtttagta gatgaactgg aagctcatgg agttgttggc ccgtcagaag
    10801 gaagcaagcc tcggaaagta ttcattgagc aggaagaaac atcagaaacg ttgccggacg
    10861 ataatgacat gtaaaacttg tgtgatgaag ggttgaaaaa cgaataacca ataaaaagac
    10921 aaggcatgat gataccaaaa gaaaaaatgg tttttttcca tcttttctaa tacggtatga
    10981 tgtcttgtct ttttagtttt tgtgagatta aagttctatt cgatttattt gtgaagtatt
    11041 gcattaagga aatgaatcat gtatagtatg tagcgaaact ttgagaaaaa gagggaaaat
    11101 actttggaaa aacagtccat ttatggcttg acgaatgaag aattaatcaa ttggtttata
    11161 gaaaacggcg agaaaaaatt ccgagctgcc caagtttggg aatggttgta tcaaaaacgt
    11221 gtaagtaatt tcacagaaat gacgaatcta tcgaaacaat tgatcgaaaa attatcggag
    11281 cattttatca tcaatcctct aaaacagatg gtcgtccaag aagcttcgga tggtacagta
    11341 aaatatttgt ttgaactccc tgataaaaac atgattgaga ctgtactgat gagacaagaa
    11401 tatggcttgt cagtttgtgt gacgacacaa gtaggatgta atatcggctg tacgttttgt
    11461 gcaagcgggc tgctcaaaaa gaaccgtgat ctgactgctg gagaaattgt tgcacagatc
    11521 atgatggtcc aacattattt tgatgagcgc aatcttggcg aacgcgtttc acatgtcgtt
    11581 gtaatgggga tcggtgagcc atttgataat tacgacaatg taatggactt tttgcatatc
    11641 atcaatgatg ccaaaggatt ggcaattggt gctcggcaca ttacagtttc cactagtgga
    11701 ttagcacaca aaatcaagga attcgctaat aacggcttgc aagtcaatct ggctatttcc
    11761 ttgcacgcgc cgaataatga ggtgcgaaca tcgatcatgc ggatcaaccg aagtttccca
    11821 attgagaaat tgatggaagc tgtggatgag tatttagaga aaacaaaccg tcgaatcacg
    11881 tttgaatata tcatgttgaa tcaagtaaat gatagaccag agcatgcgca acaattagca
    11941 gatctattaa aagataagaa aaaattagca tatgtcaact tgattccata taatccagtc
    12001 agtgaacatg atcaatattc tcgcagtcca aaagctgatg tattgagatt ttatgatgta
    12061 ttgaagaaaa acggcgtaaa ctgtgtgata cgtaaagaac atggtacaga tattgatgca
    12121 gcttgcggac aattgcgaag caagcaaatg aaaaaaacag ttgccaaata atcgtatcct
    12181 actcgttttt tcaattacca taaaaggagc agttttctta attaaggaac tgttcaactt
    12241 aaataagaga aaagattcta tagcgaaagc tataaagctt tttttgacaa gaaaaaccct
    12301 catcaagcaa agaaatgtcc tcaatttgat gacagcctgc ttgatggggg ttttagcaat
    12361 tatttaactg attttcttat atccttgctg gctttcttgt gtagcatgat aagtttctac
    12421 gtcaagaatg gcctgtttaa atttttctcg ggtgatttca taaggcacat gtttaatatc
    12481 atttgttgcc atggctttat ctaagattgc ttctaaatcg gtcgtgacat tgagattcat
    12541 gtcggttaac gatactggaa gttggttctt tttcataaac acatagattt tatcaaacaa
    12601 atcgaactgc tgatccatca tcaataaggt cagtacacca taactgacag atgctccgtg
    12661 aaggtatccc tccatttttt ctagaacagt cgtaccgtaa tagaatgagt gtgccatagc
    12721 agaattatag ttattgttaa ctaaaacaga aaccaatccg gtagtaacaa tgatatccga
    12781 aacgacttgt tcaattgcat atgagggacg atcgtcggca ctatctttca atgcttgcgt
    12841 accataagtc aagagacgat caatgcacat ttttccgatt tggattccta atctatccgt
    12901 gtagcctaga tcatcgccac gagcagaaaa agtagattcg acttctttgg ataaagcatc
    12961 gccaatacct gcccataagt atttatcagg tgcttcggca ataattgctg tatcaatgaa
    13021 ggtgtgtaca ggtggttttg aaggaaagaa gagtccgtcc attacgcctt cttcgttata
    13081 gatgacacat accgcagtga cgggcgaaca gttcgaacca atagtgggaa aggtgaagac
    13141 tggtttagct agtttttcac caatgacttt tacagtatcg caagcacggc caccaccgac
    13201 tgcaaacagg acgtctgctt tttggacact ttcatgctgg atcaactgtt caatatttcc
    13261 ataagttgaa ttacccccgt accagagact ggcgacaacc tctatttcct gtgtcaaagc
    13321 tacttttatt ttgttttctg cctttgaaag tgcagtcttc cctccaatca gcactacttt
    13381 tgtcccatat tctttgacga ttccatttgc tttttcatac gcatctgttc caatggtata
    13441 atttggtaag aaaacacttt gactcatatt catttccttc tttcttcgtt gaaacgggtt
    13501 aaaattttaa agagtgatcg atctgactgc ggctgtagat ggagtagagg tgaacctaag
    13561 acaggataag tgatgaataa ggtggcatga acaccttgaa atcatcaata agtatcctaa
    13621 aaacgaacaa gtacaaaaac attgaaaacg acaataatga atttttgttc ctcttagtat
    13681 ttctaccgat tccctttgct tttttgtaat tatctaaaaa ttctaaaaat taagattatt
    13741 atatgaaaac aggttttatt tgtcaattca taattggttt tttttaaagc aaaagataat
    13801 ctatatcatg atgaacaaac agagtttttt cctccaattg atggctttcc tgatctttcc
    13861 tattttgaat aaagtgtttc tgtataattt tttattttat aagtaagata aataatgaaa
    13921 gaatagagat actgattggt agctaaagat ttttgagcga gaacatttcg ttttttcaaa
    13981 aggactgtta gaataagcaa gaacaagggg gaagacgtat gataatcagt gaatttgacc
    14041 gtaataatcc agtattgaaa gatcagcttt ctgatttact gagactgact tggccggaag
    14101 aatatggaga cagctcggca gaagaagtag aagaaatgat gaatccagaa cgaatcgcgg
    14161 tagcagcggt agaccaagat gagttagtag gatttattgg tgcaatccct caatacggta
    14221 tcacaggttg ggaattgcat ccattagttg tagaaagctc ccgacgaaag aaccaaatag
    14281 gtactcgatt agtcaattac ttagaaaaag aagtagcttc cagaggagga atcacgattt
    14341 atttaggtac ggatgattta gaccatggaa caacgttaag tcaaacggac ctgtatgagc
    14401 atacatttga taaagtggct tccatccaga accttcgtga acatccgtat gaattctatg
    14461 aaaaattagg ttataaaatc gtaggtgtct taccaaatgc aaatggctgg gacaaaccgg
    14521 atatttggat ggcaaaaacg attattcctc gaccaaattc tcaataataa aaagaggttg
    14581 tgacagaagt aatcagcttc aagaaataag aaggaattta cgaaaattac ttcttgaatt
    14641 tttgtgaaat tccaacttat ttccgaagaa gctacttttg gaacaccgtg taccagaggt
    14701 tgtgaaaaag tcgcttagtt tcgagtagta agaaaaattt tgtgaaaatg gctttctaca
    14761 tttttgcata aatttgg
//
LOCUS       DAZUJR010000074        14593 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.074, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000074 DAZUJR010000000
VERSION     DAZUJR010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14593
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.074"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(228..1115)
                     /locus_tag="ACG804_002183"
     CDS             complement(228..1115)
                     /locus_tag="ACG804_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4833104.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(1112..1981)
                     /locus_tag="ACG804_002184"
     CDS             complement(1112..1981)
                     /locus_tag="ACG804_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4833105.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(2118..3404)
                     /locus_tag="ACG804_002185"
     CDS             complement(2118..3404)
                     /locus_tag="ACG804_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFS4833106.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            3677..4255
                     /locus_tag="ACG804_002186"
     CDS             3677..4255
                     /locus_tag="ACG804_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFS4833107.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            4255..5184
                     /locus_tag="ACG804_002187"
     CDS             4255..5184
                     /locus_tag="ACG804_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4833108.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            5181..6917
                     /locus_tag="ACG804_002188"
     CDS             5181..6917
                     /locus_tag="ACG804_002188"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFS4833109.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(6980..7816)
                     /gene="pheA"
                     /locus_tag="ACG804_002189"
     CDS             complement(6980..7816)
                     /gene="pheA"
                     /locus_tag="ACG804_002189"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HFS4833110.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(7813..8322)
                     /locus_tag="ACG804_002190"
     CDS             complement(7813..8322)
                     /locus_tag="ACG804_002190"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HFS4833111.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(8315..9610)
                     /gene="aroA"
                     /locus_tag="ACG804_002191"
     CDS             complement(8315..9610)
                     /gene="aroA"
                     /locus_tag="ACG804_002191"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HFS4833112.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(9623..10714)
                     /locus_tag="ACG804_002192"
     CDS             complement(9623..10714)
                     /locus_tag="ACG804_002192"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HFS4833113.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(10731..11897)
                     /gene="aroC"
                     /locus_tag="ACG804_002193"
     CDS             complement(10731..11897)
                     /gene="aroC"
                     /locus_tag="ACG804_002193"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HFS4833114.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(11899..12963)
                     /gene="aroB"
                     /locus_tag="ACG804_002194"
     CDS             complement(11899..12963)
                     /gene="aroB"
                     /locus_tag="ACG804_002194"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HFS4833115.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(12996..14018)
                     /gene="aroF"
                     /locus_tag="ACG804_002195"
     CDS             complement(12996..14018)
                     /gene="aroF"
                     /locus_tag="ACG804_002195"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HFS4833116.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
BASE COUNT         4172 a         3160 c         2630 g         4631 t
ORIGIN      
        1 tgacaatcag gacagtcatc ggcaatatag cagcaatcac ttctttaaaa ttttttagca
       61 tgtatcctcc tcctttactc tttaagttta ccttaaaatg aaagagtttt cgagcacaaa
      121 cttaaaacgt tatcatttaa tttttctcaa cataaaataa cacacgtccc aaaagtatct
      181 ttttacttgg aaaaatgact ttgaaggaac gcgcttattg tgttttttta ttttacagag
      241 ccgatcattc cttgaacgaa ttgcttttgc aaaacaaaaa atacgatggc agttggtaaa
      301 gtagcgatga ctaatccagc catgatcatt ccatagtctg gtgtatagga agcacccata
      361 gcagataaaa caagcggaac cgtccgttta tcaggagatt gcaaagctac taagggccat
      421 aaataattgt tccagctact catgaatgtg atgattgcag ccgcggcata ggtattttta
      481 gccgtcggca tatacactct aaaaaaaata cttagttctt ttagaccgtc taatcgagcg
      541 gcttctacta gatcttttgg aaaagattta acattttgtc gaaagaagaa gatcaaaaaa
      601 gcagtgctaa cagatggcag gatgacaacc aagaaactgt tgattcccaa aaccgttccg
      661 ttcaattgtg aaaacattcg atataaaggg atcatcaatg ccgcaaaagg aaccatcatc
      721 gatagcagta gaatattgaa aattaggtct tttcgtttac tttgataaat ctcaaatcca
      781 tatcctgcca ttgacgaaat cagcaatgca aacacagtgg tcaccaaagc gatcatcgct
      841 gaattccaaa gggaacgagt aaaattcagc tcattggaaa acaaattttg aaaattgatg
      901 atcaagttac tgccaatctt tatttttccc gatgtgatat ccacgggtgt attcgtcatt
      961 cccaaaacca tccagacaaa agggaaaatg gaaataaatg ataggatgct taatgctgta
     1021 tactttaata ctgacccaat tgtcgaacga agttctaatg cttgtttttt gacgttgggg
     1081 cgttcgattg tttctttttc taccatattt ttcatcgact ttctcctcct actttcgttt
     1141 ggattatcga caatatcaca ataaaggaaa caataacaaa ggaaactgct gccgcatatc
     1201 caaaattagg cgtgaattta taactcaaat tatagatgta ttgagatagg gtggtcgttg
     1261 catttgctgg tcccccgcca gtaatatttt gtacttcatc aaaaagctgc aatgtcccga
     1321 tcgtcgaagt aatggaagta aacaaaatga ttggttttaa atttgggatc gtcactttga
     1381 taaactgctg ccatttagaa gcaccgtcaa tagatgctgc ttcataaatc tccgaatcaa
     1441 tattttgcat gcctgaaagg aaaaaaatca tattgtatcc agtccaacgc caagtgatcg
     1501 aaagaatgat cagaactctc gcccaaattg gatgagtcaa ccagccaatc ggtgtgtcaa
     1561 tcataccaat gcccaacaac aagttgttta caaggccaga ttgagaaaat agacttttca
     1621 tgatcagaga ataactgacc atcgaagtga tacatggaag aaagatagcg gttcgaaaca
     1681 accctttata tttcaacttt ttatcattta aaaggttgga aataaaaagt gctagaaaca
     1741 acatgatcgg tacttgtaca agtaaataca ggaatgtatt aaaaaaagct tttttaaaag
     1801 ttgcatctgt caacatccgc tgataattac ctaacccgtt aaatgtcata ttgacagggg
     1861 gaccactttg aaaagacgtg atcaaagcca aaaccatcgg aataaaaacc atgattgata
     1921 tcaaaatgac tggcaagatt aaaaaagcat gcccgttttt gaataaatct ttctgcttca
     1981 ttcttttccc tccaattcta tcattgatta tctacatgaa aagacaagaa agacaatatc
     2041 tgtaaggcag acgtgatctt ttttgtcttt tcgtttgtct gatgaaaaag cgaagaaatt
     2101 cactttttta ccaccgatca attagccaat tgtgcttcta cttgtttttg tgtatctgct
     2161 agtaccttgt ctgtctcttc tccattgatg attcgatgaa gagcttcagc tacgactgct
     2221 tcaattgcat aggtctcatg tccgtaattc acttctggta tttcagatgt ccatgttgaa
     2281 aaatcgtcaa agatcttttg accactgtaa aattcagaag cttcttgata agcttcttgt
     2341 tcattcgcgc taagcatcgt agatactagt ccgatttctt tcgcaagagt gcccatcagt
     2401 tcttcattcg aagcaaacgt tgcttctagg aaatctttcg ctgaatcttc tccagctact
     2461 cctttgatca cataccagcc agcgccgcca aggttagaag cttgcgcttt ttgcagattt
     2521 tctggaagtg caggtattgg tgcaatcttc cattttccag attggttttc tgctccttgg
     2581 atcgttgaag aataccaagc gccagttggg ctagaagcta ctgctcctga ttgtatcgca
     2641 gttactccag cattccagtc agaggtttgt tcgactagat cttctttcaa aagagtggca
     2701 aacaattcaa gaccatactt taaagatgca ttgtcttgga tcgtgactgt ctccccatct
     2761 tcagatgtat accattctcc tgcctgttgc ataatcatcc ttactcgacc aaggtcagaa
     2821 ggattgactt cagcgatttt ctttcccgtc ttttctttga catctcgcgc tacttgaata
     2881 tactcgtccc acttcagatt ctccatatcc tcttctgtat aacctgcttc tgccatcaga
     2941 tccgtacgat agaagtttgc tgttacgccc gaatcgaaag gaacaccgta tattttatct
     3001 cctactttgt ttaccgcaaa tttatacggt gcaaaatgat cttcctttac aatagcagac
     3061 aaattagcga atgcatctgg ataagaagtc aaatagcctt gtatcctata atcttcaatc
     3121 aagacgatat tgggcaatcc ttctgtattc ccgctcgcta aagcggtgtt cagtttctga
     3181 acgatatcat cctgagacat cgtaacaact tctatctctg tttcttcgtt ctcataaact
     3241 ttttttgctt cattcactgc tttgatattg aatgtctcat cccacgccca gacagtgact
     3301 ttttcttctt tgtctgctgt actactagca cttccgcatc ctgttaagaa acctgatgct
     3361 gccgctaaac aaacgactcc agcaattaac tttctgatgt tcatttttat ccgctccttt
     3421 tccatccatt agttgtttac gtttgctaca ttcatcatac caaaatttga aaacggtttc
     3481 tttattattc agatacttca aaaatttctc ctaaaataat aaaaaaatac aaatcaacta
     3541 tgacaaaagg aataatctta gcatctagac caaagatcga aatggtgagg tttctttaaa
     3601 ataaaaatat ccttgcattt tctcctagaa ataagtattt ttaaattaca agactattct
     3661 taaggcgggt aaaaaaatgc caatacgcgt aattcttatc gatgatgaac agacgatttt
     3721 agatggaatg aaacagttga tcaattggtc tgagcacggg tttcaattaa tagggacttt
     3781 ttccagtccg ctgaaagcgc ttgatttttc tttggtacat gcaatcgata tcgtggtcac
     3841 agatgtaatg atgcctgaat taaatggaat cgaattatcg cggctattaa aacagcaaca
     3901 acctgaaaca cagatcctta tcctctctag ctatgatgaa tttgatatgg ttaaagattc
     3961 ttttaaagaa ggcgtcgctg attatctttt aaagcctcga ttgagtcctg atttttttct
     4021 aaattcctta actgccgttt cacaaaaaat caaaaaaaag cccaacaaaa gcccaatcac
     4081 caatcgttat gagcagatct gcgagaatct ttcacagcag attgctggac aaactcgtcc
     4141 attgcttgac cctcttcttt ttgaacacac cttgtttttc tgttatatac cgaaaaacgg
     4201 ccattcagtt caaaacaagg ctctaaacaa aaacagtcga tcacccattc attgatggat
     4261 agcgacgatt cgtttactat ttatcctgtt tctacctttt cggaagaatc cggctatgta
     4321 atcaatactg attccaaaga tacacttagg aagtttgttc aaaagtttcg tcaagaagtt
     4381 tttccaggtg atttttttgt tgtttctgat tcttttgcaa tccaagatat caatgaaata
     4441 ttccaagaga tcagaaattg caccaaagga caacgtttct atcataaggg aaagaacctt
     4501 gcttatcagc atgaacttct tccgttatta accaaccacg agcagcaagc aagtagttat
     4561 ttaacaaaaa tcgttcataa agactacgct ttagctgtca aagaacttga gaatttcttc
     4621 acgacgatat tggaacagcc tattgatcca gcttatttga aacatgaggc aatcaatcgt
     4681 ttctatgcat tactcaacgc tttggctgac gagcatgttg ggaatgaaga actttctttg
     4741 ctcaagatcg cccttccttc tttattagcc gatgctgagt atttcgaaga tttttctatt
     4801 cttgtcaaag aaacacttga gaaactcacc cacttttctg caaatgcaaa aaaagacaat
     4861 ttcgatatct tgactttgat ctacgagttc gtccaggaaa attatgagaa agaaatcaat
     4921 ttacaacttt tatccgaaaa atatcatttt tcatatagct atctctcagc catctttact
     4981 gaaaaatttg gtatcaactt ttcaaaatat ctaaaaaaag tccgtatcag taaagccaag
     5041 ctctttttga cggaaacacg gcttactttg acggaaatct gtgagaaagt cggctatacc
     5101 gaactgggtt atttctccag agtttttaaa gaagagacag gaatgacacc ttctcaatac
     5161 cgtaaaggaa cttttgtaaa atgagaaaaa aaatcaaaga gcatgaactc tttgccaaac
     5221 ttctgttcat tttgttcatc ggtctttttc tgcaagccat cgtcatttct ttgtttattt
     5281 atcatcgatc aagggatgcc tatatccagc tgttcaatca atcgaatgat gtggtactaa
     5341 aaaagattca atctgaattt gaaagtttga atgatacaat cgagaataca ttagccgctt
     5401 ttgattctaa tccagctgtc aaaagctatt tttccaatga tccagcccaa catatggaac
     5461 agcttcagca actaagaaca atccaaaaaa tgaatgactc tctttcaaaa atccatccaa
     5521 tgatcgatta cgatgtattg atctttggag aaaatggaag aacttttgtc ggaaacgaca
     5581 tgctcactgc cgtatctgcc gattcttttt ttcaatctgc gattgctcag agagtgaatg
     5641 aacgtgctgc tgatacacaa atgctttttg cacaccacgg attgactctt cgcgataaga
     5701 aagcacccag cgtcttcttt gtcaaaaaac tgaaaaatac attgaatcac gtttacggat
     5761 atgctgtttt atcgatctca tccaagcaac tagcgaatct ttttcaatct gtagtaaatc
     5821 ctgagatatc gaagatctcc ttcatgaacg aagaacagac gatcatcgca tcaaatgaag
     5881 aaaatacaat tgggagccga tcaatgattt tcaaaaaact aacagtaggt gaaacaacga
     5941 tttcaaatgg acagcagttg acccgtcttc ctctgtaccg ccaggattgt acattactca
     6001 gtcaagtcga tcttcattct ttatctaacc aaatgggcgt gatttttccg attattttgt
     6061 ataatatcgt gacacttgct tttgctggct cattggtatt tatgtatttg gatcgacaca
     6121 caaaatcgat ctaccgcttg attgattcgc taaaacggct agaggaagat ggcttaaaag
     6181 ctactgttcc tgtacaagga agccatgaag tccaattgct agggaatacg atcaatcaat
     6241 tgctaagtaa tgctcagcat cattatgaac agacgatcca agacgaaaag aagaaacgtt
     6301 cgcttgaaat ccaaactatg caagcacaga tacagcccca ttttatttat aatacgctga
     6361 ctagcttgaa atttttgatt tggcagaaaa aaacagatga agcagttcaa ggaatcgaca
     6421 gtttcattac tttactaaga agtacgattg ggaaaaaaga agaagtgatt ccagtcaagg
     6481 aagaaatcaa aagcgtacaa agttacatcg atcttttgag tatgcgatat ggcgaaagaa
     6541 tctcggctaa aataatgatt cctgatgaac tgcagtcatt atctatgccg aatatgatcc
     6601 ttcaaccaat tatcgaaaac gcctatcttc atgcttttca caataaaacg caaggattca
     6661 tcacggtgta cggcaaaaca aaaaatcagc ttcttttatt cgaagtgatt gataacggcg
     6721 atggcttcga tactgaaaat accaaacaaa aaaatgatca tttttcagga atcggcatca
     6781 gccatgtaga tgagcggata cgcctaatgt atggcgatgc atatggctta acgatccaat
     6841 cagtgattgg gacaggaacg actgtaacga tttgtctacc gcttcttcct aaaaatcaat
     6901 cagaatatca aaaataaaga atagccaagc gctgattttt ttattttaag ttaaataaat
     6961 caatcagtat tcttgacttt catctacgcg tctcttctac tgtcagcact ggataacagc
     7021 ccaatatttg actttctcct ccgagcatct tgatttcttg gagcgcattc tctactaatg
     7081 tcattggacg gtccaacaac aaatcgatca cgaaaaaata ttctcccaag ctagttttca
     7141 atggtcggga ttcaatctta cttaagttga tttcccgcca gccaaaagct gccagcattt
     7201 tatgaagcat ccctggccga ttagcaggta gtgtcaagat gacactcatt tttactggag
     7261 ctgactgctg gctggtcatc tttcggtcac cgacgatcca aaaacgtgtc tggttcaact
     7321 cattatcttg gatattctca gctaagatct ccaatccaac atgctgtgct gtttctaatg
     7381 aagcaatcgc tgctgcgtct tctttcggat gttctgctac atacattgct gcagcagttg
     7441 ttgattctgt tgctactaaa ggaacattag gataatgcgt ttctaaaaac tgttgtgatt
     7501 gtgctagtgc ttgtggatgt gaaaggattt ttgtaatctt tgttgctgga ttgcctaaaa
     7561 gctgctgctt gataggaaga acgatttcac ttttaacttc gacttctgga tgtttggaaa
     7621 gaagatcgat tgtgtgatga acagctcctt ccaatgaatt ctctacagga acgacagcca
     7681 gatcgacttg tttgcgaaac aaagcgcgca aacaaacagg gatggaagca tacgcagtca
     7741 attgttctgt aggaaatagc tgacaagccg cctgataagt gaatgaactt tctggcccta
     7801 gatagctgac gttcatatgc ttttgatcct ttctataatg gtatcgatga tcttttctgg
     7861 tgtttgattg gtcgtgttga ttcgatgtgt cgcactttct tcataccaag aaagtcgttg
     7921 tgccaataat gcttttattt cttctcttgt ttttccaaga gctaaaggtc gaatagacgt
     7981 ttcatcttgt tggatacgat caactagaca gtccgcttct gcctctaagt aaagaacaat
     8041 cggctgtgtt tttaaaaaac gccgattttc tgcactttgg acaatccctc caccagtcgc
     8101 gataattttg tcttcatttg acagctttct taaaatatct gactccactt ttcgaaagct
     8161 tttttcaccg taatagtgaa aatattcggc aatcgacaat tggatatgtt cctcaatctt
     8221 tgtatctaaa tctacatact ctttttgtaa acattgagct aaccctttac cgattgttgt
     8281 ttttccagcg cccatgaaac caatcagcaa aatgctagcc atgagcttct cctcctgaca
     8341 caagttctgc taaatcgtca aaaaatgccg gataagagat tgaaacagct tcagctcctt
     8401 ctagttcgca aggtccatca gctatcaaag cagctacttg cagcatcata ccgattcgat
     8461 gatcgcctct gctggacact tttgcgccat gcagaggtgt cggcccatgg atgatcagac
     8521 cgtctgctgt cgcttttatc tttgctccca ttttctgtaa ttcttctgcc accgcatcaa
     8581 ttctgttggt ttcttttact tttaattctt ctgcgtcttt gatgatcgtg attccttctg
     8641 cttgagtagc cactaaagct agaatgggca attcatcaat cagacgcgga atgatttctc
     8701 caccaatcgt tgctttcttc aaatgactcg tcttgacact taaatcagcc gattggttct
     8761 gttcattgtg attcgtctgg gtaatcgctg cgcccatctc ctccaacaca tctaagatac
     8821 cagttcttgt tggattgacc ccgacatttt ttaacaacag ttggctttcc ggaacaagaa
     8881 gtcctgctgc tagaaagaaa gcagctgatg aaatatcacc tggaacagtt atctgttgac
     8941 cagttaattt ttgcggtccg gtcactatga tcgttttatc ttccactgtg atccttccgc
     9001 caaattgacg aatcatttct tccgtatggt tacgggaacg ttctttttca acgattacgg
     9061 atgtgccttc tgcttgtaat gccgcaaaca gcaaagcaga tttgacttgc gcactggcta
     9121 caggcatatt gtatcggata ggtgataaag agcgggttcc tgtcacagtg attggtagat
     9181 actggtcatt ttcttctcct tgcaagtcag cgcccatctc gcgtaaaggt tccatcactc
     9241 gccccattgg acgtttagac aacgaagcat ccccgaacag agtagtcgta aaaggctgtc
     9301 cagccaaaat acccatcaat aaacgtatgg tcgtaccgga gtttcccatg tcaattgatt
     9361 cggttggttg gacaaatgag tggctaccgc gaccatgaat cttgatcacc tcttcctctt
     9421 cttcgatctc gacacctaat tgttggaagg catgtaaagt actcagacaa tcttctgcgc
     9481 gcaaaaaatt ttgtatagtc gtcgttcctt cagcaattgc tccaaacatg atgctgcgat
     9541 gggaaattga tttatctgct ggtatcctaa cagtccctct taatccatgt atttgttgta
     9601 ataattgcat ttatccagcc tcctatttga tccagcaatg ataactggta ttagacataa
     9661 tgattctttt tgcttgtaac aaatcctgtt ggtttttaaa actgatttgc agtattccta
     9721 aaatatcttc cctggtctct tggatcttca aattaatcaa agaaactccc gcttttccga
     9781 tcagtccagt tacttctgca ataacgccag gttcatctgg cacatcgata aataaatcaa
     9841 aaaaggcagg aatcgcgcct tgcttatgga caggcaactg gtctcgactt tcttttgccc
     9901 gattgaaaaa agaaaagatt tccgattggt tctcagtcat gatccattct gctatttgtg
     9961 tcatttcttg ttgccaatct gccaatcgtt ccaataatat ctgcttattg ctcaacaaaa
    10021 tatctgtcca catgacagga tctgaggaag cgatcctagt gatatctcga aagcctcctg
    10081 ctgccagttg tttggctcgc ggatactctt gattgaattg ttctgcctga ttgactaagc
    10141 cagctgccag aatatgtgga aaatgactta gcattcctgt tatacggtca tgttctcttg
    10201 ctgtaagagt tacatatttt gctttggttc cgcaaaatag ttcttgcagt ttttcaacat
    10261 cttttttcgt cttttccaaa ggtgtaaaga tgtaataggc attttcaaat agtttagcat
    10321 ctgctgcctg tatacctgat ttatgagaac cagccattgg atgtccaccg acaaaccgaa
    10381 gatttttctg ctcagcggat gtcacgactt gctgcttcgt actgctgaca tccgtaatga
    10441 tgacgtgatc agacaagttg attctttcaa ggacatcaag ataagctaag gttgtacgga
    10501 cgggaacggc taataagata acgtctgctt gttctgcacc tgtttcaaaa tcacttgcaa
    10561 cgtaatcaac gatctgctgt tctactgctt gctcacgggt ttttgactga ctatcccaac
    10621 caactactat cagttctgga ttggtctgac gaatacaaag tgccatagaa gcaccaatca
    10681 gtccaagccc cacgataaaa acatgttgtg ccatcttatt tgcccccttt ttagtaatgt
    10741 ttcaagtagt cacggtactc cttcactgca gctttcaact caacaagcga atcacttggg
    10801 aattttgaca atagctctgt cgctaccaca gtggctacaa cattttccgc aacgacgcta
    10861 gctgcaggaa ctgctgtact atccgaacgt tctacacttg ctttgtaagg ttcttttgta
    10921 tcgatatcaa cactttgaag tggcttgtac aatgtaggaa tgggtttcat gaccccgcga
    10981 atgacaagtg gttcgccatt ggtcattccg ccttcgaagc cgcctagatt attggtacgt
    11041 cggaaatagc ctctttcttc ttcccatagg atctcatcca tcacttctga gcctggtaat
    11101 gaaccagaag tgaatccgac cccaaattct acgcctttaa aggcattgat actaaccaca
    11161 gcttgtgcga ttttggcatc tagcttcgtg tcccattgta cgtagcttcc taatccagct
    11221 ggaacgcctc caacgagcac ttctacaatt cctccgatcg tatctccatt tttctttgtc
    11281 tgatcgatca aatcttttat tctttgctca actgctggat caacaactcg tacttctgac
    11341 gcttcagaaa tttctttgat ttcttgaatc gagatatttc caggtatttc tgcttggatt
    11401 ccaccaagac aaatcacgtg tcctgctacg atgatgtcaa gttcttccag aattttcttg
    11461 gcaattgcgc cgattgctac acgcatggtc gtctctcttg cagaggaccg ttcaagcaca
    11521 ttccgaagat ctcgatgatg gtatttcata ccgcctacca aatccgcgtg tcctggacgc
    11581 ggacgtgcaa ctcgccgcag tgattggtct ttttcaggca cttctgctac agacatgaca
    11641 gttgtccaat ttttccaatc tttattttct accactaaag tgacaggtga accaattgtt
    11701 ttgccgtgac ggatgccaga cgtgatccga acacgatctt tttcgatctt catccttcct
    11761 cctctgccgt aaccagcttg tctgcgagcg agttcgtgat tgatttcttc ttctgacaga
    11821 ggtaatcctg ctggtagtcc ttcaataatg gctgttaatt ctggtccatg ggattctccc
    11881 gcagtcatat aacgcatctt acagtcctcc taagtaatct ttgaatgtct ctgtgggaac
    11941 aggaacgatt tttgcttgcc caatcttttc tagcaagatg atattcaatt ggcttcctct
    12001 tgctttctta tcatgggtta tcgcgtggaa taattcatct ggatgactta gatcgtacgt
    12061 aatcggcaga tggaattttt gaagtatcct ttctaaagca gctgtcgatc cagttggaga
    12121 caagccgatt ttttctgcat gagaagtgat ggctaccatt ccaatagcta ctccttctcc
    12181 atgactgact accccatatc ctgctgtatt ttcaattgca tggccaattg tatgaccaaa
    12241 atttaaaata agtcgatttc cttggtcaaa gacatcttct tccactactt ttcgtttgat
    12301 ttccaacgta gcagtaatga ttggaacagc atgttccaga agatcttttt cgtctttcag
    12361 ctcgttcagc tgtttccaaa gcgttgcatc tgctatagct gctgatttga tgatttcagc
    12421 gattccttct cgtaaacgac gtaccggcaa agtttttaga acctcaggat caatcaatac
    12481 accagctggc tggctaaatg ttccgacaag gtttttcgct ttgtttgtat tgactgctgt
    12541 cttcccgcca atactagaat ctacttgtgc aagtagcgta gtcggaattt gaacgaaatg
    12601 gatcccacgc atgaacgtcg aggccacgaa tgctgctaga tcacccacca ttcctccacc
    12661 aagtgcaagt atcccatcgc tgcgggtaaa atcattatct gctaaaaaat cgtataactc
    12721 agctgcttgt tctaaagatt tactggtctc acccgccggt acgattgaaa ggactggttc
    12781 aaaattagct tgtctcaatt ggaacatgat tttttctgca tatagtggag caacgtttgt
    12841 atcagtgatc acagctactt tttgaggtct ccaaatcgtt tgaagccatg atccagcctg
    12901 ttctagtgcg cctttttcaa tatgaatatc gtatttttgg ttatcaacat gtacagtaag
    12961 cattcgtttc acttctttct tttaaaaagc tggaattaat cgagtgtctg aatcttttcc
    13021 attgcttctt tcatgatcgc aacttctttc atcatgcgtg agtaagtctt ttcattcaac
    13081 gattggggac cgtctgacca agcatttgca ggatcaggat ggatctctac gatcatgcca
    13141 tctgctccgc ttgccacacc cgcacgagcc attggtggta caagttccca aattcctgta
    13201 ccatgacttg gatcaacaat cacagggaaa tgagttaatt ttttcatcaa tgggacagca
    13261 cttaaatcaa acgtattacg tgtcgctgtt tcgtaagtcc gaatcccacg ttcgataaaa
    13321 atgacaggag atttgtcttc gactgcaatg tattctgcag cattaagcca ttcattgatc
    13381 gtaccggaaa ttccacgttt caatccaaca ggtttacctg ttttaccgac agcagatagc
    13441 agtttaaaat tttgcatatt acgtgcgcca atctgtagga tatcgctgta ctcagccacc
    13501 atatcgatat gcccttcatc catcacttca gtaatcactt tcattccaaa ttcatcagcc
    13561 gcttgacgga tgtatttcaa tccttcttct tctaaacctt ggaaagcata tggagaagta
    13621 cgtggtttga aggcaccacc tcgcagaatt tttgcgcccc cggctttggc cattcgcgca
    13681 cattctctga tttggtctaa tccttcgata gaacaaggac cagccatcgt cacgaaactg
    13741 ccgtcaccaa tttttactcc gtctacatcc acgactgtat tgccaggatg gaattctcga
    13801 gaagtcaatt tgtatgtgtt taaaatacgc acagcatttt ctactccttc atagcgtgta
    13861 aatgctcctt cttgtaaact tcgcgtatca ccttttagtc caatcactac tcgttctgtt
    13921 ccttgatcga ttgagacttt gaatccttct ttttcgatat gatcgacgac tttttttatt
    13981 tgttcttccg ttgcttcttt tttcataatt actatcattg tttttcccgc tttcttttgt
    14041 ttacttatct atcttggctg attttctcta ctttttcaag gtggttttac attaattcct
    14101 actaaatgac cgtgtcctgt tgttctcatt ttcgctcctt ctttcctact tatgacccag
    14161 ataatcaaca aaaaaagatg tccctgtagg aaattgcctc tacagtgaac atcttcaacg
    14221 agccttaaaa agcgctgcaa aaatataaaa tagccactat agatgaattt ctctacgtgg
    14281 ctgtaagtcg tgtttaaaaa tctttagcca tcatagatac aaacctggtt tgtttgtacc
    14341 cacgaagtca tgaatacaaa cctatctaaa atagctaaag taatacgtat tcagttttgt
    14401 aagttttcta gatttcataa aaaatcgctc caaactgatg taagaattgt acctagtata
    14461 gacataaaaa aatcgactgt caatcatttt tatgaaactt tttttaattt tctgatagtt
    14521 aactttgttt ttcagaaaaa taacaattgg ttttattgaa gaaaatagtc atgaacaaaa
    14581 gtatctgaga act
//
LOCUS       DAZUJR010000075        13847 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.075, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000075 DAZUJR010000000
VERSION     DAZUJR010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13847
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.075"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(325..1494)
                     /locus_tag="ACG804_002196"
     CDS             complement(325..1494)
                     /locus_tag="ACG804_002196"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFS4833117.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            1698..2873
                     /gene="mltG"
                     /locus_tag="ACG804_002197"
     CDS             1698..2873
                     /gene="mltG"
                     /locus_tag="ACG804_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HFS4833118.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            3009..3488
                     /gene="greA"
                     /locus_tag="ACG804_002198"
     CDS             3009..3488
                     /gene="greA"
                     /locus_tag="ACG804_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HFS4833119.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            3657..4388
                     /gene="liaF"
                     /locus_tag="ACG804_002199"
     CDS             3657..4388
                     /gene="liaF"
                     /locus_tag="ACG804_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HFS4833120.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            4385..5452
                     /gene="liaS"
                     /locus_tag="ACG804_002200"
     CDS             4385..5452
                     /gene="liaS"
                     /locus_tag="ACG804_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     LiaS"
                     /protein_id="HFS4833121.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            5459..6091
                     /locus_tag="ACG804_002201"
     CDS             5459..6091
                     /locus_tag="ACG804_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFS4833122.1"
                     /translation="MIKVLLVDDHEMVRLGVSFYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            6231..6896
                     /locus_tag="ACG804_002202"
     CDS             6231..6896
                     /locus_tag="ACG804_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HFS4833123.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            6924..7217
                     /locus_tag="ACG804_002203"
     CDS             6924..7217
                     /locus_tag="ACG804_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HesB/YadR/YfhF family protein"
                     /protein_id="HFS4833124.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(7285..8232)
                     /locus_tag="ACG804_002204"
     CDS             complement(7285..8232)
                     /locus_tag="ACG804_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HFS4833125.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(8410..9213)
                     /locus_tag="ACG804_002205"
     CDS             complement(8410..9213)
                     /locus_tag="ACG804_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HFS4833126.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            9359..10273
                     /locus_tag="ACG804_002206"
     CDS             9359..10273
                     /locus_tag="ACG804_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFS4833127.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            10321..10791
                     /locus_tag="ACG804_002207"
     CDS             10321..10791
                     /locus_tag="ACG804_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HFS4833128.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            10876..11484
                     /locus_tag="ACG804_002208"
     CDS             10876..11484
                     /locus_tag="ACG804_002208"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HFS4833129.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            11618..11818
                     /locus_tag="ACG804_002209"
     CDS             11618..11818
                     /locus_tag="ACG804_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFS4833130.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            12572..13798
                     /locus_tag="ACG804_002210"
     CDS             12572..13798
                     /locus_tag="ACG804_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFS4833131.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
BASE COUNT         4705 a         2114 c         2795 g         4233 t
ORIGIN      
        1 gctaattgtt cttctttttt attgcataaa attaaaaata agaacaagcc atgaatgatt
       61 tgctagcaca tattttagca atctaaagat actattttag atttaatagg ccctttgtca
      121 aataatgttg gtaaagagaa atcttagaat aatttggaca gaacagaaag aagaacacct
      181 ctttctgttc tgtttatttg gaattaaagt ctgtagcaaa aattgatttt tagatttgtc
      241 ccacactctt tcctacgttt agtcgagtac tttttttaag caaatgctat tcaaagaagt
      301 agtatttgct atcttttcat catatcagct atttgccaac ttagtagttc cttccatcag
      361 gtcatagatt tggtttctta gatcagcagt aggcagtttg atagttttgt cagcttttat
      421 attgctttcc atgatgatag catcctgtga atctttgcta aatatagcag atgtatcaaa
      481 agagtcgata tttccttgcg acaggatata attatctccg ctatataccc caccactata
      541 tggatgtcca ttcgcatttt cacgccataa tgagaagagt aagtctttgg aaactagttt
      601 tccagataaa acttgtgtaa acagcgtatt taaatcatag acggacatac tgatattacc
      661 agtccctaat tcgttatgga tctctgtttc agattctgtc agtggtttaa agtaatcatc
      721 ctctttagac atttgatagg atagtgcatg attggatgaa tttttgactt ggtcataaaa
      781 ttttgtatgc tgtaatccta aaggttcgat gatatcatcg gtcaataatt tttcatacgg
      841 ttgatttgtt aatttgatca aaattccagt caatatggta aagttcaatg aatcataatg
      901 agaggtctga taatctgtaa attttaagtg ctgaatcgca aattgaacga cttcttcatc
      961 agtcatcggt atggttggag aagcagttcg gtgcaagcct gagcgcatat acagcaagtc
     1021 acggatagta atttgctggc tgccagcaat ttgtggatag aattgagcca gcttagtatc
     1081 taaagaaagg tgcccacgct cgacttgttt taaaatcaaa agagtagtca atgctttttg
     1141 aaccgaacca atctgataat aaagagaagg atcatttggt tgttgcgtga gtttattcgc
     1201 atagccatag cctttttcca tgatgatgcg attatttttc tttacgtaaa ttgagccaat
     1261 ataatcattt tttcttaata gttgatcgat tttttcaacg agctgttgtt cattggtagt
     1321 cagtatcaac tttttttgag ctgattgagc atgggcaact atctgagagt gttcattatt
     1381 gtaaaattgc catccaagaa tagttcctgt agagaacgca ctaaggctaa acaacacgac
     1441 aacgatcatt aaaaatgaat attttctttt tttagcatgt tttccttttt tcataatagt
     1501 ttatttagtc tcctttcttt tttacagaaa gaataaagct aaaatagctt gtatcttgat
     1561 aacatttatt ttaatcttat agtaatggat ttactactta catttttgat agaatattta
     1621 aataaaatca ttcacgccaa ttcaaatatc atgtataatg aataaagtta cgaacttgat
     1681 agtaaggagg agttgttttg tcaggaaaca aacaacaccc aagtaaagat aaaaaagaag
     1741 ccagtaaggc agctacagca gatataatcg acaagcggag aaatctgcgt aaaaaagaag
     1801 ataagattgt gaggaagatc attttagtga ttgctcttac attattgatt attggcggat
     1861 ttcttggatt taccgtgtat cgttatgtag atagcgggtt gaagccttta gataaatcag
     1921 atgaccaatt agtccaagtc gagatcccga gtggctcttc taacaagcag attggtgaga
     1981 ttttggagaa ggacaatatt attaaaagcg ggattgtttt caattattat acaaaattta
     2041 aaaatttaac tggctttcaa gctggctatt atcagttagc gcctaatatg actcttgacg
     2101 agattggcaa acagttgcaa gaaggcggta cttctgagcc aacaaaagtt gcagatggga
     2161 aaattgccat tccagaaggg tacgatatcg atcagattgc tgaacgggta gcgaaggtaa
     2221 ctggtaaaga caagaaagaa tttttagatt tagtgaatga tgagactttc tttaacgagt
     2281 tgcaccaaaa attcccagaa ctgttggaaa gtgcatctaa agctgagaac acaaaatacc
     2341 gtttggaagg ttacttattc ccagccacat atgattatta cacgagtact tcgcttaagg
     2401 atctagtgat tgaaatggtg aacaagacga atacggtcat gcaaaactat tattcagcta
     2461 tcaagcagaa aaatttgact gtacaagaag ttttaactct agcttctcta gttgaaaaag
     2521 aaggcgtaaa agaaaatgat cgtaaaaaca ttgcacaagt cttctttaac cgaatcaaag
     2581 caaatatgcc acttcagtca gatatctctg ttttatacgc attaggtgaa cacaaagaat
     2641 tagtgacgta tgaagataca gctgtagatt caccatataa tttgtatacc aataccggct
     2701 atggacctgg accttttgac aatccaagcg aagaggcaat caaggcagta ttagaaccag
     2761 cagaaaatga ctattattat ttcgtagcag atacgagcac tggaaatgtt tatttcgcta
     2821 aaacttatga agaacatatg gaattagtgg aaaaatatgt aaataattct tagaaaaaca
     2881 ggctctagac attgatcatt tttagaaaaa catttacatt tgaagaaaag cgtggtaatc
     2941 ttttttggac tatattcctc aaaagattac cttttgcggt attttatcga aaaaaggaga
     3001 cgttacacat ggtagagaaa gtttatccaa tgactctaga aggtaaagaa aaattagaaa
     3061 aagaattaga agaactaaaa acagtcaaac gcggagaaat cattgaacga atcaaaattg
     3121 cccgcggttt cggagatctt tccgaaaact ctgaatatga atcagcgaaa gatgaacaag
     3181 catttgttga aggaagaatc acaacaattg aaaatatgat tcgttttgct caaatcatcg
     3241 ataacgacgg tgtagatgca gatgaggtat caattggtaa aacagttaca ttcatcgaac
     3301 taccagatgg agaagaagaa gagtacacga ttgtcggaag cgctgaagca gatccgtttt
     3361 ctggcaaaat ttccaatgat tctcctattg cgcaagcatt gattggcaaa cgtaaaaatg
     3421 atgaagtaac tattgctact ccaggtggcg atatgttagt taaaatcgtc aaagtagaac
     3481 aagcgtagtc tgactgaaag atctagagag ttcatcttac tgatgataca ctctagatct
     3541 ttttctcttt gtgtatttta gatttcaaca aacgatctta catctaaagt cctatagcca
     3601 acagttaaaa aaataggtat gatgaaatga gaatgtgtca ggagggagaa agagcgatga
     3661 atagttcttg gcgttttttt gtggtagttg aagcactact gctgttattt gctgtttggc
     3721 aaatcgtaaa caatactgga cttttgcttt tagtgatatt cggtattttc aatatatatc
     3781 tagctatgcg caaacatcct cgtactaaat ttcaaaattt tcaattgata ttaggaagtt
     3841 tggtcatttt ttttagctta gtcaacagtc ctgctttatg gatgatggct gtatttgccg
     3901 ttttatttat tggtctgaaa ggtgtagaga tttcagggat agatttaacc aaaaatgctt
     3961 tttggcgaaa gaaacagatc atgatgatcc aaacagagca attaaaaaca cataataatg
     4021 agcggaaaag acagcaatta ttcggtaacc aacgtattgg aaacgacgtc tatgaatggg
     4081 acgatatcaa catcgccgtc atttctggtg atactatcat agatttgggc aatacgcttt
     4141 tgccaaaaga tgataatatt gtgattgtaa gaaaagggat aggcagaaca cggatcttag
     4201 tacctttggg cgtagccatc cgattagagc atgcgacatt agtaggaaat gtcttgtttg
     4261 aagaagagca attttctttg aaaaatgaac aaatcaaaat ctacagcagt gattatgatg
     4321 aaaaccctcg tagattgaag attattacta ataccttgat tggagatgtc gaggtgatac
     4381 gaatatgatg ggaaaaatat ccagagcgat gctagctgtt tattcgggga ttgcggcttt
     4441 ccttattatt ctattttcac ttttcactta tttttatgcc agcaatcaaa gtcattggtg
     4501 gggagaatta ctgcgtgcac gtttattata tgttccgctt atcttccatt tgttagccat
     4561 ttccttaggt gtaggattaa ttgtctttct attattatca cttattcaaa agacaaaata
     4621 cgggaaaatc gaagaaaagc tgcgtgcact ttcttctggc aattatgaat ccaaattgtt
     4681 gcttcttccg atcccaagtg catcggacga tttatacatc aaagatattg ataaggaaat
     4741 cactaagata aaagaaaaaa tgattgaagt atctagtgaa ttacaaattg taacgagccg
     4801 tccccaatat gtagatggac aaaccaaaga agaaatttta gaattagaaa gacatcgatt
     4861 agcccgtgag ctgcatgatt cagtttcgca acaattgttt gcagcaatga tgatgatgtc
     4921 ggcattgacg gagcaagcag aaaaaagcga gacaccagaa atgtttcgca agcagttgaa
     4981 aatggtagca gagatcatca acgcttccca gtctgagatg cgtgcgctgc ttcttcatct
     5041 acgtccagtc aatttagaag agaaaagttt aaagcaaggt atcgagcagt tattgaagga
     5101 attgcaaaat aaaatccaga tttcgctgaa atgggatgta gaagatgtaa aactatctag
     5161 ttccattgag gatcacttgt tccgaatcgt tcaagaattg ttatcaaata cattaagaca
     5221 tgctaaagcc aatgaattag aggtatattt gcacaaaata gacaataatc ttttgttacg
     5281 tattattgac gacggaacag ggtttaatat gaatgaaacg aaaacgggaa gttatggatt
     5341 gaacaatatc aaagaacgag tagctggtat tggtggaaca gtaaaaatca ttagttttaa
     5401 aggtcaaggt acaagtgtag aaatcaaggt ccctttgatg aaggaggcat agataaggat
     5461 gataaaagtt ttattagtag atgaccatga aatggtgcgc ttaggcgtct ctttttattt
     5521 atctattcaa gaagacattg aagtaattgg agaagctgaa aatggacgac aaggctatga
     5581 gaaggcgatg acacttcgac cggacgtcat tttaatggac ttagtcatgg aagaaatgga
     5641 tggtatcgaa tcaacaaaag caatcttaaa agattggcca gaagctaaaa tcattatcgt
     5701 aaccagtttt attgatgacg aaaaagttta tcctgccatt gaagcaggtg cagcagggta
     5761 tttgttgaag acctctaccg cacatgaaat tgctgatgct ataagggcaa cgcaacgtgg
     5821 cgagcgagta ttagaaccag aagtgacaac aaaaatgatg gaaaaaatga gtcggcgaaa
     5881 tgagcctgta ttacatgaag aactaacgaa tcgggaaaat gaaattttaa tgctgatttc
     5941 tgaaggaaaa agtaatcagg aaatagcgga cgaattgttt attacactga aaacagtaaa
     6001 aacacatgtt tccaatatat tggctaagct agaagtggaa gaccgtacac aagccgctat
     6061 ctatgcattc aaacatggtt tggtgaaata aaaacgatga taaagaggat aatcaaaagc
     6121 tgagaaaata actattattt ttcttggctt ttttacaata atgatgcttg cttttgtttt
     6181 tgtaaaggct ttgttatact gagaaaagaa gatactaaag gaggaaaacg gtgaaacaaa
     6241 attttgcaat tgtaggtctt ggacgatttg gcggaagtat ctgccgaaca ctgatcgaag
     6301 ctggtcaaga agtactggct attgatagta atgaagatcg ggtcaatgaa tatatgaata
     6361 tagccactca tgctgttgtg gcaaatgcac aggatgaaat gacacttcga tcattaggca
     6421 taagaaattt cgatcatgta attgtcgcta ttggagaaga tattcaagcc agtatcttag
     6481 ttactctgat ggtaaaggaa atgggcgtac caaatatttt agcaaaagcc caaaatgagt
     6541 atcatgccag agtacttgaa aagatcggag ctgatcgcgt cgtccatccc gagcgagaca
     6601 tgggaataag gattgcgcat aatttagtgt caaagaatat tttagattac ctagagttgt
     6661 cagataaata ttctttagca gaaatccgag tctccaatcc taaatttttc aacaaaacat
     6721 tagctgaatt aaatttcagg caacgttttg acttaacagt agtcgccata cgaagagtag
     6781 atcaaacggt tatcgcttct cctgcagcag atgaatatgt tcgtgaaaat gataatctac
     6841 tggttattgg agagacaggc gatgtggata ttctagacga taagatgaat caatagaaag
     6901 aaaagagaaa gtaggttgtt gggatgaaat taacggtaac gccaaaagca caaaagtggt
     6961 ttgactcaga aattgatctg ccagaaactt acggaatacg tttttttgga aaagtctacg
     7021 gcaaaacaga ggttcatgat ggtttttcga ttggaatgtc agttgaacag ccagaacatc
     7081 ctgtaaagaa agtggaaatt gatgggacac ttttttttat cgaggaagca gatgaatggt
     7141 tctttaaagg atatgattta cttgttgatt atgatcccaa cctggaggag ccaacctatc
     7201 actttaaaaa acaataaaaa aagagagggt gacacaattt ttgtcacctt ctcttttttc
     7261 ttttgaaaat attgttttca gctattaata tcctgcagac aattttactt gattggtttg
     7321 aagctcatgg gtggcaaagt agcttttcag attggttaaa aaaatagcca ttaatttctt
     7381 ttgaaaatca ggtgtcaaac ctgcaatgtg ggaagtaatc agtacattgt ccattttcca
     7441 aagaggatga tcttgtggaa gaggctcttc ctcaaaaacg tctaatgctg caaaggaaag
     7501 ttgctggtta tttaaagcct gcaccagatc ttgtgtctta acagaagcac cacggccaac
     7561 attgatgaat acagattttg gatcaaagtg ttcaaacata tgctgatcaa agagcccagt
     7621 tgtttcctcc gttagaggta agatattgac tacgaaatct acttcaggaa gaacttcctt
     7681 tagttgattt aaagaaaaag tcttttccat tccttctgct ggatgaccgg atgtattgat
     7741 tccatagcag ttcatgtcta atgctttgca tttttttgca atcatttttc caatatggcc
     7801 agttccaatg attagtattt ttttcccttg gatagattgg taatggaccg atgaacctaa
     7861 ccatttcatg tcactctgtg ccttttgtgc ttgaaaaaga ccacgagaat acccaaggat
     7921 gattcctaag acatgctccg taatcgattc actgtggatg ccactaccat ttgaaagtaa
     7981 aatatgtttc tttgaaaaag tctcaagggg tagctgatca acaccagctg agatagattg
     8041 gacccatttc aaggtagaag aggctaatag tttttcttgg tagtctgagt tccagcccaa
     8101 actgatctct acattttgta gatcctctgg ttgtaattct gttttaaaga tataaccagg
     8161 cgctatagta tggatttctt cgataaattc atcacgaaat ggacgatctg cataaatgat
     8221 tctttctgac atagttaatt tcccgccttt ctttactcta agtgtagcgc atacaagaag
     8281 aactttgaag cgccttgctt gttttttgag aaagaaatat ttttcaaata aaaaaggggc
     8341 tgtgacaaaa aaatgtcaca acctctaaaa gggtctattg aagtagaaat aacgagttgt
     8401 ctttatttct taattgatcg atatttttgc ccatcctttg acagcttgag caaaaataaa
     8461 gattcctgca aaagcaatga aggcgctagt gtcaaaagaa ggaagaaaga ccatcaagat
     8521 tgttgcaatt atagtaggca atgaaattga atagatcaat gtttttaaac aatcaagaaa
     8581 agtagctttt gttagtcgaa agcgtgcata gagaaaagca gcaatgttgg taaatagcaa
     8641 agtgatcagc agattcagaa aactaggata aatagaaaat ataaatgtca ggacttttat
     8701 ccaaagtggt atagatgctt cacttaaaaa agaacggagc tgcttacctg ttaagttttt
     8761 taaagattca ttggtgtagg gaagttctaa ttggttattg ttcaacaaag cagaagtcgt
     8821 gcctgtatta ggaagagcta tgataagttt gttttttaac atcccgacac taacaaaatt
     8881 ccccatcaaa tcagtagaga tgtcctgttc tgttcgtttt ccctctggat caaatgtgaa
     8941 gataatggag tttgtttggt aaatgaatcc ttctttttct tcggtttgaa gctgcccgtt
     9001 ttggattgta aaatcaggaa tgcgagtagc aatcttttgc ccatccaatt gaatgttgtt
     9061 taagacttga aaaacttgaa aagagattgg caaagccata attatactca aaactaaaag
     9121 atagacaatg gctttccaaa atgggacatt tctcgcctcc tttaggtctt tgaatcgtat
     9181 aaaggaactg ataattaatt gttttgttgt cataagtact cctcatctag tagtgtcatc
     9241 acttgcaatt ctagcgaagt atcaagtgaa atacaagtgc tttaaggaaa cagctgaatg
     9301 attggtgaaa tatcaaaaaa atgttattct tgtctaaaga ctatccaata taaataaaat
     9361 ggaggaagga atagtgccta cacagccaca gagatcatca aaaaaactat ttggagtagt
     9421 ggttttgaat gcggtgatca ctttatcaga atttattgga gggattatgt cagggagttt
     9481 gtctcttgtt tcagatgctt tccataacct tagtgataca ttggcaatta ttttttctta
     9541 cggggcacaa aaaatggccc gaaaagaagc aaataaaaaa cgtacgtatg gctaccagcg
     9601 tttagaaata ttgagtgctt tcatcaactc attcatattg atcatattat ccttgttttt
     9661 aaccgttgaa gcattcaagc ggttcacttc accagaaaag ataaatagtc atttgatgct
     9721 aacagtagca gttattggat tgctcgcgaa tttgttctca gtattattat tacgacaaga
     9781 agcagatgaa agtttgaata taaaatctag ttatttgcat ttgttaagtg atacactgtc
     9841 ttcggtaagt gtgattatcg gagcaatttt gatccgtttt ttcgatatct actggatcga
     9901 tccagttatt acactgatca tttcgatata tatattgata gaagcgataa tggtgatcaa
     9961 aaaagctgcc gctattttga tacaaagtgc acctgctatc gactatgaaa aaatggaaca
    10021 agaaattgaa gcaatcgatg gggtaaagga tgttcatcat gtccatattt ggcagtatag
    10081 cgaaaagata attattttcg acggacatat tgattttgaa gatcagctac taagcgagat
    10141 tgaaaagata tatcctcgta taatttcttt attaaaatta aaatatggta ttacacatgt
    10201 gacgatccaa gcagagacaa aggcaaagga tcaaaaaaaa ttaatttttt taaataaaga
    10261 tgaaagttat tgaaatatag agtatgataa ataagaattt ttaataaggt aggttggctc
    10321 atgaagcagt atcgacagtt aaaaggatat ttagaagcaa aaggatattg ggagatacta
    10381 gtctatctct tttttggtgg tttggctacg attgtaaatt ttgttagttt tgctctcgca
    10441 cgccaatatt ttgatttaag tatggcctta tccaattcta tttcgtggtt ttgttctgta
    10501 ttgtttgctt ttgtaacgaa caaactttgg gtattccatt caaaatcacc gaattttaca
    10561 catgcactta ttgaatgcgg taagttcttc ttctaccgta tcctttctta cggattggac
    10621 atgggggcaa tggtattgtt gatcaatgtt atgaacagca atgagtatgt ggcgaaaatc
    10681 atcactcaaa ttattgttat ccttgcgaac tatattttca gcaagttgtt tatttttaaa
    10741 gaaactgagg tttttgaaga agaagtaggt caaagtgaaa aagacgacta ggcataacaa
    10801 ttgaagaatt tccttctctt tgttactctt tgtaatgtag acattattaa gaaaacattg
    10861 aggaggaatt tttttatgac ttacacatta ccagatctac cttatgcata tgacgcattg
    10921 gaaccttata ttgacgaaga aacgatgcat ctgcatcatg ataagcatca caatacttat
    10981 gtgacgaatt taaattcagc aattgagaaa tacccagaat taggcgaaaa aacaatagaa
    11041 gaattattat ctgatatgga cgctattcca acagatatca agacagctgt acgtaacaat
    11101 ggtggcggac atgctaacca ttcatttttc tgggaaatca tggcaccaaa tgctggtggc
    11161 gaacctacag gagaaataaa agaagcgatt aatgaagctt ttggtgattt ttcttctttt
    11221 aaagaagaat tcaaaaaagc agccgctgga cgatttggtt ctggatgggc ttggcttgta
    11281 atggaaaatg gaaaattagc tattacctct actgcaaatc aagattctcc attgatggaa
    11341 ggaaagacac caattctagg tttggacgtt tgggaacatg cttattattt gaaatataaa
    11401 aatgtccgac cagattatat tgcagcattc tggaatgtta ttaattggga tgaagtaaac
    11461 aaacgtttcg aagcagcaaa ataaccattt cctccgtcat atcagtctta aaaataattt
    11521 ggaaaataaa agagcgaaag cttgctagcg ttttctaaat tgggtataat gttcttgcaa
    11581 ggttacttgc aagaactttt ttggaggata tacatttatg gaacacggaa cggttaaatg
    11641 gttcaacaat gaaaaaggat ttgggtttat tacagtagac ggcggagatg acgtatttgt
    11701 tcatttctca gcaattcaag gagacggctt caagagccta gaagaaggtc aagaagtaga
    11761 attcacgatt gttgaaggtg cacgcggacc tcaagctgct gaagtgacta aattataata
    11821 atttgttgaa taaagacacg acttcttaga gagtcgtgtc tttttgtcta tttatgaagt
    11881 ttttagattt tttggctaag taaatgcatt tgttcacttg acatgtccta actaattatc
    11941 aagcaaggaa cattttcttc gttagtaatg gattttaaag aaatttcagt ttttggatgt
    12001 tgaataaaag accatttgtg aaaccactag tatacatact cattaccatg tcaattctat
    12061 tactttaaaa gaaaatcgtt ttactttgaa gaggagcata tctatccatt aaaagatgat
    12121 ggtaatgcaa tcactagttc gagtcatttt aagagccatg cagtgagctg gaaataaaac
    12181 gaatagaaga tgggtttaac aaaaggacca gtcataggaa gaaattgtcg tgaaatcgaa
    12241 tgataatctg aacggtaggc aaagactgtt aaaaagatgg gaaaggtatg tgcgatcatt
    12301 ttactgcacg attatttgga aaataccttg ttgttcgctt tttctggaaa aaatacataa
    12361 aaaaagataa aacgattgcg aactgcgtgt attcggtctt tcgatctttt tcacggtatg
    12421 gtatgatagt taagaatttt gagaaatttt aaaaaataat aatcgttaca caaaaatgtt
    12481 ttttaaagtt ttcttatgat taaaaagtga atttgctgat tgaacagtta tatgagacaa
    12541 tattttagaa aatgtgaaac agaggtgtat tatgaagcga tggcaaaaag ttctattaac
    12601 cttgttaggg gtattcgttt tgctgattgc cggattatca gcatacggaa tcagatttat
    12661 gggagaagcg agccaaacag taaacaaaat ttctaaaaac tctaatcgaa tatcctccaa
    12721 acgttctgag agagtaagca ttgatgacaa agaacctttt tcggttttgc tattaggttt
    12781 agataccggt ggattaggaa gaacggaaca aggacgttct gatacgatga tggtagtaac
    12841 agttaatccg aaacaaaaaa aatcaacgat catcagtttg gaccgagata tttatacgaa
    12901 tatcgtaggt tatggaacgg tagataaatt aaatcatgcc tacgcatttg gtggtgtcga
    12961 aatggccatg gattcaattg agcaactgct cgatattcct attgatcatt atgtaacgat
    13021 caatttggat ggcatggaag atttgatcaa tgcggtcggt ggcatcaaag tgaataataa
    13081 aattgacttt actttggatg gtgtccatgt accagtaggt gaacaaacat tgaatggaga
    13141 aaaaggttta gcctattctc gaatgcgaca cgaagatcca gaaggcgata tcggtcgaca
    13201 acgtcgtcag cgggaagtag tgacgaaaat cgtcaataaa gttttaagtt tagatggcgt
    13261 aagcaattat agaaaaattt taaaagcagt tgagaacaat gtgacgacgg acttagattg
    13321 ggatgacatg cttgatgtag cgacgaacta caccccggcg tttgaaacaa tcaaacaaga
    13381 ccagttgcaa ggcgaaggac aaatgatcaa tgatatctac tatcaaattt taggaaaaaa
    13441 tgatcttctt tcgatccaaa atgaactgaa gaaacaatta aatataaaaa caagcgatac
    13501 attacctaat ttgaaaaatg agaatgcttc aatgatgttc tttgatgatt cggaagatgg
    13561 cgattcgaca aacggtgatg gatcgaatag tgaagggtac accgattatt cttcctattc
    13621 agaaaacaca tatgatcagt accaagatcc gaatacctat tatcagcaaa cagaagatac
    13681 aagtcagtac tatacaccaa gtcaagatac tcaaagttat gatccttacg ctggacagga
    13741 acaaaatggt tatggttatg accagaataa tgagtatgga acaacaagtg ggtactagaa
    13801 aaaaatagtt tggttaataa agagtgccac ctaaattaga caaaaaa
//
LOCUS       DAZUJR010000076        13584 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.076, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000076 DAZUJR010000000
VERSION     DAZUJR010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13584
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.076"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1410
                     /locus_tag="ACG804_002211"
     CDS             <1..1410
                     /locus_tag="ACG804_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4833132.1"
                     /translation="EKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLNDINNIK
                     KEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDEPDYLQL
                     TECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRLGGFNSW
                     ELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTIDSKFIEE
                     IKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDFQQLHQV
                     FIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKFYLLNEE
                     QTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYIVTNSDV
                     HYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDAVQYENI
                     IPISINTIDRAIISAVQNK"
     gene            complement(1502..1867)
                     /locus_tag="ACG804_002212"
     CDS             complement(1502..1867)
                     /locus_tag="ACG804_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HFS4833133.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(1864..2229)
                     /locus_tag="ACG804_002213"
     CDS             complement(1864..2229)
                     /locus_tag="ACG804_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HFS4833134.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(2421..2669)
                     /locus_tag="ACG804_002214"
     CDS             complement(2421..2669)
                     /locus_tag="ACG804_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833135.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            2668..2796
                     /locus_tag="ACG804_002215"
     CDS             2668..2796
                     /locus_tag="ACG804_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HFS4833136.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            2853..4547
                     /locus_tag="ACG804_002216"
     CDS             2853..4547
                     /locus_tag="ACG804_002216"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050151 - oleate hydratase activity
                     [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HFS4833137.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            4647..4943
                     /locus_tag="ACG804_002217"
     CDS             4647..4943
                     /locus_tag="ACG804_002217"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833138.1"
                     /translation="MQAFEHRLPRGCEKAALHQVIRTPKLKLLLMFLTWLDLLPQMQA
                     FEHHLPRGYEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQAFEHRLPRGYEKGV"
     gene            5321..6454
                     /locus_tag="ACG804_002218"
     CDS             5321..6454
                     /locus_tag="ACG804_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HFS4833139.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            6485..6805
                     /locus_tag="ACG804_002219"
     CDS             6485..6805
                     /locus_tag="ACG804_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HFS4833140.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(6834..7298)
                     /locus_tag="ACG804_002220"
     CDS             complement(6834..7298)
                     /locus_tag="ACG804_002220"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4833141.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(7429..8682)
                     /locus_tag="ACG804_002221"
     CDS             complement(7429..8682)
                     /locus_tag="ACG804_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFS4833142.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(8711..9028)
                     /locus_tag="ACG804_002222"
     CDS             complement(8711..9028)
                     /locus_tag="ACG804_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFS4833143.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(9054..9374)
                     /locus_tag="ACG804_002223"
     CDS             complement(9054..9374)
                     /locus_tag="ACG804_002223"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFS4833144.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(9838..11253)
                     /locus_tag="ACG804_002224"
     CDS             complement(9838..11253)
                     /locus_tag="ACG804_002224"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFS4833145.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(11270..12586)
                     /locus_tag="ACG804_002225"
     CDS             complement(11270..12586)
                     /locus_tag="ACG804_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFS4833146.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(12736..13434)
                     /locus_tag="ACG804_002226"
     CDS             complement(12736..13434)
                     /locus_tag="ACG804_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="HFS4833147.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
BASE COUNT         4305 a         2767 c         2340 g         4172 t
ORIGIN      
        1 gagaaaaata ttttaagaca gctgttttta tgtgggcaat tctatgtaaa taaagaagtc
       61 aatctagaaa agctctccaa tctcctgcat gtttgcaaaa ccactttact caatgatatc
      121 aataacataa aaaaagaatt tgaagaacag atcgcttata cacatcggga aaaggaccgt
      181 tacactttat atttttcaga acatatacct cgatgcaaga tcatgcagca attgtctcaa
      241 aattcgttgt ttttaaaaac ttgtctgctt tatttggaag aagatgaacc tgattatctt
      301 caattaactg aatgtgaatt catctctgtc agcaaagctt attcattaaa aaaacaagta
      361 ttagcttatt ttaatgactg cgggatcgaa atcgaccgct actcccctcg attcactgaa
      421 atggaaagac gtctgctgct tcttaatgtg tcgtatcgtt taggcggttt taattcttgg
      481 gagctacctg aatcgttttt tgaacgtgcc gatcgtttca ttgaatccgt aacggaaaat
      541 agtggcagat tttatgataa agaaaataaa gaaatcttat cgattggttt tgctatcagt
      601 ttcctacgcc agcaagtgtg tgctgtgaca atagattcaa aatttatcga agaaatcaaa
      661 aaacgtccta tttacaatta tgtcgaatca gcatgggaaa acactgattt ccaaacctat
      721 tataaaaaag aagaattcgc ctttattttg acactattca atctttgtaa ttatggtttc
      781 cattcttatc agttgattgc ggaagacttt caacagctac accaagtgtt tattgacaat
      841 actcccgaaa taaaagaact agttgctacc tttgaatctc acttcaatca agaattattc
      901 ggaaaccaac cgttcgaacg tgcgctgatt catctgatgc gttcggcttg ggataactat
      961 caattattca tgccagaaaa attttatctt ttaaatgagg aacagacaaa tttatataaa
     1021 gaagtccaga caattttttc cagctggtcc agccagttac cttatgatct acggttgaat
     1081 cctaattgca tgcgggcttt tgtgatcgaa ttgagcggaa ttctccgtct gacaaaagaa
     1141 catctgacta tctatatcgt cacaaattcg gatgttcatt atctgattta tcgggaagcc
     1201 ttggaagctg taactacttt cgattttcaa gttgcaccaa caatttattc aagtatatct
     1261 gatataaaga agtatgcgca gcagtcctca aaccgggtat tatgtgaacg tacattatat
     1321 acaccagatg cggtccaata tgaaaatatt attcctattt cgatcaatac gatcgatcga
     1381 gctatcattt cagctgtgca aaacaaataa ggggctgtga caaaaatcat gtcacagcct
     1441 cttatttgtt gaagatgccc atttctgtaa caatctcttg atacacgtca ggctcacaac
     1501 ctcacttatt ttggacatct acgggtccga tctctttatt taaaaaataa gaaatgatgg
     1561 ttcggataac taccaacgcc gctagttgga aaatatcctg caaggtaggt ttgataatcg
     1621 attcgatgat cccagctgaa acaagaattt ccaaacttag aagtatatag cctcccaaca
     1681 tctttttaat agcattgttc tcgctgactc ggtcgctttg cacttttgta tggacaaata
     1741 aatatttcaa aaaatccttg attgatagac aaacacccca aaccaataaa cagatagcaa
     1801 agatatcaag tcccagtaca agtttttcga aatatggaag aagaaactgc atcaactctg
     1861 tcgtcatcct acctctcctc ttctttgttt ttctttgtct tctatttcct gattcaagaa
     1921 ataagaaatg actgttcgaa tgataataat aagtgcaagc ttcaaaatat ctgtccaagt
     1981 cggcttgata actgactcga tgatatcagc aacgactagt acttccaagc ttaacaaaat
     2041 ataacttgct agcagttttc ttgtatctgc attacgagta ttacgttctg catagttttt
     2101 cttgacatga gaccaatcaa aaagtttgaa tagaacaaga acgatcccga caattaagat
     2161 accgatagaa caaatattta aaatagcaat gatccattct agaaattcaa ttaaatttga
     2221 gcgaaacata tacgctacct actttctttt aatttgttcc tattctttta ttgtaaaaga
     2281 aagttacctt gttcgtctat ttaaaagttg ttctaatgat aacggttcgc ttaaattttt
     2341 ctttttcact ctcccatttt tctccctcca tccataaatc gtggaagtat ccaaaacaac
     2401 gtagcaagtt aaaataaggc ttagtccgtc atcagctttt caaagaagca ctgtctcggt
     2461 gctttttttg tacccaaatt tctaaaaata gaaccataca cctcctcaaa tcttttcttc
     2521 ttacctaccc tatttttatt tacaggaaaa tcagacactt cttctttttt gtcaaaattt
     2581 cctttttctt ctcgtcctat catttggcat tctaataaaa acgaactatc cttggatata
     2641 gaaagagaaa acaaggaggc gtttttcatg agtaaaaaat taatcaaagt cggcatcggt
     2701 ttaggtttgc ttgcccttgg cgctgcatat ctaggaaaaa agacaggact attcgaagat
     2761 gacagtcatt tatatgatga attcgaatca atctagcatc ctatttagtt gaatcactac
     2821 ggacatactt ggaagacatt ggaggaatca caatgagaaa aagtaaagca ataatgattg
     2881 gtgccggtat tgccaatatg gcagcggctg tttatttgat tcaagaaggc aaatggaaag
     2941 gggatcagat caccttttat tcattggatg atcacggttc aaatgatggt gcaccgaccg
     3001 acactgtagt ggatgaatat tggaataaaa accatccatt agaaaaccaa aaaggctata
     3061 ttgctcgagg cggtcgcatg cttaattacc gtacctatgt agatttgatg gatctgttaa
     3121 gtcgaatacc ttctgttact gagccaggga tgactgctga agaagatacg agagattttg
     3181 atgcaaaaca ccgaaccttt gacaaagcac gtttgatgga aggtggcaaa ggaatcattg
     3241 atggcggaaa actgggattc aataataaag accgtattct tctgactaaa ctgattgcta
     3301 tgcctgattc agaagaagaa aaactagaca atatcactat cgaagaatat ttcaaagatg
     3361 atccacactt ttttgaaaca aacttctggt ttatgtggga aacaacattt gctttcagaa
     3421 cacgtagttc tgctcaagaa ttgcgtcgct atatgcatca aatgatttat gaattcactc
     3481 aaatcgaaca tctagtgggc gtcaatcgaa cacgttacaa tcaatacgaa agtattatgc
     3541 ttcctttgat cgagtacttg aaagaacaag gatgcaaaat cattttgaac cgccgtgtca
     3601 ctgactggga attcaaagaa acaccgatgc aagatgaaat cactgtgact ggtttgaaaa
     3661 ttaccaatac actgactcaa gaagaagaat acgttgtggt cgatgaagat acagcagtta
     3721 ttttcactaa tgggtccatt acagattcag ctactttagg agattacgaa acaccagctg
     3781 tagaaaatat ggattatggt gcagcttcta gtctctggaa aaaagccagt gaacgtttct
     3841 acaacttggg aaatcctgac aaattctttg ctgatcgaga tgcaagcgaa tgggtcagct
     3901 ttaccctgac gacgaaaaac catttgttgt tgaatgaaat cacccgtatc acgactcaag
     3961 aaccaggaaa tgccttgaat tcatttattt caaccacacc gatcacgccg ttaggccaaa
     4021 aagatgtcaa tatgtctatc gtcgtgcatc atcaaccgca ttttacgtct cagaaaccaa
     4081 atgaaacagt tatttggggt tatttccttt atccaagacg acgtggcgaa tttgtggata
     4141 aacagtatat taaaatgaat ggaaaagaaa tgctagaaga actgattgga caactttcaa
     4201 aagtagatcc tggaccagtg aatattcgtg aaaaagaaac agaaattttc gacagcgtaa
     4261 taaataatat ccctgtctat atgccttatg cttccgcgtt gttcaataat cgtgccaaaa
     4321 gcgatcgacc aaaagtcatt cctaaacatt cgaccaatct ggcctttaca ggagaatttg
     4381 tcgagcagcc ttatcagatg atctttactg aacaaagtgc tgtacgttct ggagaaatcg
     4441 ctgctttcca ttttgcgggt attcctatgt cccgtcttgt caaaacaccg cgttacgaca
     4501 aagatattcc tactctagct cgtgccgcaa aaaaaatgtt tgaataatca agaggttgtg
     4561 aaaaagctgc cctgcatcaa gtaataagaa caaccaggct aaaacagctt cttatgtttt
     4621 tgatttggtt ggacttatta ccgcagatgc aagcttttga acaccgttta ccaagaggtt
     4681 gtgaaaaagc tgccctgcat caagtaataa gaacacccaa gctaaaactg cttcttatgt
     4741 ttttgacttg gttggactta ttaccgcaga tgcaagcttt tgaacaccat ttaccaagag
     4801 gttatgaaaa agctgccctg catcaagtaa taagagcagc caagctaaaa cagcttctta
     4861 tgtttttgac ttggttagac ttattaccgc agatgcaagc ttttgaacac cgtttaccaa
     4921 gaggttatga aaaaggcgtt tagtttcgag tatgaagaaa aattttgtga aaatggttcc
     4981 tcacgttttt gcataaattt gacttaatac cgagaaactg atcccttctg tcataacctc
     5041 tttttattta tgtctgtttc tttttgaaaa caactatttt ttcaacgttt actctcttgc
     5101 caatccaaca tcatctaacg gatacaacta tttcaatgat taccattaca ctaaaaaatc
     5161 ggaaacacac ctctccgaac acaaatacat aagactatag aatgtttcat ttaagaaaaa
     5221 aagcgtttca ttatcaaaaa ggtaagatct cctttaaaat gaaattatct gtagtactaa
     5281 taatgcagac aattttatga atctgaaagg agcatctcca atgaaagcag tcacttggca
     5341 aggaaaacag aaaatggaaa tcagaaacgt agatgatcca aaaatattag aaccaacaga
     5401 tgcaatcatc cgtatcacag caacagccat ttgcggctcc gatctgcatc tttaccatca
     5461 tggtgaagca gttttggaaa aagggtatgt tgtaggacac gaaccaatgg gaatcgttga
     5521 agaagtggga tctcaagttc aaacattgaa aaaagggcaa cgtgtggtta tcccttttaa
     5581 tattagttgt ggtcattgtc atttctgcct gaatcacatg gaaagccaat gtgatgaatc
     5641 aaatccagat cagttatatg gcgggctttt cggatttggc aagttgaacg gtaatcattg
     5701 gggtggtcaa gcggaatatc taagagttcc ttatgcagac tctacttcat ttgttgtacc
     5761 agataatgat cttcctgatg aaaaagtttt atttctatca gatattttgc ccacagctta
     5821 ttggagcgtt gaaaacgcag gagtaaaaaa aggcgataca gttgtgattc taggttctgg
     5881 tccagtcggt ctattcgctc aaaaattcgc tgttatggct ggagcagagc gcgtaatcgc
     5941 agtagatcca gtacagcacc gtctagataa agcggctaat tacaatgggg ttgaaactta
     6001 tttcttagaa gacacggcac aagctggaac agaattgtat gaactggcta aaggtggcgc
     6061 agatgtcatt atcgattgtg taggaatgga cggattagag cctgtcaaag aaaaagcgaa
     6121 aaatttagta agcttacaaa gcggcacaat ctctccatta cagatggcat cgcaagctgt
     6181 caaaaaattt ggaacagtcc aagtaactgg tgtttatatg actccagctt cttcttaccc
     6241 gctgcaagaa ttttttatgc gggatatcgc tgtcaagcat ggacaggcac caattatcca
     6301 tctaatgcca aaaatttacg caatgattgc agaaggacta ttcgatccta cacaaatcat
     6361 tactcattcg ctgccactat cagaagcagc acaagcatat gagatctttg acaaaaaaga
     6421 agataaaaat ataaaagttg ttttgaaacc ttgaattcag taaaaaatac aggtgatttt
     6481 ctttatgccc aaaatcaaac gaaataccca tgagatcgaa ataggaaaag aagaagatat
     6541 cgaaatacga ggacgtcgct tccgcttcta tttccaaaat cgttacacat tgatctcact
     6601 ggctgtcgat ttattaaccg ggattttcta tatttttgga agccttgctt ccttaactaa
     6661 aatccccgat cgatatggca cctattttta tttggctggt gctattttct tgacgattcg
     6721 tcctattctc agaatcgtaa ggaacatttt tatttacgac gaaaaaaaag caatgaagag
     6781 aacaagcaaa aaaaaagagg catgagaatt tttcaaatct catgcctctt ttttcaccct
     6841 atcgtatcac tttgatacag acgagcggtc gtcccacttt cttccttgac cattgtcaaa
     6901 aatgtccact cgtatcgttc ataaaacgtg gtatgatctg taattaagta aagtttttcg
     6961 tacccaagtt gatgcatttc ttttctgatt tccgctaata tccgcttggc tatcccctgc
     7021 ttacgctttt ccggttcaac aaacagggca caaagatttg gtgtcagatc agggcggtta
     7081 tggaagtcgt tttcaatgac gcccgctcct ccgacgatgg tttctttttc atctaagacc
     7141 acataccatt gaggaatact ttccttatta gcgattccag tacgaatact ttcctcatac
     7201 acaacagcag gaactcccca ttttgatgaa aaccaattcg cgctttgttt tactaattct
     7261 gggtgttctc ttaatttgat ccagttatat gtaaccaatg tttaaacctc cgactaaaat
     7321 aaaacgttta caaaaattat acaagtcttt atgaaaatta gcaatgacaa caatagtgat
     7381 gtaaaaaaaa aacggaaaac aatcacttgt tctccgtttt ttgattaatc aagcatctaa
     7441 agcttctttt cttctttctt ggatcgtagc taccttgacg aacggtagat agatcaaaat
     7501 agaaagaacc aaattgacag cggctagtac accacctgca atactttttg ttgccaatac
     7561 accgccaata attggtggag ttacccatgg aggcataacg gtagctgctg gcactaaacc
     7621 tgtagaagtc gcaaagtaag caacactaac taagaccatt ggtgtcaaaa taaatggaat
     7681 gaacatgatc gggttcaaca cgataggtaa cccaaacatc gttggttcat taatattgaa
     7741 gacacctggc gcaatcgaca agtttgttac aaccatatat ggtttgtttt tacgtcctac
     7801 taaataaata gctaacagta aacctaaagt tgcacctgtt cctcctaagt tgacaaagct
     7861 gtcaaagaaa ggtttgttca cgataaacgg tgcgctatgc ccagctgcga ttgcattaac
     7921 gtttgcttca atggctggcg cattgattgt ttgcatcaaa ggatcgacca tattcgctcc
     7981 gtgtaaacca aagaaccata agaatggtgt gataaatgca agcagtaagg cagatggata
     8041 agagtttgca agtcccataa atggttcttg gaccactgta tagaaagaac ctacgatatc
     8101 atcaacaccg aatgcagcaa aaattgcagc aactaaagca aacgcagaga tagtgatcat
     8161 tgctggtagt aatgaagcaa atgcttttgc aactgccggt ggcacaccat caggcatttt
     8221 gatgatcaat ttttcatttc cgcttaaacg tacaaagatt tctgttgaaa taatcccaac
     8281 aataatagca ataaacaaac cgtttgagct catacctaat gctccgccta aagcgaagaa
     8341 agagcctaaa gaaatcacac ctgcggaaac accgtctttt cggtagccgt tagctaaatg
     8401 ataagcaagc aagaaagcaa tcaagacaga aagaatggca aatgtaccgt tccaagcagc
     8461 agccccgaat cctttccatg attcaccacc aaaaattgag ttcatcaatt cttggaaccc
     8521 gggaatcggt aagttattga tcattactgc taatgctcct aagatcatta acggcatact
     8581 caccataaat gagtcccgaa tcgcaactaa atgccgttgt gcaccaattt ttgatgctac
     8641 aggtataaaa tgtttctcca taaatgcaac aaatttatcc ataaatcttc cctcttttct
     8701 ttactgtaga ttacgcgttc aatcgacgat acagatcaat gatctctttt gctaaatctg
     8761 taaaagctat agatgtcatc agatgatctt gactgtggac cgtcaaaagc gtgacttcaa
     8821 cgtgatttcc ttgtgcttct tgtgtcagca tctctgtttg agagtgatgt gcttggacta
     8881 aagattcctc tgcatctttg attttttcat ctgctaaagt gaaatcacct tttttcgcag
     8941 cagcaatcgc ttccattgca tcgctttttg catttccgcc aaacatgatc agacccatga
     9001 tggcttctag atttttttga tcttccattt attgtatcct ccgataattt ttattatttg
     9061 tttattagtt tttctgcttg gtcgagtact ttttcaccat tcatcatgcc atagtcagcc
     9121 atattgatta catctaaagg aatgccttta ggtgctagct tttcagcaaa ttgattttgc
     9181 ataaagcgta cttgcggtcc taaaagtaaa acgtctacat ttttagattc tagttgatta
     9241 tccgcatctg aagcagatac agcaaagatg tctgcttcca ttccttttgc ttctgctgcc
     9301 ttttgcattt ttgtgactag gagacttgta ctcattccag ctgaacatac aagcatgatt
     9361 gttttctttt ccattttaaa cacgttcctt tctatactta cacttgtata taagcaagta
     9421 gcgtgccaac tttaaaagcg ctttaaaaag ttgatatcat cacatttaag gtctatacca
     9481 agttgcatac acactaaaaa agaaagcgca cactaaacac acaaattaat ttttattacc
     9541 ttttttcttt taacgtgcac aaaaaaagtt gtgacacaaa acttgtcaca acttttttca
     9601 aataaacggt attcaaaagc ttgcatctgc ggtaataagt ccaaccaagt taaaaacata
     9661 agatgttgtt tttactttgc tattcttatt acttgatgca ggacagcttt ttcacaacct
     9721 ctcaataaac ggtgttcaat cagctgaccc tgggtattag ctcaaaacgc tggattcaca
     9781 acctctttta tttcaaataa ccagtaaata caatgaacat ctacaaaaaa cttctattta
     9841 tttatagatt tcgtcaggca aatccaattc tctcttatca atcaaagtct gataccacga
     9901 agcagatttt ttcaatgttc tgcttcgttc atcgttcaat tcgattcgaa ctaatccata
     9961 tcgattctta aatgcattca ttggtgacac acagtcagtg aatgcccata acatatagcc
    10021 ttcgcaattt gcgccttctt ctgttgcttt gatcaagtaa tgcaaatgct gtccgataaa
    10081 ttcgatacgg taatcatctt gcacgattcc tttctcatcc atatactgtt cttcatattc
    10141 tcttcccata ccgttttctg ttatcagcca agggatatta tgataatttt cttttagata
    10201 catggctata tcatacatga ttttcggata gatttcccat cccctggaat tattcatttt
    10261 cttcccaggt aaatcaaaga cttcataata tcgttcagga tggaaaggtg tctcttcatt
    10321 ccattgataa cgaggggcgc gaacgcgttt aggataatat tgattgattc caaggaaatc
    10381 tactgtatga tgctgaatcg tttctaaatc ctctgttgca ggatcgaaat aaatcgattg
    10441 tttttgacac aactccagga actcttctgt gtagtatcct tttaccatcg gatcaaaaaa
    10501 tactcgatta taaaacaaat catacatata agcagctttt tggtcttctg gagaattgga
    10561 tcgagcatag accatttcag gatttaaaat acagccaatc cttccaccat aatttccgct
    10621 gcggtaaatc tctactgctt tagccgttgc taaaacttta tgataattcc acatcatcca
    10681 cttttttgtg ttttgttcat gcggccagcg aacagcatcc aaatagcaac gcgtttgggg
    10741 aacgattggt tcgttgaatg taaaccagtt ttttacccta tcaccgtaac gatcaaaggc
    10801 aatttgagca tacttagcat aaaaatcaac tacttttctt gaagaccagc catcatattt
    10861 ttccaaaaga aaagctggga cttcataatg ttccaaacaa atcatcggtt ctacgtctgc
    10921 ttcgatcaaa gagtcgatca tttcacttat atgctgagca tattcttcat ctactataca
    10981 gttctcataa tcagtaaaaa aacgagccca attgatagaa gtccgataat gtgtcagatg
    11041 gatggatttc atcagatcca catcctgctg gtattgttcc ataaaattag ttgctacggc
    11101 tgggccatac ccattatgcc aaacaaaatg ttcattttta taccagctat ctataaacga
    11161 atcctgtcct tctttttttc ctttccaacc ttccgtttgc caagcagaag atgcagcacc
    11221 aagaataaaa ttttttggaa tagtaatttt catgatttcc tcctgttttt tagatcccat
    11281 cattttccac acgatttgct acttttacaa atggcagata gatcaaaata gaaacaataa
    11341 tacaaacaag ttgcgtaata actgcaccga tatttcctgc tgttgccaga taagcattga
    11401 cgatcggcgg cattggccaa gggaccatta caactgcttt cgccgcaaat cctaaagcgg
    11461 ttgcaaaata accaatcgtt ccagtgataa gaggcgttaa gataaacgga atagctaaaa
    11521 ttggattcag catgatcggc ataccaaaaa taactggttc attgatgttg aagatcccag
    11581 gagcaaggga taacttggtg atttgtttca tatcttcccg ttttccaact aacaatactg
    11641 caatcagtaa accgatcgtg actccagacc cgcccatact catatacata tcccaaaatg
    11701 gcatagtaat aatgttcggt acttcttttc cagcttcaaa agcttccgta tttacagcaa
    11761 ttgccgctaa aagcaacggt tcccgtatcg gcttcaccat ttgatttcca tggataccaa
    11821 tcacccaaaa gacttgcgca ataaacatca atagcaaaat acccggtaac ccttgtacga
    11881 caccttctaa tgggcgttgt acgacattgt aaatgatatc ataaaggtac attcctgtaa
    11941 gttctttgat gataaatccc gcagccgcga tacccgatac agtcagaatc gtcgggaata
    12001 aagcagaaaa actagcagaa acattcgttg gcacggtatc aggcattctc agctgtagtt
    12061 tcttctgttt cctcaaccag caataaagtt caatagaaag gatggagacc aacattccca
    12121 aaaataaccc tttcgtatct gtatattgtt tagccaatac gttttctact ataacagtct
    12181 gattttcatt cactaattca taaacagttg gattaacaga taaataagac atcactgcga
    12241 tgataccagg gaatacacca tccactttat tcagcttggc taattcgatc cctatcagaa
    12301 aaacagcata gatggtcaag aaacttagtg tgacatagct gatggcagat gcgataggct
    12361 ttaattcttc taaaaaacgc aagaaactta tctgtgctaa gccattttcc gagtcaaaga
    12421 ccattgctga aaacaatgtg ccaaaagcac ccgtaataat taccggaatc aatgcagcaa
    12481 atgcgttttt tatcaccatg atatacctta aattattgat tctcgttgcc acgttcccta
    12541 aaacattggc taatttatcc ataaaactca ttccagatcc cctcattcct gcttcttctc
    12601 cttgacgtca tctctttttg tctattagtc agcgcttaca tttcgatgaa cagaaactat
    12661 ttactcctct tttttaccaa atataaaaca aaaattcatc tgatgtattt atcataaaat
    12721 acatcagatg aactgtcaat tagtttcttt ttctcctatt attttctgta attctctccg
    12781 atttattgcc atatggacag tcattgcatc aaacgcagca agtgcattcc gcctttcgat
    12841 ggcctgaacg atctctgtat gaatatcgat cgtctcgatt ttcagatgct ggatatcata
    12901 atttttatta aacaaagcaa ttgattcatt aatgattggg ataatatgca gcaaggctac
    12961 gtttccgcta gcttctgcaa tcatcgtatg aaaatcgatg tctaattgaa catgttcttg
    13021 tgtgccttct cgaaaagaag tttcaatctt ttgcgttaat tttttcattt ggacgatttg
    13081 attcttcgtt gcatattccg ctgccaaacc tgccatctta ggctccaata aatatctcag
    13141 ttcaaataag tctcgtatca tccgatcctg atcttcaatc aaagaaaaac cgagtgggtc
    13201 attggcaatc cctcgcttat cactgacaaa tgtccccgct ccttgccgaa cttcaaggat
    13261 attcctggaa gctagagccc gcacagcttc tcgcaccgtg cttcgcccca cctctaaata
    13321 atcggacaat tcatattcat tcggcagttt atctcctact tgcaactgca tttcctttaa
    13381 atatctaagg atcttgtcag tagttacttc tactagggtt ttattttctt ccaaaccaca
    13441 tacctccttt tcatctgatg tattttttcg taattattat aacacgtttg aatcatctga
    13501 tgattttttg tatacaaaat tgattaatcc gttcatagac atacaaacga agaagatatt
    13561 taccataaaa aagactagga taaa
//
LOCUS       DAZUJR010000077        13419 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.077, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000077 DAZUJR010000000
VERSION     DAZUJR010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13419
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.077"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(79..621)
                     /locus_tag="ACG804_002227"
     CDS             complement(79..621)
                     /locus_tag="ACG804_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HFS4833148.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            756..1145
                     /locus_tag="ACG804_002228"
     CDS             756..1145
                     /locus_tag="ACG804_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833149.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            1149..1913
                     /locus_tag="ACG804_002229"
     CDS             1149..1913
                     /locus_tag="ACG804_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFS4833150.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            2042..2989
                     /locus_tag="ACG804_002230"
     CDS             2042..2989
                     /locus_tag="ACG804_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4833151.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            3119..3859
                     /locus_tag="ACG804_002231"
     CDS             3119..3859
                     /locus_tag="ACG804_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833152.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(4150..4818)
                     /locus_tag="ACG804_002232"
     CDS             complement(4150..4818)
                     /locus_tag="ACG804_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFS4833153.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            4952..5239
                     /locus_tag="ACG804_002233"
     CDS             4952..5239
                     /locus_tag="ACG804_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833154.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            5655..7193
                     /locus_tag="ACG804_002234"
     CDS             5655..7193
                     /locus_tag="ACG804_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HFS4833155.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            7190..8155
                     /locus_tag="ACG804_002235"
     CDS             7190..8155
                     /locus_tag="ACG804_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4833156.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            8142..9464
                     /locus_tag="ACG804_002236"
     CDS             8142..9464
                     /locus_tag="ACG804_002236"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFS4833157.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      9527..9631
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            9705..10448
                     /locus_tag="ACG804_002237"
     CDS             9705..10448
                     /locus_tag="ACG804_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4833158.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            10463..11455
                     /locus_tag="ACG804_002238"
     CDS             10463..11455
                     /locus_tag="ACG804_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFS4833159.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            11467..12204
                     /locus_tag="ACG804_002239"
     CDS             11467..12204
                     /locus_tag="ACG804_002239"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4833160.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            12194..12916
                     /locus_tag="ACG804_002240"
     CDS             12194..12916
                     /locus_tag="ACG804_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFS4833161.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(13000..>13419)
                     /locus_tag="ACG804_002241"
     CDS             complement(13000..>13419)
                     /locus_tag="ACG804_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HFS4833162.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         4424 a         2295 c         2786 g         3914 t
ORIGIN      
        1 tttaatcaaa ataataaata aaaactgtct aacatttaaa atttaattta gatattagac
       61 agtttttaag tttgtgagtt attttccttg tcgttttctc acttttttag tccagaaacc
      121 acctgaaata tattttggct cataagaaat gataaaagca cgctcttcga tttctttgat
      181 caggcgatac agttcacgtt cgctttttct aggagaaagt atttcgagaa ctagccgctc
      241 accttccagc cccattgcag aagtctgtgt cacaccataa ccgtgttctc tcagtatacc
      301 cggcaaactt ttatcttctg cgctatttgc tggcaaaatc gttgtgacca tgatgtatcc
      361 taatgccaat ttgtcttcaa tcaaaattcc gacactgata cctactgcgt aacctaacgc
      421 atagacaaat aaattcagtg gattatctaa acgatctaaa acaagggata agccgacgat
      481 ataaatcgtg atctcgacca tactgacaag tggagcaatc agtcgatagc ctttcattgt
      541 caacatgaaa cgtaacgtgt tcagagtgat ataagcaaaa ttaatgagga agatcatccc
      601 caacattttt ggatcaatca tttgtaaaac tcctttcatt tatataacaa caatatcaaa
      661 aaaaatcgta agtgaagaaa aattgaaact ttatacatac aaaaaaatga taaaatgatt
      721 ataatagaat tataaagata ggttaggtga ttaaaatgaa aacggtcaat cgtgtgtttt
      781 gtgccagcca cgtgctaagt ctccttctca gtatatactt aggtgtctat tcgattcaac
      841 agccaattga ggtagagaac attgtttttc agatgtcgct gacagatggt ttaattttaa
      901 gcgttttttt ctttttgata ctgtttattg gtaatatttt cggtagcgtt gccagttttt
      961 tgaatttttc tatttatcca ctcctttcgc tagcattagg agtggtggga ctttgttctc
     1021 tgtgcttatt tcccgagcca ttcagtcctg catttatatt atttggtaca ctgaacctgt
     1081 tccagacaac tgttggagca tggttgctat ggcgatcagg aaatttaatg aaaataggtg
     1141 agtaacaatt gaatccaatt atattgaaac gttctgtcca tcatattcca gtgttagaag
     1201 ttgttctgaa agaattaaga gaggaacgta ttcccgttgt catctattat cacggatggc
     1261 agacaagtaa ggagttagtt ttgacgcaag gaagaaaaat tgcgcagcag ggcattcgtg
     1321 tgatcctgcc agatgcgatg aatcatgggg agcgcaaaca gccggtttct tctattccat
     1381 cctatacatt ttgggatagt atctacggaa atctgtttga atttgacaca cttatcaagc
     1441 atttagaaaa aagaggtctt ctacatgatc agcttgcagt tggcggggtt tcgatggggg
     1501 gaatgacaac atgcgccttg ttggctaaac atcctcatat agtagcgggc gtgtgtttga
     1561 tgggttcccc tgcacctttg gaatatggaa aagaaatcgt aaggcgcgca tcggaatata
     1621 attatgtcgt accaaaagac tattttgatt tgatttcatg ggttaagagc tatgatttgt
     1681 cattgcagcc ggaaaagtta gctggacgtc ctctgttctt ttggcatgga caagctgacg
     1741 aaaaaatccc ttatatacaa acggaacgat ttgtagaaaa aaatcggcat aagtcttacg
     1801 gaaaagaaat tgtttttcgt tcctcaaaaa cacagcgaca tatggtacaa ataccactaa
     1861 tggaagaagc ttccactttt ttagcaaaaa atttgataaa aaagtataaa taattgaaac
     1921 ggaaaatcac tcatgacgat agaggatttt ccgtttttta ttttgggcta taataaactc
     1981 tgttaggaaa atttggtata attgatagta agaatgacaa catgttagaa aggaagagag
     2041 catgcccact ttagcagatg ttgcaaaacg tgccaatgtt tcaaaaatga cggtctctcg
     2101 agtcatcaat catccggaac aggtgactga cgaattgaaa gagttagttt tctcagcaat
     2161 ggctgaactg gattaccgtc caaatattgc tgcaaaagca cttgtcacga atcggtcgca
     2221 gatcatcaaa ttatttatac tggaagaaat cgacacaact gagccctatt acatgaattt
     2281 gctgatggga atcgctaaac ggatcggtaa agcgcattat tctctccaat tagttacaaa
     2341 tgatgccttc gacgtcggtt cttgtgatgg atacatcatc acaggtgtca gaaaaaaaga
     2401 cttcgattgg atcgaccgtt tggaaaaacc agttgtcttg tttggggaaa attctgaagg
     2461 atatgattat gtagacagcg ataatgaata tggtacagca aaagcaacgc aatatgcctt
     2521 agaaagagat tatcaaacga ttatttatat cggtatcgaa gtggacgagc cttttgaaat
     2581 ttcaagggaa actggttatt tatctgtgat gaaggaagtt gatcttccta gtaaaatctt
     2641 gcggtttcca aatcattcga cagaagtaga aagatatatg acagaaaact gggcagattt
     2701 tacagataaa acttgttttg tatgtagttc agatcggcta gcactaggag cagtaagagg
     2761 gattataaat gctggaggac acttgcccga agaatttggt gtgattggat ttgatggggt
     2821 atttttagac caaatcagtt cacctaaatt gacaacgatc aagcaagata ttatacgtat
     2881 gggtgaagta tgtggagaaa tgttgttaaa aaaaatagaa gaaaaagggg cgagtcaagg
     2941 ttatcgtcgt ttttttcctg aactagttat cagagagaca acgaattaag tcttattact
     3001 atatatatat ttatgaaatt catcgctatt ttcttaaaat aatcagcgca ttgctactga
     3061 aaacaatgaa tctgtgctat tattgagaaa agttccattt ttgagaagga tggtttgaat
     3121 gaaagaaatc agacgaaaac atttccgttt tcctgcgtac gatgatgagt taggcgtaaa
     3181 attaaccaac gacaagaagc gagtattatt tgacggacaa gaagatcttt tgactgaaca
     3241 gaatcagtcc ccgtttgaac agatgaaaga atttcatttc acgaacacga acaccgagaa
     3301 aatccgtcgc aagcgtcgtg caacaaatgg attgaagtca gctccgcgta aggaaaattt
     3361 ggaaaagcat aaaggaaaat taccggatta taccggccat taccaatcag aaatcacatc
     3421 gacaggacga aaaaaacttt ttggtgattc ctctcgttct gtcagacaaa gtgaaacaag
     3481 gacagagtcc aagcatacta cacgaaacgc atctgttgac acgaaggtgc gggagcgttc
     3541 ttattttgtt cctaaatatg tacccgcatc gattatccca gaccctagag aaagcaaaat
     3601 ttctgaggat catttaatcg aatcgatgaa aaaaacggat gactcttatc tgttgttcga
     3661 tacagaaccg acgccgtatc aagaaaaaag aaatggtgag ccgtctgtac gaacattcaa
     3721 tcgaacaaaa acgttagagg aaacaaagca gtcagaagaa aaaaaatcga aaaaaagcca
     3781 tggtatctta gaacgctcat tacaaggatt gatcgatgat caaggaaact ctttgggaga
     3841 aaatagctat tttaaataag tgatatacaa atttatattc ggctacagtt ggaaaggaaa
     3901 cgctgcggcg tttccttatt ttatactcta tccgaaagtt tatatcgtat cctcaaattt
     3961 ttttgagttt aagcgaattt tttctcccaa taagtaagaa aataatggca aaataaaaaa
     4021 acaaactatt ttcgcagatc gtttgcaaaa atagtttatt tttttataaa gaagatttta
     4081 ctgaataata tcattttagt ttacataatg atatttctgt aaattaaata aagtagtgaa
     4141 aaataagaat cagtgctcta actgttcaag aggatcaagt ggttcaaatg tttctgtagt
     4201 ctgttttgct tccaattggg gcaaaacaga tccaatttcc agatacttca ctttattcaa
     4261 tgtataagat agaatagaac agctaagtaa tgtatacaga aaatgtgtga gatccaaata
     4321 aagcaaggag acaactaaaa taccaaaagt aatcaagaaa agacttttgc caatcttaat
     4381 atgaaaatat ttttcaatgg cttgataaat gatatctgtt ccgcctgtgc ttccgccgaa
     4441 tcgaaagacg agaccgcaac caatgccaga aagaatacct gtcatcaaac tattgatcag
     4501 tagactatct acagcaaaat gtatatgaag gctctcccat aaatgtaaaa agaaaactag
     4561 cgcaaatgtt ccgacgatcg tccggagaaa agcgtgtttt ccaaaaagaa acaatgagat
     4621 aagcaataaa ggtaaattaa aaagcagtga agtgacagaa ggagcgaatc caaaaagatt
     4681 atgcaaaagc aaagcaatac cagtaacccc accatctgcc agcttagatg gaatattgat
     4741 tcctgtcaca gctaatccgt agattcctgc gcctaaaatg attccgcaca attctgtaaa
     4801 taaatttaat tttttcattt ctagcctctt ttcttttgaa aattttcagc aacttcttta
     4861 ttatactgac ttatactctt acttcaagag gaaaatgaaa aaaaattatt tttggctgtt
     4921 tctttttatt tatcaaataa ggagtggaaa aatgcgagca gcagacttat tgacaattct
     4981 tacaaaatca cccaaaaaaa cagagtatca aggagttttt ttggctcaag aacaaaaact
     5041 ggtgcctgtg acaatggtcc agataaataa agcaaatcaa tttatctttt tatttgaaca
     5101 cggcaaagca ccacttgcta tgaaagacat ctttcttttt ttgatgaaga accgtgagaa
     5161 agctgtttat tatcagtcaa aagaagaact cattcctctt tatggagtga aagagataga
     5221 aaataaagtg gtgatataag taaaaataag aaaacaagac gtttatgatg tcaaaacaac
     5281 cattttttac atttttggca aaaaagtgtc atgatacagt ataatattcg ttgaacaggc
     5341 caataaaggt gttctccccc acgagatttc tactttattg gctgtttctt tttattaaaa
     5401 taaaagttgt gtgtgtaaaa aagatatagc tgattccaag tgacaatttc gtatagattt
     5461 ttatggtatt cgtagtgaaa aaacgagaac caaaaagttg atccgacttt gttgcttgga
     5521 ttcttttttt gtcagcatat ttagaggtat ttttttcttt tttttgttcg tgctgtaagg
     5581 ttaaggcaag acaagttagt tgggaaaaag gaaagaaatg tttatactta aagaataaca
     5641 gaaaggaagg tcgcatgaat aattttatac aaacattaag tgaaagaaaa ggcgagttgc
     5701 tggaagctgc atttcaacat ctgtccattt ctctcatttc tttgctgatt gcagcactga
     5761 ttgctattcc tttagcgatt tgggcagcca atcataaaaa aatggcagaa gtcttattgc
     5821 agatcacggg tgtgctccaa acgattcctt cacttgcctt attaggttta cttatcccat
     5881 ttgtagggat cggaactgtt ccagcattga ttgcacttgt tatttacgct ttgcttccga
     5941 ttttccaaaa cacgtatatt ggtctagctg aaattgaccc gtctattgaa gaagcagcgg
     6001 tagcatttgg tatgtccaga atgagacgct tgctgaaagt agagcttccc atcgcattac
     6061 ctgtcattat ctcaggtatc cgaactgcct tagttttaat catcggtacg gctactttgg
     6121 cagcattgat cggagcaggt ggattaggga catttatttt gttaggtatt gaccgaaata
     6181 cacctgtttt gacattgatt ggtgcgatca gttctgcctt gcttgcaatt atattcagcg
     6241 gactgattcg ctggttgcag cataagaaac ctcgatattc catcattact ttagcagcag
     6301 tggtgtgttt atttggcggc gtttctttat atcagtctgc cttgtttaaa aatgaaacca
     6361 tcacgattgc tggaaaatta ggagcggaac ctgaaatcct gatccaaatg tataaagaat
     6421 tgattgaaga caacacaaaa acagaagttg aattaaaacc gaattttggc aagacgagtt
     6481 ttttgttcaa tgcactggat caaggtcaaa tcgatatcta tcctgagttc acaggtactg
     6541 tcctagaaag cttggtgaag gtacctgaag caatgaaaag tgctgatttg acaaaagaaa
     6601 aaacatatga cgaagcagaa gaattattga ataagcaatt cgatatgaca ttattaaaac
     6661 caatggctta ccaaaatacg tatgccttgg cagtcaagag atcttttgcg aacgaacatc
     6721 aacttaaaaa gatttccgat ttggcagcta tctctgatca gatcaaagcg ggattcacac
     6781 tggaatttat tgatcgttca gatggatata aaggaatcca agaagcatat ggcttgaatt
     6841 tttcaagtgt acaaagcatg gagccaagtt tgcgttacca agcaatcaat aatggagatg
     6901 tcaatattgt ggatgcctat tccacagata gccagctcaa ggagtacgat ctagtgactc
     6961 tagaagatga tcgagggtta ttcccagctt atcaaggcgc accgctgatg aaaaaagatt
     7021 ttgctaaaga acatcctgaa atcgttaaag cactgaataa attaagcgga aaaataacag
     7081 aggatcaaat gattgatatg aattaccaag tcaatgtcga aaagaaaaag ccgacagaag
     7141 tagcacgaat cttcctgaaa aatgaaggat tagtaaagga ggaagatcag tgactaaatt
     7201 aatcgagttc aaacatgtgc aaaaaaagta tgatggaaag tatgtcatcg atgacctaaa
     7261 tctggcaatc aaaaaaggag aaatctttgt tttggttggt ccttccggta gtggaaaaac
     7321 aactactttg aaaatgatca atggattatc taaaccatca gcaggagaca tctacttcaa
     7381 aggaaaatcg ttaaatgaat ataatctgca gaaaatgcgg tggaatatgg gatatgtgct
     7441 gcagcaaatc gctttgttcc cgaccatgac agtcaagcaa aatattgaag tcatccctga
     7501 aatgttaggt tgggaaaagc agaaaagagc agaccgtgta gatgaacttc ttcaaaaagt
     7561 tggcttatct cctgatattt atcgagatcg tatgcctaga gagttgtctg gaggagaaca
     7621 gcaacggatc gggatcatcc gagctattgc tgcaagccca gatgtgattt tgatggacga
     7681 gccatttagc gcattagatc cgatttcaag aaactcatta caagaattgg ttttgtcctt
     7741 acacgaagaa ttgggcacga ccatcgtttt cgttacgcac aatatggaag aagcaatcaa
     7801 gctaggtgat cgtattgcat ttatgaagga tggagaaatt atccaatgtg acacaccaga
     7861 gcagttattg atgaatccta aaaacgacta cgttcggcat ttctttgatg aaccgaaaca
     7921 gacgaaagag tggcgagtag aagatttagt cgtcaatgga tatttcttaa atgaaatacc
     7981 agaaaatgct cgtcaacaag tttgctttga tacgcctatg aaagaagtat attcgcttct
     8041 ttcggtgtat ccaagcattg tgatagtaga aaagcaaaga agtattgggt cgctgacaag
     8101 taaagaaatc tttgcttttt taagtcgaga ggaggaagga aatgaaaaca tatgatgcaa
     8161 tcatcatcgg ttcaggtgtg agcggcttaa gtgctgctta tggattgaaa gaagcaggta
     8221 aaacagtact agtggtcgaa gaagatctat ggggcgggac ttgtcctaac cgtggatgtg
     8281 atcctaaaaa agtcttgtta agtgcagtag aggcacgtaa tcgggtaaaa caattgagtg
     8341 gaaaaggttt taacgagatc ccaactgcca actgggaaga acttcaaaaa ttcaaacgaa
     8401 catttacgga tccagtccca gaaagccgaa aaaaacaatt agcagaagct gaaatcgatc
     8461 atctttcagg aaccgctcgt tttttggatg attcatctat tgaagtcaac gaagaagtct
     8521 tccatgcgga ttacttagtt ttggcaaccg ggcaaagacc tacgatctta ccagtggagg
     8581 gaaaggaata cttgaaaact agtgcagact ttttatcatt gcctgtactg cctaaagaaa
     8641 tcatttttat cggtggtggt tatattgctt ttgagctagc tacgattgcc aatgctgcag
     8701 ggagcaaagt aaccattgtc catcataatc aacggccatt aaaagaattt gaggcgtctt
     8761 tggtagagga agccgtccat caaatggaag catctggcat tcagtttgct tttggtgttg
     8821 aaacccaaaa gatcatttca gaaggtactc gctatcgttt agtcggaaaa gagacggaat
     8881 tagtagcaga tatgattttt tgtgcgactg ggagacagcc gaatacagaa tctttagcac
     8941 ttgagcaagc gaatatcgtc tttgataaac acggaattgc agtcaatgat tatctgcaaa
     9001 cgagcaatcc aaaaattttt gcgtgtggag atattgtttc aaggaaaacc ccaaaattga
     9061 caccagtcgc cacttttgaa ggaaattatg tagctaagcg gataacggat gcaacaagcg
     9121 aacctatcaa atatccgatt atacctacga tcgtctacgc cagtcctaaa cttgctgaag
     9181 taggagttac aaaaagtcac gcctcttcgt cagatcaagt ggtagagatg gatcttacca
     9241 gttggttcac ctatcatcgt gtcaatgaac cagttgctaa ggctgaattg acctttgacc
     9301 agcaaaatta tttgattggt gctgcagtga ttagcgagca agcagacgaa ttgatcgatg
     9361 atttgacact cgtcatcaat caaaaattga ctaaaaaaga gttggatagc tatatcatgg
     9421 ggtatccgac attggcaagt gatctctcct atttattgaa ataatcagca tgataactaa
     9481 agcgcttgtt gctttttcct tcttgtgcta cactttaaaa aatgaatacc tgtttctggg
     9541 gatgtcgtag acgacatgag agtaagttgt gaacttagac ccattgaacc tgtcagttaa
     9601 tactggtgaa gggagaaaca tagcagacgc ttgaagcggg ttactatgtc gtgcccattt
     9661 caagcgtttt ttgttattca tattagaaga aaggaggtaa caaaatgaag aaaaatcttt
     9721 atccagcagt cagtatggca ttcattttaa ttatttggca gattgttgtc atagtttgga
     9781 aaatacctgc ctttatttta cccggacctg ctgctgtatt ttctgcatta gcggcagatg
     9841 cacaagtatt actttcccat tctgtcacga cattaaatga agcagtgctt ggtttggtaa
     9901 tagctagcgt tctttctttt attactgcct tggcaatgga ttattggaag tttttagaaa
     9961 tgtcttttta tccgttacta gtgatttcac aaatgttgcc aatcatggtg ttagggccat
    10021 tacttaccct atggtttggt ttcggtatgc ttccaaaagt gatccttgtt gtcttgataa
    10081 gctattttcc gatcgtagtt tctttttcgg atacattgag gaaagtatca aaagagcaaa
    10141 tcatcttttt gaaaacgatg ggggcagata cagggaagat ttatcgaata tataaaatac
    10201 cagcgggttt atccggcttc ttttccggtt taaaagtggc tgctacttat tgtgtcagcg
    10261 gagcagtcgt tggagaatgg ctaagcgctc aagcaggctt agggtattac atgatacgcg
    10321 taaaaaacag ctaccagatc gataaagttt ttgctgcgat catttgtgtc attctattga
    10381 gtttattgct gaatggcgct tgttcattat tgaaaaaagg gtattatcgt atgctttata
    10441 ttttttaaga gaaggggatc aaatgaaaaa attatggctt ttattaccgc tactgttgct
    10501 tttatccgct tgtggcactg caaaagaaac aagtagcaaa caagaaataa aggatttgaa
    10561 aaaagtgaca cttgttttgg attatgtacc gaatactaat catactggca tctacctagc
    10621 aaaagaaaaa ggctattata aagaggctgg tttaaatgtc caaatcatcg aaccaggaga
    10681 taattcgaca agtattggtc tagtaggtgc ggacaaagca caatttggtg taagttatca
    10741 agaagatgtc acttatgctc acgcagatgg acagaatata ccagtcaaag caattgctac
    10801 agtgatcaaa cataatactt ctggattcgc caccctatca gacagtaaca tccattcacc
    10861 aaaagatttt gaaggaaaaa catatgcagg ttggcaaagt ccaagtgaag aagctgtctt
    10921 aaaagctgtg atggaaaaag acggcgggga cttttcaaaa ctgacaatgg taggaagcaa
    10981 tggagaaggg ccagaaagct taggaaaatc ctcagatatc caatggtact ttgaaggttg
    11041 ggatatgatc aaagcaaaag aagcgggtat tgaactaaac tatatcccat tgaaagaatt
    11101 agatgaacgg ttagattact atactccggt aattattacg aatgatcaac tgatcaaaag
    11161 tgatccagaa ttggtacagt cttttatgga tgccacgaaa aaaggctatc aggaagctat
    11221 taaggatcca aatgacagtg ctaaactgtt gcaaaaatat gcaaaagaaa atgatcggac
    11281 gtttttagaa gaatcacaag cattcttgtc aaaaaattat acggatgatc ctgagaattg
    11341 gggattgatg gaagaaaaag tttggcgcaa ttatacagct tttatgcagg aaaacggatt
    11401 gatcaagcaa gatgtacctt cgcaagaact attcactaat cagtttataa aataggagtg
    11461 atagatatgt caatccaaat cagccacttg aatgtagtca ttgaaaacct gaaaatatta
    11521 gaagacatcc atttcactat ccctaaagat acctttacat cgattgtcgc gccaagcgga
    11581 gccggtaagt caacattgct gaaaacttta acaggagtcc agcctatgac ttctggaacg
    11641 atcaaagtag acgatcaaaa agtaactggt ctccatacag catttagtta tatgccgcaa
    11701 gaagatatgt tacttccttg gctgagcgtc tatcaaaacg ttacgttata tcaaaaaatc
    11761 aatcatctaa caatcaatga agaacaagta agggattatc tggatatctt tgggttaaac
    11821 ggctatgaac attttttgcc ggaacaatta tctggcggga tgaagcagcg aacggccttg
    11881 ttacgaacaa tcatgaatcc ttcttcttac ttgcttcttg atgaaccatt tggagcgtta
    11941 gatgctatga ccagagggca gatgcaagac tggatgttga agctgcctaa aaaagcaaag
    12001 cggactactt tacttgtgac gcatgatatc gaagaagcaa tttatttatc agacaggatt
    12061 cttgtgcttt ccgcccgtcc ggcacatgtg attgctgaga ttcaagtgcc tgaaaaacga
    12121 cggtcacgtg aatggctact gcagcaatca gagttgaagc aaacgattta tcagttattg
    12181 gcaggtgaat tagatgttaa gtgatgctca ttgtcattta gatgggagtc agagtttagc
    12241 actccttcag caggaacaca cgattttgac gatcatcaat tgtgattcgc cagaagaatg
    12301 gaaggaaaac agacagcttg cagcaagtaa gactcaagcc ttaagttacg gtatccatcc
    12361 ttggaaagca gatagctata cgtttgaaca agttgagcct tttttgaaaa aagcaaggat
    12421 catcggtgaa atagggttag ataatatttg gacgaatgta ccgatgacta cacaaaaaaa
    12481 agtatttgag cgacagcttg cttttgcagc cataaatgag aaacctgttg tactgcacac
    12541 aaaaggatgc gaaaaagaga tcttaaatta tatccaagct taccctaatc actatttgat
    12601 ccattggtat tcttctttgg actatcaaca agactatatt gatttaggct gttatttcag
    12661 cattggtctt gatttgaaaa agaatccagc agtctggcaa ctagctaaag cagtcccaat
    12721 cgaccactta cttattgaaa cggatggact acatgcagca gagtgggctt taggggggat
    12781 tttttcagaa aaagattatg tctcactgct tgaagaacag ttaaagacaa tcgctgagat
    12841 caaagagcta tcagttgaag aagttaaaaa aaatacttat caaaacttgg aacgtttcat
    12901 tagattaggt aaataaaaaa gagatgtgac acaactagtg tcgcacctct ttttggcttt
    12961 ctttgtataa aagtaaactg tttgattaat aaatgaatct tagtaccaac cgtttgcttc
    13021 ccagaatgct ttcgccgctt cccaagaacc ataacgtgaa gtaacatatt gttctgctac
    13081 tctttcttgg tttgcagcag agtagtcacc atttaagtaa gaagaatcta attggtaacg
    13141 tccgatgtaa cgtccgttcg ttgctgtgta agaaccgctt gattcttttt gtgcgatcca
    13201 ttcttttgca gagcttgtgc ttgctggagt agcagcagtt tctgttacag caggagcagg
    13261 ttgtgtttca gcaacaggcg ctgcttgttt ttccgtttga accgtttctt gtacaacagg
    13321 ttgttcagct tggactggtg cttcttgaac ggctgcttga ggttcagcag ctgcttgtgc
    13381 agagccttct gttgggattg ttaattgttg tcctgagta
//
LOCUS       DAZUJR010000078        13212 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.078, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000078 DAZUJR010000000
VERSION     DAZUJR010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13212)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13212)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13212
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.078"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            147..1016
                     /locus_tag="ACG804_002242"
     CDS             147..1016
                     /locus_tag="ACG804_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFS4833163.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            1225..2250
                     /locus_tag="ACG804_002243"
     CDS             1225..2250
                     /locus_tag="ACG804_002243"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFS4833164.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            2289..3239
                     /gene="manA"
                     /locus_tag="ACG804_002244"
     CDS             2289..3239
                     /gene="manA"
                     /locus_tag="ACG804_002244"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HFS4833165.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIATEPGK"
     gene            3333..5036
                     /locus_tag="ACG804_002245"
     CDS             3333..5036
                     /locus_tag="ACG804_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFS4833166.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKKSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            5038..7071
                     /locus_tag="ACG804_002246"
     CDS             5038..7071
                     /locus_tag="ACG804_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HFS4833167.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            7082..7522
                     /locus_tag="ACG804_002247"
     CDS             7082..7522
                     /locus_tag="ACG804_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFS4833168.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAKTIEEVQMIFEHGHI"
     gene            complement(7722..8849)
                     /locus_tag="ACG804_002248"
     CDS             complement(7722..8849)
                     /locus_tag="ACG804_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4833169.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLPLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(8852..9529)
                     /locus_tag="ACG804_002249"
     CDS             complement(8852..9529)
                     /locus_tag="ACG804_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFS4833170.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            9793..11559
                     /locus_tag="ACG804_002250"
     CDS             9793..11559
                     /locus_tag="ACG804_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol-specific transporter subunit IIBC"
                     /protein_id="HFS4833171.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEALATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            11574..12011
                     /locus_tag="ACG804_002251"
     CDS             11574..12011
                     /locus_tag="ACG804_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFS4833172.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            12024..13175
                     /locus_tag="ACG804_002252"
     CDS             12024..13175
                     /locus_tag="ACG804_002252"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HFS4833173.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
BASE COUNT         4488 a         2293 c         2731 g         3700 t
ORIGIN      
        1 tttataagag tttttactca ttaatttaca aaaaacaagc aaaatgcgaa ttttctcaca
       61 ttttttttaa caaaatcaaa gttattgctt gaaagaagaa gaatccatcg ttaaaataaa
      121 gcttgacgta gaggggagca agaaatatga aagattttca attgggggct gccacctatt
      181 taaaaagtgt agccattcgg gtgaaagacc gagataaaat gattgatttt tacaagaacg
      241 ttgttggctt tgatttgaaa agagaagaaa acgaattagc cattttagga acagaagaag
      301 ctggaagtga aatgttgctg ctggaagaaa gtcctagagc gaatgatcac atgggggtga
      361 tcaaaaagct gaaccgtttt tcattgatta tccctagcac agaagaaatg gcagatatcc
      421 tttgtcgtat ccgtaaaatg aattatccaa tcaaagaagc tttagaagat catggacgta
      481 tggggatttt gctcgtagac ccagaagaga atgaattgga aatttaccat gaagagaata
      541 agaacgacca aagagaaatt ccagaaacaa tggatcaaga agcattatta agaaaatctg
      601 aagaaaaatt cagtaaacta tcaacaggtt cttattttga aaaaatccat ttaaatgtta
      661 ctaacttaac aaaagaacgc caatttctta atcatgtact tggtttgaag gtacataatg
      721 aagaagaggg catccatgta ttgaatgaag gagatttcca tgttggtttg acagaagcta
      781 gcggaggcgc aattgatttg cctacagatg aagtgattgg acttgatttt ctgaaattca
      841 tgatcgatac tgaaagcatg gaaggactga ttgctcactt gcagcaacta tcagttgatt
      901 tcttcttaga caaaaagcac acagtactca caatctatga tgctatagga atcgaatggt
      961 ggttcgtcag tgagccaaaa gaaaagaata aaactgacat tcgatgcgac gcttaacttt
     1021 ttctttctta acgattgtcg catgtctcgt cattttatga acggtcatac tatcgcttat
     1081 tctagagata gaaagagaaa atagtatacc gggggaaact gcgcggtttt tcgcgcagtt
     1141 tttttgtgta aaaaaggttg attcctcata gattaagctt taagcttgga ctgtaagaat
     1201 ctgatagaaa agcaggagaa aaagatgtat ccacacacga aacagcttat tttgaaaaag
     1261 atggaagaag gattttatcc aggtgtagca gtcgccttca taaaagaaaa tcaagtagaa
     1321 acatttacag ccggctttgc ccaagtcgtt cctgaaaagc agctgatgac agaagatctg
     1381 ttgtttgatg cagcctcact gacgaaagtc gttgcaacca cttcattagt tttacgtcta
     1441 ttagaagatg gaaagataga actcgatcaa ccgcttcata aatatcttcc tgaatttgaa
     1501 aatcagacaa tcactttgcg tcatttactg acacatactt ctgatatcaa aacatggata
     1561 ccaaacagag ataagctatc tcaggaagaa ttgatcgccg cttatttgaa gctagaacca
     1621 ggtgagcaac taggaaaaga agtaaaatat acagatgccg gtacgattct tcttgggttg
     1681 atgctagagg aaatttacca agaaactgca gtggaaatct ttcaagaaca agtattggaa
     1741 ccattaggaa tgatgaacag cttatttctt ccttttcctt ccaaaaaaat cgttcccaca
     1801 gaacaactgc cttcgggtga ggttttgcgt ggacaaactc atgatccgaa agcaagagtt
     1861 ttggctgaac atgcaggtaa cgcgggtctc tttattgatt tgaaagacag cattactttt
     1921 gtccaaatgt atttgaacaa gggaaaaatc cgtaatggtc gttttttaga agaagagacg
     1981 attgattctt tactgcaaga tcaaacaccg aaaaaaaatg gctatcgttc tttaggatgg
     2041 gacttaaaaa aggatgtaga agacggtcat gcgattcttt ttcatactgg ttatacaggt
     2101 acgtttttct tgattgatat aaaaacacaa gaagcgttga tatttttgtc aaatcgcgta
     2161 catcctgtcg atcatcgtgc ggagtatctc atatgtcgag atgaaattgt tgaaaacttt
     2221 ttgaaagaga aagcggtatt accgaaataa tgctataata gctatgaaaa atgagaggag
     2281 tttgaattat gcaggaacct atgtttttaa aaccagtttt tcaagaaaaa atttggggag
     2341 gaagtcgttt acgttcagtc tttggttttg atatccctaa cgataaaatc ggagaagatt
     2401 gggcgatcag tgcgcatcct catggtgtca gtgtagtaga aaatggcgaa ttcaaaggga
     2461 aaagattaga tgaactatgg tcagaacaca aggaattgtt tggccatcct tcagaaccag
     2521 tgtttccatt attgatcaag atcttagacg cagaagatga tctatctgta caagtacatc
     2581 cagatgatgc ctatgggatg aaacatgaag gtgaattagg aaaaactgaa tgctggtata
     2641 tcatcgatgc tgaacctggt gcagaaatca tctatggtca tcatgcaaag acaagagaag
     2701 aactagctga gatgatcaaa gatgggcgct gggatgacct tttgaagaaa gtaccagtta
     2761 aaaaaggtga tttcttttat gtaccaagcg gaacgatcca tgctattggt aaaggaatca
     2821 tgattttaga aacacagcaa agttctgaca cgacttaccg cgtgtatgac tacgacagaa
     2881 aagatgcgca aggacaaaca agagagctgc atatccaaca atcgatcgat gtaacaactg
     2941 tccctgcgaa aacaccagaa ttacaaatca aagaagtccg aaaagggaat tcatcgatcg
     3001 tcacttattt agaaactgag tttttcaatg tatatgagtg ggatattaaa ggaatcacat
     3061 ctttcaaaaa acaagcccct tatacattga tgacggtaat cgaaggagca ggagaccttg
     3121 tcgttgacgg aaaaacatat ccattagaaa aaggaacaag ctgtattatt ccaaatggcg
     3181 tttctgagtg ggcggtccaa ggtgaactag caatcattgc gactgaacca ggcaaatagt
     3241 tcccagatag ctgaaagcag cagacggttt ttcgtttgct gctttttcta cataaaatcc
     3301 gtccatcaat aaatagaagt atggtgaaaa agatggaata caaatggaaa gcaaacaaca
     3361 gcagtcgcgt gtctatgaaa caactgagaa aagctggaca tcacttaaat gaaatgatca
     3421 tgccaaatct aagtctgttt atcgcttggg gaatcttgtc attagcaaca aaaggtgtgt
     3481 ctggcgattt gcacaccaca ttagaagagg tatgccattg gatgatccag ctgcttttac
     3541 ccatcttgat cagttattca ggcgggaaat cggtaggggg acaaaaaggg gcagtcgccg
     3601 gtgcaattgc ttctttaggg ttgatcgctc gttccaatgc tccacaaatc gtaggagcga
     3661 tgattatcgg gccgcttgcc ggcatcgtat atgaacaatt tgtttctaga ttccacgtga
     3721 aattcaaggc tggatatgaa atgcttgtca gcaacctact agtaggactg actggtagcg
     3781 ttatttgtat aattggaatc gtttttattg aaccagtttt aaatagtgtt cacttgttgc
     3841 tcgcctccgt tgtgtcttgg ctagtcacaa tgaatctgtt accacttgtc agtctgatct
     3901 tagaacctct aaaagtacta tttttcaata atgcaatcaa tcatggtgta ttgacacctt
     3961 taggaatcga attctcacaa acagtcgggt actcttcctt atttttgatg gaggcaaatc
     4021 ctggacctgg tttagggatc ttactttcta tcctttgttt tgcagaaaaa caggaaaaag
     4081 taaatgcgag tggagcattg atgatccatg cgattggcgg gattcacgaa atctattttc
     4141 catttgtctt gctgcgaccg tatctatttt tagctgtaat ggctggtggg gcaagcggca
     4201 cgttgatatt tcaatggtta gatacgggat tagctgcacc tgtatcgcct gggtcactac
     4261 tcgtgatttt tgccaatgcg ccttatccac aactagctgg ggtaagtata gggatagcaa
     4321 tcagtacatt tgtgaccttc atttgtgcag cgatactatt gaaattacca aataaagaaa
     4381 aagagaacaa aacggtcaaa gaaaggggag aaatcttgga accatctatc attcattccg
     4441 tcatttttgc ttgcgactca ggtatgggat caagtgctat gggagccgcc ctgctgaaaa
     4501 agaaattagc agcagaaaaa atcgatcttt ctgtcggata cagctctatc tatgaattga
     4561 ataaccaagt aaatcagctg gttatcgtgc aacatgaact agcgggtctt gcaagagaaa
     4621 aagtacctca aagtcaaatc tatgtactgg atcacttttt ggaaacagat atcttgctgt
     4681 cacgaataaa agaagcgatc caatttccaa agcgggaaga aaaaaaagag atagcagata
     4741 tcacagaaca aaaaaagtcg cctgctaata ttgtattttt gtataaaaac aacagacgcg
     4801 gctcacaaac tatgggcatg acgattttaa gtcaattagc aaaaaaagcg aaaaaacagt
     4861 ttgttatctc aaaagaatca atagaaaaaa tcaaaatcca agaagaaacg atttatatcg
     4921 cacaaagaga actagctgta actgaacagc tagaagaaaa gatccctcgg ctagttctag
     4981 ttgaacattg ggtagctacg aatgaatacg aaaaactcgt gaagggagaa atataagatg
     5041 tatttatcgc ccagagaaaa acaattatta gcagaatttc tcagtagccc gtcacctgta
     5101 tctatccaaa aaatgatgaa tttattgaag gtcagtaaac ggactattta ccgcgaatta
     5161 gataatcttg aagtctcatt gaaatcggta aatgcttctt tgaaaaaagc agctagaggc
     5221 tcatttgtca ttgaggcatc agaagaagta ttagagcaat taaaagaaaa tacagatggg
     5281 aaaagtaatg acttatccac tgctaaacga caacacgcga ttttagccga gttgttactg
     5341 acgacagagc cgttgagtct tgctcatttc atggaatcat atcgcatcag taataccact
     5401 ttttatgcag atatcaaaca gttggaagaa agtattcgcc aactgccttt ggaaatcatt
     5461 cggaaccagg gatacgagat cgaaggaccg gaaaaatacc gccggcttct gacagcgaat
     5521 gtattagaat tagaaatcaa tgaatatgaa ctttttcata gtatttcttt cgatgcatca
     5581 ctgaattatt tttttcgatt cgttgatccg caacatctat ctcttgcacg caaagtaatc
     5641 ggggaagaat tgatccaaaa aaagaccaat ctaagtgata gaaagcttga acatttggtt
     5701 ttgatgctga cattgacgat ggagcgtgtg actaaaaatc atttactgac aaatgagaca
     5761 tataatagtc tggcaaacaa agaattacta cagacagcta aacgattgtt ttcacggatc
     5821 gcttctgaga caaaacaact ttatccagta aatgagatcg tcttttttgc aggattatta
     5881 aatgacttca cgaactcatt tgatcagaat ttctttgaag agacgttcga tacacagctt
     5941 gcttatttag taaaacaact gattcaagaa gtaagtgaag agacgaatgt ccatttttat
     6001 gaagatgaaa ctttgtacaa aatgctgttg actcatttat ctggtgtgtt ttcaagagcc
     6061 gttttacaag aagagacact gaccaatccg attttagaaa aaatcatggt tcaatacgag
     6121 gaagttgcga atgcaatccg taaagcagta gagcggattt ttcaagaaaa aaaattatcc
     6181 gaagaagaga tcgcttatat ggtccttcat tttgcgaatt cattggaacg aagtccgaaa
     6241 gaaagcaata tcagtattgc aggattttcg ccaagtggat tagcttctac tagcatgttg
     6301 gaactacgat tgaaaaggta ttttcccttc atccaacaaa ttcatttcta tcggattgct
     6361 gatttaaaaa aaatcgattt acaagaagaa tatgatgttg ttatttctac atctatttta
     6421 ccaggatacg gtggaaaata tattttagtc tccccgctac tgctagaaga tgaagtcaag
     6481 cagctaaaag aagctttttc gcatattgag aagaaaaaaa ggcaaaaaat tacgtataac
     6541 agcaataacg agtggatgat agaagatact tatgaggaaa caatgcattt catggatcaa
     6601 atcaatcaat tactcggtcg tttttttatc caagaactgg ataatcctga gacgatttcc
     6661 gaaacgattc gcagcttatt tccttatttt cctgaaggac tagtaacgga tgaagaggtg
     6721 gttcatcgcc ggctgcttaa gcgatatgaa caagcaccta tcggtattcc tcatacaaat
     6781 atggggttat tccatacatc cagctcattg atttctaaac cgatcttttg tattttcaat
     6841 ttgaaacatc cgttgaccat tgaagggatg gatagacagc cagtcgattt gtcccgtatg
     6901 ttagttatgc tggcgccttc gccaatccaa gaaaaagacg ggattctttt aggaaagatc
     6961 agtggagcaa tcatcatgaa tgacttgaac accgagatct tccgctcagg aaataaagaa
     7021 atcgtttatc agttgttagc gaaaatcctg attgaagaaa taaagaaatg aaggtgaaaa
     7081 gatgatacag ctaccagcag aaaaaatatt gctcgatcaa tcctatcaaa attggaaaga
     7141 agcgttgacc gagatcggcc agtggatgac ccaacaaggg ggaatcaaac cggcatatat
     7201 ccaatcaatg atcgaaagac aagaaaaagc gagtgtctat atcgggaatt tcgtagcctt
     7261 gccacatggg actgacaaag atgaagaagt agtagaagaa ggaatctatt tagtccaagt
     7321 gcctgatggt gtggactttg gaacaaaaga ggaaccaaaa atcgcgacac tcttatttgt
     7381 agtggcttta aaaaaagaac atcagttagc ggtgctccaa gatttagcct ttttctgttc
     7441 agacatcgac caagtaatgg cgctcagtga tgcgaaaacc attgaagaag tccaaatgat
     7501 ttttgaacat ggacatatat aaccaatgtt cacagtaaaa aaagctgcct tgcatcaagt
     7561 aataacttca accaagataa aaataagagg agctattttt gttgggaggt tcttattact
     7621 gcggatgcaa gcttttgaaa actatttatt ctagaaaacc gtttatttga aataggggac
     7681 ggtgacaagg tttttgtcac cgcccctatt atttttgtgt tttaatagct cttttttata
     7741 tagatagtgc ccatacctat gaataataaa acgatactcc atataccaag tgtcaagata
     7801 ccattcatga aagtaacctg ttctgaagct agtggcgaga aaatatctcc tcctatgatc
     7861 acattttgaa aatcaacata agaagttggc aagtaatgac tgattgattc tatccatcca
     7921 atcgaagaaa acaagcgata ctctgctaag aaaagacaaa gaagtgtacc taaaagattg
     7981 actagagaat gttcaaataa agcagataga agaaaactga ttgtacttaa aaagagcacc
     8041 cacaacaaca ggaacagaaa gctctggaaa agatactcat acatcggaag gattcgtatc
     8101 tcctgaccaa tgatcgttcc tacaggataa cggaagtctc ccaaaccatt tttgattatt
     8161 actagtatag agacgatcaa aaatggcatc acgagactta gcatagctgc accataataa
     8221 atggtaaaac ggatgctatg tttctttacc atactatccg gtaatagatt gactagagag
     8281 attacctgct ttcttttttc ataagagatg atggaagaaa gaaacaaggc ggttatacat
     8341 aaaatcaaaa aactagaaat cattcctgaa aaaatatttt cgtagtaatt tgctaaaggg
     8401 agatgcgctg gcaagtcaaa aatagaatat ctttggatct gatgttcttt catataacgg
     8461 agcaactcga cacgtttttg ttgttcaatg attggaattc cttgtctttg accagaaatc
     8521 agtcgatcca gtatatcttt ttcataatga taagttgctt cgaccatttg ctggacattc
     8581 cctgtgtttt ttgcatgtaa gattgcttcg atcagtttgt tgcttttctc taaactttcc
     8641 acaaattctt tctcattctc atcttctttc aacgtttcaa tcaaacgttg catctcttca
     8701 tagttatgat tcagttcatc gaattctgta taagcaagtt tatgatcaaa aaaaagtggg
     8761 aatgcaaaga gcacgaccaa caatagagga aataaaaagt ttactttgtt ttttagtaag
     8821 agattgcgtt caaatgtaag taaagacata gttacacctc atataattta cgataaatag
     8881 ctaaaatctc ttccatattt gaggattctg tgacgatttc tccatttttt agaaaacatg
     8941 ctttagaaca aatcgattgg atattcgcga tagcgtggga agaaagaaga atcgtcttcc
     9001 cctctttctg ccattgtctg atgaggctat tcaagatatc aatacttcct gggtctaatc
     9061 cgttcaacgg ttcatcgaat aacatgacag atgaatcact gatcaagtaa gcagcaagca
     9121 agacatgttg tttcattcct agagacattt ttccaatcgg caaagtaagg tactcagtca
     9181 tcttcaatcg ttggaaaaca gtttggcatt ctactttgct ctgccaatag tatttgatca
     9241 aagtcaaata atcaacagcc gatagatagt cggataactg attcgttgat tctagaaaaa
     9301 agaaagaccg gcgataatct gtataagcag taggagagat gttgtgaagg gacaattgat
     9361 cataagttgt tggcagcagt tgggcaatgc cattcagcaa agttgttttg ccaaatccgt
     9421 tcggggcaat caaagcagct acttctcctg attctactaa aagattcaat tgtcgaatca
     9481 cacgtttttt accacgtttc atgttcatgt ttttgatcag taatgtcata gataggcctc
     9541 caatataaaa tttaataaca taatagaatg gaaaacatct aaattaaatg ctaacaaaag
     9601 ttattgtttg catattataa aaaaattaaa ataacagttt tatttaaaat tgaagttttc
     9661 tgataccgaa atctttttat tttgctgaca tactcaaacc tttggcacaa agtttcgtgc
     9721 caaagtacga ctatttctct ttttagtaag cggatacaat tagagtatca aaaggagaga
     9781 gggagagaca aaatggaacg gacgattccc aaaaacaaca tttcgctaaa agcgagggta
     9841 caaaaattag gcagtacttt atcaagcatg gtcatgccaa atattggagc actgattgcc
     9901 tggggtgtat taacggctct atttatccca gatggttatt taccaaatga ggctttggct
     9961 accatggtaa gcccaatgct aacttatctg attcctttat tgatcggtta tactggcgga
    10021 aaagtaattg ctggtgaccg cggatcagtt gttggggcaa ttgcaacgat gggtgtgatt
    10081 gtcggaacag atattccaat gatgctaggc gcgatgatca tgggacctct tggtggatat
    10141 gccatcaaga aatttgatca gctattccaa aaacggatca aatccggttt tgaaatgcta
    10201 gtcaataatt tttcagcagg tcttatcggt tttggattag cgttattagg tttttctgcg
    10261 attggtccag ttgtcgatgc attgactcaa gcaatggcaa aaggtgtaga gatcatttta
    10321 tctgcccatt tgattccatt gacaagtatt tttattgaac cagcaaaaat cttatttttg
    10381 aataatgcaa tcaatcatgg gattttgaca ccattgggaa ctgaacaagt agcagaggct
    10441 ggaaaatcta ttctattctt gcttgaagca aatcctggtc caggacttgg cgtattactt
    10501 gcttttactt tgtttggcaa aggagcagca aaatcttcag caccaggagc catgatcatt
    10561 cactttttag gcgggatcca tgaaatctat tttccttacg ttatgatgaa accgttatta
    10621 ttcttatcag ttataggcgg aggaatgtca ggaagtttca ttttccaatt gatggatgct
    10681 ggactaagag cgccagcttc tccagggtcg atcattgcga ttctagcgat gacaccgttc
    10741 aattcttacc ttcctgttat tttgggcgtg attgttgccg cagctgtttc gtttggtatt
    10801 tctgcagtaa ttttgaaagc ggatgcgaaa gatacaaatg aagacttcga aaaatctgtt
    10861 caagagacaa aggcagctaa gcaagcttcc aaaggtgccc aaggtattcc tcaaggagct
    10921 acattctctg gcgtacaaaa aatcattttt gcttgtgatg caggaatggg atcaagtgcg
    10981 atgggcgctt cgatcttgag aaaaaaagta caggaagcag acttgcctca aacggtgacc
    11041 aatcaagcaa tcagccaact gacagatgac tcgaatacat tgatcgttac tcaggtcgaa
    11101 ctacaagaaa gagcaaaaca aaaagcaccg agcgcgcgtt ttgtctcagt agaaaacttt
    11161 ttgaattcac ctcgatatga tgaaatcatt caagaattaa gcagcaagca gaaaacatca
    11221 gtttctgaaa ttgagaatga gccagcagaa gagtttcttt cagcaaacat caaacaaatc
    11281 aaagagattc tacttgtcca cgatgatcgt tccggatcag caacaatggg gatgaccgtg
    11341 ctcaaagata tattagacaa gaaccattta actatcccgt taagaaaagt caatatccaa
    11401 gatttaaaag atgaacctga ttcactgatc gtagccaaag aaagtttagc ggaaaaagta
    11461 cagatggctg cacctcaatc cattcattta tcagtcaaca gcatggtcaa tccgcaaaaa
    11521 tacgaatcga ttgcacaata tttgaaacag acagcttaag ggaggaaaac agcatgcaaa
    11581 gtttgccatt cgacatgatc gagctcaatc gatcttttaa aaccaaagaa gaagcgatcc
    11641 gctattgcgg tcagatgctt gtagaagcag ggtgcgttga tgaggaatat atcgatgcca
    11701 tggtagatag agacaaaatg ttatctgttt atatggggaa ttttatcgcg attcctcatg
    11761 gaacagatga agcaaaaaaa tatgtgaaaa aatccggcat ctgtgtcgtt caagtaccag
    11821 atggtgtaga ttttggtacc gaagaagaag aaaagattgc gactgttttg ttcggtattg
    11881 caggagtcgg agatgagcat ttgcaacttg tacagcaaat cgcactttat tgcagtgata
    11941 tggacaatgt tgtccagcta gcagacgcgc tcagcaaaga agaagtaacg gaaaatctag
    12001 caattgctta aggagagaga aaaatgagag cagtacattt tggtgcagga aatatcggtc
    12061 gaggatttat tggagaggtt ttggcagcta atggatttga gattactttc gtagatgtga
    12121 atcacacgat cattgatgct ttaaatgaaa gaaaagaata cgaaatcgaa ttagcagatg
    12181 aatcaaaaga aaaaatcact gtaaaaaatg tcaaaggaat caacaatcaa acaaatccag
    12241 aaaaagtaat ccaagaaatc gctgaagcag atttagttac taccgccatt ggcccgaata
    12301 tcttaccttt tattgctgag ttgattgcaa aaggtatcca agaaagagaa aaggaaggaa
    12361 gcacaacatc tttagatatc attgcctgtg aaaatatgat tggcggttca gcatttctag
    12421 aaaaagaagt gtataaatat cttccggaaa catcatttac tgacaaatat atcggctttc
    12481 caaatgcagc agtcgatcga atcgtcccat tacaacacca tgaagatcct ttattcgtcc
    12541 aagtggaacc tttcaaagaa tgggtcattg acgatagcca aagaaaaaat aaaaaaatcc
    12601 aattaaaagg ggttttatat gtagatgatc tagaaccata tatcgaacgc aaactattta
    12661 gtgtcaatac tggtcatgcg actgtcgctt atacaggtgc cttgttaggt taccagacca
    12721 ttgatgaagc aatgcaagat gcgttagttg tggcacaatt aaaatcagtt ttgcaggaaa
    12781 caggaagttt gctgattgcc aaatgggggt ttgatgcaga gcagcatcat gcgtatattg
    12841 aaaaaatcat tcatcgcttc caaaacaaaa atatctctga tgcgatcaca cgtgtcgctc
    12901 ggacaccatt acgtaagtta ggttatcaag aaagatttac acgtccagtg agagaactac
    12961 aagaacataa cttgacttgc ccacatttga cggcaacaat ggggattatt tttaattact
    13021 atgatcctga agatgaacaa agccgtcaat tgcatgaaat gaagatccat gaaaacttgg
    13081 aacaattgat tcaagaagtc acaggaatca atgatccgaa aacaatcggg aatatcaagc
    13141 aaaacgtgaa ccgttatgcc aagcaagtcg cttaaaatag gatacgaaaa aggggaatgt
    13201 gacgaaattt tt
//
LOCUS       DAZUJR010000079        13084 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.079, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000079 DAZUJR010000000
VERSION     DAZUJR010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13084)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13084
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.079"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(78..2198)
                     /locus_tag="ACG804_002253"
     CDS             complement(78..2198)
                     /locus_tag="ACG804_002253"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFS4833174.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLAKGKNVIYIHLESFQQFLIDYKLTDENG
                     LQLEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHKG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2428..3606
                     /locus_tag="ACG804_002254"
     CDS             2428..3606
                     /locus_tag="ACG804_002254"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HFS4833175.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIVGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3622..4380
                     /gene="aroD"
                     /locus_tag="ACG804_002255"
     CDS             3622..4380
                     /gene="aroD"
                     /locus_tag="ACG804_002255"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HFS4833176.1"
                     /translation="MVWVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLAGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4403..4888
                     /gene="ybaK"
                     /locus_tag="ACG804_002256"
     CDS             4403..4888
                     /gene="ybaK"
                     /locus_tag="ACG804_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_process: GO:0043039 - tRNA aminoacylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HFS4833177.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSHIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4959..6212)
                     /locus_tag="ACG804_002257"
     CDS             complement(4959..6212)
                     /locus_tag="ACG804_002257"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFS4833178.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6328..7677
                     /gene="gdhA"
                     /locus_tag="ACG804_002258"
     CDS             6328..7677
                     /gene="gdhA"
                     /locus_tag="ACG804_002258"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HFS4833179.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNAQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7789..9135
                     /locus_tag="ACG804_002259"
     CDS             7789..9135
                     /locus_tag="ACG804_002259"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HFS4833180.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9443..9829)
                     /locus_tag="ACG804_002260"
     CDS             complement(9443..9829)
                     /locus_tag="ACG804_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFS4833181.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYTEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
     gene            complement(10097..10246)
                     /locus_tag="ACG804_002261"
     CDS             complement(10097..10246)
                     /locus_tag="ACG804_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833182.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            10708..10920
                     /locus_tag="ACG804_002262"
     CDS             10708..10920
                     /locus_tag="ACG804_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833183.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPTELVS"
     gene            complement(11198..12997)
                     /locus_tag="ACG804_002263"
     CDS             complement(11198..12997)
                     /locus_tag="ACG804_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HFS4833184.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRSFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
BASE COUNT         4291 a         2353 c         2577 g         3863 t
ORIGIN      
        1 tattctaaga tttctcttta ccaacatcat ttgacaaaga gcctaatttt gtcgctgctc
       61 cttttaaatt tattttatca ttcggaagaa cttgtggtcg ttccgtgaag ttcttggtac
      121 gtttgcgttt tataaagatc aacagttgat tgtcccttgt gttcactaaa gacactagtt
      181 gacttgtcac caagagattt ttcagcttct tttaatttct ctaagccatt cttgtagtca
      241 taatcactgg tatcaattgg gtctaatcca ctattcgtat agaaccgaag aagatcacca
      301 ttattgattt ggtcagaaac agctaactgt ttatcaactt tttctttcag tgaatcaatt
      361 tcattctgta cttcctcagt aggttcagta atagcttcac cagtttcgtt actatagatc
      421 gtaccaccgt agtaagtata ttttggtgta acaaaatcac catcacggaa agaaacaagc
      481 tgttcatgat ctttcgagaa tagatcttgt cctaactgaa tataattttt tgtatctaca
      541 cctagtaagt gaagtaatgt aggcaaggca tcaacttgtc cgccgtaagt gtgattgatt
      601 ccgccctgtg tttgtccagg gatatggatc atataaggga cacgctgcat ttgtgcattg
      661 tcgtagtttg tccaagtaga acttgttttt ccaactaatt cagctagatt tttatttctt
      721 gaattcgaga caccgtaatg gtcaccgtaa aggacgatga ctgaattatc atacaagccg
      781 ctttctttca aataattgaa gaattcttgt acggcggtat ctaaataatt ggctgtcgca
      841 aagtaaccgt tgatcgtttc atcatttgta ttggctaacg ggaatcctgc ttcgtcattg
      901 gtgaattttg aataaggata atggttagat acagcaatga attttgaata aaatggttgt
      961 tgcagacgtt ccaagtattg tacggattgt tggaaaaatg gtttatcatg caacccgtat
     1021 tggaacgaat tgtcatcatt aacatcataa taagaagaat caaagaaata atcatatcct
     1081 aaattcttgt atgtctcgtt tcgattccag aatgtaccag cgttcccatg gaataccgca
     1141 ctagtgtaac cttgtgtttg acttaaaata tcaggtgcag cttggaaagt attttttccg
     1201 cctaattgtg tgaacaagga gccttgattc aagccaaaca atgaattttc catcagcgtt
     1261 tccgcatcgc ttgtttttcc tgcttttact tgatggaaaa agttgtcaaa actgaacgtg
     1321 ctgttgctgt ggtaaagact attgatgaaa ggtgtaactt caagctggag accattctca
     1381 tctgtcaatt tataatcgat caggaattgc tggaagcttt ctaaatggat ataaatcaca
     1441 ttttttcctt tagcgagccc gaacaaatca tcatttggtg ctgcataatg ttcttttaca
     1501 taattttcta cttctttcat atcattggga cttgcttctg cccgcacttg gtttgtctgg
     1561 taagtttgaa caccgtcata aaccatgaaa gcattcaagc caagatattt gaccaaataa
     1621 tcacgagaga atgttcgagt cagcaattct ggacgatcag cttccgccat aaaaagattt
     1681 cctgagaaaa tcataactgc taatgtagag atcgcaaaag ccattcttgc tcggatcggg
     1741 cgagggtcca acttgatttt ttttgcaatc agcagaacag tcaagataat aaaatcgatc
     1801 caatagatca catcatatgg gcgaaacagt cgaatggcac tttctcccag accactcgct
     1861 actttcccag cacctaaaat cgtgttgatc gtaatgaagt ccgtgaattc tcgataataa
     1921 gtgacattcg aaaaaacaag caatgtcaaa agaaaataaa tgaccatcat cgtgatataa
     1981 gcaactctag ggcgtctgat ataaagagca attccaagta ataacaatgt agttgcaata
     2041 gggttgataa acaagataaa gtattgaatg ccactttcga ttccgagatg gaaatcaact
     2101 aaataggcaa aaatcgtttt caaccaaagt aaaacaacta gtaaagaaaa aaatccgagc
     2161 ctcttattca aaaaggcagg tgtttttata catttcaaga taatcttcct ttctgcactt
     2221 cttaatcaca gaagtgtcat gaaaccatgt tacacagctc acttattctc atttatttta
     2281 ctagtatgac aatatagtgt caattgaaac cagaagttta tgctgtttca ttaaggtttt
     2341 ctttaagctt catgaaaaaa tgagcagtaa gacaagtcct atgttttttg ttatacttgg
     2401 gaagagaaag ctaaagcagg tgaaggaatg aaagtaaaag taaaaaaaag agcaagcaat
     2461 cgattgaaaa aaggatatcc actgatccaa aaagaagacc ttgctcatcc ccaaaaagaa
     2521 accacgcaat gggtggaatt agttgattcg caaaaccaat ttatcgcaaa aggatatcta
     2581 ggaaagcaga ataagggaat cggttgggta ttgagccagc agaacatccc atttgatcaa
     2641 tctttttttg aagaattttt tgtgaagtca aaagaaaaaa gaactttctt tttttcagat
     2701 gattctacta ccgcttttcg tatattcaat ggagaaggag acgggatcgg cggtctgatt
     2761 gttgattatt atgcaggtta tgctgttttt tcttggtata acgaaacgtt atatgcacat
     2821 cgtgaattat tgattcaagc ttttcgtgaa atctacccgg aaatcgtagg aggctatgag
     2881 aaaattcgat ttgaatcagt aaatctgcct gagagccagt tcatttacgg aaaagaggca
     2941 ccggaaccct tgatcgtaaa agaaaacgga gtaaaatttg ccgtttattt aaatgaagga
     3001 ttaatgactg ggatcttttt agaccaaaaa gaagtacggg gatcattagc agaaggtttc
     3061 gcttctggga aaacagtttt gaacatgttt agttataccg gcgccttttc tgttgctgcc
     3121 gcaatgggag gggcaatcga aacaacaagt gtcgatctag caaaacgcag tttaaaaaaa
     3181 acacaggaac agtttgaagt gaatggtttg gatgtcgatc agcaaaaaat cattgttatg
     3241 gacgtattcg agtatttcaa atacgccaaa agaaaacaat ttttatatga catgattgta
     3301 ttggatccac caagttttgc cagaaataag aaaaaagtct ttcgcgtagc aaaagattat
     3361 ggggaactgg tcaaggatag tctggatatt ttagcagaag acgggatact tattgcgtct
     3421 acaaatgctg cgaatgtctc gatagaacaa ttccaaacaa tgattgaaga ggaattccat
     3481 gccaaaaatg tttcttttga acaacttgct ttatatcgtc tgccaaaaga tttccagacg
     3541 acggatacct ttttagaagg caattatctg aaagtgtttg tttatcaaat taaaaataac
     3601 cattagaagg agcgatgcag aatggtttgg gtaaagggat tgaatatagg aagcggtaga
     3661 ccaaagattt gtgcgcctct tatcggggcc gtccgagagg aagtattacg tgaagcagtt
     3721 cttgcacgtg aagcaggggc cgatttagtc gaatggcgag tcgatcatta tcgtgaagtt
     3781 ttttcttttg atgaagtagc agaaacattg gttcttatcc atgagatgct tgatggactg
     3841 ccgttattat ttacgtttcg taccttagct gaaggcggag aacaagacat atcgatccgt
     3901 cagtatcgcg acctttatga acatgtgata cacacaggat tagtagatat ggtcgatatc
     3961 gagttgttca aagtagaaag tctaggaaaa agactgatag aggaaatcaa gtctttaaac
     4021 attcctttaa ttatcagtag tcatgatttt aaagaaacac cagcagaccc tgtcttgctt
     4081 taccgattga atgttatgga acattttgga gccgatatcg gaaaactggc agtaactccc
     4141 aataatgaac gagatgtttt gcggttgatg gagttgacta gacgggcaaa tgcttttgtc
     4201 tccatgccta ttattacgat gtccatggga aatcttggta aaatttctcg tctggctggc
     4261 ggaacgacgg gttccgttat gacatttggt tccttaagca gcgattctac ttctgctcca
     4321 ggacaattac cggtcaaagc attgaagcaa attattcaat tattaaatga accgttgtag
     4381 aacaagtttg aggtgatatt ttttggcaaa gaaaaaaata gtaaaaacga atgcaatccg
     4441 tatggtcgaa caaaaaaaga ttccctatac agagcacgaa tatgagtggg acgaaagcca
     4501 cctaagtgcg tcatcggtcg ctgaacagct tccagaaagc caatctcata tatttaaaac
     4561 actggttgct gtgggcaatg tgacggggcc tcttgttgct gtgataccgg gagaagccga
     4621 attgaatcta aaaaaattag caaaagtttc agggaataaa aaagtagaaa tgctccattt
     4681 aaaagatttg gaagcaacga ccggatacat acgtggtggc tgctcgccta taggtatgaa
     4741 aaaactattt cctacttatt tagatcaaat tgcagaaagc tatgaacaaa tcattgtctc
     4801 ggctggcaga agagggctac agatggagtt agcacctcaa gatatctgtg cattaacgag
     4861 cggacaattt gcagatataa aacaataaat catacgtata aaagaaagaa ggaggccggg
     4921 atgttgtttg tccagtctcc ttctttcttt tttatacatt atgctctttg cccggcattc
     4981 attcctgcta catgccctgt agcgaaagcc gctgtgatat taaagccgcc agtataacca
     5041 ttgacatcca gtaattctcc cgcaaaatac agaccatcaa tgattttact ctccaatgtt
     5101 ttaggataaa tttcctttag agaaacccct ccgccagtta caaatgattt ctcaatagga
     5161 aaagttttgt tgattgatag cttaaactct ttgcatagtt gaacaaaatc ttgaatttgt
     5221 ttttgagagg cttgttgtcc tgtcagatga tccatttcaa gccgctcaag aaagaaaact
     5281 aacaatcgct caggcaatat accatgccaa gcattgacca agttcttttt ggttgcttta
     5341 cttttttctg tcaatatatg aataagctct tgtttggttt gtgtagggaa acaatccaga
     5401 gaaagtgtca ctggttctcc cgttttctct aattctttat tgacaaaact tgaacaacgc
     5461 agtgcagccg gaccagaaat accgaaatgg gtgaaaagta aatccatcgt atgttcagtc
     5521 aatacacgac cttttttatt taaaacgcgt aaagtgatgt cttgtaaaga aagcccttga
     5581 agtgttttct cctgaatata cggttcatcc gatatcaagg gggactctgt cgcataaaga
     5641 ggcgtcaccg tgtgacccac tcgcttcacg atcttgtacc catctccagt agaaccagta
     5701 gatggataag tccgtccacc agttgttaag ataatggcag gagcatggaa ctcttcgaat
     5761 tccgtgcgta taccgtaaat tttatgttct ttgtggatca atttctctac tcgagtagag
     5821 aatagaagcg tcacatctag ttctttcaga cgattgagca atgcttcgat aatcgttttt
     5881 gatttatttg ttacaggaaa catccgtcca tgatcctctt cttttaaatg tacgccttgt
     5941 gattcaaaga agttcatgat atcgaaatta ttccattgcg caaacgtact atataaaaac
     6001 tttccatttc caggaatatg tgcaatcaaa tcatcaacag gacgattgtt cgtaacattg
     6061 caccgaccac cacctgtcat cagtagtttt tttcctgctt ttttgttttt ttcgatcaag
     6121 agtacgcgtg cgccttgttc agctgcactg atcgctgcca tcatcccgct tgttccagcg
     6181 ccgactacga tcacatcata cagtttttcc attccctcac ctcaaggaaa gtgtagcata
     6241 tctgaagaaa gaaaacagaa aaaatgtttt gagccaaaag agaaaatgag ctaaaatgag
     6301 ggaagataag caaaggagcg tggaacgatg acaaacgcaa cagaatatgt tcaagcaatt
     6361 caagaaaagc tacatcaaaa ggatcaaggg caagaagaat ttttacaagc aatcgatgaa
     6421 ttcatgccca cggttatgtc ttttttggac actcatcccg aatatatcga aaagaatatc
     6481 ttagaacttt taacggaacc agaaagagtt attcaatttc gagtgccttg gcaagatgat
     6541 gaaggaaact ggcgagtaaa tagagggtac cgtatccaat acaactcagc tatcggccct
     6601 tataaaggtg gattgcgctt ccatcctagt gtcaatctaa gtatcttgaa atttttggct
     6661 tttgaacaga ttttcaagaa tagtttaacc ggtctgccaa tcggtggagg aaaaggcgga
     6721 agtgacttcg atcctaaagg aaaatctgat aatgagatca tgcgtttttg tcaaagtttc
     6781 atgctggaat tgtcaaaaca tatcggccca tcgattgatg ttcctgcggg agatatcggt
     6841 gtaggagcta gagaaatcgg ctatttgttc ggcgaatata aacgattgaa aaaatatgat
     6901 actggtgtgt tgacaggtaa acctttggat ttttggggaa gtaagatacg tacggaagct
     6961 actggttatg gattagtgta ttatgtcaaa catctattga acgaagaaaa agattcattt
     7021 aatcaaaaaa cagtttttgt ttccggaagc gggaatgtag ccatttatgc aatcgaaaaa
     7081 gtgcaagagc taggcgggaa agttgttaca tgttcagatt ctagcgggta catctatgat
     7141 ccagaaggaa tagatgtgaa actattgaaa gaagtcaaag aaatcaatag acaacgtttg
     7201 acggaatacg caaaccaacg tccttctgct atttatcatg ctggagaatc tgtttggaca
     7261 ttgaaagaaa aagcggatat cgctttgcca tgtgctactc aaaatgaaat agacgaaagc
     7321 ttggccgaaa tcttagtaga aaatgggatc aaaatcgtag cagaaggcgc taatatgcca
     7381 tgtacagtaa aagctgtttc tgttcttcat gaagcaggcg tgtggtattg tccaggaaaa
     7441 gctgctaatg ctggaggagt agcagtatct gctttagaaa tgagtcagaa cgcccagcga
     7501 ttgacttggg aaagagagca agtggatgag cagctggatc aaatcatgga aacgatttac
     7561 catacgtgtc gccaaacagc agccgagtac ggcgacgaaa aaaatctgct tcttggagca
     7621 aatgttgctg gatttgaaaa agttgccaaa gcaatggcag cagaaggttt agtttgaaaa
     7681 atgaaacttt cttggaaata ttgtcagcat tttgtttatt tgcttgaaaa ataataaaaa
     7741 aaaacgtaaa gtattacctg tagagtaaac ctataaggag gagaacaaat ggcacacatt
     7801 cattttgact attcaaaagt agcaccgttt gtcaacgaac aagagttagg gtacatgcaa
     7861 agccaagtaa cagcagccca caacgaatta cgggaaggta ctggcgcagg aagcgacttc
     7921 cgcggctgga tcgatttacc aacgaactat gacaaagaag aatttgcacg tatcaaagaa
     7981 gcagctaaaa aaatccaatc tgattctgaa gtattagttg ttatcggtat cggtggttct
     8041 tatttaggcg ctcgtgcagc gatcgacttc ttgaatcaca cattcttcaa tttattagat
     8101 agcaacacaa gaaaagcacc acaaatcttc tttgccggaa attcaatcag ctcaacatat
     8161 attgctgact tgatcgaagt aatcggtgat cgcgactttt cagtaaacgt tatttcaaaa
     8221 tctggaacaa ctactgaacc agcgattgcg ttccgtgtat tcaaagagct tcttgttaag
     8281 aaatatggac aagaagaagc aaacaaacgt atctacgcta caacagataa agcaaaaggt
     8341 gcagttaaag tagaagcaga tgcagaaggt tgggaaactt tcgtgattcc tgatgacatc
     8401 ggcggacgtt tctctgtatt aactgctgtt ggtttgttac caatcgctgt tagtggtgca
     8461 gatatcgatg cattgatgca aggtgccgct gatgcaagca aagcatactc aagcgacaaa
     8521 ctagaagaaa acgaagctta ccaatacgca gcaatgcgca acattcttta ccgtaaaggc
     8581 aaagtaactg agttgttgat caactatgaa ccaggaatgc aatacttctc agaatggtgg
     8641 aaacaattgt atggtgaatc tgaaggaaaa gaccaaaaag gcatctatcc ttcaagcgca
     8701 aacttctcaa ctgatttgca ctctttagga caattcatcc aagaaggacg tcgcaatatt
     8761 tttgaaacag ttgtgaaggt tgaaaaacct cgtaaatcaa tcacaattcc tgaacaagca
     8821 gaagatttag acggtctagg ctacttgcaa ggaaaagaag tggacttcgt aaatacaaaa
     8881 gcatttgaag gaacattgct tgctcataca gacggtgacg tgcctaactt gctagtcaaa
     8941 attccagaaa tggatgctta tacattgggt tatacaatgt acttctttga aattgctgta
     9001 ggtatttcag gttacttgaa tggaatcaac ccattcgacc aaccaggtgt agaagcttac
     9061 aagaaaaaca tgttcgcact tctaggcaaa ccgggctttg aagatcttgc taaagaattg
     9121 aacgaacgcc tgtaagataa gggtttttcg ctagatttaa ataatcagtg atagaaacat
     9181 gttcgcttta aaatgaaaac tggtacccat ttaggtactc aaacatactg catcgtttat
     9241 tcagaataag gggctgtgac aagacgtttg tcacagtccc ttgtttgtat agaaatcgat
     9301 tgattgcctt gctctttagt ttgttttagg actttaagaa cagtgaggct gacttcgaag
     9361 gttaattctg tttttttgtt ttctagaatc agtaagcaaa aaagcactca cttcgagtgc
     9421 ttttttgcga tatattctta gcttaagata ggcctaattt ttcttttaca gatgagggta
     9481 ccttatcgct ggtaattact tttttctcta tgatccgctt ttcgcttgct ttcaactgca
     9541 agatcgttcc ttcggtgtaa gcagaaccat tggcagagtc accagaagta atgacatcga
     9601 aatctaactg tcttttttca ccgttttcag cataagcatc tacgttgtat ttaaaacctc
     9661 ttccaattac ttccccatta tctgctttga tatcagtttc tgcaggcatt ggagctttga
     9721 ctaccgcata ataatcttta cctacataag tagactgata gtagtcccaa cctttccatc
     9781 ctataaaagc aatcaatatg ataacgatca accctaaaat ttttttcatg aaagatctcc
     9841 ttttttattt ttattatatt aaatattata cagataataa cggaatatta tcatcgaaac
     9901 agctaacaaa attgtcataa aaaacgagat ggttgatatt agaacttgtg tttttgttta
     9961 ggtctagaga taaagagaga caatttccaa atatatgtaa tgaatacaaa aagacgtttg
    10021 tcgcggatta ccgttacaaa cgtcttttat tgattttccg agatctcatc agtcgccatt
    10081 tggaatggtt cactccttat ctagattcgt ttaatgctcg gactgcttgt tcgattgtaa
    10141 taccaaacgc aacgttattt tcgttttgtg catcaatcgc cataaaacgg ttagaagttg
    10201 tatcaaaagc tacgcggtat tgcatatttg tttttgtaaa cgtcataaaa ttcatctcct
    10261 ttgtaatgta atttagttct tgaaagtttc ctttaaactt tcgaacttat accaagttta
    10321 gcatcgtacg ttttttgatg caattaaaaa gcatttatca ttttccttat ttattttttc
    10381 ttaaatggtt tagctatttt cttttaatcc gataagtagc ccaatcatca aggttacaaa
    10441 tactattgct tgaatataaa tcatatgctc acctctttat aaataactta gcaatataaa
    10501 gaaaaaaacg cacgaacaac ataggaatat aaacaaacgt ttttgtcaca acgtctaaga
    10561 tcgtgttaaa aaatagttat ctaaaaagca gaaagatact caaaataaaa aataaaaaaa
    10621 tgaataaaaa cgttttcaaa tacaaggtaa tttgttatta taaaataaag aaaaaacaaa
    10681 ataaaaataa agaaaagagg gaatgaaatg gtaaaagcag aagtaggaag atcttatata
    10741 tgcaaaccga tcggagtatc tcatgaacta atcggctgta ttgaacgtac atatatcaac
    10801 acggctgtcg tgtatgttga aagttatgac caacgagact atcaacttat caatgaaagc
    10861 aagtatcgca tgctcgtaaa attctgtgat attagcgcac ctactgaatt ggtttcttaa
    10921 acagtatttt tgagaattcg caagaactcc cttataatat aaataaagac agaagggagc
    10981 gagaagatat gccaaaaaga aaaagttcag ggaaaatggg aattattctt gcagtgatct
    11041 ctgcaattcc tgctatttta gctattgttc gtgcgatgaa ggaatcaaga gaaagttaag
    11101 cacacattat gagcgtcaaa caaaaaacgc atatacctgc ggtggcaggt tatgcgtttt
    11161 ttgttgtata aagacttttt tcattaacga tttttgatta gccgactccc aaaacaaaat
    11221 ttagcagttt atctgaataa gtgatttctt catctgtttg tttcacactt tcatttagta
    11281 gtcccatctc atcggttatg ataccatcca caccataaaa catcatgcga ctcatggcat
    11341 ctgaatcgtt gattgtccat acatatactt cttttccgtc ttggtgggca gaattaatga
    11401 agttacggtt gatcgtacta tattccattg tcagaaaatc agcaggcgtc acagggggcc
    11461 caacaatatt gaaaggtaag atgtagccca cataaaagtt tggttctgct tcttttaaat
    11521 ctgaaacggt ttggtacgtc aaactttgca aaatatgatg gttctctaag ataactttgc
    11581 ggtatttatg gacaaatcgt tcgacaaggt catccgaatc ttttttagag gtcttgatct
    11641 caataagtaa tttttggttt agcttatgtg ctttttccaa ataagaatca aaagaacaaa
    11701 caggggcttg cactccgttt tcagtaactg taagatttgt caattctttc aatgtaagat
    11761 cctgtggtgt tccatttacc cctgttaagt gacgaagatt tgcatcatgc atcactacga
    11821 aatgaccatc ttttgtttcc tgaacatcca tctctacata atcaggatga tagtctctgc
    11881 ttgttttttc aagtgcttct aaagtatttt gcgccccatt ttgggtactc acacctctgt
    11941 gagagacagt cactggtttt gtctgaacag ctgaagtcag ataatccata ttgtaaagac
    12001 agacgccaat accgaaaaaa actgcaaaaa gagtcaaacc agtgtttttc agcgcagaga
    12061 aacgcaagtt gggggcttgt gggataaacc acttagggat ctcaggcaag aagccttcgt
    12121 catccatgaa atcaacaatg atataaaaaa tccctacggt agacatcacg atattgaata
    12181 ataaaatccc ttgtaaaagc gtcatagcaa acacagcgct gatcaatgca tagtctggga
    12241 aaaattgttc aaccatactt tgtgccaaaa taacaacgat atatcctaaa gaagaaagga
    12301 gtaaaatcgt accgccaatc acaataaatt ggcccgtgat ggccaaaaga cgcgatttgg
    12361 tcaatgacca gctttcccga atggctgctc gaaaagaacg atctcgtaga atcatttccg
    12421 gtaaagcaaa aatcagtcga atcccaatat agccaaggaa aatataaacg agtaaaaagg
    12481 aactgacgat gatccaacga ttagcaaaaa taaaatccat aatgaaagcg gggattttta
    12541 tttttgacag tagatcagaa ttaaaactta atccgctgat cggtagaatc aataaaaaat
    12601 aagcaaggaa aaacaaaaaa gtaatgggtc tcactttctt cagctgaagt atcgtcaagt
    12661 gtaagagttg cttcaaagag attggttctt tctttttaat aaaaaaaaca ctcatcaaaa
    12721 gaaaagtaaa ttcgaaataa actaacagta aaatcgtcat caaaactacg attaacgaga
    12781 gtagaacccc aggatgttga gaaaaaattg aaggaatatt gtcataagac aaatagtcaa
    12841 ttgcccctcg gtgtaaaata aaacgggtcg tactgctcaa taagggtaaa caaataaata
    12901 aaataaagcc atgcatcagc aagacatcac ggaaataagc ttgtgttcct tttaaaaagt
    12961 cccaagcatt acctaagcta cgtttcaaat aattcatcct atcacctgct cttcacattg
    13021 tagcgcaaat ctaatgaaaa aggaaagggt gcagtgtgtt ttgcagaccc tttcccagat
    13081 ttaa
//
LOCUS       DAZUJR010000080        12993 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.080, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000080 DAZUJR010000000
VERSION     DAZUJR010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12993
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.080"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..608
                     /locus_tag="ACG804_002264"
     CDS             <1..608
                     /locus_tag="ACG804_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833185.1"
                     /translation="ENQLFAGDVLEIVLNDQAGEAAAKGVQNKPSTNDEIGNHNPSDT
                     PVVYHDAPPFAPATKIVVEGGLSFLAPSKLDCGQIKATGLTQEAFGQMDIQEKLWIYD
                     QRETKSPWILTIKLSQPFTTDAGFSMQDVLYFKKAEEYQLVNEEELEIVRGQNSTNVQ
                     TDYSEYLNNGRAFKLVLTKENQIAGNYSAEMTWTLADAPTE"
     gene            628..1656
                     /locus_tag="ACG804_002265"
     CDS             628..1656
                     /locus_tag="ACG804_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HFS4833186.1"
                     /translation="MNRIWNKSHRNNCSLLLILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILIRNSEKESSPNLKLKKTYADQSDGRNVIKANLQNPNAS
                     YMFGLTTSVEIYKKETKEPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKG
                     AWKEKRWNLHTDFEITDDAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFI
                     LKERRKKK"
     gene            1653..2411
                     /locus_tag="ACG804_002266"
     CDS             1653..2411
                     /locus_tag="ACG804_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFS4833187.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPNEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QNGTDSTGTATQVQNFVQVTDKSGIYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGTPSTISGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEGKA"
     gene            complement(2497..3237)
                     /locus_tag="ACG804_002267"
     CDS             complement(2497..3237)
                     /locus_tag="ACG804_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFS4833188.1"
                     /translation="MKKYFIIEDNQFHSEWIIKELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            3298..4551
                     /locus_tag="ACG804_002268"
     CDS             3298..4551
                     /locus_tag="ACG804_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFS4833189.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGFIALMVVTLL
                     FPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGLRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            4846..5100
                     /locus_tag="ACG804_002269"
                     /pseudo
     CDS             4846..5100
                     /locus_tag="ACG804_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308281.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            5222..5548
                     /locus_tag="ACG804_002270"
     CDS             5222..5548
                     /locus_tag="ACG804_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HFS4833190.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLQLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEF"
     gene            5616..6329
                     /locus_tag="ACG804_002271"
     CDS             5616..6329
                     /locus_tag="ACG804_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HFS4833191.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYLVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PIFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEEKEIVTLITCGDMDAVTRLVVQGELESVTP
                     IKDATDDMRSAFNLETKTF"
     gene            6639..7491
                     /gene="licT"
                     /locus_tag="ACG804_002272"
                     /pseudo
     CDS             6639..7491
                     /gene="licT"
                     /locus_tag="ACG804_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
     gene            7612..9477
                     /locus_tag="ACG804_002273"
     CDS             7612..9477
                     /locus_tag="ACG804_002273"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFS4833192.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            9491..10934
                     /locus_tag="ACG804_002274"
                     /pseudo
     CDS             9491..10934
                     /locus_tag="ACG804_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738852.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
     gene            11042..11743
                     /locus_tag="ACG804_002275"
     CDS             11042..11743
                     /locus_tag="ACG804_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFS4833193.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            11869..12381
                     /locus_tag="ACG804_002276"
                     /pseudo
     CDS             11869..12381
                     /locus_tag="ACG804_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014566402.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(12779..12988)
                     /locus_tag="ACG804_002277"
     CDS             complement(12779..12988)
                     /locus_tag="ACG804_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit beta"
                     /protein_id="HFS4833194.1"
                     /translation="MYYFKQQILVSFINEKIILFSCYVSLINDVSLNKKADELNDQNL
                     IIFVHQLLLKIFLLTINSWICKNIT"
BASE COUNT         4370 a         2177 c         2741 g         3705 t
ORIGIN      
        1 cagaaaatca actttttgca ggagatgtat tagaaattgt attaaacgac caagcaggag
       61 aagctgctgc taagggtgtg cagaacaagc caagtaccaa cgatgaaatt gggaatcaca
      121 atccaagtga tacgccagtt gtttatcatg atgccccgcc ttttgcacct gctacgaaga
      181 ttgtagtaga aggtggtctc tcatttcttg ccccttccaa actcgattgt ggtcagatca
      241 aagcaactgg gttgacgcaa gaagcatttg gccaaatgga tatacaggaa aaattatgga
      301 tttatgatca gcgagaaaca aaaagtccat ggatcttaac gataaaatta tctcagcctt
      361 tcacaaccga tgcaggattt tctatgcagg atgtcctata tttcaagaaa gctgaggagt
      421 atcaattagt gaatgaagaa gaactggaaa ttgtcagagg acaaaattca acgaatgtgc
      481 aaacagatta ttcagaatat ttaaataatg gtcgggcgtt taaacttgtc ttaaccaaag
      541 aaaatcagat agctggtaat tactcagcag agatgacatg gacattagca gatgcgccga
      601 cagaataaag atcaaggaga atgattgatg aatcgaatat ggaataaaag tcatcgaaac
      661 aactgctctt tacttctgat ccttctcctt ggattcatcc tttggcagac acctgtccat
      721 gcctccgaat tcaattttgc ggtagatttt gaattaccgg ctaatcagat tgataagaac
      781 aaaacatata taaatgtaag gatggagcct gggaaaacac aggaaatccc ctacacggtc
      841 tttaaccgaa cagataaatc agtaacagtt gagacattga tccactccgc tacgacgaat
      901 tcaaacggtg tgatcgaata tggagaatca aaaagtaaat ttgatgaaac attaagttat
      961 gatatgaaaa acttagcaaa aacagtggga gaaataactg tccctcctca aagtgcggtc
     1021 actgagacac tttcactgaa agctccagaa aaagagctgg ctggtgtggt cgcaggagga
     1081 atcacgtttc aagaaaaaaa agagaacgtt tctaacaaaa gtacagttgg tgtcgtcaat
     1141 cagttttctc aagtgaaagc aatcttgatt cgaaatagcg aaaaagagtc ttccccaaat
     1201 ttgaaattaa aaaaaactta tgcggatcaa agcgatggaa gaaatgtgat taaggcgaat
     1261 cttcaaaatc caaatgcttc ttatatgttc ggcttgacta catcggttga aatctacaaa
     1321 aaagaaacaa aagagcctta tctttcaata aaaaaagaaa aaatagatgt agcacccaat
     1381 acaaattttg atttacttgt cccattagaa ggaaaaaaat tagctccggg acattatcaa
     1441 gcggttgtga agggtgcttg gaaagaaaaa cgctggaatc tccataccga ttttgaaata
     1501 actgatgatg cagcggacca attgaatgaa aaggatattg atttaaaaaa tcagccagaa
     1561 acatttgact ggcgatggct gatacttgtt ggagtcattc ttattggctt atttgctgga
     1621 ttatttattt taaaagaaag aaggaaaaag aaatgaaaaa aacaattgca ttaagtaccg
     1681 ttctagctgg aagtctatta ttatgtacac aaagtgtttt tgctgagaat aagagctcag
     1741 ccactacaga aggaacgatt tctgtaacaa aaccagatgc cgcaaatcct gaagacgttg
     1801 ttccagttcc tcctgttgat ccaaatgatc ccgatacgcc gtttacacct aacgaaccaa
     1861 atcagggaac atccggatta ctgacgattg accaagctcc agatcttgat tttggaacaa
     1921 tcaagttagg tacagcaaaa acagtatatg ctgcattaca aaacggaacg gacagtacag
     1981 ggacagcaac acaagtacag aatttcgtac aagtaacgga taaaagcgga atttatgccg
     2041 gttggaaact atcagtcaaa cgaacagaat ttattggtac aacatctgat acgaataaac
     2101 taactggttc aaaggtgaaa ttcaaaaacg ccgtgattcg aaatagcgca actaatagca
     2161 gtggaacgcc atctactatt tctggtactg gcgctgaagg aattgagatc ccagcagatc
     2221 aggcagtaga tctagtaact gcaggagcaa atgaagggat tggcacatgg atttattcat
     2281 taggagagaa tgtggaacaa gggagacaat cagtggaatt atttgttcct gtatccaatt
     2341 atgccgtaga caactacgtt tcaacattca catggtcgtt aacagatgct cctacagaag
     2401 ggaaagcgta aaatcaaatc aatgacttca gggagtggag ccgattcaag gccaactccc
     2461 tgaaatctgc tatgcttacg tctcagctct tattcatcaa ctcgaagcag ttttttggaa
     2521 gtcatggaaa cgttcctttg tcttttcaaa gatctttcga ccaacgagta aggagtcacc
     2581 attgaaaaat tctaacacat aatgagcaga atcaattttc tgcaattgcg ataagttgat
     2641 acagtaagat tttaatagta aaaagtaagc atacttttcc aactctgtct tcaattgttt
     2701 taaagaagta ttcactaatt tatcttctgt agttgttttg accataactt ggtttttcaa
     2761 acctttgata ctttcaatat ataaaatttc ccgaggatac aggacgagac ttccaccttt
     2821 ttgatcaata aagattttat cgacatttac gatttgctgt tctttccaat tgatctgttc
     2881 tagcacttga cgaatttgtt cagataaatt cctgtctttt ctgatatatc caatcggaag
     2941 gattttccga ttgatgatct ctactgcaaa attcgtataa gcggtgaaaa aaacaatatt
     3001 actatgtgca ttttttttac gtatttgttc ggcgacatca atacctgtga gtgattgctt
     3061 caagtcgata tcgataaaga aaacatcgtg attatcaata gtacccaact ggatcaactg
     3121 attgatttga gagatagaag tgagctgcac gatattctcg atatgatgat tgaccaattc
     3181 tttgatgatc cattcgctgt gaaactggtt atcttctatg ataaaatact ttttcatatg
     3241 caggctccta ttaaaaaaat atgtgtacat tttgaaacaa aacaatggag gaataagatg
     3301 gtcgcaacag tgacacttta tttgaccttt actttgattt tagatttagg tatctattta
     3361 ttcttttcga aacaactgct agtaaaaaac agctttggtt ttatagcttt gatggtggtg
     3421 acacttttat ttcctatccc taaagtgagc tttccttacc tagttggctt attattgatg
     3481 tttctttttt attttactac gaaaaacctg tttatcagct gtttgatcag taatcttttt
     3541 tttgctatca ctggactcag cttttttctg gtttttgatc tgatggatta tttaggaaag
     3601 agacatcttg gaacagcaag tttttttgca ctacttatcg catttatttt ctatctatta
     3661 gtaaaaagta tagacaaaca gacgagattt ctcaacttgc tttttactta tccaactgaa
     3721 cactattttg gaggtatttg tattttatta agctggggcg tgatttactt ggtattggga
     3781 agtgttcact tccgctcatc taattatctg cttctatctc ttttgtcgat agtcatcagt
     3841 tttttttctt tgtttttttc cattatgttg atcagtttcc aagtaaaaga aagacaacat
     3901 caggaatcgc ttcaactgta tcaaataaat gaagaatatt accatcatct agaggaattc
     3961 aaacatgatt ataaaagtct actgttttca ttaaaaatta ctcttcagga aaataaaaaa
     4021 gaaacgttgg aatttttaga aatcttagaa gatcattctg cagctatttt tgaaaaaccg
     4081 caaatacaac agctaacaaa tattgtatcc ccagctgtca ggggtgtctt tttaaaattt
     4141 ctagaaaaag cagaatcgga gaaaatcccg atccaagtag ttattcctgt cgaagtgaaa
     4201 acaatcccga ttgatctggt tgtttttatt cgctgtttat ctatttttat ttctaacgca
     4261 ttcgatcatc gtgtagccga tcagagtccg attacgatca atctgctgga agaaaaagag
     4321 ggattacgtt ttagtatagc gaacaaggca aatccgacga atttgacgct atcggagatg
     4381 gtcaaaagag gaaaaacctc taaaaaaaat ggcgggttag gtctatacag tgcgaaaaaa
     4441 atgttggatg tttacgaaaa tgcagaacta aaaatcgaat tttcaaaaca gaatcactat
     4501 ttttttgtag aaatgtatct ggcatctaga aagagcaaat cagcctactg acttactgtc
     4561 aaaggataag cttgaggaaa gtctacacgg agatagagac aacaacacag catattcaaa
     4621 agaaacagaa gcgtgatgac cgttgtcacc cttctgtttc ttttgctatg tagttaaaca
     4681 aagtagttga cacttccgct acttagtatt agtacgaaag tatacttcat gatactaagt
     4741 agataagaag tgaaaagcgg aacccacgat cgtcaaaatg ctaactgctt tgcttacacc
     4801 agataaaggg aagagcaata tcgcttattt taggcgtgga gaagcaagaa aatccctacg
     4861 atcacacaaa aaatgctgac ccagcagtta agagagttag aacaagatgg cattgtccat
     4921 cgaaaagtct ataaccaagt cccgcctaaa gtagagtact cgctcaccga agaaggaaaa
     4981 tcattaagag agattctagt agcgatgtct gtttggggag aagaacgtat cgaaaaacaa
     5041 aaagcctcag gggaagaagt cacattactg catacacatg gtggctacct aaattactga
     5101 tttctatgac atttatttta aataaaagaa aacaggagtt tttttaaaag catcatctat
     5161 tttttatgta aaaaaatggt atgattaatc aagtaagaaa tgattggaag aaggcaagca
     5221 aatgaatagc atggaaaaag ttaaccagtt tagagatgaa cgtaattggc gacaatttca
     5281 taacgaaaaa gatttggcta tttctatttc tttggaagca tctgaattgt tagaactttt
     5341 tcaatggaaa acgccggaag aagtaaaaga aacacaatta gaacgaatca aagaagaact
     5401 ggcggatgta ttgatctatt catacatgat ggcagacaac cttcagctgg atctagatga
     5461 gatcattgaa gaaaaattga tcaaaaataa tttgaaatat cctgtagaaa aaagcgcagg
     5521 tgtacgaaaa aaatacacag agttttagaa atgtgtcatt cggctgttgg aaagagcaaa
     5581 agaaaaacag taaaatgagt ctggagggag agaaaatgaa aaaaaaagga aaagcaaaaa
     5641 gatggctagt caatatcctc ttgttcctct tgttattagt aggactagct ttgattttca
     5701 atgaacagat caaggattat cttgtcagag agacaggaga taaatatgct atagcgaatg
     5761 taacaaaaga agatctgaaa aagaataacg ataaagatgt cagttttgac tttgatgcgg
     5821 tagaaccaat gacgacagaa ggggtcatga ggtcgcagat gagaggaaca gatctaccag
     5881 tgattgctag tatcgcagtc ccttcagttt caatcaattt accgattttc aaaggcttgg
     5941 ataatacgtc actactttac ggagcaggaa cattatctcc agatcaagaa atgggaaaag
     6001 gaaattatgc cttagcaagc catcgtgcaa cgaaccctga attgttgttt acaccgctgg
     6061 aaaatttaga gatgggtgcc aagatctatt tgacagattt agaaaatgtg tatacataca
     6121 aaacattttt taaagaaaaa gttgctccta cagataccca attactgaat gaagtcgagg
     6181 aaaaagaaat tgtcacacta attacttgtg gcgacatgga cgccgtcacg cgactagttg
     6241 tacaaggaga actggaaagt gttacaccga taaaagatgc gacagatgat atgagatctg
     6301 ctttcaatct agagacaaaa acattttagg atactgggac ataagtcgtt acagattaaa
     6361 aacagccaaa ggatatgaat cgataaggaa aaaccaattt gctgaaaaaa agaggaacgc
     6421 aaagaggtgc atctctgatt tggttgtttt ctagatagac ttgtgttcca gtttttttat
     6481 tttttatatg aaaaggcttg cataaataaa aattcgatgg tatgatgatt ttgaataaga
     6541 aatggattgt tactgtacgg caggcaaaac cagaattcag ctaagaaaca gtaggcgaat
     6601 tctaggtttt tttatttttc ttgagagggc gaagcaaaat gaaaattgat aaaattttga
     6661 ataacaatgt cgtcatttcg aaaaatggat tcggggaaga agtcgtttgt atgggaaaag
     6721 gactagcttt tcaaaaaaaa gattggggac gagatttcgc cagaagcggt ccaaaaagaa
     6781 tttattttaa gagattcttt tgctaaaaac caattccagc agctgatggc tgatattccg
     6841 gcagaggaga tcgaatgggt caaacaagta gtcgaactgg ctgaagataa actaaaagtt
     6901 gaattttcgc ctaatattta tctgacattg accgatcatc ttcattatgc gatcacacga
     6961 gcaaaagaaa atatccaact gcctaatcca ttattatttg aaacaaaaaa attttatccg
     7021 aaagaatatc aagcagcgaa agaggctctt ttgttcgtga aacaaaagac gggtgtggaa
     7081 ctttctgagg atgaagccgg ttttattgcc tttcattttg tgaatagcca acaaggaaac
     7141 gaagacatgc aagtgacgat gaccgctacc acaatggtaa gagatatact gagtatcatc
     7201 agtaaattct tcggcatcgt gttcgatgaa gaatctttga attatcagcg tatcattact
     7261 catctgcagt tttttgccca gcgttatctc aaaggggaag gatctgacga gcaagatgaa
     7321 tttctctacg cattagttca aggaaagtat ccaaaagcgt ttcattgtgt cgaacggatc
     7381 aatgagtatc ttcgacaaac gcaaaaacag gaaatgggga tcgcagagca gatttattta
     7441 acgattcata ttcaaagagt agtaagtgag aaaaaaagca tccaatcata aggattgtta
     7501 ctgtatggca ggcaaaacct ggattgaaaa aataggttca cgaatgtttg tgactgtttt
     7561 tttcaatctg ggtttttatt ttttaaataa aaaagaaaga aggaaaaaac aatggataat
     7621 caagcagttg gtcgtcgtgt atgggaagcg gtaggaggac aaaagaatgt caaaagttta
     7681 gtacattgtg ctacgcggtt gcgattcaga ttaaaagatg aatctttagc agatacgcaa
     7741 aagttaaaag aagacccgga cgtgatccaa gtcgtacaaa gtggcggtca gtatcaagta
     7801 gtgattggca gtaatgtagc agatgtttat caatcgatcg tggatgagga aggtcttgca
     7861 gtttcggagg atggaaaaga agagtccaaa aatattttga atcgtctgat cgatattatc
     7921 tctagtatat ttacaccttt tctaggggcg atggcagccg ccggggtatt gaaaggattc
     7981 ttatcattgg caacggtgat gggctggctg acagctgata gcggtactta tcaaatattg
     8041 tttgctgcag cagatggtgt ctttaccttc ttacctgtca tgcttgcttt tacagcagct
     8101 aaaaagttca aagccaacca gtttttagca gtagcaattg ctatggcact tgtgtatcca
     8161 gctatcacag cagttgctgg tgcgggagaa gctatcagtt tctttgggat cccagtgatt
     8221 ctttcaccat ctggttatac ttcttctgtc ataccaatca ttctagccgt atgggttcaa
     8281 agtaaattag agccattcgt aaaaaaagtg attccgcaat ttctgcaaat gattttagtt
     8341 ccgcttgtcg ttttagtagt gatggttcca ttaacatttc ttgctttagg accaatcggg
     8401 acggttgccg gtaatgcttt aggcggtctc ttcaactcga tttatggatt tagtccaatc
     8461 gtagcaggtc taatcatggg aagtttatgg caagtattcg tgatgttcgg catgcattgg
     8521 ggattcgtac cgatcatgtt tttgaatatc gaacaatatg ggtttgatgt attgatgcca
     8581 atgcttcttc cagccatctt ggcacaaggt ggggctgctt tagctgtagc attgcgaaca
     8641 aaagatacga aacttcgagc attagggatt tcttctacag tgacttcgtt atttggaatc
     8701 actgaaccaa ctgtgtatgg tgtgacatta cctttgaaga aaccattcat tgccgcttgt
     8761 atttctggag gtattggtgg agctattatc ggattttccg gagtaaaagc tttctccagc
     8821 agtttggtca gcttattgac gattccgact ttcattaata cggtggatgg tgtagagtca
     8881 aatgtgacag tagcagtaat agctacagga attgcttttg ttcttgcatt cgtaggtaca
     8941 ttgattttag gatttgacga acaaacacaa gacaatcaat tagaaaacaa acatgcgaat
     9001 gcaggagaac cgattacttc agcacggcat accttaaaaa gtcctttaac gggtaaagta
     9061 ctgccattga gtgaagtacc agaccaagtt ttttcttctg gcgtgatggg aaaaggtatc
     9121 gctattgatc cagaagtagg agaactagtt gcacctgcag acggagagat cacgactatt
     9181 tttccaactg gacatgctgt agggatcaca acgactgacg gagcggagat tttgattcat
     9241 atcgggatgg atacagtaga attaaatggg aatggctttg agatcttagt caaacaaggg
     9301 gatctcgtca aagcaggaga tttattgatt cgttttgaca tcgaagcaat tagagcagct
     9361 ggctatagcg taatcactcc agttgtcatt acgaatactg atgcatttgc cgatatactt
     9421 gaattagacc aaaaagagat tattgcaaac gaagatgttc tggcaattgt aaaataagga
     9481 ggaaatcagg atgcaatcac gtttttcaga aaaattttta tggggtggag caactgctgc
     9541 caaatcaatt agaaggggct tatgatcgag acggaaaagg actatccgtt gcagatgcta
     9601 tgcctggagg taagcagcgc tttgcgatta tcggcagtga agaatttgac tggacgattg
     9661 atcaagaaaa atatatttac ccgaatcatc gaggaatcga tcattacgat cgtttcaaag
     9721 aagatcttgc cttgtttgcg gaaatgggat tcaaatgtta tcgtttttcg attgcctgga
     9781 cacgaatttt tccaaatgga gacgaaggta ctcctaacga agcgggatta gaattttatg
     9841 atcagctgat tgatgagtgc ttaaaatatg atattgaacc tgtgatcacg atttctcatt
     9901 acgaaatgcc tcttcatttg gcaaaagaat acggtggctg gaaaaatcga aaactgatcg
     9961 acttctatga acgatttgct cagacagtat tagagagata cagcagtaaa gtcaaatatt
    10021 ggatgacttt caatgaaatc aattcggcct ttcactttcc agctttaagt caaggattag
    10081 taaaaagcaa tggagcagga gagtaccaaa atattttcca agcatggcat aatcaattcg
    10141 ttgcaagtag caaagccgta aaaatcggcc acgaattgcg ttcggatatc caaatcggct
    10201 gcatgattat ctatgcaaca acttacagca tcgatgccaa tccagtcaat caggcagcaa
    10261 caatgatcca aaaccaagaa ttcaattttt tctgcacgga tgtccaagta cgtggagaat
    10321 accctgcata cacagcgcgt acccataaaa aatatggagt cgatccggaa aaattagagc
    10381 aaacggaaaa agacttccag ttgctaaaag aatatccagt ggactacatc ggatttagtt
    10441 attatatgtc tacggcaatc aatgagactg atccacaagc agcaacttca gaagggaact
    10501 tgctgggagg agtaaaaaat ccgtttcttg aggcaagtga atggggctgg cagatcgatc
    10561 cagaagggct gagaatcgca ttgaatgaat tatacaatcg ttaccagaaa ccattattca
    10621 ttgttgaaaa cggtcttgga gccattgatc atatggaaga ggatggcacg attattgatg
    10681 attatcggat cgattattta cgtcgtcata tcgaagcgat ggctaatgca gtagcagacg
    10741 gtgtagattt gatgggctat acgccttggg gatgtatcga tcttgtcagt gcatcaacag
    10801 gagaaatgag taaacgttac ggctttatct atgtggatct agacgatgaa ggaaatggga
    10861 cactgaatcg atcaaagaaa aaatcttttg attggtataa agaagtaatt gcctcaaatg
    10921 gcgtaaactt gtaattaaag cagctgaatg aaaaagaaca cacttctcac atgtgatttg
    10981 tgttcttttt ttatttttta tgtgctattc ttttagtaat agtaaagcaa agggtgacgt
    11041 tatgaaaagg acacgtgtac tatacttgga agtcgcagat aaaattaaag aagatatttt
    11101 ctcaggaaaa tatccagtcg gttcgatgtt gccgacagaa agtgaattag aagaactgtt
    11161 tcaagtcagc aaaatcactg tccgaaaggc aatcgaactg ctggcatcag atgaatatgt
    11221 cgcaaagaaa agtggtcgtg ggacgacggt tctaagcaat cgtccttaca atcgattatc
    11281 caaagcggca agctttacgc aaatcttgga gaactcccga tatgaagtcc ggaaagaaac
    11341 gctggatttg caattggtcc atataaagaa ggaagatcct ttgttttcct ttttcggtga
    11401 gcaagctgtt tgttttaagc gcttatatta tttgaacaat cagccttata tttattttgt
    11461 tcattatctt ccacaagaaa tgatgcaatt cagcagagaa gaatttggca aagaatcttt
    11521 gtatcgtttg ctgacgaaaa aaggatatac tattgactca ttttctgatg atttctcggc
    11581 agtattttta acagaagaag aacaaggaat tctgaaaaca gacgcacaga tcggcatcaa
    11641 acggatacgg aaatcgtcta cgcaaattgg ggaaatgatt gaatattcgg aggcggtcta
    11701 ccatacggag ctgcatcctt accatattga ttatgaaaca taaataaaaa aagaggttgt
    11761 gaaaaagctg ccctgcatca agtaataaga acagccaaac aaaaatagct tctcatattt
    11821 ttcgtttggt taggcttatt accgcagata cacggctgtt tctggattac catttattct
    11881 ggataagggg gtgtggcacg attttcagaa ggaatctatg aaccaatcac tgtattgatt
    11941 ttagcttcga tggtaacccc attcggcttg acgatcgctt atttcttagg gaaaatcatt
    12001 cgtaaaaata tactcaatcg tcaagaaatc gatacattga agaccgcttt tcctatgggg
    12061 atctgtcaga tcacagaggg atgtttccct atcgtattga acgacttggc acgcaatgtc
    12121 atagcaacgg gagtcggtgg gacagtaggt ggcggattaa gcatgttttg gggcgcagat
    12181 agccgtattc cggcatcggg aatgtttgca gtcgctacga tgaccagacc atgggcattc
    12241 attggtgcat tgttagctgg ttcttttgtc acaggaataa ccattttatt attgaaaaaa
    12301 ccagtagatc cgaatgcaga aatcatccaa gaagaaaaag aggaagaaga catatcttgg
    12361 gatgatttga caattagtta ggagaggcag aatggattac aagaaaaaag tacaatagat
    12421 gtaccttgag acaggaatgg tatgaaagaa tcagagttag aaagaatcga atatacagat
    12481 tttggtttag gagcgatcga aactgtccag agcatcggca ccctccttga aatgacgatg
    12541 aaggaaaaat gagaaccttt cgttgtcgaa agggtctggt ataccttatg tcgaaggaaa
    12601 ggaaacaaaa aaactttcct gtactattcc aaaaaggaaa gaaagttatt atacagtaaa
    12661 aaaagaaatt attcttcatg ctagagatca gtacacgttc gagcccaata tcaaacacta
    12721 gttccaggca ggcgcaacag gtgcggttat cactgaattt tcttccagca gtgacgattc
    12781 aagtgatatt tttacaaatc cagctattta tcgttaacaa aaagattttt aggagaagct
    12841 gatgaacaaa aatgatcaaa ttttgatcgt ttagttcgtc ggctttttta tttagagaaa
    12901 catcatttat cagtgaaaca taacacgaga acaaaatgat tttttcgtta ataaaagaaa
    12961 caagtatttg ttgtttaaaa taatacacgt tat
//
LOCUS       DAZUJR010000081        12868 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.081, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000081 DAZUJR010000000
VERSION     DAZUJR010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12868
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.081"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(342..704)
                     /locus_tag="ACG804_002278"
     CDS             complement(342..704)
                     /locus_tag="ACG804_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833195.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(778..1158)
                     /locus_tag="ACG804_002279"
     CDS             complement(778..1158)
                     /locus_tag="ACG804_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvfD/Ygs/GSP13 family RNA-binding
                     post-transcriptional regulator"
                     /protein_id="HFS4833196.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1240..2415
                     /locus_tag="ACG804_002280"
     CDS             1240..2415
                     /locus_tag="ACG804_002280"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HFS4833197.1"
                     /translation="MIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADMDFLSPG
                     GVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVLTSLAAA
                     VQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDMEKKIEEN
                     NVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHTFTSMLT
                     IDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEINTFGLI
                     GTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLDFTAYIS
                     DDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYALETID"
     gene            complement(2492..3076)
                     /locus_tag="ACG804_002281"
     CDS             complement(2492..3076)
                     /locus_tag="ACG804_002281"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFS4833198.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            3277..4275
                     /locus_tag="ACG804_002282"
     CDS             3277..4275
                     /locus_tag="ACG804_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFS4833199.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            4387..4896
                     /locus_tag="ACG804_002283"
     CDS             4387..4896
                     /locus_tag="ACG804_002283"
                     /EC_number="3.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HFS4833200.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(4926..5585)
                     /locus_tag="ACG804_002284"
     CDS             complement(4926..5585)
                     /locus_tag="ACG804_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HFS4833201.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(5587..6351)
                     /locus_tag="ACG804_002285"
     CDS             complement(5587..6351)
                     /locus_tag="ACG804_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HFS4833202.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(6359..7036)
                     /locus_tag="ACG804_002286"
     CDS             complement(6359..7036)
                     /locus_tag="ACG804_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HFS4833203.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(7073..8458)
                     /locus_tag="ACG804_002287"
     CDS             complement(7073..8458)
                     /locus_tag="ACG804_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HFS4833204.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(8668..8752)
                     /gene="ffs"
                     /locus_tag="ACG804_002288"
     ncRNA           complement(8668..8752)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACG804_002288"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(8775..9290)
                     /gene="tadA"
                     /locus_tag="ACG804_002289"
     CDS             complement(8775..9290)
                     /gene="tadA"
                     /locus_tag="ACG804_002289"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HFS4833205.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            9397..10254
                     /locus_tag="ACG804_002290"
     CDS             9397..10254
                     /locus_tag="ACG804_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4833206.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(10335..10670)
                     /locus_tag="ACG804_002291"
     CDS             complement(10335..10670)
                     /locus_tag="ACG804_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833207.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(10737..12107)
                     /locus_tag="ACG804_002292"
     CDS             complement(10737..12107)
                     /locus_tag="ACG804_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HFS4833208.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(12185..12721)
                     /locus_tag="ACG804_002293"
     CDS             complement(12185..12721)
                     /locus_tag="ACG804_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFS4833209.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
BASE COUNT         3845 a         2603 c         2129 g         4291 t
ORIGIN      
        1 tcttttttaa cgactcagtt atcttatcat gtcgttagta acatgtcaat aactattttt
       61 taaatttttt agaaatgtga tataacatcc acttcagaat caacgctgtt aaatttatca
      121 tgtatttctt ccttggtcaa ctataaatta agcattactt tgtgaaatga tttttcgatc
      181 aattattatt attcgttata caaccgtttt caacatattt tgaaaataaa atgcactaaa
      241 aaactatctt tagcagaaca tttcattgta ttttttggac caaacaataa aaaaagaagt
      301 ttgaaaaaaa ttcaaacttc tttgttcgct taatctgtat tttagaagaa aggcactccc
      361 tctacttcgt aagttccaag aacagagcgc atttgacctg gttcttccca aatatatcct
      421 tcgcctaatt cttctctttg attcttttgt tcagtttcaa agacaaacaa cggaacattt
      481 tcctctttaa tatgtgtatt tgtcaattcc atcaaactaa tcttgctaac atcgatatga
      541 actatttctt ttaagaaatt aagtatattc gctaaaccag tctttccttc agaaagttcc
      601 gctaacgcaa attccaactt gtcatcaatt gaatggacca aaaatttttt agtaccatcc
      661 tccaaatgca acataattgt accagcaact cttttgcttg ccaaaatttc cacctcgatc
      721 aacttgttct atggcttaca taaaaattct agcacatttt cagaaaaaat acacttttta
      781 tttcttattt tctttccgtt ctagttcaga taatgcttct tctatccaaa taggtaactg
      841 ctccgcaata gtggtaaatc cgatcttacg atttttattc gtgaaatacc tttttctgcg
      901 atatggaaca gctggatttg ttttttctaa cgttcttaaa gataaactga tttttttgga
      961 atattcatca atgtcgatga tctgaactgt tactggctgt ccgactttta acaatgaatg
     1021 gatatttttc gtataaccgg attgtacttc tgaaacatga ataagtcctt gcgtctcgtt
     1081 atcaagagaa acgaatgcgc cataaggctg tatccctgtc acttttcctt caattatttg
     1141 tccaatttta taagtcatct acttccctct cttcgcattt atcattatac tgtaaatagc
     1201 tcaaaaaaag aagcgacgaa aatgactgga ggtcttaaga tgatcgaatt tgataaacag
     1261 atttcaagaa aagatacaga aagtgtaaaa tgggacgcaa ttgctgagac atatcaaatg
     1321 gatgacttac ttcctttgtg ggtagcagat atggacttct tgtctcccgg tggggtagct
     1381 aaagcgttta gtgaatacat caaacatgga atctttggtt atgccactct gtctgataaa
     1441 ctatatcagg ctatcattca ttgggaacgc caacaccatg ctgtggagtt gacgaaagaa
     1501 aatatcgttt ttacaagtgg tgtgttaacc agtttagctg cagcagtaca aacttttaca
     1561 aaaccaggcg attctatttt gattcatgac ccagtttatc ctccattttc ctctattata
     1621 gaaacaaatc aacgtcacat cgttcgaagc tctttgctag aaaaaaataa tcatttcatc
     1681 atggacttgt ctgacatgga gaaaaaaatc gaagaaaaca atgtaaaagc aatgatttta
     1741 tgcaatcctc acaatcctgg agggcgtgtt tggagcaaag aagaattgaa acagttaagc
     1801 gaattgtgtt taaaacatca agtgattctg tttagtgacg agatccatca agatttaact
     1861 ttattcgatc atacatttac ttccatgcta acgattgatc ctaatttaga tgatctacta
     1921 gttgctttta cttccgcaac caagactttc aatctagctg caatcaaaaa ttcaatggta
     1981 tttatcaaaa atccagagat gaaagctgat tttgaaaaac atttagtgat gaaccaacag
     2041 cacgaaatca acacttttgg actgattgga acccaagcgg cttatgagac gggtggagaa
     2101 tggttaagcc aactgattcc ttatctagaa aaaaatgttc aaacagttaa tcagtttttt
     2161 gaacagtatc ttccgaaagt gagaataatg aaccctgaag gaacttactt aatgtggtta
     2221 gattttaccg cctatatttc agacgaccaa gaattggaga acactcttgt tcggaaagga
     2281 aaagtcgtat taaatcctgg catcacgttt ggtccttccg gtcatgggca tatgcgcttg
     2341 aatattgctt gtccagaaga aactttactg gaaggactta atcgaatcaa gtatgcttta
     2401 gagacaatcg attaaatcat ttattcaaaa taaaaggacg agaccttact aggtttcgtc
     2461 ctttttcata attactccgt accataccaa actattctga aatttcaatt gtttcaatca
     2521 ctacatcatg tacaggtcgg tcttgtggac cacgttgtac atttgcgatt tcatctactg
     2581 tgtccatccc ttctagtaca tgtccaaaga ctgtatgtcg gaaatctagc caaggagttc
     2641 cgccaccttt atacgcttca atgatttctg atgggaatcc agcaccttct agttgtccaa
     2701 gcatattagc tggcacattt gtgttattta caataaagaa ttggcttccg tttgtgtttg
     2761 gacctgaatt tgccatagat aaagctccgc gaaggttgaa cagttcacga ctgaattcat
     2821 cttcaaaact ttcgccataa atactttcgc cacccattcc tgttccagtt ggatcgccgc
     2881 cttggatcat gaaatcagga ataacgcggt gaaaaatcac gccatcataa taaccttttt
     2941 tggaaagttc aatgaaattt tgaaccgtct tcggtgctag ttcagggaat aattgaacag
     3001 taatgtcacc acggtttgtt ttgataacag cttttggtcc tttttcactt tttaaatcta
     3061 gttgtgggaa tgccatattg tttcctccta atatttgcat acttcataat aataataaca
     3121 taatacctaa cctctcgtaa aaatactaga tttgttttct tttatttttc atcactagat
     3181 acattctata acttaccgtt tcgatttcga attcaaacat ttttgagaag cattctcaat
     3241 taaattctga tatagtgtga aaagggagga atttttatgg aaatctatga cattacaatc
     3301 atcggtgcag gtcctgtagg gatgtttgcc gctttttacg caggaatgcg ccaagctaaa
     3361 acaaaaatca ttgacagtct acctcaactt ggtggtcaat tagcaacttt gtatcccgaa
     3421 aaatatattt acgatattcc tgggtatcca gcaataaaag caagtgaatt aatcgatcaa
     3481 ttagaaaaac aattaactac ttttaaccat acattccatt taaaagaaga agttctctcg
     3541 cttactcgtg aagacgaagt tatcgagatt actacaaata aaggcatcca ttattccaaa
     3601 gcagtcattt tagctttagg aaatggttca ttccagccaa gaaaattgaa tttagataat
     3661 gctgaatcat ttgaaaacca cggattggat tatttcgtga atgatttgat gaagtatgct
     3721 ggaaaaaaag tcgctattgc tggaggtggt gattctgcta tcgattggac gttgatgtta
     3781 gagcctattg caagcgaagt ttacttgatt catcgtcgcc cggaatttcg tgcgcacgaa
     3841 catagtgtat cacgcttgaa atcttcatct gtcaacttgc ttactcccta tctcatcgat
     3901 ggattatcag gcaataatgg ggaactgaca gatatccggt taaaaaaagt gaaaagtgac
     3961 gagacgattg atttgatgat tgattctctg atcgtcaatt atggattctc ttctaattta
     4021 gaacatcttt cttcttgggg acttgatagt accagaaatg ccattactgt aaaatcagat
     4081 atgtctactt ctattccagg cgtttatgca gctggtgaca tctgtaccta tgaaggaaaa
     4141 gtgaaactga ttgctactgg gctcggtgaa gcacctactg cagtgaacaa cgctttacac
     4201 tatattaatc caaaggaacg aactcagcct ggtcacagca caagcttata cgataaaaat
     4261 cttcgtccta gttgattttt tatatctctt tgcatttcaa gttaaacccg aaagcagttt
     4321 cttgcatttt tttcatgttc cgttaacatg aaatagagaa agaaaaaata aagggggagc
     4381 aataatatgg tcgtcaaaac tgagacttta gaagaaaagg caagagaact attgaaggaa
     4441 cgtggcgtaa ctgtagaaga tatcgcacaa cttgtcatgt ttttacaaaa agactatatt
     4501 tctgatttga ctttggcgga ttgtactgaa agtgtcaaca gcgtgctaac aaagcgtgaa
     4561 gtacataacg ccattatcac tggaatccaa ttagatatat tagcagaaaa gaaaaaattg
     4621 atgagtccgt tgcaacatat tatcgaagat gacgaaggcc tttacggtat cgatgagatc
     4681 ctagccttgt caatcgtgaa tgtttacggt acgatcggct ttacgaatta tggttatatc
     4741 gacaaggtga aacctggtat tttaaaagaa ctaaacagcc acgatggcgt tcatgtccat
     4801 accttcttag atgatatcgt cggagcgatc gccgctgctg ctgccagtcg attagcacac
     4861 aaagaaccag aaaaaagaag tcgccttact caataattca acaaaaaaag aaagaaaacg
     4921 tctatttaga cgagttcttt cttttttgtt tgtttcaagc tattttttcc taagaaaaga
     4981 aaaacagcaa aaaataattc taataataca aaaaataaga taaagctatg catgaaaaat
     5041 tcttctggaa gtacattgat gattggatca gtaacgggat cgaataacca gtcatcgttg
     5101 ttgaaaaacg tttcatgaaa aaggataaaa aagcgatcaa atcctatcat catgaaaaaa
     5161 ccgaaaacaa ctggcagtaa catgccgatt tgaaacggac gaatcaaccg ccaaagccga
     5221 tcattctttt gcaaatattt gataaacaaa atactcggga tcaaagtgat gaaaaacaca
     5281 gcataatcca ctaaaaacaa aattttcact tcataaaagt gatgggctcc gctagcagaa
     5341 actgggaaat ctggcaagct gaggatggtt ttgaagggat tattgagata attcattagg
     5401 tgatcaaaat ttttcagtaa cgtctcttga tctaaagaag tataatccaa aatttgcaaa
     5461 tgtccgatat caaatacgta tagtggtcga aagttgatcg tcacaccaac tgccagactg
     5521 atcagtgtca gaaataggct gaacaatcca gcatattcca tccactgcca tctcgaattt
     5581 ttcatattag aagctccatt catccagtga ttgtttcaca taggtagctg ggataggcaa
     5641 cccaggtaca tcttcttctt ttgtaaaacc tgataaaacg agcaaagtat ctatattatt
     5701 gcgtatccca gcttggatat ctgtttcata gttatctcca accatgatta cttcttcttt
     5761 ttgcagccct aatacttcaa cggctttatc cataatgatg gcttctggtt ttccgatgta
     5821 gatcggcggc gtttgggttg ctgtctctac aaaagagatg actgaccctg ctccaggaag
     5881 aaggccgcgt tcagtaggta tattcttatc tgggttcgtt ccaatgaaag tagcaccttt
     5941 ttgaatagca agtgttgctt taactacttt ttcataggtc agataattat ctaagcctac
     6001 cactacatag tcaggagcct cttcttccca tgtaaatccg gcagctaaaa tcaagtcaat
     6061 caatcctgct tctccgataa catagacttt tttccctttt ccatctgctt tcataaaatc
     6121 gattgttgcc aaagtagctg tgtagactgt ctctggagct acatgaatgt caaactcatc
     6181 tgctagacga ttagctactg tttctggtga cttagtcgtg ttattggtaa caaacaagaa
     6241 aggtaatttt cttttttgca attcttccac aaatcgttta ccggccggta tgggttgtgt
     6301 cccacgataa atcgttccgt ctaaatcaat taaatatcct ttatagtcca ttcatccact
     6361 actcttccct ttttctgatc gtaaatgctg tttttgtttt ttctacttgt ttaggttgtt
     6421 cttgtttttt tactttttca gaggtttttg ctgactctgt ttttcgattt ttaataaccg
     6481 gttttttgcg attagatgcg actggtcctt ttttctcatc gatatacgca cgattatggt
     6541 tttttttctt ttttcggcgc tgagttgtct tttctttttt accgccgatt ctctcgatga
     6601 caaaatacgc acaaccaaaa ttgcaatatt cgtaaagata gtcttccaag gaatcgattc
     6661 gctgatctgg atgcgcccgt cgattatccg cttggaaaaa tccttttagg cgtagttgtt
     6721 cataacccca atctcctacg atataatcat atcgggctag tacatcactg taacgttctc
     6781 caagcttttc tgcattaaat ccttcacgat aatcggacac aagccgataa tgtctttcac
     6841 ctatcaaaaa attactgtca tctaacagtg tcactagctc gcctttgact ttttctgctt
     6901 taggctcctc aacgatttct tccaaagcag ctgtcagttc ttcggtgact gttgtttcct
     6961 gttcagctga tgattttttc ttagcaattt ctgttttatg ctcaacgttc tgctgttcat
     7021 tttgttttgc agacatgcgt tcaccaccta tcttttttat tataccttgt ttttatttga
     7081 ttgggtagtg agctttcaag taatctccta ccacacttcg gataaattca gggaacaaaa
     7141 attcattttt tccagcaatc tcaatcgttg gaaaaaatgg aacaaacatc aaatgatcta
     7201 cggtagtaaa agtataattt ttattcagat cgattggctt gttcttccaa aagacttgat
     7261 ggttaataga atcatatgtg attccattat agaccatctg cccaaaaatc ttaccgcgaa
     7321 atcccattcc cttcatagga tagttacgta aaaagttacg atttttttct atttctaaaa
     7381 ctaagcggat cagatcattt ccacccaatg tgacatttaa caagtgcatc ggatgcggca
     7441 acgcagtgtg aagctgatcc tgattgaccc gcccttttgg aatttcagtt aaaaacagac
     7501 cactgtttaa tattgctgct tccgtctttc ctcgttcttt caccgcctca aaggctactt
     7561 ggataaacga atgctcattg aagatatcta gactcagaga aaatggcaaa tctgctactt
     7621 ctttttcttt taataattca tgcccacgtt ctagataact atttatttct tgttcatctt
     7681 ctgtaaaagc tgtcattgtt tcggtaggga tggctttggc tgaatgctta aggatttttt
     7741 tctcttcatc gatggttaaa tggacttcac cgacatactg cccgtacttt ccagcggctg
     7801 ctatttggac atcattgatt acgtgacctt ctctgaataa atgatgggtg tgcgatccta
     7861 aaataacatc aattgctggt atttcttttg caatttggaa atcatcctga atcccgagat
     7921 gactcatcaa aactaaaaca tccacttgtg aacgtaaatc ttcgactaat tctggcaaaa
     7981 tatcataagg attccgtatg tcccagccat tcggattata agtaagcgga aatggagcag
     8041 taaatgcaat tagtccgatt ttcgtctggt gtttcgttgt aatgatttta tatggtttcg
     8101 tccatgccgg tggctggagc gtatttttat cgaataagtt atccaggatg atatcaaact
     8161 cagcatgatc gtataaatga ttcaactctt ctttggaatt tcctacgcct tcattgtttc
     8221 ctatcgtcgc tgcatcataa ccaacttcat tcatcagcaa gatattttcc tgtccattcg
     8281 ttgcttctga caatggatgc caacgatcca caaaatcacc tagatctact gcaatcgttg
     8341 tcgttttttc tttcttttcg ttttctcgtt tacgttgatc caaaaacctt ctgatccttg
     8401 gccaattttc taaatgagaa tgcagatcat tcgtatgtaa aatcactatt ttttccatgt
     8461 accctctcgc ctctctttat ctttatcata ccataggcag ctttttcttc cattgaaaca
     8521 agctctattt cagagttttt cctgccttga agcaaattgt ataagtacaa tattcgataa
     8581 atcagtctgg ctaaaaaatc aggaacattc atttttacag tactataaaa ataaaaaaaa
     8641 cagacccgaa agtctgttgt cgtttcatta taatcagaca catggcggaa cctgcttagt
     8701 gctgcttcct tccagacctg acacgcttca caagcccacc attgtcctag cctttcggca
     8761 aagaatagta taccttattt ttcattcgtt gaccagtctt tttttaattt cttttttcgc
     8821 tggcggagct ttcggaaaaa gtcagtcaaa atcatcccac attcgtcttc taaaatgcca
     8881 ccttctacat atgcttggtg gttaaaccgc tcgtcctcca aaagattcat caaggtaccg
     8941 gctgttccgc cttttggatc atacgcgccg aaataaactt ctgctacacg agacaaaatc
     9001 atcgcgccgc tgcacatagg acaaggctct aaggtaacaa aaagtgcagc atcttccaag
     9061 cgccagcttc ccactttttc acaggcttcc ttgattgcaa gcatttctgc atgtgtagta
     9121 gcatcttgcg tggtttctct aaggttatat cctcttccaa tcacttttcc atccaataca
     9181 accactgctc caatcggaac ttcatgaagc atttctgctt tctttgcttc tgccaatgca
     9241 aggcgcatcc atttttcttt ttctactgca tcaagatttg tatttaccaa ttacccttcc
     9301 ctgcctttgt tttttcttgt tttactttag catatgataa aaaggctgta actaactttt
     9361 ttttctatgg taaaataaat acaagaggtg aacaagatga aaatggataa attacttgct
     9421 ctttacccac aagcacagaa aaaaaactct ccagcatcag aagcggatat cctttctttt
     9481 gcaattgatg atgcttttat ctggatcaaa caagattcat tatctcaaca agaaaccagc
     9541 cttttgaaag cgttattccc tgtaatcaac gatcaaaaaa aacacccatg gtatcactat
     9601 ctttttaaag atgcttcttg tgttcaagaa aaaagctttc gtttgatcca gcttcacgtc
     9661 gaatcaaaag gagaattctt aaaaaaagaa tggcaagata ctattttgga attatttcgc
     9721 tattctgctg atttcttttt ttatacagac acagatgcgc tcttagtcga acaaataaac
     9781 cgtgattatc ttgatgctac tgaaatcaac ggtatttttc tatctttaga tgctgatttt
     9841 gatacgacaa cgtctgtatt cgttggttct ttccattcac ctggcaccga cctcgtccct
     9901 ttgtttgctg aagaaagaaa aattttttta acagagcaaa acaatcttta tactcacagc
     9961 cgtacttttt ctatgcaaga tgtggcttta cattactata caaaagatac tgtaaaagat
    10021 agtaagttga tcaaaagtta catagaactg atcaaacaaa atgaaatgga agtgatcatt
    10081 caagaattat ggaatgaatt aggcaatgtc agctctgctg caaaaacact gtttcttcat
    10141 cgtaatactc taaaatatcg aatcgaaaaa tttcaagaac agtctggttt caatctaaaa
    10201 aaagccaacg atttactgtt ttgctatctt ttattgcttc atgaacataa ttaaagatag
    10261 attaaagggg ttgtgacaat aattttgtca caacccctta tttcgaatga atagtgttca
    10321 aaagctagtt tctcttacat cattttttca acaaaatgca ttagccggtc ttttacatct
    10381 tcggttgaat ctttgattga atcaccataa acagagattt tcttttttcc tgatttgatt
    10441 tttgctaaca ttcccatcaa agaatccaag tcactatctg aaagaccatc tacgatttct
    10501 agtaattttt catttccatc aaatttgtca tagacgaatt tttttacttt cgtccgagta
    10561 gtcatatgat ggatcttttc cattactttt cccgatacaa cgactgctgt cgctacactg
    10621 gcagcggctg ctacgcttaa tccgattgtt acttttgttg atgttttcat aagtatcagc
    10681 tcctttttat ctatctccat catagcatag acaaaaaaat aaacgaacta atccactcag
    10741 tgaaatctca atcctttagg gaaaaagttc tttactgttc cttttacttg tttcccaaat
    10801 ccgacaggta tcttatctaa tactagcaaa acccatcctt gattcccatc acgttgaaat
    10861 gtttctcctg ctgtgtaaga ttgccattcc ttttgagtga tcggcaagca aggtatattc
    10921 tctatctttt ttgtagcaag cgctaatgca tagctaggtt caaatcgatt ctttttgaaa
    10981 tctcctaaat gcaaacctgt acgtacgact tttaaaccat cgagagaagg ggctaactca
    11041 ggaacttccc aaagatggtc gttgaacact aaaagtcttc cagtagcttc ataatgaaaa
    11101 tcatttgaaa actccgtcca gagtttttcc tgctcttttg tcatttgcac tttacttttt
    11161 tttcgtgtct tcttttcttt atgcatctga ttttgtccat gaaaagtcag ctttgcaaca
    11221 aaatgtcctt caccctgatc tttatgaggc catatacgta ttgttttttc caaaccagct
    11281 acgcttcccc attcagaacg tcctgaacta acggattgag tcaaaggaat ctcctcaatc
    11341 gttactggat aattttctac aagccagcta atgatctctt cattttcttc tggtgcaaac
    11401 gtacaagtcg aataaatcag ttgtccttta ttttttagca tttttattgc tgaagacaaa
    11461 atctcttgct gacgtttttg acagtatagc ggagattctt ctgtccactc ttttattgca
    11521 tttggatctt ttcggaacat tccttctcct gaacaaggag catcaaccac gatccgatca
    11581 aaaaagcccg aaaaatgagg gacaagttct gcgggtgcat gatttgtcac tattgcgttc
    11641 gaaactcccc atcgttctat attttctgat aaaatcttcg cacgtttcgg aaagatctca
    11701 ttcgtcacta ataacccttt ccccttcatt tgagcagcta attgggttga tttaccaccg
    11761 ggagccgcac acaaatccaa aactttttca ccgggttttg ctgcagcagc tgttccaacg
    11821 atcattgcac ttggttcttg gctatattca tacccagctt gatggaggaa agactttcca
    11881 ttgacagtgc caagaaatcc ctcattgctg tagggagcgg gttgtaattc ttcgctatgg
    11941 taagtttgga ccatgtccaa tcctgccggt tttagtggat tccaccgaaa tccttttttc
    12001 acgcttcctt gttcaagcgc agaaaaaaaa tcggatgctt cttcgcctaa aagaagacga
    12061 tattttttga taaattgctg tggtaacgtt gtcgcttcct ccttcattcc aatgtttcgt
    12121 tagacatttt acaatctttt ttacgaaaaa taaaggtggc tgatctactt tttcatgttg
    12181 ctgcctaagg tgactgttcc tttaagatat tttccaagta ttcatccgtc acctcgtttt
    12241 tatcccaaac agcgttcatc atttcaagaa aatcttgaga agaatcatct gagcgcaaac
    12301 ttcccaatgc attaagccat accaattcaa gcgacttttc ttctttgatc ttcgtgtgac
    12361 ctttgacata tgagaaaaat ggccgcttaa atagcgaatc catgtctaaa tcagattttg
    12421 caatgatttc acgaatactt tcatggatag aaaaaaaatc tttcaataag tagacaatgc
    12481 ttaaaacatc atcggaactg cattcagcta agtagttttc aaaataaaca gtgatttctt
    12541 ctaatatctt ctcttttaac ccgctgattg atttgaaatg tgtataaatc gggtatgtag
    12601 aacaaccgca gaactctgct aactctcttg cagtaattga cttcattcca tattcttcca
    12661 cgtataccat acttttgaac agcaaatatt ctttactata atttgttact ctccccatca
    12721 ttcttacctc cgtctctttt catctaccca taaataaata acataaataa ttctaaaaat
    12781 attattgata attatcaaaa catatttagt tatatccatt aaaaatcaat ttttccgcct
    12841 taaaaacaag aatatcttga caaaatac
//
LOCUS       DAZUJR010000082        12738 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.082, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000082 DAZUJR010000000
VERSION     DAZUJR010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12738
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.082"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(86..265)
                     /gene="rpmF"
                     /locus_tag="ACG804_002294"
     CDS             complement(86..265)
                     /gene="rpmF"
                     /locus_tag="ACG804_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HFS4833210.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(323..892)
                     /locus_tag="ACG804_002295"
     CDS             complement(323..892)
                     /locus_tag="ACG804_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HFS4833211.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1078..1980
                     /locus_tag="ACG804_002296"
     CDS             1078..1980
                     /locus_tag="ACG804_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HFS4833212.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="ACG804_002297"
     CDS             complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="ACG804_002297"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HFS4833213.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="ACG804_002298"
     CDS             complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="ACG804_002298"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HFS4833214.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="ACG804_002299"
     CDS             complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="ACG804_002299"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HFS4833215.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8548..8733
                     /locus_tag="ACG804_002300"
     CDS             8548..8733
                     /locus_tag="ACG804_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HFS4833216.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8795..9991)
                     /locus_tag="ACG804_002301"
     CDS             complement(8795..9991)
                     /locus_tag="ACG804_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HFS4833217.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10161..11597)
                     /locus_tag="ACG804_002302"
     CDS             complement(10161..11597)
                     /locus_tag="ACG804_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFS4833218.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11890..12699
                     /locus_tag="ACG804_002303"
     CDS             11890..12699
                     /locus_tag="ACG804_002303"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFS4833219.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3803 a         2673 c         2250 g         4012 t
ORIGIN      
        1 tattttttat ttaccgacta caaaaaaata aacctcaagg ctccatggtt agccttgagg
       61 ttttacattt tctaattaaa atgtattaag cttcttttga cattacgtcc ttaccatcat
      121 agtaaccaca atttgcacat acgtgatggc tttttttcat ttcaccacag tttggacatt
      181 cgtttaaccc tttgattgtc aatttgtagt gtgtacgacg ttttgctttt ttagcttttg
      241 atgttcttct agctggtact gccattttgc tacacctcct tgtaaagtct tgtatctaaa
      301 ttagacacaa tatattccaa tcttacttgt tatcgtcgtc ttttgattta gaatcaaaaa
      361 gttcagatag ttttgcaaga cgaggatcaa ttttattctc ggcttcttcc atttttctgc
      421 gctggtattc ttcttcggaa acaacttccc aatcattgcc ttttggaagt tctgttgctg
      481 cttcctcttc ttttgtcaat acccgcattg gaatcgccaa taagatgttg tcttcaatcg
      541 actctgctaa attcaataat ggaccttcaa ttagcaaaat ctcatctgca gacatttgtt
      601 catctctact ttggaattgt tcttctgtca tgaatacttc gtctacagaa aaatccatgg
      661 gcagttcaac aggttctagt gaacgtgttg aaggaactgt caaagtcgtc tgcacagtgt
      721 aatgaacgat atagcctttc ttatcaactg agaccaaacc ttcgacttcc actggcgcaa
      781 catcaagtat taaattgtct cgcttcatga gagcggcttt caagtcgagc gtctcatgaa
      841 aagttaacgg tgtctcctgg tattttctca attccaataa agaccatttc atttttcatc
      901 actcctaagc aacaaaagca attatacagg gcaaaaagca tgttgtcaat gaaattttct
      961 tgacaccttg cagttcataa aaaaacagaa aaatctttat tagaaagcct ctgtttgcta
     1021 tcatcctcag aatcatttac aataatcatt attccattaa aggagcggat gatcttcatg
     1081 aacacgaaag atatcgaata ctatgtccaa atcgtcaaac aaaaaaattt tacgaaagtg
     1141 gctaattatt tccgtgtgag ccaacctact attacatatg cattacaacg tcttgaaaaa
     1201 gagtttgaca ccgtacttat tacaagagat cgatcgcatc acgaattaat cgtcacgcct
     1261 tctggaaagc agctgtttct ccatgcacaa accattctcc aagagatttc tactgcaaga
     1321 gctgaaatca ctcagttgca aaagaaaaag cttcgttttg gcatgcctcc tattatcggc
     1381 aatgaatact ttcctaaact gtcaagttac tttatcaagc atgaattgat gaatcaaatt
     1441 gagattaccg atggaggctc tcgggactta tacgggatga tccgacaagg gaggatcgat
     1501 ttagctgtat taggctcaac acagccaatc gtggatcaat atttagaaac agagttactt
     1561 ttggacaaac gtttcatgat cgtcgtgcca cctacacatc ctctttccaa gcaggatact
     1621 gtctctttca aagatatagc agatgaacag tttgtactat tgaacgaaca ttatgtccac
     1681 cccgcagcat tcactaagct ttctaaacaa acacatactc atccaaaagt tgtttatcaa
     1741 agcaatgact tgacgatttt aaagagtatg gtccgagaaa atgtgggtat cggttttttg
     1801 gcagagattg ctgtccatcc tgaagatcat ttagtttgcc tccctctttc agatgaagtt
     1861 cagcctcgct tcttgatttc attggcaaaa cgaacacagc agatcgtcac gcctcttcaa
     1921 gaacaagtag tccaagttat ccatgaattc gttacagcac aaaaaaacag ctcttcgtaa
     1981 aagaagagct gtttttattt tttattaagc taaattagat agctgttgtt tcgccacggt
     2041 aaacgatgcc gcgacgtgaa tcaacggtaa tcaattcacc ttctgtaatt gttgttgttg
     2101 cgcctttagc accaacgatt acaggaatat cttgtgcaat tcctacaact gcagcgtgag
     2161 aagtcaatcc gccttcttca acgataacag cagctgcttt ttcgattgca ggcatatatt
     2221 ctttgtcagt tgatggtaca actagaacca ttccgtcttt tgcttttttt acagcttctt
     2281 cagcagatga agcaataact gcatttgcaa cgacagattt ttgtccaacg ccttgagctt
     2341 ctaataattt agaaccaatc atttgaattt tcatcacgtt agttgttccg cgttcaccaa
     2401 ctggtacacc agcagtgatc aagattaaat cgccttctga tgcgaaacct aattcaacag
     2461 cttttttagc tgctagttca aacatttcat cagttgttga tggtttttca gcaactgttg
     2521 ggtaaacgcc ccagtttaac atcaaaccac gttttgtgcg ttcgtcaaaa gtaacagcca
     2581 agatatctgc atctggacga tattttgaaa tcatttttgc agtgtatcct gattcagttg
     2641 cagcaacgat tgttttcacg cctagatttt ttgcagcacg agctacagat aaaccgattg
     2701 tttcagttac atctgtttta tcgaattcgt tcaattggaa tgtacctaat tctgataatg
     2761 cattttcagc ttcttggtcg atacgtgcca ttgttgaaac agcttcaact gggtagtccc
     2821 cgtttgcaga ttcaccagat agcattgttg catctgtgcc atcaaataca gcgttagcaa
     2881 cgtcagaagc ttccgcacgt gttggacgtg ggttttcttg cattgattct aacatttgtg
     2941 tagcagtgat aactgggata ccagcagcat tacatttttt gataatgcgt ttttgaacca
     3001 ttggtactag ttcagctggg atttcaacac ccatatctcc gcgggcaatc ataacaccgt
     3061 cagaaacttt gatgatttcg tcaatgttgt cgataccttc ttgagattcg attttaggga
     3121 agatttgaac atgagtcatg tctttttctt ctaagatttc gcggatatct agaacgtctt
     3181 gtgctttacg tacaaaactt gcagcgataa agtcgatatc gttgtctaaa ccaaaacgaa
     3241 tatcgtcagc atcttttgga gtaatacctg gcaaactaat agaaacgcct ggtgcattta
     3301 cccctttacg tgatcctagc atacctgcat ttttaacttc tacgactaat tcacggtttg
     3361 cttcgtcttt ttcaatgatt tgcatatcga tcaaaccatc atcaaataaa atgtgtccgc
     3421 caacgtgaac atcgtcaaat aatcctgggt aagtaaccgc gattttttct tttgaaccta
     3481 catgttcagg atccatagag atgcgtgttt gatctcctac ttcaaatttg atgtatcctg
     3541 cacgaccaaa atcagcttct gttgtgcctt gaacagttgt acggatttca gctccttttg
     3601 tatctaaaag aataccgaca tcttttcctg tctttttaac tgcttcacgg accatagtca
     3661 tacgtgataa ttgttcttca tggtcaccat gagaaaaatt aaagcggaag acatttgccc
     3721 cagattcaat caattgagaa ataatttcta ctgagttact tgctggtcct aatgtactaa
     3781 cgattttggt ttttttcatt taaaaaactc tcccattcaa ttttgtttat ttaaagctgt
     3841 acacagctta aatagcttgg tttctttcac tcttaaaatg aaagtgaatt atttagatca
     3901 tatagtgata agtctggttt atgtttgttg ttttcaagtg tatcaatgat gtcagacgca
     3961 acgatttcgt tgtcatggat accgacacat aatccacctt ttccttcttg aagcaattcg
     4021 acagcgtaag caccgaattt acttgccaac acgcggtcgc gtgcgcttgg tgctccacca
     4081 cggacaacgt gtcccaagat agatacacgt gtatgatagt caccaaattc tgaaagtttc
     4141 tcagcgaatt catttccgcc cattacacct tcagccaaga tgatcaagca atgtttcttc
     4201 ccgcgatcgc ggccttcttg gattttttta gcaactgaag ccatatcaaa atcatgttct
     4261 gggatgatga tttcatccgc tccgccagcc acacctgacc ataaagcgat gtctcctgca
     4321 ttgcgtccca ttacttcgat aacgaatgta cgaacatgag aagtcgctgt gtcacgaata
     4381 cggtcaattg attctagtac tgtattgatt gctgtatcaa aaccgattgt gaaatcagtc
     4441 ccaggaatat cattatcgat tgttccagga atacctactg ctgggaaacc gcgttttgtc
     4501 aaagccattg cgccatgata agagccgtct cctccgataa ccactagacc ttcgattccg
     4561 aattttttca attgttcgat tccttttaat tgaccttctt cagttgcaaa ttctggataa
     4621 cgtgcagaat acaagaatgt accaccacgt tggatcttgt cacctacatc tgccacatca
     4681 agacgacgaa tatctccagc aactaaaccg gcaaaaccat aattgatccc gtatacttcc
     4741 agtccttcgt aaataccttt acgaacaacg gcacgaacag ctgcattcat tccaggtgcg
     4801 tctccgccac tggtcaaaat tccgatgcgt ttcataataa acattcacct cattaaaata
     4861 ctttatccta agtatgactt aggtttacaa ccatttttgc gttaaccacg actaacattc
     4921 taacattatt tttctcactt gtcttgattt acggataaaa aaatgaaaaa aaatgaaagc
     4981 aagtagtatt ttttaccgta agttatttga aaaccacatt atcttcgcca agcagataaa
     5041 taagttgccc ctttatactc ttgctgtcat ccacccaata agcatctgac agaactactt
     5101 ttcgttgcgt tttttcgtga tacataacta ctggtatata tcctgggtgt ttctgaaaaa
     5161 tcacttgtaa ttgtttcatt atctcgggat cttcccgttc ttctgtaata cgcaaatagc
     5221 aagtttgtga aggatactgg gcttctaact ggttaggatc agcaaagctt tctccaatta
     5281 gttgcagttc ctgattatat ttgctgattt cgctccgccc ttgaacaaag atcactcgat
     5341 caacggcaaa caaattacga tatttacgat aaagagttgg aaaaactgtg acagaaattt
     5401 ctccactact gtcggttcct tcaacaaagg ccatcagttc tccttttttt gtccgaattt
     5461 ctctaacttc cttgatcatc actaataaat tgactggttg attagggacg atatctgtaa
     5521 tcagctgaac ttgtttagct aaacgaagac gatcaaaccc ttctgcagga tgacctgaca
     5581 aataaatacc taagtactcc tcttccagct tcaagcgttc ttctagtgta tagtcagcga
     5641 cttcttcttc ttttaatgcc atgattccca gcaagtcaag acttccacca ctgtaaacga
     5701 tattttggat ttttccttcg agatcaagca tcaattgttt cctgttagga gataattcat
     5761 caaaaactcc tactgctgtc agtgattgca gtaactctaa tttcagccaa cgcttatcga
     5821 tccgtatgag gaattgatcc actgactgga acgggccatt ttgttttctt tcgtttaata
     5881 tatcttctac aaaatcacgc cgaatacctt ttatcgctgt cagtccgaat ctgatttctt
     5941 ccttattgac caactcaaaa ctggaattac tttgattaat ggacggcgag gaaagtttga
     6001 gtttattttt acgtgcttct gcaatatatt ctttcaattt tgatgtgtta tgccgaacag
     6061 aattcatcag gctggtaaag aaagcacctg gatgatgggc ttttagatac gccatttgga
     6121 atcccacgaa tgaataagca aatgcatgtg accgattgaa tccatagttt gcaaattttt
     6181 cgatatattc atatacggtc gctgctgttt tttccgaata tccctgttgt aatgctcctg
     6241 atacaaaatg cgacttttct tcatctaata cgtctttttt ctttttactc actgcccgtc
     6301 gcagaatatc tgactgccct aatgtaaatc cagccatagt cgaggcgatc tgcatgattt
     6361 gttcctgata gacgatcact ccatatgtgt ttttcaaaat cgggatcagt gaatcatctg
     6421 ggtagcgaat ggcttctttt cctttcttcc tggcaatgaa ggtatctata ttttgcatag
     6481 ggcctggtcg atacaatgca ttgactgcgg caatatcttc gatgttttct ggatctaatc
     6541 ttcgtaaaac gttccggata ccagcagatt caaattgaaa tactcctgag gtttcgcctc
     6601 gttgaaacaa gagcagcgtt tttgcatcat ttagcgggat ctcttttaat cggatctcat
     6661 acccttctac tcgcttaaca gctttcaaag taaaatcaat aatcgataag ttgcgtagtc
     6721 ctaaaaagtc cattttcaaa agaccgattg cttctacctc attcatcgta tactgggtca
     6781 gaaaagcttc atcagaaccg cgttggagcg gaactagttc aagtagattc ttatcgctga
     6841 taactacacc tgctgcgtga gtcgaaacat gtcttggcaa tccttctaaa atcactgcag
     6901 ttttgaataa aagttggttt ttttcgcttg cctgaactaa ttctactaat tgatgcgaag
     6961 ttttataagc ttgggtcaat gtgattttca attgattggg tattgctttt gaccagcggt
     7021 ttgcttcact ttgcgataaa ccaaacactc tagctgcatc tctaagaacc atttttgctg
     7081 ccattgtgcc aaatgttgcg atttgtgcca tatgatattg tccatacttt tctcgaacat
     7141 aattcaatac ttcttcacgt cgattgtcag gaatatccaa atcgatatct ggcatcgtaa
     7201 agcgttcggg gtttaaaaag cgttcgaaca gcaaatcata ttctaatgga tccacatctg
     7261 tgatttctaa cacataggct actaatgaac ccgcagcaga accacgacct gcaccggtaa
     7321 cgattttgtt tctatgagca aaagccatta catcccatac gatcaagaaa taatcatcga
     7381 atcccatttg atggatgaca gataactcgt agtccaaacg ttcttggtat tcctttgtat
     7441 agtcagtgat tcggcgttcc acttgcgaat agcataactc tcttaaatat tctccagctt
     7501 gttttccatt aggaactgga taatgcggaa gtaatttctg atggaactgg aattcaaatg
     7561 aaatcgattc agctaaacgc tgggcgccta ttacagcttg ggaaagaccc gctttttcga
     7621 atcgtttgat catttcttgt tctgaaagaa gatagacatt tgctgttagt ggtaaagatg
     7681 cagataaatt ttctaaaggt atttggcttc cctctttgat atgtttcatc acttcaagtg
     7741 caaaaagttc ttcttgttgt aaactagcga tgggatgtaa tgcacaaagc gaataatttt
     7801 cttttatcac atactgatac cattcaggca attgatcagg cgtgttttct gtcaagccga
     7861 tataaaaatt tctagtaaaa acattttcaa gtaaaaactg ccaatgaccg aaaaagttat
     7921 cctctttatt gaaagcctca gaaacagaat gatttgccgg aacaacaaac gctagatggt
     7981 cggtttctgt catttctgca agttccaatt tttcttggat catttttcgg ctggaaagtt
     8041 tcatcagctg ctgataacct atttcatctt ttgcgtacgc aagcaagcca taattttttt
     8101 cttcataagt ataactaaga tgtaatccaa tgattggctg tactccttct tctacacaaa
     8161 tacgatagaa ttcaggtgca ccgtataaga catctttatc cgttatggct aatgaagtgt
     8221 agccttgttt ttttgcttct tgtacatatt ctcgaatacg tatcgtactt tgtaaaagag
     8281 aataagaagt aattgtataa agttgtggga aaaacatctt gcattccgcc ttttttttcg
     8341 ttaaaattca ctagcgttaa aaggtttgat ccttttactt tcattaagat agcaggcgct
     8401 gaagttgatt attccacttc atttgcttgc ttgtaatctg taggaatgag ttctttcgca
     8461 agaactcaaa ttttattgag atttggtctc gtttctttac attcaaagaa aatctggtaa
     8521 aattaagata gaaaagaggt gttctttatg cgatatatcg ttacattatt ctgggctgtc
     8581 gttctaggtc aagtagtcgg ttatattggt gctgcattaa caagcggaac atatgatttt
     8641 actttgacaa caatcatttc attcattgcg ggtgtcatta tccttttgat tggtgcagtt
     8701 gcgccaagaa aagaaacctc tgcccattcg taaaaaaaca gccaagagct tgagatttct
     8761 caagctcttt tttattttct actcctcacc accattataa tctgctgcga agaactttac
     8821 gaaagttgaa taaagaaaga agaatatttg acagaacaaa caaacttgtc acaataaaaa
     8881 cagcactgta attataagca tgcgcgactg tcgatcctag catgggacct aaaacttgtc
     8941 caaagttgct aaacatctga ttgtagctat agattcggct gactccttct tgaggcgtaa
     9001 tcttactgat cagtgtattg acagaaggca tcaaagcgcc agttgaaaag cctaaaataa
     9061 agcgaagtat acctaattgg agcggtgtag tgacgaatgc cataggtaaa taacagcaaa
     9121 atgataaaat gagtcctcca attagaactt tttgattccc aatcttatcc cctagttttc
     9181 ctagtttcgg tgaagaaaag acagcggaaa caccagctat cgaaacaatc aagccgctga
     9241 caaaaaggat attttctgta cttccgctca attcacgaat atataaggtc aaaatagggc
     9301 tgatcgtagt gattcctatc tgtaaaatca aggtcgtaat gaagagaccg atcaaaatag
     9361 agagatgatc catttttgaa aaaatttctt tggtgcttat cagatctttt ttctcgattg
     9421 gatggaaatc ttctttgact aagaaaatgg tcaataccgt tgtgatcatc aacaaagccc
     9481 ctgtgatcaa gaatacattt tccataccaa accactgagc cagtgcaccg cccattgaag
     9541 gtccgatcag atttccagca atcgctccgg tagacaatgt tcctaacgcc catccgctct
     9601 tttctctagg tgcctgtgaa gcaatcatcg ctgtggcatt tggaatatat ccagacaaaa
     9661 tcccattcca aaaccgcatg atcaaaagcc aatacgcgtt tggtacaaaa gccaaagatc
     9721 ccattgttaa tgtcatccct gctgctgcac ggatcatcat gagttttcgg ccttttcgat
     9781 cagctagatt tccccagatt ggtgcaacca cggcagatgc aaaagcagtc acagagattg
     9841 ctagtcccga aaacaattcg atttgatctt ttggtgttcc tagttgctca acataaactg
     9901 gtatgaatgg cataactaaa ctaatacttg caccagtgaa aaaacagcca atccacgcaa
     9961 tcactaaatt ttttctccaa ttaatctcca tctatcatcc ctctttcgtc tcttttatca
    10021 tacctatttt cgaataaaca agcaacgatc tcgccagtaa aaagagaaaa atcccgcaaa
    10081 ggtcatttta tatgtaacgt tctttttatg taaaacaaaa agagatcaga acaaatactg
    10141 ttccaatccc ttctctttag ttaaattgtt gctagaatga tgaagttgat aatgaataaa
    10201 atatcaacga tccacaaagc aacagaaact tgattgtatt ttcctttgat tactttcaca
    10261 attgtataga aaataaatcc tgctgcaatc ccataggaaa tgctatagca caatcccata
    10321 aagatcgatg caaagaaggc cggtaaagct tcttccatat ctagccattt gatgtctgca
    10381 aaagaagcca tcatcattac tccaactaaa atcaatgctg gcgcagttgc ttgatttggt
    10441 acaatggcga tcagtggaga gaataaacta cttaatgcga atagcactgc cactactact
    10501 gaagtcaaac cagtacgtcc accggccccg atcccagctg cagattcgac ataagttgtt
    10561 gtattcgatg taccaaagat agcccccaca gaagtagcga tcgcatcggc aaatagtgct
    10621 ttatccattt ttgttttgaa cccacgacca tcttccaacg cgatctcgtc ttcttttgag
    10681 aaaatacctg tgcggcgtcc tgtaccgata aatgttccga tcgtatcgaa agtatcagat
    10741 aaactgaatg cgatgatcgt catcaatact tgaggaatct tggaagaatc actgaataaa
    10801 gattgcatgc cttcagaacc aaatgctgca ccgaaagttg ttcctaattc tttaaatgaa
    10861 ttacctaacg aattcgtttg ccaatcaatg gaacttaaat caacaacacc cataaaaata
    10921 ccaaggactg tggtcgctac gataccgata agaatagccc cacggacatt ttttacaact
    10981 aaaatggctg tcagtaccaa accaatcaca gccaataaga taggagcgtt gtcaaagttg
    11041 gctaacgcag ggacgattcc accatttatc gtaacatttg tcgcttttcc gccttcaacg
    11101 acagagctcg aaatagctga ctggtctgct gaaaaagata agaatcctgc atttttgatt
    11161 ccgacatacg caacgaaaat accgatcccg ccaccaatcg catgttgaag actttcggga
    11221 atcgcccgaa taatcatttt tcgaatattt gtgacagtaa taaaaatatt gattaatccg
    11281 caaataaaca ccattgccaa ggcttgttgc caagaataac caagcccaaa aacgaccgta
    11341 aaagtgaaaa atgcgttcaa tcccatacca ggtgcctgag catatggtac atttgcgaac
    11401 aatcccatta ccagcgtacc aataatcgat gcaatgattg tcgctagaaa tactgcttgg
    11461 aagggcatac ctgatgctga caaaatcgtc ggatttacga ataagatata actcatggca
    11521 aagaatgtcg ttactcccgc cattatttca gttgatacat ttgtattgtt tttctttaaa
    11581 ccgaaaaact tttccataaa aagttccact ccctgaattt ttttctgatg gaaaactata
    11641 ataataaaaa ataagtaaaa tagggcaaat ccatcgaaca atttcaaatt atatagacgt
    11701 ttcattcgct tttcaacgtt tttttaacaa aaaaagcgaa aataatactt aacgttcgtg
    11761 tttagcttat gtttagctat ttatatagcc ataactgtag tttttgttag gaatagctga
    11821 ttgctcttgt taattaccta aaatatgcta gactaaaaca aatgctagtt gaggaaggaa
    11881 ggacccttat tgaataaaaa attaattgcc atcgatctgg acggaactac cctcaatcaa
    11941 gattcgatga ttacatctaa aacaaaagag actctaaaaa aagcaatcaa tgccggtcat
    12001 catgtcagta ttgctacagg acgcccattc cgaatgagcc atcagtttta ccaacaatta
    12061 gaattaacaa caccgatggt taattttaac ggcgcattag tacacatccc taatcagcac
    12121 tgggatggtg aaagagaaac gttgatcaat cgtgaaatcg cttttgaaat cttatcgcaa
    12181 aaaaagcagc taaatttaga ttttatcgct gctgaaaatc gtgatacttt ttttattgac
    12241 agttttgatt tctttgatga aaaaattttt gcttcttctc gtccaggaga gaagaatttg
    12301 ctttctccta aaaatttgac gacaaatcct acatctttgc ttgtccgaac agacaaacgt
    12361 tttgcaggag ctgtatctgc tgaattaaca cgtcaatttg gcagttatgt cgatgttcgg
    12421 acatggggtg gacctactgc catcttagag attgtttcaa aaggaatcca aaaagcaaaa
    12481 ggcgtgcaag agattgctaa ctacctgtct atcgatcaaa aagacgtcat tgcctttggt
    12541 gacgagcata atgatttgga attgttggat tatgcaggtt ggggagtagc tatggctaac
    12601 ggtactgacc aactcaaagg cattgcaaat gatgtcactc ctttgagcaa tcaggaagac
    12661 ggtttagctg tttatctgga aaaactactt aaactataat agagaattag attccacaaa
    12721 aaagaggttg tgacaatt
//
LOCUS       DAZUJR010000083        12503 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.083, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000083 DAZUJR010000000
VERSION     DAZUJR010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12503
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.083"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..222
                     /locus_tag="ACG804_002304"
     CDS             <1..222
                     /locus_tag="ACG804_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HFS4833220.1"
                     /translation="TEHRTIKYLNNLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIR
                     GLYKKTRKEGTLFGFSVCTEIKVLLGIPA"
     gene            274..843
                     /locus_tag="ACG804_002305"
                     /pseudo
     CDS             274..843
                     /locus_tag="ACG804_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010769338.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            1244..1849
                     /gene="fic"
                     /locus_tag="ACG804_002306"
     CDS             1244..1849
                     /gene="fic"
                     /locus_tag="ACG804_002306"
                     /EC_number="2.7.7.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_function: GO:0070733 - AMPylase activity [Evidence
                     IEA];
                     GO_process: GO:0018117 - protein adenylylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein adenylyltransferase Fic"
                     /protein_id="HFS4833221.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
     gene            1865..2437
                     /locus_tag="ACG804_002307"
     CDS             1865..2437
                     /locus_tag="ACG804_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFS4833222.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(2689..2946)
                     /locus_tag="ACG804_002308"
     CDS             complement(2689..2946)
                     /locus_tag="ACG804_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833223.1"
                     /translation="MANLYIENKGDLNAIITLIVVMVKSIGNITIGMLFIILAAVLIF
                     MIVIWFLNERSKDNQHRRDMEIKSIESIDYLSIITLKKPRS"
     gene            complement(3072..3887)
                     /locus_tag="ACG804_002309"
     CDS             complement(3072..3887)
                     /locus_tag="ACG804_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4833224.1"
                     /translation="MVKIAGLSKGGKTVSQLYKQNYRDWRQFRKNIKDSYFILPTELE
                     KYLPNNKAINLYLYYCFKAKNEGGDSWHSVNTIAESLGVTTKTINTWNKTLVDLGMIA
                     RIDDNHLSKSTILLPLSSYYKLALDSSLKDVTESTVHEIDGNLVAVYHLFEWRKNEAD
                     ENYNVPYNTLCCVFKRKTQKDTIYKFILVQDEKISNFELSTPSSKIYDDAYRFECQDL
                     EALLSANNLNNIEHENFVVNTRFNLVSEKDSDLLDLLIELTKNLDKKENITVL"
     gene            4404..5729
                     /locus_tag="ACG804_002310"
     CDS             4404..5729
                     /locus_tag="ACG804_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HFS4833225.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSMNLFTTEGTRSQRRKKLAQMIQENIKEELGLLA
                     TVGVGDNPLLAKLALDNEAKHNDGFLAEWTYQNVPDKVWNIPEMTDLWGIGSRMKKRL
                     NQIGIMSIKDLANWNPYTIKSHLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLYIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
     gene            5722..6072
                     /locus_tag="ACG804_002311"
     CDS             5722..6072
                     /locus_tag="ACG804_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833226.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEKIDADNEQRANQNLAKEQMTTE
                     EVAEVLNAAVIKNRSVCIQKEERNAEGYYPEDIVSKILGSDELGIYVGKNKVHYDEIR
                     HIEFYQDNKWGRLE"
     gene            6069..6239
                     /locus_tag="ACG804_002312"
     CDS             6069..6239
                     /locus_tag="ACG804_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833227.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHKYEYYIGY"
     gene            complement(7143..7418)
                     /gene="prgO"
                     /locus_tag="ACG804_002313"
     CDS             complement(7143..7418)
                     /gene="prgO"
                     /locus_tag="ACG804_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA segregation protein PrgO"
                     /protein_id="HFS4833228.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(7390..8343)
                     /locus_tag="ACG804_002314"
     CDS             complement(7390..8343)
                     /locus_tag="ACG804_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFS4833229.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            8955..10448
                     /locus_tag="ACG804_002315"
     CDS             8955..10448
                     /locus_tag="ACG804_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HFS4833230.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            10583..10879
                     /locus_tag="ACG804_002316"
     CDS             10583..10879
                     /locus_tag="ACG804_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HFS4833231.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
     gene            10980..11831
                     /locus_tag="ACG804_002317"
     CDS             10980..11831
                     /locus_tag="ACG804_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833232.1"
                     /translation="MKSDDWIEHNWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILF
                     FVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKG
                     IRSILKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDL
                     ELPMKDK"
     gene            11852..12064
                     /locus_tag="ACG804_002318"
     CDS             11852..12064
                     /locus_tag="ACG804_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833233.1"
                     /translation="MIPLYRIVLIVGMELKTLKKEQLFKVKERHNQLLCSKTGTMNIE
                     YRTEYLELTNQTDFLLIRKQQEQEKN"
BASE COUNT         4303 a         1927 c         2335 g         3938 t
ORIGIN      
        1 acagaacatc gtaccattaa atacctgaat aatttgattg aacaagacca tcgtccagta
       61 aagagacgca ataaattcta tcgaagttta cgcactgcct ctaccacgat taaaggcatg
      121 gaagccattc gaggattata taagaaaacc cgaaaagaag gcactctctt cgggttttcg
      181 gtctgtactg aaatcaaggt attattggga atcccagctt aaatcataga taccgtaagg
      241 gattttattc tttatttaaa actttgcaac agaacctatt attttaagtc tgaaaaggat
      301 acatcgtctc taacgttaac tttagaggaa ggagttgaac ctgacaaggt gacctctaaa
      361 gtgataaacc aattgaaaga aaaaggtagt ttgaaacatt tgggggaata tgaagtgtta
      421 gatacggcta tgttaacgaa aggaattggt caaatcctca gtacgatcac ttattttata
      481 acagctgtag caggtatatc tttatttatc gcaggggtag gtgtaatgaa catgatgtat
      541 atatctgtat ctgaacgaac aaaagagatc ggtataagaa gagccctagg agctactcga
      601 aaatcgatta tgctgcagtt ccttttagaa ggtttgattt taactctttc aggagggtta
      661 attggctatt tattaggaat ggctcttgct tatagtgttg gttctttgat aaaggtaaac
      721 gtgtcacttg atctatttac tattttacta gcggttgggg tatcttcggt tattggactg
      781 gtcttttctg taatgcccgc ttcagaggct gcaaaaaaag atttaattga tattcttaga
      841 taaaatcaga atgacaagaa tatttacgtt ctagattcta aaataaaaca caaagagacc
      901 aaccaggcac cctattgttt ctttgtagta tagagatatt ctttggcttg taagagatca
      961 atagagttag gtgaccggag ttcgaaataa aggaaatttt tgattgtata ggagaattct
     1021 ttatccctaa tatttagaat tttgagtatg ccatgttgat gttttagatt ctctataaat
     1081 atagaggtgt atcaaaggtc aactagactg tgcaaaatag agacacttga aaaatctatc
     1141 gggggtcaga aacttaatag tttttgacac ataaacaaaa tcgcgatata atggggttga
     1201 gagtgtttca taaacttatg tcataaagtt aaggagattt cgcatgattt tagagaataa
     1261 attgggatta accaatcaag ttgagttggc taaggttgaa gaaaaactca gtaaacaaaa
     1321 agcgaaagaa ttgtacgatt gtggaaaaat aaatgaaatc gaagttggta catttaaagg
     1381 tttatctgaa attcatgaat ttctattttc ggatatttac gattttgccg gaaaaatccg
     1441 atcggtcaat attgcaaaag gaaattttcg atttgcacca gttatgtatt tagaacattc
     1501 gttacagcat attgatcaga tgccacaaac ttcttttgaa gagattatca agaaatatgt
     1561 ggagatgaat atcgctcacc catttcgaga aggaaatggc cgaagtacta gaatttggct
     1621 ggatctcatt ttaaaggaag aattgcaaaa agttgtagat tggaacttaa tcgataaagc
     1681 agactatctt tctgcaatgg agcgaagtcc cataaacgat ttggaaatac gctatctaat
     1741 ttccaatgct ctgactgata aaattgacga tcgcgagtta tatatgaaag gaatcgatgt
     1801 cagctatttc tatgaagggt attctgagta tacgatagat gatttgtaaa agtaggtgga
     1861 ccaaatgacg aaatatggat atgcacgtgt ctcaaccgct tctcaaagta caaaagaaca
     1921 aattcaacag ttgcttgaga acggcgtaga gaagaagaat attttttcag aaaaatttac
     1981 gggtacaaaa cgggatcggc caaaattcaa tcagctgttg gctggtctga agcctggaga
     2041 tgaaatagtt gttacgaagc ttgatcgatt tgctcgtaac acgagagaag cattagagat
     2101 cattgaacct ttactcgatg ataacgtaac gatcaaggtt ttgaatctag gaacgattga
     2161 aaatacgtcc atggggcgaa tggtgacacg gacgttgttg agtgtagcag aaatggaacg
     2221 tgatatgatt gtggaacgta cccaagaagg aaaaatgttt gcaagaaaga ataatcctaa
     2281 tttcagagaa ggacgtccga aagcaacaat cacaccgaag aagaggcacg catatgaact
     2341 gcttacttca ggtaaatcgt ataaggaagt tgaagctata accggtttca gtcgcagtac
     2401 gctttttaga ataaagaaga aaattgaaga aagttaaaaa agaagtctca gcgaaccaga
     2461 caggtaaata cttaatgcgt tctagatatg agtctattag catgttgtga aatataatat
     2521 ttttttattt acttgatttc tgctcaaaaa atgtgtatgg taactgtaaa aggtaaagta
     2581 attaaaggta tgctagccac gcttactata ttaggatacc atcatatatt tataatgaac
     2641 gatttgttcg tctaccaaac aacacatatc gttcagcgta agtcacgttt aggaacgtgg
     2701 cttttttagt gttattatcg ataaataatc tattgactct attgatttta tctccatatc
     2761 cctacggtgt tgattgtctt tagatctttc atttaagaac caaataacta tcataaaaat
     2821 cagcactgct gctaatataa taaacagcat tcctattgtg atattaccta ttgattttac
     2881 cataactacg attaaagtaa taatggcatt caagtctcct ttgttctcta tatataaatt
     2941 agccataaat catcttcctt tcaaattaag atacttgttt gataccaata aatagtaagc
     3001 gtggctagca tacctttttc tgtaatagca agtgttctaa tagtccaaac ttaatgatgg
     3061 accgatgcta gttatagtac agtaatgttt tctttcttat ctagattttt agtaagctct
     3121 atcagcaaat ctaacaaatc tgagtccttt tcagaaacta aattaaatct agtgtttaca
     3181 acaaagtttt catgttctat attgtttaga ttatttgcgg aaaggagggc ttctagatct
     3241 tgacattcaa atctatatgc atcgtcataa atcttactag aaggagtgct taattcgaaa
     3301 ttacttattt tctcatcttg gaccaagata aatttataga tagtatcttt ttgtgttttt
     3361 cttttaaaaa cacaacagag tgtgttataa ggaacgttat aattttcatc agcctcattt
     3421 tttctccatt caaacaaatg ataaactgca accaagttgc catcaatttc atggacagtg
     3481 ctctcggtaa catcctttaa agaactatca agggctaatt tatagtaact agagagagga
     3541 agtaaaattg tcgatttact gagatggtta tcgtctatac gtgcaatcat acctaaatca
     3601 actaaggttt tattccaggt gtttatagtt ttagttgtca ctcctagaga ctctgctatg
     3661 gtattgaccg aatgccagga atccccgcct tcattctttg ccttaaaaca gtaatacaga
     3721 tataaattaa tagctttgtt attcggtaaa tatttttcaa gttctgttgg tagaataaag
     3781 taagaatcct taatgttttt tctgaactgt ctccagtctc tgtagttttg tttataaagt
     3841 tgtgaaacgg tttttccacc tttagaaagt cctgctatct taaccaatct tattgctcct
     3901 ttcttgaatc tgtcatgatc atacagtatt ttttacttgt agtccagcac cttaatatat
     3961 tatcctatgt aattaatttc gtactagata gtaattattt tttatttaat tctctagtca
     4021 cttacaaata agttatataa actacgatta ataaattatt acaaaaacta ttaagaaaac
     4081 ttctacatac aactattaca aaactattaa gaaactgaat actcctattt tttgttttta
     4141 aggaaagttt tttctttttt gaatttctta tttttttcta atataactaa gcaaaactgg
     4201 ataatacgac acttattttc aaattttcac aagactaata gtaaatatcc atttaataaa
     4261 gtgatacaat gtgttgattt tacaaatcaa cagaagaagt agggaaataa cttacctatg
     4321 cttctttttt tgtacattta atcgattctt ctttacaaaa acgaacgtat gtttgtataa
     4381 tgtggaagaa tggagtgtta tttatgatgg attattcaaa agagccagta aatgattact
     4441 ttttgatcga tatgaaaagc ttttacgcaa gtgtcgaatg tatagaaagg aatttagatc
     4501 cattaacgac tgaattagtc gtcatgagtc gagcggataa tacaggatca gggttgattt
     4561 tagcttcttc accagctgca aagaagaagt acggtatttc taatgtcagt cgaccacgag
     4621 atctaccgca accttttcct aaaacgttac atgtcgttcc accacgcatg aatctctata
     4681 ttaagcgaaa tatgcaggta aacaatattt tcagaaggta tgtagcagac gaagatttat
     4741 tgatttactc gatcgatgaa tcgatcttaa aagtgaccag atcaatgaat ctttttacga
     4801 ctgaaggaac aagaagtcaa cggagaaaga agctggctca aatgatccag gagaatatta
     4861 aagaagagct aggattgctt gctacagtag gtgtcggaga taatccctta ttagctaaac
     4921 ttgctttaga caatgaagca aaacataatg atggattcct tgctgaatgg acgtatcaaa
     4981 atgttcctga taaagtatgg aatattcctg aaatgacaga cctttggggt attggatctc
     5041 gaatgaaaaa aagactcaac caaattggta tcatgagtat taaagactta gctaattgga
     5101 atccatacac tattaagagc catttaggtg tgattggctt acagctgtat tttcatgcga
     5161 acgggatcga tcgaacagat atagcgatcc caccagaacc gacaaaggaa aaatcatatg
     5221 gtaattcaca agtgttacca cgagattata ccaggagaaa tgaaatcgaa ctggtggtaa
     5281 aagaaatggc ggaacaagta gctattcgta tcaggcaaca taactgtaaa acaggttgtg
     5341 tccatttata cattggcacg tcgatcttag aaacgagacc aggtttttca caccagatga
     5401 agatccctat aacagataat acaaaggaat tgcagaatta ctgtcttttc ttgtttgata
     5461 agtattatga aggacaagaa gtaaggcacg ttggaataac ctatagcaag cttgtgtaca
     5521 ctgattcgct tcagctggat ttatttagtg atccacaaaa gcaaattgac gaagaaaatt
     5581 tagataaaat tattgacaag attcggcaaa aatatggttt tacgtcgatt gtacatgctt
     5641 cttctatgtt agaaggcgct cgtagtatta ctagaagtac attggttggt ggccatgcag
     5701 gcggcgcagg agggcttaaa aatgattgat tataatgatc gtggacgttt aaagtgggca
     5761 ggtttttatt tatctgatca tactgaaaaa attgatgccg acaatgaaca acgagccaat
     5821 caaaatttgg caaaagaaca aatgacgact gaagaggttg cggaagtatt gaacgctgca
     5881 gtcataaaaa atagatcagt atgtattcaa aaagaagaac gaaacgctga aggatactat
     5941 ccagaagata ttgttagcaa gatcttaggt agtgatgagc tggggatcta cgttggaaaa
     6001 aacaaagttc actacgacga aatacgtcat atcgaatttt accaggataa taaatggggt
     6061 cgattagaat gaacattatc cagcaatatg agctaaagta tataaccttt gatcagctat
     6121 cagaagagat ttggggttat ggccagcgtt tgataaatga ggttggtgtt gaacgcttct
     6181 ctttctatgt agaagctgca gcaggatacc ataaatacga atactatatt ggctattaaa
     6241 gtgcaataaa attatatttc ttttatgttt tacattttgt atcaattctg ataaaattac
     6301 ctataggtaa ttaaaaaata taaaaaaact agttacaacc ttaggacgtt gtaactagct
     6361 tgaagcatac tagagctaac taaaatagca ctagaaagca atgttaaacc cgtccaacaa
     6421 acttgattta acattgagac cagcttattc agctaaatat agttgaataa gcttcttttg
     6481 ttttaaaaaa acaaaaggtg tactacgaat aacgcaagta aaagaaatac tattacaacc
     6541 agtaggctac aagtaagtat tactaaacat tgcgtagtta gaacctttgc tctattgtct
     6601 aaagccacaa aattagagat cagctttatg atgctaagag cgagctgcat ccatgcggac
     6661 ataggttctt ttgacactat taattctcct ttttaggata agggaaattg ctagtagttt
     6721 tttcattagc accatccccc ttcatttgat tgagtctagt gctgctgtga tagtttgctg
     6781 tttaatatgc ttacattctt attataacat aaatgaaaca aacacatggt tagaggtcgt
     6841 atcaatcaaa atagtgtctc acaaacgatt tattacttac tcctgctgac taacggactg
     6901 ttcttcagta actgtaacta tatgtttgtt aaaaccacca ttacctgtag ataaaaacca
     6961 atatatttac tatactcact atattaaata tatttagtat agtaaaaact agaaacaata
     7021 aaatttgtga atgttgtata cccccaaaca atacacatat tttgaaggat taggattaat
     7081 aaagctaaaa atatagtaag tatactaaat atatttacta tatctagtat acttactata
     7141 ttttaatctt ttgatcgtct attatatata atccgttcct cgtcgtttaa agtatcaaca
     7201 taggcgtcca ttgcaagttt gactatttca tacataggaa tatcttttgc ataactaaga
     7261 tcccgaatgg tttttagtac gggaggatct acttgaactg gttttctttc tttcgcagtg
     7321 tactttcgtt cccctaactc gacattaata tcatctttaa ttgaaatatc ttcagcacca
     7381 attttcttct tatctttgtt cgttggtaat aatgccattt agtttaatct cctttccaag
     7441 aggtaggata tgattggcca ttgagtcagc atatttaggt gtataatcaa atccttcaat
     7501 atcaccatgt tgttcatagt attcaattct ttcttctaat tctgtaaaga tgtctgcaaa
     7561 aatagcccac catcttcgat ctacataatc atttaattgg ataccattct caccatacat
     7621 ttctaaccga tccgagcctt taacaatgct tttaaaaatg tttgattcac catacttatc
     7681 aattgttttt tgatagtttg cgtgttgaga ggaacgtcgc actgagaaaa gaacaggcaa
     7741 aattccaatg atttgaagat gagactcttc aaaattcgtg acaatcggaa ctaaaacttt
     7801 attaataaaa tcttctgttc cttccattgc gtaccgtttt aattcttgca ttgcaataat
     7861 ataatctgca gcagttaaga atgcacgaac cacattatct gttgatggtg ggcagtcgat
     7921 aaagatataa tcgaaatttt ttctcaattc ttctaaaggt ttaatgaagg ccaatgatct
     7981 cttacgacga tcaggatatt tttcggacaa gtattcatta agttcttcag atccaggaga
     8041 gccagccata atatataaat gtggacttac ttgagtaata cctgaaaccc agtccccttt
     8101 tttgattgct gcagacatgg atcgatcaaa gctagtaatt tgatacgttg atccaatgtt
     8161 ggaagtagta tttctttgtt ggtcataatc aattagcaac acgtcttttt caaaaagttg
     8221 actagaaaca atcgctaata aatcattgtc tgtagtctta ccaatgccgc cttttctacc
     8281 tgtaagcatt acaacttttc ctagtttatc tgatgtttta aatgcagtcc gtaagttttc
     8341 catagttccc tccaatttcc tatactaaat atatttagta tacttcatat acttaatata
     8401 ttcgatatat ctaatatact ccaaattgat aagaattcag actttataag gaatatagtg
     8461 gatatactaa atatatttgc tatattcagt atatcagata tattcaaaat gtcaaaatat
     8521 atttgtgcgt tttgcgttga caatttagag tgaaaagagg taaacttaat tctatagaaa
     8581 ccacagataa ttcactattt acaaagtagc aaaagcagtg gtactcttta aacagaaaaa
     8641 ttacataaaa aaaagagacg gaaataattg attttagcag aatcaattat ttctgaatca
     8701 catggttagg acatgtgttc acgctcgtct caagaatatg taagtagcta ccaactactt
     8761 atattaaaag ttgatcggat accttttccg attgccttta ttctaccaaa aaaaggcgag
     8821 caactcaaca gaagaacgtt tatttagtgt acttaaatta aatattctta aacactgaag
     8881 agagaacaca tactatggct gagattaaag ctaaactgtg ttctcttttt gtttgagaaa
     8941 ggacgttaca atcgatgttg agcgaaattt attcagctat tcttaaaaac ggcttacgta
     9001 catacaaata tcgaaacagc accatgaaac ctgcaggtca tattgattcc agtaggagtg
     9061 gtgctatctt tgcgtaccgt agcaagcaat taatgaatgt tgggcgtggt atggtcatta
     9121 cttcggaaga agctatttta gagaacgaaa agaaactaac gcattggaca cctaatacct
     9181 atcgctttgg tacttatgcg gatgattatc gaacagtggt taaaggtcat tctgagaaaa
     9241 acttaagtca aatcaacaca tttgtagttg atatcgattc aaaagagaac catcaaggcg
     9301 aaattatttt agcctgttta gatcaagtgg gctacatgcc aacgctaatt ttagaatcag
     9361 atcatggtta tcaagtttat tttgtactaa agacaccagg ctatgtcaca aagaaaagca
     9421 atttcaaggt gatcgatgta gcaaaaaaaa tttcaaaaac aattcgtcta cagttggctg
     9481 aaaaattgtc cggagtggat ctaggatgta accacttcgg aattgctcga ttcccacaag
     9541 aaaataatat tgtttttaaa gaaatgaact atcagtattc ttttgctgac tggattcaat
     9601 ggtcgatgaa gcttgaatca gatcaaaaaa caaaagaaga tcgagaacga aaactaattg
     9661 tctttcctga gaaaaaagaa attcgtcaag tagatgaacc gtggttcgat atgttacttc
     9721 ataaagcaaa catcgtcggc ggagaaggac gtcttggtcg aaataatgtg attttcacgc
     9781 tttctttagc ttattactct tcaggttatg cattggatac ttgcgaatac aatatgttca
     9841 cattcaacga acggttacag gaaccgctat ctgaagcaga attagtaaag attgtacgta
     9901 gtgcttattc tggtaattat caagcagcaa gcagagaatt cattattgaa ttgtgccagc
     9961 aatgggtttc accaacctta aaaaataatg atctgttcat tcaacgacgt ggctggtgga
    10021 aatttaaaaa gccacgagat caaagaaaat atagtcataa aaatgaatgg aaagaagatc
    10081 tattggctta tctaagcgaa aaaagtcttg ctagtgagcc ttatttgaac ctgtcaaaaa
    10141 aagaattggc ttcacaacta acgatgccca agcgaacact tgataagatc ttaaatgagt
    10201 tacgagagga gaataaagtc ttctacaagg taacacgagg aagaaatggc ggaatgatca
    10261 ttgcttcagt caaaacgttg ttcgcgaggg ttattcaact aagtaaagaa aagagactag
    10321 attattcaac aaggatcaca gaggtatttg gactcaacga gagcttagta gaagagacat
    10381 ttagacaatt atcaaccccc ttgaaccctc ttaaagaagt gaatcttttt gaagtagata
    10441 caggttgaaa aataaaaggt gcaaattgcc ttatacaata tatctatgat acttctgtag
    10501 gtgttgctcc ctttgcctag ctacgtgtag gtggtatact tataactgcg tatgcagtct
    10561 tatgtatcat ggaggaagtt gtatgtcgtt aaaaaattat gtctattcac atcctgttaa
    10621 tgtgtttatc attggtcgtt tgggattatc tgtggaagtg ttctgtgagc tttatggttt
    10681 taagcagggg actttgtctt cttgggttac cagggaaaaa acagttgctt ctttgccgat
    10741 tgagtttctt catgggttgt ccttagcttc tggggagact atggatcagg tatatgattg
    10801 tttgtgtgtg ttagagcagg agtatattga gtataaaata gctaacgagt taagaaaaag
    10861 gaagaagtat atccagtagt agtttttatt tacttaaaaa attggttcat tgagcaacct
    10921 atcgctgcta aagtagcaaa ggaaaacgtt aaaggaaaga atttagggaa gaaatcgaaa
    10981 tgaaatcgga cgactggatt gaacacaact ggcttcctct gaaaagaaat agcaaacgaa
    11041 agaaattttg ggtattgcaa ttatggccat taggaaaact ttgtagttac ggggcacgac
    11101 ttattcttga tttaaccgtt tactcgattg gagtatttgg aacggcttat tacttgataa
    11161 atgatcccaa taggattgca gcatcagaca tttttacagt gctaatgacg ttgatttttg
    11221 tcatgctatt gtctattttt actcaattag tcatgcaatt taccaggcaa aaattaacag
    11281 caggaaaact tttcaaaagc ctattcgatt taattgttgt aaatgcaatt ctagcgactt
    11341 taataaaaca aattgaacaa tctggaagaa caacaaaagg agtgaaggat tttttattga
    11401 cgtttattca ctttgtaaat ggacacatgt atttgtttga agtgggtatt attctctttt
    11461 ttgtcgggta tgtatccacg aaacttatta aacgttcaat tgaaaaagaa attgaaattg
    11521 acctgattcc gacacttctt ggttatgagt acaatgttga ttttggaaga tatgacgaat
    11581 tgatcaatac ggatatcgtt cacacgagta tccatgaatc tactgttaag ggcatcagat
    11641 ctattttaaa aaatggccag gaaatgaaag caatagatcg aagaaaagag atctacaatt
    11701 tttatgaagt cgaagcaagc ctacgatatg gcatcggaaa attgtggtta gatggaagta
    11761 atattcgtca aaacaaacca tacatttttt ggaacagtag tgatttagaa cttccaatga
    11821 aagataaata attatggaga atcgtttgaa aatgattcct ctatacagga ttgtgcttat
    11881 agttggcatg gagttaaaaa ccttaaagaa ggagcagtta ttcaaagtga aagaacgtca
    11941 taatcagtta ctatgtagta aaacgggtac gatgaacatt gaataccgaa cagaatattt
    12001 agaattaacg aatcaaactg attttttgtt gattcgaaag caacaagagc aagaaaaaaa
    12061 ttaatggcta cttatagcca attgattgat gaatgggaac aattcaagga atctaaaatt
    12121 ccagaacgtc tctaaaagcc tttatttgta aagagcataa ggaaacgtgg gaacactttt
    12181 taaaaaaagt gttccaatag gctgtgccta ttacgtttct caaaaataaa tgtgggaaca
    12241 aaatatttaa aaataggata gtgaaaggat agtgaaggat agtaaaagga gggtagtagg
    12301 atagcaaaaa ggataggctc cttttcgcta tcctttttaa attggaggaa ttaatatgga
    12361 agtaagaata agaaatgtgg atgagaaaat cgtaagagaa attgatcgaa gatgtgacga
    12421 acggttctgt tgcaaagttt taaatctact atcaaataag gtagaataat agaaaaagat
    12481 agcaggagga atgacgatga atc
//
LOCUS       DAZUJR010000084        12125 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.084, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000084 DAZUJR010000000
VERSION     DAZUJR010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12125)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12125)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12125
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.084"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(87..251)
                     /locus_tag="ACG804_002319"
     CDS             complement(87..251)
                     /locus_tag="ACG804_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833234.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            546..1874
                     /locus_tag="ACG804_002320"
     CDS             546..1874
                     /locus_tag="ACG804_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HFS4833235.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            2076..2909
                     /locus_tag="ACG804_002321"
     CDS             2076..2909
                     /locus_tag="ACG804_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HFS4833236.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            2925..3662
                     /locus_tag="ACG804_002322"
     CDS             2925..3662
                     /locus_tag="ACG804_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HFS4833237.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(3817..4785)
                     /locus_tag="ACG804_002323"
     CDS             complement(3817..4785)
                     /locus_tag="ACG804_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HFS4833238.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            5017..5850
                     /locus_tag="ACG804_002324"
     CDS             5017..5850
                     /locus_tag="ACG804_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HFS4833239.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            5884..6723
                     /locus_tag="ACG804_002325"
     CDS             5884..6723
                     /locus_tag="ACG804_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFS4833240.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            6749..7309
                     /locus_tag="ACG804_002326"
     CDS             6749..7309
                     /locus_tag="ACG804_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFS4833241.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            7508..9229
                     /locus_tag="ACG804_002327"
     CDS             7508..9229
                     /locus_tag="ACG804_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HFS4833242.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            9394..10536
                     /locus_tag="ACG804_002328"
     CDS             9394..10536
                     /locus_tag="ACG804_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HFS4833243.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            10552..11763
                     /gene="thiI"
                     /locus_tag="ACG804_002329"
     CDS             10552..11763
                     /gene="thiI"
                     /locus_tag="ACG804_002329"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HFS4833244.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
BASE COUNT         4130 a         2035 c         2520 g         3440 t
ORIGIN      
        1 tcttttatta ttatgatgaa tcaagctttc tgtttttgtc acgtatgttg taatctttac
       61 gaaagagtag agttggctac tcataatcaa ccatacttcc catcatcgct aaatacgaaa
      121 taaatcagca ttcctacacc aatcaaagca caagctgcac caagaaaagg gatgacattc
      181 ccaaagttat ctgtattcat aagtatgcca ccacccacaa acaaaaagcc gccagcaatc
      241 aggtttttca ttttattcat ctcctttctt acgttatagt atttccttct ttcaatgagt
      301 attttgaaag ctatcttatt gtatgatgtt cttctaggcc tcttctttat tatacaggcc
      361 attttcgtta tctcatagaa atattccttt ttatctgaaa actattgtat accgtatgac
      421 atttttcttc atgaagttgt aagtatattc tcattcaaat gaaaatttca tcatagaaga
      481 gattgtattt ctaaattctt aagagtaaaa tacgaagtat aacttggatt tggaaggatg
      541 attggatgaa agctattacg cctgatatga caacaaaatt taacaaacag tttcaagcaa
      601 atatcaaaca gcaggcattg cagcgggcag ttgtgaagaa cggaattact gcttctgctg
      661 aaaatgtttc agcacatgtg gagaatacac cggtattttc tatagatttg gctacgggga
      721 aagtggctaa tcaaatgcaa tcggggcgtt gctggatgtt tgctgcactg aacacattcc
      781 gtcataagat gctgaatcaa ttccatttaa aagagtttga attatcacaa aattacactt
      841 ttttctggga taaatatgaa aaggcaaatt atttctatga aaacatcatt gcaacaggaa
      901 aagaggcaat cgatagccgg aaagtagctt tcttactcgc tactcctcaa caagatggcg
      961 gccaatggga tatgatcgtt tcattattcc aaaaatatgg cgttgtgcct aaatcggtga
     1021 tgccggaaag tgcgaatagt tcaaattctc gagatttgaa taactacttg aacaaattac
     1081 tgcgtaaaga tgcagtagtg ttacggaaaa tggttgctca aggagaaaca ttagacgcta
     1141 ttgaagaaaa gaaagaagaa atgctagaaa gcatttataa cttcttagct atctcattag
     1201 gaacacctcc aaaagaattc gattttgagt accgcgatga agaaaagaac tatcatcttg
     1261 accgaggact gacaccacaa attttttatg ataaatacat cggtgtaaaa ttagatgatt
     1321 atgttagcgt gatcaatgca ccaacaaaag acaaaccatt caatcgttct tatacagtag
     1381 agatgctagg aaatgtcgtt ggcgggaaag aagtcaaata tctgaatgtt gatatggaaa
     1441 ctttcaaaaa attagcgatt gctcagcttg aagaaggaga atctgtttgg tttggttgtg
     1501 atgtaggtca atcttctact agaactagtg gcatcatggc cttagatgct tattcaatgg
     1561 atgatctatt tgatacggat tttacaatga ctaaagctga acgtttagat tttggagaaa
     1621 gtctgatgac ccatgcgatg gtattgaccg gtgttgactt agtagacggg caatcaacaa
     1681 aatggaaagt cgaaaatagc tggggcgaaa aagttggaaa gaatggcttc tttgttatga
     1741 gtgatgcctg gatggacgaa tatacgtacc aaatcgttgt aagaaaagat ttattgacga
     1801 aagagcaatt aaatgcgttc aatgaagaac caattgttct atctccgtgg gatccaatgg
     1861 gtgctttagc atagacgagt atttcaatga agagtatgta gtaaagataa aaagagctgg
     1921 cttaagccag ctctttttat ctttaaagtc cattccctgt tttttatggt ccctgtgcta
     1981 taattctaaa taaaggataa ggattggaaa taatcctttt atcattaaaa atatgatgac
     2041 gaagtagaat aaaattggga gtagggggga aagtcatgga tatccaaact gttttatctg
     2101 atctgaaatt aaatggtaaa gtgattccag ttgttggtgg cgatgttaat cagacctatc
     2161 gtataaaaac cgaacatcgt gcttattttt taaaaatcca tccgaatgta aaaaaaggat
     2221 tttttgaagc agaagtagac ggattaaaag aactgtcagc attcgtacgt gtaccggata
     2281 cgtatatgct aggtgaaaca agtgaaggcg cttatttgtt aatggaatgg atcgagccgg
     2341 gaaaagggga tcaacgagat cttgctgcag ctttagctaa tctccatcag caaacagcgc
     2401 cacaatttgg ttttcgtaaa gataactatt tgggtacact tgttcagaaa aattcttttg
     2461 aagaagattg gtggactttt ttctttaaag atcggcttga atcccagatt tctttggcag
     2521 aagaaacgaa tcgatggaat gtacagcgtc aagaaaagta tctgcgattt aaagaacgtg
     2581 tattgaaatc ggttgaacca aaaaagatca ctccacgcct cttgcacgga gacctgtgga
     2641 gtggtaatgt gttctttgac cagcaagggc atccagtttt tgtcgaccca gctgtttctt
     2701 atgggaatcg ggaacaagat attgcaatga gccagttatt cggtggtttc cgaccggaat
     2761 ttttagatgc ttatcaaact atatttccat tagaaaaggg atggaaagac cgactgccga
     2821 tttaccagtt atattatctt ttggcacatt tgaatatgtt tggagaaagt tacggttccc
     2881 aagtagatca attactagaa aatttttaag aggagggcgt gtttttggca aaaaaatata
     2941 ccaaaaagca tgaagtttca tattatgagt gtgacatcaa ccaaacgatg acatttcctt
     3001 cgatgttagg agtagttatc aaaacgtctg aagatcaaag cgaccagttg ggaagaggca
     3061 gtgaattcgt caatagcttt ggacttactt gggtcatcac gaattattcc atggagatta
     3121 atcgtctccc tagagtcggt gaagtaatct cagtaacgac tcaagccatg gagtacaata
     3181 agtttttctg ttatcggaac ttctggatcc atgatgaaga tgggaaagaa ttagtcaaaa
     3241 tagaatctgt tttcgtattg atggattttg tgaatcgaaa aatgagcagt gttaatgaag
     3301 agatcattgc tccttttgag agtgagaaga tcaagaaaat caagcgtcag gaaaaaattg
     3361 aaaagattga ttcgggcttc atgttgccat atcgtgttcg tttttatgat atcgatagta
     3421 atcagcatgt taataatgcg atgtatttta attggatcat tgacgtatta ggatatgact
     3481 ttttgactac gcatgttcca gaaaaagtaa ttattcgatt tgataaagaa gtagagtacg
     3541 ggaatgagat cgaaagccat tttgaacaaa tccctatcga aaatggtgtc aaaacaaaac
     3601 atgaaatccg aatgcaagaa cagctgtatt gtgaagcaaa tattatatgg aaaaataaat
     3661 aaaaaagagg ttgtgacaga agggggcaac ttcaagaaat aagaagaaat ttacgaaaat
     3721 tgtttctcaa atttttgtaa attttcgact tagttttcga agaagctatt tttgtcacag
     3781 cctctctttt taagtttagc tattagataa tgatgtttag ttttggataa acgaaatcaa
     3841 ttcttcaccc gacaaaccat agtttacagc aatcaatagt tttaaacgtg ctttttgact
     3901 attaatactg ttacagaaaa taatccccat tttttctagt tcttttcccc cgccttcata
     3961 atcataaaca ggctctgcga ttccattgaa acaacgagaa acaagtacta cagggatttt
     4021 ttggacaaga agcttttcca aagcagctaa ggcttgtgga gggagattcc ccgcacctaa
     4081 agcttcgatt accaaaccgt ctactttcgt atgggcgatg gcttccaata agtccccttg
     4141 catcccagca tatgctttaa cgatcgggat agtcccatct acagcggaaa tgtccagtcg
     4201 ctttgtttct aaaagttcct gcaagaataa aattcgattc ttagttacta agccgatggg
     4261 acccaatgta ggtgttcgga aagtagcaac atttgtggta tgggtctttg tcacgtagcg
     4321 tgcagaatgg atctcatcgt tcatgaccac caaaaccccc ttatctagcg cttcttcaca
     4381 acttgcgaca cgaatcgcac tttcaaaatt ataaaggccg tcacttccaa gttcattact
     4441 tgaacgcatt gccccagtca aaacaattgg taatttgttg ccaatcgttg tatcaagaaa
     4501 aaaagcagtt tcttctaatg tatctgtacc gtgtgtgatc accactccgg atatacctga
     4561 tgcataagcg gacaagatac gttcttttaa taccaacatg tgagaaggca tgatgtgtgg
     4621 tgagggaaga ttgaagatat cttcaactaa taattctaca tgcttgggga ttgtgatttc
     4681 tgcatctaat aatgggtttg ccacatcagg actaacaccg cccgtgagca tgttttcttt
     4741 catggcgatc gttccgccgg tgtgtagtac aagtattttt ttcattttac agacttcctt
     4801 acgaataatt ttgcatagcc gttaaatctt attgtatact atataaaaga gttttgctat
     4861 cagtgaagaa taacgaatag cctaacttat cataaaaaag ctgaccttat taaaatggaa
     4921 aagactcaac cttgacctcc taatacaatg gagtatctgg ttgagtttct tttacaagaa
     4981 agcagccaag gaaatcaatc acgaaggtgg ccggaaatga tcagaatcgg attaacatcg
     5041 tttaaagaac atgacaaatt aactggtaaa aagaataaca ctctttatga atatgcaggg
     5101 tttctaccct tagtggaatt agatactgcc tattatggaa ttccccgaaa gtcctcagtt
     5161 gagaattgga taagtgaagt acctgaatca tttcgctttg tagtcaaagt ctatcaagga
     5221 atcagcggtc aaggagactg gaagccttat tatcagaccg aagaagagat gattgcgcat
     5281 tttttagatg ttatgtcgcc aatggtagat gctggaaaga tgttttgctt tttagtccaa
     5341 ttcccctcat cattcaaatg tacgaaagaa aatgtccagt acttgcgcaa acttagaaag
     5401 tggtttgagg gttatcctgt ttctatagaa ttgcgggatt attcttggta cagcgatgaa
     5461 tttcttgaac gtacaagaaa ctttatgtct agagccgctt tttctttagc catcatcgat
     5521 gagccacagt tgctgaatac aacgattcct tttgatccat ttgtcaccaa tccgaacttt
     5581 gctctttttc gattccatgg taggaatgcg caaggatggc aagcaaatga taaagagtgg
     5641 cgtaaaaaaa gaacgttata tcgttattca gaaaaagaac tgcaagaact agcacatgaa
     5701 gtcaaagtag ttgattctaa gacaaaagag gtaggtgtga tttttaataa taattctggt
     5761 ggtgatgcgg ctgaaaatgc attagcactg caaaaaatat taaatatcaa gccagatgga
     5821 ctcaatccaa cccaaatgga tctgttttaa gggcttattt tattcaagaa aggggcgaag
     5881 tctatgatca aagctatttt ttttgatatt gacggaacat tggtcaccaa tcgttcaaaa
     5941 gcgttggaat caacaaaaca agcaattgaa tatgctcgga aaaacggcat tttatgcggt
     6001 gtagcaacgg ggcgcagccc agtaaagatc aaagaaatca ttgatgaatt ggaattagat
     6061 atgtatgtcg tgtataatgg tcaactggtt tttactgcag atcgcacgat tatcgaccac
     6121 ccttttgaac aaaaagtatt ggaacatatt gttgaatttg cagatgagaa ccatcgacaa
     6181 atcgtttttg gtgcgagaaa tcggttagat ggatcaacga cgatgctatt aggacaatcg
     6241 atttttatca agcgactagt cagcttttta ccgcgtaaat tcccggtacg tctgatgaaa
     6301 aaaatcctcc aggtttttag ccctcaccga caaaaggatc gttatgaaac gttagagata
     6361 ttaaaagaac caatttatca atgtatattg ctcagtccgg agtcagaaca gaaaaagtta
     6421 gaacatcgct ttcccgagtg tacgtttcag cgttcaaata cgtatactgt agatatcatc
     6481 ccaaaaggtg gttcaaaatt actaggcatc caagctttcg caaatgctgt cgaaattgaa
     6541 atggaagaaa ttatggcatt cggcgatcat tacaatgata tcgagatgct gaaaggtgta
     6601 ggaattggag tggccatggg gaatgctcag atcgaagtaa aacatgctgc agactttgtg
     6661 actcaatcaa atgaagaaga tgggatatac gaaggactga aacacttcgg tctgatttat
     6721 tagtcaatga aagaaggaaa aaatcagtat ggaagcagag acaccttttc aaaaagtaga
     6781 aacattccac aaaacttttg atccaagaag accagagata cccacggctt ttacagaaaa
     6841 tgaagctcat acacgtgctg cgttcaaaat agaagaactt gttgaatttg ttgcagctac
     6901 ttcacctaat aaagaacaac tgcatgaagc tgttatgctg ctgcacgaag cattagataa
     6961 agcagaagaa aaaatacttg gtaaaacaca gtggggaagt gatccgctgg ttgaacaagt
     7021 agatgcactg acagatatcc tttactttac ttatggttct ttttcattac taggaatagt
     7081 gcctgatcga atattcgaaa tcgtccatca ggcaaatatg gggaaattat ttccagatgg
     7141 aaaacctcat tatgaccctg taacaaataa agtgttgaaa cctgaaaact ggcagatgga
     7201 atatgctcca gaacctaaaa tcgcggcaga aatccaacgt cagattcaag aagcgattgc
     7261 taagaagaaa tccgctgata taggcatgtg cacaaatgaa aaagagtgat cagagtttca
     7321 ctatttttgt tatctttata cgatggaaaa acaaaagatt ttcgtttaag ttagtgaatg
     7381 catgaaaata gtatgctata atctagaata gatgtctttt gcacgagaga cgtattattt
     7441 ggatttatgc caagcagaac gccatctgtt gcataaaaga tgcatactga aaacggagga
     7501 accataaatg ggaaataatg ttatcatcgg aatcgtcatt gcaatcatta tagtcgccat
     7561 tgtcgtcttt ttggttagtt acttgatgaa gaaaaaaaac caagatcgat tggatgcctt
     7621 agaaaaacgc aaggaagaat tatttgactt gccagtgatt gaagaagtcg atgatgttaa
     7681 aaaaatgcat ctggttgggc aaagccaaaa tacctttcgt gaatggagtc aaaaatggaa
     7741 tgacatatct acttcctcgt tcgctgaact agaaagtcaa attttcgaag tggaaaacct
     7801 caatgaaagt tttcggttct taaaaggaaa aaaagcagtt gttgaagcag aagctacaat
     7861 ggaccaaatg gagaaacaag tgacggaaat ccgtgaaggt ctaaaggaat tgcgggaaac
     7921 ggaagaacgc aactcactag ctgttcagca ggcacttgac gtctatgaag aactgaaaga
     7981 aaaagtcaga gaagacgagc atgaatacgg accagctctt tttgaattgc aaaaacagat
     8041 caaagtgatc gaaaaagaat ttacgcagtt tgtgacttta aacacttctg gagaccctgt
     8101 tgaagcccgc gaggttttgg ataaagcaga aaaacatacg tatgaagtgg aagctctgat
     8161 gaaaaaaatt ccaccgctgt atgaggagct ccataccact ttccctgaac aacttgaaga
     8221 aatcagtgat acttacgaga aattgatgga agaacaatat gtattcccag aagaagatct
     8281 tgctgaagat atcgcaaaag taagtcgaag aattgaaaat tcattagcca atcttgaaaa
     8341 aacagaagtt gaaacggtcg aatttgaaaa ccgtgaaaca gctgatttga ttgattcgtt
     8401 atatgatatc ttagaacggg aaatggaagc tcagagatat gtaaaaacta accaatcaac
     8461 gattgcagag tatatcaaac atacaacaaa gaataaccgt caattattga ttgagctgga
     8521 tcacacatct caaagctata cattgaacca caatgaaatt ggccgtgtac gaggtttcca
     8581 aaccgaagtg gaagaaatgg aacgtcaaaa tgaacagatg attccacaga tccgtcaaca
     8641 cgaaattcct tattcagaag tgcgcacgtt ctataaaaca gtcttcaaag tcttagaaga
     8701 tatcgaaaag caacaagtag agatcgacga ctcattacat gaattgagaa aaggcgaaaa
     8761 agaagcgcaa gaaaagatcg atacattcga attcaaattg cgcagtttga aacgttttgt
     8821 agaaaaacaa cgtttgcctg gcttgccgaa tgattaccta gaattctttt ttgttgctac
     8881 tgaccgtatt gaagaactaa gtgttgtctt gaataaaatt cgagtaaaca tggaagaggt
     8941 caatcgttta gttgctctat gtgaagaaga tctagaatta ttagataaga agacacatga
     9001 tttagtagat gcagcagcat taacggagca aatgctccaa tatgcaaatc gttatcgtca
     9061 tacacacgaa gaagtgagag aagcaattga taaaagctac tatttattca ataaagaata
     9121 tcactatcaa gaagcattag acgaaatcgg tacagcatta gagcgagtag aacctggtgc
     9181 tttcaaacgc atcgaagatt tttattttaa tcatccagac ttagtataaa gcaaaaaagt
     9241 tagtaaacca gcaagagcaa gacggattat tgtcttgttc ttgtcttttt ttgtatattt
     9301 gaaaattgaa acaagtgaaa atttcacctg ctcttgaaag caccttggac aaccgttata
     9361 atagaaaaga atttcaaaaa agaggggttt cttatgatat attttgataa cagtgcaaca
     9421 accccaatct ttccgcaaag cttagatgca tatgtaaaaa ccagtcagcg gattattggg
     9481 aatccatcaa gcttgcatga tttaggcaat caagctaacc ggttgttgca gcaagcaaga
     9541 aagcagatcg ctgatttgat ccatgtagaa ccagaagaaa tctattttac ttcaggcgga
     9601 acagaaggag ataactgggt attaaaagga acgatgatcg aaaaaagaga atatgggaat
     9661 catatgatca tttcaggagt cgaacatccg gccgtcagcg agacagcaga acaattaaaa
     9721 gaattaggaa tcgaagtaag tatcgcccca gtggataaac gcggatttgt acgtgtcgac
     9781 gaattgaaag aattaataag aaaagagaca gtattagtct ctgttatggc tgtgaataat
     9841 gaagtaggat cgattcagcc catccaggaa atcagtgatc ttttggatga ttttcctaaa
     9901 attcatttcc atgtagatgc tgttcaggcg attggaaaag taccattctc gcaatggttg
     9961 acagaaagag ttgattttgc aacattttca gctcataaat tccatggccc acggggaact
    10021 ggtttcattt attggaaaaa gggtcgtcgt ttagcaccat tactgacagg tggagggcaa
    10081 gaaagaaatc agcgaagtgg gacagaaaat gttccaggta ttgtggctat ggttaaagct
    10141 ttacgtttat cattagagat aaaggaacaa aaacctgagc agacacaacg cttaaaagta
    10201 gctctaatca atgcgttgaa gacgtatgag aaagtgacga ttttttcaga aggaactgac
    10261 tatgcaccgc atattttatg ttttgctcta aaaggaattc gcggcgaagt tctcgtccat
    10321 gccttagaag aaaaacaaat atttgtttct actactagtg cctgctcctc acgtaaacat
    10381 atggcaagca gtacattgca cgcaatgcat gtaccaaatg atctggctac atctgctgtt
    10441 cgaatcagct tagatgaaaa caattcgctt gcagaagtcg agcaatttat gattattttc
    10501 aagcagcttt ataagaaatt ttctgcaatc aattaaaaga ggagtgttct tgtgaaatac
    10561 agtgaaatta tggtccgtta tggggaactt tcgacaaaag gaaagaatcg aaaaagcttt
    10621 atcatgcaac tagcacaaaa tgtcagacaa gctttgaaag actttccaga aatcaaaatc
    10681 catgctgatc gggaccggat gcatctttta ttgaatggcg cagacgggca gctagttatt
    10741 ccaaaactag caaaaatatt tgggatccaa aatttctctc caagtattcg tgtagaaaaa
    10801 gatgtcgaag ttttgaaaca agctgttcaa gacatcatga aagaaattta tactgggaaa
    10861 gaaacattta aaattatcgc taaaagaagc gatcaccaat ttgaattgac aagtaatgaa
    10921 ttgaatcaaa cattaggtaa tgctgttttt gatattttcc cgcatatcca agttcaaatg
    10981 cgtcaaccag atattccatt acgtgtagag attcggcgtg atggcgctta tctatcgtat
    11041 gaaacgatca agggagctgg aggattgccc gtaggaacaa gcggaaaagg aatgcttatg
    11101 ctttctgggg ggattgattc tcctgtagca gggtactttg ccatgaagcg gggagtggaa
    11161 attgaagctg ttcattttgc tagtccgccg tatacaagtg aacaagcact gcaaaaagca
    11221 aaagatctaa cagccaaact agcaccttat gtgggaacga tccattttat cgaagtgcca
    11281 tttaccgaga ttcaagaaga aatcaaaaag tcagtgccac aaggatattg gatgacaatt
    11341 actcgtcgaa tgatgttgcg tttgaccgat gaaattcgcc gtattcgtca tggtttagtc
    11401 attttgaatg gtgaatcatt aggtcaagtg gcttcacaaa ctttgcaaag tatggtggct
    11461 atcaatgaag taacgaatac gccaatcatt cggcctgtag cgacaatgga taaacttgaa
    11521 atcattgaag tagcagaaca gatcgataca tttaatcttt ctatccagcc ttttgaagat
    11581 tgctgtacga tttttgctcc tccacagcca aaaacacgcc ctcaactgga aaaggtccat
    11641 caatatgaag agcgtttagc aatagatgaa atgatccaac gagcactagc tggcttgaag
    11701 atggaagaga tacaagcaga atcgtctaat gaaaaaactg aagaattttc agaattgcta
    11761 taagaggtta tgaaaatagt gttttgacca gagtattaga gaaacaaaac gaaaaaatag
    11821 ctccatgtat tttaccgttt ttgaactaat gtcgaagatt agctgattga ataccattta
    11881 tcaagaagtt atggaaaagc cggttctttt ttactaactg aaaaataaaa ttttatttag
    11941 agatcaagct acagttgata aatgatataa aaaagagaat ttcccatgaa atagcgaggt
    12001 tgtgacagaa gtgggcagct tcaagaaata agaaggaatt tacgaaaatt gcttttcaaa
    12061 tttttgtgaa atttcggctt atttttcgaa gaagttactt ctggaacacc gtgtatcaga
    12121 ggttg
//
LOCUS       DAZUJR010000085        11646 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.085, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000085 DAZUJR010000000
VERSION     DAZUJR010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11646
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.085"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..2564)
                     /locus_tag="ACG804_002330"
     CDS             complement(<1..2564)
                     /locus_tag="ACG804_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HFS4833245.1"
                     /translation="MNQYVKKLIASILFVFPLLMVTSVFADVEKTSESTQSENQSFDK
                     TTFSEESITSETTESQSEAPTSNTRQEENKTSETSEVAEQTSDSSEEVQVRVVSADGY
                     SEAATTEELTQLLADESVAKIRLTQPLTLDRELEIKRDIVIDFGGLAHNFGTHHIYIN
                     ETPQSIEFQNFKGTAAHPGGLIPNIDGNAIIIAYMSDFWGNRYHFTGEIKFTGTLDLY
                     DGSKLGLIYAPRATVTLDGVSGVLDVQPVKEGMNAAPGKAYFCRSYQLNVINGSQLYG
                     PYLGKFYGFLDSGDETGSGKTAPGLHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVT
                     FKVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSRVAVSNDGKITINTATTGGFRLQG
                     DSSQIHVSSGGQISVKMAGDGDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSA
                     VRFENGTQKLTVTNGGSLKVRNAGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFT
                     VTGEKSNIDIRADSGATVDTTGDIDLNFMAGEKTYLVMVGKTGEDKTGIISGDVLNVD
                     LESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKAGVTFDNFEKDP
                     DYFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRV
                     PTNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSPVEITALTQGQTDE
                     NEGTGYNPWGEGEQGGLFEVQVPNEERLTTGDQVQIVAAKKVRGGQEVTELDSAKTTV
                     DVIPPEPAKLSTTLINAASRSITGTGEAGALVSLKKNQAVLSETTIDDTGKFVLSIP"
     gene            complement(2786..3670)
                     /locus_tag="ACG804_002331"
     CDS             complement(2786..3670)
                     /locus_tag="ACG804_002331"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFS4833246.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPEAINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSILLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(3765..4202)
                     /locus_tag="ACG804_002332"
     CDS             complement(3765..4202)
                     /locus_tag="ACG804_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833247.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWVFYLVKK"
     gene            complement(4419..5330)
                     /locus_tag="ACG804_002333"
     CDS             complement(4419..5330)
                     /locus_tag="ACG804_002333"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFS4833248.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(5707..6345)
                     /locus_tag="ACG804_002334"
     CDS             complement(5707..6345)
                     /locus_tag="ACG804_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4833249.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDFVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFNQETKHLTGREKRLIKRNALSFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKEQVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(6349..8331)
                     /locus_tag="ACG804_002335"
                     /pseudo
     CDS             complement(6349..8331)
                     /locus_tag="ACG804_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
     gene            8511..9176
                     /locus_tag="ACG804_002336"
     CDS             8511..9176
                     /locus_tag="ACG804_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4833250.1"
                     /translation="MNIGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHQTLGLPIDFPSIESATESIEPTLPDEPLVIKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETVDRFNPFLKPQIGYTTLPVGYVENSIEHWVCNDIFVHGTW
                     LSFHAGEVEKGKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILIQDYDDALKRSPQEP
                     DRH"
     gene            complement(9573..11606)
                     /gene="brxL"
                     /locus_tag="ACG804_002337"
     CDS             complement(9573..11606)
                     /gene="brxL"
                     /locus_tag="ACG804_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protease Lon-related BREX system protein BrxL"
                     /protein_id="HFS4833251.1"
                     /translation="MEQQEILKLSEFFPGKIVRKDLTKKIKEGANVPVYVLEYLLGMY
                     ASSLDETLVEKGVENVKNILARNYVRPDEAEKVKAKIRELGGYTVIDKVTVHLNEKKD
                     CYEAEFSNLGLKNVQISEEYPKKFDRLLGGGIWCIVSMEYWYDENDRWNSPFIAKKVD
                     PIQMPGLDIEAYKMARKEFTTNEWIDLLLRSIGMEPTQFNKRVKWLHLARLIPLIENN
                     FNLCELGPRGTGKSHVYKEISPNSILVSGGQTTVANLFYNMASRTMGLVGMWDCVAFD
                     EVAGIKFKDNDGVQIMKDYMASGSFARGKEEKNASASMAFVGNINQSVDVILKTSNLF
                     EPFPEVMGTDSAFLDRMHCYLPGWEIPKYRPDFFTNDYGFITDYFSEVMRELRKVSFG
                     DSFDKYFKLGSQLNQRDTIAVRRIVSGMMKLLYPDGRFEKSDVEEILRFALEMRRRVK
                     EQLKKIGGMEFYDVNFSYIDLEEEREEYVSVPEQGGGTLIPEGLGKPGHLYTVSYGKT
                     GQLGTYKLETQMTSGNGKFERTGINSDAGAREAMDSAYRYLRANYGSVSQSISLTTKD
                     FVVHVQDMNGIGMTKTLSLSTIIALCSVSLNKPVLPSLVILGDITIGGSMIKVDNLAN
                     CLQVAKDAGAKKVLVPMISAADIGTVPPELMGTFNLIFYQTPEDAVFKALGVE"
BASE COUNT         3564 a         2385 c         1808 g         3889 t
ORIGIN      
        1 gggatagaaa gaacaaattt acctgtatca tcaatagttg tttcggacaa aacagcttga
       61 ttttttttca atgaaaccaa agctcctgct tcgcctgtac ctgtgattga gcgagaagct
      121 gcattgatca atgtggtact taatttagca ggctcaggag gaatcacatc gactgtcgtt
      181 ttggcagagt ccagttctgt cacttcttgg ccgcctctta cttttttagc agcaactatt
      241 tgcacttgat cccccgttgt tagtctttct tcgttgggta cttgaacctc aaacaaaccg
      301 ccttgttcgc cttctcccca cggattatat cctgtccctt cattttcatc tgtttgtcct
      361 tgtgtgagag cagtaatttc tacaggtgat ttcgtcgtat ctgcataagt aatacgtaaa
      421 gtcacttcta cttcgcctgt ccaagcatct cttggctttg cctcgacacc ttcgggaaca
      481 acgacatgcc catagatttt tttatctgca ttcgttggta ctcttaagga ttcaatcatc
      541 ggaagctggt tattggcact gattcgatta taatttttca ttccggcacc tgtctgagca
      601 aattcatttg ttaaacctgc actagggctt gatacaaaat tacctaagtc ggttccattg
      661 atcgataagt ctgtcatatc agaaaaataa tccggatctt tttcaaagtt atcgaacgtt
      721 actcctgcct ttcgccataa agcaatttct gaatgagcga tcttcaaaga agaatcgcca
      781 tttccttgaa atacccagcc acctatgcca ttagtctcgc ttccgatccg tttgttttgg
      841 aaatcgaaat aggtaggaga ttctaagtct acattcaaca catccccact gatgatgcca
      901 gtcttatctt ccccagtttt cccgaccatg actaaataag ttttttcgcc agccataaag
      961 ttcaaatcaa tatctccagt tgtatctacg gtagctccgg aatctgcgcg tatatcgata
     1021 tttgattttt ctccagtaac cgtaaaatca gctgaccctg gactttctag aaaaccagaa
     1081 gcgtcataaa attggatcgc ttggtttcct tgattgagtc tgttcacata agatttgcca
     1141 tcccctgcat ttcttacctt caatgagcct ccattagtta ctgttagttt ttgcgtaccg
     1201 ttctcaaaac gaactgcgct agaacgacca ctttgcttat caatatcgat gactgatccg
     1261 gctccttcta cgatcaaaga aagtcctttc cctacaaaac gcatcccatt gtttccaggt
     1321 tggtcgccat ctccagccat tttgaccgag atttgtccac cacttgatac atggatttga
     1381 ctagaatctc cttgcaggcg aaatccgcca gtagtcgctg tattgattgt gattttccca
     1441 tcattcgaca cagcgactct tgatcctgag cctctcattt ggataattcc gcgattgttg
     1501 tcgttggtaa tattgatctt tgtatttacc gaaaattcac ttcctgagcc actgacttta
     1561 aatgtgacat tcccgggtag cgtatcgaca gcctctcctt catcgctgac gccatctgcc
     1621 cgatcatagt caagagagac ctttgaacca ctcaagatat ggagtcctgg tgctgttttt
     1681 ccactgcccg tctcatcacc tgaatctaga aaaccataga attttcctag atatggtcca
     1741 taaagctgac taccattgat tacatttagc tgatagcttc tacaaaaata agctttaccc
     1801 ggagcggcat tcatcccttc tttcactggt tggacatcca atacaccgga aacaccatct
     1861 aatgtgacag ttgcacgagg ggcgtaaatc aggcctaatt tagaaccatc atataagtca
     1921 agtgtcccgg taaattttat ttctcccgta aaatgatatc tgtttcccca aaaatcggac
     1981 atataagcaa tgataatggc atttccatcg atatttggta tcaacccacc tggatgagct
     2041 gccgttcctt taaaattctg aaactcgatc gactgaggtg tctcattgat atagatgtga
     2101 tgtgtgccga aattatgagc aagtccgcca aaatcgataa cgatatctcg cttgatctcc
     2161 aattccctgt ctaaagtcaa aggctgagtt aaacgaatct tagctactga ttcgtctgcg
     2221 agaagctgcg tcagttcttc tgttgtggca gcttcgctgt acccatccgc tgaaacaact
     2281 ctaacctgta cctcttcact gctatcagac gtttgttcag ctacttctga ggtctcactt
     2341 gtcttatttt cttcttgcct tgtattagaa gtaggcgcct cactttggga ttctgtagtt
     2401 tcagaagtaa ttgattcttc tgaaaaagta gtcttgtcaa aactttgatt ctctgattgc
     2461 gttgattcgc ttgttttctc tacatcggca aaaacggatg tcaccatcaa gagagggaag
     2521 acaaacaaaa tcgacgcaat cagctttttt acatattgat tcattctcca ccatcctctc
     2581 tgacgttttg acaattttat tttaacgttt taatttattt gtaattgtac tttcatattt
     2641 aaaatatgta tttttatggc aaatttttct gttaggtgaa aatttctttt ttgtacaaaa
     2701 aaaggctgtg acaaaagtct tgtcacagtc ccttattccg aacaaccgat gtcctcctga
     2761 caactcttcg gtcacaacct ccattttaac aataaacctg taaatgtgag ggtaacactt
     2821 tgattgtcac aggtaattta tccccttcat ctccatcaac attcgtcgtc aattcttcct
     2881 catcagctaa tgacacaact aattgctcac aagtaagata ggctagattt ttcgtagatt
     2941 catctactcc ttttaatagg tctggcaatg ttttaagcgt atcgatcaaa gaagaatctt
     3001 ttaaataaac caaatggagc ttaccatcat ccacttttgc atttggaagt aatgtttcaa
     3061 aaccgcctac tgagttagtt agtcctatca gcaagatact gctctcaatt tcttccttct
     3121 ttccatcaac ttctacgtga aacgagtagg attgtgtgga agctaactgt ttgattcctg
     3181 acatgaaata agctagtttt ccaaatttcg tcttcttctc cgcatctaca tcattgattg
     3241 cttcagggat agagccaatt gcgacgacat tcataaaata gtcgtcattt atttttccaa
     3301 tatccaatgg cttgactgat tcaatcgaaa aatgattgat cgcttcctca ggttctagcg
     3361 gtatccctaa tgctcgagcc aagtcattca ccgtacccaa tgggaaaaat ccgaaatttg
     3421 gccgatgttc ttgttcagcg attccactga ttccttcgtt gactgttcca tctccgccca
     3481 tgacaaacac actatgatac ccttccgtag ccgcttcgcg agtaaagttt tttgcatccc
     3541 ctgctttttt tgtatgcaag acgaccactt catcaaacac cgattccaat tttgctatcg
     3601 ctaattgctc aaattccttt gcttgttcac cgcctgaact ggggtttacc actaataaaa
     3661 cttttttcat cactttcttt cccttctgat tgatttcttt aatataacga tagcataaag
     3721 aaaaaaatta ggctgtgatg aagtactgtt catgaaacat tcatttattt tttgacaaga
     3781 taaaataccc atactatgaa actgaggaaa attaaaacaa tgatatagga aataaaagaa
     3841 aatgataggc attgtatacc taataaagta aaaatcttag gtggcagata aaaacacaaa
     3901 aatagcaaga gaatgtaata gcgtttcttc cactttttgt tatcagacct tatagcgatc
     3961 agaggaatac caaatgcata actgaaaaac tcttgatgta ctgttaatat gtcacgacct
     4021 tgaataataa atgcaacaat ccccgctata attagtgtgc ctaataccaa aacggaaaat
     4081 tgatgaatat attttatata caaatgatcc attgtacttc ctgccttttt atttgtgaga
     4141 aaaacaaatc cgtatacgtg aataacttct agaaataaaa gaaatttgca aaaccactcc
     4201 atttatctac ttctacgtgc attttttaat atcgttttct ttatttaaga ttatacagaa
     4261 aaatatctag ggtggctgga ttctaagtaa aaaaaatttt taaaataaaa agaactaaat
     4321 caagtaataa ttaaactact gttgatttag ttctaataaa aagatttaga tgaacagttt
     4381 tattgattta aatagttcat attttttatt tataccgctt atttactact tgctgtacta
     4441 gaatctgaag tgaatgtact caaaacattt tcaaagtctt tgtctttgat ttttacatta
     4501 gcgtctttca atacttcgcc aattacttta ttctggaagg tactgtcact taattttgtg
     4561 tctgttgcaa tttctttcaa ttcttttttg tatttatcca tgtcgttgcc tttgttttgg
     4621 tttttcacca ttttaaccac ataatattcc gtagtataag ttgaagcatt ggtagaagtg
     4681 atcacatcag aaacttgacc atctttcaac ttaaaggctg cttctttgac ttctgccgga
     4741 accgttgtag tagtggaatc aaatttcact tttccgccat cttcttttgt cgtagtatca
     4801 gttgacttgt ctttggctaa tttagagaaa tcgtctccct tatcagcagc tttcttcaca
     4861 tcttttgcat catcttcact tgctacttgg ataatttgag cttccacttc tggatggaaa
     4921 gattcccaag ccgtttttaa atcttcatcg gtcaatttga tatgtttctt tagaccttct
     4981 tgaaaggcta gactttgttt gatactgtct ttgaatgttt gttctgtgta acctgcagat
     5041 ttcaattgtg aatcaaatga atcacccaat tgtttctttg tttgatcata ttgggaatcg
     5101 atttctttgg ttgatacgtc atctccatat ttatcttcaa atacttgata aacgatcaac
     5161 tgttgcacag cggaatctgc tccttgcatt tttttcaagc tatccattac ttcttgttcg
     5221 ctgattgtac cgcctttata actaacggct gttttttcac cggcattcgt acagcctgac
     5281 aataagccag tgcctagtac gatggcaagt gctaaaaatc tttttttcat ttatcaattc
     5341 tcctactttt cgttttttgc gaattgctaa aaacaaaggt gttcaagatg aaaatcatca
     5401 agaacacctt tactaatctg ctcgatacgt cctgaataga tataaggcta cacaatccag
     5461 aaagttcgct cagcagaata aatgtcaagt agcacatcac accttaatat actacttctt
     5521 ttgttaccgt ttttcaagtc tatcttgcgt tccgtattta acgtaactaa ttcttagaac
     5581 aaatgttatc gattttgttt ttcttcttcc gctgttggga tattcaaatc agacactttt
     5641 atgttcgatt ttccagacat ttttttgttg tttttattag aaaaagtttg ttttttcatt
     5701 tgttttctaa agcatgatct tcttgtttcc tattttggtc agatatggat catgcgtgac
     5761 cacgataact aacgtacctt gggaagcctg ttgcgataag atttcaacga cttgctcctt
     5821 atttcgttta tctaatgatc cagttggttc atcggctaaa atgattttgc tattcttcaa
     5881 taagactctc gcacaggcga ttctttgctt ctcaccacca gataatgtgt agataggcgt
     5941 acttagcttc ttgtttatat ttactttttt caatgcctca tactttgctg ttcgcttatc
     6001 tgaaacattt aaattcgaaa acttcaatcc aatatctaaa ttaaaatcga ttgtttcata
     6061 ttcaatcaac ccaaaatctt gaaaaagaaa agagagggca tttcttttta tcaagcgctt
     6121 ctctcttcca gttaaatgtt ttgtttcttg attaaataaa taaaattgcc ctgaactgaa
     6181 ttgatcattc aatcctaata tattcaataa agtacttttc cctgctccgc tctctccaac
     6241 tacagtcaca aaatccccag catccgcagt gaaacgatcc aaatgaagaa tcgttttgtt
     6301 tcgaatgatt tttttcgcac cttttatcac tatcaacggc tccaattgtt aacctccatt
     6361 catcagcaat aactgacttt tcttttctgt agacaaaata aaaacaactg aaagaataaa
     6421 atcaatgaag ctaaagaaaa aaatattaaa aagatattta ggctctcttt ctataagaaa
     6481 aaggaagatt acacttgtcg ttccccattt gatgaggttc atcatgaaga aatctttata
     6541 cgtttcaaag agcgaataac cacttgaacg aaagatagcg attttccgac aattgtagac
     6601 aaaatatatg cataacatga catagctcaa caagaagaaa gaaaagaaag tgagtaaaaa
     6661 tatctgtatc aagtaatgaa atgatctgct taacactttg acagctatct cttcagtctg
     6721 agtatacgga aatgataact gcaagttatc acgtaactga ctttcttcaa tcagctcaaa
     6781 taacctttct ttcgacaaag agcctatctt gatctttaac ggtggataga tttctccgct
     6841 gagaatattt ctttcccaat acgtactgtt tttcaatgtc agtatttcaa caaccggata
     6901 atgttcgatc caggggatag aaggaataaa tgtataaatg ggttgattgt tttttataaa
     6961 tagaaatttc ggttcttttt cactgatttc ttgataatat tctgttattt gcgccaggtc
     7021 attttttaaa tctgtatgtc tatatcgttc agggatcaat ataacagggt gcgtttcttt
     7081 ttcggttatt tggatcaacc ttccagagac atcaatcaaa ggaaatttct taagataatt
     7141 cagatttatt tttatccctc tgccaaactg ttcattttct tcattcaagt aatctgatac
     7201 attgactaat atacttccgt ttttattcaa agtttcatat aattcctgat cggctgctga
     7261 tgcaaaacga ttggaataaa taaaatccac gtggtttttc ccgatggtta ctggataaaa
     7321 tacatgatag tcctcaccag cgatttcttt tggtgtttca tgggaaacag ctaactgtga
     7381 agaagaaaaa acgatagttg ctaattcgac attggcaacg gtcaaaagaa gagaaaacaa
     7441 caatccaaat gtaaaaagaa tgtattggat atagttgaac gcttctctta acgaagcgat
     7501 tttttcaact aataaaagag aaatcaaaga gataccctat attccgctga acaagaaaac
     7561 gtacatctgg aacaaataaa gaaattgctc cttataatac ataaaaataa aaccaccaat
     7621 gattcctgca attatgaatg taataatgat tttctttttc cccaataaac accacaatac
     7681 ttgatgtaat gaaaagccat tattcaacaa taaactgatt tctttattca tcaataagaa
     7741 aaaggatgat aacaaaagga ataaaagaat caatccaata gttaaataca ctcgataatt
     7801 atatacgtct gtacttgaaa taaccgaata cgaatagcta ttttcaaagt cttcaaaaat
     7861 attagtggca taatcagtgt gaaatgcttg attgaatcgt tccacaaata gtaaaatgaa
     7921 ccgttcatag gcttcttttt ctctcgtcat caagaaaaat tcaccttcaa aatcttttat
     7981 tttgatcgat tcttcaatgg acgttacgcg aaaggaggta ttagaatagg gtaccttctc
     8041 gtgagaagat ttgacatccc cttgataata caatgtcatt tcaagctttg gctgtatctt
     8101 gaagttccaa gatgtatcta cttcattgga ttcatttact gtttttttca tataagaaag
     8161 ctcagtttct gatgagacat tttcaaatac catgattagc tgctcatatt cttcttgccc
     8221 aataaaatgt tgtggcaatc gaatcggagt ataagtatct gtttgatgga aaaattcatt
     8281 tgtccgatag agtacctgtt tatttataat aaccaaggca aaaccactca tgataccggt
     8341 cactatgatt gtgagtaaaa ctgtgaactt ttttttgatt atcaccactc tcccttactt
     8401 aaatgattct ttgataaaat cataccgttt ttcatcaaaa aaacgtatct atcaaatgta
     8461 taggtcatgt agaataaatc tatatactgt agaatcgaaa ggagaagaag atgaacatcg
     8521 gagaaaaaat acgaacttac cgcagaaatt gtaagcttac gcaaaaagaa ttaggcgaaa
     8581 aaatcggtgt ttccgataaa acaatctcta gttgggaaaa ttctcgtaca atgccagacc
     8641 ttgaaatgct gtcactttta catcagactt taggtctgcc gattgatttt ccttctattg
     8701 aatcagctac cgaatcaata gaaccaacat tgccggatga acctcttgtt atcaagaaat
     8761 cttattcatc aaaacaaccc ttctcactca aaaagacact atctttcttt ctgctcgtct
     8821 tttgtttggt ctatcttttt cttatcaatt atcaatataa aaatgaaacg gttgatcgat
     8881 tcaatccttt tttgaaacca caaatcggct ataccacact ccctgtagga tacgtggaaa
     8941 attccatcga acattgggta tgtaatgata tctttgttca tggtacatgg ctgtcttttc
     9001 acgctggaga ggtagaaaaa ggtaagaatc atgctgtaat caaacacaaa ggaaaacacg
     9061 tcatgaacgt tcgcctgctc acttgggaag ccattccctc agattaccaa gaaatcctca
     9121 tccaagacta tgacgatgcc ttaaaaagaa gccctcagga gccagatagg cattaagtag
     9181 gagatgaacg tagagataga aaaaatcaat gcacatgatc ttatcaaaaa aaaacagggg
     9241 tacaaattaa ttgaaaaagc tttgagatga aagttcctaa ataaaaaagt tcagaatgat
     9301 aggtaaaaaa atgactaact attctagtat taggctattt gtattattct tctgttattt
     9361 ttatatcaaa aaatccagaa ataactaaat ataggtattt ctggcttata gtataatatt
     9421 tacgccacag cccccaatga ttctttttgg aatcatgatc aaggacggac atacacaaaa
     9481 atattttgcc cattcgatcc gaatagatta acgactaatc tagtaagtaa tatagattgg
     9541 tacgtagtca aaccagcaaa tggaaaagtt gtctattcca ccccaagggc tttaaagaca
     9601 gcatcttccg gcgtttgata aaaaatcaaa ttaaaggtac ccattaattc tgggggtaca
     9661 gttccaatat cagcagcgct tatcataggt acaagtactt ttttcgctcc ggcatctttt
     9721 gctacttgta aacagttagc taaattatct accttaatca tagaaccacc aattgtaata
     9781 tcccctaaaa taactaaact tggtaataca ggtttattta aggaaactga gcataaagct
     9841 attatagttg ataacgataa tgtttttgtc ataccaatgc cattcatatc ttgaacatga
     9901 acgacaaaat cttttgtcgt caaactaata gactgactaa cacttccata attagctctt
     9961 aaatatcggt atgccgaatc catcgcttct cttgctccag catctgaatt gatcccagta
    10021 cgttcaaact ttccatttcc cgaagtcatt tgcgtttcca atttataggt acctaattgc
    10081 ccagttttgc cataagatac cgtgtacaaa tgccctggct tccctaaccc ttctggaatc
    10141 aaagttcctc caccttgttc aggaacagaa acatactctt ctcgctcttc ttctaaatca
    10201 atgtatgaaa aattgacatc ataaaattcc attccaccaa ttttctttaa ttgttctttt
    10261 acacgacgac gcatttcaag agcaaatctt agtatttctt cgacatcact tttttcaaat
    10321 ctaccatcag gatacaacag tttcatcatc ccagatacaa tccgacgaac tgcaatcgta
    10381 tcccgctgat ttaattgaga accaagtttg aaatatttat caaaactatc gccaaaacta
    10441 acttttcgaa gctcacgcat gacttcagaa aaataatctg taatgaagcc atagtcattt
    10501 gtaaaaaaat ctggtcgata tttaggaatt tcccaacctg gtaaataaca atgcatccga
    10561 tccaaaaagg ctgaatccgt ccccataacc tccggaaatg gctcaaataa attcgaagtt
    10621 ttcaatatta catcaacgct ttgattaata tttcctacaa aagccattga tgctgaagca
    10681 ttcttttctt ctttgcctct agcaaaagat cctgaagcca tgtaatcttt catgatttga
    10741 acgccatcat tatccttaaa tttaatccca gcaacttcgt caaaagcaac acagtcccac
    10801 atacctacaa gtcccattgt acgactagcc atattataga aaaggtttgc tactgttgtt
    10861 tgtccacctg aaacaaggat tgagtttggt gaaatttctt tatatacatg cgatttacct
    10921 gtaccacgtg gtcctagttc acagagatta aaattatttt caattaatgg aataagtctt
    10981 gctaaatgaa gccattttac ccttttatta aattgtgtag gttccatacc aatggaccgt
    11041 agaagtaagt caatccattc atttgtagta aactccttgc gagccatctt gtaagcctca
    11101 atgtctaaac caggcatttg gattggatca accttttttg caataaaagg gctattccaa
    11161 cgatcattct catcatacca atattccatc gaaacaatac accagatccc cccacctaat
    11221 aatcgatcaa attttttcgg atactcttca ctaatttgaa cattttttaa tcccaggtta
    11281 gagaattctg cttcataaca atctttcttt tcatttaaat gtacagttac tttatcaata
    11341 actgtataac cacccaattc acgaattttt gcttttactt tttctgcttc atcaggacgc
    11401 acatagtttc gagcaagaat atttttaaca ttttccacac ctttttcaac caatgtttca
    11461 tccaatgacg aagcatacat accaagtaaa tattccaata cataaacagg tacattcgca
    11521 ccttctttaa ttttctttgt taaatctttt ctgacaatct ttccgggaaa gaattcagat
    11581 aactttaaaa tttcctgttg ttccactaga attcctccat gtgttcagtc attataatag
    11641 caatta
//
LOCUS       DAZUJR010000086        11444 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.086, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000086 DAZUJR010000000
VERSION     DAZUJR010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11444
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.086"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(78..302)
                     /locus_tag="ACG804_002338"
     CDS             complement(78..302)
                     /locus_tag="ACG804_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HFS4833252.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(500..2080)
                     /locus_tag="ACG804_002339"
     CDS             complement(500..2080)
                     /locus_tag="ACG804_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HFS4833253.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(2481..3857)
                     /locus_tag="ACG804_002340"
     CDS             complement(2481..3857)
                     /locus_tag="ACG804_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HFS4833254.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(3985..5073)
                     /locus_tag="ACG804_002341"
     CDS             complement(3985..5073)
                     /locus_tag="ACG804_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFS4833255.1"
                     /translation="MFWSLELLIIAALIMISSEINFIFEPIGTFFSTLFAPVLIAGFL
                     YYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQISSLASNMPDF
                     IKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSLGSIVGTIASA
                     TVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTLANYISGQAIE
                     CLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLVTVFNDPVKAL
                     LCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLGIFLGVPFYAI
                     CKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            5245..5679
                     /locus_tag="ACG804_002342"
     CDS             5245..5679
                     /locus_tag="ACG804_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4833256.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(5757..6290)
                     /locus_tag="ACG804_002343"
     CDS             complement(5757..6290)
                     /locus_tag="ACG804_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HFS4833257.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(6384..7562)
                     /gene="mutY"
                     /locus_tag="ACG804_002344"
     CDS             complement(6384..7562)
                     /gene="mutY"
                     /locus_tag="ACG804_002344"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HFS4833258.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(7555..8352)
                     /gene="recX"
                     /locus_tag="ACG804_002345"
     CDS             complement(7555..8352)
                     /gene="recX"
                     /locus_tag="ACG804_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HFS4833259.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            8459..9841
                     /gene="rlmD"
                     /locus_tag="ACG804_002346"
     CDS             8459..9841
                     /gene="rlmD"
                     /locus_tag="ACG804_002346"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFS4833260.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(10015..10593)
                     /locus_tag="ACG804_002347"
     CDS             complement(10015..10593)
                     /locus_tag="ACG804_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HFS4833261.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            10915..11385
                     /locus_tag="ACG804_002348"
     CDS             10915..11385
                     /locus_tag="ACG804_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TspO/MBR family protein"
                     /protein_id="HFS4833262.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
BASE COUNT         3368 a         2296 c         1951 g         3829 t
ORIGIN      
        1 attatagagc ccaaattttt gtgaattcca gcttatttct tggagttaaa cgcttctgtc
       61 tcagcctctt tttctttcta gctttttgat ttttctcttt tcttttgtac ttttctcttt
      121 tcattttcag ttctacgcgt gtctttattt ttaacttttt cctctttatg gatgattgat
      181 cgtacttttt gtgcaatttg ctcgtttttg tcccagtctt ttacatctaa taatcgacat
      241 aatcgtaaca tctcttcttt tttctgtttt tttctttcac gtctttgcca ttctgtttcc
      301 atgtgtcaca ctctcctttc tttaatcata tgtacgcaaa ataattttta tatttttttg
      361 attagacatt tctatgattt taatatagta aaaagagccg tcacggaaaa tccgtcacgg
      421 ctctaaacaa aatatgagag gctgtttttg tttggctatt cttattactt gatgcagggc
      481 agcttgtgtc aagacttctt tacatcaaac tttttaattt tacattggga tatttatccg
      541 caaaccagcg ttctgcaaat tggttctcga ataagaacaa cggttggtcg aaacggtcac
      601 gagccaagat attgcgactt gaactcatct tctcatccaa atcttctgga tcgatccagc
      661 gagcgatttt gtgtcccatt ggagacatga ttacttcggc gttatactca tttaacatac
      721 gatattggaa tacttcgaat tgtagctgac caacagctcc aatgatatat tcttccgtta
      781 gatatgtttt ataaagctga atcgctcctt cttgaactaa ttgatagatt cctttgtgga
      841 aggatttttg tttcatgaca ttttttgcag tcactttcat aaacagctct ggagtaaatg
      901 aagggagttc ttcataagca acttttagtt ttccttcgaa caatgtatcc ccaatctgat
      961 aattgcctgt atcatataca ccgatgatat cgcctgctac tgctttttcg acgttttctc
     1021 tcgaatctgc cataaattgt gtgacattgc ttaatttcag ttttttattt gtacgttcca
     1081 accagacatc cattcctcgt tcgaatgttc cagaacagat tcggacaaaa gcgattcggt
     1141 cacgatgggc tggattcata tttgcttgga tcttgaatac gaaacctgaa aattcttcct
     1201 cataaggact taccatctga tcatcttgtg ttttgtgtcc ataaggagct ggtgccaatt
     1261 caacgaaagt ctctaaaaaa gtctgtacac cgaagttagt caatgcagaa ccaaaaaata
     1321 ctggtgtctg atcgccacga gcaatttttt cttgattaaa tgcatctcca gcctctttga
     1381 ttagttctac ttcttctaag acttgttcat ataaggaatt ttcagttaga ggatgatttt
     1441 cgggaagcag tccatcttca tccaattcta ctaatcgttc atcctgataa ttttccggac
     1501 gataaaactc tacacgatta tggtagatat cataaagacc ttctagccct ttacccatac
     1561 cgattggcca attcatcgga taagattcga tatctaatag ctcttctaat tcttctaaca
     1621 attccaatgg ttcacgacca tcacgatcta gtttgttgat aaaagtaaat atcgggatgc
     1681 cacgtttttt tacaacttgg aataatttct ttgtctgtgc ttcgatccct tttgcactat
     1741 cgattaccat gaccgcacta tccacggcca tcaaagtacg ataagtatct tcagaaaaat
     1801 cttcatgtcc tggtgtatcc aagatattta ctcgtttccc ttgataatca aactgcataa
     1861 cagaactagt aacagaaatc ccacgttgtt tctcgatttc catccagtct gatttggcaa
     1921 aattacctgt ttttttgcct tttacggtcc cggcttgacg gatagcccca ccaaacaata
     1981 gtaattgttc tgtaatcgtt gttttcccag catccggatg ggaaatgatc gcaaaagttc
     2041 tgcgattgtc cacttgttgc tttaattttg gattattcat aacctaactc catttcttcc
     2101 attcaattat ttatattttc tctaggcaca gattgtccga tctcttaaag aaagacaatt
     2161 tcatataggg ctgtgacaaa agccgtgtag cagtctcttt ttccgagtaa acggcgttct
     2221 agagacagcc tatcagcaat aagcccaccc aagccaaaaa tacgaaaagc tgtttttgct
     2281 tggctgctct tattacttaa tgcaggatag ctttttcaca acctttgtca actactacaa
     2341 ctgaatcagt atagcatgga ttcagcgaat gaaaaagcca ccaaaccata agagtcaaat
     2401 atttttttgt cagctgacta aaagaaaaga cgtgttgctt gtttattcaa gcaacacgtc
     2461 tttcataacc aagtttccaa ttatcttctt ggctcgtcat cttcgaattc ttttctgaag
     2521 tatcttcgtt cttcttcagg ttccgcttct gtttcttccg gatcatgaaa aatgacacgg
     2581 attttaagga ttcgagaacc ttccatttct tcagaaacca gcgtaatatt atcgacatca
     2641 aacgataact tttcgccttc atccggaatc atgcctaatg ctgtaatcaa ataaccagcc
     2701 atcgtatcta catcactcat atgcagatca ctgtcaaaag cttcattgaa ctcatcaatc
     2761 agcatacgtc cttggatgat atattcgtgt tcatcgattt tttcataaag attctcaact
     2821 tcatctgatt catcatcgat ttctccgacg atttcttcta aaaggtcttc tagtgttgct
     2881 aacccaacga cgccgccata ttcatctaat aaaatagcca tctgattctg cgtctttttc
     2941 atttcatata acagatcatc aataaagacc gtttcaggaa cgaataaagg ctcctgcatg
     3001 attttcttga tatctaaatt atcaaagccg aatttatggg cagcttttag taaattcttt
     3061 gtatgaagga ttccgactac tttatctttg tcttcgttat aaacagggat tcttgaatag
     3121 ttttcggata aaacttcatt cacattttct tccacagtgt cgttgatatc aatcataaat
     3181 gcatccgttc gtgggaccat gacttctcgg gcaactttcg tatcaagaga aaaaacccct
     3241 tggagcattt ctaattcttc attattcaat acgccttcgt tttcaagcat ataacgcatt
     3301 tcatctctgg tcatttttga atcttcatca tcaaaagtca tcggcgtgat acgcgccaat
     3361 aaacttgtgg aagcagaaag cagccagacg aagggcttag ctactacacc aatcaagcgt
     3421 atcagccctg aagtgaactt tgcgacttct tctgatttat ttaaagcaat acgtttaggg
     3481 tacaattctc caaaaacaat cgatacatag gtcaaaatag ccagcacaat gatatttgca
     3541 atattttttg ccgctgtgcc gccacctaat accggagcta accgttccga taaagtatta
     3601 gctagtgaag caccagacaa aatgttgacc aaagtgattc ctacttggat tgtcgatagg
     3661 aaattatttg gattctgcaa tatttttaaa agcttttgag atttcacatc tccttcatca
     3721 gctttttgct cgattcgatt cttattgatc gaaacaacag caatttcgga agctgctaaa
     3781 aaagcattga tcaatgtcaa aacgatcaat aataaaatct gcgctaacag cgactgactc
     3841 tcagggtcag cattcataat cgcattctct ccttataaaa ttaattttta gtttacgata
     3901 gaaaaaaacg tggcactata gccacgttaa aatggtatca caaagcaatt ttctttgcaa
     3961 taaaaacaag tgtactaaaa ctacctacga ggtcgtagca attttcttct tgttttcatt
     4021 ttgcttgtct tctttgacga ttttgattat ataggaaatg atcgtcttgc agattgcgta
     4081 aaaaggaaca cctaagaaga taccaagcaa tccggcaata tttccagcta ctagaagaac
     4141 gataatgatc gttaatggat ggattttcag tgatttccca attacattag gataaatgat
     4201 attcccatcc aactgttgga cgattagcac aaccacacaa caaagtaatg cttttaccgg
     4261 atcattgaag actgttacta gaaatgcagg tgctagtcct agataaggtc ctaaatatgg
     4321 aattaggttt gtcaatcccg caatgacccc aaataagaaa gcataatcca caccaattac
     4381 catatatcct aaaaatgtga aggtaccaac gaataaacat tcgattgctt gtccgctaat
     4441 gtaattagcc aatgttttat tcagttgccc caataactcc acaatttggt ttcttctttt
     4501 ttctgggaaa aactgttgga tgtttggcac tagtttttct ccgtctttca acatatagaa
     4561 caagatgaat ggtgctgtaa tgattactac ggttgccgaa gcgatcgttc caacgatcga
     4621 acctaaacta ttggatactc cactaaggaa ttgctgaatg attgtcccgt aagaaatgtc
     4681 taattgctca aaatatttat tgatatctac ttccttgaac aaaggcaatt cggctacctc
     4741 ttttaaccag ctttctacct gtttgatgaa atcaggcata ttagatgcca atgaggaaat
     4801 ttgctgtact agacttggga tgacactaag taaaatccaa ataattgctg caactaaaag
     4861 gagcagcaca attgcgacag cccatattct tttgattttt gctttcatca acagcttgac
     4921 aataggattc aataaatagt aaagaaagcc tgcaatcagt acaggtgcaa ataacgtgga
     4981 aaaaaatgtc ccgatcggtt cgaaaataaa gtttatttct gatgaaatca tgatcaatgc
     5041 agctatgatc aataattcaa gcgaccaaaa cattagttta gactgtctaa gtttttcaaa
     5101 caatagattt cctcctttct ttcttactag tatatattat attcgttaaa aattctttta
     5161 ttcttttttt atttttgaaa acttgccata ctttttattt gttttatttt ccagtatact
     5221 atacgaaagg aaggtggcta gaccatgaaa gttgtacaaa caaaagatac aatgagcaat
     5281 atttacttag atgctgtacg gatcaggcat caagtttttg tagtcgaaca gggtgtgcct
     5341 ttgtctcgag aaatagacaa agatgaagcc cattgtatcc acttcgtcct gtactcagat
     5401 aaaaaagaac cgcaaggaac tgtacgtctt ttgcctttag aaaacggaaa aatgaaatta
     5461 cagcggatgg cgattctttc tgaatacaga caccaagggt taggaaaaat attgattgaa
     5521 gaagcagaaa actttgctaa gaatcaaggc tataatacga ttttattagg ggcacagtcc
     5581 acagctgaaa ctttttacga aaaactagga tatacagctt acggcgatcc ttttgaagat
     5641 gctggcatgc ctcatattta tatgaaaaag actttataaa aatttatttc gaaaaaagca
     5701 aaaaacagca agcttttgag aaaaatctct cactggctta ctgttctttt ttgtgtttac
     5761 ttacgcgaca attgcttgta acggttatac caaatatcaa tatagccttc cgagaacggg
     5821 ccatctccat tattgatcca gtcaaccaga atcttcacat tttcttttag gatgaagtca
     5881 atatcgttcg ggtaattcat cattttgctg tgcatctcat attcatcgac atccaatagt
     5941 cgtttctcgc cgtcaggaaa taccttgata tccaagtcat agtcgatata tttcaaggcc
     6001 tcatcgtcca gcaaaaaagg tgaagctaga ttacaataat aggaaacccc cttttctctg
     6061 atcattgcta ttacattgaa ccagtatttt ttatgaaaat aaacaatcgc tggttcgcgc
     6121 gttacccatc ggcgtccatc agattcagtg actaatgtgt gatcattcac gccgatcata
     6181 gagtgttcgc ttgtttttaa taccatggta tctcgccacg ttcgatgcaa tttgccgtcg
     6241 tgcttgtaac tttggatcgt cacaaactct ccttcttttg gaactcccat agcaaccctt
     6301 ccttaagcag cattttgtgc tttgtgtttg ggtgttcatt acaccgacat cataattatt
     6361 atatcaataa aaatgagctt tgcctagaaa ggattcctat tgtttcgatt tttctctaac
     6421 tgatctacca gtttcatttg gaccttagga aaaacgaccg aatcaaatgc atcaggcttc
     6481 aaccacttcg aagttttgtt ctcggtaaat tcttgttctg ctccctcggt tgcccgtccg
     6541 taaaaaagga gaacatgcca tttcagatga ctaaaaatat gagtaacttc tcctaaatgt
     6601 cgtgtctgcc aaacaaagag ttcctgcttt tcaaatggga gattttgctc ttcttctgct
     6661 actaggtcat caaacagatc gatttctggc tttgtttccc attctttttt caatcgctca
     6721 tactcctctt gtgtcacttc catcattgga aatgtccaca tattcgccag caatttttgg
     6781 ctatctcttt cttcaaaata atacgctcca gaatgatttt gaagagctgc actgatataa
     6841 taaacgtctt ttggctttgc tttttttgtt tttacaggaa aactcgtttg gattcctcgt
     6901 ttgttagcta aacaaaaggc ttggatcgga caagtctcac actttggaga agttggtgta
     6961 cagatagctg aacctagatc catcattgct tggttgaatt cacctggatg cttttcatca
     7021 atgattttcc gcatcgcttc atcaaagatt ttcctgctag aagcttttgc gatgtctgct
     7081 tcaatgcaaa acaatctgct gactactcgc atcacgttgc cgtcaactgc aggttctgga
     7141 agtccaaatg cgatacttgc aatcgcgcct gtcgtatatg gtcctattcc cttcaatgag
     7201 ctaatttctt caggcgtttg cggcatttcc ccatcaaatt ctgacatgat ctgtttagca
     7261 gcagcttgga tgttccgggc tcttgagtaa taaccaaggc cctcccatgc ttttaaaagc
     7321 ttttcttctg gagcatttgc tagctcttca attgtaggaa accattccat gaaacgataa
     7381 aaataatcga tcactgtgtc tactctggtt tgctgaagca tgatctcaga gatccagata
     7441 cgataaggat cacgattata gcgccaaggc aggtttcttt tttcttgttc ataccattga
     7501 atgaactgat cttgaaattc ttttgtttct ttatctgtcc atttttccca ttctttattc
     7561 actttcctct tccttttccg taatgaatcg ctggatcata tccaaatcaa atcctttttg
     7621 atataagctt tgctttactt ttagatttct ttttttaggt tcaaacctta aatttcttcg
     7681 ccatagttta tctccttgtt tgactaaata atcatattct atttcttgat ctgcttcttg
     7741 cggaagatca gctatcgctt gttggatcac ttcttgagaa aagcctttcg tcatcaatgt
     7801 ttgttggatt tttctcaata attctttttg gctttttccg tgattttttc caaacgcttt
     7861 ttcggctgtc tgatgtgcat tttgaacttg gtcttcaaat gtatattggc tgagcgcttg
     7921 ttcaatgatt tcaggtttca aacctttttg ctgcatctgc tgcgctaatt tctttggtcc
     7981 tttgtcactt aagcgcatat tcgtgcgcac ataactttcc ccatagacca aatcatcgac
     8041 aaggtccaat tcttttaagc gggctacgat tttatttcga tcttcttgaa ggatttcctt
     8101 ttcttttaag tatgttcgga tttctttttc cgatcgcaac tgataactta agtaattcat
     8161 tgctaggtga aaaccgaaat cagctccgct actcttcttg atctcttgga tagtttcttc
     8221 gtctaattcc cgtcctttta ataatcgata gcgtactaat acatcttcag atacttgtaa
     8281 agcttctcct tcagataaat ctacgcgata gaaagggcct ttgcctttac tgattctcgt
     8341 aacggttaac ataaacatcc tcctcgaaca tatattctct atcataccac agaaaatccc
     8401 cgtaatcagg tattatatgt tagaataaac cacagaaaaa agaaaaaggg agatacttat
     8461 ggcagaaaca attgtcaaaa ctggacaaac ggttcctttg aaaatcaagc gtttaggcat
     8521 aaatggtgaa ggaatcggtt atttcaaacg gttgatcata tttgttccat atgcactacc
     8581 aaaagaagaa gtactagtga aaatcacgaa agcaactcct cgctatgcag aaggagaatt
     8641 aataaaagtc aaaaaaacaa gcaaagatcg cgtagtggca ccatgtcctg tttactatga
     8701 atgcggtggc tgtcaattac aacacttagc ttatcaagct caattggatt ttaaaaagga
     8761 tctgcttttg caagcattgg aaaaattcaa accagcaggc tttcgatctt atcaactttt
     8821 gccgacgatc gggatggatg agccttggca ttatagaaac aaagcacaat ttcagttacg
     8881 aaaaaataag cagactcaaa aaattgaagc tggtttatac gaagcaaact ctcatcagtt
     8941 agtccctata acagactgct tggttcaaga acctcgaaca caaaaagtaa tgaatactgt
     9001 tgttcaacta ttgaataaat ttgatgcacc catctatgat gaacggacaa acagtggaat
     9061 cttccgcaca atcatggtta gaatcggtgt taaaactggg gagttacaag ttgtttttat
     9121 tactcgcagt aaaaaattcc cgcaaaaaaa cgcaatgatc cgtgagatca atgaacgact
     9181 gcccgaagtt gtttcaatca tgcaaaatgt ccaggcacaa aaaacgtctc tcgtgatggg
     9241 ggatgaaacg atccacttat ggggaaaaga agccattgaa gaacaaatca atgaagtgac
     9301 tttcgatctt tctcctcgtg ccttctttca actcaatcct cagcagaccg aattgcttta
     9361 tggcgaagga atcaaagcat tagatgtcca gcctaatgaa acgatcgtgg atgcttattg
     9421 cggagttggg acgatcggct taagtgtagc aaaacaagcc aaagaagtac ggggaatgga
     9481 taccgttcct caagcaatcg ctgatgcaaa aaaaaatgcg gaaagattag gatatcacaa
     9541 cactcgatat gaagtcggga cagcagagca agttctgcct aaatggttga atgaaggttt
     9601 tcagcctgat ggtatcatcg tagatccacc acgtacgggt ttggataacg cattgatcca
     9661 atcattattg aaataccctc caaaaaaact tgtttatatc tcctgtaatg tttctacact
     9721 tgccagagat ctggttaatt taagtaaaaa gttcaagatt gaatatttac agtccgtcga
     9781 catgtttcct cagactgcac gttgtgaagt tgtcgtgaag atgacgagac tcgctgacta
     9841 aatgaaagag gttgtgaaaa agtctgccct gtatcaagta ataagaacag ccaaacaaaa
     9901 atagctcttc atgttttatg aatactgtac ttgtgaccga agagttaaca ggaggacact
     9961 atttatttaa aaaaagggtt gtgacatagt ttttgtcaca gccctttttg attattattg
    10021 gatattcacg tctatcactt gataaaatgc atttgtcgta tcgctgatat tccatactgc
    10081 taaaatcaca ttatatcctt ttcgatcctg cggaagtgtg atcgtttggt tgactgtttt
    10141 tggtggaaca gttgctttgt cgtctatttt tgtgatcaat tcaaaatcac taaatttcaa
    10201 aggttgatta ggattccaag ttggtttggt aatgtagtaa tcccaagtac ttgtccgatg
    10261 ttgtgctgtt aaattccaag taatatttaa tgttcctgga ttaaccatgt ttttatgcca
    10321 tctgttagat gtctgttcat ctaaaggctc aaagccgctg actcctgcac tagcaatttt
    10381 tccatcaatg aatgtatttt tggtagcttc gatactttgc ggttcccatt gtgctcttcc
    10441 gacattttga tttaagtttc ctgctgctga tgttcctagg tatgcacggc ttcctggaga
    10501 agtaatataa ccatgcgcaa aacctggaat gctaaaaccg aacaacccta aactaactaa
    10561 cccaataaac aataacgtac taatcttttt catgtagaaa cctccttcat ttgataacca
    10621 cattgtaaac gctttattgt attaacacaa acattatgct tttataattt tatgttgaag
    10681 taaaaaaggt gaaaaaagta agatgcagat tataacagaa gtagacgaga aaagtacaaa
    10741 tagaaaacat gagaatcaaa tcatatgatc tttttcaaaa acatcattca tataaacaaa
    10801 tgttcaactt tttaataaca acaattatca atttttttct tacttcacaa actaaataca
    10861 ggtcttgctg tgagccttca tggtaaacta atattataga aaggagttag taaaatgaag
    10921 atgataaaag atattcgttt ttgggtttgt gttataggaa ttgtcatatt aggcttttta
    10981 tcagggttgc ttagcggaaa tcccggaaaa tattactatt ctttgcaact tccaccattt
    11041 gcaccaccta gctggatatt tgggccgatg tggaccttac tgtatatatt gatgggtatt
    11101 tctctttatt tgttacttaa tcacaacaac aaaaaacagc gaaacaatct tgtcggtctt
    11161 tttgtgattc agttcatttt taattttata tggtctgctc tattttttaa tttaagaaat
    11221 attttcattg cagcaatcga tattacactt ttagttattt tcttgtcagt gcttatgtat
    11281 cagttgtggc tgcatcatcg cctggcaatg tggctcatga ttccttatta tttatgggta
    11341 ctattcgcaa ctctattgaa ttattcaatt tattttttaa actaagcgct aaaaagagac
    11401 gtcctgtaat ttaacacata gaaaaagtgc cacctaagtt agat
//
LOCUS       DAZUJR010000087        11412 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.087, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000087 DAZUJR010000000
VERSION     DAZUJR010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11412
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.087"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..825
                     /locus_tag="ACG804_002349"
     CDS             <1..825
                     /locus_tag="ACG804_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4833263.1"
                     /translation="KDDVLVKNVNSNLIQDMLDYYYFEKNLSYNYVIHLKTFTGMIFK
                     FANRRYGLKYNPVNGVSLARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYS
                     LITKFLFLTGLRYGELISLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSS
                     NAKEIIDQLIEENKLIKNNKDKYIFISKNGNPISIQAYNQSLRAVSKELNLDKKVSSH
                     MLRHSHISLLTELGIPLKAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
     gene            complement(907..2679)
                     /locus_tag="ACG804_002350"
     CDS             complement(907..2679)
                     /locus_tag="ACG804_002350"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4833264.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
     gene            complement(2682..4394)
                     /locus_tag="ACG804_002351"
     CDS             complement(2682..4394)
                     /locus_tag="ACG804_002351"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4833265.1"
                     /translation="MKLILRHAKKYKVSVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            4509..5177
                     /locus_tag="ACG804_002352"
     CDS             4509..5177
                     /locus_tag="ACG804_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HFS4833266.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            complement(5244..6032)
                     /locus_tag="ACG804_002353"
     CDS             complement(5244..6032)
                     /locus_tag="ACG804_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFS4833267.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(6115..7587)
                     /locus_tag="ACG804_002354"
     CDS             complement(6115..7587)
                     /locus_tag="ACG804_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HFS4833268.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            complement(7717..8910)
                     /gene="metK"
                     /locus_tag="ACG804_002355"
     CDS             complement(7717..8910)
                     /gene="metK"
                     /locus_tag="ACG804_002355"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HFS4833269.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     regulatory      complement(8908..8987)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SMK box riboswitch (SAM-III) riboswitch; SAM
                     riboswitches modulate the expression of downstream genes
                     in response to levels of S-adenosylmethionine; SMK box
                     riboswitch shares no known similarity to SAM-I and SAM-II;
                     Derived by automated computational analysis using gene
                     prediction method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            complement(9176..9247)
                     /locus_tag="ACG804_002356"
     tRNA            complement(9176..9247)
                     /locus_tag="ACG804_002356"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9212..9214),aa:Glu,seq:ttc)
     gene            complement(9259..9332)
                     /locus_tag="ACG804_002357"
     tRNA            complement(9259..9332)
                     /locus_tag="ACG804_002357"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9296..9298),aa:Ile,seq:gat)
     gene            complement(9345..9415)
                     /locus_tag="ACG804_002358"
     tRNA            complement(9345..9415)
                     /locus_tag="ACG804_002358"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9381..9383),aa:Gly,seq:tcc)
     gene            complement(9420..9492)
                     /locus_tag="ACG804_002359"
     tRNA            complement(9420..9492)
                     /locus_tag="ACG804_002359"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9457..9459),aa:Phe,seq:gaa)
     gene            complement(9496..9568)
                     /locus_tag="ACG804_002360"
     tRNA            complement(9496..9568)
                     /locus_tag="ACG804_002360"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9533..9535),aa:Asp,seq:gtc)
     gene            complement(9587..9660)
                     /locus_tag="ACG804_002361"
     tRNA            complement(9587..9660)
                     /locus_tag="ACG804_002361"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9624..9626),aa:Met,seq:cat)
     gene            complement(9673..9762)
                     /locus_tag="ACG804_002362"
     tRNA            complement(9673..9762)
                     /locus_tag="ACG804_002362"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9724..9726),aa:Ser,seq:tga)
     gene            complement(9785..9856)
                     /locus_tag="ACG804_002363"
     tRNA            complement(9785..9856)
                     /locus_tag="ACG804_002363"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9821..9823),aa:Glu,seq:ttc)
     gene            complement(9878..9965)
                     /locus_tag="ACG804_002364"
     tRNA            complement(9878..9965)
                     /locus_tag="ACG804_002364"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9929..9931),aa:Ser,seq:gct)
     gene            complement(9990..10063)
                     /locus_tag="ACG804_002365"
     tRNA            complement(9990..10063)
                     /locus_tag="ACG804_002365"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10027..10029),aa:Ile,seq:gat)
     gene            complement(10077..10147)
                     /locus_tag="ACG804_002366"
     tRNA            complement(10077..10147)
                     /locus_tag="ACG804_002366"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10113..10115),aa:Gly,seq:tcc)
     gene            complement(10149..10224)
                     /locus_tag="ACG804_002367"
     tRNA            complement(10149..10224)
                     /locus_tag="ACG804_002367"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10189..10191),aa:Asp,seq:gtc)
     gene            complement(10243..10316)
                     /locus_tag="ACG804_002368"
     tRNA            complement(10243..10316)
                     /locus_tag="ACG804_002368"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10280..10282),aa:Met,seq:cat)
     gene            complement(10329..10418)
                     /locus_tag="ACG804_002369"
     tRNA            complement(10329..10418)
                     /locus_tag="ACG804_002369"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10380..10382),aa:Ser,seq:tga)
     gene            complement(10442..10515)
                     /locus_tag="ACG804_002370"
     tRNA            complement(10442..10515)
                     /locus_tag="ACG804_002370"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10479..10481),aa:Ile,seq:cat)
     gene            complement(10529..10602)
                     /locus_tag="ACG804_002371"
     tRNA            complement(10529..10602)
                     /locus_tag="ACG804_002371"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10566..10568),aa:Met,seq:cat)
     gene            complement(10630..10702)
                     /locus_tag="ACG804_002372"
     tRNA            complement(10630..10702)
                     /locus_tag="ACG804_002372"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10667..10669),aa:Ala,seq:tgc)
     gene            complement(10722..10795)
                     /locus_tag="ACG804_002373"
     tRNA            complement(10722..10795)
                     /locus_tag="ACG804_002373"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10759..10761),aa:Pro,seq:tgg)
     gene            complement(10805..10878)
                     /locus_tag="ACG804_002374"
     tRNA            complement(10805..10878)
                     /locus_tag="ACG804_002374"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10842..10844),aa:Arg,seq:acg)
     gene            complement(10889..10974)
                     /locus_tag="ACG804_002375"
     tRNA            complement(10889..10974)
                     /locus_tag="ACG804_002375"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10938..10940),aa:Leu,seq:taa)
     gene            complement(10991..11062)
                     /locus_tag="ACG804_002376"
     tRNA            complement(10991..11062)
                     /locus_tag="ACG804_002376"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11028..11030),aa:Gly,seq:gcc)
     gene            complement(11074..11146)
                     /locus_tag="ACG804_002377"
     tRNA            complement(11074..11146)
                     /locus_tag="ACG804_002377"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11111..11113),aa:Thr,seq:tgt)
     gene            complement(11164..11245)
                     /locus_tag="ACG804_002378"
     tRNA            complement(11164..11245)
                     /locus_tag="ACG804_002378"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11209..11211),aa:Leu,seq:tag)
     gene            complement(11253..11325)
                     /locus_tag="ACG804_002379"
     tRNA            complement(11253..11325)
                     /locus_tag="ACG804_002379"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11290..11292),aa:Lys,seq:ttt)
     gene            complement(11329..11401)
                     /locus_tag="ACG804_002380"
     tRNA            complement(11329..11401)
                     /locus_tag="ACG804_002380"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11366..11368),aa:Val,seq:tac)
BASE COUNT         3521 a         2565 c         2034 g         3292 t
ORIGIN      
        1 aaagatgatg tacttgtaaa aaacgttaat agtaatctta tacaagatat gctagattac
       61 tactattttg aaaaaaattt atcatataat tatgtaatac atttaaaaac ttttacagga
      121 atgattttta aattcgccaa ccgtcgatat ggattaaaat ataatcccgt aaatggggtt
      181 tctttagcaa gaaaacctaa gacaaacgaa gaaataaaaa aagaaaaaga tggttattta
      241 tcaaaagaag aagttcaaat gattgctagt aaacaaaaaa gttcacatca acagtcacgt
      301 tattctttaa ttactaaatt tttgttttta actggactac gttatggtga attgatatct
      361 ttgactgaat ctgattatga tggtaataaa attacggttt ctggtactta tgattacgag
      421 ttaaaaatta aaacaacaac taaaaataca ggttcttata gaaccattga attatcaagt
      481 aatgctaaag aaatcataga tcaattaatt gaagaaaaca aattaattaa gaataataaa
      541 gataaataca ttttcatctc taaaaatggt aacccgatat ctattcaagc atataatcaa
      601 tctttaagag cagtatccaa agaattaaac ctagataaaa aagtttcttc tcacatgtta
      661 aggcattccc acatttctct acttacagaa ttaggaatcc cattaaaagc cattatggat
      721 cgtgtaggac atgaagattc aaaaacaaca ttaaagattt atactcatac aactaaaaat
      781 atgcaaaatc aactagtaga aaaactagga aaaatagaaa tttaaattgc cccttttctg
      841 ccccttataa aaacaaacaa cataaaatat ataaaaagaa ccccgttata acgaggttct
      901 tttaatttaa ctttcaaata caaattgatt atgataaagt tccgcataaa atccattttc
      961 tgctaataac tcatgatgac tgccttcttc aatgacttcc ccatcacgca agacaacgat
     1021 tctatctgca ttcaagattg ttttcagccg gtgagcaatc acaaagctgg ttcttccttt
     1081 gattgcttca tccattgctt tttggatcct tgcttctgtt accgtgtcta cattacttgt
     1141 tgcttcatcc aaaatcaata aagatggatt tgtgatgatc gttcgagcaa tactgatcaa
     1201 ctgcttttga cctgtactga ataagttatt ttcttcggat atctctgtat cataaccttt
     1261 ttctaacgtc atgatgaagt catgaatatt cgcttgtttt gctgcattga tgacttcttc
     1321 atctgaagcg tccggtttgc cgaatgtgat attgtctttg atcgttccgg agaacaatac
     1381 agattcttgc aaaacgattc ctacatgtct acgtaatgca tcaagatcat aatctcggat
     1441 atctattcca tcgatgacta ctgaaccatc attgacatcg taaaaacggt ttagcagatt
     1501 catgatcgtc gttttccccg atcctgttgg accaacaaga gcaaccattt ctcctttgtc
     1561 cacattgatc gagacatctt tcaagactag tttttctgga gaataaccaa aatctacgtg
     1621 ctgcaacgca agaccttttt caacaccatc aaatgcttta ccgttttctg gtttgacttc
     1681 atctttttca tcaaatattt cattcaatcg tcttgcccct gtaatcgcta attggatcat
     1741 gctgtatcca gatgaaatct gcatcagtgg ttggtaatat tgttgtgaat actggacgaa
     1801 tgtcacaact aagcctaatg ccaccgaacg ttccaaatca ccatttaatg ctaaccagcc
     1861 gccgaaaaag ataactatcg ctgtattgac cagtgacatt ccttgcatca tcggaaatag
     1921 tagaccagaa taagcttgtc ctttgaaggt tgcttcgcga acactttgat tatgctctaa
     1981 gaatccttca atcgtttctt cttgtaagcc atttgtgatg atgacacgtt gtccgctgat
     2041 tttttcatcc atataaccat ttagtttccc cacttcatct tgctgaagat ccacatattt
     2101 ccgtgctttg cggataatca agacagctat caaaacggct actggagtgg aagcaattgt
     2161 agcccaagct aactctacat tttggcggaa catcatgatc aagatcccga caagtaaaac
     2221 agcattcgtg atgacttgaa gcaaagcttg gttcaaacta ttttgaatat tatctaagtc
     2281 actggtaaaa cgacttaaaa tttcaccgtc ttgatgagaa tcaaagaaac ggatcgtcaa
     2341 tttttccaat ttgttgaata gaccgatacg cattcggttc gttgacttcc ctactacttg
     2401 tgtgaacaaa atactataga taaagttggc tgcactagct agtacataaa acagcaagag
     2461 tttccatatt acagaaacaa atttgctttt atcgtctacg ccttgcatca agcctcctac
     2521 gtaattagct aattcttgaa aagcttcccc gatgtattga ggtgccttta cttgtagata
     2581 ggtagcaatg atcactgtga taaagataaa gaaaaaggag agtttgtacc gcttcaaata
     2641 gtgatagaaa aatttacttg cttttattag atcagtcata cttactcctc cgttcctttt
     2701 tgagtttcaa agatttcctg atagacacgg tttccagcta ccaattcctc atgggttcct
     2761 tcgccgacta atctgccttc atccaatact aagatgcggt ctgctttgac aacagaagca
     2821 attttttgtg cgatgacaat cgtcgttgtt cccttcaaat ctcgatcgag tgcttctcgg
     2881 accagctttt cagagcgagc atccagtgca ctcgtactgt catctaggat caagatcttt
     2941 ggattaccga taacgccacg agtaatggat aaacgttgct tttgaccacc agaaaagtta
     3001 ctgctacgtt cttctattgg tgcttcgtaa cgatcagata acttttcgat gaattctttt
     3061 gcttgagcaa tagaagaagc atgttccatc tctttttctg ttgcattctt tttcccttgg
     3121 cgcaagtttt gagcaatcgt tcctgagaat aaaattgctt tttgcaaaac aaaggaaacc
     3181 gtttgtctta aactcttttc atttacttga cgaagatcta caccacctac ttcaactttg
     3241 ccttctgtcg gatcaaatag acgagggatc aattgtgcta gtgttgactt cccggcacca
     3301 gtcgccccga cgataccaac catttctcca ggtttgatag aaaagctgat atctttaagc
     3361 gtatctgtat cctcaccagg ataacgaaaa gaaacatggt caaaagtgac agaacccgtc
     3421 aactcttgtt ctggaacgtc taaataagta agatctggtt cagcatctaa aatttccgca
     3481 atccgcttca gcgatacggc tgctcttgaa gtcatcatca tcatcattcc gccaataatg
     3541 attgccatca taatctgcat caagtagttc atgaatgaag caattccacc aattaacgta
     3601 ggatcatctt taacaagatc gctcacaaaa aagatcgccc caaccacagc caaattggca
     3661 gccagcatga aggacgggat catcacagaa aataatgtac cgactatgat gttgtgtttt
     3721 gttaagtcct cacttacttt gctgaatgac ttcaattggt tttcttcttg tacaaaagat
     3781 ttcactacac gaatccctag taagttttct tttgcaatgc tattcacacg atcaatcagt
     3841 ttttgaatga tcatgaagtg cttgcccatc cttgtaaatg aaagtgccgt aatcagaaat
     3901 accgtaacga taagcgctac gatgatccac cataattgcg gcatcgtgat catagctaaa
     3961 atgaaggcac caataaataa gaatggaatt cgaaaaagtg attgcaaaga aatcatcact
     4021 aaattttgga tttgcgtgat atcatttgtt agacgaacaa caagatttcc agcagagaac
     4081 tgttcgatat ttccaaatga aaatgtctgg atctttcgaa atgcttcttc tcggatatct
     4141 gcacttacgc cttgagctac ttttgcagag aaaatcgtgt tcgttacacc tgcggctaat
     4201 cctagcaaag ccagactgat caggtaaata ccaattgttt tcatttcatc attatcttct
     4261 gtaataatag cttccaatac ttgctgtagt aacttaggtt gccataatgc tgctgcaacc
     4321 atgactgcta cggacagcaa ggaaataaaa acagatactt tatatttttt cgcatgtcgt
     4381 aagattaatt tcattcgttg attacacccc tttgtttaaa ttgacaggac taatttaaca
     4441 ctgtaaaatt agaccgacta acaatttacc atgtttaaaa agataatgca atacacgagg
     4501 ttgataaaat ggaaataaag ctttctcaag caatcatcat tcaggccgcc tttgatatcc
     4561 tggctgaaac acaagctctt tcgcagcttt ccatgcgaaa catcgcaaac agaattcatg
     4621 ttcaagcacc tgctttatat tggtatttca aaaacaaaca acagctcttg caaaaaatgg
     4681 ctgaaacaat ggaagaagaa ttagcgcttc cagatccaac tttgccttgg aatgaacagt
     4741 tgctgcagta tatggaaaat tactatgacc tttatacacg tttcccttgt ggggcagaat
     4801 tagaaatcaa tactgtgccc gcttttccga gtcgattaga acatttggag caaatgatcc
     4861 aattacttgt tcgtgaagga ttttcagtca cccaaagtca tcaggccatt gcctctctcc
     4921 acaatttatt gattggacag ttaatggatc agcagcatga acagcagctt cgacaaaaaa
     4981 ttatggacgg aaatgaattt ttgaaagaaa cagttctatt tatgcgtaat tatgtagttg
     5041 aaaatcaatt agagggattt aaagaaagta tgcagtccca tgcagaattg aatgaaaaag
     5101 cactctttct aacgagtgca caaacctata ttgaaggctt atgccaacaa aataaaagaa
     5161 gagaaaacga gcagtaaaaa agctcctata gagatcacta tgtttgtgat ctctatagga
     5221 gctatctttt taagactctt tttttatttt tcttccatta gccacgccaa tgcacgttga
     5281 atccattggt cccagaagat ccagttatga tcgccaggtc cttgttcaaa ggtgaccgcc
     5341 aagccttgtt cctgcatagc agataccatt tcctgatttg cctgataaag aaaatcagat
     5401 tccccacaag ccatataaaa tcttggaact ggttttccgc tttttactag ttctttcaat
     5461 aagtattgcg gatcattttt tgaaccttcg atttgatcca atggtccaaa gatcccttcc
     5521 caaaaagatg ctttacgaac catcaaaaga tcatccattc gatttcctac agaaacagcg
     5581 cctgaaagag agattactgc tgcgaaattt tctgattttg caaggcctag ttttaacgcg
     5641 ccatatccgc ccatcgataa tccagcggca tatgtttttt ctctttttct tgttaattgc
     5701 gggaataatt catgacaaat ctcaggtagc tcttctgcaa tgaatgtcca atacttcatg
     5761 tcataaactg tatctgtgta ccagccaaga tcagtagatg gcatgatgac agctaatccg
     5821 tagtttgcta cataacgttc aatcgacgta cgtctttccc atacactatg attgccaccc
     5881 attccatgaa gtaaatataa aacaggtata tccgttgtct cttgctctga actggtgcca
     5941 atcacctttt ttgttgtttg cggtagtatc acatttagat tgacttccat ttctaacaca
     6001 ttcgaataaa tatttgcttg aataaatgcc atattttcgc cttccttagt aagaagttat
     6061 ttttgaataa ctttaaattt gaatgattcg gctacgtaca tatcttaacc gaaactactg
     6121 ttttatttta ccactttttt catgaacgaa aagcgttaag accaaagcaa tgatcacgag
     6181 taacaagcca actagataaa cggaatgtaa cccatcataa agaatttttc ttaatggtaa
     6241 caaaatatcc gcatcaatat atttagccgt ttgtggattc accagtttat tcatgatatc
     6301 tgcatcattt gttaaatttg ctgctgcaag ttctcgttta gttaccccat ttatcaataa
     6361 accaaaaata gaaaccatga ctgtttgacc aattgttcga actaacgtat taaaagaagt
     6421 tgctacacca agctggtcac gagatacact attttgtgca ctgacagtcg aggtagtcat
     6481 ggtcacacct aagcctatac cgatgaccgt tgatatagca aaaaaccata aatagttact
     6541 tctgaaaggc ataagataca accaagcgcc cccaatagct gcgattagta gtccaattct
     6601 caagacccaa tgagttttca tttgagtcat ccacttgctt gcaaggaaag aaccgaccat
     6661 ccagactagt gataatggtg ctaataccag cccaccaatt gctgcattca gccctaatac
     6721 accttgcatc cacataggga tataaacatc gattcccatc aaaaaaccac tagccaatgc
     6781 tgcagccaag ttgaccacaa caaatagtgg atttttgaat aaatgcatca tgatgacagg
     6841 atctttagct cttttttcgg caaaaacaaa aatacctaac attacgatac tacctagcag
     6901 caaagcagaa acaagcggac tcattccttc gtctcctaat aattggaacc ctaacagcaa
     6961 tgagacaagc atggccatca aactaaaact accaaaaata tccattggtt tagactcatg
     7021 tatgattttt ggttcattta aatatagcca aatcaaaata attaatagaa ttccgatcgg
     7081 cacattgata aaaaagatcc agtgccagct gatcgtttca acgatgaatc ctcccgcaag
     7141 cggtccaaaa acactggcaa tcccccaggc tgaactattc aaacctaaaa cttttgctcg
     7201 cttttcaata gaataaagat cgccgatgat cgtcaaagct actggcatca ttgccccagc
     7261 acccatccct tgaatcgcac gagcagcaat caacccaatc atgctttgag ataaaccgca
     7321 aaataacgaa ccgataataa acaataatgt cccaaaaata aagattggtt tccgtcccac
     7381 tttatccgca agttttccgt aaatcggagt aagcatagcg tttgtcagca aataaatcga
     7441 aaatacccag ttcatgattt ccattccatg taatgaaccg acaatcgttg gcatagcggt
     7501 tgttacgatt gtaccttcaa tagccgtcat gaacgttgca atgaaaatac tcactgtgac
     7561 caaagtaaca tttgtttctt ttttcatctt attcctccct ttcattatga caggatctaa
     7621 aaatagataa ataattacta tctttttcaa gaggttaact gccataaaaa aagctggaac
     7681 aaccaccact tggcgatcgt tccagctgaa tataacttat tttgctaaac ttgctttcaa
     7741 cgcatctact ttgtccgtat gttcccaagg caaatctaca tctgtacgac caaaatgacc
     7801 gtaagcagct gtttgtttgt aaatcggacg acgcaaatca agcatctcga tgattcctgc
     7861 tggccgaaga tcgaagtttt ctctcactgc agcaatcagt tcttcttccg gaaccgttcc
     7921 agtaccgaaa gtattgattg agatcgaaac aggttgagca acaccaatcg cataagctag
     7981 ctgtacttct gctttgcgag caagccctgc tgcaacaatg tttttagcaa tataacgtgc
     8041 agcatagctg gcagaacggt caacttttgt cgcatcttta ccagaaaaag caccgccacc
     8101 atgacgagca taaccgccat acgtatcaac aatgattttt cttcctgtta atccggcatc
     8161 cccttgagga ccaccaatga caaatcggcc agtcggattg atataatatt tcgtttgatc
     8221 atctaataat tcagctggaa taacttcctt cactactttt tcgatgacat catgacgaat
     8281 tgtttcatta tctactgcat catcatgctg tgttgaaata acgattgtat ctacgcgttc
     8341 cggttgtcct tgatcatcat attcaaccgt tacttgagat tttgcatctg gacgtaaata
     8401 cgttaattca tttgatttac gcaaatctgc caagcgtcgt accagacgat gactcaaagc
     8461 gattggtaaa ggcatcaatt ctggtgtttc atctacagca aacccaaaca ttaaaccttg
     8521 gtcaccagca ccaatctcat ctaatacgtc ttttttatct tcatcccgga tctcaagtgc
     8581 ttcatcaact ccttgagcaa tatcaggaga ttgttcatca atcgcaacca atacagctgc
     8641 tgtatctcca tcaaatccga attttgcacg tgtataacca atttctttta ttgtttcccg
     8701 tacgactttt tgaatatcta catatgccgt cgtagatatt tctccaaata ctaaaacaag
     8761 accagttgtt acagacgttt cacacgctac tcgtgctgtt ggatcttgtt ttaaaattgc
     8821 atccaagatt gcatcactga tttggtcagc aattttatct ggatgtcctt cagaaacaga
     8881 ttctgatgta aataagtgtc tttctaccat tataatgatt ccccctagtt aaattcggtt
     8941 acaaggcatc tccgtcctgc ggatcctttc gggaacttgc aacgaaccaa gtatagcaga
     9001 taaaacagtt ttctgctcgt attttttcat ttttttgctt aaaaaatata aaaatatttt
     9061 acattagaac tgtccaaaaa agcttagcac aatcatccat aaagataact ctgctaagct
     9121 ttttaaaatc attctttcag ataaaaagaa aaagatactc aaaaagtatc ttccatgacc
     9181 cgtacgggat tcgaacccgt gttaccgccg tgaaagggcg gtgtcttaac cgcttgacca
     9241 acgggccaat aaaataaatg ggcctaaatg gactcgaacc atcgacctca cgcttatcag
     9301 gcgtgcgctc taaccagctg agctataggc ccataaaaac taaaagcggg tgacgagaat
     9361 cgaactcgcg acaacagctt ggaaggctgt ggttttacca ctaaactaca cccgcataat
     9421 ggcgcgggac agaatcgaac tgccgacaca tggagcttca atccattgct ctaccaactg
     9481 agctaccgag ccaaacggtt ccgacgggaa tcgaacccgc gatctcctgc gtgacaggca
     9541 ggcatgttaa cccctacacc acggaaccaa tgtttttagt ttttaattgc gggagcagga
     9601 tttgaaccta cgaccttcgg gttatgagcc cgacgagcta ccagactgct ccatcccgcg
     9661 ataatatgaa aaaggaggat aagggattcg aacccttgca cggttttacc cgcctgacgg
     9721 ttttcaagac cgttcccttc agccggactt gggtaatcct ccatgtaaaa ctatattaaa
     9781 ttaatgaccc gtacgggatt cgaacccgtg ttaccgccgt gaaagggcgg tgtcttaacc
     9841 gcttgaccaa cgggccaggt aaaacaaaat attgaaacgg agaaggaggg atttgaaccc
     9901 tcgcgccggt ttcccgacct acacccttag caggggcgcc tcttcagcca cttgagtact
     9961 tccccaaaac caataagatt ttgtactaat gggcctaaat ggactcgaac catcgacctc
    10021 acgcttatca ggcgtgcgct ctaaccagct gagctatagg cccataaaaa actaaaagcg
    10081 ggtgacgaga atcgaactcg cgacaacagc ttggaaggct gtggttttac cactaaacta
    10141 cacccgcatg gcggttccga cgggaatcga acccgcgatc tcctgcgtga caggcaggca
    10201 tgttaacccc tacaccacgg aaccagtgtt tttagttttt aattgcggga gcaggatttg
    10261 aacctacgac cttcgggtta tgagcccgac gagctaccag actgctccat cccgcgataa
    10321 tatgaaaaag gaggataagg gattcgaacc cttgcacggt tttacccgcc tgacggtttt
    10381 caagaccgtt cccttcagcc ggacttgggt aatcctccat atgaaactta caacgccaca
    10441 atggaccttg taggactcga acctacgacc ggacggttat gagccgtctg ctctaaccaa
    10501 ctgagctaaa ggtccaggct cttaaaaatc gcggcggagg ggatcgaacc cccgacctcc
    10561 cgggtatgaa ccggacgctc tagccagctg agctacaccg cgaaaaagat attcattatt
    10621 taaatgaaat ggagcctagc gggatcgaac cgctgacctc ctgcgtgcaa agcaggcgct
    10681 ctcccagctg agctaaggcc ccgtgtttaa atttataatt atcgggaaga caggattcga
    10741 acctgcgacc ccttggtccc aaaccaagtg ctctaccaag ctgagctact tcccgtttaa
    10801 ttaacgcgcc caagaggagt cgaaccccta accttttgat ccgtagtcaa acactctatc
    10861 cagttgagct atgggcgcat atttgaaatg ccgaggaccg gaatcgaacc ggtacggtga
    10921 tcactcaccg caggatttta agtcctgtgc gtctgccagt tccgccaccc cggcgcgatt
    10981 gctttggcaa agcggaaaac ggggttcgaa cccgcgaccc ccaccttggc aaggtggtgc
    11041 tctaccactg agctatttcc gcgtgtttaa agatgccggc taaaggactt gaaccctcga
    11101 ccctctgatt acaaatcaga tgctctacca actgagctaa gccggcatgt aaaacttaaa
    11161 ttatgcgggt gaagggactt gaacccccac gccgtaaggc gctagatcct aaatctagtg
    11221 cgtctgccaa ttccgccaca cccgcaaaaa tatgagccgt acagggctcg aacctgtgac
    11281 cctctgatta aaagtcagat gctctaccaa ctgagctaac ggctcatatg gaggttaacg
    11341 ggatcgaacc gctgaccctc tgcttgtaag gcagatgctc tcccagctga gctaaacctc
    11401 catggataac tt
//
LOCUS       DAZUJR010000088        11410 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.088, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000088 DAZUJR010000000
VERSION     DAZUJR010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11410
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.088"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(70..1491)
                     /gene="tyrP"
                     /locus_tag="ACG804_002381"
     CDS             complement(70..1491)
                     /gene="tyrP"
                     /locus_tag="ACG804_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070908 - tyrosine:tyramine antiporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-tyramine antiporter"
                     /protein_id="HFS4833270.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(1734..3611)
                     /gene="tdc"
                     /locus_tag="ACG804_002382"
     CDS             complement(1734..3611)
                     /gene="tdc"
                     /locus_tag="ACG804_002382"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HFS4833271.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(3902..5158)
                     /gene="tyrS"
                     /locus_tag="ACG804_002383"
     CDS             complement(3902..5158)
                     /gene="tyrS"
                     /locus_tag="ACG804_002383"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HFS4833272.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(5270..5475)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5738..7039
                     /locus_tag="ACG804_002384"
     CDS             5738..7039
                     /locus_tag="ACG804_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFS4833273.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(7108..7707)
                     /locus_tag="ACG804_002385"
     CDS             complement(7108..7707)
                     /locus_tag="ACG804_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFS4833274.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            7962..8843
                     /locus_tag="ACG804_002386"
     CDS             7962..8843
                     /locus_tag="ACG804_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFS4833275.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            8856..10466
                     /locus_tag="ACG804_002387"
     CDS             8856..10466
                     /locus_tag="ACG804_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4833276.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(10543..11202)
                     /locus_tag="ACG804_002388"
     CDS             complement(10543..11202)
                     /locus_tag="ACG804_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFS4833277.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
BASE COUNT         3325 a         2281 c         2075 g         3729 t
ORIGIN      
        1 aaaaactatt cacttggcag gacctcctac taaatcagcg acaaaacgtc ggctgaaaga
       61 cttatttttt tatttttctt ctaaactttt ttctacctca atcccccaag aatctttctt
      121 gaagtgattg atgatcaatg gaataacgaa catgaccact gtgatagctg ctactaataa
      181 tgcatcactc aatgtcgctg tacctaatgt agcaaatacg acaacgatga tagagaagat
      241 cagcatgcag ctgactaccc aagctaatcc gtttccgttt ttaccaattc ggtaaggacg
      301 ttcgaattct ggatgtttct tacgcatttt aagcaatgaa acagcaatca aaatgtacac
      361 gatacaataa ataacagttg tagcatttgt aagtgtcaag aatacagcac ttacgtcatc
      421 cattacacca taaagcaaag caaataatga aataacgatt gattgtgtta gaacgacatt
      481 tctagatacg ccgtatttgt tttctttatg gaatccgaat tttggtggaa ggaatccttc
      541 acgagctact tggatgattg tttttgatgg tccagtaacc caagctgata attgtaaaag
      601 cacaccaata aataccatga agctgaagat atttccgatc acttctggta agcctaggat
      661 ttgacagtca atcaagatag gctgcgtgat atttgctaat tccatttttc catctggtac
      721 gacatttgct acaagcatcg cattgatgac attcaataaa actaatccga tcaaagcgat
      781 aaatacgcct tttgtataat tttttgttgc gtctttcaaa cgaggcatgt aaacagaact
      841 catttcgatc ccaacaaaaa taaatgtgat accagctaag tatttcaatg aatcaatatg
      901 ttccaagtca gggaaagctt ttgaccatga aaagtcacct agatagccgt ttgagactag
      961 tccgactttg aaggctgcca aaacacctaa aacgaacatg atgactactg ggatatatac
     1021 ccctagccat acaccgatgt tcccgccgac ttttgccata tcgaatttca agttcaagat
     1081 cgtgatgatc cagtagataa ctaaaataca acctaaaacg aaccagtgat tattgccaag
     1141 ttctacatta ccaaatgtgt ttcctaacaa tggtcctaaa gtagaagcga ccattaccat
     1201 acctgggaac atttgcaccc ataatagcca tgcaacgaca aatccccatt tgctgcccag
     1261 tgctgttttt acccataact gaggaccgcc ttcttgagga agcatcgtgg aaagctcacc
     1321 ggaaaccatt gatatcggac cggcaaaaaa caaaactgca aaaattgaat aaaaaatcaa
     1381 tgtccaaccg actgcggcta acgtaggaat actccgaacc gttgcacaca gtgccattgt
     1441 cagaccgata aaggtcccaa gacccatttt acttacttca gatttactca ccgttgacac
     1501 tctccttgat tttttggata aaataacggt gtctttgaag tagtttcagc aataaacgaa
     1561 acaattcagc gaatatttga ggggattctt tgagtttatt gcttgaaggg tttcttcaaa
     1621 gacaacctca aaacaaaggg atcgaagagc ttaggtctcc ccttgctctt cagatccaaa
     1681 catgcgtcag aaacagttag tattcaagct gttttctaac atgattacct tgcttatttt
     1741 gcttcgcttg ccaataattg gtctgcgtag attttttcca atttttcttg aagagctgct
     1801 ttgatttttt cagcatattc ttcaaagtgt tcttctttgt tcatgtatgg tgtcattacg
     1861 ctggcacgca atacagttac ttttccggca cggttccatt cttcatctga gaatcctagt
     1921 tggttcacaa attgtaatgg gctgttgcca tagtctggga tagcaaagtc agtatgtgaa
     1981 gttaagaact cattaccgta aatgcttcct ttcacgtatg aagaataatc atatacgtca
     2041 tggttcaatt tattcattgc aactaagtca tcgttgcctt tttctttgaa tacatagtct
     2101 accatattga aatctggata agttaatgga tgaacttcga tttctttgtc tcctacttta
     2161 aatgacaagt cattcaagaa gttgtagaaa cgatgtgcac cttcgattga tgcacccatt
     2221 aatttaccat atcctgtgac attcaaaggt aagacatggt gtgctgccca aacgctggct
     2281 gctgttgccc ctgcttttga accttccaag atataagccc caagtaatgc tgggatatct
     2341 gcgccttttt caaatacata tgtcgcaaag taagagataa cgtctctcat gcggatatct
     2401 ttgatgacga taccaccggc agaatatgga acatagccca ttttatgtgg gtcaatcgtt
     2461 acagattctg cttcttcgat tgctttatat gcactgtgta cttcttctaa gatataatct
     2521 ttgttttctg taaagacatt gtatttgtaa tgaacatctt ttaaatcttc aaatggaatg
     2581 aagttgttgt cttcgtctaa gaaaatcgca cggccgtatc cgccataagc agcatctacg
     2641 tgtaagtaga agtaaatacc gtctttttct aatacgcgac gcaatgcaac gattttatcg
     2701 ataccgtcga ttgctccttc ttctgttgat cctacaacac cgactacacc taggattggt
     2761 gttttttcag ctgctagacc acgaacgatt ttttcaagtt cgttgatgtc catgcgatag
     2821 ttgtggtcaa ctggcactgg aatcacttgg tctaaaccga taccgatgat gtcggcagct
     2881 tttagccatg aatagtgttt agtttgtgga accaaccatt ttcctaattt ttctaaatgt
     2941 tttccgctac gtgctgagtg agctttgatt tcgtcgattt tttctgggac gctgtctaac
     3001 agattcatga tttcttctgt tgacaagttc attaattccc aatcgctttt tccagcaact
     3061 agttcaggtg tcacttcttt cattgcaagc ggcaatgatt tgatgttgcg ggcataccaa
     3121 agtccttcta agtttgctaa agaaccatca gcaacgatgt ggccccagcc atctttatag
     3181 ctcattaatt ttgcaaattc cattcctact tcttcttcca tttggcttgt tgcaggagaa
     3241 gattcatagg caacgttatt accattccat agcatagcaa aattgtacgc tagtaaagat
     3301 ggcatcaatg tttcagagtt catatgaccc cagtaacgtc cggcattatg ccaaggaacg
     3361 gaatgggtac gcatccgcgc tgaaatttct gatagaacat cctttgtttt attcacagtg
     3421 tgttcaaaac tagcactgct tttttcttct ggcgtaataa taggcatgtc ttgaggcatg
     3481 tagttttgac gccagcctaa atgttcatcc accaattcat tcaacaaagc tttatagatt
     3541 tggccgttct cagctttgtc cccaatgaat agggcattta ggtttagatc tttcgacaat
     3601 gattcactca tagtgaaacc ctcctaaaaa aatatttaaa ttttgtcgag ccctacatta
     3661 cacctgttct tctattctgt aaactaagtt ttggcctgat ttttaatcat attttaatat
     3721 gtatcaatta tccgaattgt tcacactttt gaaataatta aaaaaaacga gggaatttac
     3781 aaatgtaaac tccctcgcaa agattgtatt aacgacaacc agcgttctat tttaggatgg
     3841 gtttcaaaat tggaatgttg taatagtatt tccctttttc aaggtaaaaa cttactaaat
     3901 tctaatcaat tactttggcc aaaaagtaat ttttcttacc ttttcgaata accacaaact
     3961 taccatcgaa ttcatcggat ggatttatga caaaatttaa atcggtaacg cggtcaccgt
     4021 taatacttat agctccgttt gaaacatctt cacgtgcttg acgtttagat ggttcaattt
     4081 ttgtggaaac aagcagttcc acgatatttt caggtgtgct tgaaatttca acgttcggca
     4141 ttttaccgaa tccttgcgcg atttcttccg catttagttc tttaatattt ccagagaaca
     4201 atgcttgcgt tattttttgc gcttctttca agtcttcttc actatgcaca aatcttgtaa
     4261 cttcttctgc caaacggcgt tgtgcttcac gtttctcagg ttctgtctct acttttttcg
     4321 ctaagtcttc gatttcttct tgagacaaga aagtaaagaa tttcaagtat ttcactacat
     4381 cgcgatcatc ttgattcaac cagaattggt agaactcaaa tggtgaagtt ttcttcggat
     4441 caagccaaac ggcaccgcct gcagtttttc cgaatttcgt tccgtcagcc ttcagcatca
     4501 atgggatcgt taaaccgaac gcttctgctt ctggtccttc taattttcgg attaggtcta
     4561 atccagctgt gatatttccc cattggtctg ctccaccgat ttgcaattgc acatcgtatg
     4621 ttttatgcag atgcaaaaag tcgatagatt gcaggatttg gtaagtaaac tctgtaaatg
     4681 agattcctac ttccaaacgg ctggcaacga tatcttttgc taacatcgtg ttgatgttga
     4741 agtttttacc gtagtctctc aaaaattcaa gtaaagagat ttttgacaac cagtcgtagt
     4801 tgttcacaaa tgtgatattt gcatctttac caaacaattt tctcatttga ttggaaagtg
     4861 cgtccacgtt atgttgcact tgttccatcg tttgcaacac acgttctgtt ttgcggccgc
     4921 ttgggtcgcc gatcgttcct gttccgccgc caatcagaat atatggatga tggcctgcca
     4981 attggaatct tttcatcatc ataaatggaa tcaaatgtcc gatatgcatc gaatcaccag
     5041 ttggatcaac gccgcaataa agtgaaatgc tcttttcttc aacgagctcg cgaagtcttt
     5101 cttcgtttgt ttgctgatta atggcgtcgc gccaagttaa ttcatcaata atattcattt
     5161 tactgacctc cgtgtagttt ttttatgaaa gcaggaacct gctagcatgt gtaattaatt
     5221 atttcttcag gataggatag gaaataaaaa aagtcccttg gcatataagc caagggacga
     5281 aatctcgcgg taccacccaa tttgtatgtc tagatatcca acatacctct cgaacattta
     5341 acgctgtcgc gtggcaatca ctgccaaaga ctcctgaaat gtaattcgct ttaaagcatg
     5401 tactggtttg cagcgaccac cagctttctg aaacattggc tttaacaact acttcgtttc
     5461 gatcttcgtc ttgttattat taatatgtgt ctatcataga gcgcaacttt ttctttgtca
     5521 acagaaaaag gatatttttt ttaaattcct cattttttct tttttgaatc cgctctaatt
     5581 ccgaacattt tattttcaat tattgttaaa agaaataact ttttctgtat tttttctgca
     5641 atttatcgag aagtcacttt actttgcctc ttattctttc ttcgttacaa taaggaatgg
     5701 gacaagtaaa aaaatgaaaa agcaagggac gaggtatatg gaaaaaaagc aaaaaattat
     5761 tttaggagcc acttctgctt taactatcgt tattttaatt ctaagtttgt tttttgtcat
     5821 ccgatcatct acaaaaaaag aaccaatcat tcctgaaaaa aaaataacag aaaaagcaaa
     5881 agaaccgaca gatgataagc aacaactagt tactcaagca aaaaatctgg ctcaaagcta
     5941 cgattatgac caagcgattg cgttattgga aaaagatagt aagaacggat ctactgaaac
     6001 acaacagctt cttcaaacac taaaaaagga gaaagaacaa ctgatcgact ggtctgatcc
     6061 tactcagatc tctcatgtct ttttccacag cttgatcgtg gacccgcaaa aagccttcca
     6121 ctctcaacag gcacaaggat acaaagatta tatggtgact gttgaagaat tcaaccgttc
     6181 gatcgaacaa ctttatcaaa atgattttgt tttagttaat ttgaatgatt tgatccaaaa
     6241 agacgaacaa ggaaatcttt cctttaacgg gcttgcgcta cctgaaggaa aaaaaccatt
     6301 ggttctttca caagatgatg tcagctatta tgaatatatg gataattccg gttttcctag
     6361 ccgattggtc gtatcaaata acaatgaaat caaaaatgtc tataaagaga aagataaaga
     6421 agaaatcggt gactttgaca tggttcctct gatcgatgcc tttgtcaaga aacatcctga
     6481 tttttcttat cgaggcgcaa aaggtacctt ggccctgaca ggttacaacg gagttttagg
     6541 ttatcgaaca tcaaaatctc aatatggaga caatgaaaaa acaaaaaaag agattaaaga
     6601 agctaaaaaa gtggcggaac agttgaagaa agacggctgg agctttgctt cccatacatg
     6661 gggtcacttg aatatgactc aagcttcact agaagatgta aaaaaagaca atgaattgtg
     6721 gcagcaagaa gttgcaccta tcctaggaaa aacaaatatt ctgatttatc catttggtgc
     6781 agacatcagc gactggcagc cttattcagc agaaaatcaa aaatttgctt acttgaagag
     6841 tcaaggtttc gatattttct gtaatgtcga tgcttctaca ccagcttggg gacaattagg
     6901 tacggatttc tatcgaaatg ctcggatcaa tatcgatggc attcgttttc aatctgattt
     6961 agacggaaaa aatcctattc ttgatccatt catcaatgtc catgatgtct atgacaaaga
     7021 agcacgcgaa tctgcttgat tttacgtcat ttatgaacca aaaaagccga actgacattt
     7081 tatcgtcagt ttcggctttt ttatgcttta tttcttcttc ggtgcgattc ccttgatcag
     7141 gacttctgtc cattctgctg tatatggaag cagttttgcg tatatctccg gcttagaaat
     7201 tccttctacc attgcttgaa aatagaggat caagaactca tccgaatatt tcaaatccac
     7261 ttttccttct ttccgccctc gatggaaaag atcaagcatg atactgaaac tttcttgcgt
     7321 atacgcatcc atcgcgtcag aaaattcttt tttttctttt tttgtatagt atgtcatcaa
     7381 atcgatataa aattgtttgt tcactcgatt gagataacgg attttgtttt cactcatggc
     7441 aatcagtgtt tcttcaaatg gaagattttc cgcaatcaac gctttcgctt cttgccctaa
     7501 atcattcata aatgcaaaaa atacttcata aatcagccct tccttgctgc caaaatattt
     7561 aaaaatcgtc gctttactta cctgagcgtt ctcagctacc ttatccattg tcactccagc
     7621 ggttcctatg tctgtgttca tcaagtcaaa agctgcttgt aaaatctctt tctttttctc
     7681 ttgtgctctc ttttcaaaac cgttcatttg tagagcctcc cgtaatttta aacttttata
     7741 atatatatag ttcaaattta ttctgaggtt tattataact atctattgag aaagtatcaa
     7801 gctagcaatt ccttgtttat gaattcattg acagaaattt ataaaaagaa tattatgtac
     7861 taaaataata aaaaaaagtt ttataaaaag gtataaaacc tttttattaa actatttaat
     7921 cttgtttagt atatattttt agaaaaagga gtggggtttt tatggcagaa atcgtcaaag
     7981 tcacacattt gaaaaagagc tttggtcgtt tcgaagcttt aaaagatgtc tctttcaccg
     8041 tacattcagg tgaagtcgtt ggatttatcg gaccaaatgg ttctggaaaa tccacgacga
     8101 ttcggacact tttagggatt ataaaaaaag acggcggaac ggcaacgatt tttgggcaag
     8161 atgtatggga agatagttta tctatccatg aacgtctttc ttatgttcca ggcgatatct
     8221 ctttgtgggg aaatttgact ggaggagcga tcatcgatct cttcatgaag cttcatggaa
     8281 aagggagtgc tcaaaaaaaa gatgaactga ttcaacgttt ctctcttgat cctaagaaaa
     8341 aagcaaaaaa ctattcaaaa ggaaatcgcc aaaaagtggg cttgattgct gctttggctg
     8401 ttgattcgga tctctattta tttgatgagc ctacttctgg tttagatcct ttgatggaaa
     8461 cgattttcca agaagaagtt gaaaaattga aagaacaggg caaatccatc ctactttctt
     8521 ctcatattct cagtgaagtc gagcgactag cggataaagt cgtgatcata cgcgaaggaa
     8581 cactcgatga agaaggaaca ctcgatgaat tgcgtcattt gactcgttcg accatcacta
     8641 tagaaacaga agcagagaat agtcacttag cacaattgaa cggtgtccat gactttgtgc
     8701 aaaaaggtca cctcgctcaa tttgctgctg ataacgaagc tttcgatgtg attttagctg
     8761 aagcgtccaa attaggtgtg aaaaaatttg aatctattcc accgactctt gaggatttat
     8821 tcatgagaca ttatgaagga tgaggaggaa gcgaaatgac tgataaattt tcacgctggt
     8881 ccaccctttt ttctcaaaac cttagccgtg actggaaaaa gatcctgata tggctagtcg
     8941 gtgtcactgc tttttctggt ggttttgtcc ctgcgtttga agaattgact tccggacaag
     9001 gattagctgg attatacgaa accttgcaaa acccggcaat gattgcaatg gtcggaccaa
     9061 ctccagcttc gaatgctgct gagtatactt taggagcgat gtatgcaaat gaaatgttgc
     9121 ttttttgcag tttgtttgct gctgtgatct ctgttttaca cgtggtgagc caaacgagaa
     9181 aaaaagaaga acttggtctg attgaactta ttcgttcctt tcgagtcgga cgtcaagcaa
     9241 actctttagc tgtcatcgct gaaagtattc tgatcaattt gcttttagca atatcgatca
     9301 gctgtacgat gatttttttc caagcggatt cgatcactgc agaaggtgct tggctttttg
     9361 ggctatctgt aggtagtatg gggattttgg ggagtgccgt tgcactgttt gctgcacaac
     9421 tgatgccaag ttcagccagt tcgaatggtc tgtctttagc gtttttaggt ggactttacc
     9481 ttctacgagc aataacagat gtagctgatt cctccctttc gatgtggaat cctttaggct
     9541 ggtcttattt gacctatcca tttacaacta acaactggat tcctttgctt tatttgtttt
     9601 tgttcagtct aatcttgata atcagttcat ttgttttaga ggaacatcga gatttgaaca
     9661 ccggctatat ccccgaacgt gaaggaaaac cgtatgctaa acgttctctt ttatccttgc
     9721 gtggtttatt attctatcta aataaaggga tgacaatcag ttggcttatc acttttggtt
     9781 tgatgggggc ggcatacggc tctatctacg ggaatatgca acagttttta gaaagtaacg
     9841 acttaatgaa acagatgttt atccaatctg gcgtctcaat tgaaaaaaac tttacaagca
     9901 cgatcatggt agtcttgatt tgtctagctg ctattttacc aattgctagc atcaatcgtt
     9961 tatttacaga agaaacccac ggacgtatga atcagctgtt cgcaacaaaa atttctagga
    10021 accaacttta ttggaccaat atgttactag ctattctatt tgctatattg gcaatcctga
    10081 ttagttctgg tgcactaggg ctttctgctt tggcttcgat gaaggatgcg aaagacatgg
    10141 atctattgat gtttcttaaa gccgggttca atttcctgcc tgccgtttta gtgtttatcg
    10201 gaattagtgg ctttctattc ggatggcttc ctcgaatcgg taaacttgct tatatctact
    10261 tagcttactc ctttgcactc aattactttg gcggaatttt ggatttacca gaatggtttt
    10321 ccaaaacagc tgtccctagc tgggttccac ggatgccaaa cgattctttt gatctttccg
    10381 tgttccttac gttatcatgt atcagccttg cactgttcgt ccttggttct attggttata
    10441 ggcgaagaga cttactagaa ggataataaa aaagcatgta caatttcatg ctagcctcca
    10501 aatctgggtc aaaaatccaa catttggagg tcattttttt atttacaagt cttctaactg
    10561 ctctttatca atgatccaga cttctcgatt ctttcttttt acataaccat tctcctctaa
    10621 taatttaaat tttctagata aagtttcggg ggtcgtaccg ataaatgcag caagttcttt
    10681 cattttcatt ggcaggaaaa agtgatcctt ccctgtcgct ttagctaagt caagcagata
    10741 gacagcgact cgttcttcta ctttttccat catcaaaaaa gttgtctgct gctgtacttt
    10801 tgttaatttc tcaacgttga ttgctaaaag tttcagacta agggcgggat aatgcagtaa
    10861 gagttccgag aaatcttttt gtctcaatat gcaaatttcc gttttttcta gtgcttcgcc
    10921 aaataaagac tcatttggaa cgcctagcaa ctggctctct ccctcatatc cgcccggctc
    10981 tattactcgt aaaagctgtt cctttccgct agcagataat tgatacactt tcatactgcc
    11041 ggaggccacg atcactaatt gaggttctcc attcggcgca agaatctgtt ctcctttttc
    11101 cacatagtga tgtttgacaa gtgcgtgtac tttttcttga tcttgctgta ctaagtgatt
    11161 gaacaaagga acaaatgaaa cacataaatg atcatgactc ataatctctc ctccttctaa
    11221 acagctattt ctaataaaga aacataactt cccttattcc aactgataat tttcttttat
    11281 catagcataa acgtcaagcg aaccagatac cagcaaatag agtggatttc tttttgtccc
    11341 ttgctttatt ttccttcttt tgagacctta agtaattgat tcctatcaat tttttaaata
    11401 tttacttttt
//
LOCUS       DAZUJR010000089        11273 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.089, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000089 DAZUJR010000000
VERSION     DAZUJR010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11273
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.089"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..637
                     /locus_tag="ACG804_002389"
     CDS             <1..637
                     /locus_tag="ACG804_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833278.1"
                     /translation="STTKFANSFWFLENINETVEKNGVYKGDFHFQNAETIEREHHYF
                     DLLVNTVVELAKWAKSNETYSQVLKRIMSQETSFIYELSKSNLKYTYNEDELEILDNP
                     ENSQWIKELKREDFIETLRILKSLFDLKLAKATIMGIERDSYYWEEIGLYAPQIEGED
                     KEKRIDNIINYINSLSEPLKCRGLDFIGTLGWTETYYEKIYKEIIEQYFPK"
     gene            820..3495
                     /locus_tag="ACG804_002390"
     CDS             820..3495
                     /locus_tag="ACG804_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /protein_id="HFS4833279.1"
                     /translation="MKMNHTSIQKHLQLLNTLGISYVNLRTFSTLNKKTVSHIFSTAD
                     SQAIINYLEKQKLSEGTVNITYNPIKQEVITQKKHSVRDNDIEKIRFVFIDIDPKRKE
                     GSATDSEKKKAENVMEQVERYLKEKRIESFVKVDSGNGYHIFLPINEQPNNHETILTI
                     QNFLQLLHRRFGVEDEVDIDTSVYNPSRLCKLVGTPAVKGKSTKERPHRLSSFLSIPD
                     NIDRSNCFKILEQIVEENSMMSTSRVKSHPSFREVLPFIQADYKQWLAHYPELTYTIK
                     EGDHKGVTLLIFDECPLRKHTNNSNGSCLSVTADNKIRFHCLHASDKNKDIQDFVKKY
                     PLPKPVNPSVESLESNQEYYFDQFKLNQEGVFLVKEGQEEKVACPMFIKQIRKNIEQK
                     VITLVLAYYVDHCWDEIEIEGGCLQTNNFKQLAKHGLIIKARREAEVVDFLQIQRENA
                     PIFFEHESLGWKKENEAMIFQLQDSFGREIPSVLTKNSCYQLTTNGTEAEFDALVHKY
                     VLGTNLELAWSIGIASIVLGYLNVTKANTFLSLLINLQGKSTTGKTTTLHFIASLFGN
                     PTTVLRNMNATNKAIIKLASNNQGGVPLILDELGAATQNNFSSLIYQLASGEERLRLD
                     SNCQLMPQETFSVLTLTSSEERLENYFNEKLTGLKVRYIEFSDIKFTKDANHAEKVKS
                     LSSNTFGWGIKLFLLKLFEQGIAKIEATFVEAQKKIWAVLPEHSLKQRIGNNLALIYS
                     GALLIQDILGYPLRLEHIQTVLINSYEQLIVDTSLGSEQTVFDRVKTLLVMNSHKFLT
                     NSDNKHTPSTIWGKVSIQKNGDIKVNIFPIPFEDLLRREFQVKDLTYLFRQLLDSGNM
                     CAEKGRRTKRIHMNRQVLPTYEILLPSSLKSYFRL"
     gene            3677..3916
                     /locus_tag="ACG804_002391"
     CDS             3677..3916
                     /locus_tag="ACG804_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833280.1"
                     /translation="MTKNKMTLKAEVLLYIQEHFSNQAFFTKPIYLAFEIRGVSAGSI
                     GGTLQALKNEGYLENHFVQRSFNGRVAKEWYLVHS"
     gene            3932..5305
                     /locus_tag="ACG804_002392"
     CDS             3932..5305
                     /locus_tag="ACG804_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFS4833281.1"
                     /translation="MRVACYDRTSVYEEAKISNDAQYDAVKEYVLEKYEQIPQRFSDK
                     GESGGKADRPAFRQLRAWVCASEEEGVIYVWRYDRLARQAKIALEFIELCQQHQVQVY
                     SISEPLPASFSHASTNKLFVQLLFTFAEQQRNVIIENVRAGLAYKKQQRQYLSSAVPY
                     GYRLVNGKIQQEAHEAKVVRHIFQLYLTKKYGYKKLCQRLTQQKFFFRERPFQPYHIY
                     SILKNPLYYGEIKGGSLGKYLGTFEPILSKTIFLQAQEIRQSRCTAKKDTYPYLLRQK
                     IRCPFCGRHLSSKYQWNTKKTKTLHYYHCTDRSCQGIFLRAERVESEVLEKIQAFFQY
                     EGVYQALIAQLTQQLAEKRKDEKHKVIQQKKQEAQWLKAFEEGNCSLEELKQQLQALQ
                     KPRSTSSFLSLQQCEAKVKEWLQLKDLSSRQLLCDHVCRIEVTKEKTVCGIYFRQMTQ
                     NILEGNE"
     gene            5309..6946
                     /locus_tag="ACG804_002393"
     CDS             5309..6946
                     /locus_tag="ACG804_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFS4833282.1"
                     /translation="METTPTKRVALYIRVSTQEQALEGHSIQAQEQNGRQFAERMSYE
                     VVEVYADEGISGKSTKNRFAYQRMMNDARNHRFDLLVIWKLTRLGRNMLDVLQTVEEL
                     LRYDVGLHSISEQFDVTTSTGKLMLQLLGSFGEFERNQIAENVQMSMQSLVKDKKRYA
                     GGRRLGYVSGIDTNGQKQLVIEPEEAKIVRLIYAKYLGGAGYRAIANFLNRQGYQTVK
                     KNAFSTTAVKDILRNKIYAGYLEYARYINWETKRRKGKNPKPILVKGTHEPIISEEDY
                     QKVQERLVLEGKQPKWNHTGENVLTGLLRCPECGAPMAASNVTNTLKDGTKKRIRYYS
                     CSVFRNKGASVCHANSIRAEQAETFVADRLKEIVQLPEVLPRLVAALNEEIVRQSQPL
                     EQELVVLLERKEELKTKIEKWEAALEDSPELFPMLKDRLDELTEKRRQLHIRENEILG
                     IFQQQGEPIQVKDVQRILTSLDRFLAQSEKKQVKALYRTFIEKITFDPNYKEILEITM
                     KFTPAVVQQLNEQYQIAVSKTKDTAIFVLKTPFTLTI"
     gene            7109..8041
                     /locus_tag="ACG804_002394"
     CDS             7109..8041
                     /locus_tag="ACG804_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833283.1"
                     /translation="MKKMGKCILCEKYTELTKEHVPPKKSGNTGGKKTRTGNLDDFLK
                     SDFTKGDFPKGIKRKPQGNVYYTLCSKCNSFFGSEYVEEYIRFAEDNKNFLYNNTSLK
                     NGKSDLTHSIKKMNSLRVAKAIVAMFFSLNGDEDSMDKPFLDSVREYLSNPKSTLFPH
                     EDYKIIMNYYLPIGAPQNSKIKIPNDIVNDGDTHNVIKGFMPLDLSTGRKIRFSEIQY
                     EGIGFTLIDLKNSTFEIKEGLDLKNLLCADDKIKKIQLYKVPILTPTVLTMLEMENNI
                     NYIDSGSDLLIRWQVITNFLMELKKYSNTQTKFS"
     gene            8157..8477
                     /locus_tag="ACG804_002395"
                     /pseudo
     CDS             8157..8477
                     /locus_tag="ACG804_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328113.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            8655..9014
                     /locus_tag="ACG804_002396"
                     /pseudo
     CDS             8655..9014
                     /locus_tag="ACG804_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit M
                     N-terminal domain-containing protein"
     gene            9078..>11273
                     /locus_tag="ACG804_002397"
     CDS             9078..>11273
                     /locus_tag="ACG804_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFS4833284.1"
                     /translation="MEELKERIVNYVIENSEIKNKWGNNTAQKISEKLNVSRNIVSQY
                     LNEFVKDGEFGKINTRPVIFFSLPEKVPNQQIFSSSEEAEKWYDSSFRVGIERVIGSQ
                     GSLRNVIAQIKAAIYYPPNGLPILLHGETGTGKSYLANYVYKDLLANNYIEEKASFIS
                     VNCSEYANNPELFLSNFFGHVKGAYTGAEDGRKGLAELANNGVLFLDEIHALSNECQE
                     KLFQFMDTRKFHRMGDNENWYTSSCWIIFATSEPPEDKLLSTLLRRIPVKLTLPTLDS
                     RSLYERKQLIKIFFKSEEERLAKKILISQQLLDFLLNYRFSENVGNLKNIIQLTCANA
                     FYFLDDLEELYIQMYHLPQWVNFNGMKVMKRQNELKYIQMDDLEKVDEVFNINELIEY
                     LYQTWKKDTDKQQLFEKYDRYFRQKNVDIQNNSALTYPTYQEIRFRQYVKEIERDFQI
                     EFDYYYLQITSIFLNSWIYQIQLTSDDKLYSFINDINSWCSREVQLVNRFIQIGDIYL
                     TKIQKNVLVILFKLMCSKEFQQKRLALILAHGDLTATCIASTANRIVERYIYDAIDMP
                     LMTSSSEIADKINRYLQECTGYEEIILLVDMGSLEKIYLNLELDAQKKFGLLNNVSTR
                     MAIDVANQILLDLPLKQILEQVKENQNVDYIYESSNIKKDMIVCSCASGLGTSFKLKK
                     ILEDSFPRDTDLVIETCDYYSLVNENYLSELRKENNILFIVGTLNPHLED"
BASE COUNT         4051 a         1672 c         2182 g         3368 t
ORIGIN      
        1 aagtacgact aaatttgcaa actcattctg gtttttagaa aatattaatg aaacagtgga
       61 aaagaatgga gtttataaag gtgattttca ttttcaaaat gctgagacta ttgaacgaga
      121 acatcattat ttcgatttat tagtgaatac agtggtagaa ttagcgaaat gggcaaagtc
      181 aaacgaaact tatagtcaag tacttaaaag aattatgagt caagaaactt catttatcta
      241 tgagttaagc aagtcaaatt tgaaatatac ttataatgaa gatgaacttg aaattttaga
      301 taatccagaa aattcacaat ggattaaaga gttgaagaga gaagacttta ttgagacact
      361 aagaattcta aaatcgttat ttgatttgaa attagccaaa gctaccatca tgggaattga
      421 aagagattca tattattggg aggaaattgg actatatgct ccccagattg aaggtgaaga
      481 taaagagaaa aggatagaca acattattaa ctatattaat agtttaagtg aacctttaaa
      541 atgtagagga cttgatttta taggaacatt aggatggaca gaaacatact atgagaaaat
      601 atataaagaa ataattgaac aatattttcc taaataattt aataaggatt gatttattgt
      661 aaaagaaaaa agttgtgatt ttggaaatca caactttttt cttttgtcaa gattttgagt
      721 gggatatatt tttgtagaac tgaagatcat gaaattatga gaggttggag gtaatgtagt
      781 catacaaata aaaatttttt agaaagtgag tggtaattaa tgaaaatgaa tcacacttca
      841 attcagaagc atttacaact gttaaataca ctggggattt cttatgttaa tttgagaact
      901 ttttctacat taaacaagaa aaccgtttct catatttttt ctactgcaga ttctcaagca
      961 attattaact atttagaaaa acagaaattg tctgaaggta cagtaaacat aacttataat
     1021 cctattaaac aagaggtgat tacacaaaaa aagcattctg tgagagacaa tgatattgaa
     1081 aaaattcggt ttgtatttat tgatattgac cctaaaagga aagagggaag tgcaacagat
     1141 agcgaaaaga aaaaggcaga aaatgttatg gaacaagtag aacgttattt gaaagaaaag
     1201 agaatagaat catttgtaaa agttgatagt gggaatggct accatatttt tcttcccata
     1261 aatgaacaac caaataatca cgagacgatt cttactattc agaattttct tcaattactt
     1321 caccgaagat ttggagtaga agatgaagtt gatattgata cttctgttta taatccttca
     1381 agattatgca aattagttgg tacaccagcg gtcaaaggaa agtccacaaa agagcgtccg
     1441 catcgtttat ctagtttcct ttctattccc gataacatag atagaagtaa ttgttttaaa
     1501 attcttgaac agatagttga agaaaattcc atgatgtcaa cctctagagt aaaaagccat
     1561 ccatctttta gagaagtgtt accttttatt caagcagact ataaacaatg gttagctcac
     1621 tatcctgaat taacttatac cataaaagag ggcgatcata aaggagttac cttacttata
     1681 tttgacgaat gtccattaag aaaacacacg aataattcta atggttcttg tttgtctgtt
     1741 acggctgata ataagattcg atttcattgt ctgcatgctt cggataaaaa taaagatatt
     1801 caagactttg taaaaaaata tccgttgcca aaacctgtaa atccttctgt agaatcatta
     1861 gaatccaatc aagaatatta ttttgaccag tttaaactga atcaagaagg agtatttttg
     1921 gtgaaagaag gtcaagaaga aaaagttgct tgtccgatgt ttattaagca aatacgcaaa
     1981 aatatcgaac aaaaagtcat tacacttgtt cttgcctatt atgtcgatca ttgttgggat
     2041 gaaatagaaa tagaaggtgg atgtttacaa actaataatt ttaaacaatt agcaaaacat
     2101 ggcttaatca ttaaagctag aagagaagct gaagtcgttg actttttaca gattcaacgg
     2161 gagaatgctc caatcttttt tgaacatgaa tctcttggct ggaaaaaaga aaatgaagca
     2221 atgatttttc agttacaaga ttcttttgga cgtgaaattc cttctgtatt aactaaaaac
     2281 tcatgctacc aattaacaac taatggtaca gaagcggaat ttgacgcatt ggttcataag
     2341 tatgttttag gaacgaactt agaacttgct tggtcgattg gtattgcttc tattgtgtta
     2401 ggctatttaa acgttacgaa ggctaatact tttttgagtt tactaattaa cctacagggc
     2461 aagagcacaa cgggtaaaac cactacgtta cactttattg cctctttatt tggaaatcca
     2521 actacggttc ttagaaatat gaatgctacc aataaagcca ttataaagct agcatcaaac
     2581 aatcagggag gtgttccact aatactagat gagttaggag cagcaactca aaataacttt
     2641 agctcgttga tctatcaatt agcttcagga gaagaaaggc taagattaga ttctaattgt
     2701 cagcttatgc cacaagagac tttttctgtt ttgaccctta cctcttctga agagcgtttg
     2761 gaaaattatt tcaatgagaa attaactggt ttgaaagttc gatatatcga attttctgat
     2821 atcaagttta caaaggatgc gaatcacgca gagaaagtta aaagtctttc ttctaatact
     2881 tttggttggg gtataaagtt atttcttttg aaactctttg aacaagggat tgcaaaaatt
     2941 gaagcaactt ttgtcgaagc tcaaaaaaaa atatgggctg ttttacctga acattctttg
     3001 aagcaacgca ttggtaataa tctagctttg atttatagtg gagctctcct aattcaagat
     3061 atactgggct atcctttacg attagagcat atacagacgg tgcttattaa ttcgtacgaa
     3121 cagttaattg tagatactag tttaggaagt gagcaaacgg tatttgaccg agtgaaaacg
     3181 ttgttggtga tgaatagcca taaattttta acaaacagtg acaacaaaca tacgcccagt
     3241 acgatttggg gaaaagtatc aattcaaaaa aatggggata ttaaggtaaa tatttttcct
     3301 atcccgtttg aggacttgtt aaggcgagaa tttcaagtaa aggatctaac ctatcttttt
     3361 agacaattgc ttgattcggg taatatgtgt gcagaaaaag ggagaagaac gaaacgtatt
     3421 cacatgaatc gtcaagttct tccaacatac gagattctat taccttcttc actcaaatcg
     3481 tattttcgat tgtaatttag aataaaccaa agtatgaaag tgaggcacca tgttatggaa
     3541 atatttctta ttgatttagc aaaacaactg attacttatc tgtatgatga cgagcaaacc
     3601 caaacggaag taaatgaagc ttgatctatg cttcatttac ttcattcaat caaacattta
     3661 agaaagggga attctaatga ctaaaaataa aatgacacta aaagcagagg ttcttctgta
     3721 tattcaagaa catttttcta atcaagcctt ttttacaaaa ccaatttact tggctttcga
     3781 aataagaggg gtatctgctg gatctattgg aggtactctt caagcgttga agaacgaagg
     3841 atatttagaa aatcactttg tgcaacgttc gttcaatgga agagtcgcga aagaatggta
     3901 tttagttcat tcatagagag gtgattcaag catgcgtgtg gcttgttatg atcgaacgtc
     3961 tgtttatgaa gaagcgaaaa tcagtaatga cgctcaatat gatgcagtga aagagtatgt
     4021 tttagagaaa tatgaacaaa ttcctcaacg attttcagac aaaggagaat caggtggaaa
     4081 agcggatcgt ccagcttttc gacagcttag agcttgggtt tgtgcgtcag aagaagaggg
     4141 ggtgatctat gtctggcgtt atgatcgatt ggcacgtcaa gccaaaatag ccttagaatt
     4201 tattgagttg tgccaacaac atcaggttca agtttattcg atttctgaac ctcttcctgc
     4261 ttctttctcg cacgcgtcaa cgaataaact atttgtgcaa ttattgttca cttttgcaga
     4321 acaacaacga aacgtcatta ttgaaaatgt tcgtgccgga cttgcctata aaaagcaaca
     4381 acggcaatat ttgtcttctg cggttccata tgggtatcgt ttagtgaatg ggaaaatcca
     4441 acaagaagca catgaagcaa aagttgtccg ccatatcttt caactttatt tgactaaaaa
     4501 atatggctac aaaaagcttt gtcaacgatt gacgcaacaa aagttcttct tccgtgaacg
     4561 tccttttcag ccctatcata tttatagtat cctaaaaaat ccattgtact atggcgaaat
     4621 caaaggagga tctttgggga agtatctagg aacctttgaa ccgattctct cgaaaacaat
     4681 ctttttacaa gcccaagaga ttcgccaatc aaggtgtaca gctaaaaaag atacgtatcc
     4741 gtacttatta cgtcaaaaaa ttcggtgtcc cttctgtggt cgtcatctga gttcgaagta
     4801 tcaatggaat acaaagaaga cgaagacgct tcattattat cattgtaccg accgaagctg
     4861 ccaaggaatc tttcttcggg cagaaagggt tgagtcagaa gtattggaaa agatacaggc
     4921 tttttttcaa tacgaaggcg tctatcaagc cttgattgcc caattgacgc aacaattagc
     4981 cgaaaagcga aaagatgaaa aacacaaagt aatccaacaa aagaaacaag aagcacaatg
     5041 gctcaaggca tttgaagagg gcaattgttc actggaagaa ctcaagcaac agctgcaagc
     5101 tcttcaaaag ccgaggtcta cttcttcgtt tctttcactc caacagtgtg aagcaaaagt
     5161 gaaagaatgg cttcaactaa aagacctctc tagtcgacaa ttgttatgtg accatgtttg
     5221 tcggatcgag gtaacaaagg aaaaaacagt ctgtgggatt tacttccgac aaatgacaca
     5281 aaatatttta gaagggaacg aatgatctat ggaaacgaca ccaaccaaac gagtcgcatt
     5341 gtatattcgg gtgagtaccc aagaacaagc tttagaagga catagtattc aagcacaaga
     5401 acaaaatgga cgacagtttg ccgaacggat gagctatgaa gtggtagaag tttatgccga
     5461 tgaagggatt agtgggaaat ccacaaaaaa tcggttcgcc tatcaacgaa tgatgaacga
     5521 tgctcggaac catcgttttg atctactagt gatttggaaa ttgacccgtc tcggacgcaa
     5581 tatgttagat gtcttacaaa ccgtcgagga actgttgcga tatgatgtgg ggttacattc
     5641 gatctcggaa caatttgacg tgactacttc gacaggaaaa ctaatgttac aactccttgg
     5701 gagtttcggt gaatttgaac gcaaccaaat tgcggagaat gttcagatgt caatgcaaag
     5761 cttagtgaaa gataaaaagc gttatgcagg tggacgacgt ttaggctatg tcagtggtat
     5821 tgacacgaat ggtcaaaaac aattggtcat tgaaccagaa gaggcgaaaa ttgttcgtct
     5881 gatctatgca aaatatttag gcggagcagg gtatcgagcg attgccaatt ttttgaatcg
     5941 tcaaggatat caaacagtca aaaagaatgc tttttctacc acggcagtca aagatatctt
     6001 acgcaataaa atttatgcag ggtatttaga atatgcacgc tatatcaatt gggaaaccaa
     6061 acgacgaaag ggcaagaacc caaaaccgat tttagtgaaa ggtacccatg aaccgattat
     6121 ttcggaagaa gattatcaaa aagtgcaaga acgccttgtt ttagaaggca aacagcccaa
     6181 atggaaccat acaggtgaaa atgtattgac aggcttgtta cgttgtccag aatgtggggc
     6241 accgatggca gcgagtaatg tcacaaatac tctaaaggat ggcacaaaga aacgaattcg
     6301 gtattattct tgttcagtct ttcggaataa aggagcaagt gtgtgtcatg ccaattcgat
     6361 tcgtgccgaa caagcggaaa catttgtcgc cgaccgatta aaggagatcg ttcagctacc
     6421 agaagttctt ccccgattgg tggcagcgtt aaatgaagaa atagtgcgac aaagccaacc
     6481 attggaacaa gaactcgtgg tgttactgga acgaaaggaa gaattgaaga ctaaaattga
     6541 aaaatgggaa gctgctttgg aagatagtcc tgaattgttt ccgatgttaa aagaccgctt
     6601 agacgaattg actgaaaaac gacgacagtt gcacattcga gaaaatgaaa tcttagggat
     6661 ctttcaacaa caaggagagc cgattcaagt caaagatgtc caacggatat tgactagttt
     6721 ggatcgtttt cttgcccaga gtgagaagaa gcaagtcaaa gccttgtatc gtacctttat
     6781 tgagaaaata acctttgatc ctaactataa ggagatattg gagattacaa tgaaattcac
     6841 gcctgccgtg gtacaacaat tgaatgagca atatcaaata gccgtatcca aaacaaagga
     6901 tacggctatt tttgtgttaa agacaccctt tacgttaacg atctagtcta ggttatatca
     6961 aacaacgtta gaggggcgct aacgcttctc tagcgatttg aaatcgttag atgagtcgtt
     7021 agggaggtcc ttatcataaa tagggatatt tattaatgaa tatttgaaat ataattgtat
     7081 ataagaatta aaaagagtgg ggatagatat gaaaaagatg ggtaagtgta ttttatgtga
     7141 aaaatacact gaacttacta aagaacatgt accacctaaa aaatcaggga atactggagg
     7201 taaaaagacc agaactggta atttagatga tttccttaag agcgatttta caaaaggtga
     7261 ttttccgaag gggattaaaa ggaaacctca aggaaatgtt tattatacgt tatgtagtaa
     7321 atgtaatagt ttttttggta gtgagtatgt tgaggaatat attagatttg cagaagacaa
     7381 taaaaatttc ctttataaca atacaagttt aaagaatggt aagtctgatt taacacattc
     7441 aataaagaaa atgaattcac ttagagttgc aaaagcaatt gtagcaatgt tttttagttt
     7501 aaatggggat gaagattcaa tggataagcc attcttagat tcggtacgag aatatcttag
     7561 caatcctaaa agtactttat ttcctcatga agactacaaa attataatga attattatct
     7621 tccaataggt gctccacaga attctaaaat caaaattcct aatgacattg taaatgatgg
     7681 tgacactcac aatgtaataa aaggttttat gccccttgat ctatcaactg ggagaaaaat
     7741 tcgattttca gaaattcagt atgaaggaat tggttttact cttatagatt taaaaaattc
     7801 aacttttgaa ataaaagaag gattagattt aaaaaatctc ctttgtgcag atgataaaat
     7861 caaaaaaata caattgtaca aagtccctat attaacacca acagtactta caatgttgga
     7921 gatggaaaat aatattaatt atattgactc aggttcagat ttgctgatta ggtggcaggt
     7981 aataactaat tttcttatgg aattaaaaaa atacagtaat actcaaacga agttctcttg
     8041 aagttataaa gaatacaata aatataaatt tcctttagac tatattaaaa tcagcaatcg
     8101 aaggaaaata aacgaagaaa atggtacgca aaatctaact attagagcaa aaacaggaag
     8161 ctgctttgga agatagtccc gaattgtttc cgatgttaaa agatcgttta aatgaattga
     8221 ctgaaaaacg aagacagtta caaattcgag agaatgaaat cttagggatc tttcaacaac
     8281 aaggggaacc gattcaagtc aaagatgtcc aacagatatt gactagtttg gattgctttc
     8341 ttatccagag tgagaagaag caagttaaag ctttgtatca cacctttatt gagaaaatca
     8401 cctttgatcc taatcagaag tagatattgc cgatcccgat gagattcaca cctactgtga
     8461 tttgataatt gaatgagtaa tatcaaatag ccgtatccaa accaaaggat atggctattt
     8521 ttgtgttagg gatatacgtc acgtagcttg ttatcaagaa taagtttctt tatttttttg
     8581 ctttttctaa aactgagtat gctaaaataa gagggtatat agcaacttta aataagagat
     8641 aggagtgtat ctttttgggt gcagaattaa atcagaagtt atttagtgcg gcagataatc
     8701 tccgtagtaa aatggatgcg tcagaatata aaaattattt attggggctg attttctata
     8761 aatatttatc cgaccgtttg ttggaacaag tggttctttt agcagatgaa tccttagagg
     8821 aatatgacac agtaagcaaa caaacgatgt tgtatcgtga attactttca gatgaagaat
     8881 caaaagaaga tctgattgca acaatcgttg atattttggg gtatgcgatt tcgccagagt
     8941 atcttttcaa cgtcttagcg gatcaagcaa aacaagcaac gttccaattg aatgatctaa
     9001 acaaagcctt tttagcaagt catatttatg gaaaaatact gtcggcaaaa ttcgaatagt
     9061 gtcgaggagg tgctgtgatg gaagaattaa aagaacgcat tgtcaattat gtcatagaga
     9121 actctgagat taaaaataaa tgggggaaca atacagcaca gaaaatatct gaaaaattaa
     9181 atgttagtcg taatattgtc tctcaatatt tgaatgaatt cgtaaaagat ggagaatttg
     9241 gaaaaatcaa tactcgtcca gtaatcttct tttctttacc ggagaaagtt ccaaatcaac
     9301 aaatttttag ctcttcagag gaagcggaaa aatggtatga tagctctttt agggttggaa
     9361 tagaaagggt tatcggaagt caaggaagtc tgcgaaatgt aattgctcaa attaaagcag
     9421 caatctacta tccgccaaat ggcttaccca ttttacttca tggcgagact ggaactggaa
     9481 aaagctattt agcaaattat gtgtataagg atttgttggc caataattat atagaagaga
     9541 aggcatcttt catttcagtt aattgtagtg aatatgccaa taatccagaa cttttcttgt
     9601 ccaatttttt tgggcatgta aaaggtgcat atacaggagc cgaagatgga agaaagggtt
     9661 tagcagaatt agctaataat ggagtcttat ttttagatga aattcatgca ttgagcaatg
     9721 aatgtcagga gaaacttttt cagtttatgg atacgaggaa atttcatcgg atgggtgata
     9781 atgaaaactg gtacacatca agttgctgga ttatatttgc aacatcagaa ccacctgagg
     9841 ataaactatt atcaactttg ttgagaagaa tacctgtaaa gctaacactt ccaacattag
     9901 acagtcgttc tctttatgaa agaaaacagt taatcaagat attttttaaa tcagaagaag
     9961 aaagactagc aaagaaaata ctgatatctc aacaattatt agatttttta ttaaactatc
    10021 gctttagtga aaatgttggc aatttgaaaa atatcattca attgacctgt gccaatgcct
    10081 tttatttctt agatgatttg gaagaacttt atattcagat gtatcattta ccacaatggg
    10141 tgaatttcaa cggcatgaag gttatgaaaa gacagaatga attaaaatat attcaaatgg
    10201 atgatttgga aaaagtagac gaagttttta atatcaacga acttatagag tatctttatc
    10261 aaacgtggaa gaaagacact gataagcagc agctttttga gaaatatgat agatatttta
    10321 gacaaaagaa tgttgatatc caaaataatt cagctttaac atatcccacc tatcaagaga
    10381 ttcgatttag acagtatgtt aaggaaatag agagagattt tcaaatagaa tttgactatt
    10441 attatcttca aataacgtct atctttttga attcttggat ttatcaaatc caattaacat
    10501 cggacgataa attatattcc ttcatcaatg atattaatag ttggtgtagt cgagaagttc
    10561 aattagtcaa tcgttttatt caaatagggg atatttattt aacaaaaatt caaaaaaatg
    10621 ttttggttat tttatttaag ttaatgtgta gtaaagaatt tcagcaaaaa cgtttagcac
    10681 tgattttggc tcatggagat ctaacggcaa cctgtatagc aagtactgct aataggatcg
    10741 ttgagagata tatatacgac gccattgata tgccactaat gacttcaagt agtgagattg
    10801 cagacaaaat taatagatac ttacaagagt gtaccggata tgaagaaatt attttacttg
    10861 ttgatatggg ttcactggag aaaatttatc taaatttgga actagacgct caaaaaaaat
    10921 tcggactact aaacaatgtt tcaacaagaa tggctattga tgttgcaaat cagatattat
    10981 tagatttacc gcttaaacag attcttgaac aagtaaaaga aaatcaaaat gtggattata
    11041 tttatgaatc atcaaatatt aagaaggata tgattgtctg ttcttgtgca agcggattag
    11101 gaacttcgtt taaattaaaa aagatacttg aagatagctt tccaagggat actgatcttg
    11161 tcatagaaac gtgtgactat tactctttag tgaatgaaaa ctatttatcg gagcttcgta
    11221 aagagaacaa tattcttttt attgttggaa cactaaatcc acatctagaa gat
//
LOCUS       DAZUJR010000090        11263 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.090, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000090 DAZUJR010000000
VERSION     DAZUJR010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11263
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.090"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            225..1484
                     /gene="lysA"
                     /locus_tag="ACG804_002398"
     CDS             225..1484
                     /gene="lysA"
                     /locus_tag="ACG804_002398"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HFS4833285.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            1471..2271
                     /gene="dapF"
                     /locus_tag="ACG804_002399"
     CDS             1471..2271
                     /gene="dapF"
                     /locus_tag="ACG804_002399"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HFS4833286.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            2274..3155
                     /gene="dapA"
                     /locus_tag="ACG804_002400"
     CDS             2274..3155
                     /gene="dapA"
                     /locus_tag="ACG804_002400"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HFS4833287.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            3152..3868
                     /gene="dapB"
                     /locus_tag="ACG804_002401"
     CDS             3152..3868
                     /gene="dapB"
                     /locus_tag="ACG804_002401"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HFS4833288.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            3874..4569
                     /gene="dapD"
                     /locus_tag="ACG804_002402"
     CDS             3874..4569
                     /gene="dapD"
                     /locus_tag="ACG804_002402"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HFS4833289.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            4585..5586
                     /locus_tag="ACG804_002403"
     CDS             4585..5586
                     /locus_tag="ACG804_002403"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HFS4833290.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            5583..6944
                     /locus_tag="ACG804_002404"
     CDS             5583..6944
                     /locus_tag="ACG804_002404"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HFS4833291.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            6904..8055
                     /locus_tag="ACG804_002405"
     CDS             6904..8055
                     /locus_tag="ACG804_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFS4833292.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            8030..9199
                     /locus_tag="ACG804_002406"
     CDS             8030..9199
                     /locus_tag="ACG804_002406"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFS4833293.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            9374..10753
                     /locus_tag="ACG804_002407"
     CDS             9374..10753
                     /locus_tag="ACG804_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFS4833294.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            11034..11263
                     /locus_tag="ACG804_002408"
                     /pseudo
     CDS             11034..11263
                     /locus_tag="ACG804_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3749 a         1958 c         2508 g         3048 t
ORIGIN      
        1 tcatcactaa atagtgttga atttatgttt ttatgtataa atagcttcta atagttcggg
       61 tattttgttt ttataaccat ttttattctt atttttaaaa aaatatttcg aaatatacta
      121 gacaattcag aaaattttgt ttaatattat tccaataaaa ttcaaatctt tatcaaatga
      181 aattccaata aaaacggaaa aaaagtgaaa agaggaatga aaaaatgaca gaattgataa
      241 ttggcggagt cacagcaagc acattggcag aaaagtataa gacacctctg tatgtgtatg
      301 atgaagaaaa gatgagacaa acgatgctgt cattcaagcg aggctttgta tcgaaacgtt
      361 ttgatacaaa agtgctttac gcctctaaag cattccaaac gattgagatg ctgcatttag
      421 ttcgtgaata tggattcggg ctagatgttg tcagtggtgg ggaaatctat accgctttgc
      481 aagctgattt tcctagagat actatctact tccatggtaa caacaagacg ccagaggaac
      541 tgatctatgc acttgaaaat gatttgttgc atattgttgc cgataatttg atggaagttg
      601 aattattagc agaattaagc caacgctatt taaaaaaaat ctgtatcatg cttcggttga
      661 atgtcggagt agaagcacat actcatgaat atatcgtcac tgcgcatatt gattcaaaat
      721 tcggcatgag ctatgaaagt aaagagtgcc aacaagccct tcagttgata aaagaaagca
      781 gctatctaga gttagaagga tttcatgctc atatcgggtc acaaattttt gatgttactg
      841 cttggttagc tgaaatcgac aaattgacga attacttaac cgattttgac caacctcttt
      901 ccttgaatct tggcggaggg tttgggattc gttatacaca aaatgatcag ccgatcccag
      961 tcgaagaggc actaaaaaaa ctgattgaat atacggaaga agctttggaa aaacgaaaac
     1021 tgaccattcg tcaattactg atcgaaccgg gtagaagtat tgttggagaa gctggtacaa
     1081 cactatacac gattggtttc atcaaaaaga caccacataa aaaatattac tttgtagatg
     1141 gcgggatgac agataatatc cgtccagctc tgtatcaggc agaatacgat tgtgatttag
     1201 cagcaaaact gtcggaagaa aaaacagaga aagtgacgat tgcaggaaaa atgtgtgaat
     1261 caggcgatgt ggtaattaaa gaagcttatt tgccgaaagc agaatcgggt gatcttttag
     1321 ctgtttattc cacgggagct tatggatact cgatgagcag caactacaat cgagcgacac
     1381 gaccagcagt tgtttttgtc aataatggcc aatcaagact gattgttcgc agacaagcat
     1441 tttctgatct actaaggggg gaagtttcct atgatccttc ataaatataa tggctgcgga
     1501 aatgatttta tcttattaga ttacgcagaa gacacagatt atagtcaatt agccgcttct
     1561 ttatgcacaa aagaaaaata tgatatagac ggattgatcg ccgtaaaaat cgatccgttg
     1621 gaaatgatct attacaacaa agatggcagc cgcgcgccga tgtgcggaaa tggcattcgc
     1681 tgttttgctc gatacgtaaa tgatcagaac atgatgaatg aacaggaatt caacgtagag
     1741 acattagcag gcacaagaaa aattacggtg ttggatccct caccttttta ttgcagcgta
     1801 gatatgggag tgccagatga ttctccggaa aaaatcaaag ctaatcaaac ttatccaata
     1861 aaaaaccagg aaatagagat caatggtgaa aaagtaacga tcactagttt atttttagga
     1921 acgattcata ccgttgtttt tgttgaaaat gcgcgtgagg aagtctggag aaaaagaggt
     1981 gaactgatct gtcatcatcc tttgttcaaa gaaaaaacca atgtcaactt tgtagaagta
     2041 gtcaatgaac aagaattgat cgtccgtacc tatgaaagag gagtaggttg gacacttgct
     2101 tgcggtacag gttgctgtgc ctcttatgtg gttgctaagg aaactgggaa aatttcagca
     2161 gatcaggtag ttgttcactt ggaacaagga gacttgatga tctctggtga ggatgcgata
     2221 caaatggctg gcccagcagt tcatgaatgg acaagaatat tggaggaatg aagatgataa
     2281 aaggttcgat cgtggcgctg atcacgccga tgaatgaaga gggatcagta gattatgctg
     2341 gtttggaaaa attgatccaa ttccatttag atgaacaaac agatggatta ttagttttag
     2401 gtacaacagg agaatcttct acgctcacac aatctgagga ggagcagatc cttcaactga
     2461 cagtaaagaa agtggctggc cgtgtgccgg tgattgcagg agctggaacg aataatacga
     2521 aagaaacgat tgaaaaagcg aagcattttg cttctttggg ggcagacgca cttttggtca
     2581 tcacccctta ctacaacaaa acaagtgatg caggactagc tgctcatttt acagcaattg
     2641 cagaagcctc accgattccg cttattttgt ataatgttcc ttctagaaca ggcatgtcga
     2701 ttccaatcca tgtattagta aatttagcag aacatcctaa tatcattggt ttgaaagaag
     2761 cctcaggaga tatggcttat gtgatggatg ccgctcggtt gattggagaa gaattcttcc
     2821 tttacagtgg aaatgatgat ttgatcctac cagtaatgag tgtaggagga agcggtgtaa
     2881 taagtgtatg ggcgaatatc caacctaaaa tagtccatga attagtaaaa gatacgcagg
     2941 acggaagatg gcagcaagca aaagaaaagc aattaaatgc acttgaactg atccatgcct
     3001 tgttcagtga gaccaatcct attcctgtca aagcagccat gtcattatta gacttacctt
     3061 ccggacctct acgcctgcct ttagtttctc tttcaaaaga gaaaaagaaa caattagctc
     3121 agcttttgtt aaaagaaagg acggttgaaa aatgaaaatc ggactgattg gcagtggaca
     3181 gatgggaaat agagtcgaag aagttgcaca agaaagagga gatacggtcc ttcttttacg
     3241 gacggcacct aaagaagcaa ctacgcttgc ttttacggaa ctgccagaac tgcttattga
     3301 tttttctcat ccagataatt tagagaaaat cctttcgtat agcttatcat atcaacttcc
     3361 gttagtcatt ggcacgacag gttatacaca atcacagttc caagaaataa aagaacatgc
     3421 caaacatgta cctgtgatgt atagtgctaa tttttcgttc ggcatcatgg tgatgaatca
     3481 actaatcaag caagcagctg caatgttgca aggctggcag atcgaactga ttgaaaaaca
     3541 tcatagtcgt aaaaaagatg caccatctgg tactgcaaat atgctgcttc aaacaatcca
     3601 agaagtgcaa aagctgcagc ccgtatacaa ctggcaaggg aaaaaaagag aagaaaacca
     3661 aattggtgta cacagtattc gtgcaggttc tttacctggt gaacatgatg tattgtttgc
     3721 tgctactgat gaaatattta cgatcaaaca tgaatctttt tctaatcgaa tctttgctgc
     3781 aggcgcagta gaagcagcgg actggttgaa agatcagtca ccaggttatt acaaattaga
     3841 agatttatta atggacaaag gggtgtaaaa aacgtggaag ctcaagaaat catccgctac
     3901 attcaaacgg catctaaaaa gacgcctgtg aaagtctatc tgaatgtaac cgagccaatc
     3961 gaatttaaag aaagtaaagt ttttggtgaa ggaagcagct tcgttgtttt tggtgactat
     4021 gagacgattg ctccggtttt agaagctgaa tcagaaaaaa tcattgaaat cgaaatcgaa
     4081 actgctgcaa gatacagcgc agttcctttg ctagatatta aaaaaattaa tgctcgtatc
     4141 gaaccaggtg ctattatcag agatcaagtg tcaatcggca acaatgccgt gatcatgatg
     4201 ggagcgatta tcaatattgg tgcagtaatc ggtgaaaaca cgatgattga tatgggtgct
     4261 gtcttaggtg gacgagcgac agtgggcaaa aactgccata ttggtgcagg agctgtctta
     4321 gcaggtgtga tcgaaccagc atcggccaaa ccggttatcg tagaagacgg cgtactggta
     4381 ggtgcgaatg cagtgattgt tgaaggtgtc catatcggaa aagatgcagt cgtggcagca
     4441 ggagcagtgg ttttagaaga tgtggcagca gaaactgttg tcggtggaat acctgcacgt
     4501 gtattaaaaa taagtgatga tcagacaaaa gaaaatacag cattgattgc tgcgttacgc
     4561 gaattataga ggagatggag aaaaatgcgc gaaatagata cctgtattgt gggggcaacc
     4621 ggattagtcg gccaaacgat gctcaaagtg ttagaagaat atgattttcc agtaggacga
     4681 ttgaaattat tagcttcaaa acgttcagcc ggtaaagttt gtgtattcaa gaaaaagaaa
     4741 cacactgtac aggaattgac agaaacttca tttgaaggat atgatttagc gctattttct
     4801 gcaggtgctt ctgtatccaa agagtttgcg ccaatcgcac gaagtcaggg actatttgtc
     4861 atagataatt cctcagcatg gcgggaagat tcggatattc cattaatcgt tccagaggtc
     4921 aatctggaag actatacatt gaatcggctg attgcaaatc caaattgttc aaccattcaa
     4981 gcggtacttc cgcttaaagc tttacaagaa gcctttggta tccagcgagt caattattcg
     5041 acctatcaag cagtttctgg ttccgggcaa aaaggcattg aagatcttca tcgtacgcaa
     5101 aatgacgagg aaccagtttt gtatccttat aatattagcc aaacggtgat tccggaaatc
     5161 gatcagcctt tggaaaatgg gtatacaaaa gaagaacaga aaatgataaa tgagacccgt
     5221 aagattctgc atcagcctgc tttgccagta tcagcaacct gcgtacgtgt gccaatcgaa
     5281 aatggacatg gagtctctgt ggcagttcaa ctgcaaaaag agtttacgac ggaagaaatt
     5341 agagagtgtc tcagccagtt tccagggatt caattagaag atgatctagc agcacataaa
     5401 tatccgacga gcattcttgc tagaggaaca gatatggttt atgttgggag gatcagaaaa
     5461 gacacttctt tagagaacgg attgttgttc tatacgactg ccgataacat acgcaaagga
     5521 gccgctgcga atgccgtaca gattgctgca gctttaatgc agaaaatagc ggaggtggca
     5581 agatgagtaa tacgctgaaa gtagcgaaat tcggcggaac atcgatgtct catgaagagc
     5641 aattcaaaaa agtccgtaca attgttcttt cagatcccaa tcgccaagtg atcgttgttt
     5701 ctgctttagg caaacgtacg tcagatgatg acaaagtaac agacttactt tatttgattt
     5761 atgcttacct tcagcatcat gttgattgga cacccctttg gaaaaggatt tgtgatcgtt
     5821 tcattcaagt aagagatgtt cttgccctgc agttacctat tgaagatgaa ctagcacgca
     5881 tacagaaaca actggaagac gaaaagataa ctgaagatta tttagtaagt agaggtgaat
     5941 atctgactgc tcaactgatg gctgagtatc ttggttacca gtttattgac gcaaaagacc
     6001 tgattttctt tgactatgat gggaaaatcg atcaggaaaa aacagcacag gaaatcacaa
     6061 aagcatttaa aagatatccg aaaatggttg ttccagggtt ttacggggcg aaccctgcag
     6121 gaaaagaaaa attattgggc cgtgggggaa gcgacattac cggcgcgata ctggcgaaga
     6181 tgttgcaagc ggaaagttat gagaattgga cggatgtttc aggaatcatg atggctgatc
     6241 cgcgaatcat cgatcatcct aaaatcatcg aggaaatctc ttttagagaa ctgagagaga
     6301 tggcttatat gggggctaac gttcttcatg aagcagctgt tttcccagtt caagaggctg
     6361 atatccccat ccaaataaaa aataccaatg atcctttcgc tcaagggaca aaaatatcga
     6421 atcacgaaat agaaaaggaa aatggactga caggaatagc tggacgcaag gattttcttt
     6481 ccatcacttt attcaaacgt catatgtccg atgaaatcgg gtttatctgg aaagcaatga
     6541 gcatttttgc taaacatgag atatcaatcg aacatattcc ttcagggatc gacaatatcg
     6601 gagtgatcgt ctcagcagaa gcgattgccg ataagttatt tctcatcacg aaagaattaa
     6661 aagaaacact tggcgtggaa gaaatcgtcg tgatcgaaga cttagctttg atctctgtcg
     6721 ttgggggtcc gcataaagaa ttgattggat tatctgggaa agtgttatcg atattgaaca
     6781 aattagaaat tcgcacatcg atcttatcac aaggagcaca ggagttgaat ctgatcatcg
     6841 gtgtaccgaa taatcaatat gaaacagtag tgaagggtat ctatgaaggg atggtgaata
     6901 cggatgctga aagaatatcg aatggcactc catcaaattc ctgaaatcgg gtttcatgaa
     6961 ttcaagacaa aaaaatattt atatgaacaa gtaaaaaaca gcgaggccgt tatccatgaa
     7021 atcggcgaaa caggactact cctttatttt gataatcagc aagaagaaac gattgctttt
     7081 cgaacagata tcgatgcact gccagtcaaa gaagaaacga atctctcttt tgcttctaag
     7141 catgaaggtt atatgcatgc atgtggtcat gacggacata tggcgatgct tttagggttg
     7201 actgacttta taactaaaca cattgaggat cttatttata atgtagtact gatctatcag
     7261 ccatcagaag aaatttccgg tggcgcacaa agcgttattc agtcaggatt gttggataaa
     7321 tatgaagtac aagcaatatt tggctttcat ctatggcctg gactagctaa gggagaagtt
     7381 ttctctcgac caggaccttt gatggcacaa agcagtgaaa cagacattat cattaaaggc
     7441 cagtctgcac atattgcttc tagtgaaaaa ggaatcgata gtctggaggc agctgtacga
     7501 tttttgaaga atgtttatga ttttgaccgg caattaccgg cagagtggaa tcatctaatg
     7561 aaatttggcc aaatccaagg tggaacgatc cgaaatgttt tagctggaga agttattgta
     7621 tccggaagta tccgttctta cagttcagat atgcaaaatt atttgaagag gggattagac
     7681 catttagcag aacagtttca ctctacagct actatttctt ttcgctataa tgacggctat
     7741 ccagctgtaa tcaaccatag aggcttatat gcagcactgt tagattcaaa caaactacat
     7801 gaattagatg ctccagttct tcaagccgaa gattttggca tatatacgca acaatatcca
     7861 tgtgtatttt tctttttagg tgtcggtgat acccctgctt tacatgatcc gacgttcgat
     7921 tttgatatgg atgttttaga aaatggtgta gaatggtaca aaacgattct ttttacagaa
     7981 aatcttcttg taaaaatcga tagcagttca aaagaggagc gagtaaataa tgatgaattt
     8041 atccaatcga tttagtccta ggctttctag aatagaagta tcaaaaatac gacaattcga
     8101 tcagcaaata tcgtcgatac cagatgtgat caaactcacc ctgggagaac cggattttcc
     8161 aactcctgaa catgtcaagc aagcaggaat agcagcgatt gaagaagact tttctcacta
     8221 taccggaatg agaggattag aggaactgcg ggaagcggct tgtatatttc agcaacagcg
     8281 ttatggatta acttatgatc cgcaaacgga agttttgacg acagttggtg caacggaagc
     8341 gattgcctct gcgttgttat ctgttttgga agaaggagac aaggttctta ttccagcgcc
     8401 tgcttattca ggatatcagc cattagtgga actagctggt gctgaattga tcccgataga
     8461 tacttctgac acagggtttg tctgtcagcc ggaacaattt gaacgagcat ttgaacaata
     8521 tggatcagct gtcaaagcag tcattttaaa ctatcctaac aatcctactg ggacgacatt
     8581 gtctgcaaaa caattgaaag caatcgctga ggttttaaaa aaatatccgg tatttgttat
     8641 aagtgatgaa gtatatgctg aattgactta tagtggaacg catatgtcca tagctactta
     8701 tcttccagaa caaacaatcg tgataagcgg gttatccaag tcacatgcga tgactggttg
     8761 gcgagtgggc tttatttttg ctcaaaaagc ccttattgac gaactaatta aagtccatca
     8821 atatctggtg actgccgcta caacgatgtc gcaaaaagct gcggctgaag cgctaataaa
     8881 tggggtgaaa gatagcgaga atatgaaaga gcaatatcaa acacgaagag actatctggt
     8941 ccagcaattg gcgcctttag gatttgaagt gacccagcca aacggtgcat tttacttgtt
     9001 ttgcaaactc ccagctgcca ttcaaactga ctcttggcag ttttgtgtag aattagcgga
     9061 acaggcaaaa gttgcgtgta tcccaggaat tgcatttggc ccagaaggag aaggttatat
     9121 ccggatttct tatgctagca gcatggaaaa attacatgag gcctgcaaac ggatcaaaga
     9181 ctttttaaca gaacagtgat tcatagattt tatcaaaaaa acaatcgtta attttgcggt
     9241 atattctgca aggagacgat tgttttttaa atttagttca aatgaacgcg tttcttttga
     9301 ttcataacta atgtaatgtt aagtttaaat tgtttagaat gattttaaaa gaatattcaa
     9361 ggaggtttca tcaatggaaa aaatcaaagt tgtcattgta ggtgcatctc atggagggca
     9421 tcaatcgatc ttggaactat tgacacgata cggtgaaaat gtagatatca cgctatttga
     9481 agcaggagac tatatttcct tcatgtcatg tggtatggag ctgtatttag aagacaaggt
     9541 aacagatgta aatgatgtac gtaatttcag accagaaaac tttccgcaat ccaatgttca
     9601 tattttaaat aatcacgaag taaaaacgat cgatgccgat aaaaaaacag taacggttac
     9661 tagcgcatca gataacgaaa caaaagaata tccttatgac aaattgattt tgagttctgg
     9721 tgtcaaacca aacaatctgc cagtaccagg agcagatcta gaaaatgtct acttgatgcg
     9781 tggatacaat tgggcaacca aaatcaaaga aaaattaaat gatccggcta ttaaaaaaat
     9841 cgctgtcgta ggtgcgggtt acattgggat cgaagcagca gaagcaagcc gaaaagctgg
     9901 gaaagaagtc gtattgcttg atgtgatcga tagaccttta ggcacttatt tagatgctga
     9961 gatgacagat attttagaac aacacctaaa tgaaaacggt attgaagttt tgacaaatgc
    10021 aaaaatcgaa gcttttactg gtaacggaaa agttgaggca atcaaaacaa gtgaaaaaga
    10081 aatcccagca gatctagtca ttcaagctgc cggtgtgaag gcaaatacag aatggttaaa
    10141 agggatcgtc gacttagatg aacgtggctg gatccaaaca aatgaatact tgcaaacgaa
    10201 tcttccagat gtgtatgcag taggagatgc tacacttgct tattctatcc cagcacgcaa
    10261 aaaaatgccg atcgctttag cgactgttgc acgtagagaa gcacgttatg tagtaaaaca
    10321 tctttttgaa gaagtaccaa acaaaccgtt cggcggagtc gtaggttcct ctgcattaag
    10381 tgtctttgac tatcattttg cagcaagcgg attgaatagc tttacagcag caaaagcagg
    10441 agtagatgta cgagtgtctt attatgaaga tacgttacga ccaaaatatg taccagaaga
    10501 acaaggaaat ccaaaagtgt ccatccaatt attctcggat ccaatgaccc atcaattgct
    10561 aggaggagca gtattatcta cctatgatgt tacaggtcaa ggaaatgtat tggcactagc
    10621 gatccaaaac aaactgactt tagaagaact agcagaagct gacttcttct tccagccagg
    10681 ctttgaccga caatggagca tgttgaatct agccgctcaa caagcgttag gagaagaacc
    10741 atttgtagaa taagaaaacg aaatatttga aaagaggttg tgaaaaagct gccttgcatc
    10801 aagtaataag aacagccaag taaaaacagc ttcttatgtt tttaacttgg ctggacttat
    10861 taccgcagat gcaagctttt gaacaccgtt tattttcaaa aaagggactg tgacacgatt
    10921 tgtgtaccga cccccaaaag ttagaccaaa aaatctaact tttggaggtc ggtatttttt
    10981 atggttaaat atacttttga acttaaatta aagatcgttc atgattattt ggatggcaaa
    11041 ggcgattgga ccgtaaaaat ccagatcaag agattgaagc ggaaatgctt aaaattcggg
    11101 agaagcacaa ggattatggc tgtttacgga tgaccaatga actaagaaac cgcggtttct
    11161 ctatcaataa aaagaaagtt cagcgcttga tcaagaagct aggaataaaa gtaacggcat
    11221 acacgcgtaa atcacgtcgc tacaattctt atcgaggaaa agt
//
LOCUS       DAZUJR010000091        11154 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.091, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000091 DAZUJR010000000
VERSION     DAZUJR010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11154
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.091"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(367..1158)
                     /gene="msrA"
                     /locus_tag="ACG804_002409"
     CDS             complement(367..1158)
                     /gene="msrA"
                     /locus_tag="ACG804_002409"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFS4833295.1"
                     /translation="MLDVEQMEIDLYNIILNRNTREWERTQFEEAKEDLAKMSIKQVI
                     EKLEVNLRPLALRDNLTPDAMDFYLRITGESASAKAYDYAKHKITSPLYQERAIFAGG
                     CFWCMVEPFETKPGVISVLSGYTGGETKKPNYDQVSGGYTGHVEAVEIIFDTRQITYE
                     ELLEIYWQISDPTDAFGQFQDRGKQYRSILFVVNEKQRQLAEKSREQLIQSNRFSRPI
                     VTEIRQAKTFWPAENHHQQFYQKQPKRYKKIKHSHQLHLFFQRHR"
     gene            complement(1349..1984)
                     /locus_tag="ACG804_002410"
     CDS             complement(1349..1984)
                     /locus_tag="ACG804_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HFS4833296.1"
                     /translation="MIFLQKYGFYFLLLGVISDLSTPYILGLFYPKLNQMTTVISVFG
                     DVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFIGTSKTLAILAVATVGLYGIGDCIFT
                     GLFSINTNESSWNLSTWIHNIGSGLGYAGFLLFPLLLVLLYRQSGQGTLSHFYLVLTV
                     ISLLIAGLYGLARIPSISQFAFFKQLGFFQRLSFFFNYLPMICLSFFQLRK"
     gene            complement(2250..3302)
                     /locus_tag="ACG804_002411"
     CDS             complement(2250..3302)
                     /locus_tag="ACG804_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFS4833297.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
     gene            complement(3315..4253)
                     /locus_tag="ACG804_002412"
     CDS             complement(3315..4253)
                     /locus_tag="ACG804_002412"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HFS4833298.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
     gene            complement(4704..5354)
                     /locus_tag="ACG804_002413"
     CDS             complement(4704..5354)
                     /locus_tag="ACG804_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833299.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNTNHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
     gene            complement(5454..5963)
                     /locus_tag="ACG804_002414"
     CDS             complement(5454..5963)
                     /locus_tag="ACG804_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HFS4833300.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILDVFAEAEIYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
     gene            complement(6164..7033)
                     /gene="scrK"
                     /locus_tag="ACG804_002415"
     CDS             complement(6164..7033)
                     /gene="scrK"
                     /locus_tag="ACG804_002415"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HFS4833301.1"
                     /translation="MYGSIEAGGTKFVCAIGNDDLKVLERVSFPTTTPNETMSLVIDF
                     FNHYKEQLESIGVGSFGPIDIHRESKTYGHITSTPKTAWKNFDFVGTLNKHFEIPIAW
                     TTDVNAACYGEYVSGHGKGLSSVVYYTVGTGIGGGAIQDGIFVEGFSHPEMGHTLVKR
                     HSGDTFSGTCPFHHDCLEGLASGPAIEMRTGTKGQDLSIEDPFWEIEADYIAQCACNT
                     TLMLSPDIIIFGGGVMQQEHLKKKVQRRFLELINGYVDTPNIEEYIVTPKLADNAGTI
                     GCLTLAKDVRINS"
     gene            complement(7053..8174)
                     /locus_tag="ACG804_002416"
     CDS             complement(7053..8174)
                     /locus_tag="ACG804_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 172 protein"
                     /protein_id="HFS4833302.1"
                     /translation="MNCLNNIWLHKGEESRTISPENKNGEKGKAAMTASHLGIGRKGS
                     PSVPINAGETITLAEMEGPGILRHFWMTVTDKTIAGSFVLRDLILRIYWDDESTPSVE
                     SPLGDFFCNGFGTRCEVNSLPIVVNPTSGMNCYFEMPFRKKAKITLTNEHPEFIKHIF
                     YTFNYALTEVPDDAMYFHAKWNREPITTKGKDYTLIDGIKGTGYYVGTYFALCALERY
                     WWGEGEFKFYIDGDEDFPTITSTGAEDYFGGAWAFHKKNFGERAYAQNFNTLFMGYPF
                     QSKRDHTRDYFSAGKPNPNPVHGFGDDALPMHGLYRWHLPDPISFKENLRVTFQTLGN
                     DDIKLYERQDDISSVAYWYQKEPHEFFEKLLDREERIPR"
     gene            complement(8176..8571)
                     /locus_tag="ACG804_002417"
     CDS             complement(8176..8571)
                     /locus_tag="ACG804_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFS4833303.1"
                     /translation="MRRLIIASHSILAEGFKETLEFLTGMHNQISSLCAYVEEIDDID
                     EQIKELVDTTDEIIVLTDMAGGSVNQKFFTYISDRVHVIAGMNLPLAMSIALQLGNDN
                     LDIGAIIAEAQQQIIYMNNQKSEERIEDE"
     gene            complement(8590..9387)
                     /locus_tag="ACG804_002418"
     CDS             complement(8590..9387)
                     /locus_tag="ACG804_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFS4833304.1"
                     /translation="MSEKYQVTKKDLRKANYRWLMSVCTFNYQTQQGASVTYALSPIL
                     RKLYKDDDEYIEALNNHFQYYNTQPWLAAIILGACVAMEEKQGLEAKDAINDFKVGTM
                     GPIAGIGDSLLMTMIPTIMGSIAAYMALENNPVGIFLWFILIMVIFFFRMRGFEFGYK
                     QGMKIVTEYGEKINYLTEAASVLGLTVVGSLIASVISVSTPLKFTFGEVSMKIQPMLD
                     KILPTLIPVIITAAAYYLLSKKKISMTILILLVIVFAMVMAAFGILA"
     gene            complement(9389..10177)
                     /locus_tag="ACG804_002419"
     CDS             complement(9389..10177)
                     /locus_tag="ACG804_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFS4833305.1"
                     /translation="MHFTIFQIIMLTILAFIKHVDYYGIPMIFVNYAVFWGLFTGILM
                     GDIKTGLIVGGTVQLMSLGVAGFGGSSVPDYGTCAIIATAFGSQLGVEAGLAIGLPVG
                     MLGVQLDVIVKILNGFVVRKSQEYANKREFKKMNSVLWLGPIFFGLSAAIPVFIAVTL
                     GQSAVNYVLDVLPNWFMDGLTLAGKMLPAVGIAMLLRFMPTGRYISYLLVGFFLAAFL
                     KVPIIGAAIIGFALAFNVYHRAEKDAQITASAGASDVGFIGEDE"
     gene            complement(10191..10667)
                     /locus_tag="ACG804_002420"
     CDS             complement(10191..10667)
                     /locus_tag="ACG804_002420"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFS4833306.1"
                     /translation="MSIVMSRVDNRLLHGIIVTQWAPMSKANRVMVIDDSVANNDIQK
                     SSMRLARPAGMAVSIITEETAIANFKKGKYDQEKVFVIVKEPETILHLVDNGIRIDRL
                     IVGGTVVKDNALQLSSRAYASDENISTYKKLLDSGVEIVTQFVPADKAQEIQSKLG"
     gene            complement(10739..>11154)
                     /locus_tag="ACG804_002421"
     CDS             complement(10739..>11154)
                     /locus_tag="ACG804_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFS4833307.1"
                     /translation="KFSNQLNRHFNDNELKVLNNNILKNFSLTNLMEQLTILNPTKLL
                     ERVSDAIYILQNDLGISFDNNTCFGLYVHISCLIERLVKQNTLEDEIYFNETSEEFQK
                     FQTHFKQSFSVVEHYYSVDIPIHEVKYVYDYVKRA"
BASE COUNT         3528 a         2373 c         1633 g         3620 t
ORIGIN      
        1 tatagttatt gtttgcgctt ttatacggaa tttagttcat cattaatgtg gaattcgatt
       61 aggtgtctat taattatcaa gatgattctc tacaaaattc catagaaaaa tcaagattct
      121 acaattcgaa ttctctttca catggaaata aaggctagta aaaaaacagg agttgtgaca
      181 aaagacttgt catacctcct gtttccttgc gacttgaagc tgaatgcttt gcgccacaac
      241 cttttcctcg gtgttctcaa agcaactcct cgaaataatt cataactgtc caaaaatatg
      301 aaaagctatt tttgtcagtt gctcattatt ttgtcggagc tgaacgcttt gcgccacaac
      361 cttcctctat ctatgtcgct gaaaaaataa atgaagctga tgcgaatgct tgatcttttt
      421 atatctttta ggttgcttct gataaaattg ttgatgatga ttttcagctg gccaaaaagt
      481 ctttgcttgg cgaatctctg taacgatagg acggctaaat cggttagatt gaatcagttg
      541 ttctcttgat ttttcagcca attgcctttg cttttcatta acaacaaata gaattgaacg
      601 atattgtttc ccccgatctt gaaattgacc aaaggcatct gtagggtctg aaatttgcca
      661 ataaatctcc aacagctctt cataggttat ttgacgtgta tcaaatatga tctcaacagc
      721 ttcaacatgc ccagtatatc caccactgac ttgatcgtaa tttggttttt tggtctctcc
      781 acctgtataa ccagataaca ctgagattac acctggtttt gtttcaaaag gctcaaccat
      841 acaccagaaa cagccaccgg caaaaatcgc ccgttcttgg tataagggtg aagttatctt
      901 atgtttggca taatcataag cctttgcact cgctgactcc cctgtgattc ttaaataaaa
      961 atccatcgca tctggtgtca aattatctcg tagtgctagc ggacgcaagt tgacctctag
     1021 tttttctatc acctgcttta tcgacatttt tgctaggtct tcttttgcct cttcaaattg
     1081 tgttctttcc cattctcttg tatttcgatt taaaataata ttataaaggt ctatttccat
     1141 ctgctccaca tctaacatga agtcaccctc tttcaagttt tcttcttatt cattcaaaaa
     1201 atgactacct gaaatttagc acaacgcata acaagttaag actaacttgc ttttcgctct
     1261 cctcatctct attcttagtc gaacacatcc acacgaatgg ttacccatag agaaattctt
     1321 ttacttaatc agcttcacac tgctttttct actttcgtag ttgaaaaaaa cttaaacaaa
     1381 tcatcggcaa atagttaaag aaaaaactta agcgttgaaa gaagcccaat tgcttaaaga
     1441 aggcaaactg actaatcgac ggaatccgtg ctaatccgta aagacctgca attagtaaac
     1501 taataactgt taaaacaaga taaaaatggc taagcgtacc ttgaccactt tgacgataaa
     1561 gcagaacaag taacaatggg aaaagtagaa agcctgcata gcctagccca gaacctatat
     1621 tatggatcca agtcgataga ttccaagagc tttcattcgt attgatactg aataacccag
     1681 taaaaataca atcacctatc ccatataaac caactgttgc aacagcaagt attgcaagtg
     1741 tttttgatgt tccaataaat aggtgataca acgcaggcaa cgaaagaaca aaaaaaagtc
     1801 cagatacaac tgaccagacc aagaaagcac gtctgactgg actatctacg tcaccaaaca
     1861 cactaattac ggtagtcatt tgattcagtt tgggataaaa aaggccaagg atatacggtg
     1921 tcgataaatc actaatcaca cctaataata aaaaataaaa accatatttt tgcaaaaaaa
     1981 tcattttctt ctcctacttt ttagtgatta ttcgatacat ccaacaatca aattttttct
     2041 cattttaaca catattttta ttctagttgc cttttgaaca atcaataaca taaaggtgag
     2101 tttcttctac attttaaaaa atcgaatggc actgaagagt tcagttgtca gcatcaatct
     2161 cctactcaaa aaggcaaaaa aacgtaagtc agatgttgtt gacatctcac ttacgcatcc
     2221 attgattgaa aatttcttag taaaatctac tagcctaaaa atttgaagac ttcttctcga
     2281 tcatacagtt taaatacttt ctcgcataaa aattgagtaa ttagtgccgc aaaaacaggg
     2341 atgactaacc aacaaagaac aacaagaaag ccatttagcc ctgcatctaa agaagccaac
     2401 ggaccaacaa gtccgaccac gccgaaacca gcagaagcag gcgtacctga aatagaaaat
     2461 agagcgacag gaatagctgt aatcactgca ctaactaaac aaggaataag aatcacaggt
     2521 tttctaaata gattaggcat catcatcttc atagcgccta aagcaatcgc aattgtcaca
     2581 cctgacttat taaccttcca agagttcact actaaaacaa aagtggttgc agctacgccc
     2641 atcgcagccg caccagcaga aacaccatct agttggattg ccattccgat tgctactgtt
     2701 gaaataggag agataatcaa aaaggcaaag gaacaaccaa tcaagataga cattaacagc
     2761 ggttgtaagg tagtgaagtt attaatcaat gatccaattg cagaagtaat tgctgttaca
     2821 aaagggaata aataaaaacc aagtaaacct gcacctacac ctacaacaat cggtgttaac
     2881 acaatcgaca ctgacccaaa actatttcca atcagtaaaa tcagcccgac agcaatcgat
     2941 gctgtcagca tcgtattaat aatatcgcct gtaccagcac caacgtaaac acccgtttca
     3001 cccaaatcag gtgtgaattt gactacacca gaaccaacaa aagaagctcc ggctacaacc
     3061 atcattctca tcggatcaaa tccaaattgt aaggcaatca aaccaccaat gatcaaaggt
     3121 gttgctagtt gaaaaataac tgctaactgt gcgatcgtta ccgcaaaggg atacgcacta
     3181 aaatatttta aaatggcacc taatactgca ttaggaatca atccaataat gattcctgtt
     3241 gctgtaccag cgaggacttt attcagaaaa attttcggtg atattttttg tgaagtttcc
     3301 attcaatctc tcctttattt tacgttcaaa ctatcttctt ttgcatggac aagctcagtc
     3361 aagaaatcac aataaggcgt cgcaacacca tatttcttcc cttttctaga aattgcgcca
     3421 ttgatataat cgatttctgt taatcgatgg ttcttaatca agtcttgata cattgaagga
     3481 taatgtaacc caattgtttc cgggtcaaaa caagattcac aatgtgcaat gacttctggg
     3541 acatctagtt caatcttctc tactgctgct actttggcaa actcattgac aatcgtcgcc
     3601 accattttat gagcagtcga tgtttttcct agctcagcca tattaacgtc taagattgtg
     3661 catagtccgt tcattgttcc gttcacacat gctttgcgat aaatagaata gtgaatattg
     3721 tcagaaaaat gagcatttaa tcctgattca gacaatttgt ctgctaattt ttttgcagct
     3781 gcttcttttc catcacctaa attttgtaat tctactgaac cacttccaaa taatttgacc
     3841 tgaccaggac cttcaagacc tgccgtccac atggtatttc caatatagat attttccatt
     3901 ggtacaaatt tctcaataat atcttcatgc ccgataccat ttaatagaca taagacctct
     3961 gtatcttttt tgattaatga ttggatatcc tgcagcattt tttccagctg catcgctttg
     4021 gtaaatagaa taatcagatc aacttgatct tctttttcta cttcggattg aagaacgatt
     4081 ggtagttttg cttctacctc tttaccatta aaatttgctt gtaatccatg ctctttgatt
     4141 tgttggacat gttctgccca gccatcgatt aataatactt cgttcccact ttggtgaagc
     4201 attaacccaa agcgacttcc cattgcgcca gcgcctgcaa ttgctatttt cattgattct
     4261 tcctcctttt tctttctatt atattcattt gagaatcatt tcacaacctt gttttgttat
     4321 tcttctctta tttatcatgt ttatatccac cattcaagtt attttatcag caaatcaata
     4381 aaaactggaa tagaatccca atttcatcgt aagagaaact agactagcaa taagaaaata
     4441 gaaacattca tagaaaaaac ctcactcctc tgattataaa agagggggca ttaacctcgt
     4501 gtatactaaa accttccatt cattcgatgg atgattttct ttttgtgaaa aaatattcat
     4561 tgtagtacga tgttgcgcaa cacagacgga tggtattgct tattatttat taaaatcgaa
     4621 caatacactt atttaaaaac ttctttccca gattttcttc catttttaca gttataacta
     4681 gtattatcat gaaaaatagc cttttattgt ctatgggaat aataatttaa aattggtact
     4741 tttttattaa ttagttcatc gcccaataat ctctccagtt tcttagcatc tcctgactca
     4801 accggaatta tccaagccca gtccaaataa ttttttaaaa tctcatcata ttttgcaaat
     4861 atttcattgc catattccgt ccttaaaatt atattttcag tgccagacaa gtgatttgta
     4921 ttgagttgat aaaaaagatc tccatctaaa aaaatatcat tagaagaaga tttccccaca
     4981 gtaatgacca ttccatcagc tctatgtgtt acatacaaat aattgtatga cctcatttca
     5041 cctaatgaat caattatttc ttgcccttta gctctaatat attgatctct attacctatc
     5101 tcactcttat ttaacaaaag ttttttcatg tcaaatttaa tcggctgttt tatttttgta
     5161 aattcgcttc tactactaat ccaatccgag attaattttt caacatgtcc cagagtaaac
     5221 tctgatttat tcgctaaata ctttttttgt tgtattaaag acatctttcc ccgaagctca
     5281 aaattgagcc tacatcgatt ctctatctct tcaaaaagca tcttatcttc atcattctta
     5341 tattcatcat tcataaaacc aatccagctc ctcgattaag ataatatttt aatctcatac
     5401 aaaaactagc tctcatcaaa acaaccattg ttttgatttc tcatgaaatt tctttatact
     5461 tttctccgat tataaattcc taaccccttg agaaaattac gcatatattt atctccgcaa
     5521 ggcttaaaat ttcgttggcc ttcttttctc aaaaatgccc cgatttcgcc ttttgatgga
     5581 tagatttctg cctcagcaaa aacgtctaaa atatcatcag tggtcataga caaggcgatt
     5641 tttaattttt ttagcaacac attgttgata tatttgattt ccttgctttt ttgcggcgtg
     5701 tctactatcg gcttatcttt ttgcggacca cgcgccaaga gaatcaggcc atttaggaat
     5761 gcgtcaaaaa cttggttgtt gatggttttt tcatacacat tattttctgc attatctttg
     5821 ttcttatcct gtactttggt cagtaccgcc tgagcttctt ctttagtcag tggtacaccg
     5881 cctagctcaa aagctttaat caaatccgta tctttcaaat caatcgcata acgcaatcgc
     5941 aataacctat cattgttatt catttgttcc tccgaagtat ttagtcttta ctttcttacg
     6001 tactttttgt cttgctaaga tttttaggat caatgataaa aaccgcatca cttatgataa
     6061 ggcgctgggt atcatgagtg aatgatattg ctgaatacaa atagtccgac cacattaagt
     6121 tgatcggact tcataagcat tttattgact aatacttttt tgcttaagaa ttgattctaa
     6181 catcttttgc taaagttaag catcctatag ttcctgcatt atctgctaac ttaggtgtga
     6241 caatgtattc ttcgatattt ggcgtatcga catagccgtt aattagttct aaaaaacgtc
     6301 tttgtacttt ctttttcaga tgttcttgtt gcatgacacc accaccaaaa attataatat
     6361 ctggtgaaag catcagggtc gtattacagg cacattgtgc aatataatcc gcctcgattt
     6421 cccagaacgg atcttctata gaaagatctt gtcccttggt tcccgtacgc atctcgatag
     6481 cgggtccaga tgccaaccct tcgagacaat catgatgaaa aggacaagta ccagagaaag
     6541 tatctcctga atgtctctta actaacgtat gccccatttc tggatggcta aacccttcaa
     6601 caaaaatccc atcttgtata gctcctccac caattccagt tccaacagtg taataaacaa
     6661 cactggataa accttttcca tgacctgaaa catactcccc gtaacaagca gcattcacat
     6721 cggttgtcca ggcaattgga atttcgaaat gcttattcaa cgttccaaca aaatcaaaat
     6781 ttttccaggc agtttttgga gtagaggtga tatgtccata ggtctttgat tcacgatgga
     6841 tatcaatcgg tccaaatgac cctactccaa tgctttctaa ttgttcttta tagtgattaa
     6901 agaaatcaat taccaaactc attgtttcat tcggtgtagt tgtaggaaaa ctcactcttt
     6961 ctaaaacctt taaatcatca ttgccaatgg cacaaacaaa tttagtccca cctgcttcta
     7021 ttgagccata catttcttac tccaccgtcc ttttatctag gaattcgttc ttccctgtct
     7081 aatagttttt cgaaaaactc atgtggttcc ttttggtacc aataggcaac agaagaaata
     7141 tcgtcttgac gctcataaag cttgatgtca tcatttccta gggtttggaa agtaacacgt
     7201 aaattttctt tgaaactaat ggggtcgggt aaatgccagc ggtacaaccc atgcatcggt
     7261 aaagcatcat cgccaaaacc atgaactgga tttggattag gttttccagc actaaaataa
     7321 tcccgggtgt gatctctttt agattgaaaa ggatagccca taaatagcgt attaaaattt
     7381 tgagcatatg ccctttctcc aaagttcttt ttatggaaag cccaagcgcc gccaaaataa
     7441 tcttctgctc ctgtagatgt tattgtaggg aaatcttcat ctccatctat ataaaactta
     7501 aattctcctt ccccccacca gtatctttcc aatgcgcaca aagcaaagta ggttcctaca
     7561 taatacccag tgcctttgat tccatcaata agggtgtaat cttttccttt tgtcgtgatg
     7621 ggttcacggt tccatttagc atgaaaatac atcgcatcat ccggtacttc agtcaatgca
     7681 taattaaatg tataaaaaat gtgcttaata aactcaggat gttcattcgt taaagtaatc
     7741 ttagcttttt ttcgaaatgg catctcaaaa tagcaattca tccctgatgt tggattcact
     7801 acgattggta aggaattcac ttcgcatctt gtcccaaacc cattacaaaa aaaatctcct
     7861 aatggacttt ctacagaagg agtggattca tcatcccaat aaatacgcaa aattaaatca
     7921 cgtaagacga aactcccagc gattgttttg tctgtcactg tcatccaaaa atgacgtaaa
     7981 attccagggc cttccatttc tgctaaagta attgtctctc cagcatttat cggaacagaa
     8041 ggtgaccctt ttctcccaat tcctagatga ctcgctgtca ttgccgcttt ccctttttca
     8101 ccatttttat tttctggtga aatagttcta ctttcctctc ccttgtggag ccatatatta
     8161 tttaaacaat tcattttatt cgtcctctat cctttcttca cttttttgat tattcatata
     8221 gatgatttgt tgttgtgcct ccgcaataat tgctccaata tctaaattat catttcctaa
     8281 ctgcaaagcg attgacattg ccaagggaag attcattcct gcaattacgt gcactctgtc
     8341 agaaatatag gtaaaaaact tttgatttac acttcctcca gccatgtcag ttaaaacaat
     8401 tatttcgtct gtagtatcca ctaactcttt aatttgttca tctatatcat caatttcttc
     8461 gacatatgca cataagctac taatttgatt atgcatacct gttaaaaact ctagtgtctc
     8521 tttaaaaccc tcagctagta ttgaatggct agcaatgatc aatcttctca taattcaaat
     8581 ccttttcctt tacgctaata ttccaaatgc agccataacc atcgcaaaaa caataacgag
     8641 tagaatcaaa atggtcatac tgattttttt cttactgagt agataatatg ctgcagcagt
     8701 aataattact ggaattaatg ttggtaaaat tttgtccaac attggttgga ttttcatact
     8761 aacttcacca aaagtgaatt taagtggcgt tgaaacactg ataactgaag caattaatga
     8821 tccaactact gttagcccca atactgaagc agcttcagtt aaataattaa tcttttcacc
     8881 gtattcagta acaatcttca ttccctgctt ataaccaaat tcaaagcctc tcattcggaa
     8941 aaagaagatt accatgatta aaatgaacca taaaaagatt cctacaggat tattttctaa
     9001 agccatataa gccgcaattg atcccatgat ggttgggatc atcgtcatca aaagagagtc
     9061 cccaatacca gcaattggac ccatcgtacc aactttaaag tcattaatcg catcttttgc
     9121 ttctaatcct tgcttttcct ccattgcaac acaagcacct aaaataatgg ctgccagcca
     9181 aggctgtgta ttgtaatact gaaagtgatt atttaaagct tcgatgtatt catcatcatc
     9241 tttgtataat tttcttaaaa taggtgacaa tgcgtaagtc acagatgcac cttgctgtgt
     9301 ttgataatta aaggtacaaa ctgacatcaa ccaacgatag ttcgctttcc taagatcctt
     9361 tttcgttact tgatattttt cgctcatttt attcatcctc cccaataaac ccaacatcag
     9421 aagctcccgc agaagcagtg atttgtgcat ctttttcagc tctatgatac acattaaatg
     9481 ctaaagcgaa tcctatgatc gccgctccaa taataggtac cttcaaaaaa gcggctaaga
     9541 aaaatccaac aagtaaataa ctaatgtatc gacctgtagg cataaagcgt aacaacatcg
     9601 caataccaac agcaggcaac atttttccgg ctaatgttag cccatccata aaccaattag
     9661 gtaaaacatc caaaacgtaa ttaacagcag actgtcctaa agtaacggca ataaatactg
     9721 gaattgctgc agataaacca aagaaaattg gccccaacca caaaacacta ttcattttct
     9781 taaattctcg tttattcgca tattcctgtg atttgcgaac aacaaaacca tttaagattt
     9841 tgacaattac atctagttgc acccctaaca tacctacagg tagtcctatt gctaatccgg
     9901 cttctactcc aagctggcta ccaaatgccg ttgcaataat tgcgcacgtt ccatagtccg
     9961 gtacagatga gccaccaaaa ccggcaactc ctaatgacat caattgaact gtaccgccaa
    10021 ctatcaaacc tgtttttata tcacccatca aaattcctgt gaataatccc caaaaaactg
    10081 cgtaatttac aaagatcatc ggaatcccat aataatcaac atgtttaata aatgctaata
    10141 tagtcagcat aataatttga aaaatagtaa aatgcattat ccttactcct ttatcctaat
    10201 tttgattgaa tttcctgtgc cttatccgcc ggaacaaatt gtgtaacaat ttctacacca
    10261 gaatccaaca attttttata cgtgctgata ttttcatctg atgcataggc tctagaagat
    10321 agctgtaatg cattatcttt aacaacagta ccgccaacaa ttagtcggtc aattctaata
    10381 ccgttatcta ctaaatgaag gattgtttcc ggctctttca cgatgacaaa tactttttcc
    10441 tgatcgtatt tccccttttt aaaattcgca atcgctgttt cttcagtgat aattgataca
    10501 gccattccag caggtctagc taaacgcata cttgattttt ggatgtcgtt atttgcgaca
    10561 gaatcatcga tcaccatcac tctgtttgct ttagacattg gtgcccattg cgtgacaata
    10621 atcccatgca ataaacggtt atcaactctc gacataacaa tactcataaa tacttcctcc
    10681 tttatctttc attttcttac aagcaattac catgccaaaa caaaaagaac ttgataaatc
    10741 aagctctttt tacataatca taaacgtatt taacctcatg aatcgggatg tcgacactat
    10801 aataatgttc aacgacactg aaagattgct taaaatgtgt ctgaaatttt tgaaattcct
    10861 cactcgtttc attgaaataa atttcatctt ccaaagtatt ttgttttact aatcgttcaa
    10921 ttaagcaact aatgtgaaca tataatccga aacacgtatt attatcaaat gaaattccta
    10981 gatcattttg taagatgtat atagcatctg aaacccgttc taataattta gtcggattta
    11041 atatggtcaa ttgctccatt aaattcgtta gactaaaatt cttcagaata ttattgttca
    11101 aaactttcag ttcattatca ttaaagtgtc tattcaattg attggagaat ttac
//
LOCUS       DAZUJR010000092        11094 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.092, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000092 DAZUJR010000000
VERSION     DAZUJR010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11094
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.092"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            33..656
                     /locus_tag="ACG804_002422"
     CDS             33..656
                     /locus_tag="ACG804_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833308.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1106..2155
                     /gene="trpX"
                     /locus_tag="ACG804_002423"
     CDS             1106..2155
                     /gene="trpX"
                     /locus_tag="ACG804_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HFS4833309.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2152..3033
                     /locus_tag="ACG804_002424"
     CDS             2152..3033
                     /locus_tag="ACG804_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4833310.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3036..3806
                     /locus_tag="ACG804_002425"
     CDS             3036..3806
                     /locus_tag="ACG804_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4833311.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4085..4939
                     /gene="aroE"
                     /locus_tag="ACG804_002426"
     CDS             4085..4939
                     /gene="aroE"
                     /locus_tag="ACG804_002426"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0019632 - shikimate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HFS4833312.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5117..6280
                     /locus_tag="ACG804_002427"
     CDS             5117..6280
                     /locus_tag="ACG804_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFS4833313.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6397..6807
                     /locus_tag="ACG804_002428"
     CDS             6397..6807
                     /locus_tag="ACG804_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFS4833314.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6981..9209
                     /gene="topB"
                     /locus_tag="ACG804_002429"
     CDS             6981..9209
                     /gene="topB"
                     /locus_tag="ACG804_002429"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFS4833315.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9380..9664
                     /locus_tag="ACG804_002430"
     CDS             9380..9664
                     /locus_tag="ACG804_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833316.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            9824..10060
                     /locus_tag="ACG804_002431"
     CDS             9824..10060
                     /locus_tag="ACG804_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFS4833317.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10057..10455
                     /locus_tag="ACG804_002432"
     CDS             10057..10455
                     /locus_tag="ACG804_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HFS4833318.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
BASE COUNT         3876 a         1834 c         2304 g         3080 t
ORIGIN      
        1 aataaaaaat aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat
       61 cgagagtaca agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt
      121 attttcgacg tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt
      181 tattgccgga aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa
      241 ccagcaaatt gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg
      301 cgatatcggt gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt
      361 ttaatgatcc tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt
      421 atgatgtaca tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt
      481 tctttgatgg aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt
      541 ttgataagga gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag
      601 aagaagaatt ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca
      661 ttggcgcgat gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg
      721 tttgatcttc aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt
      781 cgattagact taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt
      841 atttcagcag aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg
      901 agactttccc atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga
      961 catgaacatt gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga
     1021 ccgctttggc cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa
     1081 agattgactt tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat
     1141 tattttagtt tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag
     1201 tacttcgacg aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca
     1261 tccggcatta gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa
     1321 agaaggagaa aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc
     1381 cacaatgagt caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc
     1441 tgccgctcaa tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac
     1501 ggatcctgtg ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg
     1561 tgtttctgat cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa
     1621 tgcaaaaaaa gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc
     1681 acaagcagaa gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc
     1741 cactaatgag attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt
     1801 tccattagat aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc
     1861 aaatatcccc gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat
     1921 cgggatcaat caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag
     1981 tggaaaagaa aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat
     2041 caatcaatct caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc
     2101 caaaatcatt acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta
     2161 tcagctattt cacaaggcat gctttgggca atattaggat tagggatttt catgacttat
     2221 cggatcttag actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc
     2281 tgtgtgacag ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt
     2341 gctggcatga tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt
     2401 attttagcag ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga
     2461 acaccaaatc tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg
     2521 ttacctgatt actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct
     2581 gtactgctat tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac
     2641 gaaacgatgg ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact
     2701 ttgtcgaacg gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca
     2761 gatgtaaata aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa
     2821 gtgatcttcc aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc
     2881 atttatcagc tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag
     2941 ttgttctccg ctatcatctt agctatttgt ctgatgatcc cgcaattgaa gaaagcactg
     3001 aacttaaaaa cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa
     3061 atggcagaaa agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta
     3121 accttacaat cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa
     3181 gcacactgtt caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta
     3241 aagatcagct gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt
     3301 tccaagaccc caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg
     3361 cacaaaaaag aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag
     3421 attttttcag actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag
     3481 cgggtgaatt atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag
     3541 ctcctgagtt actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag
     3601 cattaatgcg attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca
     3661 cgcatcgaat ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga
     3721 aaatcgttca agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc
     3781 agttctttga agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact
     3841 tgaaaactca ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa
     3901 catatttggg tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt
     3961 ctttgctctg acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc
     4021 gtactttttc gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa
     4081 taagatgatt tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag
     4141 tttatcccca ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt
     4201 agctttccaa gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga
     4261 tatgttaggt gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga
     4321 ggtaagccag gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg
     4381 tttgattggc tataataccg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat
     4441 ttcgatcaaa aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac
     4501 tgttcaagct gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac
     4561 attcgctcaa gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa
     4621 agttcgtgac tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct
     4681 agtcaatgca acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat
     4741 aagcatgatg catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg
     4801 tttattaaaa gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat
     4861 ctaccaagga gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat
     4921 tgaaaagctg tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg
     4981 gtctcaagaa aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat
     5041 tatcaaaaaa tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa
     5101 acgaggagga accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa
     5161 acctctgaag cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat
     5221 ggaaaatgag gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt
     5281 gaaccaatac gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa
     5341 taaaaaattt ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc
     5401 gtggaaaaaa atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt
     5461 ttttattggt aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac
     5521 ctttcatggg caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac
     5581 acgcggagaa gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc
     5641 ccataagccg aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg
     5701 acaaaataag atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt
     5761 agtagaaaat tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga
     5821 aaaagtgatc gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa
     5881 tctggatggt gtagatatta aaaaaggggt ccagaagatg gatggacatg ttcttttgca
     5941 gtacgcacgt ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca
     6001 agtaatgaac gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta
     6061 tgcagctggt aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa
     6121 aaacctcttt tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga
     6181 cggttcgtgg aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca
     6241 aatgaatcaa tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag
     6301 aagctgcgca aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc
     6361 ttatggtaga tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa
     6421 aatgagtcgc gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt
     6481 atcaccacat acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa
     6541 aatctaatca cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg
     6601 ccagaaggaa ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca
     6661 agaaatgaag aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag
     6721 atgccactgg atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc
     6781 atcaactggc agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa
     6841 gcagcaaacg gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt
     6901 atcttttttt tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat
     6961 taagtaacgg aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa
     7021 aagcctatgc cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg
     7081 atccattgtt tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg
     7141 ttgctccagg agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt
     7201 tcccagaaac cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa
     7261 aacgagaatt gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg
     7321 aagccatcgc gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt
     7381 tacgtttatg gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc
     7441 aacctggaaa gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt
     7501 ggctgattgg aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg
     7561 atggcagttt ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc
     7621 aagaagaaat caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga
     7681 caaacaaagg gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag
     7741 agttaacgaa ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc
     7801 ttgaagttac gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt
     7861 tgcagacaaa gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc
     7921 aaggattgta cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag
     7981 aaaatgagca tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag
     8041 aagaagtaca gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc
     8101 aagaacatca tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc
     8161 tttccaaatt acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg
     8221 ctgcagatta tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaagctaa
     8281 aaagcatcgg aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa
     8341 aaaagaaaga agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac
     8401 tgaaaagtat ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca
     8461 cagcaatgaa aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag
     8521 aagtagaagg aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga
     8581 agcattacat cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt
     8641 gtaaggcagt agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag
     8701 ggtacttgag aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca
     8761 aaaaattcat cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt
     8821 cagatgagat tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag
     8881 gaagatgtcc aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct
     8941 tgaatccgga atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa
     9001 cgaatctcag agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg
     9061 gtaaaaaagg gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt
     9121 cttttccatg gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa
     9181 gaaaaaataa tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt
     9241 ccgaaaagtg agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa
     9301 cgttggggta ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca
     9361 ttcattttta aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct
     9421 aaagtatcct gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc
     9481 accaacgttg attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca
     9541 taaaacgaca agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc
     9601 ggctatgatc attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg
     9661 ttaagaatac gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt
     9721 tcgtaagaaa aagcaaaata aaagtatata cattgattaa aagtatatac ttggatataa
     9781 tgtacttact atagaatgag aatggtatag agggtggcga aatatgaaaa aaatgaaaaa
     9841 gtataaaatt agaaaatctg gcaatagcga tgtaacaact atcccaccag aagtaaaaga
     9901 attcatgggt gtgcagacag gtgacgcaat cagttatgtt tttcaatctg atggttctgt
     9961 acgaatgatc aaagcacaag aagaacctga tattgattca ttagttgatt cgatcatgaa
    10021 tcaatatgaa gacgcgttaa aagatttggt tgatttatga ggtatctttc gactaaagaa
    10081 attatcaaaa tcaacgcgaa agttatttta cgtcactcgc caggcgaaat gatcggtgta
    10141 aaagatgcaa atgcattaga tatggccgtc aaacagcctt cacaagcagt attcaatcaa
    10201 gaactctatc ctgaaatcta tgaaaaagcg gcgattttag caattaattt agctaaaaaa
    10261 catccttttc ataatggcaa taaacgaact gctcttgttg ccatgttgtt gtttcttcaa
    10321 ttgaataatt gtccagttgc tttttctcgt caagaagctg ttgattttat cataatgatt
    10381 accactagtt cattggattt cgattcacta aagtccaaga taaccagtta tttacgacaa
    10441 accgcaataa aatgaacgaa ttaaaaactt tatttctcaa ttagatcagc atgtcattaa
    10501 ggaatatgct gattttttta tgtttaatca tacaaaatag ttttttcata aaaatatgga
    10561 aaatatggat taattttgaa ataattgatt taaaaggaat acaaaagagt gaatagtagg
    10621 aaatagtggt ttagaactag tgggctgatt ttttatatat tttagtttac ataatatata
    10681 ttatacaaag tagatttaaa aaatgataaa cctctctcga acggtttttt atcaaaaatc
    10741 gtcatttttc catcaaaatc tgcttatgca aaattataaa aaaattttgc agtttttctt
    10801 actttttttg tcgtttaatt gaatgataaa aaccagtttc tttattcagt taatcaaata
    10861 tgaacgaatt agatatgaat cattgtattt gccgttgcgg aaggattttt taattaacca
    10921 cagataaaca ttgataacga ttcgcttatt gtaatcaaca gattaaattt catatgttca
    10981 tatgtacgga tacattttcg gaccgattaa ttttaaccat tctatttatt tgcttaccta
    11041 ttagatatca ataaaaaact gcttaacagc tatttcagct gttaagcagt ttta
//
LOCUS       DAZUJR010000093        10463 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.093, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000093 DAZUJR010000000
VERSION     DAZUJR010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10463
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.093"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(47..871)
                     /gene="iolB"
                     /locus_tag="ACG804_002433"
     CDS             complement(47..871)
                     /gene="iolB"
                     /locus_tag="ACG804_002433"
                     /EC_number="5.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0019310 - inositol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-deoxy-glucuronate isomerase"
                     /protein_id="HFS4833319.1"
                     /translation="MEKTLKHQPLNKELAPGVKQIQNIRQSNSALSYIEFQILELEKG
                     ASYKETGSQQEVCIVILTGKIKVKAADTWYEDLGTRESVFEKIPTDSIYLPAEHSFEL
                     VATTDNVRLALCYSPAKKALPISVIRAEDNTVEERGLYQNKRLVHNILPDNVDTASSL
                     LVVEVYTEGGNFSSYPPHKHDQENLPHESFLEETYYHELDPEQGFVFQRVYTEDRSLD
                     ETMTVEHQNVVEVPKGYHPVGVPDGYTSYYLNVMAGPERIWKFHNEKKHEWILQRK"
     gene            complement(910..2826)
                     /gene="iolD"
                     /locus_tag="ACG804_002434"
     CDS             complement(910..2826)
                     /gene="iolD"
                     /locus_tag="ACG804_002434"
                     /EC_number="3.7.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002397168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016823 - hydrolase activity, acting on
                     acid carbon-carbon bonds, in ketonic substances [Evidence
                     IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019310 - inositol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3D-(3,5/4)-trihydroxycyclohexane-1,2-dione
                     acylhydrolase (decyclizing)"
                     /protein_id="HFS4833320.1"
                     /translation="MEKTVCLTTAQALLKFLNQQYISIDGKETPYVEGIFHVYGHGNV
                     LGIGQALELEPGHLKSYSGKNEQGMAHAATAFARQNLRKKIFAVSTSVGPGAANLLTA
                     AGTAFANNIPVLFLPADTFATRQPDPVLQQLEHASSVAFSTNDAFQAVSRYWDRINRP
                     EQLMSALLRAFEVMTNPATMGPATICLPQDVEAEAYAYPEEFFKKRVHYIDRRIPTAR
                     ELAEASQRIKASKRPVIIVGGGCKYSEAGEILEQISRDCQIPLVETHAGKSTVSWDFK
                     NNLGGMGILGTSAANKAVQQADLIIGIGTRYTDFTSASKSIFNFEQAKMMNINVSRQQ
                     AAKLEAFQVVGDAKATLEQLAPMIEGYQTAYGEKIDELKEEWISERNRLKAAHFKRKD
                     FTPEIKDHFSQEILNEYADALATNLTQTEVFIHLNDFVDEDAIVIGSAGSLPGDMQRL
                     WNPVKENTYHLEYGYSCMGYEIAGAMGVRMARPEQEVYALVGDGSFLMLHSELVSSLQ
                     YDKKINIVLFDNSGFGCINNLQMDNGGASQGTEFRNTKDEIMNIDYAKVAEGYGAKTY
                     RVSSIAELQAAVEDAKKQTRSTLIEIKVLPKTMTEGYDGSWWNVGISEVSGKAAMQEA
                     YKAKQAKLATIRKY"
     gene            complement(2837..3871)
                     /gene="iolC"
                     /locus_tag="ACG804_002435"
     CDS             complement(2837..3871)
                     /gene="iolC"
                     /locus_tag="ACG804_002435"
                     /EC_number="2.7.1.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047590 - 5-dehydro-2-deoxygluconokinase
                     activity [Evidence IEA];
                     GO_process: GO:0019310 - inositol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-2-deoxygluconokinase"
                     /protein_id="HFS4833321.1"
                     /translation="MSYIKFDQSKEFDLLLLGRVAIDFNPAYNDQVKEEFKPLKKVHM
                     FEKFVGGSPANIAVGVTKHGMKAGFIGTVSDDQFGEYVIDYFNEQGIDTSQISKAQHG
                     EKLGLTFTEMLSSKESNILMYRNQAADLQLSVEDIDEDYLKRSKALLISGTALAESPS
                     REAVIKAVMLAKRNNVKIIFDIDYRAYNWKNNDDISIYYSMIAKESDIIMGSREEFDL
                     TEKLIQPNMSDNESAAFWHSCGAEIVVIKHGMKGSTAYTADQQQFSIKPFPVEARKGF
                     GGGDGYGSGFLYGLFEGWEIIDCLEFGSAEASMMVKSNNCSDSLPTTQEVKDFITLEK
                     EIYGEMIARI"
     gene            complement(4028..5044)
                     /locus_tag="ACG804_002436"
     CDS             complement(4028..5044)
                     /locus_tag="ACG804_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016633586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4833322.1"
                     /translation="MAGTIKEIAEKAGVSRGTVDRALNDRGRINPEVAERIRAIAKEM
                     NYVPKKKKVIKETTLKLGIVTQLAKSSFMIPIRSGLESIIGDLKKRNIDCFLEEVDGV
                     DEAAQLQALDRLVELGVKGIAIMPVDSDGIREKINQLTDQGILIITFNSDILGTNRQC
                     FVGMDNFKSGKTAAGLLGMLTKGKGKVLAITGYFGNSVNSLRVAGFVEELKESFPELE
                     LTGVQSSFDSSAEVEKILSNTLENYSNLDGVVVFSGGQAGIARALEKIDESKRPFVII
                     YDLTKNNIEMLKNDQVDFLIDQDGFVQGYRSLLMLANQLQNNKTVTKDALFTDIIIKT
                     KYNI"
     gene            complement(5146..5298)
                     /locus_tag="ACG804_002437"
     CDS             complement(5146..5298)
                     /locus_tag="ACG804_002437"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833323.1"
                     /translation="MDVVKFLDDADIANDPNNPPQFTCEKCGKEMYPEYYRNALGIEF
                     KISDVQ"
     gene            complement(5315..6634)
                     /locus_tag="ACG804_002438"
     CDS             complement(5315..6634)
                     /locus_tag="ACG804_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016372324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS91 family transposase"
                     /protein_id="HFS4833324.1"
                     /translation="MKANILEAIFFDEHHNWDNFVEKYGRKIRLVVKREVNKFRYCGD
                     IQKGYRLFVCEGCHQTKFVPLKCRGKFCPTCATGESQRWSAVVANDMFKVTHRHVIFT
                     IDEGLREIFMMENYRDSLLKGLMDEAAKIILAYFEKRKVKAGIVATIHTFGSKLEFNP
                     HVHMVVTMGGLTRDGSWEEYDYLPFSMLRKYWKNAVLKLIRRTLGEWDKQRVQSRLQA
                     AYKNNGEGFYVNAPKRSRTNLKSLLQYISRYMKRGPIALSRILMYDGDTVMFNYMDKR
                     TNTKETMTMSIDEFIAALIRHIQNKNFKTIRRYGIYSRRIKTLMKKVMKEYQKRVKKL
                     FINLNEALRPKSWEERITEEFGENPLECSCCGEYYEFVGMSVRKNGRLVIKYAKDNHA
                     KRFMREENRKIDQKEFRQQYEEEKEKTFKAIRWDWERQREIYMSKLW"
     gene            complement(7012..7104)
                     /locus_tag="ACG804_002439"
     CDS             complement(7012..7104)
                     /locus_tag="ACG804_002439"
                     /inference="COORDINATES: protein motif:HMM:NF013677.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFS4833325.1"
                     /translation="MPRRSFDEIFKITAVKLVTEEGFSVKEVSL"
     gene            complement(7375..8355)
                     /locus_tag="ACG804_002440"
     CDS             complement(7375..8355)
                     /locus_tag="ACG804_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HFS4833326.1"
                     /translation="MLFLKKEDIIKSFSMREAIDADKKALSLYSAGKASVPLRTNIDV
                     PKSNGQSLYMPAYVEGGEGALGVKIVSVYPENIKKNLPSVPATMIVLDPETGMVSACL
                     DGTYLTQLRTGAVQGAATELLAREDAKIGALIGTGGQAQSQLEAMLTVRKLEEVRIFD
                     IDFERASQFAEKMMQQFSVTMRPTKTSQECVEGADIITSVTTSKRATFSAEWVKKGAH
                     INGVGAYTPEMCEIPREIIKAADVVIFDTMDGVLKEAGDFISPLQDGYIQRDSYHGEL
                     GQLINEELIGRTSGEQITIFKTVGSAVLDVVVATEIVKKAKENNLGKLIF"
     gene            complement(8368..9246)
                     /locus_tag="ACG804_002441"
     CDS             complement(8368..9246)
                     /locus_tag="ACG804_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HFS4833327.1"
                     /translation="MIRNILLTLIVAINLYFIIYFLRDLFKNKQNFKEEPGDMRLLPF
                     TSFIIFFLSTFGVSDFAIGTVLYPKLKWVSMKKLPGTLNTQCVVPVAVMALSYITAIN
                     VGIKTLAVCIICQIIGAYLGPRFVVKLPEKTIKLFVGIGLVIAALLIFAGQMNWIPSN
                     GTASELYGGKLILAGFLLFVYGALNNIGIGSYALTMVTVYLLGLNPVAAFPIMMGACT
                     FSVPIGSVQFIKFNEYSRKITLFTSTFGVLGVLVAVFLVKSLDTYILKWIVILVLLYS
                     AYTMLGSQLKKVTAAN"
     gene            complement(9262..10062)
                     /locus_tag="ACG804_002442"
     CDS             complement(9262..10062)
                     /locus_tag="ACG804_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HFS4833328.1"
                     /translation="METIIQIMKKYDFSEMETRVYTTLLEKGNLTGYEVSKISGVPRS
                     KVYNILEKLLKKNLIVVNKSEPKLYHAISANEFLEKLEKSVKNDLSFLTKNLGMIKEK
                     DEEEMLWKVDGIEYVLDKVEHLVKNAKESLLIQVWHENFTDSLLKALQQAEKRVDKFV
                     LILFSSTHEYDLPLEKYYIHGFETDKLADFGARWINIVADEQEVVFGTINEELQSTDV
                     TWTKNHAMVNLAKEYVKHDAYTLKVIAESPEELKAKYGEGFEGIRKIY"
BASE COUNT         2848 a         2403 c         1748 g         3464 t
ORIGIN      
        1 acctaactaa acctaactaa actttatgta tctaacagct taataactac ttgcgctgca
       61 agatccattc gtgtttcttt tcattgtgga atttccaaat tcgctcaggt cccgccatca
      121 catttaaata gtaggaagta tacccgtcag gtaccccaac tggatgatag cccttaggaa
      181 cttcgacgac attttgatgc tctaccgtca tcgtttcatc tagtgaacga tcttccgtgt
      241 agacccgctg gaaaacaaat ccctgctctg gatcaagctc atggtaataa gtttcctcta
      301 aaaaagactc atgtggcaga ttctcttgat cgtgcttatg aggaggatag ctggaaaaat
      361 taccgccctc ggtataaact tcgacgacca gcaggctgct ggcagtatcg acattatccg
      421 gtaaaatgtt gtgaacaagt cgtttattct gatagagtcc acgttcttcg acggtattat
      481 cctccgcgcg aatcacactt atcggcaaag cttttttcgc tggtgaatag caaagcgcca
      541 atcggacatt gtctgtagtt gccacaagtt caaacgaatg ctccgccgga agataaatac
      601 tgtcggttgg aattttttca aaaacagatt ctcgtgttcc taaatcttca taccaagtgt
      661 ctgctgcttt aaccttaatt tttccagtca aaatgacgat acagacctcc tgttgactgc
      721 cggtttcctt gtaagaagct cccttttcca gctccaaaat ctgaaattcg atataactca
      781 aagcagaatt agactgccga atattttgga tttgttttac tccaggtgcc agttctttgt
      841 ttaatggttg atgcttcaat gtcttttcca atcaatccac tccttatttt caatcacaaa
      901 aagcaatatt taatactttc tgatagtggc aagtttcgct tgtttggctt tgtaagcctc
      961 ctgcatggct gctttacccg atacctctga gataccgacg ttccaccagc tgccgtcgta
     1021 gccttctgtc atggttttag gaagtacctt tatctcaatc aacgtcgatc gcgtttgctt
     1081 cttcgcatcc tcgaccgctg cttgtaattc tgcaatcgag cttacacgat acgtttttgc
     1141 accatagcct tcagcaactt tggcgtaatc gatgttcatg atctcgtcct tggtatttct
     1201 gaattcggtt ccttggctag ctccgccatt atccatctgt aaattattga tacagccgaa
     1261 accagaatta tcgaaaagta caatgttgat ttttttatca tattgcaaac tagaaaccag
     1321 ctcgctatgc aacatcaaga aactgccatc gcctactaag gcatagacct cttgttctgg
     1381 tcgagccatt cttacgccca tcgcaccagc gatttcatag cccatacaag aataaccgta
     1441 ttccaaatga taggtattct ccttcacagg gttccataag cgctgcatat cccccggcaa
     1501 tgaaccggct gaaccgatca cgatcgcatc ctcatcaaca aaatcattta aatgaatgaa
     1561 gacctctgtt tgcgtcaaat tcgtagccaa cgcatcagca tattcattca agatttcttg
     1621 agaaaaatga tctttgattt ctggcgtaaa atctttacgc ttaaaatgcg cggcttttaa
     1681 ccgatttcgc tcactgatcc attcttcctt cagttcatcg atcttctcgc cataggcggt
     1741 ttggtaacct tcgatcattg gggcaagctg ctccaaggtc gctttcgcat caccaaccac
     1801 ttgaaaggct tccagcttag cggcctgttg tctgcttacg ttaatattca tcattttcgc
     1861 ttgttcaaaa ttaaaaatac ttttagaagc tgaggtaaaa tcagtgtagc gtgtgccgat
     1921 ccctatgatc agatccgctt gctgcacagc tttattagca gccgaagttc ccaaaatccc
     1981 cattccgccg agattgtttt taaaatccca cgaaacagtc gatttacctg cgtgcgtttc
     2041 aactagcgga atctgacaat ctcttgagat ttgctcaaga atctcaccag cctccgaata
     2101 tttgcagccg cctcctacga tgatgacagg tcgtttactg gcctttattc gttgactcgc
     2161 ttcagcaagc tcacgagcgg tcggaatcct gcgatcaata taatgtactc tttttttgaa
     2221 aaattcctcc ggataggcat aggcttctgc ctccacgtcc tgcggcaaac aaatcgttgc
     2281 cggacccatc gttgccgggt tcgtcatgac ttcaaaggcc cgcaataacg cggacatcaa
     2341 ctgctctggt cgattgatgc ggtcccagta gcgagaaacc gcttgaaatg catcatttgt
     2401 cgaaaaggct acactgcttg catgttccag ctgctgcaag accggatcag gctgacgtgt
     2461 agcaaacgta tccgccggta aaaaaagtac ggggatatta tttgcgaatg ccgtacccgc
     2521 tgctgttaac agattggccg cgcccggtcc aacagatgtt gatacggcaa aaattttctt
     2581 gcgtaaattc tgtctggcaa aggcagtagc cgcatgggcc attccctgct cattttttcc
     2641 gctataactt ttcaaatgtc cgggctctaa ttccagcgcc tgaccgatcc ccaaaacatt
     2701 tccgtgacca tagacatgaa agataccttc aacataaggc gtttctttgc cgtcgatgct
     2761 gatgtattgt tgattcaaaa attttagtaa tgcttgtgct gttgttaaac aaaccgtctt
     2821 ttccattttt ttcaccttaa atccgagcga tcatttcgcc gtatatttct ttctccaatg
     2881 taataaaatc ttttacctcc tgagtcgtcg gtaaagaatc tgaacagtta ttgcttttga
     2941 ccatcattga tgcttccgct gagccaaact ctaaacaatc gatgatctcc cagccttcga
     3001 ataaaccgta taagaaaccc gagccgtaac catctccgcc gccaaagcct ttgcgtgctt
     3061 ccaccggaaa cggcttgatt gaaaactgct gctgatcggc cgtataagca gtcgatcctt
     3121 tcattccatg tttgattacg acaatctcag caccacaact gtgccaaaaa gcagcgcttt
     3181 cattatctga catgttaggc tggatcaact tctcagttag atcgaactct tctcttgaac
     3241 ccatgataat gtctgattcc ttagcaatca tcgaatagta aattgaaata tcatcgttgt
     3301 tcttccagtt ataagcacgg taatcaatat caaaaataat tttgacatta ttccttttcg
     3361 ccagcatcac tgccttgatt acggcttctc tggacgggct ctctgctagt gcagttcctg
     3421 agattaatag tgcttttgac cgtttcaagt agtcctcatc aatatcctca acgctaagct
     3481 gcaggtctgc ggcttgattt cgatacatca aaatattact ttcctttgat gagagcattt
     3541 cggtaaaagt cagccccagc ttttcaccat gctgcgcttt gctgatctga gacgtatcga
     3601 tgccttgttc attgaaataa tcgatcacat attcgccaaa ctgatcgtcc gagactgttc
     3661 cgataaaacc agctttcatg ccatgtttag taacacccac agcaatattg gcaggagatc
     3721 cgcccacaaa tttttcaaac atatggacct ttttcaatgg tttaaactct tctttgactt
     3781 gatcattgta ggcaggatta aaatcaatag cgactcttcc taaaagcagc aagtcaaatt
     3841 cttttgattg gtcaaacttt atataactca atatatccac ctctttatcc gttcttctat
     3901 ttctgaggca agtatagcac gccaaaacaa agcgtgcaat atttatttta gaacgcaata
     3961 ttgcgtgctg tttgaaaatg acggcaaaaa aaacgtgaat cgccttacat cacgattcac
     4021 gcctagatta aatattgtat tttgtcttaa taattatatc agtaaatagc gcatcttttg
     4081 taaccgtttt attattttgc agctgattcg ctaacatcag taatgaacga tagccttgaa
     4141 caaatccatc ttgatcgatt agaaaatcaa cctgatcgtt tttcagcatc tcgatattgt
     4201 tcttagtcaa atcataaatg attacaaagg gccgcttgct ttcatcgatt ttttccaacg
     4261 ctcgggcaat tcccgcttgt ccgccagaaa agacgactac gccatctaag tttgaataat
     4321 tctccaaggt gttgcttaaa atcttttcaa cctcagcact cgaatcaaag ctgctctgaa
     4381 cacccgtcag ctccagttca ggaaacgact ctttcaattc ttcaacaaag cctgccaccc
     4441 gtaagctgtt gacgctattt ccaaagtagc cggtaatcgc tagaaccttg ccctttcctt
     4501 ttgtcagcat acctaacaat cccgcagccg tttttccgct tttgaagttg tccatcccaa
     4561 caaaacactg tcgattcgta ccaagaatat ccgaattaaa ggtaatgatg aggatgcctt
     4621 gatcggtcaa ttgattaatt ttttctctga taccatcact atctactggc atgatcgcga
     4681 tcccttttac tccaagctcc accaatcgat ccaacgcctg cagctgggcc gcttcatcga
     4741 ccccgtctac ctcttctaaa aaacaatcaa tgtttcgctt ttttaaatcc ccgataatag
     4801 attccagacc tgatcggatc ggaatcataa aagaagattt cgccaattga gtgacaatcc
     4861 ccagcttgag cgttgtctct tttatgacct tctttttctt tggaacatag ttcatttcct
     4921 tggcgattgc tctgattctt tctgcaacct caggattgat ccttcctcga tcgttcaatg
     4981 cccgatccac tgtccccctt gacactcctg ctttctcagc tatttcttta attgtacccg
     5041 ccatcttgcc tctccttttt tcctattgtg tttattttat cacaaaactt aagaaaacca
     5101 ccggagaatg aattctccgg tggacttttt gtatgattaa ccttcttatt gaacatcact
     5161 gatcttaaac tctattccaa gggcgtttct ataatattct ggatacatct ccttcccaca
     5221 tttttcacag gtaaattggg gaggattgtt cggatcattt gcaatatctg catcatctaa
     5281 aaattttact acatccattg ggattgattc tttttcacca caacttagac atataaattt
     5341 cacgttggcg ttcccaatcc cagcgaattg ctttaaaagt tttttctttt tcttcttcat
     5401 actgttgcct gaattctttt tggtcaattt ttcgattctc ctctcgcata aaccgctttg
     5461 catggttatc tttcgcatat ttaataacta accgtccatt tttgcgcaca ctcatcccaa
     5521 cgaattcata gtactcaccg caacaagaac attctaaggg attttcacca aattcttcgg
     5581 ttattctttc ttcccaggat tttggtctta aggcctcatt cagattgata aacagctttt
     5641 ttactcgttt ctgatactcc ttcatgacct ttttcattaa tgttttgatt ctacgactat
     5701 agattccata gcgacgaatc gttttgaaat tcttattttg aatatggcga atcagtgcag
     5761 ctatgaattc gtctatactc atggtcatcg tctctttagt attcgttcgt ttgtccatgt
     5821 agttgaacat gacagtgtcg ccatcataca ttaagattcg gcttaatgcg atcgggccac
     5881 gcttcatata acgactgatg tattggagta gtgactttag atttgtcctg ctccttttag
     5941 gagcatttac gtaaaaccct tctccattgt tcttgtacgc agcttgtaat cttgattgaa
     6001 ctctttgctt gtcccactca cctaacgttc gtctaattag tttcaataca gcatttttcc
     6061 agtattttct taacatagaa aaaggtaaat aatcgtattc ttcccaactt ccatctcttg
     6121 ttaagccacc catagtaaca accatatgaa catgcggatt aaattctagt tttgatccaa
     6181 aggtgtggat tgtagctact atacctgcct tcacctttct tttctcaaaa taggcaagaa
     6241 taatttttgc ggcttcatcc attagtcctt tcagtaagga atctcgatag ttttccatca
     6301 taaagatttc ccgtaacccc tcatcgatcg taaagattac gtgccgatgt gtcactttaa
     6361 acatatcatt cgccacaacc gctgaccacc tttggctttc acctgttgca cacgttggac
     6421 agaactttcc acgacatttc aagggaacaa actttgtttg atgacatccc tcgcagacaa
     6481 acagtcggta tcctttttga atatctccac aatatctaaa cttgtttact tcccgtttga
     6541 cgactagccg aatctttcgc ccgtatttct caacaaagtt atcccaatta tggtgttcgt
     6601 caaaaaagat tgcttcgaga atattcgctt tcatagtaat attttacttg ttcaaaaaca
     6661 aaatgaaaag ggctaaaaga ctggtagtgc agccttttta gcccttaact ttttatactt
     6721 tctttactgt ctaaaaaata tgcggcgcac agaacgcgcc gcatatcgga ctaagtttta
     6781 ttcaaatttg tcttcgccaa cacaatttga cgaagagcct tttctttcag gaagacttcg
     6841 gtaattttta ggagttctac ctattctttt aaccgtttat tctctttttc taagcgtgta
     6901 atttcatttc tgcgaatgga tttcatgact tcctctaccg agaaaagtac gttatccata
     6961 tttttcaact tcttgaactc atcaatacac gctattagag cgagcttcta gctatagact
     7021 aacttcttta acagaaaacc cttcttccgt taccagtttt acagcggtaa ttttaaatat
     7081 ttcatcaaat gaacgtcttg gcataatcca gatcttcgct ttctcttaat ttggtgtcaa
     7141 ttttagtata acccgtccaa cttatttttt aactaagtgc ccggtttttc ttgacaactc
     7201 cacccaaaag ttagattttt tggtctaagt tttagggtcg cttcattact agaattcaac
     7261 aagagatgtt ttttatttta tttaaattat ggggtcagtt tccatttgat tacaaacttc
     7321 tttgttttct ttttttaaac gcaataataa aggttttaat ttcagccttt ttaattagaa
     7381 aatcaatttt cccaaattat tttctttagc tttcttaacg atttctgtcg caactaccac
     7441 atctaataca gccgaaccaa ctgttttgaa gatcgtgatt tgttctccac ttgtccgacc
     7501 gatcaattct tcattgatca gttggcctag ttccccatga tagctgtctc tttgaatata
     7561 cccatcttgc agcggtgaaa tgaagtcccc agcttctttt agaacaccgt ccatggtatc
     7621 aaaaataaca acatctgcgg ctttgattat ttctcgtgga atttcacaca tttccggtgt
     7681 gtaagcaccg actccattga tgtgcgcacc ttttttgacc cactcagcag agaatgtcgc
     7741 acgttttgaa gtggtcacac ttgtaatgat gtctgctcct tcaacgcatt cttgactggt
     7801 ttttgttggg cgcatcgtta cagaaaattg ttgcatcatt ttttcagcaa attggctggc
     7861 acgctcaaaa tcaatatcaa aaatccgaac ttcttctaat ttacgaacgg tcaacattgc
     7921 ttctaattgt gactgtgctt gtccgccggt tccaatcagc gcgccaattt tagcatcttc
     7981 tcttgcaaga agttctgttg ctgctccttg aacagcgcct gttcttaatt gtgtcaaata
     8041 agtaccatcc aaacaagcgg ataccatacc cgtttctgga tccaatacga tcatcgttgc
     8101 tggtacactt ggtaagtttt tcttgatgtt ttcaggatac acggaaacga ttttgacacc
     8161 tagcgcgcct tcgccacctt ctacataagc aggcatatat aagctttgtc cgttgctttt
     8221 tggcacatcg atattggtgc gaagaggcac acttgccttt cctgctgaat acaatgacag
     8281 tgcttttttg tccgcatcga tggcttctct cattgaaaaa cttttgataa tatcttcttt
     8341 tttaagaaat aacatttgaa tcgctcctta attagctgct gtaacttttt ttaattgact
     8401 gcccaacatc gtatatgcac tgtatagtaa gaccaaaatc acgatccatt tcaggatata
     8461 ggtatctaaa gatttgacta ggaatacagc gaccaatacc cccaatacac cgaaggttga
     8521 agtaaaaagt gtgatttttc tgctgtattc attaaattta atgaattgaa cactgccgat
     8581 cggtactgag aaggtacaag cccccatcat aataggaaag gctgcaactg gattcaagcc
     8641 tagcaagtag acagttacca tcgttaacgc ataagaacca atgccgatat tgttcaatgc
     8701 accatagaca aagagtaaaa atcctgccaa gattaatttt ccgccataca attcactggc
     8761 tgttccgttt gatggaatcc agttcatttg tcctgcaaaa atcaacaatg cagcaatgac
     8821 caatcctatg ccgacaaaca gtttgatcgt tttctctggt aacttcacga caaatcttgg
     8881 tcctaaatat gcaccgataa tttggcagat aatacaaaca gctagtgtct tgatccctac
     8941 gttgatggca gtgatgtaag acaatgccat gacggctacc ggtactacac attgggtatt
     9001 caacgttccg ggtagttttt tcatgctgac ccatttcaac tttggataaa ggacggttcc
     9061 gatagcaaag tcggaaacgc caaatgttga aagaaagaag atgataaatg acgtgaaggg
     9121 caacagacgc atatcccctg gttcttcttt gaaattttgt ttgtttttga aaaggtctct
     9181 tagaaagtaa ataataaaat atagattgat tgcgacaatt agtgtcagca aaatattccg
     9241 aatcataaaa aattcctcct actagtaaat ctttctgatt ccctcaaagc cctcaccata
     9301 ttttgcttta agttcttcag gagattctgc aatcactttt agtgtatatg catcatgttt
     9361 gacatattct tttgctagat tgaccatggc gtggtttttt gtccaagtga catcggttga
     9421 ttgcagttct tcgttaatgg taccaaacac gacttcttgc tcatcggcga cgatgttgat
     9481 ccatcttgct ccaaagtcag caagtttgtc tgtttcaaaa ccatgaatat aatacttttc
     9541 taagggaaga tcatattcat gggtagaact gaataaaatc agtacaaact tatcaactct
     9601 tttttcagct tgctgcaatg cctttagtag tgaatccgtg aaattctcat gccaaacttg
     9661 aatgagcaaa ctttcttttg cgtttttcac caaatgctct actttatcca gaacatactc
     9721 gataccatca actttccaca gcatttcttc ttcatctttt tctttgatca tccctagatt
     9781 cttggtaaga aaagaaagat catttttaac acttttttct aatttctcta aaaactcatt
     9841 tgccgagatg gcatgataaa gtttaggttc tgatttatta acgacaatca aattcttttt
     9901 taatagtttt tccaaaatat tatatacttt cgagcgtggc acacctgaga ttttacttac
     9961 ttcatatcct gtaagattac ctttttctaa tagtgtggta tacactcttg tctccatctc
    10021 tgaaaaatca tattttttca tgatttgaat aatcgtttcc attgattaat cctcacttta
    10081 tttttagtag ctactacggt aacaactata aattcttttt gattatctgt caagagttag
    10141 ttcaataaca cacatataat aattagctta aaaacaatct ttttattaaa aagaaacatt
    10201 ataatatgaa tgtttgtgaa aaaataatac aacttagtca ttctttacaa cgatttatag
    10261 aaaaacaacc tctttaaata taaaaggtac gggttactga ttacttgtaa atctttacgt
    10321 tccagtttta ttctttctaa aaaatatact cacttctttt cttagacttc tttttttgat
    10381 tctcctcttt atggtcttgt ccttttttgc cttcaaaata tttaaataaa cccctttcaa
    10441 aagcatttct aggttttgga caa
//
LOCUS       DAZUJR010000094        10318 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.094, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000094 DAZUJR010000000
VERSION     DAZUJR010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10318
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.094"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(71..904)
                     /locus_tag="ACG804_002443"
     CDS             complement(71..904)
                     /locus_tag="ACG804_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HFS4833329.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(1208..3373)
                     /locus_tag="ACG804_002444"
     CDS             complement(1208..3373)
                     /locus_tag="ACG804_002444"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HFS4833330.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            3633..5927
                     /locus_tag="ACG804_002445"
     CDS             3633..5927
                     /locus_tag="ACG804_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HFS4833331.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            5920..6585
                     /gene="pgmB"
                     /locus_tag="ACG804_002446"
     CDS             5920..6585
                     /gene="pgmB"
                     /locus_tag="ACG804_002446"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFS4833332.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            6578..7585
                     /locus_tag="ACG804_002447"
     CDS             6578..7585
                     /locus_tag="ACG804_002447"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFS4833333.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            7607..8626
                     /locus_tag="ACG804_002448"
     CDS             7607..8626
                     /locus_tag="ACG804_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4833334.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(8907..10274)
                     /gene="nhaC"
                     /locus_tag="ACG804_002449"
     CDS             complement(8907..10274)
                     /gene="nhaC"
                     /locus_tag="ACG804_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HFS4833335.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
BASE COUNT         3198 a         2242 c         1909 g         2969 t
ORIGIN      
        1 ctctccaaac ggtataatcg tttggagagt tttattttaa tcagtttttt tatgttatat
       61 gttatatttt ttattcgttc acatctaatt cgatttccac cccgtagtga tcactgatga
      121 ttggactatc gatcccatca aaaatccgtt gatatttttt aacctgcatt ccttcaggga
      181 cgaaaataaa atctatacgc aatttttctg tattttgttc ccaaccatct attttctttt
      241 ccacagtagc tgcttttcct ttttcattcg cgacaacata cgaatcttga agaagaaggc
      301 aactttctct tacagtataa taaccttgag agtctactgg attattgaaa tcacctagga
      361 aaaaaagtgg tacgcgagtt tccaaaaagt agttttccaa gtttttccac tcaaaataaa
      421 agccactttt tttatctgtc caccaagaaa agtggcagct cgagacaaaa atgtcctgat
      481 catctatctt tgttttccca atcaagatct tgcgtgtctg ataatcttct ttcttttgaa
      541 attgggagac ggtaaggacc tgactttcca atgttttttt cgtaagcagt gcatttcctt
      601 cttcatattt atcataaccg atgtggctca tttcccaact ccaaaaatac tcttttccgt
      661 gttcctttaa aagctgaact aaacggtagg caaaattatc tttacggata ggtacttgat
      721 tctttaccgg acagaacttc attagcttcg caggttctac ttcttcagat tccagtaatt
      781 ggttgatttc ttgtaaagca atcacttcat aatcttctaa caggatctta tctgctaatt
      841 cttgcaattt tttctctggt tctggctcaa gccagctatg cgtgttgagt gtcatgaatt
      901 tcattggttt tctccttgtc ttcatttcga aacaaaaggg ttgtgacaaa atttttgtca
      961 caacctctcc agcaaatagt gttctcctgc taactcctca gtaataagct caatggacca
     1021 ggagctattt tttgtttggc tgtttttatc acttggtgca gggcagcttt ttcacgacct
     1081 ctccactaaa cagtattcaa actgctgctt ctcggtaata agcccaacca aacgaaaaat
     1141 aggaggagct atttttgttt ggctgttctt atgacttgat gcaggacagc tttttcacaa
     1201 cctctcctta cattttaatg gagccgatca ctttaccagc tgtcactgta cctaattgct
     1261 tgatcactac ttcttctact ttatcgtttg taaatacgat catgatcgtt ggatcttttt
     1321 cttcgttttg gatcacatca agatccatct cagctaattt cgttcctgtt cctacttctt
     1381 ggccttcttt gacagcaatc tcaaaagctg gctgattcat ttggactgta tcgattccca
     1441 tatggatcaa aacttcgata ccatctttcg tttccagccc aattgcatgt ttgctaggga
     1501 aaatacttgt cacttttcca gcgatcggcg caacaacttc tcttgatgtt ggaataacag
     1561 caaagccgtc acccatcatt ttttgtgaga ataccggatc ttttacttca gataaaggaa
     1621 tcacttctcc agaagctgcg gaaactagtt cttgttctat acctaagtat tgcttactac
     1681 ctgcttgtcc atttcctgta gaaaccattt ctggctctgg aatctctgct cctgattgca
     1741 gcagatcttc gatatctgat ttcaagacat ctgcttttgg tccataaact gcttggactc
     1801 cattgtcttt gacgatcaat cccatcgccc ctgctcgttt ccaggcttct tcagtcccta
     1861 ctttttctcg atcatttaca cttacgcgta accgagtcat acaagcatcg acatctttga
     1921 tattttcttt tcctcccagc aaatgaatga tctggaccac ttgctgatct gctgttcctg
     1981 ttccgctgtt agatacaacg gtttcttcac tgtcattgtc gtaatttccg ttacgtcccg
     2041 gtgtagcaaa gttgaatttt ttgatcaaga aatttgctaa gaaatacgta acaacaccaa
     2101 aagcgatcac acacaacacg aagttgataa gatctccacc tagacccgct ttgatagcta
     2161 acggtgtccg agtcagcaat tcgatattcc caaatgaatg gacccgcaat ggcaagatat
     2221 ctgccatcgc aaatgcagcc ccttggatca ctgaataaat gacatataat ggcacagcag
     2281 caaacataaa catgaactcc aatggttctg ttacacctgt tagaaagaca gccaacgctg
     2341 ctgaaaaata cattgattta tatcttgctt tcttatcagg atcgacatta cgatacatcg
     2401 caaaagccat tcccatcaag atacctgaag aaccaatcat ttgtcctact ttgaaacgag
     2461 ccggcgtcca gttatgcaac acaaactcat attgcgacat atcccctgca cctttaagat
     2521 tcactaaatc agtggcccaa gccaaccata acggatcttg cccaaatact tgtgtccccg
     2581 cctgtgcgcc tgataaaatc tcatacgatc cgccaagctg tgtatagttg ataggaatcg
     2641 tcagcatatg atgcaatcca aatggcaata gtaaacgttc taatgttcca aataaaaacg
     2701 gtgctagaat cggtgcgctt tcttgtgatt ctgcaatcca taaaccaaaa ttattgattc
     2761 cagcctgtac gtttggccac accacagcaa gaatcaatgc cacgattgtt gaccataaga
     2821 taacaacaaa cggaacaaag cgctttccat tgaaaaatga caaagcatcc ggcaattttc
     2881 tataattata gtacttatta taagccattg ccccgacaaa tccagcgatg atccctacga
     2941 atactcccat attcaaagct ggtgcttcca atacacttgt aaaaaatcct ttaaccatga
     3001 tcttcgtacc gaacagagtg tgggtaaatg catcttcatt cgcaagcatg tcacttgtga
     3061 caccaaagat agccccagtg atccgattga ttaaaataaa tgagatccca gctgcaaatg
     3121 ctccgcctgc tctttctttt gcccaacttc ctcctattgc taaagcaaat aaaatatgaa
     3181 gattaccaat aattgcccaa ccaatatttt caattactcc gcccgttgtg acaagcggcg
     3241 tccaatcagg attgatcaag ggaattgatt tccctatact gatcatcaac ccagctgccg
     3301 gcataactgc taccacaacc attaaagcct ttccaaattt ttgccaaaac tcaaaactaa
     3361 atatcttttt cattccgttt agctccttta cgcaatcggt ttcgttaaac gtattatagc
     3421 gtgcgttttc ttttttgtaa atgctttatt ttttattttt ctgtctatac cattctataa
     3481 aacctataat acgtgtgttc ccttctataa ttttctccta aaaatttatt tttttaagct
     3541 tttttctatg aaatattttc ttttgtctat tgacttgtgc aatcggttgc gtttattatg
     3601 aacgtataaa acagctcatt aggaggagaa aaatgaaaca gatcaaacga ctatttgcta
     3661 ttgatccatg gaaaatcagc acgacacaat tagataaaaa aaatcttcga ctgcaagaat
     3721 ctttaacaag tattggaaac ggttatatgg ggatgcgcgg gaactttgaa gaaacttact
     3781 caggggacca ccatcaaggt acttatttgg cgggtgtctg gtatcccgat aagacacgtg
     3841 tcggctggtg gaaaaatggt tatccagaat actttggaaa agtgatcaac gccttgaact
     3901 ttatcgcgat agatatttcg atcaacgatc agctgatcga cttggcttct ttggaaccag
     3961 aagactttta ctgggaatta gatatgaaaa atggtgtatt atctcgtaca ttcacaatca
     4021 ctacttctac taataaagta cgcatttcct tcgaacgttt tctgagcatt gtcaaaaaag
     4081 aatcagctta tatctattta actatagaaa tgcttgaagg tagcggaaca gtcaaactcg
     4141 tatcaaaatt ggatggaaat gttcaaaacg aagacagcaa ctatgatgaa catttttgga
     4201 atgagattga tcgtggaact atagaagaaa tcggctattt gacgactaaa actattccaa
     4261 acaactttgg gattgaacaa tttactgtta ctgcagcaat gcgccatttc gttaatggaa
     4321 aatcagtcat ccctgactat cacgaagata ctttagcatt acatggttgc ttgtctgcag
     4381 aattatctca aggtgagaca tggtcagtgg aaaaagaaat tatcgttctt actagtagag
     4441 atattccaga agcgcagcaa gcagaaaaag ctgtctcaga attaacgaac cagacaaaca
     4501 attatatcca agcaaaagaa gagcaaacag cggcttgggc agaacgatgg aagcttgccg
     4561 atgtggtcat cgaaggagac gaagaagcac aacaaggtat tcgattcaat ttgttccaac
     4621 tattctctac ttactacggc gaagatgaac gattgaatat cggccccaaa ggattcacag
     4681 gagaaaaata cggcggagcc acttactggg atacagaagc gtatgctgtc cctctttatc
     4741 ttgctttagc caaacctgaa gtaactaaga atctgctgaa atatcggcat aatcaactgc
     4801 cgcaagcaat ccacaacgct cagcaacaag gattaaaagg cgcgctttat cctatggtca
     4861 ccttcactgg tgtcgaatgc cataacgagt gggaaatcac attcgaggag attcaccgaa
     4921 atggcgcgat tgcctatgca atctacaatt atacgaatta caccggcgat acggaatatt
     4981 tgaaaaatga aggactggaa gttttagcag aaatcgcacg cttctgggca gaccgtgtcc
     5041 atttttcaaa acgagcaaat aaatacatga tccacggtgt gaccggccca aacgaatatg
     5101 agaacaatat caataacaat tggtatacaa atacgatcgc agcttgggtc ttgcgttaca
     5161 cgcgagaaaa ttatttaact tatcaaaaag aagctgctat cactatcagc gaagaagaac
     5221 tagccaaatg gaaagatatc gcagagaaca tgtacttccc agttgacgaa gaattaggaa
     5281 tctttgtcca gcatgacaca ttcttagata aagatctcat gcctgtatcc gatattccca
     5341 caagcgatct tcctctgaat cagcattggt cttgggacaa aatccttaga tcttgcttca
     5401 tcaagcaggc agatgtacta caggggattt atttcttcaa tgatactttt acaaaagaag
     5461 aaaagcaaaa aaactttgat ttctatgaac caatgactgt ccatgagtct tccctttcgc
     5521 caagtatcca ttcgatttta gcagcagaat taggaatgga aagcaaagct gtagaaatgt
     5581 accagcgaac agctcgcttg gatttggata attacaataa cgacacagaa gacggcttgc
     5641 acatcacttc catgactggt agctggttgt cgattgtcca aggatttgct caaatgaaaa
     5701 ctgcccatga tcagttgaga ttcgcaccat ttctgccaaa aacttggaaa gcttattctt
     5761 tccatatcaa ttatcgcgga cgtttattgt tcatctcagt cacagatgaa caagttactt
     5821 tcgagttatt agaaggttct cctctagaaa tttacgtcta tgaacagtct tattctttag
     5881 cggatcgtct agaaataacg ctaagaaagg aggaagcaaa tgtttaaagg ggtattgttt
     5941 gatttagacg gtgtcattac cgatactgct gaattccatt atcgtgcttg gcgaaagctt
     6001 ggtcaggaaa tcggcattac gatcgaccac acattcaacg aacagctaaa aggcgtcagc
     6061 cgagaagact cactctcttt gcttttagct tatggcggaa aagaacactc tttttcaaag
     6121 gaagaatttg cagaattagc gaaaagaaaa aacgattatt atttagagat gatccagacg
     6181 atcgaaccaa aagatgtctt ccccggggtc gtgcctttac tggattcttt aaaagaagaa
     6241 aaaatcaaga ttgctcttgc ttctgcaagt aaaaacgggc cattcctact tgaaaaaatg
     6301 ggtcttacac cttactttga tgctattgcc gacccggcag aagcaacaaa cggaaaacct
     6361 gcgccagata tcttcctcct tgcagcaaaa gctgtcggac taaaagcaga agaatgtatc
     6421 gggatcgaag acgcgcaagc cggtatccaa gccatcctct caagtggcgc tcaaccaatt
     6481 ggcgtgggac gtgctgaaga ccttggagag gagatcccgc ttgtccctga tacgactttt
     6541 cttacgatcg attacttgaa agaaaagtgg catgaccatg gataatccag agatctccgt
     6601 cgtaccagtt ccagagactg aaataaagaa aatcacattg aagaacgact acttagaagt
     6661 cgttcttctc aattacggtg cccgcctgca ccaaatcttc gcaccagaca aagaaggaaa
     6721 atcagaaaat gttttattgt cttacgatcg tttcgaagat gttctaacag acaaaagctt
     6781 ttttggagca actgtcggac ctgtagccgg aaggatccgg gatgcttctt ggggtgagca
     6841 tagattggag aaaaactgcg gatcacacca tatccacggt ggcacgaaag gctggtcttt
     6901 ccaattttgg gaagtagaag ttttcaaaac tccatcatca ataggtgtgg tcttttactt
     6961 aaaagatgaa ttttctacct atccaggacc aatcactgct acgatcactt accgtttaac
     7021 aaaaaacgaa ttagagatga caacctctgc tagtagcctt gttgaaacca tctgcaatcc
     7081 gaccaaccat gcctacttca acctttcagg aaatggaaca agagacatct atgaacatca
     7141 gttaacggtc tttttagatg gtgtgcttga attagatcaa gaaaaactgc ctactggaaa
     7201 ttggacaaaa aaagaaaaac tgccaatcga ctttagaaaa tccccaacac tgcaagagat
     7261 ccttgcatgt tatccagatg gactagatga tgtatttctt ttgcatcatc ctaggctttc
     7321 caaaacttcc ttacaattat tcgagaagca ttctggtcgc caaatgacta tagcaacttc
     7381 taataaaagt atggtattat tttctacgac tggattcgaa gctgatttct ctgtcaatgg
     7441 aaaacagatg cattcaaact acggattagc aatcgaaccg caagaaatcc ctgatatcgt
     7501 tcatttcccc aaatttggat cgatcaacct ccatcctggt caagaacgga tcagtcagac
     7561 gatttatcgg ttctctgcac aataacaaga gaaaggtgtt tttatcatgg ctattaccgt
     7621 aaaagatgtg gcgaaaaaag ccggtgttgc cacctcgacc gtctctcgtg tcatcaacga
     7681 tcatcctagt atttccgaga caacaaagaa gaaagtccga aaaattatgg atgaactagg
     7741 ttatgttcct aacatgactg cccgcaatct aggaaaacgc atttccagtg ccatcggcgt
     7801 aatcttaccc cctcttgatt caaaagagcg gatcggtaac ccattttatc ttgagatcat
     7861 ggaagcaatc aacgaagaag cgcggaatta tgatatgact acagcaatcg ctactgctaa
     7921 aaattttgaa ttgctgttag agaacgtcca gcgtatgcat ttacaaaaac aagtagatgg
     7981 ttttattcta gtgtattcag atagtcaaga tactgtcatt gattatttat accaaaacca
     8041 catccctttc actttgatcg gacagcctta tcatcatgag aacgaaatcg tttatgtaga
     8101 taatgataac cagcttctag gtaaacaagc aacagaattt ttgatccaga atggacataa
     8161 gaatatcctg tttgtgacaa acacgactca tgaaagtttg tatttcgaac gatatttcgg
     8221 ttatcaaaaa gcaatgatga tggctggtct tcctgcgtta tccagtgtag tactagagca
     8281 tccggaggat tatctgtcct ttgagaaaac gttgaaagaa aacgaagcca cagcattggt
     8341 ggtcattgac gatatcttcg cccttcgcac gatgcagttg gcgcaaatgt atggctatgt
     8401 cattccagag acactctccg tcattagctt caacaactcg atcttctcaa cattaacaca
     8461 cccttacctt acaagtatcg atatcgatat ctccgaatta ggacgtgtcg ctatgcaaaa
     8521 gctgcgcgaa ttgatccatg aagaattgag cagtggcgta cgtttggtca tccctcatcg
     8581 cttgatcaaa agagagacag tcgttccttt agaaaaccca tactaaatag ctgactcact
     8641 aaatacgctg accatttatc ctatggtcag ctttttatgt aaaagaagat actacttcta
     8701 acacattgtt tatctgtaaa aaagagcgtg ggacaaaagt aaagaacact tttgtctcac
     8761 gctctaaaca cgtataaacg gcggaagcag aagcaactcc ttcggaaata agctgaaatt
     8821 cacaaaaatt taaaaagcaa ttttcttgag tttcttctta tttcttggag ttaaacgctt
     8881 ctgtcccagc ctcttttttc cttccttcaa ttttttacac gtcgacgatt caataaaaaa
     8941 ccgcctaata ttgtaaagac aggtgcaaga atcgagaaaa aggcgaatgg caagtaatgc
     9001 aacgcgctaa ctttcatcgt tcccataatg aatgtgccgc tgactcccca cggtacgaga
     9061 gaattgacgg tcgcacctga atccgctagt gttcgtgtca aataggtttt tgataagcca
     9121 acgtcatcaa aagaacgctt gaatgtttct cctggaagaa tgatggacag atactgttct
     9181 ccaacgatca gattgattcc gatacagctc aaggcagtaa acccgactaa acgagaaggt
     9241 cggtccatct tttcttttaa ttcttgaacg atggtatcaa cgatcagata tttgatcagt
     9301 aacccaccta atgccaatgc aagtaaaatc aaactagcag aacctaacat actcatgatc
     9361 ccgcctcgag aaagcagttc atctagcttt ggatcaggtg tatttgcgac ataaccattc
     9421 atcaagatgt ctgctgcttt tccgaccgtc aaacttttct catggataaa agaaagaacg
     9481 agagcagctg tcgatcccgc tagtaatgta gggatagccg gaattttttt gattgccccc
     9541 ccaaataaaa taactagtgg aatcaatgtc caaggagaga tccaaaagct cgctttcatg
     9601 ttttggatca tttcattgat actagctaga tcggctgaat gactgttatg tcctaatatc
     9661 gtataaaaaa tcaacgaaag gacgaatgct gggaaatccg tataacgcat accagcgata
     9721 tgttcgaata gattaactcc tccaataccc gctgccaagt tggtcgtatc tgataaaggc
     9781 gagcagttat tccctaaaaa ggcaccggaa acgactgcgc ctgtagtcat tgcatcattg
     9841 aatccaagta aatgaccgat ccccaaaaaa gcaattccaa tcgtcgaaat cgttgtaaat
     9901 gaactgccga cagtcactcc gacaattgca caaacaagaa atgctgtcgg taaaaagaaa
     9961 cgcacagaaa caagtttaaa tccataaacc ataatcgtag ggatggttcc agataaaatc
    10021 catgaagcaa ctaagacacc aatcaaaaga aaaatcagga ttggaatgat ccctggagtg
    10081 attcctttga tgatcccgtc atggatctca tcccatgtga actttttaaa tctgccataa
    10141 aacaacaaac acatgaaagc tgcaaggatc gggatatgtg gcgagagctg gaatccgatg
    10201 atcagtactc ctaggagtgc caacaacacg atcaatacag cgatactttc ttttaaagaa
    10261 atatttttat tcatcgtcga tctcctattt caaatgaaaa ggccctgcca tgaaaaaa
//
LOCUS       DAZUJR010000095         9870 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.096, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000095 DAZUJR010000000
VERSION     DAZUJR010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9870
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.096"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(18..263)
                     /locus_tag="ACG804_002450"
     CDS             complement(18..263)
                     /locus_tag="ACG804_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HFS4833336.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(378..956)
                     /locus_tag="ACG804_002451"
     CDS             complement(378..956)
                     /locus_tag="ACG804_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFS4833337.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(1033..1563)
                     /locus_tag="ACG804_002452"
     CDS             complement(1033..1563)
                     /locus_tag="ACG804_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HFS4833338.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(1567..2427)
                     /gene="rlmB"
                     /locus_tag="ACG804_002453"
     CDS             complement(1567..2427)
                     /gene="rlmB"
                     /locus_tag="ACG804_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HFS4833339.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(2420..2815)
                     /locus_tag="ACG804_002454"
     CDS             complement(2420..2815)
                     /locus_tag="ACG804_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HFS4833340.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(2812..4224)
                     /gene="cysS"
                     /locus_tag="ACG804_002455"
     CDS             complement(2812..4224)
                     /gene="cysS"
                     /locus_tag="ACG804_002455"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HFS4833341.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(4221..4757)
                     /gene="epsC"
                     /locus_tag="ACG804_002456"
     CDS             complement(4221..4757)
                     /gene="epsC"
                     /locus_tag="ACG804_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase EpsC"
                     /protein_id="HFS4833342.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(4843..5082)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(5079..6539)
                     /gene="gltX"
                     /locus_tag="ACG804_002457"
     CDS             complement(5079..6539)
                     /gene="gltX"
                     /locus_tag="ACG804_002457"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HFS4833343.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(6709..7866)
                     /locus_tag="ACG804_002458"
     CDS             complement(6709..7866)
                     /locus_tag="ACG804_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HFS4833344.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(7900..9270)
                     /gene="radA"
                     /locus_tag="ACG804_002459"
     CDS             complement(7900..9270)
                     /gene="radA"
                     /locus_tag="ACG804_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HFS4833345.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(9333..9860)
                     /locus_tag="ACG804_002460"
     CDS             complement(9333..9860)
                     /locus_tag="ACG804_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HFS4833346.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
BASE COUNT         2507 a         2213 c         1784 g         3366 t
ORIGIN      
        1 tcaggctcgt ttgcttttta aactgcttca gttaaaaatt cgatctcaac tgtccgagta
       61 agtacatctg aatagctgta agatactcgt tcaaaagaat tttcttcagg atccaaatca
      121 acaacgaata ctgaaggata ggtttctgtt aaaacgccgc ggcgttctgt ttgacgcttt
      181 cttcctgtct gagcaaccaa catgattggg ctgccgatac gaccttctaa atctttcttg
      241 attgaagcta aagttgttgg catacagttc acctctacta tcaactatac cacatatttt
      301 taaaattttc aagtttacca taaaaaaaaa agaaatgcaa taaaaataaa taagaagctc
      361 attaagattt ttctaaatta ttcctcatta taaaatttca agtgtttttt tattttgagt
      421 tttactctcc cgtaagcgct cattacttgc ttgtgatcca ttgctaaaca ttcagccatg
      481 tctacaaaat caacgccttg catataataa tgaaaaattt tagcttctat ttttgaaaac
      541 tggatttcgc aattttcgat tgcttctttt aataaaagat gctgaatcgc taaaggttct
      601 tgcaatgtga tctctgctaa aaagtctggt ccttctgtct ctattttttg gtcgattgag
      661 acttcatctt tttgatcacg acgcttcagc gcgttctgct tcctcaacag agaatagatt
      721 tgattgctta taatgctttt ataataactt ccaaagctaa cacctttgct tttttcgtaa
      781 gttctcaatg cctgatataa agcgatcctt gcttcttgtt cccaatcctc agaaacataa
      841 tttcttaaat aataggtgtt tttcaaacgt agtaaaagtg gaaaatattt ttgatacagg
      901 gcagcaaatg cttcttcgtc accattacgt gcagcgcgca ataactcctc agacataaaa
      961 taattcctcc ataaattcgt ttatggagga atcttatcat caatgattca tcgaactgat
     1021 tagaacgata tgttatttat tttttctcat taaatcgtcc aatttttggg acaatttttt
     1081 taactgctct tcattccatg gagaattacg tcggaaatca ataaaatgca tatctttatt
     1141 ttcttgggct attgtttttt ccgttttttt tatcgtctta tataattcat aagcagaagt
     1201 tcgtaatgct ccttgggaaa agatcatcca ctgttctgct aaatcgcttg tcgccactgt
     1261 cacttgtgtc aaacggtcat tcagctgacc agcgattctc tcgatataac tgtcagccgt
     1321 ttcgtcttct ttcgtaaaaa caacatccaa ctggtatttc ttataatttt gttggatgcc
     1381 cggaactagt tgggcatcga agacaacgat gacttccatt ccttcatatt tcgcataatt
     1441 tgataaacga tgtaaaagag cttctcttgc atccgccatt ttgtcctgct ttttaagctg
     1501 gacaagttcc ggccacgaac caatcatgtt gtagccgtct acaatcaaca gctgtttttt
     1561 catggtctac tccccctgac gttgggaaaa agcctgatac ataagcaaac cagcagcaac
     1621 actggcattt aagctctgga cgtgcccggt catcgggatc gtcagcaatt catccatttc
     1681 ttttttcaat cctggactca ttcctttgcc ttcattacca atgactaaag caattgatcc
     1741 tttggcattc catttttgga agtttgtgcc ggtcatatct gtgccaaata cccaaaatcc
     1801 tgtttctttg agctgttgca cagcttgtac caaattcgtc acgcgtgcaa cagggacatg
     1861 ttcgactgcc ccagtggaag tctttgttac gataggtgtg attccaactg ctcggtgttt
     1921 tggtatgatc acaccatcga cgccacttgc gtctgctgtc cgtaaaatcg acccaaaatt
     1981 gtgtggatct tcgatgctat ccaaaatcaa aaagaagggg tcttcttttt tctcttttgt
     2041 tcgttcaatc agttggtcaa gggataaata ttcataaggt gtaatcgcaa gaacgactcc
     2101 ttgatgcacg ccgtgatcgc tcaaagtttc taatttttgt ttaggaaccc atttgactgg
     2161 cacagcttgt tcacgtgcga tttctttcag ttcttctact ttttctcctc gtgaatcttc
     2221 ttgaagaaag agtttattcc ctcgcccttg ttgtagcgct tctactgcgg catggtgccc
     2281 aaagacgaaa ttatcttcta atgcttcttc attttgatca gaaactgact gatttcgtcc
     2341 agtttgcttt ttatttgaat atctattttg ttttttgtct tcaaatccac gtttcgattg
     2401 atgtttgttt gttctttctt tacccatttt tttcaccaac tttctgaata caccagcgga
     2461 tcaattcttc catccgctcg gtttgttttg tcaaatgcag atagcccatg agcgcttcga
     2521 accctgttgc gacccgatac gtcgtaacat cagcattttt tgcgctcgta tggcttttag
     2581 catttcttcc tctgcgataa taaagttctt cttcttctgt caaaagatgt tcttccagca
     2641 tttgctgaat caaaaaggct tgtgcattcg cagaaacata attcgttgcc gcacgatgca
     2701 gcttattggg ttttgtttct ccttgatcaa tcaggtggtc acgaacatag atttcgtaaa
     2761 tcgcatctcc aacataagcc aaggctaaac cgttcaattg tgtgtaatct ctcatgcttc
     2821 tcttctccat cgggttcctt gcggtgtatc ttctaataag atcccttttt ctttcaacaa
     2881 atcacgaatt tcgtcgcttc ggacaaaatc acgattgctt cttgcttgat ttcgttcttc
     2941 gatcaattgt tcaatctctt catctaataa ctcttctgct gtaaataaaa taccgaagat
     3001 cgaaagccat tgcgagaata aagcttctcc ttgtgccaag acagcggcag aaactttcgg
     3061 ctggtctaga taagtgttca gccacttagc aagctcatag accactgtga tcccatttgc
     3121 tgcattaaaa tcatcgtcca tttcttcgat gaatcgctgt tctaaatttt ctaacaaagc
     3181 gattttatcc gcatcatctg ccaaattctc tgaggcagtt tcttggcgga atttcaaatt
     3241 gtcaaacgta ttcttcagtc gttgtaaatt ggtggctgct tctttcatcg tcgtttcact
     3301 gtagcggatc ggacgacggt attgtgtggt cgccatgaag aaacgcaaga cttgtggatc
     3361 aacgtttttg atcatttcat gtacagtgat gaaattccct agagatttac tcattttttc
     3421 atcgtcttcg ccaatcgtta catagccatt gtgcatccag taattagcga attttttccc
     3481 tgttttcgct tcactttgtg cgatttcatt ttcatgatga ggaaattcta aatcttgccc
     3541 gccaccatgg atatcgatcg tttctcctaa atgttttgtt gccataacgg aacattcaat
     3601 atgccaaccg ggacgtcctt tgccccatgg tgaatcccaa gaaatctcgc caggttttgc
     3661 ttgtttccat aaagcgaaat ctaatgggtc ttctttttgc tgctgttctt cccctgtacg
     3721 ctgacttgct ccgacttcca gttcatcgat ggattggtca cttaatttcc cataattttc
     3781 aaatttacgg gtacggtaat acacatcacc tgaagattca taagcatagc ctttttcaac
     3841 caacacttga ataaatgcta aaatatctgg catatgatcc atgactcttg gatgcagtgt
     3901 agcaggctcg acattcaacg ctttcgtatc ttcttcaaat gctcggatga aacgatcagc
     3961 aacttctggt gctgtaatac ctaattcgtt tgctgtacgg atgattttat cgtctacatc
     4021 cgtgaaattc gatacgaaat cgactttata gcctcgatat tcaaaatagc gtcgaattgt
     4081 atcgaaagca atggtgctac gagcatttcc gatatggata taattataca cagtcggtcc
     4141 gcagacatac ataccgacat gtcccttttg tatagggatg aattcttctt tttttctggt
     4201 caatgtattg tagattttta tcattctgat ctcctcactt tttctccttt gattcgaacg
     4261 acttttgctg gtactcctac cgctgtagcg tcgtctggaa catctttcaa cacaacggca
     4321 cctgcaccga ttttggcgtt ttttccgatc gttaccggtc ctaatatctg cgcattcgca
     4381 gagagcatgg ctccttgttt aacagttggg tgtcttttac ccgtttcttt tcctgtgccg
     4441 cctaatgtta cgccatggaa taaaatcaca tcgtcctcga tttctgcggt ttcgccaatg
     4501 acgattccca ttccatggtc gatgaacacg ccagttccaa tcgttgctcc tggatggatc
     4561 tcaacaccag ttaggaaacg ccagaattga gcattgatct tcgccaataa aaagagccgg
     4621 tgctgatata aaaaatgaga gaaacgatgc caaaacaagg catgaaaacc agggtatgtc
     4681 aaaacgatct cagctgtcga acgtgcagcc ggatcgtttc tctttgctgc atcaatcgct
     4741 cgggtaaacc aactcatgac tttccactcc tttcgtaaga attttatgta ggaaatcatc
     4801 ttcttataaa gaaaagaagc gccttttaaa taagtttcct tatcaaaaga cgctttccgc
     4861 gtggttccac ttttcttcat aatcaatgat tatctctgac agctaacgcc tgttatacgt
     4921 tcttggctac tttgtttcct ataaaacagt ttttcctgtt ttctgtgttt cgccaagacc
     4981 actcccagag gcatttcggc aaccattcat tgataccttg caccacccgg tatctctctt
     5041 gtaatgatca gctgcttact tttttctgtt catcgtgttt agttcagtac ttgatttaaa
     5101 tgtgctaatg atttttcacg accaagcaat tcgatcgttt caggcaattc tggaccatgc
     5161 atttgtcctg atacagctac acggattggc atgaaaagat tttttccttt tacgccagtt
     5221 tctttttgaa cagctttgat ggcagctttg acagttggag catctactac ttccatttgt
     5281 tctagctgtg ctttgaatgc gtggagaaca gtaggaactg tttcaccagc aagtacttct
     5341 tttgctgctt cattcaatac aggatgttca ttgaaaaata gcgtagacag atcaacgatt
     5401 tctgcagcat agctcatttg aggttgatac aggctaacga tcttcttcac ccattcgatt
     5461 gtcttttcat ctgggttttc tgctacacgt ccatcagcga ttagataagg cagacacatg
     5521 tcagtaaatg catctagatc cattgctttg atgtaatggt tgtttaccca ttgcagtttt
     5581 ttcgcatcga aagctgcggg tgatttactt aggcgttttg gatcgaacat tttgatcaat
     5641 tcttggtgtt cgaagatttc gtcttcgccc acaggtgacc agcccaataa tgcaataaag
     5701 ttgaacattg catctggtag atagcctaat tcgcgatatt gttcgataaa ttgcaagatt
     5761 gattcgtcac gtttgcttag ttttttacct gtttcactgt tgatgatcaa tgtcatatgt
     5821 ccgaaggttg gtggtgtcca gccaaatgct tcatagatca tcagttgttt tggtgtattg
     5881 gcaatatggt catctccacg taaaacgtga gtgattttca tcaaatgatc atcgaccgca
     5941 acagcaaaat tataagttgg cataccatcg cgtttttgta tgacaaagtc gccaccgata
     6001 ttatcggatt cgaacgaaat agcgcctttc accatatctg taaatgcgta ttctgtattg
     6061 cgaggcacac ggaaacgtac aacagattct agaccttgtg cttctttttc tgcttgttct
     6121 tcaggtgtca agttcgcaca tgttcctgcg taatgaggca tttctcctct tgcgcgttgt
     6181 gcttcccgtt ctgcttctaa ttcttcttct gtgcaatagc atttgtatgc tcgattgcta
     6241 gcaagcagct gatcaatcag cggttgatag atttctttac gttcagattg acggtaaggg
     6301 ccgtattctc caggattttc aggagattca tcccaattca ttcccaacca agcaaggttt
     6361 tccaactggc ttttttcgcc atcttcgata ttacgttttt ggtcagtatc ctcaatacga
     6421 ataataaagt ctccatcatt gtggcgggca aacaaataat tgaataatgc agttcttgca
     6481 tttccaatat gcaggtgccc agttggactt ggtgcatagc gtacgcgtac tttcgtcatt
     6541 ttcttcctct tctttcaaac tagactttga ctaacagcaa aaattccgtc agttacggct
     6601 tctcaaatat catttattta aagccactca gcacaaattt taccttttct aaggtaaata
     6661 gtaaagccaa ctggttgaat ttccttacca gttggctgaa tttctttttt attttgattg
     6721 tttagtcttt ttctctgtct cttttttatt gtcgattcct cgtcctgcat gtgcaggttt
     6781 agcaaagatc atgcgtccag cagctgtttg aagggcactt gttacaacga cttcgatacg
     6841 ttcattcatg taatgctgtc catcttctac gacaaccatc gtgccgtcat caaggtaggc
     6901 tactccttgt tggcgttctg tcccggcttt tactactaga acattcatcg tttcaccagg
     6961 gatgacgact ggttttacgg catttgccaa cgcattgata ttaagaacag gtacattttg
     7021 gaattcagag actttattca agttatagtc attggttaca atgacaccat ctaaaagctt
     7081 agccaatttg atcaatttgc tgtctacttc actgatatct tcaaagtctc catcgtacat
     7141 ttcgacagat ataccctctt ctttttgcaa ggcatttagg atatctaatc cgcgacgacc
     7201 acgcacacgt ttcaaactat cccctgagtc cgcgatgtat tgtagttcgt aaagaacaaa
     7261 attagggatc atcaaggttc cttctaagaa tccagtcttt gtaatatcat aaatccgacc
     7321 gtcaatgatc acgcttgtat ccaagatttt atatttatgg aaattttctc ctgattttcg
     7381 ttctaacagt tgactctcaa cttgactagc tgtttcttgc tcgatttttt tgcttcgtga
     7441 accaaaaact ttcttccatt cttcgattcg tgtcgttccc attctcaatc ccagatagcc
     7501 taagatgatc atcagtaaaa tcggcaatac actattgacg aatggaattt ccatattgta
     7561 aagaggggtc gagatcacaa cacctaaagt caatccgatg atcgcaccga tcgcaccgaa
     7621 gagaagataa gtcaagctga cctcacttag tttttgttct acttgtttga taatagctga
     7681 gatatgtttg gccaacagca aagataataa aaagaaaata agtgcgccta acaggctgtt
     7741 ggtaaatgta ttattcagcc atccgtttga ctgttgaccg attgcctgcc aagctgaggg
     7801 taaaaatgaa atacccaagc ttgcgccgac aatgatcatc agcaaagtaa tgacacgttt
     7861 ttgcatcgtt tttcctccgt ttcgacaatc atttattagt tagcggaaca cacgcttcaa
     7921 cgtttcagcc aaagttgcta ctccaactat ctcgattcct tttggcgctt cccagttacc
     7981 taagttgttt ttaggtaggt atacttttgt gaagccgagt ttttggactt ctttgactcg
     8041 ttgttcaata tgactgacac gtctgatttc tccagtcagt ccaatttcac cgatgaaaca
     8101 ttccgttggc tgtgttcctt tttctttata gcttgaagca atactgacag cgatagctaa
     8161 atcaatcgct ggttcattta attttacccc acctgcagct tttaagtaag catcttgatt
     8221 ctgaagaagc aacccagctc ttttttccag cactgccatg atcagagata cccgattgaa
     8281 atcaagacct gttgttgttc gtttggcatt tccgaacata gtaggtgtga ctaatgcttg
     8341 gatctctacc aaaattggac gtgtcccttc cattgccaca acgatagcag agccagttgc
     8401 accgtctagg cgttcttcta agaaaatctg tgaaggatta gcgacttctt ccaatccatg
     8461 ctcatgcatt tcaaaaatcc caatctcatt cgttgagcca aatcggtttt ttactgctcg
     8521 caaaatccga aaactatgat gttgttcacc ttcaaaatat aacaccgtat ccaccatatg
     8581 ttctaacatt cttgggccgg cgatcgagcc ttctttggta acatgaccga cgataaaaat
     8641 ggctatccca tttgttttag cgattttgag tagttctgca gtggtttctc ttacttggct
     8701 gacacttcct gccacacttg tgatgtctgg ctgcgtcatc gtttggatgg aatcaatgat
     8761 aacataatca ggggagatat gttcgatggc acgactgatt tcgttcatat ctgtttcagc
     8821 gtatagataa aattctgtgt tgatacttcc gaggcgttcc gcgcgtaatt ttatctgctc
     8881 tgcgctttct tcgccggata catataagac ttttccgcct atggctgcta attgctgaga
     8941 aacttgtaac agcaaagtgg atttcccgat acctggatcg ccaccaatca agaccataga
     9001 ccctggcacc acacctccgc ctaacacacg gttcagttct tctaattttg ttttgatccg
     9061 aggttctttt ttagggacga cgtctgcgat ttttgttggt tttgcttttt ctcctgtcaa
     9121 acttgtccga gttctgcggt ccgttgtatc ttgttcgatt tcttcgacca tcgtattcca
     9181 ttttccgcaa tttgggcagc gtcccaagaa cttaggcgac acatacccgc aattttggca
     9241 aacaaattgt acttttgatt tttttgccat tgtaccgcct ccttttatcc taatcatgag
     9301 acattaaatc aagcttaagt atctttaacg ttttatttac tggaagaacc aaatccgcct
     9361 tgacgttgag cagtcgtttg atcttgatct gcttttaaaa acggcaaaaa gatcccttgg
     9421 ccgatacgct cgcctttttt gatcactaca tccttgaaac caaagttggt gaattggaac
     9481 atgatatggc cttcatttgc ctcattattg taataatcac tgtcaatcac acctactccg
     9541 tttgtcaaca ctaaaaaccg cttcaacgga ttgcttgaac ggttagcaag ctgcaaaaat
     9601 tcatcttctc ccatgtaagc tttgattcca gtaggcacga gggttggttt caattgtttt
     9661 tcattttctg atacatcttt tttcaatcca tctgcgactg tttccaaccc ctttttccag
     9721 cctgctttcc agatacttgg aatcacgacc tcttctgctg cttcaaaatc atagccagca
     9781 gcatgatgtg tagcgcgctg cggtagattg atattttgat ctttatattt agaaataact
     9841 tcaaatcctc tttttctcac cggttttcct
//
LOCUS       DAZUJR010000096         9532 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.098, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000096 DAZUJR010000000
VERSION     DAZUJR010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9532)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9532)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9532
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.098"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     regulatory      complement(22..88)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01734"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Fluoride riboswitches increase expression of
                     downstream genes that help mitigate the toxic effects of
                     very high levels of fluoride; They are found in a wide
                     variety of bacteria and archaea; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="fluoride"
                     /db_xref="RFAM:RF01734"
     gene            complement(130..777)
                     /locus_tag="ACG804_002461"
     CDS             complement(130..777)
                     /locus_tag="ACG804_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HFS4833347.1"
                     /translation="MEQTIKPYQYFFIKREVDQLLNAYSSVNDPKTVQTVQALAAEKI
                     RDILEHELPEIDTFLTTVLDVKLTKAQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQEHTYIGWNDPGTQKKFMVYYEDEKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
     gene            complement(1056..1559)
                     /locus_tag="ACG804_002462"
     CDS             complement(1056..1559)
                     /locus_tag="ACG804_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFS4833348.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(1682..2446)
                     /locus_tag="ACG804_002463"
     CDS             complement(1682..2446)
                     /locus_tag="ACG804_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HFS4833349.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     NAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLADVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            2553..2828
                     /locus_tag="ACG804_002464"
     CDS             2553..2828
                     /locus_tag="ACG804_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HFS4833350.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            3505..4455
                     /gene="yidC"
                     /locus_tag="ACG804_002465"
     CDS             3505..4455
                     /gene="yidC"
                     /locus_tag="ACG804_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0051205 - protein insertion into membrane
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HFS4833351.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPANNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(4634..5608)
                     /gene="lacD"
                     /locus_tag="ACG804_002466"
     CDS             complement(4634..5608)
                     /gene="lacD"
                     /locus_tag="ACG804_002466"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HFS4833352.1"
                     /translation="MKKMSIEKQERLKRLTDEAGIISALAIDQRGALKKMINQYKEAT
                     SEDIIQFKQMVSQYLTPYASAILLDPEYGLPAAALREKECGLLLAYEKTGYDTKIPGR
                     LPDLLNIWSVKRLKEAGADACKFLLYYDVDEPAEINVQKQIVIERIGSECEAEGIPFF
                     LEILSYDATIGDPSSLAYAKVKPHKVIEAMREFSKERYQVDVLKVEVPVNMRFVEGYG
                     QETCYSQAEASAYFYEQSKVTEQPFIFLSAGVNATLFQDTLRFAKQSGSTFNGVLCGR
                     ATWAKGVAPFVTEGEEKASSWMLEEGKQNIKELSTLLEETATPVYVDR"
     gene            complement(5605..6063)
                     /locus_tag="ACG804_002467"
     CDS             complement(5605..6063)
                     /locus_tag="ACG804_002467"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose PTS transporter subunit IIA"
                     /protein_id="HFS4833353.1"
                     /translation="MTIIHEENIFLQQPLDSQEEAFKFLAKQTFCLGIALDEKEVYQK
                     LLEREKEGTTGIMSGFAIPHAKSQTINEPSMIIATLNKGIEWNSLDRQSVDFIFALFI
                     PDSEAGTTHLKLLSLVARSLMRKEVTEQLRKAKSKTEIATILTKEIGEDL"
     gene            complement(6060..7523)
                     /locus_tag="ACG804_002468"
     CDS             complement(6060..7523)
                     /locus_tag="ACG804_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HFS4833354.1"
                     /translation="MGKYQLIAATGCPTGIAHTYMAQEALEQAARKKGIKIKVETHGQ
                     IGIENELTAEEIKQADAVIIAADKDVHSERFAGKRVIDVSVSTGIKDAQRLIDEALAG
                     KGTVLADNEAADTLEPEAMSGANFGRSIYKNLMNGVSHMLPFVVAGGVLIAISFAVWG
                     IYSFDPDHAQYNATAAMVKAVGDAAMGMMVPVLAAYIAEGIAKRPGLVVGFVGGIVAM
                     NGGTGFLGGILAGFLAGYFILFLQKLLTILPKQLDGLKAIFLYPVIGVAFIGIVMSLL
                     AGPMKAINEGMMSFLAGFEHSNPLVLGVIVGCMCAFDMGGPVNKAAYVTGTALLAQGN
                     TTFMAGVSAACIAPPLITGFATLLFGKYFDTNDRNAGLVNFILGSTHITEGAIPFAAK
                     DPIRVLPTMMLGSSIAAVLTYLFGVQVPAPHGGFLVLPVVTGKIQWVTAILIGSIVGG
                     VILGLIQKKRVTDKDKKMDNKAANRTVIEKGRAGDLS"
     gene            complement(7505..8455)
                     /gene="pfkB"
                     /locus_tag="ACG804_002469"
     CDS             complement(7505..8455)
                     /gene="pfkB"
                     /locus_tag="ACG804_002469"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HFS4833355.1"
                     /translation="MSIYTCTMNLAIDLFIETEEMHPFMVNRTKEDDIQANGKGVNVS
                     LVLKMLDFPSTALGFSAGFTGKYIEDYLQQKQIQTEFIEVPGMTRINVFTQVNQTGEE
                     YKLVNQGPKIPQTAVHNFLNQIRALQAEDYLCVSGSLPRGLSPKVLIEISRICQEKGI
                     HLIIDSSDQEAMDCLPYRPFLLKPNEEELSSWFGRKMVTDEDYFVYGQRLVELGAENV
                     LLSLGEKGAILFTKDRVFRGNSPKGKVVNTACAGDTMLGAFLAGYMNRRPLDETLRKS
                     IAAGSSTAFRKGLTDFLDVEELSKQIKIKEERFETWENIN"
     gene            8598..9347
                     /locus_tag="ACG804_002470"
     CDS             8598..9347
                     /locus_tag="ACG804_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFS4833356.1"
                     /translation="MDHKLSETEQYLWNFIEHHILEIPNYSIVKLSEQANVSTATIVR
                     TMKKKGYEGFTSFKHHLKEGENKNINFSFLDKVDKGIRRAILKNEQEVVRTINMLEIG
                     NIEDAIQRIKFADRVFVFARGFSEMIGQEMLVKLQLTGKNCQMHTDPEIIKSISRKLT
                     KKDSVIFVSLNGETKELVTAAKNCYDAEIGSILVTANHSSTLKDYCEINLVGFKSEGS
                     YFPDYEVRSRLPLQIIARILLDAYVLRMGEN"
BASE COUNT         2855 a         2007 c         1643 g         3027 t
ORIGIN      
        1 aaagaaaggg gctatcccca gactttagta ggcgtcatta gctatctttc gttagcattt
       61 aaaggcgaac accatcacct attcacttcc attaaaagat agcatatttt tctgtaaaaa
      121 acaataaaat tatcgttctt tctttacacg ttcagcaaat tcatagaaag gagccaattt
      181 cgttaactgt tgattacatt ggtcactatc atgacaaata taattcccct ttttcgtata
      241 cgtgccatca gaacctgctt tcgttgtaga aagaaaaagc gacacattcg atgttttctg
      301 acagattgca cagattccct tatttatcgt tggtgataaa gtaccgctaa tcccttttaa
      361 tttttcatct tcgtaataga ccatgaattt tttctgcgta cctggatcat tccagccgat
      421 gtacgtatgt tcttgcaagt cgatttcatt ccaagctggt tgtttgagtt ttttcacttt
      481 tcggaataat ttctcgattt gtggtttgct aggctgcata aacggctgga cgatttgctt
      541 cagctcctcc aatgctcttt ctgcttgcgc ttttgtcagt tttacgtcta aaactgtcgt
      601 taaaaatgta tcgatttctg gcagttcgtg ttctaatatg tctcgaatct tttcagctgc
      661 tagtgcctga actgtttgta ccgtttttgg atcattgaca gatgagtacg catttaataa
      721 ctgatctact tctcttttta taaaaaaata ttggtatggt tttattgttt gttccatgat
      781 tttaaagtcc tttcttctaa ccaaagtgca tactttgtag aaaaaagtga tcttctgcaa
      841 agtatgtgtt acctgaagat cccggactct tttaaataag atacgttttg catcttatca
      901 tcaccccctt taatgttcat tcttctatgt acatgattca ttcgataaat aaaagtaaac
      961 cgtatcttga acagatagtc aactgcaaac agaaaaaacc gagaaaatca gccagatttt
     1021 ctcggaatat agtctattat tattggtttt acctattaaa tcgaggattc tttcccaaag
     1081 taacgttgcc atctcttacg catacttgca gacatgggct gagccgcttc tttgactgcg
     1141 cagtatttgt ccacgaatgt cacaatatat ccttctttat acttaggcgg tgcgatcgtt
     1201 gcaccccaca tgtgcttcaa aatgatatct cgctcaagat ccgacaaatc ggtgattttt
     1261 tctgcattct ttacagcaat tcttggatgg atatacgcat gtgtcccctc gtcaaatttc
     1321 gtcgtacgcc aatcatagta gaacagatca tgcaaaagtc cagcacgcgc tgttgcttta
     1381 gcattgccac cccatttttt tgcgagcaga taactatagt aagaaacact gatggaatgc
     1441 tccaaacgag tggaatgaac atgctgtgtg taattcgcta attttttcac tgcttctgtt
     1501 tctaaaagat cttgtacata agacatatat tcttcgtctt cacgccattt ttctgtcata
     1561 attatcgatc tgccaccttt ttgaatttca ttttcttctg aaattgatct aagtatacca
     1621 ccagtgttcg gattattcta gtcgctctag ataaaatagc taaagcttaa tagttcctta
     1681 atcataaaga aaaatgataa agaacgatcc ctgctgcgac tccgacattc aatgattccg
     1741 catttccttt cattgggata tatacgttct gatcagtcaa agacaagatt tcctgactta
     1801 ctccctgacc ttcgtttccc atgattatag cgaaatcctc tgttttttct actttgtcta
     1861 atgcatgtgc ttcttcattt aattctgtac cgtacaccgt aaaccctttg cctttcatta
     1921 cagggattac atctgccaaa tctttttgta acacaggcaa atgataattg cttccctgca
     1981 tgcttcgcag cacctttgta ctataaatat ctgccgttcc tttacctaat aaaacaccag
     2041 ccataccaaa cgcatctgcc gtacggatca tcgttcccac atttccagga tcctgtacat
     2101 tatctagtaa aagccagcct cctgaaaaat ctggcgtatc ttcagatgtt aacgtcatca
     2161 ctgctaagat cccttgcggt gtaggtagat ctgacatagc ggtcatgacc tcatctgaaa
     2221 ctagaaaagt agaaatctct ttgtttacag ccagccagtc tccccattct ttcatacctc
     2281 tctgtgtcac aaaaagttct tttatttctg cattagacga cgcagcttct tcgatcagat
     2341 ggaacccttc caaaagatat tctgcctttt cttctctgta tttcttttta tgtagttttt
     2401 ttaattcttt gattcttgga ttttttgctg attggatctc tttcacattc ctcacctcaa
     2461 ctgattatat catggaatag gtgcttgagc ttgtttcatc ctaaaaaaat cggtatcatt
     2521 gatttataaa acaggaaaga aaggtgacga acatgcgcaa agttaaaatg aatgtccaag
     2581 gacgtgtcca gggcgtggga tttcgctata tgaccaagat ggttgctgat cagttaggcg
     2641 tgaccggaac ggtaaaaaac gaagacgacg gctcagtcac aatcgaagca atcggaaatg
     2701 acgacatcat ccaaaaattt atcgaagaag tcaagaagtc tccgagccca agtggacgag
     2761 tgcagtatgt ggatgtccaa gaagatccga tgattgagga acgaaagaaa tttgatgtag
     2821 tgggataagg ttgtgaaaag gtcgcttagt tttgagtatt aaggaaaatt ttgtgaaaat
     2881 ggctttccac atttttgcat aaatttgact taataccgag aaactgactt ttgaacaccg
     2941 tcgataaggt tgtttttgaa gcgctttgcc tcgagtatta aggagaaaca ttttcaaaat
     3001 agcttctcat attttgaaat gtaatgactt aataccgaga ggcagctgat aaaacaccgt
     3061 caataaggtt gtgaaaaagc tggtctgcat caagcattaa ggactggttg tgataaatag
     3121 ctctccatat ttttcaacag gctggactta atgccgtaga tgcaagcttt tgaacaccgt
     3181 cgataaggtt gtttttgagg cgctttgcct caagtattaa agacaggtag taaaaaagct
     3241 gatctataac ttgcaatgaa tttgcttaac ccatattttc cagacagaac aaaaaagttt
     3301 ttagtttttt aaataagaaa gaaacacttg gaatcactct tttctttcta agtatttctt
     3361 tcttgatttt ttgtcttttt tcaaaatttt tcgctacgaa aaagaacgaa tatttatatg
     3421 aaatttctat gaagttgatt gaattccatg cgctttttta gtatagttaa gtttgtgtaa
     3481 aaattataga agaggaagta ttctatgaat aaatggaaaa actggttatt gggatccgga
     3541 cttgtcagta tcctgctctt tttatctggc tgtgtgcgga tggattcaaa cggaaaccct
     3601 gacacttcag gaatcgttta tcgagtactc gtccatccta tgggccaagc gattacatat
     3661 ctagttgaga atttcaattg gtcttacggc tgggcagtta ttgcaatgac tgtgatcgtt
     3721 cgtatcatca tcttgccact aggtatcagt caatcgaaaa aaacaatgat ccaatctgaa
     3781 aaaatgcaag cgttaaaacc acaagttgaa gcagcacagc aaaagctaaa agctgcaaca
     3841 acacgtgaag aacaaatggc agcacaagca gaaatgcagc aagtatatcg cgaaaatgga
     3901 ttgagtatga ccggcggaat cggctgtctg cctctattga tccaaatgcc gatcttctct
     3961 gccttgtatt ttacggcacg ctacacagaa ggtatccggg aatcatcttt ttacggcatc
     4021 gatctaggct caccaagtat ggtgcttgtg gccatcgcag gggtcgctta tctgcttcaa
     4081 ggatatattt caacaatcgg tattcctgaa gaacagaaaa agacgatgcg tacgatgctg
     4141 atcgtctctc ctgctatgat cgtcttcatg tcaatcagtg cgccagccgg tgttacactt
     4201 tactgggtag tcggtggtgt gttcagctgt ctgcaaacat tcatcacaaa cgttatgatg
     4261 aaaccacgtt tgaaagcaca agtggcagaa gagttgaaac aaaacccgcc aaaacaagtc
     4321 gtcactccaa gaaaagacgt gacagaatca gcaaagccag ctaacaacaa acaagcaaca
     4381 aaacaaatca aacaaccaaa aaacagtaca aacaacaaag gccgcaacgc aggaaagcag
     4441 cagaagcgga agtagatagt aaataagagt gtaataaaaa ttcattaaca gttttagcaa
     4501 ttaaaaatat cgaccaagat ttttgaaaaa gaaatctggt cgatattttt atttaagtga
     4561 atgtttaatt tgaatcatcg attgatcgct atctaattgc agcagcatct ttttatgaag
     4621 aaacaacttt ttcttatcta tcaacgtaga caggtgttgc tgtttcttct aatagtgtac
     4681 ttaattcttt aatattttgt tttccttctt ctaacatcca actactcgct ttttcttcgc
     4741 cttcggtaac aaaaggtgcc actcccttcg cccatgttgc tcgcccacat aagacaccat
     4801 tgaatgtcga acctgattgt tttgcaaaac gtaatgtatc ttgaaatagc gtagcattga
     4861 ctcccgcact taaaaaaata aacggttgtt cagtcacttt cgattgttca tagaaatacg
     4921 cggatgcctc tgcttgacta taacaagtct cttgcccata tccttccaca aatctcatat
     4981 tcactggcac ttctactttc aatacatcca cttgataacg ttcttttgaa aattctcgca
     5041 tggcttcaat aactttatgt ggttttactt ttgcataggc aagagaagac ggatcgccaa
     5101 tagttgcatc ataagaaaga atctctaaaa agaaaggtat gccttctgct tcgcattctg
     5161 aaccaatccg ttctataact atttgttttt gcacattaat ctctgctggt tcatcaacgt
     5221 catagtacaa taaaaattta caagcatccg caccagcttc ttttaacctt ttcaccgacc
     5281 aaatattcaa taaatcaggt aatcttcccg gtattttcgt atcatagccg gttttttcat
     5341 aagctagcag taagccacat tctttctctc gaagcgctgc tgcaggcagg ccgtattctg
     5401 gatcaagtaa aatagctgag gcatagggag tcaggtattg agaaaccatc tgtttaaatt
     5461 ggatgatgtc ttctgatgta gcttctttat attggttgat cattttcttc aaagcaccac
     5521 gctggtcgat tgctaatgcg ctaataattc cagcttcatc cgtcaatcgc ttcaaacgtt
     5581 cctgtttttc tatactcatc ttcttcatag atcttcacct atttctttag ttaatattgt
     5641 ggctatttct gtttttgatt ttgcttttct caactgttct gtaacctctt ttcgcatcaa
     5701 tgatcgtgca acgagagaca ataatttcaa atgagtcgtt cctgcttctg aatctggaat
     5761 aaataacgca aaaataaaat caactgactg tctatctaaa ctgttccatt caattccttt
     5821 gttcagtgtg gcgataatca tactaggttc gttgattgtt tgagacttcg catgagggat
     5881 agcaaaacct gacattattc ctgtagtccc ttctttttct ctttctagaa gtttttgata
     5941 tacttctttt tcgtcaagag cgatccctaa acagaatgtt tgctttgcta aaaacttaaa
     6001 tgcttcttct tgactatcca atggctgttg taaaaaaatg ttctcttcat gaatgattgt
     6061 catgataagt ctcctgctct tcctttttcg ataactgtac gatttgctgc tttattatcc
     6121 atcttcttgt ctttatcagt tactcttttc ttttggatta atcctagtat cactccacca
     6181 acgatcgaac caataagaat cgctgtaacc cattggattt ttcccgtcac tacaggtaac
     6241 actaaaaaac caccatgtgg tgctggaact tggacgccaa acaaataagt taagacagca
     6301 gcaattgatg agcctaacat catcgtgggt aacactcgga tcgggtcttt cgcagcaaac
     6361 ggaatagctc cttccgtaat atgagttgat cctaaaataa aattaaccaa acctgcatta
     6421 cgatcattgg tatcaaaata tttaccaaac aataaagtag caaaaccagt aatcaacggt
     6481 ggtgcaatac aagctgctga cacaccagcc ataaaagtcg tgtttccttg tgccaaaaga
     6541 gctgttcctg ttacatatgc cgccttatta accggtcctc ccatatcaaa cgcacacata
     6601 cagccaacaa tcacgccaag aacaagtgga ttcgaatgtt caaatccagc taaaaagctc
     6661 atcattcctt catttatagc cttcattgga cctgccagca aagacatcac gatgccaata
     6721 aatgctacac caataactgg atataagaag attgccttca agccatctag ttgtttaggt
     6781 aaaattgtca gtagcttttg caaaaataag ataaaataac ctgctaagaa cccagctaaa
     6841 atacctccta aaaatccagt accgccattc atggctacga ttccaccaac aaatccaacg
     6901 actaaccctg gacgtttcgc gatcccttct gcaatataag ctgctaaaac tggaaccatc
     6961 attcccattg ctgcatcgcc aactgctttt accattgccg ctgtagcatt gtattgtgca
     7021 tgatctggat caaaagaata gattccccaa acggcaaatg aaatagcaat caatactccg
     7081 ccagctacca cgaaaggcaa catatgagag acaccgttca ttaaattttt atagatgcta
     7141 cgaccaaaat tagcaccact catcgcttct ggttctaaag tatcagcagc ttcattatct
     7201 gctaagacag taccttttcc tgccaatgct tcgtcaatca gccgttgtgc atccttgatt
     7261 cctgtactga cagaaacatc aatgactcgt tttcccgcaa atctttctga atggacatct
     7321 ttatctgcgg caataatgac agcatctgcc tgtttgattt cttcagccgt taattcattt
     7381 tcgatcccaa tttgtccatg ggtctccact ttgatcttga tgcctttttt cctagctgct
     7441 tgttctaatg cctcttgcgc catgtaagta tgcgcaattc ctgtcggaca accggttgct
     7501 gcaattagtt gatattttcc catgtttcaa acctctcttc cttgattttg atttgtttac
     7561 ttaattcctc cacatccaaa aaatcagtca gtcctttacg aaaagcggtt gagctgcctg
     7621 ctgctatgct tttacgtaac gtttcatcaa gcggtcgtcg attcatatat cctgctaaaa
     7681 aagcgcctaa catggtatca cctgcacatg ctgtattgac aacttttcct tttggcgagt
     7741 ttcctcgaaa caccctgtct ttcgtaaaaa gaatcgctcc tttctcaccg agggataaca
     7801 aaacattttc tgcacctaac tctactagtc gttgtccata aacaaagtaa tcttcatctg
     7861 taaccatttt tcgtccgaac caagaagaaa gttcttcctc gttcggtttc agcaaaaacg
     7921 gtcgataggg taaacaatcc atggcttctt gatcactact atcaataatc aaatgaatcc
     7981 ccttttcctg acaaatccga ctgatttcta ttaaaacctt tggagacagc cctcttggta
     8041 aactcccaga aacacaaaga taatcttctg cttgtaatgc tcttatttga tttaaaaaat
     8101 tatggacagc tgtctgcggt attttaggtc cttgattcac taatttgtat tcttctcccg
     8161 tttgattgac ttgtgtaaat acattgatac gcgtcatacc aggcacttca ataaactctg
     8221 tttggatttg tttctgctgt aaatagtctt ctatatactt tcctgtaaac ccagcagaaa
     8281 aacctaatgc cgtacttggg aaatctagca tttttaatac tagtgacaca ttcacccctt
     8341 ttccgtttgc ctgaatgtca tcctcttttg tgcggtttac cataaaagga tgcatctcct
     8401 ctgtttcaat aaatagatca attgccaaat tcatcgtgca tgtgtagata gacataacca
     8461 acgacctcct tgactctatt atgaaatacg cgaaagagaa aatgttttct taatcgtccc
     8521 aacacaaaga aaacctttac atttataaac tcgtcgtgct attttttaac taacttttgg
     8581 tgaaagaagg aaagaatatg gatcacaaat taagtgaaac agaacagtac ctctggaact
     8641 ttatcgaaca ccacatccta gagatcccta actactccat cgtgaaacta agtgaacaag
     8701 caaatgtctc aacagccacc attgtgcgga caatgaaaaa gaaaggctat gaaggattta
     8761 cttcgtttaa gcaccatcta aaagaaggag aaaacaagaa catcaatttt tctttcttag
     8821 ataaagtaga caaaggtatc cgtcgagcca ttctaaaaaa tgaacaagaa gtggtacgta
     8881 cgatcaatat gttggaaatc ggaaatattg aggatgcaat acaaagaatc aaatttgctg
     8941 accgggtttt tgtctttgca cgaggatttt cagaaatgat tggtcaagag atgctcgtaa
     9001 aacttcaatt aacagggaaa aattgtcaaa tgcatactga tccagaaatc atcaaaagca
     9061 tcagtcggaa actaactaag aaagacagcg ttatttttgt ttctttgaac ggcgagacaa
     9121 aagaactcgt caccgccgca aagaattgct atgatgcaga gattggttcg attctagtta
     9181 cagccaatca ttcctctaca ctgaaagact attgcgagat caatctcgta ggtttcaaat
     9241 cagaaggttc ttatttccct gattatgaag tacggtcacg tttgcctctc cagattatag
     9301 cgagaatcct gcttgacgcc tatgtattgc gtatggggga gaattgaaaa gcagtttatt
     9361 atggttggtt acagtttaaa acatcacatt ttttattctt tatattgtat ggactcacgg
     9421 aaacttttta tgtataaagt tattcacaat ctataaagtt actttaaata acaaaaaaat
     9481 aattgaaaat acttaaaatc aaaaaatatc tttttaatca ataaaaaaat tg
//
LOCUS       DAZUJR010000097         9497 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.099, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000097 DAZUJR010000000
VERSION     DAZUJR010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9497
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.099"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            170..364
                     /locus_tag="ACG804_002471"
     CDS             170..364
                     /locus_tag="ACG804_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833357.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            633..932
                     /locus_tag="ACG804_002472"
     CDS             633..932
                     /locus_tag="ACG804_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833358.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(1029..1463)
                     /locus_tag="ACG804_002473"
     CDS             complement(1029..1463)
                     /locus_tag="ACG804_002473"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4833359.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1695..2405)
                     /locus_tag="ACG804_002474"
     CDS             complement(1695..2405)
                     /locus_tag="ACG804_002474"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HFS4833360.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2395..3255)
                     /locus_tag="ACG804_002475"
     CDS             complement(2395..3255)
                     /locus_tag="ACG804_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HFS4833361.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3260..3898)
                     /locus_tag="ACG804_002476"
     CDS             complement(3260..3898)
                     /locus_tag="ACG804_002476"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HFS4833362.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3913..4212)
                     /locus_tag="ACG804_002477"
     CDS             complement(3913..4212)
                     /locus_tag="ACG804_002477"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFS4833363.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4255..5739)
                     /locus_tag="ACG804_002478"
     CDS             complement(4255..5739)
                     /locus_tag="ACG804_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFS4833364.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5759..6220)
                     /locus_tag="ACG804_002479"
     CDS             complement(5759..6220)
                     /locus_tag="ACG804_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFS4833365.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6238..7305)
                     /gene="ulaG"
                     /locus_tag="ACG804_002480"
     CDS             complement(6238..7305)
                     /gene="ulaG"
                     /locus_tag="ACG804_002480"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HFS4833366.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7523..8293
                     /locus_tag="ACG804_002481"
     CDS             7523..8293
                     /locus_tag="ACG804_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFS4833367.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8566..9393)
                     /locus_tag="ACG804_002482"
     CDS             complement(8566..9393)
                     /locus_tag="ACG804_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4833368.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
BASE COUNT         2962 a         1938 c         1485 g         3112 t
ORIGIN      
        1 tttaagaaca atagcctttt attatatata ttattcaaat tagttatatc gagtgaaaaa
       61 aactttcaaa ttgattcttt ttatttatca taaagatata gatacataat cattttcact
      121 tacatatatt tgaatattaa ctaaaaacag caagaaagaa gaggatcaaa tgtattatgt
      181 agaagtaaaa acaaaaggcg tcaaaaacaa acaatatgtg aaaggtatca gtaacgaata
      241 tcctttactt ggttcatgga aagaagctgc tcctttttcc aaaccatgtg ccataaaaat
      301 aaagaacgag ctagaaaaag aactgacttg tggtaaagct gttgtagata tcatcgaaaa
      361 gtaaatccaa tgtatagaaa ggaagatcac acatgaaaag cgacgtacaa attgctaaga
      421 ttatagaatt agaagaagaa gacgcagtgt tgacaattga aaaaaaataa atgtttgtat
      481 accatatgat tatttcaata tgtatcctgg aattggagat ctcgtagagc tatatcaaga
      541 tgaatcaaat atacttgtca ttcatcatga aatatagaga cttataaaat tgtttatttt
      601 tataatgtat cagtatagaa aggaaataaa acatggatta tactgttgaa tttgacagtg
      661 aactacttaa gcaatttcca caagaagaac atttcatgta taaagaagca atttcccaca
      721 aagtgacaga gtatttggag cataattttt ttcgtataaa gccagtgcgt actcgttcgg
      781 caaaaggaat atacgagatg aaagtcaaaa ttaataaaaa aaattatcgc atagcatttg
      841 ctttaaaaaa aaatcatgtg ttcatttttt atattagttc gaatttgcaa aaaattgtat
      901 ttgataaaga ggtgagtaaa aaaataaaat agctgagcat tggaggatag attgagtgat
      961 actaagtcta tcctcttgtt tttctaaaga actaagctag aattttttct tttgtacgtt
     1021 attatatgtt atttgtcatt accaaaaagc accttttttc ttctagtatc tatgacataa
     1081 gaaataccac ccatttcctt tacttgaaca aatcctactg attcataaaa tttttttgtt
     1141 ttctcagtat catctgtcaa taattcgatt tggactggtc cataactagt gatcttctcc
     1201 aaagcttcat tcaaaagcac tttgcctatt ccttggcgct gatacctcgg atgaatgagg
     1261 atatcttgaa taaatgcgat cgtcgcaaaa tcagtgatcc aacgaacgat tccgataatc
     1321 ttcccttccc cattacgctt tatcagagat tcagattgtt caaatgctct agctaacctt
     1381 gcagtgtctt ttgtgtaatt cgtccaacca acgctcttat ataattcaga aatctcatcg
     1441 atcataaggg aatcaatatt catttttttc ttcctttctt atacaattct ccctctaata
     1501 atacagttct ttgactattt aatctatcac atataactct cctgtaaaga ttctctcgat
     1561 tccttaaaat tcctctttcc ttttagaatg catacttttt gataaataaa aaggttgtga
     1621 taaattttct tcacaacctc tgtttctctc tatcaagtgt tatcttttaa ttttctaccc
     1681 ttaccctagc atctctattg cccgtagtat gcatactttc catgtttgcg aaaataatgt
     1741 ttatctagta aatattgcgg gatttcacat atattggggt tgatcagctc gttttctttg
     1801 gccatcagac aaatttcatc taagatcaaa ctgttttcta ctgctttcat aggtgaatcc
     1861 ccccatgtga acggtccatg tccatagaca agtactccag ggacttcgtt tggatctaat
     1921 tttctttcct taaacgtctc gacaatcaca ttccctgtat gaacttcgta agcttctctt
     1981 acttcttctt tcgttaattg gcgtgtacaa ggaaccttac cataaaaagc atcagcatga
     2041 gtcgtgccat aagctggcaa atcgcgtcct gcttgcgccc acatgacgga gtgcgtggaa
     2101 tgagtatgag taatagcagt tatatcttca aaagtttgat acaaaacaac atgtgtgggg
     2161 agatctgaag atggttttaa gctatcttct tctattatat ttcccgacaa atctgttacc
     2221 accatttgat ctgcttgcat gcattcatat ctgacaccgc ttggcttaat gacgatgact
     2281 cctagctcac ggtccacttc actcacattg ccccaagtca atttgactaa tccgtatcgc
     2341 ggcaatgcca gatttgcttc aaggacacgt tgcttcattg ctgcaatttt ttcttcacaa
     2401 gacatcatag ccagcctcct tcaatttaga acttaagtag tcttttgcct gctggatttc
     2461 tcttcgaaag tcttggcttt tttcactcca catttcaatc agaaatgttc catcataatc
     2521 tagacgtttc aaatgtctta ataatccaag aaaatcaaca caaccgctac caaaaggaac
     2581 atcacgaaac tggcctgaat attcttttgt tacagggtaa gtatctttta agtggatagc
     2641 agtgatataa tcgatccctt tctcaagttc tcgagccgga ttattttccg gccatgcgga
     2701 caaattgcct aggtctggat atacttgtag aaaaggtgaa tgaatctgtt ctttgatttc
     2761 taaaaatttt gaaatggagt tcataaatgg atcatccatg atttccacgg aaagaatgat
     2821 gccatattta gaagcttcct ttacgctttc ttttattcct tcgataaagt cttctctgga
     2881 attcattgat ttctcttcat aataaacatc gtatccagct atttggatta ctttgacgct
     2941 tagattatgc gccaaatgga ttgctttttt cattagttgt ttcgctgctt ttttcttttc
     3001 tggatcagca gaaccaaacg gaaatcgccg atgcgcactt aaacaaatcg aatggatacg
     3061 tacaccggag ctgaacatct cttctctcag ctcagctatc ttttcttcag accaatctaa
     3121 tcgtgctaac cgctcatccg tctcatcaat cgacatctcg ataaaatcga agtccatttc
     3181 ttttacaagg gaaaaacgtt ctttccatga aatatctttg ggtaacgctt tttcataaat
     3241 cccaatttga gccatttcct tacccccaga tacgaatgat ctcatctttg aagttttgtg
     3301 cggccttcat cggatcattt gctgctgtaa taccacgacc agtgataaag gtatacacat
     3361 cgatcccttc aaataagtgt aatgtgtgtg gatttaatcc accagttaca gaaacattaa
     3421 agcctagttc aatcagtttt ttgatcttcg ataaatcttt ttcaccccaa gtttcaccag
     3481 ataacagcgc atcacggctt tgatggtaga ttacctgccg gataccgatg ttatgccaat
     3541 ccatggcttg ttcaaaagtc caattgccgt agagttctac ttgcaattca cctatttctt
     3601 tttgtgctgc ctccatagtt ggaatcgttg cacaacaaat gactgtcatc cagtctgctc
     3661 ctgcttttgc aacattactc gccactgttc ctccagcgtc tgcacatttc gtatcagcga
     3721 ctagtttttt atctgggaac atactgcgaa tacagcgaat cgctttttgt ccttcctgta
     3781 agcaaagaat tgtgcccact tcaataatat ctactacatc accaactttc ataacatctc
     3841 ctaatgcatg ttctaagtca ttgtgatcta acgcaatttg caaattcggc ctgctcatct
     3901 tagttccttc ctttacttgt ttttttggta ccactttgtt tcagcaaatt tttcactgat
     3961 ttctttgact gacatcacat ttttgatacc gataactgta actccttttt tctctgcctg
     4021 agtaaacata ttcaaaaaat tgactggcgt aaaaactaca tcgtattggc cagctgaact
     4081 ttttccctct gaaatggcac aatgatggat tttggtaatt ggtacgttta gttctttcat
     4141 tgctttttcc acacttctca tcatcatcaa gcttgttcct gatccatttg cacacgatac
     4201 taaaattctc atcttaatcc ctccattatg agtgttgtct aatcagattt tcttttatac
     4261 tctctgcttt tctgcatatg tgtcatagtc ttctacaatc aaaaaataac catcaggatt
     4321 tttccgatat tgtaactgcg gaatagccaa taaaccaatg acaactacgg caattccagc
     4381 ataacctagg actttcatga ttactgtaaa caatggccaa gctgttgccc agtcgaacat
     4441 cccgatataa ccaccgtatg ttgacatccc aatccatgta gcgaataatg ctgaaccgcc
     4501 tacttgtatg attcctgaaa gaaacgggaa caggcaagcg gctttgaatc cacctcggtt
     4561 attggcataa actgctataa cggcattatc aaagaacaac ggaatgaaac cggctatgac
     4621 gatcgttggt gatttcaata aaatcagtaa accaatcatc aaaaactgtc ccaaagcacc
     4681 aaacaagaac ccaatcgtta ccgcatttgg cgaaccaaag ccaaaagtag cagctacgtc
     4741 aattcctgga acagctcctg gtaaaatcgt gtttgagatt ccttggaaag attgagttag
     4801 ttcatcgacg aatgtccgaa cacctaattg caagatcgcc agatataccg caaaatttaa
     4861 agaagtcgtc ataatgtaga ataagaaact ctgcccttct tgcatgaatt gcgcttgaat
     4921 caaataatct ttgcctagta caatcagaat gatcccaaag aaaaatagca tgagtaacga
     4981 agtagcaacc atattctcat tgaaaatcga caagaatcct ggtaatttga tatcttcaat
     5041 ttttttgtct tgcttgattg atctattttt cttttcatcc cgctttttca tccactcagc
     5101 taattttgca aatataaaga ttccgaacat ttgctgatgt gccactgcaa atccggcacc
     5161 ttctgtcaat tcctgcgtga ttcctactgt taagttagaa gctactgtcc aataacaacc
     5221 taaaatcagt cccataaaaa tcaatgcttg tatcctacct agatcaggaa agcaaaacag
     5281 taaaatccaa aaagcggtag ctgcttgttg aacctgaacg tttccggtag tgaaaacgga
     5341 acgcagtttc gtatatttct gaaaacggac taataagata tttaaaacaa atgcaatcag
     5401 taataaaatc atcacatctc caaaggtacg gccaaatgtc tccattaatc cagcatccac
     5461 agcattttgt ccaaaataag gatctgtaac catggcatcc aaattgaacc gttcctttag
     5521 tccaaccaag attggccgaa aattattgac caaaccacca gagccaacag tcaaaataaa
     5581 gtaaccgacc gttgccttta agaatccagc gatgcattca tgaagcgggc gtttcagcaa
     5641 aatatagcct aataacacga taaaaccaat caggtatgct ggctgcgtca agatatttgt
     5701 tgcaaaatac gtccaaatgc ttaacaaaaa ttcccccatc ttttttctcc tctatcaatt
     5761 aattatattc tgccatcaca acttggtaat catcgatgga gttcgtagag atgagacgct
     5821 caaccaatcc atctgtcatt aataattcgg ataatttttg gatattttct agatgttctt
     5881 ctggatcttt tgctgcgagt gtaaaaaaca aactagccgt tttctcctca ttctcccctt
     5941 cactttcaaa acggattggc tgtttcaact tggtaaatga aatagctgtt ccaaaaacac
     6001 catcactttt ttctgaagaa tgcggcattg ctacttgagg tgcgatcaca atataaggac
     6061 cgtatttttc tacacaatgg atgatctcct ccacatacgt ttcatcaata atttccttat
     6121 cgatcaatac aagacagctt tcggcgatag cttcacgcca atccgtgatt tctttatctg
     6181 ggtaatgaat caattgatgg tcaaaaaagt atttcagcaa gaaactcccc ttctttctta
     6241 taaaaacgac ggaaacggtg tatcattttc aatcgagaag acatcttcaa atcctcgata
     6301 aaaattaaac tcaagatcat ctttgtttgt cggatagatg aatttcccgc ctacttgcca
     6361 gatataaggt ttaaatccat acttcaggcg atcctttttg aatttccaaa tttcagtgat
     6421 ctcttttgga tcagccataa aattagacca aatatcgtag tggacaggaa tcactacttt
     6481 tgcattcaat gactccgcca tgcgcagcat atcaacagaa gtaactttgt ctgttatccc
     6541 tcgtgggttt tcaccatagg cccctaaaca gacatcgatt ttgtgttcat taccatgttt
     6601 ggcaaataaa ttggagtaat gtgaatctcc tgcatgataa agattccctc ctgatgtttc
     6661 gaataaatag tttactgcaa tttgatccat ctcctgaggc atttttcctt ttaatacctc
     6721 ttctggatct tcacaagtga ccaacgctgt ccgatcaaac gcttctaaag ctactacatt
     6781 gatgtctttg attttgactg catcacctgg ctttactgta atcgtttttt cttcaggaat
     6841 tccccatttt tgccacgtgc gaaccacttc ttttggccca atgaatgttg cttcaggaca
     6901 attttgatga actgctgcgg ctgtatggat atctagatga tcggaatgga tatgtgtaac
     6961 gattaaagcg tctacatttt ttatcgcaaa aggatcgatt acgaaaggct gagtacgtaa
     7021 attaggctgc atattttgaa cgccactcat acgcatcatc tgatggcctt ttttcatcat
     7081 gccattccca tgactacgtt ttcccgtccc acaccataga tcacataaaa tattcgttcc
     7141 ttcatgactt ttcagccaaa ttcccgtaca gcccagccac cacatagcaa aagttccagg
     7201 atccactact tctgtttcga tttcttcatt caagtatgtg ccccactcag gaaatgtttc
     7261 tactaaccac ttttcttttg ttacttcatt gacagtttta ctcatttgct tgctcccccc
     7321 atatcgttgt tccaacttac aagtaaatat taatgtgtat cagcatccat gaaaaccctt
     7381 ttatatgacc gtttgttttt tatatgattt tctttcagta atcaatgatt gtttcagtat
     7441 aataaagaca gatatgaatg tttaaatgaa caactagtca aataaatcca tggatcaaga
     7501 tgtccctcag gaggcaaaag tcatgaaaaa ctcacttgtc aatattgaaa aacgtcaaaa
     7561 agaaattttg gaactgcttc agcagactga acaactatca actttcgaat tagctgaatc
     7621 ccttgatgta tctattagta cgatacgaag agatttaaat ttattagaag aaaaaaacga
     7681 gatcatacgc aattacggtt attgttctta taattacaaa aaccagactg attttgatca
     7741 atctggtcct gaaaggatta aacaagcgat tgccagagaa gctagtaaat acattaacga
     7801 ttatgatacg ctgtttatca attctagctc gactgcgttg aaaacactgg attttcttca
     7861 atctaaccat ttgacagtca ttacaaacaa cgtgaaaatc aattactctc cgcacaaaga
     7921 taattgtagt tatattttaa ctggtggaga gatgcgcttt ccaaaagaag cactagtggg
     7981 cgacatcgca ttaaatacga tttcttcagt caatgcagac atttgtatca ttggctgtag
     8041 cggagtcgat gtagtacatg gggtcacaac aaagatatta aatgaatcaa cgatcaacga
     8101 aatgatggtc aacaagacaa tcaaatgtaa gattttagtc gctgatcatc gaaaaatcgg
     8161 actgacatca aagttcaaga ttgctgatat ttcagtcttt gattatttga tcactgataa
     8221 attttgttct gaaaaagtat tagaggagat cagaaatacg gggataaaaa ccattcaagt
     8281 agattcattt taagaaccag gacgtaaata tgtaaatagg attatcaaaa aaatgaataa
     8341 caaatttatc gataaatgaa aaacacgcta cgctcaaatt gataaaggaa tcccaagatg
     8401 tatccatcca atcgatacca tcataatcta ttgcttcttt tataaccgtt atatgttgcc
     8461 taaataggaa tcaaacaata tcgaaaaaag gaggtatgac aaaagtcaca cctccttttt
     8521 tcgaataaac ggtattcaaa tcagaacact gatttcacaa ccactttatt tcaggtcgtt
     8581 ttcaatcacc tttaccgcgt aatcatttcc gttgaaacgc gctatttttt ttgcgtccat
     8641 atatctttct aaataatcat cttctcctaa ttgcttatgg caagaagcaa tttcataaag
     8701 caagtattcc aatgcataag tcgatttatg tttcttatta tactcaatac ccttctcaca
     8761 taattggatt gctttatcat aatcctcgat tttacggtaa taggtggcga tatcataata
     8821 tacaatgcag accatcagat tatcaaaatc agtctcactc aatattttaa gtgtacgctc
     8881 cacataaact ttcgcaaaat ctaattctcc ttttgacaag tagatcattg ccacgtttgc
     8941 agctgcttgt aagtgatgga tatctgtttc ggtcgtttgt tccaacactt gattaaaata
     9001 aaataatgct gcatctggtt ttttcgcata aagatgatca agcagtcctt gataaaataa
     9061 aatttgattt aaaagatcag aattacttac tttttcctga tcgatcgttt gtaaaatttt
     9121 ataagattct tggtattttg atacagaatt caatgattga atctcattta tttttttcct
     9181 gattttgtct tcttctgttt ctactaatat atcggagatc tcgacattca gctttttgca
     9241 aagcgcactt aagatattga tgcctggcga catattcttg ttttcgatat tgctgacagt
     9301 tgcttgttca caaatgcctt ctgctaattg tacttgtgtt aacccctttt tctttcggta
     9361 ttcttttagt aatgctccat ctactttaat caaaacaatt tccttccctt taaaaaatta
     9421 tttctccttt atatcataca caaaaaaaag ttctaaacaa ccaaaaatgt ttagaacaga
     9481 ataaaaattt taatttt
//
LOCUS       DAZUJR010000098         9136 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.100, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000098 DAZUJR010000000
VERSION     DAZUJR010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9136
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.100"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(46..1020)
                     /locus_tag="ACG804_002483"
     CDS             complement(46..1020)
                     /locus_tag="ACG804_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HFS4833369.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(1001..2884)
                     /locus_tag="ACG804_002484"
     CDS             complement(1001..2884)
                     /locus_tag="ACG804_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HFS4833370.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(2902..5127)
                     /locus_tag="ACG804_002485"
     CDS             complement(2902..5127)
                     /locus_tag="ACG804_002485"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HFS4833371.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            5242..6276
                     /locus_tag="ACG804_002486"
     CDS             5242..6276
                     /locus_tag="ACG804_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4833372.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(6343..7356)
                     /locus_tag="ACG804_002487"
     CDS             complement(6343..7356)
                     /locus_tag="ACG804_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFS4833373.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(7434..7622)
                     /locus_tag="ACG804_002488"
     CDS             complement(7434..7622)
                     /locus_tag="ACG804_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HFS4833374.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            8169..9128
                     /locus_tag="ACG804_002489"
     CDS             8169..9128
                     /locus_tag="ACG804_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFS4833375.1"
                     /translation="MTYTHLTTDELVIIESYFKINQSVAKTAHCLNRSRQTIHKVYLF
                     FKKGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     VDEFFIQSVASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
BASE COUNT         2654 a         1887 c         1667 g         2928 t
ORIGIN      
        1 ctttgtcttg taaactccgt ttttcaaata ataatctaaa gattgctact gaataataaa
       61 gccgatttca tggtcctctt cgctgctgat tcggtaaggt gactcaacat ccgctcccca
      121 gctattgata cccccgactc ctcttacttt tgcaaaaatc gtaagaaccg ttcgtctttc
      181 tggcggtagt tcttctatat gtgttgcctg ttccagttct tctgctttga atggtaaagc
      241 ggaaaaagca aatggcgtat cctgctgttc aaatcgcaac gaaaaatctt cttgatcttt
      301 atccgtatta tccaacgttt gatttcttgt tagttctacc catttcgttt ccatatgcat
      361 gccgcattct tggggaacaa ggtatgggga aacggggagt cctgccactt tataaatacc
      421 ttcgacacca ccagccatcc gatccggata tgtttcccct gataggcctt catactcaaa
      481 aaattttgct ttcgttggca taatgaacct taaacccaat gcgggtaatt ccggtaatcc
      541 tttttgtcca taataatgca tattgacaag cattttaccc tctccagcga tttggtagga
      601 aattgtcact tgggtttttg gtactgtgtt gatttccagt gtaaaaatga tttcaaccgt
      661 ttcagcgtat tcattacttg aatattgatt atttactgga gcaatcggca aatcgatctt
      721 tttattgtcc accagtactt ctatttcttt gacttttgga tacaatccgg ctcctaacca
      781 cataccggat ttaaatccaa atccgctacc tctgtcatta tcggtcgttg ctcgccaaaa
      841 aactggaagt gtttcccggt atagccattc ttttccgttt ttattgagcg attccagtcc
      901 gcctcttgta taagaaaaaa tataatgcgt attccccgat ttgacaccta atgtacagtc
      961 gccgaagacg attgcaactt tttccgtatc catatgactt ttatttactg tatttttcat
     1021 aataatatct tacctcctgc atggcgggtt tttcttgtcc atctgcaaaa acgatcccat
     1081 tccctgagaa ttcatagtca cttggtttat cgtcaaagtc accgccatag cgcatcactt
     1141 ctctgcctgt gattggatca gtcacttgga tcgcctgatc tttaaaatcc catatatagc
     1201 ctccttggta catttcataa cgatcaagca acgtcatgta agaatccatt ccacctaacg
     1261 aattccccat gtcatgcata tattcacata agatgaacgg tttttccgct ttattttcaa
     1321 ggtagtcaat gatctcttct ggtggcgcat acatgcagct ttttacatct gaaatcgaat
     1381 cttcgaatgc tggatttgga aaattccctt cataatggac aagtcgatcg gggtctactt
     1441 ttttgaagta atcgttcatt tgtcgaatgt tttcttccgc ataagattca tttccaagag
     1501 accaaaaaag aatacttgga tggtttttta atgtttcgaa attcgttttt gctcgatcaa
     1561 gaacagccgc ctgccactga ggtactgcac ctggtacgtt gtaagaaggc tcaaatgcgc
     1621 ccattttttg ccatgagcca tgggattcga ggttcgtttc cgccatcaca tggattcctg
     1681 cttggtcgca taaataatac caagtgatct ggttggggta atgagatgtc cgtacgccgt
     1741 tgatctttgc attttttatg atagccaaat ctttttccat atcttctata gtgatggcgc
     1801 gtcctttttt cggatgccac tcatgtcgat ttaccccgtt gataatcatc cgttttccat
     1861 tgaagtagat gattttatct ttgatttcga ttttacgaaa accgaaggaa tagtcaatat
     1921 actccgttac tcttttttct tcgtctatcg tctccaattc aagcttatat aaattgggct
     1981 gaaaatgccc ccacagtgcc acattttcaa atccatcgat gcgaatcgtc atttgctctt
     2041 ttaacggata ttgctgttga tagatttcct tcccatcagg atctagtatc gctacattca
     2101 gctgactgtt tttggctact tgctcaaaag acaaatctac ttcaagtttg ccattttgac
     2161 atttgtcatc taagcgaggt ttgatccaaa gatcttctaa atggttttgt cctcgagcaa
     2221 ctaagaagac atctctgaag atcccaaaaa atcggaaaaa gtcctgatct tccaagaatg
     2281 cagctgtact tcttttgtaa acctccacag ctagaatatt ttcttcttcc aaataaggtg
     2341 ttaaatcaaa ttcagacgga gtgaacgaat cttcggcata cccgataaaa tgaccattca
     2401 accaaataaa cattgcttgt tctacaccag caaaatgaat cgagatttgt tttcccttta
     2461 gaccttcttc taatcgaaaa gtcgtcaaat acgaaccaac cggattgtct ttagcagctg
     2521 aaaagatccc ttccgcctct ttctcagggc ttgtcgtgaa agggggacgg cgaaatacat
     2581 gtccctccca cggatacatc gtattgatgt aatggatctt gtcataattt gctaattcaa
     2641 tatgactagg aacagtgatt tcatcaaaag aacaggcatc aaaatctttt ttataaaatg
     2701 tttttggtcg taccgaagga tttggcgaat aacaaaaacg ccatgatcca tttaaagact
     2761 gtttaaggga ggatgtggtt tctacttctt cccttgttgc ataacaaaca tgatcgctat
     2821 gtgcatttga ttggttcact ctaaaaactt gtggatcatc taaccatttt atatttgctt
     2881 tcatactttt ttccttctct ctcataactt tttgaaatga agcagttctg tttggaaatc
     2941 accttgaaaa tcggggaagt aaagtccaac tgtcatcaat tcggcccccg aaaatatccg
     3001 cttcgaggtc tgttcctgat aaagtgcctc atcatctaac cccatcagat atacttcatg
     3061 gaacgctggt tgagctgaag ctagtatcct ccctaaaaac acaatagctt catcttgttt
     3121 aggagacaca aacatccatg cggcaatatt ttcttcaaaa ggactcgcca aacgataata
     3181 atggccatac tggatcaccg gacgaatcgt ttgataggat ataatttggt cttttacttg
     3241 ctttttttct tcaggagaca gctttgtcaa atccagttca taaccaaaaa cagcgctcat
     3301 agctgtttct cctcttgttt tcaacgaagt agatctgtcg gtctgatgat ttggtacagc
     3361 tgatacatga gctgtgatgg acgaaatcgg ataagcaagg cttgttccat attggatttt
     3421 catacgctcc actgcatccg tgttatcact tgtccatgac tgcggcatat aataaataaa
     3481 cccggcatca aaccgtccac ctccaccaga acagccttcc cataagattt ccggataatc
     3541 agttgtcaaa tgttcaagta gttcataaag cccgagcata taacgatgcg ctacttctcc
     3601 ttgtctctgt gggtcaaggg taatcgaata gacatctgaa agcgaacggt tcatatccca
     3661 tttgatgtag tcaagaggaa tcgtatctaa aatctttctc atttgtttct caatcgtctg
     3721 ccgaacatct aaccttgtaa aatccagtac atgttgtgat ctggaagcag aaggcattct
     3781 acctggctcc tgcataagaa aatcaggatg tgttcgatac agttcagaat caaccgagat
     3841 catttcaggt tcaaaccata aaccaaattt caatcctttg ctatgagcat aatctgctat
     3901 ttcacgtaat ccatttgtca acttgccttc atactcgaac cagtctccta atgaagaatt
     3961 gtccgcatct ctttttccaa accagccatc atctaatacg aacatttcga tgcctagctc
     4021 ctttgcttca tcaatgatcg ccttgatttt ttcactattg aagtcaaagt aagtggcttc
     4081 ccagttattg accagaatcg gccgttcagc aaattgatga cgacctcttg cgattctttc
     4141 acgtagcaac tcatggtgga tctgactcat tttgttcaat ccctgacttg agtaagaaag
     4201 gatcatttca ggtgtttgaa aagactggcc tgcattcaat tcccacgaaa aacgatggct
     4261 gttgatccca ccgacgactc tcaattgatt gatctgatct ttttcaagtt cgaaagaatg
     4321 gttgccggaa taaacaaatt gaagtccgat cgcttctcca gtattttctg tcgtatgatg
     4381 atgaactaaa gcaataaagt tattcatatg gtgactgctc gttcctcgac ggctttcaaa
     4441 tacttttgtt ccagataaaa cagattgccg tgaaatctgt ctttcattga catgtgctcc
     4501 tggcaaagca atgacttcat caaatcgcct agtatgggca aagtctagct ggaaactagc
     4561 cgctttttct agtttgattg tttctccggt ttcatttctt atctttacag atcgtgtgat
     4621 cactgctcta tcagtaaata tggtatagaa caaatcgaaa taaatcgctg tttctctatc
     4681 cttaagtgaa atcaccaacg tttgtgcctc tgacttgtcc atcacataag tttgaggcaa
     4741 gccttcgatc tctggcttcc catctgtaat ataatggctg tcatatctca gatccagtaa
     4801 gtctgatcca ttcttgcgct gaatgatcga tgcgggcgtt cgaaagtcca tgctgccatg
     4861 agaagagtat tcttgcggta gtgtatcttt cgacagagac cggtcaggat ttaagggaac
     4921 atttcctgaa aatccacgat ctcttcgggg ataattttta ttgtctttgt actgcttgac
     4981 tggtttgcca aaataaatat gcgccaatac attgctttct tctatcttta tcagataaga
     5041 aagaaatgta tttcgtaaat ggaagactcg gctcttttca tcaaataaga tgaaattttt
     5101 atctgttttt ctatgcgtaa tatccatcat ttcactccca acaaaacgga aaccgtttac
     5161 ttttttttat aattcctgta tactgtttac taaacaattt tgtcaataaa aattttttat
     5221 ttttttgagg agtgtgtaaa aatggttgga attagagatg tcgcacgaaa ggcaaatgtc
     5281 tctcctgcta cagtttcccg tgtgttgaat aacgatcaga cgatccatgt ggctcagact
     5341 actcggcaac ggatagtaga ggcagctgct gcgttggatt atgacatcag tactcgtaaa
     5401 tatatcaaaa agagaatgcc ttcgattggt gtgatctcta cgatcggcaa agcgagcgaa
     5461 gaacaggata tctattacaa acatttgcga gtagggatgg aagaagaagc tcgacgtctg
     5521 catttaggga tgaatcgaat ctataatcta tctgataatc ctaaacaatg ggaagatcta
     5581 gatcagttag gtgcggtgat cgttgttggg actgttacga aagaatcgat taccgccttg
     5641 ttaaaacaaa acatgcaaat agtcgtcgtg gataaccctg acatccagca agaggtcgat
     5701 atggtgtatg cagatcttga acggatgact aaaaccgtac tggaattgtt cttagaaaat
     5761 ggtcataaaa gaatagccta tatcggggga tataaagtcg atatggatga attcggtggg
     5821 aagcagattt ctataaatga aaagaggatg cgtgcctatc agcattttat gatcgatcat
     5881 cacttagaaa aatatatgtc ttatcatcta ggtggctgga cagaaaaaca aggtgaggta
     5941 cttgcgacta atctattaga aaatgaatcc cctcttccta ctgccattct tgtcgggagc
     6001 gatccaatgg caattggtgt ctatcgggca ttgaaacaaa aaaatatcca aattggagaa
     6061 gagattgttg tagcaagctt tgataatatc gagacaatcg caaacctctc ccctggcttg
     6121 accagtgttc aaatcaatgc gaaatcaatt gggcaagcag ctgttcgaat ggcattggag
     6181 cgaattgacg gtatacggga cgaaccaatc attttgactt atcctgcacg attgattgtt
     6241 agggaaagtt ttatcccaag aacaaaaagg tattgaaaga gaggttgtga aaagccgctt
     6301 cgtttcttca tactcaaaac gaaacggctt tttcacaacc tcttacttat acttattcac
     6361 aaaatccaat gtctgctggt aacaattttg cgattctttt agcgtgtaat caaattggta
     6421 ttcatgggta atctcttttt ttgtatctgt ataaaacaag gattgcacgg gtacctttaa
     6481 ttctgtcaac cgattttcta atgcttgacc ttgctcctgg aatgagtatg catttccgtc
     6541 agttatatac gttggcggaa attccttaga aacatggtca gccacactag cttctttcaa
     6601 ttgctcactc gttttccaat cttttgttcc aatcaacgac cacgcaacgg ttttgacgaa
     6661 aaacttcata aatcgatcat ccgaatgctg ctgtgctgtt agcttcaaat caacaggtcc
     6721 gcaataagaa atggttcctt tcagactatc ttttggaagt agctgtttga ttttcatttg
     6781 tttagcatac gcatcattcg tttgtatagc tgcatattgc aatgcgattt gtgaacctgc
     6841 actatctcca ccaaaaaata attgttccat gtctagcaat ttgtcgtctt tttcttcagc
     6901 taataaatct ttgatcagtt cattcacttg aagaacttga ttagggtatt ctgaatcagg
     6961 cgctaattca taattcatcg caaccactgc gatgttggcg tctgaaacta attttgtcgc
     7021 aaattctttg acacccgatt tatctccgcc gacgaatcct ccaccatgta cccaaaatag
     7081 aacaggaaca ggccccttgc tgttttttgg atagtagatg tcataagtat tctctttata
     7141 cttggactca tacgtcaaat ctgttttttt cgccacgttt ttttctgctt gatcgaacgt
     7201 ttttttatca gtgatttgaa cagtatttga aaacatatgg ttgatcaaga atgctccagg
     7261 tctgggggaa agctggaagg caagaaagat tgcaaacgcg atcccaagaa tgattccgaa
     7321 gaaccatccg ataaatttaa gaattttctt tttcataagg ctccctcagt agttagtatt
     7381 aagcattctg attataccat agtgttattt cctatcaagc tctcctagat gatttaatga
     7441 ttttccccaa acttcttctg caatgctttt gacaaaagaa attttttcca ttgttcttca
     7501 aacaaaacat tttcttcttc tgttgaagca aatccacatt gaggacttaa gcacaaacga
     7561 tccaaaggca gatatcgtgt cgcttcgtag atccggtcaa tcacttgctg gtgctcttcc
     7621 atttcgccat ttttcgttac agtcaaaatc taagacaact aatttatctt cagagacttt
     7681 ctctaaaaga acaaaactcc cagcacgttc actatcgtat tctaaataat aggcacggac
     7741 attttcttga gtaaaataat gggtctgcta cgtcgtcatc ccccctgatg ccgccaaaat
     7801 cgaataataa tttccgcgtc aaacatgtat atttagtgtt gaatcatttg agaatatgaa
     7861 aataaaaatc tttttgatca atcagttaat caaattgaaa taacgaaaaa tctgagacag
     7921 aatgacgttc attctgaccc agatttgatt ttgcacaact caacagtcct tattggcaaa
     7981 tcgccaaaat aatgtagact aactaaaaag gctctataat ttatgggact gatgaatcag
     8041 aattgattct tcagccccat ttttatttta ggtatcgccg attgtaaaat taagctagac
     8101 aactaaaaaa gtcatttgtg ctacactcaa aatagttccg accaaagaat tataaggagt
     8161 gagtacaaat gacctatacc catcttacaa cggatgaact tgtaataata gagtcttatt
     8221 tcaaaattaa tcaatctgtt gctaaaactg cccattgctt gaatcgttca agacaaacga
     8281 tccataaagt atatctgttc ttcaagaaag gaaaatcagc cttagaatat tatcaacagt
     8341 ataagaaaaa caaatcaaac tgtggtagac gtccgcttgt tttacccgag gaacaatcag
     8401 aatatattca aagaaaggtt gttcaaggat ggacacccga tgtgattgtt ggtcgtgcag
     8461 cgtttcctat tagttgttct gctcgtacca tttatcgtat gttcaaaaag gggctatttg
     8521 attcttctga cttaccgatg aaaggcaagc gtaaaccgaa tggacatcaa gaaagacgtg
     8581 gaaaacaaac tttccgccgc tctattcatg aacgtgaaaa ggattatagc caattctcaa
     8641 atgagtttgg tcaccttgaa ggtgacacta tcgtaggtct gaaacataaa agtgctgtaa
     8701 ttaccttagt tgaacgatta tcaaaagtta tcatcacatt gaaaccgtgt ggtagacaag
     8761 cgattgatat tgaaaaaaaa ttaaatcaat ggtttgaatc tgtaccgaaa aacctattca
     8821 aatccatcac ttttgattgt ggaaaggaat tttcaaattg gaaacagatc agtaatgtca
     8881 atgatattgc catttatttc gctgatccag gaacgccgtc tcaaagaggc ctaaacgaga
     8941 attctaacgg attgttacgt agagatggtt tattgaaatc tatggatttc aattcagtag
     9001 atgaattttt tattcaatct gtcgcatcta aacgaaataa tattcctaga aaatcactgg
     9061 attatcgaac acctttggaa gtatttttga gttacgtaag tattgatgat ctgtctaact
     9121 taatttgaca attaag
//
LOCUS       DAZUJR010000099         8971 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.101, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000099 DAZUJR010000000
VERSION     DAZUJR010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8971)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8971)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8971
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.101"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            278..786
                     /locus_tag="ACG804_002490"
                     /pseudo
     CDS             278..786
                     /locus_tag="ACG804_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305710.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
     gene            879..2041
                     /locus_tag="ACG804_002491"
     CDS             join(879..1155,1155..2041)
                     /locus_tag="ACG804_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFS4833376.1"
                     /translation="MSRRQRRTYSKEFKQQVVDLYLAGKPRAEIIRDYELTTSAFDKW
                     VKQAQTTGSFQEKDNLIPEQVELIALRKKNKQLEMENDILKQAALILGPKRQVIDTNK
                     HKYSISAMCKVLNISCQTYYYQAKPVEDESELEELVQEEFIRNRKAYGTRKLKQCLAN
                     LGLQVSQRRIGRMMKQRGLRSTYTLAHFKFHSSTCNEAKTANILDGTFLQEKSLEAIV
                     TDLTYVRVGKKWQYICLILDLFNREIIGYSCGEKKDATLVKEAFAKIPYSLNNVQLFH
                     TDRGKEFDNQTIDEILWAFNITRSLSKKGCPYDNAVAESTYKSVKVEFVHQYRFETLA
                     NLRLELFDYVHWWNTIRLHGTLGYETPISFRQQRLAQRILDNELGCDTGGEAP"
     gene            2321..3301
                     /locus_tag="ACG804_002492"
     CDS             2321..3301
                     /locus_tag="ACG804_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4833377.1"
                     /translation="MKKIGIREVAKEANVSPTTVSRVLNDRGYLSEETKRKVFDAMKK
                     LEYYPNELARALFKNETYTVGLIFPTITNPFHAELIQDIEFELSSRGYKVLLCNSLNN
                     PTKEKEYLTMLRKNQVDGIIVGTHNKDIADYDIPGLPIVAIDRSLGENTVTVSCDNYR
                     GGELATQLLVNHGCQNILCIRGDSKIKLPANSRTLAYKDVLNKFMLEPLVLEVPFVKE
                     INEKNEIIKTYLETHPNIDGVFAGDDLLASLAINNLGSSGKRVPKEVKVIGFDGAQQT
                     LIYNPELSTIQQPIDQISKVAVKKLLNMIKGEKETDELSLPVKLIKKNTA"
     gene            3423..4841
                     /locus_tag="ACG804_002493"
     CDS             3423..4841
                     /locus_tag="ACG804_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HFS4833378.1"
                     /translation="MEKLLIKSNNHQLYYQPKDVWVGDVMPYGKEGKFFIYHQRDTRN
                     PVPFGEPFGWALATTKDFVHFEDFGESLLRGDDNERDQFIYAGSVFEANGKVHAFYTG
                     YNREFLAQGKTSQVLLHAESDDFVHWEKSETALELEPQEGYDIRNWRDPFVVWDDEKE
                     EYLLILGARKGQDKHLQTGRLVEFTSKDLTNWEFKGDFWAPGLYTMFEMPELFKIGDW
                     WYLVYSEYSDGNKILYRMSQSLEGPWIKPKDEAFDGRAYYAGRTAYDGKRRVLFGWVP
                     TKDQENDKNNYLWGGTLVPHEVYQKEDFSLGVKPIDEVWNAFINLHDIADVEIETADT
                     REEVTLVKNSGTLFNLETTISFDENLSDFSLRLYKNLETDESYEYRFNLDEGRLTFDK
                     NPCYPWFQYMDKGLIRPISLKPNQSYKLKVIVDDNIMTLYIDGIALNARVHGCFGQAI
                     TITATNGSMTAINTKFSNEIKK"
     gene            4912..6381
                     /locus_tag="ACG804_002494"
     CDS             4912..6381
                     /locus_tag="ACG804_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFS4833379.1"
                     /translation="MDYKKIAEDVLENVGGKENISSATHCITRLRLILKDKSKANMEM
                     LEEIEGAKGVLFNSGQLQVIFGTGIIEKVYKEFVELTGAKEVSVSEMKDEGVNNSGNR
                     LQRAFKVFSDIFIPIIPAFIGAAMVLGIRSLITTPGMFGMDGSFADHNVFLNDLSKFL
                     GIIATTFDYLPVLVMYSATKRFGGNPILGLLVGFVMIHPGLANRNDFVMGTIKPDYWH
                     LFGLSIPAVAFQGGVFPAILTSWFLAKVEKITNKYSPQVLAYILVPTVTIVLANFALF
                     LVFGPLGNFIGNVLGGIIDFLYMKMGAFGAFVFAGALQPLVVTGTQHAIQGIEANLVA
                     TTGFNYIQPIWSVSIIAQGGGCIGMYLLFKKKSKDRDIAISSFIPTLVGITEPAIFAV
                     NLKYSIVPFVCSFIGAGFGGAFMKIFDVKAIGQGLTVLPGLTIANPVLPYIFGNLIAF
                     ILPIIFILAYDKYKVFIPEAKHRKFAEKTDSKKLPVQVK"
     gene            6391..6858
                     /locus_tag="ACG804_002495"
     CDS             6391..6858
                     /locus_tag="ACG804_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFS4833380.1"
                     /translation="MLNFFRKNEISVVAPATGVFEKLEKLSDPVFSKGMMGQGFAIDA
                     KNETIVSPIDGFVSSIFPTKHALGIKTKSGIEILVHVGIDTVELNGEGFDIKVQEGQK
                     VKAGDILMTINFVVFEKNHKTKDVIVVFPDYQDEIFIPKLEEVKQGQELFVLG"
     gene            6894..7766
                     /gene="scrK"
                     /locus_tag="ACG804_002496"
     CDS             6894..7766
                     /gene="scrK"
                     /locus_tag="ACG804_002496"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HFS4833381.1"
                     /translation="MVFGAIEAGGTKFVCAIGDKDLNIFEKVSFPTTTPKETMNLVLD
                     FFNHHKDDLEGIGVGSFGPIDIHCESKTYGFIKSTPKLAWQDFDFIGSLKKQLNIPTA
                     WTTDVNASCYGEYVSGNGRGLSSVVYYTVGTGIGGGAIQNGNFIEGFSHPEMGHMLVK
                     RHNKDNFSGTCPFHGDCLEGLAAGPAIERRSGKKGQEVTENDVTWEIEAYYIAQCAYN
                     TTLMLSPDVIIFGGGVMKQKHLKKKVQDKFIELINGYVAIPDVDNYIMTPKLLDNSGI
                     VGCLALARDVKEKS"
     gene            7847..>8971
                     /locus_tag="ACG804_002497"
     CDS             7847..>8971
                     /locus_tag="ACG804_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFS4833382.1"
                     /translation="MKKKMKDEVLEYIKNNLKYYDFSAQDIAMKFCIKRNVASHYLNQ
                     LFSDGKLLKNDSVRPVMFKYNQQKPKDCFSKFIGADISLKSTIDKCKATVMYPPNGLP
                     LIIKGNSGVGKSFLASLIYQYALDRKVIHNDAKFVVVNCADYANNPELLSAVLFGYKK
                     GAFTGAEKDTAGMLSSANGGYLFLDEVHNLSAENQEKLFLLMDSQKYRKLGESVQWEY
                     ANVRLILATTEDKNTSLLATFRRRIPAEITLPDYNNRSTSEKIQLLFEFLKDEAITID
                     SKIFCSIELFTDLLSKTFEGNVGELRNEIKLLCAEGYLGNKRKSSIYLGDKLDSGFWI
                     DPEISIDLKKMFLKSLSEIDLIELFQNHISIEESMSQLRDR"
BASE COUNT         3092 a         1333 c         1802 g         2744 t
ORIGIN      
        1 ttttttattt gtctcgctta attatacaaa cggcgtgata aaaaacgaga aatgaattat
       61 aggtttagac ctttatcatt tctcgtttta ttttattgta tcaaggctct atcataagtg
      121 gtaaaatcta cttttaaatc acatgtaatc attgataagt ccagtgtttt agcggataat
      181 cagcttttta tttatttttt cttataaatt tgataaatag aaattagtat agccctaaac
      241 aaattatttg tgttttattg tttagggcta tactatattg gtacaaggaa tagaaagagg
      301 tgtttatgtg gttgataaaa ttcagtttaa tcaagttata gaagaattca tcaaagtaaa
      361 taatttaatg acccatattc aaaaacgacc aatcagaata actaatgatc taaaactcag
      421 tacgagtatg attcatttga ttgatgtgat tggaaattat cctgaaacta gtattacgga
      481 attagctgat cgattaggcg ttaccaaagg agctgtatcc caacagattc ccactttaga
      541 gaaaatgaat cttataagca tttctcaaaa aaaggaaata agaaaactaa acttgtatcg
      601 ttaacaaaat atggtcgaaa ggtgtacgaa tcacataatt atttacatga agagctttat
      661 agctcaataa atgaagcgtt agaatcattc tcaccagacc aaatttcaac cattaaacag
      721 attctagaaa aagtatctta tacaatcaat gaatatcaag taagtctgac aagaaaggaa
      781 gattgacatg aaaaaaatga tttttgaatc ggctacacta gactagacag aaaaaataag
      841 gtgtgtaaaa taaatgaaaa cacactggag gaatttttat gtcaagacgt caacgtagaa
      901 cctattcaaa agaattcaaa caacaagtcg tcgatcttta tctcgcagga aagccccgag
      961 ctgaaatcat tcgagattat gagctgacta cctcggcctt tgataagtgg gtcaagcaag
     1021 cgcaaactac tggctcgttt caggaaaaag ataacttgat ccctgaacaa gtagaactaa
     1081 ttgcattacg aaagaaaaat aaacagcttg aaatggagaa tgacatttta aagcaagcgg
     1141 cgctgatatt gggacgaaaa gacaagtaat tgataccaat aagcacaaat actcaatatc
     1201 agcgatgtgt aaagtgttaa acatctcttg ccaaacctat tattatcaag ccaaaccagt
     1261 tgaagatgaa tcagaactgg aagaactcgt tcaagaagaa tttattcgca atcgaaaagc
     1321 ttatggtacc aggaagctga agcagtgctt ggccaatcta ggtcttcaag tgagtcaacg
     1381 cagaatcggc cgtatgatga aacagcgtgg cttgcgttca acatacacat tggctcattt
     1441 caaattccat tcttctactt gtaacgaagc caagaccgcc aatattctag acggaacctt
     1501 cctacaggaa aagtcattag aagcgattgt aaccgacctt acctatgttc gtgttgggaa
     1561 gaaatggcag tatatctgcc tgattcttga tttgtttaat cgagaaatca tcggctattc
     1621 atgcggggag aagaaagatg cgacgttagt caaggaagct tttgcaaaga ttccgtactc
     1681 gttgaataat gtacaacttt ttcacacgga tcgtggaaaa gaattcgata accagacgat
     1741 tgacgaaatt ttatgggcct ttaatatcac gcgttcctta agcaaaaaag gctgccccta
     1801 tgataacgcc gttgcagaat ccacctataa atctgtcaaa gtagaattcg ttcatcaata
     1861 ccgctttgag acattggcta atttgcgatt agagctattt gattacgtcc attggtggaa
     1921 taccatccgg ctgcacggca cgttaggcta tgagacaccg atcagttttc gacagcagag
     1981 attggcgcag cgaatccttg ataatgagct cggatgtgat accggtggcg aggcacctta
     2041 attatttgaa tgagcttctg ccttagagaa tcagattcga ggaggctcgt tgtcaagggc
     2101 agtcggaaca ccagcagcaa gcttacgcaa taccttataa tttttgtcaa aaaaagtgtt
     2161 gccattccac atatatcttt aaacagctat tgccagataa aaataaatga tattatatat
     2221 ataaatactt atccgaaaag gggaatgaga gagtcaaggt tcttggaatg tcgaatagtc
     2281 gagtaggtag attttctatc tacaaccttg ttgtttaaaa atgaaaaaaa ttggaattag
     2341 agaagttgcg aaagaggcaa atgtttctcc tacgactgtg tcgagggtat tgaatgatcg
     2401 tggatatttg agtgaggaaa caaaaagaaa agtttttgat gccatgaaaa aattagaata
     2461 ctatcctaat gaactggcga gagcactttt taaaaacgaa acatataccg taggtttgat
     2521 ttttcctaca attactaatc catttcacgc tgagttaatt caagatatcg agttcgagct
     2581 ttccagcagg ggatataaag tgttgctgtg caatagctta aacaatccaa caaaagaaaa
     2641 agagtacttg acgatgttga gaaagaatca ggttgatgga attatagtag gaacgcacaa
     2701 taaagatatt gcggattatg atattccagg gctacctatt gtagcgattg atagaagtct
     2761 tggtgaaaat acagttacag tatcttgtga taattacagg ggtggggaat tagctactca
     2821 actacttgta aatcatggct gtcagaatat actgtgtatt cggggagata gtaagataaa
     2881 gctacccgcg aatagtagga ctttagcata taaagatgtt ttgaataaat tcatgctgga
     2941 accgttagtc ctagaagtac catttgtaaa agaaatcaat gaaaaaaatg aaataattaa
     3001 gacatatctg gaaactcatc caaatattga cggggttttt gcaggagatg atttattggc
     3061 ttctttggcg attaacaact taggaagttc gggcaaaaga gttccaaaag aggttaaagt
     3121 gattggattt gatggagctc aacaaacatt gatttataat ccagaattat caactattca
     3181 acagcctata gatcaaatat ctaaagtagc agtaaaaaaa ttattgaata tgattaaggg
     3241 cgaaaaggag acggatgaac tttcacttcc agtaaagctc ataaaaaaaa atacagcata
     3301 agttaaatcg gcgaaaaatt ccttcgtcga tttaaaaata tttttatgaa acgggttgac
     3361 atatgaaacg ggttgacata tattagttgt gaagataaaa accttttcac tggaggaaga
     3421 aaatggagaa attattaatt aaaagcaata atcatcaact ttactaccaa cctaaggatg
     3481 tttgggtcgg agatgttatg ccttacggga aagaaggaaa attctttatt tatcatcaac
     3541 gtgatactag aaatccagtt ccttttggag aaccgtttgg ctgggcttta gcaactacga
     3601 aagattttgt tcattttgaa gactttgggg aatctctttt aagaggggat gacaatgaga
     3661 gagaccagtt tatctacgct ggttctgtat ttgaggcaaa tggaaaggtt cacgcatttt
     3721 atacagggta taatcgtgaa ttcttagcgc agggaaagac atctcaagtg ttgcttcatg
     3781 ctgagagtga tgattttgtt cattgggaaa aatcagaaac agcattggag ttagaaccac
     3841 aagaagggta tgatattcga aactggagag atccatttgt cgtttgggat gatgaaaaag
     3901 aagaatattt gctaatttta ggggcgcgaa agggtcagga taaacatcta caaaccggac
     3961 gtttagtgga atttacatca aaagatttaa ctaattggga attcaaaggt gatttttggg
     4021 ctccgggatt gtataccatg tttgaaatgc cagaactttt caagattggt gactggtggt
     4081 atcttgtcta ttcagaatac tcagatggaa ataaaatact ctatcgaatg agtcaaagtt
     4141 tggaaggtcc ttggattaag cctaaagatg aagcttttga tggacgggct tattatgcag
     4201 gtagaacagc ttatgatgga aaacgtcgag tcctatttgg atgggtacca acaaaagatc
     4261 aagaaaatga taaaaacaat tatttatggg gaggtacttt ggttcctcat gaagtctatc
     4321 aaaaagagga tttttcactt ggggtaaaac ccatagacga agtgtggaat gcattcataa
     4381 atttacatga tattgccgat gtagagatag aaacagcaga cacaagagaa gaagtaacgc
     4441 ttgtcaaaaa tagtggaact ttgtttaatt tagaaacaac aatttcattt gatgagaatc
     4501 ttagtgactt ttcactgaga ttatataaaa accttgagac agatgaatct tacgaatatc
     4561 gcttcaattt agatgagggg cgtcttacat ttgataaaaa cccttgttac ccttggtttc
     4621 aatatatgga taaaggactt attagaccta tatctttaaa gcctaaccaa tcttataaac
     4681 taaaagtgat tgttgatgac aatataatga cactttatat tgatggaatc gctcttaacg
     4741 ctcgtgtaca tggttgtttt ggtcaagcaa ttactattac agcaacaaat ggatcaatga
     4801 ctgcaataaa taccaagttt tcaaatgaaa taaagaaata ataaacgtca atcatgtggc
     4861 aggtctgaaa atcaaacatg acctgtcaca tttaaaaggg aggataaatg aatggactac
     4921 aaaaaaattg ccgaagatgt attggaaaac gttggaggaa aagagaatat ctcaagcgct
     4981 acacactgca ttactcgttt acgtttaatt cttaaagaca aaagcaaagc gaatatggaa
     5041 atgcttgagg aaatagaagg tgcaaaaggt gttcttttca atagtggaca gttacaagta
     5101 attttcggaa caggtataat tgaaaaggtt tacaaagagt tcgttgaatt gacaggagct
     5161 aaggaagtat ccgtttctga aatgaaagac gaaggagtca ataattcagg aaatagactt
     5221 caacgagctt ttaaagtttt ctcggatatc tttattccga tcattccagc ttttattggg
     5281 gcagcaatgg ttttaggaat tcgttcgttg attaccactc ctggaatgtt tggaatggat
     5341 ggctcattcg ctgatcacaa tgtattccta aatgatttat ccaaatttct gggtattatt
     5401 gcaaccacat ttgattattt accagtttta gttatgtatt ctgcaacaaa acgttttggc
     5461 ggaaacccta ttttaggatt acttgtagga tttgttatga ttcatccagg actagccaat
     5521 cggaatgatt tcgtcatggg aactataaag cctgattatt ggcatttatt tggattaagc
     5581 attccagcag ttgcgtttca agggggtgtt tttccagcaa ttttgacttc ttggttttta
     5641 gcaaaagttg agaaaattac aaataaatat tctcctcaag tacttgctta cattttagtc
     5701 ccaactgtga caattgttct tgccaacttt gcactatttt tagtgtttgg tccattgggg
     5761 aattttatcg gtaatgtttt aggtggaatc attgatttcc tatatatgaa gatgggtgcc
     5821 tttggtgctt ttgtttttgc aggcgcgtta caaccattag ttgtaacagg aacacaacat
     5881 gctattcaag gtattgaggc aaacttagtc gcaacaactg gattcaatta tatccaacct
     5941 atttggtcag tttcaattat tgcccaaggt ggcggttgta ttggtatgta tttactcttt
     6001 aagaaaaaat ctaaagatag agatattgcg atttcaagct ttattccaac actggtaggt
     6061 attactgaac cggctatctt tgctgttaat ttgaaatatt caatcgttcc ttttgtttgc
     6121 tcgtttattg gtgctggttt tggtggagca tttatgaaaa tttttgatgt aaaagccatt
     6181 ggacaaggat tgactgtatt gccaggtctg actattgcta atccagttct tccttatata
     6241 tttggtaatc tcatagcatt cattttacca atcattttta ttctcgctta tgataaatat
     6301 aaagtgttta tccctgaagc taaacaccgt aaatttgcag aaaaaactga ctcaaaaaaa
     6361 ttgccagttc aagtaaagtg agatgagagc atgttaaatt tttttagaaa aaatgaaata
     6421 agcgttgtag cacctgcaac cggtgttttt gaaaaactgg agaaattaag tgatccagtc
     6481 ttttcaaaag gaatgatggg acaaggattt gcaattgatg caaaaaacga aacgattgta
     6541 tctccaatcg atggttttgt ttcaagtatt tttcctacaa aacatgcctt aggaataaaa
     6601 acaaaatcag gaattgagat acttgttcat gtaggaatag atacagttga gctaaatggt
     6661 gagggatttg atattaaagt tcaagaagga caaaaagtta aggctgggga tattcttatg
     6721 accattaatt ttgtagtttt tgaaaagaat cacaagacta aagatgtcat tgttgttttt
     6781 ccagactacc aagacgaaat tttcattccg aaacttgaag aagtaaaaca aggacaagaa
     6841 ttgtttgttc ttggctaatg ataagtaatt aataatagaa tcgaggaaaa tgtatggttt
     6901 ttggggctat tgaagctggt ggaacaaaat ttgtttgtgc cattggagat aaagatttga
     6961 acatatttga aaaagtcagc tttcccacga ctacacccaa agaaacaatg aatttagttt
     7021 tagatttttt taatcatcat aaagatgatt tagaaggtat cggagtggga tcgttcggtc
     7081 ctattgatat tcattgtgaa tctaaaacgt atggcttcat taaatcaacg ccaaaacttg
     7141 cttggcagga ttttgatttt attggaagtt taaaaaagca acttaatatt ccaactgctt
     7201 ggacgactga tgtaaatgcc tcttgctatg gtgaatatgt ttctggaaat ggcagaggcc
     7261 tttcaagtgt tgtttactat accgtaggaa cgggcatagg aggtggcgct atccaaaacg
     7321 gaaacttcat tgaaggtttt agtcatccag aaatgggaca tatgcttgta aaacgacaca
     7381 ataaagacaa cttttctggg acatgtccat tccacggaga ctgtttagag ggcttagctg
     7441 ctggtccggc aatcgaaaga agatcaggga aaaagggaca agaagtgact gaaaatgacg
     7501 ttacttggga aatagaagct tattacattg ctcagtgtgc atataataca acattgatgt
     7561 tatcacctga tgtcattata tttggtggcg gagtaatgaa acaaaaacac ttaaaaaaga
     7621 aagtacaaga taagtttatt gagttgatca acggatatgt cgctattccc gatgttgaca
     7681 attatattat gacaccaaaa ttgttagata attctggtat tgtaggttgt ttagctttag
     7741 caagagacgt taaagaaaaa tcttaatttg gaaaaaagat cgtctcgact atttgtttgg
     7801 ttgatgcgat ctttttttca attagtaatt gaagggacgc ctaaaagtga aaaaaaaaat
     7861 gaaagatgaa gtattagagt atatcaaaaa taatttaaag tattacgatt tttctgctca
     7921 agatattgca atgaaatttt gtattaaaag aaatgtcgct tcccactatt tgaatcagtt
     7981 attttcagat ggaaaattac taaagaatga ttctgttaga ccagtaatgt tcaagtataa
     8041 tcaacaaaag ccaaaagact gcttttctaa gtttattgga gcagacatat ctttgaaatc
     8101 cactatagat aaatgcaaag ctactgtaat gtatccccct aatggcctcc cattaataat
     8161 aaaaggaaac agtggcgttg gaaaaagttt tttagcaagt ttgatctatc agtatgctct
     8221 tgatagaaaa gtaattcata atgacgcaaa atttgttgtt gtgaattgtg cagattatgc
     8281 aaataatcca gagctattgt cagcagtttt atttggatat aaaaaaggag cctttactgg
     8341 ggctgaaaaa gatactgcag ggatgctatc ttctgctaat ggaggatacc tttttttaga
     8401 tgaggttcac aatctaagtg cagaaaacca agagaaattg tttcttctta tggattctca
     8461 aaagtatcgt aaacttggtg aaagtgtgca atgggagtat gcaaatgttc gccttatctt
     8521 agccacaaca gaagataaaa atacctcttt gttagcaact tttagaagac gcatcccagc
     8581 tgaaatcact ctgccagatt acaataatag aagtacatct gaaaaaattc aattattatt
     8641 tgaatttctt aaagacgaag caattacgat tgattcaaaa atattttgtt cgattgaact
     8701 ttttactgat cttttatcga aaacatttga aggaaatgtt ggagaattga ggaatgaaat
     8761 caagcttctt tgtgcagaag gttatttagg aaataagaga aagtcttcaa tttatttagg
     8821 ggacaaacta gacagcggtt tttggataga tccagaaatt agtatagatt taaaaaaaat
     8881 gtttcttaaa tcactttctg aaattgattt gattgaactt tttcaaaatc acatttcaat
     8941 tgaagaaagc atgagtcaat taagagatag a
//
LOCUS       DAZUJR010000100         8784 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.102, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000100 DAZUJR010000000
VERSION     DAZUJR010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8784
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.102"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(382..2763)
                     /locus_tag="ACG804_002498"
     CDS             complement(382..2763)
                     /locus_tag="ACG804_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HFS4833383.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(2753..3400)
                     /gene="recU"
                     /locus_tag="ACG804_002499"
     CDS             complement(2753..3400)
                     /gene="recU"
                     /locus_tag="ACG804_002499"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HFS4833384.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            3464..4003
                     /locus_tag="ACG804_002500"
     CDS             3464..4003
                     /locus_tag="ACG804_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HFS4833385.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            4093..4512
                     /gene="gpsB"
                     /locus_tag="ACG804_002501"
     CDS             4093..4512
                     /gene="gpsB"
                     /locus_tag="ACG804_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HFS4833386.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            4534..4901
                     /gene="rnpB"
                     /locus_tag="ACG804_002502"
     ncRNA           4534..4901
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACG804_002502"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            5110..6276
                     /locus_tag="ACG804_002503"
     CDS             5110..6276
                     /locus_tag="ACG804_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HFS4833387.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            6322..7818
                     /locus_tag="ACG804_002504"
     CDS             6322..7818
                     /locus_tag="ACG804_002504"
                     /EC_number="3.4.17.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HFS4833388.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            7899..8582
                     /locus_tag="ACG804_002505"
     CDS             7899..8582
                     /locus_tag="ACG804_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFS4833389.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            8591..>8784
                     /locus_tag="ACG804_002506"
     CDS             8591..>8784
                     /locus_tag="ACG804_002506"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833390.1"
                     /translation="MTEVVSSKIFRIIFRKSYFWNTVYQEVVSLPFSSESQGTISKNS
                     FSCLMNIVTCDSELAGEHRL"
BASE COUNT         2774 a         1586 c         1855 g         2569 t
ORIGIN      
        1 gatggtgcag acaaattatg ataattaagc atactatcag ataactcaaa atgaagcctt
       61 ctttcaaaaa attattcaaa accatatatt gtatttttta tttgataata acaatgggat
      121 tattaagaag tggcactaaa taaaagacta gtgtgtattt agccgattta attataaaca
      181 agtaaatgga taaagtatat gtaatgataa aagaaaaatg gattttctaa tttttaagct
      241 aaatgttaga tcacacatgt atatgctgga tagtcttata aaaaatcatg taatacagct
      301 tggtacatga tttttatttg tagctgtttt ttacatagac acaaaaaaga aaccacgctt
      361 gtagacgtgg tttctttttt actatctgtt tccagaagct gaggtgctgc tggatggtgt
      421 atggtcattt gcagcatccg ctccgctagt tgctggctca ctggaagaag caggaggagc
      481 agatgaagac ggtgtcgagc tttcttcgga tgaagaagaa ggaaccgttg ttgaagacgc
      541 tggctcgctt gtttctgctg tcgtgctttc ttttgaggac tcagcagttg attcgctttg
      601 actagtagag ctagagcttt gagtcgttgt ctctgttgtt gagcttccag gagtctggac
      661 atagctggaa gatggaatag ttgttgatgg tgtaattgca ttcgatctag ctgtatattg
      721 atctttgtag tacagttcac cgcccacacg aattaatccg cttggcatct cccagtctgt
      781 atttgtcacg ttagctgaaa catactgcat aagctcgcga taaacatcag aggctacgtg
      841 tgacgattct gaagtgacag gcgtcatttt tttattgtaa cctgtccaca cggaaatcga
      901 ataatttggc gtatagcccg caaataggat atctggatac accccagaag aaataccaag
      961 ttttgcatac tcgtcatctg tgtaattgga tgttccggtc ttaccggctt gatataaccc
     1021 agcgatttgc gcattcgtac cagttccttc agtgatcgta tcttttaaaa tgtctgtgat
     1081 catataagct gtttctggag acatggctgt ttttccatct ggctcataag tttcttctgt
     1141 tccgtcttgg aagacgattt tattaacata ttgaggtttg taataagtcc ctccattggc
     1201 gaaagccgca taggctgctg ccatttttaa ggaagaagct ccgtattttg tcccatcttg
     1261 ttcttccgta ttactagaga tcgcattcga ttgatggatc gtactgtatt cgatcccaag
     1321 attttttaag aaagaagcca ctttatctga accgacttca ttgaataatt tgactgctgg
     1381 aacattacgg gataagtaaa gtgcttggcg taaagtaatg gtgcccatat attgattatc
     1441 ccagtttcct acaggagtcg aagtcccttc atagttatac ggtgcgtcag taatagtttt
     1501 tccagtagaa tatttcaaat attcaaaagc tggtccgtaa tctgtgacag gtttcatcgt
     1561 agaaccaaaa tcacgggaag tattcactgc taagttgttg cctaaagtta cgtcttctgc
     1621 gatgtgacgt ccgccaatct gggcttttac tttcccggta ttggtgtcga taagggtgga
     1681 ggcaacttgc atctcgtcgt ctgggtaaga gacatactga tccgtgttga cgatatcata
     1741 tagtttcttt tgggcgtcca gatccaaatt cgtataaatc tctaaaccgt ctgtgtagac
     1801 attcttatct gttttttctt gtacttcatt gatgacttct ttgacataat tatcgacgat
     1861 cttagtattg tcatcggatt gagttagttc ttgcagacca tccgttaccg gtacattaac
     1921 agcttgatca tattctgttt gagagatttt ttcgttttga agcatcgtat acaaaacagt
     1981 atctcgtctt ttcttcgcct gatctggata aacataagga tcataggcgg aaggggcttg
     2041 aggcatccca gcaagcaatg ctgtttgcgg taaagaaagt tctgataatt tcttaccaaa
     2101 gtacatctca gaagctgtct ccatcccgta caagccgttt gacatataca ctttatttac
     2161 gtagtaggtc aagatctctt gtttcgattt tttttgttcc aatcttacag ccatccacgc
     2221 ttcttgggcc ttgcgtttca gagtctgatc ctcggcactg gtggagaaga aggaaagttt
     2281 gatcaattgc tgtgtcaaag tacttccgcc ttgcagtccg ccagaggtaa agttagagag
     2341 ggcagaaccg atgatccgaa tagggtcaac cccgatgtgt ttataaaaac ggcgatcttc
     2401 taccgacacg atcgcatctt ctaatgtttt cggtaattca ttcgcagaaa ttttttcacg
     2461 cttttctgcg cctaaatctt cgaatagttc gccatcttgt gtatatagtt tggaagatac
     2521 ggtagcgtct aattttttat ccgtcaattc gggcgcatct tttgcgtaat accagaaaag
     2581 tcctacacct gctaaaaaga ggatacagaa aaatgagagt attcctaaaa ggatcttgat
     2641 aaataatcct tttttatgtg ttccagagga ctttccagaa cctttgccag aattcttctt
     2701 cacactcttt ttaggagtag gctgtttctg tcgtctagag cttctagttt gttcatttgc
     2761 cattcttgct ttctccttca atagataatg ttgataaata gaagtcaacc gcgtccaaat
     2821 aaggaatccg cggagaaata ccagttttga tctctattcc tagttcttcg atcaaagata
     2881 aaggtagtga tttgcgtcct ttttcctttt gggcgtccca gtaagcaatc aaatgaacac
     2941 tattcaaata aaaacagcgc ttcaaagacg aaaaccataa caagacaaag cagaccccat
     3001 tttgttcgag gcatgctttc atatgttcga tttgatgggc atggaagttt ttaaagggaa
     3061 aagatgtttt gttcttggtt tcttttgctt caaagtccaa gtaaaagcct cgatagacgc
     3121 cattatagtc tgtagttgag gcttgggtaa agtaggcttc cttgatcaca gcagcacttc
     3181 tcttaggata gtctactttc acgatttgga taggggtagg ctttttatgg ataaccgcca
     3241 acccgcggga aagataatat ttattacttt cattgattgc ttcttcaaag cgcatccccc
     3301 gattgccgaa ttcagtgatc tgatttcttt tttcttgaat tttttcgacg ggagaggcat
     3361 tcttataata aggttggcca tttggatagc gcaataccat ctttaatcac actcctaggc
     3421 cacattatag caaaaaagcg gatagaaaga aaaggaatct gagatggata agtcaaaagt
     3481 aatctatgtg tctgggtatc gaagtttcga actcggtgtt tttaaagaaa atgatcctaa
     3541 aatccaagtt gttaaaaatg ttttaaaaaa agaactccat cagttagcag aagaagggct
     3601 ggaatgggta cttgtcagtg ggaatttggg cgtcgaacta tgggctgtgc aaatagtagc
     3661 ggaattgaaa gaagaatatc cggaactatc tcttggtatt ttgtatcctt tttctgattt
     3721 tggtaataac tggaatgaag ggaaccaaga aaaaaaacaa ttagcagaac aattagcaga
     3781 ttatgtcgaa gctgttagcc atcaacccta ccaatcacct agtcagctaa agaatcacac
     3841 tcgttttata cttgagcata cagtgggctg tctgctgatc tatgatgaag aattccctgg
     3901 aaaaacgaag tatttttttg aagatgcaca gaattaccaa gcagatcatc cctacgaaat
     3961 tcggctgatc agtatggacg atcttcaaaa ttttagtgaa taatcgatat tgtgtttgat
     4021 ttatcaactt ttttcctata caatgaaaaa ggtagaaatg ttattacgta aatgaaaact
     4081 agaggtgtaa atatggcgaa tttggtttat agtcctaaag acattttaca acaagaattc
     4141 aaaacaaaaa tgcgcggcta tgatcccgtt gaagttgatg aattcttaga caatatcatc
     4201 aaagattatg aaacttacag caaagaactc cttgctttac aagaagaaaa cgatcgattg
     4261 agtgcaaaag tagctcaatt atctaaaact caaggagcag ctcaaacacg cgtgcaacaa
     4321 acagaggcac caaagagcgc agcagtgacc aattttgata tcttaaaacg cttgtcaaat
     4381 cttgaacgtg aagtatttgg taaaaagctt gatcaacaag caagtgcagt caaaccagca
     4441 caacctaatc caaataacta cacaaatgca gacacaagct tagatgataa tgaaaaaaca
     4501 cgtcaatttt aatttttgat taatgaattt gcggttttcg ggtaatcgcg gtctgacttg
     4561 atcaggctga ggaaagtcca tgctcgcaca ggctgtgatg cctgtagtgt tcgtgcttag
     4621 cgaaaccata agctaaggta ctctttggag taacggcagg aaaacaagct aaggcttcgg
     4681 ctatgcttaa gtatccttga aagtgccaca gtgacgaagc ggctggggaa acccatccgg
     4741 tggaacgcgg taaacccctc gagcgagcaa cccaaacaat ggtaggggcg ctttttgtct
     4801 ggaagaagaa caggacaaaa aggcagtata actgcagata gatggttacc gctttgtttt
     4861 ttctccctgg aaaagcaaag tacagaacat ggcttataga aaaccgcaaa catcagggaa
     4921 ttaggtcgtg acaaaagtaa tgcgttataa gaaacaagaa aaacatttga aagctatttt
     4981 tcaatacttc agatgaatcg ttcttattac aaaacaaact tttgtatcac cggttattcg
     5041 gaatttgagt aaaagtgtgg ggtaggactg atgtcccacc tccttttttt ataaataagg
     5101 agattgtgta tggaaaaaaa caggaagttc aacctcgtcg caactgcggc aagcgggcta
     5161 gaagcactgg ttggtaaaga attaagagat cttggaatcg aatgccaagt tgagaacgga
     5221 cgtgcacgtt ttgaaggaac aatggaaacg atcgctacag ctaatttatg gttacgtaca
     5281 gcagatcgag taaaaatcgt ggttggggaa ttcgatgcgt atacgtttga tgaattgttt
     5341 gaaaacgtaa aagcattgcc ttgggaagat tttcttccac tagatgcagc ttttcctgta
     5401 gctggaaaat cgatcaagtc gaaactatat agcacacctg attgccaagc gatcacaaaa
     5461 aaagcaatcg ttgaacgtct ccgtacctat tatcaccgtc cagcttctgt accactgacg
     5521 gaaactggcg cacattttca gttggaagta gctttgctga aagaccatgt gatggtaact
     5581 ctggatacga caggaccaag tttattcaaa cgtggttatc gcttagaaaa aggtggagca
     5641 ccattgaaag aaaacatggc agcagcactt attatgttga caaattggcg aaaagaccgt
     5701 ccattttatg atcctgtatg tggttcaggt acgctttgta ttgaagcagc cttaataggc
     5761 cataatatcg caccaggatt caatcgtgag tttgcttgcg aatcttggga ttggttcagt
     5821 caagaaatca tggaaaatgt tcgatcagca gccgaagaaa aagcagatta tgatattgaa
     5881 ttagatatta ctggttcaga tatcaatgga cggatgattg aaattgccaa agccaatgca
     5941 gaagaaatcg gattaggctc ttcgattacc tttaagcaac aagcagtcaa agacttcaaa
     6001 acggataaag aatacggggt catcgtggct aatccgcctt acggagaacg tctaggagaa
     6061 gaagaaactg ttcggaaatt atataaagaa atgggcgatg tattccgtcc attaaaaaca
     6121 tggagtaaat atatcttgac tagcgactta gcgtttgagg aattttacgg acaaaaagca
     6181 accaaaaaaa gaaaattgta caatggtgca ttgcgtacgg atctattcca gtattgggga
     6241 actcgtccgc ctagaaaaaa agagaaagac gaataatctt actaattgat tcattcaatt
     6301 ggatgtttgg aggaataggg aatgaaagaa aaagagtttt tacaagaagt aaaagaaatc
     6361 aatcttctac aacaagcttt aggaatcctc gattgggata cacaaacagg tatgcctgaa
     6421 aaagctagtg cataccgaag tgaagtagac agctatcttt acagcattta tttttcaaaa
     6481 aaaatcggtc caaaaatcaa agaagccatt cgctattttt ctgaacatcc ggaagaattg
     6541 tcggaagttg gaactgccgt ttttgccaaa gtaaaagaag agtatgattt ggaacatcgc
     6601 gtaccggaag atcttatgag aaaatataca gctgccgttt cttcagcaca cggacaatgg
     6661 caaaaagcta gagaaacaca acaattttct gattttcaac acgcattgaa tcaaaatatt
     6721 gaattaacaa aacagttgat accttactgg agaaaagatg aaaagacgaa ttatgatgtt
     6781 ttgctgaatc aatacgaacc cgggatgact gtcgaaatcc ttgataaggt atttgatcag
     6841 cttaaagaag gaattctttc gatccgccgt acgctccaag aaaaagggac tgaacctgaa
     6901 acagactttt taaatcggag aatgacgaaa aaacaacaga agagatttgt agtgaaagta
     6961 atcgaacaac ttggttatga ttttagtcgt ggtcgtttag atgacactgt ccacccattt
     7021 atgactggaa ttaatccgaa tgatgcacga atcacgacac gatggaacga aacagatttc
     7081 aaaatggctg tttttggagt gatccacgag gctggtcatg gtatgtatga acaagacatc
     7141 gatgataaat atgcgtatac accggtttat gaaggtacat caatgggtat ccatgaatca
     7201 caatcgttgt ttaacgagat cattattgga agtagtcgca gcttctggaa aaagcaatat
     7261 cctttctttc aagaatgtgc agaaggaaca ttcgatgata ttccttttga caaattttat
     7321 cgttcattga accatacaaa atcaagtttg gttcgtatcg aggcagacag tttgacttac
     7381 cctctccata tcatcattcg ttatgaaatc gaaaaaatga ttttcaatga aggggtagat
     7441 gttgctgaac tacctgaaat atggaatcaa aaatatgaag agtatctggg aatacgacca
     7501 acaaatgatg tggaaggcat cctacaagac gttcattggt caggtgcaag ctttggttat
     7561 tttccctctt atgcattagg gtacatgtat gcggcacaat tacttcattc tttgcagcaa
     7621 gaaatagatg tggaaaatgt tctagcgtca gacgattatt ctccaatcaa aaactggatg
     7681 tcagagcata tccatcaata tggtgcatct agaaaaccaa atcaattaat catggatgca
     7741 acacatgaac cgcttaatcc gcaatacctg atcgactata tgaaagacct gtattttaat
     7801 gtatatcagg taaaataaaa tacaatttac aaagatagct gaaattcatc taatctatag
     7861 atgttttcag ctatttactt aagaaagaag tggaacgaat ggataaatta caagtgatcg
     7921 ctgattatag tatggaccaa ttagcgcatg atcaaacagg acatgggagc gatcatacca
     7981 aaagagttgt caagttagct gaaaaaattt tggagacgga accgcaggca gaccgctttg
     8041 tgacgcttgc agcagcttac ctacatgata cgattgatga taaagtcgtt aaaaatgaga
     8101 acgaggcaaa gcaacagctt cgtgtattcc ttcgctcttt gccaatagta gaggaacaga
     8161 tctcgatgat tttttccatt atcgaaaata tgtccttttc taaaaatctc tctgaagcgg
     8221 ccgaactatc tctggaaggt aagatcgttc aagacgctga tcgtatcgaa gcattaggag
     8281 caatcggcat tttgcgtact gcttatttcg gcggtggaca tgggcacccg atttttgatc
     8341 ctgaactgta tccgcaaaca ttcaaggaca aagaaaatta ccgaaaaggc acgacagtga
     8401 tcaatcattt ttatgaaaaa ctgttcttgc tgtctgataa aatgaatact gattacggat
     8461 atgaagaagc caaacgaaga gaaaccttca tgcgtgaatt cttagaagaa ttttttctgg
     8521 aatggtctat tgacgatgaa aattttactc cagacaattg gatcaaaaat aacaaaaaat
     8581 gatggaggtt gtgacagaag tggtcagctc caagatattt cggatcattt tccgtaaaag
     8641 ttacttctgg aacactgttt accaagaggt cgtgagcctg ccgttcagct ccgagtcaca
     8701 aggaacaatt tcaaaaaata gcttctcgtg tttgatgaat attgtaactt gtgattcgga
     8761 attggcagga gaacaccgtt tatt
//
LOCUS       DAZUJR010000101         8590 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.104, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000101 DAZUJR010000000
VERSION     DAZUJR010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8590
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.104"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(48..1514)
                     /locus_tag="ACG804_002507"
     CDS             complement(48..1514)
                     /locus_tag="ACG804_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HFS4833391.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
     gene            1902..2498
                     /locus_tag="ACG804_002508"
     CDS             1902..2498
                     /locus_tag="ACG804_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFS4833392.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAEEKEYMNDADRFRVFG"
     gene            complement(2556..3038)
                     /locus_tag="ACG804_002509"
     CDS             complement(2556..3038)
                     /locus_tag="ACG804_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833393.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(3144..3341)
                     /locus_tag="ACG804_002510"
     CDS             complement(3144..3341)
                     /locus_tag="ACG804_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833394.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            3636..4394
                     /locus_tag="ACG804_002511"
     CDS             3636..4394
                     /locus_tag="ACG804_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HFS4833395.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            4454..4882
                     /locus_tag="ACG804_002512"
     CDS             4454..4882
                     /locus_tag="ACG804_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833396.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            4928..5000
                     /locus_tag="ACG804_002513"
     tRNA            4928..5000
                     /locus_tag="ACG804_002513"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4961..4963,aa:Gln,seq:ctg)
     gene            complement(5150..5521)
                     /locus_tag="ACG804_002514"
     CDS             complement(5150..5521)
                     /locus_tag="ACG804_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFS4833397.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            5736..5921
                     /locus_tag="ACG804_002515"
     CDS             5736..5921
                     /locus_tag="ACG804_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833398.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(6004..6192)
                     /locus_tag="ACG804_002516"
     CDS             complement(6004..6192)
                     /locus_tag="ACG804_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833399.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(6216..6479)
                     /locus_tag="ACG804_002517"
     CDS             complement(6216..6479)
                     /locus_tag="ACG804_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833400.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            6637..6894
                     /locus_tag="ACG804_002518"
     CDS             6637..6894
                     /locus_tag="ACG804_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HFS4833401.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            complement(6965..7156)
                     /locus_tag="ACG804_002519"
     CDS             complement(6965..7156)
                     /locus_tag="ACG804_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833402.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(7297..7617)
                     /locus_tag="ACG804_002520"
     CDS             complement(7297..7617)
                     /locus_tag="ACG804_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833403.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            complement(7640..8074)
                     /locus_tag="ACG804_002521"
     CDS             complement(7640..8074)
                     /locus_tag="ACG804_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFS4833404.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            8409..>8590
                     /locus_tag="ACG804_002522"
     CDS             8409..>8590
                     /locus_tag="ACG804_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFS4833405.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
BASE COUNT         2722 a         1695 c         1361 g         2812 t
ORIGIN      
        1 aacaggaact gctgcaaata agcaattcct gtttttatgt tcattgatta atgaatagag
       61 cccattagtt ttttgattgg ttctttcaca gtaaatagca agataccacc gacgattgct
      121 actgcaccga taataccgaa gtaagcagat tctgttcccg gtgtgtagaa gcgtgcaatt
      181 tgtgcattga ttgcttgtga agaagcatca gctaagaacc aaatagcgat tgtttgtgat
      241 tcaaatgctc gtggtgctaa ttttgttgtc acagacaaac caactggtga aagacacaat
      301 tcagcaataa ccacgatgaa gaaacttccc aacaaccaca atggacttac ttttccactt
      361 gtaccataaa gcatacccgg caacatcaat agcaagtacg ataatcctgc aaataaaagt
      421 ccaagagaga atttcactac tgtagatggt tgacgttcac caagtttcgt ccacatcgtt
      481 acgaatactg gtgtcagaat aaagatgaaa attggattca atgattgata ccagcttgct
      541 tggatcgtta caccaaatag cgtagattgt gtacgttcac tagcaaataa agctaagata
      601 gatgaacctt gttcttgtaa tgaccagaaa atgattgctg caaggaataa tgggatataa
      661 gcccatactc ttggtttttc ttcagcagtt acatcttttg aagtcagcat tttgataaag
      721 taatacaacg gtaagataat ccccaataca ctgattgtat tgacaaaaaa gtcaattgtc
      781 agatgaccag ttagttgtgc cccgccgaat actgcagcga taacaacaag tgcgatgatc
      841 aagttacgga tgaatccttt acgttcttca gttgtcaaag gattcggcgg tgttgtaccc
      901 actccgtcta atgtcttgcg tccttggatg atgtattgta ataatccaaa gaacatccca
      961 atagcagcta aagagaaccc taaatgatag ttatattctt gaccgattgt accaacgatt
     1021 agtggtgcta ataatgcccc taagttgaca cccatgtaaa aaatcgaaaa tcctgcatct
     1081 cttcgcaagt cagtctttga ataaagatgt ccgaccatgc cagaaacatt tggtttcaaa
     1141 aaggcggttc cgataataat caatgccatc gaaacaaaca atgtacttac accaaatggt
     1201 aaagccaaga cgatgtggcc aagcataatg aaaactccac cgaagaatac agtgcgtttt
     1261 gctcctaaca ctcggtcaga tacccatccg ccgacgatac tagacatgta gatcaaagat
     1321 ccgtagatcg acatgatagc taatgctgtt gctcgtggta atccaagtcc cccgttggca
     1381 actgtatcgt acatataata gataagtaat gcacgcatac cgtaataact aaatcgttcc
     1441 cacatctcag tgaagaacaa agttgacaat cccttcggct gcccgaagaa gcccttgtct
     1501 tgctgttttt ccataatcta taccccaatt ctttaaattt tcagaaaata ttatacatct
     1561 ttaccgaaaa atttaactaa aaaacttatt taagaaatat aaactaattt tctataaaag
     1621 caagtaattt ttaatggcaa tatcataaaa aaaaagaaga tagagattta ataattatat
     1681 atcagctgtt tttttcaaat aagcaaaaat tcctaaaaca caacaatgaa agcgataact
     1741 aagaaaatcc ttacataacg atttttctta ttaaaattgt tttttgaact tcgcttattt
     1801 tttgtgagca tatctgttta cttacttttt gtaaggtgct atacttcatt tcgtaatcaa
     1861 ttaaaaaaat gcaaaacgca aatcaaagga gaaattttat tatgacaact tttactgaca
     1921 ctttgaaaaa ccgccgttca atctatcatc taggacgtaa tgtttcactt tctaatgaag
     1981 aattaacaac tttgatcaaa gaagcaatta aagaaagccc aactgctttc aatgctcaat
     2041 caacacgcgc agttatcctt ttcggagatg cacatgaaaa actttgggaa atcactgaag
     2101 aagcacttcg cccattgact ccagcagaag ctttcccaaa tacacaaaac aaattagctg
     2161 gtttcaaaaa tggttatggt acagtattat tcttcaaaga tactgacgtg gtaaaaggtc
     2221 tacaagaaca atttgaatta tatgcagaca acttcccaga ttggtcagaa caatcaaacg
     2281 gaatcgcaac agctaatact tgggtagcat tagttgataa aggattgggc gcaaacttgc
     2341 aacattacaa cccagttatt gacgaagcag ttgcaaaaga atggaatatc ccttcaaact
     2401 ggaaactacg ttcgcaatta gtattcggtt caccagaaac accggctgag gaaaaagaat
     2461 acatgaacga tgccgatcgc ttccgcgtat ttggataatt ttatttgaaa taaaaaacag
     2521 aggttgtgac aaacatcttg tcgcaacctc tgtttttatt ctggatcaat cataatatca
     2581 atctctgcct catcgtttaa gcgttgggac aaaaatggaa ctaattcttc taatgatgca
     2641 gaaaatttca gcatcggtcc tcgccatccg tttcggaaaa aattcatttt tacgatttta
     2701 gaaccttttg gctgatataa tacaatttta ttgatctcag aaaaaggaac accttttttg
     2761 tcaaagctat tcaaaacaag tccttcttct gtgattcctc tactgtccaa caaaaaacta
     2821 ataaaaatca ttgctgacaa gatccctttt gccaattcat ctgctgtagg atgactgatg
     2881 agtgtatacc aaatgactag tgacactaag aagggtatca ccaagtagac ccatcgattt
     2941 cgcacagtcc gataaataat ttcttttcga accagccaaa gaaataaaaa catcacaaca
     3001 acgaataaaa acaatagaac cgtaaagaat gttaccatga caactcgcct cgctttttct
     3061 tctccagaaa ataggaaaag aatactgatt taccttctca aagaaattgg acttgcagca
     3121 cgccgcacgt ccaattgttt tctttattca aatgtatcat attttgcaac aaccatgctt
     3181 gctttttcat ctaataattc ttggtcctct gcagcacatt gggcaacttt gaccacggcg
     3241 cagtttgtca tttttgatac aacttcacca atgaccgttt ttgtaaaacc aattggtttg
     3301 catgcatatt gttctcctaa attaatcatt tcttccgtca tcaaaatcct cctaaactgc
     3361 tggaactttt ctccacatta ccactgctat ttctttggag atttaactca ttgattttta
     3421 tttacagtta aaaatcaacc ttacaggcat tatagcgtac tgttttcgtt ttcacaatta
     3481 aaacagctgt tgtatttaga agaatttttt tcaaaaaatt aaaacatatt ccttaaaaac
     3541 taattatttc ctacatatta aaatataata cttccatttc caataaaaat acatttataa
     3601 taggaaagat aaacagctga aaagggagat ttcaaatgaa gaaaaaaacg ttcaaaaaac
     3661 tattgtttct agggggcaca gctgctcttt tattaagcgg tacaagttat tacctacata
     3721 tccattctcc agaacataca atgaacactg cacaaaaaag ttcaacacaa aaaacgaaaa
     3781 agacaaaaga gaaagcagaa gttttactag atgttccatt agagagccag tttgattctc
     3841 cttctttaga aaatggctgt gaagtcactt cgctttctat gcttttatct ttttatggtt
     3901 atgaaacaac taaaaaccag ttagctgagc aattggatta cgtccctgtt ttcaatgcag
     3961 atgggactca tggcgatcct aatgaaggat ttgttggtga tatcagtggc ggagactggg
     4021 ctatggtcgt ctatgttccc ccagttgcct cccttgctca gcaaatcgtc caaacggatt
     4081 atcacacttt tccaaaaacc gatgctcaac tcgatgatat caaaaaagca ctatctaaag
     4141 gaaatcctgt ctggacttct gtgactatca attttgaagt cccagatgaa actgatttta
     4201 tgacttggac cacaaataat ggagaagtaa gagtcactcc tcttgttcat gcttgtgtag
     4261 tcactggata tgacaaagaa aatatttatg tcaacgatcc ctatggtgta aaaaatcgag
     4321 cagtaccgat caacgatttt tcggcgattt tcactgcaat gggtggacag atgctaactt
     4381 tggagaaaag ctagtaattc aaacaaaaat cccttatact caagatacca aacctttgaa
     4441 gggagcgtag ataatggaaa aattcacaca taaaaaaatg gatccaaatg aaattccgat
     4501 tatttttgtc cgtgactgca agggaaatgt tcaaggtaaa gtctctatta atgagtggaa
     4561 cgagcgtcgc agacctgcta ccctcaatga actggaaatc aaattgtatc gtcaatctct
     4621 tgtttattac gcagatcaag agtacgagaa agccaccgat ttattgaaat ttctaattgc
     4681 tcgaacagag tatactcgct ttgaatatat tgaacgttta gcaaacatct atcatattat
     4741 gaatgaacct gtcaaagaat atcagttatt ggacaccgtc ttgtcagtag cagaactgat
     4801 tgcccttcct gctggattag aaaagaaact agtacgccgc cttttacgag taaagcaaca
     4861 actatccgat caagaaaaat aacttgcgtt tttttaggaa agtgctatga ttattttgtt
     4921 gaataaatgg gatgtagcca aactggtaag gcacttgact ctgaatcaag caattgtagg
     4981 ttcgaaccct gccatcccaa tttgatgtgc ttgctgaaaa aatgaacccc ctgtaaaaga
     5041 acaatctttt tgcaggggga ttattgtatt atttttacta cttgtattta gtttacataa
     5101 ttaaattatg aataataaaa tcgggcgtat tcttaataca aaaactgatt tacccaataa
     5161 ttgctaatgc tttctccgga actttttctc taggaacttc ctcatacgtt tctatgtgtg
     5221 ctcctttatt gctaattttc aaataatgat tttcttttaa cacagaaaga ccattaaatt
     5281 caaccgttcg ttctttccca ttggcatcag cagctttctg cacatacctt gctgtaccat
     5341 attcatttac ttcctctggt ttttgtgtct ttacatagac ctctcctttt tcaactaatg
     5401 gatttagctg atcaagtata ccagggattt ctccataact tccttcagta taatatttca
     5461 gtccaaatag caaaatacca ctaatcgccg ccagtccaat caaatattta atcactttca
     5521 tctttctacc tccttgttat atattcagta tatgggtcag ttaaagaaat tccatccgtc
     5581 ccaagttgga gatttttctc ctactttaga agcgagaatc gagtgttttt ttagtaaaaa
     5641 tgatcgttat ttgatattat tgacgtgtgg ataaatcagt ttttctcgtt ttgtccatgt
     5701 aaaaaatcat gttgatagca aaggatgtgt tcaaaatgaa tcaagaagaa ttatttcaaa
     5761 aagtcaagga aatgattaag aacggcaatt tcgatggcgc aaaacgattt atcgaagaac
     5821 ataaagaaca attaggacct tataaagaga aagcccaaaa tcttttaaaa gatgtaaata
     5881 tcgacagtgt caaaaacaaa tttaaaaatc tattcaaata agtaaaactt tcacttttgt
     5941 aaaatcaaag gaggacaatg ctgctgcatc gtcctccttt ggttcttttc tgaatacttc
     6001 atactaaaat aaacgtgtcg gatcgtaatg ataagtcaca ttgccgttca gtgaggcttt
     6061 tcccaccaca tatttacgat tctccaactt cagccacgct tctcgaaaag ccattaattc
     6121 ttctcttttt acatcaatct tttcgatttt tccatcgatc aaatcttgaa taagttgttc
     6181 atatggattc atttttttcc tccatctgct gtcaatcaat aagttgtaaa aataggttca
     6241 tatgcttttt tggtatctag atcttctctg actttgactg tcgtataaat aattttttct
     6301 actgggatac tataataact tccttcacca ttattgaatc ggtgaacgtc tttctttgct
     6361 aaaataccat ttattttatt cgtcagtaca cgttgttcga cactgttact tacaacatag
     6421 taaatcaccc gaatattatt gatcaaatgc aaatcgattt ctaacactac atgatccatg
     6481 aaaatcccac tccttctttc actttgatta tagcaagttt ctcctctaat ttcaaaatcg
     6541 atacagattt taccggataa atccacaaaa ctgcttgcgc catttcgcac aaagtgttat
     6601 tttgtatcat ggactttatt tatcggaggc aatagtatga tcgcgatcgg tcaatttgtt
     6661 ttttatattc ctttttttat tatgataagc attcttttct attacataaa atggacaaaa
     6721 aagaagtttt cagttttact ggcctcttta cctgctgtat attttactta tcaaattttt
     6781 tcttttaggc attgggaaac aacgtctgta ttaataacac acatcatcga attgacgctt
     6841 tcagtaattt ttcttattat ttggatctat tttttatata agaatcagaa ttgaatccct
     6901 cgcatgttta aaaagaaaac gattaaagat gcagcaaatt tctgccgatc tttaatcgtt
     6961 ttttctattc tgttatacca aaaaaatgtt tgaatcggtg aaggatcgtt ccttgtttta
     7021 attctataaa ttcttgtgcg atcgggtact tttcttccaa attttctttg ttcttttcga
     7081 tcaggctttt cgcttcttca tattttttat ctgcacatag tgcttttact tcctgtaata
     7141 cttttcctgc ttccatttgc ctcaccctct tgccatttta ttgctttaag ttttatttaa
     7201 gttatacgca ttattctagt ttcatcccaa ataacctttt ttcattttta ctcctcgaac
     7261 taatcagttt tctaaaggct gattggttcg tcttttttat ttttcctcca tttcattctg
     7321 ctcttctgtt aatttatcta atgctttgat tgatgctgcg gctcttgcat aatcatagct
     7381 gtataattcc ataaatttat caggcagaac aaaccacgct ggatgataac cgttagctgt
     7441 gacagggaat cctttatctt gttggttatc tccatcccat ctcagagcaa cacctttttt
     7501 tcctttccac tttactaaag cgatcgagta tcccttcttt gtttgtgtgc cgtcttcaat
     7561 aattgctaaa atttctattt tttcttttgg cgcacggact tcttgaggac gaaccatttt
     7621 ctattcctcc cttatctcat tacttcacga ccaacacact gcaaggggca tgtgatacga
     7681 cataagaagc ggtcgatcca actaatgctt gttgtatagc accttttcct gtcgctccca
     7741 taacgatcaa atcaatattt tcttgtccag ggatgacatt ggcaatcaaa tttcttggat
     7801 ctccagtttc aactattgcg tggatctcag caatgccgta ctctttggca tcattgattt
     7861 ttttcagcat ggctacttct gttctttgtt tttcatctgc atagattttt gaaaaggcat
     7921 aggcactatg ggtcagctca actttgttga tgattgacac gataaataag tgggcttcat
     7981 tgtcctttgc taagtcaagg gcttcagcga acgctttgat cgattgtctt gatccgtcaa
     8041 ctgctaccat gatgttctgg tatcttttac tcattggaac cgcctccttt ttcttttatt
     8101 gtaacatctc aagcaaaaat acaaaaaata tacgcaatat gtaaataaaa tgatgaacaa
     8161 aagcaatttc tttcaagtta tttatacatt tcttttctca tcagaacacc tgttctaatc
     8221 ccattatttc tgcattatgt gaaattcctc atcatttttc acatcgagcg aacatcattc
     8281 tgttacaaaa aacgtggatt tgtcataaat tgtcatgctt cttttaccta tgaaatattt
     8341 tcacgtgtta aagtattcct cgttgaacac aacaaataaa actttttaac gaataaagga
     8401 gatttttcat gacatcactt aaaactttac tttttggaac aactttggct gccggcgctg
     8461 cattcttcat gggaacgact gctcatgcgg acgaagctta taccgttcaa tcaggtgata
     8521 ctctatcaac gatttctcaa aaatacgttg gtgataactc cttgatcaat gccattgcag
     8581 aatcaaattc
//
LOCUS       DAZUJR010000102         8493 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.105, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000102 DAZUJR010000000
VERSION     DAZUJR010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8493
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.105"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..149)
                     /locus_tag="ACG804_002523"
     CDS             complement(<1..149)
                     /locus_tag="ACG804_002523"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF025054.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4833406.1"
                     /translation="MENHVLETGMQKITTHASITAKPFFEKRGYKVINEQTVELRGQL
                     FTNFL"
     gene            complement(593..1714)
                     /locus_tag="ACG804_002524"
     CDS             complement(593..1714)
                     /locus_tag="ACG804_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HFS4833407.1"
                     /translation="MDKYNVKTSFQKWFSAINFSGLSENSQSLISDFDFYSKKLDFQT
                     TLKVLLHAVYEELPSYREIDRAFLDQRLCKELGIDSLCYSSLSRRAPEIKQEVLMEIF
                     TQLVARISAQQPSSKTTSLQLIDSTTIPLNKAWFPWAKFRKTKSGIKLHLNLCYLDKT
                     NQYPESFTMTNASEHDRNHLEVLVDKTQATYVVDRGYFDYKLLDKLNRDGYFFVTRTK
                     SNTKITILDQIEVADTTTRDGTIISDQQVILVGGVNHVTERFRLVTVLTKGQKILRMV
                     TNLFDVSPNEVADMYQARWQIELLFKHLKQNLTIKRLYSHSEQGAINQVILTLIATLL
                     TYVIKIELNTTATLFQLKRTFHYLMFEPAEEWFKRYRPG"
     gene            2042..3451
                     /gene="istA"
                     /locus_tag="ACG804_002525"
     CDS             2042..3451
                     /gene="istA"
                     /locus_tag="ACG804_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HFS4833408.1"
                     /translation="MDDIKTIKHLRNNRDQSIDQIRKAMNINWRTAKKYADSDQLFIT
                     DPTRKNKSMMDDGWGEIIGSWLEEDLRLRRKLRRTAKAIHEQLKPLGFPGSYRTVCVY
                     ISQWKKQRYDETNYQAVDRLDHPIGEAQVDFGTMEVMHEDHMKDIQLLIMSFPYSNAT
                     SASAMPAQNQECFLEALKQLFNQCGGVPKTIRIDNLTPAVKKTKSKFEEAQLTDEFLR
                     FTIHYGCDVQVCNPRSGHEKGHVENKVGYVRYNFFSTSPIMDSFESLNKQLEEQLKAD
                     RKRTHYSKHQLIEDLWKKENKALHSLPQEDYPIFKEVEAKLNRYHEMKLDQTVIHIPK
                     AYGYSQLTVVLTWNKFKVLTPHGEILMNEYRPYMNKKRLIPWSDIMKQWSNKLNVVSY
                     SRYWKYLPARLQNYLAIDNNHLKYRRIKQLLSLLATYDIQQINEQFYELVVQEDAPSD
                     FDVNWSNYDALTKTGGVQK"
     gene            3448..4176
                     /gene="istB"
                     /locus_tag="ACG804_002526"
     CDS             3448..4176
                     /gene="istB"
                     /locus_tag="ACG804_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HFS4833409.1"
                     /translation="MIGQTLEDYCKKLRLSHIITNIPRASFEAPEQFITDLFRLELET
                     RQQIKLERMEKLAKFPVPKSLKNYEWHEDIFLPSHLDKETLVSLDFLKRQENIVCVGS
                     PGTGKTHLAIALGRKACSEGVSTKFFRVNNLVEQLENALKKQQLASFKKRFETTELII
                     LDEMGYLPLTKEGAELLFQLISDWYEQKSIIITSNLEFSQWNRVFMDSRLTAALVDRL
                     IHHAHIISFKGESFRLKNSLSKSY"
     gene            complement(4304..5215)
                     /locus_tag="ACG804_002527"
     CDS             complement(4304..5215)
                     /locus_tag="ACG804_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFS4833410.1"
                     /translation="MKIKIERSNKEKIPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GIYKNFTAIDQHTTHEKVVVKEKIVNTSGVENFTVDFVKEYFSWKNNKEVIEKRMTNL
                     EQYLTEEGLALSQDMVRADIPTSSEVVSVKILDVEKHSEEFVVSFVVDQKITEGKKTQ
                     SISSAYRLMIFEDEKGNHIVTSLPTMIGKPEKAKHKVRQVKSDSKIDSKTTEEITEFL
                     ETFFRLYPAASEKELEHYVEKDAMQPINTNLKFVELVNPIYKQKGKAIQVIVGVEYLD
                     ELSKTTSVFQYRLKLYKNENWTISNCE"
     gene            complement(5232..6239)
                     /locus_tag="ACG804_002528"
     CDS             complement(5232..6239)
                     /locus_tag="ACG804_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HFS4833411.1"
                     /translation="MNLKKLSIISLTFLTISFVGILMCVGLLFGEDGEGSGSSGTSPG
                     GSSVSEVVLKHRSMVEKYAKESDITEYVSILLAIIQVESGGTMEDVMQSSESAGLSPN
                     SLSTEASIKQVCLYFSSLVKCSKELGCDQDSIIQAYNYGDGYLDYVAKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENSGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSIPGTGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLIFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTDSYWQQHIIGAGRYK
                     Q"
     gene            complement(6236..8365)
                     /locus_tag="ACG804_002529"
     CDS             complement(6236..8365)
                     /locus_tag="ACG804_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFS4833412.1"
                     /translation="MKKKLFRIVGIVFISIVTLTVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAKSIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRTVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTKIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEGRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKRAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRTFAFGGGAAVGGKLATSSTKGKGSSKINRVSNRKNHSARSINELNSDLKK
                     QEQPVGTKKESRINLVGRKVGKVLDTKEIVKDKAKQAKNQVTDAPTNLKYSLHKGMEK
                     TKKVPEDFKRGPFEEKANRGELREKQRQRRDAKMDEKRKVLNEAWNRHEKGRENVPIK
                     KEIKPQKNELPENRSLKPRVQVHSNPEIKRKLSSQEVIPNGSTQPLSKNNSFQQVKQR
                     FTFPKRTNQQVQRKKNTRPKPKPGEKR"
     gene            complement(8370..8480)
                     /locus_tag="ACG804_002530"
     CDS             complement(8370..8480)
                     /locus_tag="ACG804_002530"
                     /inference="COORDINATES: protein motif:HMM:NF024254.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833413.1"
                     /translation="MMQDLYGRVGVVQVHPVFEELFHAFDTRPPVQERME"
BASE COUNT         2600 a         1727 c         1486 g         2680 t
ORIGIN      
        1 attaaaaagt tagtaaataa ttgccctcta agttccacgg tctgttcatt aataacttta
       61 tatcctcgtt tttcaaaaaa tggctttgcg gtaatggaag cgtgggtagt gattttttgc
      121 ataccagttt ctaaaacatg gttttccaat tcatctgcaa ttttagtcgc aatacctttt
      181 ccttgatggc tatgtttttg tcacaacttc agtattcctg taacaatacg gatttcagta
      241 tacaacaaca gcttttgaaa agatacttgc aaaaggatta agatatctat gacctgctat
      301 gctcactgat gttgaaaaga atgttttatt aggattgagg taagcaagat agtgaatatg
      361 tccggaaagc ctgtaaaata aggcttttcg gacatatgtg aagttataaa aagatagcga
      421 aaaatctatt tagtatcact aatgttgcga acatatcgtc agaatagtct gacatttatt
      481 tcttgctaaa aatttcaaaa aagtcaagtg ctgacgcagc ggatgactat tttccagaaa
      541 attttagtat gtattcaaaa atcaaacgtg acaacagcta ttaactacat cctcatccag
      601 gtctgtaacg tttgaaccac tcttctgcgg gctcaaacat taagtaatgg aaggtacgtt
      661 tcaattgaaa cagcgtcgct gtcgtattca actcaatttt tatcacataa gtgagaagcg
      721 ttgcgattaa ggtgaggatg acttgattta tcgccccttg ttcactatgt gaatatagtc
      781 gtttaatggt cagattttgt tttaagtgtt tgaacaacaa ttcaatctgc caacgggctt
      841 gatacatgtc ggccacttcg tttggcgata catcaaagag attggtcacc attcgcagga
      901 ttttttgtcc cttggtaaga accgttacca acctaaaacg ctctgtcaca tggttgacac
      961 cgccgacaag aatcacttgt tggtcactga ttatcgtccc atcacgggtt gttgtatctg
     1021 ctacttcaat ttgatccaag atggtaattt ttgtattaga ttttgtccgt gtaacgaaga
     1081 aatagccgtc acgatttagt ttgtctaaca acttgtaatc aaagtagccg cgatccacca
     1141 catacgttgc ttgcgtttta tcaacaagaa cttcaaggtg attacggtca tgctcactcg
     1201 catttgtcat cgtaaaactt tcaggatact gattggtttt atcaagataa cagagattca
     1261 aatgtagctt gatgccagac tttgttttcc gaaacttggc ccatggaaac catgctttgt
     1321 tcaacggaat agtcgttgaa tcaatcaatt gtagactggt tgtttttgag cttggctgct
     1381 gagcagaaat tctggcgact aattgcgtaa aaatttccat caatacttct tgcttgattt
     1441 ctggcgctct acgagataac gagctgtaac acagggaatc aatgccaagt tccttgcaga
     1501 ggcgctgatc taaaaaggcg cgatcaatct cgcgatagct tggcaattct tcataaaccg
     1561 catgaagtaa cactttaagc gtcgtttgga agtctagttt tttactgtag aaatcaaagt
     1621 cgctaattaa gctttgagag ttttctgata aaccagaaaa atttattgca gaaaaccatt
     1681 tttgaaatga ggtttttacg ttatacttat ccatgcgtga gtccttttta ttggtcttgg
     1741 ataagtcatc cgagaatagt ataaaggact tttttgcgtt tggatagctt tgtattaggc
     1801 ttttgatggg ttaaaaagtc tttgcaacac tagtaattta gtatttatgt ataaattgaa
     1861 agatatttta ccaccactta gtcttcttaa aagtgatcca acattttgtt tgtggcagaa
     1921 tttaactaca cactaatgca gccgaaagta cacaactatg cagcagtttg actgcgaact
     1981 ggtttccttc catcataagt ttgaatgact tagtgatgga ggtacagaaa ggttgttaac
     2041 tttggatgat attaaaacaa taaaacattt gagaaataat cgtgatcagt caattgatca
     2101 gataagaaaa gcaatgaata tcaattggcg aacagcgaaa aaatacgccg atagtgatca
     2161 actattcatt acagatccca ctcgaaaaaa caaatccatg atggatgatg gttggggaga
     2221 aatcatcggt agttggctag aagaagacct acgtttacgc agaaaacttc gtagaacggc
     2281 caaagctatc catgaacaat tgaaaccttt gggtttccct ggctcctatc gaacagtttg
     2341 tgtatacatt tctcaatgga aaaagcagcg ttacgacgaa acgaattacc aagctgtcga
     2401 tcgtcttgat catccgatcg gagaagcaca ggtcgatttt ggaacaatgg aagttatgca
     2461 tgaagatcac atgaaagata tacaacttct tatcatgtca tttccctata gtaatgcgac
     2521 gtccgcaagt gccatgccag ctcaaaacca agagtgtttc ctggaagcat taaaacaact
     2581 atttaatcaa tgcggcggcg ttccaaaaac gatcagaata gataacttaa ctccagcggt
     2641 gaaaaaaaca aaatcaaaat ttgaagaagc acaactaacc gatgaattct tacgtttcac
     2701 cattcattat ggttgtgatg ttcaagtctg taacccacgt agtgggcatg aaaaaggaca
     2761 tgtcgaaaat aaagtgggtt atgtccgata caatttcttc tcgacttcgc caatcatgga
     2821 ctcttttgag tccctaaata agcaacttga agaacaatta aaagcagatc gaaaaaggac
     2881 gcattattca aaacatcaat taatcgaaga tttgtggaag aaagaaaata aagcgttaca
     2941 ttctcttcca caagaggatt acccaatttt taaagaagtg gaagctaaac taaatcgtta
     3001 tcacgaaatg aaattggatc aaacggttat tcatattcct aaagcatatg gctattctca
     3061 attgactgtt gttttgactt ggaataaatt caaagttctt acgcctcatg gagaaatatt
     3121 aatgaacgaa tatcgcccct atatgaacaa aaaaagattg atcccatgga gtgacatcat
     3181 gaaacaatgg agtaataaat tgaatgtcgt tagttattcg aggtattgga agtacttgcc
     3241 tgcacgcctt caaaattatc tagcgattga taataatcac ctgaaataca gacggataaa
     3301 acaattacta agtttattag cgacctacga tatccaacaa attaatgaac aattttacga
     3361 attagtcgtt caagaagacg ccccctctga ctttgatgtg aattggtcaa actatgatgc
     3421 attaacaaaa acaggaggtg tgcaaaaatg attggacaga cgttagaaga ttattgtaaa
     3481 aagcttcgat taagccatat catcacgaac ataccaagag cttctttcga agctccagaa
     3541 caatttatta ccgatttatt ccgtttagaa ctggagacca gacagcagat caaattagaa
     3601 cggatggaaa aattagccaa atttcctgta ccaaaatcgc taaagaacta tgaatggcac
     3661 gaagatattt ttctaccatc tcatctagat aaggagaccc ttgtctctct tgattttcta
     3721 aaaaggcaag aaaacattgt ttgtgttggc tctcctggta cagggaaaac acatctagcg
     3781 atcgcattag ggagaaaagc ctgtagtgaa ggtgtttcaa ccaaattttt ccgagttaac
     3841 aatctcgtag agcaattaga gaatgcatta aaaaaacaac agctagccag tttcaagaag
     3901 cgattcgaaa caacagaatt aattattctt gatgaaatgg ggtacttacc attgacaaaa
     3961 gaaggagctg aacttctctt ccaactgatt tcagattggt atgagcaaaa gagcattatt
     4021 attacctcta atttagaatt cagtcaatgg aatcgagtgt ttatggattc tcgattaaca
     4081 gctgctctcg ttgatcggct aatccatcac gctcacatta tcagcttcaa aggcgaaagt
     4141 ttcagattga aaaattcatt atctaaatca tattgaagga aaaaactagt tgcagcaaaa
     4201 ctctgcactt tcggctgcat ttttttgtaa aaagctattg cacaacacaa acatttgaac
     4261 gacgtaattc caaatgttgg attgctttta gataatcttt tatttattca caattgctaa
     4321 tagtccaatt ttcatttttg tatagtttta atctatactg aaaaacactt gttgttttgg
     4381 acaactcatc aagatactca acaccaacaa tcacttgaat cgctttaccc ttttgtttgt
     4441 aaataggatt cactaattcc acaaatttca aattagtatt aattggttgc atcgcgtctt
     4501 tttcaacata atgctctagt tctttttctg aggctgctgg ataaagcctg aaaaacgtct
     4561 ctaaaaactc ggtgatttct tccgttgtct ttgaatcaat ttttgaatca ctttttactt
     4621 gtcttacttt atgttttgcc ttttctggct taccaatcat agtgggtaaa ctcgttacaa
     4681 tatgattgcc tttttcatct tcaaagatca tcagacgata tgcagaagaa attgattgtg
     4741 tctttttccc ttctgtaatc ttttgatcta ccacaaatga aacgacaaat tcttccgagt
     4801 gtttttcaac atctagaatt tttactgata caacctcgga actagtggga atatccgctc
     4861 gaaccatatc ttggctcaaa gcgagccctt cttctgtaag gtactgctca agattagtca
     4921 ttctcttttc aattacctcc ttgttattct tccatgaaaa atattctttc acaaaatcta
     4981 cagtaaaatt ttctactcca gaggtattca ctattttctc tttcacgacc actttctcat
     5041 gagttgtatg ctgatcaatg gccgtgaagt ttttgtagat tccaaaagca aggctacaag
     5101 acaataaaag ccaaagggca agcaccattt ttcgatgctt gcccacggat actactcgtt
     5161 ctttcttctt ttttggaatc ttttccttgt tacttcgctc aatttttatc ttcattttcc
     5221 attcctcttt tctattgttt ataccgacca gcaccaataa tgtgctgttg ccaatagcta
     5281 tcggtaagat tggtccaacc caccggatct cctgcatgaa acattctgtt ctctcctgca
     5341 taaatgccca catgagtcac ataagtaccg gcatcataag ttgaatgaaa gaaaatcaaa
     5401 tcgcctggtt tggcatcttt taagtcaata tgagtcatag catcatattg atcctgagcc
     5461 acccgaggga gtttcaaacc aactttggca taacaccatt gagttaaacc actacaatca
     5521 aacccagttc cgggaattga cccaccaaat acataagccg ttccttcata cttgaacgcc
     5581 tcgtcaaaaa ttccttggac tgttttatca tcaaactgtg ttgtagttag gtactgcttc
     5641 actaataagc aataaaacat attgccatag ttataccgcc acccactatt ttccttaatc
     5701 gcgatgggat tgggataatc gactttttga ccacccgatt tttcttttga aaaagattcg
     5761 gctaaagcaa aactatgctt ctttccgttt ttcgcgacat aatccaaata cccgtcacca
     5821 tagttataag cctgaatgat actatcttga tcgcatccta gttctttgga acacttaacc
     5881 aaagacgaaa aatagagaca cacttgtttg atggatgcct cggtacttaa tgaattcggt
     5941 gataaacctg ctgattcaga actttgcatg acatcttcca ttgtacctcc agattcgact
     6001 tgaataatcg ccaaaagaat cgaaacatac tctgttatat ctgattcttt ggcatacttt
     6061 tccaccattg aacggtgttt caaaactact tctgagacac tactacctcc aggagaagtt
     6121 ccagaactac cacttccctc accgtcctca ccaaacaaca aacccacaca catcaagatg
     6181 cccacaaaag agatggtcag gaaggttaac gaaataatac tcaatttttt taagttcatc
     6241 ttttctcacc tggctttggt tttgggcgag tgttcttttt tctttgtact tgttgattgg
     6301 ttcgctttgg aaaagtgaat ctctgtttca cttgttgaaa ggaattgttc ttgcttagtg
     6361 gctgagtgct tccgtttgga atgacttctt gactagaaag tttccgtttg atttcaggat
     6421 tcgaatgtac ttgtaccctt ggttttaaag acctattttc tggtagttca tttttctgtg
     6481 gttttatctc cttttttatc ggaacatttt cccttccttt ctcatgacga ttccatgctt
     6541 cgttcaatac tttgcgtttt tcatccattt ttgcgtctct tcgttgtcgt tgtttttctc
     6601 gcaactcccc tcgatttgct ttttcttcga aaggccctcg cttaaagtcc tctggtactt
     6661 ttttcgtctt ttccatgcct ttatgaaggc tgtatttcaa gttagttggt gcatcggtta
     6721 cttgattttt tgcttgtttc gctttgtcct tcacgatttc ttttgtatcg agtacttttc
     6781 caacttttct accaactaaa tttattcgtg attctttctt cgtgcccact ggttgttctt
     6841 gttttttcag atcagaattt agctcgttaa tgcttctcgc ggaatggttc tttctattgg
     6901 acactctatt gatttttgaa ctacctttcc cttttgtaga actggtagct agtttcccac
     6961 caactgctgc accgccacca aaagcaaaag ttcgacccac atttcgatta agctgtcgca
     7021 attttcgatt catcaacatt tgcggtttcc gcatgactcg ccttcccatt gactgactat
     7081 cattactttg aaggttaaac atgctcataa tgtcacctaa tttgaaatag ataccggcaa
     7141 aggtcacaat ttgtagaaaa gctaccataa agaagggata ggtggccgaa atattgaaaa
     7201 acatcgtgga gatactgaat gcagtcgtaa tgactaaggt aactcccgct cgcatcataa
     7261 tcgtattgaa caaacgaata atcgcccttt tgcccaaact ctcatacgtc ggcaacatcg
     7321 acaataagaa actaatgggc agaaacatcg caaagataat gaaaaggatt tgtgagaaca
     7381 acataatccc tgtcagaaga aacacaaaaa aggaaatccc aatattaaac aacactaaaa
     7441 agaccacggt tcctaaacgg ttcatggtct tggtaatact gagattcgca ttgtcattat
     7501 cttcaatctc tgctttgact gcttcttccc gatccttacc cttattttca tccggactca
     7561 cggataaaat cttattaacc cgaccctcgc caatttcttc tatattggaa tcatcgaatt
     7621 gtaatagtaa ccagggttgt tgaacttgaa tcgaaaataa actgtctcga atcaaatcca
     7681 cactatcttt tccctggctt tctgaattag gtacaacaat cttggttcca aggctaagag
     7741 ccgcttcact aacgtctgag ctaaagtcat tgatttttgt aatataggtg ggcgcatacg
     7801 caatgaaaga acccgagagt agaaaaatca tcacaaaatt aatgacggtt cggactgctt
     7861 tggtagtttc tcgttttaat aatccggtat acgccacata aactcctaga gctaaaatca
     7921 tcaataatag gaacccaaag tagaatcccg aagtctgtaa tccattttca gtgataccgg
     7981 ctaaagtttg gatattcttt ccaatacttt tagccgtatc cgaaatgaaa tccaacttgt
     8041 aagcttcttg aaccacatag cccgtggcgt ttgataaata cagacttact gtccaaataa
     8101 aattggtaat ggcataaaga ccatacatca cgcttttccc taagccatcc ccccaattcc
     8161 aaggtaacca atcccaagaa ctatccacaa agaaatccag ttgataattg ttcagagaat
     8221 atttggaata aaggtttccg gcttcaactg tatcatcaac cagacctgtc gcctcagcta
     8281 ccgtaccgac taaactcaat agaactgtca gagtgacgat gctaataaaa acgattccca
     8341 caatccgaaa aagtttcttt ttcatcccct cactccattc tctcttgaac cggcggacga
     8401 gtgtcaaaag catggaagag ttcttcaaag actggatgaa cttgaaccac acctactcgc
     8461 ccatacaagt cttgcatcaa gcattgaccg ttt
//
LOCUS       DAZUJR010000103         8425 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.106, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000103 DAZUJR010000000
VERSION     DAZUJR010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8425
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.106"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..505)
                     /locus_tag="ACG804_002531"
     CDS             complement(<1..505)
                     /locus_tag="ACG804_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833414.1"
                     /translation="MISIIWFLFFFIFFSYLKVIKIDSFLVYHTSAMKNLTQNLLKKD
                     NSSILKIELKKENNKSMKISKKAFLLVVLILLSTLYSVNFMRNAQEIYTTGDLSFHLS
                     RIKGLSSIFEGPINYTTFNNYGDGLNYFYPFLTIIPAVVFYGISNNLILSYVLYIWLL
                     NICTILIS"
     gene            471..2108
                     /locus_tag="ACG804_002532"
     CDS             471..2108
                     /locus_tag="ACG804_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833415.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSMGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(2253..2993)
                     /gene="truA"
                     /locus_tag="ACG804_002533"
     CDS             complement(2253..2993)
                     /gene="truA"
                     /locus_tag="ACG804_002533"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HFS4833416.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(3184..3819)
                     /locus_tag="ACG804_002534"
     CDS             complement(3184..3819)
                     /locus_tag="ACG804_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HFS4833417.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(3966..5186)
                     /gene="sstT"
                     /locus_tag="ACG804_002535"
     CDS             complement(3966..5186)
                     /gene="sstT"
                     /locus_tag="ACG804_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HFS4833418.1"
                     /translation="MSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSCLKAIAPI
                     LVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPITLQETVSE
                     KAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSESTKELVDQI
                     SIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLFVALVVYP
                     FLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKESYSISIP
                     LGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGVAGGSLLL
                     IPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELGARKRSGE
                     KIKLKDCLDGLSER"
     gene            5754..>8425
                     /locus_tag="ACG804_002536"
     CDS             5754..>8425
                     /locus_tag="ACG804_002536"
                     /inference="COORDINATES: protein motif:HMM:NF013080.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFS4833419.1"
                     /translation="MNIRDYWLILTPISQNYFTYAVSCTLLFCSIPYTVGFLNKLSKT
                     TIKYLLLFLTIGLVGCSTLFNKDPFALQNGQSILWIFYLFLMGYGLKEWNWKEKVRYK
                     LPQVFISLIVLFGLIILMTQISLIIRGNTDTALRFSKPYSLFAMYYTFSSFLFLEMLS
                     DKLGIKGRGNFLAVFLIVTQVICNFPLVSYRVSTFMKREFPNSGKAWLINIGQFFICY
                     LLAVSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLFVHKSYFLVAAF
                     FYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFFFLLLLISNRFW
                     YALTATLIINLLLTISTVIKMEMREEPVFPSDLKILTGLSELLSMVSPVLLIVGGLIL
                     LLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHKNSPSFLLFNLF
                     KVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMKKYNTKADEINQ
                     TRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTGGLMLSVGYGGG
                     TANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIAIHPFTAALYRR
                     KQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQSNTETSQFIQL
                     STMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAVKKFIQEIDKID
                     KPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAATLNKEVVAPNNF
                     GAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVFVTEDSQIIQEK
                     NLTEKQKEILEDYRLIQYDLVAGNQYSATWATQK"
BASE COUNT         2785 a         1547 c         1293 g         2800 t
ORIGIN      
        1 aactaatcag aatcgtacaa atatttaata accaaatata tagaacataa cttaatatta
       61 agttatttga aattccataa aaaacgactg caggaattat tgtaagaaaa ggataaaaat
      121 agttcagtcc atctccataa ttgttaaatg ttgtatagtt gattggccct tcaaaaatag
      181 aagataaccc tttgattcgt gaaagatgaa aagataaatc acctgttgta taaatttctt
      241 gagcatttct cataaaattt actgaatata aagtactaag taagataaga actactaaaa
      301 gaaatgcttt tttacttatt ttcatagatt tgttgttctc cttttttaat tctattttca
      361 gtatactaga attgtctttt tttaataagt tttgcgttaa atttttcata gcactagtat
      421 gatatactag aaaagaatca atttttatta cttttaaata ggagaaaaaa atgaaaaaaa
      481 acaaaaacca aataatagat atcattttta tgttatttct aagttttgct tacgtcatcc
      541 ctctattcat gtctatggga atctatcata gtgtcaatca ggatacttac tttcatttat
      601 ctcgaatcat aggactagat aatgtatgga gttctccagt aaacttcaat aacttcgatc
      661 atcatggaac aatgatgaat attttttatc catggcttac tctttatcca gcttttttat
      721 tttataaaat gatgggaaat cttgttttaa gttataatat ctactatttt tttatcactt
      781 ttttaacaat ggtcgtttct tatttttcta tgaaacaaat aaaaaacaat cgttatattt
      841 cgctgttatt ttcgattatt tatacatttt ccgcctatcg tgccattgac atattccatc
      901 gtgcttcatt gggagaagct gtcgctttaa catttttgcc tttgatacta atggggtgtt
      961 acgaaattta tattagagat taccaaaaat ggtactggtt gtctattggc atgacgctag
     1021 tagtgtatac tcatttactt tctgtcgcta tggtttctgt atttattgga ggaacgttgt
     1081 ttctttcttt ttatttttgg gaccaaaaaa tcgctagact cttaagtctt ttaaaagcta
     1141 ccgtcctcac ctttttttta agtgcgggat tcttaattcc ttttattcaa caatctagag
     1201 cacaagaatt gaaagtccca ctgggaaaag aattaagtgg tatggctcct agtgatatgc
     1261 tgacacacat tttaaataat aactataaca actatactat tggattattc ttatttctcg
     1321 gattgattgg tgcttttatt tttataaaaa aattaactgc tgatgattta tttattttct
     1381 ttcttggtgt atttgttctt ttttgttcaa ccaatttatt tccttggcaa ctttttaacc
     1441 atacaccagt taagagtcta caatttgtct ggcggttaaa tggtttttct tctttattta
     1501 tagcctatac gatgagtata gtgatctatt atattttttc tactaaaaat aattcatgga
     1561 aaataatggt ctttacgttt cttgcactaa tattgcatct ctcaggagta agcaattcta
     1621 tccatgctaa caaagattca ttaacactta tagcacctga agacgctgtt gctatagctg
     1681 aaaattacaa tcatactgat tatgcaaaca aagagtcaat ctatcatcct gatatgatta
     1741 ataatgatca atatttacta ggtaaccagg aaataaatcc aacaactcat tttatgagta
     1801 acaaacttac aattgaatta gataattcga ataataaaaa tactgtcttg acgacaccta
     1861 tttatcgtta taaagggcaa gtggcttcta ttaatggcaa actagtacaa acaaaattat
     1921 ctaagtttgg cacaactgaa ttaactattc ctccaggtat aaataaagtc gttattactt
     1981 atcagtacac aaaactagca attgcttcaa gatatttatc tatcgttact ttgattttat
     2041 ttttacttta tcgatttact ttttctaaac aaaaacaacc gagaagagaa gtacaacatt
     2101 ctcactagat ttttatttaa gaaagacttt ttagctgtac acataaacag gctaaaaagt
     2161 ctttttttat atttctttaa tttgcttcat acattattta acatcgatat ttatactgtg
     2221 aaacatgcgt ttcatccatt atcaaagtat ttttatcgat aataaacttc atccaaaaac
     2281 agaccttgtg cagggacggt ttctcctgca tgttgccgca ctttgctttc aaatatttca
     2341 tcgattgttt ctatcggcat ggcacctgtg ccgatttcta gtaatgtccc catgataatc
     2401 cgcaccattt tatataagaa tccgtctccg acaaaagtaa aatgaagcat ttctcccttt
     2461 cgttcgatag ataattcatc aatcgtacgc actgtggatt tttttgattt tttcaatgca
     2521 gaaaaaccaa tgaaatcatg tgtacccact aatttttcgc aagctgcatt cagcttgtcc
     2581 atatccaact cttgagggaa ataaaagctg tggtttcgct caaatgctga aggaatcacg
     2641 ttgttccaaa cataatagct gtattttttg cccaccgcat tatatcttga atggaagcgc
     2701 tcaggcattt cttcgattct tttgatgaca atatcccgcg gaaggtaacg attcataaag
     2761 tcgatcattt ctgccagtcc aatttctgtg tttgttttaa aatttgctac ttgtcctcgc
     2821 gcatgggtgc cagcatctgt tcttcctgat ccaataattt ctatctcttc atttgtcatc
     2881 tgatgcaata ctttttcgat ttttccttga atggttttat cgtcatctcc aagtctttgc
     2941 catcctgaat atctttttcc gtcatattcg attgtcaact tgatgtttct catattttag
     3001 tggctcctct gtcttccatt tggtcttctc tctacctttt taagattgta gcacaaaata
     3061 tagctccttt cttctctaaa acagaagcta tacaagaaaa ctgtggaaat atatatttca
     3121 gaaaaacaaa aaacagccac cggatgaagt atccgctgac tgttcaattt gacggctcaa
     3181 gttttactgt ttgagatgca agatactcaa ccaggcaatg ggcacataat taaagaaaaa
     3241 actgattctt tggcaaaaac ctattttatt cagtaatggc caagaattta tagaaggaat
     3301 tcttgccagt ccataaatcg ccgcaaaaag caaactgatc acagacagtc caaggtataa
     3361 gtggcttacg tccatttgcc cattttttcg atagatcaag aaaagaagaa ctggaaacaa
     3421 taaaaaacca ctgtaaccta aacctgatcc gatattatgg acccatgtcg agacattcca
     3481 cgaagattca tgggtattga tactgaacaa acctgtaaag atacaatcac ctataccata
     3541 gaacgcgatg gctgctgtaa ctagggtagc taacacacga gatgtactta caaatgcagc
     3601 atacaatgca ggcaatgaca ggatgaaaaa gatccctgaa accacagacc aaataagaaa
     3661 cgcttttctt acaggactgg aaacctctcc aaatacactg atcacgctct tcatttgatc
     3721 taattcagga taatacaatc ctaatacgta cggagtcaaa aaatcactca gcacgcctaa
     3781 taataaaaag aaaaaaccaa atttacgtaa aaaatccatg atacgcctcc aataacaatt
     3841 acctatgctt ttaattgtta ttataagcga ctttatcttg atttaacaga aacctctatt
     3901 tacacgaaca tctatataac tcattaaaaa ctcgaatcat tttaaaaata ctaaatatct
     3961 aacgttcaac gttcacttaa tccatctaaa caatctttca atttgatttt ttccccactt
     4021 cttttacgcg cgcctagctc tcctattgca gtaaacaaca gatcacttga cgaatttaag
     4081 gcagtttcca ttgaatcctg gataacaccg ataataaatc caataccgac gatttgcatc
     4141 gcgacatcat tagagatacc aaacaaacta catgctaatg gaatcaataa cagtgaaccg
     4201 cccgcaacac ctgaagctcc acaagcagct aaagcagaca aaatacataa aaggactttc
     4261 aaaacaaaag gtgcttcaat ccctaaagaa tgtacagcag tcaacgtcat caaggaaatg
     4321 gtaatcgcgg caccgcccat attgatcgta gcacctaacg ggatcgatat ggaataagac
     4381 tcttttgtca atttcaatct ttcagccaac atcatgttta tcgggatatt tgcggcagaa
     4441 cttcgggtaa agaaagcggg aagtgcgctt tctttcaaac aaaagaaaat caatggatag
     4501 ggattttctt taataaacaa aaacgtgagg aatgggtaca caactaatgc gacaaacagc
     4561 atcgtaccga tcaaaacaag taaaagctgc agatactctg ccaatccagc tattccagtc
     4621 gtagcaattg attgataaac caatcctaaa atccctatcg gagcaaatgc aataatcact
     4681 tgtacgactt gtgacaacgc tatagatatc tgatccacca actcttttgt cgattctgaa
     4741 cgtgctcgaa aagctagtcc caacaataca gcccagaata agacgccaag gtaattcgca
     4801 tcaataagag attgaacagg attttgtgtg acattcgtca acatagtaga taaaacactt
     4861 tccaaacttt gcggtgcttt ttcagatact gtttcttgta aagtaatagg aacagtaaaa
     4921 attgaactta caataactgc tacaagtgca gaaagcaatg ttcccactaa atataagatc
     4981 aaaataggct tcacgaatgt cttattccca attttatgct tggcaattga cgccatcgtc
     5041 aagaaaaaaa ccagaatagg tgcgattgcc ttcaagcaac tgacaaacaa cgttcccaat
     5101 attgaaataa atgtccatgt ggggaaaaag ataccaaaca atattccgac taaaatacca
     5161 acaacaatac gttgaactaa cgacatatcc aaaaacttct ctaacaaatg accacccttt
     5221 cacaatttta acaatcattg tatcatttta tgcaaagaaa ctaaaggtat aattttctaa
     5281 aaattctaac aatacaaaca accatttctt gctaattttg tactttttct gtctacacgt
     5341 tgttttttga gatattctaa gttaggatgt tattaatggg caacttatca ggaaacgttt
     5401 tcttatgttt ttgtccaatt tttttgtgag gtgtttattc ttgaaaaaaa taaagaagga
     5461 gagttatggc ttcctgacaa tctttgtcgc ttgtataatg atggttttac agcgtatatt
     5521 gatttcagca gtcactattc ctacatatgc aacaaaccct ggtcgattct acatctatac
     5581 atttttacaa acttccgttg ttattggtgc aaatttgatc ccactttaca tgggttacca
     5641 atatcaaaaa atcgcccgtt taaaagtttt acattattta agtcgttttg cctttatatt
     5701 cctaatagcc acactagttt gcaatatctt ttttttacgt acaagctggc agcttgaata
     5761 ttcgtgatta ttggcttatc ctaacaccta tcagtcagaa ttactttact tatgctgttt
     5821 cttgtacttt gcttttttgt agtattcctt atacagttgg atttttaaat aaattatcga
     5881 aaacaacaat taaatatcta ctattatttt taacaattgg attagttggc tgctctactc
     5941 tatttaataa agacccgttt gcattacaga atggacagag tattttatgg attttttatt
     6001 tatttttaat gggttatggt ttgaaagaat ggaactggaa agaaaaggtc cgctataagc
     6061 ttcctcaagt atttatcagc ttgattgttt tattcggttt gattattttg atgacacaaa
     6121 tttcactcat catcagagga aatacagata cagcgctgag gttttctaaa ccatattctc
     6181 tcttcgcaat gtattatact ttctcttcgt ttttattttt agaaatgcta tctgataaat
     6241 taggtataaa aggaagagga aattttcttg ctgtattttt gattgtcact caagttatat
     6301 gtaatttccc tttagtttct tatcgcgtat ctacatttat gaaacgtgaa tttccaaact
     6361 cagggaaggc atggctgata aatatcgggc agttttttat ttgctattta ttagcagtgt
     6421 ccctcctagt tatcttttta ttttatatac aaaaaatccg tttcattcat cgtttcatcg
     6481 aatacttcgc ttttgattcg attgaacaat taactcagcg ttggaaaaaa agaattcatt
     6541 ggctttttgt tcataaaagt tattttttag ttgcagcatt tttttactgc tttaccttcg
     6601 tgcagatttt cgttttagaa ccaaaagaag gttggaaaga aactatccag gttgccttaa
     6661 aaatatttac tcagcgacaa gcacccatga tcctgacaat catcattatt atgggatttt
     6721 tcttcttact attgttgatt tccaatcgtt tttggtacgc cttgactgct accttgatca
     6781 ttaacttact gctcactatt tcgacagtaa tcaaaatgga aatgcgggaa gagcctgtct
     6841 ttccttcaga tttaaaaata ctgaccggat tgtcagaact attatcgatg gttagcccag
     6901 tcttattaat cgtgggcgga ttgatccttc tcctattatt gattactagt attattgtac
     6961 aacgtagact acaaaaacag tattccttga agattcattg gaaacgtcga tttatcagta
     7021 tcgctgtatt attaggatgt ttttcgggtg tctttttcat taatcacaaa aattcgcctt
     7081 ctttcttgct gtttaattta tttaaagtaa acaagacttt ctttaaccag caaggcgccg
     7141 taaaagataa cggaccagtc attcaattcc taaacaatat cgacattaaa atcatggaag
     7201 aacctgctgg ctattcgaaa gaaaaaatta atggaataat gaaaaagtac aacacaaagg
     7261 cagatgaaat caaccaaaca agaagtgact ggttaaacaa tcagacgatc gttctcaatt
     7321 taagtgaaag cttcagtgat cctgcacgtg tccctaatct gacagtacct acagacccta
     7381 ttccttacat caaaagcatt ataacagaag gaacaggagg attgatgtta tccgtcggtt
     7441 atggtggcgg aacagctaac atggaatggg aaggactgac aggcttgagt atcagtaacc
     7501 tgtctgcttc gttagttaca ccttataccc agctagtgga gcgtcagaaa ataagtccaa
     7561 atattaccga tctattcgat gaaaaaatag ccatccatcc ttttacagct gctctttatc
     7621 gcagaaaaca agtgtttgat aaatttggtt ttgacaggtt ctattattta gacagtccgg
     7681 ataaattaac ttatacggat aaaatagaac aaagcccacg catatcggat gattcagcat
     7741 acaaagaaac cttgaaagct ttacaaagca atacagaaac gtcacaattc atccaattat
     7801 ccactatgca aaaccatatg ccttatgatg attactatag tgaattgaac tacactgctg
     7861 aaggaactgc tgtcattcct aatagaagaa aagaattaca aacttatatg caaggccttc
     7921 actataccga tacagcagta aaaaaattca tccaagaaat cgacaaaatc gataaaccga
     7981 ttacctttgt tttttatggt gaccatttac ccgcaatcta tagtgggaat gattcgaaaa
     8041 aatatggatt agaacagcac cagacagatt atttcattta taacaacaag tatagtcgtg
     8101 aacaagcagc tacgttaaat aaagaagttg ttgctcctaa taactttggt gctatggctc
     8161 ttgagcatgc gaatatcaaa gtaactcctt actatgcgtt gttgacagaa gtatctaatc
     8221 atctacctgc attaacaatt gatcctacag aaagcttgtc taatcgtttt aatggaaaac
     8281 aggtctttgt tacagaggat agtcaaatta tccaagaaaa aaatttaact gagaaacaaa
     8341 aagaaattct agaagattat cgtctgatac aatatgatct tgttgcaggt aaccagtaca
     8401 gtgcaacatg ggcgacacaa aaaat
//
LOCUS       DAZUJR010000104         8312 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.107, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000104 DAZUJR010000000
VERSION     DAZUJR010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8312
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.107"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(105..629)
                     /locus_tag="ACG804_002537"
     CDS             complement(105..629)
                     /locus_tag="ACG804_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HFS4833420.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="ACG804_002538"
     CDS             complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="ACG804_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HFS4833421.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(1218..2198)
                     /gene="pta"
                     /locus_tag="ACG804_002539"
     CDS             complement(1218..2198)
                     /gene="pta"
                     /locus_tag="ACG804_002539"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HFS4833422.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(2351..3031)
                     /locus_tag="ACG804_002540"
     CDS             complement(2351..3031)
                     /locus_tag="ACG804_002540"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFS4833423.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            3157..4026
                     /locus_tag="ACG804_002541"
     CDS             3157..4026
                     /locus_tag="ACG804_002541"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFS4833424.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            4052..4567
                     /locus_tag="ACG804_002542"
     CDS             4052..4567
                     /locus_tag="ACG804_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HFS4833425.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(4614..5177)
                     /locus_tag="ACG804_002543"
     CDS             complement(4614..5177)
                     /locus_tag="ACG804_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4833426.1"
                     /translation="MIRFARKEDAPEIAPLILVILKDMELPFLKQTGEQKTLEILEEA
                     ITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKYQLDASTRLFI
                     DKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLSVDEKNPKAKK
                     LYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(5232..5411)
                     /locus_tag="ACG804_002544"
     CDS             complement(5232..5411)
                     /locus_tag="ACG804_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833427.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(5488..5997)
                     /locus_tag="ACG804_002545"
     CDS             complement(5488..5997)
                     /locus_tag="ACG804_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833428.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(6093..6473)
                     /locus_tag="ACG804_002546"
     CDS             complement(6093..6473)
                     /locus_tag="ACG804_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFS4833429.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            6803..7552
                     /gene="pnuC"
                     /locus_tag="ACG804_002547"
     CDS             6803..7552
                     /gene="pnuC"
                     /locus_tag="ACG804_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HFS4833430.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(7873..>8312)
                     /locus_tag="ACG804_002548"
     CDS             complement(7873..>8312)
                     /locus_tag="ACG804_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFS4833431.1"
                     /translation="KKAEGSPCFLLYQTFPGIGALTAALLLGELGDITRFKTHKQLNA
                     FVGIDIRRYHSGKYTGQDRINKRGNPKARKIIFFTIRNMIRQQRAAPNHIVDYYYKLK
                     KQPIPKKDKVATVACMNKLLKCMHAMVRAHTEYDYAYAVSVDH"
BASE COUNT         2374 a         1714 c         1500 g         2724 t
ORIGIN      
        1 tattcaaaaa aaatggactg cgacacgact tttgtcacag tcccttcgtg tgtttttctg
       61 ccttctcaaa aggatgacag tttctcactc ttttcctatt tcttctattc aatcaaataa
      121 ctcattttat atacatctaa aaattcacct agatctgttc ttgcccctct aggcatgacc
      181 gcttcgattt ggaagcccat ttttcggtaa aggtgtacgg ctctttcatt acgaacttga
      241 acgtcaagct ccaatcgaaa aagtacaccc atttccttcg cccaactgat gatttcttct
      301 agcataagag tgcctagtcc cattccccaa tattcctgca gaatactgat accgacttct
      361 cccacgtgag acaaacgaaa ttgactgtct gccttgacag atgctgttcc aataatcgtc
      421 ccttcataga ttgcaagcag caataaatta ttattgcttt cgtatatata atccaactct
      481 tcttctaagg tttctggtgg taacaggagt tctgcttcat ccaaaactaa aaattctgtc
      541 tccttattaa cttgtcccat catcaaaaga atgtcttttg catctcctgg cactgcttcc
      601 cgcaagatga tcccaacttc ttcactcatg attttcagcc catttttcta gaattcgctg
      661 tttgaaggtt tcactttgct ccccgtatga gattagtttc acataccgct tttctaaatc
      721 tgtatcactt ttttctaaaa tcagttccaa ataatcctcc ggcagtgctt cttctaatag
      781 atttccccat tcaacaacgg aaagcccatc accttcaaaa tattcatcta accctaaatc
      841 tgctccgcta gctgctaccc gataaatatc catatgatac aacggaatcc gaccttgact
      901 atattctcta ataatcgtgt atgtcggact tttgatcatt tgcgttatcc ctaatccttg
      961 ggcaattcct ttcgtcaacg ttgttttacc cgcacctaga tcaccagtca atatcagatt
     1021 gtcacctggc attgcggaat gaccaattgc ctctgcgaat tgttctgtca ttgttaatcc
     1081 tgatagttcg atcatttttc atcttctccc gctcttcttt ctttttgcca gtatatcgcg
     1141 taatgaagtt tttttaaaga aaaaatgaac tagtcaagaa cagcagctgc tgtttttggc
     1201 tagttcgcgt gtatttgtta atcaatcaat gtttgtgctg ctgtgataat cgataattta
     1261 tatacatctt cttcatttgc tccacgagac aaatcagaaa ccggtttgtt caagccttgt
     1321 agaattggtc cgattgcttc aaagttaccg aaacgctgag caattttata gccgatattt
     1381 cctgactgca attctggaaa tacaaagact gttgcttgac cagctacttc tgaatctggc
     1441 gctttcagtt gtgcaactga aggaacataa gaagcatcaa attgcaattc gccgtcgatc
     1501 atgtattgtg gcgctagttt tttagcgatt ttagttgctt caactacttt gtctacttct
     1561 ggcgatttcg ctgagccttt tgtcgagaag ctcatcattg ctacttttgg ttcgatatcg
     1621 aacaattctg ctgtttttgc agaatctacg gcgatttcag ccaattcttg cgcagttgga
     1681 ttcacgttga tcgcacaatc cgaaaagaca tatttttctt gatctcttcc acgtaccatg
     1741 atcatcgctc cgcttgtccg actgatgcca ggctttgttt tgatgatctg aagtgctggg
     1801 cgaacagtgt cgccagtcga atggatcgct ccagagacca ttccgtctgc aatccccata
     1861 tacgtaagca tcgtaccaaa gtaattcaca tcttttaaaa tcttttctgc ttgttctttg
     1921 gatgcctttc catttctacg ttcaacaaaa gtatccacca tttcatccca cttatcgtaa
     1981 ttatcagggc tgatgatcgt aaagctagat gttttgattc ctctggcatg cgctgcattt
     2041 cttatttctt cttcgttccc tactaaaatg ggttccacaa gttcttctgc tttcaaccgg
     2101 gcagctgcgc ctaaaatacg agcatcagta gcttccggga aaacgatttt gatcccacgg
     2161 cgaacaattt taaatcttaa actatcaaac aattccacaa gatgacctcc agacgttttt
     2221 atatgtatta tcatacacta ttccagaaaa aaagaacagt ttattttatc tgtatcagtc
     2281 aaaaatgctg gaaaaattaa gtttttcaca tacaaagcga actgcactat aacaggaaag
     2341 cgctgtttta ttacactgtt tcaggcagtt gccaatcaat cggttcttct cctaacgcaa
     2401 ggagcgcatc attcgttttc gagaagggtt tggaaccaaa aaagccacga cttgcagata
     2461 acggactggg atgtggagat gttatgatga tatggcgact cttatcgatc attttgattt
     2521 tttcttgtgc cggttttccc cacaagataa acacgattgg tttttcccgt tcatttaatt
     2581 tttcaatgat cgtgtctgtt aatctttccc aacctttccc gcgatgagaa tacgcttgcc
     2641 cttcccgaac ggtaagaacg gtgttgagta aaaggactcc ctgtttagcc catgacacta
     2701 gatttccatg ttgaacaggt gcgattccaa gatcatcata aagctcttta tagatatttc
     2761 ttaacgatgg cgggatcttt acgccaggtt gcacagaaaa agataagcca tgagcttgat
     2821 tttctccatg ataaggatct tgtcctaaaa tcaccacttt aacttcttca taaggagtca
     2881 attccaatgc ttcatagata tgatacatat ctggatggat cttttgggac gcatattctt
     2941 tttttaaaaa ttctcttaga tgcagataat aatcttttga aaattctgag gacaaaactt
     3001 cttgccaact gttatgaatg atttctttca aaaactccac ctcctaataa aaagaataac
     3061 tcacattttc ttcaatcaca agggacaatc ttcaccctca gcacttgatt aatatggtaa
     3121 actaggaaca agaagcagaa aggaacgata atcattatga tcaaattaat tgcatcagat
     3181 atggacggca cattattaga tgcccatatg agtgtttctc ctgaaaatgc cgaggcgata
     3241 cgttttgcaa atgatgccgg tgttgagttc atggtcgcta ctggtcgaaa ctatcaagaa
     3301 gctcgcgcag ctttagatga ggtaggaatc gattgtgcga tgatcacttt gaacggggca
     3361 caggtatttg ataaagaagg aaattcattg tttaccgtgt cgattccaaa taatcaagca
     3421 atctctgttt tagatattct agatgctaac ggtatttact atgaagtagc aaccaacgat
     3481 ggtctttatt ctgaaaatca agcgaaacga attgaaagtt ttgcttccat ggtggctacc
     3541 catttacctc accttacgta taaaatggcg attgccatgg cctcagctaa gctggagtta
     3601 ttgcacatca catacgtgga cagtattcgt gctattttgg aagaaaagaa tctggaagtt
     3661 ttaaaaatta tttgttttca tacagaaggg ccagctgtat taggtccagt tggaaagcag
     3721 atttctcttt taggcgatct agccgttact tcctctggtc aaaacaatat cgaagtgaac
     3781 cataaaaacg ctcaaaaagg aattgctgtt gcccatgtcg ctcacgagcg tgggatttct
     3841 ttagaagaag tcatgacgat tggcgataac ttcaatgatg tcagcatgct gcaagtagca
     3901 ggagtcagtt tcgcaatggg aaatgcagaa atcgaagtaa aagattatgc caaatataca
     3961 acggacacaa accttgaatc tggcgtagga aaagccatat tgcgcgcgat tgcagaagac
     4021 ttgtagtttt atctagaaaa gagggatata gatgtcagaa tttttcattc aggaaaagca
     4081 gcttggacgt gcaactcgga caattgtcaa aaacgaaaaa ggacattccc tgtttttgat
     4141 ggttggtcgc tggggaacaa agggcgatgc attgtctctt tatgccatga atggcgatct
     4201 cgttgctcac atcaagcaga taagcctgac attcggtacg cgttttgagc tgtataaaga
     4261 gttcgaaaag gtgggaacca tgcagaaaat attcaattgg cccggtgact tttattatat
     4321 tcgtagactt cactggacag tccaaggtga tatctataat catcaatatc aaatccatca
     4381 tttcaatcag caaatcatga aaatggataa agcaacactt ttttcaggag attactatgt
     4441 attggatgtc tcaaatgatg aagatgctcc agtttgtatt tgtattgctg cggttttaga
     4501 ttactggctc taccgtaaag acaaaagtcg cgataagcct gtttcttacc gacttaactt
     4561 aagttaaaaa gatgtacctg aaatgcggaa atacgcattt caggtacatc tttttagata
     4621 ttcttttgca tatgatcata aagatgacca ctgatcatcc gctgaccgac aactttgaag
     4681 tcatggcgtt cgtataattt tttagccttt ggattttttt catccacact tagaccgatg
     4741 acggagcgat tagctttctt cgccaattta ggtaatgctt ctaataatcg cgaaccgatg
     4801 ccttgtcctc taaaatcttc tgatacactg atagagtcca aataccattc gttgggaaac
     4861 gtttctttat caatgaacaa acgtgtagac gcatctagct gatatttctc taagataggt
     4921 accagtggct gatcgatgat tgattcttct tcatctgtat aaccgtaagc aactcctgca
     4981 actttaccgt ctatttcttc tacgatacct cgtgaataac tgtaacgata atttggatca
     5041 gtgattgctt cttctaaaat ctctaaagtc ttttgttccc ctgtctgctt caaaaatggc
     5101 agttccatat cttttagaat cactaagatc aatggggcga tttctggagc atcttctttt
     5161 ctcgcaaaac gaatcatagt ttcctctcct tttctccatt ctaacatgca gaaaaagaaa
     5221 tcgcaaaatc gttattttaa aaaatcttca atcttttcag taatgaaata accatgagta
     5281 acgattcttg ccgcttcagt tcggcaataa gggcagacga ctggcatttc tttatcatta
     5341 tgttcgacta cattattgac ttcttcgtat gcaaattttt ttccgcaatt agggcatttc
     5401 attttttcca tgttatctca acttcctttc atctttactc tcttagctta ctcttatatt
     5461 gtaaaaaaga gaagcaatat ccttcttcta tgcagatatc catacctgac ggtcctgttc
     5521 tccatctatt aatcggactt tataataagg acgttcatct ttgactagaa gtgtccactc
     5581 tttcactttt gcttttttcc cgtagtagct gactgcttcc ttcatcgctg cttgcggttg
     5641 tttgaactct tccgtttttt ctatatcaaa aagatgttct gcggcctttt ccgtgtcatt
     5701 tcgtacggtt gttttcccag tggatggatt gactgctatg acttgtcctt cacaaaaaaa
     5761 ctggtattca tatgttgcat tcgtaggatt ctccaaatct ttttcaactg caaaatgaat
     5821 agcagatatg ttatgttctt ttgtttcgtt ttttacgatt gctgctgctt ttttcaatga
     5881 gatccgatat tcctggtcac taatatcatc catgtgaaaa gcggcattga gcagtcccgt
     5941 cataccggta atccctatta cgatgagggc agcaacacca aacatcattt ttttcattct
     6001 tcattctcct gtttcttttt tttaaagaat atcaagaaat gaacgaatga aaaatcgaat
     6061 gaaacgaaaa aaaagtgaca attttgttat ctttattcgt gcagttctaa tggcaatccg
     6121 tctggatcaa agaaaaacgt catttttttt cctgtaaagg tatcttctct aatcggttct
     6181 gattcgatcc ctaaggactg caattctgca attgtttctt caatatcgtc tactttgaaa
     6241 gcaagatgac gcaagccaca agcttctgga tagtttggtc gttgtggcgc attagcaatt
     6301 ccaaaaatct ccaattcagc acttcctagt ttcagatcta atttatagtc atctcgttct
     6361 ttgcggtaat tttctctgat tacttcaaat cctaatttat taacataaaa atcacgtgat
     6421 ttctgataat ctgaaacaat gatggctata tgatggatcg ttgtaaggtt catatgagca
     6481 ctcctattct tcgtttaagc tcggatctat attaatctcc agttccattg taaatgtgtc
     6541 agattgaaaa aaatagctgt ttttcctttt tataagaaaa aaggcaaaaa aaacagaaag
     6601 taggtcctcc aagacactct tcctgttccc aatataataa atgaaagtaa gaaattatat
     6661 tttcaagaaa acaaacagaa aattatcata acacaaatta tttataattg aaagactagt
     6721 tttttttcaa gaaaagcata caatagattg tgttagtaaa tacagaacac actacattta
     6781 gtgtcttaag gagtcctcat acatgaagtc atattttcag tttttagctc atcagctaaa
     6841 aggctggccg caacaaaatt attatctttt ctttttcagt cttggctgcc aggtcatgac
     6901 tcttgtcaat agtcccatca cttggctgtc cgttattaca tttatcggta ccacgcttgg
     6961 tgtattgtgt attttatcca tcaatgcggc aaaatcagtc aacggtattt taggtatttt
     7021 gtctgcgatt tgttttatta tcgttgggtt ttcagcaaag aactatttaa gtatcggtga
     7081 acagattgct tatatgatca cattggatat ccccgtattg ttaagtaaag aatggaatca
     7141 taatatggct tcaaaaatcc gaaaattcac tggaaaaagc tggtttatcg caatcatcag
     7201 tactttcctt gtctatcttg tttcaggatt cctgattggt cgttatacag atgatcctcg
     7261 gccgtgggta gatgccattg ctttttctat tagcttgact gctggtatca tcagtttctt
     7321 gcgttacaac aaccaatatt actggtggtt agcttcaggg cttgctcaaa tggtcctttg
     7381 gtatatttca tttacgcatg gatctgcaag tttggcgatg ttcgtgaaca gctctgttta
     7441 cttgctgaat gatgtccttg catttaccgt ttcaccttgg tataaccaaa aagaacgtga
     7501 acgtatgcaa aaaatggaag aagaatacta caacgcacaa caacacgcat aaaaaaactg
     7561 agcgtgggac aaaagtaaag aacacttttg tctcacgctc taaacacgta taaacggcgg
     7621 aatcagaagc aactccttcg gaaataagct gaaattcaca aaaatttgaa aagcaatttt
     7681 cgtgaatttc ttcttatttc ttggagttaa acgcttctgt cccagcctct atttcctacg
     7741 attagtcaag taaaaggtgc aagaaaaata gctcgtaaac gaaagcgaca aaatcaaagc
     7801 acaccaaata aagccccgtt cgtaaaaaat tttcgatctg ggcaaagaag tggtatactg
     7861 taagtggttt agttaatggt ccactgagac cgcgtacgca tagtcgtact ctgtatgtgc
     7921 cctaaccata gcgtgcatac atttcagaag cttgttcata caagcaactg tggcaacctt
     7981 atctttctta gggataggtt gcttttttaa tttgtagtaa taatcgacaa tatgattagg
     8041 agctgcgcgt tgctggcgaa tcatatttcg aatggtgaag aaaataattt tccgtgcttt
     8101 gggattacca cgcttattga tgcggtcttg gccagtatac ttacctgaat gataccgtcg
     8161 gatgtcgatt ccgacaaagg cattcaattg tttatgggtt ttaaatcgtg tgatatctcc
     8221 taattcaccg agcaataaag cggctgtgag tgcgccaatc ccagggaacg tttggtacaa
     8281 caaaaagcaa ggagagcctt cggctttttt ga
//
LOCUS       DAZUJR010000105         8257 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.108, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000105 DAZUJR010000000
VERSION     DAZUJR010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8257
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.108"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(212..1660)
                     /gene="cls"
                     /locus_tag="ACG804_002549"
     CDS             complement(212..1660)
                     /gene="cls"
                     /locus_tag="ACG804_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFS4833432.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGEIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHTTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            complement(1812..2696)
                     /gene="ftsX"
                     /locus_tag="ACG804_002550"
     CDS             complement(1812..2696)
                     /gene="ftsX"
                     /locus_tag="ACG804_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HFS4833433.1"
                     /translation="MIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFMAVI
                     MNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELKKIQ
                     NEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSDRIF
                     QIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRWPFF
                     LEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMVGIG
                     VIIGSLGSIISMRRFLKF"
     gene            complement(2689..3375)
                     /gene="ftsE"
                     /locus_tag="ACG804_002551"
     CDS             complement(2689..3375)
                     /gene="ftsE"
                     /locus_tag="ACG804_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HFS4833434.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            complement(3480..4581)
                     /gene="prfB"
                     /locus_tag="ACG804_002552"
     CDS             complement(join(3480..4508,4510..4581))
                     /gene="prfB"
                     /locus_tag="ACG804_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HFS4833435.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            complement(4707..7241)
                     /gene="secA"
                     /locus_tag="ACG804_002553"
     CDS             complement(4707..7241)
                     /gene="secA"
                     /locus_tag="ACG804_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HFS4833436.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            complement(7463..8014)
                     /gene="raiA"
                     /locus_tag="ACG804_002554"
     CDS             complement(7463..8014)
                     /gene="raiA"
                     /locus_tag="ACG804_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HFS4833437.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            complement(8142..>8257)
                     /locus_tag="ACG804_002555"
     CDS             complement(8142..>8257)
                     /locus_tag="ACG804_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="HFS4833438.1"
                     /translation="KILIIDDVYTTGQTLFHAADCLQNAQPKIIRTISLAR"
BASE COUNT         2202 a         1819 c         1440 g         2796 t
ORIGIN      
        1 actctcatgc tatactggct ttgaaatgtg tctcttttaa tagcatatat tagcttattt
       61 cttgctttcc ccaaaaaaca agagataccc caaagttaat ttcgctcatg cgagacgctt
      121 tctccatttc tgacgtactc tcagaaatgg ccccgttaaa aaaggacacg agatctccat
      181 ctgttgatgg ttctcatgtc ctttttatgt tttaaaggag cggcgaaatc aatcttgcta
      241 atccttcttt catcttgatg attattcctc ggttttcata catttctttt gtgagatgcg
      301 tagaaatttt cgagtcttca aaaaaagctt ttcttacacg tgaagccatt cgttcatcat
      361 aaaccagtgt attgacctca aagtccaagc gaaatgaacg aacatcgata tttgctgagc
      421 caactgaaac aatgccacca tcgataatca tcgtctttgc atgaataaat ccattctcat
      481 atgtttcgat ccttgctcca tactcgatca gctctgcagc gaaagaatac gttgcccagt
      541 aaacgagaag atgatctggt ttgttaggta tttggatatg aacttttacg cctgaaagaa
      601 gagccaactt cagtgcttca tgaatcgatc catccggtat gtaataaggc gtttggatca
      661 atatctcccg tttggctaac gaaatcattt tcaaataagt cattttgatt tgttcatgtt
      721 cggtatctgg tccgcttgtc acgatttgaa cagctatatc accagtagtg tgaatggacg
      781 gaaaaaattt gggagaatag cctacttctt ttgtatgctg agaattccag tccatcaaaa
      841 aacggttttg caaggtatac accgcttctc cgtaaatacg caaatgattg tctcgccaat
      901 aaccaaattt ctttaccaat cctagatatt catttccaac attgaaccca cctgtatatc
      961 cgatttcccc atcaataact acgattttac gatgattgcg ataattgatc cgaggattaa
     1021 tatacggaac aaatagagga aagaaaaatg cgacttctcc gcctgctttt ttcaaattct
     1081 gaaaaaagct ggaagaaact tgtgtggaac cccatgcatc aagaaggact ctgactttta
     1141 cccctcgtct tgccgcctct gtcaatgcat ctcgaacttc ttcacctaat gcatcactgc
     1201 gataaatata atactggaag tggatatggt cttctgcctg cttgatatct tcaatcagcg
     1261 catcgaattt ttcacgacca tctgtaaata aagtgatttc atttttagtc gtatagagcg
     1321 tactttcaaa taccgtgagc atatagatca attgtttcac atctacttgt ccagtaggcg
     1381 gatgaggata aagccctcgc atcaatgcct gtttgtcttc ttcaatttcc aggttcttac
     1441 cgattttccc ttggatcttc aaatcaaaga ttttctcttt ggaaatccct cttcctaaaa
     1501 aaatatataa aataaatcct acaactggaa tgaacatcaa aacgagcagc catgcccatg
     1561 tttgagcagt ttcctttctt tctcgaaaaa cgatgataaa ggaaagcaaa atattcataa
     1621 tcaaaaggat cgtaaaaaaa ttgtcaacga taattttcac ggcttcacct cttcttctac
     1681 caacttaaga atacccaagt tgttttttaa agtaaaggga aaaaagccgc ttccttctat
     1741 tctcctagcc aataaaaaaa gaaagctgga acgaaactgt ccaactttct cattttattt
     1801 atattgtggt attagaattt caagaaacgt ctcatagaaa tgatcgagcc aagtgaacca
     1861 atgatcacac caatgccgac cattaaaaga ttgattttcc aaacgatatt ttgtggatga
     1921 atcaatgaat aatgggaacg taataatgat ggattgatca attggaaaaa ccatgcataa
     1981 ccaaatgtga tgatcaaaat tggaagaatt gcaccgatca gaccgatcca gccaccttca
     2041 aggaaaaacg gccagcgaat atatccattt tttgcaccga ctaaacgcat gatttgaatt
     2101 tcacgctgtc tagacaaaat cgtgatccga atcgtgttcg aaatgagaaa catcgctacg
     2161 aacagcagca atgccgctgc aactaatccc catgtccgaa ctgcaccagc gatttggaaa
     2221 atccgatctg aggaagctcc accgtaatca gaacgagaaa cattcttcaa atctgctgct
     2281 tcttctgcta cttgttttgt ataagaagga tcagtagcac ttactacata cacatcatat
     2341 aacgggttat tgtcaccttc aaacaatttc caggaatcac ccatttcgtt ttggattttt
     2401 ttcaattcct gttctttgct tgaaaattca acttttttaa catgatctaa gtcattcaat
     2461 tctttttcta gctttttcat ctcttcgtct tttgtaccga tatctacgaa tacagataca
     2521 tcaacgtttc cttctatatc ctgagctaat ttagttgcat tcatgataac tgccatgaat
     2581 acaccgacta aagtcaacgt gatcgttacc gcactgactg aagcaactgt catccagccg
     2641 ttacgtttca aactcttgat actttctaat aaatggcgga aaaaggttct aatcatcgta
     2701 tccatattcc ccttccgctt gatctcgaat aatgcggccg ttttcgatag caattactcg
     2761 gtgccgaatc gtatttacga tcgtactgtt atgtgtagcc atcacgacag tagttccttg
     2821 ggcattgatc cgatctaata atttcatgat ttcccatgag ttttctggat ccagatttcc
     2881 tgtcggttca tccgcgataa gtactttagg cgtattcacg attgcccgag caatagagac
     2941 acgttgctgt tccccaccgg ataattcgct aggaaagact cgaactttgt gtttcaaacc
     3001 aacaaggtcc agcacttcca ttactcgttt tttgatatct cgaggttttc tgccgataac
     3061 ttgcatagcg tacgcaacat tttcatatac tgtttttctt ggtaataatt tatagtcttg
     3121 gaacaccacg ccgatttctc tgcgtagata aggaacttcg cggtttttga ttgctattag
     3181 atcatgacct gcgacgttca aagttccttt tgaagctttt tcttctcgat acatcaattt
     3241 gatgaatgta gatttaccgg ctccagacgg accaaccaca tagacaaact ctccttgttc
     3301 gatgacaatc gagagattgc ggatagcggt cgtaccattt gagtacttct tcattacatc
     3361 cttcatttca atcatggcgt tctctccata tctttttcag tctttagcta ttatagcatg
     3421 gcaatgtttc aacatgcttg caaaatctta caattttatt tcaatttaac aatgggttct
     3481 tattgtagat gcatttttaa atagccgtca ataaataaat caaggtcacc gtccataact
     3541 gcttggacat ttcctgtctc tacgtttgtc cgatggtctt ttaccataga atagggatgg
     3601 aaaacataag aacggatctg tgaaccccag ccgatttctt tttgttctcc tcgaagtgca
     3661 gctgcttctt gttctttctt ttccacttct aattgataaa gcttagcttt taacatcccc
     3721 atcgcttgct cacggttttt caattgtgag cgttgtgcct gactagctac tactgttcct
     3781 gtaggcaagt gagtgatccg tacagcagat tctgttttat tgatgtgctg accacctgca
     3841 ccacttgctc ggtacgtatc gattttcaaa tcatctggat tgatttctat atcgatcgtt
     3901 tcatcaagct ctggcatcac atctaccgaa caaaaagaag tatgacgtcg tttcgctgag
     3961 tcaaaaggcg aaatccgtac aaggcgatga acaccttttt ctgattttag ataaccaaaa
     4021 gcgttatgtc ctttaatcag cagggtcaca ctcttgatcc ctgcttcatc acctgcttga
     4081 taatctagtg tttctacttg atagccatgc tgctctgccc aacgtgtata catacgtaaa
     4141 agcatgctgc cccagtcttg ggactccgtt ccgccagccc ctggatgcaa ttcgacgatc
     4201 gcattgtttc gatcataagg tccgtctaac agcatagata attcatacgt cttcattttt
     4261 tcatctaatg cattgatacg tgtttctgct tcttcttgca ttgctgcatc aggttcttct
     4321 tgcagcatct ccaccatcaa ttcgatttct tctagttctt cggcaagaga atggaattgg
     4381 tcataggttt ctttattagc gttattttcg ctgatcactt tttgtgcggc ttcgctgtca
     4441 tcccaaaaac caggttcagc catttttgct tctgcttccg cgatgtcttc ttccagctga
     4501 tctaagtcaa agagacctcc tgaaacttgt gaccttttcc tgcatttctg tcaggagatt
     4561 tcgaatttcg gatatttcca tgttttttcc ttctttcact atactttttt cattatatct
     4621 agtctaacag aatcagcaaa taacagaaag aaggtgagac gaattcttaa aaaaagaatt
     4681 tgtctcacca atcctgctgt cagaaattag tttgcatttt ttccatgaca gttcttatat
     4741 tttttcccgc ttccacaagg acaaggatca tttcttccga ccttattcac atggattggc
     4801 tgttttttcg cgctagtatt actattttct ttggcatctc cgtcttctga gtgagaagct
     4861 gttccttgag aaacctgttc acgctgtacg ttttgacgga tctcagcttt cataaagatt
     4921 cgagtgactt catactcgat ggcgcctacc atatcttcaa acatcttata gccttctgtt
     4981 tgatattcga ctaatggatt gttctgtcca taagcacgta agccgattga ctgacgtaat
     5041 tgatccattg catcaatatg gtctgtccat ttagagtcca caacacgcaa gatcacgact
     5101 ttttcaaatt ccaacagttg ctctggacca tttagttgag ccgctttggt attaaatact
     5161 tcttgtgctc gttcgtttag atactctttg atctcctgag ctgtttttcc ttcgatatct
     5221 gcaagagtaa tgctatcttc atggacaaga gtactgccgg caaaatcgat gatactttcc
     5281 aaattccaat tttctttctc taattgtgta tgcgcatcta ctacacgact gattgtccgt
     5341 ttgaccatgt tcattagtgg cttggataag cttttttctt ccatgattac ttcttgtcgc
     5401 tgtttataga ttacttcacg ttgttcacgc atcacatcat cgtattgtaa gacgttttta
     5461 cgtgtgtcat agttatttcc ttctacacgt ttttgtgcag attctacttg tttcgtcagc
     5521 atcttgcttt ggataacagc atcttcctca ccgatcttca tccgatctaa gaaagctttg
     5581 attcgttctg aaccgaatcg tttcatcaaa tcatcttcca atgacaagta gaactgtgac
     5641 ataccagggt ctccttgacg tcctgcacgt cctcgaagct ggttatcgat acgacgagat
     5701 tcatgtcgtt ctgtcccgat aactgctaga ccaccaagtt ctcttacccc aagtcctaac
     5761 ttgatatctg ttccccgacc agccatgttg gtagcaatcg tcacagcacc tttttgacca
     5821 gcattcatga tgatctctgc ttctttaaag tgatttttcg cattcagcac ttcatgagga
     5881 atacgttctt gattcagcat atctgataat aactcagatg tttcaaccgc aacagttccg
     5941 actaacacag gttgaccttt gcggtagcga tctttgatat cttgcacgac agcgtggaac
     6001 ttgctttgta atgttgggta aagcaaatct ggacgatcat cacggataac cggacgattt
     6061 gtcggaatct ggtatacttg gatgttataa atttctctga attcttcttc ttctgtttta
     6121 gctgtaccag tcattcccgc aagtttcttg tacatacgga aatagttctg gaaagtgatc
     6181 gtcgccatgg ttttcgtttc gtcttcgatc tctacgcctt ctttagcttc gattgcttgg
     6241 tgaagtccat ctgaataacg gcgtccatcc atgatccgac cagtgaactg gtcaacaatc
     6301 agtacttttc cgtcttggac aacataatcg atatctaaaa gcatgatata gttggctctc
     6361 aatgcttgat ccaagtgatg ggtcaatgca gtattttcaa tgtcgtataa gttatccaaa
     6421 ccgaatgttt cttctgcttt ttcgatccct gcttcggtta aactgattgt ttttgattgt
     6481 acatcgattt tataatcttc ttcttctttc aaacgtttca cgaagttgtc tgctcttgta
     6541 tataaagctg tggatttttc tgcttgccct gaaatgatca gcggcgttct cgcttcatca
     6601 atcaagattg agtcaacttc atcgacaatg gcataattca gcggacgttg taccatttga
     6661 tggcggtaaa cgaccatatt gtctctcaag tagtcaaatc ctaattcatt attcgtacta
     6721 taagtgatat cacaattata agcctcgcgt ttttcatccg aagattttga gttgatattc
     6781 aaccccactg ttaatcctaa gaaattataa agttcgccca tttccgtcga gtcacgggtt
     6841 gctaaatatt cattgacggt aactacgtgt accccttcgc cagtcagagc atttagatat
     6901 actggcatcg ttgcggtcaa ggttttacct tcaccagtac gcatttcagg gatatttcca
     6961 tcgtgaagca cgattccacc catcaattgt acgtggtatg gatataaacc taatacacgt
     7021 tttgctgctt ctcggacgac tgcaaaagct tccggaagta attgatctaa tgtttctcct
     7081 ttttggtatc tgcccttgaa ttcagcagtt tttgcctgta attgttcatc agttaatgct
     7141 gccatttggt cagcgtatgc ttcaactttt tttgcaatgc tatctaaacg ttttagttct
     7201 ttcttatcgt tttcgataag tgaacgaatc aaattggcca tgcgttgtgt aatctccttt
     7261 tccttctgtg tattatccag actatgtaga ctttactttt cattttatca ttagttatag
     7321 ataattgaaa tatcttaagc gtattaaagt aagaacttca taatttattc atatttcatc
     7381 taaaagagga ggaaactcaa aaaaacttgc ggcagctgtc agtagctgct gcaagttttc
     7441 gttgttattt aagtaaggct gatcagtctg tttcaatcag tccgtatttt ccatctttac
     7501 ggcggtaaac gatacttgta ccatttgttt ctgcatcttc aaaaataaag aagttatgtc
     7561 ccagcatgtt catttgtaag actgcttctt cactatccat tggtttcaat gaaaggcgtt
     7621 tcgtacgtac gatatctaat tcagaatcat tttcgttttc gtcctcttca ttgaataaag
     7681 cagcagcatc tgcagtattc atgcccgttt cacgggattt acgattaatt tttgttttga
     7741 atttgcggat ttggcgttcc aatttgtcaa caaccaaatc gatacttgcg tataaatctg
     7801 gagaagtttc ttcggcacgt aatacaagat aaggtaatgg gatcgttact tccacttttg
     7861 ctgttttttc tgtataaact tttaagttca catgcgccgt tgcatcgggt gcgtcactga
     7921 aatagcgttc tagtttgcct acttttttct caacgtagtc gcgaatcgct tcagttactt
     7981 cgatattttc gccgcgtaca ttatatctaa acataaaaat tacccctttc gtctaccaca
     8041 atcaagaagg agaaggacca ctctttccct cttcttaatt ctattatatc gaactctagg
     8101 ttatttgcaa attaaatcgc tatcaaattt ccacatctga ttcatcttgc caaagaaatg
     8161 gttcggatga ttttcggctg tgcgttctgc aagcaatctg ctgcatgaaa aagcgtctgt
     8221 cctgttgtat agacatcgtc aataatcaat atttttt
//
LOCUS       DAZUJR010000106         8195 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.109, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000106 DAZUJR010000000
VERSION     DAZUJR010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8195
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.109"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(1..412)
                     /locus_tag="ACG804_002556"
                     /pseudo
     CDS             complement(1..412)
                     /locus_tag="ACG804_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(614..1009)
                     /gene="panD"
                     /locus_tag="ACG804_002557"
     CDS             complement(614..1009)
                     /gene="panD"
                     /locus_tag="ACG804_002557"
                     /EC_number="4.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004068 - aspartate 1-decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006523 - alanine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase"
                     /protein_id="HFS4833439.1"
                     /translation="MKVTMLKGKIHRATVEQAELDYVGSITVDMNLLEAAGIYEYEKV
                     QIVDVNNGNRFETYTIAGERGTGMICLNGAAARCVSTGDKIILMAYCELNENEVKDHR
                     PKVVFVDDNNKVERVTSYEKHGRLSDIIL"
     gene            complement(1019..1867)
                     /gene="panC"
                     /locus_tag="ACG804_002558"
     CDS             complement(1019..1867)
                     /gene="panC"
                     /locus_tag="ACG804_002558"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004592 - pantoate-beta-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HFS4833440.1"
                     /translation="MVIFKTVNDVRSQVKEWKKQGLKVGLVPTMGYLHEGHESLIRKA
                     SKENDKVVVSIFVNPTQFGKNEDLGSYPRDLERDIEVCTRGRATAIFNPEVEEMYCDN
                     ASTFVNITGLTEGLCGASRPIHFRGVCTVVSKLFNIIPADRAYFGEKDAQQLAVIKRM
                     VRDLNIDIDVVGCPIIREEDGLAKSSRNTYLSLEERSSATILNKSLTLAKEALNNGER
                     DSLKIIEIISKNINTYNLAKIDYVEVVDSLSLQRVNYIEKSVLVAIAVFIGKTRLIDN
                     FTFELQ"
     gene            complement(1882..2709)
                     /gene="panB"
                     /locus_tag="ACG804_002559"
     CDS             complement(1882..2709)
                     /gene="panB"
                     /locus_tag="ACG804_002559"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003864 - 3-methyl-2-oxobutanoate
                     hydroxymethyltransferase activity [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HFS4833441.1"
                     /translation="MKNTAVTFKESKLRNEKLTMLTAYDYSTAKIIDEAGINGILVGD
                     SLGMVCLGHEDTLSVTMEDMIHHTRAVTRGAKNTLVVADMPFMSYQTSVYDSVVNAGR
                     LIKEGRAQVVKLEGGIEVCDKIEAIVKASIPVMAHIGLTPQSVNAFGGFKVQGKDKEA
                     AKELIRAAKAVEKAGAFAVVLECVPTKLAELISKEISIPTIGIGAGAGCDGQILVYQD
                     MLGMYSDFTPKFVKKYANLSEEMNKAFTKYIEEVKDGVFPGPEHGFKISDDVLEKLY"
     gene            complement(2721..3581)
                     /locus_tag="ACG804_002560"
     CDS             complement(2721..3581)
                     /locus_tag="ACG804_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002384409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rossmann-like and DUF2520 domain-containing
                     protein"
                     /protein_id="HFS4833442.1"
                     /translation="MEVIIMNVGFIGAGKVGCSFGKYFQEHKIQVTGFYSKSEDSSLA
                     ASNFTSSKQYLNLRELVDENDTIFITTPDGQIQEVWQEIKNYQIKNKLICHCSGAISS
                     DIFSNIQDYGAYGYSVHPMFSISDKYNSYKKLKKSFITIEGDEKYAKFLCDFFKKLGN
                     STVIVSKENKSLYHAASVVSSNLVLGLINTSVTYLIQCGFTEKMAIEALYPLIEFNIR
                     NIKEKGIIESLTGPVERCDISTIKGHCEVLSDEDRALYMLLSKNVLEIAMLKNINRDY
                     SELEKYLGES"
     gene            3819..4988
                     /locus_tag="ACG804_002561"
     CDS             3819..4988
                     /locus_tag="ACG804_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HFS4833443.1"
                     /translation="MTKFTIEIMQTLLNKGDLDELFQDHLERAINSLLQAELTAFLDY
                     EKYDRNGFNSGNSRNGNYSRTFKTEYGELNLTIPRDRNGEFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMAEISKLIEKMYGHHYTPQTISNMSKLVAEDVLAFKERTLEANYSVI
                     FMDATHIPVKRQTVSKEAVYITIGIRLDGTKEVLGFTIAPTESAYIWKEVLQDLRKRG
                     LEEVLLVVTDGLSCIEESIHSVYPNAQFQQCCVHVSRNIAHKVRVRGRKEICEDFKLV
                     YQANSKEEALDHIDFMTRKWKKQYPRVVNLLLNPALLTFYNFPHAIRRTIYSTNLIEG
                     FNKQLKRYTRRKEQFPNEESLERFFISQFNQYNQKFLGRIHKGFKEIQDTLESMI"
     gene            complement(5313..6632)
                     /locus_tag="ACG804_002562"
     CDS             complement(5313..6632)
                     /locus_tag="ACG804_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFS4833444.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
     gene            complement(6629..7282)
                     /locus_tag="ACG804_002563"
     CDS             complement(6629..7282)
                     /locus_tag="ACG804_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFS4833445.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            7570..>8195
                     /locus_tag="ACG804_002564"
     CDS             7570..>8195
                     /locus_tag="ACG804_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HFS4833446.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQILKVKEKLTILELKRTRFLCYDCGQTFSAKTDLVDE
                     HHQLTKELKQAILIELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMKSVSGSMSFICVDGTTHQLFTILEDRRLYKLTQYFLRFPR"
BASE COUNT         2625 a         1465 c         1001 g         3104 t
ORIGIN      
        1 acgatctctt ctaagtcgga ctcattttcg atcggtttcg cttgataata gtaggtctga
       61 cgagaaatat ttagaatttt gcacatcgct gatatggaat atttatgctt gttggcatca
      121 attacttgtc ttttcgtccg aatatcagcg ccgcttgctt taaaatatca ttctccattt
      181 cgagttgctt atttttcttt cttagtgcga tcaattctgc ttgttctggt gttaagttgt
      241 ctcttttttt gaatgagccc gttgattgtg cttgcttcat ccatttatcg aaagaagaag
      301 gcgtaagctc atactctcga ataatttctg cgcgaggctt accagcgaga tagagatcga
      361 cgatttgttg tttgaattct tttgaatagg ttcttcgttg acgtcttgac atgaaaaatc
      421 ctccagtgtg ttttttatta ttctacacac cttatttttt ctgtctagtc tagtgtagcc
      481 gattcacata aaatggactt tgtctacagt ctgtatcttc tctttttgtg tctactttat
      541 tgacatctat ccaattagta atcaataaat atttcaataa tagtctagct atatataaat
      601 aacattacaa aacctaaaga attatatctg ataaccttcc atgtttttca tatgatgtta
      661 ctctttcaac tttattatta tcatcgacaa aaacaacctt aggtctatga tccttaacct
      721 cattttcatt taattcacaa tatgccatta aaattatttt atctccagtt gatacacatc
      781 tagctgcagc tccattcaag caaatcatcc ctgttcctct ctctccagct attgtataag
      841 tttcaaatct atttccatta ttaacatcaa ctatttgtac tttttcatat tcatatattc
      901 ctgctgcttc taataaattc atatcaacag taatacttcc tacataatct aactcagctt
      961 gttcaactgt agctctatgt atttttcctt ttaacattgt aactttcatt atagccccct
     1021 attgtaattc aaatgtaaaa ttatctatta atcttgtttt tcctataaat actgctattg
     1081 caactaaaac tgatttttca atataattta ctctttgtaa tgataaagaa tcaacaactt
     1141 ctacataatc aatctttgcc aaattataag tatttatatt tttacttatt atctcaatta
     1201 tttttaagct gtctctctct ccattattta aagcttcctt agctaaagtt aaagatttat
     1261 ttaaaatagt agctgaagat ctttcctcta aacttaagta tgtgtttcta gaacttttag
     1321 ctagtccatc ctcttccctt ataattggac accctacaac gtctatatca atattaaggt
     1381 ccctaaccat tcttttaatt acagctaact gttgtgcatc cttttctcca aaataagctc
     1441 tatctgctgg tattatgtta aataatttac ttacaacagt gcaaacccct ctaaaatgta
     1501 ttggcctact agctccacat aaaccttctg ttaatccagt tatattaaca aaagtacttg
     1561 cattgtcaca atacatctct tcaacttcag gattaaatat tgctgttgct ctacctcttg
     1621 tgcatacttc tatatctctt tctaagtctc ttggataact acctaaatct tcatttttcc
     1681 caaactgagt tggatttaca aagatactta caacaacttt atcattttct tttgatgctt
     1741 ttctaattaa actttcatga ccttcatgta aatatcccat agtaggaact aatcctacct
     1801 ttaagccttg ttttttccac tcttttactt gacttctaac atcattcact gttttaaata
     1861 taaccatatt tcttgaccct tttaatataa tttttctaaa acatcatcac ttattttaaa
     1921 cccatgttct ggacctggaa aaactccatc ttttacttcc tctatatatt ttgtaaatgc
     1981 tttattcatc tcttctgata aattagcata tttcttcaca aatttagggg taaaatcact
     2041 atacatcccc aacatatctt gatatacaag aatttgtcca tcacaccctg cacctgctcc
     2101 aataccaatt gtaggtattg atatctcttt agaaattaac tctgcaagct tagttggaac
     2161 acattctaac actacagcga atgctcctgc tttttctaca gctttagcag ctcttattaa
     2221 ttctttagca gcttccttgt cctttccttg taccttaaat cctccaaatg cattaacaga
     2281 ttgaggtgtt aaacctatat gcgccataac aggtatagaa gcctttacta tagcctctat
     2341 tttatcgcat acttctatcc ctccttctaa tttaacaacc tgagctcgtc cttcttttat
     2401 taatcttcct gcattaacta ctgaatcata tactgaagtt tgataagaca taaatggcat
     2461 atctgcaaca actaaagtgt tcttagctcc tcttgtaact gctctagtat gatgaatcat
     2521 gtcttccatt gttactgaaa gtgtatcttc atgtcctaga cataccatac caagagaatc
     2581 tcctactaat attccattta tcccagcttc atcaattatt tttgctgttg aatagtcata
     2641 agctgtaagc attgttaatt tttcatttct taatttagat tctttaaatg taactgctgt
     2701 atttttcatc tatttctctc ctaactctct cctaaatact tttctaattc actataatct
     2761 ctattaatat tttttaacat agctatctct aatacatttt ttgataatag catatataaa
     2821 gctctgtctt catctgataa aacttcacag tgacctttaa ttgttgaaat atcacaacgt
     2881 tcaactggcc ctgtcaaact ttctataatt cctttttctt ttatatttct aatattaaat
     2941 tcaattaatg gatataaagc ttcaattgcc attttttcag taaatccaca ttgaattaga
     3001 tatgtaacgc ttgtattaat aagtcctagc acaaggttac tagatactac tgatgcggca
     3061 tgataaagag atttattctc cttagataca attacagtac tattacctaa ctttttgaag
     3121 aaatcacata aaaactttgc atatttttca tcgccttcaa ttgttataaa agattttttt
     3181 aattttttgt atgaattata tttatctgat attgaaaaca taggatggac agaatagcca
     3241 taagcaccat agtcctgtat atttgaaaag atatctgaag atattgcacc actgcaatgg
     3301 cagattaatt tgtttttgat ttgataattt ttaatttctt gccatacctc ctgaatttga
     3361 ccatcaggag tcgtaatgaa aatagtatca ttttcatcta ctaattctct taagtttaaa
     3421 tattgtttac tagatgtaaa attcgaagct gctaatgacg agtcttcgct tttactataa
     3481 aatcctgtta cttgtatttt atgttcctgg aaatacttcc cgaatgaaca acctaccttg
     3541 ccggctccaa taaaaccaac gttcataatt atcacctcca taaagaagtg agactacaag
     3601 tcccattctt acgatatgag cttaaaaata aaaattaaat caaatataca gtatgttttt
     3661 ttcaaatatc atccatagtt aatttatcat aatatcccat attttaaaat aaaagatagc
     3721 gtaaaatatt ttgtgtaaat agaaatttag ggtagaaaaa aaagtccatt ctgtaaaatt
     3781 aaagttacca cacagaaatt ttataggagg actttctcat gactaaattt actatagaaa
     3841 ttatgcaaac actactcaat aaaggggatt tagatgaatt atttcaggat catttagagc
     3901 gagcgattaa ttcacttcta caagcagagc taactgcttt tttagattac gaaaaatatg
     3961 atcgaaatgg attcaattca ggaaattccc gtaacgggaa ttattcacgt acatttaaaa
     4021 cagaatatgg cgagttgaat ttaactattc ctagagatcg gaatggcgaa ttttctcaac
     4081 aaacactacc agcatataag cgaaccaatg attcattaga aacgaccatt atccaattat
     4141 ttcaaaaagg cattactatg gctgaaatct ccaaattaat tgaaaaaatg tatggtcacc
     4201 actatacgcc acaaacaatc tccaacatga gtaaattggt ggctgaagat gttttagctt
     4261 ttaaagaaag aacgttagaa gccaattatt ccgttatatt tatggatgcg acgcatatcc
     4321 ctgtgaagcg acagactgtt tcgaaggaag cagtgtatat tacgattggt attcgtttgg
     4381 atggaaccaa agaagttctt gggtttacta ttgccccaac tgagtctgct tatatttgga
     4441 aagaagttct tcaagatctt agaaaacgtg ggttagaaga agttttatta gtagtgacag
     4501 acggattaag ctgtattgaa gaaagtatcc atagtgtgta tccgaatgcc caatttcaac
     4561 aatgttgtgt gcatgtatct agaaatatcg ctcataaagt tcgtgttcga ggtcgaaaag
     4621 aaatttgtga ggatttcaaa ttggtttacc aagcgaattc aaaagaagag gcattggatc
     4681 acatcgactt tatgactagg aaatggaaaa agcagtatcc aagagtcgtc aatttactct
     4741 tgaatcctgc cctattaacc ttttataatt tccctcacgc catcagacga acaatttatt
     4801 cgacgaacct gattgaaggc tttaataagc agctaaaacg atatactcga agaaaagaac
     4861 aattccctaa tgaagaatct ctagagagat tcttcatttc tcaatttaat caatataacc
     4921 aaaaattttt aggtagaatt cacaagggat ttaaagaaat tcaggataca ttagagtcga
     4981 tgatttaact gtaattaaca gaatggattt tccatttaca cataattctt gacgctacca
     5041 taatctaaat aaccatcata ttcatctact acttatataa ttgagtttta ttaaactttt
     5101 taagtttcta ttctatcaaa tatttaaaca atctctgcat ccgaaaagac tacctcgtat
     5161 agttttacta acaatatttt tattagcgtg ttcaaatcct gatttcttgt atcaattatt
     5221 ttctgttcac tttcaataag aaaaaagtct ttacttccat ggataataat aagtctctat
     5281 ttttcaataa ctattgcaaa attatatctt aattaagaaa atatttttat tttaaagata
     5341 aaaaattctt catcctgcaa tactttatat tctatattgt aattattcag aatattactt
     5401 acaatatata aacctaatcc attactattt tccttattta aatcaaattt aacatcaaat
     5461 attttatcca tattcgaaat tttattgtta ccgtatgaat tctctatata taaccaatca
     5521 ttaactatcc caatattaat taccccattt acatcagtat attttaccgc attactaatc
     5581 aaattagata gaataatctt taaagctgtt tttcctatat aaacattctc gtctaatata
     5641 taattattga cagttatttt cttttgattt gctaatattt catacttttt taatatgtct
     5701 tctaatgtat catttatttt caaatattct tcatcattat tcaaattttc tatagaatga
     5761 actgataata tttgagaaat attttttgtt aaactatcaa cgatttcaat acattcatta
     5821 atataaatat ctctttcttt atattttcca atattgtatt tcatgttttc cagtattatt
     5881 ttaagactag caagaggggt tttaagttca tgggatgcac ctttaaaaaa gtcatatttt
     5941 aacttttcta attttaaaat ttctttattt ttaaattcca aatcgtcaat tgttcttaat
     6001 aaagtagaat acaaatcatt aatttgttgt tttaattctc caacttcatc attagagcta
     6061 acttttaaac tcattttttt atcaagtttc atcattttat cagtaacaat ttttatttct
     6121 tgtatattat tttttattga ttttgcataa attaaagaaa taatagcaga aaataaaatt
     6181 gatattaata aagaatatgg taaaaattta aggcttaaat ctttcgcatc tttttgcata
     6241 tcagctgtag aaacaaattg tagatttgtt tttttaccat cattaagctt tatttctctt
     6301 tcttcaatta tcaaagaatt actatcactt tctaaattaa catttatatt atctttgatt
     6361 tgtatttcat tcttattatt tttttctttt atgaatactt ttatttcact actcttggaa
     6421 taaaactcca aagtttgttc tatatatttt atttcttttc cattcatatt actagaaatt
     6481 tcatttgcca tattatgaat cttttctttt ctcgtctcca aatatgtttt aggaaagata
     6541 aaaaaaatta atgaatgaac taatataatt attattccaa gaacagaaaa tatttgtatg
     6601 aacatttttg gaaatatctt taattttttc attttctctc caatttatat cctacatttc
     6661 ttatagtagt tatacagtct aattgtaatt tttttctaag ttcttttata tatacatcta
     6721 ttactcgatc ataaggagtt tcttcgctat ctttccatac ataatcaata atttgcattc
     6781 ttgttaacac ttgtccatta ttatccaata aacattttaa tacttctagt tcttttgcat
     6841 ttacatctat ttcttcacca tttattttag ctgtatagct attaaaatta accgatagat
     6901 ccttatattc aaacttctct aaatgtccat aattcttctt aattaaagaa tctattctag
     6961 cttttaagac cggcaatgaa aatggctttt ctacatatcc gtctactaaa ttagtaaatg
     7021 catcaatttt atattcttca tcactaaatg cagtcaagat tagaattggt aaattgcttt
     7081 tctttctaat ttctttcaac acttctaaac catttataaa aggtatctga atgtctaaga
     7141 taaccaaatt tatatcgcta ttaaattttg acaaggcttc tcttccatct ttagcttgaa
     7201 taacagtata tccaaattct gaaagatatt cacttattcc ctctcttatc atattatcat
     7261 cttcaacagt taatattttc atatatacct ccacttaagc ctatacacta gatattatac
     7321 agcatattat ggctctataa tatctagtgt tggtgacacc ttctgttgcc aatacttttt
     7381 cttttttcta ataaatgcaa acagacacct tgaaatcctt tagaataaag ggttctataa
     7441 tattttgtgt tgttggaaaa tcgaaggcga ttttctacta acactttttc ttcgtttcaa
     7501 ctcaaaaaga gactcacttt tggtaaaatt tagtcgacca aaacatcacc ctaccaaagg
     7561 agtcgctcta tggataatca tactagaaaa ttactcggat taacagataa acatttattt
     7621 tttgatgaag aatggctgat tgaaaaagaa tataaaggcg ttcaagcgca gtttattaaa
     7681 gggagattgg atgactcacc ttcccattgt gaacactgtg gatcgattcg tattatccgc
     7741 aacggttcct atacgacacg tactcagata ttgaaagtca aagaaaagtt gactatttta
     7801 gaattaaaac gtacccgttt tctatgctat gattgtgggc agaccttttc tgcgaaaacg
     7861 gacttagttg atgaacatca tcaactaaca aaggaactga agcaggcgat tctcatagaa
     7921 ctgtacgaaa atcaatcacg taaactaatc gctaagaagt acttcgtctc ggatgggacg
     7981 gtgacacgga tcttgcgtga agcaacgaag cattaccagc cacgtatgaa cttccttccg
     8041 acggtgttgt gtatggatga gttcaaatca atgaagtctg tttctggttc catgagtttt
     8101 atttgtgttg atgggacaac ccatcagcta tttacgatcc ttgaagatcg cagactttac
     8161 aaactaactc aatacttcct gcgctttcct agaaa
//
LOCUS       DAZUJR010000107         8127 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.110, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000107 DAZUJR010000000
VERSION     DAZUJR010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8127
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.110"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(338..1036)
                     /locus_tag="ACG804_002565"
                     /pseudo
     CDS             complement(338..1036)
                     /locus_tag="ACG804_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
     gene            1115..1291
                     /locus_tag="ACG804_002566"
                     /pseudo
     CDS             1115..1291
                     /locus_tag="ACG804_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
     gene            complement(1467..2036)
                     /locus_tag="ACG804_002567"
     CDS             complement(1467..2036)
                     /locus_tag="ACG804_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFS4833447.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(2110..2433)
                     /locus_tag="ACG804_002568"
     CDS             complement(2110..2433)
                     /locus_tag="ACG804_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833448.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2587..3399)
                     /locus_tag="ACG804_002569"
     CDS             complement(2587..3399)
                     /locus_tag="ACG804_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833449.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3726..4601
                     /locus_tag="ACG804_002570"
     CDS             3726..4601
                     /locus_tag="ACG804_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010758089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFS4833450.1"
                     /translation="MGKRSTIQLMIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGT
                     FSRVQCTPDLLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLE
                     AMAENHATIDNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDD
                     ELLLLLDKFEKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAI
                     QLGISPRGSLSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKK
                     QIIHTLVAQIPIPVR"
     gene            4615..4938
                     /locus_tag="ACG804_002571"
     CDS             4615..4938
                     /locus_tag="ACG804_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833451.1"
                     /translation="MEKIKDYFINFVLFLVYFIIVLFALVFNNSLGWFLLAFFTLYVS
                     WSLISLSSFLKKLSVTCTLQPLVYRKKSMQVIFSIAKKRTFSLPLPRLQIGFPAIFAE
                     KNKRF"
     gene            4935..5687
                     /locus_tag="ACG804_002572"
     CDS             4935..5687
                     /locus_tag="ACG804_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HFS4833452.1"
                     /translation="MILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFRKSAKR
                     EISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNRIDWKL
                     SAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPELLILG
                     NRAFHGKDPGHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIETLSKD
                     RTVCLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5677..7848
                     /locus_tag="ACG804_002573"
                     /pseudo
     CDS             5677..7848
                     /locus_tag="ACG804_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
BASE COUNT         2430 a         1598 c         1459 g         2640 t
ORIGIN      
        1 ttaacaaaaa tattataata ggatttaagt aagttctaac taatcacata taaaaataaa
       61 aaaacatttg tattttatca aagttttatt atacttgtca atttgtgtac atcctaaaat
      121 ataagctatt tgtttacttc tgtagaatat atactttgtt gttagataag ttgcacatgt
      181 ttatagaatc taaataataa atttttatgt accgcccctc aaagtgaact gaaccccaaa
      241 agttgaacta tttaatggac tgtttccgat attctactgg agatagtcca ttaaatagtt
      301 caacttttgg ggttcagttc aaagaggggg ggatttttta tcgttgtgga atatttaaat
      361 accaacgctt gtcatgaaaa tcttgtgctc cacccttagt atttccttct ggatcgtttg
      421 tcgcacgcat catgacgtat actttcttat tagggaaatc acgcatattg aaagatacat
      481 gatagccaac atttcctaaa gtattataag cttgatttac gtctggtcta taaatcccat
      541 cagctcttac tctagctagt tcttttccag tattgtagtc cataatgaaa atatactcgt
      601 atttataatt agcaatgtgc catccagcta catgcaagtt tgcgttttcg atttctccga
      661 actgatcaat gtgggcgtaa tttgttccat ctgtcagcgt agaatttgca gcacctgctc
      721 gagttggatc aattactggt ttatcctccg aagtagttgg attatcatcc gtaaaaccat
      781 gagccaaatc ataggctagt ttttctttac ttacacccat ttcagaaaga taaccgtaag
      841 gatctgtatg atcgccccaa atattttgtg ttacccataa atgcgatttg attcctggtt
      901 ggttataagg agtgtctaat gttaatggaa taccatattt cattgctgaa tctcttgcca
      961 attcaacgta tactttatag ttcttttcaa aagtttcttt atcatgtgta tgttgtaact
     1021 cgatttgcac aggacttttg gctcacgagg ttgtcctact ctacatcttg ctgatagata
     1081 tgctgaaagg aaaacaccaa cattatgttt tgctttttca gctagaacga gacaagcagg
     1141 aataccttta gaagatatca aaggtttttt aggtcataaa gatgtttcca ctacacaagt
     1201 ctatgcccat atttctcccg aagtgaaaaa aagatcaatg aatcaactag aaaactatat
     1261 agaagagcaa ataaaaaagc actcaaattg agtgcttttt taagctcact atcactaaaa
     1321 ctatcactaa ttttatttat aagcgaacat gtttctatca ctgatttttt aaatctagcg
     1381 aaaaaccctt atcttaaagg cgttcgttca attctttggc aaggtcttca aagcctggct
     1441 tgcctagaag tgcgaacatg gttttcttat agctcatgta gaaaaatttt cttgatgatg
     1501 attttatcca tcaattgaga ttgactgttt tgctctccta tgatttcagc tatgattgtc
     1561 cgattttgcg gttttcttct taactggtag ttgattttcc cagtttccat caactcgcta
     1621 agcatatcca cgactccgcc aaatccggtc tttttcgtaa taaaacctag tgctaccatt
     1681 cgttcatcta gattttttgc tgtaatcgtc acaccagtaa tgagcgagtg ctgtaatgtt
     1741 tgggccagct cttccatccc ttcagcattg gatacgacgg aagctgtttt gttaataggt
     1801 tcttcgttta tttcttttgg ttctttcctc tccactttca ctgtttgacg aaggacatct
     1861 agttcttgca agagcgtttc gtattgttct tgggtcagca tcacgccagc tactttttca
     1921 cgattaaata tatatacgcc agttcccgcg tctcgcgctt gagcaaatac atccatcggc
     1981 gatcgtttca cttctgtgat cgaagatgtg ggaacttcta atttctttaa ttccaatgga
     2041 tttcctcctt tactaatcgc tttttattat agcacagact gacttgtttt gatctttttt
     2101 ccaaaggttt tatcggtttt tgcctaacca gtaattgata tcggtaagaa gtctttcgat
     2161 accaaatgaa ggatggtaca gatacgtttt ttgatcttcg ttatggtcta gtggaaaaaa
     2221 atgatcgatg atcactagat ctgcataccg aggcggctta tttcgagtac atacatgtat
     2281 agagatccgt tttcgatgtc ttagcgtttt gttcagtacc ccagcaagtc ttcttgcttc
     2341 ttggtgttca tagcgaaaaa aaaagacgat tttcacttca ggagggtgga catctaaata
     2401 ccctcgttcc tggagtgttt tcagtaaaag catcccccac tctactgcgg ggtgtgcaag
     2461 tgcttgttgg atcgctagcc gaaattgata tagtttatct ttggaattgg gaaatttttc
     2521 taatgtttcc tgataataac gaacttcttc tatcagccgg tcatggatac caattacgta
     2581 acgaagtcat tcttggtaaa gtacttttgt cagctttgat ttgctttcgc tctcaaattc
     2641 gctattcagc caaaacagcg aatcaagctt ttcagtcaca atcgtcaatt tccgatagtc
     2701 ttgtgtctct tctatccgtt tccaccgctt ttcagtaatc tggttacagc tcaagcgcaa
     2761 aattgctaga taattttttt cttttattgg caaaatctgc tcctctctaa atagcaattc
     2821 aggaaacaat tcaaagaata gtgttcgact gtctcctaaa atctcgattt ctgccggatc
     2881 ctttctttgc ttcaataatt ggatgaacat ctcagaaaag gactgctctc catcatctgc
     2941 aaaaaaatgc ggaaaatctt tcaaaaagca aaacagcaga tatcttactt ttctttctga
     3001 accaaagatc tgtgcttttt tataagaaaa agaaaggtgg tactcgccaa accactttct
     3061 caatcgctct tgcgtagaac gatcgtactt ctgctcgtaa ggttcattca atagcagatt
     3121 tttcagtaaa caaaacgggg gtgattggat cagaaaaaca aacaagagat aaggttcgct
     3181 atatccttga tcataaacta actgaacggt tttcttatga agaatcagct gaatgggaca
     3241 gtcgctttcc gccaaacgtt tcagatgccg atccactgtt ttaacatcga ttttcagttc
     3301 ttcagctaaa tcagcttttc gccagatcaa atctttcatt agattgatta gtgaaaataa
     3361 attctgtgca ttttttgata atagtttttg ccatctcatc gatcatttct cacctgattt
     3421 ctaaacatat tgtttgatca aaatgggttc actcctaaaa agataaaaaa ctccctttct
     3481 atttatttaa atacgcaaat cttcctcatt attttttatt ttactcaatt taatcgtatt
     3541 ctcatttcaa aacgaatgta ctttaaaaaa acataataag atcactttgc ttgtaggatg
     3601 tattcccttc cattacaatg aaataaatag cgattttatg agaaggtgat gtgaaaatgg
     3661 aagaaaaaat agaagaatcc aaacaaaaaa tcgatcagtt gatataagaa ttagaaaaag
     3721 cggtcatcgg caaacgttca actatccaat tgatgatcgt ggccctatta gcaggtggtc
     3781 atgtcttatt cgaagatatt cccggtgtag gtaaaacgtt actggtcaaa gcactagcaa
     3841 aagctgtaca gggaaccttc agcagagtcc aatgtactcc tgatctgctg cctagtgata
     3901 ttcttggttt ttccgtatac aattcacaat caaaagagtt tgaatttcgt ccgggaccga
     3961 tctttaccac gatcttgtta gcagatgaga tcaatcgtac gactcctcgt actcagtcag
     4021 cacttttaga agcaatggcc gagaatcatg caacgatcga caacaataca taccctctag
     4081 acaatcattt ttttgtctta gctacgcaaa atccaatcga gtacgaagga acatatcctt
     4141 tgccggaagc acagctcgat cgttttttat tccgactaca aatcggttat ccttcttttg
     4201 atgacgaact tttgctactt ttggataaat tcgaaaaagt gttggataac ttaaatgaag
     4261 tattgaacag ttatgaaata gaagaaataa aaacaaatgt ggcgaatgtc tttgtcagtc
     4321 ccgaagtggc atcttatgcc ttgcagttag tgtcagcaac aagaagtcat gctgccatcc
     4381 agcttggcat cagtccacga ggaagccttt cctttattca ggcagcaaaa gcttatgctt
     4441 taatccatgg gagaaattac gtcacgccca aagatttgca ggatttagtt ccttacgtgt
     4501 tttcccatcg cctgattttt tacgatcgtt cattgaagga agacgaaaag aaacaaatca
     4561 ttcatactct tgttgcacaa attcctattc ctgtgaggta gattgaggta gacaatggaa
     4621 aaaatcaaag attatttcat taattttgtg ttatttctgg tatatttcat cattgtgctt
     4681 tttgctcttg tattcaacaa ttctttaggc tggttcttgt tggccttttt tactctttat
     4741 gtatcatgga gcttgatttc attaagcagc tttctaaaga aactttcggt tacttgtaca
     4801 ttgcagccac tcgtttatcg caaaaaaagt atgcaggtta ttttttccat agcaaaaaag
     4861 agaacttttt ctttacctct ccctcgttta caaatcggct tcccagcaat ctttgcagaa
     4921 aaaaacaaga gattttgatt cttacaaata aaccgcaaga agtccaattg ctttggcagc
     4981 caaaagaaag aggatgccat gaaacattaa ctgtcatttt tacagcctat gatagtctag
     5041 gacttttcag aaaaagtgca aaaagagaga tctcttttcc tgtgactgtt ctgcctgctt
     5101 tttgtaagat tcaagcagaa aaattacaga gagttctgga aaaaaaacag cagctgaacg
     5161 cgtaccaaag aggtcttgat tttcgggaac atcgcgctta tcgtccaggt gattctttca
     5221 accgaatcga ttggaaattg tctgctcata ctcaagagtg gttataccgt gaatacgatt
     5281 atcaagaaga agaatgttct cctctttttt gcttttgggg ttcgcccagt ccaaaatttg
     5341 aacctctgct agacttgtat ttttctttat ggcatttgag aaaagaaaag cagccggaac
     5401 ttctgatatt aggcaaccgc gcctttcatg gcaaagaccc cggtcatacc tattttgctt
     5461 ctttggaagc tggcgatgag aaagcttttt tcgcacactt gaaaaaatat gcaaaaaaac
     5521 aaatcgtcct ctttgttcct gagaattctc ctgaagtctc agaagctatt gaaacattgt
     5581 caaaagatcg aacggtttgt cttgtttatt tcgtagaaaa acaactcatg gtccaagaaa
     5641 aagacaagat atgttcattg ccaggaggtg aatggattga cgattaaacg ggaaaaatgg
     5701 ctgcgtggcg tttactcctt tgtgatacta agtgtaggtg ctccgatatt tgtagtagct
     5761 aatcaattgc aaaacagcta ccttcttatc ctaactattg gtgtcctatg ccttattgtc
     5821 tgctgtattc ctaaaaaatg ggtacgtttg ctgctttctt tgccagtaat gataggttgt
     5881 ttgtttttat attttccttc gaagacattt tccatattat ggatcttaca gtttttttcg
     5941 tcagtcacag aggaattctt ccatctatcc caaggtaaac tttattattt gccagaaaag
     6001 acagcttttt ttctcataat gttgctgatc tatttattta ttacattgac cgtggattac
     6061 gactattggt acgcaccctt tctttctttg atggcttact tcatgatgct taccgttttt
     6121 cggaaaaaag atttactgta cgaaatgatt gcggtagtaa ctgttttgtt cgtgtatctg
     6181 gcagcaaggc aatttttctc catccggttg ttgtcgggaa acactcgatt ccagtcattg
     6241 actacagttc tgcttatttg tttcttaact tttagcgcta tcttgccttt atatcttccg
     6301 aaagtacacc aatctctcga ggaaacgagt gaaccgatcc gagaatatct taatgatgaa
     6361 gggctttatg acacactcca tgagtatcaa ttaaccggaa gtgcaagaac aggcttcagt
     6421 gagaatgatg aacagcttgg tggaccttta tatgataatg gcgaagttgt ttttacagcg
     6481 aaccaaaaag gaaatggcta ttggaagatc gaaaataaaa atcattacac cggttctgga
     6541 tggatagaag atcaggacgc acccatccaa ccaatccaag aattccctgt tgacatcacg
     6601 agctaccaaa ccgttataga agacaaagaa aacattacat tgaccctaaa aaaacaagtt
     6661 ttcttacctt atccttatgg aaatactacc ttgactgatt tttcattagc tagtggacaa
     6721 acgctttact atttgcctga aagccagcga ttcattcctg tcccgaatga atcgacacgt
     6781 tctgcaactt tacaaacaga aaggttagtt tttacgagag aagaattaaa aagcagtcag
     6841 ttaaaagctg atgatttaga aaatcagcag acaaatcttc aattgccaaa aagtttgcct
     6901 aaacgtattg aggacttggc ggtcgaattg accaaaaatg aagcaacttt aattcgtaaa
     6961 gtcgaagctg tctaacagta tttaaaaaca agcggaaatt tccgctattc caaaacggat
     7021 accgggcata ctccaaaaga acacgattat gtggattatt tcctctttga ttcaaaagtc
     7081 ggctattgtg acaacttttc aacttctatg gtcgtccttc ttcgaacact tggtatccca
     7141 gctcgctgga caaaaggttt tacaaatggg ctcagaacag gcacagataa tcaagggaat
     7201 gaggaataca gcattctcaa tagtcatgct cattcttggc cagaggtata ctttcctgga
     7261 tttggctggc ttccatttga accaacccct tcatttgcca atccaatggg ttcacaacca
     7321 gttgctgaaa caaccgaaac cgtccagcct gctatcgaac aaccaaatga aagcgaaaat
     7381 atggcagaaa ctatttccag tgagagatct gaggtcattc catcagaaga aacaacactc
     7441 acaccagctt ataaaatcgt cttattcagc cttggagtgt gtttatccgt cttgttgttc
     7501 tttctattgt tattcagaaa atctctgcgc tggacaagtt atcttatcta tcttcatttt
     7561 tttgcttcta ctaatacgat tgcatatcaa aaacttctta accctttgga aacattggta
     7621 ccgcgcaaac ccgcagaatc tttgcaggaa tatagcctgc gaatagaaca agaattcaag
     7681 ctagatctgc gtttcattcg attaactact caatatgaag cagaaatata tggacgacaa
     7741 gcagatccgg taaaattcga taaaaaaacc tatttagaaa taacgcatat aataagaaaa
     7801 atggtataca aaaaaattct gacaaaaggg agccgcttca aaaaataaga taaaatttct
     7861 ggagaatcta cttctggaat gccgagaacc agctgattga gtatcgatta atcgagtaga
     7921 ggggaaagcc aactgacctt ccgcccctct cacaccaccg tacgtacgga cccgtatacg
     7981 gcggttcaat aagttgagtg tacgaactgg tacttcaagg agatgtcctc atatccttgg
     8041 cgggccagtt ctttgtctgt taatgatcga tgaagaatat gacttttgga gactgaccaa
     8101 ataccttttc ttgtatttga ccattca
//
LOCUS       DAZUJR010000108         7599 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.112, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000108 DAZUJR010000000
VERSION     DAZUJR010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7599
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.112"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(137..427)
                     /locus_tag="ACG804_002574"
     CDS             complement(137..427)
                     /locus_tag="ACG804_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833453.1"
                     /translation="MGEKKIKGAGILLVMSKALFLLPCTFMFIVLCYFKRRKKWCWID
                     VLLFLPFFPLIYFLEEIWDDMACDSAFLFSHSLGLMISLTIFAIVLFFLNKK"
     gene            complement(545..805)
                     /locus_tag="ACG804_002575"
     CDS             complement(545..805)
                     /locus_tag="ACG804_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833454.1"
                     /translation="MGVDHLIVLSKLLFWIPFIIMTSAFFYLFKRPNKYLLLSACPMI
                     YFIHKIRGFYYYDSGISLFCYEIGLLASAIFFIFVLEYFRKK"
     gene            complement(942..1355)
                     /locus_tag="ACG804_002576"
     CDS             complement(942..1355)
                     /locus_tag="ACG804_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HFS4833455.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1811..2296)
                     /locus_tag="ACG804_002577"
     CDS             complement(1811..2296)
                     /locus_tag="ACG804_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833456.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2435..2650)
                     /locus_tag="ACG804_002578"
     CDS             complement(2435..2650)
                     /locus_tag="ACG804_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HFS4833457.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2874..3674
                     /locus_tag="ACG804_002579"
     CDS             2874..3674
                     /locus_tag="ACG804_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFS4833458.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3693..5561
                     /locus_tag="ACG804_002580"
     CDS             3693..5561
                     /locus_tag="ACG804_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFS4833459.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5554..6045
                     /locus_tag="ACG804_002581"
     CDS             5554..6045
                     /locus_tag="ACG804_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HFS4833460.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6033..6587
                     /locus_tag="ACG804_002582"
     CDS             6033..6587
                     /locus_tag="ACG804_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HFS4833461.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6605..>7599
                     /locus_tag="ACG804_002583"
     CDS             6605..>7599
                     /locus_tag="ACG804_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HFS4833462.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2707 a         1213 c         1443 g         2236 t
ORIGIN      
        1 ttgttactat gaataacata ataagaaagt aaagtggatt gatttgagat ctttttatac
       61 ttcaaaaaag ataacaccca actttcaaaa atatgttttg gaagttggga caaacgagtt
      121 aatacatttt aatacattat tttttattca aaaaaaatag cacaatggca aagatcgtaa
      181 gagagatcat aagccccaat gaatgactaa aaagaaaagc agaatcacat gccatatcat
      241 cccatatttc ttcaagaaaa taaataagcg ggaaaaaggg aaggaatagt agaacatcga
      301 tccagcacca tttttttctt cttttgaaat aacataaaac aataaacatg aacgtgcagg
      361 gaagtaaaaa caaagcttta ctcataacta acaaaatacc agctcctttt atttttttct
      421 cccccacatt caaagagtaa caatggtatg tacttaataa tagaaaaatg gatcaacttg
      481 tatgaataac agctgaaaag atctgcacca aataaaaaac ttccagccaa aactgactgg
      541 aagtttattt ttttctgaaa tattctaaca caaatatgaa aaagatggcc gaagctaata
      601 agccgatttc gtagcaaaac aatgagatac cagagtcgta ataataaaat cctctaatct
      661 tatggataaa atagatcatc ggacaagcag ataagagtaa gtatttgtta ggccttttga
      721 ataagtaaaa gaaagcactg gtcattatga taaatggtat ccaaaacaaa agtttactta
      781 agacaatcaa atgatcaact cccatatttt ttaccaagag agatcataac atctttatcg
      841 taaaaacaaa atattttttt gctcattttg aaaatttaaa catactcgtt cttatccaaa
      901 tatataaaaa tcgcccctca ttcatcgaga ggcgataagt tctaatttaa ctcaattttt
      961 tttgtttctt ttggctgata agctgtttta ggtaatacca atttcagcac accgttttta
     1021 aaggttccag tgattttttc ttcatcaaca ttaggaagat agaatgaacg tttgtaagag
     1081 accgaatgtc tttctttccg tacatagttg ccatcttctt tatcttctgt atgggactca
     1141 tgattggcgg agatcgtcaa agtattatct gaatattcaa ctgtcgtgtc ttctttgtca
     1201 cagccaggca tatcagcagt tagtttgtat tctttttcat tttcgactaa atctactttt
     1261 ggataacttg aaacacctaa aaaatcattg aatgctggac taaacacgtc attgaaatca
     1321 gggaacatgt cgcgaatgct aggtacattt gccatttttg atcatccttt caataagtat
     1381 tttttattta tccctattta cgtaataact ctattttgaa aaaaatgcaa gtataatggt
     1441 tagctttgtg aatatttcat ctaatacgat acaaaggcta tctttctaat ttgaaaaagg
     1501 gatcattaaa ataataagaa gaaaatatgt caaaaggtaa aaaagtaaat tcttctatcc
     1561 aaatatagaa aaattgaatc tagaaaaccg cccgacaata aatttcatta actcagttga
     1621 ccgaaaatga agtagatacc aaaaatttat caagagagca agtagagaag tgagtatatt
     1681 cataagagaa atagctgtaa cgaattatta ggttaatgca aatgcttatt tatactccgt
     1741 ataactttct cagaaaaaat gataccaata atgacttgct agtactgtaa atccgtataa
     1801 tatcatctaa tcaaaatggt gttccatttg catctgtcat cgtaatcgat ccttcgggtg
     1861 acactcgata aaaaccaacg cttccagatc ctccttggga acggatttgt ttgctggaag
     1921 ctgtgaacaa ataatctcga tcaatttttt gataaaagct aataacaata tcgtcacttt
     1981 gtaattcgga acggtgggca ataagaaata gaagtgcttt gtcagagttt tctaatggaa
     2041 gagaaggtac agtgctttct tgcatttcag atgttgaaga aatgctaaac gactgaatac
     2101 ttgattggct atgttgcgaa tctacattac cagtagaagt attagtaatg gaagtagtag
     2161 aagtactttt agttgaacca acctcagttg ttgaaatggc tgctgaagat tctttaacag
     2221 aattctttgt tttatatcca caggcagaaa aaagtattac agttcccaac aagcctgcgt
     2281 aaatcccttt atgcatgata gctcctccta aaatagatta tctttattca gtatatcact
     2341 taaacaaaga aaagcagatg gtttaaaatg aaaaaacctt cccaataaag ggaaggttca
     2401 tgaagataat aactttttta ataattatag ctttctaata tctttcatca acttttctag
     2461 taatcattgg gaaaaatttc aagcagtaga tcgcacaaat acctacgacg atataaatga
     2521 tcttcgcaaa aatagttgtt gaaccaccag caatcatagc tactaaatca agttcgaaca
     2581 agcctaccaa cagccagttc aaccctccca caatcaataa agttaatgca atagcatcta
     2641 aagttttcat tagaattctc ctttcttaaa tgataaaaca attatatatc aaaaagagaa
     2701 acattgctta tataacgctc aggaatttta gcaatctatg caaaaagatg aaaatttttt
     2761 ttgctcttcc attagtacac attttttagc tgaagctgta aatttcatgt cttaattttt
     2821 tttagtgagc ttttatactg gatttgtaag aaaaaagaag gagaggatca catatgtcgg
     2881 attggttgga tattgcagga aaagtagtaa ttgtaactgg aggttcctca ggaattggaa
     2941 gaagtatcgt cgaaaatttg ttgaagcaga atgcacaagt agcgaatttt gatgtaactg
     3001 aatgccgtat acagcatgaa aacctactat ctttaaaagt cgatgtgtct tctaaaacgg
     3061 acatagaaga agggatatat aaagtaatga aacatttcaa gacgatcgat ggtctagtca
     3121 ataatgcagg aataaatatt ccttctcttc taatagatag aaatcatcca aaaagcaagt
     3181 atgaattatc agaacaagtt tttgataaga tgatcgctgt caatcaaaaa agtgtatatt
     3241 tgatgagcca agcagttgga agaatcttgg tgcaaaaggg atcaggagtg atcgtgaatc
     3301 tttcttctga atcaggattg gaaggatcag aaggacagag ctgttatgct gctacaaaag
     3361 cagcgatgaa cagttttact cgttcttggg caaaagagtt aggaaagagg aatgttcgtg
     3421 tggtaggtgt tgcaccaggg atactggaag aaaccggttt gagaacacaa gaatatgaag
     3481 aagctctttc ttatacgaga ggtataagcg tcgaacagct gagaaacggt tacagtcgaa
     3541 caagtacgat ccctctagga aggagtggta agctgcaaga agtggcggat ctagtctgct
     3601 attatctttc agaaagatca agttatatca ctggagtcac gactaatatt tcaggaggta
     3661 aaacaagagg ataaaggata ggggggacgc acgtgacgct agtaaacaga tggtaccaat
     3721 tattgaaatt actagtcact cacaagaaag tttcaatcca ggaagtgcaa aaagaaatca
     3781 aaaccagtaa tcaaaccata aaaaaagata ttggggagtt gaatgaagaa attgccggta
     3841 ttgcaaaaat catccaaaaa aacaaacatt ttgaacttga aatttatgat tttgattttt
     3901 ttgatgagat catgcaagga aaattgaaaa cagccagtga tttcaattcg gcatccaaaa
     3961 gaatcgctta tttactaaat aggctgatcg aaacagagga tttcttacgt atggatgatt
     4021 tgtctgaaga agtcggtgtc agcagaggaa cagtggtcaa ggatctaaag acattaaaag
     4081 agatgatcaa tgattttgat gtaaagatta caggcacacc aaataaagga ctaagaataa
     4141 taggagatga gctagaatta cgactacttt tattttattt tgtttctccc tacttttcag
     4201 agacgaaaac agaacagttt ctagaagaaa aacaagcaat caaacatttt cagaagaaga
     4261 cgaatgctag taaacaagaa atcacccttt taacgaaagt tatcggtatt tctttgaata
     4321 gaatctctag taactatctg ttgaagaagc ccatcaatcg ttacagtggg tgttttgaat
     4381 atatccaaga attcaatgaa ctgatcaatc agttggaaga aatctatgaa ctaactttga
     4441 gccaatatga aaaagatttt atcagttttc ctttgaacat catcaacaca agtataacga
     4501 tgataaggaa agctaactct gatttgcgct tatatttcga ccccatgatg atgcgtattc
     4561 gacgattaga tctcattgat ctggatgagt ccttcttata tcaagagatg aaacagcacc
     4621 tctctttatt gataaatcgg gtaatttttc gttatcgatt gactgattta ttttatggtg
     4681 agatagaaaa aaagtatcct ttttcttacc aaatcgctag cgaatgcata caagcattag
     4741 aagctatctt gcaacataag atctctaaag tagagatcag ctacctaacg ttgtatttgg
     4801 agttagcatt tcgatatcaa aaagagcatt tttcctctaa aaaagtagcc attgttcata
     4861 cgacaggaaa aggaacagca ttaatgatcc aaagacaaat caaaaggata ttggggaggg
     4921 atatacaaat aacacatgtt tcagaagaac aatatgaaaa agtagatcta aacaaatatt
     4981 tcgctgtttt tacaacgatt ccgttaaaaa atgtaaatga agagacaccg gtgatccatt
     5041 tgactaatct ttttgatgac tcttggttaa gggcacaatg gcaaaaagca aaaaaaaagc
     5101 gattagccgg gtttcattct actgtttttt tctatcaaat atggaaagaa aaaaagacgt
     5161 atcaagaata tttaaacaaa ttagtcgctc ctttgatcag aggctattat gtggatgaag
     5221 aatttgaaaa aaggatcttg aaaagagaat atcagcaaag cacatttgtt aacaaagaat
     5281 ttgcttttcc tcacacaacc aaccagctat ctcaacacat tgttttatca gtagggctaa
     5341 taactgatca aggtttagca gaaacaggag gaaatggagt tattttttta tttgccatac
     5401 ctgaagaaat gacggctgaa gttgagaatg aattatttga gctatacgat atcctatttg
     5461 aactcataaa aatgggaata gatgagttta ttgaattagc accgacacaa gaatcatttt
     5521 taaaactaat caaaagtaaa ggagagagac ttcatgaatg atatgtatct attcatagtt
     5581 ttcgcagctt cagcttatgt gctgcaagca gttatcagtt ggaagcaact aaagcatttc
     5641 aatcaaacat atagcgaact gcgaagaaaa ggaaaagtag cgattggtaa acgacctggg
     5701 aaaatccgtt caggcacgat tgttatgcta gctatagacg atcatgatca agttttagaa
     5761 gtcagaaaaa tgcaaggggt tacatctttg gcaaaatttc attcattacc tgtctatgcg
     5821 ggtgaagata tccattacat cgatcgttac catccctcag ttcgagcgga agatcgtttg
     5881 acacaagcag ctttagaaaa tgccagagaa gtatacttac gaatagaggc aggaaatgaa
     5941 aaaagtgaac aaccttcatt gccttttatt gctatgctca ataattttcg gatatggaaa
     6001 agtacgatca aagaaaaaag gagtgacaaa cgatggatat cataacaaaa tttgctgagg
     6061 gatttatgag gctgttccaa acaggtgcag aaacattcat aagctggatg acaggaatcg
     6121 taccagttgt cttgatgctg atggttgcaa tgaatacgct gattgctttt ttaggtgaag
     6181 accgagtaac gaaagtagcc aaattatcag cgaaaaatcc gcttactcgt taccttgtgt
     6241 taccgttctt atctgctttt atgttgggaa atcctatgtc atttacaatg gctcgtttcc
     6301 ttccagaata ctacaaacca agctattatg ctgctcaagc tcaattttgt catacgagca
     6361 atggtgtatt cccccatatt aatcctggag aattgtttgt atggatgggg attgctcaag
     6421 ggatcgaaac cttagggcta aattcgatgg agctggctat ccgatacttg cttgtgggac
     6481 tgctgatgaa ctttattggt ggttggataa ctgattttac tactggattt gtatgcagac
     6541 agcaaggaat cgttcttagc aaaaaagtag agctttcagt tgattagaga aaggagagtt
     6601 ttaaatgtat ggtgatatta agatcgtaag aggaaacggc gggtatggag gtcctttgat
     6661 tattaggccg acaaaagata aacacaagtt catctatgtc acaggtggag gtgagaggcc
     6721 aatgatcgta gataaaatag aagaactgac aggtatggag tctatcaatg ggttcaaaac
     6781 atcaatacct gatagtgaaa tcgcgcttgc aatcgttgac tgtggaggga ctcttagatg
     6841 tggaatttat cctaaaaaag ggataccaac catcaatatc gtttccacag gaaaaagtgg
     6901 cccattagca caatatatca ctgaagatat ttatgtttca gcagtagggt tagaacaaat
     6961 acagccacta atggaaactg atgataacaa agaaacagta aatactgcat ctccagataa
     7021 aaagtacaaa tatgatactt ctaaaaagat aaccgagcaa aaagcagagc agcaaaactg
     7081 gatagcaaaa attggaatgg gcgcgggaaa agtagttgct acattcaatc aatcagcaag
     7141 agaagcagta gatacgatga tccggacagt gatccctttt atggctttcg tttccctttt
     7201 gattggtgtg atacaaggtt ctgggatcgg taatgtattt gctaacatta tggcaccttt
     7261 agcaggaaat gcagttggat taacaatcat tggctttatt tgttcactgc catttttatc
     7321 tcctttgctt ggtccagggg cagttattag ccaagtgatt ggaacattga tcggtgtaga
     7381 gattgggaaa ggaaatattc ctccccaatt agcattaccg gcactatttg ctatcaatac
     7441 tcaaaatgca tgtgatttta ttccagtcgg tctaggtttg gaagaagcaa aagctgagac
     7501 agtagaagta ggtgtaccat cagttcttta ttcaagattt cttaacggca tcccacgagt
     7561 tatcattgct tgggtagcaa gttttggatt atatagctg
//
LOCUS       DAZUJR010000109         7429 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.113, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000109 DAZUJR010000000
VERSION     DAZUJR010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7429
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.113"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            452..721
                     /gene="rpsN"
                     /locus_tag="ACG804_002584"
     CDS             452..721
                     /gene="rpsN"
                     /locus_tag="ACG804_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFS4833463.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            736..915
                     /gene="rpmF"
                     /locus_tag="ACG804_002585"
     CDS             736..915
                     /gene="rpmF"
                     /locus_tag="ACG804_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HFS4833464.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            947..1324
                     /locus_tag="ACG804_002586"
     CDS             947..1324
                     /locus_tag="ACG804_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833465.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            1345..1494
                     /gene="rpmG"
                     /locus_tag="ACG804_002587"
     CDS             1345..1494
                     /gene="rpmG"
                     /locus_tag="ACG804_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFS4833466.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            1518..2501
                     /locus_tag="ACG804_002588"
     CDS             1518..2501
                     /locus_tag="ACG804_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFS4833467.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVIADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLEKFNHPLVFESDSSENH
                     YNGKHYHQHHQEHEFKSILLTSDQDIKKDFLFQLIDRLILTNQGSLYRFKGLIALQDQ
                     DFIVAIQGVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            2531..2653
                     /locus_tag="ACG804_002589"
     CDS             2531..2653
                     /locus_tag="ACG804_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HFS4833468.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKQNKMKKLA"
     gene            2671..4194
                     /locus_tag="ACG804_002590"
     CDS             2671..4194
                     /locus_tag="ACG804_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HFS4833469.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLIQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKLNKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNEMHNWPTFYPASLSEHEIAQEMMAH"
     gene            4218..4457
                     /locus_tag="ACG804_002591"
     CDS             4218..4457
                     /locus_tag="ACG804_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4833470.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYQFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(4650..5213)
                     /locus_tag="ACG804_002592"
     CDS             complement(4650..5213)
                     /locus_tag="ACG804_002592"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFS4833471.1"
                     /translation="MDFSISFITIYRAICNDLFDTEPLSHGNKGLIRSLHHRGKTRHT
                     KNHVESRGKICLTHSIHGHPKSADDRSDFGHWKADIVAGKTSGTCLVTLTDRKSCFLL
                     AGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITPDRGKEFSNHFAVTEVLNNMPFYFP
                     DPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(5306..5524)
                     /locus_tag="ACG804_002593"
     CDS             complement(5306..5524)
                     /locus_tag="ACG804_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4833472.1"
                     /translation="MSQYCHLTILKRERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTNHLPKRKKIMLIEEKNADVITF"
     gene            5713..6660
                     /locus_tag="ACG804_002594"
     CDS             5713..6660
                     /locus_tag="ACG804_002594"
                     /inference="COORDINATES: protein motif:HMM:NF014542.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFS4833473.1"
                     /translation="MYGDHGKEIAVIVNDIGEVNVDGVLVDKKGFKRTGEKLVSMPNG
                     CICCTLREDLIVELDQLVQFSDLNQIVIEASGISKPIPIIQAIILAKNPLDIDLTQRL
                     EIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVVEEEQDIRGLLIDQFECCNILLLNN
                     SDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVDLSKILNTNLFNIDETSYSMGWFKE
                     LELGYQNHIPETEEYGISSFIYRNRLLLDAQKFAHLTDKNFPGNITRAKGFLWFAQHS
                     DFSTIFETSGSHKSIESLNYWVASLPKIECQMIIQKNPN"
     gene            6627..6716
                     /locus_tag="ACG804_002595"
                     /pseudo
     CDS             6627..6716
                     /locus_tag="ACG804_002595"
                     /inference="COORDINATES: protein motif:HMM:NF019303.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            6849..7256
                     /locus_tag="ACG804_002596"
     CDS             6849..7256
                     /locus_tag="ACG804_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HFS4833474.1"
                     /translation="MKFLRKAGVKIGDVIIIGILIIPSFIPLFVFSIEKENETTEDAI
                     KYAIVQIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVR
                     TGWISKPGQTSICLPHKLVISIEKKESKDYYIY"
BASE COUNT         2634 a         1100 c         1449 g         2246 t
ORIGIN      
        1 attaaacagc atctaatttt gaatacacga aagaatcagt atgattgaat tagttcactt
       61 aatgtctatt cttataatat aaggaataat caaagtttta aaaaattggc gataaaccag
      121 ttaaacataa aagattgaat aaaaagttat agtttctttc atattgccgt tttaagtaga
      181 ggaaaagcta cttaaaacgg tatttgtgtt tgattggact aataaaagtg aattcttatt
      241 tttcagagct taaactgcat attcttttaa atgatttgat tatctctatg taccgataaa
      301 ttcgttttca aatagttatc tattcatatg agttttattt catgttattt attgttgaca
      361 agagcaactc ttgttggtaa agtatcagtg tcaaaacgta acgattacga tttgagatgt
      421 ctaaatcaaa ataaaaggag tataaaggta tatggcaaaa aagtcgaaaa ttgctaaagc
      481 aaagaaacaa atggcgatga ttgaaaagta cgcagataaa cgtcaggaat taaaagccgc
      541 aggagatcgc accgctctcg ctaaattgcc aagagattca aatccgaatc gtctgaggct
      601 tcgtgatcag acggatggtc gtccaagagg gtatatgcga aagttcggta tgtcccgtat
      661 taagtttaga gaacttgccc atcaagggtt gattcctgga gtaaaaaaag caagttggta
      721 aaaggaggaa atatcatggc agtaccagca agaaaaacat ctaaggcgaa gaaacggtta
      781 agaagaactc atcaaactgt agtaaaacca gaaatttcat ttgacgaagc gaatggtgat
      841 tatagacgta gccatcatgt atctttaaaa gggtactata atggaaagaa agtaattaaa
      901 ggagcttcaa aatagtttaa tatataactt ttaggaggga atcaaaatgg aaattattta
      961 cccaccttta gttgaagaag gattaaagta ttatcttgaa acgacccagc aatcgctaga
     1021 taaatgcact ttttatcgtt cgatggtaga gagaggaatt attactgaaa cgggtttacc
     1081 gacccaacag gcaattgaaa atggattagt caaagattac tatgaggacc aaggcttatc
     1141 atttgatgat tttttaagaa tctatccaat ttttgaagag tatgacgagg agttatttca
     1201 atgtattgat ggttattggg agatacctgt tgatatgaaa gaaaatttag tttcacaatt
     1261 ggaatctggc gagttaactt ttgaagatgc acaacaaatt caagcatatc ttgaagatcg
     1321 ataagtattg aaggaggaag atttatgcgt caaaatatta ttttggaatg tgtcgaaact
     1381 ggagaacgtc tgtatctcac cagcaaaaat aaacggaata accctgaacg gttagaatta
     1441 aaaaagtatt cgccaaaatt gcgcagacgg gcaattttca aagaagtgaa atagctaagt
     1501 ggtaaaaagg tgacaaaatg ggcataccag ttacaatcgt ttctgggttt ttaggggctg
     1561 gaaaaacaac gctaatcaat caagccttgc aagtctcacc ctaccccagg gaagaaatta
     1621 ttataattga aaatgagttt ggtgaagttg ggattgatca caaattatta gttcatagcg
     1681 aggaacgggt gttacaacta aataatggat gtatgtgttg cagtcttcgc agtgatttat
     1741 tagcaatatt gatttcttta ctggaaacaa tagaagaaca tcaacaacca atttcacaaa
     1801 tcatcattga aactacaggt atagcagatc cccaaccaat cattcaaaca cttttaacag
     1861 cgcctcaact aagaggaaga gtatatatcg atagtttatt gactgttatt gatagtgaca
     1921 gttttgaact tattgaaaga gaaccacaag cccttaagca acttgtcata gcagatcgca
     1981 tttttgtgtc tagaaaacaa aacttgaatt tatctgcact aaaaaaatta cagagagaaa
     2041 tcaaaagtat taacccttta tccgatattc gaatgttcac acatagtgaa acgattcaaa
     2101 aaaaggattt ttataatttg gaaaaattca atcatccctt agtttttgaa agtgattcat
     2161 cagaaaatca ctataatggc aaacactatc atcaacatca tcaagaacat gagtttaaat
     2221 caattctctt aacttcagat caagacataa aaaaagattt tttattccaa ttaattgacc
     2281 ggctgatttt aaccaaccaa gggagcctgt atcgttttaa aggattgatt gctttgcaag
     2341 atcaagattt tatagttgcc atacaagggg taaacgaaca ggttaatttt caatacacca
     2401 ctcgacaaaa agaccaaacc actattattc taattggaaa aatgttggat gaagaaagga
     2461 tcaaacagag ttttgataaa ttactggcgg aaagcaaata atgataagta ttgattaggg
     2521 gtaatttcta atggagaaaa cggatatatc tagtgcatat cgacgactta aaagcccgaa
     2581 tatcaaaact agaaaaaggg cattaaaaat tatcaaagaa cataaacaaa ataaaatgaa
     2641 gaaattagca taattaagga aggaaaaaga atgaagaaaa tcagtgtagg acttattggg
     2701 atagcagctc taggattatt gggagcttgc tccagcacta atgatgcaaa agtatcgaat
     2761 gataaagatg gaaaattaga aattgtaaca acattctatc caatgtatga tttcaccaaa
     2821 aacatcgtcg gcgatgaagc gaacgtggat ttaatggttc cagcgggatc agaacctcat
     2881 gactatgagc cctcagctaa ggatatggca aaagctcatg atgctgatgt ttttgtatat
     2941 cataacgaaa acatggaatc atgggtacca aaagctaaag aaagttggaa gaaagctggg
     3001 cctaatgtag tagaaggaac aaaagacatg attttattgc caggtagtga agaagaagat
     3061 catgatcacg gagaagaaga tcaccatcat gaactagatc ctcatacgtg ggtttcaccc
     3121 aaaatggcaa ttaaggaagt ttcaaatatc aaggatcagt tagttaaatt gtatccgaaa
     3181 aaagcaaaag tatttgagac aaatgctgaa aagtatttga ctaaactgaa acggttggat
     3241 gctgactata ccactagtct taaagaagcg aaacaaaaaa gttttgtgac acaacatgca
     3301 gcctttggat atttagcttt ggattatgga ttgatacaag ttcctattgc tggactaagt
     3361 cctgaagaag agccatcttc tggtcgatta gctgaattaa aagagtatgt taaaaaaaat
     3421 aagatcaatt atatttactt tgaaaagaat gctaatgata aaatcgcaaa aactttggcc
     3481 aatgaagctg ggataaaatt ggaagtattg aatcctcttg aaagtcttac aaaagaacaa
     3541 atggataatg gtgaagatta tgtttcagta atggaagaca atctaaaagc gttagagaaa
     3601 acaactatgg ttgctggtga agaggtagtt ccagaaaaag aagcgaagga tgaaaagaca
     3661 gttgctaatg ggtactttaa agatgccgat gtgaaggatc gcgaattgag tgattataca
     3721 ggcgaatggc aatctgttta tccgttgtta aaagatggaa ttttggatga agttttcgat
     3781 tacaaagcaa aactcaataa agacatgaca gctgccgagt acaaagatta ttatactact
     3841 ggctataaga cagatattga tactatcaac attaaagaca acaccattga ttttgtagtc
     3901 aacggtgaac atcatcaata cacatacaaa tatgttggat acaaaatttt gaattatgaa
     3961 aaaggaaacc gtggtgttcg ttttaatttt gaaactgatg atgcaggtgc tggtcgtttt
     4021 aaatatattc aatttagcga tcatggaatt gcaccaagta aggcagagca tttccatatt
     4081 ttctttggtg gagaaagtca agaaaaactt tataatgaaa tgcataattg gcctactttc
     4141 tatccagctt cattatctga gcatgagatt gctcaagaaa tgatggccca ttaaaatcca
     4201 atctttggag gaaatacatg gtaagaaaag tattattgtc tatggattcc aagaatattg
     4261 atgcttatcg gcgttatcaa tttgcaaagc aaatgagatt aaatgggagt acattagctg
     4321 atattgctgc aactttacat gttagtattg acacagttca tagagtatta aaacgggatc
     4381 ctgattgttg ttttatcaag gtcaatactg gaagaagtag acgtttagca aaacggcata
     4441 atagcttggc caattaattg ataataccag agtagatcat ttttccctta tttggatttg
     4501 atctgctttt tattatttct tgaattgtca aatcaagcgc aacactttat caaagaagac
     4561 ttcataaggt gttctccaat ctaaacactt tctaggtctg ttattcagtt tttcaatcat
     4621 ctgatttatc gttgagttat ctaccgtagc tatctctttc gattttggca agtattctcg
     4681 aatgagtcta ttcgtatttt aatttgttca ttgttgccaa gggcatgagg atctggaaaa
     4741 taaaagggca tattattcaa tacttctgta actgcgaaat gattggagaa ttcttttcct
     4801 ctatctggag tgatcgtttt gaccgcctca tttggaatac tgcttaaaag ttcaatcatt
     4861 ttctcgctca cataagcggc tttctttctg gggaccttct ttcctgctaa aaggaagcat
     4921 gattttctgt ctgtcaaagt cactaaacaa gtaccactag ttttgccagc tacaatatcg
     4981 gctttccaat gaccaaaatc acttctatca tctgcggatt ttggatggcc atggatcgaa
     5041 tgagtaaggc aaatcttccc acgagactcg acatgatttt ttgtatgtct tgtttttcct
     5101 cgatggtgca atgaacggat caggccttta ttgccgtgtg agaggggttc tgtatcgaaa
     5161 agatcattgc aaattgcacg gtagatcgtg ataaaactaa ttgaaaagtc catatgttca
     5221 tgcttcaaac gattcgagat tttctctggc gaccactgaa aatcgacaaa taaatgacga
     5281 acaattgacc aaactcacgg atcatttaga atgtgataac gtccgcattt ttttcttcga
     5341 taagcataat ttttttccgc tttggaaggt gattagtttt tttcttgttt cttctcagtt
     5401 catgtaaaat agtaaacggg ctatgctgaa tgtcgttgcc aattatacta atagaaaatc
     5461 cttcttcgtg aagcagaaag attctttctc gtttgagtat agtaagatga caatactggc
     5521 tcataattat tttccttcta ggagtgttct cgacaaactt atactagttg gatatcgatt
     5581 atgactcatt tttatgtgtt gcacttaaag tgtaaattca aggtatagaa agaggttccc
     5641 tatgaaaaaa tacctattac aatcttaact ggctatcttg gttcaggaaa aacgatactt
     5701 ctaaatcata ttctgtacgg tgatcacgga aaggaaattg ctgtcattgt aaatgacata
     5761 ggggaagtaa atgttgatgg ggtattagtc gacaagaaag gttttaaaag aactggagaa
     5821 aaacttgttt cgatgccgaa tggatgcatt tgttgtacat tacgcgaaga tttgattgtt
     5881 gaactagatc aattagtgca attttctgac ttgaatcaaa ttgttattga agcttcagga
     5941 atcagcaaac caattccaat tattcaagca attatattag ctaaaaaccc tttagacatt
     6001 gatttgaccc aacgattaga gattggtgcc attattatag tagtggatgt aaaacgtttt
     6061 tgggataatt tcgaaacggg tgaaaagatt caggaaagaa aagctgaagg taatgtagtt
     6121 gaagaagaac aggatattcg tggcttgtta attgatcaat tcgagtgttg taacatatta
     6181 cttttaaata atagtgactt agtgtcaacc aagacgattt acaaaattaa cggtctaatt
     6241 gctaagttac agtccaatgc caaaataatt aggacaatta aaggtgaagt agacttatcg
     6301 aaaattctaa atacaaatct ttttaatata gatgagactt cctattcaat gggctggttc
     6361 aaagagttag agcttggcta tcaaaatcat attcctgaaa cagaagaata tggtatctca
     6421 agttttatct atcgaaatcg gttactcctt gacgcacaaa aatttgccca tcttacggat
     6481 aaaaattttc ctggcaatat tacaagagca aaagggtttc tttggtttgc ccaacatagt
     6541 gatttttcga cgatctttga aacatcgggt agccataaaa gtattgaatc attaaattat
     6601 tgggtagcta gtttacctaa aattgagtgt caaatgatta tacaaaaaaa cccgaattga
     6661 aggaagcctg gcatccgttg tttggtgaac gcattaataa actagttttt attggtatga
     6721 agatggatca acaatgtatt aaggaacaac ttgagggttg tttaactgat tctcttaatg
     6781 cagataattt ccgaaaaatt tcaccatttc catggaaaaa ttctaatatg tttagccaga
     6841 tatcgttaat gaaattttta agaaaagctg gtgtcaagat aggcgatgtc ataattattg
     6901 gcattttgat tattccctct tttattccct tatttgtatt ctctatagaa aaggagaatg
     6961 aaacaactga agatgctatc aaatatgcca tcgttcaaat tgatggcaag gaaatggatc
     7021 gcttcgattt ggataagatc aatcataaac tcgtgaatta tcatcctgcg aagggacaat
     7081 ataatattgt tgagattaaa gatggaagaa ttcgagttaa agaagataat agtcctgatc
     7141 aaatcgcggt tagaactgga tggatctcaa aacccggtca aacgagtatt tgtttacccc
     7201 ataagttagt tattagtatt gagaaaaaag aaagcaaaga ttactacatt tactaatctg
     7261 gaaatagatg aggaggtttt taataagaaa aagatattat tattaataat agcaggggct
     7321 ttattaagtg tgttaagcgc ttgtggacaa gaaaaagaag cggtgacaac aggcacaagt
     7381 atctttaacg ggacctgcaa tggtttagtt aacagtcggt tagattact
//
LOCUS       DAZUJR010000110         7397 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.114, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000110 DAZUJR010000000
VERSION     DAZUJR010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7397
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.114"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..2357)
                     /gene="pglX"
                     /locus_tag="ACG804_002597"
     CDS             complement(<1..2357)
                     /gene="pglX"
                     /locus_tag="ACG804_002597"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system adenine-specific
                     DNA-methyltransferase PglX"
                     /protein_id="HFS4833475.1"
                     /translation="MDKKAIKNFAVNARRKLIDEVMTKAKRLGIDESKIEDVKKIDSN
                     LQEIEKSGIRIQGKEIAQRNKLIAELKQRASVTSYSEAFQELIEEVAYTWFNRLIAIR
                     FMEVNDYLPDTYRVLSSEISGKIEPDIITDIYDADIFEELSSNEQQQVRTWKTDNSAE
                     AMDKLYQLIFIKICNQLNDYLPELFEEVEDYTELLFTASYIKKDGVIADLLSIPEDDF
                     YVQAGGQVEIIGWLYQYYNSEPHNQVVNIYKGIVKKQDIPAATQLFTTDWVVRYMVDN
                     SLGKYWLDHYPNSELRNKLKYLIPDKYAFEQATSVSNLKPEELKIIDNAMGSGHILVY
                     AFDVLMEIYLTLGYSERDAARAIVEYNLYGLEIDKRAYQLSYFAIMMKGRQYDRLFLK
                     KSLSPNLREFIDSPKVTDEYQERISELNNDKYSERWNEYKELIFDQFENGKELGSIIK
                     LVDKNNQAITKEYLGKVREYISKFNEFTNMDILYGMKEIQEKYLHILDVAEMLVDKYV
                     AVVTNPPYLNKMDKKLKKYVNDNYSDVKKDLFSVFIKLNSQMLIDNGYASFMTPFVWM
                     FISSYEKLRSFLINERNISSLIQMEYSAFEEATVPICTFTIKNSNEQDGSYIKLSDFK
                     GGMEVQKIKTLEAIHQHGECDYFYSTNQDNFKKIPGMPIAYWASDNVITDFAQGKLTN
                     DVADAKQGLATGNNNKFLRYWFEVEFNKIKFDAKTLEDAKKSRKKWFPTTKGGRFRKW
                     YGNNEYVVNWENDGDEIKNYVNENGKLKSRPQNLNYYFKKGITWST"
     gene            complement(2421..6092)
                     /gene="brxC"
                     /locus_tag="ACG804_002598"
     CDS             complement(2421..6092)
                     /gene="brxC"
                     /locus_tag="ACG804_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX system P-loop protein BrxC"
                     /protein_id="HFS4833476.1"
                     /translation="MLIKDIFAKPIDRNIQGVIKVGQAKDENVQQELEEYVVTKELQK
                     HFKTIFDAYQRSINTPTDKMGVWIQGFFGSGKSHFLKIISYLLANREINDKKAIDYFK
                     EDGKIKDPLTLATMERCSQINTDVILFNIDSKSDAGGKKDKNGIVNVFLKVFNEMQGL
                     STIPHLADFERRLIKEEKFDAFKAAFEEINGAKWQEERHEFDWIQDDIKEAALKIDFM
                     SEAAIDNFLEKASGNYLISIDDFANLVKSYLDSKEADHHIAFLVDEVGQYIGGNRELT
                     LQLQTVVEDLGRICEGKAWVLVTSQEAIDHVTNFDNNSDNDFSKIKDRFATTVSLSSA
                     NADEVIKERILKKKEFANDSLALQFETVQTELKNKLLFVDSPELKLFQDAENYAEVYP
                     FIPYQFNLLGQILTEIRNHSYQGSNLSSGERSLLAMFKEAAERNKENDTTSLVSLDQF
                     YYSLERWIDTAISRVITQATNNSHIQRPTDIDNFNVNVLRILFMIKYVDQAIKPNVEN
                     ITSLMIRNINEDRLETKKRVEEALDLLIKENFVRKNLDSYIFQTDEEQEITREIKNQN
                     ITDSDLIVELSKRIFDGVLDRNSFAYEKLGMSGGNKFKNRYTFTYAQVLDQRPYKQAG
                     NAEMTVNFISPYSDLAGQEAELALKSSRNLLFVELPSDKEFKDDIAMYARMNLYLTTT
                     YSSVVKNFDAIRSEKSGELQELSASINDQLNELLKSAKFFYNGAEIQLTGSDFKAKFQ
                     SALQKMAEEVYHKLNQIDAPKEKEDILYLVKESKNEIIEDPSNEQAVQEIFNFINDQK
                     RNHLTITMKTIRDRFETKQPYGFTELDVEWCIAKLFMSGKIDLLYNNVQISRMDDPNS
                     IVMIIQKRRESEKIKIEPSAVISPKAKKLVDEIGRELFQSRNIVDENNNEHTMENFKK
                     YLKGQLDNLRSYFDLQNTYTYPSAYEYEQIKKYLEVIVQTSDVEDFFYTIKKYRDELF
                     DWAETYDKIKNFHKQNSTQKKIWENAQDKIRLIEKSRRQTSSQEIDQLIHEMKTILKK
                     ADPYSDMMKLNELIQEFIEQYNQLLELESQEILNKLTEEKQATFKLLEGKDFKDQFVP
                     IVDQEFQELKAKIEQANTIDDLVFLSLNVAEQYLIFNQRFDNEENRRRQEEQARKQIE
                     AANLIRETEKDEIDSAAKAEEIAIVKPTIQQKTVPMRTLNVHVKTIKSAADIDELTAE
                     INQKLKEQLQENTEITIQF"
     gene            complement(6117..6692)
                     /locus_tag="ACG804_002599"
     CDS             complement(6117..6692)
                     /locus_tag="ACG804_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1788 domain-containing protein"
                     /protein_id="HFS4833477.1"
                     /translation="MSLSIQEHLEKLNEVIQKEDFLLNRGLGNEVGYYIFDYDPKDEL
                     IVRDYINDISGTSVGDNYEVKVYNLYVIMLEYLEKRGFTEKAIKMEERRGLQKLVESI
                     GRLLKMDLPEEENVFFEYVDAHTPEKSVVFLTGIGELYPLIRAHSILNKMHQVFDRVP
                     VVMMYPGEYDELSLTILNTNKDDNYYRAFRI"
     gene            complement(6692..7291)
                     /locus_tag="ACG804_002600"
     CDS             complement(6692..7291)
                     /locus_tag="ACG804_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1819 family protein"
                     /protein_id="HFS4833478.1"
                     /translation="MNKKYSAGLVSKRFWFSEFKLYIQLRLEGYTDIEIKEKNEHENI
                     FFAVSSNRQKEIYQNVKRRVSQLDEAGLQLFNQLNIDNQKLVNLISILMIDDLFNEFM
                     TEVYAENLRKGNLQLTPVDYRSFFTEKRRSSEDISKWKDYTIKRLIAAYQTNLIETGL
                     VRGEKEYGRMTPILLDKRLIQWLVDKNRKDIVLALGGIL"
BASE COUNT         2183 a         1399 c          976 g         2839 t
ORIGIN      
        1 gtcgaccaag taattccctt tttaaaatag taattaagat tttgtggtct agattttaac
       61 ttcccatttt cattaacata attttttatt tcatctccat cattctccca gttaaccacg
      121 tattcattgt ttccatacca ttttctaaaa cgaccacctt tagttgtagg aaaccatttt
      181 tttctagact ttttagcgtc ctctaatgtt ttagcatcaa actttatttt gttaaattct
      241 acttcaaacc aataccgcaa aaatttattg ttatttccgg ttgccaaccc ttgttttgca
      301 tctgcaacat cgttagttaa ttttccttga gcaaaatcag tgattacgtt atcgcttgcc
      361 cagtaagcaa tcggcattcc tgggattttt ttgaagttgt cttgattagt actataaaaa
      421 taatcgcatt caccatgctg atgaattgct tctaacgttt taattttttg aacttccatt
      481 ccacctttaa aatctgataa ttttatatag cttccatctt gttcatttga attttttatc
      541 gtaaacgtac aaattggaac ggttgcttct tcaaaagctg aatactccat ttgaatcaaa
      601 ctagaaatgt ttctttcatt aattaaaaat gagcgtaact tttcatagct agaaatgaac
      661 atccaaacaa atggcgtcat aaaggaagca tatccattat caatcagcat ttggctattc
      721 aatttaataa acacagaaaa tagatctttt ttgacatcag aatagttatc atttacatat
      781 ttttttaatt tcttatccat tttattaaga taaggcggat tagtgactac cgctacatat
      841 ttatcaacta gcatttcagc cacgtcaaga atgtgcaagt atttttcttg tatttccttc
      901 atcccataaa gaatatccat attcgtaaat tcgttgaatt ttgatatata ctctcttact
      961 tttcctaagt attctttagt tattgcctga ttatttttat cgactaactt aatgattgat
     1021 ccaagttctt tcccattttc aaattgatca aaaattaact ctttgtattc attccagcgt
     1081 tcactatact tatcattgtt caattcacta atacgctctt gatactcgtc tgtcacttta
     1141 ggagaatcaa taaactctct taaattcggc gatagacttt ttttcaaaaa aagacgatcg
     1201 tattgacgcc ctttcatcat aattgcaaaa taagacaatt gatacgctct tttatcgatt
     1261 tcaagaccat ataaattgta ttcaacgatt gcacgtgcag catcacgctc agaatatcct
     1321 aacgtaagat aaatttccat caatacatcg aaggcgtaaa ctaaaatatg cccagacccc
     1381 attgcgttat cgataatttt tagttcttct ggttttaaat tacttacaga tgttgcttgt
     1441 tcaaaagcat atttatctgg aattaagtat ttcaacttat ttcttaattc actattggga
     1501 taatgatcta accaatactt tcctaaacta ttgtcaacca tataacgaac gacccaatct
     1561 gtggtaaata gttgagttgc tgccggaata tcttgttttt tgacaatccc tttataaata
     1621 ttcaccactt gattatgtgg ctcactatta tagtactgat acaaccaccc aataatctct
     1681 acctgtccac cagcttgaac atagaaatca tcctctggaa tacttaaaag atcagcgatt
     1741 acaccatctt ttttaatata agaagctgta aacaaaagtt ctgtataatc ttctacttct
     1801 tcaaatagct caggtaagta atcattcaat tgattacaga tttttataaa aatcaattga
     1861 tacagcttgt ccattgcttc tgctgaatta tctgttttcc aagttctgac ttgttgctgt
     1921 tcattactag ataattcttc aaagatatcg gcatcataaa tatctgtaat aatatctggc
     1981 tcaattttcc cacttatttc actagataat acacgatacg tgtcaggtaa ataatcattt
     2041 acctccataa accgaatggc aatcaatcgg ttaaaccacg tataagcaac ctcttcgatt
     2101 aactcttgaa aagcttctga ataagaagtg acagaagcac gttgttttag ttctgcaatc
     2161 aatttgtttc tttgcgctat ttcttttcct tgaattctta ttcctgattt ttcgatttct
     2221 tgtaaattgc tatcaatttt cttcacatct tcaatttttg attcatcaat tcctaaacgt
     2281 tttgctttag tcattacttc atcaattaat tttctacggg cattgaccgc gaaattcttt
     2341 atcgctttct tatccatttt tctttccctt ctatatgtaa cctttgaaaa gacaggcacc
     2401 tttttatgcc tgtcttttca ctagaattga atcgtgattt ctgtattttc ttgaagttgt
     2461 tccttcagtt tttgattaat ttcagctgtt aactcatcaa tatctgctgc tgacttaata
     2521 gttttaacat gaacgttaag tgttctcatt ggtactgttt tctgttgaat agtaggtttt
     2581 actatcgcta tttcttcagc ttttgctgca gagtctattt catctttttc agtttcacga
     2641 atcaagtttg ctgcttcaat ttgtttacgt gcttgttctt cttgacgtct gcggttttct
     2701 tcattatcga aacgttgatt aaagatcaaa tactgttctg ctacgtttaa tgataagaaa
     2761 acaagatcat ctatagtatt cgcttgttca atttttgctt tcagttcttg aaattcttgg
     2821 tcaactattg gtacaaattg atccttaaaa tcttttcctt ctaataattt aaatgttgct
     2881 tgtttttctt ccgttaattt atttaatatt tcctgacttt ccaactctaa cagttgatta
     2941 tattgttcaa taaattcttg aatcaactca tttagtttca tcatatctga ataaggatca
     3001 gcctttttca aaatggtttt catctcatga atcaattgat caatttcttg gctagaagtt
     3061 tgacgccgac ttttttcgat taatctaatt ttatcttgtg cattctccca gatttttttc
     3121 tgagtactat tttgcttgtg gaaattttta attttatcat atgtttcagc ccagtcgaat
     3181 aattcatcgc gatatttttt gattgtataa aaaaagtctt caacatctga cgtttgaaca
     3241 attacttcaa gatatttttt tatttgctca tattcataag cactagggta ggtataagtg
     3301 ttttgtaaat caaaataaga gcgtaaattg tctaattgac cttttaaata tttcttgaaa
     3361 ttttccattg tatgttcatt gttattttca tcaacaatat tacgactttg aaacagttct
     3421 ctaccgattt cgtcaaccaa tttttttgct tttggcgaaa tcaccgcgct tggttcaatt
     3481 tttatctttt cactttctcg tcgtttttga ataatcatta caatactatt tggatcatcc
     3541 atccgtgaaa tttgtacatt gttataaagt aaatcaattt taccagacat gaaaagttta
     3601 gcgatgcacc attccacatc aagttctgtg aatccatacg gttgttttgt ttcaaaacga
     3661 tcacgaattg ttttcatcgt aatcgttagg tgatttctct tttgatcatt gataaaattg
     3721 aaaatttcct gaactgcttg ctcatttgat ggatcttcaa taatttcatt tttgctttct
     3781 ttcactaaat ataagatatc ttctttttct ttaggcgcat caatttggtt taatttatgg
     3841 tatacttctt cagccatttt ctgaagtgct gattggaatt ttgctttaaa gtcggagcct
     3901 gtcagttgaa tttctgcacc gttatagaaa aattttgcag atttcaacag ttcatttaat
     3961 tgatcgttga tacttgcact tagttcctgt aattcaccag atttttccga acgaatcgcg
     4021 tcaaagttct ttactacact cgaataagtc gttgttaaat aaagattcat tctagcatac
     4081 attgctatat catctttaaa ttctttatct gatggcaatt ctacgaataa taagttacgg
     4141 gaactcttaa gcgcaagttc tgcctcttga cctgctaaat cagagtatgg tgaaataaaa
     4201 ttaactgtca tttcagcatt tccagcttgc ttgtatggac gttgatctaa cacttgtgca
     4261 taagtaaacg tataccggtt tttaaattta tttccacctg acatgcctaa tttttcatag
     4321 gcaaaactat ttcggtctag aacgccgtca aaaattcgtt tagatagttc tacgatcaaa
     4381 tcactatctg taatattttg atttttaatc tcacgagtaa tttcctgttc ttcatcagtt
     4441 tggaaaatat aactatctaa gttcttccgc acaaagtttt ccttaattaa aaggtccaat
     4501 gcttcttcta ctcgtttttt agtttccagg cggtcttcgt tgatatttct tatcatcaag
     4561 ctcgtaatat tttcaacatt tggtttgatg gcttgatcaa catatttaat catgaataaa
     4621 attcgtaaga catttacgtt aaagttatct atatcagttg gtctttgaat atgagaatta
     4681 tttgtagctt gtgtaatcac tcggctaatt gctgtatcaa tccaacgttc taacgagtaa
     4741 taaaactgat ctaaagaaac caaactggtt gtatcatttt ccttatttcg ttcagcggct
     4801 tctttaaaca ttgctagtaa tgaacgttca ccagacgata agtttgatcc ttgatagctg
     4861 tgattacgaa tctcggttag aatttgcccc aataaattga attgataggg aataaatgga
     4921 taaacttctg cgtaattttc agcatcttgg aagagcttta attcaggact atcaacaaag
     4981 agtaatttat ttttcaattc tgtttgaaca gtttcaaatt gtaaggctaa agaatcattg
     5041 gcaaactctt ttttcttcaa aatacgttct ttaattactt catcggcatt tgctgaagat
     5101 aaactcacag ttgtggcaaa acgatccttg atcttagaaa aatcattatc agaattgtta
     5161 tcaaagtttg ttacgtgatc aatcgcttcc tgacttgtca ctaataccca agccttacct
     5221 tcacaaattc gacccaaatc ttccacaacg gtttgtaact gcaaagtcaa ctcacgatta
     5281 ccgccgatat attgtccgac ctcatcgact agaaaggcaa tatgatggtc tgcttctttg
     5341 gaatcaagat agcttttaac tagatttgca aagtcatcaa tgcttattaa ataatttcct
     5401 gatgcttttt ctaaaaaatt atcaatagcg gcttcactca taaaatcgat tttaagtgcc
     5461 gcttctttga tatcatcttg gatccaatca aactcatggc gctcttcttg ccattttgcc
     5521 ccattaatct cttcaaaagc agctttgaat gcatcaaact tttcttcttt aattaaccga
     5581 cgttcaaaat ctgctagatg tggaatcgtg cttaatcctt gcatttcgtt aaataccttt
     5641 aaaaaaacat tcacgattcc gtttttgtct tttttaccac ctgcatcact ttttgaatca
     5701 atattaaaca gaataacatc tgtatttatt tgtgagcacc gttccatcgt tgccaaagtc
     5761 agtggatctt tgattttccc atcttctttg aagtaatcaa tggctttctt gtcatttatt
     5821 tctcgatttg cgagcaagta agaaataatt tttaagaaat gagatttacc tgaaccaaag
     5881 aacccctgaa tccaaacacc cattttatct gttggtgtat tgatactccg ttggtaggca
     5941 tcaaaaattg ttttaaagtg tttttgtagt tctttcgtaa ccacgtattc ttctaattct
     6001 tgttgaacat tttcatcctt tgcttgaccg accttaataa ctccttgaat atttcggtca
     6061 attggttttg caaaaatatc tttaattagc atttaatctc ctaccttcca tcccaactaa
     6121 attctaaatg ctcgataata attatcatct ttattggtat taagaattgt caaacttaat
     6181 tcatcatatt cccctggata catcatcaca actggtacgc gatcaaatac ctgatgcatt
     6241 ttatttaaaa tagagtgcgc tctaattaat ggatataatt cgccaattcc tgtcaggaac
     6301 acaactgatt tttctggtgt atgggcatcc acatattcaa aaaatacatt ttcttcctca
     6361 ggtaaatcca ttttcaataa acgaccaatg ctttccacta atttttgtaa accacgtcgt
     6421 tcttccatct taatcgcttt ttcagtgaaa ccgcgttttt ctagatactc taacataatc
     6481 acatagagat tataaacttt cacttcataa ttatcaccaa cagatgttcc agatatatca
     6541 ttaatataat ctcttacaat taactcgtct ttcggatcgt agtcaaagat ataatagcct
     6601 acttcattac ctaaaccacg attcaataaa aaatcttctt tttgaattac ttcattcaac
     6661 ttttccaaat gctcttgaat cgataatgac attataaaat tcctcccagt gctagtacaa
     6721 tatctttacg attcttgtca actaaccatt gaatcaatcg tttatctaat aatatcggag
     6781 tcattcgtcc atattctttt tcccctctga ctaatcctgt ttcaattaga ttcgtttgat
     6841 aagcggcaat aagccgttta atcgtataat ctttccattt tgaaatatct tctgaacttc
     6901 tccgcttctc tgtaaaaaaa gaacggtaat caactggtgt taattgcaaa tttcctttac
     6961 gtagattttc agcatatacc tcagtcataa attcattaaa aagatcatca atcataagga
     7021 tggaaatcaa attcactaac ttttgattat ctatatttaa ctgattgaaa agttgcaatc
     7081 cagcttcatc cagttgacta actctccttt tcacgttctg atagatttct ttttgacggt
     7141 tactgctcac tgcaaaaaaa atattttcat gttcattttt ctctttaatt tctatatctg
     7201 tatatccttc tagtcgtaat tgaatatata acttgaactc tgaaaaccaa aagcgtttag
     7261 aaactagacc agcagaatat tttttattca atagattgcc tcctaatcat ctataattca
     7321 ataagtaaac aagtgttttt tgctcatcgt tagcattcat tttttagtat ctactataca
     7381 atacatattt attatag
//
LOCUS       DAZUJR010000111         7249 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.115, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000111 DAZUJR010000000
VERSION     DAZUJR010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7249)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7249)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7249
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.115"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(38..1464)
                     /locus_tag="ACG804_002601"
                     /pseudo
     CDS             complement(38..1464)
                     /locus_tag="ACG804_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612187.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            1707..2162
                     /gene="tnpA"
                     /locus_tag="ACG804_002602"
     CDS             1707..2162
                     /gene="tnpA"
                     /locus_tag="ACG804_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HFS4833479.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            2427..2525
                     /locus_tag="ACG804_002603"
                     /pseudo
     CDS             2427..2525
                     /locus_tag="ACG804_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558064.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2748..2978)
                     /locus_tag="ACG804_002604"
     CDS             complement(2748..2978)
                     /locus_tag="ACG804_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HFS4833480.1"
                     /translation="MDEAMDHPLLNKFIKDLILQIFSMIDEQEPTESKRHRAQGIIKI
                     AKRMFSIKGVLSYTVLIQKIPNHLVYKNNVED"
     gene            complement(3208..4026)
                     /locus_tag="ACG804_002605"
     CDS             complement(3208..4026)
                     /locus_tag="ACG804_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFS4833481.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            4187..4876
                     /locus_tag="ACG804_002606"
     CDS             4187..4876
                     /locus_tag="ACG804_002606"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HFS4833482.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4890..6392
                     /locus_tag="ACG804_002607"
     CDS             4890..6392
                     /locus_tag="ACG804_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFS4833483.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            6405..6881
                     /locus_tag="ACG804_002608"
     CDS             6405..6881
                     /locus_tag="ACG804_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFS4833484.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(6978..7088)
                     /locus_tag="ACG804_002609"
                     /pseudo
     CDS             complement(6978..7088)
                     /locus_tag="ACG804_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2343 a         1149 c         1308 g         2449 t
ORIGIN      
        1 aaatccactc cttttttcat gctctaaaat gatattttta cacaactgtt acggttgttt
       61 tacgaaattg gacgggactt tgccagttta atttctgttt tatccgttca ttattgtagt
      121 aatagatata gctatcgatg gctgatttta attcctcgaa acagttataa actttcccgt
      181 gaaaaatctc ttgttttaat aagccaaaaa aattctccat aagtgaatta tctaagcagt
      241 tccctttccg agacatgctt tgaaagattt tgtactcctt caatttgttt ctataagctt
      301 tcatttgata cgcccaacct tgatctgagt gaaacgtacg acgataggga caatcgttag
      361 tggtctggat agcttcctcc aaaccttcca ttaccgctaa tgcattgggc ttttcagaga
      421 tacgatagga taaaatctca ctattgaaca tatccataaa aggatctaga tacaatttct
      481 tttgacggat aatgcctttg gcatccactt catggtattt aaattcagtt gtatccgtcg
      541 tgattttctg atggcagata ctggtgtaga aacgacgatg gatccgattt ttggctactg
      601 ctccgacttg tcctcgataa gaattgtagc gccgtgattt acgtgtgtat gtcgttactt
      661 ttattcctag cttcttgatc aggcgctgaa ctttcttttt attgatagag aaaccgcggt
      721 ttcttagttc attggtcatc cgtaaacagc cataatcctt gtgcttctcc cgaactttaa
      781 gcatttccgc ttcaatctct tgatctggat ttttacggtc caatcgtttt tgccagtaca
      841 taaagattgc cttagggaac tttaaagttt ctagaagctc aactaattta aacggtcctc
      901 ggaggcttgc gatgattcgt gcgattgctt cattcgtcgt tgttgggctt cctgttttcg
      961 cagcttcctc aattctttta aaaaggcatt ttcaatttga agggaacgga ctcgtttctc
     1021 caactcctcg atgcgttcac gttctttaga cgttgcttta gttgtagatt ttttcttatt
     1081 tttgggttca tttttcttag acaagatagg tggacatcct ttcgtttttg agagtccatc
     1141 gatcccaccc tcacggaatt gacgcatcca actagcgatc aaattagggt tgttcatgtt
     1201 aagtgtgttg gcaacttcac gataggacag ctcacttgtt agatataact ctatcgcatc
     1261 cagcttaaat tgaacagaat attttttctt ttgtcgcttt cttactagac cctcttcacc
     1321 aaattcttga taggcattga tccagcgctt cacttgtgat ggagccttaa tggaatattt
     1381 ctttgccaga taatcacttc cgcctttacc atccaagtaa tcatgaacga tctttaattt
     1441 aagttcaaaa gtatacttag ccataaaaaa taccgacctc caaaagttag attttttggt
     1501 ctaacttttg ggggtcggta caaaacttaa aagttttaga cccttttatt ttcttaatga
     1561 cttcagtcag ttttgtgcgt aaagcgtgcg aaacaagaaa accgcgcgtt tctacgcgtg
     1621 gaagaagtat ctttagcgat aaaaactcct ttcgatatac tagtgagtgg ctaccaaccg
     1681 ctcatcagat cgaaaggagt tttttcatgt caaatgacga taaaagttta gcatatactc
     1741 gttggaattg taagtatcat attattttta caccaaaata tcaacgaaaa gtaatctatg
     1801 ggcaattacg aaaagatctt ggaaaaatac ttaggaagtt gtgcgaaatg aaagatgtgg
     1861 aaatcataga agcacatgca atgctagatc atattcacat gcttgttcga gtaccaccaa
     1921 aaatatgtat atccagtttt atggggtatc tgaaaggtcg tagtgcggta ctaatccacg
     1981 agcagcacgc aaatctcaaa tataaatacg gaaacaaatc cttttggtcg aagagatact
     2041 atgtgagtac agtcggattg aatcaaaaga caaatgaaaa atacatccgt gaacaagaag
     2101 ctgatgatcg cattcgatat attataagta aaagagagta cgtagaacca tttaaaaaat
     2161 aaagagaagt aagtgagtga agatgagcag ttggcggtct tttaaaaatc cccttttaag
     2221 gggcagcgag tgtcgacccc ttctaggggg attaaaaata cacccgtcct cacgggtgta
     2281 tgggttactg atagacttga ttttaactgg tgtcagaaac ttatgtccag aaagggtgat
     2341 gaaattttgg caatttacgg ctattcaaga attagcacaa gcaaccaaga ttacaaaaca
     2401 caaattcaaa cattagaaaa tgctggcgca gaaataatct tcctagaaaa tcactggatt
     2461 atcgaacacc tttggaagta tttttgagtt acgtaagtat tgatgatctg tctaacttaa
     2521 tttgacaatt aagagtatat ttacttcaga tggtaaggca acaaaataaa atacaatagg
     2581 cagatgaact aataaataaa atctgtatta aatacagata aattaatata aaaatcaaaa
     2641 ggatcataaa cttttaacaa gtgatgaaat gggtggaaat tgattcttat agacagtttg
     2701 tctcataaca ttgaagtatt ttgcaatttt agcattgaaa cactttttta atcttcaacg
     2761 ttgttcttat aaacaagatg attgggaatc ttttgaatta acactgtata gcttagaaca
     2821 ccctttatag aaaacattcg cttagcaatc ttaataattc cttgtgcccg atgtcgttta
     2881 gattcagtag gttcctgctc atcgatcatg gaaaaaattt gaaggatcag atccttaata
     2941 aatttattta agagaggatg atccattgct tcatccatac tcgataaact agtgataatg
     3001 agctacacgt ttttctttca agttgatcaa tagcttccac gataaaaata tctttagata
     3061 aaatcaagaa ccgtaggaac tacagggata tttggtcaat aagagccacc gctattagta
     3121 aaaaataagc tatcaagtat gctctcatcc caagaattgc ctacttcaat cgttaaaaac
     3181 cgttaggttt agctaagtgg gggtagttca ctcaatactt ttatcaataa tagagcgcaa
     3241 aactttttct cttaattcaa ctgaatcaat attattgttt tgttcataac catgaactaa
     3301 tagatcacaa atataaagtt gtgatatttt tccagctaaa gatccaccat taagaaattc
     3361 ttcaatggct gtttgtaaaa ctaagtctgc agactttcct ataggtgaat gaatatagtt
     3421 agttatagca ataatttttg cgccattttt tttagctatt ttcaatgaat cataagtatc
     3481 tttcgttttc ccagataaag aaaaaatgat tactaaatca ttaactgtta ataaagaagc
     3541 gacttgggct tgaaaatgag ggtctagtac agcttttgct tgaactccta cgcgaagaaa
     3601 catattttct aaatcaagac tagtatttcc actagatccc actccaaata tatatatgtt
     3661 ttttgattga gtgatcattt taatggcttc attcaatttt tcttcgtcta aaagcctaat
     3721 agtggaatag agagcttctg ttaaactatt agcaatttca tcatagtact ttacactagt
     3781 cggatgttct tttttttgac taaagtcttc ctttgcaatt tcaattttta aatcagaaaa
     3841 accagaaaaa ccaatttttt gacaaaagcg aataatagta gcatcgccaa cttttgtgtt
     3901 tttcttaata tcactcatcg tactataaat aatagttttc ccagaattta aaataaaatc
     3961 agcgactttt ttttcagact tcgttaaaaa tggataattt tctttaatta aatagatata
     4021 actcatacaa actcctctac aatttcaact tttctccatt atactccaaa ataataaaaa
     4081 aaactcctaa atactccatt tttatcttta cttttatgaa agcggatgct atattgtttt
     4141 tggagttatt atccaaaaat aataaaaaat tggagcgttt aggataatgg ataaaaagag
     4201 gtttttagat cttatttcaa aaggtttgat tgtttcatgt caagcattac ctggtgaacc
     4261 attttacaaa gaggaagaaa gtttaatgcc ttattttgct ttggctgctc aaagggctgg
     4321 agcagttggt atacgtgcaa attctgttcg agatattatt gaaattagaa agtgtgtatc
     4381 attaccaatg attggaatta ttaaaagaga ttatccacca gaatctccat tcattactgc
     4441 cactatgaga gaagtagatg aattagtaga aaccggtgtt gaggtaatcg ctcttgattg
     4501 cactcttaga aatcgacatg atggactatc tataaattct tttattacta aaataaaaga
     4561 aaaatatcct catcagttat ttatggcaga tatttctaca tttgaagaag gcaaaaatgc
     4621 atataaagca ggaatagatt ttgtaggaac tactttaagt ggatatactg aggaaagtaa
     4681 aaaacaagat gggccagata tagatttgat taaaaaattg gtagaagaag ggatttgtgt
     4741 aattgctgag ggaaggattc atactccaga acaagcaaaa gagataaaaa aaataggagt
     4801 tgcaggtatt gttgtgggtg gtgctattac tcgaccacag gaaattgcat caagatttgt
     4861 taaagcatta agttaggggg agaaataaaa tgtttaaaaa attttcacaa ttaggacgcg
     4921 ctttcatgtt accaattgct atattaccag tagccggatt actattggga ctgggaggag
     4981 cgttaacaaa tgagagtgct ataaatgctt atccattttt agatcaaccg tggttgcata
     5041 caattttaag tattatgagt tatgctggaa atgcagtttt tgcaaaccta gcactaattt
     5101 ttgcaattgg tattgctgta ggacttgcaa atggagataa aggaacagct ggtttagctg
     5161 gtggagtagc ttatctagta tatactgcaa ctattagtgg gtttcttgaa cttttttcag
     5221 caaaagatgc aacactagat acaggtgtag tgggatcaat tgttgttggt ggtactgttg
     5281 catttttaca caatcgttat agaaaaattg aattaccaca attcttaggt ttttttggag
     5341 gatcaagatt tattccgatt gtttctagtt tagctgcaat cattattggt tctttctttt
     5401 atttaatttg gccaccaatt caaaatggtt tagtagttgc tggtgaacaa attgcccaaa
     5461 tgggtagttt aggaactttt ttatatggtt ttttattgcg tttaacaggt gctgttggac
     5521 tacaccacac catttaccct ttgttctggt atacatcttt aggtggtacc gaaactgtag
     5581 ctggatcaac aattgctgga gcccaaaata ttttctttgc ccaactagct gatccaaacc
     5641 acactggtct gtttacttat ggtactagat tttttgcagg aagatttgca acaatgatgt
     5701 ttggattacc agcagcatgt tatgcaatgt atcgtgcaat tcctaagaaa aatcgtaaaa
     5761 agaatggtgg gctttatttt agcggggccc ttacatcatt tttaactgga attactgaac
     5821 cagttgaata tatgttttta tttgttgctc cttggcttta tgtgattcat gcattcttag
     5881 atggattatc tttttatttt gctgatatct taaatattcg tgtagggaat tccttttcag
     5941 gtggtttgat cgacttttta ttattcggtg tacttcaagg gaatgacaaa actaattggt
     6001 taaaattaat tccttttggt attgcatggg catttatata tttctttgtt tttacattct
     6061 ttatcaaaaa atttaaggta gctattcctg gaatggaaga agaatcagaa gttcattctg
     6121 aaaaagtaat aaacaaaaat acatcattac atgaagagtc tcttatcatt attgaagctc
     6181 ttggtggaaa agaaaatatt gagtctgttg aagcttgtgc aactcgtttg cgtgttgctg
     6241 ttacgaatgg ggagattatt caaaaacaaa caataaaaga cactggtgca actgctgtct
     6301 tcgaagtgaa gggtggcatc caagctgttt ttggagggaa agctgactta ttaagtcaag
     6361 aaatcaatca aatattagga aaagataatt aggaggtttt taatatgttt gaaattttca
     6421 aaaagaaaaa acaagaaact ttttatgcac cttgttccgg aaaaatcatt tccatcacag
     6481 aagtaaatga tcctgtcttt tcacaaaaat tactaggtga tggttttgcc gtcatacctg
     6541 atggttcaaa aatttatgct ccattggctg gtcgagtaac aaatatattt cctactaaac
     6601 atgctattaa tataaaaagc aactcaggca ttgattattt gattcatatt ggaattgata
     6661 cagttgaatt acaaggagag cctttttcga tttgtgttca agaaaatgat gaggttactc
     6721 ctgaaacctc gttggttgat gtggattttg acaaaataat aaaatctggt aaagatactt
     6781 ctgttatagt tgtttttccg gagaaaaatc agttcaatga tttaataata gataatggtc
     6841 gaattgctca tgggaattca tgtggaaaaa tcacttttta aaaaagtgta tataaaaagc
     6901 tataaaataa gctaaatagg atatttgtca aatgaagttg gtgaacagaa agaactgttt
     6961 tctttctgtt cattttttta ttttattagt aatgattccc catgccaaat catgatccgt
     7021 aatttaaagt tataaaagct tcgaaatcca ttggcatttc gttggaatac cttgatatga
     7081 ttattcaaat ataaaatata gagagaagag agagagggaa gatatttata aagggcaaag
     7141 ttatgtttac tcaacttagg aaatagaaat agatcaattt atattctctt gtcaatcgaa
     7201 tatgaacctt agcactatat accaaatata gtaaaatgct gaaagatgt
//
LOCUS       DAZUJR010000112         6410 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.116, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000112 DAZUJR010000000
VERSION     DAZUJR010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6410
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.116"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..212)
                     /locus_tag="ACG804_002610"
     CDS             complement(<1..212)
                     /locus_tag="ACG804_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylate--amine ligase"
                     /protein_id="HFS4833485.1"
                     /translation="MNILILSCGRRCELVNAFKTALNNNEMEGKIIGADCSELAPALY
                     MCDEKIVLPKVSESNYIEELIKVIKF"
     gene            complement(224..2041)
                     /locus_tag="ACG804_002611"
     CDS             complement(224..2041)
                     /locus_tag="ACG804_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HFS4833486.1"
                     /translation="MFILTRRRKIATLVFVDSLLLIAANIAAAKFMKPFVSIPMDLIL
                     ISIGLSIGFYLFYGSLFKVFTRINRYTNLREIIAIFSSLSASAASSILILLFINRRYS
                     LRLVIFAYLLSLLLIIGSRLIWRIYIETKNMRYVSADSAKNTLIVGAGEGGRILYNSF
                     LGSKTAQDIHVVGFVDDDPNKRNTYLSGKKVLGALKDIPELIEKYDIQMVTIAIPSLS
                     RKKLRRIFELVESARVKVNTMPSIEELASGKISVSKLKTIDVVDLLGRDEVKLDIESI
                     KDQITDKVILVTGAGGSIGSEICRQIIQFNPAKLLLLGHGENSIYLIDRELRTHHQNC
                     PTEIVPIIADIQDREKINEIMEQYHPDIVYHAAAHKHVPLMEYNPKEAVKNNIFGTKN
                     VAEAAKAAKVKNFVMVSTDKANNPPNVMGSTKRIAEMIVTGLNEEGCTKFSAVRFGNV
                     LGSRGSVIPVFREQIAQGGPITVTDFRMTRYFMTIPEASRLVIQSGALAKGGEIFILD
                     MSEPVKIVDLAKNMIRLSGYSEDEIEIIETGIRPGEKLYEELLLDKERNDEAVYEKIF
                     VGNIKGYSIQKVMDFVKSLPQDDEQLAKDIVTFANASNR"
     gene            complement(2055..2819)
                     /locus_tag="ACG804_002612"
     CDS             complement(2055..2819)
                     /locus_tag="ACG804_002612"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsB/CapC family capsule biosynthesis tyrosine
                     phosphatase"
                     /protein_id="HFS4833487.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAERLFFELLELGKTPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMTASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPDYEEVKKKKFGLF"
     gene            complement(2847..3545)
                     /locus_tag="ACG804_002613"
     CDS             complement(2847..3545)
                     /locus_tag="ACG804_002613"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004713 - protein tyrosine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0004715 - non-membrane spanning protein
                     tyrosine kinase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HFS4833488.1"
                     /translation="MARTQKQKAAQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLNNAR
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILDEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLNKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            complement(3557..4336)
                     /locus_tag="ACG804_002614"
     CDS             complement(3557..4336)
                     /locus_tag="ACG804_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzz/FepE/Etk N-terminal domain-containing
                     protein"
                     /protein_id="HFS4833489.1"
                     /translation="MEETISLKEIFETLRKHLVTIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDALGFPILG
                     TVPEMSAKELNAGIRKKGTAPARPKATNDKTAPSRRSRSRV"
     gene            complement(4352..5296)
                     /locus_tag="ACG804_002615"
     CDS             complement(4352..5296)
                     /locus_tag="ACG804_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFS4833490.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTLQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            complement(5342..6121)
                     /locus_tag="ACG804_002616"
     CDS             complement(5342..6121)
                     /locus_tag="ACG804_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833491.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKNFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVVIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKISAAYATKAQTVAQQMGYSNISY"
BASE COUNT         1707 a         1322 c         1137 g         2244 t
ORIGIN      
        1 aaaaacttta ttacttttat taattcctca atataattac tttctgaaac tttaggtaat
       61 actatttttt cgtcacacat atatagtgcg ggtgctagtt cagagcaatc tgctccaatg
      121 atttttcctt ccatttcatt attgtttaat gctgttttaa atgcattcac tagttcacaa
      181 cgacgtccac aacttaatat taaaatattc aatttttaat ctcctatcta ttcgaagcat
      241 ttgcaaaagt gacaatgtct ttagccaatt gttcatcgtc ttgcggcagg ctcttgacaa
      301 aatccatcac tttttgtatt gagtaacctt tgatgtttcc tacaaagatt ttctcataaa
      361 ctgcttcatc atttctttcc ttatccaaca atagttcttc atatagtttt tcccctggac
      421 ggatacctgt ttcaatgatt tcgatttcgt cttcgctata cccgctcaat cggatcatgt
      481 ttttcgctag gtctacaatc ttcactggtt cactcatatc tagaataaaa atttcgccac
      541 cttttgctaa tgcgccagat tgaataacta aacgactagc ttcaggaatc gtcataaagt
      601 atcgagtcat acgaaagtct gttacagtga ttggaccacc ttgagcaatt tgttctctga
      661 atactggaat cacactaccg cgagaaccaa ggacattccc aaatctgaca gctgagaatt
      721 tcgtacagcc ttcttcattc aatccagtca caatcatttc agcgattcgt tttgttgaac
      781 ccatgacatt tggaggattg ttagctttat ctgtcgatac catgacgaag tttttcactt
      841 ttgctgcttt agctgcttct gctacatttt ttgtaccgaa aatattgttt ttgactgctt
      901 cttttggatt atattccatc agtggtacat gtttatgagc agctgcatgg tagacgatat
      961 ctggatgata ttgttccatg atctcattga ttttctcgcg atcttggata tctgcgatga
     1021 tcggtacgat ttctgtagga caattttgat gatgcgtgcg taactcacgg tcaatcaagt
     1081 agatcgagtt ctccccatgt cctaaaagca atagctttgc aggattgaat tgaatgattt
     1141 gccgacagat ttctgaaccg atcgatcctc ctgcgccggt gacaagaatg actttgtctg
     1201 tgatctgatc tttgatggat tcaatatcca gctttacctc atctcttccc agtaaatcca
     1261 ctacgtcaat tgtttttaat tttgatacgc taattttccc tgaagcaagt tcttctatag
     1321 aaggcatcgt gttgactttc acacgagcgg attcgactaa ctcgaagatt cgtcgtaatt
     1381 tttttcttga taaggaaggg atagcgatcg ttaccatttg aatgtcatat ttttcaatca
     1441 attccggaat atcttttaat gcacctaata ctttttttcc tgaaagatac gtatttcttt
     1501 tatttggatc atcatctaca aacccgacaa cgtggatatc ttgagccgtt ttggatccaa
     1561 gaaagctgtt gtataaaata cgcccgcctt cgccagcacc aacaatcaat gtatttttag
     1621 cagaatctgc tgatacgtat ctcatatttt ttgtttcgat gtagatacgc cagatcaatc
     1681 ggctaccgat gatcaataag agcgaaagca gataagcaaa gataactaac cgtaaactgt
     1741 atcgccgatt aatgaacagc agtatgagga tacttgaggc agcacttgca gatagtgaac
     1801 taaaaattgc aatgatctct cttaaatttg tatagcgatt gatccgagtg aaaactttga
     1861 ataaactacc ataaaataaa taaaaaccaa tcgacaaacc gatagagatt aaaataagat
     1921 ccattggtat agatacaaac ggcttcatga atttagctgc tgcaatattt gcagcaatta
     1981 ataacaagct gtccacaaaa accaatgtgg caatttttct tcttcttgtt aatataaaca
     2041 ctttttaatt ccccctaaaa taaaccaaac ttcttctttt ttacctcttc atagtctgga
     2101 taactgattt catccccgtt gatcagatcc tttgcaactt gcttcatctg tactactttt
     2161 tccttaccaa agtccttggc aatctgctca tagcactctt ttaagtaaaa ggtgcgctta
     2221 gagactccgt gtgcatcaga agcagtcatc tgcacgagat tatgtttgac cattgtttta
     2281 gctgttttct gaatatcttt gccaaatacc ccaacataac ttggcgcagt aagttgggcc
     2341 aaacacccca tatctaggaa cggaagcaaa tgattcgggt cttcgcgaaa atgcgcgttg
     2401 cgttctggat ggacgatcac tggtgtcttt cctagttcta acaactcaaa aaaaagccgt
     2461 tctgcatata acggcacttc cagtgtcgga aattcgatca gaagatatgt atcatctaaa
     2521 tctgtaaata aaatttcatc tcggtggatg tcttcgatga gcgttccggt aatacgtact
     2581 tcttgtcctt ccaataacgt caaaggcaac tgtcttttct ctaattcggc ttgtaacgaa
     2641 gcgactagag aaatgacttg tgatttttca ttgctgtatt ttccattatt gtggtgtggt
     2701 gtgcataaaa tatgcgtgat gccttgctga atcgcttttt cagccattgc aatacttgct
     2761 tctaagtttt ctgccccgtc atcgattcct ggtaggatat ggcaatgtag atcgatcatt
     2821 tctcttgtct cctctcttct tattccttaa tttccgtagt aataaccagc atctttgcta
     2881 tgttctgctc cgttgtatac aacacctaaa actcgtgctt gtaccatctc tagcagttct
     2941 tttgctttat tcaatgattc tttacgtgat gtattttcac gtacgaccaa taaagtgcca
     3001 tccgtttttg aagacatgat ctgtgcatct gttacggcta ctactggtgg catatcgaat
     3061 atcaccacgt caaataactg tcttgcttcg tctaggatct gatccattct tggcgaactt
     3121 aacaattctg atgggttggg tggcttaggt ccactaggca aaatcgacaa gttctcgact
     3181 ggcgttcgtt ggattacatc tgctacactt cctgatgaac taagtgctgt acttaatccc
     3241 ctggcattgt tcagctggaa tgtcttatag acgacgggtt tacgtaaatc tgcatcgact
     3301 agtagaactc gttgaccgga tttagcaaaa acgactgcaa tgtttgctgc agtggtggat
     3361 tttccttctc caggacctga tgaagtcacg acaatcgttt tgatttgctg accagctgcg
     3421 gaggcaaact ggatattcgt ccggatcgta cgatattgtt cggcgattgg tgaagatggg
     3481 tttgttaatg tgatcaaact gactgcatga gtttgtgctg ctttttgttt ctgtgttcgt
     3541 gccatttttc ttcctcctag actcttgagc ggcttctgcg tgatggggct gttttatcgt
     3601 ttgtagcttt tggtcgtgca ggagctgttc cttttttacg gataccagcg ttcaattctt
     3661 tcgctgacat ttctggaact gttcctaaga ttgggaatcc taatgcatcc gtcacatatt
     3721 tttcatcttt cactgtccga tcaagtaatt cgaataagaa tgccagacct acgcctacca
     3781 tcattcctaa tactaagcca atcactagat tcaatttatt atttggcgaa acaggtgtcg
     3841 tattggcaac tgcacctgaa ataatcgaga ttttatcgac attcatcacg tcttttgcgt
     3901 tctcttggaa aacttgtgaa gttgtgttag cgatctgttg agcagtcact gcattcgtgc
     3961 ttattgcctg gatcgagaac atttgtgaat tttgtgactg attgacggag atcgcatctt
     4021 tgatttgtcc agcagtcatt ttcacattgt cttctgtttc taaacgatct ttgacttcat
     4081 ttagtactaa atcactgacg atcatatctt tatacgtatt gatcatttgc aggttcgtat
     4141 tgacatcatt gacatttgct gtgtctgatt gtggcagtgt cacgatcaat tgtgcttgtg
     4201 aactgtattt tggtgtcaag atgaaaaatg ttacgattcc tgagatggcc aagccagcaa
     4261 acattgagat gatgattgtt accaagtgtt tgcgtaatgt ttcaaaaatt tctttcaagc
     4321 tgattgtctc ttccattttt tctccacttt cctatttatt ctctagattc atttgatctt
     4381 ttaattcttt tttcacacga tcaagttctt gatcgctgac tttttgatag gagatattat
     4441 cttgcatgaa gccttctcct tgcagctgat cttgcttgat cgtaccaaat gcctcccgat
     4501 aatctaaagc gatttttttc atttcatcaa agctcatgtc tgttttcata ttcgactcta
     4561 gagcattcaa aacggattga tagttgctga caccgtttaa actcaatact ttttttgcta
     4621 caccttctac gatctttctt tgacgctctt gtctaccata gtcaccattt ggatcttcat
     4681 aacgcatacg agaataagat aatgcctgat ccccgttcaa tgtaatttta ccgattggaa
     4741 agtcatagcc atcttgtgag aaagtgaggt cattattgac ttcgatacca ccaactgcat
     4801 caacgagttc ctttagccct ttcatattga tagagacata gtgatcgatt gggatgtcta
     4861 catatttttg tagggtatcc atcgccatgg cagctccgcc gaatgcgtaa gcgtggttga
     4921 tcttgtcttt tgtgtcacga cctacgatgt cgacatacgt atctcgagga atgctgacga
     4981 tcgttgtctg tttgtcttca ggactgactg tggcaaccat catcgtatct gatcttcctt
     5041 gatcgacccg acctaaatct ccagtatcaa tgcccatcaa tagaacagag aaagattctt
     5101 gtttgtccag atcaactggt ttcgttcgtt ctccttgggt tcgttccact gattcgtaag
     5161 ttttctcaat agaatgtgag agatccagat ataattttgc tcctactcct acaattgcta
     5221 atactaatac gataagaact gctaaaataa tcagaaatat ttttttccct cttgattttc
     5281 ttcttcgtct tgccatagtt tcctccgttt gctaaccttg cttgaatcaa cgttttaact
     5341 gtcaataact tatattgcta tagcccattt gctgagcaac agtttgtgct tttgttgcgt
     5401 atgctgcgct tattttttca ttccggatct gctctatttg actgagcgcc gtcaaatatt
     5461 gatcgtaagt agcggtggca gtcacttgac catccttcaa catcgtatcg aataactgat
     5521 ctagttgcgt gacttgcgcg atctgagtat cagcgaatcc tagatattgc ataacaaccg
     5581 ttttccaagg actatcttta aaaaagctca tattttcacg tacacgagcg acatctgcac
     5641 ttgtcacctt ttctttgatg acgacatcgt ctacagcttg ctgccagttt gatacatttt
     5701 tagtaaataa atcgttgaca gctgtctgga tcttcagttt tgattctgca ctatctaact
     5761 gtgtcacgat tgctttcttc tcatcttgga ttgcaacagc ttctttaggc aattctgatt
     5821 ctttgatgtc gtaatcatct gctgaaagtt tgacagagga tagcttattt gacaaacttg
     5881 tgattgtttc ttctgttatt tcagggttta gaaaattttt ttcttttgta ctatacagct
     5941 tgtctacttc ttttgataaa gaagtcaagg tgtctttttg attggtgatg gcagattctg
     6001 cataattgat ccgttgctga tgttgccgct gattattgat atggtaacca aacaaacaga
     6061 tcgcaatagc acctgcacct accgccacag cagtcaatga cttgacgaat ggcttttcca
     6121 tagattcact cctaagtatt gatgatagat aaattaagat ataattcaca tacataaaaa
     6181 tgacagcttt ttattttaaa aaacataatt aaattaatat attcacagaa atatttgtaa
     6241 acaagttttc cctatataat cataccacaa actattttct tgactagggc aatttacgat
     6301 ttaaaagtaa ataaaacatt aataagataa caattaatcg atttcatttt tatttcctta
     6361 attttcatag gtgtttttaa aagttacaca aaaaataaaa taacaaaaaa
//
LOCUS       DAZUJR010000113         6303 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.117, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000113 DAZUJR010000000
VERSION     DAZUJR010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6303)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6303
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.117"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            334..714
                     /locus_tag="ACG804_002617"
     CDS             334..714
                     /locus_tag="ACG804_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HFS4833492.1"
                     /translation="MSEQHQNLASDHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVAPD
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            696..1610
                     /locus_tag="ACG804_002618"
     CDS             696..1610
                     /locus_tag="ACG804_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HFS4833493.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     TLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPNHQIAIYTHTDKDHIHN
                     HIVINSVNLETGKKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKTEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYTQFCDSLKTFGIHCLNRGKNFTYELVHKKK
                     KVRSNKLGKDYEKETILHELDRRERTYNQQRTNELRRARASIRETAEEVRREQRTFTP
                     EQSEIRPTRRNHEQHVERGTDHQQELSL"
     gene            1855..2544
                     /locus_tag="ACG804_002619"
     CDS             1855..2544
                     /locus_tag="ACG804_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833494.1"
                     /translation="MAFYLPYLLISASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLV
                     GVIFALSIVLSGLFGVLEGNKRVSRSILLGDITQKYEAACDKKKKEQALAQKMEEFTA
                     CYEDMNNIFVDQEKRLTDKNMKKLTRFYQNLPEKQQKEVQEKYEQVKKDVQYFKDTQT
                     EEACCNLFSDTIPFSTSEQERKERQQSVTYERYETLLQQATNIQNPTKKETALNYLES
                     VKEWLDQQQQN"
     gene            complement(2665..2751)
                     /locus_tag="ACG804_002620"
     CDS             complement(2665..2751)
                     /locus_tag="ACG804_002620"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HFS4833495.1"
                     /translation="MFERFICPLLVEVCVSLFSYWLNNRNKK"
     gene            3427..4377
                     /locus_tag="ACG804_002621"
     CDS             3427..4377
                     /locus_tag="ACG804_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HFS4833496.1"
                     /translation="MANEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMREKGDKTVR
                     LTFDQLKDLSNYKATANNRFINDLEMTYDKLMDLRFGKRSANGLDIDRFVMFSEFKIR
                     GTAKDPYVDIQVYEKALPLLNNLDEWVRYSLQQFNELQSSYAKTMFRLLKQYRTKGFA
                     YFSKEDFHELLDIPKSYWNNQANVDNRVIKPIRQELTAIFKGLSIKKKYGKGRGKPVV
                     GYQFTFKPEIKKADDFNKHAPTKEEQNKALALADKQKEYEEPATTINEKIKQKKRELE
                     LLQQIKQLEKEKEALEKQTESALSKKEKKSLLSDLDNLFQ"
     gene            4398..4931
                     /locus_tag="ACG804_002622"
     CDS             4398..4931
                     /locus_tag="ACG804_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFS4833497.1"
                     /translation="MQPQETFTIKELSELFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLGNQMLLDRLHEYEQDNDKNVNIPSKNVVTNKLLDQLREENEFLRE
                     QLALREQNNSHIQKLLDQQQQLTLQANKQIEKLQEKLQLTYTEEAPENDSTTLSEATE
                     TIDKQIDTEKKWWQLWK"
     gene            4947..5117
                     /locus_tag="ACG804_002623"
     CDS             4947..5117
                     /locus_tag="ACG804_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833498.1"
                     /translation="MTRKNLLFGSILLGILGFSPMLLSVINKGNKHGELKLNPNYYNS
                     PNEELFVKETDK"
     gene            5567..6100
                     /locus_tag="ACG804_002624"
     CDS             5567..6100
                     /locus_tag="ACG804_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833499.1"
                     /translation="MKKFTLGVALLTIGAVVLPSTTIVYASENSQVVSLNENNATENV
                     VIEYTEDGMVVTKYEDGYSAEDFANSSDIMTRAAVARWGKKEYTNIAVTTGVAANAIN
                     AAFWAGGKASTSMFGIPGWAIGALLTGASWTKKGASPGNAVAKEWDKNGNGWIGFYYQ
                     RGYDAAGRVVATRYSTL"
     gene            6112..>6303
                     /locus_tag="ACG804_002625"
     CDS             6112..>6303
                     /locus_tag="ACG804_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833500.1"
                     /translation="MFLISKSLKSLKTFTKKNPQIATIRIFIFAIAVAIIVNMLSGGQ
                     LYKSGLFLVLILVVLDIIKS"
BASE COUNT         2324 a         1102 c         1173 g         1704 t
ORIGIN      
        1 aaaaaaaaat aaatcgatac attttagaag aatagggttg tttgaatatt acaaagcaac
       61 aatttcacct tcggtgaaat aagcgaaact ttacaaaaag tggctagcaa atgctagcct
      121 ttttttgtat tgtggagcgt ggattttgag ggggattcaa gggggagctt gcgctccttt
      181 gacaagcggt tatttgcacc aaatacggag gtatttggct agcaaatata gagcttgcca
      241 aaccctttta gtgagcttta ctcattgtac ctttttaggt acaatggtat tgcgaacgat
      301 acgtccgtag gacgtactga aagggtggga cttatgagcg aacaacatca aaatttggct
      361 agcgatcatt ctaaaaaata tacctatcga tccgagccaa aacaaatcag ttttcgagtg
      421 agcgaatccg aatttgcaaa gctgaagcag tcagctgaag ctttgcaaat gagtgtgccg
      481 gctttcgtga aagccaaggc acaaaacgcg cgtctggtga caccgaaagt ggcgccagac
      541 attgcccagg caatcgcgcg cgatttagcc aaagctggag ggaatatcaa tcaaattgcc
      601 aagtggtgca atacacacca acacgacgtt gctcctgatg atgctcaacg tttatccgaa
      661 aacctaaaaa tcatgcaaaa ggagctacaa aagatatggc aacagttaaa gtaagtcgaa
      721 ccacttcatg tagccgagca atcaattacg cagaaccacg agcaaccgtc aaaacaggaa
      781 taaactgtga cattgattat gccaaaagtg aaatgaaaca aatacgcacg ctttatggaa
      841 aagacgatcg tgtacaagca cacttattga ttcagtcctt tcgaccagga gaaattaccg
      901 ctgaaaaagc caatcaacta ggggcagagt atgcgaaaaa aatagcccct aaccaccaaa
      961 tcgcgattta cacacataca gacaaagacc atattcataa tcacattgtc attaactccg
     1021 ttaatcttga aactgggaaa aaatttcaag cccatgggca agcattttta aacaaatgtt
     1081 atgacctaaa tgacgagatt tgtcttgaac atgacttaac aatcacggaa cgaggaaaga
     1141 aaaccgaaaa acgaaccatg tctgaaatta aattaaaaga aaaaaatgaa ccggtttgga
     1201 aagacgaaat tcggtttgcg attgatcaaa caatgaaaaa caaaaaaact cgaacgtata
     1261 cccaattttg tgattcactt aaaacattcg gcattcattg cttgaatcgc ggaaaaaatt
     1321 ttacttacga attggtccac aaaaagaaaa aagtacgatc caacaaacta ggaaaggatt
     1381 acgaaaagga gacgatttta catgagctgg acagacgaga acgaacctac aatcaacaac
     1441 gaaccaacga gctacgaaga gctcgagcta gcattcgcga aactgcagaa gaagtacgaa
     1501 gagaacaacg aacttttacg cctgaacaat cggaaattag accgactcga agaaaccatg
     1561 aacaacacgt tgaacgagga acagaccacc aacaagaatt atcgctctaa aacgttaaaa
     1621 gacatcgaaa acgaaataaa gagacaacgt gcctttcttg cgccttatac ccaagaaagg
     1681 atacaaacta cgatggattc acaagtcaaa aaactccacc aagcgctatt agaccagcga
     1741 aaccaagaac aaaaaaaggc tttaattcaa cgatcgatgg atattcttgc ccccttatgt
     1801 tgcttagtac taacattatt agccttttgg ttggtatggg gagaataaac agacatggca
     1861 ttctatttac cctatctact catttctgcc agtattttag gaattatttg gcttagctat
     1921 aaggcttatc aaacaagata ttcattaaaa ggctctaaaa ttcgatttaa gcgattttta
     1981 ttggtcgggg ttatatttgc cttatcaatc gttttaagtg gtttattcgg cgttttagag
     2041 ggtaataaac gtgtttcaag aagcatttta ttaggggata tcactcaaaa gtatgaagca
     2101 gcatgtgata aaaagaaaaa agagcaagca ttagcacaaa aaatggagga atttaccgct
     2161 tgttatgagg acatgaacaa tatttttgtg gatcaagaga aacgtttaac agataaaaac
     2221 atgaaaaaac tcactcgttt ttatcaaaac ttaccagaaa aacagcaaaa agaggtacaa
     2281 gaaaaatatg agcaagtaaa aaaagacgtg caatatttta aagatacgca gacagaagaa
     2341 gcttgttgta acttatttag cgatacaatc cctttttcaa ccagtgaaca agaacgaaaa
     2401 gaacggcaac aatcggtcac atacgaacgt tatgaaacac tgcttcagca agcaacaaac
     2461 atacaaaatc caacgaaaaa agaaacggca ttaaattatc tagaaagtgt caaggaatgg
     2521 ttggatcagc aacaacaaaa ttgaatttga ttagcaatca tgttaaactg aacctgcaaa
     2581 tgatcaaaca ttagatacac gaaagcccca gagaggtcgg attctctggg gctttttttc
     2641 aggttgatgt cgcctttatt gattttactt cttgtttcgg ttattcaacc aataactgaa
     2701 taaagagaca caaacttcta caagaagggg gcaaatgaac cgttcaaaca ttagatacac
     2761 ctccttccag tcgcaagact gtcggatagg cgacaagtta ttatacctta caaaataaaa
     2821 tctgtgtggt gtttttaagt atcccttatt ttcgggttgt tagggcttgc cctgaccgcc
     2881 tgtaaggcgc tttaagaaca agataaggtt ttttacccaa gactgtctta aaacgactta
     2941 gacgagctat cagaggcttc ccccacctcc gttactgact tgtttttagc aaaggagcct
     3001 ttaggcgact gcgcagtaca atgtgagagc atagcgatca cactttttta gcgaccgtag
     3061 ggagcaaggt tttgaattgg cagttttgaa aaatgcgcga acctgttggt agaaaaaaga
     3121 agtggttttt aggcgggaaa ttttgtcacc ctcttttata atctcttttt aaaccttttt
     3181 ttaaacctct ttaccgtcgg ctgtgtcctt actccttcaa tggatacagc gttttataaa
     3241 ctacattttg tctgctttta aactacattt tgtctgcttt taaactacat tttgtctgct
     3301 tttaaactac attttgtctg cttttaaact ctttttttgc actcacgtat gttataatat
     3361 gcattatcac agacaaaacg ttgtttataa cgtctgtatc cattgaagga gtaaggagga
     3421 atatctttgg caaatgaaat cgtgaaatac catcatgaat taaataccat tccgttgcgg
     3481 aaatttacac cagttgaaat gaatctattt ttctctattg tgtctagaat gcgcgaaaaa
     3541 ggcgataaaa cagtccgtct tacttttgac caactaaaag atttaagtaa ttataaagca
     3601 actgctaata atcgtttcat taatgattta gaaatgactt atgataaatt aatggattta
     3661 cgttttggta aaagaagtgc taatgggctc gatatagata gattcgttat gtttagtgag
     3721 tttaaaatac gtggaactgc taaagatcca tatgtagaca tacaagttta cgaaaaagct
     3781 ttacctttac taaacaattt agatgagtgg gttcgctatt cactccaaca atttaacgaa
     3841 ttacaaagta gctatgcaaa gactatgttt cgattactaa aacaatatcg aactaaaggt
     3901 tttgcttatt tttctaaaga ggattttcat gaactattag atattccaaa aagttactgg
     3961 aacaaccaag caaacgttga taatcgtgtt ataaagccta tacgacagga attaaccgca
     4021 atcttcaaag gattatcaat caaaaagaaa tacggaaaag ggcgaggaaa acctgtcgtt
     4081 ggctatcaat ttacgtttaa accagaaatc aaaaaagcag atgattttaa taaacatgca
     4141 ccaaccaaag aagaacaaaa taaagcattg gctttagctg ataaacaaaa agaatacgaa
     4201 gaacctgcta caacaattaa cgaaaaaatc aaacagaaga aacgagaact tgaactcctc
     4261 caacaaatca aacaactaga aaaagagaaa gaagctcttg aaaaacaaac agagtccgca
     4321 ctttcgaaaa aagagaaaaa aagtttatta tctgatttag ataatttatt ccagtagcaa
     4381 cctaggaggc aaccagtatg caaccacaag aaacctttac aataaaggaa ttgtcagaac
     4441 tttttaagat gagtaggcaa gcaatatcga aacatatcca aaaattagat tcttccatga
     4501 tagctaaaaa tgagcgtggt tataaggttg tattgcgttc tggagtattg caacttgctc
     4561 gcaacttagg caaccaaatg ttgctagata ggttgcacga gtacgaacaa gacaacgata
     4621 aaaatgttaa tataccaagc aaaaacgtgg ttacaaacaa gttgctagat cagttgcgtg
     4681 aagaaaatga atttttacga gaacaacttg ccctcagaga gcaaaataat tctcatatac
     4741 aaaaactact cgaccagcaa caacaactca ccctacaagc caacaaacaa atcgaaaaac
     4801 tgcaagaaaa actacagttg acttatacag aagaagctcc agagaatgac tcaacgactc
     4861 tttctgaagc aacagaaaca atagacaaac aaattgatac tgaaaaaaaa tggtggcaac
     4921 tttggaaata actggaggga acattcatga caagaaaaaa tcttctattc ggttctattt
     4981 tactaggaat tctaggattc agtccgatgt tattgtcagt gatcaataaa gggaataaac
     5041 atggtgaatt gaaattgaat ccaaattatt acaacagtcc taacgaagaa ttgtttgtaa
     5101 aagaaacaga taaataataa aaaagactgc tctttcgagc agccagttaa aaaataatga
     5161 gtgtttattc ttgaaaaagc aacgcgctta tgaagcgcta ccaaaaattt atcatatttt
     5221 attaaaaata acaacccagt aaaaaatgac tggtaaaaat tcacaaagaa acggaaagaa
     5281 gcaaccgcag aaaatcaagc ttaaaaagag cttttgacct agaccaatcg aaaatcacaa
     5341 agtgagcgcc tgtatctatt gctacaggcg ctacttggca tagtatacat tatgtcaaca
     5401 agaatttaat ataacatatt ttcctaatgc attctaacta taccacatta tcaaaaatat
     5461 aaattatctt tactaaataa aatattgaca agcctatacc ttttgtttta tgattttcac
     5521 aaagaaaacg ttttctatat atttttctgt atcaggagga aattctatga aaaaatttac
     5581 tttaggggta gctttgttaa ctattggggc agttgtttta ccgtcaacta ctatagttta
     5641 tgcttcagaa aattcccaag tggtatcatt aaacgaaaac aatgctactg aaaatgtagt
     5701 tattgagtac actgaagatg gtatggtcgt aactaaatat gaggatggtt atagtgcgga
     5761 agattttgca aattcttcag atatcatgac aagagctgca gttgcaagat ggggcaaaaa
     5821 ggaatataca aatattgctg taaccactgg agtagctgct aatgctatta atgctgcctt
     5881 ttgggcagga gggaaagcta gcacttctat gtttggtatc ccaggttggg caattggtgc
     5941 tttgttaaca ggtgcaagtt ggactaaaaa aggtgcttct ccagggaatg cagttgcaaa
     6001 agaatgggac aaaaatggta atggctggat tggattttat taccaaaggg gatatgatgc
     6061 agctggaaga gttgtagcta ctagatattc aacgttataa gttaaggagt gatgtttttg
     6121 atatctaaat cattaaaatc attaaaaaca tttactaaaa agaatccgca aatagctact
     6181 attcgtattt ttatatttgc tatagctgtt gctataattg ttaatatgct aagcggaggg
     6241 caattataca aatctggttt atttttagtg ttaatcttag ttgtcttaga cataataaag
     6301 tct
//
LOCUS       DAZUJR010000114         6230 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.118, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000114 DAZUJR010000000
VERSION     DAZUJR010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6230
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.118"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            133..633
                     /locus_tag="ACG804_002626"
     CDS             133..633
                     /locus_tag="ACG804_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HFS4833501.1"
                     /translation="MEQIRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELKGTPIGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCNDMSDVAYYLIVEAGDLGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFELM"
     gene            730..2577
                     /locus_tag="ACG804_002627"
     CDS             730..2577
                     /locus_tag="ACG804_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HFS4833502.1"
                     /translation="MVGNKWYKCDLHIHSTASQCFQDKKVTAKEWVEECLNKGLDCVA
                     LTDHNTGENIDEYKKVAIENGLDFFPGVELTCGENGTHLLVLFDKSACTNDISDFLTK
                     MGIKREDWASAAACSMKSVLEVIDFAEHEGLLVIPAHIDEFNGISSAKFGNLGKIFES
                     ENIYAVQTVQKEFFENRSQMIPSSKRDTIYDSVNARYDGRVGKDTLESWYKSVVEAEK
                     NNMTFLSFSDNPHSKGNSKHGLWGIGTRYSYIKMKDEPDLGSLRDALMLGETRVHSDF
                     SNFSINENEVLLEKLSFSGTTLSTKEVVVEFSDNLTSIIGGRGTGKSCITRFLVYVLG
                     KEAELDQFSEIQSDYQNFAQIEHNGSGIFLKDTIVKLNIFYKGTKYQIIRTQDRHSIY
                     EFTQENGLVEKETERLRMISDKVSIYSQKQIYEISKNQTSILELLDGYNSDLISEYKN
                     EIETCVNEIRKLNWDIVSVKKEIQDKAKVELEIEDLKKQVEKLSHKSYKDVYDEYSKE
                     TDIYRELKRDVEALKEIPKNLTDSVDKIDFGNGIKVTDEIDEHRGELIKNLVTNRAKI
                     QTIINEMSDEIDSYRAELNKSDWKVNYNEVSKRYQRGIKNLVKSYLKMN"
     gene            2580..3476
                     /locus_tag="ACG804_002628"
     CDS             2580..3476
                     /locus_tag="ACG804_002628"
                     /inference="COORDINATES: protein motif:HMM:NF024700.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFS4833503.1"
                     /translation="MLQNLDSLYQSLSKTEERLEEIIQQEIKLKDYQVEVDSAMSRMN
                     KSYQNLYSERSSSSREIFSDITGIEATIQPNRDFNNYVKELRACINKEDTFDSEFGSL
                     IDKLTKNSITNQDIYNDILDIRVSGESSIFSDKKLINSIRKLNDAQVLELQTLKPNDL
                     VVIRLELNGKKVSLSNASAGQKTSAILSMILAYGNSPLILDQPEDDLDSQLINNLIVR
                     SIITKKENRQILIVTHNANIPVNGDSEWLISMGDSKEISADQCGSVDEPNIKPRICTV
                     MEGGEDAFTNRAKRYGFKQIVE"
     gene            3526..3915
                     /locus_tag="ACG804_002629"
     CDS             3526..3915
                     /locus_tag="ACG804_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFS4833504.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEEVFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPSTLVRSVNYVSD"
     gene            3902..>6230
                     /locus_tag="ACG804_002630"
     CDS             3902..>6230
                     /locus_tag="ACG804_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFS4833505.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKFQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDIQTDALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKSLKKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RCYSKLEKLMESKLARRFKVRRVTPSDLTYLIEHIYGEKGIPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPNRCLIEEKPRCLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEISILNLTSKSENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVINELRKDGSPIAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDQEDQSNQKRLRDLEN"
BASE COUNT         2106 a          925 c         1336 g         1863 t
ORIGIN      
        1 gagttttcca aactgattgg cttcttggtg attgctttga ttgcggtagg tctggtcttt
       61 aatgcttctg gtgtgaagga tgtcttactc aatttgttta accgaattgt cggtgcctga
      121 gggggaatca caatggaaca gatacgtgtt tatattgcga accttggaaa atacaatgaa
      181 ggtgagttgg tgggggcatg gtttacccca cccgtcgatt ttgatgaagt gaaagaacgg
      241 attggattaa atgacgaata tgaagagtac gcaattcatg attatgaact gccttttgag
      301 attgatgagt atacaccaat tgaggaaatt aatcggttgt gtggtttagc ggaagagctt
      361 aaaggaacgc caattggtga ggtcgcttca gagattcaac atgccttctt caattctttc
      421 gaggaaatgg tagagcatgt ggatgatatc atctattatc ccgattgtaa tgacatgagt
      481 gatgtagcgt attacttgat tgtagaagct ggtgatttag gcgaagtacc agaacacttg
      541 aagacgtata ttgattttga tgcgtgtggt cgagacttgg agattggcgg gaattatttg
      601 gttacgagtc gaggggtttt tgaactaatg taaatcattt gttagaattg accagaaatt
      661 tctatcgtac ttttactttt ctatttgata tactgaaata gaaaatattt gttgataggg
      721 gtgttactaa tggttggcaa taagtggtac aaatgtgatc ttcatattca ttcaactgcg
      781 agtcagtgct ttcaggataa aaaggttact gctaaggaat gggtagaaga atgtttaaac
      841 aaaggactcg attgtgttgc attaactgat cacaatacag gggaaaatat tgatgaatat
      901 aagaaagtgg ctatcgaaaa tggcttagat ttttttcctg gagtggaatt aacgtgtgga
      961 gaaaatggaa ctcatttact agtcctattt gataaaagtg catgtacaaa tgatatctct
     1021 gatttcttaa ccaagatggg tataaaaaga gaggattggg ccagcgctgc agcttgctca
     1081 atgaaatcag ttttagaagt tattgatttt gctgagcacg agggcttgct cgttattcct
     1141 gcacatatag atgagtttaa tggaatttct tcagcaaaat ttggaaatct aggaaagata
     1201 tttgaatcag aaaatatata tgcagtacag acggttcaaa aagaattttt tgaaaatcgc
     1261 tcacaaatga ttccctcatc taagcgtgac actatctatg atagtgtgaa tgccagatat
     1321 gatggtagag ttggaaaaga tactttggaa tcttggtata aatcagttgt tgaggcagaa
     1381 aaaaataata tgacatttct tagcttttct gataacccac actcgaaagg aaattcaaaa
     1441 catggacttt ggggaatagg cacaagatat tcctatataa aaatgaagga cgaacctgac
     1501 ttgggatcac ttcgcgatgc tttaatgcta ggcgaaactc gagttcattc tgatttttct
     1561 aatttctcca ttaatgaaaa tgaagtttta ttggaaaaat taagcttttc tgggaccact
     1621 cttagcacaa aagaagttgt agtcgaattc agcgataatt taacttcaat tattggagga
     1681 agaggaacag gcaaatcttg tattacaaga ttcttggtct atgtccttgg aaaggaagca
     1741 gaacttgatc aattttctga aatacaaagt gattatcaga actttgcaca aattgaacat
     1801 aatggctctg gaatattttt gaaggataca attgtgaaac tgaatatttt ctataagggg
     1861 acaaaatatc aaataataag aacacaggat agacattcta tttatgaatt tacacaagag
     1921 aatggtctgg ttgaaaaaga aacagaacgg ttgagaatga tttccgataa ggtgagtata
     1981 tactctcaaa aacaaattta tgaaatttca aaaaatcaaa ctagtatact agaattacta
     2041 gatggatata actctgattt gatttcagag tataaaaatg agattgaaac atgtgtaaac
     2101 gaaataagaa aattaaattg ggatattgtt tctgtgaaaa aagaaataca agataaggcg
     2161 aaggtagagc ttgaaattga agatttaaaa aaacaagtag aaaagctatc tcataagagt
     2221 tataaagatg tttatgatga gtattcaaaa gagacagata tttataggga actgaaacgt
     2281 gatgtggagg cacttaagga aattcccaaa aatctaactg atagtgttga caaaattgac
     2341 tttggcaatg gtataaaagt tacagacgaa attgatgaac accgcggaga attgattaag
     2401 aatttagtga ccaatcgggc taagattcaa acaataatta atgaaatgtc agatgaaatt
     2461 gatagttata gagcagagct gaataaatca gattggaaag ttaactataa tgaggtttca
     2521 aagaggtatc aaagaggtat caaaaactta gtgaagagtt atctcaagat gaattaaaaa
     2581 tgttacaaaa ccttgattct ttatatcaat ctttatcaaa aactgaagag cgattggaag
     2641 aaattattca acaagaaata aagcttaaag attaccaagt tgaggttgac tcagcaatgt
     2701 caagaatgaa taaatcatat caaaatctct attctgagag aagtagttcc tcgcgcgaaa
     2761 ttttttctga tattacagga atagaggcta ctattcaacc aaatagggat ttcaataatt
     2821 atgttaaaga gctcagagct tgtattaata aggaggacac ttttgacagt gagtttggat
     2881 ctcttattga taagctgaca aaaaattcca ttactaatca agatatatat aatgacatac
     2941 ttgatataag agttagtggg gaaagtagta ttttttcaga taaaaaatta atcaattcta
     3001 taagaaaatt gaatgatgca caagttcttg aattacaaac ccttaagcca aatgatttag
     3061 tagttatccg acttgaacta aatggaaaaa aagttagttt atcgaatgct agtgctggtc
     3121 aaaagacatc tgcaattctt tctatgattt tggcgtatgg aaattcacca ctcatattgg
     3181 atcagcctga agatgatttg gatagtcaat taattaataa cttaatcgta agaagtatca
     3241 ttacaaaaaa ggaaaacaga caaattttaa ttgtaactca taatgcaaat atcccagtta
     3301 atggtgattc agaatggttg attagcatgg gagattcaaa agaaatatcg gctgatcagt
     3361 gcgggtcggt agatgaaccc aatatcaagc caagaatatg tactgtgatg gaaggtggcg
     3421 aggatgcttt tacaaataga gcgaaacgct atggttttaa acaaattgta gaataacact
     3481 agagggtgag acatattatt atgtccgccc tttttaggag gaaaaatgaa aaaaataaaa
     3541 agctatacca gtatctgggc agttgaaaaa gtcatttacg caatcaatga ttttcagttg
     3601 ccttttcctg tgacttttaa ccaaatggct tggttcgttt tatctttact gtttgtcatc
     3661 gtatttgccc atgtgcctcc actatctatg atagaggagg tctttttaaa atacttaggc
     3721 ataccggtgg ctgtcacttg gtttatgtcg caaaagacgt ttgatggcaa gaaaccactg
     3781 ggatttttac gatcctttat cagctatcac ttgcgattta aggtgacttt tgcaggaaag
     3841 aaagtcaaag aacagaagaa acgatgggat gaacccagta ctcttgtaag gagtgtgaac
     3901 tatgtatccg attaagtata ttgaaaataa tctcgtcttt aaccaagaag gcgagtgttt
     3961 tgcctactat gaattagtgc cttacaatta ctcctttttg tcacccgaac agaaatttca
     4021 agtgcatgat aactttcgcc aactaattgc gcaaaatcgt gaaggcaaga tccatgcgtt
     4081 acaaattgcc acagaaagta gtattcgcgc cacacaagaa cgatcaaaaa aagaaattac
     4141 cggtagactc aaagaagtag cgaaacaacg aattgatata cagacagatg cattagtatc
     4201 catgattggc gatagtcaga ttgattatcg cttttttatt ggctttaaac taattgcgac
     4261 agatgaagaa gtcaatctaa agagtctcaa gaaatctttc ttttctgggc ttcaagaatt
     4321 tgtctatgga gtgaatcatc atttgatggg cgattttgtt tccttatcca atgaagaaat
     4381 tcgctgctat tctaagcttg aaaaattaat ggaaagcaaa ttggctcgaa gatttaaagt
     4441 caggcgagtc acaccgagtg acctgacgta tttgattgaa catatttatg gcgaaaaagg
     4501 gataccgttt gaagaatacg aatttcagct accaaagaaa aagctaaaat cagaaacact
     4561 ggtgaaacgt tatgacttat tacgtccaaa tcgttgttta attgaagaaa aaccaaggtg
     4621 cttacggatg gaacatgaga atcatgagtc gtacgtagcg tatttaacaa ttaatacaat
     4681 tgtgggggag atggaatttc cttcctcaga acttttctat taccagcaac aacaatttac
     4741 attcccaatc gacacaagta tgaatgtaga gattgtgacg aataaaaagg ctttagctac
     4801 cgttcgtaat aagaaaaaag aactgaaaga tttagacaat catgcttacc aatctgacaa
     4861 tgaaacgaat tccaatgtct tagatgcttt ggattccgtg gatgaattgg aaaccacctt
     4921 ggatcagtca aaagaatcta tgtacaaact gagttatgtg gttcgagtga gtgccgaatc
     4981 agtggatgaa ctaaagcgac gctgtgatga agtgctcgat ttttatgatg ataccaatgt
     5041 aaaactagtc cggccctttg gcgatatgat ggggctacat gaagaattct taccctcaag
     5101 taaacgatat atgaacgact atattcagta tgttacgtct gattttttgg cggggcttgg
     5161 ttttggggct actcagatgc taggagaatt agaagggatt tactttggct acaatgtgga
     5221 tacaggtcgt aatgtttacc tgaaaccggc attggcttca caaggagtca agggttcagt
     5281 aaccaatgcg ctggccgccg ctttcctggg ttctcttggt ggaggtaaat cctttagtaa
     5341 caatctctta gtctactatg ctgttttgtt cggtggtcaa gctgtgattg tcgatccaaa
     5401 aggggagcga ggagggtgga aagaaacctt gccagaaatt gcggatgaaa tcagtatcct
     5461 caacttgacg agtaagtcag aaaatcaagg tctgcttgat ccttatgtga ttatgaagaa
     5521 aaagaaagac tcggaaagtt tagcaattga tattctgact tttttaacag gaatttcaag
     5581 tcgagacggg gagaagtttc ctgtgttacg taaagccatt cgaacggtga ctcaaagtga
     5641 tcaacggggg ttattacaag ttattaacga attgcgaaaa gacgggtcac caatcgcgga
     5701 aaatatcgcc gatcatatcg agtcctttac cgattatgat tttgctcatt tgcttttctc
     5761 agacggctcg attacccaat cgattagttt agataaacag ctaaatatca ttcaagtggc
     5821 ggatttggtt ttaccggatg cagaaacgac ttttgaagaa tataccacca tggaattgct
     5881 tagtgtttcg atgctaatcg tcatttccac ttttgccttg gactttatcc atagtaaccg
     5941 agaaatcttc aaaattgtcg atttggatga ggcttggagt tttcttcaag tggctcaagg
     6001 aaaaacgtta tcgaataagc ttgttcgtgc tggtcgggcc atgaatgctg gggtctattt
     6061 cgtcactcaa aatagcgacg atttattaga tgaacgttta aaaaataata tcgggttgaa
     6121 gtttgctttt cgcagtaccg atattcatga aatcaagaaa accttggaat tctttggttt
     6181 ggatcaggag gatcaaagca atcaaaaacg cctgcgagat ttggaaaacg
//
LOCUS       DAZUJR010000115         6227 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.119, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000115 DAZUJR010000000
VERSION     DAZUJR010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6227)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6227)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6227
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.119"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(99..1229)
                     /locus_tag="ACG804_002631"
     CDS             complement(99..1229)
                     /locus_tag="ACG804_002631"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HFS4833506.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="ACG804_002632"
     CDS             complement(1878..3080)
                     /locus_tag="ACG804_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4833507.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="ACG804_002633"
     CDS             complement(3140..3343)
                     /locus_tag="ACG804_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HFS4833508.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4549)
                     /locus_tag="ACG804_002634"
     CDS             complement(3485..4549)
                     /locus_tag="ACG804_002634"
                     /inference="COORDINATES: protein motif:HMM:NF014537.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFS4833509.1"
                     /translation="MDSLQEEVVPVNRVLIDYLTIHFFSNQHLKLIEEIIEMPIERFE
                     ELDYAPKGYIGQYVWNQVITIRYSIDDAVKGTVMEFSGQGCKHLARWLKTRKTNWQQF
                     FRKVLDYQGNFTRIDFTLDDFVGSLSIPELKHKVILGHVWTTFQVSESHGGTDIINNE
                     SNGETLYLGSKKSQCRFCFYQKDHEQRKRRGIPLEEAKVKNRFELRYRKEKAQSLAKI
                     ISKTHDLTKLFFELLNGAICFYDRDPNDLGAKVDAKWAAFISNYGAITISLDTIPQSF
                     EKTMSWLIHGVSPSLVFIAQVDQTFHSSLLPLIIEQGEMNPRQIKLLQNMKADPEYYQ
                     EEVEYYERKLQSISNEKTSY"
     gene            complement(4610..4717)
                     /locus_tag="ACG804_002635"
     CDS             complement(4610..4717)
                     /locus_tag="ACG804_002635"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4833510.1"
                     /translation="MNQVNQHDLGEAIRVSREERGWTQRYLAEKVGISR"
     gene            4880..5692
                     /locus_tag="ACG804_002636"
     CDS             4880..5692
                     /locus_tag="ACG804_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4833511.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
BASE COUNT         1841 a         1283 c          993 g         2110 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgc
//
LOCUS       DAZUJR010000116         6205 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.120, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000116 DAZUJR010000000
VERSION     DAZUJR010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6205)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6205)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6205
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.120"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(405..779)
                     /locus_tag="ACG804_002637"
     CDS             complement(405..779)
                     /locus_tag="ACG804_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFS4833512.1"
                     /translation="MKLNGLQHIGIPTKDFGASKIFYESLGFSLINEEMNVGSKVGFF
                     ELNGTIIEIWEDKTTECRGAIDHLALDTDDIDEVFNSIQDLGYELLDKNIMELPFWEN
                     GIRYFNFYGPNHEIIEISQMKK"
     gene            complement(802..2202)
                     /locus_tag="ACG804_002638"
     CDS             complement(802..2202)
                     /locus_tag="ACG804_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HFS4833513.1"
                     /translation="MQKIFYKPKDFWFGDCMPFYKDGTFYLFHQRDTRNPKPLTDPFG
                     WSLVTTTDFVKFEEYGEVIHRGGNDDIDQYIYAGSIVQGINEYLALYTGHNRKAKLDG
                     KTSEVLMIASSKDLIHWKKDGEAAKLVPQEGYDKNDWRDPFAIFDQDHGKYVLILGAR
                     KPASKKKPTGRLVYFESEDLKDWNFKGDYWANNEFNMIEMPDIFEIDGTWYLLFSEYC
                     EDKKTKYRVGAGLFSDWKSPVDEAFDGKAYYAARTVGTNETGRFLTGWVATKEGENDQ
                     NNWDWGGALVPHQIIQKTDKTLGVKLPEKIIENFKEITPFSSFKLEKEFGKKERVIVP
                     KIEDYFLFETTLTITSLTKEFALKLFVDSDTQEGYEFRISLINNQLTFGKTPNYPWPQ
                     MFDKGLQRPLFLEIGKEYELKLIVDDTIAVLYIDNVALSTRMYDKVGTALSMTVTEGA
                     IKVDKLDYSINYECGF"
     gene            complement(2206..2616)
                     /locus_tag="ACG804_002639"
     CDS             complement(2206..2616)
                     /locus_tag="ACG804_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFS4833514.1"
                     /translation="MEFIITSHGNIAIGFVDTLKMFFGDNLNCHVVTLGDAGIEEFRE
                     NIEKIVSQVKNQEVMVFADLIGGTPFNEFAKRSEVFQNGFQLLGGMNLGILIEAVNLR
                     LQGKKSDDIIENLRNMNTIACLADMQRHTNEEDE"
     gene            complement(2634..3125)
                     /locus_tag="ACG804_002640"
     CDS             complement(2634..3125)
                     /locus_tag="ACG804_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HFS4833515.1"
                     /translation="MDEKMKGIIHVRIDDRMIHGQVATQWTNQLSANRIMVINNEVAN
                     DDVKKAVVRLAAPPNVRTSIITREVAVKNILSGKYEGQKVLIVAVSPIDVKFLIDNGL
                     PITSVNVGNLSRRNGTERIRPTINITEEEREAFKELISDGVEVTVIQTPRDSKEFLKD
                     FIY"
     gene            complement(3135..3926)
                     /locus_tag="ACG804_002641"
     CDS             complement(3135..3926)
                     /locus_tag="ACG804_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFS4833516.1"
                     /translation="MNKKLTKIDKQVIFRWILNGATSLNYEKMEGLGYAYSMLPFIKD
                     TYKDDPEGMKQSVLAHLQFFNTTPYTAPYIIGMNVGIEKEEKNKSLEAVSALKTGLMG
                     PLAGIGDSVFVVIPWTIFGAIAANMALEGSFVGIILWILASILLRITAYPLYLAGKES
                     GASLLTQIETKLKSITDAVSILGLMVVGALIATVVKVNVGFEFKQGDLTMTGNEIFDQ
                     VMPGLLPACVVAIVYYLLGRKVKPVYVILLILVVSIALRALNILK"
     gene            complement(3919..4692)
                     /locus_tag="ACG804_002642"
     CDS             complement(3919..4692)
                     /locus_tag="ACG804_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFS4833517.1"
                     /translation="MAFWQTFLVVLYGFFINWDKEGPKIGTSQPVVAGFLTGLIMGDI
                     QTGLYIGGTLQLMTLGITSFGGASVPDYQTAALIGTYLAISTNQDASIGITLAIPVAM
                     LIVQLDVLKWSTNIFFQQKAEKFAQKEDYQKLEWMQYLASINTSFVSGIPVLLTVILG
                     PTLVGSAINYIPEWVTGGLKVAGGLLPAVGIGMLLKYLPTKDYFAYLLVGFVLAVYFQ
                     IPILGISLLGAAIALIVYKNRSNNTQVAPAATGGFDEDE"
     gene            complement(4848..>6205)
                     /locus_tag="ACG804_002643"
     CDS             complement(4848..>6205)
                     /locus_tag="ACG804_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFS4833518.1"
                     /translation="FIALRNYVVNKISPIIDSTGLCLLDEFLADISLFIMFIDVIEET
                     SRNFLLSKFRKFRMKNDKQKLLANEIWSSLEVEESKQELLLKWILFLVKKFYVKIPET
                     HCLIVMHGKITASAIARETNKLLNTYVYEAFDMPIEGETSDLINLINNFCKSIDTTNG
                     LILLVDMGSLEQMYEKIESNVIGDLVILNNVSTALAIECGIQVCQKKPISHFYQMDFD
                     SFQVKVQYYKGLSQKKNVIVSCLSGEGISEKVKDILKRYLDNQVEILIFDFNALKKIA
                     KEKDTMIFKNTICVLSTTEFYIQGIDCLNLENLINGNQTLEKLNKYMDSDSCEFCLNE
                     LVKLFTIEGASTKLRFLDSKKVFNEIEKVLYLYEKYYDVKIPSFLRINLFLHLSGMIE
                     RIMIGDGITNEHLKEGAQLFDTFLNVSKDFFSEIKDIYCIEIPKGEYELIYTIFEQTI
                     F"
BASE COUNT         2000 a         1231 c          797 g         2177 t
ORIGIN      
        1 taggagtgag catttttcga aaaatactaa aaatttttca aaataaaaaa aggcatacag
       61 acaataaact gtctatacgc ctcacagact ctattctata catctaattt tggctgtcct
      121 gcaaaaaata tgtgttagcc tccatcgaaa gatcaaactt tggaaaacat cattataact
      181 ttgcttggta agagctttgc taaaacatga tatgacttgt atacaaaatg tggagtgtat
      241 tccaataaat aggaaggatt acaaaatttg aaaccaaata agtaaaaaat actgtcactt
      301 tgaattaatt tgaaatagta aattctcatt aaactattga aatgctgata ccaaaaaatg
      361 aagtactttt cgttcatacc aacttagagc acttcgttat ctatttattt cttcatttgg
      421 cttatctcta taatctcatg atttggtccg tagaaattaa agtaacggat tccattttcc
      481 cagaacggta attccataat atttttatct aataattcat atcctaaatc ttgaattgaa
      541 ttgaatacct catctatgtc atccgtatct aatgctagat gatcaatggc tcctctacac
      601 tcagtagttt tatcttccca tatttctatt atcgttccat tcaactcgaa aaagccgact
      661 ttacttccca cattcatttc ttcattaatc agactaaacc ctaaggattc ataaaagatt
      721 tttgaagctc caaaatcttt tgttggaatt ccaatatgtt gtaaaccatt taatttcact
      781 tacatcatcc cttcaattgt tttaaaatcc acattcataa tttattgaat agtctagttt
      841 atctaccttg attgctccct ccgtaacagt catacttaat gctgttccga ctttatcata
      901 cattctagta cttaaagcaa cattatcaat atataaaaca gctatcgtat catcaacaat
      961 taactttagt tcatattctt tgcctatttc caaaaatagt ggtcgttgca gccccttatc
     1021 aaacatttga ggccaaggat agttcggagt ttttccgaaa gtaagctgat tattaatcaa
     1081 tgaaatacga aattcgtatc cttcttgagt atcactatct acaaataatt ttaaagcaaa
     1141 ctcctttgtt aacgatgtaa tagtcaaagt tgtttcaaat agaaaataat cttcgatttt
     1201 aggaacaatt actctttctt tttttccaaa ttctttctct aacttaaaac ttgaaaatgg
     1261 agtgatttct ttaaaattct caattatttt ttcaggcagt ttaacaccaa gagttttgtc
     1321 tgtcttttga ataatttgat gtggaacaag tgcaccgccc caatcccagt tattttgatc
     1381 gttctcccct tcttttgttg ccacccagcc agttagaaaa cggccagttt cattagttcc
     1441 gactgttctt gctgcataat aggcttttcc gtcgaaagct tcgtctactg gtgatttcca
     1501 atctgaaaat aatcctgctc cgactcgata tttagtcttt ttatcttcac aatactctga
     1561 aaaaagtaaa taccacgttc catcaatttc aaatatatca ggcatttcaa tcatgttaaa
     1621 ttcattatta gcccagtagt ctcctttgaa attccaatct tttaaatctt cggattcaaa
     1681 atagaccaat ctccccgtcg gctttttctt acttgctggt tttctagctc ctagtatcaa
     1741 aacgtatttt ccatgatctt gatcaaaaat tgcaaaagga tcgcgccaat cattcttatc
     1801 atatccttct tgaggaacaa gttttgctgc ttcgccatcc tttttccaat gaattaaatc
     1861 tttagaactt gcaatcatta acacttctga agtttttcca tccaacttag ctttgcgatt
     1921 atgtccagta tacaaagcta aatactcatt gattccttgg acaatacttc cagcgtaaat
     1981 gtattgatca atgtcatcgt tgccaccacg atgaattact tccccgtatt cttcaaattt
     2041 cacaaaatca gtggttgtaa ctagtgacca cccaaaagga tcagttaaag gtttaggatt
     2101 tctcgtatct cgttgatgaa atagataaaa agttccatct ttataaaaag gcatgcaatc
     2161 cccaaaccaa aaatctttag gcttgtaaaa aattttttgc atttatcact catcctcttc
     2221 gttagtatgt ctttgcatat ctgcaagaca cgcaattgta ttcatatttc ttagattttc
     2281 gatgatatca tcgctttttt ttccttgtaa tctcaaattg acagcctcaa tcaaaattcc
     2341 taaattcatg ccaccaagaa gttgaaaccc attttgaaat acttcacttc ttttagcaaa
     2401 ttcgttgaaa ggtgttccac caatcaagtc agcaaatacc ataacttctt gattttttac
     2461 ttgagaaact attttttcaa tgttttcacg gaattcttca atgcctgcat ctccaagtgt
     2521 taccacatga caatttaaat tatcgccaaa aaacattttt aatgtatcta caaatccaat
     2581 ggcaatattt ccatgagatg taattataaa ctccatccac tcatcctctg ttcttaataa
     2641 ataaaatcct ttaaaaattc ttttgaatct ctaggagttt gtatcactgt cacttcaact
     2701 ccatcactaa ttagttcttt aaaagcctct ctctcttctt cagtaatatt tatcgtcgga
     2761 cggatgcgtt ctgttccatt ccttcttgat aaatttccta cgtttacact tgttattggt
     2821 aaaccgttat caatcaaaaa tttaacatcg attggagaaa ctgcaacaat aagaactttt
     2881 tgtccttcat atttaccaga aagaatattt ttaactgcta cttcccttgt aattattgaa
     2941 gttctaacat taggtggtgc agcgaggcga actacagctt tttttacgtc atcattggct
     3001 acttcattat taataaccat aattctgtta gcactcaatt gatttgtcca ttgtgttgct
     3061 acttgtccat gaatcattcg atcatcaata cgaacatgta taataccttt cattttttca
     3121 tccatattca acacctactt caaaatattt aacgctctta acgcaataga aactactaag
     3181 attaatagaa ttacataaac tggtttaacc tttcgtccta acaaataata cacaattgct
     3241 actacacatg caggtaataa accaggcata acttgatcaa agatttcatt tccggtcatt
     3301 gttaagtcgc cttgtttaaa ttcaaagcca acattcactt ttacaactgt ggcaatgagt
     3361 gcaccgacca ccattaaccc taaaattgat actgcatcag taatagactt taattttgtt
     3421 tcaatttgag ttagtaggct cgcacccgat tctttcccag caaggtataa aggataagca
     3481 gtaatcctta ataaaattga tgccagtatc cacaaaataa ttccaacaaa actaccttcc
     3541 aatgccatat tagctgcaat tgctccaaaa atagtccatg gaataactac aaatacacta
     3601 tctccaattc ccgctaaagg acccattaga cctgttttca gagcacttac tgcttccaaa
     3661 gacttatttt tttcttcttt ttcaattcca acattcatac caataatgta aggcgctgta
     3721 tacggcgtag tgttaaaaaa ttgtaagtga gctaaaacgg attgtttcat tccttcagga
     3781 tcatctttat atgtgtcctt gataaaagga agcatagaat acgcataacc caacccttcc
     3841 attttttcat aatttaatga agttgcacca ttgagaatcc accggaaaat tacttgtttg
     3901 tcgatttttg tcagtttctt attcatcttc gtcaaaacct cctgttgcag ctggtgctac
     3961 ttgagtatta tttgatctat ttttatatac gattagtgcg attgcagcgc caagtaacga
     4021 aatccctaaa attggtattt ggaaataaac tgccaaaacg aaaccaacta acaaataggc
     4081 aaagtaatct tttgtaggta aatatttaag tagcattcct atcccaacag caggtaatag
     4141 tccccctgct acctttaaac caccggtaac ccattcagga atataattga ttgcacttcc
     4201 cactaacgtt gggcctaata tcacagttaa caaaacagga attccagata caaagcttgt
     4261 attaattgat gccaaatatt gcatccactc taatttttga taatcttctt tttgtgcgaa
     4321 tttttctgcc ttttgttgaa aaaaaatgtt tgttgaccac tttagaacat ctagttgtac
     4381 aattaacatt gctaccggta ttgctaaagt tattcctata gaagcatcct ggttagttga
     4441 gattgctaaa taagtaccga tcaatgctgc tgtttgataa tccggtactg atgcaccacc
     4501 aaaactagta atacctagtg tcattaattg caaagtccca ccgatataaa gtccagtttg
     4561 aatatctccc ataataagtc cggtcaagaa acctgcaacg acaggttggg aggttccgat
     4621 tttgggccct tccttatccc agttaatgaa aaatccatac aacacaacta aaaatgtttg
     4681 ccaaaacgcc attttgttct ctcctttctt cttatacttt tatataagca attactgtgc
     4741 caactaacat tatccaataa agcgggaaaa tacagtaaat attaattaaa tgagcgtcta
     4801 aatatacttt ggacaccctt tcattttttt agacgctagt atgctattta gaaaatagtc
     4861 tgctcaaaaa ttgtatagat taactcatac tctcctttgg gtatttcaat acagtaaata
     4921 tctttgattt ctgaaaaaaa atcttttgat acatttaaaa aagtatcaaa tagttgcgct
     4981 ccctctttca aatgttcatt tgttattcca tcaccaatca taattcgttc aatcattcca
     5041 gaaagatgta gaaatagatt aattctcaga aaacttggga ttttgacatc gtaatatttt
     5101 tcatacaaat atagtacttt ttctatctca ttgaatactt ttttggaatc taaaaagcga
     5161 agcttagtac tagcgccttc aatagtaaag agtttaacta attcatttaa gcagaactca
     5221 cagctatccg agtccatata cttatttaat ttttctaagg tttgattccc attaattaga
     5281 ttttctaaat ttaaacaatc gattccttga atgtaaaatt cagtggttga aagaacacaa
     5341 attgtattct taaaaatcat agtatctttt tcctttgcta ttttctttaa tgcgttaaaa
     5401 tcaaaaatca aaatctccac ttgattatcg agataccgtt ttaaaatatc cttaactttt
     5461 tcagaaatcc cctcaccaga gagacaagat actattacat ttttcttttg tgataatcct
     5521 ttataatact gaactttaac ttgaaacgaa tcaaaatcca tctggtaaaa atgactaatt
     5581 ggcttttttt ggcaaacttg aatcccacat tcaatcgcta aagctgtaga aacattgttt
     5641 aaaattacca aatcacctat tacattggat tcaatttttt catacatttg ttccaatgat
     5701 cccatatcaa ctagcagaat gagtccattc gtcgtatcta tacttttaca aaaattgttg
     5761 attaggttaa ttaagtcact agtctcacct tcaattggca tatcgaaagc ctcataaaca
     5821 tatgtattca gcaacttatt tgtttccctt gcgatcgcag aagctgttat tttaccgtgc
     5881 ataactatca gacaatgggt ttctggtatt ttcacataga acttctttac aagaaaaagt
     5941 atccatttca acaaaagttc ttgtttactt tcttcgactt ctaaactact ccaaatctca
     6001 tttgccaata atttttgttt atcatttttc atacgaaatt ttctgaactt agacagcaaa
     6061 aaatttcttg atgtttcttc aattacatca ataaacatta taaatagact gatatccgcc
     6121 aagaattcat ctaataaaca tagacctgtc gaatcaataa ttggtgatat tttattaaca
     6181 acatagtttc ttaatgctat aaatt
//
LOCUS       DAZUJR010000117         6174 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.121, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000117 DAZUJR010000000
VERSION     DAZUJR010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6174
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.121"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            725..811
                     /locus_tag="ACG804_002644"
     CDS             725..811
                     /locus_tag="ACG804_002644"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HFS4833519.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1622)
                     /locus_tag="ACG804_002645"
                     /pseudo
     CDS             complement(932..1622)
                     /locus_tag="ACG804_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1629..1907)
                     /locus_tag="ACG804_002646"
     CDS             complement(1629..1907)
                     /locus_tag="ACG804_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833520.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            complement(1867..2781)
                     /locus_tag="ACG804_002647"
     CDS             complement(1867..2781)
                     /locus_tag="ACG804_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HFS4833521.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2763..3143)
                     /locus_tag="ACG804_002648"
     CDS             complement(2763..3143)
                     /locus_tag="ACG804_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HFS4833522.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3593..3880)
                     /locus_tag="ACG804_002649"
     CDS             complement(3593..3880)
                     /locus_tag="ACG804_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFS4833523.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3900..4124)
                     /locus_tag="ACG804_002650"
     CDS             complement(3900..4124)
                     /locus_tag="ACG804_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HFS4833524.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4579..4749)
                     /locus_tag="ACG804_002651"
     CDS             complement(4579..4749)
                     /locus_tag="ACG804_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833525.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(4764..5297)
                     /locus_tag="ACG804_002652"
     CDS             complement(4764..5297)
                     /locus_tag="ACG804_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFS4833526.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5318..>6174)
                     /locus_tag="ACG804_002653"
     CDS             complement(5318..>6174)
                     /locus_tag="ACG804_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HFS4833527.1"
                     /translation="IVSRMREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEK
                     ILSLRFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYS
                     LQQFNELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPI
                     RQELTAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALAL
                     ADKQKEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLL
                     SDLDNLFQ"
BASE COUNT         1634 a         1151 c         1042 g         2347 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa atataacccc tggcaataaa
     1501 aacctcttaa atcgaatttt agagcctttt aatgaatatc ttgtttgata agccttatag
     1561 ctaagccaaa taattcctaa aatactggca aaaatgagta gatagggtaa atagaatgcc
     1621 atttctattt attctcccca taccagccaa aaggctaaca gtgtcatgat taagcaacat
     1681 aagggggcaa gaatatccat tgatcgctgc ataattactt ttttctgttc tttatttcgc
     1741 tggtttaata gcgcatggtg gaattttttg acttgtgaat caattgtagt ttgtattctt
     1801 tctttggtat aaggtgcaag aaaagcacgt tgtttcttta tttcattttc tatgtcttgt
     1861 aacgttttag aacgataatt cttgttggta gtctgctcct ctttcaacgt gttggtcatg
     1921 gtttcttcga gtcggtctaa tttccggttg ttcagtcgta agagttcgtt gttctcttcg
     1981 tacttctttt gcagtttcgc gaatgctagc tcgagctctt cgtagctcgt tggttcgttg
     2041 ttgattgtag gctcgttctc gtctgtccag ctcatgtaaa atcgtctcct tttcgtaatc
     2101 ctttcctagt ttgttggatc gtactttttt ctttttgtgg atcaattcgt aagtaaaatt
     2161 tttcccacga ttcaagcaat gaatgccgaa tgttttaaga gaatcacaaa attggttata
     2221 cgttcgagtt tttttgtttt tcattgtttg atcaatcgca aaccgaattt cgtctttcca
     2281 aacaggttca tttttttctt ttaatttgat ttcagacatg gttcgttttt cgggtttctt
     2341 ccctcgttca gtgattgtta agtcatgttc aagacaaatc tcgtcattta ggtcataaca
     2401 tttgtttaaa aatgcttgac catgggcttg aaatttgttc ccagtttcca gattgacgga
     2461 gttaatgaca atgtggttat gaatatggtc tttgtctgta tgtgtgtaaa tcgcgatttg
     2521 gtggtcaggg gctatttttt tcgcatactc tgcccctagt tgattggctt tttcagcggt
     2581 aatttctcct ggtcgaaaag actggatcaa taagtgtgct tgtacacgat cgtcttttcc
     2641 atacagcatg cgaatttgtt tcatttcgct tttggcataa tcaatgtcac agtttatccc
     2701 tgttttgacg gttgctcgtg gttcggcgta attgatcgct cggctacaag aagtggttcg
     2761 gcttacttta actgttgcca tatcttttgt agctcctttt gcatgatttt taggttttcg
     2821 gataagcgtt gggcgtcgcc aggatcaacg tcgtgttggt gtgtgttgca ccacttggca
     2881 atttgattga tattcccgcc agctttggct aaatcgcgcg cgattgcctg agcaatgtct
     2941 ggcgccactt tcggtgtcac cagacgcgcg ttttgtgcct tggctttcac gaaagccggc
     3001 acactcattt gcaaagcttc agctgactgc ttcagctttg caaattcgga ttcgctcact
     3061 cgaaaactga tttgttttgg ctcggatcga taggtatatt ttttagaatg attgctagcc
     3121 aaatattgat tttgttcgct cataagtccc accctttcag tacgtcctac ggacgtatcg
     3181 ttcgcaatac cattgtacct aaaaaggtac aataagtaaa gctcactaaa gctcactaaa
     3241 gggcttggca agctctatat ttgctagcca aatacctacg tatttggtgc aaataaccgc
     3301 ttgtcaaagg ggcgcaagct cccccttgaa tccccctccc ccccactctc cacaatacaa
     3361 aaaagactag caaatgctag ccactttttg taaagtttcg cttgtttcac cttcggtgaa
     3421 attgttgcaa atcaataatt aggtagagct acattttttt cgttgttcaa agattcttat
     3481 gccatttact attaataaat ctataaatat gataattttt cggctctata atttatggga
     3541 ctgatgaatc agaattgatt cttcagtccc attttcattt tattccaaag aattaactcc
     3601 aaataccaat agaagcccat cctctatata cttgagattc cttactaaca atttcttgta
     3661 attctattaa agatttaggt aatccaaatt tatgttttaa aatatatctt ccaagaaaac
     3721 tacttaattt catactaact tcaccaacac tttttccctc actgatttct ttagaataaa
     3781 gaaagagctt ttcttttaag tcaggatagt catctatagt tgcttcattg tatactttac
     3841 taattgcatt taaaagtttt tcttctttag taaaatccat tataataacc tccctaccac
     3901 taccttctag gtgcccatgg accatgatta acccaaccat taacaataat ttttccaatt
     3961 tctcctttag cttgattcca atctacccaa catttttctt tgttacaata aagaccattt
     4021 ccatagtaag tagctgcatc aacttttatt cctgtaccga tgccagctag acaagttcct
     4081 aatattccta gaataacaca atgttttaat actttctttt tcatgattgt ttttcctttt
     4141 cgttttttta aaattgcttg ttatattaaa taatcttagt aattttatta tataacattt
     4201 tattatataa caatgattaa cgtcataaaa agtagttttg aattcataat cgtttaaata
     4261 aaattataag atcagttatt taaacagcta gtagacataa tgtgtatact accaagtaac
     4321 gcctgtacca agggatccag gcgctgattt tgtgaatttt tattggtcta ggttaaaagc
     4381 tctttttaag gcttggtttt ctgcggttgt ttctttctaa ttctttgtga atattgatcg
     4441 gtcatttttt aaatacttgt tatttttgtt tgtgtttgtt atgcttttta catatctcat
     4501 attcatttat tattcttttc taaggttaat aataggataa tctctttcag aaagactgct
     4561 cgtacgagca gtcttttctt atttatcaag tttttctaca aatacttcct cattttgact
     4621 gttgtagtaa ttaggattga gttttagttc ccctttttta tttcctttgt tggccactga
     4681 taataacatt gggctaaagc ttaatattcc tagtaggata gaaccgaata gcaagtgttt
     4741 ttttgtcata agtatttcct tcttcatttc catagctgcc accatttttt ccaattcttt
     4801 gtttgttcgt ccattgtttc tgttgcttca gaaagagtcg ttgaactatt ctctgaagac
     4861 tcttccgtat aagtcaactg cagttgctcc tgaagttttt cgatttgttg gttggcttgc
     4921 agggtgagtt gttgttgctg gtcgagtagt ttttgtatat gagaattatt ttgctctttg
     4981 agggcaagtt gttctcgtaa aaattcattt tcttcacgca actgatctag caacttgttt
     5041 gcaaccacgt ttttgtttgg tatataagca tttttatcgt tgttttgttc atgtttatgc
     5101 aacttatcta gcaacctttg attgtctaag ttgcgagcaa gttgcaatac tccagaacgc
     5161 aatacaacct tataaccacg ctcattttta gctatcatgg aagaatctaa tttttggata
     5221 tgtttcgata ttgcttgcct actcatctta aaaagatctg acaattcctt tattgtaaag
     5281 gtttcttgtg gttgcatact ggttgcctcc taggttgcta ctggaataaa ttatctaaat
     5341 cagataataa actttttttc tctttttccg aaagtgcgga ctctgtttgt ttttcaagag
     5401 cttttttctc tttttctagt tgtttgattt gttggaggag ttcaagttct cgtttcttct
     5461 gtttgatttt ttcgttaatt gttgtagcgg gttcttcgta ttctttttgt ttatcagcta
     5521 aagccaatgc tttattttgg tcttctttgg ttggtgcatg tttgttaaag tcgtctgctt
     5581 ttttgatctc aggtttgaac gtaaattgat agccaataac aggttttccc cgtccttttc
     5641 cgtatttctt tttgattgtt agtcctttga agattgcagt tagttcttga cgtataggtt
     5701 ttataactcg tttatctata tcaggttgct tataactttt aggaatatct aataattcaa
     5761 gaaagtcttc tttggagaaa tatgcgaaac ctttggttct gtattgcttt aacagacgaa
     5821 acatagtctt tgcatagcca ctttgtagct cgttgaattg ttgtaaagaa tagcgtaccc
     5881 actcgtctaa attatttaac aaaggcagtg ctttttcgta aattcgtata tctacgtaag
     5941 gattttctac gtccccgttg attttaaatt ctgtaaacat tacaaacata tcgtaagaaa
     6001 gcccagactc acttctacga ccaaagcgta aagataagat tttttcataa gttgctttta
     6061 aatcttctac aaatcgtaca tttgcagttg ctttgtagtt acttaaatct tttagttggt
     6121 caaacgtaaa acgaactgtc ttatcccctt tttcacgcat tctagacacg atgg
//
LOCUS       DAZUJR010000118         6154 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.122, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000118 DAZUJR010000000
VERSION     DAZUJR010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6154
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.122"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(137..1099)
                     /locus_tag="ACG804_002654"
     CDS             complement(137..1099)
                     /locus_tag="ACG804_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4833528.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1101..2540)
                     /locus_tag="ACG804_002655"
     CDS             complement(1101..2540)
                     /locus_tag="ACG804_002655"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004564 - beta-fructofuranosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HFS4833529.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2725..4671
                     /locus_tag="ACG804_002656"
     CDS             2725..4671
                     /locus_tag="ACG804_002656"
                     /EC_number="2.7.1.211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-specific PTS transporter subunit IIBC"
                     /protein_id="HFS4833530.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            4935..5807
                     /gene="scrK"
                     /locus_tag="ACG804_002657"
     CDS             4935..5807
                     /gene="scrK"
                     /locus_tag="ACG804_002657"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HFS4833531.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIENRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT         1958 a         1051 c         1093 g         2052 t
ORIGIN      
        1 atttctccac tccaaaaaag tctaactttt gggggtcact acaagttgac aactcctttt
       61 tgtttacaaa tcaattggat atctacaaat tgtattttct aacgaatttt atagacatta
      121 aaaaattaat ttaacgttaa atacttcctc cagaaagtat tgagattggt aaaatataat
      181 ccttatttgt cttttcgcct ttaatttttt tcagaagaat atcaacaata agacttgcaa
      241 tttcatcaat tggttgtctt attgttgtca attgtgggaa aaatttctca atgaaagagg
      301 taccatcgta tccaataatt tttaaatctt ctgggatatt aagtttaagt tgatgagcaa
      361 ttttcatagt gagaatggct gttaaatcat cagaaacaaa aataccatct ggtttgtgat
      421 ttataatagt tgactttatt tccatttcac gacggatagt agacagatta ttaggaattt
      481 tgaaaatttt tccatttgga ttttgaaaag aaaaacctag tgcacgtaat tctgtgggag
      541 aatccgtgtt atcatttcct gtaatcataa tggtattttg acaaccattt ttttgtaaag
      601 tcttagctgc aagttttccc ccttcaaagt tatctgaaga aacaatggaa acattaggag
      661 ctaaatttct atcaaaagca acaataggtg ctctcacacg ctcataatca gcaattccaa
      721 gattatggct tgatgagatt atgccatcaa cttggttggc ttcaagcatt tcaatgtatt
      781 ctctctcttt agcaggatca ttttgactat tgcaaataat cgttttatat ccatgtttaa
      841 ataactctat ttcgagatac tcaatgagtt cagagtaaaa gatattacta atattaggaa
      901 aaataagacc aataagctga ggtgactttc cttgaagtcc acgtgctaaa ttatttggtt
      961 tataaccaag agttttcata gcttcatgaa ctttttgttt tgttttttct gataaatatc
     1021 ccttattatt aatgacgcgt gaaacggttg ttgggctaac tccagctaat tcagcgacat
     1081 cagttaattt tgctaccatt ttaatatttt aattcaaagt attttccagt aggttcgcct
     1141 gatttgattt gaataccatt ttggtgattt tcagggaata cacgactagt aaacactttt
     1201 tctcctttat taataaaaat ctcaatgatt gagttatcta caaaaatgtt agcagttgtt
     1261 tctttagtat caattgagca ttcacgaatc gtaccaaagt cagtggcata ttgaatgcct
     1321 gctttgctgc gatctaaaat aatttttcct tctttggtat ctacaatcaa gctaagtcca
     1381 tttcctttac tatcagagaa aagaagtaac tccgatttct gatttggagg aaaagttagt
     1441 tcaagctcat aagtattatt tgtttctgct tttgctgtaa attgttcaga actagcacgt
     1501 aatgatgtaa tagcttctac tggatattgg taaagtttac catcttttat tgaaagttct
     1561 tttacaagac tcattgctcc ctgataatca tacttatcag ttggataatc gatatcaggt
     1621 agtccaatcc aactgacaat cagagcacga ccatcaggag tattgaatcc ttgagtcgca
     1681 tacgcttcaa atccataatc aagattttga atttctgaag cgcccacaag ttttactttt
     1741 tctatgtcaa gcgattgaca gatcttaaaa gtattcggat agatattccc ataatttagc
     1801 tcagatttat ccaacccttg aggacaataa atgagaacag gttttttgtc tacaaatact
     1861 agatttggac actcaatcat gtattctgaa ccagtgccgc caaaatcaag gttgccaact
     1921 tcctcccatg tttccacgtt attgtcatcc gctttgtaaa gtttgataaa gcctgatttt
     1981 tctaaatttt gtgctccaac aatcgcatac aattgtcctt cataattaaa catttgtgga
     2041 tcacgaaaat gatcagttac atcagcaggt ttatgaataa gaacattctc acctttcgta
     2101 atgttgtagt ctttatccat ccatgctccg atttgaagtg tatcacgttc ccaattttca
     2161 tttcgaacgt ttcctgtata gagtaagaat agattcccct ctatttcata tgcagaaccg
     2221 gaataagcgc cgtggctatc tcgttttgtg tctggaagaa gttctgctcc tgttacatga
     2281 aaatgaacta aatcatctga ttcattgtgt acccattctt tcaacccatg agcagctcca
     2341 aatggccaat tttgataaaa aagcgtatat tttccgttaa aaaaagaaaa accattagga
     2401 tcgtttaaca atcctgtttt aggttcgata tgatagctag cacgccaagg tgatcgtttt
     2461 acattatcct taattttatc catctcatct ttagtccaat cagaataagc acgatatcgt
     2521 atttctcgag gtaagttcat attttactcc ttcaatttat ctttttacaa ctagtatggt
     2581 aaacgttttc cgttgaaaaa tcaatcattt catttaaaaa aataaactat atgacaaacg
     2641 tttgacatat ttttaagata tgctaaaata aatttgcatt tcagtgaacc gttttcacgt
     2701 aaaaataaaa aaggagtgat tcgaatgaat tacagtaaag tagcttccga cgtaatacaa
     2761 gcggtcggaa aagataacct tattgcagct gcacactgcg ctacacgtct tcgtctcgta
     2821 ctaaaagatg acacgaaagt gaatcaaaaa gctttagacg aaaatccaga tgtgaaaagc
     2881 acatttaaaa ttgatggaca atatcaagtg attatcggtg caggtgatgt taatttcgtt
     2941 tatgacgaac ttatcaaaaa aactggactt tcggaaattt caacagatga tttaaaacaa
     3001 attgctagta aagataaaaa attcaacccc attatggcat taattaaatt attatcagat
     3061 atttttgttc caattatacc tgcccttgtt gcaggtggtt tattaatggc attacaaaac
     3121 tttttaacag ctgctggact ttttggacca aaatcaattg aagaaatgta tcctgcgatt
     3181 gaaggtattt cctcaatgat ccaactgatg tccgctgcac cattcatgtt cttaccaatt
     3241 ttagtaggta tttcagctgc taaacgtttt ggagcaaacc aatttcttgg tgctgcaatt
     3301 ggtatgatca tgacaacacc agatcttggt ggctcaactg aatattggaa tatttttggt
     3361 tatcatgttt cacaaacaaa ctatgcttat caagttattc cagttttagc agctgtttgg
     3421 atattatcta tattagaaaa attctttcat aaaaaattgc catcatctat tgactttaca
     3481 ttcacgccat tattatcagt aatgattact ggatttttga ctttcacagt tattggccct
     3541 gtaatgttat tgttgtctaa tggaattaca gacattattg tttggctata taacactact
     3601 ggatttattg gaatgggtat ttttggagga acatattcac ttatagtcat gactggttta
     3661 catcaatcat ttccagctat tgaaactcaa ttactttcag cgtggacaaa tggtatcgga
     3721 catggagact ttatctttgt agttgcatct atggcaaacg ttgctcaagg tgctgcaaca
     3781 tttgccattt ggttcttaac taaaaattct aagacaaaaa gtcttgcttc ctctgcgggt
     3841 gtctcagcac ttcttggaat tacagagcct gccttgttcg gagttaactt aaaataccgc
     3901 tttccattct tttgtgcttt aattggttca ggaattgcta cagcagtagc aggattactt
     3961 aaagtagttg ctgtttcact tggttcagca ggtttcttgg gatttctttc aattaatgca
     4021 acatctattc cattttacgt attgtgtgaa ttgattagct ttgtagttgc ttttgcaatt
     4081 acttacttct acggtaaaac aaaagctgct ggtatcttta aagcagaaga aattgctgaa
     4141 caaacaccag ttaattcttc aaaagtagca acaacagatc caatatctac tgatgttgaa
     4201 tcaacacaaa caaaagtttc atcagaaaca attgttagtc ccatttctgg taaagtgatt
     4261 agtctttctt cagtaaatga tccagtcttt tcatcagaag ctatgggaaa agggattgcc
     4321 attaaaccaa atggaaacac ggtccattct ccagtagatg gtactattca actcacgttt
     4381 gaaactggac atgcttatgg tattaaatca aataatggtg ctgaagttct aattcatatt
     4441 ggtattgata ctgtatcaat gggaggaaaa ggatttacac aaaaagttac tactaatcaa
     4501 aaagttagaa aaggcgatat tcttggagca tttgaccgtt caatgattga gaaagaaggt
     4561 cttgatgata caacaatgat tattgtgacc aatacttcgg attattcaga agtaaatata
     4621 gtagctgaaa atacagtcac tgagggtact gatttacttg aaatcaaata aatatatttc
     4681 cctgagtaaa gatggaattt tctttccaaa atcaaataat atagattaat caaatatttg
     4741 agaataacat tttatttaat cttttcatat atcaattgta tgaaaaatta ttagaatttt
     4801 aaaaaatgat aaaaattcaa aaagaaaaaa tagtagttat ttacttgtca tgttactaaa
     4861 taaaaaaata atttaaatat gatatatagt catttattta gtgatttcat tctaaaataa
     4921 agggagaaat gtctatgcta tacggtgcaa ttgaagcagg cggcacaaaa tttgtgtgtg
     4981 ccattggcga tgaagaaatg acgatcaagg aaagagtgag ctttccgaca acgacacctg
     5041 aggaaacaat gcctttagtc attgacttct tcaaacaata ccaagcagat ttagcaggga
     5101 ttgggattgg ctcatttggg cctatcgata tccatcgcga ttccgccact tatgggtaca
     5161 ttacctcgac cccgaaattg gcatggcaaa attttgattt catcggtacc atgaaaaaag
     5221 aatttccgat cccgatttct tggacaacag atgtcaatgc ggctgcctat ggtgagtatg
     5281 tcttcggcag tggcaaagga ttgagcagtg tcgtttacta tacgatcggt acgggtgttg
     5341 gcggcggtgc cttacaagaa gggcgcttta tcgaagggtt tagtcatcca gaaatggggc
     5401 atatgctcgt cgtccctcat ccaaaagatg actttgctgg cagctgtcca tttcatggca
     5461 actgtttaga agggatggcc gctggacccg ccatcgaaaa ccgcttaggg aaaaaaggac
     5521 aagaggttgc agaagatgat ccttattggg aaatcgaagc ctcctatatt gctcaatgtg
     5581 cctacaatac aaccttgatg ttttctccag atgtgatcat ttttggcggt ggtgtgatga
     5641 aacaacgcca tatgctgcaa aacgtccacg acgcatttgc aaaattggtc aatgggtatg
     5701 tcgaaacacc tgagttaagc aaatatatcg tgaccccagc attagaagac aacgctggaa
     5761 cgctcggttg tttggcattg gctcgagaag cggtcttaca ttcataaacg aaaaaaggct
     5821 cttcgacatt tagtgttggt agagaaagat acaactgaaa atttagtcat aaccagttag
     5881 gcagagtgct taactggttt ttgttttact tggaagatca agccttgaat gagataaatt
     5941 cttgctcgaa agttatggaa atttcgatag ccgtaggcca cttgtattgt gcaatagttt
     6001 tttacaaaaa aaagggggtg cggatatttt tttggacctt tttaacaaat aggttctgtt
     6061 gcaaagtttt aaatctacta tcagataagg tagaataata gaaaaagata gcaggaggaa
     6121 tgacgatgag tcattttaaa ggaaagcaat ttca
//
LOCUS       DAZUJR010000119         6068 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.123, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000119 DAZUJR010000000
VERSION     DAZUJR010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6068
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.123"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            832..1566
                     /locus_tag="ACG804_002658"
     CDS             832..1566
                     /locus_tag="ACG804_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFS4833532.1"
                     /translation="MQNTFQSKSLYYQLVEILKQRIENSMVAHDKLPSERELTSFYGV
                     SRTTVRLALQELEKMGYIYRQHGKGTFVSELRTNATDLAGAYSFTEQMRAMGKHPETK
                     ILAFKKIEATKYLASHLNVQLGEPLFQLDRLRLADDLPMMIEKSYLPVKLFMSLSQEI
                     LFLKPLYNLFSENFNQIVRLADEEFYASIVQKEDSELLNIPEGSPVLHLVRSTYNLEN
                     EVIEFTLSVARADKFHYKIRHLRSTN"
     gene            1582..2751
                     /locus_tag="ACG804_002659"
     CDS             1582..2751
                     /locus_tag="ACG804_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFS4833533.1"
                     /translation="MFMFSKEELRKLGAENTTREIRQQPELWHETFDRYQETVADLDR
                     LFTDAKQHAGERPIRVIFTGAGTSQYVGDTLIPFLTSQGNTNQFIFQSIGSTDIVATP
                     KEYLIPDETTILVSFARSGNSPESLAAVKMANQLVNKIYHIVITCAPDGLLATQMPTK
                     KENLVLLMPNKANDAGFAMTSSFSCMTLTALLIFDQASNQQKERYVHQLSRLGEEVIQ
                     RESEIQGYLASDFHRIIYLGSGSLGGLTREAQLKVLELTAGKIATVFDTSLGFRHGPK
                     SFVNEQTLVFLFVSNDSYTQKYDVDMLEEIKNDGIAQRVVGIGQKGSLFSGDSFELVA
                     DSLLPDGYLALADIMVAQTIALLCSVKVGNTPDTPSPSGTVNRVVKGVTIYPYEK"
     gene            2767..3762
                     /gene="lacD"
                     /locus_tag="ACG804_002660"
     CDS             2767..3762
                     /gene="lacD"
                     /locus_tag="ACG804_002660"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HFS4833534.1"
                     /translation="MLEWSENKRQAMERLSTPEGIITALAIDQRGALKKMMSALGMEA
                     TKEKIEQFKTLISQELTPYASAILLDPEYGLPAAQKRAAASGLLLAYEKTGYDQTVPG
                     RLPDLLSDCSVLRLKELGADAVKFLLYYDYEEAEEINRQKQVFVERIGSECMAEGLPF
                     YLELLSYDAKNVDTKSLSYAKAKPRKVIEMMKEFSKTQYKVDVLKVEVPVNMSFVEGN
                     ATGEIAYTRQEAAAYFKEQSDATDLPYIFLSAGVSAALFMETLRFAKHAGARFNGVLC
                     GRATWKDAVAPFVEKGEAATLEWLTEQGTQNIRQLNEVIRETAIPWYEKVSESTC"
     gene            3841..4767
                     /locus_tag="ACG804_002661"
     CDS             3841..4767
                     /locus_tag="ACG804_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HFS4833535.1"
                     /translation="MNKRLLDYSASDFLKAKPMELKQAILASEGRTIMAENVPSSCPY
                     MGKSVTNAELERAAGADLILFNALDLFNPQISGVPLTLKENPIIWIKKALGRAIGVNL
                     EPVDKEVLMSENRTEISSGRIVSPETLKKANELGFNFICLTGNPGTGVSNRTIEKAIT
                     LSKSIFNGLIIAGKMHGAGVDEPIMNLDIAKRFIKTGVDILLVPAPYTVPYFMESDLR
                     GIVDYIKDFNRNKSIEEKVLVLTANGTSQDSSDQETIKKIALASKACGADIQHIGDSL
                     NGICLPENIFALGQAIRGYRHQIIMLGKSNYR"
     gene            4786..6036
                     /locus_tag="ACG804_002662"
     CDS             4786..6036
                     /locus_tag="ACG804_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFS4833536.1"
                     /translation="MIDKVQKIAAKISNQRHLLALRDSMAAVMPLIIIGSFFMLLANF
                     PIEGFTKWLSEIGVQSFLNKASDSTFGIIGLAVTYSLGHNLAKTYGVDSLSAGLLSLS
                     GYVLLTPLLDADGSIGFPTKYFGTSGLFVGIIVALVSTEIFRWFVLKNITIKMPASVP
                     PNVSRAFVAIIPGFFVVLLWFIVVVICYKLGIENVHALIADTLAKPLSLLTKTLPGII
                     LVILIQCFFWMFGIHGAQVTGPIIEPLLLQNSDVNRIAYQAGKELPNIITYEFLYNFV
                     FSGGAGCLFALAILTFFFSKSQENKTLGKLSIAPVSFQVAEPLLFGFPTILNIKMLIP
                     FVTAPVVTTLITYFSMSMGLVAKPVGATIPWTTPPIIAGFLASGGRISGAVIQVITIA
                     INVLIYYPFFKLDDNAKLKSEKND"
BASE COUNT         2027 a          997 c         1246 g         1798 t
ORIGIN      
        1 attggcgcag cgaatccttg ataatgagct cggatgtgct aacgctagcg aggcagtcta
       61 actttaactg ttagctcctg ccgaagatcg tcacatccga ggaggctcat tgtcaaggac
      121 aatcggaata gcatacggaa agaagttctg caccttataa aatttgtcaa aaaaactgtt
      181 gccattccaa agtttgaaaa atgctatttc gaggtagaag gatattatat aagcacggtt
      241 gactaaacga agtgataata aaaaaagtta ttcaagaata agaaaaatta tgatacgaat
      301 tcagataaac tggagaatac agagaccttt aaaagggata agaaacaaca taaattcctc
      361 ttaagagaga acgaaaggac aaagccagca acttgataca cgagctagta ttagaggaat
      421 ttattctcat agactccctt ttgaatacgt ttcaacttta attttcatgt tcataaatga
      481 tttgaaacca aagcaaatgc gttgcacttt tcctccgtct tccgaaaatc gttcaattca
      541 ctggtaagta gtcatttgat agtttgaggc aaattgttga ttgatgaagg gtaggagcta
      601 aaaaaagata ccagttgaag agagaaaaag aaaaaaatag agggtgttct tgaatgaaaa
      661 aagttggaaa attatttttc atttcctttt attcctatta aagtcagtga tgtcaatcat
      721 attaacaaga ctaaaaatga aaataaaaaa aagattgttc ttagtattga ctcataaaaa
      781 ataccactac tatacttaca ttgtggttat agccagttag gagagacatc gatgcaaaat
      841 acctttcaat caaaatcact ttattatcag ctggtagaaa tattgaaaca acgaatcgaa
      901 aacagtatgg tcgctcatga caagctgcca tcagaaagag agttgaccag tttttatggc
      961 gttagtcgca cgacggtgcg actagcattg caagaactgg aaaaaatggg ctacatttat
     1021 cgacaacatg gaaaaggaac ctttgtttcg gaattaagga caaatgcgac tgatctagct
     1081 ggcgcatata gttttaccga acaaatgcgg gcaatgggca aacatcctga aaccaagata
     1141 ttggccttca agaagattga agcaactaaa tatttagcga gtcatctgaa tgttcaacta
     1201 ggtgagcctt tatttcaatt agaccgattg cgcttagctg atgatttgcc aatgatgatc
     1261 gagaaatcct atttgccagt gaagctattt atgtcccttt ctcaagaaat tctatttctg
     1321 aaacctttat ataatttgtt ttcagagaat ttcaatcaaa tcgtacggtt ggctgacgag
     1381 gaattttatg ccagcattgt ccagaaagaa gatagtgagt tgctaaatat tccagaagga
     1441 tcaccagtgc tccatttagt tcgctcaacc tataatctcg agaacgaagt gattgaattt
     1501 acattaagtg tagcgcgggc tgataaattt cattataaga tcaggcatct gcgttccact
     1561 aactgaattg gaggaaagaa aatgtttatg ttctcaaaag aagaactacg aaagctagga
     1621 gcagaaaata ctacccgaga aattcgacaa caaccggaac tgtggcatga gacgtttgac
     1681 cgttatcaag aaacagttgc agatttagat cgtttgttta cggatgcgaa acaacatgct
     1741 ggagagcgac caatccgagt catttttaca ggggccggaa cctcgcaata tgtgggagat
     1801 acactaattc cgtttcttac tagtcaagga aatacgaacc agtttatttt tcaaagtatt
     1861 ggttcgaccg atatcgttgc tacgccaaaa gaatacctga ttcctgatga gacaacgatc
     1921 ttggtctcat ttgcccgtag tggaaatagt ccagaaagtc tagccgcagt taagatggcc
     1981 aatcagctgg tcaacaagat ctatcatatc gtgatcacct gtgcaccaga cggattattg
     2041 gctacacaaa tgcctacaaa aaaagaaaat ctagttttac taatgccaaa caaagccaat
     2101 gacgctggtt ttgctatgac aagcagtttc agctgtatga cgctgactgc gctacttatt
     2161 tttgatcaag caagcaatca gcaaaaagaa agatatgttc atcaattaag ccgactagga
     2221 gaagaagtca tccaacgaga atcagagatc caagggtatc tggcatcaga ctttcatcgc
     2281 atcatttact taggttcggg aagcttaggc ggattgacta gagaagcgca attaaaagtt
     2341 ctcgagttaa ctgctggaaa aatcgcaacc gtatttgata catctttagg attcagacat
     2401 ggtcccaaat cttttgtcaa tgagcaaaca ttggttttcc tgtttgtcag caatgactca
     2461 tatacgcaga aatacgatgt agacatgctg gaagaaatca aaaatgacgg tattgcccaa
     2521 cgcgttgttg gaattggtca aaagggttca ttgtttagtg gtgattcctt tgaattagtt
     2581 gcagattcgt tactgccgga tggctatctt gctttagcag atatcatggt agcccaaacg
     2641 atcgcattac tttgttcggt gaaggttggt aatacaccag atacaccatc gccaagtgga
     2701 acagtcaatc gtgtggtcaa aggcgtaacg atttatccat atgaaaaata ggaaagagtg
     2761 tgaagcatgt tagaatggtc ggaaaataaa agacaagcaa tggaacgtct atcgacgcca
     2821 gaaggcatta ttaccgcttt ggcgatcgat cagcgaggcg cgctgaagaa aatgatgtcg
     2881 gctttaggga tggaagcgac aaaggaaaaa attgagcagt ttaaaacact aatttcccaa
     2941 gaattgactc cttatgcctc agcaatttta ttggatcctg aatacggact gcctgctgca
     3001 cagaagcgtg cagcagcgag cggtctgctg ttggcatatg aaaaaactgg ttatgatcaa
     3061 accgtacccg gccgcttgcc ggatctgctg tcggactgtt cagttctgcg attgaaagag
     3121 ttaggtgcgg atgcggtgaa atttttactg tattacgatt atgaagaagc agaggaaatc
     3181 aatcggcaaa agcaagtttt tgttgaacga attggaagcg aatgcatggc tgaaggactg
     3241 ccattttatt tagagttatt gtcatatgat gctaaaaatg tagatacgaa atcgctttcc
     3301 tatgccaaag caaaaccgcg caaagtgatc gaaatgatga aagaattctc gaaaacccag
     3361 tataaagtag atgtcttaaa ggttgaagta ccagtaaaca tgtcatttgt tgaaggaaat
     3421 gcaacagggg agatcgccta tacacgtcaa gaagctgccg cttattttaa agaacaaagc
     3481 gatgcaacag atttgccgta tatcttctta agtgctgggg tatcagcggc attattcatg
     3541 gagacattgc gttttgccaa acatgctggg gcacgattca acggtgtact ctgtggcaga
     3601 gcaacttgga aagatgcagt cgctcctttc gttgaaaaag gagaagcggc aactttagaa
     3661 tggctgacag aacaagggac acaaaacatt cgtcaattga atgaagtgat aagagaaact
     3721 gccatcccat ggtatgagaa agtaagtgaa agcacttgtt aatgtttcta atatattagt
     3781 agtgataaga gatatgtgtg attataattt atcattattg aaactgggag gatattttat
     3841 atgaataaaa gattgttaga ttattcagct tcagattttt tgaaagctaa gccgatggaa
     3901 ttaaagcagg caattttggc ttctgaaggt agaacaatta tggcagaaaa tgtgccaagt
     3961 agctgtcctt acatgggaaa atcagtgaca aatgcagaat tggagagagc tgctggagct
     4021 gatttaattt tgtttaatgc actagatctt tttaatcctc aaatttcagg tgtaccttta
     4081 actctaaaag agaatccaat aatctggatt aaaaaagctt taggaagagc tattggtgta
     4141 aatttagaac ctgtagacaa agaagttttg atgagtgaaa atcgaactga aatttcaagt
     4201 ggtagaatcg tttctcctga gactttaaaa aaggcaaatg aattaggctt taattttatt
     4261 tgtttaactg gaaatccagg aacaggagta tctaatagaa ctattgagaa agcaataaca
     4321 ttatccaaat caatttttaa tggattaatt atcgctggaa aaatgcatgg tgctggtgtt
     4381 gatgaaccaa ttatgaactt agatatagca aaaagattta ttaaaacagg tgtagatatt
     4441 ttattagttc ctgctccata cactgttccg tatttcatgg aaagtgattt gcgaggaatc
     4501 gttgattata taaaagattt taatagaaat aaatctattg aggaaaaagt tctagtacta
     4561 acggctaatg gaacaagcca agactcttct gaccaagaaa ctattaaaaa aattgcatta
     4621 gcatcaaaag catgtggagc tgatattcaa cacatagggg attctttaaa tggtatttgt
     4681 cttccagaaa atatttttgc tttgggtcaa gcaattcggg gatatcgtca tcaaattatt
     4741 atgttaggaa aatctaatta tcgttaatta aggaggaaat gaaagatgat cgacaaagtt
     4801 caaaaaatag ctgcaaaaat tagtaatcaa agacatctac tagctttaag agacagcatg
     4861 gctgcagtta tgccattaat cattattggt tcctttttta tgttattagc aaatttcccg
     4921 atagaaggat ttacaaaatg gttatctgaa attggagtac aatccttttt gaacaaagca
     4981 tcagattcaa catttggtat tattggatta gctgttacct actctttggg acacaatcta
     5041 gcaaagactt atggtgtaga ctcattatca gcaggattat tatctttgag tggatatgtt
     5101 ttacttacac ctttattgga tgcagatggt tctataggat ttccaacaaa atactttggt
     5161 acctcgggtc tttttgttgg tattattgta gcacttgtat ctacagaaat tttccggtgg
     5221 tttgtactta aaaatattac aattaaaatg ccggcaagcg ttccaccaaa tgtaagccga
     5281 gctttcgttg ctattattcc tggctttttt gtcgttctac tatggtttat tgttgttgta
     5341 atttgttata aacttggaat tgaaaatgtt catgctctta ttgcagatac actcgcaaaa
     5401 ccactatctt tactgacgaa aactttacca ggaattatat tggttatact tattcaatgt
     5461 ttcttttgga tgtttggtat tcatggtgca caggtaacgg ggccaataat tgaaccgtta
     5521 ttattgcaaa actctgatgt aaatagaatt gcttatcaag ctggaaaaga acttcctaac
     5581 attataactt atgaattctt atataacttt gttttttctg gtggtgcagg ttgtttattt
     5641 gcacttgcca ttttaacatt tttcttttca aagagtcagg aaaataaaac tttaggtaag
     5701 ttatcaatcg ctccagtaag ttttcaagta gcagagcccc ttctatttgg gtttccaact
     5761 atattaaata taaaaatgtt aattccattt gtaactgcac cagtagtaac aacattaatt
     5821 acttattttt caatgagtat gggattagtt gcaaaacctg taggagcaac aatcccatgg
     5881 acaactccac cgataattgc cggattttta gcttctggtg gacgaataag tggtgcagtg
     5941 attcaagtaa taacaattgc aataaatgtt ttgatatact atccattctt taaattagat
     6001 gataatgcca agctaaaaag cgaaaaaaat gattagaact acctatatgt ttctaactgt
     6061 agttaagt
//
LOCUS       DAZUJR010000120         5808 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.124, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000120 DAZUJR010000000
VERSION     DAZUJR010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5808
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.124"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(49..2220)
                     /gene="copB"
                     /locus_tag="ACG804_002663"
     CDS             complement(49..2220)
                     /gene="copB"
                     /locus_tag="ACG804_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HFS4833537.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIR"
     gene            complement(2240..4426)
                     /locus_tag="ACG804_002664"
     CDS             complement(2240..4426)
                     /locus_tag="ACG804_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFS4833538.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGLIAVADQIKLEVKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLCLNRHMKK"
     gene            complement(4426..4635)
                     /gene="copZ"
                     /locus_tag="ACG804_002665"
     CDS             complement(4426..4635)
                     /gene="copZ"
                     /locus_tag="ACG804_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HFS4833539.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(4648..5088)
                     /locus_tag="ACG804_002666"
     CDS             complement(4648..5088)
                     /locus_tag="ACG804_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HFS4833540.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYYPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(5162..5701)
                     /locus_tag="ACG804_002667"
     CDS             complement(5162..5701)
                     /locus_tag="ACG804_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFS4833541.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQLFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
BASE COUNT         1503 a         1305 c         1015 g         1985 t
ORIGIN      
        1 tcgaaaaaaa ggttgtgaca cgttttttgt cacaaccttt tttcattatt atctgatttt
       61 caatgtcaaa gcatttagag ctacaactac cgtacttaac gacatcaaga cagcaccaac
      121 tgctggactt aatatgatac caattggcgc aagaattccg gctgctagcg gaattgcaag
      181 aatattgtaa cctgcccccc accagaggtt ctggatcatt ttctttcgcg tttgcttggc
      241 tagatcaaga aaatgcaaaa tatcttttgg atcgctgttt gtcaatacga catccgcaga
      301 atcgattgcg atatctgtcc ctgcaccgat tgccatcccg attgaagcac gggctaaact
      361 tggcgcatca ttgatcccat cacccaccat gattactttt ttcccttggt caaggtattt
      421 ctggacaaca gcttctttat catctggtaa taaaccgcca taatattctt cgatccctaa
      481 ataatctgct actgcttggg cagcgttttt attgtcacca gtaagcatga caggagtgat
      541 ttttctttct ttcaatgttc ggataaattc ttttgcttct gtttttacta cgtcacctaa
      601 agcaacgatt gcagctagat gattttctaa aatcaggaag ctgatggtat ttccttgttc
      661 ttggtaaggt ttcaataatg cttgttctac gtttaatccg agacgctcaa cttctttttc
      721 attaactatt ttcacttgtt gttttttgac tgttgcctct agcccgactc ctgaaagatt
      781 ttttagattt tcagcttgat aaggcttgat ttcatgttct ttcaaataat tcataatgcc
      841 aacagccaat ggatgattgg cattcgcttc caaggctcct agatattgaa ggatttcatt
      901 tttattgaac gcatcatcaa gtacttcgac acccgttaca gtaaattttc cttctgttag
      961 tgttcctgtt ttgtccagca tgatcacatc tagatcattg gcttgctcca gtgcattgcg
     1021 gtttttcaaa agtaatccgt ttttagctgc tattgatgtg gaacgagcaa caactaatgg
     1081 gatagctaaa cctagagcat gaggacaggc gatgataaag actgttacca tacgttctaa
     1141 tgcattagga agatctgtca agaacaacca ggcgatgaat gccaggatac ccacaattaa
     1201 tgcgacataa aacagccatt ttgccacttt gtcagataat gactctagct tggatttttc
     1261 tccttgtgct tttcgcacca tttccataac cttcgctaga taaccatttt caccagttcc
     1321 agttacttcg atttcgatcg ttccatcccc attgatagaa ccgccaatca ctttgtcatt
     1381 ggcttgtttt ttgattcctc ttgattcgcc agtcacagct gattcgtcaa caattgtttc
     1441 acctttcaag attacaccat ctgttggcat tttatcacca gaccggacga tcaaacgatc
     1501 accttcgttt acttctttca atgaaactgt ctcttctttt ccatctttcg tcaagcgttt
     1561 cactgattct ggcagtaatt ctgctagttt ttgtaaagca ttgctggcat tcgacacagc
     1621 attcatttca atccagtgac ctagtagcat aataacgatc aaagtagcca attcccagaa
     1681 gaaatccatg acgtgtgtat gtggattgag cagatttgcg ataaacgaat agacactata
     1741 aatatatgca actgtaatcc ccatcgcgat cagtgtcatc atagcaggac ttttttgttt
     1801 caattccatc ttagctccac ttaaaaatgg ctgaccgcca tagataaata gtatagttgc
     1861 taagatcaat acgagccaat cagaaccagg aaacgttact tgaaatggaa attccattcc
     1921 catcattggt gaaaaaagaa tgattgggat agctaggata agcgatagcc aaaatttttg
     1981 tttgaaattc cccatgtgca tggaatgatc catgccgccg tgttcgtgat ccatgtgcat
     2041 cgaatggtcc atttgtttgc tgtttgctat atctccatgg ttatgtccca tgtgcatgga
     2101 atgatccatc tgactatggt catgtttcat ctccatctgt ttttcatgag attctgtact
     2161 ttctttgttt actacttctt ttttatgctc atgttttttc tccatatcgt tcccattcat
     2221 ttttactcca tcccttctct tactttttca tgtgtcgatt taagcacagg gagttcaaca
     2281 atacactgac ggaactaaac gccatcgctc ctcctgcaat gattggattc aaaaagccta
     2341 gtgcggcaaa aggaatacca atcgtattat agacaaaagc ccagaaaaga ttttgtttga
     2401 tttttctcaa tgtcaaccta gacaactcga ttgtttgtgc aatggatgcc aaactgctat
     2461 tcatcagcgt cacatcggct gtttccatcg caatgtccgt tccacttccc attgccatac
     2521 cgacatcagc taatgctaag gccggtgcat cattgattcc atcgcctgcc ataccgactt
     2581 ttttgccatc tttctgaagt ttttctacgt aggctgcttt atcctctgga agtacttcag
     2641 caaagatatg ctttggatca ataccaactt gtttaccaat cgtttcggct gccagtttgt
     2701 tgtctcctgt cagcataaaa acatctaatc ctttattctg gagctgcttg attgcttgtt
     2761 tgacttctag tttgatttga tcagccacgg caatcaaccc gatcacttgc ttttcatcag
     2821 ctaaaaacat gactgttttt ccctgctgtt ctaattctaa cgcgtgttct tggtattcat
     2881 caaatgatag gttcaattca attaatcgtt tacgtgtacc cgcaaaatag cgtactccgt
     2941 taatcgtacc gctgattcca gcacctgggt gggctgtaaa atcaatcata tcgtatgttg
     3001 ctgcttcttg cagttttccg tattccacga ttgctttacc tagtggatgt tcagaagctt
     3061 gttctaaagt ataaaaaata gataggactt ctttagaacc gactagatct gtaactttgg
     3121 gctttccttc tgtaatcgtt ccagttttat ccaaaacaat gctgtctaag tgagcagctg
     3181 cttctaatgc ttctccgcct ttaattaaaa ttccatttcg tgcaccaaca cccgttccta
     3241 ccataatagc tgttggagtc gctaaaccta atgcacatgg acacgcaatg actaatacag
     3301 agacactatg gatcaatgcg agttgccaat caccagtgat caaacctgta gctatgagcg
     3361 tgataaacgc gatgactaat acgatcggaa caaaaatccc tgagatccga tctgcgattt
     3421 tttggattgg ggctttgctc ccttgagcat cttccaccat ttgaatgatt tgcgctaata
     3481 ctgtctgctt gccgacttgt gtaacttcca tgtgaagtag accattcgta ttgattgtcc
     3541 cgccaaagag cgtgtcatcc ggattctttt ctacaggaag attttcacca gtaagcatac
     3601 tttcatctat cgcactgctt cctgaaataa ttcgaccatc tgctggaatc tgctcaccag
     3661 gacggatgac tagttgatca ccaacgacta cttcttcaat cgctaacgtt tcttctttcc
     3721 cgtttcttat cacttgggcg gtttttgttt gaagagacat caattgtttg attgcattac
     3781 ctgttttcgt ttttgctgta tgttccaaat atttgccgag caaaatcagc gtgatgatca
     3841 tactgctgct ttcaaaataa agatcttggg ggtgtccacg gaaaaatccg ttgtaaatgc
     3901 tcaatgcaaa ggcagccgat gttccaattg ctaccaatac atccatattt ggtgctttcg
     3961 tcttgattgc atggtacgca cctttataaa aacgagcacc gacataaaat tggacaggag
     4021 cagacagcac taactggacg attggaaaat gaaaaaagtg aacaatcgcc gcatggcttc
     4081 ctaacatcat agcaatcatt gacaacatca acggcaaagt caaaaccgta ctcaatataa
     4141 gatcgaatag catttttttc aaatacgctt gcttttcttc tgcaattttt tgtttgtggg
     4201 cttcatcgta caaaattgca ccatagccga tgttttctac gctttggatt aatttttcag
     4261 tggtcgtccc ttcatatttg acacttgctt tttcagtggc caagttgact gtggcattga
     4321 ccacaccagg ttgtccgttc agctcttttt cgatcctagc agaacaattt gcacaagtca
     4381 tacctgtaat gacgaacgta tccattttgg tttctgctgt tgccatcaaa tcacctctgc
     4441 tttataaccc aatccattga ttgcttgaca aatcttttcg gattgaactt ttgtttcatc
     4501 aaacttgacc gtaccgtttg cttttttcaa atttactttc actttttgca cgccgtcaag
     4561 tgcgcttact gtttcttcta ctcttgctgc acaatgattg cagctcatac cttcgattga
     4621 aaattgttgt ttcatttttt cttcctccta ttgatgttgt ttacattcac attgacctgg
     4681 gatacagtta cattcgatcg tatctactgg ttgcttttgt tccagttgtt tcaaaatctc
     4741 attgatatct tcttgagtca aagtggcttc ttctactaga tccgcaatcg tctctccaat
     4801 cctttttgca cagatatggg aaaaaagatt ttccgtcgca ctgcgaactg tttccatctc
     4861 cgagacagct ggataataaa tgaatttttt tccttcttgt tctgtccaga tcacttcttt
     4921 ttttaccaaa cgacccagca aagttttgat cgttgctggt ttccaatcca tcgaatcagc
     4981 taagatctgc gtgatttctt gggctgtcgt ctgtccaagt gtccaaataa cacgcatgat
     5041 ctcccactct gaatcactga tctttactgg cgttttgact ttttccattt atttcacacc
     5101 tttcgtttac aaatgtaatc attatcttat gaatacagat tacacttgta aacaaaaact
     5161 gtcaattatt tttgctctct attttcaatt tagttaaaaa ttcttgtttc tctcgtcttg
     5221 ttttaaggat gatcagttta tttcttgcat tagctacttg gatcagctgc tgtattttcg
     5281 gttcattgtt ttcttcaaaa tgccagataa aagataaaaa ttctaagtat tccctgttta
     5341 gtttctccga aaatgattca ggcatatctg gccgagattt tttgtttatc tttcttttta
     5401 gagaacgcca aactactcgg tagatggcga gataacgcgg cactttaagc caaatgatct
     5461 tatctgcttc tttaatcctt tcctctaatg tagaagtata atttccttca acgatccatg
     5521 acggattaga taccataaac aattgctgtt cttgcaaaaa ccactttttt gcctgaatac
     5581 tgtagtctgt tgtatgccat aaaaggtcta gcggcagtag cggaaagtcg gtgatttctt
     5641 tgatcttcct tgcgagggtc gattttcccg acccactttg tccaatcacg atgatcttca
     5701 ttcttctccc tcacttctct ttggaatttg gttcgatcat accacttata acgccgcaaa
     5761 aaaacaaggg actgtgacaa aagtcgtgtc aaagtccctt gtttcgaa
//
LOCUS       DAZUJR010000121         5784 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.125, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000121 DAZUJR010000000
VERSION     DAZUJR010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5784
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.125"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            290..1282
                     /locus_tag="ACG804_002668"
     CDS             290..1282
                     /locus_tag="ACG804_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4833542.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNLAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            1342..2766
                     /locus_tag="ACG804_002669"
     CDS             1342..2766
                     /locus_tag="ACG804_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HFS4833543.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQE
                     IAAKIDQKGVRSVLQEMKGTMVHA"
     gene            2759..4258
                     /locus_tag="ACG804_002670"
     CDS             2759..4258
                     /locus_tag="ACG804_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HFS4833544.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            4297..5691
                     /gene="uxaC"
                     /locus_tag="ACG804_002671"
     CDS             4297..5691
                     /gene="uxaC"
                     /locus_tag="ACG804_002671"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HFS4833545.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYLTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
BASE COUNT         1901 a         1069 c         1184 g         1630 t
ORIGIN      
        1 tgacgttttg gtcgactaaa ttttaccaaa agtgagtctc tttttgagtt gaaacgaaga
       61 aaaaagtgtt agtagaaaat cgctttcgat tttccaccaa cacaaaatat tatagaaccc
      121 taattaaatg agcattcccc gctttcaaga atagcataat taaaaataaa aatccaagta
      181 atttttaacg tgtgcaatct tttcatatca aagatctatt gacttatcgt agttatcgta
      241 atatgatgaa tgcgttaaca aaaagtgaaa aagtaaggaa aatgatggaa tggtaacgat
      301 caaagatatc gctaaagcag ctggcgtttc tcatacgaca gtttctcgtg ctttgaataa
      361 cagcagttta ataaaaaatg aaacaaaaca aaaaatacga caactagcta aggaaatgaa
      421 ttattcgcca aactatagtg caaaaggttt agtgaatcaa aaaaaatatc taatcggact
      481 atttttctca agtttgcata aaggaacttc atcaaatttc ctagcagatt ccattgcagg
      541 catccattca gtattagaca caaattacag tttatctgtt gaaagtatcg atgttgttga
      601 tttaacagaa atcaacctgc aacgctacga tggactgatc gttatgagtc aaagtgatga
      661 tgatcagcct ttcatcgact atctcaaaga aaaagaattt cctttcgttg ttgtcaatcg
      721 tcacatcaat gatccagcgg ttatcaacgt cactgccgat gatgcggccg gtgttatgca
      781 ggcagtagat tacggtattg gatgcggaca tacgaagatc gcttatattg gcggaaagaa
      841 aaattttcgt tcgacaaaag aacgggaaaa aggggtattg aaaagtctaa aaaaagcgag
      901 catccctgtc aatctagcct attttttaac aggagattac agcttagaaa gcggcctcca
      961 aaacatggaa tacctattat cactttctga cctgcctact ctggtttttt gcggcaacga
     1021 cgacatagcg attggtgcat tgagagctgt acatttagct ggcctccgtg ttccccagaa
     1081 catttctctg atcgggttcg atgattctcc agtcgtctcc tatctcaatc cgccgcttac
     1141 caccgtacgt aagcctttga aagaaatgtg tcaagaagga acaaagcttt tactagattt
     1201 gatcgaaggc aggacgatcg aacaatctaa aattgagctc tccaccttgt tgatccttcg
     1261 tgagtcgatc aattacttgt aaactacaag taattttata taaaaatgtt aacgtgtgca
     1321 taacacagaa aggaagttta tatgaaaaaa ctgacaaaag aattagtgaa aaaaaacgaa
     1381 gcacctgtaa aagttcttca gtttggtgaa ggcaatttta tgcgtggatt tattgattgg
     1441 cagattcagc agctgaataa ccaacaattg tttaaaggta atgttgcaat cattcaacct
     1501 ttagaacaag gtcttggaaa tatgatgaac cagcaagata atttatatac ggtcatttta
     1561 caaggactca gcaatggcga aatcgttgat acttccgaga ttatcaccgt agtagaacaa
     1621 atgatcaatc cttatgatga atgggatgct tatctatctc tagcagaaaa tgacgacttg
     1681 gcctatatcg tctccaatac aacagaggca ggaatccaat tcgtggagac tgataattta
     1741 acagatactc ccccacagag cttcccgggc aaactgacag cctttttata ccgacgtttc
     1801 aaattaaaca aagctggctt taccatcatt ccttgcgaac tgattgacag aaacggcgaa
     1861 cgtctaaaag aaatcatttt acgctacgca gaaaaatggg atttagaacc tgcttttgtt
     1921 gagtggttag aaaaagaaaa tgttttctgt tgtagtttag ttgatcgcat cgtcccaggt
     1981 tatcctcgcg aagatgcagg tgttttcaat caacggcata actatgaaga tcaattgatg
     2041 gtcaaagcag aaccattcat gctttgggtg atcgaagggc ctaaagaatt ggagaatcaa
     2101 ctaccattca aacaggctgg cttgaatgtc atcatcacag atgatatgac tccttatcgt
     2161 gaacgtaagg tgcatttgct taatggaccg catacagcga tggtccctct tgctttgttg
     2221 gcggaattgg aaactgtaga agaagtaatg aaagatcctt tattctccgc atatgttgat
     2281 cagttattca atctagaatt gattcctatg ctttctttac ctaaagatga attagccatt
     2341 tatgctgacc aaatcaaaga acgtttcttg aatccttttg cccatcacaa attagaagcg
     2401 atttcattaa atagtgtttc aaagttcagc acccgtctgc ttccagtgtt caagaagtat
     2461 atcgaagaac aaaatcaggt accaccgtta atcactgttt cactagctgc gctacttctt
     2521 atgtatcgag gcgatcaagt aaagccacat gatgatgaaa agacgataag cgaatttact
     2581 gatgcttggt cgtctgataa tggaacagct attcctcgat tattgcaaaa cgctgcgctt
     2641 tggggagaag atttgtctca aataccgaat gtgacagata cagttcaaga aatagctgca
     2701 aagatcgatc aaaaaggtgt ccggtcagta ttacaagaaa tgaaaggaac gatggtccat
     2761 gcttgaaacc ctgcaaccaa caatgaaatt aaatcgacga gacagtgtgg tcgtcgcatt
     2821 aacccctatt ccaaaacaaa cacaactgac gattgatcag caaacgatca ccactcttga
     2881 agatatcccg caaggtcata agattgcatt gggtgatttg aaagctggag acaacgtgat
     2941 caaatatggc tatccaatcg gtcatgtgac gacagacgta actgccggtc aatggctgca
     3001 cactcataat gtaaaaacca atctttctgg tgaattggat tatcgatatg aaaaagatgt
     3061 ccatccaagt cattaccttt ttgagaaccg aacatttcaa ggttacttgc gaaaaaatgg
     3121 aaaagtaggg attcgtaatg atttgttttt agtacctacc gttgggtgtg tgaatggcat
     3181 tgctgaactg atcgtcaaac agttcaagga aaaacatcca gatctgggac agtttgacca
     3241 tattacgatt ttaaagcatc cttatggctg ttcgcagctt ggaaaagatc atcaaaatac
     3301 tcgagaaatt ttagcggacg cagtaaatca tcccaatgcc ggaggagttt tagtatttgg
     3361 attaggttgt gagaacaata cagttcctga attcaaaaaa attttaggtg aatatgatga
     3421 agaacgagtg aaatttctag tggctcaaga tgtttacgat gagatcgaac aaggtgtggc
     3481 tctattagaa gagcttttaa cagcggcgga aaatgaccag cgcatatcag tcccgctctc
     3541 taagttgaat gtcggtttga aatgcggcgg ttctgatggt ctatcgggaa taactgctaa
     3601 tcctttactt ggtgcatttt ctgactactt gattgctcaa ggaggcagca cgatcttaac
     3661 agaagtgcca gaaatgtttg gcgcagaaca agtattgatg gcacgagcgg aaaatgaaga
     3721 agtttttgac tcaatcgttg acttgatcaa tgacttcaaa cagtatttct tgtcttacgg
     3781 ggaaccagtt tacgaaaacc catctcctgg taataaagca ggtgggatca ctacattaga
     3841 agataagtct ttaggctgca cgcaaaaatc aggaagctct cctgtcgttg atgtgctaca
     3901 atatggcgaa aaaatcagaa aaccagggct tagtttattg caagctcccg ggaatgatct
     3961 tgtagctgcc tctgctcttg cttcatccga ttgccagttg gtcttgttta ccacaggaag
     4021 agggactccg tttggctcat atgtcccaac ggtcaaggta tctacgaata caactctttt
     4081 tgaacgcaaa ggtcattgga tggattttaa tgcaggcgtc ttattagaac aaccaatgga
     4141 agtaatctta gaatcgtttg ttcaaaaaat catcgctgta gctagtggag aagaaacgaa
     4201 aaatgaacaa aatgacgttc gagaaattgc catttttaaa aacggagtaa cactttgatt
     4261 ttcataaaac agtataaaaa gaaagaagga agatttatgt ttttatctga tgatttttta
     4321 ttaaaagacg attgggcgaa aaagctttac cattcctacg caaaaaacat gcccattatt
     4381 gattatcact gtcacttaga tccaaaagaa atttacgaaa acaacaattt cagcaatctg
     4441 acagaagctt ggttaggagg cgatcattac aaatggcgct tgatgcgagc ttgcggcgtg
     4501 cctgaagaaa aaatcacagg aaatgcttct gattttgaaa aatttttagc ttggtgtcaa
     4561 accgtaccaa aaattatcgg aaatccgctt tacagttggt cacatcttga attgaagcgt
     4621 ttcttcggta ttgacttgtt gataaatgaa gaaaatgcag agaaaatttg gacacaagca
     4681 aatgaaattt tggcagctcc tgattttcgc cgtcgggaaa tcgcaaaaaa atcgaatgta
     4741 gaagtgattt gtacaacaga tgatcccgca gacgacttgc actatcatca gttgcttgct
     4801 catgaagaac cagatttgaa ggttctacct tcattccgtc cagataaagc actcaatatt
     4861 gaaaaagaag gatttaatgc atgggtcaca ctactggaag aagcagctga ccaaacgatc
     4921 accacctatc aagaactgat agaagtctta gggcagcgga tagaatactt ccatcaacat
     4981 ggatgtcgtg tttccgacca cgctttagac atcttacgct ataaagaagc ggatgaaaca
     5041 gtattagaag agatttttca aaaagcacga gctaacaaac tattatcttc agatgaaatc
     5101 gatgcttatc ttacagaaac actgatacat ttgacccact tctatcattc tcataattgg
     5161 acgatgcagc tgcacatcca tgcttatcgt aactgtaata cacaaatgtt ggaaaaatta
     5221 gggcccgata ccggctatga tggaatgaat gatctttctt tgactattcc tctgcaaaaa
     5281 ttattgaacc gtgcagaaga aacggatcag ttgccaaaga cgatccttta ttcattgaat
     5341 ccgaatgact atcctgcgat tttagctttg atgggctgtt tccaaaaaga acagaatgga
     5401 aaactgcagt taggttctgg atggtggtac aacgatactc gagctggtat gcgcgatcaa
     5461 ttgacacaat ttgctgatgg tagtgctttg gggaattttg tcggcatgct gacagattca
     5521 agaagtttcc tgtcctacac tagacatgaa tatttccgtc gtgttctttg tgaattttta
     5581 ggcgaaatgg tcatgcgagg agaagcacct gaagatgaac aacttttagg aagtctagtt
     5641 caagcgatta gttatacaaa tgctaaaaat tactttggct tttttgccta attgattaat
     5701 agtaacagta acgaatcaaa aacaggatag tgaaataacg gaatccgttt atccacgttt
     5761 tagagaagaa gacggaccaa attt
//
LOCUS       DAZUJR010000122         5666 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.126, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000122 DAZUJR010000000
VERSION     DAZUJR010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5666
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.126"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..454
                     /locus_tag="ACG804_002672"
     CDS             <1..454
                     /locus_tag="ACG804_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HFS4833546.1"
                     /translation="KELNYELEYEKSICSIPYNNIEEIIEKDAISIYKFFIFIPNRQL
                     KANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESIYNLKKPLRIAIGDSL
                     NDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFERILTI"
     gene            735..1955
                     /locus_tag="ACG804_002673"
     CDS             735..1955
                     /locus_tag="ACG804_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HFS4833547.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            1952..4672
                     /locus_tag="ACG804_002674"
     CDS             1952..4672
                     /locus_tag="ACG804_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFS4833548.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            4656..5600
                     /locus_tag="ACG804_002675"
     CDS             4656..5600
                     /locus_tag="ACG804_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFS4833549.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
BASE COUNT         2107 a          908 c         1113 g         1538 t
ORIGIN      
        1 caaagagcta aactatgagc ttgagtatga aaaatctatt tgttcaatcc cttataataa
       61 tattgaggaa attatagaaa aggatgctat cagcatttac aaatttttta tttttattcc
      121 taatcgtcaa ttgaaagcta atatatttaa ccatttgaaa aagatgctaa atgtgtctgt
      181 tactgaatcg gcacctgtaa atattgaaat cgtacctcaa aatgtatcta aaggtgtggt
      241 gtttgatcgt ttggaatcaa tctacaattt aaagaaacct ttgagaatcg cgatcggaga
      301 tagtttaaat gacttatcta tgtttgaaag tgcagatatt agttttgcaa tgggaaatag
      361 tcatcaagaa atcatgaaaa aagctgatta tgtcactgtt tcaaatgata aagacggagt
      421 atctcaagca tttgaaagaa ttcttaccat ataaactaat taaggtagta tagaacatag
      481 aattctaaat acggaaaaat ggagcataaa ttccagtaca aatagtactt cttcagtgtc
      541 aaacgaagcg aatataacat agatatttag gattgtgaca aaaatcatgt cacaatcttt
      601 ttttcgaata aacttatttt ttgaagtcgg ccatttatcg taatttcttt gcataatacg
      661 aacaaatttt cggttattga tgaaaaaaaa cattgaaaat ggtatgataa aagaaaaaaa
      721 ggaggaaatt tttaatggtg aaatttatcc atgcggcaga tttacatatg gatcggtcat
      781 ttgaaggact gacaactctt gataaaactg tacaggaaaa actattgaag acgaatctga
      841 ccgttttatc aaatatcatt gaacaggcaa taataaataa cgttgatttt gttttacttg
      901 caggagataa ttttcatcaa aatcgtcctt cattaaaaat acagaaacat ttttcagaac
      961 agatgaaacg gttagaaaag aaccatatac ctgtatttat aatattcgga aatcatgatt
     1021 tctatcaaaa agagcggtat tggttctcct ttcctaaaaa tgtccattta tttacatccg
     1081 aaacggtaga gacaaaaaaa ataacgataa aaagtggaga aactgtctct ctcagtggat
     1141 ttagttatcg tcaaccgtgg attcaaaaag acaaagtgat ggaatttcct tctagagaac
     1201 tcacagatta ccatattggg ttgtaccacg gggaacctgg cgtctctcaa aaaggaaact
     1261 atgctccttt ccaaccctca aagatgcaag aaaagggata cgattattgg gctttagggc
     1321 atatccatgt gccaacggtc ttaaatgaaa agcaaacaat tgtttatcca ggtgcgcctc
     1381 aaggtcatac taaaaaggaa caagcttcta catctattct actagttgaa ttaagtaaag
     1441 gaagttgcca aatacatccg attaaagtag cagaggtcta ttggaagaca aaggaaatat
     1501 cattgaggaa agcaagaacg acaaaagagg tcattgttca cattcgtcag cagctttcaa
     1561 aagtagagga tggatttagt ttaattgaga taaaattaaa agattatgac catctcaata
     1621 cagatgtttt ggaacggata caatcaggag agctattaga ctatttgtta gaggaattct
     1681 cagataggat aaatgatttc tttatttggc gtatttctct catagagaat actttttata
     1741 cgaagacccc acttgctgct tctgctaaat tgatggaaca gttatttcaa tactatcaga
     1801 cacctcaaga tttccaacaa attttaaatg aagtatatag tcatcaagaa gcggctagaa
     1861 tattgagcga actgccggaa tatcaagaag aaacacttga aaaagccaag cagctgctta
     1921 atcaagattt tttatttgag gaggatcagg aatgaagatt ttaaggatcg agattgctgc
     1981 ttttggaaaa tggcgtcaaa aaagttttga cttttattca ggcaatcagc tgatctatgg
     2041 gggaaacgaa gcaggaaaat caacgattta tcaatttatt caagcaatat tatttggttt
     2101 cccttcaaaa ggccgtaaaa aaaaggatta tacaccaaaa gacggctcag cctatggcgg
     2161 caaaatatgg cttaaacatc ctgtatatgg tgaatttgct gtcgagcgct acaagcagca
     2221 aaatcgcgga aaatcgaagg tgtggctggg ggatcaagtg ggaagtgatg agttactaga
     2281 aaaactgatc gcacctttga cgaaagagtt attccagcag gtatttactt tccagcaaga
     2341 gcagttgatg gaactagatc atttgagaga aaaagagcta catgatgcgc tgatttcttt
     2401 aggcatcacg ggcagttctc aagtattcca aaagcggcaa gaatattatc agaaagcaca
     2461 acaattattc aagaaaaaag gccaaaaatt actaatcaat caaaaattaa atgaatggaa
     2521 agagctgcaa gaaaaaattc atcaaaaaca agaacaggaa gcttattttg gcaagttgat
     2581 ccaacaagaa caggaatacg agtcgcaaca gcagcagtta ttggcacaat taaaagaggc
     2641 gaacaaacaa ttttcattag ccagacagca agaacttaat ttttctttat atgaagaatg
     2701 gcaatctctc aaaaaaaaca gcactacagg tcttcctgat gagcaacttc ttttagatct
     2761 ggagtctttc tccaaacggt atcagcaaac aaatgagcgt ttggaagaat tagaagcaac
     2821 actggaaaag catagcggga tggatcagca gtcagccaga tattattttt atttagagca
     2881 ggagcaggaa ctaaaagatc tccagcaact tcaatttaca gcggaacaat taaacgaaga
     2941 atggcaaaga ttacaaattg agactagaga aacaaattca gaattgaaga ttttggaaca
     3001 aaggtggcat tggcagaaaa atccgttacc ggaagaattt ttatatgaag aagaatggaa
     3061 gcatcttctg gctgaagaaa gaaggattgc tgatctagaa agccagattt ctgtgcgtct
     3121 ccaaatagct aaagaacagc aagagatgat tgaagcagaa gtgaatgact tggaagagac
     3181 ctatccagca ttattacaaa atcagtcaga gatagcacca gtctcttcat ctaaaccgta
     3241 tatgctgatg gctggcggag caataatcat tgcaggtata tttgtaccaa tgcccttgaa
     3301 agtgatcctt ttactaattg gtgcaggcat gattggctat ttcttctaca aaaggcaacc
     3361 aaaaattaaa actaaaaatg atttctctga gataaaagga atgtggcaag aaaaactagg
     3421 acaacttgat ctagccttag ctcaattagc tgaagcagaa gaaaaacaaa agagaactgg
     3481 agaagaaaaa cagattcttc agcaagaagt atatcgtttt gcggatcatc ggcacttagg
     3541 aaagatggat acgctcaaac tcatgaaaga atatggacag gaagtcatag attatcagaa
     3601 attatatggc gtatttgagc ggaaacataa aagagaacag gaaatacaag aaaaactacg
     3661 acaaatcgac caaaaatttg agtttgttaa agaatggtta ccgatacaag ataagacaat
     3721 ttcagaaaaa atggtattgc tttcccgttt tatacaagag atggaacaga tgaaatttgc
     3781 cagaagctat cagcaaaata ctttattgaa gcaagaaatc aatcaattga aaaagaaaca
     3841 aaaagtatgg atacaagaat acagcgaaca attgactcaa gcaggcttat cttatccttc
     3901 ggaagtacct gtctttttac aaaaagccaa acaagccgaa cagcagatga aaagatacaa
     3961 tgaattatcg gaaatgctta ctccactatt tcctgaagag ctgacaaaag agaaattatc
     4021 tgtaagactg cgccaactga aagaaaagca atcccaactc cagcaagaag aaaaagaagc
     4081 aagtgaaaat cggcaacgac tccaacttca agtagaagag ttgcaaagag acggcacatt
     4141 ggacgaactt tatcaacaag ctagccggca aaaagcaaaa ttacaggaat tactggagga
     4201 atggggagca cttgaaatcg ccgggacatt cttaggtgat ctttcaacag agatgagtga
     4261 aagacaatta ccccagttgt taagagcagc aggtgattat ttaggtattt taacaaaagg
     4321 aaattatcag aagatattac tgaaaaatga tacactgact ttaacagacg gatatacaga
     4381 atttcccatc tatgagttat ctacaggtac gaaagatcag ctgattatgg cgatgagatt
     4441 tgcttacctc tcattagaag ctaaccgttc gatatgcccg atcatcattg atgatggctg
     4501 gcttcattat gatcatcagc gaaagtatca attagctgaa cttttagcta aatttggaga
     4561 aaagtatcaa ataatttgtt tttcttctga taaagaaatg gtaagctatt accatgagat
     4621 gaaccaaatc gtaaaacaat tagaaggagc aaataatgaa aaaaattcgt gatttagtaa
     4681 tcgatgagca gtttgaacaa tttgtcctga tcaaaagtgc agatgtaaga atcgctaaaa
     4741 acggaaaaaa atttattgct tttactttcc aagatacttc aggtactatc gatggtaaat
     4801 actgggatgc ttcggaggag gaaatcaata aatttacagc cggcacagtc gtttttctaa
     4861 acggtaaaag agaggtttat caaggaaacc ctcaagtaaa gattcttcat atgcgcttaa
     4921 caagggtaga tgagccagga gagcctagtt tatacatgga aagagcccct ttgaagaaag
     4981 aagaaatgga agaagaaatc aatcaattgt tgtttgagat caccaatgcg cattggaatc
     5041 gtattgttcg ctatctactt aataaatatc aaaaacaatt ttttgagttt ccggcagcaa
     5101 aaagaaacca tcatgcattt gccagtggat tagcttatca tactttgaca atgcttcact
     5161 tagggaaatc aatcgccgat gaatatcctg agctgaatcg agcattgttg tatgctggta
     5221 tcattttgca tgatttagga aaggtgattg aactttccgg tcctatgtcg acagaatata
     5281 cgcttgcagg aaatttgatc ggtcatctgg tattgattga cgaagaaata actaaagcct
     5341 gtcttgcgtt gaaaatcagc gaagctgacg aagatgttct cgtattacgt catatggttt
     5401 tagcacacca tggcttatta gaatatggct cacctgtacg tccaagaata atggaagcag
     5461 aaatattaca tcaaatcgac aatatcgatg cttcgatgca gatgatgttg acttcgattc
     5521 gtcaaacaga accaggaaaa tacaccgatc ggattttcgg tatggacaac cgaagtttct
     5581 atgtaccaaa agatttatag caaaaattta tttttttcat tcaaaacaaa aaaagcgaga
     5641 cataagtctt cgcttttttt gttttc
//
LOCUS       DAZUJR010000123         5617 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.127, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000123 DAZUJR010000000
VERSION     DAZUJR010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5617
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.127"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(158..616)
                     /locus_tag="ACG804_002676"
     CDS             complement(158..616)
                     /locus_tag="ACG804_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFS4833550.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(629..1960)
                     /locus_tag="ACG804_002677"
     CDS             complement(629..1960)
                     /locus_tag="ACG804_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HFS4833551.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(1971..3413)
                     /locus_tag="ACG804_002678"
     CDS             complement(1971..3413)
                     /locus_tag="ACG804_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFS4833552.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(3400..4164)
                     /locus_tag="ACG804_002679"
     CDS             complement(3400..4164)
                     /locus_tag="ACG804_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HFS4833553.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(4268..5143)
                     /locus_tag="ACG804_002680"
     CDS             complement(4268..5143)
                     /locus_tag="ACG804_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFS4833554.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(5398..5482)
                     /locus_tag="ACG804_002681"
     tRNA            complement(5398..5482)
                     /locus_tag="ACG804_002681"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5446..5448),aa:Leu,seq:caa)
     gene            complement(5500..5571)
                     /locus_tag="ACG804_002682"
     tRNA            complement(5500..5571)
                     /locus_tag="ACG804_002682"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5537..5539),aa:Gln,seq:ttg)
BASE COUNT         1727 a         1183 c          839 g         1868 t
ORIGIN      
        1 cctgaaaata agttttctaa atcataggag caacaaaaaa attcgataat taacaaaaat
       61 caaaatgatt aaatctagtg attgaaacat atcatttcaa aaaaattttg taaattcacc
      121 cataaatatc accctattta acttttttca tcgtacacta aaattcaaaa caactatctt
      181 taatctttac ttcttggttt tgttttaata aatttccttc aaaaatgcct ggagaaacta
      241 caatgatcac cgtatctttt tgtgcttgct ccaacttctt caaatctata atagctaaca
      301 gtgtcccttc ttttacctcc tggttacttt caacccgtat ctgaaacgga cttccttcga
      361 gttcaactgt atctaaaccc atatggatca gtatttttct gccagattca ctttcgatcg
      421 ttatggcatg tcgggtagga aatatattat cgattattcc tttaactggc gcatggatat
      481 atccatcatg attcgttata gcgtatccaa ctcctatcat ttttgaagaa aagacctcgt
      541 cttttactgc tgttaatgga ataatttgac cactagctac agcttttaga atgtttcttg
      601 ttttaaagaa atgcactttt tatcacctct actttaatgc tggccaatat tttttgttta
      661 ctttgatcat ttcatctagt attttttttg cgactctggc atttggtacg gtttgattca
      721 atgtaaatgc ttgtaaagct ttttgataag aaccttcaaa gtaagcatct actagtaact
      781 tctctactgc aacttgtgcc tccatcaatc ctttatgaaa atcactgatt ggttttctta
      841 gtgtaattgg ctccacacca gttgcaccaa catatgccgg tatttcaaca actgcatctg
      901 accgtagatt cggaatcgcc ccttgattag gaacgattag cataaagcga cgacgatcat
      961 cattcaacaa ggaaatagct atatcgacga tatattgtcc atgctcccca aaattaaagt
     1021 tcaatacttc ttccacaata ccgcggcgta ttttatcagc catttctttg gtatttttct
     1081 ctcgtccatc catgaccata ttagcacgtg tatactcttt gtcagtatgc tcaacgacca
     1141 tatcaggata taagtaatac tctaagtaat tattcgggat attacttgga aaatttttcg
     1201 tgatgactga catcatttga aaggtttttt gccaagtttt atctcctata ttaaaatcgg
     1261 cgacttgcat ttcttttgtt attagttttt caataatctc tggcataatt tctcgttgca
     1321 attctttatc ataaatcgat gtataccagc caaagtggtt taaaccataa tacgtaacga
     1381 tccaattctt acgatcataa ccgtaattca ctgcaatcgt ttcttcaatt gaaatagtca
     1441 tatcacaggc attaatcatt tttacattcg gatatttacg acgaacagct tcagaaacga
     1501 tcgactctgg atttgtataa ttcaaaatcc atgctttggg ggcatagtct tgtatatgat
     1561 cgacaatttc caataaacct ttgattgagc gcatcccata agcaaatcct ccgagtccac
     1621 acgtttcttg tcctactaat ccatgtttaa gtggaatctt ttcgtccttt tctcgcatct
     1681 ccaatcctcc aacacgaatt tgtgagaaaa caaaatcgca tcctgtaaaa gcaagctttg
     1741 gatcatccgt tgcacgaatg cgaatatttg aaaaaccttt tcttttcagc ataaatttaa
     1801 caatcaagta catatccata tttctttctt catcaatatc atataaacgt atttcagata
     1861 atggcaaccg tttttcattg ttcaaaatgg cttgaacgat tcctggtgta tacgtactcc
     1921 cgcctccagc tatagtgata atctgttttt tcatcatcat cttttccttt ctattcttct
     1981 aataatttat tgaattctgc cataacataa gtcacttcta agccgatgat aatttgataa
     2041 tttttttcag ttggtttaat gatcccgctt atccctaatt gcttgattcg ctgttcctcg
     2101 accatggtgg gatccactac ctctacccgt aggcgtgtat tacaactata gacatccagg
     2161 atattggctt ttcctccaaa cgcttgtagc atttttgttg ccatatattc ataattttta
     2221 cttgctaacc ctaactctgt ttcttctaag gttacttcat tgccaaactc tgccttagct
     2281 tcacgtccta atgtctgaat gtttctctta ttgatcaaat aataaaaagt aacgtaatac
     2341 aaggcaaaaa agaaaattcc gattggaaga atcaaaatag cattggtagc gattcgaaaa
     2401 ttgatgagat aatcaacaat acatgctccg aatgtaaaac caattcgtat attgaataag
     2461 taacagacaa tccctgctaa accggcaaaa agtgcatgga tcacgtacaa cataggagaa
     2521 agaaacatga aactaaattc aacaggctca gtgatatttg caataaatga agttcctgca
     2581 ccgcttccca tgattccttt gaccatctct ttattttctt tataagctgc tttatagata
     2641 gctagacata tagctggtat accaaacatc attactacaa aaaaaactga taaaaacagt
     2701 ccagcctgag gatctccgtt gataaagcgt gtcatctctc ctctgaaaac ttccttgcta
     2761 ggagatgtat agcttcctaa atcgtaataa atatacgtat tcaacacatg gtgcagtcca
     2821 aaggggatca gcaaacgatt caaaaacata aatatcccca cacctaatgc tcccatatca
     2881 acgagcagtt ttgcaaaatt atcaatccca atttggatga gcggccagat aaagcccaaa
     2941 aaaacagctg cgattgtttg tagaatcatc accatagtca atgggaattt ttcgcccgca
     3001 aaataagaaa aaactactgg taatttttgt tctttaaagc gattatacgt ccatgccgct
     3061 actaaaccgg aaataattcc accaaaaatc cccatattca cttctgggtc cataatttct
     3121 aagccttttt tcaaggtagc aatcgctaaa aaaccagtaa gtgcaggtat tcctttgtcc
     3181 ttatttttga caaaaccgat tgcaactcct atagcaaata agatatccaa gtttccaaaa
     3241 acggcatttc cagctgcacc aattactggg atgttcagca tatcgtcagc tgataaacgc
     3301 atgatcaatc ccgctaatgg catcgctgca actggaagta gcatcgctct tccaagcttc
     3361 tgcacatttg atttaacatt catttttatt cctcctctat taaatatcct catatgttac
     3421 taactcaatc aaaggatcat ttttcacttt ttgagcaaat gctgaatgaa ttaaaaattc
     3481 gacttggtgg gtacgaggat acacaaaact tgaaccattt aacaattcct gatccaaata
     3541 cgctgcgtga cacatgactt cgatcgtttt atcttctctc aatatcatga gtaaacttgc
     3601 caaatattct tccacactcg tattgatttg tcgttttttt tcatcagttt ctcctacgac
     3661 atcgaaacaa ggctcaaaat aatcgacatg acgaacttca tcttttcgtt caaagttgct
     3721 ccgaaccggc aaatcatatt tttttgctaa tgtaacaact acctcctgat tttcatccaa
     3781 agtatgagta tgatgatgac tgtctaaatg agttggtatg atccccgcat gataaatttt
     3841 ttgaatctga gcattccatt cctgatacag ttgatctttg tcaatgttaa atggatgctg
     3901 ataataagat aaggatctga actctccgct ttcgataaga gtatcgacag ttttgaggag
     3961 tggtttgcca cacgtcaatg ttaaatggac tcctacacct agcctaggca tttcctttct
     4021 tagtttcaca gcatgctcga aacccggcat atttgccatc aatgtagttg atgtcaaaat
     4081 tcctcgctga taagcatcca taatcccata attcacacca tggctatagc caaaatcatc
     4141 cgaattaaaa atcacttttc ccatttcatt ctccttcttt tttctactaa aataggcgca
     4201 accaaataat catagtccat ttactatgtg tcatttggtt gcgcctatag atagttacgc
     4261 ccttatttta atagattctt gctagatgaa ttgccaaata gatgatttca ttttcttgaa
     4321 tggcaagttg aaattgctgt tcgatgatat ctttaatctt tagtgctgta caatacgctt
     4381 tgctatgttt aaatgtttca gtaaaaaaac caatattttc tactggcgtt tcttcctgat
     4441 aaatcaagcg tttaaccagg aatttgatat gaaccattaa gcgatgataa gtcagtgatt
     4501 ctttatcata aacgtttgaa taggattttt ctagatggga caaaatcgtg gtcgtcattt
     4561 ctactatttt taagctcttt aaactattag gctctcctag ctcagcatta atgatatgca
     4621 tagtgatgaa tcctacttca tttgacccta actcggtttg atatcgatga ttgattcgct
     4681 cgaccacttc tactgctata tcatattcat ttggataaag gaatctcatt tctggcaaca
     4741 taattgctgt gacatctcta tcttctcttt ttcgttgaat agcaaaataa atatgatctg
     4801 tcaatgtaat atagatattt gaatctaatg gagaggagat cctagctgtt atcagttcaa
     4861 tcacttcttc cgcaaaatcc ataaattcga ttggaatctg cgagactatc tcactgaatc
     4921 gtttgatctt ttctttagaa tctaatacaa ataatttgtc agcatcctca acatcaaatg
     4981 gcttactcac tttagcagaa aagccaatcc ctttccccat cgcaattttt tctattccat
     5041 cgtcatcgat caatacagca ttatgattca gctttttcat cacatacacc gttaattcac
     5101 ctcctctata tgataaaaca aaacaacttg cagactcctt catacatatt tttgtctcca
     5161 aacaattttt aaagacaaaa aacgacctaa gaaagaaccc tttcttaggt cgtgcctaat
     5221 tgaatagtag caccctacat aatttacaaa aatagtttaa cacataataa aagcgttatc
     5281 aatatctttt ttactcgttt tatgataata cttgtatcga attgatttgg aggtaattac
     5341 ataaaaacaa aaaaaatata gcaactctct ataagaaagt tgctatattg ataattatac
     5401 cggcggccgg ggtcgaaccg gcacgtcctc aacggacact ggattttgag tccagcgcgt
     5461 ctgccaattc cgccacgccg gcaaatttaa aaataataac tggggtagct ggattcgaac
     5521 caacgcatga gggagtcaaa gtcccttgcc ttaccgcttg gctatacccc aagaataaag
     5581 ggcgaatgat gggaatcgaa cccacgaatg ccggagc
//
LOCUS       DAZUJR010000124         5476 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.128, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000124 DAZUJR010000000
VERSION     DAZUJR010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5476
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.128"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..682)
                     /locus_tag="ACG804_002683"
     CDS             complement(<1..682)
                     /locus_tag="ACG804_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element ISEfa7 family transposase"
                     /protein_id="HFS4833555.1"
                     /translation="MQGVIAMMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFE
                     FIYPIVEATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDTNVAYRWFLGYS
                     FEEKIPHFSTFGKNYVRRFRETTVFEDIFAYILEQAVKAGFVTEDNLYLDSTHIKANA
                     NKHKFTKEMTHDEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKLKERKISKADPE
                     SGYYVKGER"
     gene            complement(654..1853)
                     /locus_tag="ACG804_002684"
     CDS             complement(654..1853)
                     /locus_tag="ACG804_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HFS4833556.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDIEGKVLSMYARGMSQCDIAATVEDIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKVRGVEDVFFISMDGVSGLKEGAKAIFPSVIVQRCIVHLVRNALRYLPSK
                     DYKEVCRDMKKFYSASSLNAAHAAFDSFQNRWSHYSGAVDVCKRNFSHVEQLFDYGSA
                     IRKIMYTTNAVESIHSSFRKVTKKGVFSNENAQTVDKVHFMDDVYSLFFYNRFMKTNA
                     RSDSYDV"
     gene            complement(1983..3359)
                     /locus_tag="ACG804_002685"
     CDS             complement(1983..3359)
                     /locus_tag="ACG804_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4833557.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGVVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            complement(3359..4015)
                     /locus_tag="ACG804_002686"
     CDS             complement(3359..4015)
                     /locus_tag="ACG804_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4833558.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            complement(4025..5302)
                     /locus_tag="ACG804_002687"
     CDS             complement(4025..5302)
                     /locus_tag="ACG804_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4833559.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            complement(5321..>5476)
                     /locus_tag="ACG804_002688"
     CDS             complement(5321..>5476)
                     /locus_tag="ACG804_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HFS4833560.1"
                     /translation="DKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPVDA
                     ISYGVRK"
BASE COUNT         1695 a         1014 c          701 g         2066 t
ORIGIN      
        1 ctcgttcgcc tttgacgtag tagccgcttt ccggatcagc tttacttatt tttctttctt
       61 tcagcttcac ttccttttct aagtccaaag taaaagggcg ttttccagcc tctattcgtt
      121 gacgattgat ctcatcttct aattcatcct gataggcttt cgcttcatca tgggtcattt
      181 ctttcgtaaa cttatgttta ttggcgttag ctttgatgtg ggtagaatcc agatacaaat
      241 tatcctctgt tacaaaacct gctttaactg cttgttctaa aatataggca aaaatatcct
      301 caaacaccgt cgtttctcta aatcggcgaa cataattctt tccaaaagtt gagaaatggg
      361 ggattttctc ctcgaaggag tagcctaaaa accagcggta agcgacattg gtatcgactt
      421 ccttaatggt ttgtcgcatg gaacggatac cgaataaata ctgaataaac accaatttga
      481 tcagaatcac tggatcgata cttgggcgac ctaaatcgga gtaagtggct tcgacgattg
      541 gataaataaa ttcaaaatca agcgcggcat caatctttcg aacgagatga tcttgaggaa
      601 ctagatcatc aatcgtaagc atcgcaaatt gatttctacc attcgtattg tttttagaca
      661 tcatagctat cactccttgc attcgttttc ataaatctat tataaaagaa aagactgtag
      721 acatcatcca taaaatggac tttgtctaca gtctgcgcat tctcattaga gaacactccc
      781 ttttttgtga cttttctgaa gctagagtga atactttcaa ctgcattagt agtgtacatg
      841 atttttctaa tggcgctgcc ataatcaaag agttgttcaa catgagaaaa gtttcgtttg
      901 catacatcta ctgcaccaga ataatgagac caccgatttt gaaaactgtc gaaggcagcg
      961 tgtgcagcgt ttaaagaaga agcactgtag aattttttca tgtctcgaca gacttcctta
     1021 taatccttac ttgggaggta tcgtaacgca tttcgaacaa gatgaacaat acagcgctgc
     1081 acaatgacag aaggaaaaat tgcttttgcg ccttctttga gaccggaaac accgtccatc
     1141 gaaatgaaaa aaacatcttc tacaccacgt actttcagtt catcaaatac ttgcatccag
     1201 cgatttttag attctgtttg attgagccat aggcctaaaa tctccttgtt tcctttaaga
     1261 tcatagccaa gaatggtgta cacagcatat tctttagctt catagttttc gcgtaaagtg
     1321 acgtacatac aatcaacgaa tagaaatgca taacacttgg ctaatggccg agcttgccat
     1381 tcttccaatt caggaaggac ggcatccgtg atatcagaaa tcatttcgtg ggaaatatca
     1441 aagccgtaaa tatcttcaac ggttgcggcg atatcgcatt gactcattcc tcgtgcatac
     1501 atggaaagaa ccttaccttc gatgtcggag acatctcgtt ttctattagg aatcaactca
     1561 ggttcaaaag aagcctcccg gtctctggga acatcaatgt ttactttacc aaagctcgtt
     1621 ttaagcgtct tattgccata accgtttcgt cgattgtcat gtttctttgg ctctttagaa
     1681 tgggcgtcat accctaaatg gttattcaat tctccttgaa gcattttttc aaataaggga
     1741 ccaaacacat cttttaaaac atcttgcata tcctctacag attcgggttg ataagtattc
     1801 aaaatggatt cagctaactt ctcagcatca ggatttcttt tctttctagc catcgtgtaa
     1861 tcacctcttg atcttatttt agaaaaataa aaaccgtgaa gcaaccaccc gcctaggatt
     1921 gatggttact tacacggttt atattacact ctcatttttg gtgctaaaaa gcaccgaaaa
     1981 ttttaattat tgtcaattaa taattctttt ggattccttc ttaatatatt gaatgaagaa
     2041 ataatcaatg atacaagaag tactaaactc ataaatataa ctacataaat catgaattta
     2101 ggtaatacat tgatatctaa acttgataat gtcttgttaa atccttcagc ttctgcccca
     2161 ccacctaatt ggctagatgc agattgttta gctatttgtt tagctatatc accagtaacc
     2221 ttattcaata tattattccc aagcttgtca gctgtatatt gagctaagaa ataggaacca
     2281 acgaatgcgg ggattgatat aaataccatc tcaattagga attgaccaaa aatttctaat
     2341 tttgatatac ctaatgatag taatactgct atttctttct ttctagcatt catccataag
     2401 aataataata atgaaactac aactcctgca aatattaatg agccaaaaaa taatttattt
     2461 gaaattgagt aaatacctga tatagattgt tgtaatgcag ggtaatttga tgaactttta
     2521 atcaaattat attctctcca atttatatct aatttcccaa gatcttttat tacactatca
     2581 agattcttat caccttttac aaagaatgtt gcatcttggt atacagctgt atcttcggta
     2641 ttaccataaa ctttagcagc tgtatgaata tcagtgatta atgtattttc gtatagttct
     2701 tgtgctgcac ttactacacc gctattatgc ccatcgaata gacctttaat ttctacttct
     2761 actgtttcat ctgcaccttt ctcattatca gcatcaaata aattagattt tatttttatc
     2821 ttatctccaa ctttaaggtt atttttttca gctaaatctt tatgcattaa gattttattt
     2881 ttatcttcat tttctaaatg ctttccttct actaatttat atgcttctga tacaaatttt
     2941 gtttcttttg ttgagtcgtt aaccccagtt aacataactg ttcttttaaa attctttgct
     3001 ctttcaggtg attgattcgc aagagtctct tgagtttcaa taatatcata atcaactaaa
     3061 tctgcaacac tgtttattct ttttacatag gagtctatac tatctgtttg agatatcttt
     3121 ttaatatctt caccttttac atttccccca cctctaggtg ttcctggatt tacttgtcta
     3181 tttatctcca tagaaaaact atttgttata ttagcaaatg tttcttttga agctctgtcc
     3241 gtagcatctt taatagataa actaatgaga cttaaagttg acatagataa aataactaat
     3301 atgataatta atgattttaa actttttcta gttacataag caaatgcatt ttttatcatt
     3361 attcaacctc caaattcatt ttatttactt ttttcaactt tttaccactt agttctaaaa
     3421 tgatatccgc agaatctgct acttccttac tatgtgttac aactattaca catttatttc
     3481 tatctttagc taatgtcttt aatatattaa ttatttctcc agcagtaaca ctgtctagat
     3541 taccagtagg ctcatcagct agtattattg gagcatctga taccaatgct ctagcaatag
     3601 ctactctttg ttgctgtcca ccagataatt tcataacatt tctttttatt tgttttttat
     3661 ctaaacctag ttcaaacaag atactttcat ctgctgattt atttactaat ctaatatttt
     3721 caattggtga taaataatct attaaattat agttttgaaa tactaaagat atattatttt
     3781 ttctatgatt actatatcct ttattttgta tatcttcatt cttaaacaat atttttcctg
     3841 tttgaggttt atcaagtcca gcaagtaagg aaagaagtgt agattttcct gttcctgact
     3901 ttcctactat cgcataaaac ttcccaagtt caaatttttg atttactcct gacaaaactt
     3961 tttctttaga atttgcataa ctatatgcta cattctttat ttctaatata tccattattt
     4021 tctcctaact tatttttgat aagatttctt taggcttctt gattaacatt aatgaagaag
     4081 caaatacaac tgataaaaca ataatactta ttaatattaa ataactttgt ccaagtgttg
     4141 ttatatttga cataaaacta ctattattta ttaaacttcc accggaaatc attgaatcct
     4201 ctgagttaat gaatccatct acaattactt ttagtaatac atttcctaaa aataaggaag
     4261 atattatact tggtatcgat atgaatatta actcgaatat aaattgcatt ataatttgta
     4321 tcttagatgt tccaatagat aagaatatac ctatttcata aattctttcc cttaaccata
     4381 gaatcaagat taatgaaaga acaaccatcc cacctaacat aatagaataa gtcattactt
     4441 ttattatata ttttattcca ctcactgact ctaaagactc ttcaaacgca ttagaatctt
     4501 tttcaacaaa atactttgac tcatcaattt taagctcttt caatttgttt aaggctaagt
     4561 ctgtagattc tgcactacca gaatacatta aaattttatt tgcaatttca ttattttctg
     4621 aattatttaa tatctcttgg cttgttgaat aatctacaaa caccatattt tcactaaaat
     4681 cagaagataa tcctgtatat gtttcctgtt ttttaccaga aaagatccct ataattttaa
     4741 atttatgact ttttattttt ccactttttt caatatctag taattcaaga tcaacttcat
     4801 cacctaattt tagattgttt tgtttagcaa attcttcatg aacaataatt gaattcttat
     4861 cattttcttc tatattttta ccttctttaa ttgtaaatac tccactacta aataaaatat
     4921 ttcttttagt attatttgta gcttcgagtg aaacaacatt cttaaattcg tcagataaat
     4981 cttctctatt tattctttgt tctccgctaa ctactttagc atcttttagt tttgctaatc
     5041 catcatattg aattattttt tcttcaattt cttttaattt ttcaatatct ttaaattgat
     5101 taacattaaa atatttacca tctttttttg ttattgatat tgaagaatta gaactttcat
     5161 ataaagcctt ttctatttca ttgcttgatt tcattattgt taaacaagaa tacaagcaag
     5221 aaagaactat agttaatatg ataaaaatta ttaaagttct atttttcttt cttgtaatat
     5281 atgctatagc attttttatc actttcctaa ctactcctct ctattttctt actccataac
     5341 taattgcatc cactggacaa gcatttttac atcgtccaca tctgatacac tccagatgat
     5401 tgcaattctc aactgaatct ttattcattt ggcaaacttt tttacatttt ccacaattaa
     5461 tacacttatc cttatc
//
LOCUS       DAZUJR010000125         5444 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.129, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000125 DAZUJR010000000
VERSION     DAZUJR010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5444
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.129"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..571)
                     /locus_tag="ACG804_002689"
     CDS             complement(<1..571)
                     /locus_tag="ACG804_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HFS4833561.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNG"
     gene            complement(905..992)
                     /locus_tag="ACG804_002690"
     tRNA            complement(905..992)
                     /locus_tag="ACG804_002690"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(958..960),aa:Ser,seq:cga)
     gene            complement(1137..1703)
                     /locus_tag="ACG804_002691"
     CDS             complement(1137..1703)
                     /locus_tag="ACG804_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFS4833562.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            1958..3289
                     /locus_tag="ACG804_002692"
     CDS             1958..3289
                     /locus_tag="ACG804_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HFS4833563.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGVFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSVLSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGILLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLSGIREIFDSSGKLTT
                     DFIANSGIGATLINMGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            3255..3605
                     /locus_tag="ACG804_002693"
     CDS             3255..3605
                     /locus_tag="ACG804_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833564.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(3697..4116)
                     /locus_tag="ACG804_002694"
     CDS             complement(3697..4116)
                     /locus_tag="ACG804_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HFS4833565.1"
                     /translation="MMTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVTFEPGCRNHWHVHTDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(4117..4461)
                     /locus_tag="ACG804_002695"
     CDS             complement(4117..4461)
                     /locus_tag="ACG804_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HFS4833566.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVEWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            4811..5407
                     /locus_tag="ACG804_002696"
     CDS             4811..5407
                     /locus_tag="ACG804_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFS4833567.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT         1513 a         1008 c          930 g         1993 t
ORIGIN      
        1 ttccatttga tagcgagcga taattgttca gattaaataa ttgataatca aatggcggat
       61 tatttgtcaa cacaccgaca ggattatcat ataaatgaag tccatctttc atactttcaa
      121 ttactatcga tttttcttta tcagctaata accagtgtaa aggtgacaag ggtagttttt
      181 cactaaaatc gatattgact agattgatag tagccaataa ttctttagct tcgtctatgg
      241 ttgagcattg ccctagtatc catggaataa actcaaatgg tgcaacgtta tcttttcctt
      301 cttgtaattc tttataatca gcattgccag gaaaattcag tcctgccata ctcaaccctt
      361 tttcatttgt agcctcataa tagagtggat agttggatac cccagctgct attcctatca
      421 ttgcataatg tttatctaaa ttttttacct ttctaaaatc gaaacgataa tttcttggag
      481 taatagtgac cacttcatta taagacatct cataatcaaa attccttcca aaataatggt
      541 ctttcgttgc ataagtgatt gcggtacaca tcgtttcccc tcctaaaaca aatcgttttt
      601 acacttttat cttacatcta gtattttttt tatcaaaaaa aggccaaaga agattgattt
      661 actagcattt ataaaaaata gtactcaggg ggaatcaaaa aatattgtag gttaaaagta
      721 caacaataag gggctgtgac aaaagtcttg tcacagcccc ttattccgaa caaacggtgt
      781 tcaaaagctt gcatctgcgg taataagccc aatcaaacga aaaaatagga aaagctattt
      841 ttgtttggcc gttcttatta cttgatgcag gacagcttct tcacaacctc taatcgttga
      901 tataaggaag gtacaggatt tgaacctgcg cgccggtatt agccggttcg ccggatttcg
      961 agtccggtgc attaccactc tgccaacctt ccgtaagtac tatttttaaa cttttttcac
     1021 gaaatgtcaa gcctatttct aatagataaa taacagaaat cgcttttttt agcaaaaaag
     1081 tccattgaca gtttgcagcc aacggactta ccgatcaaat tcatactgat agaacactat
     1141 ctgattattt caggattatc taatgctaaa atcgagtcaa ttgtccgttt gatcagtgca
     1201 atgatttgtt cttctgttgg atgcatgatg tttgatgaca tcaatgacgc taagccagtc
     1261 actgctaccc atgtaccagt atgcagagca tcgacatatt catccgataa ttgattgtat
     1321 ctttcatctt ctttaactat ttcacggaaa taattgtatg aaaaatcatg cattttcttt
     1381 ccgtccccat gttcatcaat gtacaatgcc atgtaaagac tatgatgctt ttttgcaaag
     1441 tagatatagt tcaaaccgag atcaatgatt ttatcaccag tacgttcaat agggaaaaca
     1501 tcttctttta gttgttcaaa gatagaatcc agcaacgtat tttttaaatc ttccatgttt
     1561 ttgaattcca gataaatcgg ctgtgtcgaa atccccatct ttttagcaat atttctcgca
     1621 gtaaatcctt taaacccttc ctttgcaaca acatcataag cagcttttag aatttgatcc
     1681 ttggtataga cttttcttct cattaaaact cccccacttc tttactgcag tatatgttgt
     1741 tttattgtac cctattttta gcattttttg caaacatttt actcaaaacg ttatatttta
     1801 aatttttttc agtcttcttt aacttttttt tgcaaaatta aaaaaatttg gttaaattca
     1861 atgggttccc ttacattttt agttttgacc taaatgatag ttgtccaaat ctttcatttc
     1921 aagttatagt taaagaaaat gaaaaagaag gtgtgtaatg gaaaacgaaa ctgacgttat
     1981 ttatattcat cctcaaaaac gaatcgtttc acagaaaaga aagtattttt atcttggttt
     2041 tacaggtgtt ttttttcttt ttattggctt gctttctaat actcctactg ataattggag
     2101 tggattgcta actattctta cctcgccaag caatcttttg acagattatt ttgctttagg
     2161 tgttttcgga agcgcattca taaatgtagg gattttgacc ttactttctg tgcttttagc
     2221 ttatcggcac aaggtgattt taaacggtcc cttatttgct tcgattctaa cagttaccgg
     2281 tttctctttt tttggcaaaa acctttataa ttctatctca atcattttag gtgtgtatct
     2341 atacgctgta tttgtcaata aacctttttc tcagtacatc atgatcggac tgtttggtag
     2401 cgtattatca ccggtcgtta gttatatcac ttttggtatg cgttttcctt tactgatagg
     2461 tattttattg gggaatttag ctggcatagc aattggtata cttcttccgc ccttagctgc
     2521 tcaaacttta gttttccatc gtggattcac actttataat attggattca cctctgggtt
     2581 gattgcgatg acttttactg ctgttttgag gttattcagc tattcaatcg tcgaaaatac
     2641 attggttttc aatgaatatc actttcctct catttggatt atttttggct ttttttcgct
     2701 gacagtcgga attggtttct attataattc ctttcggctt tcggggattc gagaaatttt
     2761 cgattcatct ggaaaattga caactgattt cattgctaat tctggtattg gtgctacttt
     2821 gatcaacatg ggcttagttg gtctgatgct gtcttcttat gttttgctgg ttggcggtca
     2881 gttaaatgga cctgtcatcg gtgctatttt atctgcggtg ggtttcagtg cttttggttg
     2941 tcatttaaaa aacagttttc cgatactagt cggaatattt attgcttctt tgtttggaac
     3001 ttttcatgag atcaccagta ctggcatgct tgttgcagct gtgtttggga caggtcttgc
     3061 gcccataagc ggtttttacg gcagttttta cggtgtaata gctggtgtgc tacatattgc
     3121 tcttgtccat aacgtcagca ctttgcacgg aggactaaat ctatataaca gtggtttttc
     3181 aactggtttc gttgcaggta tccttgtacc gatactagat aactttaccg ctgtcagaaa
     3241 ggaaaaaaag acacttggaa aaagaattat caaaaagaat catcgatgag cttcttactt
     3301 atttatattc ccatgaaata actgaaatac gtattggagt agaatttgct gaggaagggc
     3361 ttttcataga gatacagggt acggcagaaa ctcagccaga agatttagat gtacttgctg
     3421 atttgctgaa caatcctcgg gaccctagta tggaaatcta ctatcaagaa ctattaggta
     3481 atccccgaca tgatcgggaa gattatcatc tgttaggtag tttgattgat gacgtggaaa
     3541 tcatgtatgc ccagccgatt atcaatatta agatctttcg acgtgcttct cattcctatt
     3601 attaacccta ttttctattt ataaaagact gaatcaaaaa agcagctcct gaaagttcga
     3661 ttaaaatcta ctttcaggag ctgttcaagc ttgacattat tgattttcca atccttcata
     3721 cacttcatct gttacaggtt ctaaaaactc tgaattacca gcagtgatcg ccaaatgttc
     3781 aaaccaactg tcttttgtcg caccatgcca atgtttaatc cctttgtgcg ttacgacgac
     3841 atctccagcc attaatcgtc ttgctggctt tccttcttcc tgataccagc cttctcctcc
     3901 ggtcacaagt aagatttgat agccgtctgt atggacatgc cagtgattgc gacaacctgg
     3961 ttcaaaagtt acattaccta caccaacaga aacttcggga tcattcacta acatattcag
     4021 atagctttgc ccggtaaata cttgagcgta agcttcgttt ttttcacctg ctggaaaaat
     4081 cacgccattg tgtatttctt cgtgttttgt catcatttac gcctctttct tatcttcgct
     4141 attttcttct aaatagattt cttttgctaa actaaaagct gaccaagctt ttggccattc
     4201 tacataaaaa gctaaatggg taatgatttc tgctatttct tcactagtaa tgccattttg
     4261 cttgccaatc ttcagatgag ctggcaattg ttcaaaattt cctcctgaaa ttaatgcaga
     4321 tatggtgatg atactacgct gatgagcaga taattcttct ctggaccata cttgtccaaa
     4381 taaaacatca tcatttaatt ctgcaaattt tggtgcaaaa tctcctaatt gatctcgtcc
     4441 tgcggtttgt ttttctgcca tttctcttat tctcccttca cgactgttag gtgattcaac
     4501 tatggttcta aggcaacttt attttctatt gtttcttcgc atttcatttt aaatgtagtc
     4561 tttcagcctg tccaatgctt agtttattca gtcgatatgc tttttaagca tagttgctaa
     4621 cgcttttttt attttaaaaa aaacaagtta ttaaataagt ctttagttgg atgttttttt
     4681 gagatcaatc ttttatactt atgatgaact tacaaaattg tttgttttct gtcatatcaa
     4741 aaaatggcgc agttagttgc ttttctagta aagtatagtt aacaaagaac ctctaaggag
     4801 ttgatgaata atgaatattg ctgcctctcg aaaactgata aatttcatat ccattatcgg
     4861 attaggccta tcaatcgcgc tgacgattta ttttattaat ttaggtgttt tcaaagattt
     4921 gaatgcgtta agaggattag taggtgattc catcatttta ggaccgatta tttttgtctt
     4981 catccaaatc ctgcaagtag ttattccaat cattcctgga gggatcagta ctgcagctgg
     5041 tgtcctgata tttggccctt atgctggatt tatctataac tatattggaa tctgcattgg
     5101 ttcgattatc atttttctgc tagggcgtcg ttatggaaag ccattcatac tttccatgat
     5161 tagcgataag acatataaca aatatattgg ctggctggat aatcaaaacc gttttgagaa
     5221 gctgtttgct ctagctattt ttcttccagt tgctcctgac gatgcgttat gtttgatggc
     5281 tggattgaca aacatgtcag tgaaacgata tacactaatc attttgattg ctaaaccact
     5341 gtcgattttc ttatatagta tggccttgat ttatggaggt caatatctaa gtggtcttct
     5401 tggataatat ttattttgta aaattagtca ttgattgaca atgt
//
LOCUS       DAZUJR010000126         5441 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.130, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000126 DAZUJR010000000
VERSION     DAZUJR010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5441)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5441)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5441
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.130"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..476
                     /locus_tag="ACG804_002697"
     CDS             <1..476
                     /locus_tag="ACG804_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HFS4833568.1"
                     /translation="ELLFFSEYIDNPLIQEYILGEEYTIDVCLNFDSTPVSIVPRKRI
                     ATRGGEILKGQIIKDRELIETTKKMLEKLNAIGHITIQCIKNEKGIFYLEINARYGGG
                     APISIKSGANSPEYIIKMIDSKKNLRYRENYLDKMIALRYDQAIYLDEKGNVYND"
     gene            469..1164
                     /locus_tag="ACG804_002698"
     CDS             469..1164
                     /locus_tag="ACG804_002698"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFS4833569.1"
                     /translation="MIKAVIFDLDDTLVSEYDYVKSGYKCVARRLAVQKIFPATFDEI
                     YRVLLDLFAEDSKNVFNRLYDYFEIPYSKKEIKELVNVYREHKPDINFLENADTLLTE
                     LRSRGYKLGIITDGYAITQRNKLDALKVDYLVDYICITDELGRELWKPHPISYLLLLE
                     KFNLKAQECIYIGDNELKDFITAKSIGMQTIKIERVNGIYRESSLKFKRFYQADKKIR
                     SLWEIKNFLGVIS"
     gene            1161..2279
                     /locus_tag="ACG804_002699"
     CDS             1161..2279
                     /locus_tag="ACG804_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HFS4833570.1"
                     /translation="MKSKRILLASPHMSEEGYEKEYVKEAFDTNWVAPLGANVNGFEK
                     ELAEYVGASHAAALSSGTAAIHLALKAAGVGKDDIVICQSLTFSATANPILYQGAIPV
                     FVDSDYETWNMKPEHLRTALEKYPNTKAVLVVHLYGLSANLDEITKICKEYDVTLIED
                     AAESLGTTYKGKYTGTFGDYGIYSFNGNKIITTSGGGMLVSNDKEKVEKVRFWATQSR
                     EKARHYQHNEIGYNYRMSNIVAGIGRGQLKVLNERIEKKRYIHSFYKKELSKLSNIQF
                     MPENNWNEPNYWLSVITIKGINANHLIDELDKNNIEARPVWKPMHLQPVFKNYDYIGD
                     DVAETLFDLGVCLPSDTKMTDEDLKYVVSTIKRVINDA"
     gene            2269..2889
                     /locus_tag="ACG804_002700"
     CDS             2269..2889
                     /locus_tag="ACG804_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HFS4833571.1"
                     /translation="MMRKKTFYQLFGKRILDILLSGIALIVLSPIILIVGFLVRIKLG
                     SPIIFKQERPGKSEKIFSMYKFRTMTDERDHNGEYLPDEIRLTKFGKMLRATSLDELP
                     ELWNILKGDMSIVGPRPLLVEYLPLYSEKQRKRHNVRPGLTGLAQVNGRNAISWEEKF
                     DLDVYYVDKISFFNDLIIIIQTCKKVIKKENINTINNNIPEKFKGS"
     gene            3085..4185
                     /locus_tag="ACG804_002701"
     CDS             3085..4185
                     /locus_tag="ACG804_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFS4833572.1"
                     /translation="MAKYYNKKILIMANNDDGLYRFRGMLIKNLVDQGNEVIVSLPKG
                     KNIPKLIELGCQIIETPIDRRGINPKTDFKLFFNYCNILKKIKPDMVIAYTIKPNIYG
                     GLACRLRKVSYALNITGLGTAFQKKGVLKSLIVFLYRLAAKKSKVIFFENFENMKTFQ
                     TLQIAKQSKYKLLNGAGVDVEHFSYLEYPKDEQVHFLFIGRIMKEKGVDELFEAMKNL
                     YSEEKNCVLDVLGYFEEDYGIKIEKYEKEGWLKYHGYQSDIRPFVERAHCFVLPSWHE
                     GMANTNLESAASGRPIITSDIPGCKEAVIESKSGYLCERKNSCSLYNSMNKFLKLSYE
                     QRINMGKMGRNYMIKKFNKKKVVDETIKSLFS"
     gene            4192..4587
                     /locus_tag="ACG804_002702"
     CDS             4192..4587
                     /locus_tag="ACG804_002702"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFS4833573.1"
                     /translation="MFCKVCDRKEGFCGFRIDIKELAKVSDIFLFTTLQEGMPRSMME
                     AMASGLPCIASKIRGNVDLLVEGKGGYLVPAKDAELVAECLRELINNKSLRKYMGNEN
                     LSRIKEFEVSIVKKRIKEIYEEVIGESVK"
     gene            4584..>5441
                     /locus_tag="ACG804_002703"
     CDS             4584..>5441
                     /locus_tag="ACG804_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFS4833574.1"
                     /translation="MKNPMFSIIVPIYCVEKYLKDCLDSIRNQTFKNFEAILVDDGSP
                     DECPEICDYYSQIDGRLKVIHKKNGGIIDARKTGVTSAMGEYIVFLDGDDWLANTYLE
                     KYAEVITKYNPDIICSGYFASRSNKIRKRELSCSFGYYDKDKIINLIYPKLIEDEHGE
                     YFRPQLWAKAFRTTLYKEQQQVSGQVSVGEDHACTKPCIYHANSIYMMEKCLYYYRIN
                     ENSITKKPQPYYWEGPKAIGEHFEKQIDMNKYDFQDQVYRNVTHNLFNVAVSQFNKQD
                     KYLNIKKDII"
BASE COUNT         2118 a          635 c         1037 g         1651 t
ORIGIN      
        1 aagaattgtt gttttttagt gaatatatag ataatcctct tattcaagag tatattttag
       61 gtgaagaata tactatagat gtttgcttaa actttgattc gacaccagta agtattgttc
      121 ctagaaaaag aatagcaact agaggtgggg aaatactgaa gggtcagatt attaaagata
      181 gagaactaat tgagactacg aaaaagatgt tggaaaaatt aaatgcaatc ggacatatta
      241 ctattcaatg tataaaaaac gaaaagggaa tattttattt agaaataaat gcaagatacg
      301 gtggaggagc ccccattagc attaaatcag gagctaattc ccctgaatat attataaaga
      361 tgatagattc aaaaaaaaat ttgagataca gagaaaatta tttagataaa atgatagcac
      421 tgagatatga tcaagcgatt tatttagatg aaaaaggaaa tgtatataat gattaaagcg
      481 gtgatctttg atttagatga cactcttgtg tctgaatatg attatgtaaa aagtggatac
      541 aaatgtgtag ctagaagatt agcagtgcaa aaaattttcc cggctacttt tgacgaaata
      601 tatagagtcc ttttagatct ttttgctgaa gatagtaaaa atgtatttaa tcgtctatat
      661 gactattttg aaattcctta tagtaaaaaa gaaattaaag aactggtaaa tgtatatcga
      721 gaacacaaac cagacataaa ttttttagaa aatgcagata ctttattaac ggaattaaga
      781 agtagaggat acaagctggg gattattaca gatgggtatg ctataaccca acgaaacaaa
      841 ttggatgctt tgaaagtaga ctatttggta gattatattt gtattactga cgaattaggc
      901 cgtgaattgt ggaaaccaca ccctatctca tatcttttat tgttagaaaa gtttaattta
      961 aaggcacaag agtgtatata tattggcgat aatgagttga aagattttat aactgccaaa
     1021 tcaataggaa tgcaaacaat taaaatagaa agagtaaatg gtatttacag agaaagcagt
     1081 ttgaagttca aaagatttta ccaagctgat aaaaaaatac gttcgttatg ggagataaaa
     1141 aattttttgg gagtgatttc atgaaaagta aaagaattct attagcttct ccacatatga
     1201 gtgaagaagg atatgaaaaa gagtatgtaa aagaagcatt tgatacaaat tgggttgctc
     1261 ctttaggtgc gaatgtgaat ggatttgaga aagaattagc agaatacgtg ggagctagtc
     1321 atgctgccgc attatcttct ggaacagcag ctatacattt agctttgaaa gcggctgggg
     1381 tcggtaaaga tgacatagtg atttgtcagt ccttgacgtt ctcagctact gctaatccaa
     1441 ttctctatca aggagctata cctgtatttg ttgatagtga ttacgaaact tggaatatga
     1501 aacctgaaca tttgcgaaca gcactagaaa aatatcctaa cacaaaggct gtattagtag
     1561 tacatttgta cggtttatca gctaatttag acgaaattac taaaatatgc aaagaatacg
     1621 atgttactct aattgaagat gctgcagaat cattaggaac aacatataaa ggaaaatata
     1681 ctggtacatt tggcgactat ggaatttatt cttttaatgg aaataagata atcacaactt
     1741 caggtggcgg aatgcttgta tccaatgaca aagaaaaggt ggaaaaagtg agattttggg
     1801 ctacgcaatc tcgtgagaag gcacgccatt atcaacacaa tgaaattggc tataattatc
     1861 gaatgagcaa tatcgttgct ggtatcggtc gaggacaatt gaaagtatta aatgaaagaa
     1921 ttgagaaaaa acgatatatt catagttttt ataaaaaaga attgtctaaa ttgtcaaata
     1981 tacaattcat gccagaaaat aattggaatg aaccgaatta ttggttaagt gtcataacaa
     2041 taaagggaat aaatgcgaat catcttattg atgagttaga caaaaataat atagaagccc
     2101 gcccagtatg gaaacctatg catttacaac ctgtttttaa aaattatgat tatattggcg
     2161 atgatgtagc agaaacttta tttgacttag gagtatgttt accatcagat acaaagatga
     2221 cagatgaaga tttaaaatat gtagtatcta cgattaaaag agtgatcaat gatgcgtaaa
     2281 aaaactttct atcagctttt tgggaaaaga attttagata tcctattgtc aggaattgct
     2341 ctcatcgttt tatcgccgat aatcttaatt gtaggttttt tagtaagaat taaacttggt
     2401 tctccaatta tcttcaaaca agaacgacca ggaaaaagtg aaaaaatttt ttccatgtat
     2461 aaatttcgta caatgactga cgaaagagac cacaatggag aatatttacc tgatgaaatt
     2521 cgactaacta aatttgggaa aatgcttaga gcaacaagtc tggatgagct acccgaactt
     2581 tggaatattt tgaaaggtga tatgtcgatc gtaggacctc gtccattatt agtggagtat
     2641 ttgccactat atagtgagaa gcaacggaaa agacacaacg taagaccagg attaactgga
     2701 ctggctcagg tcaatggaag aaatgctatt agttgggaag aaaagtttga tttagatgtt
     2761 tattatgttg ataaaattag tttctttaat gatcttatta ttataattca gacatgtaaa
     2821 aaagtaatca agaaagagaa tattaataca atcaataaca atatcccaga aaaatttaaa
     2881 gggagttaaa tacagcagct taatgcaagt tttgtgactt gcattatatt taggtataaa
     2941 tcaaagcgag tatattagaa ttatataaca tatgttaaaa aaacgtatag ctaataaaag
     3001 tatgatttta aaaatttgtg tagagtttta aatatactgt ttcaatacga gaaaattata
     3061 aaaaagtata aggaaaagag agttatggca aagtattata ataaaaaaat tcttataatg
     3121 gcaaacaacg atgatggtct ttaccgtttt cgaggaatgc tcataaaaaa cttagtagat
     3181 caaggtaatg aagttattgt atctcttcca aagggcaaga atattcctaa attaattgaa
     3241 cttggatgtc aaattattga aactccaata gatagaagag gaattaatcc aaaaactgac
     3301 tttaaactat tttttaacta ttgtaatatt ttgaaaaaaa taaagccaga tatggtcatt
     3361 gcttatacta tcaaaccaaa tatatacggt ggattggcat gtcggttaag aaaggtttct
     3421 tatgcattaa atataaccgg attaggaacg gcatttcaaa aaaagggggt tttgaaaagt
     3481 cttattgtat ttttgtatag attagcagct aaaaaatcta aggtcatatt tttcgaaaat
     3541 tttgaaaata tgaaaacatt tcagacttta caaattgcta aacaaagtaa atacaagcta
     3601 ttaaacggtg caggagtaga tgtagaacac tttagttatt tagaatatcc taaagatgag
     3661 caagttcatt ttttatttat tggaagaatt atgaaagaga aaggtgtaga tgaacttttt
     3721 gaagcaatga aaaacttata tagtgaagag aaaaattgtg tacttgatgt ccttgggtat
     3781 tttgaagaag attacggcat aaaaattgaa aaatacgaaa aagagggatg gttaaaatat
     3841 catggatatc aatctgatat tcgtcccttt gtagaaagag cacattgctt tgttttgcct
     3901 agttggcacg aaggaatggc aaatactaac cttgaatcag cagcatcagg gagaccaatt
     3961 attacaagtg atatcccagg gtgtaaagaa gcagttattg aatcgaagtc tggttattta
     4021 tgtgaaagaa aaaatagttg tagtctctat aattcgatga ataaatttct aaaattatca
     4081 tatgagcagc gcattaacat gggaaaaatg gggagaaatt atatgattaa aaaatttaat
     4141 aagaagaaag ttgtcgatga aacaattaaa tcattattta gttaaaaaga tatgttttgc
     4201 aaagtatgtg atagaaaaga gggattctgt ggcttcagaa tagatatcaa agaattggca
     4261 aaagtttctg atattttttt atttactaca ttacaagaag gaatgccaag atctatgatg
     4321 gaagctatgg caagtggatt gccatgtata gcaagtaaaa tccgaggtaa tgtagacctt
     4381 ttagtggaag gaaaaggtgg atatcttgtt ccagctaaag atgcagaatt agtagcagag
     4441 tgtttgagag aactaatcaa taataaatct cttagaaagt atatgggaaa tgagaacctt
     4501 tccagaatta aagaattcga ggttagtatc gtaaaaaaaa gaatcaaaga aatatatgaa
     4561 gaagttatag gtgagagtgt aaaatgaaaa atccaatgtt ttcaataata gtacctatct
     4621 attgcgttga aaaatatttg aaagattgct tagattcaat aagaaatcag acatttaaaa
     4681 attttgaagc aatactagtt gatgacggta gtcctgacga atgcccagaa atatgtgact
     4741 attattccca aatagatgga cgtttaaaag taattcataa gaaaaacggt ggaataatag
     4801 atgcacggaa aacaggagtc actagtgcta tgggagagta tatagttttt ctagatggtg
     4861 atgattggct tgcaaatact tatttagaaa aatatgcgga agtaattact aagtacaatc
     4921 cagatataat atgtagtggg tattttgcat cacgttccaa caaaattaga aaaagagaat
     4981 tgtcttgctc gtttggatat tatgacaaag ataaaattat aaatttgatt tatcctaaat
     5041 taattgagga tgaacatgga gagtatttta gaccacaatt atgggcaaaa gcttttagaa
     5101 ctactctgta caaggaacaa caacaagtat ctgggcaagt tagtgttggt gaagatcatg
     5161 catgtacaaa accatgtatt taccatgcaa attcgatata tatgatggaa aaatgtttat
     5221 attattacag aataaacgaa aattctataa caaaaaaacc acaaccatat tattgggaag
     5281 gaccaaaggc tattggagag cattttgaaa agcagattga tatgaataag tatgattttc
     5341 aagatcaagt atatagaaat gttacacaca atttatttaa tgttgctgtt tcacaattta
     5401 ataaacagga caaatattta aatataaaaa aagatattat a
//
LOCUS       DAZUJR010000127         5343 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.131, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000127 DAZUJR010000000
VERSION     DAZUJR010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5343
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.131"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(62..286)
                     /locus_tag="ACG804_002704"
                     /pseudo
     CDS             complement(62..286)
                     /locus_tag="ACG804_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877485.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(840..926)
                     /locus_tag="ACG804_002705"
                     /pseudo
     CDS             complement(840..926)
                     /locus_tag="ACG804_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            2092..3132
                     /locus_tag="ACG804_002706"
     CDS             2092..3132
                     /locus_tag="ACG804_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HFS4833575.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
     gene            3956..4288
                     /gene="traE"
                     /locus_tag="ACG804_002707"
     CDS             3956..4288
                     /gene="traE"
                     /locus_tag="ACG804_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraE"
                     /protein_id="HFS4833576.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            4907..5248
                     /locus_tag="ACG804_002708"
     CDS             4907..5248
                     /locus_tag="ACG804_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 family protein"
                     /protein_id="HFS4833577.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT         1943 a          728 c          900 g         1772 t
ORIGIN      
        1 taggtatttt tattatatat agatttaaca tatgtcggtc ggttgattga tatagctaaa
       61 gttataactc aaccgaagcc gattcatcta cacgaataaa gttgcgagtg ttctcggcta
      121 attcataaaa attgttatgt gttccatata gcaatactgg aataacttta ttttcttgaa
      181 tctcataagc aactctatac acggtgaccg catacttaaa tccattagac caattacctg
      241 ataaacctcc agttttttgc tcttacttaa atggatcaat ggcaatttca tcacaaacct
      301 atagaggatg agtgacttct gcctaattac gttaaaaaat attgaaagta actctatgta
      361 gcaaaaaata tctagaattt catttcctca aaactgatcg atattgtatc taaaaatata
      421 tactacctaa aataggtagt atatattaaa atatgtgctt ttgttagaaa aatcaataca
      481 taaattatca tatctgtata tgtcatttag gtatttcagt tatgttataa tagttttgct
      541 gtctgctacc ccggcctaat ctggcaaggg gaggaggaga tataatgaaa tacctttttg
      601 attttgtttt tgcaatcaag ccacttgcag atgtagtgtg cagttacctc tgcaaatggc
      661 ttgattgcaa aattgccaaa aaagacagta agcctacccg ttaattctat aatatagaaa
      721 cgtaaaaaaa accccatcag cctgcacgct gatggggttt ggtgatataa tgaaatacct
      781 ctttgttact cataattata ccataattag tcacgaatgc aaccaataga aaaaactact
      841 tagaacggta gatcatcgct aataacaatg cattgtccac caaatggatt ttgtgaagca
      901 ttaaatacat tgttattaat tgtcgctgct tttaactagg cctctcccct tctattataa
      961 aagaagatat atatcatttc ttaattacct actaccttaa accaaaattt aagtactacc
     1021 taatttaagt agtacttaaa caatctaaaa aatagttatc ccaattgtta tgcttttata
     1081 atacgattat ttgtaacaaa atgaatatta tataattaaa cactaccata tttaggtagt
     1141 gtttaattat tagcaaaaca aaaaatattt attctattct cttaacttca actaagttat
     1201 gctgcacacc tttatataaa tcatatgcaa ctcattagct agacaaacta caagcatgta
     1261 gttttatctg ttaattatgt actacctaaa taaagtagtt tataattagc aagtatatat
     1321 atttaaaaat ttaagattaa tttttttatg acttgtacaa atttatctga tattctctta
     1381 ttaagaacta cctaatttgg gtagttctta ttttttacat tttaagtagt atttaattgc
     1441 aatttggtag tattttttta ttatcttatt cttagaacgg tagtacttaa tataaatata
     1501 ggtagtatct aatttaagta ttaatggtag tatctaaatt aacaggtagt atgtaactac
     1561 tttaaagtaa tttttttcag attaacacag tagtatctta ttaaataagt taattttaat
     1621 ggtagtacat aattattata tatatctgac attggtagta cttattgtat tttttagtag
     1681 tatataatct attgttttct agcctaaagc cttgtcttat aagaataata taatatatac
     1741 tactgaaata aggtagtata tattactagt aatggtagta tgttttatat gcataaggta
     1801 gttcttaatt tattttttgt tttgacactg gtagtactta attatcttta attttaaaac
     1861 taaattttat tcatacgttt ttctggtagt atttaattat aaataatatt tatttaaagt
     1921 agttcttaat gactttaaag gtagtacata attcatttta tttctgattt taggtagtat
     1981 ttaattaaaa aacagtttta atgcgtttgc attttttatt tatctttgct attttcgaaa
     2041 agagtaggta attttacata aataaaacaa cgtgaaagta gaggatctac aatgactgat
     2101 tttaaatttt ttaaggcgga tagagtttac aacgaattat tttatcaatt tccaaaagtc
     2161 tttattgttt ctgacgaata caaaaaaatg aaagattcaa ctaagattgc ctatatgctt
     2221 ttaaaagcaa gattagagat cgcaatcagc aaacggcaaa tcgatgaaga aggtaatgtt
     2281 tattttactt atacgacaaa tgaactatgt agagtattaa actgccaaaa acaaaaagcg
     2341 atagcaatca aaaaagagtt ggaatccttt ggtttattat tacaaaagca gatgggattt
     2401 aacaaacagt tagggaaaaa taatcctaat agactatatc tagcagaatt aaaagtctca
     2461 gaaaatgata tctacttact cgaaaaattt gatagagaga atagggaaaa cgttgataaa
     2521 tcagagggta tgaaaatcat acccaccctc gacgaaaaat cagacgctga atcccttggg
     2581 gctcaagagg gtatgaaaat cataccgtgc caaaacgttg ataaatcaga gggtatgaaa
     2641 atcataccag aacttaataa taatatatta gacactaata gacacaatat agacactgaa
     2701 aaagaccgcc tacaagatca attgttgtta gacaattttg agacaattat gacaaacgac
     2761 agcattgcta cgtttgtccc tgaacgagta ttaaatttga taaaaacatt ttcttcaagt
     2821 tacagtgaag ctcaaaaaac cgtccagact attcataatg caaagaaaaa agctgaaata
     2881 gaaagtgata tttcgatagt ttttgaagaa ctcgatagtt attatgtcaa tgcagaacaa
     2941 gaattataca cgacactgtt aaaagcctat caaaaattaa aaaccgaaaa agtcgaaaat
     3001 atccagaacc tgatttttgt ctatgtaaaa aattggttta tcgaaaaacc aatagctgct
     3061 aaagtatcaa gtgaaaaacg tttgaattat gcaagctccc caagcactat tacgaaagac
     3121 tggttagagt gaaactttac tgacaaagtg attgttgctt catggagtaa cattaaaatt
     3181 aaaaattttt tattattcta attatattac gaatattaca aaataatagc tattttaata
     3241 gaatttataa gttaaaatat tatgataaaa atcacaaacg tagcctttta cgtcataagt
     3301 gttaaaagaa ataattaatt tcaaatatag aaaagggaac gtatgtttgc atactccttt
     3361 tttttgagtt ataataatac gcgaagagag ataatttcat tatttaaaca agctaaaaat
     3421 cttgatatta cttcttttca ggcaatacga atattattcg cttacatttt ttgtataaat
     3481 ttaattgtct gctatgcttg tgatgaattg attttcgttt tgcacttttg gatgataaat
     3541 ttggacaatt gaaaatacaa aaaaaagaaa ggcggtatga actcggaagg ctggtaacct
     3601 tcgtcagcgt tcatacacgg cattaagatt tggcccttaa tgcgttaacc tttcagtgtt
     3661 acggtattac ccgcaatgga tttagtataa cagatattca aaagtgatac cacttttttt
     3721 ggctgtgtta aggttaaaaa tacgtgatat tacgatgaat ctatgcctaa gcataatgtt
     3781 ataaaaatgt ccgtgtggct ctttgccgta tgacgaacgc tgaaattaga gggaacgcat
     3841 gtttggatgc gttccctctt ttttgtttgt catgaacgaa aatcaattct ctatttttga
     3901 aaaataacaa gaaaaacttg ttaaaaatat ttaaagaaat tgggtggttt attttatgtc
     3961 atatacagga attttgagtc tcaaagatat ttgtcactac ggtaaacggt gtaccgctac
     4021 agagaaaatc acgaagaaac tatcaactgg ccaaagtaaa accgttgtgc agtgtaagaa
     4081 atatataatc cagaaagaca aagtctcaga ggaaatgatt tattacattg ggaaacaaaa
     4141 gcaaataatt ttaaaagatc ctatcccctt aaaagagcta tatccaacaa tcaaacatgt
     4201 ttatgaccaa aacggtgtac tgattggtcg aagaaaaaat ggagtcttgc gttgtaccgc
     4261 aaaagggatg gggcgtttga tcggctgaat tgatcattct cataacttgt attttatcgt
     4321 ttttcgcttg cttgaaaata ttgtcgagac ttctaaagga acttagagtc actagaaaaa
     4381 taaggagtag acttgatcta tcaacaattc ccttcgggga gtgacggggt aggttttaac
     4441 gattggtaac gtaaaaaatt ggtcaatcga gtaaatgcgc ttgtttggat agtggtgaaa
     4501 tgaatttgtg taaataataa gcgcagagta aacaagaggg aatttagaag ttagacaagt
     4561 tagaatagcg tctagattaa tcatgagcag ctactaaggg atctagactt tgacgcaaac
     4621 tcatggaata aggagtaggt cttctcgtaa tggggaggac gcacaagaaa ttgtgtcgtg
     4681 tgctgcagta catgtagata cttgcgagga cgttgattat tggatcaatc gagcatttac
     4741 cgctgtctac tagggtttct cgtttcggac gccataaacg agtcgaaatt ttttatgtat
     4801 ttttaagtaa acgaaaaacg ataaaatatg aacaagtcct gaataaagtg aaaaaattga
     4861 tataaaacat agagaaaatg aaatttacgt aatggaggaa tgacaaatga aaaattatga
     4921 tccgaatata cgattgggca cacatactat taaggtttct ttccaacgtt gggattacaa
     4981 aggatttgtg acgtttagaa ggggcggaaa ttgtaaagga ttagatgttt tagcattaga
     5041 cgaggatgat ttatacgatc aaacattgac tgataatcca attggattcg gcttgctacc
     5101 tgaagatgat gaaggtaatg aatggtttaa aatgacgctt atgaatgata atggagacga
     5161 attatctgtt gaagatactt ggtcatattt gagtgattat attgtcagct ttgaaatcat
     5221 tgaatttgta gcggataaag aagaataaaa actggaggaa taaattttac agataaaggc
     5281 ttagaaggag tcacgacgat taataaaaag gtagtattac cttaggcatt gagtaaggaa
     5341 ttt
//
LOCUS       DAZUJR010000128         5311 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.132, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000128 DAZUJR010000000
VERSION     DAZUJR010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5311
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.132"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(73..1221)
                     /gene="nagA"
                     /locus_tag="ACG804_002709"
     CDS             complement(73..1221)
                     /gene="nagA"
                     /locus_tag="ACG804_002709"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HFS4833578.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1297..2133)
                     /locus_tag="ACG804_002710"
     CDS             complement(1297..2133)
                     /locus_tag="ACG804_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4833579.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2317..3534)
                     /locus_tag="ACG804_002711"
     CDS             complement(2317..3534)
                     /locus_tag="ACG804_002711"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFS4833580.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(3683..3844)
                     /locus_tag="ACG804_002712"
     CDS             complement(3683..3844)
                     /locus_tag="ACG804_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833581.1"
                     /translation="MEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGIAMDWAA
                     NLWNDYHDN"
     gene            3917..4000
                     /locus_tag="ACG804_002713"
     tRNA            3917..4000
                     /locus_tag="ACG804_002713"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3951..3953,aa:Leu,seq:gag)
     gene            complement(4240..5311)
                     /locus_tag="ACG804_002714"
                     /pseudo
     CDS             complement(4240..5311)
                     /locus_tag="ACG804_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1653 a         1082 c          838 g         1738 t
ORIGIN      
        1 ttttactaga acacaaaaaa aaccttaaaa ccaaacttaa gaagtttagt tttaaggtta
       61 acttaaatta tattatgcgt ggaaacgttc cacgccatct agataagttg cttccaatgt
      121 catatcaggg ttcaatacga taaagtctgc atcgcgtcct tgagcgattt ttccacatgt
      181 atcatcgatt ttacagctga ttgctggaat cagactagcc atcatgactg cttgttctgg
      241 tgttgctaat ccccagtcta caacattttt aattgcttct ttcaatttca atatacttcc
      301 agctaagttg ccagattcta gacgtgctgt tccttctttt actactactg gaaattcgcc
      361 taaattgtaa tttccatcag gcatcccacc ggccatcata cagtctgtaa ttaatgcgac
      421 atgatcatgt cctgcttttt ccattaggat tcccgcagca tttggatgta catgatggcc
      481 atcacaaatc aattcagaaa agacatgttc taaagataat aacgcaccca ccatacctgg
      541 ttcgcgatga ttcaatccac gcataccatt gaaagcatgg acaaatacac ttgcgcctgc
      601 ttcaacagct ttttgcgctt cttctagtgt agcattactg tgtcctagag aaacaactac
      661 tccttcttca gtcacttgtt tgacaaactc ttctacacct tgacgttccg gtgctaaagc
      721 aatttttttg attaaaccac ctgaagcttc ttgccattca tggaaagtat ccaaatcagg
      781 atccccgaaa taacttgggt tttgtgcccc tttgtgttct tctgtgaaga aaggaccttc
      841 aaaatagatt cctttgattt tagctcctgg tgcttcctga tacattttgc cgattgtctc
      901 agctacatct tttaaacgtt ctttgcttga cgtcaatgtt gttggtaaaa atgaagtcac
      961 tccacaagat aacagacctt cagacatcac tttgatgcct tctgcatcat tatccattac
     1021 atcatgattc atatagccgt gaatatgtgt atctaccaaa ccaggagcaa tccatttgcc
     1081 gctttggtca atgatgttga cttctccctc aggtagttct ttggtgtatt caccaaaaag
     1141 tccatcggta atttcaagat agcctgcatg tttgacacct gacgctaaaa agaatttgtc
     1201 agcatagata aaagttctca ttctattctc tccctttgtt tttctacctc taaagtactc
     1261 ttatttagag aagaagtcaa gaatggtcta caccatttac aaattttttg aaatttgttt
     1321 cacagcttgt gctaagcctt catagaatgc tgctctttct ggttcttctt tacgcttgta
     1381 tattaagctt ttaagcacaa ataaatcatt gaggtaatag tagctattct tctcttgagc
     1441 ccaatagatt ccttgattca cctgttctaa cgcttcgtcg atttcatttt gatggaataa
     1501 gaaatttcca taattataaa aaatttgcga aaattcactt tttgatcgtt catcagctga
     1561 ttgatgcagc agttggatgc ttcgactcaa atagtagcgt gcttcagccg tttttcctgc
     1621 cacaccatat atttttccga tacaactaat cagttgtatt tctgtgtcag aaacatggat
     1681 tctttctttt tggctagagt agcttaatgc ttctttcaaa taataaaggg actgagagat
     1741 attttgacgc aacgtgaatt cgcaaacacc gagataataa taatagcgtt gaaagtcagt
     1801 tgcttgatac agattttcag aaatatcaga agattttagt acttgttcta acttccgata
     1861 atcacgtttt tggaaacaac tatccaacag ttcaaataat ttatcgtttg tccgagtagt
     1921 ttttcgagag agattcatca catgatcaat cgttacccct agccgttgac aaatctgcat
     1981 catcaccaat acattcggca gttcctcatt attttcgatc cgacttaata cactttgtga
     2041 acaaatatca tgcgaaagca ttttttgcgt cattttttgt tcttttcgaa tctctttaat
     2101 gatcgttcca aaggactcga ttaacgtttc cataagtatc ctccccaaaa tatgcgtatt
     2161 cgcattctat tcgtatttta ctttaggaag tcgcaaactt caagaaaaga cttgcaacta
     2221 aataatatac tttagttatt taagaaaact ccactagaaa gagagcctca gtgtgtttgt
     2281 ctgtggccct cctactgaaa aatttggttt ttaaaatcat ttttggcgat aggttgctag
     2341 gaattctctc attttcttag ctgtttgttt caaatcatcc attttaggaa gataaacgat
     2401 tcgaaaatga tctggctggt tccaattaaa tccaccacca tgtacaagta gaatatgatg
     2461 ttcatgtaaa aagtccaaaa cgaatttttc atcatccaaa atattgaatc gctttgtatc
     2521 aatttttggg aatatataaa aagcagcttt tggttttacg gctgaaagac caggaatatc
     2581 attgattgca ttatagatat attctctttg ttcatagatc cttccgcctg gcaggagcag
     2641 ctcatcgaca ctttgataac cgcctagcgc ggtttggata atttgctgag acaatacatt
     2701 ggaacacaaa cgcatggagg acaacatatt cagcccttct atatagcctt tgacgtgtga
     2761 cttatctcca cttaggacca tccagcctac tcgaaatcct gctacacgat gagatttgga
     2821 tagaccgttc agcgtaacaa cgaacaaatc aggcgctaat gtagcaatcg gaatatgttc
     2881 tagaccatcc atcactaagc gatcatagat ttcgtcggaa taaataatca ggttattttg
     2941 tcgagctact tcaacgattt cttctaataa ttcttttgga taaagtgccc cagtaggatt
     3001 attaggatta atgataacaa tagcttttgt ccgactcgtt atttttgatt tgatatcatc
     3061 aatatcagga taccattctg cctcttcatc gcaaatataa tgaacaggtg tgcctccagc
     3121 taatgcaata gaagccgtcc acaacggata gtccggcatt ggaaccagta cttcatctcc
     3181 attgtccagc aacccctgca tacacatcgt gatcaattcg ctcactccgt tgccggtgta
     3241 gatatcattg atcgtcacat tcggaaaatg tttcagttgg caatattgct caattgcttt
     3301 tctagcagaa aagatcccct tggaatctga gtagccttct gagtcacggg cattcatgat
     3361 caaatcacga atgacttcgt ttggtgcttc aaatccaaaa ggtgcgggat ttcccgtgtt
     3421 caattttaaa atactaatgc cctcttcttg catccgctcc gcttcttcta gaacgggacc
     3481 gcgaacatcg taactgacac cttctaattt gttggatttt tcaaattctc tcatcactta
     3541 gccaatccct catttcaaaa agttagaact ttccaaattt tttgttattt actatttcaa
     3601 tatcatactc catcctagaa aattttgcca cttatttagg aaaaacgtaa gtattaaaaa
     3661 aacacaaaca agcgttgaga acttaattgt catgatagtc attccataga ttcgctgccc
     3721 aatccattgc aattccacaa atgattccta gcataaaacc aagcaaaaaa cgtccgaatg
     3781 caagtccaat caatacacct aagatcattc ccagtcctga aaattctccg tcatatttct
     3841 ccatcttaat aagtcctccc atttttgagc ttgacaacta tgtaaaacct cgctatcatt
     3901 agtgtgttat tattacgcag atgtgttgga attggcagac aagcatgatt gagggtcatg
     3961 tgagcgttag ctcgtgtggg ttcgagtccc atcatctgca ctacaactcg tgaagttaat
     4021 tttgcttcac gagttttttt gtttgaacgt ttctttatgc cattatatac atatcactgt
     4081 atcctttaca aaaagaacgt acaatcatgt aaacagcctg aggtgagtat atgaaggtcg
     4141 gaaacaagct actcgtagaa acttgcaagt gttaaaacaa ttaatcgaaa aacgagtaaa
     4201 atccctcacc taatactaaa gcgagggatt ttttgtatat tatctgttta tcaccgttat
     4261 tataaaggta caaataccaa gcacggttaa tccaaattgc ataaattcat ttttttgtac
     4321 actcatgctt ttcattagct ctttaactgc cattagtact aagatggcga taacaacata
     4381 aagtatatag tacgtccgca ttccggaagc ccatactgtg ggagaaaatc ccataattaa
     4441 ccttgaacaa aatcccatta tcatcaaaat aactaaaaaa atagaagttt tcttattgtc
     4501 aaaacttaaa taaattccaa caattaaaca tagtaataat gccaagacta ctaaagtagc
     4561 tatccaagta cctggataaa aaagtgacag tttcgttcct aactctgtaa agagattatt
     4621 caggttacta ctactccaaa tcattgccct tttatttcca ttgacgtaag taaagctttg
     4681 acccattgta ttaccaaaat aaataatcag gtttaagaaa aacggtaatg cagtcaatat
     4741 acgcacataa tagttttgac atttcctata tgttagaagg aaaattaaga aaaatagcaa
     4801 taaaaataag atattcatgt ctaaaaaaac ggctttccaa atgatgaaat acctaaatct
     4861 aacttattaa gaaagttgaa atttttatat tcaggaaacc atttattaat ttcatgtgca
     4921 gcacgtaatg cattccctgg agttgtcaaa gagaaaatta attctgctaa gcttattatt
     4981 gaaaatactg ataacttata attatatcgt ccattgacaa tcaaatataa actaactata
     5041 cttgttagaa caaaaaaaca ggcgttgact tgttcttgat tagttaaaaa tatcaataaa
     5101 ggaatactta cccaatatat ttttctattt atttcttctc ctcttaagag ttgaaaaaac
     5161 ggataaaaag ttagtaaact aaatgctact ggccactgat agttcaaggt ggttgctctc
     5221 caaccggttt cccccattac tgtcaatggt attaaacagt atatagagca aaccaataat
     5281 aaatttttaa catttatttt ctcaaaaaca t
//
LOCUS       DAZUJR010000129         5207 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.133, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000129 DAZUJR010000000
VERSION     DAZUJR010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5207
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.133"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1368
                     /locus_tag="ACG804_002715"
     CDS             <1..1368
                     /locus_tag="ACG804_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833582.1"
                     /translation="SFYYGEKFFKKIDAAFLFSCLYTFATYRTVDIYYRSAIAEAIAL
                     TIIPAVLYYAYGLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSK
                     QIKNDIKFVVVNLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDS
                     IIQALNNDITTYTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFL
                     FQKTPISLLQFPWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIA
                     AKENYAKVIQSKHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGE
                     SWEKGKYKAADNNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVD
                     VNAGENKIEITTKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINK
                     KNENK"
     gene            1355..2989
                     /locus_tag="ACG804_002716"
     CDS             1355..2989
                     /locus_tag="ACG804_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-pyruvoyl-tetrahydropterin synthase-related
                     protein"
                     /protein_id="HFS4833583.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNL
                     PYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGV
                     ADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            3164..3997
                     /gene="msrA"
                     /locus_tag="ACG804_002717"
     CDS             3164..3997
                     /gene="msrA"
                     /locus_tag="ACG804_002717"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFS4833584.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQGERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            4077..5066
                     /locus_tag="ACG804_002718"
     CDS             4077..5066
                     /locus_tag="ACG804_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFS4833585.1"
                     /translation="MYIADSARYEKMEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQ
                     REILRGAFDMGITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMW
                     EGPYGEWGSRKSIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGK
                     ALYIGISNYNGEDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGA
                     ITFSPLAQGLLTNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQS
                     LAQMALAWNLRQKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
BASE COUNT         1825 a          806 c          951 g         1625 t
ORIGIN      
        1 agtttttatt atggagaaaa gttttttaaa aagatagatg ctgctttttt atttagttgt
       61 ttatatactt ttgcaactta tcgaacagtt gatatctatt atcgatccgc aattgcagaa
      121 gcaatcgctc ttacgattat cccagctgtt ttatattatg cttatggatt gatattcaat
      181 agagaaaaaa aagtcatcgc tttatctgtc agtataagtc tacttgtgta tactcatgtc
      241 ttaactacac tattgtgtag tgcattgatt gcttgtatga ttatagttcg tttgttttta
      301 agcaagcaaa taaaaaacga tataaaattt gtggtcgtga atttagtaaa ggctgttttt
      361 ttgacttgtg cattaactag ctatttttgg tatcctatgt tgcagcagat gaattatcaa
      421 gaaatacaca gtcccttcaa aacagatttg cagctagaag cactttctat ttcagatagt
      481 atcattcaag cgttaaataa cgatattaca acatacacta tggggttatt aggattggtt
      541 gcgttgattt ttcctttatt catactgaaa gaaatggaga aaaaagaaaa aatcatctat
      601 gttggcgtag tttctacatg ggtatgcgta actaatttat ttccatggtt tttgtttcaa
      661 aaaacaccga taagcttgct ccagtttcct tggcgtatct taggtatcca aatctttttt
      721 tcttcaatga tcataacgct tgtttttatg aaaaagacta tgaataaaaa atattcatgg
      781 ttaatcattg gcgctactgt ggtgtttcta ctcgtcacgt ctatagcagc aaaagaaaat
      841 tacgcaaaag ttatccaatc aaaacacggt catattgtta tcaatgaaga aacactccca
      901 cgttatacaa catcagatat gggaggatta tacgattacg ccccaacaga agcgataaaa
      961 gaaaggcctc acttagaaaa acatgaagta aaagtaggag aatcgtggga aaaagggaag
     1021 tataaagctg cagataataa cattacttac acagtggcaa gcaacaaaaa gcaaaaagtg
     1081 acagtaccag tatatgctta tttaggtaca caggtaaaag taaacggtaa agtcgtaaat
     1141 gactcttata aaaaacatgg cttagtgaat gtggatgtaa atgctggaga aaataagata
     1201 gaaattacaa caaaatatac tccaactgct ctcatggctt tatggatcag tattctgact
     1261 tattgtttag tggtgtattc aagttttaaa cgatttgcac ctaataagtt gaaagattct
     1321 cgatatgtga ctaaaaagga gataaacaag aagaatgaaa ataaataaaa aagtagtaat
     1381 attgagtgga ttaattatag ttagtagtat atattctttc atctttttca aaaatacaca
     1441 gagtatttat accactggag atctttcttt tcacttatct cgaatcaagg ggttatcgac
     1501 tatttttacc agtccgatta attatgagac attcaattat actggatatg gtgtaaatta
     1561 tttttatccc tttctgactt tttttccagc tgtaatgtta tattggatga caaaaaattt
     1621 gattgtaagc tatattattt acgtttggtt attgaacttg tgtacaacac tcgtagctta
     1681 tcattatggc gagcggtttt taaaacaaaa aaaagcggca tttttattta gttgtctcta
     1741 tattttctct gcttatcgga cagtagacat ctactatcgt tccgcaattg ccgaagctat
     1801 cgcaataaca cttgttatcc ctgtattatt ttatgcttat caaatcatct ctggaaaaga
     1861 agaaaagtat ccgtctgtaa agctagcatt gagtatgagt ttgctagtgt acagccatgt
     1921 actatcaaca ttaatgagta cagcattaat tatcattttt atttttattc gtttggtttc
     1981 taaaggtttc aagaatgcag attttattgc tatatttaaa aaattattta gtgcggcagg
     2041 aatgacattg gttctgacga gtgctttttg gtatccgatg tttgaacaaa tgctctacca
     2101 aaaaatcaac aaacctagcg tgacaaattt atatgctcat gcatctaatg tgttcgatag
     2161 tctgactgaa gctatgaaca acgacttaac tacttactca atgggactag ttggtctgtt
     2221 atctttatgt attcccctga ttttatttaa aaaattaaca aacatagaaa aaaagattta
     2281 ttatggtacg tgtttgactt ggctagctac aactagtttg gtgccatggt atcttctgca
     2341 aaatacgcca gccaaattgt tacaatttcc ttggcggatc ttaagcttgc aaataatatt
     2401 ctcttctctg atattaacga tgatattttt caaaaataga agatacaata agacaagaga
     2461 actattttat ttatttatga ctgttttgtt attaatcact ttaactgttt ctagtaaaaa
     2521 aaatttcaat caaaaaataa tttctcagcc gggacatatt gttgtaaaca aagaaacagt
     2581 agaggcgtat accactaaag gaatggatta ttttttatat gattattctc ctatcgcttc
     2641 attggagaat aaggagcata taataaaaca cgaagcaaag attggcagtc aatgggtaaa
     2701 ccttccttat aaaacaactg gtagttctat catatataga gtaactaatg agaagagcca
     2761 agtaatcaca cttcctgtat atgcttattt aggaacgaat gtagaaataa atcatcaacc
     2821 tgtaaaggag caggtgaatg ctaatggatt ggtacaaata agcggagtca aaggagttgc
     2881 tgatattaaa gtaagcacaa gttatacagt aacgactatt atttcttatc ttgttacatt
     2941 aactgcatat ttatgtttat tttttaaaat agttttccat aaaaggtaaa ttaacttttc
     3001 atttataaaa taaattgatt aaaaaggaga atctgtcgat aaggattctc tcttttttat
     3061 acgaaaaatc tgtaggggga tgaagtaatc gcttatttcc tcactttatg ataaattaca
     3121 gctaaagtca ctagcttgtc ttcttcggaa aggaggagaa tctatggatg aggaacaaat
     3181 attcattcaa acactttata atctgatttt gaatccgaat acacgagatt gggaacgaaa
     3241 agtattgatt cagacaaaga atgacataag agaaaatata tccgttaaag aacagttatc
     3301 aaaactagaa gcaacactac gtccattagc tatccgaatg aatctgacgc ctgatgtaat
     3361 ggacttttat ttattgatta cggaaggatt tgataaggag caaaaatatg acttttccaa
     3421 gcatgccatg caagatgctg actatcaaga acgtgcagta tttgcagggg gatgtttctg
     3481 gtgtatggtc gagccgtttg aatcgaaaaa agggatccta tctgttttgt caggatacac
     3541 gggcggacat gttgaaaaac caaattatga tcaagtaagt ggtggttaca caggtcatgt
     3601 ggaagctgtg gagatcattt atgacacaag agaaataagt tatagcgagt tgctgacaat
     3661 ctattggcaa attactgatc ccacagatac atttggacaa tttcaagata gagggaagca
     3721 atatcgtcca gtgatttttt atcaaggcga acgacaaaaa gaattagcgg aacaatcaaa
     3781 acagaaacta gacagttcag gaactttcca ccaaccaatc gtcacaaaaa tcgaaccagc
     3841 cggtacgttt tggccagcag aaaactatca tcagcaattt tacaaaaaac aaccgaaacg
     3901 ttataaaaaa atccagcaag cacgtaatca atttctgatc tatcaacgag taaaaaacaa
     3961 atggcaaaaa aatatacgaa aaaatcattt tgattaactc cttttcttta aaatgtagta
     4021 aactaaaaat agaaaaaaga aagcgtttta aaaagatttg atgaggagga gaaaaattgt
     4081 atattgcaga tagtgcacgt tatgaaaaaa tggaatatcg taaatccggt cattcaggtt
     4141 tgaaattacc gattttatct ctcggattat ggcaaaattt tggtgattat gatcctatcc
     4201 ataatcaaag agagatttta agaggcgcat tcgacatggg aattacccat ttcgaccttg
     4261 cgaataatta tggaggccct gctggagctg cagagaaaaa ctttgggcgt atttttagag
     4321 aagattttca agcctaccgt gatgaactga ttatttctag caaagcaggt tatcatatgt
     4381 gggaagggcc atatggggaa tggggctctc gtaaatccat catttcaagt tgtgaccaaa
     4441 gtctccaaag aatggggcta gattatgttg acatcttcta tcatcatcgc ccagaccctg
     4501 atacaccttt ggaagaaaca gcagaagctt tgatgcaact tgtaagacaa ggaaaagcat
     4561 tatatattgg tatatccaac tataatggag aagatacaaa aaaaatgact gaaattttaa
     4621 aaagaaagga agcaccgttc attattcatc agatgcgcta caatatgttt tctcgtgcac
     4681 tactagaaga cgatctatct ccagtattag aagaagaagg gctaggggca atcacgttca
     4741 gtccgcttgc tcaagggttg ctgacaaatc gttatctaca tggtattcct gaagattcta
     4801 gagcacatcg taaggaaata ccattccttt cagaagaaca agttggatca actctggaaa
     4861 aaatcaaagc actgcaaaca atcgccgtat cacgaggaca atcattagcg caaatggccc
     4921 ttgcatggaa tttgcgacaa aaatctgtta caagtgtact ggtcggagca agtcggttaa
     4981 gtcagttaca agaaagtgtt cgaatgatgg ataatttaga tttctcacca gaagaagaat
     5041 tgagaatcga ccaaattcta gaatagaaac gatgtaatca aactttttat ccatatatta
     5101 aaaaaaacaa aagatgacat caagaatcga atgaagatcg tctgttattg aacatcatat
     5161 tttttgtcgt tcaaaataaa aatgatcgaa ggctaggagt gaatttt
//
LOCUS       DAZUJR010000130         5199 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.134, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000130 DAZUJR010000000
VERSION     DAZUJR010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5199
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.134"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            25..696
                     /locus_tag="ACG804_002719"
     CDS             25..696
                     /locus_tag="ACG804_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFS4833586.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            755..1195
                     /locus_tag="ACG804_002720"
     CDS             755..1195
                     /locus_tag="ACG804_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833587.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            1207..1875
                     /locus_tag="ACG804_002721"
     CDS             1207..1875
                     /locus_tag="ACG804_002721"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HFS4833588.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            1939..2562
                     /locus_tag="ACG804_002722"
     CDS             1939..2562
                     /locus_tag="ACG804_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HFS4833589.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            2618..3004
                     /locus_tag="ACG804_002723"
     CDS             2618..3004
                     /locus_tag="ACG804_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HFS4833590.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            3217..4608
                     /locus_tag="ACG804_002724"
     CDS             3217..4608
                     /locus_tag="ACG804_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HFS4833591.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
BASE COUNT         1728 a          861 c         1095 g         1515 t
ORIGIN      
        1 aatgatgaaa aaagggggag aaaaatgaat tttttagttg ttttaaaaga tactctgatt
       61 gagcgatcta catttctata tgttcaattg caggaaaata aaacattgct gcatttttca
      121 ccagagttcc atctagaggg gctaacatta ggagaaatct atcaagcaga agggctgtcg
      181 gctgttttgc acttttttaa ggtagaattg gaattaccag taaaagatta tatcgagctt
      241 tctcttgaat cttgggatcg agcagtggtt gaactgtttc cagaaggttt aatgatcgat
      301 acaaacgatg ggaagatcca tctgactgca gcagaactgc aaaaacaaat gcgttatcaa
      361 atagatgacg aaaattcttt ttctattttt agacgtcagc aaaagattct aaaaagcttt
      421 ttaaaagtga tcagtaaaaa acggaatctg atcaaaacga cacagctgtt gaaaaaatat
      481 ccaggtctgc ttcacacgtc tattcaattt cctcaattga ttacgatgat ccatcgtttt
      541 atacgtatgc aacagctacc atctaagaag ctgtttcttc cattgacgga cacatttcga
      601 gtagtcaaca gagaagataa aaagaaagtg attgtgattg actttaccag aaatcggaat
      661 gtccttcacc aagttgcaat ggaaaaggcc aattaaggct ttttcttttt ggattttttt
      721 gtcataataa atattagatg atggaggaga taatatgatg caaacatggt tagaaaggct
      781 aatacgattt cagcagaact atcacaaact tatgcaggga agatatgcga aatttgatca
      841 gttgaatcgc ggtctattga tcgctgcgct tgtctttagt ttgctaagtc gttggttgcc
      901 ctatagaatc ggacaattgt tgttcatcgt ctttttcgga tggatgatat ttcgtttcct
      961 atcaaaaaaa atctacccca gactaaatga gaatcaacgt tatttgaaat atcttgatag
     1021 agtcaaagaa aaatatcatc agataaaaaa caaaaagcaa gtcaaaatgg atcgaaaaag
     1081 ttatactttt tttgagtgcc cgaattgtca tcaaaagcag cgtgcaccta aaggaaaagg
     1141 acgaatacgt gtgacatgca aaacatgtgg tataaaattc gaaacgaatg tttaagggag
     1201 aaaagaatga aattagtatt attacgtcat ggcgaaagcg aagcaaattt tgaaaattac
     1261 tggacaggat ggctagatgt cgccttaaca gaaaaaggaa aagaacaagc agcagttgcc
     1321 ggtcaaaaaa tgcttgaagc cggacttcaa ttcgatgccg tttatacctc tgttttgaaa
     1381 cgtgcgattc ttaccggaca agtcgcacta gaagaaatgg gtcagttatg gcttcctata
     1441 ataaaaacat ggcgtctaaa tgaacggcat tatggggatc ttgtgggtaa aaacaaagat
     1501 aagatgaaag aaatatacgg aaaagatcaa gtaaaaacat ggcgcagagg atatacggaa
     1561 gttccgccgt taaccgcaga aaatagattt gaccgcagat atgatcactt ggatccgcat
     1621 ttgatcccat acggagaaag tctggaaatg acagtgaatc ggatcattcc cttatggcaa
     1681 gatcatctag caccaaaact aaaagatcgg caagatttac tagttgtggg tcatggtaat
     1741 agcatccgag cactgacaaa atatttagaa gatgttcctg aagatcaaat ggatacgatc
     1801 gatatcccaa atgcacaacc aatccagtat acattagcag atgatttgac aattctggac
     1861 aaaaaaatac tttaaagaac acctttatct aaaagtgaga gatagaaaaa agaagcaaag
     1921 gaatggaaca aaaggaacat gaaaaattat atatgggact ttgatggtac attgtttgat
     1981 acgtatcccg caatggtaga tggtgcatgg caagcactaa aagattttgg tatcagtatg
     2041 gacaaaaaag aaatctactt caaaatgaaa aagtattcta ctagttattt gatcaatgaa
     2101 tcaaacttga atgccagaga gtttaatgaa ttatttcacc gatatgaaaa agaaagtacg
     2161 gaagtttccc gtccatttcc agaaacgaaa caagtactgg aaatgctaaa agacaacggc
     2221 ggtcgtcatt tcatcctgac ccaccgtttg acagaatcaa catggggcct gttaaaagaa
     2281 catcgattgg cacatctgat tgaggaagta gtagggatcg atcaggactt tcctcgtaaa
     2341 cctgatccag catctttaaa ttatttgatc gatacttttc atttagaaag aacagacacg
     2401 atgatgatcg gcgatcgtcg tttagatatc gaagcaggga aaaatgcagg agtcgctact
     2461 tgtctttacg acatcgatca ttttctgggt gagatcccgg cagattatgt ggtaggaaat
     2521 ctgaatgaaa tccttacctt gcagagcatc attaaaaagt agtatcccct ttcaaaggag
     2581 atatgttata attttcataa aggagtgata aaattatatg gaaatcagaa gacaaaaaga
     2641 agttgtagaa gcatttcatt atgatatgag attgccgaac caagaagtag aaacagattt
     2701 gaaagtaggc ttctcgcctt taaaagaaac gatcgaaaac tatccgaaag aacatagcat
     2761 cgtaggagca cgcttagagt tccgtttagt gtttgataca tatgttttat ctggaagtgt
     2821 gagtcagatc aatcatatcc tcaatcggaa aattgaaggt caaaatgatg tcacacaaga
     2881 agaagtggac gagctagtag caccgttatt cgatatcgta cgccgaatgt cttatgaggt
     2941 gacagagatc gccttagatc agcctggggt aaaattgaat tttcaatcag aaaaacaaga
     3001 atagacagta aaaacatacc tgcgatagat taaagctatc acaggtatgt ttttttatta
     3061 ctaattgtaa gcaaaaagaa tgtcatttcg ataaaaatcg tctaaaatat aaaagtcact
     3121 gaaaaaaatt ttttcaggag gatggttgaa gaatcattct cgggaacctt tacttccttc
     3181 gatggacttg tcattaataa tatgaggagg agaaaaatga caacactcat cacagtttta
     3241 gtggttctag tttttgcggc attattatat gtgttctatc gtatgcaaaa gcgccataca
     3301 aaattttcaa cacgcgtctt tacagcatta ggagttggta tcgtctttgg cggtctgctt
     3361 caattgatct ttggtgtaga cgacaaagtc gttactcaat caatggaatg gatcgggatt
     3421 gtaggtcaag gatatgtatc attcttgcaa atgctagtta tgcctttagt gtttatttcg
     3481 atcattggtg cattcacaaa aatgaaagtt tctgaaaagc tagggaaaat tagtgcgact
     3541 gtattgactt ctttacttgg aacaacagct attgcagcat tgatcggaat tggttcaaca
     3601 atgctgttcg gactccaagg agctaaattc acacaaggag ctgcagaaac agcacgaatc
     3661 tctgaactgg caacacgtca ggaaacagtt gaaaacttat cgattccaca gcagatttta
     3721 tcctttatcc ctaaaaacgt ttttgctgat ttagcaggta gtcgtgcaac aagtacgatt
     3781 ggagtcgtta ttttcgcggc atttgtcgga atcgcttatc taggcgtgaa aagaaaagcg
     3841 ccaaaagaag cagcattctt ttcagattta gtcgacagtc tgtataaaat cattatgcgg
     3901 atcgtgacgc ttgttttgcg tttgacacct tatggagtat ttgctttgat gacaaacgtt
     3961 ttggcaacaa gtgattttgc agctatcgtc aatttaggta aatttgtcgt tgcttcttac
     4021 gtagcattgc ttgctgtttt gattgtccac tcactgattt tgattggtgc aaaagtcaat
     4081 ccaatcaact atttcaaaaa agcctttccg gtattgagct ttgcgtttac ttcacgttca
     4141 agtgctggag ctttgccatt gaatatcgag actcagacaa aagctttagg agtagatgat
     4201 gcaacagcta atttctcagc aagttttggt ttgtctattg gacaaaacgg ctgtgctggc
     4261 gtttatccag ctatgttggc aacgatcgtc gcaccagcag ctggagtgaa tgtctttagt
     4321 ttggaattta ttttgatgct tgtggcaatt gtaacaatca gttcttttgg tgtagctgga
     4381 gtcggtgggg gcgcaacatt tgcttcactg atcgttttag gggcaatgaa cttgccagta
     4441 gcaatcgttg ggttagttat ctctgttgaa ccattaatcg atatggcacg tacagcagta
     4501 aacgtcagcg gtagcatggt agctggtatc gtgacaagtg cacgcatcaa agatttagat
     4561 cgcgatgtca tcaatgatga ttctaaagtg atcgatgtga atgcatagtc aaaaagaggt
     4621 tgtgatagaa gtggtcagct ttaagaaata agaagaagtt tcctaaaaat agtttctcaa
     4681 atttttgtga aatttcggct tatttccgag aagctacttc tgaaacaccg tgaataagag
     4741 gttgtgaaaa agctgccctg catcaagtaa taagaacagc caaacaaaaa tagttcctca
     4801 tattttacgt ttggttgagc ttattaccgc agatgcaagc ttttgaacac cgtttaagaa
     4861 agaggtcgtg agcctgccgt ttcactctga gtcacaaaga gcaatttcaa aaaatagctt
     4921 ctcatgtttg ttgaatattg tgtcttgtga ccgaggagtt gtcaggagaa caccgtttac
     4981 cagaggttgt gacttgtttt tagtcacgac ctcttttttt atttattcca tataaataca
     5041 cattatttat tccgaaaagt gaaagcgcaa ataacaaaaa caaccaactt atttattatt
     5101 aaagaaaagc gtatttaagt aggacgattc tgttgagagc tttcgtagat tttcccattt
     5161 tcctatggta aactgacaaa gttgagaatg ttagaacag
//
LOCUS       DAZUJR010000131         5137 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.135, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000131 DAZUJR010000000
VERSION     DAZUJR010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5137
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.135"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            102..1148
                     /locus_tag="ACG804_002725"
     CDS             102..1148
                     /locus_tag="ACG804_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFS4833592.1"
                     /translation="MSVKISVIVPCYNVEKYIDECINSLINQTLKDIEIILLNDGSTD
                     NTLAILKKYEKLDSRIKVYEHKNMGLGPTRNRGIKIANGEFLAFVDSDDFVSNTMFES
                     LYNCAIAENADIAIGEVGIFSDREIERVKIRKSLTNLKTIELATYNKKEFFKQFYFNR
                     LYSHNAWDKIYRRSLVLEFNLSFGDNKIIFAEDNWFQLQVFMTNTRICFVDKLCYYYR
                     QQNNSIMHKPKSNLVFRHGNMIADYEKLIRQNGNNIIDKKACMLVAFDVLIMEIFNQK
                     NVGGTCEDYKNALVSLKHHKILRENISNIVRMKAYELEPNMRKKLALVTISIMFNFKM
                     YKTAYNMLWRIYNR"
     gene            1162..2241
                     /locus_tag="ACG804_002726"
     CDS             1162..2241
                     /locus_tag="ACG804_002726"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFS4833593.1"
                     /translation="MRKLTFVIGIMGKGGAERVIANLANNFIQDNWEIDIITIYGNRQ
                     DYELNRKIQVHPIICKSSFRAFRPLERFKELRKKIREIQPDLVISFLADVNIHVIISL
                     LGVKQKLIVSERNDPQRNPEEPWIRKIRDFLYKNVDGIVFQTPDAKKYFSKINDKKVK
                     TIIIPNPIKENLPYYNKTTSSKKFITACRLDKQKNLPLMIDAIGKLIHEGYECELDIY
                     GEGGLKTELESYINHNGLTEFVHLKEFTNKIHEKMQNAAGFVISSDYEGISNSMLEAL
                     AIGVPVIATDCPVGGARMYLGDRNEIGHLVECNNLDKLTDAMRRVLLDRESVVRKAQK
                     GIKLRKELTSKNISNIWYEYLNQFF"
     gene            2260..3684
                     /gene="wzy"
                     /locus_tag="ACG804_002727"
     CDS             2260..3684
                     /gene="wzy"
                     /locus_tag="ACG804_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy"
                     /protein_id="HFS4833594.1"
                     /translation="MKEKINILMFSLTLVAFTIFCAFSLNQNYWLNWLGILIYLYAIC
                     TWHWRKGDSIFSLYTIFFTLFLLFSYGQCIMWAFGIGTDRGIGTTVVAYGTGIIPSES
                     DMIMVKWYSCISMFVFHIGALLFTRKTTLRKVSWYESGDADADRKFLFKIGCIISIIV
                     VPIVFVSKLLEVRIALVHGYNALYYGDYATQSGYLQIILYLFFPALICLLIGSNFSKV
                     ITRFVFIIFALYSLLGIMSGDRGSWLYSSIILIWAYTQYKGTFNYKKLIKWLILAVIG
                     IYILNVITKARDGGGLSKLTLKDFTSVFDSDDSPLVDSFFEMGGTMSIITFFLISGNG
                     IYPFANTYLTSLLGSISTRMLSMFGIKFVLLADWFSQDYLGITWGTGFSMIAEAYVNG
                     GYIGGIVYIFIIGIVIGKILSNSIDNQDIENHPMKMFLAITTANIIMGFPRAASYLIV
                     KNFVYGVLIILLINFFLQQFNKRL"
     gene            3730..>5137
                     /locus_tag="ACG804_002728"
     CDS             3730..>5137
                     /locus_tag="ACG804_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HFS4833595.1"
                     /translation="MERTARLKKNTIWALVFQITSIVCGMILLRLILTKYGSEVNGMI
                     SSINQFLQIISFLQLGVGAVMQSTLYKPLAEKDNLMISQILASGGKFYRQIAYILLVY
                     VGLLLAVYYVLVPNEFGRSYTMAMIATLSINSFAQYYFGIVNTLLLSADQKIYITYIA
                     QTIAFISNTVACALLISLNTEILMVKLITAIIYLACPIYYRWYVDRNYNIKRNVSYDK
                     EPIPQKWNGVAQHVASVVLDSTDVVVLSIFSNLIYVSIYNVYNLVIYGVKQLFMAMTN
                     GVQALLGELWVRKEIEVLYKTFAWFEWIVHTLTVFIFGCTGILIVPFIQVYTRGVTDA
                     NYNQLSFAALLVTANALHCLRTPYHVMIKAAGKYKETQNSFIIASLLNLGLSLILVKP
                     LGLVGVALGSLISITYHTLWSANYNSKYLLKWPMKKFYKQLFVNILTVVLSFGATSQL
                     KMMSITYLDWIVLAIKCAV"
BASE COUNT         1825 a          606 c          934 g         1772 t
ORIGIN      
        1 tataaagata attggaaagg aattagtgct aagtttgcat tgaaaaacaa atgggtattt
       61 ttaatttata tttataacaa attgataaag aggtaataat aatgtcagtt aagattagtg
      121 taattgtacc ttgttataat gttgaaaaat atattgatga gtgtataaat agtttgataa
      181 atcaaacatt gaaagatatt gagattattt tgttaaacga tggttcaaca gataatacgt
      241 tggcgatatt aaagaaatat gaaaagcttg attctagaat aaaagtttac gaacataaaa
      301 atatggggtt agggccaact agaaatcgag ggatcaaaat agctaatgga gaatttttgg
      361 cttttgtgga ttctgatgat tttgtttcca atactatgtt tgaaagttta tataattgtg
      421 caattgcaga gaatgcggac attgcaattg gagaagtagg cattttttct gatagagaaa
      481 tagaaagagt aaaaataaga aaaagtctaa cgaacttaaa aacaattgaa ttagcaacat
      541 ataacaagaa agaatttttt aagcaattct atttcaatcg tttatattca cataatgctt
      601 gggataagat atatagacgt agtttagtat tagagtttaa tttatcattt ggtgataaca
      661 aaataatttt tgcagaagat aattggtttc aattacaagt atttatgaca aatacaagaa
      721 tctgtttcgt agataaattg tgttattatt atcgccaaca aaataattct ataatgcata
      781 agccaaaaag taatttggtt tttagacatg gaaatatgat tgctgattat gaaaagttga
      841 taaggcaaaa tggaaacaac ataatagata aaaaagcttg tatgttggtt gcatttgatg
      901 tactaattat ggagattttt aatcaaaaaa acgttggtgg aacatgtgaa gattataaga
      961 atgcattagt ttctttgaaa catcataaaa tattgagaga aaatatttca aatatagtta
     1021 gaatgaaagc atatgaactt gaacctaata tgagaaagaa gttagccctt gtgaccatta
     1081 gtataatgtt taattttaaa atgtataaaa cagcgtataa tatgctctgg agaatatata
     1141 atcgataaag aggtaggaaa tatgaggaaa ttgacctttg tgataggaat tatgggaaaa
     1201 ggaggggcag aacgagtaat tgcgaatttg gcaaataatt ttattcaaga taactgggaa
     1261 attgatatta taactatata tgggaatcgg caagactatg aactgaatag aaaaatacag
     1321 gtacatccaa taatatgtaa aagttcgttt cgtgcattta gacctttgga acgctttaag
     1381 gaacttagga aaaaaataag ggaaatacag cctgatctgg ttatttcgtt ccttgctgat
     1441 gtaaatatcc atgtcattat ttcattgtta ggagtaaaac aaaaattaat tgtttctgaa
     1501 cgaaatgatc cacaacggaa tccagaagaa ccatggatta ggaaaattag agattttctt
     1561 tataaaaatg tagatggaat tgtttttcaa acaccagacg caaaaaaata ttttagtaag
     1621 atcaatgata aaaaagtaaa aacaattata attcccaacc caataaagga aaatttacct
     1681 tattataata aaactacaag tagtaaaaaa tttattactg catgtagatt ggataaacaa
     1741 aaaaatttgc ccttaatgat tgatgcaata ggaaaactta ttcatgaagg atatgagtgt
     1801 gaactggata tttatggaga agggggatta aaaaccgagc ttgaaagtta tatcaaccat
     1861 aatggattaa cagaatttgt tcatctaaaa gaatttacaa ataaaataca tgaaaagatg
     1921 caaaatgcgg caggatttgt aatttcttct gattatgaag gtatatctaa ttctatgtta
     1981 gaagcactgg ctattggagt gccagttatc gctacagatt gtccagtagg tggcgcaaga
     2041 atgtatttag gtgatagaaa tgaaataggt catcttgttg aatgtaataa tctagataag
     2101 ttaacagatg caatgcgtag ggtacttttg gatagagaaa gtgtggtaag aaaagcgcaa
     2161 aaaggaatta aactaagaaa agaactgaca tctaaaaata tttcaaatat atggtacgaa
     2221 tatttaaacc agttctttta accaaaagga ggatattgtg tgaaagaaaa aataaatata
     2281 ttgatgtttt cgttaacgtt agtcgcgttt acaatatttt gcgctttttc attaaatcag
     2341 aactattggc taaattggct tggaatattg atttacttat atgcaatctg tacatggcat
     2401 tggagaaaag gagattcaat attttcatta tacacgattt ttttcactct ttttttatta
     2461 tttagttatg ggcaatgcat tatgtgggca ttcggtattg gaacagatcg tggaatcggt
     2521 acaacagtag tagcttatgg tacggggatt attcctagtg aatcagatat gataatggta
     2581 aaatggtatt cttgtatttc tatgtttgta tttcacatag gagcactctt atttacgaga
     2641 aaaaccacac taagaaaagt tagttggtat gaatctggag atgctgatgc cgatagaaag
     2701 tttttattta aaatagggtg tatcatttct ataatagtag taccgatagt ttttgtttct
     2761 aaattactag aggtacgtat agcattagtc catggttata atgcattata ttatggtgat
     2821 tatgctacac aaagtggata tttacaaatt attctatatc ttttttttcc agccttaata
     2881 tgtttattaa ttggtagcaa cttttcaaaa gtaataacga gatttgtttt tattattttt
     2941 gctttatatt ctttattagg aattatgtca ggagacagag gaagttggtt gtatagctct
     3001 attatactca tatgggcata cactcaatat aaaggaacct ttaattataa aaaattaata
     3061 aagtggctta ttttagctgt tataggaata tatattctaa acgtaataac gaaagcacgt
     3121 gatggtggag gactaagtaa acttacttta aaagatttta catctgtatt tgattcagat
     3181 gattctcctt tagttgattc tttttttgaa atggggggga ctatgagtat tataactttt
     3241 ttcctaataa gtggtaatgg aatatatccc tttgctaata cttatttgac ctcactctta
     3301 ggctctatat caacaagaat gctatcaatg tttggaataa agtttgtttt attagctgat
     3361 tggttttctc aggattattt aggaatcact tgggggactg gattctcaat gattgcagaa
     3421 gcctatgtca atggtggata cattgggggt atagtctata tttttattat tggtatagtc
     3481 atcggtaaaa tcctttctaa tagtatagac aaccaagata ttgaaaatca tcctatgaag
     3541 atgtttttgg ctataactac agcaaatatt ataatgggtt ttcctagagc tgcttcatat
     3601 ttaattgtga aaaattttgt gtatggtgtt ttaattatat tgttgataaa ctttttccta
     3661 cagcaattta ataaacgtct ttaatattta agcttaataa aaagataaaa caagtcagga
     3721 gttgcaaaaa tggaaagaac tgctcggctc aaaaaaaaca ctatttgggc tctggtgttt
     3781 caaataactt ctattgtctg tggtatgatc ttgctacgtt tgatattaac aaagtacgga
     3841 tccgaggtta atggaatgat tagctctatt aaccaatttc tacaaattat ttctttttta
     3901 caattaggag taggcgctgt aatgcaatca actctataca aaccactagc agaaaaggat
     3961 aatttaatga taagtcaaat cttagcttct ggagggaagt tttatcggca aattgcatat
     4021 attctactag tatacgtggg tttgttactt gcagtctatt atgttctcgt tcctaatgaa
     4081 tttgggagat catatacaat ggcaatgatt gcaacattaa gtattaattc atttgctcaa
     4141 tattattttg gtattgttaa tactttgtta ttaagtgctg accagaaaat ttatattacg
     4201 tatattgcac agacaatagc atttatttct aatacagttg catgtgcttt attaattagt
     4261 ctgaacacag agatccttat ggtaaaactt attactgcta taatttatct tgcttgtcca
     4321 atatattata gatggtatgt ggatcgaaac tataatataa agaggaatgt gtcatatgat
     4381 aaggaaccga tccctcaaaa atggaatggg gttgcacaac acgtagcttc tgttgtacta
     4441 gatagtactg atgttgtagt gttatctata ttttctaacc tgatatatgt atctatatat
     4501 aatgtgtaca atttagtaat atacggagta aaacagctat tcatggctat gacaaatggc
     4561 gttcaggcct tactagggga actttgggtc agaaaagaaa tagaagttct ttacaaaaca
     4621 tttgcatggt tcgaatggat tgtacatact ttgacagttt ttatttttgg ctgtaccggt
     4681 atactaatcg ttccatttat tcaagtatat acaagaggag taacagatgc taattataat
     4741 caattatcat tcgcagcttt acttgtaact gctaacgcac ttcactgtct gcgtacacct
     4801 tatcatgtaa tgataaaagc agctggtaaa tataaagaaa ctcaaaatag ttttataatt
     4861 gcttctttgt taaatttagg tttatcatta attttggtta aaccactagg gctagttgga
     4921 gtagcattag gatctctaat ttcaatcaca tatcatacac tttggagtgc aaattataat
     4981 tcaaaatatt tgcttaaatg gccgatgaaa aaattctata aacagttatt tgtaaacatc
     5041 ttaactgtag ttctttcttt tggggcgaca tcacaattga aaatgatgtc aatcacatat
     5101 ttggattgga ttgttctcgc aattaaatgt gcagtta
//
LOCUS       DAZUJR010000132         5040 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.136, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000132 DAZUJR010000000
VERSION     DAZUJR010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5040
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.136"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(91..1176)
                     /gene="xerS"
                     /locus_tag="ACG804_002729"
     CDS             complement(91..1176)
                     /gene="xerS"
                     /locus_tag="ACG804_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HFS4833596.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLENNPMDQVATITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKKTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VVNINLEDLSLEKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHTSTNTTTLYTHIDNAATIDALNAL"
     gene            1525..1720
                     /locus_tag="ACG804_002730"
                     /pseudo
     CDS             1525..1720
                     /locus_tag="ACG804_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
     gene            complement(3252..3770)
                     /locus_tag="ACG804_002731"
     CDS             complement(3252..3770)
                     /locus_tag="ACG804_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HFS4833597.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
     gene            4137..4385
                     /locus_tag="ACG804_002732"
     CDS             4137..4385
                     /locus_tag="ACG804_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833598.1"
                     /translation="MVKLKMLYIGLQHRSFFDCALGKKYYEVKIDDDTFLTAHQMKQL
                     QKRNDQLEENLILKKRLPYSRLARRTIKGQDLPEDHPF"
     gene            4888..>5040
                     /locus_tag="ACG804_002733"
     CDS             4888..>5040
                     /locus_tag="ACG804_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFS4833599.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYELTASAFDKW
                     VKQSKTS"
BASE COUNT         1672 a          823 c          775 g         1770 t
ORIGIN      
        1 tataaaaatg ataatgaagc ttgcctttaa agttgggctt ttatctaatt ttagagacag
       61 gcttcattat tatactattt tttactacat ttacaaagcg ttcaaagcat caattgtagc
      121 tgcattgtct atatgagtat ataaagttgt tgtatttgta cttgtatgtc ccaattgttg
      181 ggcagttaat accaatgaat ttgtctgttg atagagtcta gtagccaaag tatgacgtaa
      241 tttatgtgga ctgacttgga ctctgaatcc ttttgaatat tttgctacca tccgttcgat
      301 tgcaataccg gatatacgct tggcttctcc ttgataaatt gctagaaata aagctttttc
      361 gttttctgtt actttgtatc gttctttccg aatagctaga taattagcta aatattccat
      421 tgcaaatgct gctatattta ctgcgtctct cttatttcct tttctagtta ctaccacatt
      481 attcttttct aaagataggt cctctaaatt aatatttaca acctcggaga gtcttaatcc
      541 agatcctaaa atcaatgcat tgatcgccag gtctctttct acatctcgtt gataatagat
      601 caaagctcgt ttgctcaaag tttttttata ttcattggca atataatcta gataattttg
      661 tgtatcttcg tctagaaata attttttctc gattgcgttt gcacgggcag ctaacgtagt
      721 tttatctgtg atagttgcta cttgatccat aggattattt tctaagtatg gttttcctaa
      781 aggattattg gaacttttcg aaagatattt aaatagaacc tttaatgctg tgatatttct
      841 attgatagta gaagtagata gacctaagtt attattatct ttgagcttag tttttgttgt
      901 ctcttttttt acattttcct ttgtgcgacg tttcaaatga gatttgtaca agtttagatc
      961 ataggcagtt aactgtctta tcgaggtgat tgaagtatcg ggaacgatag actcactcag
     1021 aagccattca taaaagagct tataattttt tagatattct aaagtagttc gaggtgattg
     1081 atctttatcc tcacgatctt gaacaaaatc ttttatataa tcgggcatat gaagtatgat
     1141 tgtatctatt ttttgatata tttctgtatt tttcatgtta ttcatccttt cgataagtag
     1201 gggagaggag tatctctata attggactat accaattata gagtgttttg tcaattggta
     1261 tactctgaaa tttattaatt tatttcaaaa aagcagataa ataggtatag atttaataat
     1321 ttaaaataaa tggtatacat gaataggaaa ggaaacagaa ggaggcaatc ttaatttttt
     1381 aaattgtcta aattatatag aaagaacaat ctttctatat aattagacat aagagagact
     1441 acggttgatt tgatattaac aagcgtatat gaatgtatat acaaataaaa aaggggaggg
     1501 agaagttaaa gaaaattcag agaagtgggg cactcagtag tattaacaat ttaaaaggaa
     1561 tttcttaaag aaaatgggtt gcatcctgga gatacaattt ttttagataa agaaaaaatt
     1621 caagcaacaa ttcaaaaaaa tcttaactgc tgagattgat gtagcaatat ctcaatcatc
     1681 aacaaagtac gatcctgcct ttcaaaagct tattgataaa tgtttattca ttataaaaat
     1741 aaaagaaaaa tttatgtcag cttttttcat caaagtggta atgataattc gtctattaat
     1801 tgtatttttt aggaaatatg gtataattgt tttaacgaaa aggtaattca tgatacacca
     1861 aaaaccacta gctggcgggc tagtggtttt cttttacgtt ctattcagat taacgggtag
     1921 gcttactgtc ttttttggca ataattttgc aatcaagcca tttacagatg taatgcgcgg
     1981 atacttctgc taagattgca aaaaacatat cgaaaaggta attcataata caacctcctc
     2041 cccttgccat aataggccgg ggtagcagac agcataaata ttataccata actgaaaatt
     2101 tcattttagt acatttcaat atattgatga accagcacaa taaaacatgc catgactaac
     2161 agaaaaaaac ttattaaacc agatataact tgtaaacatc caactatata gaaaacgtaa
     2221 attttctata tagttggatt aagataacga ctatttattt tatcatattt ttactatacc
     2281 ctatactttt acttggtata tttatgaata atcgcaaatt tacccctata ctactagttt
     2341 gtaagttaga ttaataaaaa tactaaagtt atttgttctt ttattaaata cacctacaac
     2401 ttataaattg atggtattta gataacacga aagaataaaa ataacagctg atagtaaagt
     2461 ttgttgacga ttgctactca atcgaaagtg agttagtgcg tatgaacttg cttctgaaaa
     2521 cttatgaaat gaaagacctt ttacatcttg cagaaatcgt tactgggatt aaactaagca
     2581 ataaaaacta atgttcccct cattctttga acttctacta tttgatttat ttattctgat
     2641 aaatgacgat ttcaccttca ggatcttcaa atcccgtata gaatttattt aagatctctt
     2701 cagtatcagt aataggatag gcgataggcc acataccctt tgatggttag aataaactgc
     2761 tcaaaatctg tatcgtatgt tggctttagc atattaacaa aggctatctc caaattataa
     2821 accataagcg ttgaatcgtt cttaacaatt tcaattcttc ctaacccaaa gtcagaagat
     2881 ataattaccg gacttgcctt acccttcatg tgggttgttg agattccata tttaaaggga
     2941 attgtcggta ctatcggcgg tctgaaaaac atcccaaaaa taaaaaaatc tttcccctgc
     3001 tagtctccta agtccctttg tagcggatat ggcaccataa tctcatttta tcgaagtgag
     3061 tcatggttta tctgttggcc aaccaaaatt gatacaatct aacgatgcac cctctacggc
     3121 attctagggg agtgcacttg cattcaccca ataaaaaccg gcagttagca aagaacttat
     3181 gtagtcgtat gttcttactg ttaacataca agaggtctcc tttccacaat tgcttagcag
     3241 taaacgggaa tttacaaagc taatctcttc cattttctta tctttgttct aaaagtccca
     3301 aatggagcaa ctgtatttac atgaataaat ttatatactt cccatacagc cgttttggtt
     3361 gcctcgtctg cccattttct tttgtgtgca gtgaatagat cttcatcact cattgaatca
     3421 atcatcatgt taatatcatc aatattacga ttgagaattt cctctaattc tttcaatggt
     3481 agatgtgcat aggtatttgt aaaccactta tataactctc ctaactgatt ccatttaaat
     3541 tgatcagaag gcgttttaac agataatcca tttctttcat cattttccca ttttagaatt
     3601 aaattcgtcc aaccaacttg atatgctaaa ttttcagcag gtgttctatc cacttcctca
     3661 actcttttat ccttcaattc ttcaggaata gtttcaaatt ctaaaatata tttagtataa
     3721 gtcctattta tttctttttt taattcttct ttatttttat atgttctcat tatattacct
     3781 ccataaattc ctaattgtct cctttaattc atctataatt tcatccacga tattttaatc
     3841 cgttctacaa tgcatatctg atatgcattg actgtctaac tcatatgtga atgatttata
     3901 aaatatccca acgtctcatc taaagaaatg ttgatcgtca gcaaggagct aaaaaatacg
     3961 aatatatttc ttttgtagta aaatcggact ggtttgcata tcattttctt cgtaaatatc
     4021 aaaatcatgt taactactat caattactaa taaaaactac cactttaagc gttaagaact
     4081 gttaagttta gttaagtgag gatagttcac aaaatccatt gttaaacttc acgaaagtgg
     4141 taaaactcaa aatgctttat ataggattac agcatcgctc tttcttcgat tgcgcgttgg
     4201 gtaaaaaata ttatgaagta aaaattgacg atgacacgtt ccttacggct catcagatga
     4261 aacagctaca aaaacgaaat gatcaactcg aagaaaattt aattctaaaa aagcgattgc
     4321 catattcacg cctcgctcga cgaactatta aaggtcaaga tttacctgaa gatcatcctt
     4381 tttaggaaat tgaagctttt tatgttgcac aatgcattta taatactaca atgatgtttt
     4441 caccagatat tcttctaggg tgcggtgtaa tgaaacagat acacttgcaa aagaaaattc
     4501 accgcgaatt tactaaaatt atgaataatt atgttaatct tccgaaattt ttttccaaaa
     4561 ttaagggatc aagctggtgt tatagattgt ttaaggttgg caaaaaaata acttcttttt
     4621 aaacaattat agaaaaccga tactctgtta agttggttga cacggtgtcg atttttatga
     4681 ctttcttatt ctgaaacttc actaacggac agtacctaaa aagtctatag tatggacgtt
     4741 tacgagtact attttatcaa aaatgctgct catttcaact tatatgtttt agtgaactac
     4801 ccccacttag cttggatagg ctacaattaa ctagacagaa aaattaaggt gtgtagacta
     4861 gaagaaaaca taccaggagg aatttttatg tctaagagaa cacgaagaac tttttcacaa
     4921 gaattcaagc aacaaatcgt caatctttac ttagctggaa agccacgtgt agaaatcatt
     4981 cgagaatatg aactaacggc ttcagcattt gacaaatggg taaagcaatc taaaacgagt
//
LOCUS       DAZUJR010000133         4956 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.137, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000133 DAZUJR010000000
VERSION     DAZUJR010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4956
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.137"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(55..828)
                     /locus_tag="ACG804_002734"
     CDS             complement(55..828)
                     /locus_tag="ACG804_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFS4833600.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMDNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            972..1322
                     /locus_tag="ACG804_002735"
     CDS             972..1322
                     /locus_tag="ACG804_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HFS4833601.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            1303..2019
                     /locus_tag="ACG804_002736"
     CDS             1303..2019
                     /locus_tag="ACG804_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HFS4833602.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAAVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            2019..3467
                     /locus_tag="ACG804_002737"
     CDS             2019..3467
                     /locus_tag="ACG804_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFS4833603.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(3537..4046)
                     /locus_tag="ACG804_002738"
     CDS             complement(3537..4046)
                     /locus_tag="ACG804_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833604.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(4036..4761)
                     /locus_tag="ACG804_002739"
     CDS             complement(4036..4761)
                     /locus_tag="ACG804_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833605.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHSQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWRLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
BASE COUNT         1703 a          843 c          998 g         1412 t
ORIGIN      
        1 ttaagaaaaa ataagcgatt ttcttaagaa aagaggtagc ttcaaaaaaa gatcttaaat
       61 cagatcaaaa tacttcaatg cgtggacaat tccgccttct gtatttttct ttgtgataaa
      121 ggtagaaagt tcttttaatc cgtcataggc gttgtccata gcgattttgt tgtcgcaagc
      181 ttccaacaag gcaaaatcat tcggaccatc gccaaatcca aaagtaggaa ctttttccag
      241 ctgaagttct ttttgcagac gtttgacacc tgcccctttt gagattcctt tcttcactgt
      301 atcgatcgag taaggaccat tccgataaaa agttagctca ggaaaatgtt cgtgatagta
      361 ttcgtcacct gattgagata agatcagcaa catatttact gtgttttctt taaagcctaa
      421 aggatcaatt tccggaacat ctgaatgaat gaagtcgtaa gcattgatca ttgtttggct
      481 atgaccggta caccagattt tctgatcgtt atagtaagaa agttcatgac cgttcaactg
      541 tacatgatca tacatttttt gacattcttc tgaagaaaat gtttgagaat agatttcttc
      601 gccgtctact cgaatgaaag aaccattcat ggtgaccgca gaagtaatgc ccgcatcttc
      661 catgatagag tggatttctg cttctgtacg tcctgtagcg atgacgggga gaacattgtt
      721 ttcttttaat gcgttcatag cttttgccac ttcgggtgtg atttttgatt tcgcatctag
      781 taatgttcca tcaagatcaa agaaagtgat tgcacgataa tttgacacaa ataaaactcc
      841 ttttttattg gaataagttt atcttaacaa agaatgaaca aaagacaaac ctttcgtgaa
      901 gaattcctga acatattggt tcagtcaaca atttagagta tactataaga agagaattta
      961 ggagggaaag aatgattttt ttcagtattg gtatcttatt cttaataatt ggcagtcttt
     1021 ttcggattct gccctcaaaa ggaaatctgc ctttttatgg gtatcattcg cctcttgccg
     1081 caaaaacaga cgctcattgg cggctggctc aaaagacaag cggaaactgg ttttttctta
     1141 tgggcttact gatggcattg atcggctatt atttaaagac atctgggcat acgaattatt
     1201 ttctgattga aatgcttctg ctagtatttc caattatgcc tatttttatt atgacagaaa
     1261 agaaattaca gaaatatgac ctggaaactg gagggaacga taatgaatat tttaatgatt
     1321 gaagataatc aatctgtttc tgaaatgatg cagatgtttt tcttaaatga aggttgggaa
     1381 gcaactttca agtatgatgg aaaagaaggg ctcgatgcct ttttagaaaa cccacaacat
     1441 tgggatatga ttacactaga cctgaatttg cccacactgg acggtatgct agtaggaaga
     1501 gagatccgca aagtttcaag tactgtgccg attatcatgc tgacagctag agattctgaa
     1561 agcgatcagg tgatcggctt agagatgggg gcagatgatt atgtcacaaa acctttcagt
     1621 cctctgacgc ttattgctcg aatgaaagct ttgcatcgcc gtagtgagtt ggcagaagca
     1681 agagaagaag cagcagtttc agatgatcat tttgatatcg agactagtca tttcaagatg
     1741 aatacgaaaa cacgagaagc gtatctggac aaccggccaa ttgaaggact gacgcctaaa
     1801 gagttcgatc tattgtttac tttagcaaaa aaaccacgtc aagtattctc tcgggagcag
     1861 ttgcttgaat tagtctggga ttatcagtac tttggtgatg aacggacagt ggacgcccat
     1921 atcaagaaat tacgacaaaa aatcgaaaag gtcggaccac aagtcatcca aactgtttgg
     1981 ggagtcggct acaaattcga tgattctggt gttgcctaat gcgttatttg tatcagcaac
     2041 tcttagcttt ttgcggaatg gtcgcgttga tcttattgat cgttggagtt tcttttacac
     2101 aactgacaaa acaaacgatt gaagaaaaca attaccagca actgtttgga tatgctgaat
     2161 cagttgaaaa gacaacgcaa acctatgccg atacgctccc gcagtttagt caagatcagg
     2221 cgtttcaaaa tgcattgctg ctgacagagc aagtactgac agaacaaaat gtgaacttta
     2281 tatttatcga taaaaacgaa cgtgtcattt atccgactaa tacagcttta ctgaatttta
     2341 ccttaacagc tgatcaatgg aaaaatctga ggaatggacg tcaagaaaaa ttcacatcga
     2401 ataaaaatat tttaggacaa gcacaggcga cctcttacgc acttgtgcca tttaatttga
     2461 atcatgaatt ctatggagca cttgtagtta gtcaacctgc gcgaaatatc gataacagcg
     2521 ttcgtccaat tacactgaac ctgttcaaag gatttatttt ttccagtatc gttgcagtta
     2581 ttgccagcta tgcttttgca gcattccaag ttaagcgtat caatcggtta aggaatgcga
     2641 cgaaagaagt gacgaatggt aattttgatg tacagctccc cgtacatgac aaagatgaat
     2701 ttgatgagtt agcagatgat ttcaataaaa tgacgaattc attgaaagaa tctcaagcag
     2761 aaattgaaga acaagaaaat cgtcgaagac aatttatggc agatgcttct cacgagatga
     2821 gaacacctct tacgacaatc aacggacttc tggaagggtt agaatacaat gcaatccctg
     2881 aaaatcagcg agaaaacgcg attaaattga tgaaaaatga aacagagcgt ctgatccgtt
     2941 tggtgaatga aaacttggat tatgaaaaaa tccgtacgaa tcaaatcagt atggtcatta
     3001 aaaaattcaa tggaacagaa acattgaaaa atattgttgc acagttagaa gctaaagcag
     3061 aagcagcagg agatacattg acattgaaag ccgttgatga tattgatgtt tacgctgatt
     3121 atgaccgatt tgtccaaatc atggtcaata ttattcaaaa cgcgatacag tttactgaaa
     3181 acggccaaat cacgattact ttagaaaaag gctatcttga aacgatcatc acgattgaag
     3241 atacgggaat tggaatgtct gaacaacaaa tgaaaagtat ctgggatcgt tattataaag
     3301 tagatccttc aagaaaaaat acaaaatatg gtgaatcagg attaggttta ccaatcgtgc
     3361 agcaacttgt acgcttgcat aaaggaaaat tagaagtaga aagcgaacta ggaaaaggaa
     3421 caaaattcgc tgttcgtttg cctgacgtag aaatcaaaaa agagtaaaaa acaagcggta
     3481 taaaagatca tgaatcgatc ttctataccg cttgttttta ctataaaatg attgatttag
     3541 cccgcgggct ctaaacgatc aatataagga ctttgagcaa tagtagcatc atgagtaaag
     3601 agtaagatac cttgattttc ttcatgagct aaataagaaa gcaagtggag tagctcttgg
     3661 atctccaata cactaagttc atcaaatgta tcttcaataa caatattgtt tcgcttggaa
     3721 agcaaggcat gaagtaattg cagctttact ttttcaaaag acgtcaactc agctgccgca
     3781 caattaagca aggaaggaga gatatcaagt ttttcttgat aggccaaacg atcttgtttg
     3841 atttcttttt ccggtacatc caacaggaca tggtctttaa gattcagata aggaaacatc
     3901 ggccaatttt tttggatgat cgcaaaatta tccagttttg caacaagaac ctcttttttc
     3961 aagtgctcca atattttatg ctgtttttcg agaggacaca aaataacggt caagtgttca
     4021 gcatgaatca aatattcagg tttcattacg tccaggcctc ctactttgca aatgatggat
     4081 aaaaaaagtg aaagggaata gactaagaat gagacagcat ccactgagcc caataagagt
     4141 ttgggcaaat cccttaagta tatctgtgaa aaaaagatca ttttggaaat cgatggtaaa
     4201 aaaagtctgt tgatccatcg gaattgtaag tccgcttacc gaagtcaaga tatcacggat
     4261 atctggcagt tcagtagtct ttaagacaag aaaattgatc ctttgaagaa gcgcttcata
     4321 aactgactgg aagctgacga tccacaataa aaccaagata caacaaagaa agagaggaaa
     4381 gaacagctgc cagaaaataa aaaggaataa tttggtttta gaaagaccag tcaggcgcca
     4441 attgatcaat tcctgcttgt tttgcctgac tgaatagtaa aagaaaaaga taaaaaggaa
     4501 ggcaaataga aaaaataaac tgaatatgcc ttttatataa aatcggctag ctaattctaa
     4561 agccggaaga agctctgtag atgcagaagc gccaataaat gaaagccgat cttggacttg
     4621 attggctaaa gccgattgcg aatggtaaag agtcaggcat gctatcaata aaaaagcaga
     4681 aaagcttgaa aataaacaat agagtattgt ctgctttttg taataaatta atcgagcagt
     4741 agcatagcgg attattttca tacttttcac ctctataaaa agtatagaaa atgaatatga
     4801 ataaagtatg aaattccttt agtgaaatca cgaattaaaa ccagaaaata ttttgtaaaa
     4861 agcaagaggt tgtgaagaag ctgccctatt ctattaccgt agatgcaagc ttttgaacac
     4921 tgtttattcg aaaagaggag cagcgacaat aatttt
//
LOCUS       DAZUJR010000134         4932 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.138, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000134 DAZUJR010000000
VERSION     DAZUJR010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4932
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.138"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            85..972
                     /locus_tag="ACG804_002740"
     CDS             85..972
                     /locus_tag="ACG804_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFS4833606.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1112..2038
                     /gene="cysK"
                     /locus_tag="ACG804_002741"
     CDS             1112..2038
                     /gene="cysK"
                     /locus_tag="ACG804_002741"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HFS4833607.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2274..2720
                     /locus_tag="ACG804_002742"
     CDS             2274..2720
                     /locus_tag="ACG804_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFS4833608.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2993..4345
                     /locus_tag="ACG804_002743"
     CDS             2993..4345
                     /locus_tag="ACG804_002743"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HFS4833609.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4516..4803
                     /locus_tag="ACG804_002744"
     CDS             4516..4803
                     /locus_tag="ACG804_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFS4833610.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT         1695 a          813 c         1030 g         1394 t
ORIGIN      
        1 aattaaaagt ataatttaat taattaagtt tgttttaaga agagaacttt ttattaagtt
       61 tttttatttt gaggaggaat ttgaatgcaa gagctgaaga cccgcagtgc ccggcaccat
      121 agacctaaaa gaaaaatggt gatcaataaa aaagcgattg ctcctttaat tggaacgagt
      181 cttttagttg ggccgatgat ggttacagcg gtaccgcaac atgttcatgc agatgaacaa
      241 ggatctcaaa cagtcgctga tcctcaagcg tttatcgatc aaatcggctg gtctgcgtca
      301 gaagttgctg caagtaatga cttgtatgct tcagtcatga tcgctcaagc gttgttggaa
      361 agtgcatatg gcacttccgg attagctagt gcgccaaatt ataatctatt cggtgtgaaa
      421 ggaagctata acggacaggt cgtttatatg gcaaccaaag aatatgtaaa cggacaatgg
      481 gtaacgatga atgagccatt ccgaaaatat tcttcttatt gggaatcctt ccaagaccat
      541 gcgaatgttc ttcgttcaac cagtttttcc acgggcgatt atcattatgc tggcgtgtgg
      601 aaaagcaata caacaagttt ttatgatgca acagcgtact tgacaggtcg ttatgctacc
      661 gatccaaatt atggggccaa attgaactca ttgattaata cttataattt aacccgtttt
      721 gatacgccat caacaggttc ggctacaaca accacaagta caacaacaac gactactacg
      781 acgacttcaa cgtcatcatc ttcaacaaca gatgtaaata caaataatgg tcagacatat
      841 acagtcgtgt caggtgatac gctatgggat attgcacaaa aatttggcat gtctgttgat
      901 gatctaatgg cgaaaaatgg catgtctatg tccagttatt ctttattagt tggtcaagaa
      961 ctaaacgttt gatttagata aaaaggcaaa gaaattacca tatatggtat atctttgtct
     1021 tttttttgct agtcaaagac gaatcactcg ccataaatga acagattgta ttatgataag
     1081 taagaagagc aaagacaagg aggaattgaa gatgacagct atctataact cagtcaccga
     1141 attgattggc aaaacgccaa tcgtcaaatt aaataaaatc gtaccagaag attcagcaga
     1201 tgtttttgta aagcttgagt tttttaatcc aggaggaagt gtaaaagatc gtattgcttt
     1261 aagtatgata gaaaaagcag aacacgatgg tctactgaaa ccaggtgata ctatcattga
     1321 acctacttct ggaaatacag gaatcggatt gtcgatggta ggagttgcaa aaggatataa
     1381 agtaatcatc gtgatgcctg agacgatgag tatcgaaaga cgtttattga tgaaagggta
     1441 cggcgcagag ttgattttga ctcctggtgc ggatggtatt tctggatcaa tcagagaagc
     1501 agaacgtttg gcaaaagaaa acggctactt tttaccatta caatttgaaa atgaagcaaa
     1561 tcctcttgtg catgagaaga cgactggtcc tgagatacat caagcatttg gagtaaatgg
     1621 cttggacgcg tttgttgcag gtatcggtac aggaggaacg atcactggcg ctggccgaga
     1681 attaaaacgt gtgtatccga aaatcgaatt aatcggggta gaaccagcag aatctgctat
     1741 tttagaaggg aaagaagcgg gacctcacaa aatccaagga atcggtacag gttttgttcc
     1801 taaaacactg gatacttctg tgtatgataa agtcctttct attagtggag acgaagcgat
     1861 ggaaacagct agagaagttg ggcgaaaaga agggatttta gtaggcatct catctggcgc
     1921 tgcaattgct gccgcgctaa aagtcgcaaa agaattagga aaaggcaaga aggtattagc
     1981 tgtggttccc gacaatggtg aacgttattt atctacagcc ctttaccaag agatataagg
     2041 cacttggttt ttctccagat aggtttatgt aaaaaacttt taaagatgaa aagaacacac
     2101 aaaaatttat gatgagaaaa attatttgaa tagagacgta gaatagtgaa cgcgactgtt
     2161 ttacgtcttt tttcattaaa atacaataaa attgaatttt cttttcatgt taagtggatt
     2221 ttaaaatgta aaaatagtat gataagacga gaataacaac gtggggtgtt tacatggaaa
     2281 ataagttagt cgaagaggtt atcgaaaagt taaaaaaaga gaacattcga atcacacctc
     2341 aacggtacgc ggttttagaa tatttgattg aacatcattc ccatccaacg gctgatgaga
     2401 tttataaagc acttgaacat cggtttccaa atatgagtgt tgcgactgtt tacaataacc
     2461 ttcgcttatt tacttcgatt ggatttgttc aagaaatgaa gtacggcgat gcttctagcc
     2521 gatttgattt cagttcaaag cgtcattatc atgtaatttg tgaaaactgc ggtaagattg
     2581 ttgattttca ttacccaggg cttgaagata tagaaatggc tgcaagcaga ctgactgatt
     2641 ttgagattaa tgaacatcgg ttggaattgt atggactctg tccggattgt aaagagtcag
     2701 caaaaaaggc gcaaatgtaa aaacagtttc tacaagtgtt atacctaaaa aaagctagct
     2761 gtgtaaaaaa aacgctagct tttttatttt tttgtctttt attcacaatc ttagatataa
     2821 aagtgaatat tattaaaata agaatcttgt agatattggg ttcttatgct tgaaaaggaa
     2881 tgaaactaca aacaaacctt tgtgaattca caagcattaa actgttgtat ccgttttatt
     2941 tctgttatag tagttttgtc gaaggacaaa atgttaatcg gagggaccat aaatgaaagt
     3001 agtagtaatt ggctgtactc atgcaggtac tgcagctgta aaaagtattt taaaaaatca
     3061 tccagaagca gaagtgacag tatatgaaag aaatgacaat atttctttct tatcttgcgg
     3121 tatcgcactt tatgtcggcg gagtagtaaa ggacccagca ggcttgttct actcaaatcc
     3181 tgaagaatta tcttcattag gagcaacagt taaaatggaa cacgatgtaa cagacgtcga
     3241 tacagaaaat aaaacagtaa cggcaaaaga tctgaaaaca ggagaaacag aaacggtttc
     3301 ttatgataaa ttagtgatga caactggttc atggcctatt atcccaccga ttagtggaat
     3361 cgatgcgaaa aatgtactcc tatgcaaaaa ctacaatcaa gcaaatgaaa ttattgcaca
     3421 agcgaaagaa gcaaaacgtg tagtaattgt tggtggtgga tatatcggta ttgaattagt
     3481 agaagctttt gtcgaatctg gaaaacaagt gacattgatt gatggattag atcgcatctt
     3541 gaataaatat ctagataaac cattcacaga tatcttagaa aaagaattga cagaccgcgg
     3601 tgttactctt gcgctaggcg aaaatgttac tgaatttatc acagatgaag aaggaaaagt
     3661 gaaacaagta gctacaccaa cagatacatt tgatacagat atggtcattt tatgtgtggg
     3721 cttccgtcca aatacaaaac tgatcgaagg aaaagtagat acactgccaa acggggcaat
     3781 caaagtgaat gaatacatgc agacaagtaa tccagacatt tttgcagctg gagactctgc
     3841 agtagtcaac tacaatccaa gtggcacgca aaactatatt cctttggcaa caaatgccgt
     3901 tcgtcaaggt ttgcttgtgg gaaataactt gacagatcat aaaatggcgt atcgtggtac
     3961 tcaaggaact tcaggacttt acctatttgg ctggacgatc ggttcgacag gtgtgaccaa
     4021 agaaagcgca actttgaacg atctagaagt ccaagcgact gtatttgaag ataattatcg
     4081 tccagagttc atgccaacta ctgaaaaagt aatgatggag ctagtctatg aaaaaggaac
     4141 gaatcgtatc gtaggtgctc agttcatgtc caaatacgac attacacaat cagcaaatac
     4201 catgtcttta gctgttcaaa ataaaatgac tgtagaagat ctcgcacttt cagatttctt
     4261 cttccaacca cattttgacc gcccatggaa ttacttgaac ctacttgcac aagcagcgct
     4321 aggcgaaatc gaaactgcac aataaagaaa aagggttgtg acacaatttt gtcacgaccc
     4381 tctgtctttt tttgtgaaaa gtacaattag ttgtctttct tcgaattttt tgtcacaata
     4441 agcagcaaag ataaagctgt tacataaaag aacaagcagc tttatttgat tttgaaaaga
     4501 aaggtgagaa agaagatgaa taaagaatat tttgtccaac aagatgcatt tttagaagat
     4561 tataaaagtg cttcgaagaa attaacgatc aatattgatg agttggcaga tcaagtactc
     4621 tctcagttga atgaaacgca agaggaatat tacacgatgc cagcaaatga cgccaaagat
     4681 aatgtttctc atcgttttcc tttcagtaga cgcatctact cagatgaaaa tgacggcaca
     4741 ttgaatacag agtacacata tgaaggtcag ccatatgtgc tagaaactga tgatgatctt
     4801 taaagacagt ttttgaaaag gccgctcatc cttaagtgat gacaaaaaat catcacaatt
     4861 accgatgact gtctctttac tatcttttaa tcagaaaaag gggttatgac aagctttgtc
     4921 aacccctttt tt
//
LOCUS       DAZUJR010000135         4899 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.139, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000135 DAZUJR010000000
VERSION     DAZUJR010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4899)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4899)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4899
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.139"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            55..741
                     /locus_tag="ACG804_002745"
     CDS             55..741
                     /locus_tag="ACG804_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HFS4833611.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            743..1687
                     /locus_tag="ACG804_002746"
     CDS             743..1687
                     /locus_tag="ACG804_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HFS4833612.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            1886..2530
                     /gene="pcp"
                     /locus_tag="ACG804_002747"
     CDS             1886..2530
                     /gene="pcp"
                     /locus_tag="ACG804_002747"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HFS4833613.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            2609..3886
                     /locus_tag="ACG804_002748"
     CDS             2609..3886
                     /locus_tag="ACG804_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833614.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            4144..>4899
                     /locus_tag="ACG804_002749"
     CDS             4144..>4899
                     /locus_tag="ACG804_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFS4833615.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEESTLRSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFSNRLTPYALTLIRLFPHPDFVLASTRTKIKNKLINETRKKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQK"
BASE COUNT         1583 a          887 c         1049 g         1380 t
ORIGIN      
        1 tatgtgtttt gctttataat taaaaaaata ttgtcatttt atggaggaaa atatatggaa
       61 aattatctta gccttttagg cgtcttgatt gttattctcg ggtttgcatt taaattagac
      121 tcgatattga tcgtaatggt tgctttagtt gttacagctt tgactggcgg tcttggcatt
      181 caaggaatgt tagaactttt aggtacaagt tttgtaaaca atcgcgggat ggcgattttt
      241 atcatcatta tgttggcaac aggaacgctt gaaagaaatg gtctgaaaga atcagcggct
      301 tccttgatca agcgattcaa gaaagtatct gctggtatga ttgtagatat ttatgggatc
      361 tttcgaatga tctttgcggc ttttaacgtg agttttggtg gagttgctgg atttgttcgt
      421 ccaatcattt taccgatggc attggggacc atcgaatcaa aagggttaga agtccatcct
      481 aagcatgaag aagaactaaa aggtatggct tcagctatgg aaaatgtctg ctggttcttt
      541 ggccaagtac tattcatcgg aggagcaggg gcgttgctag tccaatcaac actgaaagat
      601 ctaggatatg acgtaacatt gggacagctt gctttagtgg aagttccagt ggctatcacg
      661 gctttagttg tggcaagtgt ctacttctat cttaaagaaa agaaattagc gaagaaatat
      721 tatccaggaa aggggcaata agatggactt ttttacaaat cctgatattt tattaggcga
      781 taaattactg gagatccttt atatcgtgat gggactcgta ttgatttaca ctggagtaag
      841 aaatttaaca gataaaacca atcctcatcg ttatgggtca gcctttttct ggacggtctt
      901 aggggtagtt attgcaggag gaagatggct tccggcaatc gtgaacggtg gcttgatctt
      961 tgcgatgacc ataccagcaa ttgctaagaa agtcagcaaa ggagaaagcc ggcttccatc
     1021 aaaagaatat atggaaaaaa tgtcagacaa actaggaatg aaaattttta ttccagcttt
     1081 gagtatcggt gtctttgcga tcttgtttgc tctatttacc aatttaggtg ctttagtcgg
     1141 cgtgggcgtc ggtgtttttg cagccatgct aatcttgatg ttcttttctc gagataatcg
     1201 accaagtaca tttttagatg atgcagcaga tatgctgggc acagtagggc cgttaagcat
     1261 gttgccaatg cttttagctt ctctaggtgc ggtatttaca agcgctggag ttgggacagt
     1321 gatttccaat gcagtaggta cgatcgttcc agaaggaaat gtgaacatcg gcatcatcat
     1381 ttacgctctt ggcatggtga tatttacggt aatcatgggg aatgcatttg cggccatcac
     1441 cgtgatgacg gttgggatcg gtgcaccatt cgtatttagt catggagcga atccagcgtt
     1501 aataggaatg gttgcattga cttgcggttt ttgtgggacc ctgctgacac cgatggctgc
     1561 taacttcaat atcgtgcctg tagcgatgct ggagatgaaa gacaaatacg gagtgatcaa
     1621 aaaccagttg tttattgcgt tatttatgct agttttccaa attgcttata tgattctatt
     1681 taaataatag aagagagggg ttgtgacaga ataattgtcg caacctcttc taacattgta
     1741 gtggaacact atttttttat aagaatatat taagtttgat ctgttatgtt atttaaacta
     1801 ttgtttcctt tatttacgct gttcaaggaa aatggtatga taaaagataa ccatatgtta
     1861 aatcaatcgg acggaggaac aacagatgaa agtactagta acaggttttg atccatttgg
     1921 tggggacaaa gtgaatccag cctatgaagc agtaaaaaaa atgccagatg aaatcagcgg
     1981 tgctgaaatc atcaaagtgg aagtaccgac cgtattcgaa aaaagcagtc aagtagtcaa
     2041 agaagccatc caacagcacc aaccagatgt cgtgatctgt gtcggacaag caggtgggcg
     2101 gtcagcagtc tcgttcgaac gtgtcgcaat caatctagca gaagcaagaa tccctgataa
     2161 tgaaggaaat cagccattcg atacggcttt agaagaaaac ggtccagccg cttactttac
     2221 ctcattgcca atcaaagcaa tgacaaaaaa tgtacaagat catggtctac cagcgtacat
     2281 ctcttataca gcaggaacat ttgtctgcaa tgatatcatg tatcgtttgc ttcatttgat
     2341 cgaaacacaa ttcccggcaa ttcgaggtgg gttcatccac gtgccattct cacccgatca
     2401 agtgatcgat cgtccagtgg gtacgccttc tatgtcttta gaagacattg cttcttcttt
     2461 gacttatgca gttgaagcag cagtagaaaa taaagaagat atttccggaa atgccggaac
     2521 aactcactaa tttagcaaga aacactggct ggttgctaac gttatgttag tagccagctt
     2581 tttgtaatta gaaaggaaag aaacagccgt ggaagaatgg caatccgtct ttgaagaatg
     2641 gtttccaaaa gaaatcagca aaagctatcc catcaaaatt tctaaacaat acacaagcag
     2701 tcaacgttgg gagatctatg caaaattaac gaaaaaacag cgggaactag tcgataagca
     2761 ccgccgatat ctaatcagct ctcgttttat ggaagaacat tatttagctg caacagattg
     2821 ggtgttttct gacttcaaga tcaatccgtt ttttcgaaca aaacgaagcc agcaaaaatt
     2881 gtattgtgag tgtggtagag aattaaaagt gcaatacatc gttaaatcgc caaaaaccgg
     2941 aaagatccta aaactaggca tcaaccactt tgccgatcac ctgcatgtct ctccgacagt
     3001 ggcagcttcg atccatcagg gaatgacaaa agttgatctg gccttagacg aattattatg
     3061 gcttaagcag aagaatatcg attttcctga aggactatgg caaaaatact gttttgtctt
     3121 gtaccaaaat cgtcggatga aacagccata tttaccggat ataaaattag ctcagcggct
     3181 cgcagaattt cgccaagtag aaatgccgat ttacatagcg gattatcaag cattggaaaa
     3241 tgaaatcaag aaaataagtg aacacatcaa tgggcagtca aaaaagcgac agataaaaaa
     3301 agaactattt gacgactttg cagaagaatt agtaaaggat gtagaagaat tcttgatcaa
     3361 ctatcgcgca tttttacgta aagattggca atccatcgta tatgaagaag tgccagtaca
     3421 tcctaatgct tattttgaaa catttatttc cgtgttgaga aagacaaaac gtcaacgaac
     3481 accagaagtc actgctcaga tggaatattt tgcgaaaaac caacgattca tccaaccaaa
     3541 aatctatcta tttatttgga agcaatattg tcgctatggt tttacagaag ggttcttcga
     3601 cagcattcct cggatagtca gaaatggttt tttaaaagta ttgcgtaaag aacgagaagc
     3661 tatacaatct gctgataaga aagaccgtac agtctcaaaa gaaaaatggc aactagtagt
     3721 gaaagatatc caatctggaa atgtgcaaga gacaatcgac aaatggaaag gaaaacatta
     3781 tcgttttact gaagctcaga aacaagcgtt ggaatattat cagaagttag aagaatcact
     3841 gcgtttcaat gatgaggcaa gaaagtatct gaaggaatta ctataaaaaa catactaaga
     3901 ttagagggga acatcattga cgaatgatgt tctcctctat tttctatttt tagattatag
     3961 tgaagagtga aagaaagttc gaacaaagcc ttgaggacta cgagtcccta tcaaaaaccg
     4021 aacttcttta ctgtcatttt agaatcaggt ttacgtatgt tggggccatg agcccgtgta
     4081 taggaaattg gaatcgaaat gaagcagtaa agttctttca aaacttaaaa aggaggaaaa
     4141 caaatgcctt acattcttgc attagatgtt tcaatgggac acagctacag tgtcctatac
     4201 aaagacgaca cctgcttatt tgaagacgag attgaacaca ctcaaagagg atttcatgca
     4261 ttactcgaag agatccagca cttgcctgag cgtccattga ttgtttttga agcaacgggg
     4321 atttattcca gaccagtcga aaagttcttt caagatcatc acttttctta ctgtttgtta
     4381 aacccgttag aggcgaaaaa acagatggaa gaaagcacct tacgcagttg gaaaacagat
     4441 aaatcggatg cccaccggct cgcacagact catcttaaaa atcaacgtca gccaaaagaa
     4501 gtacaaagca atttttactt agagatgcgc gatttagccc gtttttatca agaaattgag
     4561 aagaaaatca ctcgtctgcg catggattta cacaactgcc ttcaattgac ttttccagag
     4621 cttgaacagt tcttttcaaa caggctgacc ccttacgcat tgacattgat ccgtcttttt
     4681 ccccatccag attttgtatt ggcatctact cggacaaaaa taaaaaataa actgatcaac
     4741 gaaacacgga aaaaaatctc cgcgaatcgt gccgagcaaa aggcagatca aatcatccac
     4801 tatgcacagt gtgcctatcc agctgttgaa aaagacagta tccactgtca aaaaacgatc
     4861 tattacgccg aacttctcca agatttactc gaacaaaaa
//
LOCUS       DAZUJR010000136         4893 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.140, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000136 DAZUJR010000000
VERSION     DAZUJR010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4893
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.140"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            506..1429
                     /locus_tag="ACG804_002750"
     CDS             506..1429
                     /locus_tag="ACG804_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RodZ domain-containing protein"
                     /protein_id="HFS4833616.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            1638..2216
                     /gene="pgsA"
                     /locus_tag="ACG804_002751"
     CDS             1638..2216
                     /gene="pgsA"
                     /locus_tag="ACG804_002751"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HFS4833617.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            2456..3697
                     /locus_tag="ACG804_002752"
     CDS             2456..3697
                     /locus_tag="ACG804_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HFS4833618.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            3806..4855
                     /gene="recA"
                     /locus_tag="ACG804_002753"
     CDS             3806..4855
                     /gene="recA"
                     /locus_tag="ACG804_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HFS4833619.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
BASE COUNT         1580 a          885 c         1115 g         1313 t
ORIGIN      
        1 gcttctcaaa tttttgtgat atttcggctt attgccgaag aagctacttc tggaacaccg
       61 tgtaccaaga ggttgtgaaa aagctgccct gcatcaagta ataagaacag ccaagtaaaa
      121 acagcttctt aatgttttta acttggttgg acttattacc gcagatgcaa gcttttgaac
      181 accgtttaag gaagaggttg tgaaatcagc gttttgacct gagtattaga gaaacatacg
      241 gaaaaatatc tccttatatt ttgccggttt ttgagctaat accgaggaac agctgattga
      301 acaccgttta agaaagaggt cgtgagcctg ccgtttaact ccgagtcaca aggaacaagt
      361 tcaaaaaaca gcttcttata tttattggat attgtgactt gtgaccgagg agttggcagg
      421 agaacaatgt ttattcggaa aaaaggagct gtgacatgac ttttgtcaca gcacccaaac
      481 ataacgtctt tcgttgcaac agcagatgct tcggagaatc aaacagactg gagaagatga
      541 acgagtggct tttgaaacca tcggagaaaa attacggcaa gcacgcctga ataaaaaaat
      601 atctttagat gaattacagc agattacaaa aattcaaaaa cgttatttgg aagcaatcga
      661 caatgatgat tttgaccaat tgcctggtaa attttacgtg cgggcattta ttcggcaata
      721 cgctgaagct gtaggagaag atggagacca tttagtcgat gtttttgatg ggaaaagcaa
      781 attgacagga tcggtccctg aacgtccgca gcctgaaaca gtaagtactt ctagaaaagc
      841 aatgcatcag gaagaatcgc atccaagtcg cttttggaca agtcttcctg tcattttatt
      901 aggattggtt gctttggcga ttgtcgttgt cgtgggctat atgacttggc aagatcgtca
      961 agctgatcca ataatcggag acacagcttc ttcgcttaaa gtagaaggat cagtcgagga
     1021 gtcctcttcc tcagagcaaa gcacgcagac caaagagtct tctacagtag aatcaacaac
     1081 aaaatcaagt gaagaaaaga aaatggcaat agctacagga gaagattctg gcagtgccat
     1141 cgcagtaaat atcacagacg ctaccaagcc tgtaaccctt gaatttactg ctgtcaatcg
     1201 tgtatggtta ggtgtgctag tagacaatgc ctatgtttat caagggacac tggcagcaaa
     1261 tgaaacacag agtaccgtgt taccggaaac agcaacaaat gcgaccatca cgattggtgc
     1321 agcaagcaat gcaacgatca aagcgaatgg agaatccgta ccagttaatc caggggaaaa
     1381 caatcagagt ccaaaaaatg tgaaccttac tcttcaatac gcagaatgat cgtataaatt
     1441 agtttacgca tctgtttact tgtaggtata aaaaagaagg atcgtgacaa atctgtgtcg
     1501 cggtccttct tcgttaattc aaaaagatca atttcaataa aaatactcct ttgaataaat
     1561 tcatttggaa aagtaaataa tatcggtgga aacttcgctg atagtcacgt agaataggga
     1621 agaaaggagt cgatagtgtg aatttaccaa ataaattaac tgtacttaga atttgtatga
     1681 tcccgatttt cattttggtt gtaggtttac ctttagattg gggacaattt aacgtaggag
     1741 acaccacact ggctgtcaca cagctagtag gtgcagttat ttttgcttta gctagtatca
     1801 cagactggtt agatggaaaa attgcccgtg cgcgaggcct tgtcactaat tttggcaagt
     1861 ttgcggaccc gttggcagat aaaatgctag ttatgactgc ttttatcatg ttggttgacc
     1921 aaggaaaggc ccctggttgg gtagtagcga tcattgtctg tcgtgaatta gccgtcacag
     1981 gcttgcgttt actacttgtc gaacatggag aagtcatggc tgcagcttgg ccgggaaaag
     2041 tcaagacggc tacacaaatg gttgctatta tcttgctgtt tatcaataat atcccattca
     2101 gcctgatcgg tattccagta gatcaaatca tgctttatgc ttgtctgatc tttactatct
     2161 attcaggtgt ggattacttc atcaaaaaca gcggtgtgtt caaaggatca atgtaagtat
     2221 cgtttagtgg agaggttgtg agcctgccgt ctaactctga gtcacaaggg ataatttcaa
     2281 aaaacagctt ttcatgtttt atgtatattg tgacttatga ccgaggtttt ggcaggagaa
     2341 cactgtttat ttggaacaag gagctgtgac aagatttttg tcacagctcc ttgccctctt
     2401 tttaaataaa aaaatataaa aatacagcgt atactatata agggagcggg aagtaatgaa
     2461 agcagaaata atagctgtcg gaacagaact tttactagga caagtcgtga atacgaatgc
     2521 cactttcttg tcagaacagc tagctgatct aggtatcgaa gtttattatc aaacagttgt
     2581 aggagataat cagcagcgtt tagaagagtt gattgctcta gctgaaacaa gaagtgaact
     2641 catactctta tgtggcggat taggaccgac agaagatgac ctgacaaaag aagcaactgc
     2701 ggctcacctc ggtaagtctc tcatacaaaa tacggaagga tacaaaaaat tattggcata
     2761 ttttgaaaca acccatcgaa aaatgaccaa aaacaatctg caacagtccc agattatcga
     2821 aggcggggtt cctctaccaa atcgtacagg gcttgcttta gggacttttt atcaaacaga
     2881 tacacatgcg tatatccttc ttcccggtcc gcctaatgag ttgaaaccaa tgtttgtgga
     2941 acaagtacgt cctttactag aggaacgttt tccttctgaa gaaaaactaa tttctaaagt
     3001 tttgcgcttt tatgggattg gtgaatcgcg actggtcact gagctaaaag atctgattga
     3061 gacacagatc aatccaacga tcgcaccata tgccaaacca aatgaagtga cattacgact
     3121 gacagtgaaa acaaatgatg ttcaggcagg gaatcaagct cttttagcat tagaagaaaa
     3181 aatccaagaa cgagtagggg aatattttta tggatacggc gatgataatt cgctagcaaa
     3241 agtcgtagtg gaactactga aagaaaacaa gcagactgta acagcagcgg aaagtttgac
     3301 agccggcgcc ttccaagccg cattaggcga cattgctggt gtatctgaag tatttccagg
     3361 cggattcgtt acctactcgc tccaaacaaa agctggtttt ctggagattg atccggagct
     3421 attagcagaa tatggaacag tcagcaaaga atgtgtggag cagatggcca ttcaagcacg
     3481 tgagatagca agaacagatt acagtgtagc tttcaccgga gtggctggac cggacacgtt
     3541 agaaggtcaa tctgcaggaa cagtatggat cgctatttca tctaaagacg gcgtggtttc
     3601 ggaaaaatat cactttgcca gagatcgtgc tgctatcaga tataatgcgg ttatgcaagg
     3661 atttgatctt ttgagaaaac agcttttaag aaaatgataa atgcgaatat ttgttcggtt
     3721 ttttcttgct ttttttcact aaaaaagata tgataaggat aatgaaatgt tgctctgatt
     3781 tgtaaatata aggaggatta tcgtattggc agatgatcgt aaagcagcct tagatgctgc
     3841 actgaaaaaa attgaaaaga gctatggtaa aggctctatt atgaaattgg gcgaaaaaat
     3901 cgaccaacaa atctctacaa ttccaagtgg ctctcttgcg ttagatgtcg ctttaggtgt
     3961 cggcggttac ccccgtggac gtatcatcga agtatatgga cctgaaagtt caggtaaaac
     4021 aacagttgca ctacacgcta ttgcagaagt acaaaaaaat ggcggaacgg ccgctttcat
     4081 tgatgctgag catgcgttag atccgcaata tgcacaaaaa ttaggtgtga atatcgatga
     4141 actacttctt tcacagcctg acacaggaga acaaggtcta gagatcgctg atgctttagt
     4201 atcaagtggg gctgtagata tcgtagtagt cgattcagtt gctgctttag ttccacgagc
     4261 agaaatcgac ggcgaaatgg gtgactcaca tgtcgggtta caagcacgtt tgatgtctca
     4321 agcattgcgt aaactctctg gttcgatcaa caaaacaaaa acaatcgcta ttttcatcaa
     4381 ccaaatccgt gaaaaagtag gcgtgatgtt tgggaatcca gaaatcactc ctggaggacg
     4441 cgcattgaaa ttctacgcaa cgatccgttt ggaagtacgt cgtgcagaac aattgaaaca
     4501 aggtacagat attgttggta accgtacaaa gatcaaagtc gtaaaaaaca aagtagcacc
     4561 tcctttcaaa atcgctgaag tagatgtcat gtatggttta gggatctcac aagaaggaga
     4621 acttctagac atggcagtag aaaaagacat tgttgataaa agcggtgctt ggtattctta
     4681 taaagaagat cggattggtc aaggacggga aaacgctaaa atctatatgg ctaatcatcc
     4741 tgaaatgatg gcagaagttt ctgctctagt tagagcagct tatggtattg gtgaagaagt
     4801 cgctgtccca gaagatgaaa aaggacaaga agaattgcct ttagtagaag aataaaaatt
     4861 atgataaaca aaaacggctg gtctgaagag tag
//
LOCUS       DAZUJR010000137         4845 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.141, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000137 DAZUJR010000000
VERSION     DAZUJR010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4845)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4845)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4845
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.141"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(71..1681)
                     /locus_tag="ACG804_002754"
     CDS             complement(71..1681)
                     /locus_tag="ACG804_002754"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HFS4833620.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            complement(1903..2148)
                     /locus_tag="ACG804_002755"
     CDS             complement(1903..2148)
                     /locus_tag="ACG804_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833621.1"
                     /translation="MKEKDCFYDKLYKLLLQVGKSSSLLGGILSIIMFVLFFYLLFHL
                     KFFSNDFLICLGLTLAMFISSLLCGLNFFCTHKGLKK"
     gene            complement(2874..4214)
                     /gene="glnA"
                     /locus_tag="ACG804_002756"
     CDS             complement(2874..4214)
                     /gene="glnA"
                     /locus_tag="ACG804_002756"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HFS4833622.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            complement(4242..4634)
                     /locus_tag="ACG804_002757"
     CDS             complement(4242..4634)
                     /locus_tag="ACG804_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFS4833623.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
BASE COUNT         1422 a         1044 c          796 g         1583 t
ORIGIN      
        1 agagaaaagt gacaagaaaa ttgcttatcc ccttctcttg ctacttttct ctttctatca
       61 agttcaaaaa ttattttgtt tcgtgatctg ctaatgatgc tccgacaaat gctttgatta
      121 atttttgcgg gcgatttgga cgagaaatca attctgggtg gaattggcat cccacaaaga
      181 attttttctc tggcagctct acgatttcta ctaaacggtt atctggtgag acacctgaaa
      241 agactagccc ttgttcttca aacaattgac gatatttgtt attgaactca tagcggtgac
      301 ggtgacgttc ttgcacaaca tcggctccat catatgcttc agccgtcttc gttccttttt
      361 tgattttaca tgggtataat ccaaggcgta aagttccacc caaattctcg atgttttcct
      421 gatcagccat taaatcaata atattgtttg ctgtatctgg attcgtttca gctgatgacg
      481 catcttctaa tccaacgacg ttacgtgcaa attcgacaca agccatctgc ataccaagac
      541 aaatacctaa aaacggaacg tcattttcgc gagcataacg aatcgcttcg attttccctt
      601 ctactccgcg atcaccaaat ccaccaggaa ccaagattcc atctgcgtct ttcaaacgtt
      661 cttctacatt ttctctcgtt aattcttgtg ctttgatcca atcgatctcg atgtctgaat
      721 tataggcgaa accagaatgt ttcaatgctt caactactga gatatatgca tctggtaact
      781 cgacatattt accgacaagc gcaatccgta cttttttctt caagttcaag acacgttctt
      841 ctaattcttt ccattctgtc atgtctgctt ctggtgtatc tagttttaaa tggtcgcaaa
      901 caatttgatc cattccttgt gcttgtaaaa ctaatgggat ggagtaaagt gtatctacat
      961 ctggcgactc gataactgct tctggttcga catcacaaaa ttgtgccaat ttgtttttca
     1021 cgctttgaga aacaggttgc tctgtacgta ccaccaaaat attcggttgg atacctaaac
     1081 cacgtagctc ttttacactg tgctgcgttg gtttagtttt catttctcca gcagctttca
     1141 agtaaggaat caatgttgta tggatataca taacattatc tgtaccgaca tctgctttca
     1201 tttgacgaag tgcttcaagg aatggcaaag attctatatc ccctactgtt ccccctactt
     1261 ctgtaatgat cacatctgaa tcagtcattt tagctgctcg catgattttt tctttgatct
     1321 catttgtaat atgaggaata acttgaacag ttgctcccaa gtattcgccc ttacgttctt
     1381 tacgcaaaac ttcagaatag atttttcctg tcgtcacgtt ggagtatttg ttcaaattga
     1441 tgtcaataaa acgttcgtag tggcccagat ccaaatctgt ttcagcacca tcatctgtta
     1501 cgaatacttc tccgtgctga tatgggctca tcgtccccgg atccacgttg atgtatggat
     1561 caaatttttg gatagttact tttaagccgc ggtttttcaa taagcgtcct aaagaagctg
     1621 caacaatccc ttttccgatt gatgaaacga caccgccggt cacaaaaata tattttgtca
     1681 taagttcaaa aactcctttt taatttatgt gcaggaaaag tctcagacaa taaacaaagc
     1741 tccctattct tcaataagaa tagggagccg aaatttctgt aaacttctga ccctctaaaa
     1801 gggtgcccaa ggtgtataat acaagctgac taagggaaag tcaagtactc aaatgaatac
     1861 tatccgctta caattttttc tttttcgata tcctttgaga aattatttct taagtccttt
     1921 atgagtgcaa aaaaaattta acccacataa taagcttgat ataaacatag ctaacgttaa
     1981 acctaagcaa atcagaaaat cgttactgaa aaattttaag tgaaataata gataaaaaaa
     2041 taaaacaaac attatgatag ataatatccc acctaacaaa gaactacttt ttcctacttg
     2101 cagcaacagt ttatatagct tatcgtagaa acaatctttt tctttcaccc ttatttacct
     2161 cctttacgta aaaaacgtag tccacagttc tcggattttt ggcatatctt ttctattaaa
     2221 taatatcaaa aacaaaacaa ttccactaat tttttcaaag atgacctttt tttcaacaaa
     2281 agtgccttgt agggattcat tgaaggtaac gaatcacata agtaaaaaat aaggagatgc
     2341 gacaaaagtc gtgcctcctt atttctaaat aaacggtgtt ctcctgccaa ctcctcggtc
     2401 acaagtcaca atatccatca aacatgagaa gctgtttttg aaattatttc ttgtgattcg
     2461 gagttaaatg gtaggctcac aacctctgga taaacggtat tcaaaagcca gtttctcggt
     2521 attaagccaa atttatgcaa aaatgtagaa agccattttc acaaaatttt tcttaatact
     2581 cgaaactaaa cgtctttttc aaaacctctt ggtaaacggt gttcaaaagc ttgcatctgc
     2641 ggtaataagt tcagccaatt caaaaacaag aaaagctgtt tttgcttggc tattcttatt
     2701 acttgttgca gggcagcttt ttcacaacct ctccactaaa cggtgttcaa tcagctgacc
     2761 ctcggtatta gctcaaaaaa cggcaaaata tgaggaacta tttttccgtt agtttctcta
     2821 atactcaggt caaaacgctg atttcacagc ctctaattca cggtattcct gttttaataa
     2881 agttctagat attgttctct ttcccactcg gaaacagttt gtctgaatgc cgcccattcg
     2941 agacgttttg cttcaacaaa atttgagaag atatgttgtc ctaatgcgtc aatcattaca
     3001 ttatccttac gcaattcttt gatagcatta tggatagttg aaggtaagtc ctggatatgt
     3061 gcagcttctc tttcttcctc atccattaca taaatgttac ggtcaacagc tgctggcggt
     3121 gtgatctgat tacggatacc gtctagtcct gcttgcaaca atactgccat tgccaagtat
     3181 gggtttgcag atggatcaac tgaccgcaat tccaaacgtg tggataaacc gcgagattct
     3241 ggtacacgta ctaatggcga acgattacgg ccactccatg cgacataaac aggcgcttca
     3301 taacctggaa cgagacgttt ataagaattg actgttggat tgcaaacggc tgtgtaggca
     3361 cgagcatgtt tcagcaaacc acctaagaaa tgataagctg tttcacttag ttccaattca
     3421 ccgtctttat catagaaaac atttccttca tcattgaaca aagacatatt gcaatgcata
     3481 ccagaaccat tgatcccaaa taacggtttc ggcatgaaag tcgcgtgaag tccatgcttg
     3541 cgtgcaatcg ttttgacaac gagcttgaag gtttggatat tatcacaagc atctaccaca
     3601 tctgcatatt taaagtcaat ttcatgctgt cctggcgcta cttcatgatg tgaagcttcc
     3661 acttcaaagc ctagactttc taattccaac acgatgtcac ggcggcaatt ttcacctaaa
     3721 tctgttggtg caaaatcaaa ataaccacct ttatcattca aggtcgttgt gatcccaccg
     3781 tcttcgtcta atttaaataa gaagaattct ggttcaggtc ctaaattgaa agaggtaaaa
     3841 ccaaggtcgc gcatatcttt caatgctcgt ttcaaattcc cgcgaggatc gccggcaaat
     3901 ggtgtcccat ccggattata gatatcacaa attaaacgag caacttttcc atgagcactt
     3961 tcccacggga agatcatcca agtggagaga tctggataca aatacatatc gctttcttca
     4021 attcgaacaa atccttcaat cgaagaaccg tcaaacatca ttttattttc taatactttg
     4081 tcgatctggc tcactggaac ttctacattt ttgatcgtac ctaagatgtc tgtgaacatc
     4141 aatcgtaaaa atcgtacgtt ttcttcctca atgattcgtt tgatttcttc acctgttatc
     4201 tgtttcttta ccatggtatc cctcttcctt ttttaattta ttcagtcaaa gaattgtctt
     4261 tgcaatcctt gcgactgata atgacctgtt ttgcttaacc caccttgcgc caaaatctca
     4321 tcacgaaaaa tttgtcgaac gtcatgatct gtcaacggct tcttgttttt tgcttcttgt
     4381 tttttcgcct gtgccatttc gtatacacgt ttgatcccag ccatattcaa tccctctgaa
     4441 agatagtctt taatctcaag caacatatca atatcattca gcgaatacat acgtcggttt
     4501 ccttcgcttc gttccggatg aactaaatct tgttcttcat aatagcgaat ttgccgagca
     4561 gacaaatcag tcagcttcat aactgtacca attggaaata cggacataga tcggcgcaat
     4621 tccttttctc ccatcagacg tcccctttcg ttttataagt tggctaaagt gtaccaatta
     4681 aaaaaaatat tgtcaactgc atatgttagg ttttctaaca tgagatctct attttttata
     4741 aaataacaaa aaaataagaa cacaaaaaag gtatctagtt gattttcgta ccagatacct
     4801 tttatttttt attatactgt actatccttt attagtgttt ttatt
//
LOCUS       DAZUJR010000138         4700 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.142, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000138 DAZUJR010000000
VERSION     DAZUJR010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4700
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.142"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            61..915
                     /locus_tag="ACG804_002758"
     CDS             61..915
                     /locus_tag="ACG804_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFS4833624.1"
                     /translation="MENSIYLVTEPNTQLKDCYFNFCGYSKTEPRHSFGPAIREQYLI
                     HIVLEGEGYYSINDQKYFLKKGQGFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYY
                     LKEIGVGKNHLTFKVENLNSFKGLIFETLSYDQDNLVSELSRQKQVYKFLELLLNSAS
                     YLNEGIITKKMNPFVRQTIEIIRENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISI
                     KEYISEIKISIANDLLSSTEYSIQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRL
                     GLGIINGE"
     gene            1012..3261
                     /locus_tag="ACG804_002759"
     CDS             1012..3261
                     /locus_tag="ACG804_002759"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HFS4833625.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3264..4439
                     /locus_tag="ACG804_002760"
     CDS             3264..4439
                     /locus_tag="ACG804_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4833626.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTRVTRGAS"
     gene            complement(4442..>4700)
                     /locus_tag="ACG804_002761"
     CDS             complement(4442..>4700)
                     /locus_tag="ACG804_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFS4833627.1"
                     /translation="GITISVPPRKNMDKSEKLDHSLLGKQRKTVETVFSSLEKLGCQN
                     FNSRSVKGLESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT         1639 a          678 c          854 g         1529 t
ORIGIN      
        1 atgtaataat ataaacataa taaaacaaaa attatccaaa tctaacatag gagggtggat
       61 atggaaaatt ctatatattt agtaacagaa cctaacactc agctgaaaga ttgttacttt
      121 aatttttgtg ggtattcaaa aacagaacct agacatagtt ttggaccagc tattcgagaa
      181 caatacttaa tacacatagt gctagaaggt gaaggctatt attcaattaa tgatcaaaaa
      241 tattttctga agaaaggcca aggatttgtt atcccaccag gagtatctac tttttatcaa
      301 gcagatgaaa aaaatccgtg gtcatatgta tggttgggtt taagtggcaa tcttgtagaa
      361 tactatctaa aagaaattgg tgttggaaag aatcatctta cctttaaagt cgaaaattta
      421 aattcattta aaggattaat ttttgaaact ttatcgtatg atcaggacaa tctagtcagt
      481 gaattgtcca gacaaaaaca agtttataaa tttttagaac tcctcttaaa ttcagctagt
      541 tatctgaacg aagggataat tactaaaaag atgaatcctt ttgttcgtca aacaattgaa
      601 ataatacgtg agaatgcgta tcaaaaatta tctgttaaag atattgctgt cagtctatcg
      661 atacacgaaa attatttatc acgattgttt aagaatgata tgggaatatc aataaaagag
      721 tatattagtg aaatcaaaat ttctattgca aacgatctgt tatcatcaac tgaatattca
      781 atccagcaaa tcagtgacaa gataggattc tcaacagtac aatctttttc taaagccttt
      841 aagaaagcaa atggtgtttc accgggagta tatcgaaaac gtagattagg tctaggaatc
      901 attaatggtg aataaactaa acatttgatt ttgataaata ttcgttactt taaacgctta
      961 ctatttatgt gagcgttttt tataatgcaa taaagaaacg gaggagagct tatgtataag
     1021 gataatgaaa tgaatattat ttatcgatca gaaaaccaac aatttcattt gtttaatcag
     1081 gagataagtt acatttttaa gatatcggaa gatggtaaat tattgcattt atattatggt
     1141 gagaacttac cagataatga ctatagtcat ctaattgaga tgcatcatcg gcctatgaca
     1201 acctatagaa atgaaaacga tttgctatat tcgttagagc acttaaaaca agaatttcct
     1261 gaatatggta caacagattt tagacatcct gctatttcat tactacagaa aaatggctct
     1321 cgcttatcag attttgtcta tcaagggtac gaagtggaag aaggaaaacc taaactagaa
     1381 ggtttacctg ctacctatgt tgataataat gatgaaagca aaacattgaa agtttatatt
     1441 ttagattcag ttacaaatgt tcaagtagaa ttattatata caatttatag agattatcct
     1501 gttattactc gtagcgcgcg agttatgaat aaaggaaaag atattcaaat aatcgagaat
     1561 attagcagtt tatcattgga tttacccgat gcaaattatg aatggcaaca attatctggt
     1621 gcttggggta gagaaagaac tattaagtcg cgtactttac aacaaggaat tcaatcaatc
     1681 gaatctactc gaggtatttc aagccatcag cataacccat ttgttacttt aaaaagaaaa
     1741 aatactgatg aaaatcaagg agaagctatt ggtgcagcac tagtttactc aggaaacttc
     1801 ttaattcaag cagaagtaga tacatgggat gttactagac tacaagttgg catcaatcca
     1861 tttggattta attggaaact caatccagga gaaatattta cagcaccaga agcgattctg
     1921 gtttattcaa gtaagggttt aaatgccatg agtcaaactt ttcatcaact atttagaaaa
     1981 cgcttagctc gtggtaagtg gcgagaaaaa gaccgtcctg tcttaattaa taattgggaa
     2041 gcaacatatt ttgattttga cgaagaaaag ttggtaaata ttgctaaaaa agcatttgat
     2101 gttggtattg aattatttgt attagatgat ggctggtttg gagaaagaga aaacgattgt
     2161 gcaggattag gagattggca tgtaaatcct aaaagactac ctagaggaat cggcagcctt
     2221 tcagaaaaaa ttcgtagttt tggtatgaaa tttggtttat ggtttgaacc tgaaatggtg
     2281 aataaggata gtgagttata tcgcacacat ccgaattgga ttatttctac acctaatcga
     2341 aaacctaatc atggtaggaa ccaatatgta ttaaattttg ggttagatga ggttgttgaa
     2401 aatattttcg atcaaatgtg taaaatcatt gatgaatcaa acttagatta cattaagtgg
     2461 gatatgaatc gtccattgac tgatgtattt gacagtcact tgtcagcaga tcaacaagga
     2521 gaagtattcc acagatatgt actaggcgta tatcgcttat atgaaaaact tataacaaaa
     2581 tatcctaaca tactatttga gtcttgttca tcaggtggtg ggcgctttga tcctggaatg
     2641 cttcactatg cacctcaagc ttgggctagt gatgattcag atgcaattga aaggttaaaa
     2701 attcaatatg gaactagtat gctgtatcct ctttcgtcta ttggtgctca tgtatcaatt
     2761 gttccaaatc atcaaacaaa ccgtataaca cctataaaaa ctagaggaaa tgtagctttt
     2821 tttggtgcat ttggatatga gcttgactta aatgaattaa gtgaaggcga tttgaggatt
     2881 gtaaaagaac aaattgcctt ttataaaaaa tatagaacca taattcataa tggtactttt
     2941 tatagactat tatcaccatt cgatgatgat aatcaaaccg cgtggatggt tgttagtcat
     3001 gataagaaaa cggctattgt tgctcattat aaaacattaa atgaggtaaa tgctccttac
     3061 cgccgactga aattaaaagg gttagataat gacggacttt ataatgtagg acaaaatagt
     3121 ttgcgatctg gaatggaatt gatgagagca ggactagtct gttcagatgc atctagtgga
     3181 caaataaatg atcagaatcg acgcccagaa acatttgatt ttgattccaa gatttgggtt
     3241 ataacacagg aggaaaagta gagatgaata accaaaaaag cttacttcaa aaaggagcaa
     3301 tcttaagtat ttcactaatg ttaacaagct ctcaagcaat taatggtgtt attccacaaa
     3361 tgaaacagtc tttggggata tcacaaagtc aaagtgaact tttaggaact gcaccaagta
     3421 taactgttat tttgtttatc ttattatcta gttactttgc caaaagaata ggaatgaaaa
     3481 agacaataat tttaggttta ttattagctg gtataggagg aattattcca gtatttacag
     3541 ctaccttcca aaccgttctt attagtcgag taatattagg tgccggttta ggagtatata
     3601 attcattggc tgtgacatat atcagctctt tatactctgg caatactaga gcaacgctat
     3661 taggtattag aaattcaatg gaagctttag gtcagacaat ccttattttt cttgctggag
     3721 ttttagtgaa cattaattgg acggcttcgt ttttagtcta tgcaattgcg tttcctgtag
     3781 ctctcttatt cgcgctaaaa gttcctgaaa ttagagatga aaatagtgac atacctgaaa
     3841 atcatgtaaa agaaaagatg aatccaatgg tttttgccct agttctattt gcaatcttac
     3901 tcgtaatgaa tagtattgct atttctgtac gatttgcatc aattgcaact gaaattaaag
     3961 gggtaaactt taatgctagt aactatttag ctctaatgcc tatcttagga atactagcag
     4021 gatttatgtt tggaccaata aataagtgga taggaaaagg aaccctatac ttgggaatta
     4081 tattctttat aatttcaaat ttgttaattg ctgtgtcaaa cggtaatatg acgttcctgc
     4141 taacgggttt atttttatca agtataacag gatcatggtg cttcccattt atctttagta
     4201 acttagataa agtcactaca aagaatacaa ttaattttgc tacttcattg atttttattg
     4261 gctgtaatat tggtaatttt atagctccta ttgctatgca attagcacaa tttctaacaa
     4321 gaagtacaaa tttgactgct ccattttttg tattcgcagg aatatttatt gtgatcctat
     4381 ttgtaacatt ttttgcgaca aataaaaaaa atactagagt aacccgtggt gctagttaat
     4441 tttaatatcc taaagaatat ctcaaagttc cttcaaaacg tcgttgtgct cgacttaata
     4501 gaacactgta agccagtaat atgctttcaa atctactctc tagcccttta acagaacgtg
     4561 agttgaaatt ttgacaacct aatttttcta aggaagaaaa aacagtctca actgtttttc
     4621 tttgttttcc aagtaagctg tggtctagtt tttctgattt atccatgttt ttacgtggcg
     4681 gaacggatat agtaatgccc
//
LOCUS       DAZUJR010000139         4586 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.144, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000139 DAZUJR010000000
VERSION     DAZUJR010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4586
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.144"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            186..2855
                     /locus_tag="ACG804_002762"
     CDS             186..2855
                     /locus_tag="ACG804_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HFS4833628.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEVSFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEKPRNTHRRRRRK"
     gene            complement(2946..3560)
                     /locus_tag="ACG804_002763"
     CDS             complement(2946..3560)
                     /locus_tag="ACG804_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFS4833629.1"
                     /translation="MINATDEILSVNKVFYTVPAEKMSRVSSDINTITSRIGLTKAMH
                     MVLKYNQEDPPVPKTYEAIDLIIVDEIDRLKLQHLEQLRDIYDRNDLAMVLIGMPGIE
                     KRLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWADLGIDIKLEDFSDYEAITTIIK
                     ITKGNFRLIHRLFAQIDRILRINQMDKITVEVVEAARDSLVIGI"
     gene            3679..4218
                     /locus_tag="ACG804_002764"
     CDS             3679..4218
                     /locus_tag="ACG804_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833630.1"
                     /translation="MKKLFSALFILLFGFIGIGTSGNIVKASTMVEQTSEMAKTFSQL
                     TPEEQSYFKSKGFSDKDTFYTQKIEPQDPKTRFSANVLRLTASTKKITNTQGRTEYII
                     TSPNSAMYRISTRLSLGSAKSYTQTVNLANSYGYGGGMYFTFTGKRQYYSVKLAMQVY
                     NTFGVGSVSCTAGGLTIGK"
     gene            4215..4553
                     /locus_tag="ACG804_002765"
     CDS             4215..4553
                     /locus_tag="ACG804_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0046685 - response to arsenic-containing
                     substance [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic metallochaperone ArsD family protein"
                     /protein_id="HFS4833631.1"
                     /translation="MIISYYVLNRSDDEGLFVFQSLHEDTMLKEFYNRIKNKQIETNL
                     YFLSDSILPFISNPKILNLLQTKDLKSLPIIVIDEEIVKYGAYLSVEELEKLTNIGMS
                     IQEDNGVHGT"
BASE COUNT         1418 a          790 c          860 g         1518 t
ORIGIN      
        1 atttttaagg gtgggacttt tgattcctac cctttttttg cgtttatttt tgttatacga
       61 acaaattatg aagttattta ttctaaattt tatttttttg tgaaaattag actcttttta
      121 agcagagaaa aacaaggata tgataaactg aatacaactt catagaaatt tggtggaaaa
      181 taaatatgaa aaaaaattta aagtcattct ttagagaaaa cggacgctac gcagcagcta
      241 gtttcctgat tccgtttttg attttagcac ttgtttatct aagtatcggg atctatcctg
      301 gaagcagcag aagtattttg gcaagtgatg ccttttcaca gttttctaat tttcatgcca
      361 gcttccgaaa tgttcttctt ggaaagcaaa gtatttttta tacatggaat gcttctctag
      421 gattgaatta tttatcttta atttcttact atctaggcgg gatcttcacg ccactggtgt
      481 tcttttttcc aaaccagatg atgccagatg cactgtatgt tctgactttg cttaaggtcg
      541 gctgtgccgg attggctttt tggtttcttg cacgtacgtt caagattcct cgctgggggc
      601 atgttgcact tagcgtcagt tacgcattga tctcatttat cactgcacat tcggagatca
      661 tcatgtggct ggatgcattt gtttatcttc cattagtgat tttggggatt catcgtgtta
      721 tggatcttaa acggccgaaa cttttattta tcagttattt actcttgttt ttatccagtt
      781 tttatatggg ttttatgatt ggcgtatttt ctttcttata ttttatcgcc cgtctattga
      841 caaactggtc agaatataaa aaaacgattg ttccttatgg tatcacttct ttactggcag
      901 gcggcgcttc aatgatcatt gtattgccag cagtgctgga tcttcggtca aatggcgagg
      961 cactgagtca gatcactacg ttgaaaacag aagcgacttc ttatctggat ctaatcatga
     1021 aaaatatgat tggtgtttat gacacgacaa aatacggatc gattccgttc gtttacgcag
     1081 gtctgctacc attagtcctc tgtctgtttt attttgccag tcggaaagta ccgttgaaaa
     1141 ataaattttt gtacggcagt cttttcgcca tacttatcgc aagtttctat cttgttccat
     1201 tgaatttgtt ctggcatggt atgcatgcac cgaatatgtt tttattccgt tatgcctatc
     1261 tgttctcttt cttagtgctc ctgcttgcag gaaaaggatg ggaaaagata gaacaagacg
     1321 atcgtgggct gttgttagga atcattttgg tcgtagctgc tctctttgcg gtggcatggg
     1381 gcatcaaacc tgaaggaagc tacacctatg tgacgatgac ttcctttgta ttgacagtgg
     1441 ttttcttagg gatttatgct tttgctgtgg gattttatca gcataaaaaa ctttcattca
     1501 atcatctgag tatattgtta ttattgatca tgtctgctga agcactggtc aatacgaaca
     1561 gtatgatcca tggcattctt gatgattgga attatgcttc ccgcagttta tatactgatc
     1621 cttatcctga cttgaaagct cttgtaaatg aaacaaaaaa agattccgac tcgttttacc
     1681 gcttggaaaa tctggatcca gtatctgcaa acgattcgat caactatggt tacagtggta
     1741 tcagtttgtt ttcttctata agaaatcgta attcttcctc ttacctggat aaattaggtt
     1801 tccgttcaag agggacaaat ttgaatatcc gttataacaa taatactttg ctaatggatg
     1861 ggtttacagg aatcaaatat aacatttcta aaaacgaaag cacgttcagt aaatatggct
     1921 tccgccaagc tggtcaaagt ggcgactata cactgtatca gaatgtcaat gcattgccac
     1981 tagcatttac tgcaccgttg tccgttaatg atgttgagca gccagtgaca gataatttga
     2041 ccagtcagac aaacttgatc aatacattgt ctggtttaaa tgaacagtat tttacattct
     2101 atacacctac tttgaagaat cagttgaata cgacgatcac aaagacaacg actggcgtca
     2161 cttactcaga aacagcagat aaccagccaa aagagctcac ttgggaagtc catgtgcctg
     2221 caaatacaca agcttactta agtttgttcc caaccaattt tgcacaatta gaaagttcta
     2281 gtgcgacgat cactgtcaat ggtacatcgc gaaaaacgca aatcaacatt tctggtcaat
     2341 actatgatct tggctattat cctcaagaga caacagtgac atttactgca agtttttatg
     2401 gaacgaaaga agtaagtttc atggagccta aagtcgttgg tctagatgtt gtagcctatc
     2461 aagccgcaat gaatcagatc aaagaaaaag gtgtcgaaat ggaagccact ggcagaaaag
     2521 cttctgggac tgtaaatacc gctgaagatt ccatgttggt gacaactatt ccttatgaca
     2581 aaggatggaa agctaaaatt gatgggaaac cagtcaaggt cagcaatttc aaagacgcat
     2641 tcttgatgat aaaagttcca gcaggtaaac atactgtcac tttcagttac ttgcctgaag
     2701 gatttacgat aggtgcaatc ctttttgtcc tatgtattgc attgtttatt ctttatgtct
     2761 ggtaccttga ccgcaatcgc cccttttatg gcacgattga tccagcaata gaagaaaaac
     2821 cgcgaaatac acacagaaga agacgaagaa aataaagaaa cgatggaatc tgtgtcactc
     2881 ttctatttaa atggcaaaaa tttcaatctt taaatgacaa aaaccacctg atttttggtg
     2941 gttttttata tacctatgac taaactatct cttgctgctt cgacaacttc tacagtgatc
     3001 ttatccattt gattgattct taaaatccga tcaatctgcg caaataaacg atgaataagc
     3061 ctaaaatttc cttttgtgat cttaatgata gttgtgatag cctcataatc agaaaaatct
     3121 tctagcttga tatcaattcc taaatctgcc catttgtatt ccaaaatatg atgtgtttcg
     3181 tccttactaa ggttatcaaa ttcatgtgca aatcctatgc gagagtaaag ctgcggataa
     3241 cgagacaatc ttttttcaat accaggcata ccgataagaa ccattgccag atcatttcta
     3301 tcgtaaatat ctcttagctg ttctaaatgc tgaagcttta aacgatcaat ttcatcgaca
     3361 ataattaagt caattgcttc ataggtttta ggcacaggag gatcttcttg attgtatttt
     3421 agtaccatat gcattgcttt agtcagacct attctactag ttattgtgtt aatatccgaa
     3481 ctgacacgag acatcttttc agctggtaca gtataaaaaa ctttatttac acttaatatt
     3541 tcatctgttg catttatcaa gaacaagaaa aagtctgaat attcaaaaaa ataacggtgt
     3601 acatttttaa aaggagatgt ataatcgaga tttagaaagc gttttcctca aaatttaatg
     3661 aattaggaag tgattactat gaaaaaatta tttagcgcac tttttattct gttatttggc
     3721 tttattggta ttgggacttc tggaaatata gttaaagcta gcacgatggt tgaacaaaca
     3781 agtgaaatgg caaaaacttt tagtcaatta acaccagaag aacaaagtta cttcaaatcc
     3841 aaaggattta gtgataaaga tactttttac actcaaaaga tagagcctca agatccgaaa
     3901 acacgttttt ctgcaaatgt attgcggtta accgcatcta ctaaaaaaat tactaatacg
     3961 caggggcgga cagaatatat tataacaagt cccaattcgg cgatgtatcg tatttctaca
     4021 cgcttgagtt taggtagtgc aaaatcatat actcaaacag taaatctagc taattcttat
     4081 ggttatggtg gaggaatgta ttttacattt actgggaaaa gacaatatta cagtgtaaaa
     4141 ttagctatgc aagtttataa tacatttggt gtagggtcag tctcttgcac tgcgggagga
     4201 ttgacaatag gaaaatgata atttcttact atgtcttaaa tagaagtgat gatgaaggac
     4261 tcttcgtttt tcaatcatta catgaggata cgatgctaaa agagttttat aatcggatta
     4321 agaataaaca gatagaaaca aatttatatt ttttaagtga ctctatcttg ccttttatta
     4381 gcaaccctaa aattcttaac ttgttgcaga caaaagattt gaaaagttta ccgattattg
     4441 tcattgatga ggaaattgta aaatatggcg cttatctaag cgtagaagaa ttagaaaaat
     4501 taactaacat tggaatgagt attcaggagg ataatggggt acatggaaca tagaatgaat
     4561 atgcacagtt gagaacggaa tttgac
//
LOCUS       DAZUJR010000140         4564 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.145, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000140 DAZUJR010000000
VERSION     DAZUJR010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4564
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.145"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..300)
                     /locus_tag="ACG804_002766"
     CDS             complement(<1..300)
                     /locus_tag="ACG804_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6056 family protein"
                     /protein_id="HFS4833632.1"
                     /translation="MNKHNRKITNNKELILLLIGIWGIFLLFNMYMPTMRADDVVYAS
                     RLDELGYLGASIEHYKTWSSRIIIELFLMFFSKHFMLWKLLNSTIMLGIVVLLCKY"
     gene            393..742
                     /locus_tag="ACG804_002767"
                     /pseudo
     CDS             393..742
                     /locus_tag="ACG804_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741963.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(1014..1304)
                     /locus_tag="ACG804_002768"
     CDS             complement(1014..1304)
                     /locus_tag="ACG804_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833633.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            1706..1942
                     /locus_tag="ACG804_002769"
     CDS             1706..1942
                     /locus_tag="ACG804_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833634.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            1949..3901
                     /locus_tag="ACG804_002770"
     CDS             1949..3901
                     /locus_tag="ACG804_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HFS4833635.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3973..4470)
                     /gene="dfrG"
                     /locus_tag="ACG804_002771"
     CDS             complement(3973..4470)
                     /gene="dfrG"
                     /locus_tag="ACG804_002771"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HFS4833636.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
BASE COUNT         1561 a          803 c          755 g         1445 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcagcag tatagattta agtagttcag ttttggagta caaaaagtga
     1501 aaatgtaaac ctaaatgagt atcaaattgc aactgaattt gatactcgtt ttttattgtt
     1561 aaatcaacgt ttgttgttaa tttacaccac aaaatgtaag ttaaaatgta tataaaaatg
     1621 cgaacgtgaa ataattattg taggaatgca aattggtgtg ttaaaatggt tacaatttac
     1681 taagcaaaaa ggggtgcatt ttcctatgca atttcttgag ccaaaaaata agaacgctaa
     1741 gtctgtggat tgggaaatat cagagcaagt aagggtgata gttaagcaat acgctgaata
     1801 tgcagagcgt actgaaagcg aagcagtgga tgaattctta ttgaacattt tagacgataa
     1861 gaagtttatt gaatggattg ccaacaagcg aagtaataag cggattgttg aaaaaatggg
     1921 tatcaaagat agagtgggtt gatagacaat gaccaagctt aaaagattag ccacgaagga
     1981 agatgaaatt gtagatgtta aaattccgat ttcaaacgaa gaattaaaag atagggctaa
     2041 acaatatgat ttattaactc caaaacgatt tgcaacaagg tataacaaaa tgttgttctt
     2101 gccaacgtct tttaaatgga acggttctga atatcccatt caatataatt actgcatcaa
     2161 tccgttttgt tgtaattttg ggaaagaaca gcacaaattc aaagatgtaa aagggaaacc
     2221 aagtcgatat aaaatgactg gtagttccaa agataaaggt cataaaggta tgtactgcaa
     2281 tgacaatcct attggcagag gtgtatcgca aaactgtaca gtaacccctt tatctaattg
     2341 gtctgttgtt gaagaaatta aacgccttat agaaatcaat agcatccaag atgttgagcc
     2401 agattatcaa tttcataaag aaggctgctc ggaagaagaa tcaaccccat tcaatgagcc
     2461 gaagcaattt tacaaaaggg ggaaaagtag gggcaaatct caacgctatc aatgtaaggc
     2521 gtgtaagaag ttcactaatg ttctaccaaa aagagaagaa accactactt atcaccaaca
     2581 aaagaacacc attcttccaa tgttcgctaa gatggttgtt ggaagggttt cagtcagtcg
     2641 tacttgtgat attttaggaa ttggagttgg aacctactat cataagctgg agtggctgta
     2701 taggcgttgt ttggagtttt tagaacgata tgagacacaa ccccttcaaa caaagaaatt
     2761 taacgagatg tggcttaata cggacaagat gcactactac ctaaataacg tccgtaagaa
     2821 aggacaaggt tcaaagaaat atacggggtt tgaagacctt aatatgcaaa cgtatatagt
     2881 tgtatctgct gaggtcttat caagatatgt gttccgttct gatgttgcct atgattggaa
     2941 tatttcaatg gatgaattaa atgaagatac aagaaaattc aaagaagacc atctcaatac
     3001 ttttagtcgt aaaaatgata ggttagattg gtcttattat ccacaagaac catccgctaa
     3061 cgatagcgaa aataggaatg cttatcttca cgaattaggg aaaattacta ataggagtag
     3121 atttgtcgat ggtttaaatg ttgatgctcc ttatactaca actgctcact attggttaat
     3181 taaacaaatg gttaatgccg acgaatggcg aatgattagt gatgatgact tctctattag
     3241 aaacgccttt tatagagtat tcacgaaaga attaaggttg agcgatgcac atcattttat
     3301 ttgccaagtt aacaagacga aaagcagaaa acaatgctta aaagaattcg gacaagcaaa
     3361 agcagaactg ctcgattggg gagatatcag aggattcaaa acaaagtttc tacggacttt
     3421 ggcatctcat tatctaactg aattactaac aagtcatcaa ttccacgaag aggctattag
     3481 taaagatgga gaaagatatc gcaaatatgc cgataaccct atcaaacatc cattagccac
     3541 taaggataaa ggattttatt cagttgattg tagaacggat ttatctgctc tggaaccaaa
     3601 cgaaatcgca aagatgctat taaatgttaa tgaccattcg accaatagct ttattcaaca
     3661 gataagacgt tatatatcat ctcttgaaag accattaaca acagctcgtg gtgataagaa
     3721 gagctatatt tacgctaact tcaatccgaa gtatgctcaa tttgcgatta caattctaag
     3781 aacttactac aacttttgtc gcccttttaa atcagcggat aaaaaggttt tgacacctgc
     3841 tcaaagatta gggattacag ataaacaatt tgattggaaa gatataattt atttcaaatg
     3901 acaaaaagag cttggagtaa tcccaagctc ttgtgcttta tctttactgt tcttcttcaa
     3961 ttaacgcacc cgttaactca ataagttttt tctttcatat acatgaaaat agtagttata
     4021 cggattttta tcattcttta tccctttttg ggcaaatacc tcattccatt cctcataatt
     4081 cacttctgga aaaaaagtat ctccttcgaa ttcatgatgt atttttgtga tgtacatttt
     4141 ctcaacataa gggaaaaaca aattataaat ctgttctcct ccgaaaataa aaatttcttc
     4201 ttcgttttta cataactcaa aaacatcttc tattgaatga acaatttcac aaccattaaa
     4261 ggtaaacccc ttatctctcg tcagaataat atttcttctg tcaggtaagg ctcttccgat
     4321 tgattcaagg ttcttcctac ctaatattat cggatgtccc tttgtagtat ttttaacata
     4381 ttcccagtcc ttgggaatcc tccaaggaat gtcattctct ttgccaatca ctctattctt
     4441 atccatcgca gcaatcaaag aaactttcat ttataacaca gcctttttaa ctaatttacc
     4501 atctaatttc ttatttctat caaaaaacct tttctcatta tcctgcccgt tagttgaata
     4561 agca
//
LOCUS       DAZUJR010000141         4486 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.146, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000141 DAZUJR010000000
VERSION     DAZUJR010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4486
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.146"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(28..963)
                     /gene="murB"
                     /locus_tag="ACG804_002772"
     CDS             complement(28..963)
                     /gene="murB"
                     /locus_tag="ACG804_002772"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HFS4833637.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(1036..1956)
                     /locus_tag="ACG804_002773"
     CDS             complement(1036..1956)
                     /locus_tag="ACG804_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFS4833638.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            2069..2821
                     /locus_tag="ACG804_002774"
     CDS             2069..2821
                     /locus_tag="ACG804_002774"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HFS4833639.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            3685..4218
                     /locus_tag="ACG804_002775"
     CDS             3685..4218
                     /locus_tag="ACG804_002775"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HFS4833640.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
BASE COUNT         1323 a          878 c          795 g         1490 t
ORIGIN      
        1 tttacttatt ttaagttcca ttacttatta attggctaaa cttctgcttg tttctgatat
       61 tgcttgtttt tctccaatga tccgcacttc tgtttctaaa gacacatcaa atttttcttt
      121 gattacttct tggatgtgcg caatcaattc aatataatct gtcgctgtcg catgatcgat
      181 attgacgatg aatccagcat gtttttcaga gacttgtgca ccgccccatt tcaggccttg
      241 caatcctgct tgttggatca gctgacctgt atagtgtcct actgggcgct taaagacact
      301 tccgcatgaa gggtattcta atggctgttt tgattgacgc aattcggtca actcatccat
      361 tcttgctttg attgcttcat aatcccctgt ttgcaaactg aatcgagctt ccaatacgat
      421 agcacgtaat tcttggactt tactgtgacg ataagaaaat accatttcgt cttttgtcaa
      481 agttttcaat gttccatctt caagcaaaag atccacttca gcaaaaacat ctttgatctc
      541 tccgccatac gcacctgcat tcatataaac cgctccaccg acacttcccg ggatgccgca
      601 agcaaattca aatccagtca atgattctgc caaagctgca taagtcgtat caatcagtga
      661 ggcacctgct tccgcaatga ccatcgttcc tttgacatga atctgtttca tttcagtcag
      721 catgatgact acaccgcgaa tcccgccatc ttgaacgatc agattgcttg catttcctaa
      781 taccatccaa ggtatatcat ggattcggca ataatcgatg atttgcttta cttcttcttg
      841 ttttttcggg aatgcaagga catcagctgg tccacctgtt ttcgtaaacg tatagttcat
      901 caatggttca tcaaacaata tagtaatcgt ggctaagctt tcaactattt cttctttatt
      961 cactgaggat tttcctttct tttctcaaac gtcctcatta ttctatcacg cttaatacaa
     1021 tcttgccagt cttgttcaaa gttgatgacg gtagtgatct ttaagcactt cctcacataa
     1081 ttcatgactt cttacaactt ctttttgttt aagcaattct gtttccgatt tacctaaacg
     1141 gatctgagaa aagaaggcct ctaccattgg ctcaaacccg cgtttgacta gcgtgtttgt
     1201 ccagtcgcca aattctttca ctttttttcc atcagcatct tgaatgacaa gctgggtcag
     1261 atcgtttact tcataagtac catttttact tgttacttga tatttttcta tattagcgcc
     1321 acttgctaaa tccatcgtta aaatagccgt ttgattttgt gtttctaatt gtaaaatggc
     1381 atattccaaa aattcctttg tttctcttat ctggtatttt gttctcaaaa tgggttcatc
     1441 taataaatac acagctgtat caataagatg taaaaacaaa tcataaagga cgaactctgt
     1501 cgtttctttt gccgctattc gatttttttg caggtggatc aaccgcttat ctgggatacg
     1561 tttcaattct tctaccatag gagcaaagcg ccggttgaaa ccgatcatca aaattatttg
     1621 gttcttatca gctaattctt gcaattcacg aacttcattt agatggacac tcagtggttt
     1681 gtcaatataa acatggatac cattttctag acattttttg gctaattcat aatgtacttt
     1741 tgttgctgcg tggatcatac atgcttcgat tttttcttct aaaagctcat cgatcgtttc
     1801 atatagatgt tggaacccgt actctttttg aattctttct tttgtttctt tatttcttgt
     1861 tgcaaaataa aaatcaagtg ttccttgttt tttcgcataa gttggtaaat atgctttttc
     1921 tgcgatattc cctacaccga ttacaccaat cttcatctac tttcctcctg gatcatttag
     1981 ttactttcat cttacaccat tttttactaa aatgaggtac aatagtatcg caaaggtaag
     2041 gaaattaatt cgaaggagtg tgcttttatt gaaatttatc tcttggaacg taaacgggct
     2101 tcgtgccatc gtaaataaaa attttttaga agtttttcat gagttagacg ccgatttttt
     2161 ctgtctgcag gaaacgaaac tccaagcagg acaaattgat ttagatcttc caggttatta
     2221 tcaatattgg aattacgcgg aacgaaaagg ctattccggc acagcgattt ttgctaaaaa
     2281 accagcattg aatgccactt acggaatggg tatcgatatc catgatacag aaggccgtct
     2341 gattactttg gaatattccg atttctttct tgtaacctgt tacacgccaa attctcaaag
     2401 cgaattaaaa cgtttagatt accgattaga atgggaagaa gccttttata attatttgga
     2461 aaatctaaaa aaacaaaaac cagtcatcgt gtgtggggat ctaaatgtcg ctcatcaaaa
     2521 gattgatttg aaaaactgga aaacgaatca aaaaaatgct ggattcactc cagaagaaag
     2581 agcggctctt tctcgactgt tggataacgg gtttatcgat acattccgtt atttttatcc
     2641 aacccaggaa ggtgtctact cttggtggaa ctaccgattc aattcaagga aaaacaatgc
     2701 tggttggcgg atcgattact ttttgacgag caaagattta gagccaggac tagctgatgc
     2761 aaagatccat acggacatta tgggcagtga tcattgtcca gtagaattag atttgaaata
     2821 aagaggttgt gaaaaagtcg tttagtttcg agtattaaga aaaattttgt gaaaatggct
     2881 ttccacattt tgcataaatt tggcataata ccgagaaact ggcttttgaa cactgtttat
     2941 cgagagattg tgaaaaagct gtcctgcatc aagtaataag aacagccaaa caaaaatagt
     3001 tcctcatatt tttcgtttgg ttgggcttat taccgcagat acaagctttt gaacaccgtt
     3061 tattaagagg ttgtgaaaaa gctgcactgc atcaagtaat aagaacagcc aaacaaaaat
     3121 agttcctcat atttttcgtt tggttgggct tattaccgca gatgcaagct tttgaacacc
     3181 gtttattaag aggttgtgaa aaagctgcac tgcatcaagt aataagaaca gccaaacaaa
     3241 aatagttcct catatttttc gtttggttgg acttattacc gcagatgcaa gcttttgaac
     3301 accgtttatt gagaagttgt gaaatcagcg tcctgacctg agtattagag aaacaaatgg
     3361 caaaatagtt cctcatattt tgctattttt tgagctaata ccgagggtca gctgattgaa
     3421 caccgtttag tggagaagtt gtgaaaaagt cgcctacttt cgagtcgtaa gaaatttttt
     3481 tgaaaatggt tcctcacaac tttgcataaa tttgacttaa taccgagaag tcatgatccc
     3541 catctaactc caaatcacaa ggaatgagtt caaaaactag cttttctcaa caaatattac
     3601 ataaaaaatt ctatgttttt tgttaaattt atttgctttt ttcaaaagta tgttacagta
     3661 atttcccaag gaggttttac agaaatgaat tttgttgcca tggattttga aactgccaat
     3721 catcagcctt atagtgcttg ttctcttgcg ctagtcatgg taaaaaatag ccagatcgtt
     3781 gatgaattct atacattgat acagcctgag actccttttt tctggcgaaa tgtccaaatt
     3841 cacggaatcc atcaagaaga cgtacgcaat gcgccgaaat tcccagaagt ctggcaaact
     3901 atccaaccat attttcaaaa aaatcgttta gtcgttgcac ataatgctgc ttttgataca
     3961 aaggtcttag cgggatgctt agattattat catcttgaac agcctaatta tctttcttta
     4021 tgtacagtga aaagtagccg tcgcctgttt cctgaatttc caaatcatcg attgaacact
     4081 gtgtgcgaaa atttgaacat ccaattagat catcaccatg atgcattgga agatagtcgt
     4141 gcatgtgcgg aaatcctgct ttatcaagaa aaaaaattcg ggacagatcc attgaaaaaa
     4201 cttgtgacta taaagtaaaa gaatacttat gaaacacaca aagaggtcgt gagcctgccg
     4261 tttcactccg agtcacaagg agcaatttca aaaaatagct tctcatgttt attaaatatt
     4321 gtgactggtg accgaggagc tggcaggaga acaccgttta ttggagaggt tgtgaaaaag
     4381 ctgttctgca tcaagtaata agaacagcca aacaaaaata gcttctcata tttttcattt
     4441 ggttggactt attaccgcag atgcaagctt ttggacaccg tttacc
//
LOCUS       DAZUJR010000142         4472 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.147, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000142 DAZUJR010000000
VERSION     DAZUJR010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4472
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.147"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(52..522)
                     /locus_tag="ACG804_002776"
     CDS             complement(52..522)
                     /locus_tag="ACG804_002776"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HFS4833641.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(681..1139)
                     /locus_tag="ACG804_002777"
     CDS             complement(681..1139)
                     /locus_tag="ACG804_002777"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0043768 - S-ribosylhomocysteine lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HFS4833642.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(1310..2455)
                     /locus_tag="ACG804_002778"
     CDS             complement(1310..2455)
                     /locus_tag="ACG804_002778"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HFS4833643.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            complement(2468..3385)
                     /locus_tag="ACG804_002779"
     CDS             complement(2468..3385)
                     /locus_tag="ACG804_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent cysteine synthase family protein"
                     /protein_id="HFS4833644.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3813..4376
                     /gene="efp"
                     /locus_tag="ACG804_002780"
     CDS             3813..4376
                     /gene="efp"
                     /locus_tag="ACG804_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HFS4833645.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
BASE COUNT         1377 a          831 c          853 g         1411 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tcttttttta tttttattaa gttaaagaac
       61 ggattcaatt gcagcggtca ttttcaatgg agaagtttgt ggtgcaaatc gttcgattac
      121 tttgccattt ctatcaatca aaaatttagt aaaattccat tttattgctt tagtgacagt
      181 accaggagct tcatttttaa gataagtaaa aagaggatct gtattttctc catttacgtc
      241 aatcaattga tgcataggga aggtaacgcc ataagtggtt ttacaagctt ctgctgcttc
      301 agtcgctgaa tctagctctt gtttaaattg attggaagga aagcctaaga taaccagacc
      361 ttgtgtctga taagcttggt aaagttcttc taattgttta aattgaggtg ctagaccgca
      421 ttttgttgca gtgttaacaa tgattatcgg tttgcctgca tattttttca atgaatagac
      481 agtgccgtct tctaaagtag tttcaaaatt ataaatagac ataaagtttt ctcctttcta
      541 ttttatataa taaaaagagc gctaaactga aaactagcta tttgttttcc cgtttagaac
      601 tcttttcaga caataaatat ttaataaaat acgaagataa gatagctata ttgcttctca
      661 tctttacgtt cttttagaaa ctatgcttct acttcagacc attcatcgcg ttttgctaaa
      721 aattcacgag ccaaagcttg tgcaccttct agtgtatggc tggcagccca gccacattgt
      781 gtttcattgc ttgcaggtac ttcagtagct tcaagaacat ctttcattgt tgcttcaaga
      841 acatctaaaa tgtcttcgta gctttcatga ttcaatacag tcaagtaaaa gcctgtttgg
      901 catcccattg gagaccagtc tacgatgtaa tctgcgtgat tgcggattag ttcggcagtc
      961 aagtgctcaa gtgaatgtag acttggcatg tccatgtgtt ctttatttgg ttgtttaaag
     1021 cggacgtcgt atttaatgat gacatcgcca tgcgcacccg tttttcgatc agctacacgt
     1081 acataaggtg ctttgacttt tgtatggtca agattaaaac tttcgacatt cattctcatt
     1141 tgtaagactc ctatctgttt gttcattcgt tttgatgctt ttcactaaag aattatttag
     1201 tgaaatttac aaaaacgtct ttctacttga ttctaacact tatcgtttcc aaggtgtagc
     1261 aatctgaaat attttttaga tttttctgct aagtcgttta ttgggacttc tagttcttga
     1321 ttctgtcaaa tgcctgagct aaatcgttta tgagatcctg accatactca attcctacag
     1381 aaagacggat caagccgtcc tttatgccag cctcttctcg tttttctttt ggaatagacg
     1441 catgagtcat gacagaagga atttccacta aactttctac gccacctaaa ctttctgcta
     1501 aagtaaatag ttggagtgat tcaacaaatg gaatagcaga ttcttcattt tttaaagtaa
     1561 aagaaatcat tccgctaaag ccgctcatct gctgcttagc aactccatgg agttcatgat
     1621 cgggtaatcc tggatagtag accttttcta ctgctggatg agaaaataga aaatcagcta
     1681 ccacaaaagc atttttttga tgttcctcca tacgaacact tagtgtcttg attccgcgct
     1741 gaagtaacca gctatcttgg ggaccaagta cggctccgat agcattttgg taaaatccga
     1801 tctgatcggc tagatcttta tggttagaag tcactaaacc agctactaca tcgctgtgtc
     1861 cgcctagata tttggtaccg ctatggacaa cgatatcaga accgagatct aaaggtcttt
     1921 gaaaataagg agtagcaaat gtattgtcag caataactat caatccatgt tgatgagcca
     1981 gagtggcact tttttctaaa tcagtaatct ttagaagcgg attgctaggt gtttcaagat
     2041 aaagtgcttt tgtattgggt ttgatggatt gttctatttt atcaagatta ctcgtatcta
     2101 tgatcgtgta ctcgagacca tttttagtaa gaactttgtc aaatagacgg aatgttcctc
     2161 catagacatc atctcctaat aagatatgat cgccagcttg aaaaagagaa aaaacggcat
     2221 gaatcccaga aagaccagaa gaaaaagcga atcctcgaac accgccttcc aaatcagcaa
     2281 tcagttcttc caatgcaaaa cgagtaggat taccagatct tgaatattca tattgtttag
     2341 gctggccgac gccatcttgc cgataagtgg atgtttgata aataggtaca ctgacagctc
     2401 ctgttgtggg atcttcactg atgcctccgt ggatcaattt tgtttgaatg tgcatgtttc
     2461 tttcctccta taagtaaatg ttttttgata aatagcggtc tgctgcgtct ggaaaaatcg
     2521 taacgacacg atgaccaggt ggtaaacgac gaatttctct taatgctgct gcaaaagccg
     2581 caccactcga acttccaact aatagtcctt gttctcgtgc taactgccta gtatagttaa
     2641 acccttctac atcagagatt gtctcgatct gattgattga aaggggagaa agaaacggcg
     2701 gaatgaattc tacaccgata ccctcaattt cgtgaggggc tggatcacca ccatttaaca
     2761 cagagccctc tggttctaca ccgattattc gaatgtcggg atatttttct ttcaaaaagg
     2821 tagaagttcc agcaaaggtt ccaccactcc caattcctgc tacaaaacta tggatatttt
     2881 ctttgatttc atgaaagatt tctggcccta acgtatgata gtaagcagca ggattatctt
     2941 tattttcaaa ttgaagaggc agatagctgt ttgatatctc ctctgcaagt tttttacttt
     3001 tgctgatggc accgatgatt ccttgctcac taggagaatg gatgatcttt gctcccaatg
     3061 ctttcatcaa ttgttgtttt tctaagctaa acttctctgg aacaacaaaa accgttctta
     3121 atttgtatgt gagtgcggcc agagcgatcc caattcctgt atttccggca gttggttcga
     3181 tgatcgtcgt tttttcattg atttttcctt gggcaaatcc ttctttgatc aaataactgc
     3241 ccaatctatc tttgatactt cctccaggat ttaaatattc tagttttgca taaatagcag
     3301 aacctttagg catagaatag tgctgattgt caaagcgata aagcggtgtg gaaccaatag
     3361 cttctgtaat tgtcgagata atcatgtggg cctcctaaaa aaagataata aaaaaaggag
     3421 ctgactatta aatcagctcc ttgaaagaca tagagaaaaa ttgagtagat aaaaagataa
     3481 gttacctggt actcattcta tgaagggcaa ttaatagaca tgacaaatag tatgctgctt
     3541 ttatgcacca tacaacagca acgattcaat tgtttttggt tgctgactgt catgtgtatc
     3601 cctccaagta aaatttttat taacgatagc atgaaaaaaa ataaaagtca aaggcttgaa
     3661 agaaaaaaat atttcgatag catcgtttac ccgtgtttat ttttctgaca aataggcatg
     3721 agaccttaaa agatagagaa tactctagtt ttctggccgg ttgtctgata caataaagtt
     3781 gattatgata aagaaaagaa ggagcaaaaa taatgatctc agcaagtgat ttaagagccg
     3841 gtatgacttt cgtacaagac ggcaaactga ttaaagttct ggatgcaagc caccataaac
     3901 ctggtaaagg aaatacagtt atgcgtatga aactgaaaga tgtccgttca ggtgcaacat
     3961 acgacacaac gttcagacca gaagaaaaat ttgaaaaagc acatatcgac acaaaacctg
     4021 tacaatattt gtacacgatg gatgatacag ctttcttcat ggatttggaa acatatgagc
     4081 aatatgaaat tcctgtagaa acagtagaag aagaaatgaa atatatccta gaaaacatgg
     4141 aagtaaaaat ccaatttttc ggtagcgaag tcatcggcgt tcaattacca acaactgtcg
     4201 tattacgtgt tgtggaaaca caaccttcca tcaaaggtgc aacagtcact ggttcaggta
     4261 agccagcgac aatggaaact ggcttagtag tcaatgttcc tgacttcatc gaaacagatg
     4321 aattgttgga aatcaataca gcagaaggtt cttatgtaaa acgtgcgtca aaataattcg
     4381 ctaacggatt gataagaatt tgaaaacaga gcttgacctc ttgaaaggca gatcatcgga
     4441 tctgcctttc aagaggtttt ttgtggaatc ag
//
LOCUS       DAZUJR010000143         4341 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.148, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000143 DAZUJR010000000
VERSION     DAZUJR010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4341
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.148"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            88..1389
                     /locus_tag="ACG804_002781"
     CDS             88..1389
                     /locus_tag="ACG804_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFS4833646.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            1416..1676
                     /locus_tag="ACG804_002782"
     CDS             1416..1676
                     /locus_tag="ACG804_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HFS4833647.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(2675..3910)
                     /locus_tag="ACG804_002783"
     CDS             complement(2675..3910)
                     /locus_tag="ACG804_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFS4833648.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
BASE COUNT         1268 a          692 c          891 g         1490 t
ORIGIN      
        1 atttcttaat tatataatta gttatgaaca ttctttgcgt tgtcatgcaa tgaatggttc
       61 atattttatt gaaaaggagt ggttttagtg gaaaagctga tgaaatgggt cgaagagaaa
      121 cttgtcccac caatggcaaa aattggtaca cagcgtcatt tattagcaat tcgtaatggg
      181 gttgtttcaa cattgtcatt gattttgatt gggacatttt ttatggtctt tatcaattta
      241 ccgtttcctg gatggaatga atttattgcc ccttattcgg caacgattgt tttacccttt
      301 aggatgacga tgggattgat ggctatttat gcaacttttg ttatgggttc ggatctagct
      361 aaatcatatg gattagatag tgtgacaggt ggtatattat ctttaggaac gttctttatg
      421 ttacaagttc ctgtaaacgt tttaactcct gaagaggcac ctcttggctg ggtcttacct
      481 atgagttctt tgggagcatc tgggatgttt gcggggatct tatctatgat ttttgcagtg
      541 gaagtatatc gtttctttaa aaatcgaaat attactatca aaatgccaga acaagtgcca
      601 cctgctgttg cccgtagttt tgaggcattg attccaggtg cagtcatttt aacaattact
      661 tggctgattc gaagcgtcgc gggctttgat gtaaacgctg ccttattatc gttattcgag
      721 cctttaacca atattttagg gaataatttg cttggtgttt tactaccaat gtttttgatc
      781 catttgttgt ggtcatttgg tatccatggc atgagtattg taggggctgt tgttcgtcca
      841 atgtggctga tcatgttgga tgagaatgca aaggcattgg cagatggtac agctgccacc
      901 caattaccct atatcgctcc tgaacagttt tatcaatgga cggtaacaat tggtggtgca
      961 ggagcaacga tcgtggtatc tgttttgttt atattcttct gtaaatcaaa attcttgaaa
     1021 gaggttggtc gtttttctat tattcctggt atcttcaata tcaatgagcc cataattttt
     1081 ggagctccta tgatgttgaa tccttacatg ttcatcccgt tcaacttagt tcctttagtt
     1141 ttgactatta tcagttattt tgcagtcaaa ttagaaatgg tcaatagatt tactgttttg
     1201 ccaacatgga cattaccagc tccaatcggc ggttatcttt cagcaggaaa tgactggcgt
     1261 gttgttatct tgatcatgat caacacattg atagcattta ttatctatta tccatttgta
     1321 aaagcttatg ataaaaagat gctgtcagat gaacaaagtc gtggagaaaa cgaagtccag
     1381 actgtctaag tttggttttt agaaggtggg aaacaatgta ttggctgatt ttattttttg
     1441 tttttatctt tttattaacg gctagtcacc ttatattgaa tatgctagct acatatcata
     1501 ttcaaatcaa tcgatggatt tgggcactgg catcattttt gatcgtgatt cttccaaaga
     1561 tcattgtacc gcatatgaat gttttgtttt catgggggac atatgtactt tgtggaattt
     1621 ttgctatcaa ttttatgatc gagcagcata gatggtttgt cacatcgaag ctttaaatgt
     1681 tctaaaagtg gttgtaacag aagtggttag cttcaagaaa taagaagaaa tttacgaaaa
     1741 ttgcttctta aatttttgtg aaatgttggc ttatttttcg tttggttgaa cttattaccg
     1801 cagatgcaag cttttgacca ccgtttattc ggaatatggg actgtgacaa ggcttttgtc
     1861 acagcccttt tttacataaa gattattatt gttttaactg ttttggcaga aagaaggagg
     1921 aaaaaatgga aattttatca gcaatggatt tagaattagt agatctacta ccaaagtgat
     1981 caagtcaaat atagatttgg gagcttacaa ccatatagta ggggctgcag tatggtgtat
     2041 gaatggtaat atgtatgatg tgagtgttta ttcaaatcat gaaacgtgta tagaaataat
     2101 tgtgctggga atagcaatca gtcatggtga acgtgacttt tagtgtatcg ttgctgacga
     2161 catagaacat tctgacatga tctactcaat atgtggggat tgctggcagt ttatatagga
     2221 gtatgcatcg gattgcgaga tcattgtctc aacagaagag ggaggttgat tatcaaagat
     2281 aaagtggtaa atcctacatt tgatttagta attgttgagg ggactagcgg cacaaatctc
     2341 tacaaagcga tgcttctaga tctatatgac acattttaag aaaatgtatt tgcctaatta
     2401 ttatggtctt tcttttgaag aaacgttgag atgatccaac cagagaaagg tgtcaaagaa
     2461 tttgactaag aataaatggc agacgctacc tatgctcatt tggatagcgt cagatctttt
     2521 attttaagga tgattttgtg ttttttagac accgtaattt aagtaactct aacttttcaa
     2581 tccactattt actttttttg tattttcact gtctgggtct cgaatagcga aattactgat
     2641 gagtctctat taaaaaagct ttttctactt gaaactatat tgggtggttg ctcaggaagg
     2701 tttcgatttc ttgaattgct tgttgtggac catttattgg aaaaacggct tgcagcgtgc
     2761 gtgcctgctg acgaatcttg ggtgaagaaa cttcgcgcag agcaatctgc agttttcttt
     2821 cagtcactgg ttttgtgagg gcgattgcgt ttccgtattt tacacaatag tcaatattac
     2881 agctttgctc aaattgcatc cccacaccga taaacggttt gccggattca caggcagttt
     2941 ggacggtccc ttccccgccg tggataaaag aaaaatcaat gaattcatgc aaaagatgac
     3001 tagacagata ttctgttatt aaaagatctt ctgagtcaga ttgaatgtca tcaagcagat
     3061 agtcaatagg tgcaataacc gctagatccg gttgtttttg taagaagaac aaaattttgc
     3121 gtaacatacg cggattgcct gaactaccca ttgcgaaata gataatacgt tttctttctt
     3181 gttgctttcg ctgtataaaa gttagcactt cttcaggcaa ggaagtactg agcttagcaa
     3241 aaattggacc aacgattcga taattttccg gcagctgttc ttcttccaaa aatagtttag
     3301 gcgttgtgat gagatttaga tcagcatcca tcatttgtaa acttgttttt ggtaaaggaa
     3361 gcatttcttt ttgtgcagcg tgtttgaagg cattggggat ccatcgggta tttactatac
     3421 gcttttttgt ccagtgccaa aggggattgc ttaaagggcc gaagaaacgt aactcgtggg
     3481 gcatcagcgc atgctctgat tgaaaaaaag gttcactcaa agcatagggt ttaacatata
     3541 ctaaaggaat ctttttattg cgggccgata aaaaaattgt cacattcgaa cctgtcacaa
     3601 tcagtcgagg ctcaaactta gcaatcagac tctgttcact agtgatacga gaggcaacca
     3661 tttctttggt aaaagggttt ttaagtgtac gcaactggtc aaattttatg atttgttctt
     3721 cttgtttttt cgtaaggatc ggcgctagta aatgatactc aaagccactt tctgtgatca
     3781 aaggagcaaa agttttagaa aagccaaaga atacacagta ataacggtct ttcatagctt
     3841 tggcaacctc aatcattcgt gttgtctcag ctaaattgaa tactgcagga gcaaaaagaa
     3901 ttgtcttcat gaaatcctcc ttattggaat gagtctatcc cttcgtttct tactagtata
     3961 ctaaaaaaca cagcgttcga gtagcctatg tatattttga atattaaact gtctctcgct
     4021 gttttcacaa cttctaaatt taaattttgt aatcaagttg aaactccaat tttcaaaaaa
     4081 acacgcaaca attttttgat cgatttatat gttgtgccag ataaatacga gaagttgtgt
     4141 cattaaaaat aaacatgaga acataaaaaa ataaaataat tatattaatt gataggtgtg
     4201 ctgtcgtcat tatacacacg taagaaagaa atagttatgt ttaaaaatat tcttagactt
     4261 tctcgccatg acaattttca ctatgtgtta taactgtaaa cgataattat tcagataaca
     4321 caaaaagaaa tcaaggagca g
//
LOCUS       DAZUJR010000144         4282 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.149, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000144 DAZUJR010000000
VERSION     DAZUJR010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4282
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.149"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            75..503
                     /locus_tag="ACG804_002784"
     CDS             75..503
                     /locus_tag="ACG804_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="HFS4833649.1"
                     /translation="MGDSEETHIQHTFDSFCKKVVCNEALNIQKKYARFRQRQISMEI
                     LEQKGLGTEFYYLEPNLNSSGTFIVLGMKIFISNEELANAIAALPSQRQEIIFMSFFI
                     GLNDREIGDIIGKSLGSVWYQRQMALEELGKYLGVKYEAK"
     gene            490..732
                     /locus_tag="ACG804_002785"
     CDS             490..732
                     /locus_tag="ACG804_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4833650.1"
                     /translation="MKQNKRYIPFIPLTTIKAAASGDSIAMSIVLSKYQNYISRLAMK
                     PVYEEEKGMVMYVDEYMRRQLETKLIEKILEFDTTR"
     gene            complement(1032..1247)
                     /locus_tag="ACG804_002786"
     CDS             complement(1032..1247)
                     /locus_tag="ACG804_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833651.1"
                     /translation="MKQGIADIKIIKEILEKSTANAIAFGTGINLSTVKKLKSGERAE
                     EKLNLADAIKITEFGMKNMPTKIEIWK"
     gene            1354..1668
                     /locus_tag="ACG804_002787"
     CDS             1354..1668
                     /locus_tag="ACG804_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4833652.1"
                     /translation="MELEVKTNVNSLEIEFYSILQKKLEDYTEKLLAVSHLPLVLTNT
                     DLKRLFQISDSTLNRLVKLGEFPPCWYGIRGHYFRDDVLEWMRKSDSNDYREKLRLLR
                     SL"
     gene            1772..2950
                     /locus_tag="ACG804_002788"
     CDS             1772..2950
                     /locus_tag="ACG804_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4833653.1"
                     /translation="MEKTDRFKKQISSTGRITWYFQAYRTTRRGFNSKREAQLAYLEM
                     EKQQRLKKKIVASNDKFSVVGEQWFQYYRSLNEQKEITYDKREEQLKIIVRWIGDKKL
                     SDLTPECLQELLFTLKECGVNGTNVGYAKNSLQSLIQVLNMIFKYCQRKNLISENPMK
                     SVRMPKYQLTVTDLKEAINNIEDKFLTVDELRTFLNYGIVHEELPMSVLFHVLFYTGC
                     RVSEALALQPGDIDFKRNEILFYKQTAVKGKSKDFRIETTKTVSSARRVLVTPLVMEK
                     LQQLIKALGEMRQHYRFIIEETYLFVYLDSSKRGVPYRREYVNDHVKRCVNRSGINKP
                     FHTHLARHTMASLVAEHCSWEVLKDRLGHTDQTTSKIYRHLTSNEKVKPLIAFSSLES
                     "
     gene            complement(3131..3316)
                     /locus_tag="ACG804_002789"
     CDS             complement(3131..3316)
                     /locus_tag="ACG804_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833654.1"
                     /translation="MLEYSGFFIKAVTLKKDIIIVLFFLLLLIGRFILIHYSPLPIIK
                     EKTGSGCSNYMLRKKNP"
     gene            3353..3646
                     /locus_tag="ACG804_002790"
     CDS             3353..3646
                     /locus_tag="ACG804_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HFS4833655.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            complement(3734..3880)
                     /locus_tag="ACG804_002791"
                     /pseudo
     CDS             complement(3734..3880)
                     /locus_tag="ACG804_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332517.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamate
                     endopeptidase"
BASE COUNT         1466 a          646 c          822 g         1348 t
ORIGIN      
        1 tcctagattg tagtaataat ggaaagggat agaagtaaaa cgagttgaat gaattttttg
       61 agggggagaa tattatgggc gactcagagg aaacccacat tcaacatacg tttgacagtt
      121 tttgtaagaa agtagtctgc aatgaggcgt taaatattca aaagaagtac gctagatttc
      181 gccaacggca aatatcaatg gaaatattgg aacaaaaagg gttaggtaca gagttctatt
      241 atttggaacc aaatttgaat agtagtggta cttttattgt ccttggtatg aaaatcttta
      301 tttccaatga ggagttggca aatgcgattg cagcattacc tagtcaaaga caagaaatca
      361 tttttatgtc cttcttcatc ggtcttaatg atcgtgaaat tggcgatatt attgggaaaa
      421 gtctcggcag tgtttggtac caacgacaaa tggctttgga agagctagga aagtatttgg
      481 gtgtcaaata tgaagcaaaa taaacgatat ataccattca taccactaac gacaatcaaa
      541 gccgcagctt ctggtgattc aattgccatg tccatcgttc tgtcaaaata tcaaaattat
      601 atttcacggt tagccatgaa accagtttat gaagaagaaa aaggaatggt tatgtatgta
      661 gatgaatata tgcgtagaca actggaaaca aaattgattg agaagatact tgaatttgat
      721 acaactcgtt aaagtatttt ttccctttcc ttttcattct atggaagttt tttatcgggt
      781 caaaataaag gatttccata ggctgaaaat agcctagcgc tctttgacaa atgaatagca
      841 aatctatcag tacatgtaga ttttgattct ctagttacgc catgacaagg ttagctttta
      901 agcgacaaat tttaatatga gaatcgcgac tacgataatg atacttccgt aaccaaatcg
      961 gcccgccatt actgggggga ggtgagattc ctatgtgctt tggcaaaaca gctgatagat
     1021 cagaaaaact actatttcca tatttcgatt ttggttggca tatttttcat gccaaattct
     1081 gtgattttaa tagcatcggc aagatttaat ttttcttcag ctctctctcc acttttaagt
     1141 ttttttactg tactcaagtt gattcctgtt ccgaatgcta ttgcattagc cgtagatttt
     1201 tcaagaattt ctttaattat ttttatgtct gcaattcctt gtttcatatt aaaaattcct
     1261 cttttctagt ccgttttgat ggagtactgg agtgtttttt tacaatttta aggggtaccg
     1321 tggtggtcgt tttgattttg agagagaagg gtgatggagt tggaagttaa aacaaatgtt
     1381 aattctctgg aaatagagtt ctattcaatt ttacaaaaaa aactggaaga ttacacggaa
     1441 aaattgcttg cagtcagtca tttacctctg gtattaacaa atactgattt aaagcgacta
     1501 tttcagataa gtgatagtac actgaaccgt ttagtaaaac ttggtgagtt tcctccctgt
     1561 tggtacggga ttcgaggaca ctattttcgt gatgatgttt tagaatggat gagaaagagt
     1621 gattcgaatg actatcgaga aaaattgcga ctacttcgat ctttataagt tacattttct
     1681 ttctaagatg cggtacaatg atgacataga tagaaagatt tccaaagggt ttctgcttgt
     1741 tgggttcctt caaaatagga ggaatcaata aatggaaaaa acagatcgat tcaagaagca
     1801 aatcagttct actggtagga tcacatggta ctttcaagca tatcgaacaa caagacgtgg
     1861 ctttaattca aaacgtgagg cgcaactcgc ttatctggaa atggagaaac aacaaaggct
     1921 taagaaaaaa attgttgcaa gcaatgacaa gtttagtgtt gtaggtgagc aatggttcca
     1981 atattaccgt tcgttaaatg aacaaaagga aataacctat gataagcgag aggaacaatt
     2041 aaaaattatt gttcgatgga ttggtgataa aaagttgtct gatttgacac cagagtgcct
     2101 tcaagaattg ctttttacct taaaggaatg tggcgttaat ggaacaaatg ttggctatgc
     2161 caaaaatagt ttacaatcac ttattcaagt tctaaatatg atttttaaat attgtcaaag
     2221 aaagaatttg ataagtgaaa atccaatgaa gtctgtgaga atgccaaaat atcagttaac
     2281 ggtaactgat ttaaaagaag ccataaataa tattgaggac aagtttctta ctgtcgatga
     2341 attgagaact tttttgaatt atggcattgt tcatgaggaa ttaccgatgt ctgtactttt
     2401 ccatgttcta ttttacactg gctgccgagt cagcgaggcg cttgctctac agcctggaga
     2461 tatagatttc aaaagaaatg aaattctgtt ctataagcaa acggcagtta aaggtaagag
     2521 taaggatttt cgaattgaaa ctactaagac agttagttct gctagacgag ttctagtaac
     2581 tcctctagtt atggaaaagc tacaacagtt gattaaggct ttgggtgaga tgaggcaaca
     2641 ttacaggttt attatagaag aaacatattt gtttgtgtat cttgattcta gtaaacgtgg
     2701 tgttccttat cgtcgagagt atgtaaatga tcacgtcaaa cggtgcgtga atcgctcagg
     2761 aattaataag ccatttcata ctcatttagc tcgtcataca atggcaagct tagtagcgga
     2821 acactgtagc tgggaagtct tgaaagatcg cttaggccat actgaccaaa caacttcgaa
     2881 aatttatcgc cacttaacgt caaatgaaaa ggtaaaacct ctgattgctt ttagttcttt
     2941 agagagttaa aaaaacggtg aaagcactgg tattacagga ttcttgaaaa acgatttttt
     3001 aacaaattag tcaatatgta gtcagaggta ataaaaatcc ttttatatca atactttaac
     3061 gacttttcac aagtatcaaa gaaatccgtc gttaatcatt gttatcagac tgagaaagaa
     3121 cccttggtat tcaagggttc ttttttctta gcatgtaatt tgaacaccct gatccagttt
     3181 tttctttaat tattggtagg ggagaataat ggattagaat aaatctacct ataagtagta
     3241 gtaaaaaaaa gagcactatg ataatatctt tcttaagagt aaccgcttta ataaaaaatc
     3301 cagaatattc taacataaat ggagtattct tagaatcaaa aggagaaaga agatggttta
     3361 tacttatacg gagcaagaaa agatgaaagt tttagacaca ttcatgaatg atggaaaagt
     3421 aaaacaagta ccaagttcaa caaaaaagaa atacatccta ttgaaagaag tcttgaaacg
     3481 ctttgaccat ggagtgactt atacagaaac agaggttaat tcgatactgc tgaacgtatt
     3541 ttctagtggc gattatgtcg aacaaagacg ttatctaatc acatttggct ttttcaaaag
     3601 aagttcagac ggtcgggcat atcagatgat gggaattgaa aattagaagt tttaatttat
     3661 actcattgaa aaaagttcaa gtatgcgata ttggttctac accgcatact tgaacttttt
     3721 ttgtcatctg tatctataat acaaagccaa gaacgttatt caaaatatgg atagctatga
     3781 taaaagctaa tgagcgattc gcagttaaat aagcaatcgt cagtaaaatc gttccaggag
     3841 cgtacatgaa aaaatcaatt ggatgcgtta catgaataaa gataattctc ttttatttgt
     3901 acgaataaat accaaaacgt acctcctaaa attagatttt ggacagatgc cctttaaaaa
     3961 gataacaaga tttcgttctt gaaacaatat atatgctttt attccaatga ggttgtgaaa
     4021 acagtatttt gtcctgagcg ttagaaaatt gaaaatgggg aatagcaact cgtactttac
     4081 cattttttaa gtgaatacaa gatcagctaa ttgaacaccg tttattcgtg atgagggaca
     4141 caacactgca gtcgacacat ttctctttta tgttcaaaga taacaaatat ttaaaacaaa
     4201 gaaaaatagt agataatccc gtcctaactc ttttattctt ccctcatagc ttccaaattt
     4261 aagcaatact tcaattaatc aa
//
LOCUS       DAZUJR010000145         4173 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.150, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000145 DAZUJR010000000
VERSION     DAZUJR010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.150"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..808
                     /locus_tag="ACG804_002792"
     CDS             <1..808
                     /locus_tag="ACG804_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HFS4833656.1"
                     /translation="VHYFFTGKIEDLFHEPLIEYTGNLSKTIEQIKIDNLLSQNYDPE
                     IYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDTIRSEKNYSIIVFEKLAQ
                     TSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIVYYTKEIGKTKIEHLSPL
                     ISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMHITIYNYISKRKISTAKI
                     MLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLGLVDNFNNIS"
     gene            905..1258
                     /locus_tag="ACG804_002793"
     CDS             905..1258
                     /locus_tag="ACG804_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833657.1"
                     /translation="MSCFVESERLSNGNNSVLNEYDKVVINKVKSLCEEARESISHIN
                     GSNFKQTLFNLIKLDAKISSYLFFLIHDEFMDYQKLDQLIERESWEDYYVGLTFSEKL
                     NNYKLIDYKYLSESN"
     gene            1875..>4173
                     /gene="esp"
                     /locus_tag="ACG804_002794"
     CDS             1875..>4173
                     /gene="esp"
                     /locus_tag="ACG804_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HFS4833658.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLVGVGLVLGTT
                     ELVQAQDEISPSTPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEEPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSASAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGKKVADLAIERRKDHENYGVGSITDNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSILDVYNKDFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPA"
BASE COUNT         1536 a          570 c          785 g         1282 t
ORIGIN      
        1 agttcattat ttttttactg gaaaaataga agatctattc catgaaccgt taattgaata
       61 tacaggaaat ctaagtaaaa ctatcgagca aatcaaaata gataatctgt tatcacaaaa
      121 ttacgatcca gaaatatatc tgtttcttta tgaaaataaa atactggaat atgttaaaaa
      181 tggagatatt cgaaatttag aaaacatggt ttttaatctg agtaatggaa taattccaag
      241 tgttagtgga gatacgattc ggtctgaaaa aaattattct atcattgttt ttgaaaagtt
      301 agcacaaacg tctataacat taggaatgga tataatagaa gcgtatcaaa gtagagatgc
      361 tttgatacaa gaaaacgaat tagctgtatc gttacctgag gtcttaaaag tgagggattc
      421 tgggattgtt tattatacta aggaaatcgg aaaaactaag atagagcatc tttctccctt
      481 aatttcttct gtcgttcaat tcatcggctt aaatatctat aaaagaatta ctgtaaagga
      541 aatagctaat tatttttctg taagtgaaac taaattaaga gaaagcttta agaatgaaat
      601 gcatattacg atttataatt atatctctaa gcgaaaaatt tctacggcta aaataatgtt
      661 gaaatcaaac catactatca gtgaagtttc tttaggttta ggattttcag attcttcaca
      721 cttttcgaga gtattcaaaa agtacgcagg tgtatctcct aagcaatatc aattaggttt
      781 agtggataat ttcaacaaca ttagctgaga ggttttattt tattatgaga ctatatcatt
      841 tacgtagttt ggaggagttg aggaaattgg attttaacaa aaaatttttt gggaaatttc
      901 tgatttgagt tgtttcgtag aatctgagcg tctaagtaat ggtaataata gtgtgttaaa
      961 tgaatatgac aaagtagtaa ttaataaagt aaaaagttta tgtgaagaag ctagagaatc
     1021 tatcagtcat attaatggta gcaattttaa gcaaacatta tttaatctga ttaagctaga
     1081 tgctaaaata tcaagttatt tattcttttt aatacatgat gaatttatgg attatcaaaa
     1141 attggatcag ttaattgaaa gagaaagctg ggaagattat tacgtgggtc taactttttc
     1201 agaaaagtta aacaactaca agttaataga ttataagtat ttgagtgaaa gcaattaatt
     1261 attcatgtag agtactagac actttaaata tggacaattc aattataaag aaaaagaatc
     1321 aataatttaa tgaggctgtg acaaatgtca ttttttgttt cgctaaaaac gagtgaaaaa
     1381 atgttgataa ctccaatcat tcgtttaaga ttctaggaat cattcaggaa tgctgtgaaa
     1441 ccgatacttt ataattataa agaaggtgat ttcaaattcc gaagaaggaa tttgaagtca
     1501 cctttttact tatgtcacag tctcattcag taatgcggga taaggctcct tattccgcta
     1561 tttgaatact ctgaagttta atctaagaaa gagtaatatt ttgaaaacat gcttcatcgc
     1621 atagaaatga acttaatttc agaaagaata catacatatc tttttatatg ttttcagctg
     1681 ctgaatggtt aaaaagcaca aatatccgaa aaaaacatga agaaatgtac tttttttgtt
     1741 gtaatgtgca tgaaattctt taagtaaact agttaacata agtttagtaa gattcctatt
     1801 ctgtgaataa tacgtatcag atttatcttt tattcttact aagaaaataa ctattaaggg
     1861 agttgatttg aataatggtt agcaagaata ataagagagt atttctagaa aaaacaaaga
     1921 aacgagtatt gaagtacagt atcaaaaaat taagtgttgg ggttgcatct gttttggttg
     1981 gtgttggtct tgtcttggga acaactgaac tagttcaagc acaagatgaa atttctccaa
     2041 gcaccccact tgaaacagcg ataagctccg tacaagtagg tgacaaagta gcttcgggga
     2101 atacttttca ggagaatcct ggttatacga aaaattataa cttttcggat ttacaattta
     2161 gtcctcaaga actaactgga gacacactaa aaggcaatac aattggattt gaagtttacg
     2221 gaaaacataa tattgcagca tcaactaaaa actgggaaat ccgtcttcaa ttagatgaac
     2281 gattagctaa atatgtagaa aaaattcagg tcgatccaaa gaaaggaatt ggatcttcta
     2341 gacggacctt tgtaagaatt aatgattcgc tgggtagacc tacaaatatt tggaaggtca
     2401 attatattcg tgcaagtgat ggattatttg ctggggctga aacaactgat acacaaactg
     2461 ctcctaatgg ggtaattacg tttgaaaaga gcttagatga aatttttaaa gagataggca
     2521 tagacaatct caagaccgat cgtttaatgt atcgaatcta cttggtaagt catcaagacg
     2581 atgataaaat tgtaccaggt attgatagta cgggctactt tttaacagat tcagatgatt
     2641 tctataatag cttagatgta tctgaaaata atcctgacca gtttaaacat ggatcagtaa
     2701 gtgcaaaata tgaggaacct aatactcaaa caaaagatgg ttcaggatcc acaggtgcta
     2761 atggagctat aatcttagat cataagttaa cgaaaaatta taatttctca tattcagctt
     2821 ccgcaaaggg cacgccttgg tatgctaatt acaaaattga tgaacgatta gttccatatg
     2881 tagcgggtat acagatgcac atggttcagg ctgacaaagt aacatatgat gtttcttttg
     2941 aatcagggaa aaaagtggct gatttagcaa ttgaacggcg caaagatcat gaaaattatg
     3001 gtgtaggttc aattactgat aatgatctta ccaaacttat tgattttgct aatgcaagtc
     3061 cacgtccagt cgttattcga tatgttttac aattgactaa gccattagat gaaatcttag
     3121 aagatatgaa agcaacagca caagttgaag aaaataaacc atttggtgaa gatttcatct
     3181 ttgattcttg gttgtcggat acgaataaaa aattaatcca gaacacttat ggaacaggtt
     3241 attattattt gcaagatatt gatggtgatg gaaaccctga cgataaagaa gagagcggag
     3301 acacgaatcc atatatcggg aaacctgaat tagaagaagt atatgatgtt gacacaacag
     3361 ttaaggggaa agtattcatc cacgagttag cgggaacagg tcacaaagcc caacttgttg
     3421 ataaagaagg tactgtatta gcagaaaaaa ctatcgctcc aaatgaaaaa gatggggctc
     3481 caatttcaga tactgtagaa tttgaattta cgggtgtaga ttcaagtaaa ttaatcgcga
     3541 aagatgaatt aaaaatccaa atcgtttctc caggttttga taaaccagaa gaaggttcaa
     3601 ccgttattaa ggaatcacca aaagcggttg ataaacaaac cgtggtagtt ggatttaaac
     3661 cagatgctaa agaatcaatt cggaataata aaaacttacc tgaagatgca gagtattcat
     3721 ggaaaacaga gcctgatact tctaacgtta ctgatagtac gaaaggtatt gtaactgtta
     3781 agatcggaaa tcgaactttc gacgtggatg tagagtttgc tgtaaaagct tctcaagcta
     3841 tggaaaatga tgcaacatac gtacctataa caacaactcc agaaacgaca gttcaaagtg
     3901 gaaaacctac atttgataaa ccagatgttc ctttagctaa agatgccttt tcaattttag
     3961 atgtctataa taaggacttc ggtaatgcaa gtgttgatgc aaatactggt attgttacat
     4021 tcactccagc taaaggtgta ggagaatcgg agccgattac tggaacaatt cctattaaaa
     4081 ttgtttacca agatggttct gtaggcacga ccgatttagc agtaactgta agtaaagata
     4141 tttatgaaaa tccaggagaa aacattcctg cag
//
LOCUS       DAZUJR010000146         4079 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.151, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000146 DAZUJR010000000
VERSION     DAZUJR010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4079)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4079)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4079
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.151"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(445..807)
                     /locus_tag="ACG804_002795"
     CDS             complement(445..807)
                     /locus_tag="ACG804_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HFS4833659.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            1030..1782
                     /locus_tag="ACG804_002796"
     CDS             1030..1782
                     /locus_tag="ACG804_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFS4833660.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWLSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(1922..2845)
                     /locus_tag="ACG804_002797"
     CDS             complement(1922..2845)
                     /locus_tag="ACG804_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4833661.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYQKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(2860..3132)
                     /locus_tag="ACG804_002798"
     CDS             complement(2860..3132)
                     /locus_tag="ACG804_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833662.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
     gene            3809..4039
                     /locus_tag="ACG804_002799"
     CDS             3809..4039
                     /locus_tag="ACG804_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833663.1"
                     /translation="MMEDFIRKNISDEYADFYEQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
BASE COUNT         1372 a          744 c          654 g         1309 t
ORIGIN      
        1 tattcaatgt atccgagaca cgaagaaatt agcgttttct atttttctta cttgataaaa
       61 taagtagatt ttcctactac aatcgtagcc gttaagatac cgatgattga acaaatataa
      121 ccaaatgtct ctacaacata atcaatggca aaagtttttg aagcaataat acgtctttcc
      181 ttttttgctt cttatcccca aagaaacgga tataacttat tatgtattga atttttttgg
      241 aaaggcgaat tatgacaaga tataccttgc gttgaaaaaa ctcgcggaaa aaatatcaca
      301 cgtttttaaa aagatacaaa gtaagaaagc agctgtcaat agaatggaaa caaaaatggc
      361 gagacatcaa tcagtctcgc cttgtttttt attgtataca ttagatatgg agcaggttac
      421 cataaagatg attattagtc gttattaaat agaatccttc gtattttttt gttctatcac
      481 tacaatatct ttatttggac gtttgaattg tattccggca cgttctagct cctgtttcac
      541 tcctacatgg actttgacat cttctcgtgt catttttaaa acgtgatgaa tcgcatagtc
      601 gatttcttgc cttgtgattt ttttcttcgt attgatcatc acgacttgct ttttatcata
      661 tgtgtctacc aatagcagtt gtgttcgatc taacgaaaat aatttgtaat aattaatagc
      721 cgtattccca aaaaagaatt ccactacttt aggataaaat gtcttaatat ttaaattact
      781 attcacaggt gtttcgatta gcttcatctc attcctcttt tctatatagt cgatttagat
      841 ccaatcttaa gttatgttac catctttcct agcattaagg aatcggttac aattgaacct
      901 ttaaagacaa aaggatttac cttttatcac ttaatagtat aacataattt catgagaaaa
      961 aaatacaatt ttttcttgac catctcgtta cgtaaaggat tatgcttaca tttgtcagga
     1021 ggaaaaataa tggagtacac aataaagaaa atgtcagaga tatcaggagt cagtccgaga
     1081 accttgcgct tttatgatga gattggactg ctaaaaccag ctaggatcaa ttcttcaggt
     1141 tatcggattt atggcaaaaa agaagtcgat cgtctgcaac acatcttatt ttatcgaaca
     1201 atggcattca agttggatga tatccaagag gtcttagaca atccatcttt tgaccaccag
     1261 aaagctttaa tcaagcatca gcaaatgttg ctggaaaaac gggcacaaat cgataccctc
     1321 ttgacaactg tccaacagac acttgatatg tacgaaggag gaagaaaaat gagtgacaaa
     1381 gaaaaatttg aagggtttaa acaacaaaag ttgaaagaaa atgaagaatc ctatggacaa
     1441 gagattcgac aaaaatacgg aaaaaaaaag gttacagcat ccaatgaaaa atggatgaat
     1501 atggataaag aaacgtatga agaaatgcaa actgttgaaa agcagatgtt atttgatctc
     1561 actctttact taaaagaacc agaagatgaa agcttagcag accgtatctt ccaagctcat
     1621 aagaagtggt tatcttacag ctggcctgaa tatcagccaa aagcgcataa aggactagga
     1681 atgatgtacg aagccgatga acggttcact gcatattatg acgagcgaag tggtcatggt
     1741 gcagcaaaag ctttaaatga aattatccaa aaaaaggcgt aatcttttac atgatccaac
     1801 aaaaaagtac acgtaaaatg acctaataac aaaacagcag acacccaagt tagattttta
     1861 tgctaacttt tggtgtctgc tccattcttt cacaagtttt ttcatcctac tttaaatata
     1921 ttcatcgttg aataaacgta taaggtattt tcactttatc ctttttttct gtaagaaaca
     1981 attgaaatgc catttctccg caagcttcca gatggtggtc gatggttggg aaaccaagaa
     2041 gctcgctgat cagcaaatta tcgcgtccaa tcaccactgg tgtcttatct tgcagatagc
     2101 tttgcaagat gcctgctgca accatatccg aatttgtaaa gacaccatca actccaagct
     2161 ctttaaaaaa gaagcctgct tgttttcctt tctctgcatc tatacaatcc caaaaaacaa
     2221 gtgattcatc aaaagatgga aaaagttgat gacatagctg caaagtgatt tttgagttat
     2281 aacttagcct gccacttcgc cccaacgtga tgcccaattg ctttatacct tgctgcttca
     2341 aataagtaag accttctgta attgattgtt ctcgatcaat aaagacacag cttgcctgtt
     2401 ttcccttgat ttcttcacaa aaaactagag gtccatattt ttgatatgcc aataaatcat
     2461 ctagtgtatt ggcacgagac gtaatgatca atccatcgaa agctttagct gcaaattctt
     2521 caagatacct tcgctctttt tctttctgat agcccgtcgg taaaagtgtc actttgtaat
     2581 cataatcaaa cgctgcttca atgatcccac tgatcaactg atcaaaatac ggatgattgg
     2641 tataaggcag aatcactcca atgcttttcg tttttccata acttaactgt ctggcatttg
     2701 cattagggat ataatcgact tctttcatga ccgcaagtat ttctttcctt ttttcctcat
     2761 ctacatatgg atgtccattg attacacgtg aaatagtaga aactgaataa cctgtgagct
     2821 ttgcgatatc tcgaatgttt gccactgctg cttcgccacc tatacaaaaa gattttcttg
     2881 taaatagtct accacagctg gaccgcattc aaaaaactga tacatttttc cttcatgcga
     2941 aaaactgatc cgctgcccgc cccaatatat atcttttgtc aaattttcga tttcattcat
     3001 tggtatttct tttactatat tcctattcaa cccttgaaaa ctgtacaacg ttaatacgga
     3061 tcccttgaac tcgacaaacg cataaaaata attgttcgtt gtgccatctg ttatctctac
     3121 ataagtattc attgcaagcc ctccttttga tactttgagt atagtgtatg aaacgcgtct
     3181 catagcaagg agtttgtttt gccaaagaaa agttttattc ctctttcatt attaccaaag
     3241 tctcttattt taaattgaat acattataat gatactgtaa atatatcttt attattagtg
     3301 aatggatatt tacttttaat agataaaata ttataactat taaaaataac tattttcatt
     3361 ataattacac acaaaaaaga gcgtgagaca aaagtaaaga acacttttgt ctcacgctct
     3421 aaacacgtat aaacagcgga agcagaagca actccttcgg aaataagctg aaattcacaa
     3481 aaatttgaaa agcaatttcc gtgaatttct tcttatttct tggagttaaa cgcttctgtt
     3541 ccagcctctt tttatctgtc tttcactaat gatcagttgt agataagcaa gttgcttttt
     3601 cttacatcat accgcccatc aagacaaacg tttttagctt gtacgtactg gacaaaaatc
     3661 ccattatatc aagaaaaaac aacgttgata atacttaaaa ttattaggct agaacggact
     3721 agtaagagtt ttttgcccct tttttgcccc tcaaatatcg ctttacagcc agaacataag
     3781 ttcgtataat cgttttgagg tgatttttat gatggaagac tttattagaa aaaatatcag
     3841 tgatgaatat gcagactttt atgagcaaag cagcaaaaaa gataaattcc agatggatgt
     3901 ttcaatttta gctatattag ctttttccga aaataaacaa cctgtaactg caaaaaaaga
     3961 aacagtattc tctgaaggca aaataaaaac tcgatatata ttagaggtag aaactaagtt
     4021 taaaaataga tcggagtaat ggctatgctt tttaatgaga cgcaattatg gtttaaatt
//
LOCUS       DAZUJR010000147         4069 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.152, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000147 DAZUJR010000000
VERSION     DAZUJR010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4069
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.152"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            85..1434
                     /locus_tag="ACG804_002800"
     CDS             85..1434
                     /locus_tag="ACG804_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFS4833664.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(1562..2152)
                     /locus_tag="ACG804_002801"
     CDS             complement(1562..2152)
                     /locus_tag="ACG804_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HFS4833665.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            2299..3651
                     /gene="brnQ"
                     /locus_tag="ACG804_002802"
     CDS             2299..3651
                     /gene="brnQ"
                     /locus_tag="ACG804_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFS4833666.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         1175 a          744 c          789 g         1361 t
ORIGIN      
        1 aaattttgga atcttagttg tgtttttcag aaaactctct taatatggaa gtaattaaac
       61 ttttttagtt aggatgattt aaaaatgaat gaagagcaag aactgcagcg tggactgaaa
      121 aatagacatg tccaactgat ttctattggc ggagcgattg gaacggggtt gtttttaggt
      181 tccggaaagt ctatccagct agctggccct tcgatattgc tcgcctatct tattactgga
      241 tgcatctgtt ttttcattat gcgtgcgtta ggcgaacttc tgttatcaaa caccaataac
      301 cattcttttc tggattttgt tgcagaatat cttggcaaaa aagcggcttt catcactggc
      361 tggacgtatt ggttctgctg ggtatcgatt gcaatggccg atttaacagc catcggaatg
      421 tatgtacgct actgggcgcc tggtgttcct cagtggcttc ctgaactgat tgcattaggt
      481 cttcttcttt gcttgaatat ggtggctgtc tcattgtttg gtgagttaga gttttggttt
      541 gcattgatca aagttgtagc gatcattgcc tttatcctcg taggagctta tatgatcctc
      601 acccactata cgacagatat tggcacagcc agtatcacga atctatggtc tcatggcgga
      661 ttctttccaa ctggtgcaaa aggatttatc ttagctttcc aaatggtaac ctttgctttt
      721 gctgggatag aattagttgg attagtcgct ggagaaacag aaaatcctga aaaagtgttg
      781 ccggaagcta tcaataatat tcctatcagg atcatcttat tttacttagg atctcttttt
      841 gtcattatgg caatctatcc atggaacagc ttgaatccag ataacagtcc atttgtagaa
      901 gtattttcgg aaattgggat cacgattgct gcttccttga tcaatttagt cgtattaagt
      961 gcagcagctt ctgcctgcaa cagtgcaata tatagtacag gacgtatgct tcgttcttta
     1021 gcgcaagaag gcagtgcccc taaaaaattc aaaaagttaa caacacatca tgtgccaggg
     1081 aatgctttga cattttctac tatcgtcatt ttcatttctg ttatcttgaa ttacgtgatg
     1141 cctagtgaag tattcacact agtaagcagt attgccacta cttgtttctt gtttatctgg
     1201 agtatgcttg tctacacgca catgaaatat cgtaaaagta tcctcggcaa aaaagctcat
     1261 tcatttaaaa tgccgttgta cccatttagt aattatctgg tatttcttta catggccttt
     1321 gtgtgtgtcg tcttgttcct aggaaaagat acgagaatcg ctttattact aacacctgtg
     1381 tggttcttgc ttctattact aatctatcat atgaaatatg aacgtaagaa gtaagaaagt
     1441 agttgtgaca gaagtggtca gcttcgagaa ataagaagga atttacgaaa attgcttctt
     1501 aaatttttgt gaaatttcgg cttatttctt ggagataaaa gcttctgtcc cagcctcttt
     1561 tctatttccc cggaaacaac cgctgataat aggcatctgc ttttttatag gaaaaaatcc
     1621 aaataccaga tacaaaaaaa cgtccgaata acccgatcaa cggtacaaaa aagacaccgg
     1681 caatcaagca taagttaatc atcatggaga taagacttcg acggtccttt gacaaaactc
     1741 tcacgacatg ggaatctggt ttatttgctt tcatgatttg cctcatcaag ataccaaaag
     1801 aaaaactcca catcgtgtat actaagacat aagccatctc aggccaaaaa gcttcagggt
     1861 tacgcccgac ccaactagta acagaaggac ataaagtcag ccaaaagagc aaaaagatat
     1921 tcgaccagac cactcggtaa ttaattcgtt ctgccatctg aaatatacga tgatggttca
     1981 cccagatcac cgcaacaaat ataaagctga tggtataagc taataatgta tttcggatga
     2041 cccataaaga atgaaagcta gatgtattag ggatcttgat ctctaataca agaactctca
     2101 aaacaatggc taccactcca tcagtaaatg cttctaatct cgactttgtc acgatgattc
     2161 ctcctcagat gattcagcgc ttttatttta tcacttacgt tattaaataa ccatcgtttt
     2221 atatagggaa ttttctgaaa attgttgcat atttttcgaa attttgttac ttttaaaaaa
     2281 accgtaaagg agttatgtat gacaaaaaaa ttatcattta aagactatct ttttataggc
     2341 tccatgcttt tcggtctatt ttttggtgct ggaaatctta tctttcccgt tcatttgggt
     2401 caagaagcag gcgctgctac cttttgggcg aatctaggtt tcttggttac cggtatcggt
     2461 cttcccttct taggggtgat tgccattggt gtatcgaaaa gctcaggtgt atatgaatta
     2521 gcaaaacgga taaatcaaac atatgcgatg gtttttacca tcttgcttta cttagttatc
     2581 ggaccgtttt ttgctttacc tcgccttgca accacatctt tcgagattgg tttagcacca
     2641 tttatcgatc ctagcagaca gacgctatat ctagcaattt tcagtattgt attttttgtg
     2701 ctggcttggt ggttttcaag aaaaccgaca aagatattag attatgttgg aaagttcctg
     2761 aatcctgcat ttttggtttt attaggtgct ttgcttctcc ttgctttttt gaatccacta
     2821 ggttctgtaa atcaagcgcc tattcagcca aattatcaag agcatgcttt tttcacaggg
     2881 tttactcaag gatataacac attagatgcg cttgctgctt tagcatttgg gatcatcatt
     2941 gtcacaacaa tccaaaacat gggtgtaaca aaacctgctg aaatcgctaa agacacgatc
     3001 aaatctggtg cgatcagcat tatattgatg ggaatcattt atactttgct cgcttattta
     3061 ggtgctatga gcttaggtag ctttgctcta agtgaaaatg gcgggatcac gctggctcag
     3121 attgctgatc attatttagg tacttatggc agtatcttat tagcatttat cgttatatta
     3181 gcttgcttga agaccggtat tggtttgatt acagcttttg cagaaacatt cacagatttg
     3241 tttccgcaaa gaaattacgc attctttgtt gcacttgcta gtatccttcc ttgtttagcg
     3301 gcaaacgtag gcttgacgaa tatcattcaa ttttcgttgc ctgttttgat gttcatctat
     3361 ccattagcaa tgacactgat tttactagtg ttagttggtc ctttgtttaa gcagcgtacg
     3421 gctgtttatc gaatgactac ttattttaca ttgattgctt cgatttttga tgggttgaac
     3481 gcttgcccag aaactatcaa acaaacacct attgttcaaa atcttttata tgttgcggaa
     3541 agctacttgc cgtttttcaa attggggatg gggtggatcg taccagcagt tatcggtttt
     3601 gttatcggac tgatttggag tttcgctaag aaagaagaag tagcagattg ataaaagagg
     3661 ttgtgaaaga gacgttcagc cttgagcaat aaaaagtaat tttgaaaaat ggcttctcac
     3721 atttttgcat aaatttgact taataccgag aaactgactt ttgaacaccg tttattgaga
     3781 ggtcgtgaaa aagccgctta gtttcaagta ttaagaaata ttttgtgaaa atggcttctc
     3841 acatttttgc ataaatttga cttaataccg agaaactggc ttttgaacac cgtttattga
     3901 gcgtctataa actgacctga gtattagaga aacaaaacgg caaagtagct ccatatactt
     3961 tgccgttttg ttttgaacta ataccgaaga gaagctgatc aaacaacatt tcttttataa
     4021 tatagatttt agacatatat atgatataaa aatagttttc gcaaaaaaa
//
LOCUS       DAZUJR010000148         4032 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.153, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000148 DAZUJR010000000
VERSION     DAZUJR010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4032
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.153"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(141..1646)
                     /locus_tag="ACG804_002803"
     CDS             complement(141..1646)
                     /locus_tag="ACG804_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFS4833667.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(1643..2329)
                     /locus_tag="ACG804_002804"
     CDS             complement(1643..2329)
                     /locus_tag="ACG804_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFS4833668.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2522..3943)
                     /gene="gndA"
                     /locus_tag="ACG804_002805"
     CDS             complement(2522..3943)
                     /gene="gndA"
                     /locus_tag="ACG804_002805"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HFS4833669.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1109 a          854 c          690 g         1379 t
ORIGIN      
        1 acttacattt aattaacgga tgttattcta tttaattgtt cgctagtttt tttataatga
       61 catccctgaa tttctcactt gcttgtattt tgtaccttat tctttgttgg atatataaaa
      121 aaacaagtaa agcacatgct ttacttgtct tctgcctttg cgataggaat aaagattcta
      181 aaaattgtcc cttgccctac tacactttct gctaagatac gtcctttata gttttcaacc
      241 agttgtttag cgatagacaa ccccagacca tttccaccct tcgttctagc tcttgcttta
      301 tccactcgat aaaaacgatt gaagatctta ttaaggtctt ctttgggtat tccttcgcca
      361 aagtcctgaa tcgcgatctc aaattcattc agagtggaag aaatagagat atggacttct
      421 tttcgtgtag ttgaatactt tactgcgtta tccaatatga taatgattaa ttgttcaaag
      481 tgattacgat aaatttgcag ggtcacttct tttgtcaaat catcatctaa agtgatcaca
      541 tagtctggat ataatatctt gaaattatta taaacttgat aggtgacttc ttttccttta
      601 gttgtttcat tcgcataatg aacatctact tgttctgctc ttgataagtc tagcatctct
      661 tgaactaagc ttttcatacg gctgatttct tgcatgctgg cgcttaatga ttcttctaat
      721 atctcaggat catctttccc ccaacgattt agcagactaa gatgcccttc aataattgca
      781 acaggtgtcc ttaactcatg agatacgtct tccacgaatt gctcttgttg ttcaatatac
      841 aaacgcatac ggtcaagcat ctcattgaat atttcagcta aatctgccaa ttcatcattt
      901 gtgtcgattt caggcatgtg gatatctgat tgcggatctt tacgtatagt atccattgta
      961 tctctgagta ccttgagtgg ttttaagaaa taagaagata aaaagaaacc taaaatacta
     1021 cttaagatca aagaaacaac ttctaaaaca ataagagtca ataatagctt atttcgaata
     1081 tcatagaaag aagataattc atagaagctt tgcgcatagc cgatcttttc tcttgtacct
     1141 ttagaatata taggctggat agataaaaag ccagtttttc cttctagtgt aacgatcgtt
     1201 ggaactttac gtgtagtctg aatcaggttt cgactgtttt catgggtttt aaaaatcaag
     1261 ttctcgtcca aatcataaac ataaagatcc attgatggct gccctagctc agctataaag
     1321 gaatcgatct tcattaagtt tccttcgacc agtgaagtat gatctacgac ctcatctccg
     1381 tcatttgtcg ctttcgtcag attacgatac gtatttacta atgtcagttc ttcatccgag
     1441 ttagccaaac gagaagctac ttctgaaatc gtacgctcta cattgtttct ttcttttgcc
     1501 acaatcagat tgatagatga tttataggta atgacagcga aaattgtaaa cacaacgaat
     1561 atgaagaaag aactcgcaaa ggcccacttg attgtcaagg agggcccttt cagttctctt
     1621 ttttccgatt ttttcggctt tatcacgagc gcatcacata acctgttccg cgtacagttt
     1681 ggatatagct ttcctccccg ggaacgtcaa ttttgttgcg aagataacga atatatacgt
     1741 ccactacgtt tgtttcaact tctgtttcgt atccccacac tttatttagt aaaacgtcac
     1801 gtgctaatac cacgttcacg ttttccatta aagtaagcag caactcgtat tctctttttg
     1861 ttagttcaat tacttcattt ccgcgacgta cgacacggtt ttctttttcg atagtcaaat
     1921 cgcgataagt aatagtagtt tgtttagcca catttttatc gccttcaata tcgattcgac
     1981 gcaacaatgc acgaagacgt gctaataatt cttcgatagc aaatggtttg acgatgtagt
     2041 catctgctcc gtggtcaagt ccagatacac gatcgatcac agaatctctt gcagtcatca
     2101 taatgattgg tgtatttttg acttggcgta cacgtctgca gacttctaaa ccgttcaatt
     2161 ctgggagcat cagatccaac aatatggcat cccactcatt atttaatgcc gcatctaaac
     2221 cagttcggcc gttgtagtgg acttctgcgt tatacccttc atgcttcaac tctagctcga
     2281 caaatcgtgc caagttcttt tcatcttcaa tgattagaat attgctcatt tattatttta
     2341 tcctttctat tctactggct ttttaaaaac tctatcatta taccgataat atgcttaaaa
     2401 atctatagtc attttatcat ggatagcaat tttaaaaaag agctgaagtc tactcataac
     2461 aatcgacttc agctctttcg tcctcttttt attttctcat ttcctaacag ccgaaagact
     2521 attattcttc atggtaccat gagtaatgga agattccttc tttgtcgaca cgctcatagg
     2581 tatgtgcgcc aaagtaatcg cgttgggctt ggattatatt tgcaggcaga cgttctgctc
     2641 tgtatgaatc gaagtaagcg atggctgatg agaaagtcgg tacaggtacg ccagcttgga
     2701 cagccaaggc aacgacgtct ctgactgatt gctgatattt tttcgtgatt tcaacgaagt
     2761 aatcatctag caataaattt tcgatctcag gatttttgtc ataggcatcc gtaatttttt
     2821 gcaagaatcg agctcggatg atacatccag cgcgccagat ttttgcgatt tcaccaaatg
     2881 gcaagtccca atcaaattct tttgaagcga cacgtaattg agcaaatcct tgggcataac
     2941 tcatgatttt actgaaatac aacgcttctc ggattttttc gaccaattct tttttgtctc
     3001 ccgtgaactc aaaatcgttc gtacgagaca aaatcttgct tgcttgtacg cgttcttctt
     3061 tataagcaga aatatagcgg gcaaatacag attcagtgat caatggaagt ggcacaccta
     3121 agtcaagcgc gctttggctt gtccatttac ctgttccttt attcccagct gcatcaagga
     3181 tcacatctac tactggttta cctgttcctt catcgtcttt acgtgtcaga atgtcagcag
     3241 tgatttctat caaatagctg tctaattcgc cttgattcca ttctttaaag atatcagcca
     3301 tttcttctac tgaaaggttt aaaatattct tcattaagtc ataagattca gcaatcagtt
     3361 gcatatctcc atactcaata ccgttgtgta ccattttcac ataatgtccg gctccatttg
     3421 ggccaatata tgtgacacat ggtgctccgt cttctgcttt tgcagaaatt tgctctaaga
     3481 ttggtgcaac tagcgcatag gcttcttttt gtccaccagg catgattgaa ggtcctttta
     3541 aagctccttc ttcaccaccg gaaacgcctg taccgataaa gttgatgcca gagttggcta
     3601 actcttcatt acgacgcatc gtatctttaa agaatgtatt tcctccgtca atcaaaatat
     3661 cgcctttatc aaggtgagga agtaactctt ggattgttgc atctgttgcc ggtcctgctt
     3721 tgaccattag caagatccga cgtggtttct cgatagattc tacaaattct tcgattgtat
     3781 atgttgcttt gaaattttta tctgggtgtt cttctactac agcggttgtt ttagcccctg
     3841 tacgattgaa taaagccact gaatagccgc ggctttctat gttcaaggct agatttttac
     3901 ccataacggc cataccgaca acgccgattt gttgttttga catatgaact cctcctacat
     3961 acgggatttc tccctaatct cttacattat agcttaacac ggctacattg caaactaaag
     4021 aacaacatat tt
//
LOCUS       DAZUJR010000149         4014 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.154, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000149 DAZUJR010000000
VERSION     DAZUJR010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4014
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.154"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(175..1461)
                     /locus_tag="ACG804_002806"
     CDS             complement(175..1461)
                     /locus_tag="ACG804_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFS4833670.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(1454..2722)
                     /locus_tag="ACG804_002807"
     CDS             complement(1454..2722)
                     /locus_tag="ACG804_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFS4833671.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            2974..3435
                     /gene="mscL"
                     /locus_tag="ACG804_002808"
     CDS             2974..3435
                     /gene="mscL"
                     /locus_tag="ACG804_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HFS4833672.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(3494..3940)
                     /locus_tag="ACG804_002809"
     CDS             complement(3494..3940)
                     /locus_tag="ACG804_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4833673.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
BASE COUNT         1136 a          816 c          707 g         1355 t
ORIGIN      
        1 gattacttcg tttgatttta ttttaatata agttgattaa aagagagcat gatttgtttt
       61 attttctcac taatttttcc aacacaacta agaataccat aaaagctgat tttggaggag
      121 gttcctacta caagtctaaa acgaaattta agacttttcc tcataaatac tggtttattt
      181 tggtctcatg taaaactcgc tgaaggcctc ttcacttata aatgcttccc cagctgccag
      241 tacgtctttc atttggatcg aatcgatgat ttcaggaaga tcaaataaag ttcgatcgcc
      301 aaataaactt tgcgtaaatt gattggcaat atattcgatc gaatttaatg attggaaata
      361 ttgtccaagc attttcttct tcagcaaatc gagatttgtt tctgacactt ccggatcatc
      421 agcgaatcca agaatgattt ctttgacttt ttctgctgct ttctctggtt cgtccgtatc
      481 tccgctgaag tccgcaaagt gaaattcacg atccaagctg aattcaaaac caaagctgtc
      541 atcgataatt ccttgattgt acatcgctag atagtttcga gaagtattgc ctaaaatcat
      601 ttggaacaac agattgattg ctgttttata gcgtaacagt tctgttcctt cttgcggcaa
      661 tgtgtctaat cctttaatac caagtacaaa tttatctcgt gtaatggctg cttccaatgc
      721 actttgtttg atgatttctt ttgtgttttc agggaaataa cgtacaattt cttgctttgg
      781 agggaaattt tttgcttctt ggttttcccg aataagtttc atcaatttct caggctccat
      841 cttaccaact acaaataaaa ccatattgct tggctgataa aacgtccgat agcacgtata
      901 caagtcttga gctgtgattt tgtcgatact ttcaaccgtg cccgcaatat cgatatgcaa
      961 tgggtgtgta ggatacaagt tatttagtat gccaaaaaac atccgccagt tagggtcgtc
     1021 ttcatacatt tggatttcct gaccgatgat tcctttttcc ttgtttacag tttcttctgt
     1081 gaagtaaggt gcttgtacaa aatcgatcag agtcgtcaga ttcttttcta cctgatccgt
     1141 cgtagaaaac agatagctgg ttttcgtaaa acttgtgaaa gcattggcgg aagctccttg
     1201 tttcccaaat aattgaaaga catcaccatc ttctttttca aacaacttat gttctaaaaa
     1261 atgggcaatt ccatctggaa ctttcacctt ttctttttca ccatagggaa taaattcgtt
     1321 atcgatcgaa ccataattcg tactgaacaa accatatgtc ttgtgatagt catttttagg
     1381 caacaaatac acggtcaaac cgtttggcag tacttcatga taaagtgttt cattgatttg
     1441 ctcatattct gttttattca tttgcatttc ctcctgctaa aaagaagatt gcctgcaatt
     1501 cgatttgctc agctacttgt tgtatctctt tgatcgttac gctctccata cgtttcaacc
     1561 attcttcatc agataatttt gtttccggca gccagctgtc caaaaaagaa gcttcgattg
     1621 ccgcttgcgg agagtctaga gaaagcagat attggtttct cagcattgct tttgtctgag
     1681 acagttccaa ctctgttatt tcaccatttc gcaaactttc taattgctcg tgaatcagat
     1741 gaagtacttg atttcggttc ttttcatcga taccggtttg gacactcatg aatcctcgga
     1801 acgtatccac gctactagag gcataataag ctagactttc tttctctctg acattcatga
     1861 aaagtttaga gtgaggaaaa ccgccaaata aaccgttaaa gaccattagc gcaaaacgtt
     1921 ctggttcatc gtaatacaca tttgtctgat aagctaggtt cagctttgct tgaacgattg
     1981 gctcacgtac ttgtcgttcc ttcacgatat tcacttgagg ttgggtataa aacagatctg
     2041 gataaactgt ttcccgcgac tcaaatggta attgcccaac tgcttcagct gctttgtccg
     2101 gatcaacatc gccgacaaca aaaatgtcga tttgatcatt tgccatcatt tcttgatagt
     2161 aggacgctag cgaactagca gtgatcttgt ccaaatcttc gactacgccc aaccctggga
     2221 tcttttgttc cgggctgttt tcaaaataaa gttcttgcaa ggcataggaa gcaaaagttt
     2281 gtttatcttc cttcaaactt tccaaatata gacgcagatt gttcttttcc aagtcaaacg
     2341 tcaactgatc aaactgatga tttttaatat ttggataaaa taaaacctct tttaaaaaat
     2401 ctaccgcttg agaaaaaagg tttggatcat tgacatattc accattcaca aaactgatcc
     2461 ctgcgtttag ccaatgtaaa tttccttttt ttctaactga taatccaaag cttgcgccat
     2521 aaagctctgc aagttgcgca cttaactttg tctgatccgg ataattcaaa ctatttgttt
     2581 ccaacatgct gctgagaagt gaacgtttcg tgatgacttc ttgttgcaga cgcgcagtaa
     2641 aacggataaa aatccggatc gttttgtatt gttttgttgg taagacatga agattcacgc
     2701 cttctgccaa ttgatacacc atatttatat gctccttttc acagttgatt gcccgcttac
     2761 tcttttaatg ggtcaacctg ccttttttac ttattcctct gcttgaaatt tataagttca
     2821 ggcaattcgc cgttttttct aaatgatgtt acactttata gtatagcata gatgtttttt
     2881 atcaaaagaa acagacggct aaaagcgtat attgtttttt tattttttat ttttcgatat
     2941 actaaagaca aataaaagaa gggagggtca ttcatgatca aagaattcaa agagttcatc
     3001 atgcgtggag atgtcttgga tcttgctgtc ggcgttgtta ttggtagtgc gtttacaagc
     3061 atcgtaaacc aagtggtgca aggcttgatc acaccactaa taggttggtt tgtcgcaatg
     3121 atcacaggta cttctgattt agaaggagca ctttcaattc ttgactggtc gccgacaaaa
     3181 ggcgtcacat ttgcgtttgg taacgttatt agtgctatca ttacatttct gatcactggt
     3241 tttgtcttat tcttagttgt caaagcggca aaccgtgcga agaatttacg ctccaaagaa
     3301 gagcaagtgg aagtggaaga aactcctact gcagaagatt atcttagtga catacgcgat
     3361 cttcttgcca aacaagtggc agaagacaat acacatccag tagagcaaac aaatctttcc
     3421 gatacttcta aataataaag aatctaaaaa aaagaaagcc gattttcagt gtcggctttc
     3481 tttttttaga ttcttaactt gctacttgtt cctttttcat gtcgatatgt ggaatatcat
     3541 cttccaaata cacatctgag attgccttga atccaaacga ctcataaaaa gcttgtaggt
     3601 attcttgtgc gccgatcacg attggttttt ctggaaaatt tttctggatc atgttaatcg
     3661 tttcttgaac aatctttctt cctaaaccat ctttacggtt gtcctgatga acaaggacac
     3721 gtccaaaatg gatactctcc gcttcttcat atactcgcgt gtaggcaagg atcttcccat
     3781 cagtatcttg aaaaaacgta tgccaagctt gtccatcaat gtcatcaact tcttgataag
     3841 gacactgttg ttccacaaca aaaactgcga ttcgttcttt gacgatcgcg taaaactctg
     3901 ctgttgacaa ttcttcaaat ttctttacct gatattccac taagcaaacg ccccctgctt
     3961 ttttattctt agcataccga ttcgcacaca aaaaagcaaa cgaaccttac gaat
//
LOCUS       DAZUJR010000150         3992 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.155, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000150 DAZUJR010000000
VERSION     DAZUJR010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3992
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.155"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            272..580
                     /locus_tag="ACG804_002810"
     CDS             272..580
                     /locus_tag="ACG804_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HFS4833674.1"
                     /translation="MFQNKGQRYVTKGVMDSLLVELQTLCWNLIDQNVQKKLPLDYLQ
                     IFEFSIEKGNQKLVHRQEEPEARKEYLISPKLRLESVSQKIWVIDSGEYQTMLLPEEY
                     "
     gene            607..906
                     /locus_tag="ACG804_002811"
     CDS             607..906
                     /locus_tag="ACG804_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HFS4833675.1"
                     /translation="MLETAIEVLEKCAQLVTTPEEWGYESVTMEKEEIEMGTLPKNVH
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVCGLLVEGRLVWSQIGGTNE"
     gene            1080..1625
                     /locus_tag="ACG804_002812"
     CDS             1080..1625
                     /locus_tag="ACG804_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HFS4833676.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEEKEKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFSRGNDEQSLE
                     ILTTIFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLSDHSLLFQ"
     gene            1781..2077
                     /locus_tag="ACG804_002813"
     CDS             1781..2077
                     /locus_tag="ACG804_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833677.1"
                     /translation="MKVDGECLTSSYKSIYEFFEEKGLDTDLLYQFYIAFRGQQLSFP
                     MKMYDRELVAQKIETMIQENHSIDSRKLTDRYGFSTRWIQSIIRQQQKEQHVHG"
     gene            2070..2960
                     /locus_tag="ACG804_002814"
     CDS             2070..2960
                     /locus_tag="ACG804_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EcsC family protein"
                     /protein_id="HFS4833678.1"
                     /translation="MANEETVGLRIIEEAFKLPMVKVDRRAFLIQTFQGNVSDIEGLI
                     EKGPQAFLSKEMLDREAQKCIQSITLKSSAVSLATGLPGGIAMAATIPADLLQFFGYS
                     LRLAQEISYIYGFKDLMGETGEFSEEAKNTLILYLGIMLGVTSAGSAVRAMSGKLSTQ
                     ALKKIPQKALTQTLYYPVIKRVLGIFGTKLTKNTFAKGISKAVPVVGGVVSGGINYLS
                     MKPMATKLQTELGKNVAYTEKNLQQDLDILEGEFEEVSSDIVSSDTVLSQLERLSHLL
                     ETNMITEEEFQQLKQELLKK"
     gene            3042..>3992
                     /locus_tag="ACG804_002815"
     CDS             3042..>3992
                     /locus_tag="ACG804_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HFS4833679.1"
                     /translation="MKAKRLFLLGTILLLGGCSTVSQNEQKKQVDSTTYETETTRKES
                     STKEIETTTQETKTTESSSKATSSDTSDFQIKQELWDTNKASQLATFVPQWGKTLGQE
                     YKSYNPQNNVSLYGTPLPSAVIDGNWKMAINEAPVTVQWSEDGTGNAGFNLVAVYSDV
                     ETGEYLGQHVYFFGFQNGQPKVYLTQQNQGNENNYLYFNETQNQQLKQGFTDIINGQT
                     PQTPVVEESTQQATTTTTQSTSSSGISNWEAAKETVLNNKALWIYESPDKNEANTNII
                     ESTQYRKDLMQDENGEFYPVDISTDDIGNTVMNGGKQFRVY"
BASE COUNT         1482 a          577 c          776 g         1157 t
ORIGIN      
        1 tagttcatta agcaaaatta agtatcttag ttactaataa ctatataaat tttaaacttg
       61 tagtcgcaat ttagtataga ggtactaaat atgaaaactc catactttta gaaaagcatt
      121 tcttatattt agttgtgatg tctattcagt taattgaaat aaataatata gcaatgaaat
      181 agagataaat tcaaatatat attatatcca tgaagtccaa tcttctttat agaagattgg
      241 gctatttttt acgacaaagg agggaaaaga aatgtttcaa aataaaggac aacgttatgt
      301 cacaaaggga gtaatggaca gtttactggt ggaattacaa actttatgtt ggaatttaat
      361 cgatcaaaac gttcaaaaga agcttccttt agactatctt caaatctttg aattttcgat
      421 agaaaaagga aatcaaaagt tggttcatcg tcaagaagaa ccggaagcaa gaaaagagta
      481 tctgatttca cctaagcttc gtttggaatc agtgtctcaa aaaatatggg tcattgattc
      541 gggtgagtat caaacgatgt tattaccaga agaatactga tatctaaaag aaaggagcga
      601 aatgacttgt tagaaacggc tatcgaagta ctggaaaagt gtgcacagct agtcactact
      661 cctgaagagt ggggctatga atccgttacg atggaaaaag aggaaattga aatgggtacg
      721 cttcctaaaa atgttcatct accacgttta gtgatgacac atctttatat ttattgcgca
      781 ccagaagatg gaaaagacta tgtagtttat ttcattacag atattaccag ccagcgagaa
      841 tttgtttgtg ggttactggt agaaggacga ttggtttgga gtcagattgg aggaacgaat
      901 gaataagatc gattatttga gaatgattgc gaaatgttta gaagatatcc ttaccgcgat
      961 ttatcgaatt ctgaagaaaa aaggagaaag aatatgaaat attttcaact agtattgaca
     1021 cttataacgg caatggtaat tgaattgctt gaacaaaaat tagcatagga gaaaaagaga
     1081 tgattgaaaa agaattagtg accacacaaa cagaagtttg gcgagatcct catcataccc
     1141 atcgctatgt tttcaaacga caatgggcaa tcaaaggaaa agaagagaaa gaaaaattag
     1201 cagtagtcat taccattcgt ccaacagata cagaaccatt tacgaatgat ttgagtatgt
     1261 tattaatcga aaagaatatc cgacaattgg gatttactgg ttttattgcc gtgaatcttt
     1321 tttcgtatac aaaagcgaaa agtcctcggg tattttctcg tggcaatgat gaacaatctt
     1381 tggaaatatt aacgaccatt tttacagaaa agaaaatcaa cactattatt tttgcttgtg
     1441 gttcgattac ggcaacgagt caagtggctt atgaacaagc aaagaccatt tacgatcaat
     1501 tgagtgcgaa acaaaagaag atgaccaaag tattgataaa tgcagaaggc aagttatctc
     1561 acccattaag tattcatgtt cgtaatgaat ggcaattgtc ggatcattct ttgttatttc
     1621 aataaacgaa aataagtatt caatgtatat gtttcttttt ctgttatttt acttgttctt
     1681 ttgcagacta aacaacttgt aaaacctctt gttatatgca ttatcaatga aggaatcaat
     1741 atgatatttt taaaatgtca ggggaaatgg aggtgagcaa gtgaaagtag atggggaatg
     1801 tttgacgagt tcgtataaaa gtatctatga attttttgag gaaaaaggac tagacacgga
     1861 tttactttat cagttttata tcgcttttcg tgggcaacag ttgtcgtttc caatgaaaat
     1921 gtatgaccga gaattagtcg ctcaaaaaat tgaaacaatg atacaagaaa accattccat
     1981 tgattctagg aaattaacgg atcggtatgg tttttcaacg agatggattc aaagtattat
     2041 cagacaacaa caaaaggagc aacatgtaca tggctaatga agaaacagta ggtttgagaa
     2101 tcatagaaga agcattcaaa ttaccaatgg tcaaagttga tcgtcgagca tttttgattc
     2161 aaacatttca agggaatgtt tctgatattg aaggactcat agaaaagggt ccacaagcat
     2221 ttttatccaa agaaatgcta gatcgtgaag cacaaaaatg tattcaatcg attaccttga
     2281 aatcaagtgc ggtatcgtta gcaactggac tgccaggagg tatcgctatg gcagcaacta
     2341 ttccagcgga tctccttcag ttctttggtt attcattacg attagcacag gaaatttcgt
     2401 atatttatgg atttaaggat ttaatgggag agactggaga gttcagtgaa gaagcaaaga
     2461 atacgctgat attgtatttg ggaattatgc ttggagtaac ttctgcaggt tctgccgtac
     2521 gagcgatgtc tggaaagctg tctacacaag cattgaaaaa gattcctcaa aaagcattga
     2581 cacaaacgct gtattatcca gtaatcaaac gagtactagg tatttttggt acaaagttaa
     2641 ctaaaaatac ctttgcgaaa ggtatttcta aagcagtacc agttgtggga ggcgttgttt
     2701 caggaggcat caattacttg tctatgaaac caatggcaac gaagcttcaa acagagttag
     2761 ggaaaaatgt agcgtataca gaaaaaaatc tccaacaaga tttagatatt ttagaaggtg
     2821 aatttgaaga agtatcttct gatatcgtgt cttctgatac agttctttct caattagaaa
     2881 gactttctca cttgttggaa acgaatatga ttacagaaga agagtttcaa caattgaagc
     2941 aagagctgtt aaagaaataa ttatttagaa aaagcaacca cttatacggg tggttctttt
     3001 tcttgaatga attcaaattt attattagga gaagaaaaag gatgaaagca aaacgattat
     3061 tcctattagg cacgattctt ttacttggag gatgttctac tgtctctcaa aatgaacaaa
     3121 agaaacaagt ggattcaaca acttatgaaa ctgaaacaac aagaaaggaa tcttctacaa
     3181 aagaaataga aacaactact caagaaacta aaacaacaga gtcttctagt aaggcaacga
     3241 gttcagatac gagtgatttt caaataaaac aagaattatg ggatacaaat aaagcatctc
     3301 aattagcaac ttttgtccca caatggggaa agacattagg tcaagaatat aaaagctaca
     3361 atcctcagaa caatgtaagt ctgtatggta cgcctttacc aagtgcagtt attgatggaa
     3421 attggaaaat ggcaatcaat gaagcaccag ttactgtaca atggtcagaa gatggaactg
     3481 gaaatgcagg atttaattta gtagcagttt attctgatgt agaaactgga gaatatttag
     3541 ggcagcatgt ttactttttc ggttttcaaa atggacaacc taaagtttat ttaacgcaac
     3601 aaaatcaagg taatgaaaat aattatctgt actttaacga aactcaaaat caacagctaa
     3661 aacaaggatt tacagatatc attaatggac aaactcccca aacaccagta gtagaagaat
     3721 ctactcaaca agcaacaact acaacgacac aatctacaag tagttcagga atttcaaatt
     3781 gggaagctgc taaagaaact gtactaaata ataaagcgtt atggatttat gagtctccag
     3841 ataaaaatga agcaaatact aatattattg aatccaccca atatagaaaa gatttaatgc
     3901 aagatgaaaa tggagaattt tatccagttg atatttctac tgatgatatt ggaaatacgg
     3961 taatgaatgg aggaaaacaa ttccgtgttt at
//
LOCUS       DAZUJR010000151         3901 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.156, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000151 DAZUJR010000000
VERSION     DAZUJR010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3901
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.156"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..398
                     /locus_tag="ACG804_002816"
     CDS             <1..398
                     /locus_tag="ACG804_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833680.1"
                     /translation="FCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTF
                     LWLLFTRIYIFLMSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTY
                     FIGILEGIIFYIGYFPNKNNNFYFYRNKL"
     gene            complement(524..1201)
                     /gene="nth"
                     /locus_tag="ACG804_002817"
     CDS             complement(524..1201)
                     /gene="nth"
                     /locus_tag="ACG804_002817"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HFS4833681.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(1208..1906)
                     /locus_tag="ACG804_002818"
     CDS             complement(1208..1906)
                     /locus_tag="ACG804_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFS4833682.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2174..3358
                     /locus_tag="ACG804_002819"
     CDS             2174..3358
                     /locus_tag="ACG804_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HFS4833683.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            complement(3364..3807)
                     /locus_tag="ACG804_002820"
     CDS             complement(3364..3807)
                     /locus_tag="ACG804_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFS4833684.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
BASE COUNT         1013 a          767 c          638 g         1483 t
ORIGIN      
        1 aattttgttt attattaaat aaatttactt taattgctcc tatccttgca tttattattt
       61 tttctgtact tttaagcact actcttaaag gaaaatttat ggaaagaagc tctcatgcaa
      121 tgattctcac ttttttatgg ttgttgttca ccagaatcta tatttttctg atgagcctga
      181 aaccgcccaa atccattagt ttatgtttag ttataaatgg tattttttta ttatcactta
      241 tcatttttat tacaccttta gatagatacg tcacttattt atataatcct ttggaatact
      301 ggacttattt tataggtata ttggaaggca ttattttcta catcgggtat tttcccaata
      361 aaaataacaa cttttatttt tatcgcaata aattgtaata agttaccatc ctagctactg
      421 agtatgtaca tttacttttt catgcaaaaa agataaacga aacagctttt ctccataata
      481 acaagataat tcatacattt atttgcaatt aaagaaacca cgtctacagg cgtggtttct
      541 tttttagcgc cttttctttt agacgcatcc gatttttccc atcttgacat attgatagca
      601 aaggacatac ctcgcacttg ggatttcttg ccgtgcaatg atatctacca aaaaaaatca
      661 gtgtatgatg tgtctttacc cataattctt gtggtacttt ccgcatcagt gtttcttcta
      721 cttccatgac cgtagcatct agtttgcaga tcctcaggcg ttttgagaca cgttccacgt
      781 gggtatctac tgcgattgct ggtatcccga atgcatcccc caatacgaca tttgctgtct
      841 ttctgcctac accaggaaga gacatcaatt cttctcttga cgttggcact tgcccatcga
      901 aacgttcaat cagctgctgt gcacacgctt tgatgttttt tgctttattt cgatacaaac
      961 caatcgtttt tattttaaga atgatttcat cgattgaagc ttctgctaac gcatcgggtg
     1021 tcggaaaaga ggcaaacaaa tctggcgttg ctttattcac tgatacatct gtcgcctggg
     1081 cacttaagat cactgcaatc aataactcaa atggattatt gtgcttgagt tctccatgtg
     1141 cttcgggaaa cattccatac atcgtttcta gagcttccat tgttttttgt ttgcttaaca
     1201 tattccgcta ctcctccaac caatttttca gtgagacttt cggcaattct tcttgttgag
     1261 ctgactgttc tacttctctt tgaagaagct gctgttttct tcgtttttgg tcttcttcca
     1321 cttgttgttt tgtacgtaga ttttttcttt cccacgatag caaaatgcgg tcaacgtaat
     1381 taaaactata agcctgattt aatacggctt cccgcagtgc tagcttcaaa atttccggct
     1441 gataatggtc ttcttctagc cattgtccga tccgctggaa ctcgatcgaa gaaagcgggc
     1501 gtccaaattc ttgttcaaat aattgataca ctgactggat ttctttttct tgtgtttttt
     1561 cttcgtattt tttttcttgt gtttttaaat actcacctaa tagatcatag atggggtaaa
     1621 gattatatcg atctgctttt ttaccgttga caatcgtcgt ttctatcttg ataaatccat
     1681 ttgttacgag acgatccagt atttgaaaaa tctgatcttg tttgattccc atatccatag
     1741 caatcatctg caaatcaggg aaagtatctc cttcaagctg tgccatatgc aactgtagaa
     1801 caaataaaaa ttcttcagat tgtagaccga tcctatgata atttttaagt aaaagattag
     1861 atatgactgt ttgtccagcg cttaagtaat tttctaaatt caacatgatt tctcctccgc
     1921 tcaatcacag tatacgtaaa aaaaacatgg gaagcaagaa caggtttctt ttctatttac
     1981 ttcactgatc ggtcagattt acaatgtcgt ctacttgatt tttgtttgtt catgtttttg
     2041 atgcgtatct tcacttttcg gaataaataa attaagtaga tttcgctgtt ccttagaatg
     2101 ttgacaagga aacaaaatta ctatacacta tttttgtttc caagttaaca ttattgcata
     2161 aaggagtttt tacatgtaca gtttcacaaa taaacattct aaagtttttg gatacgtctc
     2221 tgtcttattc actggattag gatttactat cgtcagtcct gtacttccgt ttttaacgct
     2281 gccttattct cactccatac atcagcaagc tttctatatc actttgctca tgtctgttta
     2341 tgctctagct gccttcttat ctgcccccat tctcggtagc ttaagtgatc attttgggcg
     2401 tcatccgatc cttattatca gtttattagg atcaagtatc ggatatttgc tttttggttt
     2461 aggaaattcg atatggatgt tgttccttgg tcgtatcatt gaaggattga cggcaggaga
     2521 aatctccacc ttatatgctt actttgccga catcacggaa cctaatgaaa gaaccaaagt
     2581 ttttggatgg atgggtgctt tagtcggtat aggaacaacg ctgggtccta ttataggggg
     2641 tctattagct gagttgggga attctgttcc tatatttatt ggagcactct ttactttctt
     2701 aaatgccgtt tatggctaca catttatgct agaaagcctt ccaataaaaa aacgttcagt
     2761 agatttaagt ttctcccatg taagaccttt tcaccaatta caacaattat tcaagatttc
     2821 atccgttatt cctttattga cagcaggttt tgctgtttgg ttggcagctg gctctcttca
     2881 atctatcttt tctcaatttt cgattgacgc ctttcagtgg aaggctgggt tggttggttt
     2941 aagcttctct ttgattggaa tcttggatac tgtctcgcaa ttgttcatta tgcctcgatt
     3001 gctcaaaaaa ttttcagaac agcagatcac aagaataggg atgttcagtg aaatcctcgc
     3061 ctatctattc atcacattat ctggaattct tctactgccg attttgtttt tatttgggat
     3121 tatctgttat ggtttcggtg attctatttt tactcctgta ttcaatggcc aactatccaa
     3181 ttctgtctca gataaccagc aaggtcttgt aatgggcggt acccaaagta tacaatctct
     3241 atcgcgcgtc atcggcccgc taatcgcagg acagctttat gctgcagcac catttcttcc
     3301 gacggtattc ggatttttgc ttatgatttt tgcctattat cactacaata aaaaatagta
     3361 gcttcatttg ctacttcgta taaattctct gtatcgaccg ataaaacgaa atactgtgtc
     3421 aaattcttct tttgacatat tttcaaatac agtagcatct cgctgtaccc atttttgatg
     3481 gagttgctcg tgtctattcc ttattttttg tccgattggc gtcaattgaa aatagatttc
     3541 ttttttattc tcttcgcttt gataagtgtt tatgatccct ctagctatca gtttttttgt
     3601 tagcttactg atggctcctc tagtcatgta actagcattc gctaattttg tcacgttagg
     3661 atcagggatt ttcccgatat gttcaatcac ttctagttca tttagagtaa atcctgcaaa
     3721 ttctttttcc atttctggtt tattacgatg aataatctca ttagctaaat ccagatattc
     3781 ttctattagc agttgtcttt tatccatttc tacaccttct ttttctttca ttatattgtt
     3841 tttttgtttc ctattcaaca aagataaaaa tattttgtag gaaaacccaa tctgaaacca
     3901 a
//
LOCUS       DAZUJR010000152         3850 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.157, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000152 DAZUJR010000000
VERSION     DAZUJR010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3850
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.157"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(1..1155)
                     /locus_tag="ACG804_002821"
     CDS             complement(1..1155)
                     /locus_tag="ACG804_002821"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HFS4833685.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYSLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            1340..3781
                     /locus_tag="ACG804_002822"
     CDS             1340..3781
                     /locus_tag="ACG804_002822"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HFS4833686.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
BASE COUNT         1231 a          721 c          840 g         1058 t
ORIGIN      
        1 ttatattttg tagtaacgaa tatcattttc gatctttgta atcgaaaaag gtacatctga
       61 agtatattct gcacattctc cgtgttcagg aagcgtctca ctgaaaatcg tttcatattc
      121 gtcaacagtg atccgtgttc gagaatctag catctcttga tgagattgtg cgaagagata
      181 ttcttgatag ttttcttcca gataacctgt aaaaaattca cttactgcac cagaaccgta
      241 gctgaataga ccgatgcgat ctcctggctg tagtgatttc gaattttcca gtagagaagt
      301 tagccccagg tataatgaac cagtgtaaag attaccgatt cgtcggctgt aacggatgct
      361 ttcttcatag cgagccataa gacgttcctg attttcttcg tctgtttggt ctaatacgct
      421 ttgcaatgcc ttttttccca tcttagtata cggaatatgg aaagcaatcg cctgataatc
      481 ttcgagtcct cgacccgaca attctttatg tcgattccaa actttttgga atgattcgat
      541 atacgtagaa ttagataaag gaccatcaac aacaggaaat tcgctataat ctggacgcca
      601 gaaatcatag atatcttctg tcagaaatac gctgtcgtct tcaatcgata aaatacgcgg
      661 gttttgagtg atcatcatcg caacagcacc gacaccttgc gtcacttcac caccgcttgc
      721 caagctgtaa cgagcaatat cacttgctat gactagtact tttcgttctg gatgattttt
      781 gacatattct ttcgccatgt gcaaagctgc ggtgccaccg tagcaagcct cttttacttc
      841 aaaagaacga gcaaaagatt ggattttcag taaatggtgg ataattaccg cactcgcttt
      901 tgaatgatca atcccggatt ctgttccgac gatgaccatg tcgattagct cacggtcttt
      961 ttctgttacg attttgctgg cagcatttgc tcctagtgta atgatgtctt catttgcacg
     1021 attgactgcc atttggtctt gaccaatccc tatatggtat tttgcaggat catccccacg
     1081 gctttctgcc aactctgtca tatctaaata taaattagga ataaaaaagg aaagacgatc
     1141 aatccctatt ttcatttcaa cacctcttta cttatgataa aaaacttact ttactaaggt
     1201 atcataaaaa gattaaaaga aatataaaaa agagaatatt taaggattgt taaaatttaa
     1261 tcttagaaaa aaataactgg aacaagagct atttgttttt acagcaaaga atggtatatt
     1321 tttgtaggag gtggcttact tgaaagaagt cgttatgata gatgctgcaa gaacgccgat
     1381 aggaaagtat cgcggaagtt taagtccatt tactgcagtt gaattaggca cacttgtgac
     1441 taaaggatta ttagataaaa caaaactgaa aaaagataaa atcgatcaag taatatttgg
     1501 aaatgtcctg caagctggta atggtcaaaa tgttgccaga cagattgctt tgaacagcgg
     1561 tctccctgta gatgtcccag caatgacgat caatgaagtt tgcggatctg gtatgaaagc
     1621 agtgatctta gcacgccagc tgatccaatt aggtgaagca gaacttgtga tagccggcgg
     1681 aacagagagt atgtctcaag cacctatgct gaaacagtat cagtcagaaa caaatgaata
     1741 tggtgaacca atttccagta tggtcaacga cggattgact gacgcatttt caaatgcaca
     1801 tatgggatta accgcagaga atgttgcaac acaattttct gtgagcagag aagagcagga
     1861 tcgctatgcc ttgtcgtccc agttgaaagc agcacatgct gtcgaagccg gtgtattttc
     1921 tgaggagatc atcccagtca agatttctga tgaagacgtg ttatctgagg atgaagcagt
     1981 tcgtggaaat agtacattgg aaaaactggg cacgttacgt acagtattct cagaagaagg
     2041 aactgtaaca gcaggaaatg cttccccgtt gaatgacggt gcctctgtgg tgatccttgc
     2101 atccaaagaa tacgcagaaa ataataatct gccttattta gcaaccatca aagaagtagc
     2161 ggaggtcggt attgacccaa gtatcatggg aatcgctcca atcaaagcca ttcaaaaatt
     2221 gacagataga tcaggaatga atttatcaac aatcgatctt tttgagatca atgaagcatt
     2281 tgcagcttct tctatcgtag ttagccaaga actgcagtta gatgaagaaa aggtcaatat
     2341 atatggagga gcaatcgcat taggccatcc aattggtgca agcggtgcac gtatcttgac
     2401 tacattagct tacggattgc ttcgtgaaca gaagagatac ggtattgctt cattatgtat
     2461 tggtggaggt ttaggcttgg cagtcttgtt agaagcgaat atggagcaaa cacataagga
     2521 tgtgcaaaaa aaaaagtttt atcagcttac gccatctgaa cggcgcagtc aattaataga
     2581 aaaaaatgta ttgacacaag aaactgcgtt gatttttcag gaacaaacac tttctgaaga
     2641 gctctccgat cacatgatcg aaaaccaagt gagtgaagtg gaaatcccaa tggggatcgc
     2701 gcagaatttt caaatcaatg gcaagaaaaa atggattccg atggcaacag aggaaccatc
     2761 tgtcattgca gctgcaagta atggtgcaaa aatctgtgga aatatctgcg cagaaacacc
     2821 tcagcggctg atgcgagggc aaatcgttct atcaggaaaa tcggagtatc aagcagtgat
     2881 caatgcagtt aatcatcgaa aagaagagct gattctttgt gcaaatgaaa gttatccttc
     2941 aatcgtgaaa cgcgggggcg gtgttcaaga tatctctact cgggaattca tggggagttt
     3001 ccatgcatac ttatctattg attttttagt ggatgtaaaa gatgcaatgg gcgctaacat
     3061 gatcaactcg attcttgaga gtgtggcaaa caagttacgg gagtggttcc ctgaagaaga
     3121 gattctattc agtattttaa gtaattttgc tacagaatca ttggcttctg cctgttgtga
     3181 aatcccattc gaacgcttag ggagaaacaa agaaatcggt gaacaaattg ccaaaaaaat
     3241 ccaacaggca ggggaatatg cgaagcttga cccttaccgt gcagcaacgc acaacaaagg
     3301 gatcatgaat ggtatagaag ctgtagtggc agctacagga aatgatacac gtgcggttag
     3361 cgcttcgatc cacgcctacg cggcaagaaa tggattatac caaggattaa cagactggca
     3421 gatcaaaggg gataaactag ttggaaaact aacggtgcct ttggctgttg ccacagtagg
     3481 cggagcttcc aatatcctgc caaaagcaaa agcatcttta gctatgttag atattgattc
     3541 agccaaggaa ctagcacaag taattgctgc agtagggtta gctcaaaacc tggctgcttt
     3601 gcgtgcatta gttacagaag gaatccaaaa aggccacatg ggacttcaag ctcgttcatt
     3661 agcgatctca attggggcta ttggtgagga aatcgagcaa gttgcgaaaa aattacgtga
     3721 agcagaaaag atgaaccagc agacagctat acaaatattg gaaaaaatcc gggaaaaata
     3781 aaaaagcaat atctttagaa gaataaagca agatttacag ttattttatt tactgcagat
     3841 cttgcttttt
//
LOCUS       DAZUJR010000153         3807 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.158, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000153 DAZUJR010000000
VERSION     DAZUJR010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3807
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.158"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1148
                     /locus_tag="ACG804_002823"
     CDS             <1..1148
                     /locus_tag="ACG804_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HFS4833687.1"
                     /translation="NHFLTFISPTLDYHEGPMGKLPFLKVTSERKLKKIREKVDENID
                     IARKDYNALETSYEFRRNILLSYMFKKDLSEAFNCLSRQLVNQFNTLKSNEEELNDIF
                     INHYSLEKELTKEVQDEYISARLPDKAREIKDFISYSIGCIFGRYSLDEDGLIFAGGE
                     WDPSRYQKFKPDTDNVLLITDDEYFKDSQIDIVNRFIDFVEITFGKETLEENLQFIAD
                     TLGGKGTSREIIRRYFVQDFYKDHLKTYSNRPIYWQLDSGKQNGFKALMYLHRYTPDQ
                     LGKVRTEYLHELQKAYDNRIELRQQQISTSDNPKERNAMTKEIVKIQKQLKEVREYDE
                     KLGHLALKRIELDLDDGVIVNYDKLQRDPKTGEKFQIFAKGVKEPKK"
     gene            1264..3786
                     /gene="pglZ"
                     /locus_tag="ACG804_002824"
     CDS             1264..3786
                     /gene="pglZ"
                     /locus_tag="ACG804_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system phosphatase PglZ type A"
                     /protein_id="HFS4833688.1"
                     /translation="MTDINTQQIEEKLNQRFPNYGCRKIIFWFDSNQDFLEEIDSLVI
                     QNAKIYRLEKDAQFKTKRLLEYEDPETNYLIYAPFPRWDDKDEDNHLLSVLNYSEEFS
                     ADRLAIIMNELAIPLRFHQTVKQYRNFFNAKDRMRSFGEFSTHMTINKSETIELMIMA
                     VLLKSKSIRLNDLLRVVLKSFTESRENPLRELDKYQLTAKFWEFIQMKFGFTDSQPTL
                     EKLTMCLYLNYFYYQIDQEMPKKFKGFEILHLKANIITFMDQFMNDTRYMESFEQLSK
                     KVYQAIDGDGLLDSIEIDDLIEADVFSEIHAKILMFYAERLKASDTTTKIAGQTIFDS
                     LKQREKMHFASDYIYEYQLLKHAYYLVDKNRLCLPMNMDNLLTQYEKEMYWVDTHYRK
                     FIWNSDHIEEKQKYGQLYRLVEANYSKFLDQSGQIWNQTFEFKNRPSIRKFYNQAVMK
                     RSVKTVVIISDAFRYELGMNLERKLVREKKYSTNMASFLSVLPSVTEFGKAALLPNNQ
                     LTYNEGTEVLIDGKKTNGLSNRNAILQQRDANAVALNYDDVVKMNKAEVREVFNGKSV
                     IYIYHDQVDRTGDHSNENRVFEACDLAISEISRLINRLHNDGSIYRFIVTADHGFIYK
                     RSHVEEVDKIENPSRNEKDRVERRFILSEEEYEIIGTKNYSLGDSLGNDDTRNICVPI
                     TSSIFKKAGGGQSYVHGGSSIQEMLVPVLEITVAKGSNAKEPVAIELMTSNRRITGLS
                     TTLEFYQKNAISDVYDPASFWLYFEDEYGERISNEEIYVADSKTEDANQRFTKFVFEF
                     VNRRYTVEDTYYLVIKNQKNDLTERIKFIIDNPFAESFDFDI"
BASE COUNT         1382 a          535 c          716 g         1174 t
ORIGIN      
        1 ttaatcactt tttaactttt atttctccca ccttggatta ccatgaagga ccaatgggaa
       61 aactaccttt tcttaaagtt acatctgaga gaaaattaaa aaaaataaga gaaaaagtgg
      121 atgaaaatat cgatatagct agaaaagact ataatgctct tgaaacgtca tacgagttta
      181 gaagaaacat tttgttaagt tatatgttta aaaaagatct ctcagaggca tttaactgtc
      241 taagtaggca gttggttaat caatttaata ctctaaaatc gaatgaagag gaactgaacg
      301 acatattcat taatcattat tctcttgaaa aagaattaac aaaagaggtt caagatgaat
      361 atatctctgc aaggttacct gataaggcga gggaaattaa ggattttatt tcttattcaa
      421 taggttgtat cttcggtcgt tactccctag acgaagatgg tctcatcttc gctggcggcg
      481 aatgggatcc ttcccgctat caaaaattta aacctgatac tgataatgtt ttactcatca
      541 ccgatgatga gtatttcaag gatagccaaa ttgacattgt caatcgtttc attgatttcg
      601 ttgagattac ttttggtaaa gaaacccttg aagaaaatct ccagtttatc gctgacactt
      661 taggtggcaa agggacaagt cgagaaatta ttcgtcgtta cttcgtacaa gatttttaca
      721 aagaccattt aaaaacatac tccaatcgac caatttattg gcaattggac tcaggaaaac
      781 aaaatggctt taaagcgtta atgtacttgc atcgctatac accagatcaa ttaggaaaag
      841 tacgtactga atacctacac gaactacaaa aagcgtatga caatcgaatc gaattgcgtc
      901 agcaacaaat ttcaacaagt gataacccaa aagaaagaaa tgcaatgaca aaagaaattg
      961 taaagattca gaagcaatta aaagaagttc gtgagtatga cgagaagttg ggtcacttag
     1021 cattaaaacg aattgaatta gacttagatg atggtgtaat tgtcaattat gataagttgc
     1081 agcgtgatcc taaaaccggc gagaaattcc aaatttttgc aaaaggggtc aaagaaccaa
     1141 aaaaatagtt atctaagaaa gttgttttct aacaactttc ttttttattc ttaaattgcg
     1201 tgcgaaatta tccaaattat gtcaatataa ggggtataga aagagaacga ttaggtgaga
     1261 ttgatgacag atataaatac gcaacaaatt gaagaaaaat taaatcaacg ttttcctaat
     1321 tatggatgta ggaaaatcat tttttggttt gattcaaatc aggattttct tgaagaaatt
     1381 gactcattgg tcattcaaaa tgcaaaaatc tatcgattag aaaaggacgc acaatttaaa
     1441 actaagcgtt tattggaata tgaagatccc gaaactaact atttaatcta tgcgccattt
     1501 cctcgttggg atgataaaga tgaagataat catttgttga gtgtattgaa ttattcagag
     1561 gaatttagtg cagaccgctt agcgattatc atgaatgaat tggctattcc acttagattt
     1621 catcagacag ttaaacagta tcgtaatttc tttaatgcaa aggatcgcat gagaagtttt
     1681 ggtgaattta gtacgcatat gacaattaat aaatcagaaa cgattgaatt aatgataatg
     1741 gctgttttgt tgaaatcgaa aagtattcga ttaaatgatt tactgcgtgt agttctaaaa
     1801 agctttacag aaagtaggga gaatccttta agggaacttg ataagtatca gttaacagct
     1861 aaattttggg aatttattca aatgaaattt ggctttacgg atagccagcc aacattggaa
     1921 aagctgacga tgtgtcttta tttgaactat ttttattatc aaattgatca agagatgccg
     1981 aagaagttca aaggatttga aatactacat ttgaaagcaa acattattac tttcatggat
     2041 cagtttatga atgatacacg ttacatggaa agctttgaac agctatctaa aaaagtatat
     2101 caggctattg atggtgatgg attattagac agtatagaaa ttgatgatct aattgaagca
     2161 gacgtatttt ctgagattca tgcaaaaata ttaatgtttt atgcagaacg attaaaggct
     2221 tctgacacta caacgaaaat tgcaggacaa acaatttttg atagtttaaa gcagcgcgaa
     2281 aaaatgcatt tcgcatcgga ttatatttat gagtatcaat tattgaaaca tgcttattat
     2341 cttgtggata aaaacagatt gtgcttgccg atgaacatgg ataatttgct aactcaatat
     2401 gagaaggaaa tgtattgggt tgatacgcat tatcggaaat ttatttggaa tagtgatcat
     2461 atagaagaaa agcaaaaata tggccaattg tatcgattag ttgaagcaaa ttattcgaag
     2521 tttcttgatc aatcaggaca aatttggaat caaacttttg aatttaagaa tcgtccatcc
     2581 attcgaaaat tttataatca agctgtaatg aaacgctctg ttaaaactgt agttattatt
     2641 tcagatgctt ttcgatatga gttagggatg aatttagaac gtaagttagt tagagaaaag
     2701 aagtattcaa caaacatggc tagctttctt tctgtattac cttcagttac tgaattcggt
     2761 aaagccgcct tattaccaaa caatcaacta acttacaatg aaggaacaga agtactgatt
     2821 gatgggaaaa aaacgaatgg tttatccaat cgaaatgcga ttctccagca acgagatgca
     2881 aatgctgtag ctttaaatta tgatgatgtg gttaagatga ataaggctga ggtacgagaa
     2941 gtatttaatg gcaaatcagt catttatatt tatcacgatc aagtggatag aacaggtgat
     3001 cactcgaatg aaaatcgagt ttttgaggcc tgtgatttag cgataagcga aatttcccga
     3061 cttattaatc gcttgcataa tgatggcagt atctatcgtt ttatagttac ggctgatcat
     3121 ggatttattt ataaaagaag ccacgttgaa gaagtagata agattgaaaa tccatctaga
     3181 aatgaaaaag atcgtgtaga acgtcgtttt attcttagtg aagaagaata cgaaataatt
     3241 ggtacgaaaa attactcttt gggagattct ttaggaaatg atgacactag aaacatttgt
     3301 gtcccgatta cttcaagtat ttttaagaaa gctggcgggg gacaaagcta cgttcatgga
     3361 gggtcatcta ttcaagaaat gctagtccct gttctagaaa ttacggtagc caaaggtagc
     3421 aatgcaaagg aaccagtagc aattgaatta atgactagca accgcagaat tacaggatta
     3481 tcaaccacgt tagaattcta tcaaaaaaat gcaattagtg atgtttatga ccccgcatct
     3541 ttctggcttt attttgaaga tgaatatggt gaacgtatct caaatgaaga aatctatgtt
     3601 gcggattcaa aaacagaaga tgcaaatcag cggtttacta aatttgtttt tgaatttgta
     3661 aatcgtcgat atacagttga agatacttat tatttagtga taaaaaatca aaaaaatgat
     3721 ttgaccgagc gaataaaatt cattatagat aatccttttg cagaatcatt tgattttgat
     3781 atataaaaac gaggtatcca caatttt
//
LOCUS       DAZUJR010000154         3721 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.159, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000154 DAZUJR010000000
VERSION     DAZUJR010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3721
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.159"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..356)
                     /locus_tag="ACG804_002825"
     CDS             complement(<1..356)
                     /locus_tag="ACG804_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833689.1"
                     /translation="MKKFKKKIYLGLVVGVSMFGFMAHTKQVTADTNQKERIMSQLDD
                     SQIEYVPNELIVSLKATQRISTEKNKPQNLLGVKVMVEKDLTLRINESDYNKRDQVLL
                     VKLNEEISVEEAVRTF"
     gene            complement(616..1164)
                     /locus_tag="ACG804_002826"
     CDS             complement(616..1164)
                     /locus_tag="ACG804_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833690.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            complement(1165..2022)
                     /locus_tag="ACG804_002827"
     CDS             complement(1165..2022)
                     /locus_tag="ACG804_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFS4833691.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            complement(2308..2594)
                     /locus_tag="ACG804_002828"
                     /pseudo
     CDS             complement(2308..2594)
                     /locus_tag="ACG804_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(2584..2913)
                     /locus_tag="ACG804_002829"
     CDS             complement(2584..2913)
                     /locus_tag="ACG804_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFS4833692.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            complement(2990..3262)
                     /locus_tag="ACG804_002830"
     CDS             complement(2990..3262)
                     /locus_tag="ACG804_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFS4833693.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            complement(3262..3525)
                     /locus_tag="ACG804_002831"
     CDS             complement(3262..3525)
                     /locus_tag="ACG804_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFS4833694.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
BASE COUNT         1092 a          754 c          473 g         1402 t
ORIGIN      
        1 ttaaatgttc ttactgcctc ttccacacta atttcttcgt tcaatttcac taataatact
       61 tgatctcgct tattataatc gctttcattt atcctaagag tcaaatcttt ttccaccata
      121 acttttacac ccaataaatt ttgcggttta tttttctctg ttgaaattct ttgtgtagcc
      181 tttaaactga caattagctc attgggtaca tactctattt gagagtcatc taattggctc
      241 ataatccttt ctttttggtt agtatctgca gttacttgtt tagtatgagc catgaaccca
      301 aacatactca ccccaacaac caatcctaaa tatattttct ttttaaactt tttcatctac
      361 atctcctcct aatagtttta ttttagagtt agctctatta cttatttact aactcaacaa
      421 cagattatca tacacttgtt aatgaaatca caatatctca ttaaaacaca ccctaaaatc
      481 ataaccgttc ctatgctcat tttttggatt ttttaatcac gtaaccagaa aaataaatcc
      541 cctctatttc acgcaaatca aagaagaact aagtaactac cgtttaaagg tagttactta
      601 gttcttcttt gattattatc taactttatt attcattccc caccctttgc gcagtgagtc
      661 ttcggtatct tgttttatct gactggtagt tcttattatt tctccacgat catctaattc
      721 tggaacaatt ggatattttt ctctgaacaa gtctagttct ttcaccacgt cattaaacaa
      781 atcttgctta tcttcttgcg taagattctg tttaatatac tcatctaaag cttttctaag
      841 caattcatct cttgtcatat tagtctcata cttttctact aaaactctgg aagtcgcatt
      901 taacaaagtc gacagtttta aaggatgctt ggtggaataa accttatcaa actttctgat
      961 tggtgcgcca actttttttg ttcttcctct actctgtctt tcaacattgg aggaagtttt
     1021 tatttcttga acttggtgca cttctaattg cttattttca gatggtgtaa ttgcttgctg
     1081 ctttttcttt gcttctgctt ctttttttat tttggcgagt cctttgttgt tcccaaaaat
     1141 atcaagtcct ttgatgtcag ccaattactc cacctccgca taccaattct cgtgttcttc
     1201 caattctttc aaaatactga taaataattc gtggcttttg cgatcccatt gttttaagag
     1261 acctttcttt gtcttctcca tcgtaatacc tgatccgtcg tatcgtttta agcgcgcatt
     1321 tttgagtaca acatttttaa tcaaatgttc cccataaatc tcttgggctt gtttatacat
     1381 ttcctgatct actgcgtcac cgctttccaa catgaaagga ataacaccag caacatataa
     1441 atttgtatca aattctttca caaaaaagtc catatactca agatattgca tcgcatttct
     1501 catcgatttt acttgggtct gtaagacgac gattgcccaa tccgcaatgt acatcgcgga
     1561 tttactatat acagaaatag aaggtgggac atctaaatag atgacgtcaa actcatcaaa
     1621 taatggttct agcttttctt tcatatattt gaattgggat aatgaatcat tatattggtc
     1681 tttgatccaa tcatcataca tttcaaagga catgtctgct ggaagtatat agaggttatt
     1741 gattacttta tagacagcct ctttaggtgg aagattgttt atcaacacgt cagtcacagt
     1801 attttcgtaa acaatcggtt caccttctcc gcctccttct tcgttagtga agttcatatg
     1861 cgttaagttc atcacatcag aagtatttcc ttgcatatcc aagtcaatta tcaaggttct
     1921 ttttccttca ttaactgctg attcaaaccc taacatttgc gcgcacgtac ttttacctac
     1981 gccaccttta aaattaccga ttacatattt cttcgctacc acgttcctac ctcttttctt
     2041 ttagcaatat tcatttgata ctattataac atatttattt ttagttacta ccaaaaaaaa
     2101 gatatatatg tactacctta taattaataa gtaaaaggta gtacataaat aaggaaaagc
     2161 tgaaatatat tgatttatag ctttcctcaa agtaatgacg ttatttaatt tatcgagaag
     2221 cagagaatac tcgcgacttt agtcatgtag acgaatcaga ttttcgataa aaaagaagcc
     2281 gtccttctta agaacgacaa caaatcacta gattaatttt ttcaactgtt cataaaagtt
     2341 ttcatgcgtt ccacataaca atactggaat aaccttgttt tctataatct cgtaagctac
     2401 tctatatgtt gtgcccgcat atttgaaccc actagaccaa atacctgata aatccccagt
     2461 tttttgttca cccttatatg gatcaatcgc aatttcatca taaattaaat tcaaaaattt
     2521 ttctttcaat ggcttctctt ttagcttttt aaatacttaa tgacatgttt tgaaggaacg
     2581 atttcataag ccaatttctg ttgccaactc ctctttagtc attactttag aattagtaag
     2641 tgtatcttca gcaatatctc taaaggaaga atgcattttg ttttttctat tcttaaattc
     2701 tacaagaatc tcatctttat cgtagccttc tgcaattata tcagacaaaa tatcttcgct
     2761 aaaatcataa aattcttttt gtggttcaac aaattcataa agaataccat tctctaccaa
     2821 ctttgcttca acttcgactc cattaggaac attaaaatct ttaggtactg tcaacatgat
     2881 tgaattgcct tgttttcttg tttttgtaat catttaaatc cctcatttct aacagtatgt
     2941 aattacttag taaatacatt ataccacgag ataatgtatt tacaagtaat tactgtgact
     3001 cgtaatgcgt ccttgctgaa taaatttcaa ccacgtgttc atcttcatct accttataaa
     3061 caacccggtg ttgtctattc aatcttctag aatacctacc ttcatgtgta ggttttaact
     3121 tctcaaatga ttgggtaggg agatagggat cttcctttaa agtctgaata accttctcaa
     3181 attgaggttt caaattagac tgtttgattt tctttaaatc agctttagcc gagtttttaa
     3241 tcatcacaga atagttattc attataagtt atcccaatca atttcatcaa cattagtaaa
     3301 tccactatca tctttttctc gcttacgaac aacacccaaa gtgcctattt gctcaagtaa
     3361 tagcgtttct ttgattgctt tccaatcatc caaaccaata agcaccgcat tattttcact
     3421 gcgctcacta atgatttcaa tttccgtatg attctcattt acatctttca acaacttata
     3481 aaaatttttc cgtgctgagc taggatttaa gactgttttt gccatatcta ctccccctct
     3541 aatttatatc tccattctaa cgtacttaat taagtacgta aattcgattg ttttgtttaa
     3601 attggagtac caaaacagca ttgtaaagtg ttatccgttt cctttatacc cgtggtgcta
     3661 gttaattttt tcctagagga aaatgtctaa acatgttggt aaatcaacaa aaaaacgcat
     3721 a
//
LOCUS       DAZUJR010000155         3558 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.160, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000155 DAZUJR010000000
VERSION     DAZUJR010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3558
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.160"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..698
                     /locus_tag="ACG804_002832"
     CDS             <1..698
                     /locus_tag="ACG804_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFS4833695.1"
                     /translation="KDTWKNIKDTAYNTWISIKNTMINTWNNIKDSFWNIVTGIVNSA
                     ENAWTNLKNGVSNAINRVKEIFNSLREVNLFEIGKNIIDGLINGVKEKWNALKDTIKG
                     IAGNIKNWIKGALDIHSPSRWMRDMVGKNIVQGIIVGIDKEQSKLDQTMTNLVKTPSV
                     QPVVNGISHLPITQTKQNISASETKEIHLHLNVYGDLPDSMVRKITTKIKTELTRQMK
                     RDAGAVGGTLYAT"
     gene            688..1428
                     /locus_tag="ACG804_002833"
     CDS             688..1428
                     /locus_tag="ACG804_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4833696.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKGYYKNVTRKIECYYKAPSIDMVQEWEDRITEWLDMSSYSDFILYYDEQYIYQ
                     AVVIEGPEFKGTRKTGNIVPFEFTVSIRPFKENYNGRFTIRQTETFEIYNPEKYSSKP
                     LIKLSGSGDASFYINKDKYDLKSLDRELFIDSKLEEAYRKLDGNLEHQDQVTLFLDFP
                     FLYPGKNEIKWTKNIHSFEIMPRWWRKV"
     gene            1425..>3558
                     /locus_tag="ACG804_002834"
     CDS             1425..>3558
                     /locus_tag="ACG804_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HFS4833697.1"
                     /translation="MKPRIYSPTETDFSTNGLGILKDCTRCGIYEVANGKYELELDYP
                     LGTRFDEYFENDYQIKAKPNDQEEYHIFFIDDKDIDTFLNTVTIYAQSRTNRLGRRVV
                     TLVEVDSKTGQEAISIIETKMDKKSDIRLYSDITAVSSTIFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRNNVGTIRYGKDMSGLKVKLDWTGIKTRIIPYADPQS
                     EVGTTNRIYGSPVDSAYINNYPDVYTEHVQFTEEQGVKDIKSLNKIAKNYFKTINPGC
                     DKPKVSITVEFDKLTDSEEAKEFAKIRNYGLFDTFKIYHKKYNIYLESKVSGLQYDSL
                     SEKTLKLEAGDIQVAFYQQQAVTIQDKLKDYATNNYMSDFNDYVSSMITGQGSAGGYV
                     VLWPKEKPSNIFIMDNPDLEKAREVLRMNKNGIAFSKKGWRGPFNSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSKGSIGTI
                     GTTDSVGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVKGKEIIPGQGGGPSGGGESTGGYPSELKTDAEKRAWRIYDILCNNGFTK
                     QSACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWDGKVYVQNLF
                     NAAGIKEPITSLDAQVRLLIWTFTNGQWM"
BASE COUNT         1321 a          441 c          699 g         1097 t
ORIGIN      
        1 tcaaagatac ttggaaaaat attaaagata cggcatacaa tacgtggatt tctataaaaa
       61 ataccatgat taatacatgg aataacatta aggactcttt ctggaatatt gttactggaa
      121 ttgttaattc tgctgaaaat gcatggacaa atctaaaaaa tggtgtttca aatgctatta
      181 atcgggtaaa agaaatcttt aattcgttaa gggaagtcaa tttatttgaa attggcaaga
      241 acatcattga tggacttata aatggtgtaa aagaaaagtg gaatgctttg aaagatacta
      301 tcaaaggtat tgcaggtaat atcaaaaatt ggattaaagg agctttagat attcattctc
      361 catcaagatg gatgcgtgat atggttggta aaaatattgt tcaaggtatt atcgttggta
      421 ttgataaaga gcaaagtaag ttagatcaaa ccatgacaaa tttagtaaaa acaccgtctg
      481 ttcaacctgt agtaaatgga ataagtcacc taccaattac acaaacaaag caaaatatat
      541 ctgctagtga aacaaaagaa attcatttac atttaaatgt ttatggagat ttacctgatt
      601 caatggttcg gaagattacc acaaaaatta aaacagaatt gacaagacaa atgaaacgag
      661 atgctggtgc agtaggagga acattatatg caacttaaga gaggacaatt ttttattaat
      721 caacattatt cttctgaatt taatgtgtat attcaaaaca ggcctgcttc tgtttcagct
      781 agtcgagtaa ttgaattgag agagcgagaa ggaaatgatt ctatcattat tgataaaggc
      841 tattacaaaa atgtgactag aaagattgag tgttactata aagcaccttc aattgatatg
      901 gtgcaggagt gggaagatcg aatcactgaa tggttagata tgtcgtctta tagtgatttt
      961 attctttact atgatgaaca atatatttat caagctgtag taatagaagg acctgaattt
     1021 aaaggaacaa gaaaaacagg aaatattgtc ccttttgaat ttacagtgag tattcgacca
     1081 tttaaggaaa attacaatgg tagatttact attcgacaaa cagaaacttt tgaaatttat
     1141 aacccagaga agtattcttc aaaaccgctt attaaattga gtggttctgg agatgcttct
     1201 ttttatatta ataaggataa atatgatttg aaatcgttgg acagagaatt atttatagat
     1261 tctaaattag aagaggctta tcgaaaatta gatggtaatt tagaacatca ggatcaggtc
     1321 accttatttt tagattttcc atttttatat cctggaaaaa atgaaattaa atggacgaaa
     1381 aatattcatt catttgaaat aatgcctagg tggtggagaa aagtatgaaa ccaagaatat
     1441 atagtcctac tgaaacagat ttctcaacga atggcttagg aattttaaag gattgtacaa
     1501 gatgtggaat atatgaagta gctaatggaa aatatgaatt agagttggat tatcctttag
     1561 gaactagatt tgatgaatat tttgaaaatg actatcaaat aaaagcaaag ccaaacgatc
     1621 aagaagagta tcatatcttt tttattgatg ataaagatat agatactttt ttaaatacag
     1681 taactattta tgctcagagt cgtacaaatc gacttggaag acgggtagtc actcttgtgg
     1741 aagtggactc taaaactggt caagaagcga tatcaattat tgaaactaaa atggataaaa
     1801 aatctgacat acgactttat tctgatatta cggctgtttc tagcacaatc tttgaagcga
     1861 gaaatgtttt aaattgtatt gctggtgaac aaggatcatt gcttcaatat tggggcggag
     1921 aaattaaacg tgaaccattt aagctttctt tgttaaagcg aagaggtcgc aataatgttg
     1981 gaacgattcg gtatggaaaa gatatgtctg gtttgaaggt caaattagat tggacaggta
     2041 taaaaacaag aattattcca tatgctgatc ctcaaagtga agtaggtacg actaatcgaa
     2101 tttatggttc gccagtagat agtgcctata ttaataacta tcctgatgtc tatacagaac
     2161 atgttcagtt tacagaagaa caaggagtaa aagacattaa gagcttaaat aaaatagcta
     2221 aaaattactt taaaacgatc aatcctggct gtgataagcc taaagtttct attacggttg
     2281 aatttgataa gttgactgat agtgaagaag cgaaagaatt tgcgaagatt agaaattatg
     2341 gtctgtttga tacatttaaa atatatcata aaaaatataa tatttatctt gaatcaaagg
     2401 ttagtggact acaatacgat tctttatctg aaaaaacttt gaaattagaa gcaggagaca
     2461 ttcaagttgc tttttatcag caacaagctg taactattca ggataaatta aaagattatg
     2521 caacgaataa ttatatgagt gattttaatg attatgtttc ttcaatgatt acaggtcaag
     2581 gcagtgcagg aggatatgta gttttatggc caaaagaaaa accttccaac atctttatta
     2641 tggataatcc agatttagaa aaggcaagag aagtactaag aatgaataaa aatgggattg
     2701 ctttttctaa gaaaggatgg cgggggcctt ttaattcagc ttggacatta gatagtatat
     2761 ttaatgccaa ttttatacaa actggattaa tcaaagcaga tatctttcaa aattctttta
     2821 acaagactgg agatgtattg aaattagtta atggactact ccaaatttgg aacaacaaaa
     2881 agaaaataat ggagttaact aaaaaaggaa tggaattttg gaattctaag ggttcaattg
     2941 gaacgattgg aacaactgat tctgttggta atccttttcc tggggcttct actccaaccc
     3001 ctattgaaga taattcttta gttattcgta caaatggaga cggcaaatat attttgattt
     3061 ctcctaaagt aggaaaagga ttagttttat taggaaatgg taaagcaatt tattttggag
     3121 acttagatgt acaaggaaaa cttacagtta aaggaaaaga aataattcct ggacaaggtg
     3181 gtggtccatc gggaggtgga gaatctactg gtgggtatcc tagtgaatta aaaacagatg
     3241 cagaaaagag agcttggaga atttacgata ttttgtgtaa taacggattt acgaaacaat
     3301 ctgcatgtgg aatattgggg aacattcaac aagaaacagg aggaactttt gatcctgata
     3361 ctgttcaaat aggtggacca gcatacggat tagttcagtg ggatggttct tcatatcctc
     3421 ttgttggtcc agcaacatgg gatggaaaag tttatgttca aaacttattt aatgctgcag
     3481 gtattaaaga accaataacg agcttagatg cacaagttcg attgcttatt tggacattta
     3541 caaatggaca atggatgg
//
LOCUS       DAZUJR010000156         3378 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.161, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000156 DAZUJR010000000
VERSION     DAZUJR010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3378)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3378)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3378
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.161"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..2199)
                     /locus_tag="ACG804_002835"
     CDS             complement(<1..2199)
                     /locus_tag="ACG804_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen binding domain-containing protein"
                     /protein_id="HFS4833698.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESLSESFNEARSSEPSITQESQIER
                     QEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVRVPRASIGLIEF
                     IRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITFEVAFFQSGGTE
                     PNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGNLGNLLIDGQDV
                     TNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREPISGGVRIAEVT
                     NPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYALEVTDVDLFNE
                     GRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNVINLNENELTYT
                     LHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRFSANNTIGGPTS
                     FTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKVIKTDENGQRLA
                     GAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYLLDATVHDVFIN
                     EYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGETLQTG"
     gene            complement(2871..3139)
                     /locus_tag="ACG804_002836"
                     /pseudo
     CDS             complement(2871..3139)
                     /locus_tag="ACG804_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
BASE COUNT          937 a          752 c          541 g         1148 t
ORIGIN      
        1 accggtttgt agcgtttctc cttctcggtt ctgtaactca aaaacagctc cttgaaggac
       61 ttcaccactg ccttcagcat gtttaattag ttcaacacca cccgtatcaa ggatgttttc
      121 aatggttaac gtcacttctt ctatggagta ttcatttata aaaacatcat gtaccgtcgc
      181 atctaaaaga tacccttccg gtgcttctgt ttctcggact tgatagctac ctacaggaag
      241 cggttcactt aaaaattctc cgttttctgc cgttatacct tcttgtatca cttgtgaatc
      301 gcttgataaa atttcaaatt ttgctcctgc cagcctttgg ccattctcat cagttttaat
      361 tactttaata cgcccatcga ttttccttgt tcttacagta ctcgtattca atcgattgtc
      421 actattcaca agcgttgcaa agtttaaaat ttgatcgccg accgcatacg cctctacatt
      481 gaccttaaaa gagagggtaa aacttgtcgg accaccaatc gtattattcg cactgaaacg
      541 aactattcca ttattgactt cggcatcaat gaaagaggga atatctgata gaaatgacac
      601 aaattccatg ccttcttcca aaacatcttc aataacaagc gtatttcttg ttccagaaaa
      661 catcgagaca tgcagagtat acgttagttc attttcattg agattgataa catttttgtc
      721 cacacttttt cttaaagaga ttgccggaag attactttca gggattctca agcggtagtc
      781 tcggctcatt acctgattat tgtaggtcat actcgctcga ttccgagaaa acccatcctc
      841 ttgtcttcct tcattgaaca agtcgacatc ggtcacttca agagcatatt caataaaata
      901 cgattgaccc tctgctagat taccaaagtc cacaacaagt gtattcgttt ccttattaaa
      961 agatactttg tccacaaatt cctcggaaac ataatgagtt ctaacgtttg cttcacctgg
     1021 attcgttact tctgcgatcc gaaccccacc tgaaataggt tctctatttc cagtggaact
     1081 ccatgtagtc ggattcggtg ccaaagttgt tccttgcggt agtacatcgg taaccactac
     1141 accgtctttt cgtgatcctt cataatttac ctgcaaaata aatttattac tgttggtcac
     1201 gtcttgcccg tcaatcagca gattcccaag atttccttgg ctgtcgattt ctctagagcc
     1261 atagtataat ttcgaaaaaa tgggtcttga tgaaggaata ggcgtaattg aaaattccgt
     1321 gtttgctgct cgctcagcat aagtaagact cacttgaaag tcattatttg gctcagtacc
     1381 gcctgattga aagaaagcaa cttcaaacgt gatactgaat gtatacgact gagcggcttc
     1441 atttaatcct tcataatcaa aggtaaatgg aaaaacaacg tctgtgcctt cttggtaaaa
     1501 tgccagtggc tttaaaggtg aatcatcagc gacctccact ctaatgaact caattaagcc
     1561 aatcgatgct ctaggaactc gtacgaccat ctccccatat tcttcaagaa tatcgccagc
     1621 gcctccttga atgtatccct ttaacgtttg tgtatgcctg ctcggcaaag tggggcgctc
     1681 agcagagatg ccgatgtcat aattcaagag ctcctcttgt ctttcaatct gagattcctg
     1741 cgttatagat ggctcagatg atctggcttc attaaaagat tcacttaagc tttcttctgg
     1801 tacattaaaa gactcacttg tgctttcttc tggtacactg atttctattg agaccgtatt
     1861 tgattgaata tcaccgcttc ttgcggtcaa ttcgtattta cctgaatgct gggaagaata
     1921 agtaatcaga cgttcgtaat cattgagttg cttcacttcc ccttcaatca aatcctcact
     1981 cttatcaatg accaatgcat ttagcaggtc tggtgttcct ctgactcgca actggaactg
     2041 ctcacccaaa gcagcctcct cttgatcaac ttcgatcgtc agcgaacgct ctggctgttc
     2101 tgctaaagac tcagctagaa ccgttatgtt cccaaattga ttgatcacaa taagcataac
     2161 tagaaacata cttaacagtt tatgaaattt gttcctcact attactcccc cttataattt
     2221 tgactaaaca acaaggtacc cgataatttt ctaaaaagat tccccaactc aaaatggctg
     2281 cgttacctcc ctcgtatttt cggttcaact caagcgttgc aatgtaagct gtaaacaaag
     2341 ctaatgattg ccgattgtct tctgttgatt gattcgatag ctttgtatga cttttagttg
     2401 tccgtgtggc ttaaccataa ttatgatttc acgattcctc ctgccagtgc cttgcacaag
     2461 ctggagcgta accctaatag ttattttgtt aatgtactta tatactttta tacttttcca
     2521 ttagaaacaa tcactaaatc gttgatacca aggtcagact ctagaatttc atcagtgagt
     2581 ccctgtattg gttaaccttc atcaatccca aaaaaatata tcaatgctta gcatcaaaat
     2641 gaatatatag tttagaatac ttgggattca tcgataactg atcgcttatt tggccatatt
     2701 atttggcact tggttcaact aaacgcattt aggatgttcc ttcattctcg tcatggatgt
     2761 tctcaaaccg tcattactaa taaactgtcc accgaatcga tggttcattt cttgcatttt
     2821 ccacgtccaa ttactctttt tgctctttat ttgggcgtag tttcactttc ttaacttgta
     2881 tcgtcttcca tcaactcctt aatcatcttc ttagctttat tggctcggtt tccttgtaaa
     2941 aggtatctac aaatagtgac aatctgtatt aaatcttcat cattttctgt aatgtcaata
     3001 atttctatat tctgtaccat atattgcaaa gggtttcact aagttcataa ccgaagcgaa
     3061 ttaaacaact tttgtataga ataactacct tttctatttt tccattggta attctatcta
     3121 ttaattggtt taatcctttt gttgtagttg attccactac caagatgatt ctctcgaatt
     3181 ttaaagcttg aagatgtatt gctatttttg ctaactggcg tatttgcaac tatttttccc
     3241 ttctattctt ccttcattga ttcccctcta aaattactat ccataaaaaa ttgcataaat
     3301 gacaatagta tttatattag tcatactgct ttttaacaca gcaaattcca gaaaaacatt
     3361 cgttacatat ttgtgaat
//
LOCUS       DAZUJR010000157         3343 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.162, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000157 DAZUJR010000000
VERSION     DAZUJR010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3343
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.162"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..189
                     /locus_tag="ACG804_002837"
     CDS             <1..189
                     /locus_tag="ACG804_002837"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833699.1"
                     /translation="DLEKLTKQRDMKNFNNCVVLIIITELTLFTNIYYIHEAQSSLIE
                     DWAIFMAKEGKEMFQNKG"
     gene            202..477
                     /locus_tag="ACG804_002838"
                     /pseudo
     CDS             202..477
                     /locus_tag="ACG804_002838"
                     /inference="COORDINATES: protein motif:HMM:NF017894.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
     gene            504..803
                     /locus_tag="ACG804_002839"
     CDS             504..803
                     /locus_tag="ACG804_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HFS4833700.1"
                     /translation="MLETAIEVLEKCAQLVTASEEWGYESVTMEKEEIEMGMLPEDVH
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTDE"
     gene            977..1528
                     /locus_tag="ACG804_002840"
     CDS             977..1528
                     /locus_tag="ACG804_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HFS4833701.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFLRGNDEQSLE
                     ILTTVFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            1674..1967
                     /locus_tag="ACG804_002841"
     CDS             1674..1967
                     /locus_tag="ACG804_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mor transcription activator family protein"
                     /protein_id="HFS4833702.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            1960..2256
                     /locus_tag="ACG804_002842"
     CDS             1960..2256
                     /locus_tag="ACG804_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833703.1"
                     /translation="MAKLIVLGGLIYGGYWLYQYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHTGYRHYWERID"
     gene            2331..3329
                     /locus_tag="ACG804_002843"
     CDS             2331..3329
                     /locus_tag="ACG804_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HFS4833704.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKATIETDTTIETKKSKTQS
                     TEQTTTEMKQSVETSASSITESSSEEVKNTLWDTNKASKLETFVTQWGKTLGQEYKSY
                     NLQNNVSLYGTPLPQAVINGDWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVETGE
                     YLGQHVYFFGFQNGQPKVYLTQQNQGNENNYLYFNETQNQQLKQGFSDIVNGQTPQTP
                     VVEESTQQATTTTTQSTSSSGISSWEAAKESVLNNKALWLYDSPDKNVSNTNLISTNE
                     YMKDLMQDENGSYYSINIVTDDDGNTTMAGGKQFRVYTDGRISQRIGMTNNFQMIK"
BASE COUNT         1255 a          458 c          663 g          967 t
ORIGIN      
        1 gatttagaaa aacttactaa acaaagagat atgaaaaact ttaataattg tgtagttttg
       61 ataattataa ctgaattaac tttatttaca aatatatatt atatccatga agcccaatct
      121 tctttaatag aagattgggc tatttttatg gcaaaggagg gaaaagaaat gtttcaaaat
      181 aaaggataac gttatgtcac aaagggagta atggacagtt tgccggtgga attacaagct
      241 ttatgttgga atctaatcga tcaaaacgtt caaaagcaat ttcctttaga ctatcttcaa
      301 atttttgaat tttctacgga aaaaggaaat caaaagttgg ttcatcgtca agaagaaccg
      361 gaagaaagaa aagagtatct gatttcacct aagcttcgtt tgaaatcagt gtctcaaaaa
      421 atatgggcca ttgattcggg tgagtatcaa acgatgttat taccagaaga atactagtat
      481 ctaaaagaaa ggaacgaaag gacttgttag aaacggctat cgaagtactg gaaaagtgtg
      541 cacagctggt cactgcttct gaagagtggg gctatgaatc cgttacgatg gaaaaagagg
      601 aaattgaaat gggtatgctt cctgaagatg ttcatctacc acgtttagtg atgacacatc
      661 tttatattta ttgcgcacca gaagatggaa aagactatgt agtttatttc attacagata
      721 ttaccagcca gcgagaattt gttcgtgggt tactggtaga aggacgattg gtttggagtc
      781 agattggagg aacggatgaa taagatcgat tatttgagaa tgattgcgaa atgtttagaa
      841 gatatcctta ccgcgattca tcaaattctg aagaaaaaag gagaaagaat atgaaatatt
      901 ttcaactagt attgacactt ataacggcaa tggtaattga agtgcttgaa caaaaaatag
      961 cataggagaa aaagagatga ttgaaaaaga attagtgacc acacaaacag aagtttggcg
     1021 agatcctcat catacccatc gctatgtttt caaacgacaa tgggcgatca aaggaaaaga
     1081 agcggaagat aaattagcag tagtcattac tattcgtcca acagatacag aaccatttac
     1141 gaatgatttg agtatgttat taatcgaaaa gaatatccga caattaggat ttactggttt
     1201 tattgctgtg aatctttttt cgtacacaaa agcgaaaagt cctcgggtat ttcttcgagg
     1261 aaatgatgaa caatctttgg aaatattaac gactgttttt acagaaaaga aaatcaatac
     1321 cattattttt gcttgtggtt cgattacagc gacgagtcaa gtggcttatg aacaagcaaa
     1381 gactatttac gatcaattga gtgcgaaaca aaagaagatg accaaagtat tgataaatgc
     1441 agaaggtaag ttatcccacc cactaagtat tcatgttcgt aatgaatggc aattggcaga
     1501 tagtcaatta ttatttcaag aaaaataaca ttttattttc tcatgttact tataagtagt
     1561 tttacatgct ttttgacttt aaaaatacat gtgatgatac atgttatatg aattatcaat
     1621 gtacccagta atatgctatt ttcattatgt aaaaaataac agggggtgtg tagatggaga
     1681 ttgatgaaac ttgtttgagt aactcttata aaagtatgaa tgactttttt gaggaaatgg
     1741 aactggattc agaattgctc tatcaatttt atcttgcttt tcgagggcaa cagatttctt
     1801 ttccaatgaa aatgtacgat cgtgagttag ttagaaaaag aatcgaaaac atgatagaac
     1861 aggaaaaaac tgtagatatc cgtcaattga cagaagttta tggtttctct gcaagatgga
     1921 ttcaaaaagt aattaaacaa aaagaaagga gacgagtaca tggctaagct gattgtatta
     1981 ggtggtttaa tttacggtgg atattggtta tatcaatata tgcttgcgca tccgaatata
     2041 gataaaggaa aagtaattaa gacagttggg gtaatcatag ttggactcat agctctaact
     2101 aagaaaaata atactaatag cccaaaaata atgagaactt atcgctgtag aggatgtgga
     2161 agggaaattt ctactagttt taatccatct gagagtcctc aaggaagaga ccgctgccat
     2221 acgggctatc gacattattg ggaaagaatc gattaaaaga ttaccattta gatcaattaa
     2281 ttgtctgata gaataagtac gtgagggaga aattgaaagg gggaaatata atgaaaaaat
     2341 ggctgttatt actaatagga atgggaattt tattcactgg ttgtacatct gagaatacga
     2401 ggactaaagc gactatagaa actgatacaa caattgagac taaaaaaagt aaaacgcaat
     2461 caactgaaca aactacaaca gaaatgaagc aatctgtgga aacaagtgca agttcaatca
     2521 ctgaatcttc ttctgaagag gttaagaata ctttgtggga tacgaataaa gcttccaaat
     2581 tagaaacttt tgtcacacaa tggggaaaga cattaggtca agaatataaa agctacaatc
     2641 ttcagaataa tgtaagtctg tatggcactc ctttaccaca agccgtgatt aatggcgatt
     2701 ggaaaatggc aatcaatgaa gcaccagtta ccgtacaatg gtcagaagat ggaactggtc
     2761 atgcagattt caatttagta gcagtttatt ctgatgtaga aactggagaa tatttagggc
     2821 agcatgttta ctttttcggt tttcaaaatg gacaacctaa agtttattta acgcaacaaa
     2881 atcaaggtaa tgaaaataat tatctgtact ttaacgaaac tcaaaatcaa cagttaaaac
     2941 aaggtttcag tgatattgtg aatggacaaa ctcctcaaac accagtagta gaagaatcta
     3001 ctcaacaagc aacaactaca acgacacaat ctacaagtag ttcaggaatt tcaagttggg
     3061 aagctgctaa agaatctgtg ctaaataata aagctttatg gttgtatgat tctcctgata
     3121 aaaatgtatc aaatactaat ttaattagca caaatgaata tatgaaagat ctaatgcaag
     3181 atgaaaatgg aagctactat tcaattaata ttgtaacgga tgatgatgga aacacgacca
     3241 tggctggtgg aaaacaattt cgtgtttata cagatggaag aatttctcaa cgtattggaa
     3301 tgactaacaa ttttcaaatg attaaataat tgaaaatatt att
//
LOCUS       DAZUJR010000158         3295 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.163, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000158 DAZUJR010000000
VERSION     DAZUJR010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3295
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.163"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            145..336
                     /locus_tag="ACG804_002844"
     CDS             145..336
                     /locus_tag="ACG804_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4833705.1"
                     /translation="MNTLKEDFILAKNGNEEAVVAILKRFSALVHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            850..1182
                     /locus_tag="ACG804_002845"
     CDS             850..1182
                     /locus_tag="ACG804_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFS4833706.1"
                     /translation="MKKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            1092..1295
                     /locus_tag="ACG804_002846"
     CDS             1092..1295
                     /locus_tag="ACG804_002846"
                     /inference="COORDINATES: protein motif:HMM:NF024673.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFS4833707.1"
                     /translation="MFYEHKDRYGSPGITQKLYDEGIEINKRVVAVLMREMNLCTRGF
                     HRRKSSHGREKTIKEMVKKMLNR"
     gene            1326..1472
                     /locus_tag="ACG804_002847"
     CDS             1326..1472
                     /locus_tag="ACG804_002847"
                     /inference="COORDINATES: protein motif:HMM:NF012870.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833708.1"
                     /translation="MTDITYIPCNDGRLYLSTYIDLATRILRYYMVDSHMKKEIVVRP
                     LQIY"
     gene            1910..3250
                     /locus_tag="ACG804_002848"
     CDS             1910..3250
                     /locus_tag="ACG804_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFS4833709.1"
                     /translation="MSYSEFTKELLDILDLNLTFHEDAFRKERINDETCFVFDGTLTY
                     QPEECFHCHYQNKQTIIKWGWKKVSILLNDVSNYKTIVRINKQRFKCKHCGKTFLAED
                     SVSDRRCSIARRVKQAILELLSEPISMSLIARMKHISPTTVIRILRSLRPKTVSLNQP
                     LPEVVCFDEFKSVKNVSGAMSFVMMDGKTHQLIDIVENRQLNPLRDYFLRYPRKVREQ
                     VRLVVSDFYTPYRTLVKECFPNARIVADRFHISQHIGRAFTNHRIQVMKTFKKGDRRS
                     KHLKKYWRLLQKNAWELNGQHRYWRPSFRDHLTEAEIVDRLLYYDDSLKRGYEVYQVF
                     LSAIRRQDVPEFVALLKEDYKELPEHYQPVFTTFKKYRTEIKRALRVPYSNGPIECLN
                     NHIKVLKRIAYGFRNFQNYRERIFLYRGKYFKKTKNTTQLTKARTTTRLDKIAV"
BASE COUNT         1124 a          633 c          597 g          941 t
ORIGIN      
        1 atttaaaaca tcgactttac aaaaaaattc aaaaaatgct ggtttaatat ctgcataata
       61 actaattttg tatgcttctt tgctcgtcct cctccttccc caaaaaataa atagattata
      121 agttcatggg aagaaggtaa atttatgaat actttaaaag aagatttcat tttagcaaag
      181 aatggaaatg aagaagcagt tgtggccatt ctcaaaagat ttagcgcttt ggtccataag
      241 caatcctgga gaactggaaa atatgatcaa gattgttatc aagaatgtat gcttgcaata
      301 tatctagcta tctcgaaatt cgaaattaaa gaataactca actaagggag tctgtgacat
      361 aagtaaaaag atagtttcaa atttcgaaca ataaatttga agccatcttc tttataatta
      421 taaagtatcg attttacagc gttctataat gattcataga atctaaaacg aatgatttta
      481 attattaacg ttttttaatt cgtttttagc ttaaaaataa cttttgtcac agtctcactc
      541 ctaaaattac tttatttacg tacgaagtgg gcaggaggtc gaatccagaa ctgggccatg
      601 gtacttcaac gaggacttct cctctagaat tgaaaagcat gcgatttacc ttccgtaacg
      661 acggtagatt tattcaacta tgtgtccaat caaaatttgt ctgatttcaa aaatagtcaa
      721 gagaattttg gttgttaaaa actcttatct atcaacttcc acagtttagt tgacaaaccc
      781 tgatactaag ttgggctatg atacactttt cttgactatc agttacgtta ccggaaggaa
      841 tgaactctat tgaaaaaaac atatgatcgt aaatttaaac taaagatttc acaggatatc
      901 cttgagaaaa aagtaactac caagaaaatt gctgaagaat acaatatctc tcgtccaaca
      961 atttcccgat gggtttcaga atatcgtcga tacgggaaaa atgcttttgc tggacaagga
     1021 aaaagattac ctgataaagc agatttctac attcttgaac aggaaaataa acgactaaaa
     1081 gaggaagacg agtgttctac gaacacaaag atcgatacgg atctccaggg atcactcaaa
     1141 aactttacga tgaaggaatc gaaatcaata aacgtgttgt agctgttctt atgcgtgaaa
     1201 tgaatttatg cacaagagga tttcatcgac gcaaatcttc tcatggtaga gaaaaaacaa
     1261 tcaaagaaat ggtaaaaaaa atgttgaatc gataatttga acagaaccaa attgatgctg
     1321 tttgggtgac ggatattact tacattccat gtaatgacgg tcgcctctat ttgtccacct
     1381 atattgactt agcaactcgt attctacgtt actatatggt ggattcacac atgaaaaaag
     1441 agattgtcgt ccgtccatta caaatttatt aaggagaatt gcctacggta attcattccg
     1501 atagaggtag ccagcatcgg tcttttattt atcaagagct gttgaccgac caccacatca
     1561 cacattcaat gagccaaact gggactcctg ttgacaatgc agtaattgaa gcgtttcatc
     1621 gatcaatcaa atgagaatta atcgactcca acaaatataa aagtaaaata gagatgaagg
     1681 tgttaatcca agattattta gaagactact acccaaacaa aagaatccat acaaaattta
     1741 tgatgactcc ttgacaattt gaagcgaaga aaataaggga tctataatat ctagtgttgg
     1801 tgacgccttc tgttgccaat actttttctt ttttctaata aacgcaaaca gacaccttga
     1861 aatcctttag aataaagtcg acgaaaacca ttcaaaggag tgtttcaaga tgtcctattc
     1921 agagtttacc aaagagttac tagatattct agacctaaat cttacctttc atgaagatgc
     1981 ctttcgcaaa gagcgcatta atgacgaaac atgttttgtt tttgatggca cattgaccta
     2041 tcaaccagag gaatgcttcc attgccacta tcaaaataag caaacgatca ttaaatgggg
     2101 ctggaaaaaa gtatccatct tattgaatga tgtcagtaac tacaagacca ttgtgcggat
     2161 taacaaacag cgcttcaaat gtaaacactg tggaaagact tttttagcag aagattcagt
     2221 tagcgatcgt cgctgctcca ttgcccgcag agtcaaacaa gccattcttg agctattaag
     2281 tgagcctatt tctatgtctt tgattgcacg tatgaagcac atttctccga ccactgtcat
     2341 tcgaatactt cgcagccttc ggcctaaaac cgtttctttg aaccagccgt taccagaagt
     2401 ggtgtgtttc gatgaattca aatcggtgaa aaacgtctcg ggagccatga gctttgtcat
     2461 gatggacggc aagacccatc aactgattga tattgtggaa aatcggcaac tcaatccttt
     2521 acgcgactat ttcttgcgct accctagaaa agtccgtgaa caagtacgtc tagtggtttc
     2581 agatttctat acaccctatc gcacattggt gaaagagtgt tttccgaatg cccgaatcgt
     2641 cgccgatcgc tttcatatta gccaacacat cggtcgggcc tttaccaacc accgaattca
     2701 agtaatgaag acctttaaaa aaggggatcg tcggtcgaag cacttaaaga aatactggag
     2761 actacttcaa aagaatgcgt gggaattgaa tggtcagcat cgctactggc gtccgtcatt
     2821 tcgagatcat ctgacagaag cggagatagt cgatcggcta ttatattatg atgactcctt
     2881 aaagcgaggc tacgaagtct accaggtttt tctttccgct atcagaagac aagatgttcc
     2941 tgaattcgtc gcgctcctaa aagaagacta caaggagttg ccagagcact atcaaccagt
     3001 gttcacgacc ttcaagaaat atcgaacaga aatcaaacga gcgttgcgag ttccctattc
     3061 caacggccct atagaatgtt tgaacaacca tatcaaagta ctaaaacgaa ttgcctatgg
     3121 ctttagaaac tttcaaaact accgagaacg aatcttttta tatcgaggaa aatatttcaa
     3181 gaaaactaag aacactaccc aactgactaa agccagaaca acaacacggc tagacaagat
     3241 agctgtctag ccgtgtgagt atctcgatta ttctattgaa tttcttcacc aacac
//
LOCUS       DAZUJR010000159         3242 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.164, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000159 DAZUJR010000000
VERSION     DAZUJR010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3242
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.164"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(554..2167)
                     /locus_tag="ACG804_002849"
     CDS             complement(554..2167)
                     /locus_tag="ACG804_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFS4833710.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
     gene            complement(2308..3216)
                     /locus_tag="ACG804_002850"
     CDS             complement(2308..3216)
                     /locus_tag="ACG804_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4833711.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
BASE COUNT         1045 a          556 c          573 g         1068 t
ORIGIN      
        1 tgttaaataa ataggaacaa aaaaattaaa ttatttaata cacacattag ggatcattca
       61 ttgaaggatt agaagacaac gaggatggcg aaaaatatga ttacaataga aaagtcgttc
      121 taaaccaatc agttcctagt atcacacaac gcaagccagt cgatttggtg agattagagg
      181 agtgaaagca aactttatta tataagaaaa aatattcgaa agggatgcta gtttaggtac
      241 tagtgctgat agattaatat gatgcctcgt aatattaggc gtagttactc tagagacatc
      301 actatggact atgatttgtc tcagagtcac aacatgtttt tttatgaaaa gaaacagcta
      361 aaataattaa attgcgcaat gtttaaactt tcttaaacta taacctaata aatgtgaaga
      421 aataatgcac aatttcttca catttatctt ctattctata tacataccaa ccaacaaccc
      481 tatatacttt ttcattttta ctcctcaagt aaaaataact cctagaccgc ggctacccac
      541 cgcggtcgtt tttttattct tcaatcaaaa tcgctttgat acccaaacct gccaagattc
      601 gggcagaagt ataagtattc aatcctcttc tgaaagtaat gtaaactttt ttatcttttg
      661 ggatttcatt gattcgatct cgtaactcat tcattggaat attttttgtt gccgagatac
      721 tgccagaagg tgctttatta ggttcacgta tatctaaaaa gaacgcttct ttcaaatcgt
      781 tttcgggtat atcacttgct ttgatcgttt ctacgatatt cgtcatttga ttgattgcga
      841 cataaccagc tatattcaac gggtcacggg tagtagaata cggtggagag taaggcaact
      901 ccaaatcagg caaatcaaag actgtcaagt ttccggtgat tgctacagaa agttctccca
      961 tccgtttatc gacacctttt tctccaaatg cttgtccacc taaaatacga ccgctatctg
     1021 catcaaaaat cagctttaga tttaatcttg tagcttctgg atagaaatag gcatggtcaa
     1081 agggagtgat aaaaacagtt ttataatttg ttatgcctga tgcttttaat tcatgttctg
     1141 tcattcccgc ataacttgct gtatgatcaa agatttttgc gacacctgca ccaatatatc
     1201 cgcgatagcg cataggcgta ccatttaaaa tatctgccag catatgtcct tgacgattgg
     1261 ccgcactgga aagcatactt tggatcggct gaccagtcac tacactagtc gtttcgataa
     1321 tatcgccaat cgcatagatg tccggcagat tggtttgtaa ctggtcatca acaatgatct
     1381 gacctgtatc tgataattgt atgccggttg ctttcaccac ttcattcttc ggagaaacac
     1441 caacagcaaa aattagcata tcagcagaaa ggacggagcc atctgataat actatttctc
     1501 gacctttatc acggatctca gtaactcttg tttctaaatg aacggctaat ccttctttca
     1561 gcaatttgtc ataaactaaa ttagcaattt ctggatcata agggaaagcg acttgtggca
     1621 attgatcgat taaagtcacg tctaagccgc gatgcttgaa attctcagct aattccagac
     1681 ccataacacc tgcaccaaga atgacgacat gttgtggatt tttttcttca aggaacgatt
     1741 tgattcgatc cgcatccgtc acactacgga ggacaaagcc gttttctgct tcaaaaactc
     1801 cgggaatatc cggataatct ggtctagcac cagaagagat gatcaactta tcgtaatctg
     1861 tttttatttc ttcatttgtg gataggtctt taactgttaa tcgcttagta gaaggatcga
     1921 ttgctgttac ttcgtgttta gtaaagacat cgatgttgtt ttttgttttc aatatttctg
     1981 gtgtacgttc gatcagcgag tcacggtcag tgatcacacc tcctaaataa taaggcaaag
     2041 cacaacttgc ataagaaata ttttctccgc gttcatagat aatgatttcg tgcgcttcat
     2101 tcaatcgacg gaaacgagtg gcaaatgaag gaccgccagc tacaccgcca atgacaacaa
     2161 ctttcataaa aacatctcct tttctacgtt gatcgtacta tgttatggta aaaaacagca
     2221 aataattgtg ccggaaaatt attgtttatt ttgaatagac agaaaatata gagaaataat
     2281 ttgtggataa aacctaaaaa tttttttcta ttttaaggat agataatact ttgaagggga
     2341 taaccctgta tattttttaa aagctgaaga aaaatgatgg atcgaatgaa atcctaatat
     2401 atctgcaatt tctgtatagg ttaattcatt ttctagcacg agacgttttg ctttttccat
     2461 ttttagttct ttaaaatagc taataacact ttttccattc acttttctaa aatgtttttt
     2521 taagctggct ggactgataa aaaaaatttg ggctaattgt tcaagcaaaa aattttctga
     2581 aagatgttct tctaaatatc gtatgattgg atcaactaat tcatctgaat aaagaatatg
     2641 ctttttttta ggaatgactt tctcatttga aggtattgtc aataaagcaa gttcctgttg
     2701 ataatgcctt ggtaaggaag acaattgaat tttttgcaga caataagtaa ctaataagga
     2761 aagcaaatga atgctcatct gttggcatag tatgaaaaaa gaattgattt cctgatcata
     2821 ggaaatagct ggcttactat gttttagata atcaattttg aactgttcat ttttcagaaa
     2881 agtaatgata gatgttattt cttgatctat agaaaaagat tgtcccgtaa tatgtgctaa
     2941 taattgctca tcaaaataaa actggataat gataaaagtt tgtgtttcct tttgagtaga
     3001 aaagatttgg acttcttgct gtttatcaat gaataaaagg gaaggattat ctagttctat
     3061 agatttatgt gcaaattcag catataaatt agcgctttca tttattagta gtcgaaaata
     3121 gggagcagca gataaatgaa gatgggtatc tatggaatag gttagtgttt ttttgacaag
     3181 attggaggat tggttgtttg ttaacaaaag aaccactttc ctttctcttt ttatataaaa
     3241 ag
//
LOCUS       DAZUJR010000160         3221 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.165, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000160 DAZUJR010000000
VERSION     DAZUJR010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3221
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.165"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            301..585
                     /locus_tag="ACG804_002851"
     CDS             301..585
                     /locus_tag="ACG804_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833712.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            588..1004
                     /locus_tag="ACG804_002852"
     CDS             588..1004
                     /locus_tag="ACG804_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833713.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
     gene            complement(1141..1860)
                     /locus_tag="ACG804_002853"
     CDS             complement(1141..1860)
                     /locus_tag="ACG804_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFS4833714.1"
                     /translation="MDEKTELTVKYQNELNLVPLKNFNAKQMDLFFALCARMKDRGLK
                     KVRFSFEELKELSDYKMTATKAFVGDLEKLYKDMLNLTYRTEDEDSIRYFVLFTGFEI
                     NKTKKFVEVSVNPDLEYIINGLTAEFSRFELSAFTSLRSTYAKTLFRLLMQYRSTGYY
                     VVRIEEFRSLMDIPEYYQMGNIDQKVLNPALRELKKYFNDLKVTKIKAKKGNKIAKLE
                     FTFSSLTSDLPKISLRNWLEE"
     gene            2544..2630
                     /locus_tag="ACG804_002854"
     CDS             2544..2630
                     /locus_tag="ACG804_002854"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HFS4833715.1"
                     /translation="MFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            complement(2932..>3221)
                     /locus_tag="ACG804_002855"
     CDS             complement(2932..>3221)
                     /locus_tag="ACG804_002855"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833716.1"
                     /translation="EYRRQRSDFISRKIVRLEKEKMEKFPYEYFQNLEKLEQAIQAIK
                     FDLTDEKLLEYKNMTPERKRSLEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
BASE COUNT         1074 a          599 c          503 g         1045 t
ORIGIN      
        1 aaaaaaaatg tcgtttgaaa aactaaataa atttttgatc gtgcattttt aaatttggtt
       61 atcgattaca cgtgcagcac tcccccccga attttaaaga gcataaggaa acgtgtaccc
      121 actttctaaa aaaagtgggt agataggctg tgcctatcac gtttctcaga aaaaaatttg
      181 atatcacttt ttcgccatcg tgggtagctt atgtatagca ttttggcaaa aaacagctat
      241 acaaatatag tatttgtatg gtatacataa attatacata attgcaaaag gagatttttt
      301 atggacattt tagttcggaa tattgatcca aagtttgttg caacaataga caaacgttgc
      361 caagaactca cgaataaaac aggagaaaaa tggagtcgaa ataaatatct aaaagtttta
      421 atcgaaagtg attttgaccg tcaacttacg acttacaaaa aagaccaatt cgatttattg
      481 ctcgataaat ttattgctat ccaaacagaa aatactcaaa tattaagcga gtatgtctac
      541 acaaataatc aaatcattga aatgcttatc ggaggaatga tataaccatg agaaaaactt
      601 ctgtccaaaa acatgttact ttgtacccta gtcatgttga cgttttagat tccatcatcg
      661 aaaaaaatcc agatatcaat aactactcgg aagccattcg ctttttatgt atgagttatg
      721 aacccgatac caacacgacc actaccagca atcaggcaaa actaaatgct atgggaaaag
      781 aaatttccat catgactgaa atcatcgcag aatttgctga tttatatcta aaagatacag
      841 gcgttcttat tggcacaaat tctaaagtat atcaagaagt gaaagaaaaa atcgaagcta
      901 aactaaatcc atcaaatcga aatcgaccaa agaatcatca aaaagaaacc agtcaaacag
      961 tcacttctag aaatttcgac ccaacaaatt ttctaaaacg ataaaaaaca gataggagtt
     1021 attcctatct gttttttatt tagaagcccc atacaatatg ctagaatgta ctagcaatct
     1081 tagtcggttg taagggactt gtctacttgc ttaatgtaag gggggcgagt tcttttttat
     1141 ttattcttct aaccagttac gcagagaaat ctttggcaaa tctgacgtta ggcttgaaaa
     1201 agtaaattct aatttggcga ttttattgcc cttttttgct tttatttttg tgactttaag
     1261 atcattgaag tattttttta gttctcgtaa tgcaggattt aatacttttt gatcaatgtt
     1321 acccatttga tagtattctg ggatatccat taagctccta aactcttcaa tacgaactac
     1381 ataataacca gtagaacggt actgcataag cagtcggaat agagtttttg catacgtaga
     1441 acgcaacgac gtgaaagcag ataattcaaa tctactaaat tcagctgtta aaccattaat
     1501 aatatattct aggtccggat taacactgac ttcaacaaac ttttttgttt tattgatttc
     1561 aaaaccagta aacaaaacaa agtagcgaat agaatcctca tcttcagtac ggtaagtaag
     1621 attaagcata tctttataga gcttttctaa atcaccgaca aaggcttttg tagcagtcat
     1681 cttataatca cttaactctt ttaattcctc gaaagaaaat ctaacttttt tcaaaccacg
     1741 atctttcata cgagcgcata atgcaaaaaa taaatccatc tgcttagcat tgaaattttt
     1801 cagcggtact aaattcaatt cattttgata tttgactgtt aattccgttt tttcatccat
     1861 tcctttcttc cccccttaca aataaataat aacctttaac aaccaactcg taaataggtt
     1921 ggttgttatt atacaaaagg atattagtac tcagataaaa agttgttagt actcagataa
     1981 aaagttgtta gtactcagat aaaaagttgt tagtactcag ataaaaagtt gttagtactc
     2041 agataaaaag ttgttagtac ccttctgtat ccgttgggag agtaaggctc aactgccccc
     2101 taaaaagggt tctaaaaaat ctttaaaaaa taaataaaat aaacgcgcgc gcgcgagcaa
     2161 aatttcccgc caaaaaatca cccacttttt aaaataaaca ggttcgcgca tgatattaaa
     2221 ctgccaatct agctccctat ggtcgctgta agaaggagtg atcgctacgc tctcacattt
     2281 tacttgcagc agtcgccttt aggctccttc gccaaaaata attcattagg gactcctttg
     2341 tggcgtcctg agagctcgtc taagccgttc taagacaaga ttcgataaaa actatgtcct
     2401 tcgttctaaa gcgccttaca ggcggtcagg gcaagcccta acaaccccaa ggcaataaaa
     2461 aacttaggct tatttttgct tttttattgt ataattgatt gtcgcctatc cgacagtctt
     2521 gcgactggaa ggaggtgtgt ttcgtgttca ctaactttat ttgctccctt cttgttgggc
     2581 ttttaagcgc tttgttcagt tactggttga ataaccgaaa caagaagtaa aacttaatta
     2641 aggcgactca gcccacaaaa aaagccccag agaatccgac ctctctgggg ctttcgtgtg
     2701 tttcgtgttc acttatttgc aatcaaatta taacagaaat aaatatttat ttcaaaaata
     2761 tcctacaaaa gtctaaaatc cgtaattatt tcttatatgc aacatttaca aataaagtcg
     2821 ctctgagagc tcgtattttt cgatttaaga cgttttattt agtttttggt gtatttcatt
     2881 ggtccaagct aaaaaactct tagaagcgat tttagagcca tttaaaccca cttaattata
     2941 ttctccatga aattcgctcc atgcgtcaaa agctgcgtct gaaattccgc cgtcttcgtt
     3001 cactagttgc attaattttt ccaacgatcg ttttctttcg ggtgtcatat ttttatattc
     3061 caacaatttt tcgtctgtta aatcgaactt gattgcttga attgcttgct ctaatttttc
     3121 taagttttga aaatattcgt aaggaaattt ttccattttt tctttctcca gtctcacaat
     3181 ttttctagaa ataaaatcac ttctttgccg tctatactct c
//
LOCUS       DAZUJR010000161         3181 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.166, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000161 DAZUJR010000000
VERSION     DAZUJR010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3181
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.166"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(42..1337)
                     /gene="purB"
                     /locus_tag="ACG804_002856"
     CDS             complement(42..1337)
                     /gene="purB"
                     /locus_tag="ACG804_002856"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HFS4833717.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(1350..2474)
                     /gene="purK"
                     /locus_tag="ACG804_002857"
     CDS             complement(1350..2474)
                     /gene="purK"
                     /locus_tag="ACG804_002857"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HFS4833718.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            complement(2467..2955)
                     /gene="purE"
                     /locus_tag="ACG804_002858"
     CDS             complement(2467..2955)
                     /gene="purE"
                     /locus_tag="ACG804_002858"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HFS4833719.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
BASE COUNT          854 a          751 c          562 g         1014 t
ORIGIN      
        1 ttgctattct attttaattg aattttgcaa ctcactcttc tttattccaa acctactcgt
       61 ttgaatatca cgtcaacgtt tttcaaatga tgatgataat caaaggcatc gtctatttct
      121 tctttagata ataccgatgt gatggttgga tcttcttcta acagcgggcg gaactgcact
      181 tggttgtccc aagcgtacgc agtttttggc tgaacaagat cataagcttc ttctcttgtc
      241 attcccttat cgatcaattt cagcataacg cgctggctat aaatcaaacc aaatgttgca
      301 gacatattcc gcttcatgtt ttcaggaaag accgttagat ttttaacgat attgccaaaa
      361 cgatttaaca tgtaattcaa taaaatcgtg gtatcaggca agatgattcg ttctgctgaa
      421 gaatgagaaa tatctctttc atgccataat gtgacatttt cataggcagt gaccatgtgt
      481 ccgcgcacca ctctggctag accagccata ttttctgaac cgatcggatt ccttttgtgc
      541 ggcatagcag aagaaccttt ttgacctttc gcaaaaaatt cttctacttc acgtgtttcg
      601 gatttttgca atccgcgtat ctctgttgca aaacgttcaa tacttgtagc aataagcgcc
      661 atcgctgaga aatattcagc atgtagatcc cgagggagaa cttgagtaga gatttcttgt
      721 ggacggatcc ccaattgttt acatacatac tcttcaataa atggcgggat atttgcgaac
      781 gttcccactg ctcctgagat ttttcctgct tctactcctt ttgccgcatg ttcaaatcgt
      841 tcgatgttcc gtttcatttc tgaataccat gtggcaagtt tcaatccaaa agtagttggt
      901 tcagcatgga caccgtgtgt ccgacccatc atcactgtat atttgtgttc ttttgctttt
      961 tcgccaatga tttccgtaaa acgtttcaag tcttcccgta aaatatcatt tgcttgcttg
     1021 atgagatagc cataagcagt atctacgaca tccgtacttg ttagaccata atggacccat
     1081 tttctttctt ctcccaatgt ttcagaaacc gctcgtgtaa acgcaacgac atcatggcgt
     1141 gttaattttt cgatttccaa gatccgatcg atatcaaatg atgcatgctc acgaattttt
     1201 ttcacatctt cttgcgggat ttcaccaagt tctgcccaag cttcatctgc taaaatctcg
     1261 acttcgagcc acgcacggta tttgttctct tccgtccaga tattccccat ttcagggcgt
     1321 gtataacgtt ctaacatgtt ttttctcctc taatcccaaa tattcgtttg tttgatttct
     1381 tccagcgttt gctggatgtc ttctgtcaag atagtgatat gtcccatctt gcgacctttt
     1441 tttgcttgtt tttttccata gaaatggaat tgccagtctg gcttattctc aatcaagcga
     1501 tagctttcca gcagttgttc tcccaaaaca ttgaccatta ctgcattgct tatcaaacgt
     1561 actttttctc ctaatggcca accacaaata cctcgaatat gggcatcgaa ctgactcata
     1621 gaacaagctt caatagaata atgtccagaa ttgtgaggac gaggagctaa ttcattcaca
     1681 tatagcccgc ctgtttttgt taaaaacatt tctaccccta aaacacctga aaggctcact
     1741 gcttctgcaa tcacacgggc aatacgctca gcctcctcga tcacatcctg atcaatcgcg
     1801 gctggagcaa tcgtttcatg aagaatattg ttgtggtgga tgttttccac gaccggaaaa
     1861 gtcgtgaaat ctccttgacc atttcctgcc accatgatcg aaatctcttt ttcaaacggg
     1921 atccatgctt ctaaaacaca ggttccttct cttaaaaggt ccatggcagg agctagatcc
     1981 gcccgacttt tcaaaacata ctgccccttg ccatcatagc cgcctcgagt ggttttcaaa
     2041 acacaaggat agccgatccc gtcaatcgca tcttggatat ccgtcggact gacgatcgtt
     2101 gcataaggag caatcacgat gttattcgtt tccaaaaaag atttttctaa caggcggtct
     2161 tgcgtaatcg caagcaagtc tgtcccttga ggaataaatg acatgggtaa aatcgcattt
     2221 aacgcctcta cactgacgtt ttcgaattca taggtaatga catctgttct tctggcaagc
     2281 tctttcagcg caaaggtgtc atcatagaca ctttcaatgt gccaatctgc aacttgtgcg
     2341 gctggacaat cgctcacagg atccagcaca cctactttaa agcccatttc ttttgcacta
     2401 atcgccatca tacgacctaa ttgaccgcca ccgacgatcc cgatcgttga accaggcaac
     2461 aaaggtttaa ccaagttgat cactactttc tataacagtt ttagccaaca ttgaacgtct
     2521 ttcagccaat ttagcctcca attctaaatc atacatggaa agcatctgta tcgcaagtag
     2581 tccagcatta attgctcccg cttttccgat tgctgtagta gctacaggta ctcctccagg
     2641 catttggaca atcgaaagaa gcgaatccaa accatttaat gttcgtgatt ggaccggtac
     2701 accgataacc ggcaaagttg tttttgatgc gaccataccc ggcagatgcg cggctccccc
     2761 tgctcctgca ataatgattt tgattccttt ttttcgagcg ttttgtgcat attcaaacat
     2821 caaatctggg gttcgatgag cagaaacgac ctttttttca taagacacac cgaattcatc
     2881 caatatttga catgcttctt tcattgtttc ccaatctgaa gtactcccca taatcacaga
     2941 gatttttgct gtcattgttt ttcctcccag tttttctaca ttcatatttt aacaatcact
     3001 ttttttgatg tcaaagaaat ttcgaatgtt aacaaagaaa aacattttat tgttcgtgtt
     3061 tattaaagat aaaaaaaagg aatgtgacaa aagttaggtc acattccttt ttatggataa
     3121 acggtgttct cctgccaact cctcggtcac aaggaacaat attcaacaaa catgagaagc
     3181 t
//
LOCUS       DAZUJR010000162         3079 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.167, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000162 DAZUJR010000000
VERSION     DAZUJR010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3079)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3079)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3079
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.167"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(296..910)
                     /locus_tag="ACG804_002859"
     CDS             complement(296..910)
                     /locus_tag="ACG804_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFS4833720.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(1516..1893)
                     /locus_tag="ACG804_002860"
     CDS             complement(1516..1893)
                     /locus_tag="ACG804_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833721.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(2193..3074)
                     /gene="galU"
                     /locus_tag="ACG804_002861"
     CDS             complement(2193..3074)
                     /gene="galU"
                     /locus_tag="ACG804_002861"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFS4833722.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
BASE COUNT          932 a          644 c          475 g         1028 t
ORIGIN      
        1 ttaagagaca agaaagaatc catatggatt ctttcttgtc tctttttcca ctacttttta
       61 tttttctgac actacatatt cttataactc atttctcata actgtgaaac aacttataaa
      121 aataacaaac tttaaacaaa acaagcttaa aatcaaagat gatccatctt aaaataacta
      181 aaacaaaaaa agtagtcgtt gttaatcctc attaataatc gttttctttt tttcaaacgc
      241 tccattttta tgtggaacat tattttttta aggaactttg tcaacatgtg gataactatt
      301 ttccacttgt gtcctggact agctgttttg ctgtaaaata caaaacttgc tgcagcaaaa
      361 agatcgttgc aagagaggct gttccgcaga tcgctggatc tagatttggc aaagtcaaga
      421 ctgcatcatg taaattggcg tggttgtcca aaaccaaatc agcaaattca aataatcgca
      481 aaccactgct atgttgcgat ttgatacttc gtgacaaatc aaatccagta acaatgatta
      541 atggatgacc attttctttg atccactgag ctagttcgat gattgccggg tttcttcctt
      601 cattcgaaag aagaagaaaa atgtcttctg atttgacaga aagctgatca ataattgcct
      661 gtcctgcacc ttctagcgtt tcatagacac ctccggctgg attttcaatc aatatacttg
      721 gtacaagatc cggggtttga tcccaaaatt caaatgctac accacttagt gtgcggctag
      781 catatatctg caatctacca ccttgattaa tttgtttcgc gatccaagtg ccagcttgaa
      841 gcatcagcgg ctcttctatc cttaatttct cttccaattg gtgataatag tcaaaataac
      901 ataaactcat ttatctctcc cgcctagcta tacttgacat gaatagaaac agctgcctaa
      961 tctaaggaag tacataaaaa aacagtagtt agacagtaac acatgtggtc tttgctgttt
     1021 caaacacaaa aaaggcattg aacgaatacg cccaatacct tgacatagca aataaaacaa
     1081 cgtgcagacc atggaaaata tctacatagg ggtagaattt tcaccctaga ttaggtacaa
     1141 taaattaggt cgatgcactg cattgactat ggcaaaatga tcggtcaggg tgtatgtgtg
     1201 tgactggtca ttccctgatt cttagcgcca actaagggtc agggagcctt tttttattca
     1261 gctgtttcta tctgaattta ttgtaagtaa tctcttatcc aagtgcaagc aagaaaatac
     1321 aaaaaaacat tggtatgatt tatatatata taaataacat aaaaaaagga atggcttatc
     1381 ccgatacaac aagcattcct ttaaaaaaga ttcttttata taagtgaaaa aagctttttt
     1441 ccaccaatta aataaatctc tcatctcaat agtttatcca ttattttatc tttttttgcg
     1501 tatacctact aaatattacc gtcttcttct cgttcttcta ctttgttcga gagaatctgt
     1561 actagaaaaa gtagttgtat gtctaccttt tctgcctatc cgagactttc ttttcatata
     1621 tgggatataa atgattagat acagtacagc aaaaaataaa gcaaatacgc aagcttccca
     1681 actacctaac gccaattcaa ccatcaaggt agcaacccca acggatgctg cataccagat
     1741 aaaaatcaga aacgtttctt tttttctgac catgcgaaac atgataaata gactaataag
     1801 caatagtggc aacacaaata tccaattgct tccttccatc agccacttga gtatatcaag
     1861 cagcgactgt gcaacagcga ctaattttcc catagtgaac acacaccttt ttttataatt
     1921 aaaaaattcg cctttttatt ctactatgaa tcttctggct tggctttcat ttctcttatg
     1981 taatcatttt cttttataca acttaaaaaa aaattaaacc attagcataa tattttctga
     2041 atctattcac gaaagtcttt ttctatcttt cgttttccac gactcaactg atctagagtc
     2101 aaaaaactaa aacgacagtt gcgcaaatga cgcacaagct gccgctttaa taacaaatag
     2161 cctttcattc tcagcaggcc acttatttcc agttaacttt ctgttcttag ctttttactc
     2221 aactggataa tatatgcact taatgaagtc ccaatttccg aatgttgaag tccatattca
     2281 atatttgtct tcatatatcc taacttatcg cctacgtcgt atctttttcc tttaaactct
     2341 ctcgcataga ccgcctctgt ctggttaaga gtctgaagtg catccgttag ctgtatctcg
     2401 tttcctgctc ctggttcttg agtttctaat atctcaaata ttttaggagt cagtagataa
     2461 cgtccgataa tggctaaatt acttggtgct tttcccattt caggtttttc tacaaaccct
     2521 tttactctgc aacgaccctt ttcgctatct gttttaggat caataattcc gtatttagat
     2581 gtttcatttt ctggtacacg catgacggca acagcggaag cttgtgtttc ttcataatcc
     2641 atcatcaatt gttgagtcaa tgggatatca tctttcatca aatcatcccc cagcatgacg
     2701 acaaacggtt catttcctat aaatgctttt gcttgaagca cggcatcccc cagtcctctt
     2761 ggatgagatt gacggatgaa gtgaagattg acttgagtcg tttcttcaac taaagcgagt
     2821 aattctgttt tttccttttc ccgcaaattg ttttccaatt cgatatttgc atcaaagtga
     2881 tcttcaatgg gtcttttttc ttttcccgtt acgatcaaga tgtcttcgat tcccgaatcc
     2941 aatgcttctt ccacaataaa ctggatcgtt ggtttatcca cgattggaag catttctttt
     3001 gccatggctt ttgttgccgg caaaaaacgt gttcctagcc cagcggcagg aatgactgct
     3061 tttttgacct tcacttgct
//
LOCUS       DAZUJR010000163         2956 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.168, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000163 DAZUJR010000000
VERSION     DAZUJR010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2956
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.168"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            90..407
                     /locus_tag="ACG804_002862"
     CDS             90..407
                     /locus_tag="ACG804_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HFS4833723.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNSSIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(498..863)
                     /locus_tag="ACG804_002863"
     CDS             complement(498..863)
                     /locus_tag="ACG804_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833724.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1071..1553
                     /locus_tag="ACG804_002864"
     CDS             1071..1553
                     /locus_tag="ACG804_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833725.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSTFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            1750..2640
                     /locus_tag="ACG804_002865"
     CDS             1750..2640
                     /locus_tag="ACG804_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042301 - phosphate ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HFS4833726.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
BASE COUNT         1010 a          460 c          566 g          920 t
ORIGIN      
        1 tttttaaaac atcacaagga aaaacttaac tatggtatta tctaaacata attttttcgg
       61 tatttaatat ttaattagga ggtaatattt tgctttttta tagtaatttt atcttaatag
      121 tagcgatatt attacttctg aatatatgga tttttgatag gagtagaaat tcaagtatag
      181 gttttagaac taaacgaagt ttgtcttcta aaaaaaattg ggtatactca caaactattt
      241 tttatggagg aattgtttta attagtttac tttcttcaac actttattct ttgaatatta
      301 tagatgtttc cacctcaaat tcaatatcta ttattggaat cattattgct gcaattatta
      361 cacaactgtt tttagtgttt ggagagaaga aaagaagtaa aaaatagaaa aactagtgat
      421 agttttggtg atataagaaa aacatatatg tataaaaaga agaaagtagc ttctctttgt
      481 acatatatgg tttgttttta tggatgccga gcttttttat aagataaggc taccgcccat
      541 aacgacccaa ggatttgtgg aactaagtaa atacctgcaa gaagcaagat cagctgggtc
      601 ggttttaaag gatgatagaa gtaacgccat tcagtaaaat tggcgcaaaa taaataggaa
      661 gtgacagtag atataatatt ggcaatgaat aaagatataa tacgcctgtt cctttgaaaa
      721 taatatccag caaaaagaga taaaaatatc aatgtgatga acccgcttac ggaatgataa
      781 cgaaaatcaa gcagtaaggc gaaatgcaca taaggaacaa aagataaaag caacggaagg
      841 tttttccagc aagtttttat catctttcat caccacctaa caagtgttat tattttgtta
      901 gttttattgt aaattgaatc ctgcaataat caattacttt ttcattattt ctagattaaa
      961 tgaataaact ctcatgccat tatctctaaa aaaaaagttt ttccccctaa tttttttaga
     1021 tagaaaattg tatagtatga tgagagaaaa agtagtttgg gggaacgtta atgagaagaa
     1081 aagcagtaat cgatcggctt tatttatttt tttggttttt tcctatcgtt ttgctacctt
     1141 ttacatgggt aaatgctgtt gtacaaggtg cggagatatt aggcctgatc caaggaagcg
     1201 gatttgtggt ttctaggaat tttccagctt tgattgtttt ctatttagtg ataagtgtag
     1261 gtctcttatt accaaaatct ctgatcaatc actacaattg gcagctgctt tacttttctt
     1321 gcttattagt atttacatct acgttttctt tgctgcctcg cttgattatc ggccctaatg
     1381 gtttgagcga gagtggattg aaggatttag cttattcctc catgtatttc ttgacgatca
     1441 aaccatggtt ctatttagta attgcctcat ttattcttgc aacatttttt tacttctgga
     1501 cagaaatcag gataaaaagt gaacgatctg tatctataaa aaataactat tgatggtgga
     1561 tcatcagtaa aaaaacatat gagctgcgta aaatgcatgt ttctcatatg ctttttttat
     1621 tattatgtaa agaatgcgaa aaacgtttac atgattttta cataacttaa ctatattttt
     1681 acagcaacca tacgagggat ttacagtcga ctgataaact ttagttgtaa ataagaaagg
     1741 agcaataaaa tgaaaaaagt attgtttact ctaggtatga tgggaattct tttagccgga
     1801 tgcggctcag gatcaggaaa tacagatggc tctgccacac aaaataattc aagtgactca
     1861 aatgaacaag taaaaatcgt tgcggtaggt tcgacagcat tacagccgtt agtcgatgca
     1921 gcacaagaaa gctttgtaca agaaaatcca aattatcaaa tctctgtaca aggaggagga
     1981 agcggaactg gtttgagcca agtcgaagct ggagcagtta ctatcggaaa ctctgatgta
     2041 tttgcagaag aaagagacgg agttgatgct tcaaaattag tggatcataa agtagcagtg
     2101 gtcgggatgg caccaatcgt caataaagat acagatgtca aagatatcac caaacaggaa
     2161 ttgattgata tctttacagg aaaaatcact aactggaagg aagttggcgg gaaagatcaa
     2221 aaaatcaacg tcgtgaaccg tgcaaacggc agcggtaccc gcgcgacatt cgaaaaatgg
     2281 ggactggatg gtgctacccc tgtgcagtcc caagaacaag attcatcagg aacagttcgg
     2341 cagctggtaa gtcaaacacc aggagcaatc agctatttag ctttctcata tctcgatgat
     2401 tccacacaag cactaagtat cgacggtgta gaaccaaaag aagagaatgt agcagataac
     2461 agctggggaa tctggtcata tgaacatatg tacacgaacg gaaaaccttc ccctgaagtc
     2521 caaaaattct tagactacat gatgacagaa gaaatccaag aaggacctgt caaagaattg
     2581 ggctatttac caatcacaat gatggaagta gaacgtgatc acgaaggaaa tatcaaataa
     2641 ctagcagata aacatgccac ggtagtcgtt actattaagg aaaaatcaac tatgtttccc
     2701 cacatataca tttttccttt aattgtgaaa aatagttcct catattttgc cgttttttga
     2761 gctaataccg agggtcagct gattgaacac cgtttattcg aaaaaaagag ctacgacata
     2821 gaactgtcgt aacttttttt ggctcttcgt caaatcgtgt tggtgaagac aaatttgaat
     2881 aaaacttaga ccgatatgcg gcgcgttctg tgcgccgcat atttttttag ttttcaaaga
     2941 tcagaccttg ttgtaa
//
LOCUS       DAZUJR010000164         2944 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.169, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000164 DAZUJR010000000
VERSION     DAZUJR010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2944
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.169"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            49..273
                     /locus_tag="ACG804_002866"
     CDS             49..273
                     /locus_tag="ACG804_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HFS4833727.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            270..1289
                     /locus_tag="ACG804_002867"
     CDS             270..1289
                     /locus_tag="ACG804_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFS4833728.1"
                     /translation="MKKKITITAMSLLTALFLLPINTFAYTINNEFNLGPNEGSSQVA
                     NNQYILLHETANETATGRNEAQYMKRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSDDKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVKADGIY
                     RPDVNQAYNTLGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPQR"
     gene            1593..2000
                     /locus_tag="ACG804_002868"
     CDS             1593..2000
                     /locus_tag="ACG804_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833729.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            2014..2415
                     /locus_tag="ACG804_002869"
     CDS             2014..2415
                     /locus_tag="ACG804_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833730.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            2417..2788
                     /locus_tag="ACG804_002870"
     CDS             2417..2788
                     /locus_tag="ACG804_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833731.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
BASE COUNT         1056 a          451 c          557 g          880 t
ORIGIN      
        1 ggtagaacac acgcaacaaa ttaaaacttt atttagggag agaagaaaat gaataataaa
       61 acgttcgaag tactaaaatg gttcgcactg gtaattattc ccgcactagc tactttcgtg
      121 gggttagttg gtaaagcgct caattggcag tacacagata tctgtgttgt catcattact
      181 ggttttggcg cgtttttagg gagtgtgttg ggtgtatcaa atcgaaccta caaaatgttc
      241 tcggctgaaa gcgaagaagg aggaaacaaa tgaaaaagaa aattactatt actgcgatga
      301 gcctgttaac ggctcttttt ttattaccca ttaatacgtt tgcttatacg atcaacaatg
      361 aatttaattt gggcccaaac gaaggtagct ctcaagtagc aaataatcag tacattttac
      421 tgcatgagac agctaacgaa acagcaacag ggcgcaatga agcgcagtat atgaaacgtt
      481 catggactag tgcttacact gcttatattg tgggagacgg cggaattgtt taccaagtcg
      541 gacaacctgg ttatgtacag tacggtgctg gttcgtatgc taatgctaac agtcccgtgc
      601 agattgagtt acaacacaca catgataaag caacgtttga gaaaaactac aaggcatacg
      661 ttgaattagc tagagattca gcaatgaaat atggtattcc acttacacta gacacaccgt
      721 ataatcaacc agggatcaaa tcgcatttat gggtaacaca aaatatttgg ggcgatcata
      781 cagatcctta cggttatctt tctgaaatgg gcgtaagtaa agaaaaatta gcctatgatt
      841 tggctcatgg atttaccgat gaaaatccga caacttcaga tgataaacca gtcattgatc
      901 caactcgagc aggtgctgca aatcctaccc tgacagatgg aacaaattac gcccacattg
      961 atcagttcgg agaaatcgaa aacgcaaact tacatgtggc tggttggcac atcgctaact
     1021 ataaatacga gtatatcttc attatggatt acaatactgg gaaagaatta gctcgagtaa
     1081 aagctgatgg aatatataga ccagatgtaa atcaagctta taatacttta ggaaatgttg
     1141 gctatcatgt atcttttaac atgcgcaact tccctaataa gaaagtctat gtaatgatgc
     1201 gggcaacgaa tgatccagaa gggaacacta aaggcggagc acaagatttt catgataaac
     1261 gctggtattt aaatattccg caacgataaa aatagcccct catttttgag gggaagtaca
     1321 tatagttgtt gatatagttg ctaatattgt tagctaattt gttagtaaaa ctgtatacga
     1381 atttagatag taaaaaaaca gtttgttcct tatatagagg cacttttact actgattaaa
     1441 tgtcagatat gcttacaaat atacttataa atatgcttac aaaattagct aatatttccg
     1501 ttgacaaagc tttgttacta ttgttaaact aaattgacta gcaaaagtga aacataaatt
     1561 tattaaataa atgtaaaaat taggagaaat caatgtctta tagagtacaa ttaataattt
     1621 cagaagatgt agaaagtcag caatttggca ctaatgttat taataaagta attaatccag
     1681 ctctttctat taatgcgcct ttaattccta ctgctttatc attttctgta acagctgtgg
     1741 tgtctgagat agaggataca gaaaagataa aaatagtaga aattgaagtt ttaaacaaga
     1801 atgaaaaaca aattttttct acgggtgaag tatcggtaag cttgcctcct caagttaacg
     1861 atataaactt taatataaac gccagaaatg tcttggttga agaagcagga gagcattatg
     1921 ctgttgttaa atttaatgga actgagattg gaaggcaaat ctttgatatc aaggtcaaca
     1981 aaccagtgga aaaaaattaa ggagacgata cggatgcttg atatagtacc atcaaataca
     2041 catcggagtg gtagcttaat aaattttgct gcgatttttg cttgcgcatc ggtaattcta
     2101 gcatctccag ttgttgtgga tgcaagttct actccgaaaa ctaaaaatga taatcaactt
     2161 gtaattacta caaaaaatga gattaacaca atttcaagta atgatggcaa aatttttgat
     2221 gtgataaata cggttttaaa aagaaaagct gaaatcaata taaaatatga tgaagattta
     2281 aacttgtatt tctttgttat caaaacaaca tctgaattgt tttcctcaga ttacgatgtt
     2341 ttggatactc tcgataatgt attatctgac tataaatata tggggaaatc tgtagtagca
     2401 actttggggg aataaaatgt ttgactttaa tgaatattta tctatttcca aacaaattga
     2461 atcagatgat aaatataatt ctaaagaatc ttatagaaga actgctgttt caagagcata
     2521 ctacagtgct tttaaaaaat ctgatgagta tttgaaagaa aattatgata ttatttataa
     2581 tggaagtagc ggaaaaggaa gccaccaaac cgtttggaat ttgttttcaa cagttaagga
     2641 attgaatacc ttaggaatac ataatagtgg gtatagaatg ttagagaaaa gaaaatgtgc
     2701 tgactatatt cctaatgaaa ccattacgaa aacagatatg gcgctgatga atcgagaagc
     2761 agaaaaaata ataaacaaac tcacctaatg aatttcaagc gagtttgttt gttatttttt
     2821 tatttaatct ttgtatcttt ctggatcaac gaaagtatac tttatatagt cataacgccg
     2881 atgatcgcta cgtgcgtccg gcacgtcagt cacgatatca aacaaaaagt atacatcctt
     2941 cttc
//
LOCUS       DAZUJR010000165         2939 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.170, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000165 DAZUJR010000000
VERSION     DAZUJR010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2939
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.170"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(366..1658)
                     /locus_tag="ACG804_002871"
     CDS             complement(366..1658)
                     /locus_tag="ACG804_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HFS4833732.1"
                     /translation="MARKKRNPDAEKLAESILNAYQPESVDDMQDALKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKEHDNRRNGYGTKTLKTSFGEVAIDVPRDREASFEPELIP
                     KRKRDVSDIEGKVLSMYARGMSQRDIAATVEAIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKARGVEDVFFISMDGVSGLEEGAKAIFPSVIVQRCIVHLVRNALRYIPSK
                     DYKEVCRDMKKFYGASSLNAAHAAFDSFQNRWSHYSGAVDVWKRNFAHVEQLFDYGSA
                     IRKIMYTTNAVESVHSSFRKVTKKGAFSNENALLKLLYLRTKELHAKWSGGRIQNWAM
                     VLNQLMINETFSSRMKSMRFTFRNNGRFIQLCVRSKFI"
     gene            complement(1932..2192)
                     /locus_tag="ACG804_002872"
     CDS             complement(1932..2192)
                     /locus_tag="ACG804_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833733.1"
                     /translation="MKKIDLINMIGMLIGILVNIVIFTDWLGVLFSNLIPILIIGICG
                     IILSILELFESRNTMNRIFACIILIVNLLPMVYFTFLYFALG"
     gene            2443..>2939
                     /locus_tag="ACG804_002873"
     CDS             2443..>2939
                     /locus_tag="ACG804_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HFS4833734.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDAT"
BASE COUNT         1007 a          547 c          453 g          932 t
ORIGIN      
        1 gtatgggcta ctctgtgata cttattagcc attaaactat tttacccaca tagcatatat
       61 tttgaaatcg ttcattccgt aaattcaact aaatatgcct aaaaaaataa aaaatctaag
      121 atagaataag atttattcag tcttagatgg atttatagca actttttcgt aacaacttta
      181 aaaaatacga aaagaaagag ctgttttact ctgactacgt tgctaaattg tcgtttaatc
      241 attcatttaa accaaatctt tttttataga attcgtttta atcctcctga atccaaaaac
      301 tatgaaaacc gtaattaaat agttaagagt ttttaaccac cataattctc tcggctattt
      361 tgaaatcaga taaattttga tcggacacat agttgaataa acctaccgtt gttacggaag
      421 gtaaatcgca tacttttcat tctagaggag aaggtctcgt tgatcattaa ctgattaagc
      481 accatagccc agttttgaat tcgaccacct gaccacttcg cgtgtaattc tttcgtgcgt
      541 aaataaagta gttttaggag tgcattctca ttagagaacg ctcctttttt tgtgactttt
      601 ctgaagctgg agtggacact ttcaaccgca ttggtagtgt acataatttt tcgaatggca
      661 ctaccataat caaatagttg ttcaacatgt gcaaagttcc gtttccagac atctacagca
      721 ccagaataat gagaccaccg attttgaaaa ctgtcaaaag cagcatgtgc agcgtttaga
      781 gaagaagcac cgtagaactt tttcatatct cggcagactt ccttatagtc cttacttgga
      841 atatagcgca atgcatttcg aacaagatga acaatacagc gctgaacaat taccgatgga
      901 aagatcgctt ttgcgccttc ttcgaggcca gaaacaccgt ccatcgaaat gaaaaagaca
      961 tcttcgacac cacgtgcttt cagttcatca aatacttgca tccagcgatt tttagattct
     1021 gtttgattta accataatcc taaaatctcc ttatttcctt tgagatcata gccaagaatg
     1081 gtgtatacag catattcttt ggcttcataa ttttctcgta aagtaacata catacaatca
     1141 acgaatagaa aggcataaca ctttgctagg gggcgggctt gccattcttc caattcagga
     1201 aggacagcgt cagtgatatc tgaaatcatt tcatgggaaa tatcaaagcc ataaatagct
     1261 tcgacggttg cggcaatatc tcgttgactc attcctcgtg catacatgga aagaaccttc
     1321 ccttcgatgt cggagacatc tcgttttctc ttaggaatta actctggttc aaaggaagct
     1381 tcccggtctc taggaacatc aatagctact tcaccaaaac tggttttaag cgttttagtt
     1441 ccatagccat ttcgacggtt atcgtgttcc ttaggctctt tagaatgggc atcataacct
     1501 aaatgattat tcaattctcc ttgaagcatt ttttcaaaaa ggggcccaaa cacatctttc
     1561 aaagcatctt gcatgtcatc gacagattca ggttgatagg cattcagaat ggattcagct
     1621 aacttttcgg catcaggatt tcttttcttt ctagccatcg tgtaatcacc tcttgatctt
     1681 attgtagaaa aagaaaaacc gcgaagcaac cacctgccta ggattaatgg ttacttacac
     1741 ggtttatatt acactctcat cattaaaaaa gtatctttcg atattactaa acaatgaaat
     1801 tatctatttg aaatttaaat ctgataatat attgagtgtt ccaatgaggg ctttgatcct
     1861 attatccata tctttttcag ttttaatatt gatacacatt ataagaaaaa gaaacttttg
     1921 gttaatttat ttcatcccag tgcaaaatat aaaaaagtaa aatagaccat aggcaataga
     1981 ttaacaatta atataataca agcaaatatt ctattcattg tatttctgct ttcaaaaagt
     2041 tctaatattg aaagtataat tccacaaatg cctataataa gtatgggaat aagattagaa
     2101 aataacaccc cgagccaatc tgtgaaaatt actatattta ctaatatccc tattaacata
     2161 cctatcatat ttattaaatc aatttttttc attagatatt tctcctttat taaatctgaa
     2221 gtacttatat taaaataatt ctaaactatt tacctcaaaa agtgcaataa attatttctg
     2281 aacaataaaa tgatagtcaa aacaaaaaaa tattgttaat cgttcagagc catccgagag
     2341 tgtaaaatat tttgtgtaaa tgaaaaaatc catacaaaaa aggaagtccc ttctgtagaa
     2401 taaagttaac gacaaccaat tcacagaaaa gaggacttcc ctatgaatga ttttactaca
     2461 gaaattgtgc aaactctagt cactaaaggc gatttaaatg aattattccg ttcgcactta
     2521 gaaaaagcga taaacacact cctacggact gaattaacgg cttttttaga ttacgaaaaa
     2581 tatgatcgca ctggttttaa ttcaggtaat tcgagaaacg gttcttactt tcgatcaatc
     2641 aaaaccgaat atggtgaatt aacattggaa atacctagag atcgtaatgg tgagtttaaa
     2701 caacaaactt taccagccta caaaagaaca aacgatacat tggaaaccac tattatccat
     2761 ttattcgaaa aaggtgttac gatgtctgaa attgctgatt tgatcgaaaa aatgtacggt
     2821 catcactata ctccacaaac catgtccaac atgactaaag ttctgactga agaagtaaat
     2881 gcctttaaat ccagagcctt aaatgataag tatgtcgcta tttttatgga cgctactta
//
LOCUS       DAZUJR010000166         2796 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.171, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000166 DAZUJR010000000
VERSION     DAZUJR010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2796
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.171"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            700..2610
                     /gene="ltrA"
                     /locus_tag="ACG804_002874"
     CDS             700..2610
                     /gene="ltrA"
                     /locus_tag="ACG804_002874"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFS4833735.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
BASE COUNT         1085 a          435 c          569 g          707 t
ORIGIN      
        1 aaaagctaag gcactaataa aagaacgaaa aagtttggtt attaggagaa ctgataatct
       61 gacaggtgga atgatgaagt aacgctctga aacgcctgcc ctgagcctcc gacaagcatt
      121 gtatgaggaa actcagaatg tttgaagctc ggtaaagacg gctgaaagat accgtaatag
      181 ttgatgaaca tatatcttct atcgaaaact atccagaggt gggtagcgta tccaacaggt
      241 cgggggtcta taaaatatct atggttagaa tgttctataa ggaactgacg aaacagcgaa
      301 tgtacgggtc taaatttgaa ctttgtagaa atgcaaaggt acgagaaatc gtagctggtg
      361 tggcaaagta agaatatagg ttatgaaatg ccatataacg ttacaggcgg tatcaagcca
      421 gcaggcttat agctagtgac ctaaggatat atatgtatag ataagattat cggaacgagg
      481 aaaggtattg ggttctcatc aagagaataa actgacgaag aacaataagc agttgaacta
      541 atgctgaaaa gcagagggcg aacctaagaa attcttgtaa tgagaatgga ggaatgccct
      601 caagtcgtgt atatattaga aaagtattat gttgtttcaa taaggattac gagtaagata
      661 aaaaagctca ctcaatttca agtaaaggag tgaagcctta tgcctaaaaa taaaaatgaa
      721 acattgtgtg tagaagattt aagacacgct gaatattacg aaatgcaaaa cacctttgat
      781 gatttatatg ccaaaagtaa gaatggagat attttcactc atcttatgga tattatccta
      841 tcgagagaaa atatattact ggcatatcga aatatcaaag caaatgcagg cagtaaaaca
      901 gcaggaacag acggtacaat aattaaagat attggcaaat tgccagcaga aacagttgtc
      961 aaaaaagtaa gatacattgt tgcaggcagt ccacatgggt atcgacctaa gccagtgagg
     1021 cgaaaagaaa taccaaaacc aaatggtaaa accagacctc taggtattcc ttgtatgtgg
     1081 gacaggctta tacaacaatg tataaaacaa gtattagaac caatctgcga agctaaattt
     1141 agtgaaaaca gctatggttt tagacctaat aggtcagttg aaaatgcaat aaaagcaacc
     1201 tataaccgcc tacaaatcag ccagctacat tatgtgattg aatttgatat taagggtttc
     1261 tttgacaacg tgaaccattc caagctgata aaacagatat gggctatggg aatacgggac
     1321 aagcacttga tattcatttt aaaaaggata ttaaaagctc caatcaaaat gactaacggt
     1381 acaataacat atccagagaa aggaactccg caagggggaa taatatcccc actactagca
     1441 aacattgttc ttaatgagtt agaccattgg gtagaaagcc aatggcagga aaatcctgtt
     1501 acaaaaaact atgtggttca tatcaataaa agcggtagcc catgtaaaag caacgcttac
     1561 aaagaaatga agaaaacaaa gttaaaggaa atgtatatgg ttcgttatgc agatgatttt
     1621 agagttttct gccgctacaa ggaaagtgct gaaaaagcca aaatagcaat cactcaatgg
     1681 attgaacaac gattaaaatt ggaagtatca caagaaaaaa caagaattgt aaatgttaga
     1741 aaaagatact ccgactttct tggtttcaag attaaaatga taccgagaag aaagaagtta
     1801 gttgttaaat cacatataag tgataaacaa ttcaaaaacc aaaaagacaa gctggtatca
     1861 caggcaaaga aaattgcttc tccctcaaaa gggaaaacgg aattagaaga aacaagactt
     1921 tataattcaa tggtattagg tatgcaaaat tattatcaga ttgcaacgaa tgtaaatctg
     1981 gattgtatga aactgaatag agctgtaatg gctatcttca ctaacagatt aggtacaaac
     2041 aaaaggggca gattgagaaa aacaggcaga caacttacga caaaggaggc aacaagatat
     2101 ggtaaatcta aaatgcttcg gtatgttgct ggcgagggcg aacctatttt ccctgttgga
     2161 tatatccaac acagaaaacc aatggcaaag gtgtatttag cgaattgcta cactctagag
     2221 ggaagaaaat ttatccacac caatctaagt gttgataaat tactgatgta ccagttaatg
     2281 aaattatctt tggaaaatcg cacaatagaa tacgcagaca atcgaatttc gctattttct
     2341 gctcaacatg gaaaatgtgc tataactctg gaagaatttc aacaagctaa tgaaatacat
     2401 tgtcatcata ttgtaccaac tggagctggt ggaaatgacg attataaaaa tcttattttg
     2461 gtaaaagagg cggtacaccg tctaatacac gctaaaacag aagaaacaat acaaaaatat
     2521 atagctctat tgaagctaaa taaagtccag ctcataagac taaataaata tagagtatta
     2581 gctggcaatc aagaattaaa cttgatatag gtctactaca taaatacttt tcaatataaa
     2641 cacgatggaa cgcggagtgc ggtgaaagtc gcacgctccg tgtgaatggg gggaaaagtt
     2701 tgagatattt ataatatcag gaacttacct atccatatat caatggtttt taaccaatgc
     2761 tcaatcttta gtcttactag cgattgtggt cattgg
//
LOCUS       DAZUJR010000167         2774 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.172, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000167 DAZUJR010000000
VERSION     DAZUJR010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2774)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2774)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2774
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.172"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            39..1517
                     /locus_tag="ACG804_002875"
     CDS             39..1517
                     /locus_tag="ACG804_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HFS4833736.1"
                     /translation="MKKLSQKRLAQIIIDSRKSLKMTQQQLAVATGINRALISRLESL
                     DFIPSIQQLESLAEVLNFEPTDLFINESNKSNRTKHQSKNIAVAGTGYVGLSIATLLA
                     QHNQVTAVDILPEKVKQINNKKSPIQDDYIEKYLAEKNLNLIATTDGAAAYREADFVV
                     IAAPTNYDSKQNYFDTSAVESVIKLVLEVNPKAIMVIKSTVPVGYTESIRKKYNTKNI
                     LFSPEFLRESKALYDNLYPSRIIVGTDQTDKTLREASHTFADLLQEGAIKKDIETLFM
                     GFTEAEAVKLFANTYLALRVSYFNELDTYAEMKGLNTQEIIHGVCLDPRIGTHYNNPS
                     FGYGGYCLPKDTKQLLTNYNDVPQNMISAIVDSNRTRKDFIADRVLELAGTYEANSSW
                     NAEKEKEVVIGVYRLTMKSNSDNFRQSSIQGVMKRIKAKGATIVIYEPTLENNTTFFG
                     SKVINNLDDFKNISHSIIANRYDSNLDDVKEKVYTRDLFQRD"
     gene            complement(1585..2676)
                     /locus_tag="ACG804_002876"
     CDS             complement(1585..2676)
                     /locus_tag="ACG804_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HFS4833737.1"
                     /translation="MLELNTSLSNRTILITGAAGFIGSNLVLELLRTQSSIKIIGIDN
                     MNDYYDVSIKNYRLSEIETEAKNHPGSTWNFIKGSIADKATIDFIFDNYKPSIVVNLA
                     AQAGVRYSITNPDMYIESNIIGFYNILEACRHSYDNGESGVEHLVYASSSSVYGTNKK
                     IPYSTEDKVDNQVSLYAATKKSNESMAHAYSKLYNIPSTGLRFFTVYGPAGRPDMAYF
                     GFTDKLRAGDNIQIFNYGNCKRDFTYIDDIVEGVKRVMQCAPEKIDGEDGLPIPPYHI
                     YNIGNNTPENLLDFVDILQQELIAAGVLPEDYDFESHTELVPMQPGDVPVTYADTSAL
                     ERDFEFKPSTSLRDGLRKFAQWYKSFYEV"
BASE COUNT          966 a          500 c          444 g          864 t
ORIGIN      
        1 ttgtttgtta ttattagcaa caaaaaaagg agtgcatcat gaaaaagtta tctcaaaaac
       61 gtttagctca aatcattatt gattctagaa aatctctgaa aatgacacaa caacaacttg
      121 cagtagctac tggtatcaac cgtgccttaa ttagtcgatt agaatctctc gattttatcc
      181 cgtcaataca acaattagaa tcattagcag aagttctaaa ttttgaacca acagatctat
      241 ttataaatga atcaaataaa tcaaacagaa caaaacatca gtcgaagaat attgctgtag
      301 ccggtactgg ttacgtaggt ctttccattg ctactcttct tgcccagcac aatcaggtaa
      361 cagcagtaga cattcttcct gaaaaagtaa aacaaattaa caataagaaa tctccaatac
      421 aagacgatta cattgaaaaa tatctagctg aaaaaaatct taatttaatt gcaacgactg
      481 atggtgcagc cgcctataga gaagccgatt ttgttgtcat tgctgctcca acaaattatg
      541 atagtaaaca aaattatttt gatacttctg ctgtagagtc agtaatcaaa ttggtgttag
      601 aagtcaatcc aaaggcaata atggtcatca agtcgacggt acccgtaggc tataccgaaa
      661 gtattcgtaa aaaatacaat actaaaaata ttctattcag cccagaattt ctcagagaat
      721 ctaaggcatt atatgacaat ctatatcctt cgcgaattat tgtcggcacg gaccaaactg
      781 acaaaacttt acgagaagcc tctcacactt ttgcagattt actccaagaa ggagcaatca
      841 aaaaagatat cgaaactctt ttcatgggat tcacagaagc tgaagcagtt aaattattcg
      901 ctaatactta ccttgcactt cgagtatctt acttcaatga gctggatact tatgcagaaa
      961 tgaaaggact aaatacacaa gaaatcattc acggggtttg cttagatcca agaattggca
     1021 cacattataa taatccatct tttggatatg gaggctattg tttaccgaaa gatacaaaac
     1081 aacttctcac taactataac gatgttcctc agaatatgat aagtgcaatt gtcgatagta
     1141 atcgtacaag aaaagacttt atagcagatc gagtgttaga acttgctggc acgtatgagg
     1201 ctaacagttc gtggaatgca gaaaaagaaa aagaggtagt cataggtgta taccgtctta
     1261 caatgaagag taattcagac aacttccgtc agtcatctat tcaaggagtt atgaagcgaa
     1321 ttaaagcaaa gggggcaact attgtaattt atgaaccaac acttgaaaat aacactacat
     1381 tttttggttc aaaagtaata aataatttag atgattttaa aaatatcagt cacagtatta
     1441 ttgctaatcg ttacgatagt aatcttgatg atgtaaaaga aaaagtatat accagagatt
     1501 tatttcaacg agattaaaaa ataacacctc agatttgtag tgtctgaggt gtttctataa
     1561 acttttataa gtaaaaaaat acaattatac ttcataaaaa gacttatacc actgcgcaaa
     1621 tttacgaagc ccgtcacgca aacttgtact tggtttaaat tcaaaatctc gttctaacgc
     1681 actagtatct gcataagtaa ctggcacatc tcctggttgc attggaacta gttcggtatg
     1741 agattcaaag tcgtaatctt ctggtagcac ccctgctgca attagctctt gttgtagaat
     1801 atctacaaaa tctagtaggt tttccggcgt attgttacca atattataaa tatgatatgg
     1861 tgggattggt agcccatctt ccccatcaat tttctctgga gcgcactgca taaccctctt
     1921 tactccttca acaatatcat ctatataggt aaagtcacgc ttgcaattcc cataattgaa
     1981 tatttggata ttatcaccag cacgaagttt atcagtaaaa ccaaaataag ccatatctgg
     2041 acgcccagca ggaccatata ctgtaaagaa acgtaaccct gtagacggaa tattgtaaag
     2101 tttagaatat gcatgtgcca ttgattcatt acttttctta gttgctgcat acaacgatac
     2161 ttgattgtct actttatcct ctgtagaata aggaattttc ttattagtac cataaacgga
     2221 agacgatgag gcatacacta aatgttccac accagattct ccattatcat atgaatgacg
     2281 acaagcttca agaatattat agaatcctat tatgttagat tcgatataca tatctggatt
     2341 agtaattgaa taacggactc ctgcctgagc tgctaaattc accacgatac ttggtttata
     2401 attatcaaag atgaaatcaa ttgttgcttt atcagcaata gaacctttga taaaattcca
     2461 agtagatcct ggatggttct ttgcctccgt ttctatctct gataatctat agttcttaat
     2521 agagacatca tagtaatcat tcatattgtc aatgccaatg atttttattg atgactgagt
     2581 acgtaataac tcaagaacca aatttgatcc aataaaaccg gctgcgccag ttattaatat
     2641 tgttctattt gataaggacg tgtttaattc cagcattttt tagcactcac tttctttttt
     2701 tcttatgaat acatatttgt tatatattaa aaaatcttat ttagacttat ctattgtcac
     2761 ttttatcatt ctaa
//
LOCUS       DAZUJR010000168         2628 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.173, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000168 DAZUJR010000000
VERSION     DAZUJR010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2628)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2628
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.173"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..541
                     /locus_tag="ACG804_002877"
     CDS             <1..541
                     /locus_tag="ACG804_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase"
                     /protein_id="HFS4833738.1"
                     /translation="VLQVFHPVVTELENIEKQILALINSMEQQSQPIICILPNSDAGS
                     EIIRKMYQKYLKTDIIYITNLEPEEYLTILKECKFMIGNSSSGIIEAASFKIPVINLG
                     TRQNGREQSKNIINANLNENEIETALNKIQDPQFIKSLKNVKNIYGDGNSSRRITKTL
                     NQILNDGEDIKWIQKQIAY"
     gene            514..1191
                     /locus_tag="ACG804_002878"
     CDS             514..1191
                     /locus_tag="ACG804_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HFS4833739.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            1142..2323
                     /locus_tag="ACG804_002879"
     CDS             1142..2323
                     /locus_tag="ACG804_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HFS4833740.1"
                     /translation="MAIQLKLRKKELILNSRILLSSPHMGGTEEKYVAKAFKDNWIAP
                     LGENVDKFEESITKYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATV
                     NPILYQGAVPVFIDSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYER
                     ILAIANQFNVPVIEDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSD
                     KKYVEHSRFLATQARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIF
                     NRYKEAFSGIDRIEMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRA
                     LWKPLHLQPVFQGVKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIF
                     K"
     gene            2336..>2628
                     /locus_tag="ACG804_002880"
     CDS             2336..>2628
                     /locus_tag="ACG804_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFS4833741.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNE"
BASE COUNT          978 a          344 c          511 g          795 t
ORIGIN      
        1 cgttttgcaa gtatttcatc cagttgtaac cgaactagaa aatatagaaa aacaaatttt
       61 agctttgatc aattcaatgg aacaacaatc tcaaccaatt atttgcattt tacctaatag
      121 tgatgctggt agcgaaatta tcagaaaaat gtaccagaaa tatttaaaaa cggatattat
      181 ttatattacg aatttagagc cggaggaata cctgactata ttaaaagagt gcaaatttat
      241 gatcggaaat tcttcttctg ggataattga agctgcatca ttcaaaatac cagtaataaa
      301 tttaggaacc agacaaaatg gacgagaaca atctaaaaat attataaatg caaatctaaa
      361 tgaaaatgaa attgaaactg ctttgaataa aatacaagat cctcagttta taaaaagctt
      421 gaaaaatgtt aagaacatct acggtgacgg caacagttct agaagaataa caaaaacatt
      481 gaatcaaata ttgaatgatg gggaagatat taagtggatt caaaaacaaa tagcttatta
      541 aaatatacta gtgatccata cattattatt ggggctggcg gacacgcaaa agtcattatt
      601 gaaaccttaa gattagaaaa taagttaata tatggatttt ttgatgataa gcaaaataaa
      661 atgcaagatc tgaaatatct tgggaaaata aacgaattga atagctgggc ggatagcaaa
      721 aaaaaaatct ataaatttat tgtagctatt ggtgactgtg tagtaagaaa aaagattata
      781 aaaaaattga atatgccaag tgagcaatat ggaatagctg ttcatccaag tgctatagtg
      841 gcaaaagaaa tttcaattgg ttatggaact gttatttttg cgaatgctgt aattaaccca
      901 gatgctgtaa ttggagagca tgctataata aacacaggta gcattgttga gcatgattgt
      961 agaattaata actatgttca tttatctcca ggtgtatgct tagcgggtgg agtacatgta
     1021 ggtgtaggaa ctcaaatagg aattggttct caatgtatcc agatgaagaa aattggatct
     1081 tggtgtatga taggcgcagg gagcactatt gttaaggata ttccctcaca ttccttagct
     1141 tatggcaatc cagctaaaat taagaaagaa ggaattaatt ttgaattcta gaattttatt
     1201 atcaagtcct catatgggag gaacagaaga aaaatatgtt gctaaggctt ttaaagataa
     1261 ttggatagcg ccattaggtg aaaatgtgga taaatttgaa gaaagtatta caaaatatac
     1321 tggttctaag ggcggagctt ctgcgttaag ttcaggtaca gctgccatac atcttgcctt
     1381 aagactgctt aatgttggaa aaaacgatat tgtctttgct ccttcattta cttttatagc
     1441 tacagtaaat cctattttat atcaaggggc tgtaccagtg ttcattgact cagaacctaa
     1501 tacatggaat atgagccctg ttgcactaga gagcgcatta gaagaagctg aaagaaacaa
     1561 ccaattacct aaggcaatca tcgtagtgaa tttatatggt caaatggctg attatgaacg
     1621 aattttagct attgcaaacc aatttaatgt tccagtgata gaagatgcag cggaatcgtt
     1681 aggttctact tataagggaa tttcgtcagg cttatttggg acaattggga tctattcatt
     1741 taacggtaat aagatcatca caacctcagg tggaggagct ctagtgtcta gtgataaaaa
     1801 atatgttgag cattcaagat ttttagcaac acaagcaaga gatcaagcac cgtattatca
     1861 acatagcgaa ataggttata attaccgtct aagcaatatt tctgccggta tcggacgtgg
     1921 acaaatggaa gtattgaatg atagagtagc taaacgaaga gaaattttca atcgatataa
     1981 ggaagctttt tctggaattg atagaattga aatgatgcca gaagtggatg gcatggtgcc
     2041 aaatcgttgg ttgtctactt taacgatcaa tgattataat tctattgatc aagtagttaa
     2101 cgtaataaat aaactaaatg aaaaaaacat tgaaacaaga gctttgtgga aaccactaca
     2161 tttgcaacca gtatttcaag gggtaaaaat gtattaccat gataataatc ttagtgtgtc
     2221 agaaaagtta tttaatagcg gcttatgctt accttctgga agtaatatga cagatagtga
     2281 acaagaattt gttattgatg agtttaaaaa aatattcaag taggtgtgat attttatgaa
     2341 cataggaatt attggtttag gttccatggg gaaaagaaga cttagactca ttcaagaaca
     2401 ctttaatgat attttactat gtggtgttga tactaatgag gcgagacgaa aggaagttga
     2461 aaaggaattt ggaataccaa cttataatag tctaacagag gcaaaaaatt tgtttgaaat
     2521 aaattcagtt tttgtttgta catcccctat aacccatgaa tttattataa aagaggcttt
     2581 aaatttagat tgtaatatct ttacggaaat caatttatta aatgaata
//
LOCUS       DAZUJR010000169         2550 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.174, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000169 DAZUJR010000000
VERSION     DAZUJR010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2550
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.174"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1004
                     /locus_tag="ACG804_002881"
     CDS             <1..1004
                     /locus_tag="ACG804_002881"
                     /EC_number="4.2.1.115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050377 - UDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 4,6-dehydratase family
                     protein"
                     /protein_id="HFS4833742.1"
                     /translation="KGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFYMQ
                     QELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNVMG
                     TQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIFSC
                     VRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSKFG
                     ETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEIER
                     SYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVTW"
     gene            1016..2020
                     /gene="neuB"
                     /locus_tag="ACG804_002882"
     CDS             1016..2020
                     /gene="neuB"
                     /locus_tag="ACG804_002882"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0016051 - carbohydrate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HFS4833743.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            2017..>2550
                     /locus_tag="ACG804_002883"
     CDS             2017..>2550
                     /locus_tag="ACG804_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase"
                     /protein_id="HFS4833744.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDT"
BASE COUNT          931 a          332 c          510 g          777 t
ORIGIN      
        1 ttaaaggaaa aacaatatta gtaactggcg gaactggttc cattggaagt gaaattgttc
       61 gtcagctttt aaaatatgaa ccaaaagcta tcagaattta tagtagaggt gaagaaaaac
      121 aattttatat gcaacaagag ctctcaaatc acactaattt gagattttta attggtgata
      181 tcagagactc tcaaaggatt gattatgcat gtcgtgatgt ggatattatt tttcatgctg
      241 ccgcaatgaa acacgttcca gcaagtgaat ataatcctat ggaagctgta aaaacaaatg
      301 tgatgggaac tcaaaatgta atagatgcag cgatcaaaaa taatgtaaaa cattttgtag
      361 gtatcagtac agataaagta gtgagtccta ctaacaccat gggtgcgaca aagttattga
      421 gtgaaaaatt aataatagct gccaatcagt ataaaggaaa aacagaaaca atattttctt
      481 gtgtaaggtt tggaaatgtc atggggtcaa gtggatctgt tattcctctt tttagtaaac
      541 aaataaaaaa caataaagat attactttga cagatgttga tatgacacga tttatgatgt
      601 caataccgga tgctgcaaga ttagttctgt ctgctgctat gaattcaaaa tttggagaaa
      661 catatgtctt aaaaatgccg gcaatcaata ttttaacttt agctcaatca ttaataaaaa
      721 tatataatga tacacatgat gaaaaatata gaggtgaaat aaaagttgta ggtatcaggc
      781 caggagaaaa attatatgaa gagctaatga ctacagacga aattgaacgc tcatatgaaa
      841 atgataaaat gtatatcatt ccaccacact atcatgctac tgacgaactg tacaaagatt
      901 atgaaaaaat taaaatcact gcatactctt cagatgcaac agaattaatg agtggacagg
      961 aatttattag aatcgcaaaa gagaataatg tcgtgacttg gtaaggagtt ttatgatgaa
     1021 atcagaagta tatgtaattg cagaaattgg tgtaaaccat aatggaagtc tagatttagc
     1081 tttagaaagt attgataaag ctaaagaatg tggagctaac gcggttaaat ttcaaacatt
     1141 taaaacgaat aagctagttt ccaaaaaggc tccaatggca aaatatcaga aggataatct
     1201 taaagaggac agttctcaat ttgaaatgct aaaaaaatta gaattatctc aatctgattt
     1261 tattagaata aaagattatt gtatacaaaa taaaattgat tttttgtcta ctccttttga
     1321 tgaagaaagt gcagactttc taaaacaaat tggtgtacaa ggatttaaaa ttggctcagg
     1381 agatttaaca aatttacctt ttcttagaaa aatagatatg tatgggttgc cagttttatt
     1441 atctacaggt atggctgata ttcatgaggt cagtgaggct gtagattgtt tcatagatag
     1501 tccagttact attttacatt gtacttcaaa ttatccggct agttctgaag atattaattt
     1561 attggcgatt aacacattaa aagaaatgtt cgggataccc gttgggtact ccgatcattc
     1621 attgggatat gatgttggta tttgtgctgt tgcgatgggt gctaaggtaa ttgagaaaca
     1681 ttttaccttg gataaggaac tacctggtcc agatcataaa gcttctttag atcctcagga
     1741 atttgcagat tttgtaaagc atattagaaa cactgaaata tttttaggtg atggtgttaa
     1801 gcgagcaatg ccttctgaac ttagtacaaa agaagtatca agaaaaagcc tagtggtcac
     1861 tgagaattta aatgtgggag atattcttac agagaaatct cttacaataa aacgtcctgg
     1921 aaatggaata gctcctaagt ttttatatca atatattggc aaaaaagtta aaagaccaat
     1981 aagtgcagat agtgttctgc ttgaggaaga tgttgaatga aaaaaatact tatagtaagt
     2041 ggaacacgag ctgattatgg aatatataaa cctgttgctg agaatttact acaagataat
     2101 tgggatgtat catttgttgt ttctggaatg catttatccc ataaatatgg atttactaaa
     2161 gaattgatct tagctgacgg atttagaatt agtggagaag ttcaaagttt gtttttagag
     2221 aacaataagg gaaacatggc tcggtctgtg gcattagaga taaatggttt cacaaatata
     2281 tttgaacaaa ctagccctga ttttgtatta ttactagggg atagaggaga aatgttggca
     2341 gctgcgatag cttgtttgta tcttggaatc aaaacagcac atattcacgg aggcgaagtg
     2401 tctggtactg tagatgaatc aataagacat gccataacga aaatagcatc tgttcatttt
     2461 gctgctacgg aaaaaagcaa agagcgttta ataaaaatgg gggaagattc ttggagagtt
     2521 tttcccgtcg gagctcctag aatagatact
//
LOCUS       DAZUJR010000170         2513 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.175, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000170 DAZUJR010000000
VERSION     DAZUJR010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2513
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.175"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..923)
                     /locus_tag="ACG804_002884"
     CDS             complement(<1..923)
                     /locus_tag="ACG804_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFS4833745.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIY
                     RADVNQAYNTSGNVGYHVSFNMRNFPNKKVYV"
     gene            complement(920..1144)
                     /locus_tag="ACG804_002885"
     CDS             complement(920..1144)
                     /locus_tag="ACG804_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HFS4833746.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            complement(1141..1434)
                     /locus_tag="ACG804_002886"
     CDS             complement(1141..1434)
                     /locus_tag="ACG804_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833747.1"
                     /translation="MINLGEWGMIAGSITAIVSLILLVIRPIAASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERRK"
     gene            complement(1471..1608)
                     /locus_tag="ACG804_002887"
     CDS             complement(1471..1608)
                     /locus_tag="ACG804_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HFS4833748.1"
                     /translation="MYSYEDIKLMYDWGCFTNEQVMVFVPLCITDEEADKIINKDKSA
                     S"
     gene            complement(1610..2041)
                     /locus_tag="ACG804_002888"
     CDS             complement(1610..2041)
                     /locus_tag="ACG804_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833749.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
     gene            complement(2055..>2513)
                     /locus_tag="ACG804_002889"
     CDS             complement(2055..>2513)
                     /locus_tag="ACG804_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833750.1"
                     /translation="AKYLKTHVEAIDGKEALVQTDGDQAIAGHKNFSGSVTINNKRVL
                     TTDDNRYEVVNLVVTNGNTGTAKLYREGKTVSIYFVALNGKSSGGNDSVILTVPEGYR
                     TPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSAYSFVITYSI"
BASE COUNT          696 a          527 c          397 g          893 t
ORIGIN      
        1 acatagactt tcttattagg gaagttacgc atgttaaaag atacatgata gccaacattt
       61 ccagaagtat tataagcttg atttacatct gctctataaa ttccatcagc tcttactcga
      121 gctaattctt tcccagtatt gtaatccata atgaagatat actcgtattt atagttagca
      181 atgtgccatc cagctacatg caaatttgca ttttcgattt ctccaaactg atcaatgtgg
      241 gcgtaattcg ttccatctgt cagtgtagga ttagctgcac cagctcgtgt tggatcaatg
      301 acaggcttgt tttcagaagt tgttggattt tcatcggtaa atccatgagc taaatcatat
      361 gctaattttt ctttacttac gcccatttca gaaagataac cgtaaggatc tgtatgatcg
      421 ccccagatgt tttgtgttac ccataaatgc gatttgattc ccggttggtt ataaggagtg
      481 tccaacgtta atggaatacc atatttcatt gctgaatctc tagccaattc aacgtatgcc
      541 ttgtagtttt tctcaaacgt tgctttatca tgtgtgtgtt gtaactcaat ctgcacagga
      601 ctgttggcat tagcatacga accagcaccg tactgtacat aaccaggttg accgacttga
      661 taaacaattc cgccgtctcc cacaatataa gcagtataag cgctagtcca tgaacgttgc
      721 atatactgcg cttcattgcg tcctgttgct gtttcattag ccgtttcatg cagtaaaata
      781 tactgattat ttgctacttg tgagctacct tcatttgcgc ccaaattaaa ttcattgttg
      841 atagtatagg caaatccgtt aattggcaat aaaaaaagag ccgttaacag gctcatcgca
      901 gtaatagtaa ttttcttttt catttgtttc ctccttcttc gctttcagcc gagaacattt
      961 tgtaggttcg atttgataca cccaacacac tccctaaaaa cgcgccaaaa ccagtaatga
     1021 tgacaacaca gatatctgtg tactgccaat tgagcgcttt accaactaac cccacgaaag
     1081 tagctagtgc gggaataatt accagtgcga accattttag tacttcgaac gttttattat
     1141 tcattttctt ctctccctaa acaaagtttt gatttgttgc gtgtgttcca ccaatttttc
     1201 tgtatgtgta tctaatcttt catcgtgttt ctttagttct tcatgaatca tcaatcgatc
     1261 tgatttgctc gattctaaat ctttagtcag caaatctaaa ttgtggctta cttttgaaag
     1321 agtctcagta attttcgaga aagatgcagc aatcggtcta attactaata aaatcaaaga
     1381 aacgatagcg gttattgatc ctgctatcat tccccattcc cctaaattaa tcatgtgaca
     1441 actcctttac cttaaataaa aacgcatcaa ttaagatgcg ctcttatctt tattaatgat
     1501 tttatctgct tcttcgtctg taatgcataa tggaacgaaa accattactt gttcgttagt
     1561 gaaacagccc cagtcataca ttagtttgat atcttcatat gaatacatgt tacttcccac
     1621 cttgtaattg ttttttgatt tcttcgattt ccttggtatt ttgtacagaa gcaagcatcg
     1681 tttttgaatt caactgcgct aaactttctg acttttcttt caataagaca ttttcttgct
     1741 tgattgctac attgtttagc attgctttag aatttagctg tttcaattca tcattttctg
     1801 ccttcagcgt ttcgtataat gccttaatat tagccaattc atctacgcta tcaacagcat
     1861 tccctttttt ctcttcttca gtagctaact caacccactg ttttttatca aaatcaaatc
     1921 ttggtctcca gttaggaact ggtggtttaa tctctgtaca gttttcaggg atattttctt
     1981 gattgttcaa aatgatttgc tcgaatccgt aaggcttgat tgatttgtaa actactttca
     2041 ttagatttcc tcccttaaat tgaataagtg ataacaaatg aataagctga tccataactt
     2101 gaatttcttc tccatttaat ggctccgtct gcgccaatag atagttgagc actgttcaaa
     2161 gtagaacggt ctattgaccc aaccagttgt tcaaaactaa ttggtgtccg atagccttct
     2221 ggaacagtta aaataaccga atcattcccg ccactacttt ttccgtttaa agccacaaaa
     2281 tatatagaaa ctgtttttcc ttcacgataa agctttgctg tccctgtatt accgttagtg
     2341 acaaccagat ttaccacttc atatctgtta tcatcagtcg tcaaaacacg tttattattg
     2401 attgttacag aacctgaaaa attcttatgt cctgcaatgg cttggtctcc atctgtctgc
     2461 accaatgctt ctttaccatc aatagcttct acatgcgttt ttaagtattt agc
//
LOCUS       DAZUJR010000171         2420 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.176, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000171 DAZUJR010000000
VERSION     DAZUJR010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2420
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.176"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            42..2195
                     /locus_tag="ACG804_002890"
     CDS             42..2195
                     /locus_tag="ACG804_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan D,D-transpeptidase FtsI family
                     protein"
                     /protein_id="HFS4833751.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
BASE COUNT          830 a          430 c          541 g          619 t
ORIGIN      
        1 gtacaatgaa gcatgaatgt aaataggcgg aaggatagga aatgatgaaa gattttatga
       61 aaaaaatatt aaatacttct tggttagaaa aaataagaaa aggtgcacaa gaacctaaga
      121 acaaaacgtt tcgccggtcc catgttcctt ttcgcttaaa ttttcttttt ttcattatat
      181 ttacgttatt tgttgcgttg attgctagat tgggttattt gcagatcgtg aacggcgaag
      241 agatggaggc gcgagtgaag tctacttcta cgattacggt ccaagaaagt actcctcgcg
      301 gaatgatcta cgactccaca ggaaaagctt tagttacgaa taaagcgaat caggccatca
      361 catatacgag aggaacacaa gttacggcta aagatttgct tgaaatcgca acgaagctga
      421 actcgctgat cgatgttccg gtagatgaaa atctgacaga tagagataaa aaagattttt
      481 ggctggctga tcccaaacat ttgaaagaag ccacaaaaag actttcggca aaagaaaagc
      541 aattagggaa cagcgaacaa tatagtgcga tggtcaataa agtcacagct gatgagatta
      601 atttaaacga ggagcaatta aaaattgcta ccatctttaa acggatgaat agtgcatatg
      661 aattaaacac tgtctatatc aaaaactctg gtgttactga tcaagagtta gctgttgtgg
      721 cagaacgcgc ttctgaactt ccaggagttt cgactggcac agactggaca cgagaatata
      781 atgcagcaag ttcactgaaa agtattcttg gcagtgtgac gactgaaaag caaggacttc
      841 cagcagatga agcagagaaa tacctagcaa aaggttattc tcggaatgac cgtgtaggac
      901 aaagttattt ggaaaaacaa tatgaagatg tcctgcaagg aaccaaaacc caatatgaag
      961 tttcccttga taatgaagga aatgtttcga atcaaaaaga aatcttctct ggggaaaaag
     1021 gttctaattt aatgttatct atgaatgcag aattccaatc aaaagtagaa gaaattttga
     1081 aaaggaatta tcaaacattg atcaacaacg gcaaagcaca gtattcgcct ggtgcttatg
     1141 cagtggctat gaatcctcag acaggagaag tgctagcaat gactggtttc agtcatgaac
     1201 aaggttccaa agaaatcacc gagaatgctt taggcacgat tactagcgcc tttgatccag
     1261 ggtctgtagt caaggctggt actttgacag caggctgggc aagtaacgcg atcagcggaa
     1321 atcaagtttt gattgatgag ccgattcgtc tgcaaggtgc ttcagaaaaa agctctgtct
     1381 ttaatcgaag cggacaagtt gctcttgatg cagtcaaagc atcggaattg tcttctaata
     1441 cgtatatgat caaagtggcg ttaaagatgt taggactaga ctatacacct ggaatgggac
     1501 tacctagttt agatgaagaa gctaaagctt atcagcaatt gagagactct ttcaaagagt
     1561 ttggtcttgg tacaacgact gggatcgatt tgccgaatga atctcctggg atctcacgtt
     1621 ctgttgatta tatgaagaag ttcaatgcgg ataatggcaa agaatggtat gctccaggta
     1681 actttaccga tttggcattt ggacagtttg acacatatac accaatccaa ttagctcaat
     1741 atgcttcaac agtcgctaat ggcgggaaac gagtacagcc gcacctagtc aaagcgatct
     1801 atggcaatga cgaaaatgga aacttgggtg aagtgaagaa agaaattggc acaacagtag
     1861 aaaatacggt caatatttct gcagaaaata tggcgatcct ccgtgaagga ttccaccaag
     1921 ttgtccatgg taccgatcct tacacaacag ccaaaccatt agccagtgcg aaaatggacc
     1981 tttccgcaaa aacagggact gcagaaacgg ttgcggaagg tcatccagat attgcgacag
     2041 tcaatagtaa tatcgtggca tacggaccaa cagacaatcc ggaaattgcc atcagtgttg
     2101 tcttgccgaa cttattagac gaacaagacc acataaactt gacgattgct aaagaaataa
     2161 tggacgcgta ttatgatatg ttcatggcaa aataaaaaag aggtcgtgaa aaagccgctt
     2221 agtttcgagt atgaagaaaa attttgtgaa aatagcttct cacatttttg cttaaatttg
     2281 acttcatacc gagaaactgg cttttgaaca ccgtttactc ggcaaaaaag gttgtgacaa
     2341 aaattgtggc tctttgtcaa taaggactga tgagttgtgc aaaatcaaat ctgagtcaga
     2401 atgaaccaca ttctggctca
//
LOCUS       DAZUJR010000172         2398 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.177, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000172 DAZUJR010000000
VERSION     DAZUJR010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.177"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            207..2069
                     /locus_tag="ACG804_002891"
     CDS             207..2069
                     /locus_tag="ACG804_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFS4833752.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2398
                     /locus_tag="ACG804_002892"
     CDS             2069..>2398
                     /locus_tag="ACG804_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFS4833753.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          865 a          353 c          466 g          714 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataat
//
LOCUS       DAZUJR010000173         2338 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.178, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000173 DAZUJR010000000
VERSION     DAZUJR010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2338
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.178"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..535
                     /locus_tag="ACG804_002893"
     CDS             <1..535
                     /locus_tag="ACG804_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="beta-1,6-N-acetylglucosaminyltransferase"
                     /protein_id="HFS4833754.1"
                     /translation="DYPRINRNNTTAFKIFRAIINRCLRMIKLPPKIRHHKFDLYHGS
                     QWWALSKECLTELIQMYEQNQQDYLNFKIGMFAPDEKFFHTLFFNSSFKNKNVIGGPD
                     LPLELKNIEETTLQTSKLANIHIIDPSMNKWFDERDIDQIKESEKLFVRKVKSDYSDK
                     LLNRIDKEILKVGNIDE"
     gene            528..1955
                     /locus_tag="ACG804_002894"
     CDS             528..1955
                     /locus_tag="ACG804_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HFS4833755.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIINRENFLIPSIYNFGYLL
                     ITLIVIFPADFSQSEEEKKKKMVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPG
                     LLARQGFIEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQI
                     FYITLSSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFS
                     FGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIW
                     KAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLV
                     SSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFN
                     KRDVISIVFWYYLGSISYLYLKKEN"
     gene            1957..>2338
                     /locus_tag="ACG804_002895"
     CDS             1957..>2338
                     /locus_tag="ACG804_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833756.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTY"
BASE COUNT          805 a          277 c          376 g          880 t
ORIGIN      
        1 tgattatcct agaattaata ggaataacac aactgcattt aaaattttta gagctataat
       61 taatcgttgt ctgaggatga ttaaacttcc cccaaaaatt agacaccata aatttgattt
      121 gtatcatggt tctcaatggt gggctttgtc gaaagaatgc ctaacagaat taatacaaat
      181 gtatgaacaa aatcaacaag actacctgaa ttttaaaata ggtatgtttg ccccagatga
      241 aaaatttttt catacacttt tttttaattc ctcgttcaaa aataaaaatg ttattggagg
      301 accagattta ccacttgaat tgaaaaatat tgaagaaact actttacaaa cttcgaaatt
      361 agcaaatatt catattattg atccttccat gaacaaatgg tttgatgaaa gggatataga
      421 tcaaataaaa gaaagtgaaa aattatttgt aagaaaagtt aaatcggatt actctgataa
      481 actattaaat agaattgata aagaaatttt gaaagttgga aatatagatg aatagaatag
      541 tacctgtttt agagaagagt ttattaagtc gagatgcgtt tcgagtaata aatttaatca
      601 tttgtctgct ttattttatg cctagtactt ttaatgtaac taatatcccg atgaaaatag
      661 cttttgcttg gggtggaatt atagttttgt atgaggtttt tataaagaaa aattttttta
      721 aaatgcgttt ttcttggcta ctgattggag caatgattag ttttatctta actataatca
      781 ttaacagaga aaatttttta attccatcta tttataattt tggatatttg ctgattactt
      841 tgatagtaat ttttcctgca gacttttcac aaagtgaaga ggaaaaaaag aaaaaaatgg
      901 tgtattttaa taatgttttc attatcataa tttttttagc tgcgctaata tctatctatc
      961 aatttatttt tttgatttct tatcatgtcc caacaggaac gccaggatta cttgcaagac
     1021 aaggttttat tgaacatcgg ttatttggtg tctatacaag tccaaatgtt ggagctatgt
     1081 ttggatatac ttctattatt ttaagtttaa ttagtgtatt aatttcaaaa ataacaaaaa
     1141 cgattcgtgt tttttatatg atgaatttta tcgtacaaat attttatatt acactttctt
     1201 cgtctagagg tgcccaggta gtaatttgtt cttttttagt attatttctt ttgttgtttg
     1261 ccaattcaaa atttagaaag agcattagag aagtactacc tgtaaaaatc aaatggatgg
     1321 taagcatatt attagttcta ttggtatatt tttcttttgg tactaattat gctaaggatt
     1381 ttttagcaac aattcctgta tcgattgata gaaaagtaga agttatagag tcaaatgaat
     1441 cagataaaac tccacttcca gaaaaagaag taatattaca gcattctagt gataactccg
     1501 aaatttcagc tggtcgtttt acgatttgga aagctgcgct taaagttata agaccaactt
     1561 tgttatttgg ttatggagag accgatttct atgggaatag cgatgcaaaa tttttgaaaa
     1621 aagtagatct tgatactaca gatgtgaatg aactaaaaag agcacatgga aacatgcata
     1681 atggatttct tcaagtactt gtatcaagtg gtataattgc ttttatatgt atctatgctt
     1741 tctatgtgtt aaatatcttt agtttactca aaacattttt tagaagtaaa gtgaattatg
     1801 cgtttcttgg tattgtttta atttttatac tatctatttt tatagatgaa atggtggagg
     1861 ctcatgtact tttcaataag cgcgatgtca tttcaattgt tttctggtat tatttgggaa
     1921 gcatttctta cttgtattta aaaaaggaga attaatatga agacagcttt cattgcttgg
     1981 actcctttac atttgattaa tatattaaat gtttatcaaa atttttaccg agaatcaaaa
     2041 ggagatttat ttatttattc tgaatttgaa aacgctagaa gatatagtga gcgtataaaa
     2101 gaattagggc tatttaatga tgttgttttt gtgaatcacc ggaaaatcgg ttcttccttt
     2161 aaacgtaaaa ttaacttgtt aactaaccat aatcaatttt tctcggatga tttatccgtt
     2221 tatgatgaaa tttttataca gggggaaaat tatttcacaa aaatactttt ctccaatgtt
     2281 tacaaaaaaa atccagatgt aaaactaaat tatatagaag atggtttggg tacttatt
//
LOCUS       DAZUJR010000174         2326 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.179, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000174 DAZUJR010000000
VERSION     DAZUJR010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2326
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.179"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(104..856)
                     /locus_tag="ACG804_002896"
     CDS             complement(104..856)
                     /locus_tag="ACG804_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFS4833757.1"
                     /translation="MSYPIILCEDQIIQLNQLERIIDNFILFHDKVFKIVLKTQSPLE
                     VKKYLKQFRPKQGIYFLDIDLNHEVNGIELAEVIRKYDVQAKIIFTTTHDEMLPVTIK
                     RRVETLGFVTKDQTLDEYRNEIVELLLLAQERIDATKQVTNQAFVFSIGSQTFTFDIN
                     DIYFVEASKLPHRLSLCTKDGQYEFYGRISELEKKYPMLTRISRACLVNIFNVKEIDF
                     KKRSLYFDSELARNFTLGKAQKIKEKLKESTV"
     gene            complement(871..2118)
                     /locus_tag="ACG804_002897"
     CDS             complement(871..2118)
                     /locus_tag="ACG804_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFS4833758.1"
                     /translation="MFVGNFFFFLLFYMTNTDLNKRKYLFVCLLIPLTFFVELFTDVS
                     AAIPIIGSYFILKEKKKTNIVLLNKLLLCMLIDDFRSIITSMVMTYMFSFEGIKGYGY
                     VVFQIMLDSLFLLMFIWLYRKLAINRIVEQSSSKLTAIFMIYLLTIGLFVSYVAHQYQ
                     VFDHFVFGVLIFLIIQMFVVLFLFIRITIRQREQYEQQLKRKELVYLKKYTDSLEKDQ
                     EKFARFRHDYKNLLLSLKEIANQNHDSILEKEIKELEIYSNSYLTNKFEYRYLKNIKN
                     EYLKSLLIAKLYQANNNKICCKFECPSTIIEVPVPIFDCIRVLGIILDNAIEASIESQ
                     DRELSLAIYRDDKQIEISISNSCREILLSIDTLMKKGITTKKGHQGLGLSSIEEINKK
                     NPNMFVNYQNDPYQFTTQVILLF"
     gene            complement(2194..>2326)
                     /locus_tag="ACG804_002898"
     CDS             complement(2194..>2326)
                     /locus_tag="ACG804_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HFS4833759.1"
                     /translation="RLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFSLFKKCN"
BASE COUNT          811 a          378 c          275 g          862 t
ORIGIN      
        1 cagctataaa aattggtaca actttaatag gattcagaaa aatttgcact agtgaaggaa
       61 tctattttat tagaaaaatg caatctccct aaagaaaaaa ccactaaaca gtgctttctt
      121 tcaacttctc cttaattttt tgtgctttcc ctaaagtaaa gtttctggcc aactctgaat
      181 caaaatatag tgaacgtttt ttaaaatcta tttctttaac gttaaagata tttactaaac
      241 acgctcgact aattcttgtt aacataggat atttcttttc aagctcacta attcttccat
      301 aaaattcgta ctgcccatct ttagtacaca atgataatct atgtggtaat tttgaagctt
      361 ctacaaaata aatgtcattt atatcaaaag taaatgtttg agaacctatg gaaaaaacaa
      421 atgcttgatt cgtaacctgt tttgttgcat ctatcctttc ttgcgctaat aacaataact
      481 caacaatctc gtttcgatac tcatctagtg tttgatcttt tgttacaaat cctaacgttt
      541 caactcttct ttttattgtt acgggtaaca tctcatcatg agtagttgta aaaatgattt
      601 ttgcttgaac atcatatttt ctgattactt ctgctaattc tataccgtta acttcatgat
      661 ttaaatcaat atctaagaaa tatattcctt gctttggtcg gaattgtttg aggtattttt
      721 taacttctaa cggactttgt gttttcaata ctatcttaaa tactttatcg tgaaaaagaa
      781 tgaaattatc aataattcgt tctaactgat ttaattgtat aatttgatct tcacataata
      841 ttattggata actcataaat cctccttccc tcaaaacaac aaaataactt gagtagtaaa
      901 ttgatacgga tcgttttgat agttcacaaa catattggga ttctttttat tgatttcctc
      961 tatactagat aaacctaacc cttgatgtcc cttttttgtt gttattcctt ttttcattag
     1021 agtatctata gagagtagta tctctctaca actattcgat atcgaaattt ctatctgttt
     1081 atcatctcgg taaatagcta gagacagttc tctatcttga ctctctatag atgcttcaat
     1141 tgcattatcg agaataattc caagcaccct aatacagtca aatattggaa caggaacttc
     1201 aataatagta cttggacatt cgaatttaca acaaatctta ttgttatttg cttggtatag
     1261 cttcgctatc aacaaacttt tcaaatattc attttttata ttttttaaat aacgatattc
     1321 aaacttattg gttagataag aattagaata gatctctaat tcttttattt ctttttccaa
     1381 tatcgaatca tggttttgat tagcgatttc ttttaaactc agcaataaat ttttatagtc
     1441 atgtctaaat ctggcaaatt tttcttgatc tttttccagt gaatcagtat atttttttag
     1501 ataaaccaat tcttttcttt tcaattgctg ttcatattgt tctcgttgcc taatagttat
     1561 tctaataaat aaaaatagaa caacaaacat ttgaatgatt aaaaatatta agacaccaaa
     1621 cacaaaatga tcaaatactt gatattgatg agcaacataa gaaacaaata aaccaattgt
     1681 aagtaaataa atcatgaata tagcagtaag tttagaactg gactgttcaa caatcctatt
     1741 tatagctaat tttctatata accaaataaa catcagcaaa aacaaagaat caagcattat
     1801 ctggaatact acataaccat acccttttat cccttcaaat gaaaacatat acgtcataac
     1861 catggaagta ataatagatc tgaaatcatc aataagcata cataatagta atttatttaa
     1921 aagcactata ttagttttct tcttttcctt taatataaaa taacttccga ttataggtat
     1981 agctgcggaa acatcagtaa ataattcaac aaaaaaagtg agtggtatca ataaacatac
     2041 aaaaagatat tttcttttgt taagatcagt attagtcata taaaataaga gaaaaaagaa
     2101 aaagtttccc acgaacattc ttaatagata agcttttgta tcgatagtaa tcaagagatc
     2161 ccctcctgat tttaggatat cataaaaaaa attttagtta cactttttaa ataatgaaaa
     2221 aacacattcc actaaatttg atgccggttt tccttgaggt tttgttccag cacctccttt
     2281 aattttttta agctcttgat ctgaacattg tttagcattt agtcta
//
LOCUS       DAZUJR010000175         2313 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.180, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000175 DAZUJR010000000
VERSION     DAZUJR010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2313
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.180"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            191..445
                     /locus_tag="ACG804_002899"
     CDS             191..445
                     /locus_tag="ACG804_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFS4833760.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            446..763
                     /locus_tag="ACG804_002900"
     CDS             446..763
                     /locus_tag="ACG804_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFS4833761.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1322..2257
                     /locus_tag="ACG804_002901"
     CDS             1322..2257
                     /locus_tag="ACG804_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833762.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILINRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGTRGAS"
BASE COUNT          846 a          313 c          434 g          720 t
ORIGIN      
        1 gatgttaacg gaagtgtatg gtgagtagtt cactcgtatt ttgatatcgt ttgtatatgt
       61 tttcagcgtt ctaagtggct tattttgtcc aataataata tggagtggaa tcccttaaga
      121 aacaccgttg gcaattgttg ttataacatg ttataattta ttcatcaaaa actaaaagga
      181 gtgtgataac atgggaaaag aactaaaggt tagaaagatc ggcaatagcg tgggagtgat
      241 ccttccaagc tctcttggat taaaaagcgg agacattatc caagccaaac aagaaggcaa
      301 cttattcata ttagatacta ctcaaatagc aaaagaacac gatcgcaaat tgattgaaga
      361 aagtttccaa gactttgaga aaggtttaac agtttcagaa attgaaatgg taaaagcttt
      421 cggaaaatac ggctggagtg aatagatgaa agagtacacg ctagtttatt ctaaaagttt
      481 tcagaccagc cttgaaacga taatagaaga atgggaaaat gagcttgctc tttctccagc
      541 cagcataaaa agatttgtag gtgcgatcca gaaggcttta gaactaacca aaaattttcc
      601 aactatgcat gaggaagttt ccgaaatcta tggaatggat atcccaacat atcggatcgt
      661 gatcggcaaa agctatgcct tattttatcg gatcgaccat gaaaaaaaag agatacttgt
      721 aggacgtatt ttccaatcta aacaaatgaa actaggcttt taacaataat taggaaaaag
      781 tcgctcatcc tctacaggtg ggtgattaat gccgctcgat atggttgtta accgtcggtt
      841 actcgaagat tgatatataa gacttagtac ctttttattt tgctccatgt tatggccgaa
      901 ggtctaaaga tacaatcatt agtctagaga aaaattaaga accgtaggaa ctacggggat
      961 cgcttggtga ataagagaca ctgctattag tgaaaaaata agatatcaag tacgctctat
     1021 tcccaaaaat ttcgtgactt tactcatgag aggttcaagt agtatatttt taatcaaaat
     1081 tgacgtaact tttaataaat actacctaaa taaggtagta tttatttttg tgttttaaaa
     1141 gaggaagtcc aatatatcta tgggaaactt cttaaatatt atgttggtac atgaaaatat
     1201 acatccctgc tagactattt acaacatttt actttgtacg tattcttgtt ttaaaaggaa
     1261 tgggataaaa tataggtaca ataactattt gatgctaaat ataattaatg gaggagagat
     1321 agtgaacata cttaatgaaa aaagatatgt atggtttgct ggtaaaaaat atattactac
     1381 tttcaaaaga ttatccgagt taatgcagca gactgttaaa agtgctatgc ctgaaggata
     1441 caagtttaat tttgttcaat cttcagtatc tactgaaagt atctattttt caattctttc
     1501 tgagagtagg ctttttcatt ttagaataag ttctcatgta aagaaaactg atgttgatat
     1561 atatacgttc cgtacaaata attataaaaa tttaaatgat ttgagtagaa gtatcagtga
     1621 atatctcaag gggaatagct atctcaagat tcgattttca catatattaa ttttactacc
     1681 atatttgaat gagaatttca ccctaattca agtagataag tctttcattg cctcaggtaa
     1741 tcaaggaaat atgaatatta caagtaacaa aacgtcacgt gtgctattgg cgttgatggg
     1801 ttacggaatt ctttatagag atgaccaaaa tggccagatt ctaataaatc gggctgggcg
     1861 ttcattatta atgaaatata gaaaatttat accggaagat tttcaaaact tacagttaga
     1921 aaacatgcgt ttagaagatt tatttagatt agcagaagat gataagtata gatttgaagt
     1981 tttgaaaatt caaaagaatg aactattgaa taagttatat cctgagaatg cgataaaagc
     2041 acattttggt gatgctaatc atatgtatag ttggttcatt cctaaaagat ttagagggaa
     2101 aatcaatgct ggagatcaag tgaaagtact caatcgaaat agtacagatg tcgtaatgat
     2161 aacagatatc tatgtagaag atgaagatat aatcaaatat atgaagcctg tgataaaact
     2221 tgttaataaa aataaaggaa cccgtggtgc tagttaattt tttcctagag aaaaatgtct
     2281 aaacatgttg gtaaatcaac aaaaaaacgc ata
//
LOCUS       DAZUJR010000176         2256 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.181, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000176 DAZUJR010000000
VERSION     DAZUJR010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2256
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.181"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            1..717
                     /locus_tag="ACG804_002902"
     CDS             1..717
                     /locus_tag="ACG804_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HFS4833763.1"
                     /translation="MKKRILVTIGLAFLLAGCTNGNESKKESTKETAKATVATTTTTS
                     TESKSTAASTETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNAD
                     KSAQLEAFMTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEW
                     SESGTGQADYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFN
                     ETANNELKNGFNQIVYGQAN"
     gene            916..2211
                     /locus_tag="ACG804_002903"
     CDS             916..2211
                     /locus_tag="ACG804_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFS4833764.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFKLRIMIRHGKTFLTK"
BASE COUNT          741 a          438 c          433 g          644 t
ORIGIN      
        1 ttgaaaaaaa ggattttagt aacaattggt ctagcttttt tgttagctgg ttgtaccaac
       61 gggaatgaat cgaaaaaaga atcaacaaaa gaaacagcga aagcaacagt tgcaactact
      121 acaacaacta gcacagagag caagtcaact gcagcaagta cagaaacagc agatacctct
      181 acttcgtcag agtcttccaa aacgactgaa acaactcaaa catctacttc aagttcttct
      241 gtagaggctt catcttcctc ttcagaaagc agcgaacaag ttgaacaaac actgtggaat
      301 gcagacaaat ccgcacaatt agaggcattt atgaccaaat ggggccaaac aatgggacaa
      361 caatacaaaa gttatacgaa tcaaatgagt gtggacttat atggtcttaa agtccctcaa
      421 gctattttga acggggagtg gaagatggct attggtggag tgcctgtttc tgcagaatgg
      481 tcagaaagtg ggacaggtca agcagactat caaatcacag ccgtctattc cgatgcagag
      541 acagaaccat atctgaaaaa gcacgtctat ctattcgggt ttcagcaaaa tcagccaaaa
      601 gtattggtga cacaacaaaa tcaggggaat cccgataatt atctttactt caacgagaca
      661 gcgaataatg aattgaaaaa tggctttaat caaatcgttt atggacaagc aaattaatga
      721 gataaacaag gggttgtgac atgtctttta tcacaacccc ttgctcagtt tatttgttag
      781 tcttttattt tttggctcta tactttttga tgttggtgaa cttcaccaac atcttttttg
      841 tataaaaaaa tatagaaaag acaccctgaa atcctttaga attaatttgg ctaccaattc
      901 ataggaggat tcaagatgtc tcatactcag cttatcaaag ataccctaaa tattctagac
      961 ctaaatatct atttcgagga aaattgttta actaaagaaa aatacaaagg gcaaatttgc
     1021 ttgatttaca aaggaactct tctgtacaag ccagaagagt gttcccattg tctttgtgtc
     1081 gtcccctcta ggatcattcg ttgggggacg acaaccgttc ggttgttact gaatgatgtg
     1141 tctgagtatc gcacttatct ggagctgaag aaacaacgat ttaaatgtaa gtcttgccaa
     1201 agaacattcg tagcggatac ctctgttgct gaaaaacact gtttcattag tcaaaaagtt
     1261 cgttggtctg tcattgctcg cttaaaagag aatacttcca tgacggaaat cgctcgtcag
     1321 aaaaatattt ccacttcttc ggtctatcgt gtcatgaagc gattctaccg cccattgaat
     1381 cctttcaaac agactttgcc aaaggtctta tgctttgatg aattcaaatc ggttcgaagt
     1441 gttgccagtg caatgagttt tatcatgatg gacggacaaa gccatgcatt attggatatt
     1501 gtcgaaaatc gacgcttgcc ttatttagaa cgctattttt ctcggttttc attagcgact
     1561 cgtgaagccg ttcaattgat tgttattgat atgtatgcgc cttatgtttc gttggtgaaa
     1621 aagcttttcc cgaatgctca gttgatcatc gatcgtttcc acatcgtcca acatattggc
     1681 agaactttct tgaatcatcg agtgaaagaa accacggtac gacttaaagg aaattcccac
     1741 tctcaacgag ggttagggaa aaaattgaag cgctattgga aactcctaca aaaagaagaa
     1801 gcaaagttaa actatgaaaa acgggtttgg cgtgccagtt ttaaagatta tttgactgaa
     1861 agtgagattg ccgatcgact gttagctgct tgtcccaact tacgccaagg ctatcagtta
     1921 taccaagaca ttctttatgc ggtaaagaaa agagatcagt cactatttga ggattgttta
     1981 actagagaca ttagcggtct gccagaaacc tatacaacca ctttacgaac gtttaaaaag
     2041 tttctgccac agatccaaaa tgcgcttcac tacagctatt caaacggacc attggaatgc
     2101 ttaaacaacc acatcaaagt attaaaacgc aatgcgtacg gctttcgcaa cttttacaat
     2161 ttcaaactac gaattatgat tcgtcatggc aaaacatttt taaccaaata aacagaacag
     2221 aaagaggttt tcttctttct gttctgtcca aattat
//
LOCUS       DAZUJR010000177         2242 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.182, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000177 DAZUJR010000000
VERSION     DAZUJR010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2242
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.182"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..365
                     /locus_tag="ACG804_002904"
     CDS             <1..365
                     /locus_tag="ACG804_002904"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833765.1"
                     /translation="EIVELKKRCNSLINTSKTVKTISHQTKESIKKILLIGVPGKIVI
                     REDYNFIITNPDTPLEDIIKIIEENDINELWITTFQLIPRMKKKIIQSLKNKIKIQEL
                     NDFTMLMKEENINGFKTR"
     gene            346..>2242
                     /locus_tag="ACG804_002905"
     CDS             346..>2242
                     /locus_tag="ACG804_002905"
                     /inference="COORDINATES: protein motif:HMM:NF019348.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HFS4833766.1"
                     /translation="MVLKQGKQDYQIIGYLEDDLNKIKINSDDVMYFFMTPLSDFPSS
                     VIDNVEGIQIYSNTLTKFGFIDDINESHSTRAQSLKEFLDPYIIVCTPKIKRNHEQAR
                     NYYQGDDLELIPKPKSEVFKNLIKENESLVPIPVFSINNSDSVIKDETSFENQLLNGK
                     LLGKIINFSKDNEDYPLNVFWENTDGSRVLFGEIIGQNNSMYGVAYRIEKDNFYKKFI
                     DEGSKNYVGYDDFINQTKDIIFVPYLLLQKIIETKKDINEGIENISDSKISPVSSIIT
                     EQTQIDISELEDKHAIQQNDHFSEHNEFIERFNQLTIRSKLHYSKRDLWNFHTAMLGD
                     SLVVLAGLSGTGKSQLVTSYAKALQLSDTQIKFISVRPFWEDDSDLLGYADTVNSVYR
                     PGDSGLIDALLEASRHKENIYMVCFDEMNLARVEHYFSQFLSVLEMEPNTRKIKLYNE
                     DLENKLYNSSTYPSTIEVGQNILFVGTINTDESTHQFSDKVLDRSNIISLELVPFHEI
                     SEVNDYIQSDQKKRNQLKYDDFKNFKNSNPTNGLTQKEKEMFWKLHLAINSKDKNIGI
                     GWRILKQIDEYLKNLPVQNDLSRKEAIDIQLVQRVLSKIRGSDEQLSELVGKWNENDL
                     KQVGEFEQ"
BASE COUNT          914 a          291 c          343 g          694 t
ORIGIN      
        1 atgaaatcgt tgaactgaaa aaaagatgta atagtcttat aaatacaagc aaaacagtaa
       61 aaactatttc acaccaaaca aaagaaagta taaaaaagat tttattaatt ggtgttccag
      121 gaaaaattgt tattagagaa gactataatt ttataatcac taatcctgat acacctctcg
      181 aagatatcat taaaataatt gaagaaaatg atattaatga attatggatt acaacctttc
      241 aattaattcc cagaatgaaa aaaaagatta tacaaagttt aaaaaataaa ataaaaattc
      301 aagaattaaa tgattttact atgcttatga aggaggaaaa tataaatggt tttaaaacaa
      361 ggtaaacaag attaccaaat tattggttat ttggaggatg atttaaataa aattaaaata
      421 aactcggatg atgtaatgta cttttttatg actcctcttt cagatttccc cagtagtgtg
      481 attgataatg tagagggtat acaaatatat agtaatacgc ttactaaatt tgggtttatt
      541 gatgatataa acgaatctca tagtactcgt gcccaatcac ttaaagaatt tttagatcct
      601 tatattatcg tttgtacacc aaaaattaaa agaaatcatg aacaagcaag aaattactat
      661 caaggtgatg atttagaatt aatccccaaa ccaaagtctg aagtttttaa aaatttaata
      721 aaagagaatg aatcattagt acctataccg gtcttttcta taaataacag cgattctgta
      781 atcaaagacg agacaagttt tgaaaaccaa ttactaaacg gcaaactact cggaaaaatt
      841 ataaatttct caaaagacaa tgaagattac cctttaaatg ttttttggga gaacactgat
      901 ggatcaagag ttttatttgg tgaaataatc ggacaaaaca attcaatgta cggtgtagca
      961 tataggatag aaaaagataa tttttacaaa aagtttattg atgaaggtag taaaaactat
     1021 gtaggttacg atgattttat aaatcaaaca aaagatataa tttttgtgcc ctatctatta
     1081 cttcaaaaaa ttatagaaac taaaaaagat attaacgaag gcatagaaaa tatctctgat
     1141 tccaaaatat ctccagtaag ttcaattatt actgaacaaa cgcaaataga tatatctgag
     1201 ttagaagata aacacgctat tcaacaaaat gatcacttct ctgaacataa tgaatttata
     1261 gaaagattta atcagctcac aattcgtagt aaattacatt actcaaaacg agacttatgg
     1321 aattttcata ctgctatgtt gggtgatagt ttggtggtat tagctggact aagtggtacc
     1381 ggtaaatcac aattagtaac atcctatgca aaagcacttc aattatcaga tacacaaata
     1441 aagtttattt ctgtgagacc cttttgggag gatgattctg atttattggg ctatgctgat
     1501 actgtaaatt ctgtctatcg tccaggagat agcggtctaa ttgatgcact attagaagca
     1561 tcaagacata aagaaaatat ttatatggtt tgttttgatg agatgaattt agctcgggtt
     1621 gaacattatt tctcccaatt tctttcagtt ttagaaatgg agccaaatac taggaaaatc
     1681 aaactgtata acgaagatct agaaaataaa ttatataact cttcaaccta tccttctaca
     1741 attgaagtag gacaaaacat attatttgta ggaacaataa atacagatga atctactcat
     1801 caattctcag ataaagtttt ggatagatca aacattattt cacttgagtt agtaccattc
     1861 catgaaatta gtgaagtaaa tgactatatt caatcagatc aaaagaaacg taatcaactt
     1921 aaatatgatg atttcaaaaa ttttaaaaac tctaacccta ctaatggttt gacccagaaa
     1981 gaaaaagaaa tgttttggaa actccattta gcaattaatt ctaaagacaa aaatatcggt
     2041 atcggttgga gaatattaaa acaaattgat gaatatttaa aaaatcttcc agtgcaaaat
     2101 gacttatcaa gaaaagaagc tattgatatt cagcttgtac agagagtatt aagtaaaatc
     2161 agaggttctg atgaacaatt atcagaatta gttggtaaat ggaatgagaa tgatttaaaa
     2221 caagtgggtg aatttgaaca aa
//
LOCUS       DAZUJR010000178         2236 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.183, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000178 DAZUJR010000000
VERSION     DAZUJR010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2236
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.183"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..607
                     /locus_tag="ACG804_002906"
     CDS             <1..607
                     /locus_tag="ACG804_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phage tail tip lysozyme"
                     /protein_id="HFS4833767.1"
                     /translation="DGFKACTDPRQAAYAFERNYERPAATHPERQDYAVNWYNKFKDL
                     KPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYSGYLGGCGMGAGTKYGLTHVIGNT
                     SAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIINWARGGQVGSWFADGTYGHTGVIR
                     GLANGRMQTYEQNTELGMICGKLDRQYYSASAISSIVIPPK"
     gene            620..1528
                     /locus_tag="ACG804_002907"
     CDS             620..1528
                     /locus_tag="ACG804_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HFS4833768.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKINYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FERWRQEQEHSFQDWREGQESDYLAWFESIKDILKTIDPGGVMLAELTDARVDIQGVR
                     HASISERLLADMDYLYQKLRATLFTIEYGEIEVTDILQDDLFSDNHEVEKVGTVAFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            1528..2148
                     /locus_tag="ACG804_002908"
     CDS             1528..2148
                     /locus_tag="ACG804_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833769.1"
                     /translation="MAKTKRMMETDEKTGVQRQFFPITHASAVLGLEEIIAGEATVLS
                     VNGKIGAVVITKEDLGLENVLTELPYASEEDDGIITAEMYQKILNSGEGDYVLPVATI
                     DRLGGIKVGELLTIDETGKVSAVRQSDVNFSLELKEKLDSLKNYTAGENITIDEDGTI
                     SSTGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
BASE COUNT          771 a          328 c          521 g          616 t
ORIGIN      
        1 tgatggattt aaggcctgta ctgatccaag acaagcagca tatgcttttg aacgaaacta
       61 tgaacgtccg gcagcgacac atcctgaacg tcaagattat gcagttaact ggtataacaa
      121 atttaaagat ttaaaaccag gaggagctac tggagaagca ggactaaaac atttagagtc
      181 tttgattgga caacgaattg gcaatggtca gtgttatggc ttgtctgcag aatattcagg
      241 atatctgggt ggttgtggca tgggtgctgg aacaaaatat ggtttaactc atgtgatagg
      301 aaatacttct gcagcatctg atattggtat tgcctatgat tggtctgctg ttggttggaa
      361 agtgattcaa aaccctagat atgatcaatt agtagttggt gcaattatta attgggcaag
      421 aggtggacaa gtgggttcat ggtttgcaga tggaacttat ggacatactg gcgttatccg
      481 aggcttagct aatggtcgta tgcaaactta tgaacaaaac acagagttag gtatgatttg
      541 tggaaagtta gatcgccagt attatagtgc aagtgcaatt tcttccattg tcataccacc
      601 aaaataggga ggtgatttaa tggcaaagtg gaatgtcata ttaagtacaa cagaacccta
      661 taattacgtg gggatgattc aagttcgaca aggcaataag aatacagagg ttatggaagc
      721 gactatagtt gaaaatggtc ttccctacga tttatcagaa tgtaaggtat attttgaatc
      781 agttgtaggt gggaaatatc cagtccaatt agaaacaaaa attgtggatg ctaaaaaagg
      841 gaaaattaac tatatttttg ataaatattc catgcagtgt ttacatcgac aaacagccaa
      901 tttcattata tttaaaggag aagacttgat tggaacaact caagacttct cttattttgt
      961 cattaatgct gtttcaaaaa cagaaggaga aatgggttct tattggcaat caatcgaaga
     1021 tttaattgcg gatatgacgg actttattaa tgaaaataaa ggcgatttta cggactggat
     1081 gaatgaaagg aaagaagaat ttgaacgttg gagacaagaa caggaacaca gtttccaaga
     1141 ttggagagaa ggacaagaat cagactattt ggcatggttt gaatcaatca aggatatttt
     1201 aaagacgatt gatccaggtg gagtcatgtt agccgaacta acggatgcgc gagtagatat
     1261 tcaaggagtt cgtcatgcgt ctatttcaga gcgtttgctg gcagatatgg actatttata
     1321 tcagaaattg cgagcaacgc ttttcacgat tgaatacggg gagattgaag tgactgatat
     1381 tttgcaggat gatctctttt cagataatca tgaagtcgaa aaagttggaa ctgtagcatt
     1441 cccgattgaa gaaggagcct tgatcatcgc aaccgttgat gatccaaagc aaaatgtgtt
     1501 cactcttgag aaagttgggg tgatctaatg gctaaaacta aacgaatgat ggaaacggat
     1561 gaaaaaacgg gtgtacaacg ccaattcttt ccaatcacac atgcttccgc agttcttggg
     1621 ttagaagaaa taatagcagg agaagcaaca gttttatctg ttaatggaaa aattggagcc
     1681 gtcgtcatta ctaaagaaga tttgggatta gagaatgttc tcacagaatt accctatgca
     1741 agtgaagaag atgacggcat tatcacggca gaaatgtatc aaaaaatttt aaacagtgga
     1801 gaaggtgact acgtgttgcc agttgccact atcgaccgtt tgggtggcat aaaagttggt
     1861 gaattattga cgattgatga gacagggaaa gtctctgcag tcagacaatc tgatgtcaat
     1921 ttttcgctgg agttaaaaga aaaactcgat tcactgaaaa attatactgc tggagaaaac
     1981 atcactattg atgaagatgg aacaattagt tctacaggtg gtagtgggac tggtggtgtc
     2041 aatcagtcat atgtagatca aaaattccaa gaagctgtaa atcaagcaga aaattacaca
     2101 aacgaaagaa ttccaaattt tacttttgaa aaaattgggg aggtatagag aatgacagat
     2161 atcgtaaaaa taaaacaaag caatgtacag gtttatccac aaactcattg gaatgctata
     2221 gaaggcaaac caacaa
//
LOCUS       DAZUJR010000179         2017 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.184, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000179 DAZUJR010000000
VERSION     DAZUJR010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2017
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.184"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            681..1868
                     /locus_tag="ACG804_002909"
     CDS             681..1868
                     /locus_tag="ACG804_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HFS4833770.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          644 a          334 c          394 g          645 t
ORIGIN      
        1 tcttgatgtg atatccttgt cttttttgta atgtttttaa cttattgctt ttgcaaaatt
       61 tatttacctg ttttctggat caacgatagt gtacattatg ctatccttgt ttggatttta
      121 ggacgtttaa agaggcactt ttttacataa cttaatccat agacctttta agcatgctgt
      181 gagataataa taaagaagag tttaaagcgc accccaaacc acttccccat aagtgtatta
      241 cgctttaaac tcttttatat ttgaattcac taagaagcat accatatttt tgaaaaaaag
      301 tgagaaaaaa ggcttataat taggatttag agtaattaat tagatgttta ttttatagga
      361 ctgatactat agattacaaa tagtatcgta tttcgcaatc ttaaaattat cttcttactg
      421 tgaataagat aataaaattt gtatttgtcc tttttaggta acttatttta atctatatac
      481 ctttctggat caacgaaagt atactttata tagtcataac gccgatggta actatgcact
      541 gtaacgataa tgctgctaaa atatcttttt acgattacgt ccatataatt gtgtaaaagt
      601 gaagcatcaa aaaagccatt gatctcagtt aggagtacaa tgttttttgc agaaaacata
      661 ctcgaatagg actgatatca atgactcaag tacattttac ttttgaaagc gaagaaattc
      721 aagcaattat aaacgaaagc ggtgcgaatg ataccgcaaa aacacttatg actatcatgt
      781 ttaatcagct gatggaagaa caacgaaatc aatatattca ggcaaatgcc tatgaacgtt
      841 cagaagaacg gcaatcacaa agaaatggtt actacgatcg ttcgtttaca actcgaattg
      901 gtacgttaga acttcatgtt ccacgaacca gagacggtaa gtttagtcct actatctttg
      961 aaagatatca gcgaagcgaa aaagctttga tcgctgccat gattgaaatg gtcatttctg
     1021 gtgtctccac tcgcaaagta actaaaacag ttgaactgct aacggatggt gcgactgttt
     1081 ctaaatcatt cgtttcaaat ctgatgaaac agttggatcc atttgttttt gagtggagaa
     1141 accggagcct agaaggctcg gaatatccat ttttcatgtg tgatgccctg tatatgaaag
     1201 taagggaaaa tcatcgtatt gtctcaaaag gtgtatatat tggtatcggc attgattctg
     1261 atggacgacg tacgattctt ggttttgatg ttcaagacgg cgaatcggaa gataattggg
     1321 ataccgtttt tcaatcgttc gttcaacgag gtttgttcgg tgtaaaactg gtcatttctg
     1381 atgcacacaa agggttagtt aaggctgttc gcaagaactt tttaggtgcg agctggcaaa
     1441 gatgccaagc ccactttttg agaaatattt ttgataagct gccaaagaaa gtttcttctg
     1501 atgtaaaaga cgagttgaag agtatcttta aagcctctga acttgaattg acacgtgaaa
     1561 gaaaagagca cttcttggaa aaatatggtt gtgattcaaa attaagtgct gcttgcgaca
     1621 ttttagaaaa cggctttgaa gatgctattc aaattttgtc ttttcctgaa aatatccgcc
     1681 gaaggattcg tacaaccaat gtgttggaac ggttgaacga agagattcgc cggagagaac
     1741 gagtgattcg gatttttcca aatatcaatt ccatcactcg gataattgga acacttttga
     1801 tggaaaaaga cactgagtgg ctggcttctc cacgaaaata tttagaattt aattcgaata
     1861 acatttagca ccatgaacct gtgcgagtct cttctttctg aggagagaca tcaagagtcg
     1921 ctgcgctact gctcctgacc tctctcctca gaaagaaagg catggcagtt aggttcacaa
     1981 cgcaaaacat tgtgcttttg atgaggttga actttta
//
LOCUS       DAZUJR010000180         1987 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.185, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000180 DAZUJR010000000
VERSION     DAZUJR010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1987)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1987)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1987
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.185"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(33..458)
                     /locus_tag="ACG804_002910"
                     /pseudo
     CDS             complement(33..458)
                     /locus_tag="ACG804_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
     gene            complement(567..1598)
                     /locus_tag="ACG804_002911"
     CDS             complement(567..1598)
                     /locus_tag="ACG804_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4833771.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
BASE COUNT          615 a          330 c          345 g          697 t
ORIGIN      
        1 ctctaggaaa aaattaacta gcaccacggg ttaggaatct gttttgattt tgttccattt
       61 gaaatttctc tcactcgctt ttttgtctca tcatcaaata aaatgaaagg gtcttctaaa
      121 cgatcgataa atacttccat tgttgttgtt ggtagatgat aagaagtcat gacaggcact
      181 gcaccaaggt aagacacaga aacagctaga aggtatgtgt caaaagcgga actcttataa
      241 ataataactt tgtctccgga tttcactcca agatgagcca attgataagc ccgtttcaac
      301 acactttcgc agcatttttt gtaagttgtt tcaagtccta attctgggaa agctgaaagt
      361 ggctcatcaa agataatcgg ggtctcggaa aagttagctg cagcttcttg aaaattcgta
      421 aataagttca aaggggaata cgttatggtc tccatcattc acactccatt atcttttgtt
      481 aagtaatata caaattcaag ataatcgtaa cataatcctt tatataataa catagtttat
      541 tgtgaaaaaa agatcataca tttgttttat atggaagaaa cccgaacgaa tgccgctaat
      601 tcgtgataag aaaaatcaac catcttttcc cagatatctt gaaaagaatg ggatgagagg
      661 tatcgattac cacataaata atttaccgcg tcagcatcat ctaaatatag ttctgcataa
      721 taacgatatg tttttctgca tagttctggc gatacgtttt tatatactgt aattttgctc
      781 aaaatttggc gaatagtccg aggagaaatt tgctgatcat gtgaggaacg aaaaacaaaa
      841 gaattttcgt ccgtattttg tgctgttaac ttaaaatagt tctccagaaa tggcatcgct
      901 tcttttggta ttggtacttt attcagtctg ttttcttttc tattcagatt aagaatctgc
      961 ttggtcaaag atacatcttt acgtttaagt tctactactt catggatctt taatccgcaa
     1021 tacagaagaa tggcagtaat tgcaaggttc ctcggtctat tcttttcttc aaagctagct
     1081 tctctgcttg tttgaaagcc ttcaatcggg ataaacaaat gctcaaaatc tttgaaaagt
     1141 tctgcatcga tatatcgcgg agctgctttg gttgtttccg gtaaacttgt acccaaaaga
     1201 gaaatctctt cttcaatcag tcctttttga tacaaaaatc gtaaaaaatg atttaatgaa
     1261 tattgcttcc ttgaaatccc gtaatagcta ttttcaaaca attgctccgt ttcttggttc
     1321 gctgtagttt ggaacgaacg agtatgtcga tagattttag ctaagaaatt ctgataatct
     1381 tgtttttcta aatggataat cagctgatca tccacttctt cagaaaatac ttttctcaaa
     1441 taatcagtaa acagatgaaa atcttttgcg tattcatagc gactgcctaa tgaaagggaa
     1501 gaacgatttt cttctaaaaa ctgttgaaag acggaaggga gcaagtgtgt acgttgcttt
     1561 aacttttctt gcagttgttt tctagttttg ctgtccatta caaattccct ccaatagtgt
     1621 tcattttcta tattttaccg catttcatca aatgaagata gacagtttgt cttgatctta
     1681 ggaagcaaat ttttaactaa gtactagcta aaagatatga agtaagaaga tacattttta
     1741 gttattttat tagtgcagtc attcttttga tcttttaatt gatttatcct ctttttagct
     1801 atgtggttac ttcatgagca atgaaatgga tttggttcgt tctaatggca ggaggctctt
     1861 tcttttattt ccgaaaaatt agaaaacatt ttttcagaat cgattggctc tccatttatt
     1921 caataatggt ttgtctaacg atattgttgg gataattctt aaagaagtat tagaaatagt
     1981 tggtact
//
LOCUS       DAZUJR010000181         1983 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.186, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000181 DAZUJR010000000
VERSION     DAZUJR010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1983
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.186"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(34..735)
                     /locus_tag="ACG804_002912"
     CDS             complement(34..735)
                     /locus_tag="ACG804_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFS4833772.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(751..1191)
                     /locus_tag="ACG804_002913"
     CDS             complement(751..1191)
                     /locus_tag="ACG804_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HFS4833773.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(1191..1766)
                     /locus_tag="ACG804_002914"
     CDS             complement(1191..1766)
                     /locus_tag="ACG804_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0009691 - cytokinin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HFS4833774.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
BASE COUNT          573 a          415 c          306 g          689 t
ORIGIN      
        1 aatttttctt tcccgtcgtt tggtttttta tttttagcct aattcttgac cttttgcatg
       61 ctggttatcc gtaaaatatt ttccagcagg ctttccttcc aattcagcta atttttcttg
      121 gatctgacgg atcacctttt ttgcatcttc tggattttct acaaaatcga atttatcccc
      181 atccacttgt attttaggac atacatcaaa atcttcatac cattgattat agcgggtgtt
      241 caacgtttca taataggtat ataacgtctc atcgctttct agctgttcat agtcacgccc
      301 acgttttttg atacgttcta gcatcgtgtc caaagaaact ttgatatgga ccatcaaatc
      361 aggccgtttt tttggagcaa catcatctaa ctcgtttagc atcgtatcta ataagctatc
      421 gtactgctgt acttcgatat ccgttacccg acctaaatca gcgtttagat ggaacaacag
      481 gctatcttca tagatggatc ggtctagcac attgtcatcg ttcactaaag catttttcat
      541 tgctaaaaat cgcttgttca aaaagaagat ttgcaataaa aaagcgtact gctcaggatt
      601 tgaataaaag agcggcaata cttcgttatc ttcgacattt tcataaaatg gtttagaatc
      661 aatctctttt gcaagcatat ccgtcaaact gctcttacct gcaccaatcg ttcctgaaat
      721 caaaatcact gacatacaac ccttcctctt ctataagtac tcgcctacgt aagtttcaac
      781 aggcaatgtt tcaaaatcat attcacgtac agcttggtct gattttaaat acgtatggag
      841 actttgtgta atcatcaagt tcgtaggtac cgtctcttct tgtacaatga tcatcggttt
      901 tttcaacata gttgccacac ctaattcgta agccgttcct ggatcgattg tttgatgctc
      961 aaagtcaagg atagcaacaa caaattctgc atttgtcagt tcttccatat ctttttcgta
     1021 tacttcctgc gcccatccag cgctgaatag ttcataattg ctttcttggt gatgacgtgg
     1081 agagtagaaa cttgtgactg ttttgttttc ctccaacgct ttttcgatac gacttactcg
     1141 atcgatttgc tcctctgaaa aaaatggtcc tgctaaatat atttgactca ttattttgcc
     1201 tccttcaata ataactgatt tttaatagat actgctcgta attcattgac cagttccaat
     1261 ggattgttgg aaaagattac ttgatccaac cattttttat ccataaaatc ctcttttgca
     1321 aaagtttcta ataattgttg caagccgctg taataaccgc caatattcaa tattccgatt
     1381 ggcttgtcgg gcgtcagacc gattgctatc caagaaagaa gttgtgagaa ttcctccaat
     1441 gtacctagac ctccagggaa aacgaggaca gcatctccct tttcaaataa taataccttt
     1501 ctttcatcga tcgtttctgt aggaataaat gtagtaacat cttttccagg caattcagtt
     1561 tcaaaaagcc cattcggata gatacctgtg acttttccgt tattttccag tactgtttta
     1621 ctaatcactc ccataatccc ggagtatgaa ccaccgtaaa ccagttcgat ttcttcttgt
     1681 gccatgtatt ttcctaacgt ttgcgcaata aatttgtaac tttctttatt accaaaacgg
     1741 gaaccgcaaa aaacagtaag tttcataaaa aaacactccc taactcaaaa gtctatcttc
     1801 attctacacg tgttttttta aaataaaaga ctagattttg tagtttttta gtggtatata
     1861 ggatagacgc cactatatat agtatttaga aaaaaatcat ttttcagcca ttttatagat
     1921 aaaacaaaaa taaataacgt gttttcatcg atatgaaatg acttacttat agaagatact
     1981 ggg
//
LOCUS       DAZUJR010000182         1979 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.187, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000182 DAZUJR010000000
VERSION     DAZUJR010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1979
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.187"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..367
                     /locus_tag="ACG804_002915"
     CDS             <1..367
                     /locus_tag="ACG804_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HFS4833775.1"
                     /translation="KKQIVPKEIETWWRIEMQLRRGKATDWHAMVRESLDSFASPHYL
                     PGDVKPVDRIMIKGLNQDHSEWAYISRNLKYRLRKLLKEESQNDELTNHLRETFKESA
                     NDLKIELDTWLLGLDVTEK"
     gene            567..749
                     /locus_tag="ACG804_002916"
                     /pseudo
     CDS             567..749
                     /locus_tag="ACG804_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313295.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1330..>1979
                     /locus_tag="ACG804_002917"
     CDS             1330..>1979
                     /locus_tag="ACG804_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFS4833776.1"
                     /translation="MANENQLSEIQSKIEGRGAEKRTTINQLEKLNRISNRRLSVDDK
                     VHPLKLSWSIDRITIVGKLNDTIAYWTQNGVVFVDFEQLMRLNENQGYLKSVGTNGWQ
                     LFDQYGEDIAYIEMLKFHPDKGRIDFNPNKIGEFLKGSMKQFIHDLFLDAHFSRADIA
                     CDILGVPDDFITQYRIVDPVSFKPIYGRSGKLETAYWGSRASERQVRMYNKKLEQER"
BASE COUNT          657 a          305 c          461 g          556 t
ORIGIN      
        1 aaaaaaacag attgtaccaa aagaaatcga aacatggtgg cgtatagaaa tgcagctaag
       61 acgtggcaaa gcaacagatt ggcatgcgat ggttcgggaa agtttagata gctttgcaag
      121 tcctcattac ttgcctggag atgtaaaacc tgttgataga attatgataa aagggctgaa
      181 tcaagatcat tcagagtggg cgtatattag cagaaatttg aaatatagat tgcgcaaatt
      241 gttgaaagaa gaaagccaaa acgatgagtt gacgaatcat ttacgagaga cgtttaagga
      301 atctgcaaac gacttgaaaa tagaattaga cacgtggctt ttgggtttgg acgtgacaga
      361 gaagtgatac cgaataagaa aagtcagatg agtgagagta aatttacgtc aatgtttaat
      421 gacgtgagtt tacgataagc gattattttg cgtgaagcaa aataaagcgt aaaaggagtt
      481 gagagcgtga cacgctttcg gctccttttt tcgttgtcac ttgtgacagc gaataccctc
      541 ggagagcatt tggaattgtg acagccatgt cacaattagg aaaatgttac tctttgtcaa
      601 agagtaacag aaaggtttac actcttttta ttagcgacag cgcgaaggag gggtttaact
      661 tggggtttag tatttcgttc aaaaagggaa caaagaatac aagcatttct cataataatc
      721 gtgagttaac tgatagccaa aaaatcaatg gtttgtctgg tagaaaataa ttagcagatt
      781 tacaagtggg aaataaaaag ctgaaagaag aaaattgcat ttcaaactac attttctaca
      841 atagctctaa aatggcatat tttgcgttct gagcggtttt agcgtttatt tcgtttagtt
      901 atcggcacaa tcgttaaaac acgttagagg agcgaaaatg gagcctgtaa ggcgactggt
      961 agcggaacga tcgtgttaga ttgtgaaaac cgatagctga atgaaataaa cagcgggtgc
     1021 gccctttcca tttcggcagg aggaggctca aggggttcgg ggaatgaaat tccctgaggt
     1081 ctttttattt ttttaggagg agtgctataa tcaaagaaaa cgagaaaaaa gagcaaaata
     1141 aaagccgagc agtgcgctaa cactctcgac tatttacgga aactacttca cctagctccg
     1201 taactcaggt tcattatacg aatattttta ggtttcttca agctagagat ttttggatat
     1261 gaatttttag ggttacgtga actctggaaa ttctttccaa aagtctcttt tttcgtctgg
     1321 aggacgaaaa tggcaaatga aaatcagttg agtgaaattc aatcaaaaat tgaaggtcga
     1381 ggggcagaaa aaagaacaac gataaatcag ctcgaaaaac ttaaccgtat ttctaacagg
     1441 cggttaagtg ttgacgataa ggtacacccc ctaaaattaa gttggtcaat cgatcgaatt
     1501 acaatcgtcg gaaaactgaa tgataccata gcttattgga cgcaaaatgg agttgtgttt
     1561 gtcgattttg agcaattaat gcgtttgaat gaaaatcaag ggtatttgaa gtcggttggt
     1621 acaaatggtt ggcaattatt tgaccaatat ggagaagata tcgcctatat cgaaatgtta
     1681 aaatttcacc ctgacaaagg tcgtattgat tttaatccaa ataaaattgg cgagttttta
     1741 aaggggtcga tgaaacaatt cattcatgat ttgtttctgg atgcgcattt ctcacgtgca
     1801 gatattgctt gcgatattct cggtgttcct gatgatttta ttacccagta tcgaatcgtt
     1861 gaccctgtgt cttttaagcc aatttatggc cgttctggca aattagaaac agcgtactgg
     1921 ggtagtcgtg ccagcgagcg acaagtgcgg atgtacaaca aaaagcttga acaggaacg
//
LOCUS       DAZUJR010000183         1918 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.188, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000183 DAZUJR010000000
VERSION     DAZUJR010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1918
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.188"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            274..840
                     /gene="amaP"
                     /locus_tag="ACG804_002918"
     CDS             274..840
                     /gene="amaP"
                     /locus_tag="ACG804_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HFS4833777.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            853..1041
                     /locus_tag="ACG804_002919"
     CDS             853..1041
                     /locus_tag="ACG804_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HFS4833778.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            1054..1611
                     /locus_tag="ACG804_002920"
     CDS             1054..1611
                     /locus_tag="ACG804_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFS4833779.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            1643..1885
                     /locus_tag="ACG804_002921"
     CDS             1643..1885
                     /locus_tag="ACG804_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFS4833780.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
BASE COUNT          705 a          295 c          395 g          523 t
ORIGIN      
        1 aaataaatag aatcttgtaa taataactga gcataatctt tgcaattttt aatcttgaat
       61 aatatccttt aagtatagcc agcaatcaaa agtaaataga gaataagtaa gcaattgtta
      121 tttcagtatc agactggcaa taaaacgccg ttatgatcca gcaatgtttg gtagcgcttt
      181 atttactgat gctatgctaa ctgttcgcta tctatactgt gattgtcggt agagttattt
      241 acagggtaaa aataagttta taggaggtgg aaaatgaata aggggttaaa aataatcggt
      301 gttatcatga gtttactgct actttcagta tttctagcga ttgcgttgat caatgcgccg
      361 tatattatgc ctgaacaatt ggaacgattt cgcttcttta ctttaacgaa ttactacatg
      421 caacaatata ttttctgggc agctgtagta tttgccgttc ttgctattat catcttgcta
      481 gtcgttcttt tctatccaaa gtcaagagga actttcgtta tgaaacggga agatggcaaa
      541 ctaacaatcg acaaaaaagc gatcgaaggg ttggtacgtt cccatttaca cgaagaagag
      601 ttcattcatt cacctaaagt acggatacgt tcaacgaaaa atcgaatcca tatccatgtc
      661 aacggagact tgaaacgaac ttcttcatta gtagggaaaa caggtgtatt gatgcaagat
      721 atcgaagaag aagtaactaa agtactcgga acaaaagaaa cggtcaaagt ggcagtcaca
      781 tacagcggtt atgaagaaca agaagataca agagactaca agcactctcg agtggaatag
      841 gagggccaaa taatgaaaga actattttca gcatacaagc tccctattat ctttgggggt
      901 cttggactac tgctagctgt tttatggtta acgattggat ttttcaagac attgttgatc
      961 ataatcatga cagcaattgg cgcaggaatc ggtttttatt tgaaacagtc aggaatagtt
     1021 gatcaatttt ttaaatcata ggaggaaaca aagatggaaa acaaaaacat gaatacaaca
     1081 aatggatcag ttttggcaaa tgaaaaagga gaaaaccgca tgatgaatgg tgaattgact
     1141 tatgaagaca aagtcatcca aaaaatcatc ggttatgcat tgaaagatgt agatggtcta
     1201 ttgacattag atggcggatt tttctcaaat atggctgaaa aattagtcaa cacagataac
     1261 gtaacagcag gtatcaatac agaagtaggt aagaaacaag tagctgtgga tctagatgtg
     1321 atcgtagaat acggtaaaga catcgaagat atttacaacc aaatcaaaga attgatcagt
     1381 actgaagtaa acaatatgac acatttagat gttatcgaag tgaatgtgaa tgttgcagac
     1441 atcaaaacac aagaagaata ccaaaaagat caagaaacag tacaagacaa agtaacagaa
     1501 gcagcaaaat ccacaggaca atttgcttca cgccaaacag ataaagcaaa atctgctgta
     1561 ggcaaaggtg cacaaaaagt caaagaaaat aacgaaccac gtgtacaata agaagtaaga
     1621 agtcagttag gaggaattta aaatgggatt tatttgggca ttaatcgtcg gcggtatcat
     1681 tggagcaatt gcaggagcaa tcacgaataa aggatcatca atggggatca tcgcaaacat
     1741 cattgctggt ttagtaggtt cagcaattgg acaagcttta ctaggaactt ggggaccaac
     1801 aattgcagga atggctatca ttccatcatt gatcggtgca atcattttag tattagtcgt
     1861 ttcattcttt gcacgtaaat tataagcaaa ttgaagaaaa acttatgttg aaatgaag
//
LOCUS       DAZUJR010000184         1915 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.189, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000184 DAZUJR010000000
VERSION     DAZUJR010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1915
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.189"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            66..139
                     /locus_tag="ACG804_002922"
     tRNA            66..139
                     /locus_tag="ACG804_002922"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:100..102,aa:Ile,seq:cat)
     gene            complement(654..953)
                     /locus_tag="ACG804_002923"
     CDS             complement(654..953)
                     /locus_tag="ACG804_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFS4833781.1"
                     /translation="MLFNETQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKDVYFLFDIVTDVLDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(959..1189)
                     /locus_tag="ACG804_002924"
     CDS             complement(959..1189)
                     /locus_tag="ACG804_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833782.1"
                     /translation="MMEEFIRKNISDEYADFYEQSNEKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
     gene            complement(1448..1561)
                     /locus_tag="ACG804_002925"
                     /pseudo
     CDS             complement(1448..1561)
                     /locus_tag="ACG804_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
BASE COUNT          645 a          307 c          303 g          660 t
ORIGIN      
        1 gataacaggt ttgttgccac acattctact ggttgattgt ttatggcttt atgtggcaac
       61 aaccagtacc cttagctcag ttggtcagag cagacggctc ataaccgtcc ggtcgtaggt
      121 tcgagtccta cagggtacat taacgtagcc atttgaatcg ttctgtgtta gaattttttg
      181 aagagtatta tacaagctaa agcttttctt cattgccact caaatgagtg gcttttttat
      241 gtatcctttt atggattaat gaaaggatgt ttcacatagt tatatttctg tatatttgaa
      301 aagttttact ttgattttta aatagaaaga catttgggtt atattgtgag ataataataa
      361 agaagagttt aaagcgttcc ccaaaaacca ctgccccata agtgtgttac gctttaaact
      421 cttttatatt tgaagccatt aaaaagcata ccatattttt gaaaaaaagt gagaaaaaag
      481 gcttataatt ggagtggtag ttaattagtg acttattttt gattttatag cactgatact
      541 ataaaatata gatatcatca tattacacaa tcttaatact aacttaaaaa atatctcctt
      601 tcataagtat ggtgataaaa tccgttccgg gctacctttt taggtagcct actttaatct
      661 ttgtatcttt ctggatcaac gaaagtatac tttatatagt cataacgccg atgatcgctt
      721 cgagcgtcta gcacatcagt cacgatatca aacaaaaaat atacgtcttt cttcattcta
      781 gttttcgcag cagggatttt aaagtagttc ttattagaat agtagagatt aattaataag
      841 ctatcttcga ttgctaaaaa gaaaacttct gaatcccaca ccttataaaa atctttgaca
      901 aatctattcg aaggatcaaa tttaaaccat aattgcgtct cattaaaaag cataaccatt
      961 actccgatct atttttaaac ttagtctcta cctctaatat atatcgagtt tttattttgc
     1021 cttcagagaa tactgtttct ttttttgcag ttacaggttg tttattttcg gaaaaagcta
     1081 atatagctaa aattgaaaca tccatctgga atttgtcttt ttcgttgctt tgctcataaa
     1141 aatctgcata ttcatcacta atattttttc taataaattc ttccatcata aagatcacct
     1201 cgaaaagagt atacgaacaa acgttctttt tgtaaaggtg gaatttatta tactaaataa
     1261 ataggtgaac aagtacttgt gccaaattat gtgccaaaaa aaatcgaatt taataaaaca
     1321 caaacaaaaa gaaatcctat tatgataaca tttcttataa taacaaacac aacagaagac
     1381 gtgtaatagt tagtcaggaa cgtacaaata acccctgtat cctttgcggt acagggggtt
     1441 attttgtata agtagacatt gtagtttcta aactgctatg tcctaaacgt ttcgatacgc
     1501 taagtatatt tactccttga taaagtaaaa tagatgcatg cgtatgtctt agtccatcaa
     1561 taaacagtcg aagagaaaat agggaaaaat tgattactaa agaaaaactt actaggtcga
     1621 cggtgtagtt gattttcata cttcaataga ttcgaattaa acgatttcga ttggcttata
     1681 ccagtcctat ccaacgaaag atatatcgtt cttaactcta gcggtataac ttgaagcttt
     1741 acgtaaagcc aatgggaatg aactggagat gactttttat tatttttagt aatagctgat
     1801 gggttaatac ttacaacttt ccttttcaaa gtaccatata aaaaaacggt ggggttgttt
     1861 agcgaaataa aggatctaag ccaatagctt agatccttta ttctatgctt tatat
//
LOCUS       DAZUJR010000185         1891 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.190, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000185 DAZUJR010000000
VERSION     DAZUJR010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1891)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1891)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1891
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.190"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..349)
                     /locus_tag="ACG804_002926"
     CDS             complement(<1..349)
                     /locus_tag="ACG804_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HFS4833783.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSP"
     gene            complement(350..1258)
                     /locus_tag="ACG804_002927"
     CDS             complement(350..1258)
                     /locus_tag="ACG804_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HFS4833784.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     IHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
     gene            complement(1258..>1891)
                     /locus_tag="ACG804_002928"
     CDS             complement(1258..>1891)
                     /locus_tag="ACG804_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFS4833785.1"
                     /translation="SSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRN
                     FFVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHET
                     GIVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMH
                     DNNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
BASE COUNT          632 a          331 c          209 g          719 t
ORIGIN      
        1 aaggtgaagt caaatctaaa tctataatta aatcaaatat attatcttct ctttctagtt
       61 gtaagaatga atcacgtatc acttcaattt tccctacagt atctgtagct aattcaggtt
      121 tacgttctac aattttcaca gacggattta acttagtcgt caattctact aactcattac
      181 tgtccgtatt caaacaagtc gtgcaattat gttcaggatg tttttgttga tagatatcta
      241 tcattgctaa agcgaaatgg actaggggct ttcctgccaa atatttcaaa tttttatttt
      301 taaacccctt agacccagct ctaccacaaa tagtaaataa aatttccatt tatttctcct
      361 cagctatttt caatacttcg tttgcatgat ataaatcatt ccagttttct ttgcctgtta
      421 ctacgttttc aaagaaatat ttcaactcct tctcatacat atcattagca gattcaggca
      481 tttctttaac aatgttttct tcaaaactta ttttattatt taataagtca acattgatac
      541 attcatctaa agtaaacaat tgaaattttc ttgtaggaac tcttccaaaa taatctaaat
      601 gaatttctat aattttatca tcgtatctca atatatatgt tgctaaatca ttactgttaa
      661 tttcaagatt cgaatattta ccaaactgtt tttttactga tttagggaaa ccaaataggt
      721 ttataatata atccaattca tgtatacagt ctaattctac tcctcccccc atagatttaa
      781 aggcagaata attatttcta taatcagtac cttttctcca atcaggaaga taagtagaac
      841 aaatagctct tacagaatat acttttttac tttgaatact attacgaaca acttccatga
      901 tatttttata cctcagtgga gcagcaacat aaatattttt gtaatcataa ttatattgag
      961 taagatcaat actctcagaa aaagcaggtt tttctaaaaa tatgtaatca actttttcaa
     1021 caattacatt tagtgtttcc agatgcttaa aagtcggatt tgtaataaaa gctatatcat
     1081 aatgtgtatc caaatcgtct ctattttgaa tatacgttat ttcttcaaac tctttttttc
     1141 cactgctact ataagctgtt atatcaaaat taatagaatt cttttttcca tagcttatta
     1201 gattttttag atgtctcttt ccaattgacc ctaacccaaa aaaaattact ttcatcatta
     1261 atttacctca atgtcgttaa ttaagttaat aatatactta tctttttcaa aagtatattg
     1321 gggttccatt ttcttttcca aaagcgtgaa aaattcttta atctcctcta aatatgcatc
     1381 ttcaataata gtatgtgaat aattattatc atgcataacc tcatcgtaca attgaatatc
     1441 tgtcatacta gaagtttctt cattccatga aaatagagaa tccgggttac cttcccattc
     1501 tattaaaatc ttttcaccaa ttatagttaa atttctttta gctactcttg aaacaacatc
     1561 tacacttaaa gttccaacta taccagtttc atgctcaata ataagagtga aactgtccga
     1621 ataatcaata tcaagattgg ataatttctg ggtcattaca gtaaacgatt taactttccc
     1681 aaatgtatct ataatccaag gtaattcaat agcgaatatt tctctacacc cattagtttt
     1741 tttgtttgaa acaaaaaaat tgcgataatc ttcccaagga tgccagtcgg gtaaatactg
     1801 tcctacatgg tattgataag aaattttttt attatgcgtc actttagact taatatattg
     1861 aatttctttt ctcttcaaaa atgtagaaga t
//
LOCUS       DAZUJR010000186         1854 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.191, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000186 DAZUJR010000000
VERSION     DAZUJR010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1854
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.191"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(140..1288)
                     /gene="tnpB"
                     /locus_tag="ACG804_002929"
     CDS             complement(140..1288)
                     /gene="tnpB"
                     /locus_tag="ACG804_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element RNA-guided
                     endonuclease TnpB"
                     /protein_id="HFS4833786.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSS
                     GKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQ
                     RKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDI
                     ICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICS
                     ECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
     gene            complement(1305..1709)
                     /gene="tnpA"
                     /locus_tag="ACG804_002930"
     CDS             complement(1305..1709)
                     /gene="tnpA"
                     /locus_tag="ACG804_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HFS4833787.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKE
                     MFWSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
BASE COUNT          551 a          329 c          299 g          675 t
ORIGIN      
        1 taaacctgac ggttcttaac gcttgaagtg ggagcttctt gggaatagag catacttgat
       61 agcgtatttc tttactaaca gcggtgtctc ttatttacca agctatcccc gtagttccta
      121 cggttcttga tgattggatc taagccaatc ccatagaatg tagtcttaga ccttcggtca
      181 gaatattgat actagcattg atatcacgat catgatgagt atgacaaaca ggacaagtcc
      241 attctcgaat ttcaagagat ttcttgccat ctttatgtcc gcactctgaa caaatctgac
      301 tagacggaaa ccatttatct actttgatga tttttcgtcc ataccagtca gccttgtatt
      361 gtaatttagt cacaaacttt gaccaagaaa catcagaaat acttttagct aatttatgat
      421 ttcgcaacat accttttgtg tttaagtctt caatacagat aatatcgtga tttttgatca
      481 tttctgtact caacttattc agaaaatcag tacgttgatt cattactttt tcatgcaatc
      541 tagctacttt gcgtttttgt ttttgataat ttttagcttc aaatagattg gtacctttat
      601 ttttagccaa taaagcacgc ctagacaatt tgcgttgttc acgctttagt ttcttttcca
      661 ttttggacgt gaatttatta ttatcaattt tttgtccatc agaaagaatc gcaaagtcca
      721 taatacctaa gtcaatacca attgtggaat tagttttagg taattcgata atttcttctt
      781 tacacaacaa agaaatatag tatttaccgc tagaatgacg tgatattgta gcagatttga
      841 taatcccttt tggttgtcta tgaagcttaa ttcttactaa tgacttcaat ttaggaactt
      901 tgatgaattt actatcaatc aaagcaactg taccattttg attattcgtt gtataactct
      961 gaacaggatt tttcttactt ttgaaacgtg gaaatccaac ggatttatcc cgaaaaaaat
     1021 tcttgtatgc tttatctaaa ttaagttggg cattggctaa agcaaggcta tcaatttctt
     1081 tcaaaaacgg aaattctttc ttgtatttag ctggtgtcgg aaaagtcatt tttttagaag
     1141 aatcattttt aacttcttca tacgcctttt ttcggtcatc aagcattaga ttgtagacct
     1201 tacggacaca accaaaagat ttggcaaaga agatttcttg ttcctctgtt ggatagattc
     1261 tgaatttgta tgcttttagt tgttccataa agttcaccta ctttctattt atgattgttt
     1321 ccttgatttt ggatatactt cttaatcaca tcaattggtg cgccaccagt tgtcagaaga
     1381 caaaaacttt tagaccagaa catttctttc caaagaaatt gtttgactct tggaaagtca
     1441 cgttttatca atcttgagct ggcactttta taggcattga tgaattttgt caattctgtt
     1501 ttaggttgag ctttgaacat aatatgaacg tggtctttat catgattcca ctccactaaa
     1561 gtaatgtgat acgattctga aattctttca aaagtagttt tggcataatc agatatttca
     1621 tcatcaatca cttgtctacg atatttcgtt actaaaacaa ggtggtaata aagaagaaat
     1681 actgaatgat tatttgtatc taattccatg ttatatcaac tcatttcttg tatagactga
     1741 ttgtaacatg gaacaaaata aaaaggcaat acgccttagt tgtcggtctt cgagttacca
     1801 acggtaaccc tcataccgaa cggcattcat cacccaccta tagaggatgg gcga
//
LOCUS       DAZUJR010000187         1722 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.192, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000187 DAZUJR010000000
VERSION     DAZUJR010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1722
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.192"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..262)
                     /locus_tag="ACG804_002931"
     CDS             complement(<1..262)
                     /locus_tag="ACG804_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HFS4833788.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAI"
     gene            complement(280..600)
                     /locus_tag="ACG804_002932"
     CDS             complement(280..600)
                     /locus_tag="ACG804_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4833789.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            899..1675
                     /locus_tag="ACG804_002933"
     CDS             899..1675
                     /locus_tag="ACG804_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HFS4833790.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
BASE COUNT          636 a          286 c          281 g          519 t
ORIGIN      
        1 gaatagctat tttatctgct tctgtttcaa attttgagtg aaaagttgta gaagtatcgt
       61 acaaaactga aaattcaaaa tgagaggcgc tgaaatgtgc aagttcatga gataaatgaa
      121 aggcttctgc agtttcaccg tatagatttt cattcaaaaa aatgattctg ggttttggat
      181 agtagaaacc aggctctttc atctccatat aaactacttt caaattgtat tcgctcaaca
      241 tttctttcaa tttcaaatac atacaaacca tcactccaac tattcatttt cctctaaagc
      301 tttagcaatt gcaatcgctt tacgcattgt ctccttagat atttcttttc catcaaaaga
      361 aaaaacagta tcgtcttctg ataaatccac atgtttaggg gtttctcttt cttctctacc
      421 tagaaggtag tctacagaga catcgaaata gtcagcaatc cgacttaatt catctgaatt
      481 aggagtatta tttttccact ttgctagata accgttagaa tatccaaaat taatttctaa
      541 ctgccgtata gatatctttt tcctcttcgc caagtctttt attatttcat aggtattcat
      601 cgataaaaca acctttctaa atgtttacaa aaaaagttta gaaaaatacg cagaaataat
      661 ttgactaatt ctgagtaatg agctatacta tatcttgtaa acagatttaa caactaaaaa
      721 gacaacaaaa aacactattg atatgtaaat gcagaccgcc aagaaagctt taaaatcaat
      781 gtttttatgt cttatttaat tatgctctta gtatagagta ttactcagat actgtcaatt
      841 gaatttagaa aaaagttgtt aaatttgttt acgaatataa aagaaaggaa tgagaaatat
      901 gaacacaccg caaattttta atttcgaaca aaacgaagtt cggacaattt tagtaaatga
      961 tgaaccatat tttgtaggca aagacgttgc gagtgttttg ggttattcaa acactaaaga
     1021 tgctttgtcg cggcatgtag atttggaaga taagatgggg tcgcgaatca cgacctcagg
     1081 tcaatcaaga gagatgacaa tcatcaacga atctggtttg tacagtttaa tcttaaaatc
     1141 aaaacttccc tctgccaaaa aatttaaacg ttgggtaaca agtgaagtgt tgccagcaat
     1201 tagaaaacat ggaggttatc taactccaga aaaagtagaa gaagctttgc ttaatccaga
     1261 tacaatcatt caattagcaa ctcaactaaa agaagaaaga actggaagat taatcgcaga
     1321 acaaaagatt gcagagtacg aacctaaaat ctcctattta gatagcatat tatcttctac
     1381 agattcagta acaattagtc agattgcagc agattatggg atgtctccac aacagatgaa
     1441 taaattactt cataaactag gtattcagaa aaaagtcggt aaccaatggt tattgtgcaa
     1501 aaaacacatg aaccaaggat acacaaaatc tcatacaact gagatcccga aagccgatgg
     1561 tggcactaaa attgtaatga ataccaaatg gacacagaaa gggcgtctat ttatctacga
     1621 attactaaaa aaagaaggat attaccctca aatggattta gaggaaattg gttagaaagg
     1681 agttttagta tgactgacat tgcagaaatc actcaacgag at
//
LOCUS       DAZUJR010000188         1703 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.193, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000188 DAZUJR010000000
VERSION     DAZUJR010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1703
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.193"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            200..742
                     /locus_tag="ACG804_002934"
     CDS             200..742
                     /locus_tag="ACG804_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833791.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            898..1347
                     /locus_tag="ACG804_002935"
     CDS             898..1347
                     /locus_tag="ACG804_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="HFS4833792.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMPDGMATLFLTKIIRCCECCGVMATIALDNEHPRI"
     gene            complement(1377..>1703)
                     /locus_tag="ACG804_002936"
     CDS             complement(1377..>1703)
                     /locus_tag="ACG804_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFS4833793.1"
                     /translation="GKEFDNQTIHEILNGFGITRSLSRKGCPYDNAVVESTYKSVKVE
                     FVHQYQFETLAQLRLELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSD
                     TSGEAA"
BASE COUNT          640 a          245 c          326 g          492 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tctggatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccagatgg aatggcaaca
     1261 ctttttttga caaaaattat aaggtgttgt gaatgctgcg gtgttatggc tacgattgcc
     1321 cttgacaatg agcatcctcg gatctgattt tctccggcag aagcacaatc attcaattac
     1381 gctgcctctc cagaggtatc agatccgcgc tcattatcaa ggattcgctt cgccaatctc
     1441 tgttgtcgaa tttggatcgg tgtttcatac gccaacgtgc catgtaagcg tagatagttc
     1501 caccaatgca cataatcaaa caattctaga cgtagctgtg ccagtgtctc aaattggtat
     1561 tgatgcacga attctacttt gacagattta taggttgatt ccacaacggc attatcatac
     1621 ggacaaccct tcctactcaa tgaacgagta attccaaaac cattcagaat ctcatgaatg
     1681 gtttggttat caaattcctt tcc
//
LOCUS       DAZUJR010000189         1677 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.194, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000189 DAZUJR010000000
VERSION     DAZUJR010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1677
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.194"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            64..972
                     /locus_tag="ACG804_002937"
     CDS             64..972
                     /locus_tag="ACG804_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HFS4833794.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKIKYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FDRWREEQENSFQDWREGQESDYLSWFESIKDILKSIDPGGVMLAELMDARVDLQGVR
                     HESISERFLSDLNYLYQKMKAALFTIEYGEIEVTDILQDDLFSDNHEVEKIETVEFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            972..1589
                     /locus_tag="ACG804_002938"
     CDS             972..1589
                     /locus_tag="ACG804_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833795.1"
                     /translation="MVKVKRMMETDESGVKRQFMPITHVSAVLGLEKMISGQSKVLSV
                     NGKYGAVILTKADLGLENAITELPYASETSDGILTAEMFQKIVNGEGGTYILPIATPE
                     QLGGIKVGELLEVTEEGVLSATKQTDFNFSEELKGKLESLKILKAGANISIAEDGTIS
                     STGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
BASE COUNT          620 a          226 c          348 g          483 t
ORIGIN      
        1 cagtattata gtgcaagtgc aatttcttcc attgtcatac caccaaaata gggaggtgat
       61 ttaatggcaa agtggaatgt catattaagt acaacagaac cctataatta cgtggggatg
      121 attcaagttc gacaaggcaa taaaaacact gaagttatgg aagctacaat tgtcgaaaat
      181 ggtcttccat atgatttatc agaatgtaag gtatattttg aatcagttgt tggcggaaaa
      241 tatccagtcc aattagaaac aaaaattgtg gatgctaaaa aagggaaaat caaatatatt
      301 tttgataaat attccatgca gtgtttgcat cgacaaacag ccaatttcat tatatttaaa
      361 ggagaagact tgattggaac aactcaagac ttctcttatt ttgtcatcaa tgctgtttca
      421 aaaacagaag gagaaatggg ttcttattgg caatcaattg aagatttaat tgctgatatg
      481 acagatttta ttaatgaaaa taaaggcgat tttacggact ggatgaatga aaggaaagaa
      541 gaatttgatc gctggagaga ggaacaggag aatagtttcc aagattggag agaaggacaa
      601 gaatcagatt acttgtcatg gtttgaatca atcaaggata ttttgaagtc tatcgatcca
      661 ggtggagtaa tgttagccga attaatggat gcacgtgtag atcttcaagg tgtacgccat
      721 gaatcgattt ctgaacgttt cctatccgat ctaaattatt tgtatcaaaa aatgaaagca
      781 gcacttttca cgattgaata cggtgaaatt gaagtgactg atattcttca agacgatctc
      841 ttttcagata atcacgaagt cgaaaaaatt gaaacagtag aatttccaat tgaagaagga
      901 gctttgatta ttgcaactgt tgatgatcca aaacagaatg ttttcactct tgagaaagtt
      961 ggggtgattt gatggttaaa gtaaagagaa tgatggaaac tgatgaatct ggtgttaaac
     1021 gtcaatttat gccaattaca catgtctctg cagttttagg cttagaaaaa atgatatcag
     1081 gacaatcaaa agttctttcg gttaatggta aatatggtgc agtcatttta acgaaagctg
     1141 atttaggatt agagaatgca attactgaac taccttatgc aagcgagaca agcgatggta
     1201 ttcttactgc tgaaatgttt caaaagatcg taaatggaga aggtggaaca tatattttgc
     1261 cgattgctac tcctgaacaa ttaggaggta taaaagttgg ggaactctta gaagttactg
     1321 aagaaggtgt tttatctgca actaagcaaa cagacttcaa tttctctgaa gaattaaaag
     1381 gaaaattaga atctctaaaa atattaaaag caggtgcaaa tatatcaatt gcagaagatg
     1441 gaacaattag ttctacaggt ggtagtggga ctggtggtgt taatcagtca tatgtagatc
     1501 aaaaattcca agaagctgta aatcaagcag aaaattacac aaacgaaaga attccaaatt
     1561 ttacttttga aaaaattggg gaggtataga gaatgacaga tatcgtaaaa ataaaacaaa
     1621 gcaatgtaca ggtttatcca caaactcatt ggaatgctat agaaggcaaa ccaacaa
//
LOCUS       DAZUJR010000190         1664 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.195, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000190 DAZUJR010000000
VERSION     DAZUJR010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1664
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.195"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            131..505
                     /locus_tag="ACG804_002939"
     CDS             131..505
                     /locus_tag="ACG804_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFS4833796.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="ACG804_002940"
     CDS             complement(619..1248)
                     /locus_tag="ACG804_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFS4833797.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="ACG804_002941"
     tRNA            complement(1382..1454)
                     /locus_tag="ACG804_002941"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
BASE COUNT          584 a          240 c          283 g          557 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt actt
//
LOCUS       DAZUJR010000191         1660 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.196, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000191 DAZUJR010000000
VERSION     DAZUJR010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1660
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.196"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..553
                     /locus_tag="ACG804_002942"
     CDS             <1..553
                     /locus_tag="ACG804_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833798.1"
                     /translation="IKKIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGY
                     GIDETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSST
                     LLISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRL
                     SEEKILLPENWAELRKLVEYGII"
     gene            540..>1660
                     /locus_tag="ACG804_002943"
     CDS             540..>1660
                     /locus_tag="ACG804_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFS4833799.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNIL"
BASE COUNT          548 a          214 c          266 g          632 t
ORIGIN      
        1 tataaaaaaa attcccaaaa tagatgaaaa cagtaaattg atgaaaaaca tacaatcaat
       61 ctttgggata gaagaagttt ttgtcggaga taaatgtatc ttttttgatc aacctttatt
      121 atctgatggt tatggcatag atgaaacaga tattttcgct aaagtaaata gtatattttc
      181 tggaaaaaaa gaaactttaa ttaagcttca tcctagagca aggacaaatc gttatggtga
      241 aaaaaacata ttgaattcca gtttaccgtt tgaagtcttg ctacttgaaa atgacttctc
      301 ttcaacactt ttgattagtc ctatatctac aatttctttt tcaccatcta tgatgtttga
      361 aaagacgatc aactctatta tgttggctaa attaatttta aatgaatata cagcattatc
      421 tgaagataaa aaagaaacat tgacaaatat tgttcttttc tgtgaacatt ataaccgtct
      481 atcagaagaa aaaattttac tcccagaaaa ctgggcagaa ttaagaaagt tggtagagta
      541 tgggattatt taacacactt tccaagtcaa aattagttaa gtccagtttc tggtatacta
      601 tagggaattt ttttattaag ggaatttcat tcataactat tcctattttt gtaaatatta
      661 ctactcaagc agaatatggt ttgattaata atttcacttc atttgtatca attttttcga
      721 ttcttgttgg gctaagccta aattcggcaa ttaataatgc aagttttgac tataaagatg
      781 acataaatga atttatgtca tcggtacttt ctctagctac actttcgtta attgtgttct
      841 tattaatagg gaacatatat tttttgtttt caaatgcttt ttttgatatg aaccaacttg
      901 tatttaattt gatgttatta caaagttttg ctagttttgt aattagttat atccagtctt
      961 attttacgat taactttaac cattttaaat atttgatttt atcttttata tctacttttt
     1021 tgaatattgc aatctctgta gctttgatgc agacattata ttttgatgat aaatatgttg
     1081 gcagagtagt cggcggaaca ctgtcatttg tgttgatagg tttagtaatt tatttaagaa
     1141 taatgataaa gggtgctcat ttttttgata aaaaacagtg gagatacgct ttaaaaatct
     1201 ctttgccgct aatcccacat tccttagcaa atatagtttt agcacaattc gatagaatta
     1261 tgattaattc ttatttaggt cctgctgcgg ggggaatata ttcctacatt agtaacatag
     1321 gtattattct aagcgtaata tggatgtcta ctaataacgc ctgggttcca tggttctatg
     1381 gtgagatgag taaaaataat gaaaaaaaag tgaagaaagt tagtaactat tatttagtag
     1441 tctttacttt gattacgatg attgtaatgg tagtttcgat tgatttagca aaatttatgg
     1501 ctccgaaaga ctattattct gggttatctt tagtggttcc gataacctta ggctatttct
     1561 ttcagttttt atatagttta ccagttaatg ctgaatttta tgagaaaaaa acatcgttta
     1621 ttgcgattgg tacagtagca agtgctatag ttaatatact
//
LOCUS       DAZUJR010000192         1639 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.197, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000192 DAZUJR010000000
VERSION     DAZUJR010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1639
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.197"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            415..>1639
                     /gene="ltrA"
                     /locus_tag="ACG804_002944"
     CDS             415..>1639
                     /gene="ltrA"
                     /locus_tag="ACG804_002944"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFS4833800.1"
                     /translation="MRRPQKTRKLGYHQRASVEHEGYDEVRSTSCGEQRKQDGVENLF
                     GRILDRNNLNQAYLQVVRNKGAAGADGMTVDQLLPYLKEHREELLSNLRQGNYKPQPV
                     LRVEIPKPNGGVRKLGIPTVIDRMLQQAINQVLQPLFEPEFSDNSYGFRPNRSAHDAV
                     KKAKSYYEQGYRYVVDIDMKAYFDTVNHDKLMYFIERKVKDKQVLKLIRQYLMSGVME
                     NGLITTTEEGTPQGGNLSPLLSNIYLNEFDQVLENLGHKFVRYADDCNIYVRSKRAGQ
                     RVMKKSIQFLEEQLKLTVNREKSAVGSPLKRKFLGFCILPTKKGIKIRPHAKAKQRVK
                     SKLKQLTKRNRGRSIQLILKEIKQLMTGWINYYGIGEMKEFMRELNGWLKRRIRQYIW
                     KQWKNPRTKRKNLIRL"
BASE COUNT          585 a          299 c          388 g          367 t
ORIGIN      
        1 acttggtggt gaaagtccac tacaggcttg gcagtaggaa ctgttagcga aagacaaggc
       61 ggcaatcgtg aggttgtggc tgaaggaagt cggacgcaaa ctcctgaact gacgaacaga
      121 aactagatac aaggctgaat taggtcggat aagtcttcat cacaagacaa agtccaatac
      181 tgcccgaaac ctatacagta aatctagcag ttacatggga ggaaagtttt cactcttacc
      241 gggggagatc tcatgagggt gttgtgggcg ttgaatgaaa acaaaccagc acaacgatca
      301 tggcgacatg atggtgaatc atgagaagtc agccgaggtc atagtagtaa cgacactgac
      361 cgttacgaag gactgaacaa taagaatctt gaataattta ggaggtgtga gaagatgcga
      421 cgaccgcaga aaacaagaaa acttggctat catcaaagag ctagtgtgga acacgaaggg
      481 tatgatgaag tgcgcagcac ttcttgcggt gaacagagga aacaagatgg tgtagaaaat
      541 ctgtttggga gaattctaga tcggaataat ctcaatcaag cgtatcttca agtagtcaga
      601 aataaagggg cggctggtgc agatgggatg accgtcgatc aactgcttcc ttacttgaaa
      661 gagcaccgcg aggaattact atccaattta cgccaaggga actataaacc tcagcctgtt
      721 ttgcgagtag aaataccgaa accaaacggc ggtgtaagaa aactaggaat tcccacggtt
      781 attgatcgta tgcttcaaca ggcaatcaat caagtgttac aaccgctatt tgaaccagaa
      841 ttctcagata atagttatgg gtttcgccca aatcgcagcg cacatgacgc agtgaagaaa
      901 gcaaaatctt attatgaaca aggttaccga tatgtggtgg acattgatat gaaagcctac
      961 tttgacaccg taaatcacga taagctgatg tatttcattg agcggaaagt aaaggacaaa
     1021 caagtcctaa aactgatccg tcaatactta atgagtggtg taatggaaaa tggactcatc
     1081 acaacaactg aagaaggaac gccccaagga ggcaatctct ctcccctgtt aagtaacatc
     1141 tacctgaacg aatttgatca agtgctagaa aatctaggac ataaatttgt tcgatacgcc
     1201 gatgactgca atatctatgt tagaagcaaa cgagcaggac agcgtgtgat gaagaaatcc
     1261 attcaatttc tcgaagaaca actaaagttg acggtaaatc gagaaaagag tgcggtagga
     1321 agtccattga aacgaaagtt tcttggattc tgcattctgc caacaaagaa aggtattaaa
     1381 attcgccctc acgcaaaagc aaaacagcgt gtgaaaagca agctcaaaca actcactaaa
     1441 agaaaccgtg gaagaagtat ccaacttatt ttaaaagaaa tcaagcaact aatgactggt
     1501 tggatcaact actatggaat tggtgagatg aaagaattca tgagggagtt aaacggttgg
     1561 ttgaagcgaa gaatcagaca atatatttgg aaacaatgga agaatccaag aaccaaaaga
     1621 aaaaatctga ttcgtttag
//
LOCUS       DAZUJR010000193         1610 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.198, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000193 DAZUJR010000000
VERSION     DAZUJR010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1610
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.198"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            7..267
                     /locus_tag="ACG804_002945"
     CDS             7..267
                     /locus_tag="ACG804_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833801.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVIGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(629..868)
                     /locus_tag="ACG804_002946"
     CDS             complement(629..868)
                     /locus_tag="ACG804_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833802.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            1154..1468
                     /locus_tag="ACG804_002947"
     CDS             1154..1468
                     /locus_tag="ACG804_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833803.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT          553 a          219 c          282 g          556 t
ORIGIN      
        1 tgaaatatga ataacgaaac tatcatttta ggaaaaaaat atatttgcca acctattggc
       61 ttgaaacaaa aagtgattgg agaagtaatc agtaaattag aaaattgtgt tgtgatctgc
      121 gtagacgaat atcatgacgt cgatcgcaat gaaatattag aaaaatgcgg aaaagtagtg
      181 gcaaaatata ctcacgttta tgagttggaa acaacagaat atctatataa ctatagcaac
      241 aaatatgaac atactttagt ttcataaaga tttaaataaa gtgccttcaa aagcgagaag
      301 accaagcttt tgaaggcact ttatttagtt ggcagtgatt gttcatgatt tttgatttat
      361 tcaaaaggtt cgcctagaga atctgtctct gtaacgaggc ctggtggaga aactcgataa
      421 aaacctatac tgccagaact gtcctatttt cggatagaca aactagtagt tttaaaaaga
      481 tcatccgatc caatcatttc aaaaaatgca aaactgatat caggatcatt tagctcaggc
      541 ttgttatcgt aaagcatttg taaaggttgc atttagttag gagtaaacgc gaaactatca
      601 tcattatttg ctgaagaaga tgaagaagct aattcagagt ttgtttgaaa taaaggagac
      661 gtgctgacag tttctttacc ctgttttttg cagaggtaga aacttttata tcggaagttt
      721 ctaccggaga atttttctca tttgtagaaa ttgttgaatc gatactattc gaaatttgcg
      781 tatctgaagg tatgttcttt gatgcagaag tcccacaagc agtaagtaac aataaatttg
      841 ataaactgat aaacagaatt cttttcatta tgtacacact ccttatagta tcgtttagca
      901 tacacctatg ctcagtatta ggcaaaatca atgcaaaact atcaagtctt ttatagtatc
      961 tattagtctt agtaatacat atatggagag ggtgatatcc cagttcaaac cagatacatt
     1021 ggttaccatc tgtattaacg attatgcctc taaacgcttt ttttatgaaa aaatttataa
     1081 gtgaaaacgt aggtatgata ttatctagag gtaatttttt tgggtattta aatagttgct
     1141 aggaggatag cttttggatt tttacagtaa ttttatctta ataatagcaa tattattact
     1201 tctaaatatt tggttttttg ataagagtag aaatgcaggg ataggtttta gaaccaaacg
     1261 aagtacgtct tctgaaaaaa agtgggtata ttcacagact attttttacg gaggggttat
     1321 ttcaatcagt ttactttctt caacacttta ttcttttaat gttatagacg tttccatgtc
     1381 aaattttata tctattattg gaatccttat ttctgcaatt attacacaac tacttcttgt
     1441 gtttgaagag aagtcaaaaa ataattaaag caattatgcc ttttagtaca ggaattatta
     1501 cttcttacaa atgtatagcg aatgtgaagc ctgctgtttt aattgttcta gaaaaacttt
     1561 tgagtgaaca attattttat gttaggatga attaatttct ctagagttta
//
LOCUS       DAZUJR010000194         1421 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.199, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000194 DAZUJR010000000
VERSION     DAZUJR010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1421
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.199"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..382
                     /locus_tag="ACG804_002948"
     CDS             <1..382
                     /locus_tag="ACG804_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HFS4833804.1"
                     /translation="ELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENEVTIVNKSR
                     YTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDIDSEEDFKWL
                     EFLFPKFLEDSSELQDIYNYLYRR"
     gene            387..1334
                     /locus_tag="ACG804_002949"
     CDS             387..1334
                     /locus_tag="ACG804_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HFS4833805.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT          480 a          201 c          286 g          454 t
ORIGIN      
        1 agaattaata gatgaacatc taaaaaattt agataaagac gtctactttt cagttgtttc
       61 tgcaagacgt aatccctatt ttaatatggt aaaaagaatt gaaaatgaag ttactatagt
      121 taataaatca agatacacat ctaggcaaca gacacctgaa gtttttgaaa tgaatgcctc
      181 aatgtattct tttaaacctg aatttctaaa aaaaagtaat tatatttttg atgggcaatg
      241 tgggataata aaaatgagag attatctaat tttagatatt gatagtgaag aagattttaa
      301 atggttagaa tttttgtttc ctaaattttt agaagattct tcggagcttc aagatatcta
      361 taattattta tatcggaggt aaaaggatga gctgttatct tatcaccggt ggggctggct
      421 tcattggttc taccttagcc aatcatttag gagaagaaca tgtggtaatc gtcgtcgatg
      481 acttatcaat gggaaaagta gaaaatcttg atatgacgaa aaatatcact tttattgagg
      541 gagatgtcgc tgagaaatcc ttgatggaag agatcatgaa agctaataaa tttgattata
      601 tctttcattt agcagcagtt gctagtgtgg cagattcagt tgcccgacca gtagaaacac
      661 atcgtgtgaa ttttgaaagt gtattaatga ttttagaatt gatccgcaag tatcaacctg
      721 atttaaaacg gatcgtgttt agttcttcag cggctgttta tggggatgaa ccgactttac
      781 caaaaaaaga agagtccgtg attcgcccat tgacgcctta tgcggttgat aaattcgctg
      841 cagaacaata tgtgctagat tattgtcatt tatatgatgt acccggtagc gcagttcgtt
      901 ttttcaatgt ctatggtcca aatcaaaatc cgaattctcc atacagtggt gtgatttcta
      961 ttctcgtaga tcgctataag aaacaaatcg taggagaagc aacttcattt acattatttg
     1021 gtgatggaag ccagtctaga gactttgttt atatagatga tgtaatccaa gcattacttt
     1081 tagttgcgaa tgaggaagct gcactgggga aacaattcaa tgttggaacg ggtaaagcaa
     1141 ccacactttt ggaattgatt catgcaatca atgaaattct cggtgtagaa ttgacacttg
     1201 aatacaaaga agagcgttcg ggtgatatcc atgactctct agcagatatt actaagatcc
     1261 agtcaattgg ctatcaaccg aaatatggta ttttaagtgg aatgactaat tatttgaaaa
     1321 ctgaaatcaa ttaaaacata ctaagataag attagagggt aaattcaggc tctttgtcaa
     1381 taaggactga tgagttttgt aaaatcaaat ctgggataga a
//
LOCUS       DAZUJR010000195         1394 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.200, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000195 DAZUJR010000000
VERSION     DAZUJR010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1394)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1394)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1394
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.200"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            33..1372
                     /locus_tag="ACG804_002950"
     CDS             join(33..474,474..1372)
                     /locus_tag="ACG804_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HFS4833806.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAENAYFKKVRNLDSRTRF
                     EQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYYWVKKLDKPDKYSKIKQEITAIVK
                     ESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMGLTCQIRIKRYKSYKGTVGKIAKN
                     VLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPILDLFNGEIISYSISTSPTYKLIEE
                     MLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLKENNIIQSMSRKGNCLDNSVIENF
                     FGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKRIKLKLNGLSPVEYRKQSIK"
BASE COUNT          579 a          181 c          244 g          390 t
ORIGIN      
        1 gactagaaat ctaattaaaa ggggtgcttt ttttgcggaa atatacattt gtttttaaga
       61 aaaaagtagt ttcagactat ttaaataacg aaggcggcta caaatatctt gcacataaat
      121 atcaaataaa tcgtacactg gttagacatt gggtaaggat ttataactat catggttggg
      181 aaggcttggt tggaggtggc aaaagctaca ctacaaaatt taaacttgat gttatagaat
      241 atatggaaac aaatggtctt tctatccaag aaactgctaa aaaatttaat atcggttcaa
      301 atagaactct aagtaaatgg atagagcaat atgaagaagg cggtgcttct tcacttgaga
      361 gccaaaaaag gggcagaaaa attagtatga attccaagct aaacattcct aaaaaactta
      421 aagatgagtc tcttgaagaa gaagttattc gtttaagagc agagaacgca tatttaaaaa
      481 agttagaaac cttgattcaa gaacaagatt tgagcaagaa gaaatcaagg ttaaaacaat
      541 ccttcagctc aaaaaagaat ttaaattgaa tctattactt tcaattgcac aattagcgaa
      601 gtcaacttat tattactggg taaaaaaatt agataagcca gataaatata gcaagataaa
      661 gcaagaaatt acagcgattg taaaagaatc aagaaactct tatggttatc gtagagtcac
      721 tttagcgtta aagatgaaag gatatacaat caatcataaa acagttagaa aattaatgtc
      781 ccaaatggga cttacctgtc aaatccgaat aaagcgatat aaatcttata aaggaacagt
      841 aggaaaaatt gccaagaatg tgttaaaacg aaatttttca gtagatacac ccaataaaaa
      901 atgggtgaca gacgtcactg aattcaagat aaaaggaaga aaaatctatc tatctcctat
      961 acttgattta tttaacggag aaataattag ttatagtata tcaactagtc caacatataa
     1021 actgattgaa gaaatgcttc aacaagcaat taaaaaaaag ggaactgagg gttcactgat
     1081 tctacattca gatcaaggat ggcagtatca gatgccacaa tatcaaaaaa aattaaaaga
     1141 gaataacatt attcaaagca tgtctagaaa aggaaattgc ttagataatt ctgtaataga
     1201 aaattttttt ggtgtgctta aatcagagtt tttttatcga gaaaaattcc gatcaattga
     1261 gatatttcaa agtaaattaa atgagtatat taggtggtat aataacaaaa ggataaaact
     1321 aaagttaaat ggactatctc cagtagaata tcggaaacag tccattaaat agttcaactt
     1381 ttggggttca gttc
//
LOCUS       DAZUJR010000196         1370 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.201, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000196 DAZUJR010000000
VERSION     DAZUJR010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1370)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1370)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1370
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.201"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            78..193
                     /gene="rrf"
                     /locus_tag="ACG804_002951"
     rRNA            78..193
                     /gene="rrf"
                     /locus_tag="ACG804_002951"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            203..276
                     /locus_tag="ACG804_002952"
     tRNA            203..276
                     /locus_tag="ACG804_002952"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:237..239,aa:Asn,seq:gtt)
     gene            316..405
                     /locus_tag="ACG804_002953"
     tRNA            316..405
                     /locus_tag="ACG804_002953"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:350..352,aa:Ser,seq:gga)
     gene            420..491
                     /locus_tag="ACG804_002954"
     tRNA            420..491
                     /locus_tag="ACG804_002954"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:453..455,aa:Glu,seq:ttc)
     gene            507..579
                     /locus_tag="ACG804_002955"
     tRNA            507..579
                     /locus_tag="ACG804_002955"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:540..542,aa:Val,seq:tac)
     gene            589..661
                     /locus_tag="ACG804_002956"
     tRNA            589..661
                     /locus_tag="ACG804_002956"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:622..624,aa:Asp,seq:gtc)
     gene            697..772
                     /locus_tag="ACG804_002957"
     tRNA            697..772
                     /locus_tag="ACG804_002957"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:730..732,aa:Phe,seq:gaa)
     gene            774..854
                     /locus_tag="ACG804_002958"
     tRNA            774..854
                     /locus_tag="ACG804_002958"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:808..810,aa:Tyr,seq:gta)
     gene            861..934
                     /locus_tag="ACG804_002959"
     tRNA            861..934
                     /locus_tag="ACG804_002959"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:893..895,aa:Trp,seq:cca)
     gene            937..1009
                     /locus_tag="ACG804_002960"
     tRNA            937..1009
                     /locus_tag="ACG804_002960"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:970..972,aa:His,seq:gtg)
     gene            1021..1092
                     /locus_tag="ACG804_002961"
     tRNA            1021..1092
                     /locus_tag="ACG804_002961"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1053..1055,aa:Gln,seq:ttg)
     gene            1138..1208
                     /locus_tag="ACG804_002962"
     tRNA            1138..1208
                     /locus_tag="ACG804_002962"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1170..1172,aa:Cys,seq:gca)
     gene            1229..1313
                     /locus_tag="ACG804_002963"
     tRNA            1229..1313
                     /locus_tag="ACG804_002963"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1263..1265,aa:Leu,seq:caa)
BASE COUNT          330 a          305 c          354 g          381 t
ORIGIN      
        1 actcggaaaa aaacttatgt gacttcaaat ccagttttga gtgaacaaaa tttactcaat
       61 aaaagataac accacagtgt ggtggcgata gcgagaagga tacacctgta accatgccga
      121 acacagaagt taagcttctt agcgccgatt gtagtgaggg gttgcccctt gtgagagtag
      181 gacgtcgcca cgctgatgtt attccggcat agctcagttg gtagtagcgc atgactgtta
      241 atcatgatgt cgtaggttcg agtcctactg ccggagttct cattttgaga aagagtattg
      301 agcttctttc actctggaga gttgtccgag aggccgaagg agcatgattg gaaatcatgt
      361 agatggtgcc aaactgtctc aagggttcga atcccttact ctccgtagca aatttacctg
      421 gcccgttggt caagcggtta agacaccgcc ctttcacggc ggtaacacgg gttcgaatcc
      481 cgtacgggtc attttaattg aatgttggag gtttagctca gctgggagag catctgcctt
      541 acaagcagag ggtcagcggt tcgatcccgt taacctccat aatgaactgg ttccgtggtg
      601 taggggttaa catgcctgcc tgtcacgcag gagatcgcgg gttcgattcc cgtcggaacc
      661 gtcgttcttg ttattcaatt aataatttta aaatatggcg cggtagctca gttggtagag
      721 caacggattg aagctccgtg tgtcggcagt tcgattctgt cccgcgccac catggaggag
      781 tagcgaagtg gctaaacgcg acggactgta aatccgttcc ttagggttca gtggttcgaa
      841 tccactctcc tccattttat aggggcatag tttaaaggta gaacagcggt ctccaaaacc
      901 gttagtgtgg gttcaattcc tgctgcccct gccatggcga atgtggcgaa gtggttaacg
      961 caccggattg tggctccggc attcgtgggt tcgattccca tcattcgccc tttttattct
     1021 tggggtatag ccaagcggta aggcaaggga ctttgactcc ctcatgcgtt ggttcgaatc
     1081 cagctacccc agtttctata atttattctt tattttatag attgataata gtataatggc
     1141 ggtatagcca agtggtaagg cagaggtctg caaaaccttc atcaccggtt caaatccggt
     1201 taccgcctta gtactaataa atcaacttgc cggcgtggcg gaattggcag acgcgctgga
     1261 ctcaaaatcc agtgcccgtt gagggcgtgc cggttcgacc ccggccgccg gtattgacta
     1321 agatgtcttc atcttagttt tttattgaga aattaaataa catcttttat
//
LOCUS       DAZUJR010000197         1364 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.202, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000197 DAZUJR010000000
VERSION     DAZUJR010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1364
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.202"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            82..>1364
                     /locus_tag="ACG804_002964"
     CDS             82..>1364
                     /locus_tag="ACG804_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HFS4833807.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQL"
BASE COUNT          465 a          262 c          257 g          380 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atcaatcaat taat
//
LOCUS       DAZUJR010000198         1295 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.203, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000198 DAZUJR010000000
VERSION     DAZUJR010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1295
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.203"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            35..532
                     /locus_tag="ACG804_002965"
     CDS             35..532
                     /locus_tag="ACG804_002965"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4833808.1"
                     /translation="MNNQITLAYLDYDDLDALQVVSVVSFYESFIDGADPLDMQGYLQ
                     TQLTTEILAVELAQSTSKFIGIKDHQILIGYMKVNDEKDAIEIQRLYLLKDYQNKGLG
                     QRLLDEANRYAKTKQKRYLRLTVYEKNHAGIRFYERHGFKKIGIKHFPLGKQDRICPI
                     LEKEI"
     gene            complement(569..1252)
                     /locus_tag="ACG804_002966"
     CDS             complement(569..1252)
                     /locus_tag="ACG804_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HFS4833809.1"
                     /translation="MTTEHFDLANPVTKVDDIPDYEMYSQTIDSLNKRFGNRVLKGIK
                     IGYIASEKDRIIDYLADKDYDLKLLSVHHNGQFDYLDDEVKDMDPAIVIPQYFAQLSE
                     ALVVIEADVFAHFDYGFRVFGLSVAEFKQYEAQFLPILDQVIKNKLAFELNAKSAYLY
                     DNLALYEYVIDLYLSRGGTLFSVGSDGHYLEHFRFHFDDLFALLKANGVTELAIYQKG
                     KRIMVPLPV"
BASE COUNT          447 a          220 c          228 g          400 t
ORIGIN      
        1 atttatagta tactatgtca aaaggaggag ttagatgaac aatcaaatca cactagcgta
       61 tttagattat gatgatctag atgctttaca agttgtaagt gttgtcagtt tttatgaatc
      121 gtttatcgat ggcgcagatc cacttgatat gcaaggatat ttacagacac aattgacaac
      181 tgaaatattg gcagtagaat tggcacagtc aaccagtaaa tttattggta ttaaggatca
      241 tcaaatactc attggttata tgaaagtcaa tgatgaaaaa gatgctatag agattcaacg
      301 gctctatctg ctcaaagatt atcaaaacaa agggttaggg caacggttac tcgatgaagc
      361 gaatcgttat gctaaaacga aacaaaaacg ttatttacgt ttgactgttt atgaaaaaaa
      421 tcatgcaggt attcgttttt atgaacgtca tggatttaaa aaaatcggga tcaaacattt
      481 tcctttagga aaacaagatc gtatttgtcc gattttagaa aaagaaatct aaaaaaacgt
      541 cctcactttt gatgctgagg acgttttttt agactggtaa tggaaccata attcgctttc
      601 ctttttgata aatcgctaat tccgtcacac catttgcttt taacagagca aaaagatcat
      661 cgaaatggaa acggaaatgt tcaaggtaat gcccatctga tccaacacta aacaaggtac
      721 caccacgtga aagatataaa tcgatgacat attcatataa cgctaaattg tcatacaagt
      781 aagcgctctt agcatttaat tcgaatgcca atttattttt gattacttga tctagaatcg
      841 gtaaaaactg cgcttcatat tgtttaaatt cagcaacgga tagaccaaat acccgaaaac
      901 catagtcaaa atgagcaaag acatctgctt ctataacaac tagtgcttct gaaagttgtg
      961 caaaatactg aggaatcaca atagcaggat ccatatcttt gacttcgtca tctaaataat
     1021 caaattgccc attatgatgc acactgagta attttaaatc gtaatcttta tcggctaaat
     1081 agtcgatgat ccgatccttt tcagaagcga tgtaaccgat tttgatgcct tttaaaacac
     1141 gattgccaaa acgcttattt aagctatcga ttgtttgact gtacatttca taatcgggga
     1201 tatcatcgac tttagtaaca ggattggcta agtcaaaatg ttcagttgtc acgacgtaac
     1261 catcgtagtt tgttaaatag tcctcatttc ttggg
//
LOCUS       DAZUJR010000199         1273 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.204, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000199 DAZUJR010000000
VERSION     DAZUJR010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1273
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.204"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..285)
                     /locus_tag="ACG804_002967"
     CDS             complement(<1..285)
                     /locus_tag="ACG804_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HFS4833810.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKDFF"
     gene            979..>1273
                     /locus_tag="ACG804_002968"
     CDS             979..>1273
                     /locus_tag="ACG804_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFS4833811.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFNKTD"
BASE COUNT          479 a          197 c          152 g          445 t
ORIGIN      
        1 aaaaaaatct ttatcaatat tatttgctct aaatggacca aataagtaat atctggtttt
       61 aaacatgtat agaagaaaca tctcattaaa atcaccagta aagaaatgga aatctttagt
      121 ttttttaata ttatcagtta gtaacttttt ataatcataa aaaaaataag tagttctatc
      181 tgagcgatac tcttttataa tactgaattc ggaattaaaa accacgatag gtaactttaa
      241 acaaacatga agagacttta ataagacttc tttatctgaa aacacttttg tttctctctt
      301 tcctttctac atcattaaat agtattttat acgttatcta aaatactatt cctctgtcaa
      361 aataagctaa cttacttcat tataaaatat ccacttatcg ctttcatgta tattccaccg
      421 taaaaagtac attttatcac cgagaactca tcatttttca tcatgatgaa tactatttac
      481 atatatctag ttcaaagaca ataattatta tgatccgtta ttatctaagc actatacaga
      541 taataggaat ttttcgtttc taaatactcc aatttgggaa tccaataaaa attttcgttc
      601 aaatacgtgt ctattcgaac tcttttctag ttgttaatta tgaaggggga agaaataaaa
      661 aatacaatct atacacgaat aagaatatta tccaaaagga ggttttagaa aagatttatt
      721 atacgtaaaa agctcaagac attttcttag ccataaggac atgtttgata tttaagaaga
      781 tatatgaatt ttcttttcta agtataaaga taactatcca ttatcaacta aaaaaacatt
      841 tttgaaaata aacatcagca gtcctatcaa tgcatgtgag cttatagaag ttattcgcag
      901 cgcagcataa ttgcattagc ttcttttcgt gttttttgcc tcttttccct ttaaatctta
      961 atggaggagg tgtgcaatat gtcagataac gacgaacgcg taaatgccca gttgattcga
     1021 ttctttgaaa aggtcatttt gaacaccgct aatacttatt ataaaaaaca agaagaaatt
     1081 caaaaacatg aacaacttga tcaactccca ccatatttgt ttactaaaga tactataaaa
     1141 tttaaacaac cgattaatgt tttaaatgtg actctccttg ttgaagatat aaaattagca
     1201 aaaatccttc ctttgttgaa agaacctgaa caaatttttc ttatcgaaaa atttatcttt
     1261 aataaaactg ata
//
LOCUS       DAZUJR010000200         1195 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.205, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000200 DAZUJR010000000
VERSION     DAZUJR010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1195
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.205"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1076
                     /locus_tag="ACG804_002969"
     CDS             <1..1076
                     /locus_tag="ACG804_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFS4833812.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          211 g          332 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tcttg
//
LOCUS       DAZUJR010000201         1088 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.207, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000201 DAZUJR010000000
VERSION     DAZUJR010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1088
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.207"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>1088
                     /locus_tag="ACG804_002970"
     rRNA            <1..>1088
                     /locus_tag="ACG804_002970"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          287 a          250 c          332 g          219 t
ORIGIN      
        1 gaaataatag taccgaagtt cctgatgtca cactgccgag aaaagcttct agtgagaaaa
       61 cagcggcccg taccgcaaac cgacacaggt agtcgaggag agaatcctaa ggtgagcgag
      121 agaactctcg ttaaggaact cggcaaaatg accccgtaac ttcgggagaa ggggtgctga
      181 tcatacgatc agccgcagtg aataggccca agcgactgtt tatcaaaaac acaggtctct
      241 gcaaaatcgt aagatgaagt ataggggctg acgcctgccc ggtgctggaa ggttaagagg
      301 agtgcttagc gcaagcgaag gtacgaattg aagccccagt aaacggcggc cgtaactata
      361 acggtcctaa ggtagcgaaa ttccttgtcg ggtaagttcc gacccgcacg aaaggcgtaa
      421 cgatttgggc actgtctcaa cgagagactc ggtgaaattt tagtacctgt gaagatgcag
      481 gttacccgcg acaggacgga aagaccccat ggagctttac tgtagtttga tattgagtgt
      541 ctgtaccgca tgtacaggat aggtaggagc cgtagaaatc ggaacgctag tttcgatgga
      601 ggcgctggtg ggatactacc cctgcgttat ggccactcta acccgcacca ctaatcgtgg
      661 tgggagacag tgtcagatgg gcagtttgac tggggcggtc gcctcctaaa aggtaacgga
      721 ggcgcccaaa ggttccctca gaatggttgg aaatcattcg aagagtgtaa aggcagaagg
      781 gagcttgact gcgagaccaa caagtcgagc agggacgaaa gtcgggctta gtgatccggt
      841 ggttccgcat ggaagggcca tcgctcaacg gataaaagct accctgggga taacaggctt
      901 atctccccca agagtccaca tcgacgggga ggtttggcac ctcgatgtcg gctcgtcgca
      961 tcctggggct gtagtcggtc ccaagggttg ggctgttcgc ccattaaagc ggcacgcgag
     1021 ctgggttcag aacgtcgtga gacagttcgg tccctatccg tcgcgggcgt tggaaatttg
     1081 agaggagc
//
LOCUS       DAZUJR010000202         1059 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.208, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000202 DAZUJR010000000
VERSION     DAZUJR010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1059
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.208"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(37..993)
                     /locus_tag="ACG804_002971"
     CDS             complement(37..993)
                     /locus_tag="ACG804_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833813.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          344 a          176 c          160 g          379 t
ORIGIN      
        1 ttagaaaaag cagtcggact ttctaaaaga agttcactat tcgatcctgt cgatgatttc
       61 ttcaggaaaa tcgtctattt gcttgtcaat tttgctgtct ttgtatttct cttcttggat
      121 agtcaacaaa atctttgtaa gattccccca gtctactgct cttggcggat cgagccaaac
      181 cactacttga gatgcacttt cttcatatag attattccta ttcgtgatta taacatccgg
      241 gaactcaggc tttcctgcct ctatcacttc cgtgttcaga ttaatgtaca agcttaaatt
      301 tttcttgata aattgattat aggcagcacc ataagaaaaa tcgatgatga tctttactgg
      361 ttcagaaatc agttgaatgg gtatgtgatt gatcaataat aataaataac tgaaaaaaag
      421 aaaaaattta tcttgaagca actctttgcg ttttgacgtt agatcattta tatactctat
      481 caaatagcaa taaaatgctg gatagttttc tctaaaaaaa gaaacatcaa gtggaaattc
      541 atcagcttta ttaatagtgt aatgcaaaag tttaaaatgt attttggtta actctcttcg
      601 gatcaattgg ctcgtctctt ctcgcaacag attaaactga ttttcaaaac tttcaatgaa
      661 tcgttcattc aaccattcga ttgtttcatc ttcatttttt ctcaagtatt tttgatccaa
      721 tttatcatga agataaagcc aagagagtgt cttattgata aaaataacgg atttttctcc
      781 taatactcct tttaagtggt aaaatcctat atccgaaaaa aatagcgact gattgctagc
      841 aatatctaaa gaatcagctt gttcagccaa caggttgatt gctaaaaagt ggaataattt
      901 ctttttttca taagcagaca gaggataata ctgttttaaa tcttttaaca ttttttctgt
      961 ttttataatt ataggtagcg tatacaattc cacaaaactt atctctgttg agttaaaaag
     1021 attatataaa aaaagccgaa tgtttttagg attccctgt
//
LOCUS       DAZUJR010000203         1055 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.209, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000203 DAZUJR010000000
VERSION     DAZUJR010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1055
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.209"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            15..>1055
                     /locus_tag="ACG804_002972"
     CDS             15..>1055
                     /locus_tag="ACG804_002972"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833814.1"
                     /translation="MDLPFSLKLNFGYKSEEQEYELLFFQDEASLLEYTPVKVKEFSN
                     LSFTFNSIDKHAKLYIPELDDYLIENQVKEENGDICYIPSDDNIIIYNRDQGKTVPLI
                     PGYYTLYVKIGETIFYSRFEIILKDLGTPEWEKMKIEIEKMVGGLARTFIPKKTSRRE
                     ITTSNYLMNDQLFQRILEFENNIPQAIVSLESLKKEAKYRIDKRYNWKPIGSKNLVDQ
                     KTISQLQIHPEKRGLLYTPSRIIKYDIIENQWIKFILSYFKNFSLLADRYLEKILQGI
                     IEEKKREDKFTSAYSQSVQNYNTNSYNRKIENLKNNQQKIKHFYAYILEFLDTPVMKN
                     ISSRRPINVPKSL"
BASE COUNT          434 a          143 c          153 g          325 t
ORIGIN      
        1 ggagttgaat ttacatggat ttacccttta gtctgaaatt aaactttggt tataaaagtg
       61 aagaacaaga atatgaactt ttattttttc aagatgaggc atcgttatta gagtatacac
      121 cggttaaggt aaaagaattt tctaatctaa gctttacatt taacagtata gacaaacacg
      181 caaaactata tataccagaa ttagatgatt atttgattga aaatcaagta aaagaggaaa
      241 atggagatat ttgctatatt ccaagtgatg ataatataat catttataat agggatcaag
      301 gtaaaacagt acctcttatt ccaggttatt acactcttta cgttaaaata ggtgaaacta
      361 tcttttattc tcgatttgaa ataatactta aagatttagg tacaccagaa tgggaaaaaa
      421 tgaaaatcga aattgaaaaa atggttggcg gtcttgctag aacttttatt cctaaaaaaa
      481 cttctcgtcg tgaaattact acttcaaatt atctaatgaa cgatcaactt tttcaacgaa
      541 tattagagtt tgagaacaat atacctcaag caatagtttc tcttgaaagt ttaaaaaaag
      601 aagcaaaata tagaattgac aaacgatata actggaaacc aattggaagc aaaaatttag
      661 tggatcaaaa aactatttca cagttgcaaa tccatccaga aaaacgtggg ctactatata
      721 cacctagccg cataataaaa tatgatatta ttgaaaatca atggatcaaa tttatcttat
      781 cttattttaa aaatttttca cttctagctg atagatattt agagaaaatc ctacaaggta
      841 ttattgaaga gaaaaaaaga gaagataagt ttactagcgc gtattctcaa agtgtacaaa
      901 actacaatac aaatagctat aatagaaaga ttgaaaattt gaaaaacaat cagcaaaaga
      961 taaaacattt ttatgcttat atccttgaat ttttagacac accagtaatg aaaaacattt
     1021 catcaagaag acctataaat gttccaaaat cactt
//
LOCUS       DAZUJR010000204         1043 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.210, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000204 DAZUJR010000000
VERSION     DAZUJR010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1043)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1043)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1043
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.210"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            4..978
                     /gene="bsh"
                     /locus_tag="ACG804_002973"
     CDS             4..978
                     /gene="bsh"
                     /locus_tag="ACG804_002973"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HFS4833815.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          374 a          132 c          182 g          355 t
ORIGIN      
        1 actatgtgta cgtctattac ttatgtaaca agtgatcatt attttggaag gaattttgat
       61 tatgaaatat cttacaatga agtagttact gttactccaa gaaattataa gttgaatttt
      121 cgaaaggtaa atgatttgga tactcattat gcaatgattg gtattgccgc tggtatagct
      181 gactaccctc tttattacga tgcgacaaat gaaaaaggat tgagtatggc tgggctaaat
      241 ttttctgggt atgctgatta taaagaaata caagaaggga aagacaatgt atctcctttt
      301 gaatttattc cttggatttt aggacaatgc tcaacagtag gagaagctaa aaaattgtta
      361 aaaaatatca atttagcaaa tataaattat agtgacgaac ttcctttatc ccctttacat
      421 tggctattag ctgataaaga aaaatcaatt gtcattgaaa gtatgaaaga tggacttcat
      481 atatatgata accctgtggg cgttcttacc aataatcctt catttgacta tcaattattt
      541 aatttaaaca attatcgtgt cttatcgagt gaaactccta aaaataattt ttcaaatcaa
      601 ataagtttga atgcctatag ccgcggtatg ggagggatag gcttgcctgg agatttatcc
      661 tcagtatctc gttttgttaa agcgactttt acgaagctga attctgtatc tggagattca
      721 gagtcagaaa gtattagtca atttttccat atcttaggtt cagtagaaca acaaaaaggt
      781 ttgtgtgatg taggtgatgg aaaatatgaa tatacaattt attcttcttg ttgcaatgtt
      841 gacaaaggaa tctattatta tcgaacatat gaagacagtc aaattactgc aattgatatg
      901 aataaagaag acttagatag tcataagtta attagttatc caattataga aaaacaacaa
      961 attaaatata taaattagtt aatgtgttgt gattgattat ttaatataga tataatacaa
     1021 aaaggcaaag atattttcaa aac
//
LOCUS       DAZUJR010000205         1018 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.211, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000205 DAZUJR010000000
VERSION     DAZUJR010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1018)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1018)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1018
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.211"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>1018
                     /locus_tag="ACG804_002974"
     CDS             <1..>1018
                     /locus_tag="ACG804_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833816.1"
                     /translation="VKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAFHINRALSLESIF
                     SSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLYIVTLITLFICHY
                     VMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPLILLGFIKLYDSK
                     KESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIFLIIKLIKAAIVT
                     LLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDSELLSFGIGLTLL
                     ICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLNIIQAPWRFMIFS
                     TLFIS"
BASE COUNT          322 a          142 c          138 g          416 t
ORIGIN      
        1 ctgtaaaaat atttatagtt tatgcatttg ttagtttatt atatttattt ccagcattta
       61 aaaacatgga aatatttggc ttttatgata cggcatttca cattaatcgt gcgttaagtt
      121 tagaatctat ttttagctcc cctattaatt ttgaaacgtt tagatcatat ggcatgcaag
      181 taaataattt ttacccatgg ttaactctat atcctttatt tttattgatc aagtttacta
      241 atttagcaat aggctataac ctttttcttt atattgttac gctcattact ctatttatat
      301 gtcattatgt aatgtatgaa attaccaaaa aacatgttac tagctccttt ttcgctatta
      361 tatatacaac atcttctttt aggagtgtag aaatatttct tcgaggggca atgggggaat
      421 tactcgcaat gtcaatactt cctcttattt tactcgggtt tataaagctt tacgactcaa
      481 aaaaagaatc ttgggttatg ttggcgatta gcatgacttt attaatttac actcatgttc
      541 tttctgtagc tatgactatg gtaatgatta taattgcttt aattattcaa ttttatcgga
      601 aaaagaaaat agaaatcttc ttaattatta aattaataaa agctgctata gttactttac
      661 ttctttcact agcgtttata ggtcctatga ttgagcagac attgtatcaa gatctgaata
      721 gaccttatgt ggatatatta caaaaaagag caatttatct gggtaaagag tttttgattg
      781 gaagtataga ttcagaatta ctatcatttg gtattggctt aactttgctt atttgtttaa
      841 ttatactaac atttaacttt aaaaaattag gaatcttatc taaaatcact tatataatgg
      901 gtataatatc tattctactt tgtacaaaaa tatttccatg gtttgcctta caaaatactc
      961 ctttaaatat tattcaagct ccttggcgtt ttatgatatt ttcaacattg ttcatatc
//
LOCUS       DAZUJR010000206         1001 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.212, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000206 DAZUJR010000000
VERSION     DAZUJR010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1001
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.212"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            370..1001
                     /locus_tag="ACG804_002975"
                     /pseudo
     CDS             370..1001
                     /locus_tag="ACG804_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          342 a          181 c          184 g          294 t
ORIGIN      
        1 gtttcaaagt tagtagagaa aatgtagtta tatatttaaa tttttaccag aaagaaatga
       61 acaccttcaa ttatctaaat ctcgaaaatg gttagatgta atcatcagga aaaacaatct
      121 taaacgaatt actattcatg gtcttagaca cacacatgct agcttgcttt tagcaagcta
      181 gtgcaaatat taaagatgtg caagagcgtt taggccactc ttctattcaa atcattatgg
      241 atctatatat tcatattaca gacaaaagaa aagaagaaac cgtagcgcaa ttcgcaaaat
      301 ataggctcta taatttatgg gactgatgaa tcaaaattga ttcttcagtc ccattgttat
      361 tttaggtata tgattcgtac attgaaagag ttgaaaaact atcttccgaa gccgtcaaaa
      421 aggaccctgc caaaagtatt gatggtggat gaatttcgtt cgcacgcttc aattgtggat
      481 aaaatgagct ttatttgtgc ggatggcgag actggaaaac tcattgatat tttgcctaca
      541 cgaaaattgt ctcgattaac acactatttt agtcgctgtg caaatcctga agcggtggaa
      601 tatttagtga cagatatgaa cgccgcctac ttccaactga caaaacgtgt cttaccaaat
      661 gcgaaagtcg tcattgattg ttttcatatc atcaaacatt tgaatcaggc gttcaatgat
      721 tttcgtgtac aagaaatgaa aagattacac cagttagggc aacgacggga agccgagaaa
      781 gtgaaaaaga actggcgctt tcttctaaaa aaccgtcaaa aaatcaatca ctatgattac
      841 aaaacatggc gcagttttcg tgcacctaaa tacccgctac tcactgaagc aatgatgatt
      901 gatcgattgc tggcattttc aacgccttta aaggacgcct atactttttt ccatgagctg
      961 accgaagcct ttagagacaa ggaatcagac ttatttttta c
//
LOCUS       DAZUJR010000207          959 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.213, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000207 DAZUJR010000000
VERSION     DAZUJR010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..959
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.213"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(107..511)
                     /locus_tag="ACG804_002976"
                     /pseudo
     CDS             complement(107..511)
                     /locus_tag="ACG804_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
     gene            complement(570..>959)
                     /locus_tag="ACG804_002977"
     CDS             complement(570..>959)
                     /locus_tag="ACG804_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFS4833817.1"
                     /translation="KDRKEICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSL
                     IENQDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFD
                     TYNQKFLNRSHKGFQQVTDTLVSMFTE"
BASE COUNT          287 a          170 c          159 g          343 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctgagacacg acctaaagat cgtgtctaat
       61 tatgactgta tcagaaaata tgataccaaa cggatctatt cattaattaa ttgacatagt
      121 ttatctgttg ctcttttatg actggataac tgaccaattc atgacgatcc aagtcttctt
      181 tattcatatt tacagcagta atttgactgt cttcatacgt acgataataa taaatccctt
      241 tatcaacgtt acagcaagaa gaataaatcg tatattcgta ttttccttct ccagtatcgc
      301 atactccttt ttgttgctcg actgagccta gtatatgaaa aaattgactg atactttcag
      361 attctgaatc acctgatgca gcattcattt tagtaaatgt ggcttttaca aatcgagaaa
      421 cagaagagag atctccaggt aagcccaatc ctcccatccc acgactataa acattcaagc
      481 tgatctggtt tgaaaaatga ttttctggtg ttccattggg agcgtcaata attttgtgta
      541 aataaattgt cctcctgcaa aataattagt tactcagtaa acattgaaac taatgtatcg
      601 gttacctgtt gaaaaccttt atggcttctg tttagaaatt tttgattgta tgtatcaaaa
      661 atgctgacta gaaagcgttc tagtgattct tcattttgaa actgctcttt tctacggctg
      721 tatcttttaa tttgcttatt gaaagactcg attagattgg ttgagtaaat ggttctacga
      781 atgctaggtg gaaaatcata aaaagttaat aagtcttggt tttctatgag tgactgcgtc
      841 actttaggat agtttttctt ccatttctca atcatgccgg ataagaaggt attcgcttct
      901 tcttttgagt tagcttgata aacagcctta aagtcatcac agatttcttt tcggtcttt
//
LOCUS       DAZUJR010000208          946 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.214, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000208 DAZUJR010000000
VERSION     DAZUJR010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 946)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 946)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..946
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.214"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            67..759
                     /locus_tag="ACG804_002978"
     CDS             67..759
                     /locus_tag="ACG804_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFS4833818.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT          415 a          145 c          159 g          227 t
ORIGIN      
        1 cttgacattg tgtttgagat cacttacttt tagcatgtaa aagtattgga ttaaggagct
       61 atgcaaatga aaaagaaatt tattactggt gggattgtcg ttgcatttct atgtctaatt
      121 ggctacacag gcacgcggta cgcaaatgaa attattttgt ggggtggaga gacagatatt
      181 gatacaatca atgagaatct gacacagctt gatcatacat tgacagataa agagcaagcg
      241 attacagatc ttaccgctcg actagcacaa aaagaacaga cattgcaaga ttcaaaggca
      301 gatgtccaag aataccaaac aaaagtaaat gaattagaaa accaaaaaaa tcaatcggca
      361 gcagaaaaac aaaacttaga aagtcaatta gtcagcaagg atgcacaact acaaagcaaa
      421 caaaatgaaa tcaatgtcaa actagatgag atcaaccaaa aaaatgatga aatcaatcat
      481 ctgaatgcag attggacagc aagactacaa gaagcacaag caaaactttc agaattacaa
      541 aatactgtaa atggtttgaa tcaacaaatc gcaacactga cacaagaaaa aacaaatgta
      601 gaaactcagt taacagatac acaaaagaaa ttagacgaag caactgctga aaactcaagc
      661 ttgaaacaat atattcaaaa gttagaaaaa gcaaaagatg aagtggaaga tacagctgat
      721 aaatctcagc aaattgttga agaacatttg cgtaaataat ctttcttaac aagtaaacct
      781 aaattagtaa agaagcaaca gtaatctata ctaagtagtt cagttttgga gtacaaaatg
      841 acaaaatgta cttcaaaatg gactactttt ttcattttaa cttacatacc aaattacata
      901 caaaatgatt tataaaatgc aattgaaaat gataattgaa tgaaaa
//
LOCUS       DAZUJR010000209          943 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.215, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000209 DAZUJR010000000
VERSION     DAZUJR010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.215"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>943
                     /locus_tag="ACG804_002979"
     rRNA            <1..>943
                     /locus_tag="ACG804_002979"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          293 a          187 c          274 g          189 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga attgagaatg atggaggtag agcactgttt ggactagggg cccatctcgg
      781 gttaccgaat tcagataaac tccgaatgcc attcattcat atccgggagt cagactgtga
      841 gtgataagat ccatagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
      901 tatgttaagt ggaaaaggat gtggggttgc acagacaact agg
//
LOCUS       DAZUJR010000210          905 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.216, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000210 DAZUJR010000000
VERSION     DAZUJR010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..905
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.216"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            1..905
                     /locus_tag="ACG804_002980"
                     /pseudo
     CDS             1..905
                     /locus_tag="ACG804_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
BASE COUNT          330 a          157 c          172 g          246 t
ORIGIN      
        1 atcttacgcc tgaacaaaaa gaattgttag aactacgtaa aagaaaccag caattagaaa
       61 tggaaaatga tattttaaag caagcagcgc tgatattcgg acgaagagac aagtaatcga
      121 tgcgaataag catctttacc ctatatcagc gatgtgcaga atattaggtc tatcacgtca
      181 gtcctattat tatcaatcaa aaccaaagaa agacgaatca gaacttgaag aagtagtcgc
      241 tgaagaattt atccgcagcc gaaaggccta cggctcaaga aaaataaaaa aagccttatc
      301 aaaacgaggc attcagatca gccgacgaaa aattagtaga atcatgaaaa atagaggatt
      361 aaaatcgagc tatactgttg cttattttaa agtacatcat tctacttgca atgaagccaa
      421 aacgacaaac gtattgaatc gtaaattctt aagagacaac ccattagaag cgatcgtaac
      481 agacttgact tatgtacgag tcgggaaaaa atggaattat gtctgtttca ttttggatct
      541 gttcaatcga gaaattctcg gctattcttg tggagaacat aaagatgccg ttctagtaaa
      601 aaaagcattt agccgtatca aacaacctct gacagaggtt gagatttttc atactgatcg
      661 tggaaaagag tttgataacc aagctattga tgaattatta acaacttttg acatcaatcg
      721 atcattgagt cataaaggct gtccttttga taatgccgta gctgaatcaa cttataagtc
      781 gttgaaagta gaatttgtct atcaatacac atttgaaacc ttacaacaat tggatttgga
      841 gttatttgac tatgtcaatt ggtggaacca ccttcggttg cacggtacac ttggctacga
      901 gacac
//
LOCUS       DAZUJR010000211          885 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.217, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000211 DAZUJR010000000
VERSION     DAZUJR010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..885
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.217"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            136..309
                     /locus_tag="ACG804_002981"
     CDS             136..309
                     /locus_tag="ACG804_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833819.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
BASE COUNT          296 a          144 c          107 g          338 t
ORIGIN      
        1 ttttcggaga attaaaaaat acaataaata actttagtta ctttaatgcg ttcttacttt
       61 atttttatat tatcattttt cttattcact tctttggttt atactattct tataaataaa
      121 aacgaggtat gtcctatgat gaaaagattg tactattcat tgatcataac gattggctat
      181 ttgattgtat caaatctagg aaatatggta tttggtatca gtaaagaatt cagttggact
      241 actacattat gggaatctct attctttttc atcttcgtat ttttgttaca aaattatcga
      301 aaaaaataaa catgtgccat ctatctgttg gcacatgttt taggatttat ggtacttttt
      361 attcggcaat ccattttatt tttctacttc ttcttaatac ctctaacact tttgatttat
      421 aaactaatcc aatgcatcta cttgcgctta ttaagctatt tcagctagat agtaccaccc
      481 catgcgtcaa tgcttgattt tccttttgta taacattgta taagcaataa aggacaaata
      541 agtggtgatt acaccaaacc attgaataag aaaaattctg atacgtaaat aaacatgaac
      601 ttgaaaaaat taatgaatcg gttagctact acgtagttgt cttttttctc atacagttct
      661 gttaacttac acttctcttc gctagataat aaaaaatcct ccaactgtat tgtccaatat
      721 aatcccaggc atctaaacta gcattataga agagacacac atagaatcta aaataactgg
      781 ttttaaatgt ttcttacaat caaaaaaagc tgttaaatgc actccacacc ttcatactct
      841 atcatttttt ataaacgata tatttttatt gtttttcgat aaaaa
//
LOCUS       DAZUJR010000212          851 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.219, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000212 DAZUJR010000000
VERSION     DAZUJR010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..851
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.219"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            164..796
                     /locus_tag="ACG804_002982"
     CDS             164..796
                     /locus_tag="ACG804_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFS4833820.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
BASE COUNT          309 a          121 c          134 g          287 t
ORIGIN      
        1 agaattacgc ctaatttgtg tctctcaggg caattctaag aacgtttcaa gagatagcga
       61 cactatcgtt atcgaaaaag gcgaaaacct atctcatttt ctgctaatgt aagttggttt
      121 agcttttgtt aatatgactt tatgaaaatg gaggtaatta aatatgattt ttcctaaagt
      181 taatgaagca agcttgaata aaggatcctt ttttcatatc tatgaaaacg aagattttga
      241 actgtataat atcctttcac aaaaagaggt catcgaaaac caaataatct gccatccaat
      301 tatttacaaa tctattttca agtatgcatt ttttgcttcc aatgattttc aaagaatgga
      361 gattaccgac tgtatattcg aaaactgtga tttttcaggc tgtatattga caaaaagcat
      421 gttgcatcgc gtgaaatttg tcaattgtaa attaacaggt actaaattga tggaaagtta
      481 tattgggaac acgttattcg agaattgtaa aatggactat gtaaatttat ctggttcaaa
      541 cataaaagaa agtacctttg agcactctgt cttatcaagc gcagattttg tagactgttc
      601 cctcactaaa ataatgtttt ctactaatga tttagaaaat gctagctttt ttgatactga
      661 tttaaaaaat atcgatttaa gtagcaactc ctttgaaatg attgaagtac gctcggaaca
      721 tctaaaaaat tgtacgctta atcagttgca agcacttggt tttgctagaa aatttttaca
      781 aataaaagta gtataatcaa aatgaatata taagataaat ttttagcaat acaaatatcc
      841 ataaaaaaac a
//
LOCUS       DAZUJR010000213          848 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.220, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000213 DAZUJR010000000
VERSION     DAZUJR010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..848
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.220"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>848
                     /locus_tag="ACG804_002983"
     CDS             <1..>848
                     /locus_tag="ACG804_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition family protein"
                     /protein_id="HFS4833821.1"
                     /translation="INDEYNLAPNQGDSRLAIPNKIILHETGIDAPARNVAANMKNNY
                     NGSNSYTTDVIGDGGIVYRVGEQGYVSWGAGNANPYAPVQIELQRTYDKALFEKNYRA
                     YIEYTRDSAKKYGIPLTLDQGTSLFTKGIISHLWVTNYVWGNHTDPYGYLSQMGVSKE
                     KLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNHAHIDQFGEIENANLHV
                     AGWHIANYKYEYIFIMDYNTGKELARVRADGIYRPDVNQAYNTSGNVGYHVSFNMRNF
                     PSKKVYV"
BASE COUNT          289 a          143 c          176 g          240 t
ORIGIN      
        1 attaatgacg agtataattt agcgccgaat caaggagact ccagattagc aattcctaac
       61 aaaattattt tgcacgaaac tggaatagat gcaccagcaa gaaacgtagc cgccaacatg
      121 aaaaataatt ataacggaag caattcttat actacagatg ttattggtga cggtgggatt
      181 gtttaccgtg tgggtgagca aggatatgtt tcgtggggag ctggtaacgc taatccttat
      241 gcgcctgtac agattgaatt acagcgcaca tatgataaag cattgtttga aaaaaactat
      301 cgagcttata ttgaatatac aagagatagt gcaaaaaaat atggaattcc attgactctt
      361 gatcaaggaa cttctttatt tacaaaagga atcatttctc atttgtgggt gacaaattat
      421 gtttggggga accacacaga tccatatggt tacttatcgc aaatgggagt tagcaaagaa
      481 aagcttgctt atgatttagc tcatggattt accgatgaaa atccaacaac ttctgaaaac
      541 aagcctgtca ttgatccaac acgagctggt gcagctaatc ctacgctgac agatggaaca
      601 aatcacgccc acattgatca gtttggggaa atcgaaaacg caaacttgca tgtggctgga
      661 tggcacattg ctaactataa atacgagtat attttcatta tggactacaa tactgggaaa
      721 gaattagctc gagtaagagc tgatggaatt tatagaccag atgtaaacca agcttataat
      781 acttctggaa atgttggtta tcatgtatct ttcaatatgc gtaattttcc tagtaagaaa
      841 gtctatgt
//
LOCUS       DAZUJR010000214          771 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.221, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000214 DAZUJR010000000
VERSION     DAZUJR010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..771
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.221"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            116..482
                     /gene="ssrA"
                     /locus_tag="ACG804_002984"
     tmRNA           116..482
                     /gene="ssrA"
                     /locus_tag="ACG804_002984"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
BASE COUNT          251 a          126 c          150 g          244 t
ORIGIN      
        1 aaaggggcag ttattatata aataatggga tatgattcgc ttttttattg aatttatccc
       61 aatatatgct atactaattt tgtatgaaaa atacacgtaa cccttgttag ctaacgggga
      121 cgttacggat tcgacaggca cagtcgagct tgaattgcgt ttcgtaggtt acgtctacgt
      181 aaaaacgtta cagttaaata taactgctaa aaacgaaaac aactcttacg ctttagctgc
      241 ctaaaaacag ttagcgtaga tcctctcggc atcgcccatg tgctcgagta agggtcctaa
      301 ctttagtggg atacgtttca actttccgtc tgtaagttga aaaagagaac atcagactag
      361 cgatacagaa tgcctgtcac tcggcaagct gtaaagtgaa tccttaaatg agttgactat
      421 gaacgtagat ttttaagtgg cgatgtgttt ggacgcgggt tcgactcccg ccgtctccat
      481 atatgtatgg ttgagacaga taaacatgta tgaaaaacgt tgttaaatca acgttttttt
      541 attttggtca aggagagaaa agtagagaaa tacaaaattt tttgcattga ttttgcattc
      601 aaaaaaacat tcaaacattt agaaatcccc aatacgtatt caggaaaatc tattttaagg
      661 tttacaaaaa gaacttttgt tcgtacactc tttttgaggt gaacttttat gctgatggaa
      721 ggaaaaacac aattatggtt taagcatgtt ccttcaaata agttttttta a
//
LOCUS       DAZUJR010000215          706 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.222, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000215 DAZUJR010000000
VERSION     DAZUJR010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 706)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 706)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..706
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.222"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>706
                     /locus_tag="ACG804_002985"
     CDS             <1..>706
                     /locus_tag="ACG804_002985"
                     /inference="COORDINATES: protein motif:HMM:NF016309.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="nuclease domain-containing protein"
                     /protein_id="HFS4833822.1"
                     /translation="SRNNRNTLNFSNRYQYYWKSTDVLYEIWCFIKIIRSLSLQGYTP
                     ISGWIFENDILSQELPFLHEDTTVVLSKNDIRINLVYNNSMEKEYFSNTLDIPVKTSS
                     KRNKPDIRLDIILQDKYYIGSLIFEVKYKKLDNILDNDKGRQRQQLMAYKQNTMSSIL
                     AFPEILTRSLQAVSAVFALYPSNEGRKKTAPKYYEKEGIFFHLLNPSSDEKELSVKIQ
                     TSIEERISLFNQQSRN"
BASE COUNT          279 a          104 c           93 g          230 t
ORIGIN      
        1 aaagtagaaa caatcgtaat actttaaatt tttcaaatag atatcagtat tattggaaaa
       61 gtacagatgt actctatgaa atttggtgct ttataaaaat tattagatct ctatccctgc
      121 aaggctacac tccaatttct ggatggattt ttgagaatga tattctttca caagaattgc
      181 cgtttttaca tgaagacact accgtagtat tgagtaaaaa tgatatacgt attaatcttg
      241 tatataataa ttccatggaa aaagaatatt tctccaatac actagatatc ccagtaaaaa
      301 cctcttcaaa acgaaataaa cctgatatta gattagacat tatccttcaa gataaatact
      361 atatcggaag cttaatattt gaagtaaaat ataaaaaact agacaatata cttgataatg
      421 ataaaggtag gcaacgtcaa caattaatgg cttataaaca aaatactatg tcaagtattc
      481 tagcatttcc tgaaattctt acacgttctt tgcaagctgt ctctgctgtc tttgctttat
      541 atccttccaa tgaaggaaga aaaaaaactg cacctaaata ttatgaaaaa gaaggtattt
      601 tttttcactt attaaatcct tcatcagatg aaaaagagct ttcagtaaaa attcaaacaa
      661 gtattgaaga aagaatttca ttatttaatc aacaaagtag aaatta
//
LOCUS       DAZUJR010000216          702 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.223, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000216 DAZUJR010000000
VERSION     DAZUJR010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..702
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.223"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..408
                     /locus_tag="ACG804_002986"
     CDS             <1..408
                     /locus_tag="ACG804_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HFS4833823.1"
                     /translation="FVEFGSDAINPYKIIKYSDIDLIETDLGNKTLGQTIHNKRCYVI
                     LINQNLSPSMKRFVLWHEIAHVRLHKGICTAAFRANNLSCMIYGIEAEANMFAIEMLT
                     RTIDEQDLSDMSQFQIIEYLGLPHNLEHLVLQH"
     gene            499..>702
                     /locus_tag="ACG804_002987"
     CDS             499..>702
                     /locus_tag="ACG804_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833824.1"
                     /translation="MLLLIGLILLIIGITKLSKANTIKKEAYELEQKNDEKLNKLHDR
                     ERFILSKEETLSDLNKQITMLKND"
BASE COUNT          290 a           86 c          103 g          223 t
ORIGIN      
        1 tttgtagagt ttggatctga tgcgattaat ccatataaaa taatcaaata ttctgatata
       61 gatttaattg aaactgattt agggaataaa acattaggac aaacgataca caataaaaga
      121 tgttatgtga tattaattaa tcaaaaccta tcaccttcta tgaaaagatt tgtattatgg
      181 catgaaatag cccacgttag actccataaa ggtatttgca cagcagcttt tagagcaaac
      241 aaccttagtt gtatgattta tggtatagaa gctgaagcta atatgtttgc aattgaaatg
      301 ttaactagaa caatagatga acaagattta tctgatatga gtcagttcca aattattgaa
      361 tatttagggc ttcctcataa tcttgaacat ttagtattac aacattaaaa ataaaaaagc
      421 ccatgctttc acatggactc tttcctcatt tctgagtaaa ctctacaata attatatcaa
      481 agaaatgagg agttttgaat gttattattg attggactta ttttattaat tataggaatc
      541 actaaactgt cgaaagctaa cacaataaaa aaagaagctt atgaattaga acaaaaaaat
      601 gatgaaaaac taaataaatt acatgataga gaaagattta tattaagtaa ggaagaaaca
      661 ctatcagatt taaataaaca aattactatg ttaaaaaatg at
//
LOCUS       DAZUJR010000217          586 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.225, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000217 DAZUJR010000000
VERSION     DAZUJR010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..586
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.225"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..446)
                     /locus_tag="ACG804_002988"
     CDS             complement(<1..446)
                     /locus_tag="ACG804_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4833825.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRK"
BASE COUNT          177 a          106 c           77 g          226 t
ORIGIN      
        1 aactttctct tttcaaaaaa aatttgatat ttttttagat ttctttttag tctttgtaat
       61 actttataag ccacagaata actcacgtga tgctgtttag caaaattttc tactgagata
      121 tatttttcct gaaagaaagc caataccatt ttcatagata aagaatccgt tatataacga
      181 gataacagag ctttgctaga acattttcca ttaatttcca gacatatatc caattcactg
      241 acggttactc gcaaattttt ctctagatcg aacttttgta aatcatgttt cagcttatcg
      301 atcgtttttt tcaagagaaa tgtcgatagc gacaactctt cttgaacatt cgatattgac
      361 tctgataaat ttgagcttgc ttctaaatat ttaagtaatg aataacttct gtgatcttct
      421 ttgcttaaaa aaaactcata attcattagt catcagctct ttctacgtat attactttcc
      481 atgcattcac caactagctg gggataaaac tgatttcctg gatccgagtc actgttgtca
      541 gcgattcttg tttgtataat atacatcgtc ctgtcttttt tttaac
//
LOCUS       DAZUJR010000218          575 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.226, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000218 DAZUJR010000000
VERSION     DAZUJR010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..575
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.226"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            258..575
                     /locus_tag="ACG804_002989"
                     /pseudo
     CDS             258..575
                     /locus_tag="ACG804_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
BASE COUNT          195 a          105 c           82 g          193 t
ORIGIN      
        1 ttttacactc tctattattc ttttcataaa tattgtaaat agaagtatta aaaatatata
       61 caaaaagtat tatttcgaga aagataaata ttttcaaaaa ccttttcata atcctcaccc
      121 tttcttacac tgataaatca tgcgtctaat attcaaatta tactcgatat gctttagcta
      181 atcagccaac tctgtttgtc tactatcatt atatcaatag acaatatctg ctcccgtctt
      241 tatgatcgtg ccaaagcaat caaaagaaaa ttgcgaatca cttagatcga aagtttactc
      301 aaacaaaagc attgtcagcg gttgtcacgg atttaactta tgttcgggtc gggacaaatt
      361 gggcttatat ttgtttgatg attgatttat tcaatcgtga aattattggc cattcttgcg
      421 gaaataaaaa agatgcgcag cttgtaaaaa gggccattca aagcattcct tactcacttc
      481 aagaaatcga actcttccat acggatcgtg gaaaagaatt tgataaccaa accattcaga
      541 atctcatgaa tggtttggtt atcaaattcc tttcc
//
LOCUS       DAZUJR010000219          569 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.227, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000219 DAZUJR010000000
VERSION     DAZUJR010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..569
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.227"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>569
                     /locus_tag="ACG804_002990"
     rRNA            <1..>569
                     /locus_tag="ACG804_002990"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          139 a          131 c          173 g          126 t
ORIGIN      
        1 gagagtggaa ttccatgtgt agcggtgaaa tgcgtagata tatggaggaa caccagtggc
       61 gaaggcggct ctctggtctg taactgacgc tgaggctcga aagcgtgggg agcaaacagg
      121 attagatacc ctggtagtcc acgccgtaaa cgatgagtgc taagtgttgg agggtttccg
      181 cccttcagtg ctgcagctaa cgcattaagc actccgcctg gggagtacga ccgcaaggtt
      241 gaaactcaaa ggaattgacg ggggcccgca caagcggtgg agcatgtggt ttaattcgaa
      301 gcaacgcgaa gaaccttacc aggtcttgac atcctttgac cactctagag atagagcttc
      361 cccttcgggg gcaaagtgac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt
      421 tgggttaagt cccgcaacga gcgcaaccct tattgttagt tgccatcatt cagttgggca
      481 ctctagcaag actgccggtg acaaaccgga ggaaggtggg gatgacgtca aatcatcatg
      541 ccccttatga cctgggctac acacgtgct
//
LOCUS       DAZUJR010000220          556 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.228, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000220 DAZUJR010000000
VERSION     DAZUJR010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..556
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.228"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            131..529
                     /gene="spxA"
                     /locus_tag="ACG804_002991"
     CDS             131..529
                     /gene="spxA"
                     /locus_tag="ACG804_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SpxA"
                     /protein_id="HFS4833826.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT          196 a           87 c          110 g          163 t
ORIGIN      
        1 ttttttaaaa aaattatgaa aaaaaggtag ctatttaaaa gttgattatg tataatagaa
       61 acagatggga gattattatg atcttctgtt acaaaaaagt gattcttatc acgaaaagga
      121 gtggtgcacg ttgttaacat tatatacttc cccaagttgt acttcctgca gaaaggctcg
      181 tgcgtggttg caagaacatc agattccatt tgttgaacgt aatatttttt cagaaccatt
      241 gaacagttct gaattaaaag cgattttaca aatgacagaa gacggaacag aagaaatcat
      301 ctcgacacgt tccaaagtat tccaaaaact gaacatggat ttagatgatc tgccgttaca
      361 agaattattg gaacttgtgc aaaacaatcc tggattgctt cgccgtccaa tcatgattga
      421 tgataaacgt ctgcaagttg gttttaatga agatgaaatt cgtcggttcc taccgcgcga
      481 tgtacgacaa ttagaattac gtcaagcaca attgatggct ggattataga aggataatac
      541 gaaacttgga aaagac
//
LOCUS       DAZUJR010000221          514 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.230, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000221 DAZUJR010000000
VERSION     DAZUJR010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..514
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.230"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..132)
                     /locus_tag="ACG804_002992"
     CDS             complement(<1..132)
                     /locus_tag="ACG804_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFS4833827.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          186 a           94 c           92 g          142 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatcacac aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa
      481 tctagaaaca ttttgaataa aaactattag acaa
//
LOCUS       DAZUJR010000222          508 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.231, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000222 DAZUJR010000000
VERSION     DAZUJR010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..508
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.231"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
BASE COUNT          228 a           70 c           81 g          129 t
ORIGIN      
        1 aattccttag gcagcttttg ctgtgtagaa aggaataaat aataacgaaa gttcaaaagc
       61 taatgccgac tattctagac attaaagaag acgaaaacga acgataaaga aagaaaagtt
      121 atgaataatc gtttattgaa aaaaacttga aaaaatacaa aaaattcgtt gaccaagcta
      181 aatttagttg gtatattatt acttgtccaa aagacagaag aaaatattta ttcaaaaaca
      241 taacaaaaaa gttattgaca tgttactaac gacatgataa gataactgag tcgttaaaaa
      301 agaaccactt gcgaagcttg attctatcga aaaaaacttc aaaaaagttc ttgacaaata
      361 acaaacgata agttatgata aatgagttgc cgaaagattt cgaaaaacga aatcgaaaaa
      421 aacttttaaa aaagagttga caatcgcttg tctctctgat atgatataaa agttgctacg
      481 gcagccaaaa atgaatcggg aaacactc
//
LOCUS       DAZUJR010000223          476 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.232, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000223 DAZUJR010000000
VERSION     DAZUJR010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.232"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            22..>476
                     /locus_tag="ACG804_002993"
     CDS             22..>476
                     /locus_tag="ACG804_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFS4833828.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNF
                     LKCGGTALEYFEQYKENKRRCGRTEIIFPAEEKEYIEKRSTEGWTPDVIIGRAERTFS
                     CSVSTLYRRFKTGEFNVLHLPMQGKRKPNGYKEKRGKQAFKRNISERKK"
BASE COUNT          178 a           87 c           95 g          116 t
ORIGIN      
        1 atacaaggag agtgaacata aatgacttat acccatctta caccaaacga gcttgtaatg
       61 atagaagcat attttcatca agaaactccg gttgctatcg ttgcgaagca gcttaaacgt
      121 ggacgccaaa caatttacaa tgtctataac tttctcaaat gtggtggaac agcacttgaa
      181 tactttgaac aatacaaaga aaataagcga cgttgtggga gaaccgaaat catttttcct
      241 gctgaggaaa aagaatacat tgaaaaaaga tcaactgaag gttggacccc agacgtcatt
      301 attggccgtg cagagcgaac cttctcttgt tcagtaagta ccctctatcg ccggtttaag
      361 acgggagaat tcaatgtttt acatttaccg atgcaaggaa aacgaaaacc aaatggttat
      421 aaggaaaaac gtggaaaaca ggcattcaaa agaaatattt ctgaacgtaa aaaaga
//
LOCUS       DAZUJR010000224          450 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.denovo.233, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000224 DAZUJR010000000
VERSION     DAZUJR010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 450)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 450)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..450
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.denovo.233"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>450
                     /locus_tag="ACG804_002994"
     CDS             <1..>450
                     /locus_tag="ACG804_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS982-like element ISEfm1 family transposase"
                     /protein_id="HFS4833829.1"
                     /translation="INGYTSQRATYRAVCSVLFPNGDFPSRSRFTRLSSNLAYTIKII
                     RYFFIKKLTKGELVGIIDSFPSPLCKPVRNRQAKLLNQIAKVGYNSTKKSYFYGLKIH
                     MIVTKTGFPITYSITNPGVHDVKVLETLSEEANLPNILGDKGYISHK"
BASE COUNT          152 a           84 c           77 g          137 t
ORIGIN      
        1 taattaatgg ctatactagc caaagagcca cgtatagagc ggtttgttcc gtcttatttc
       61 ctaatggtga ctttcctagt aggagtcgat tcactcgctt aagttcaaac ttagcttaca
      121 ctatcaagat tattcgatac tttttcatca agaagctcac caaaggtgaa ctagtcggaa
      181 ttatagatag ttttcctagt ccattatgta aaccagttag aaatagacaa gcaaaactat
      241 tgaatcaaat agccaaagtt ggctataact caacaaaaaa atcttatttt tatggtctta
      301 aaattcatat gatcgttact aagactggct ttccgattac ttactcaatc acgaatccag
      361 gtgtccatga cgtgaaagtg ttagagactt tatcggaaga agcgaatctt cccaatatcc
      421 taggggacaa aggatatatt agccataaaa
//
LOCUS       DAZUJR010000225        10193 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.guided.095, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000225 DAZUJR010000000
VERSION     DAZUJR010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10193
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.guided.095"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(353..1225)
                     /locus_tag="ACG804_002995"
     CDS             complement(353..1225)
                     /locus_tag="ACG804_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFS4833830.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            1353..1922
                     /locus_tag="ACG804_002996"
     CDS             1353..1922
                     /locus_tag="ACG804_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DapH/DapD/GlmU-related protein"
                     /protein_id="HFS4833831.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLLVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            1989..2726
                     /locus_tag="ACG804_002997"
     CDS             1989..2726
                     /locus_tag="ACG804_002997"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFS4833832.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            2957..4225
                     /locus_tag="ACG804_002998"
     CDS             2957..4225
                     /locus_tag="ACG804_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFS4833833.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            4712..5176
                     /locus_tag="ACG804_002999"
     CDS             4712..5176
                     /locus_tag="ACG804_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFS4833834.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            5160..5789
                     /locus_tag="ACG804_003000"
     CDS             5160..5789
                     /locus_tag="ACG804_003000"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFS4833835.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGVEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            6143..7621
                     /gene="msr(C)"
                     /locus_tag="ACG804_003001"
     CDS             6143..7621
                     /gene="msr(C)"
                     /locus_tag="ACG804_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HFS4833836.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            7668..8114
                     /locus_tag="ACG804_003002"
     CDS             7668..8114
                     /locus_tag="ACG804_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HFS4833837.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(8313..8828)
                     /locus_tag="ACG804_003003"
     CDS             complement(8313..8828)
                     /locus_tag="ACG804_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFS4833838.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            8945..10147
                     /locus_tag="ACG804_003004"
     CDS             8945..10147
                     /locus_tag="ACG804_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4833839.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         3243 a         1786 c         2112 g         3052 t
ORIGIN      
        1 ttgattttca tgcgcgcacc ctttttgaag atttggtttt cacgtttgct agaccagttg
       61 attgcggcca aacaaaaata gacacgaaaa acctcctagg gaaaccatgt tcctcagaga
      121 tttttcatgc ctagtatgat ctagtcacat gaaacgaatt attgttaacg taatcaattt
      181 tatatagaca gttatgtttt gtcaattctt tttttataat tatagtaatt tactggaatt
      241 atcagaaata aaaggaagaa ataaattaag aaacttatgt tatttaatcg ttggatcttt
      301 tgcttatctt attcgttgtt aaaaagctga aagcgaagga aaaaaactct acttaactgt
      361 atttctccgt taggacatct aaaaatttac gagcagcagg agaaagaggc tggtcttttt
      421 tccaaatgag attcagtgaa gcttgtaatg gcggatcgag tgggatgaat attttttccg
      481 tcccataagt attgatgatc ccatctagag ctaatgcacc aaaagtcccg ttatcgacca
      541 tcaaagaagc attgtacaat aagttatatg ttccgacgat cgataactga tctatgctga
      601 aacctagcca ttcagctagt tgactgtcca ctgacgtttg ccgggaaatg atcaaaggaa
      661 cagttttcag ttcctgcgga tggatgacgg tttgctttgc taaaggatga tttcgatgta
      721 tcaaaagtcc ccaacgatct tgggctggca gtcgaaatga ctggtatttt tgtttgtttg
      781 tcggttcgat tacgagtcca aaatcaagta atccgctatc cagtttgtct atgatatcat
      841 ctgcattccc gctatataaa tgaaactgga tatcaggatg cgccttgatc aacgaatgaa
      901 ggctatcaga aatgaaagag attgctttag tttcgcctcc gccaatgtag atttctccag
      961 agatgattgc gtcatttgtt aaattgttcg ccgttttttc taccaacgac aagatttctt
     1021 ttccttttga ataaagatat cgaccagaat ccgtcaactg tatctctcgg gagccccgag
     1081 tgaaaagtgt cacaccaagt tcttcttcta aatctttcag ttgttttgag agagtaggtt
     1141 gcgtgatatg cagagatttt gctgctcggc tgatattttt ttctctagct actgctaaaa
     1201 aatacgtcag tatacgaata tccatttttt ccctcctgtt tttaaaaaag cataccacta
     1261 agtatagtta aaaggaatag ttaagtatgt tttataagta ttagacatga taagccgtcc
     1321 gttataaagt aaggataaaa ggagggagca aaatgacaag cctcatcgaa aaacaaatcg
     1381 tcaataaaga gattcgagta acggatccgc tctttgaagt gatccatcag atccaagctg
     1441 aaaacgaaga gcctttagca gcgctgaata ctgggtacca tgaaccagca gatatccgca
     1501 aacggctaga aaatatcatt agtgacaaag tagatgatac ggtgactgtt ctgctgcctt
     1561 tttatacaga tttcggcaaa catattagta tagggaaaaa tgtctttatc aatcgtcaag
     1621 tgatgttcgt tgacttaggt ggcatctgtt tagaagattc agtattgatt ggtcctcgtg
     1681 tcaacctcat cacggtgaac catctaaccg atccaaaaga acgaagaggc ttgttagtaa
     1741 agccaatcca catcaagaaa aatgcttgga tcggagcagg agcaactatt ctgccaggcg
     1801 taacgattgg cgagaatgcc attgttgcag cgaatgcaac tgttacgaaa gatgtcccag
     1861 acaataccat cgttgcagga atccctgcca aaatcgtcaa acctgtcgaa cggattattt
     1921 gaacagtaag atgaaataag agatagtgag tataagcaag agatttttca aaacaggagg
     1981 agaatagaat gaatgattta tcagaaaaag tgattgtcat catgggcgct tcaagcggaa
     2041 tcggtgaagc aacaacgaag ctattagcag aaaaaggggc taaactagtt atagctgcac
     2101 gccgagaaga tcgcctaaaa gcaataaaag aatctttacc agaagctgag ctatatattc
     2161 aaacagcaga tgtaagagat tttgcacaag tccaagcagt tatcgattta gcgatggaaa
     2221 agttcggtcg aatcgatgta ttgtacaata atgcaggaat catgccaacc gctccattag
     2281 ttgaaggtca ccgtgatgaa tggcaaaata tgcttgatat caacatcatg ggtgtgttaa
     2341 atggaatttc cgccgtactt ccaatcatgg aaaaacaaaa atctgggcat atcatttcaa
     2401 ctgattctgt ggcgggacat gttgtttatc ctgattccgc cgtttattgc ggaacaaaat
     2461 ttgctgtccg tgcaatcatg gaaggattac gtcaagagca acggcaaaat aacatcaaat
     2521 ctacgatcat ctctccagga gctgttcaaa ctgaattata tcaaaccatc agcgacaaaa
     2581 aggctgctct tgaacttcat gaagcgcaaa aagaatgggg attgacctcc gaagatatag
     2641 cttctgctgt agcatttgcg atagaaacgc cagaccggat gtctgtcagt aacatgatta
     2701 tccgtccgac gacacaggaa gtataatcca taacggataa tatccaaaga gaattacttg
     2761 ttaaatagtt attcaaacga ccatcaattt aaggcgtgaa tggagaagaa tattcttcat
     2821 ttacgtcttt ttatgtagaa aaagcaaatt tatcaaaaag aaacaaatgt tatttaaata
     2881 tggacattga cttgctttta cttttttagt tacactgtta tttaggaaaa gtttcataat
     2941 tcaaaggaga aaaaagatga aagcaaagaa tttattattt agcgttattc ttttaggaaa
     3001 tctagcagtt gccaacacaa cagtgctagc tgaagaatcg acagaaactg tcgcaactca
     3061 gacatcgagt tcttcagaaa caggaattga aaacgataca gagagtactt tgcagtcagc
     3121 tactgtctca gaaaatacaa tttcaaccga agaaccaaca actgaaacaa cagaacaaac
     3181 acaaaccgaa gacagtacat cagcagaagc tcagaacaat ccagagaatg cagaagaaat
     3241 cacgaaccaa ttgacagatg ggcaaacatt gacacatacc catcaagcag atttgtctga
     3301 attcgaaaac tatactggct atgcttttta tgctcgctca tctgctaatt ctcaacaagc
     3361 gttcattgat agtattgcct caactgcaca aagtttggca agtgccaatg acttatatgc
     3421 atcagtcatg attgctcaag ccatcgttga aagtggctgg gggaacagta ctttggcttc
     3481 tgcccctaat tacaatctat ttgggattaa aggaagctat aatggccaat ctgttacgat
     3541 gcctacttcg gaatatgtga atgggcaatg gattacggtg aatgccgctt ttagaaaata
     3601 tccttcgtac aaagaatcat tgcaagataa cgtaacggta ttgaagacga cttcttttca
     3661 gccaggcgtt tactactatt ccggtgcatg gaaaagcaat acgaactctt acaaagatgc
     3721 tacggcttgg ctaacaggtc gttatgccac tgcgcctaat tatggttcta cattgaacaa
     3781 tgtaatcgaa acctataatc tgacacagta tgatacagca ccaacttcaa cttctccgat
     3841 gtatcgtctg tataaccgtc atacaggaga acatttatat acattgaatg ccggagaaaa
     3901 aaattatctg ccaactgtag gctgggaata tgaagggatt gcttggcaag caccaaacag
     3961 cggacaacct gtctaccgtt tatacaatcc ttacagtgga gaccatcatt acacaatggc
     4021 acaatctgag atcaactctt taacaaaaat cggttggcgt tatgaaggtc taagttttta
     4081 ttctggtggt tccaagccaa tttatcgact atttaatcca aatgaaaaaa ctggtaccca
     4141 tcactatacc ttgagtgcta aggaaagaga ttggctaaca ccgatgggct ggagatatga
     4201 aggaatagga ttttatggtt attaaaaaga ggtagtgaaa aagctgccct gcatcaagta
     4261 gtaagaacag ccaaacaaaa acagattttc atgttttttg tttggttgaa cttattaccg
     4321 cagatgcaag tttttgaaca ccgtttactc aaaaaaggtt gtgacaacat cttgtcataa
     4381 cttttttatt actgtttaag catactgatc caatttctaa tattcgacgg gattcttgca
     4441 aaaggcgatt tcggaaattt ttggcggtgt aaaattttct actgcagaag agctatcttc
     4501 tatagtttga taagaatcaa taatcttggt tttagcgttg tgctttcttt atcatttttt
     4561 ccgttcattc tacaaaaaat ttcttttctc tatacttttc tattgagagc gtttttttta
     4621 ttacacagct gattctttga cttttttctt tttttattct attattgaca agtcaatcgt
     4681 tgacgagtca attattagaa aggaggaaat tatgtcttta gaagagatta gtcacctttt
     4741 atatcaaatc aaattagccg atcaaaaaat cgtccagatc tttgaagaaa atatcggtat
     4801 aagtcttact agatacgaga tcatgatgag actgaaagaa gaaaatccat tgctacaaag
     4861 cagtttgcaa gaaaagttgc agattgatca aggagcagtt actcgtcatc tgaaggtatt
     4921 ggaagcaaat ggctatgttt cgcgtcagag aaatcctcag aacaaccggg aagtgtatgt
     4981 agcgctaaca gaaaaagccc agaagaaaat cgagcattgt gaaatggacc ataaagatac
     5041 aggttccgtg ctatccccgg ctttcagcga tgtagaaatg aaacaatttc taacactttt
     5101 agataaattg aatacccaac tttgcaatat aacaacagaa acgaaagagg ttaataataa
     5161 tggaacaaaa aaatgatttt tcaacaatta tgactggtag aagatccgtt cgcgtatatg
     5221 atgaaacata caaaatccca cacgaagaaa tgctggaaat gatcaaagaa gcgacgactg
     5281 caccttcttc tgtcaatatg caaccatggc gctttgtggt cgctgaaagc gaggaagcaa
     5341 aagaaatctt gcgtcctttg atccgtttca atacgagaca aaatgatact tcttctgcaa
     5401 tggtcatgat ttttggcgat atgcaatgtt acgaatatgg cgaagaaatc tataaccaag
     5461 cttacgaatc agggaagatg ccaaaagaag tcagagatca acaattagct gcgatcattc
     5521 cttattacaa gagtttttca agagaagaaa tgaacgatgt agtcaaagtc gattctagct
     5581 tagcggctat gcaattcatg ttagttgcgc gtgatcatgg ctatgaaaca aatccaattg
     5641 gtggagtcga agcagatcag ttggcagagg catttggttt ggataaagac cgttatgttc
     5701 cagttattat tttatcaata ggaaaagcgg tagaagaagg ttacgagtct gttcgtttag
     5761 caccagaaaa gatcactacg ttcgaataaa aggttttcag ttactattca gtagctattg
     5821 ctttttttga atcgtgtgtg gtaacctaat aaaaaaggag gtcggaaaaa tgactgcatc
     5881 gatgaaatta cgtttcgaac ttttgaataa caactaaata aattcaaaag acatgtataa
     5941 acaacaattt catggatgga gtatgtccat tttttcgaac gacagtagaa taggtgaaag
     6001 ctatgacaga tttggtgatt tagtcatagt tatttcgttc agagtaggaa aagatgtgat
     6061 gcagtttttt tgcaaacaga tttttctgct cttttttagt atcgataatt gttgttttac
     6121 atgaaatagg agtgtaaaac atatggaaaa tttagcagta aatataacaa atctacaagt
     6181 cagctttggc aaccagctag aactatctat tgattctctt cgtgtctatc agcaagatcg
     6241 tatagggatc ataggagaaa atggtgtcgg taaatcgact ttgctcaaac taatagccgg
     6301 tgaacttttt cccgatcatg ggaaaatcca aacagagatc accttcaact acctgcctca
     6361 attaacctat ctcgctgaag caaaggacct aaatttggaa ttagccagtc atttccagtt
     6421 aagactggaa gaaacttcag agcggaaatg gagcggaggg gaagaacgaa agatcgagtt
     6481 gatacgtctt ctttcttctt atgaacaagg gatgcttcta gacgagccaa caacccatct
     6541 agatagaaaa agtattgatc gactgattga agagcttcgt tattattatg gtacgctggt
     6601 ttttgttagt catgatcgct attttctaga tgagctagca tcgaaaatct gggaagtaaa
     6661 agacggagaa atccgagagt tttcggggaa ttatagtgcc tatctcactc aaaaggaatt
     6721 ggagaaaaag actcagctac gagaagcaga gtcgatcatg aaagagaaaa aacgattgga
     6781 aaaatcgatc caagaaaaga aaaaacaagc ggaaaagttg gaaaaagtgt ccagtaaaaa
     6841 gaaaaagcaa caaatcagac cggatcggtt gtcttcctct aaacaaaaag acagtgtaca
     6901 aaaagccatc caaaagaatg cgaaaacatt agagagaaga ctccaaaaaa taggagaaac
     6961 aaccaagccg cagcagatga aacaaatccg ttttccagta ccaaaatctc ttgaactcca
     7021 cagccgctat cccatcatgg gacaaaatgt ccaattggaa agaagtggga gaacattact
     7081 ggtaaatggt gattttcagt tttctttagg taaaaaaatc gcgattgtcg gtgaaaatgg
     7141 ttcaggtaag acaaccttat tagaacatat ccgcaaacaa ggagaaggaa tccttctctc
     7201 tccgaaagta agctttcaag tatatcagca aaagggttat caaatgacat ctgaagaatc
     7261 catcattcgt tttgtcatga gacaaacaga gttttcagaa tcgcttgtcc gtagtttgct
     7321 gaatcactta gggtttgctc aggaaacttt gacgaaaccg ttatgtacat taagtggggg
     7381 agaagcgacc cgtctgacga ttgctttgct ttttactaag ccaagtaatg tgttgctgtt
     7441 agatgaaccg actaatttta ttgatatggc aacgatcgaa gctttagaga agctaatgca
     7501 aatatatccg ggaacgattt tgtttacttc tcatgattct tactttgtcg agcgtacggc
     7561 tgatgaagtt tatgaaataa aagggcagaa aataaaaaaa gtacttacga gaaattttta
     7621 aatgtgctac gatgattttc gtgacaaatt taaaggagtg gtacagattg cctacaaata
     7681 aaaaagaagg aataattttt acaacaatga tgtgtttttt gatggtcttg gggatgagcg
     7741 cgtataattt atggctgcat caagatcttc atttatcaag tttgttgatt ggtctagtgc
     7801 ctggattcgt ggtggctttc attttggatg tcttcatcat cggtgtgctg gcgaaaaaaa
     7861 ttgcctttaa actaccagta aatccagaaa gcaaggtcca aatgatctta actatttcat
     7921 gcttgatggt tttaggaatg gtgacatgta tgtctttatt cggtgtgatc atggaacaag
     7981 gaatacctga tcaattattc tctgcttata tgaatgcttg gaaaatgaat gtgattgccg
     8041 ctttaccgtt gcagttgatc atcgttggcc cgctttcaag aagtgtgcta aaagcaattc
     8101 aaagtaatga atgatggaac actgttattt gaaaaaaggc cttggcatgc tttttgtcat
     8161 agtctcttga atgcagttct agaaaaatag tgatccgaac gataggtttt ggcctgtcgt
     8221 tcggatcgct ttttcttttc caactgtatt gctcttttat tgaagataat ttgctcttca
     8281 atagatattt ctagaaaggt tctgtttatc ccttactcaa aaaactgctg catttgttct
     8341 cttacttgct gacaccattg gagttcctgc tgacaaagca taattctgcg ctggatcaca
     8401 acataacgtc caaattcttg tttcttgtct agcgagaggt cattcaattt tttttgattt
     8461 ttttgcatga ttttgttcag ctgttgttct ctagtgaata gcagtccagt agctgttgtt
     8521 ttatcgagcg tcgaaaaagc atagattttt gctagaaatt catctttttg cgtaggagcg
     8581 ggagtttcct ctttgatcca ttcctctaca agagcacgtc cttcatcagt caagtggtag
     8641 atcttttttt gagagtgctc gtctttgtcc aaaacggtca cataaccctg ctggtctaac
     8701 ttggcaagcg ttgtatagat ctgactgtga tgggcttccc aaaaaattgt gatcagctgc
     8761 ttcaattcat acccagaacg tggtttggat aaaagcacgc ataataatat ataggctaaa
     8821 gtattcataa aaatcctacc tctcgtctta ttttctttat tatatcacag taaagtttcc
     8881 acgttttaca tgtgcatatt tacatgtaaa ataaatcatg tatgatgcta atagagagaa
     8941 agggatggaa atattggaga atcaaataga tatacaagaa caaacaaatg aagaaacaaa
     9001 ggggaaaagt tcagcgctag ttgtagcagc tacctgtatg atcgctttta tgggagtggg
     9061 tctagtagac ccaatcttaa aaacgattgc tgcacagtta aacgctacgc cagctgaaac
     9121 gaccctgtta tttactagtt acatgttagt cactggtgtg gtgatgctat ttacaggttt
     9181 cttatctagt cggatcggtt tgaaaaaaac attgatgaca ggattgttta tcatcgttgt
     9241 attcgctggt cttggcggat tatctgggaa tatcggaatg ctgattgggt tacgtgccgg
     9301 ctggggtgtc gggaatgctt tatttgtctc tactgcttta gcaacgatcg tcagtatttt
     9361 agttggtaac acagaaaaag caatcatgat gtatgaagca gcacttggct gcggaatggc
     9421 tgttggccct ctagtcggtg gggtcttggg cagtggttca tggcgttatc cattttttgg
     9481 ggtagcattt ttgatgtttt gcggttttat agccctagcg gtacttttac ctgaaactga
     9541 gaaaccaaag agaaaagtag gcctttggga aggtgtcaaa gcgttaagca atcataaact
     9601 tcgttcagtt ggactaatcg cattgttata taatttcgga ttctttactt tacttgcgta
     9661 tgcgccattt ttattgattg gctattctga attagaagtc ggttttgtat tttttggctg
     9721 gggtgtgctt ctggctattg cttcgatttt cgttgcaccg gctcttgagc ggaagtttac
     9781 gacttatcgg acaattttag cagcatttgt cttattcatt atttgtttgc tgttattagg
     9841 agctggaact tctatgccag tccttgtacc gatcagcatt gtgttagcag gatttttcca
     9901 aggaattatc aatacactgt tgacgacgat tgctatggaa ataccaggtc tgcaacgaaa
     9961 cgttgcttcg tccagctata gttttgtccg ctttttcggt ggagctttag caccatttat
    10021 tgcaggtgtg attggtgaac atattggtga aagctatgcg ttttattttg caggtgccat
    10081 tgttcttatc agtgtatgtt gtatcattta tcaccgtaat tattttgcta caaatgaaga
    10141 agaataagaa atcagaggtt gtgaaaaagc tgtcctgcat caagtcataa gaa
//
LOCUS       DAZUJR010000226         9664 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.guided.097, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000226 DAZUJR010000000
VERSION     DAZUJR010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9664
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.guided.097"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..199
                     /locus_tag="ACG804_003005"
     CDS             <1..199
                     /locus_tag="ACG804_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HFS4833840.1"
                     /translation="RPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKRF
                     ITNDSTIYEQYEYDLSSVENK"
     gene            complement(349..1290)
                     /locus_tag="ACG804_003006"
     CDS             complement(349..1290)
                     /locus_tag="ACG804_003006"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HFS4833841.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            1416..2537
                     /locus_tag="ACG804_003007"
     CDS             1416..2537
                     /locus_tag="ACG804_003007"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFS4833842.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            2795..4297
                     /gene="eat(A)"
                     /locus_tag="ACG804_003008"
     CDS             2795..4297
                     /gene="eat(A)"
                     /locus_tag="ACG804_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HFS4833843.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            4364..4891
                     /locus_tag="ACG804_003009"
     CDS             4364..4891
                     /locus_tag="ACG804_003009"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFS4833844.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            5102..6163
                     /locus_tag="ACG804_003010"
     CDS             5102..6163
                     /locus_tag="ACG804_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HFS4833845.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            6166..7062
                     /gene="murQ"
                     /locus_tag="ACG804_003011"
     CDS             6166..7062
                     /gene="murQ"
                     /locus_tag="ACG804_003011"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HFS4833846.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            7076..9058
                     /locus_tag="ACG804_003012"
     CDS             7076..9058
                     /locus_tag="ACG804_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose PTS transporter subunit IIA"
                     /protein_id="HFS4833847.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(9123..9569)
                     /gene="nrdI"
                     /locus_tag="ACG804_003013"
     CDS             complement(9123..9569)
                     /gene="nrdI"
                     /locus_tag="ACG804_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HFS4833848.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
BASE COUNT         3139 a         1723 c         2100 g         2702 t
ORIGIN      
        1 tcgtcctgaa aatatttttt tgcttcgaga acgtgattta gatgaattac cggaatttct
       61 gcatacacca tttaagccaa tcctatcaga gctattggaa ttttatgatg cagaaaattg
      121 ggcaaaacga tttatcacta acgattccac tatttatgag caatacgaat atgacctctc
      181 ctctgttgaa aacaaataaa aaacctacat tttgaagaga ttatgtactg aaacaaacaa
      241 gcacaattct tatggcatca tgagagttgt gttttctttt tgatctttta ttgggcttaa
      301 aaaaagagaa ccagctgctg attcagctga ttctcatcag agagcctttt attctgcgcc
      361 aaggattcct tcttttgcat ggactaattg ggtcaaaaag gcacaatatg gtgtagcaat
      421 atcatatttt tgtccttttc gccaaatggc accattgatg tagtcgattt cagtcaaacg
      481 atggtttttg atcaggtctt ggtacataga tgggtaatgc aacccgatgt tgtcaggatc
      541 ataagtagaa gcaatatgtt ggtacacttc ttcttgatct agtatgattc cttcttttgc
      601 tgcgatagaa gcaaattcag atacgattgt tcgaaccatg ctctctgccg ctttttgcgc
      661 gcctagttca gcaatattac aatccaaaat cgtgcataaa ccattcaatg ttccatttac
      721 acaagctttt cgccaaatgg aataacgaac gttatggcta tagatcggat ttaaatttgc
      781 ttcttgaaag acttctacaa ctttttttgt aaatgcttcg ccttctggtt ccaagttctc
      841 tagttcgatt tctccatcac ctaacaatgt gacttttccg ggaccagcta gaccagctgt
      901 ccacatcgtg atcccaaata agatattttt ctttggcaca tatttttcca gtacatcttc
      961 atgacctaat ccatttagta aacacaaaac ataagtattg tcagtaataa tggattggat
     1021 cgaacaaaac atatcatcta attgattggc ttttgttaat gctacgatca agtccacgtg
     1081 ttcgttgctt tcgatgattt cttctggtga atagattggc agttttgcga ccacttcttt
     1141 accgttaaag tcagcaatca acccatttgt acgaatggct tcaatgtgag caggccaacg
     1201 atcgatcaag aggacctcat ttccgctttg atgtagcatc aatccgattc ggctgcccat
     1261 tgctccggcc ccagctattg cgattttcat gttttttctc tcctttattc aatgagttcc
     1321 cttttagtat atagaaaaat ggaagaaaat agcattgttt tgtttgaaaa aaatgaaaaa
     1381 aagtgtctta cttaagaaga aagtgaggga tacagatgga tattttggcg gcaattgatt
     1441 catttaaagg aagtgcttct tcatttgaac taaatcaggc agttctaaat ggctgggaag
     1501 atcgtaaagg aagaaaaatc aatgtgccga ttgcagatgg cggagaaaat actgcagaag
     1561 caatctatta cgcgctcagg ggaacatggc gtaccattga tgggatggat ctcttattcc
     1621 gtcagcgaaa aatcagctat ttattgacaa cttggcaagg aaaaaacacc gcagtcatcg
     1681 aatctgcaca agcattgggg ttagatctac ttgataaacc aacggatcaa actatccgac
     1741 ttgcttccag ttatgcctta ggagaactta ttaaagatgc actgcttcaa gaagtagaac
     1801 aaattattgt cactttagga ggaagcgggt gtagcgatgg tggtctagga ttactccaat
     1861 ccttgggtgc ttctttagaa gggtacacag aaggaaatcc tttattatct actaaaaaac
     1921 ttcattttga tcgaagaaac gttcttgttt ctaaagtaaa attgattatc gctgcagatg
     1981 ttaccaatcc atatacaggt caacaaggag ctgcttggca atttggaaga caaaaaggag
     2041 gaatagatac gacgctagct ttcttagata aacaagcagg aaagattgct cagcaaataa
     2101 aagatttctg ggaggtggat ttagatgata ttccaggaag tggagcagca ggcggtattg
     2161 gtggagccct ttttttgttg ggagcgaaga tggtttctgg tttcgattta gtcagccaaa
     2221 tcactggatt ggaaaaaaag atcgaacaag cagatgtcat cattacagga gaagggcgga
     2281 tcgatcagca aacgatccac ggaaaagttc catacggtgt agcagtgctt gcaaaaaaat
     2341 atcgaaaacc aataatcgct atttgcggaa gtagagacca agagctagaa ggactttctg
     2401 attttctccc aattgtctta agtattcatt tgggtccaat aggtttagaa gaagcaatgg
     2461 aacacaggca aacattagaa aaaacaaaaa tcttaggaca gacacttagc agatttttca
     2521 ccatcctccc gaagtagttg acaaaatcat tttctttatg ctatcgtaat ttcaaatata
     2581 ggacaaagtg agggatccgt gcattgaaaa attaagtcga ttgatgaaag ctgcattcag
     2641 actgtacctt gtggagacaa ggaagcagtg tgcagatttt cgggattggc ttggtttttt
     2701 cgatgtatgg gtctttttgt gtgtatccaa cccttgcatc ctctttagcc agttctgaaa
     2761 ataggactgg tcttttttta cgaggtgatg gaaaatgtct aaaatcgaaa taaaaaatct
     2821 gacattcggc tacgacagcc aaggcacatt attatttgaa caagcaaatc taaattttga
     2881 cacacaatgg aaactaggac ttatcggacg aaacggtcga ggaaagacaa ctttactgaa
     2941 tattctacaa aacaaactac cttatcaagg gcaagtaatc catcagcaag aatttgccta
     3001 tttcccgcaa cagacaaaag ataaagaacg tttaacctat tacgtgttaa atgatattac
     3061 ggattttgag atatgggaaa tcgaaagaga gctccaattg atgcaaacag atcctgaaat
     3121 cttatggaga gaattcagca cactatcggg gggagagaag acaaaagtcc tactggcact
     3181 tttatttgtg gatgacactc atttcccgtt aatcgatgaa ccaacgaatc atttggatat
     3241 ctctggtaga aaacaagtag cggcttattt gaaaaagaaa aaacaaggct tcatcgtggt
     3301 cagccatgac cggggattta tcgatgaagt agtggaccat gttttagcaa tcgaaaaaag
     3361 tcaactggaa ctttatcaag ggaatttctc tatctatgaa gaacagaaaa aacttcgtga
     3421 tgaatttgaa atggctcaaa atgaaaaatt gaaaaaagaa gtcagtaggc taaagaaaac
     3481 agcagctgaa aaagccgaat ggtctcgttc ccgagaagga gataaaacaa agaaacaagt
     3541 cggattcatc gatactgaat ctagacgagt gaataaagga gcagtgggtg ctgatgctgc
     3601 acggacgatg aaacgatcca aagcaatcgt gaatcggatg gagacccaga tcagcgagaa
     3661 agaaaaacta ttaaaagata tcgaatatat cgattctttg acgatgaata gccaagcgtc
     3721 tcaccataag cgacttttaa gcgtagaaga tcttcaatta gggtatgaaa atctgttatt
     3781 cgagccaatt cattttacaa tcgagcctca tcagcgggtg gcgatttcag gtcctaacgg
     3841 tgcaggaaag tcatccatta tccattatct tctgggggca ttcaacggca aggttatagg
     3901 agaaaaatac cagccaaaac atctgagcat tagttatgca agccaaaatt atgaagacaa
     3961 tcgaggaacg ttggcggaat ttgcagagaa aaaccaagta gactaccaag catttttgaa
     4021 caacctccga aagcttggga tggaaagaga tgtttttcat aacaagatcg agcagatgag
     4081 tatgggccaa cggaaaaaag tggaattggc taaatcttta tcacagccag ctgaactata
     4141 tacatgggat gaaccattga attatttgga tgtcttcaat caagaacaat tagaacaact
     4201 gatcttgaac gtgaaacctg ccatgttact agtggaacat gatcaaacct tcctggataa
     4261 agtatctact gagattattt ctcttgagag aatctaaccc ttgtaatctc aagaacaaca
     4321 aggtatggtt aaggggaact ttgccaacga aggagagaat cacatgcttt atgtaacgag
     4381 acacggagaa acaacttgga acgcacaagg attagtttgc ggacgggcag atgtgccgct
     4441 gactgaaaaa ggacagatgc aggcacagaa actagcagaa aaggtagtag atttgcctgt
     4501 tccaatcacg aaaatcatcc attcccctct tcaacgagca agagatacag cacaagcagt
     4561 tgctgatcgt ctcagcttgc cgctgaccgt tgatgaacga ttggtagaaa tggattttgg
     4621 ggattatgat ggactgccaa gcaaagatga gaactttcaa aaagcacgtt tagcgttcgc
     4681 tgtacgattc ccaaatgggg agtcagtctt agatgtgtat gcacggatcg ttcctttatt
     4741 gaaagaatgc atcgaagacg aagaaaatgt ctatctgtta gtttgccata atgccttgat
     4801 aagagtgatc aatgcttatt ttcatccgat gcctaatgag gggttcttta cattcatggt
     4861 agataataca gaattggttt cttatgagta attatgtttt tgtgttattt aaataaaata
     4921 tttcaaggca ctgcttttgc ttagcagtgc cttttttagg ttatgacaat tcttttgata
     4981 atataaactc aacctttaga aatgaaattt aattatttta ataaaagtat tgaaattttg
     5041 tttctttaga tatatactct agtcatagaa atgaagacgg atacagaaaa agagggataa
     5101 tatgtttggc ttttcaatat ttatgaacga ttctttgtca gaagagaaga aacagtatat
     5161 ccgccaaatg gcatccaatg gctttgtcgg tattttcact tccatgcata taccagaaga
     5221 tgatgtttcg gcatatcaaa agcgattgat cgaactagga agcgaagcga aaaagaataa
     5281 actagaattg atggtcgata tttcaggaga ggcattggaa cgagcgggtt tttcattaga
     5341 agatctaacg cctttgaaag caattggtgt aacaggttta agaatggatt atcatatttc
     5401 caatcagcag attgccgact ggtcacatca attgaaaatc agtttgaatg ctagcacgat
     5461 cacgcctaaa gatatcgatg aattgaaaga agcagaagct gatttctcac agattgaagc
     5521 ttggcataat tattatccac gtcccgaaac agggctggac aaagaatggt atcagaaaaa
     5581 aaatcaatgg ctcaaaattc aaggtctcct tgtccaaggt tttgtaccag gagatacaga
     5641 gttgagaggc ccactatatc aaggattgcc aactttggaa gaacatcgag ggatccatcc
     5701 tcttgcaggc gctctagatc tattagcaag taacacggat attgtttaca tcggagatgc
     5761 aggtctgtca gaaaacgttc aggagcaatt tgcttctttc caaaaagaac agacagtctt
     5821 gctccatacg gaacctgtag atgaagaatt ttacgaatat atattaggga agcatacgaa
     5881 tcggcaagac gatgcaagag atgtcatacg aagcgtagat gcacgttttc gagagattcc
     5941 gcctatccca gcaagaaata cagctacgcg tatgaaaggg tctattactt tagataacga
     6001 aaagtatttg cgctatatgg gtgagatcca attaaccaaa tatgatttgc cagcggatga
     6061 aaaagtgaat gtagtagcta aagttatcaa agaagagcta ccattgatca accaaatcaa
     6121 agctggtatg aactatcaat ttataagaaa agaaggaaga taaaaatgag caaaatcaat
     6181 ttagagaacc taacaacgga acgcagaaac caagaaactt ttggattaga tgagatgagt
     6241 atttctcaag ccgttcaact aatgaacaaa gaagatcaga aagtggccgc tgcggttgaa
     6301 aaagaactga caagtatcga accagtgatt gctaacacga ttgagtcctt taaaaaaggt
     6361 ggacgtctga tttatatggg agccggaaca agtggaagac taggtgtgtt agatgctgct
     6421 gaatgcgtac cgacattcgg tgtagaaccg gaaatggtca taggtctaat tgctggtgga
     6481 gaagaagcaa tgactgtagc tgtcgaaggg gccgaagatt cttatgagct agggcaagaa
     6541 gatctaatca agctgaattt gacaaaaaat gatatagtta ttggtatcgc agctagcggt
     6601 cgtacaccat atgtgatcgg tggattagat tacgcaaaat cgatcggtgc tgtcacagga
     6661 acgatttctt gcaataaaca agccgaaatc agtaaacacg cggatttccc aatcgaagtc
     6721 gatgcaggtc cagaattttt gacaggctct actcgattga agtcaggaac agcacaaaaa
     6781 cttatcttga atatgatttc tactatcagt atgattggta taggtaaagt attcaataac
     6841 ttgatggtcg atgtcaaacc aacaaatgaa aaactaatcg aacgctcaaa acgaatcatc
     6901 atgcaagcga cagaagctga ttacgaaaca gctgaaaagt actttgaaga agcagatcaa
     6961 aatgttaagc tggctatcgt catgattttg acaaatagtg ataaagagga agctcaagca
     7021 aaattagctg aagcaaacgg atttgtaaaa gggaccttat gagggggaaa agaccatggc
     7081 aaaaaacgaa ctgactttgg aagaactggc aaaacaaatt tataaagggg caggcggcat
     7141 gggcaatgta gaaagcattg tccactgcat gactcgtgtg cgtatgaaga tcatcaatga
     7201 tgatcttgta aatgtctctg aattaaaagc gattccagga gtgcttggtg tagtagaaga
     7261 tgaacagctt caagtcatca tcggacctgg gaaagtgaac aaagtagcac agcaaatggt
     7321 tgatttggca ggcgtgaaat taggagaaaa actttcttct gtaagtacag ctacagcaaa
     7381 ttcatcagca tctggaaaag accgtgtaaa cgaacgggca caagaaatga aagcggcaca
     7441 aaaatcgaaa caaaaaccat ctaaaatcaa atcggtatta aaagacattt ctaatatctt
     7501 tgtgccaatg attcctgcat ttgtcggtac tgggatcgtg gcagggattg ccgcagtttt
     7561 agcaaactta gtcacagccg gaacacttga tgcagcaaca tggcaacaat atatcgatgt
     7621 gatgaacatc ttgaaaaacg ggatgtttag ctacctagtt atctatacag gtatcaatgc
     7681 tgcacaagtt tttggtgcaa caccaactct tggtggagtt atcggggccg ttgtgatgct
     7741 gacagggatg aatccggaag caccactgaa aaacttattt actggtgaag ctcttgcagc
     7801 tggacaaggt gggatcctag gtgtcatctt cgctgtttgg ctattgtcaa tcgttgagaa
     7861 aaaactgcat aaagtagtac ctgatgcggt agatatcatc gttacaccaa ctctttcatt
     7921 gattgccatc ggtctgattg aaattttctt catcatgcct ttagcaggtt tcatttctga
     7981 tggcatggtc ggtgggatca actgggtact tggcgttggt ggagcatttg ccggcttcgt
     8041 tctaggcaca ttattcttgc cgatggttat gttcggactg catcaaattt tgactccaat
     8101 ccatgtgcaa atgattgatg aaactggtcg tacgctattg cttccaattc ttgcgatggc
     8161 tggtgcagga caagtgggtg cagcattggc attatggatt cgctgcaaaa aagataaaga
     8221 attaacagaa atgatcaaag gagctttacc agtcgggatc ctaggaatcg gcgaaccatt
     8281 gatttacgga gtaacattac ctctaggacg cccatttatt actgcttgta tcggtggagg
     8341 tatcggcggg gcagtgatcg gaatgatcgg aaatgtcggg gctatcgcta ttggaccttc
     8401 aggagccgct ttgatcccat tgatctctga cggtaaatgg ttaggctaca tccttggatt
     8461 attggcagct tatgctggtg gcttcgttgc tacattcttc ttcggtattc ctaaagaccg
     8521 tttagaaaaa gaagaattag cgactgaaac agccacagta aatgaagtgc ctgaaaaagt
     8581 agtacctcaa acttcagctg aaagtgtgac tatcctctca tcagttgctg acggaacagt
     8641 tgtttcttta gataaagcaa gtgatccagt ttttgcacaa aagatgatgg gtgaaggcta
     8701 ctttgtagaa ccagaaaacg gacatatcta ttctccagtt actggggtag tcagctctgt
     8761 cttcccaacg aaacacgcta ttgggatcac aacgccaaat ggtttagaaa tcttgcttca
     8821 tatgggaatc aacacagttg acttaggcgg tacgccattt gatgtgaaag taacagaagg
     8881 gcagcaagtg acacctgata cgcttgtagc agaagctgac ttagaagcga tcaaagcagc
     8941 aggcaaagaa acatccatga tcgtcttggt aaccaatatg gatcgtgtaa aaaactttgt
     9001 cttggaaaaa acaggtaaag caaaagcaaa agcacctgtg atggatgtca aagcttaata
     9061 tgatagaaac aatagaaacg aaagaagaaa ctgaaatcta tttttcagct tcttcttttt
     9121 tattatttat tgttttctgc taaaatctga taaattcgtg tcacatcaga tggtgttccc
     9181 cgtaattcat aatctgccaa gaaaggaaag ccaaatgttt gtgcatattg tttggctgtt
     9241 agacaatact gattattgaa gtttttattt ccgctaccga ctacaccaag acaaagttta
     9301 tgattgtctt catgttccag atattcacgc atcgtttcgg tcaagatttc tgtatcaccg
     9361 ttatctaaac catttccgcc gtctaaataa gtaggaacga aagtaaaaaa tggttctgtt
     9421 tctttcgtaa aatcactatt ttcatggatt tcttttaaag taacttcagg attgacagga
     9481 tcttctgcat gcattttttc agcatattct gctagatgtt tggcaaaggc acgcgtattt
     9541 cctgaaatcg atatatataa aatgttcatg gatcatcctc caattctttc cttttagtat
     9601 agcatctttt ttaagttttt tggtggtgta atttggaaag ggactaggcg ctttgcttgt
     9661 ataa
//
LOCUS       DAZUJR010000227         8650 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.guided.103, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000227 DAZUJR010000000
VERSION     DAZUJR010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8650
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.guided.103"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(202..573)
                     /locus_tag="ACG804_003014"
     CDS             complement(202..573)
                     /locus_tag="ACG804_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4833849.1"
                     /translation="MANIEDCPGFETFGADVKAARQAKRVSRKAMAEKINIDWRYLAN
                     IENDGAIPSLPVVIQLIKACGLPVERYFNPEIMREESELRQRVSHKLKLCPEEYLPII
                     EGAIDSAILIEKPKKNETEDV"
     gene            718..903
                     /locus_tag="ACG804_003015"
     CDS             718..903
                     /locus_tag="ACG804_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HFS4833850.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            1061..1228
                     /locus_tag="ACG804_003016"
     CDS             1061..1228
                     /locus_tag="ACG804_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833851.1"
                     /translation="MKKRNFIMTEMENARNKDEEAAAVSAVYGRIEKAGIWILYGEVS
                     RHWITAGLMRL"
     gene            1846..2505
                     /gene="vanR-B"
                     /locus_tag="ACG804_003017"
     CDS             1846..2505
                     /gene="vanR-B"
                     /locus_tag="ACG804_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-B"
                     /protein_id="HFS4833852.1"
                     /translation="MSIRILLVEDDDHICNTVRAFLAEAGYQVDACTDGNEAYTKFYE
                     NTYQLVILDIMLPGMNGHELLREFRAKNDTPILMMTALSDDENQIRAFDAEADDYVTK
                     PFKMQILLKRVEALLRRSGALAKEIRVGRLTLLPEDFTVLCDGTELPLTRKEFEILLL
                     LVQNKGRTLTHEIILSRIWGYDFEGDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEE
                     S"
     gene            2508..3851
                     /gene="vanS-B"
                     /locus_tag="ACG804_003018"
     CDS             2508..3851
                     /gene="vanS-B"
                     /locus_tag="ACG804_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-B"
                     /protein_id="HFS4833853.1"
                     /translation="MERKGIFIKVFSYTIIALLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPDFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQAQSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLTSTL"
     gene            4022..4828
                     /gene="vanY"
                     /locus_tag="ACG804_003019"
     CDS             4022..4828
                     /gene="vanY"
                     /locus_tag="ACG804_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-B/VanY-G family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HFS4833854.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGRR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            4846..5673
                     /gene="vanW-B"
                     /locus_tag="ACG804_003020"
     CDS             4846..5673
                     /gene="vanW-B"
                     /locus_tag="ACG804_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance accessory protein
                     VanW-B"
                     /protein_id="HFS4833855.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGEKS
                     LSHLLFETDCALYNHNTGFDMIYQENKVFNLKLAAKTLNGLLIRPGEPFSFWWLVRHA
                     DKDTPYKDGLTVTNGKLTTMSGGGMCQMSNLLFWMFLHTPLTIIQRRGHEVKEFPEPN
                     SDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKIIGQVSADKEPQALYKITNG
                     SIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKCKICYPLPESVDIQEENQ"
     gene            5670..6641
                     /locus_tag="ACG804_003021"
     CDS             5670..6641
                     /locus_tag="ACG804_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HFS4833856.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVGHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            6634..7662
                     /gene="vanB"
                     /locus_tag="ACG804_003022"
     CDS             6634..7662
                     /gene="vanB"
                     /locus_tag="ACG804_003022"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HFS4833857.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKSAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGTFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDS
                     LITLALKR"
     gene            7668..8276
                     /locus_tag="ACG804_003023"
     CDS             7668..8276
                     /locus_tag="ACG804_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HFS4833858.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
     gene            complement(8342..8515)
                     /locus_tag="ACG804_003024"
     CDS             complement(8342..8515)
                     /locus_tag="ACG804_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833859.1"
                     /translation="MLPEKNGGLDFSKPPPAKYKMGVGKVCPTAVFFFSAAGQIEYYN
                     LQCITKDALTTFQ"
BASE COUNT         2451 a         1820 c         2228 g         2151 t
ORIGIN      
        1 cgcggcccgg cagggacggg gcaggccgtt tttccgggag tggctacact ccctatgctt
       61 gctacgttac tgtttctcca ctaacaagac gtttccaaag ccccaaacta cccgcaaaat
      121 agccctctgg aaagaaaaaa gtgcaaaaaa atagaagcta cgctgtgcag ctcccgctaa
      181 aagtaaaaca gaggatgcca gttacacatc ctccgtttca ttcttcttcg gcttttcaat
      241 tagtatggcg ctgtcaatcg cgccctcgat gatcggcagg tattcttcgg ggcagagttt
      301 cagcttgtgg ctgacccttt gccgcagttc gctttcctcc cgcatgatct ccgggttaaa
      361 gtagcgttcc acaggaagcc cgcaggcttt aataagctgt atgacaaccg gcagactggg
      421 aatggccccg tcgttttcga tgttggcaag atagcgccag tcaatattta ttttctctgc
      481 cattgctttg cgcgaaacgc gctttgcttg ccgggccgct ttcacatccg cgccgaaagt
      541 ttcaaagccg ggacaatctt caatattcgc catatcgcac ctcccactta cattgtatat
      601 ttcatactct gcccgtggaa tgttggtata tgcacctttc ttaaagttta tatttcacat
      661 tttgtttctt ttattcttcg agcaaaagaa ttataatgta ccctgtggag gtgtactatg
      721 gactacatga cgttgaaaga ggcaggcgag aaatggggtg tgcccccacg atggataaac
      781 tactattgtg ctgcgggacg catccccggc gctgtaaaga tggcgacgat ctggctcatt
      841 cccaaaactg cggaaaagcc gattgacagg cgtacaaaga aaggaaaggc ggttactgaa
      901 tagtataatg aaaccggcgc attttggata tggttttgaa gagagagaaa gcatggtatt
      961 ttgtcacgga aaaactataa gatgatagat ggcaggctgc tccagaccga taaaaagtat
     1021 tctcatctga aacagaaaga aaagatttac acatggatgt atgaagaagc gaaactttat
     1081 catgacagaa atggaaaatg cccgaaacaa agacgaggaa gctgctgctg tatcagccgt
     1141 atatggtaga attgaaaagg ccggcatctg gattctttat ggtgaagtct ccagacattg
     1201 gataactgct ggtctaatgc gcctttgagt atggggtgat tgattttaat accggggagg
     1261 tacggctttt tgaggaaaat attctgggat ttacatttgg cgattattac atttcctgta
     1321 actgcaagga cacggatgat gaagatatga ggaatataga cttgctgatt ttctactgtc
     1381 ttgaacggta ttaggactga atctgctgcg cggagtgcgg caagagcgac cggagggagt
     1441 acacacaggc cctgcctgtg tgaaaagcca taccgcaagg tgcattcgca aaaaagaggc
     1501 cgcgcatttt gctgaggctt ggggtgtccc caacaagcaa aacgagaacg ccgcaggcgg
     1561 gcaagtggtg gatcagaata tccgtaaagg atattctgat ccattgcttg ccagtattat
     1621 cgggatgttt tgacaaccgc tgtaatcgaa acatcccaaa cattaagaag gtgttaatta
     1681 ttattatctt gatttaattc gtttaaacca ataatataga tacatacacc atgaaaagaa
     1741 gcgagtatcc caatgacgga tgattaaaat ccgaaaagaa atcgctttga aactacaggg
     1801 aaactacaga ctgttatgtt atcttcttaa aatggaggga tttttatgtc gatacgaatt
     1861 ctacttgtcg aggatgatga tcatatctgt aatacagtaa gggcgtttct ggctgaggca
     1921 ggatatcagg tggatgcctg cacagatgga aatgaggcat acaccaagtt ttacgaaaac
     1981 acttatcaac tggttattct tgatattatg ctgcccggta tgaacgggca tgaacttttg
     2041 cgtgaatttc gtgcgaaaaa tgatactccc attctgatga tgacagccct gtcggatgac
     2101 gaaaaccaaa tccgggcgtt tgatgcagag gcagacgact atgtaacaaa gccattcaag
     2161 atgcagattt tactaaagcg ggtggaagcc ctgctgcggc gcagcggtgc gctggcaaag
     2221 gaaatccgtg tcggcaggct gacacttctg ccggaggatt tcacggtact ttgtgacggt
     2281 acagagctgc ccctgacacg aaaagaattt gaaatccttt tgctgctggt gcagaacaaa
     2341 ggcagaacct taacgcatga aatcattttg tcacgtatat ggggatatga ctttgagggt
     2401 gatggcagca cagtccacac tcatatcaaa aatttgcggg ccaagctgcc ggaaaatatc
     2461 atcaaaacca ttcgcggtgt aggataccga ttggaggaat cataataatg gaaagaaaag
     2521 ggattttcat taaggttttt tcctatacga tcattgccct gctactgctt gtcggtgtaa
     2581 cagcaacact gtttgcacag caatttgtgt cttatttcag agtgatggaa ttacagcaaa
     2641 cagtaaaatc ctatcagcca ttggtggaac tgattcagaa tagcgatagg cttgatattc
     2701 aagaggtggc agggctgttt cactacaata accaatcctt tgagttttat attgaagata
     2761 aagagggaag cgtactctat gccacaccaa atgccaatac atcaaatagt tttagacccg
     2821 actttcttta tgtggtacat agagatgata atatttcgat tgttgctcaa agcaaggcag
     2881 gtgtgggatt gctttatcaa gggctgacaa ttcggggaat tgttatgatt gcgataatgg
     2941 ttgtattcag ccttttatgc gcgtatatct ttgcgcggca aatgacaacg ccgatcaaag
     3001 ccttagcgga cagtgcgaat aaaatggcaa acctgaaaga tgtaccgccg ccgctggagc
     3061 gaaaggatga gcttggcgca ctggctcatg atatgcattc catgtatgtc aggctgaaag
     3121 aaaccatcgc aaggctggag gatgaaatcg caagggaaca tgagttggag gaaacacagc
     3181 gatatttctt tgcggcagct tctcatgagc taaaaacgcc catcgcggct acaagcgttc
     3241 tgttggaggg aatgcttgaa aatatcggtg actacaaaga tcattctaag tatctgcgcg
     3301 aatgcatcaa aatgatggat aggcagggca aaatcatttc cgaaatactg gagcttgtca
     3361 gcctgaatga tgggagaatc gtacccatag ctgaaccgtt ggacataggg cgcacggttg
     3421 ccgagttgct gcccgatttt caaaccttgg cagaggcaaa caaccagcgg ttcgtcacag
     3481 atattccagc cgggcaaatt gtcctgtccg atccgaggct gctccaaaag gcactatcca
     3541 atgtcatatt gaatgcagtt cagaacacgc cgcagggagg cgaggtacgg atatggagtg
     3601 agcctggtgc tgaaaaatgc cgcctttttg ttttgaacat gggcgttcac attgatgata
     3661 ctgcgcttcc aaggctgttc accccattct atcgcattga tcaggcgcaa agcagaaaaa
     3721 gtgggcgaag cggtttagga cttgccatcg tacaaaaaac gctggatgcc atgagcctcc
     3781 agtatgcgct ggaaaacacc tcggatggcg ttttgttctg gctggattta ccgctcacat
     3841 caacattgta aatatttaaa acttaaatga ttttgaccga caggtataac cctgccggtc
     3901 tttttttgct gctacaggaa aactacagac tggctacagg gaaagtacag atgcgcttgc
     3961 cataataaca atcgtaccag ccacaaatcg tagttttatt gcaaaggagg cattcgatca
     4021 aatggaaaaa agcaactatc attccaatgc ggatcatcac aaacggcata tgaaacaatc
     4081 cgtggaaaag cgggcttttc tatgtgcgtt cattatttcg ttcacagtct gcacgctgtt
     4141 tttggggcgg agactggctt ccgtattgga ggcaacacag ataccgccca tccctgcaac
     4201 tcatacaggc agcagcactg acgtagtgga gaatttggag gaaaacgctc ttgccaccgc
     4261 caaagaacag ggagatgaac aggaatggag cctgatttta gtgaacaggc agaaccccat
     4321 ccccgcacag tacgatgtgg agcttgagca actatcaaat ggtgagcgga tagatattcg
     4381 gatttctccc tatcttcaag atttgtttga tgccgcaaga actgatggag tttacccgat
     4441 tgtcgcatcc ggataccgaa caacagaaaa acagcaagaa attatggatg aaaaaattgc
     4501 cgaatataag gcgaaaggct acacctctgc acaggctaaa gcggaagcag aaacttgggt
     4561 ggccgtgccg ggaacgagcg agcatcagct tggtcttgct gtggatatca atgcggacgg
     4621 aattcattca acaggcaacg aggtttatag atggctggat gaaaacagct atcgttttgg
     4681 ttttattcgt cgctacccac cagacaagac agagataacc ggtgtgagca acgagccgtg
     4741 gcattaccga tatgttggca tcgaagctgc cacagagatg tacaaccaag gggtttgcct
     4801 tgaggaatat ttaaaaccag aaaaatgaga aaaggatgtt atgttatgga cagaaaaaga
     4861 ttgacacagc gtttcccgtt cctgcttcca atgagacggg cgcagagaaa aatgtgcttt
     4921 tatgcgggaa tgagatttga cggctgtcgc tatgcgcaga cgatagggga aaaatcgctt
     4981 tcccatttgc tctttgaaac ggattgcgca ttatacaacc acaataccgg atttgacatg
     5041 atataccagg aaaacaaggt gttcaactta aagctggcag caaagacctt aaacggctta
     5101 ttgataagac cgggggaacc cttttctttc tggtggctgg tacgccatgc ggacaaagat
     5161 accccctata aagacggcct tacggtgacc aatggtaaac tcaccaccat gtcgggcggc
     5221 ggtatgtgcc agatgagcaa tttactattt tggatgttcc tgcatacgcc attgacaatt
     5281 atccagcgca gaggtcacga agtaaaggag tttccagagc caaacagtga cgagattaaa
     5341 ggggtggatg caaccatttc agagggctgg attgatttaa aagtgcgaaa cgataccgac
     5401 tgcacctacc aaatatgggt gaccttagat gatgagaaaa tcatcggtca ggtgtccgcc
     5461 gacaaagagc cccaagcatt atacaaaatt acaaatggca gtatccagta tgtccgtgaa
     5521 agtggcggga tttatgaata tgcccaggtt aaacggatgc aagttgcctt aggtaccggg
     5581 gaaataatag attgcaagct gctttataca aacaaatgca aaatctgtta tcccctcccg
     5641 gaaagtgtgg atattcagga ggagaaccaa tgagaaaaag tgtgggcatt actgtttttg
     5701 gatgcgaaca ggatgaggca aatgctttcc gcgctttatc gccggatttt catattatcc
     5761 ctacgctgat tagcgatgcg atatcggcag acaacgcaaa attggccgct ggcaatcaat
     5821 gcgttagcgt aggccataag tccgaggttt ccgaggcgac aattcttgcg ctgagaaagg
     5881 tcggggtaaa atacatttct acccgcagca tcggctgcga tcacattgat acgactgccg
     5941 ccgagagaat gggaatctcg gttggcacgg ttgcgtattc gccggacagc gttgcggatt
     6001 atgctttgat gctgatgctg atggccatac ggggtgcaaa acccaccatg cacgccgtgg
     6061 cgcaacaaga tttcagattg gatcgtatcc gggggaaaga actgggggat atgactgtgg
     6121 gagttattgg aaccggccat atcgggcaag cggtcgtcaa aaggctgcgg ggatttggat
     6181 gccatgtgct ggcctatgat aacagccgaa aaatggatgc agattatgtc cagcttgatg
     6241 agcttctaaa aaacagcgat attgttacgc tccatgtgcc gctttgtgcg gatacccgcc
     6301 atctgatcgg tcagaagcaa attggagaga tgaagcaagg cgcattttta atcaacaccg
     6361 ggcgcggagc gcttgtcgat accggggcgc tggtggaggc gttggaaagc ggaaagctgg
     6421 gtggtgcggc actggatgtg ttggagggcg aggatcagtt tgtttatacc gattgctcgc
     6481 agaaagtgct tgaccatccc tttttgtcgc agcttttaag gatgccgaat gtgatcatca
     6541 caccccatac ggcgtactac actgagcgtg tgctgcagga tactacagaa aaaacaatca
     6601 ggaattgtct caattttgaa aggagtttac agcatgaata gaataaaagt cgcaatcatc
     6661 ttcggcggtt gctcggagga acatgatgtg tcggtaaaat ccgcaataga aattgctgcg
     6721 aacattgata cggaaaaatt cgatccgcac tacatcggaa ttacaaaaaa cggtgtatgg
     6781 aagctatgca agaagccatg tacggaatgg gaagccgaca gtctccccgc catactctcc
     6841 ccggatagga aaacgcatgg gctgcttgtc atgaaagaaa gcgaatacga aacacggcgt
     6901 attgatgtgg ctttcccggt tttgcatggc aaatgcgggg aggatggtgc gatacagggg
     6961 ctgtttgtat tgtctggtat cccctatgtg ggctgtgata ttcaaagctc cgcagcttgc
     7021 atggacaaat cactggccta cattcttaca aaaaatgcgg gcatcgccgt tcccgaattt
     7081 caaatgattg ataaaggtga caagccggag gcgggtgcgc ttacctaccc tgtctttgtg
     7141 aagccggcac ggtcaggttc gtcctttggc gtaaccaaag taaacggtac ggaagaactt
     7201 aacgctgcga tagaagcggc aggacaatat gatggaaaaa tcttaattga gcaagcgatt
     7261 tcgggctgtg aggtcgggtg tgcggtcatg gggaacgagg atgatttgat tgtcggcgaa
     7321 gtggatcaaa tccggctgag ccacggtacc ttccgcatcc atcaggaaaa cgagccggaa
     7381 aaaggctcag aaaatgcgat gattacagtt cccgcagaca ttccggtcga ggaacgaaat
     7441 cgggtgcagg aaacggcaaa gaaagtatat cgggtgcttg gatgcagagg gcttgcccgt
     7501 gttgatcttt ttttgcagga ggatggcggc atcgttctaa atgaggtcaa taccctgccc
     7561 ggttttacat cgtacagccg ctacccacgt atgatggccg ccgcaggaat cacgcttcct
     7621 gcactgattg acagcctgat tacattggcg ttaaagaggt gataagtatg gaaaatggtt
     7681 ttttgttttt agatgaaatg ttgcatggcg tccgttggga tgccaagtac gccacatggg
     7741 ataacttcac aggaaaaccg gtggatgggt atgaggtgaa tcgcatcatc ggcacaaagg
     7801 ccgtggcgtt tgctctgcgc gaggcacaaa tccatgcggc tgcgcttggc tatggcttgc
     7861 ttttatggga tggatatcgg ccaagaactg cggtggactg cttcctgcgt tgggcagcgc
     7921 aaccggagga caatctcaca aaagaaaaat tttaccccaa tatagagcga gccgagttga
     7981 ttacaaaggg ttatgtggcc tcacaatcca gccatagccg tggaagcgca attgatctta
     8041 cgctctacca cctggataca ggggaacttg tttcaatggg aagtaacttc gattttatgg
     8101 acgaacggtc gcatcataca gcaaaaggga taggggatgc agaggcacaa aatcgaagat
     8161 gcttgcgtaa aatcatggaa agcagcggat ttcagtctta tcgctttgaa tggtggcact
     8221 ataagttgat tgatgagcca taccccgata cctattttaa ttttgccgtt tcataatgaa
     8281 agtattggtt ttgtatcaga ttttggattt gataaaatct atgctggtca tggacaatct
     8341 tttactggaa agtggttaaa gcatcttttg taatacattg caaattatag tattcaatct
     8401 gcccagcggc agaaaagaaa aaaaccgctg ttgggcagac ctttcccacg cccattttgt
     8461 attttgctgg cggcggtttt gagaaatcaa ggccgccgtt cttttctggc agcaaaaggt
     8521 gtggcggccc ataggaggat gccgctatgc tgttttgcta ttgccatgct ctaatccact
     8581 tccaccactc aaaaaaagcc ttgcccctcc atgaactgaa ccccaaaagt tgaactattt
     8641 aatggactgt
//
LOCUS       DAZUJR010000228         7757 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.guided.111, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000228 DAZUJR010000000
VERSION     DAZUJR010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7757
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.guided.111"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            44..679
                     /locus_tag="ACG804_003025"
     CDS             44..679
                     /locus_tag="ACG804_003025"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFS4833860.1"
                     /translation="MARNKYPEETVKLILDVSTKMFCEKGYDNTSLQDIINETKLSKG
                     AIYHHFDSKEDILKAIFQRIGNENAVIFAKIRDNDSLNGLEKLREIFKTAVFNSNQSV
                     LLTVSPQLLNNPRFLAMQIEQMYEIVVPEFVEPVLEQGIKDKSLEIENSHEIAEVIMV
                     LSNVWLNPLVEMTDKEGMEKRCNTFNALLNGIGIDTLLDEETISAFIQFCK"
     gene            786..2024
                     /gene="mef(H)"
                     /locus_tag="ACG804_003026"
                     /gene_synonym="mefH"
     CDS             786..2024
                     /gene="mef(H)"
                     /locus_tag="ACG804_003026"
                     /gene_synonym="mefH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_070509550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide efflux MFS transporter Mef(H)"
                     /protein_id="HFS4833861.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSVSVLLMGISLFLELPAIVSYWVVTVMCFVAMGVSTM
                     FVVQIYTLVQTQTPPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVA
                     SIASIMISIYSKRIFQKLEI"
     gene            2251..2670
                     /locus_tag="ACG804_003027"
     CDS             2251..2670
                     /locus_tag="ACG804_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HFS4833862.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
     gene            2675..2914
                     /locus_tag="ACG804_003028"
     CDS             2675..2914
                     /locus_tag="ACG804_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4833863.1"
                     /translation="MSKDYGYPSFELICKASSGDEMAVKEILKFYDGYISKLCLRPFY
                     HSESGKIIMQVDEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(3139..4062)
                     /locus_tag="ACG804_003029"
     CDS             complement(3139..4062)
                     /locus_tag="ACG804_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HFS4833864.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            complement(4094..4858)
                     /gene="map"
                     /locus_tag="ACG804_003030"
     CDS             complement(4094..4858)
                     /gene="map"
                     /locus_tag="ACG804_003030"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HFS4833865.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            5016..5456
                     /locus_tag="ACG804_003031"
     CDS             5016..5456
                     /locus_tag="ACG804_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HFS4833866.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            complement(5634..6203)
                     /locus_tag="ACG804_003032"
     CDS             complement(5634..6203)
                     /locus_tag="ACG804_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFS4833867.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            6458..7690
                     /locus_tag="ACG804_003033"
     CDS             6458..7690
                     /locus_tag="ACG804_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HFS4833868.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
BASE COUNT         2496 a         1338 c         1432 g         2491 t
ORIGIN      
        1 gatatacttt aatcagacca acggtttgta ttggaggtaa gttatggcac gaaataaata
       61 tccagaagaa acagtaaaac tcattttaga tgtttctaca aaaatgtttt gtgaaaaagg
      121 atatgataac acatcattgc aagatattat caatgaaaca aaactttcta aaggtgctat
      181 ttatcatcat ttcgattcaa aggaagatat tttaaaagca atttttcaaa gaattggaaa
      241 tgaaaatgca gtaatatttg ctaaaattag agataacgat agtttaaacg gtttagaaaa
      301 gttaagagaa atatttaaga cagcggtatt caattctaac caaagcgttt tattgacagt
      361 ttctcctcaa ctattaaaca atcctcgttt tcttgctatg caaatagaac aaatgtatga
      421 aattgtagta cctgaatttg ttgaacccgt tttagaacaa ggtatcaagg ataagtcttt
      481 ggagattgaa aattcacatg aaattgcaga agttatcatg gtattaagta atgtatggct
      541 caacccatta gttgaaatga cggataaaga gggtatggaa aaacgttgca atacattcaa
      601 tgccctttta aatggaatag gcatagacac attattagac gaagaaacaa tttctgcatt
      661 tatacagttt tgtaaataac tgtatttgtt atccctatac gatagactgc tctataaaag
      721 agcagtttat ttaaaccatt atataaaccg acggtctgtt tgattaaata aaaaggagag
      781 attttatgca agcagaaaaa aaacttttta atcgtgattt tatacttgtt gttataggac
      841 agataatttc tttatttgga aacgctatcc tacgatttgc attaccgtac tatttgttaa
      901 aagaaactgg ttcatcagct ttgtttggta ttgctacagc ctgctctttt ttacctatgg
      961 ttattttgtc gctggtaggt ggtattattg ctgacaggac aaataaaaga aacattatgg
     1021 tcatactaga ttttgtaaca gcaatcataa ttttagtatt ttatttgtca ttgggaaaaa
     1081 ttcctatcat acctttgttt attgttgctt tgatgttact ttatggtatt tctggtgcat
     1141 atcaaccagc ggtacaagca agtattcctc tattggtatc atcagataaa cttaccgtcg
     1201 gtaatgctat aataaatcaa gtaaatactt tagcaaactt tatcggacca gctataagcg
     1261 gagtagtttt tcaattttat ggtatcaatc ccattttaat tgttagtatt atatgtttta
     1321 ctttttcagc cattatggaa atttttatcc atattccaca ccaaaaaaga cctcgtgaag
     1381 taggtgtaat tgcagttgct aaaaacgatt taaaagatag ttataccttt ttgaaaaagg
     1441 agaaacccat ttttatatcc gtaatctttt tggtttgcat tttcaatttg gttttaagtg
     1501 ctgttttaat tgttggtctg cctatcttaa tttctgaagt tttaaaaatg ccagatacac
     1561 tatatggttt ttcacaatca gcattatcat taggtggttt atgtggtggt attttaacag
     1621 ctcttgttgc ttcaaagtta aaactaaaaa acctttatac cttgttactt atttgttctg
     1681 tttctgtttt acttatggga atttcgctat ttttagaatt gcctgcaata gtttcctact
     1741 gggtagttac agtgatgtgc tttgtggcta tgggtgtatc tactatgttt gttgttcaaa
     1801 tttacactct tgttcagaca caaacaccac cgcaattagt aggaaagata atggctacgc
     1861 tggtagcagt tgctatgtgc ggtcaaccta ttggacaaat ggtttacggt attttattcg
     1921 atgtatttat acaagaaaca tgggttgtta tgtttgtagc ttctattgct tcaatcatga
     1981 tttcaatata ttcaaaaaga atttttcaaa agttagagat ataatacaag gggttaaata
     2041 gtatgttagg ctaaaaacaa tatataaaag aaaatttgaa atctgctaaa aggatagtgt
     2101 tataaaagaa agagtaatat tgcagtattt aaggctcgca caaatatatg ttttgtgtgg
     2161 gcttttttct taccattttt ctgtatttct aaagggtata aacggtattc cgtttatata
     2221 tttcagcatt agcagaaagg gggtgagatt atgaggacat cttctttcga gcatatcgtc
     2281 agattacagt tcaattcttt aatgctgatt gtcattaaga acaaagtgaa aagtcgaaac
     2341 agacagcttg caagacattc taaacgtgaa gtattgtttt gtgaaatagc cgaaacgaaa
     2401 caagttgaac gtggaacgat tgatacctgt ttttatgatt gtgtatcatt taaagtcttg
     2461 cactttacaa tttatgtatc tgatgaaaca cttggtacag ttttacatag actgtcagaa
     2521 aaacagcgta gtgcgatttt attacgttat tttcaaggaa tgaacgacag agaaatttca
     2581 gaactgtacc atgtatcacg ttctgctatt tgcagtagaa gaactagagg actaaggaag
     2641 ttaaaaatgc ttttgagcga aaggaagtaa agaaatgagt aaagattatg gctatccctc
     2701 ttttgaattg atttgcaaag cgtcaagcgg agatgaaatg gcagttaaag agattttgaa
     2761 gttttatgac ggttatattt ctaaattatg cttgcgtcct ttttaccact ctgaaagtgg
     2821 taaaatcatt atgcaggttg atgaagaact aaaaggagaa attcatacag acatgatgaa
     2881 agcaatattg aaatttgaaa tcggagtgaa gtaatcaact gtataaaaaa atcgggagat
     2941 acacagtttc gtgctatctc ccttagtagt tttacggtca tatcaaggct cattcaatcg
     3001 tggtaaattc gtggtaagat gagtgttttt ctatacttca aaatgcttga atgtatagtg
     3061 tttatgcgga taattgaaaa ttagatataa aatttcaaat aaattactga tataaattta
     3121 caataagaac tcttgtttct actttttttt atgagaaaat ttagttttca atttattgaa
     3181 ccattttcgg cttggatctc gacgtttttt gatttgatga cccgtcacgt attcttgaac
     3241 aactgcattg atgattccgc ccaaaatgat gatcgtagca gcaaaattaa gccaaagcat
     3301 gagtacaata aaacttccta tgatctgata accgctgatc ctcgttgcaa aatacctagc
     3361 atagatacta aacacttgtg ataacagcat ccagccgaca gtagcgaaga tcgtgcccgg
     3421 aatgatcgtc ttcaacttca actgagcatt agggacaatt aaataaatca agaacatgat
     3481 gacaaataaa gctaccaatg tgattggcca cttcaaagtt tggaactgat cgataaagtt
     3541 cacgggtatt tgtacgattg gctgaatagc atccaaaatc agctgtccca acccaagaac
     3601 gatagttacc ccactaatag caatcatgaa caagacaatg acaattagtg agaagaaacg
     3661 gacgatcaaa aaattttttc tattttctac gccatacgct ttattcatcg caatttgcaa
     3721 agcattgata ctttgacttg cagaccataa agccgctaat gcagaaacgg ataacaagcc
     3781 tcctgaactt tgtgtcaaaa ggtctttgat tgcaggaccg ataaactggt aaacggtctc
     3841 aggaatcact tctcgtaaat aggtcagtac agtctcttga tcgatgtgga gaaacggtaa
     3901 aatattacca aaagcaataa tcaatggaaa taaagacaag agtaaataat aagcaacgac
     3961 gacagaggtc gtactcattt ctgaatcagt gatgcgcttt tgagtcgtct caataaagcg
     4021 catcagattt tcattttgtt ttattttgtt ccaaactttc atgtacctct cccgtaccta
     4081 ttgactggat agatcaataa gtgccttctt ctccttgtga tgtcaaaatt cttggaccat
     4141 ctttagtaat agccaatgta tgttcatatt ggcaagaaag tccgccgtct cttgtatacg
     4201 cagtccagcc gttaggatcc attttcattt tccaagttcc ggtattaacc ataggttcga
     4261 tcgtgataac catgccttct ttcaaccgca acccttttcc agcttctccg taatgaggaa
     4321 ctgctggttc ttcatgaatc gtaggaccaa cgccatgacc aataaaatca cgaacgatcg
     4381 ctagattttc gccttctaca taagtttgga tagcatgacc gatgtcacca atccgattcc
     4441 ctacttgtgc ttgctcaata ccgatgtaca aagctttctt cgttacttcc atcaatcggt
     4501 cgatctcagg tgtagattct ccaactacat aggcccaaca agaatcagaa atgccgcctt
     4561 tcaaatcgat acacatatcg acttttacca aatcaccgtt tttcaaaggc tttttacgag
     4621 ggaatccatg acaaatttca tcatttatac tgatacaagt cgcatattca tacccttcaa
     4681 agccaatttg cgcagcaatt ccgccatgac tctcgatata gtttctgaca aatacctcaa
     4741 tatcccaact tgtgattcct ggttttataa aatcacgcag atttttatgt acatctgcta
     4801 ataaagctcc agattctgcc atcatttcaa tttcacgtgc tgattttaaa gtaatcatat
     4861 tttcgtctcc tttttacaaa tccctctcat tttaacatag cggcatacat ttagccaaat
     4921 gacattcccc aggtgtctct aggttttatt ttcttttcaa tgatgttttg gtataattca
     4981 taattgttaa ataattataa acgaggaggc acatcatggc tttagcaaaa atcgtatatg
     5041 ctagcatgac aggaaacact gaagaaatcg ccgatattgt tgcagaagca tttgaaaatc
     5101 tggatatcga agtcgaaatc aacgaatgta cccaagtaga tgcagatgaa ttcgaggagg
     5161 cagatatttg cgtagtagct acttatacat acgatgatgg cgatctgcct gatgagatcg
     5221 tagactttta tgaagacttg caagaattgg atctattggg aaaaatttac ggtgtctgcg
     5281 gatctggtga tactttttac gatgaattct gcaaatcggt ggatgatttc gatgctgctt
     5341 ttgcaaaaac aggcgcatca aaaggagccg aaaatgttaa agtggatctg aatgctgaag
     5401 aagaagatat cgaaaattta gaagctttcg ctaaagaact agtcgcaaaa atttaatata
     5461 cttgcaataa aagagccatc cagatttatt caatctgtat ggctctttta ttcattgcat
     5521 tcatggaaga gttcttcggg agttaaaaat gcatacgctg taagaaaaac gaacttttcc
     5581 ttattttgac acatctcttg ttacctactg atttgtggaa cttttgagta tattcaatcg
     5641 atttcgattg gttctttgaa tttcaagata gcatctatac tgtcttggat catcttttca
     5701 atctgttcat cagttggatg gatgatgctt gaagacatca aagctgcgat cccagtagct
     5761 atgatccatg tcccattata caaagattcg atctgctctt ctgaaagatt cacataagct
     5821 ggatcgcgtt tcactgtatt cacaaagtaa gtataagaga aattctgcat ctcttttcct
     5881 ccaccatatt cttctaagta cagtgaacga tacaacttct tctctcttct tgcaaaatgg
     5941 atataattaa aagcaagatc gataatcgta ttccctgtat gctcaacagt gaacacttca
     6001 tattgtaaat gatcatagat ctgctcaaaa agagcttgtc tcaagtcatc catattttta
     6061 aactcaagat aaatcggttg cgtggaacaa ttcattttgt tcgcgatgtt tctcgcagta
     6121 aatcgtgtaa atccatcggt ggcagctact tcataagcag ctgccaaaat ctgttctcta
     6181 gtaatcgtct tttttcttgc catatttttt aatctcctta atttttttat aacgcttcca
     6241 ccattgatta atttcattgt aacatgtttt ttttgatatg caaaattagt ttttgatttt
     6301 cttcacaagc tgaaatagca agtagtaaca tatatcatga aacttaacct taaaaaaata
     6361 acctcctttt tttatttaaa gcctcattgt ttgaatcata attaaatggt atcatgctaa
     6421 tagttaccag aaaaaatggt gaggaggaat ttttattatg ttatctgatt ttaatgaact
     6481 tctaaaaaaa tatgcacgct taattgcaga aactggcgta gccacagaaa aaggacacac
     6541 agttgtttta cagatcagcg tggaacaggc accccttgct cgattgatca cacaagaagc
     6601 ttataaacta ggagccgctg aggttatcgt tcaatggact gacgaccaga tccaaagaga
     6661 atttctttta catgctgcaa cggatcgtat tgagaatgta ccacaatcta aaatcgatca
     6721 agcggatgaa tggcttgaaa aaggagcaag caggatcagc gttgtttctg ccgatcccga
     6781 tgcatttgct ggtgtagata gccatcgagt agcgtcttat caatcagcga atggcaaagc
     6841 actaatgaat ttacgcaagg caactcaagc aaataaagtc agttggactg tcgtggctgc
     6901 ggctggtaaa caatgggcag caaaagtctt cccagaactg ccagaagaaa aacaagttga
     6961 ggcattatgg gatcagattt tcaaaacgac tcgtgtctat gaagaagacc ctgtcttagc
     7021 atggaagaag catgatgaaa aattagcaaa aaaagcagaa gaattgaatc gagaacaatt
     7081 ttctgccctt cactatactg ctcccggtac agatatcatt atcggattgc ctaaaaacca
     7141 tctttgggaa ggcgctggaa gctataatgc tcgtggagaa aaattcatgg caaatatgcc
     7201 gacggaagaa gtgttcacag cacctgacag tcatcgagta gatggttaca tttcaagtac
     7261 aaagccactg agttatgctg gcaccatcat ctcgggtatg aaatttactt ttaaagatgg
     7321 aaaagttgtt gatttttctg ccgaacaagg agaagatgtc ttagcaaaac tgcttgatac
     7381 agatgaaggt gcgcgtcgtt taggagaagt cgcacttgta cctgaccctt cacctatttc
     7441 tcaatctggc atcatctttt tcaatacatt atttgatgaa aacgcatcga atcacttagc
     7501 actaggttct gcttatgcct tcagtgtgaa aggcggtaca gaaatgtccg atgaagaatt
     7561 agcagaagct ggattgaata gaagtcaaac ccacgtagat ttcatggtag gatctgacaa
     7621 gatggatatc gacggaatcc gtgaagatgg ctctacagta ccgattttcc gaaatggcga
     7681 ttgggcttga gtatactttc gcacacatgc aaaaaataat ggctctttgt caataaggac
     7741 tgatgagttg tgcaaaa
//
LOCUS       DAZUJR010000229         4636 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.guided.143, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000229 DAZUJR010000000
VERSION     DAZUJR010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4636
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.guided.143"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            126..623
                     /gene="dfrG"
                     /locus_tag="ACG804_003034"
     CDS             126..623
                     /gene="dfrG"
                     /locus_tag="ACG804_003034"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HFS4833869.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(695..2647)
                     /locus_tag="ACG804_003035"
     CDS             complement(695..2647)
                     /locus_tag="ACG804_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HFS4833870.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2654..2890)
                     /locus_tag="ACG804_003036"
     CDS             complement(2654..2890)
                     /locus_tag="ACG804_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833871.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            3292..3582
                     /locus_tag="ACG804_003037"
     CDS             3292..3582
                     /locus_tag="ACG804_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4833872.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(3854..4203)
                     /locus_tag="ACG804_003038"
                     /pseudo
     CDS             complement(3854..4203)
                     /locus_tag="ACG804_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741963.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            4296..4598
                     /locus_tag="ACG804_003039"
                     /pseudo
     CDS             4296..4598
                     /locus_tag="ACG804_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6056 family protein"
BASE COUNT         1479 a          758 c          813 g         1586 t
ORIGIN      
        1 gtattatgat aatataactt atagaaaaaa ttgcttattc aactaacggg caggataatg
       61 agaaaaggtt ttttgataga aataagaaat tagatggtaa attagttaaa aaggctgtgt
      121 tataaatgaa agtttctttg attgctgcga tggataagaa tagagtgatt ggcaaagaga
      181 atgacattcc ttggaggatt cccaaggact gggaatatgt taaaaatact acaaagggac
      241 atccgataat attaggtagg aagaaccttg aatcaatcgg aagagcctta cctgacagaa
      301 gaaatattat tctgacgaga gataaggggt ttacctttaa tggttgtgaa attgttcatt
      361 caatagaaga tgtttttgag ttatgtaaaa acgaagaaga aatttttatt ttcggaggag
      421 aacagattta taatttgttt ttcccttatg ttgagaaaat gtacatcaca aaaatacatc
      481 atgaattcga aggagatact ttttttccag aagtgaatta tgaggaatgg aatgaggtat
      541 ttgcccaaaa agggataaag aatgataaaa atccgtataa ctactatttt catgtatatg
      601 aaagaaaaaa cttattgagt taacgggtgc gttaattgaa gaagaacagt aaagataaag
      661 cacaagagct tgggattact ccaagctctt tttgtcattt gaaataaatt atatctttcc
      721 aatcaaattg tttatctgta atccctaatc tttgagcagg tgtcaaaacc tttttatccg
      781 ctgatttaaa agggcgacaa aagttgtagt aagttcttag aattgtaatc gcaaattgag
      841 catacttcgg attgaagtta gcgtaaatat agctcttctt atcaccacga gctgttgtta
      901 atggtctttc aagagatgat atataacgtc ttatctgttg aataaagcta ttggtcgaat
      961 ggtcattaac atttaatagc atctttgcga tttcgtttgg ttccagagca gataaatccg
     1021 ttctacaatc aactgaataa aatcctttat ccttagtggc taatggatgt ttgatagggt
     1081 tatcggcata tttgcgatat ctttctccat ctttactaat agcctcttcg tggaattgat
     1141 gacttgttag taattcagtt agataatgag atgccaaagt ccgtagaaac tttgttttga
     1201 atcctctgat atctccccaa tcgagcagtt ctgcttttgc ttgtccgaat tcttttaagc
     1261 attgttttct gcttttcgtc ttgttaactt ggcaaataaa atgatgtgca tcgctcaacc
     1321 ttaattcttt cgtgaatact ctataaaagg cgtttctaat agagaagtca tcatcactaa
     1381 tcattcgcca ttcgtcggca ttaaccattt gtttaattaa ccaatagtga gcagttgtag
     1441 tataaggagc atcaacattt aaaccatcga caaatctact cctattagta attttcccta
     1501 attcgtgaag ataagcattc ctattttcgc tatcgttagc ggatggttct tgtggataat
     1561 aagaccaatc taacctatca tttttacgac taaaagtatt gagatggtct tctttgaatt
     1621 ttcttgtatc ttcatttaat tcatccattg aaatattcca atcataggca acatcagaac
     1681 ggaacacata tcttgataag acctcagcag atacaactat atacgtttgc atattaaggt
     1741 cttcaaaccc cgtatatttc tttgaacctt gtcctttctt acggacgtta tttaggtagt
     1801 agtgcatctt gtccgtatta agccacatct cgttaaattt ctttgtttga aggggttgtg
     1861 tctcatatcg ttctaaaaac tccaaacaac gcctatacag ccactccagc ttatgatagt
     1921 aggttccaac tccaattcct aaaatatcac aagtacgact gactgaaacc cttccaacaa
     1981 ccatcttagc gaacattgga agaatggtgt tcttttgttg gtgataagta gtggtttctt
     2041 ctctttttgg tagaacatta gtgaacttct tacacgcctt acattgatag cgttgagatt
     2101 tgcccctact tttccccctt ttgtaaaatt gcttcggctc attgaatggg gttgattctt
     2161 cttccgagca gccttcttta tgaaattgat aatctggctc aacatcttgg atgctattga
     2221 tttctataag gcgtttaatt tcttcaacaa cagaccaatt agataaaggg gttactgtac
     2281 agttttgcga tacacctctg ccaataggat tgtcattgca gtacatacct ttatgacctt
     2341 tatctttgga actaccagtc attttatatc gacttggttt cccttttaca tctttgaatt
     2401 tgtgctgttc tttcccaaaa ttacaacaaa acggattgat gcagtaatta tattgaatgg
     2461 gatattcaga accgttccat ttaaaagacg ttggcaagaa caacattttg ttataccttg
     2521 ttgcaaatcg ttttggagtt aataaatcat attgtttagc cctatctttt aattcttcgt
     2581 ttgaaatcgg aattttaaca tctacaattt catcttcctt cgtggctaat cttttaagct
     2641 tggtcattgt ctatcaaccc actctatctt tgatacccat tttttcaaca atccgcttat
     2701 tacttcgctt gttggcaatc cattcaataa acttcttatc gtctaaaatg ttcaataaga
     2761 attcatccac tgcttcgctt tcagtacgct ctgcatattc agcgtattgc ttaactatca
     2821 cccttacttg ctctgatatt tcccaatcca cagacttagc gttcttattt tttggctcaa
     2881 gaaattgcat aggaaaatgc accccttttt gcttagtaaa ttgtaaccat tttaacacac
     2941 caatttgcat tcctacaata attatttcac gttcgcattt ttatatacat tttaacttac
     3001 attttgtggt gtaaattaac aacaaacgtt gatttaacaa taaaaaacga gtatcaaatt
     3061 cagttgcaat ttgatactca tttaggttta cattttcact ttttgtactc caaaactgaa
     3121 ctacttaaat ctatactgct gcctcttttt tttagtacat gtccttcatc ttcgcaggaa
     3181 gtgccaatat gattttaaga aaggtaatag acaaaaagtc aaaaagataa aacagagttt
     3241 cttctttaca aagggaatgt atgttcgtat aatggtattg aggtgaaggt tatggagaaa
     3301 aaatatggaa cagtagataa gatccgtact ttgcaagtta gtgccagacc gttgatccgt
     3361 ttcagtttaa atggggtcaa ttgtttgatt gcttcccata gtttgaactt cctagctgaa
     3421 gtagacgaag ggatgaagtt agtcgttaca ggttattata ataatagaaa gcaatttgtt
     3481 gtgagatcct atcatgtgtt agggaaaccc aaaattgtgg tagaatatga gaaaagtcta
     3541 tacccaagaa aaaaggtccg acaagatgaa agaataaact agaaaacaag cggctgagac
     3601 aaaaatgtcc tagccgcttg ttttggaaag atggatgcag acgatgggat ttgaacccac
     3661 acgagcatac gctcacaaga acctcaatct atatataact acatgtattt aagtatttgt
     3721 gatgaatcac taaactttcc aaactcattt gagggatatt gcttaaagat tgaacagatc
     3781 aattcgaagc cctattagta ttcgctcaat ggggggatca gaggccataa aaagagacta
     3841 gtcattacta gtctcaggta gtggaattgt aggattttaa acgttcctgg agagtaccgg
     3901 tatgtaactc gaagaggtga ttatcatagt cgtaaaagta aattgaagaa gcctcgcctt
     3961 tcacacgaga acgtcctggt tcgacagtta aacctaacat ttggattttt gagacaaacg
     4021 aatctatatc ttgttcgtca attttaaaag caatatgatt gtatgtcttt ggcagtttat
     4081 tcgacgaatt ctgcattact gcaatccata ggtccttaac taagaaaaat ttttctggat
     4141 ataatgaaaa tttttttgtt gactatcgta gatttctttt gcatcaaata aggtatttaa
     4201 caattaagta tttaaaagat aacttttaag ttatctttaa gtaatgctta aagctatgtt
     4261 atactctatt aggaaatata agaaggagta taaaaatgaa caaacataat agaaaaataa
     4321 cgaataacaa agaactgatc ttgttactaa tagggatttg gggtatcttt ttactcttta
     4381 atatgtatat gccgactatg agagcggatg acgtagttta tgcaagtaga ttagatgaac
     4441 ttggctattt gggtgcttcg atagaacatt ataagacatg gagttcaaga attattatag
     4501 aactattctt aatgttcttt tctaaacact ttatgctatg gaaattatta aattctacga
     4561 ttatgttagg aattgtagta ttactttgca agtatgttga gagtataaaa tattttgtgt
     4621 aaatgaaaaa atccat
//
LOCUS       DAZUJR010000230          876 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5370
            SAMEA115707675-rid22580493.guided.218, whole genome shotgun
            sequence.
ACCESSION   DAZUJR010000230 DAZUJR010000000
VERSION     DAZUJR010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707675
            Sequence Read Archive: ERR13197403
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288112.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288112.1
            Genome Coverage       :: 125x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:10:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,901
            CDSs (with protein)               :: 2,901
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 39 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..876
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707675-rid22580493.guided.218"
                     /isolate="VRE5370"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            263..811
                     /gene="aac(6')"
                     /locus_tag="ACG804_003040"
     CDS             263..811
                     /gene="aac(6')"
                     /locus_tag="ACG804_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HFS4833873.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          312 a          128 c          183 g          253 t
ORIGIN      
        1 tatttgtcaa ttcataattg gtttttttta aagcaaaaga taatctatat catgatgaac
       61 aaacagagtt ttttcctcca attgatggct ttcctgatct ttcctatttt gaataaagtg
      121 tttctgtata attttttatt ttataagtaa gataaataat gaaagaatag agatactgat
      181 tggtagctaa agatttttga gcgagaacat ttcgtttttt caaaaggact gttagaataa
      241 gcaagaacaa gggggaagac gtatgataat cagtgaattt gaccgtaata atccagtatt
      301 gaaagatcag ctttctgatt tactgagact gacttggccg gaagaatatg gagacagctc
      361 ggcagaagaa gtagaagaaa tgatgaatcc agaacgaatc gcggtagcag cggtagacca
      421 agatgagtta gtaggattta ttggtgcaat ccctcaatac ggtatcacag gttgggaatt
      481 gcatccatta gttgtagaaa gctcccgacg aaagaaccaa ataggtactc gattagtcaa
      541 ttacttagaa aaagaagtag cttccagagg aggaatcacg atttatttag gtacggatga
      601 tttagaccat ggaacaacgt taagtcaaac ggacctgtat gagcatacat ttgataaagt
      661 ggcttccatc cagaaccttc gtgaacatcc gtatgaattc tatgaaaaat taggttataa
      721 aatcgtaggt gtcttaccaa atgcaaatgg ctgggacaaa ccggatattt ggatggcaaa
      781 aacgattatt cctcgaccaa attctcaata ataaaaagag gttgtgacag aagtaatcag
      841 cttcaagaaa taagaaggaa tttacgaaaa ttactt
//
